UnificationXref1299
type: UnificationXref
id: REACT_3165
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3165.1

UnificationXref1297
type: UnificationXref
id: REACT_151424
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_151424.1

UnificationXref1298
type: UnificationXref
id: 113519
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113519

SequenceSite2589
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1291
type: UnificationXref
id: 4198002
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4198002

SequenceSite2588
type: SequenceSite
position status: EQUAL
sequence position: 598

UnificationXref1292
type: UnificationXref
id: REACT_155138
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_155138.3

SequenceSite2587
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2586
type: SequenceSite
position status: EQUAL
sequence position: 598

UnificationXref1290
type: UnificationXref
id: REACT_155607
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_155607.3

UnificationXref1295
type: UnificationXref
id: GO:0005788
db: GENE ONTOLOGY

UnificationXref1296
type: UnificationXref
id: 2024002
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2024002

UnificationXref1293
type: UnificationXref
id: 4199996
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199996

UnificationXref1294
type: UnificationXref
id: REACT_154252
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_154252.3

SequenceSite2580
type: SequenceSite
position status: EQUAL
sequence position: 164

SequenceSite2581
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2584
type: SequenceSite
position status: EQUAL
sequence position: 598

SequenceSite2585
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2582
type: SequenceSite
position status: EQUAL
sequence position: 598

SequenceSite2583
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1286
type: UnificationXref
id: REACT_151108
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_151108.1

UnificationXref1287
type: UnificationXref
id: 4197670
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197670

UnificationXref1288
type: UnificationXref
id: REACT_154778
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_154778.3

UnificationXref1289
type: UnificationXref
id: 4197754
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197754

inferred from electronic annotation
type: EvidenceCodeVocabulary
xref: UnificationXref26

SequenceSite2576
type: SequenceSite
position status: EQUAL
sequence position: 194

http://identifiers.org/pubmed/9809442
type: PublicationXref
id: 9809442
author: Marin-Garcia, J
author: Ananthakrishnan, R
author: Goldenthal, MJ
db: Pubmed
title: Cloning and molecular analysis of the human citrate synthase gene
source: Genome 41:733-738
year: 1998

SequenceSite2575
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite2578
type: SequenceSite
position status: EQUAL
sequence position: 194

UnificationXref1280
type: UnificationXref
id: 1629732
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1629732

SequenceSite2577
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref1281
type: UnificationXref
id: REACT_152401
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_152401.1

UnificationXref1282
type: UnificationXref
id: CHEBI:62924
db: ChEBI

SequenceSite2579
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1283
type: UnificationXref
id: 1629766
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1629766

UnificationXref1284
type: UnificationXref
id: REACT_151204
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_151204.1

UnificationXref1285
type: UnificationXref
id: 2023968
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2023968

SequenceSite2570
type: SequenceSite
position status: EQUAL
sequence position: 152

SequenceSite2571
type: SequenceSite
position status: EQUAL
sequence position: 34

SequenceSite2572
type: SequenceSite
position status: EQUAL
sequence position: 187

SequenceSite2573
type: SequenceSite
position status: EQUAL
sequence position: 34

SequenceSite2574
type: SequenceSite
position status: EQUAL
sequence position: 187

http://identifiers.org/pubmed/8662638
type: PublicationXref
id: 8662638
author: Wilson, MP
author: Majerus, PW
db: Pubmed
title: Isolation of inositol 1,3,4-trisphosphate 5/6-kinase, cDNA cloning and expression of the recombinant enzyme
source: J Biol Chem 271:11904-10
year: 1996

RNA Polymerase II Transcription Elongation
type: Pathway
data source: Provenance1
pathway component: REACT 156913.3
pathway component: REACT 29380.10
evidence: Evidence823
xref: UnificationXref9776
xref: RelationshipXref929
xref: UnificationXref9777
pathway order: PathwayStep814
pathway order: PathwayStep812
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Stromelysin-1
name: MMP3 fragment 55-99
name: MMP3_HUMAN
name: MMP3(55-99)
name: Matrix metalloproteinase-3
xref: UnificationXref15632
feature: FragmentFeature4785
cellular location: GO:0005576
comment: Reactome DB_ID: 4196419
display name: Q0WVU1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Stromelysin-1
name: MMP3 fragment 55-99
name: MMP3_HUMAN
name: MMP3(55-99)
name: Matrix metalloproteinase-3
xref: UnificationXref15631
feature: FragmentFeature4784
cellular location: GO:0005576
comment: Reactome DB_ID: 4196418
display name: Q84W77

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Stromelysin-1
name: MMP3 fragment 55-99
name: MMP3_HUMAN
name: MMP3(55-99)
name: Matrix metalloproteinase-3
xref: UnificationXref15630
feature: FragmentFeature4783
cellular location: GO:0005576
comment: Reactome DB_ID: 4196417
display name: Q5XF51

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Stromelysin-1
name: MMP3 fragment 55-99
name: MMP3_HUMAN
name: MMP3(55-99)
name: Matrix metalloproteinase-3
xref: UnificationXref15629
feature: FragmentFeature4782
cellular location: GO:0005576
comment: Reactome DB_ID: 4196416
display name: Q8LET7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: Stromelysin-1
name: MMP3 fragment 55-99
name: MMP3_HUMAN
name: MMP3(55-99)
name: Matrix metalloproteinase-3
xref: UnificationXref15628
feature: FragmentFeature4781
cellular location: GO:0005576
comment: Reactome DB_ID: 4196415
display name: O65340

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O23507
data source: Provenance1
name: Stromelysin-1
name: MMP3 fragment 55-99
name: MMP3_HUMAN
name: MMP3(55-99)
name: Matrix metalloproteinase-3
xref: UnificationXref15627
feature: FragmentFeature4780
cellular location: GO:0005576
comment: Reactome DB_ID: 4196414
display name: O23507

UniProt:P18616
type: ProteinReference
xref: UnificationXref9434
organism: Arabidopsis thaliana

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Stromelysin-1
name: MMP3 fragment 55-99
name: MMP3_HUMAN
name: MMP3(55-99)
name: Matrix metalloproteinase-3
xref: UnificationXref15626
feature: FragmentFeature4779
cellular location: GO:0005576
comment: Reactome DB_ID: 4196413
display name: Q9ZUJ5

Homologues of MMP3(55-99)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15636
cellular location: GO:0005576
comment: Reactome DB_ID: 4196423
comment: Converted from EntitySet in Reactome

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP3 intermediate form
name: Stromelysin-1
name: MMP3(55-477)
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15624
feature: FragmentFeature4778
cellular location: GO:0005576
comment: Reactome DB_ID: 4196147
display name: Q8GWW6

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP3 intermediate form
name: Stromelysin-1
name: MMP3(55-477)
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15623
feature: FragmentFeature4777
cellular location: GO:0005576
comment: Reactome DB_ID: 4196146
display name: O48680

http://identifiers.org/pubmed/642006
type: PublicationXref
id: 642006
author: Gall, JG
author: Blackburn, EH
db: Pubmed
title: A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena
source: J Mol Biol 120:33-53
year: 1978

SequenceSite2598
type: SequenceSite
position status: EQUAL
sequence position: 598

SequenceSite2597
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2599
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2593
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2594
type: SequenceSite
position status: EQUAL
sequence position: 598

SequenceSite2595
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2596
type: SequenceSite
position status: EQUAL
sequence position: 598

SequenceSite2590
type: SequenceSite
position status: EQUAL
sequence position: 598

SequenceSite2591
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2592
type: SequenceSite
position status: EQUAL
sequence position: 598

http://identifiers.org/pubmed/9438390
type: PublicationXref
id: 9438390
author: Webster, MK
author: Bardwell, WM
author: Meyer, AN
author: Donoghue, DJ
author: Robertson, SC
author: d'Avis, PY
db: Pubmed
title: Constitutive activation of fibroblast growth factor receptor 3 by mutations responsible for the lethal skeletal dysplasia thanatophoric dysplasia type I
source: Cell Growth Differ 9:71-8
year: 1998

UniProt:F4JML5
type: ProteinReference
xref: UnificationXref6106
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/9188485
type: PublicationXref
id: 9188485
author: Folk, JE
author: Park, MH
author: Wolff, EC
db: Pubmed
title: Enzyme-substrate intermediate formation at lysine 329 of human deoxyhypusine synthase
source: J Biol Chem 272:15865-71
year: 1997

7,8-dihydro-7-hydroxy-8S-glutathionylbenzo[a]pyrene
type: SmallMoleculeReference
name: 7,8-dihydro-7-hydroxy-8S-glutathionylbenzo[a]pyrene [ChEBI:34479]
name: 7,8-Dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene
xref: UnificationXref7179

IRS-related events
type: Pathway
data source: Provenance1
pathway component: REACT 81127.9
evidence: Evidence1182
xref: UnificationXref12586
xref: UnificationXref12587
pathway order: PathwayStep1163
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/7356336
type: PublicationXref
id: 7356336
author: Logue, EA
author: Fall, RR
author: Hector, ML
author: Cochran, BC
db: Pubmed
title: Subcellular localization of 3-methylcrotonyl-coenzyme A carboxylase in bovine kidney
source: Arch Biochem Biophys 199:28-36
year: 1980

UniProt:Q9ZNV4
type: ProteinReference
xref: UnificationXref5316
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/8541526
type: PublicationXref
id: 8541526
author: Park, JG
author: Hunter, S
author: Schreiber, AD
author: Indik, ZK
db: Pubmed
title: The molecular dissection of Fc gamma receptor mediated phagocytosis
source: Blood 86:4389-99
year: 1995

http://identifiers.org/pubmed/1371749
type: PublicationXref
id: 1371749
author: Saxty, BA
author: Groot, PH
author: Kmetz, PJ
author: Near, JC
author: Hughes, SA
author: Franklin, M
author: Wells, TN
author: Gloger, IS
author: Elshourbagy, NA
db: Pubmed
title: Cloning and expression of a human ATP-citrate lyase cDNA
source: Eur J Biochem 204:491-9
year: 1992

UniProt:Q9ZNW0
type: ProteinReference
xref: UnificationXref5805
organism: Arabidopsis thaliana

8,9-EpETrE [ChEBI:34490]
type: SmallMoleculeReference
name: 8,9-EpETrE
xref: UnificationXref3578

http://identifiers.org/pubmed/8631325
type: PublicationXref
id: 8631325
author: Peng, HL
author: Chao, YC
author: Chang, HY
author: Duggleby, RG
author: Huang, JG
db: Pubmed
title: Sequence differences between human muscle and liver cDNAs for UDPglucose pyrophosphorylase and kinetic properties of the recombinant enzymes expressed in Escherichia coli.
source: Eur J Biochem 235:173-9
year: 1996

UniProt:F4JMJ1
type: ProteinReference
xref: UnificationXref14872
organism: Arabidopsis thaliana

UnificationXref17260
type: UnificationXref
id: 4182459
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182459

UnificationXref17261
type: UnificationXref
id: 4182460
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182460

UnificationXref17262
type: UnificationXref
id: 4182461
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182461

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP10_HUMAN
name: Q8GWW6
name: Stromelysin-2
xref: UnificationXref15550
feature: FragmentFeature4718
cellular location: GO:0005576
comment: Reactome DB_ID: 4196043
display name: MMP10

Homologues of MMP11
type: Protein
data source: Provenance1
member physical entity: O23507
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q8LET7
xref: UnificationXref15562
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196055

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Stromelysin-3
name: Q9ZUJ5
name: MMP11_HUMAN
xref: UnificationXref15552
feature: FragmentFeature4719
cellular location: GO:0005576
comment: Reactome DB_ID: 4196045
display name: MMP11

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Stromelysin-3
name: MMP11_HUMAN
xref: UnificationXref15553
feature: FragmentFeature4720
cellular location: GO:0005576
comment: Reactome DB_ID: 4196046
display name: MMP11

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: Stromelysin-3
name: MMP11_HUMAN
name: O65340
xref: UnificationXref15554
feature: FragmentFeature4721
cellular location: GO:0005576
comment: Reactome DB_ID: 4196047
display name: MMP11

UniProt:Q9ZNT3
type: ProteinReference
xref: UnificationXref11747
organism: Arabidopsis thaliana

SequenceSite2507
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2506
type: SequenceSite
position status: EQUAL
sequence position: 196

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Stromelysin-3
name: MMP11_HUMAN
name: Q5XF51
xref: UnificationXref15556
feature: FragmentFeature4723
cellular location: GO:0005576
comment: Reactome DB_ID: 4196049
display name: MMP11

SequenceSite2509
type: SequenceSite
position status: EQUAL
sequence position: 1

UniProt:Q9ZNT0
type: ProteinReference
xref: UnificationXref7948
organism: Arabidopsis thaliana

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Stromelysin-3
name: MMP11_HUMAN
xref: UnificationXref15555
feature: FragmentFeature4722
cellular location: GO:0005576
comment: Reactome DB_ID: 4196048
display name: MMP11

SequenceSite2508
type: SequenceSite
position status: EQUAL
sequence position: 196

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Stromelysin-3
name: Q0WVU1
name: MMP11_HUMAN
xref: UnificationXref15558
feature: FragmentFeature4725
cellular location: GO:0005576
comment: Reactome DB_ID: 4196051
display name: MMP11

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Stromelysin-3
name: MMP11_HUMAN
name: Q84W77
xref: UnificationXref15557
feature: FragmentFeature4724
cellular location: GO:0005576
comment: Reactome DB_ID: 4196050
display name: MMP11

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: Stromelysin-3
name: MMP11_HUMAN
name: O48680
xref: UnificationXref15560
feature: FragmentFeature4727
cellular location: GO:0005576
comment: Reactome DB_ID: 4196053
display name: MMP11

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: Stromelysin-3
name: O04529
name: MMP11_HUMAN
xref: UnificationXref15559
feature: FragmentFeature4726
cellular location: GO:0005576
comment: Reactome DB_ID: 4196052
display name: MMP11

UnificationXref17264
type: UnificationXref
id: 4195462
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195462

UniProt:P24100
type: ProteinReference
xref: UnificationXref12156
organism: Arabidopsis thaliana

UnificationXref17263
type: UnificationXref
id: 4195460
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195460

http://identifiers.org/pubmed/19443651
type: PublicationXref
id: 19443651
author: Wang, Jianghai
author: Fukui, Lisa
author: Lee, Brian
author: Cai, Sheng
author: Chen, Yuan
author: Hu, Weidong
db: Pubmed
title: Conformational transition associated with E1-E2 interaction in small ubiquitin-like modifications
source: J. Biol. Chem. 284:20340-8
year: 2009

UnificationXref17266
type: UnificationXref
id: 4195466
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195466

SequenceSite2501
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17265
type: UnificationXref
id: REACT_155447
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_155447.3

SequenceSite2500
type: SequenceSite
position status: EQUAL
sequence position: 197

UnificationXref17268
type: UnificationXref
id: REACT_154745
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_154745.3

SequenceSite2503
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17267
type: UnificationXref
id: 4195468
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195468

SequenceSite2502
type: SequenceSite
position status: EQUAL
sequence position: 197

SequenceSite2505
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17269
type: UnificationXref
id: 4199942
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199942

SequenceSite2504
type: SequenceSite
position status: EQUAL
sequence position: 196

UnificationXref17250
type: UnificationXref
id: 4195456
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195456

UnificationXref17251
type: UnificationXref
id: 4195457
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195457

MMP2(30-660)
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Pro Matrix metalloproteinase-2
name: proMMP2
name: MMP2_HUMAN
xref: UnificationXref15566
feature: FragmentFeature4729
cellular location: GO:0005576
comment: Reactome DB_ID: 4196332
display name: Q9ZUJ5

MMP2(30-660)
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Pro Matrix metalloproteinase-2
name: proMMP2
name: MMP2_HUMAN
xref: UnificationXref15567
feature: FragmentFeature4730
cellular location: GO:0005576
comment: Reactome DB_ID: 4196333
display name: O23507

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Stromelysin-3
name: Q8GWW6
name: MMP11_HUMAN
xref: UnificationXref15561
feature: FragmentFeature4728
cellular location: GO:0005576
comment: Reactome DB_ID: 4196054
display name: MMP11

Homologues of MMP2(30-660)
type: Protein
data source: Provenance1
member physical entity: MMP2(30-660)
xref: UnificationXref15576
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196342

MMP2(30-660)
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Pro Matrix metalloproteinase-2
name: proMMP2
name: MMP2_HUMAN
xref: UnificationXref15570
feature: FragmentFeature4733
cellular location: GO:0005576
comment: Reactome DB_ID: 4196336
display name: Q5XF51

MMP2(30-660)
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Pro Matrix metalloproteinase-2
name: proMMP2
name: MMP2_HUMAN
xref: UnificationXref15569
feature: FragmentFeature4732
cellular location: GO:0005576
comment: Reactome DB_ID: 4196335
display name: Q8LET7

MMP2(30-660)
type: Protein
entity reference: O65340
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Pro Matrix metalloproteinase-2
name: proMMP2
name: MMP2_HUMAN
xref: UnificationXref15568
feature: FragmentFeature4731
cellular location: GO:0005576
comment: Reactome DB_ID: 4196334
display name: O65340

MMP2(30-660)
type: Protein
entity reference: O48680
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Pro Matrix metalloproteinase-2
name: proMMP2
name: MMP2_HUMAN
xref: UnificationXref15574
feature: FragmentFeature4737
cellular location: GO:0005576
comment: Reactome DB_ID: 4196340
display name: O48680

MMP2(30-660)
type: Protein
entity reference: O04529
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Pro Matrix metalloproteinase-2
name: proMMP2
name: MMP2_HUMAN
xref: UnificationXref15573
feature: FragmentFeature4736
cellular location: GO:0005576
comment: Reactome DB_ID: 4196339
display name: O04529

MMP2(30-660)
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Pro Matrix metalloproteinase-2
name: proMMP2
name: MMP2_HUMAN
xref: UnificationXref15572
feature: FragmentFeature4735
cellular location: GO:0005576
comment: Reactome DB_ID: 4196338
display name: Q0WVU1

http://identifiers.org/pubmed/19957260
type: PublicationXref
id: 19957260
author: Lambert, DM
author: Ferrer, JL
author: Bauvois, C
author: Wouters, J
author: Borel, F
author: Labar, G
db: Pubmed
title: Crystal structure of the human monoacylglycerol lipase, a key actor in endocannabinoid signaling
source: Chembiochem 11:218-27
year: 2010

MMP2(30-660)
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Pro Matrix metalloproteinase-2
name: proMMP2
name: MMP2_HUMAN
xref: UnificationXref15571
feature: FragmentFeature4734
cellular location: GO:0005576
comment: Reactome DB_ID: 4196337
display name: Q84W77

UnificationXref17255
type: UnificationXref
id: 4182451
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182451

UnificationXref17254
type: UnificationXref
id: 4182447
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182447

UnificationXref17253
type: UnificationXref
id: 4195459
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195459

UnificationXref17252
type: UnificationXref
id: 4195458
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195458

UnificationXref17259
type: UnificationXref
id: 4182458
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182458

UnificationXref17258
type: UnificationXref
id: 4182457
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182457

UnificationXref17257
type: UnificationXref
id: 4182456
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182456

UnificationXref17256
type: UnificationXref
id: 4182455
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182455

UnificationXref17240
type: UnificationXref
id: 4182481
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182481

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: O65340
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15532
feature: FragmentFeature4701
cellular location: GO:0005576
comment: Reactome DB_ID: 4196025
display name: MMP7

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15533
feature: FragmentFeature4702
cellular location: GO:0005576
comment: Reactome DB_ID: 4196026
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Q5XF51
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15534
feature: FragmentFeature4703
cellular location: GO:0005576
comment: Reactome DB_ID: 4196027
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Q8GWW6
name: Stromelysin-1
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15528
feature: FragmentFeature4698
cellular location: GO:0005576
comment: Reactome DB_ID: 4196021
display name: MMP3

Homologues of MMP7
type: Protein
data source: Provenance1
member physical entity: Q8LET7
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: O23507
xref: UnificationXref15540
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196033

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Q9ZUJ5
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15530
feature: FragmentFeature4699
cellular location: GO:0005576
comment: Reactome DB_ID: 4196023
display name: MMP7

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15531
feature: FragmentFeature4700
cellular location: GO:0005576
comment: Reactome DB_ID: 4196024
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Q0WVU1
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15536
feature: FragmentFeature4705
cellular location: GO:0005576
comment: Reactome DB_ID: 4196029
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Q84W77
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15535
feature: FragmentFeature4704
cellular location: GO:0005576
comment: Reactome DB_ID: 4196028
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP7_HUMAN
name: O48680
name: Matrilysin-1
xref: UnificationXref15538
feature: FragmentFeature4707
cellular location: GO:0005576
comment: Reactome DB_ID: 4196031
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: O04529
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15537
feature: FragmentFeature4706
cellular location: GO:0005576
comment: Reactome DB_ID: 4196030
display name: MMP7

SequenceSite2529
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17249
type: UnificationXref
id: 4182490
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182490

SequenceSite2528
type: SequenceSite
position status: EQUAL
sequence position: 35

UnificationXref17246
type: UnificationXref
id: 4182487
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182487

SequenceSite2525
type: SequenceSite
position status: EQUAL
sequence position: 2

ChEBI:28540 5beta-cholestane-3alpha,7alpha,26-triol
type: SmallMoleculeReference
name: 5beta-cholestane-3alpha,7alpha,26-triol
xref: UnificationXref2462

UnificationXref17245
type: UnificationXref
id: Q940C6
db: UniProt

SequenceSite2524
type: SequenceSite
position status: EQUAL
sequence position: 105

UnificationXref17248
type: UnificationXref
id: 4182489
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182489

SequenceSite2527
type: SequenceSite
position status: EQUAL
sequence position: 32

UnificationXref17247
type: UnificationXref
id: Q84JI6
db: UniProt

SequenceSite2526
type: SequenceSite
position status: EQUAL
sequence position: 105

UnificationXref17242
type: UnificationXref
id: 4182483
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182483

SequenceSite2521
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17241
type: UnificationXref
id: Q5QIT3
db: UniProt

SequenceSite2520
type: SequenceSite
position status: EQUAL
sequence position: 212

UnificationXref17244
type: UnificationXref
id: 4182485
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182485

SequenceSite2523
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17243
type: UnificationXref
id: F4I2K5
db: UniProt

SequenceSite2522
type: SequenceSite
position status: EQUAL
sequence position: 212

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP10_HUMAN
name: Stromelysin-2
name: O65340
xref: UnificationXref15543
feature: FragmentFeature4711
cellular location: GO:0005576
comment: Reactome DB_ID: 4196036
display name: MMP10

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP10_HUMAN
name: Stromelysin-2
xref: UnificationXref15544
feature: FragmentFeature4712
cellular location: GO:0005576
comment: Reactome DB_ID: 4196037
display name: MMP10

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP10_HUMAN
name: Q9ZUJ5
name: Stromelysin-2
xref: UnificationXref15541
feature: FragmentFeature4709
cellular location: GO:0005576
comment: Reactome DB_ID: 4196034
display name: MMP10

http://identifiers.org/pubmed/18555844
type: PublicationXref
id: 18555844
author: Buehrer, B
author: Madan, AK
author: Fain, JN
author: Bahouth, SW
author: Tichansky, DS
db: Pubmed
title: Comparison of messenger RNA distribution for 60 proteins in fat cells vs the nonfat cells of human omental adipose tissue
source: Metabolism 57:1005-15
year: 2008

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP10_HUMAN
name: Stromelysin-2
xref: UnificationXref15542
feature: FragmentFeature4710
cellular location: GO:0005576
comment: Reactome DB_ID: 4196035
display name: MMP10

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Q8GWW6
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15539
feature: FragmentFeature4708
cellular location: GO:0005576
comment: Reactome DB_ID: 4196032
display name: MMP7

Homologues of MMP10
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: O23507
member physical entity: Q8LET7
xref: UnificationXref15551
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196044

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP10_HUMAN
name: Stromelysin-2
name: O48680
xref: UnificationXref15549
feature: FragmentFeature4717
cellular location: GO:0005576
comment: Reactome DB_ID: 4196042
display name: MMP10

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP10_HUMAN
name: Stromelysin-2
name: O04529
xref: UnificationXref15548
feature: FragmentFeature4716
cellular location: GO:0005576
comment: Reactome DB_ID: 4196041
display name: MMP10

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP10_HUMAN
name: Stromelysin-2
name: Q0WVU1
xref: UnificationXref15547
feature: FragmentFeature4715
cellular location: GO:0005576
comment: Reactome DB_ID: 4196040
display name: MMP10

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP10_HUMAN
name: Stromelysin-2
name: Q84W77
xref: UnificationXref15546
feature: FragmentFeature4714
cellular location: GO:0005576
comment: Reactome DB_ID: 4196039
display name: MMP10

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP10_HUMAN
name: Stromelysin-2
name: Q5XF51
xref: UnificationXref15545
feature: FragmentFeature4713
cellular location: GO:0005576
comment: Reactome DB_ID: 4196038
display name: MMP10

SequenceSite2519
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17239
type: UnificationXref
id: Q9XGR4
db: UniProt

SequenceSite2518
type: SequenceSite
position status: EQUAL
sequence position: 212

UnificationXref17238
type: UnificationXref
id: 4182477
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182477

SequenceSite2517
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17237
type: UnificationXref
id: Q8VZQ4
db: UniProt

SequenceSite2516
type: SequenceSite
position status: EQUAL
sequence position: 212

5,6-EpETrE [ChEBI:34450]
type: SmallMoleculeReference
name: 5,6-EpETrE
xref: UnificationXref3575

UnificationXref17236
type: UnificationXref
id: 4182473
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182473

SequenceSite2515
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17235
type: UnificationXref
id: Q9ZWB6
db: UniProt

SequenceSite2514
type: SequenceSite
position status: EQUAL
sequence position: 212

UnificationXref17234
type: UnificationXref
id: 4182469
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182469

SequenceSite2513
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17233
type: UnificationXref
id: Q9SLI8
db: UniProt

SequenceSite2512
type: SequenceSite
position status: EQUAL
sequence position: 196

UnificationXref17232
type: UnificationXref
id: 4182465
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182465

SequenceSite2511
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17231
type: UnificationXref
id: Q56WJ0
db: UniProt

SequenceSite2510
type: SequenceSite
position status: EQUAL
sequence position: 196

UnificationXref17230
type: UnificationXref
id: 4182443
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182443

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP2 intermediate form
name: MMP2(67-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15597
feature: FragmentFeature4758
cellular location: GO:0005576
comment: Reactome DB_ID: 4195964
display name: Q8GWW6

SequenceSite2541
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2540
type: SequenceSite
position status: EQUAL
sequence position: 389

SequenceSite2542
type: SequenceSite
position status: EQUAL
sequence position: 389

SequenceSite2543
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite2544
type: SequenceSite
position status: EQUAL
sequence position: 105

SequenceSite2545
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite2546
type: SequenceSite
position status: EQUAL
sequence position: 105

SequenceSite2547
type: SequenceSite
position status: EQUAL
sequence position: 31

Homologues of MMP2(67-109)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15612
cellular location: GO:0005576
comment: Reactome DB_ID: 4195987
comment: Converted from EntitySet in Reactome

SequenceSite2548
type: SequenceSite
position status: EQUAL
sequence position: 34

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP2 fragment 67-109
name: MMP2(67-109)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15602
feature: FragmentFeature4759
cellular location: GO:0005576
comment: Reactome DB_ID: 4195977
display name: Q9ZUJ5

SequenceSite2549
type: SequenceSite
position status: EQUAL
sequence position: 2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O23507
data source: Provenance1
name: MMP2 fragment 67-109
name: MMP2(67-109)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15603
feature: FragmentFeature4760
cellular location: GO:0005576
comment: Reactome DB_ID: 4195978
display name: O23507

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP2 fragment 67-109
name: MMP2(67-109)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15604
feature: FragmentFeature4761
cellular location: GO:0005576
comment: Reactome DB_ID: 4195979
display name: O65340

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: MMP2 fragment 67-109
name: MMP2(67-109)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15605
feature: FragmentFeature4762
cellular location: GO:0005576
comment: Reactome DB_ID: 4195980
display name: Q8LET7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP2 fragment 67-109
name: MMP2(67-109)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15606
feature: FragmentFeature4763
cellular location: GO:0005576
comment: Reactome DB_ID: 4195981
display name: Q5XF51

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP2 fragment 67-109
name: MMP2(67-109)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15607
feature: FragmentFeature4764
cellular location: GO:0005576
comment: Reactome DB_ID: 4195982
display name: Q84W77

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP2 fragment 67-109
name: MMP2(67-109)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15608
feature: FragmentFeature4765
cellular location: GO:0005576
comment: Reactome DB_ID: 4195983
display name: Q0WVU1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP2 fragment 67-109
name: MMP2(67-109)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15609
feature: FragmentFeature4766
cellular location: GO:0005576
comment: Reactome DB_ID: 4195984
display name: O04529

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP2 fragment 67-109
name: MMP2(67-109)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15610
feature: FragmentFeature4767
cellular location: GO:0005576
comment: Reactome DB_ID: 4195985
display name: O48680

UnificationXref17291
type: UnificationXref
id: 4182494
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182494

UnificationXref17290
type: UnificationXref
id: REACT_2843
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2843.2

UnificationXref17295
type: UnificationXref
id: 4182491
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182491

SequenceSite2530
type: SequenceSite
position status: EQUAL
sequence position: 105

UnificationXref17294
type: UnificationXref
id: 4182429
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182429

UnificationXref17293
type: UnificationXref
id: 4182428
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182428

UnificationXref17292
type: UnificationXref
id: REACT_92203
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_92203.9

UnificationXref17298
type: UnificationXref
id: 4199573
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199573

SequenceSite2533
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17299
type: UnificationXref
id: REACT_84947
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_84947.9

SequenceSite2534
type: SequenceSite
position status: EQUAL
sequence position: 105

ChEBI:28533 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestanoyl-CoA
type: SmallMoleculeReference
name: 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestanoyl-CoA
xref: UnificationXref2399

UnificationXref17296
type: UnificationXref
id: 4182493
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182493

SequenceSite2531
type: SequenceSite
position status: EQUAL
sequence position: 32

UnificationXref17297
type: UnificationXref
id: REACT_155965
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_155965.3

SequenceSite2532
type: SequenceSite
position status: EQUAL
sequence position: 35

Homologues of MMP3(55-477)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15625
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196148

SequenceSite2537
type: SequenceSite
position status: EQUAL
sequence position: 1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP3 intermediate form
name: Stromelysin-1
name: MMP3(55-477)
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15615
feature: FragmentFeature4769
cellular location: GO:0005576
comment: Reactome DB_ID: 4196138
display name: Q9ZUJ5

SequenceSite2538
type: SequenceSite
position status: EQUAL
sequence position: 389

SequenceSite2535
type: SequenceSite
position status: EQUAL
sequence position: 1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP2 fragment 67-109
name: MMP2(67-109)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15611
feature: FragmentFeature4768
cellular location: GO:0005576
comment: Reactome DB_ID: 4195986
display name: Q8GWW6

SequenceSite2536
type: SequenceSite
position status: EQUAL
sequence position: 792

http://identifiers.org/pubmed/15538381
type: PublicationXref
id: 15538381
author: Lu, M
author: Gherzi, R
author: Leuenberger, SA
author: Hemmings, BA
author: Stoecklin, G
author: Hess, D
author: Mallaun, M
author: Schmidlin, M
author: Moroni, C
author: Gross, B
db: Pubmed
title: The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B
source: EMBO J 23:4760-9
year: 2004

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: MMP3 intermediate form
name: Stromelysin-1
name: MMP3(55-477)
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15618
feature: FragmentFeature4772
cellular location: GO:0005576
comment: Reactome DB_ID: 4196141
display name: Q8LET7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP3 intermediate form
name: Stromelysin-1
name: MMP3(55-477)
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15619
feature: FragmentFeature4773
cellular location: GO:0005576
comment: Reactome DB_ID: 4196142
display name: Q5XF51

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O23507
data source: Provenance1
name: MMP3 intermediate form
name: Stromelysin-1
name: MMP3(55-477)
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15616
feature: FragmentFeature4770
cellular location: GO:0005576
comment: Reactome DB_ID: 4196139
display name: O23507

SequenceSite2539
type: SequenceSite
position status: EQUAL
sequence position: 1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP3 intermediate form
name: Stromelysin-1
name: MMP3(55-477)
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15617
feature: FragmentFeature4771
cellular location: GO:0005576
comment: Reactome DB_ID: 4196140
display name: O65340

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP3 intermediate form
name: Stromelysin-1
name: MMP3(55-477)
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15622
feature: FragmentFeature4776
cellular location: GO:0005576
comment: Reactome DB_ID: 4196145
display name: O04529

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP3 intermediate form
name: Stromelysin-1
name: MMP3(55-477)
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15620
feature: FragmentFeature4774
cellular location: GO:0005576
comment: Reactome DB_ID: 4196143
display name: Q84W77

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP3 intermediate form
name: Stromelysin-1
name: MMP3(55-477)
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15621
feature: FragmentFeature4775
cellular location: GO:0005576
comment: Reactome DB_ID: 4196144
display name: Q0WVU1

Homologues of MMP2(30-66)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15587
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196353

MMP2(30-660)
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Pro Matrix metalloproteinase-2
name: proMMP2
name: MMP2_HUMAN
xref: UnificationXref15575
feature: FragmentFeature4738
cellular location: GO:0005576
comment: Reactome DB_ID: 4196341
display name: Q8GWW6

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP2(30-66)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: MMP2 fragment 30-66
xref: UnificationXref15577
feature: FragmentFeature4739
cellular location: GO:0005576
comment: Reactome DB_ID: 4196343
display name: Q9ZUJ5

UnificationXref17282
type: UnificationXref
id: 4192942
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192942

SequenceSite2561
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17281
type: UnificationXref
id: 4192941
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192941

SequenceSite2560
type: SequenceSite
position status: EQUAL
sequence position: 351

UnificationXref17284
type: UnificationXref
id: REACT_137272
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_137272.5

SequenceSite2563
type: SequenceSite
position status: EQUAL
sequence position: 44

UnificationXref17283
type: UnificationXref
id: 4192943
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192943

SequenceSite2562
type: SequenceSite
position status: EQUAL
sequence position: 351

Pyruvate metabolism and Citric Acid (TCA) cycle
type: Pathway
data source: Provenance1
pathway component: REACT 104471.9
pathway component: Interconversion of 2-oxoglutarate and 2-hydroxyglutarate
pathway component: REACT 85849.9
evidence: Evidence433
xref: UnificationXref4370
xref: RelationshipXref509
xref: UnificationXref4371
pathway order: PathwayStep421
pathway order: PathwayStep427
pathway order: PathwayStep430
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

UnificationXref17280
type: UnificationXref
id: 4192940
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192940

UnificationXref17289
type: UnificationXref
id: 113656
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113656

SequenceSite2568
type: SequenceSite
position status: EQUAL
sequence position: 152

SequenceSite2569
type: SequenceSite
position status: EQUAL
sequence position: 2

http://identifiers.org/pubmed/7635144
type: PublicationXref
id: 7635144
author: Squire, JA
author: Reck, F
author: Bendiak, B
author: Leong, P
author: Tan, J
author: D'Agostaro, AF
author: Schachter, H
author: Sarkar, M
db: Pubmed
title: The human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2- N-acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant protein
source: Eur J Biochem 231:317-28
year: 1995

UnificationXref17285
type: UnificationXref
id: 4199876
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199876

SequenceSite2564
type: SequenceSite
position status: EQUAL
sequence position: 522

UnificationXref17286
type: UnificationXref
id: REACT_146955
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_146955.5

SequenceSite2565
type: SequenceSite
position status: EQUAL
sequence position: 44

UnificationXref17287
type: UnificationXref
id: 113499
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113499

SequenceSite2566
type: SequenceSite
position status: EQUAL
sequence position: 522

UnificationXref17288
type: UnificationXref
id: REACT_3748
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3748.1

SequenceSite2567
type: SequenceSite
position status: EQUAL
sequence position: 2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP2(30-66)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: MMP2 fragment 30-66
xref: UnificationXref15582
feature: FragmentFeature4744
cellular location: GO:0005576
comment: Reactome DB_ID: 4196348
display name: Q84W77

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP2(30-66)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: MMP2 fragment 30-66
xref: UnificationXref15583
feature: FragmentFeature4745
cellular location: GO:0005576
comment: Reactome DB_ID: 4196349
display name: Q0WVU1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP2(30-66)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: MMP2 fragment 30-66
xref: UnificationXref15584
feature: FragmentFeature4746
cellular location: GO:0005576
comment: Reactome DB_ID: 4196350
display name: O04529

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP2(30-66)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: MMP2 fragment 30-66
xref: UnificationXref15585
feature: FragmentFeature4747
cellular location: GO:0005576
comment: Reactome DB_ID: 4196351
display name: O48680

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O23507
data source: Provenance1
name: MMP2(30-66)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: MMP2 fragment 30-66
xref: UnificationXref15578
feature: FragmentFeature4740
cellular location: GO:0005576
comment: Reactome DB_ID: 4196344
display name: O23507

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP2(30-66)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: MMP2 fragment 30-66
xref: UnificationXref15579
feature: FragmentFeature4741
cellular location: GO:0005576
comment: Reactome DB_ID: 4196345
display name: O65340

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: MMP2(30-66)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: MMP2 fragment 30-66
xref: UnificationXref15580
feature: FragmentFeature4742
cellular location: GO:0005576
comment: Reactome DB_ID: 4196346
display name: Q8LET7

http://identifiers.org/pubmed/11907280
type: PublicationXref
id: 11907280
author: Hagting, A
author: Pines, J
author: Jackman, M
author: Kubota, Y
author: Den Elzen, N
db: Pubmed
title: Cyclin A- and cyclin E-Cdk complexes shuttle between the nucleus and the cytoplasm
source: Mol Biol Cell 13:1030-45
year: 2002

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP2(30-66)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: MMP2 fragment 30-66
xref: UnificationXref15581
feature: FragmentFeature4743
cellular location: GO:0005576
comment: Reactome DB_ID: 4196347
display name: Q5XF51

http://identifiers.org/pubmed/10448521
type: PublicationXref
id: 10448521
author: Seetharam, B
db: Pubmed
title: Receptor-mediated endocytosis of cobalamin (vitamin B12)
source: Annu. Rev. Nutr. 19:173-95
year: 1999

Homologues of MMP2(67-660)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15598
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4195965

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP2(30-66)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: MMP2 fragment 30-66
xref: UnificationXref15586
feature: FragmentFeature4748
cellular location: GO:0005576
comment: Reactome DB_ID: 4196352
display name: Q8GWW6

UnificationXref17273
type: UnificationXref
id: 4192933
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192933

SequenceSite2552
type: SequenceSite
position status: EQUAL
sequence position: 34

UnificationXref17272
type: UnificationXref
id: REACT_156508
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_156508.3

SequenceSite2551
type: SequenceSite
position status: EQUAL
sequence position: 31

http://identifiers.org/pubmed/9335335
type: PublicationXref
id: 9335335
author: Bell, SP
author: Aparicio, OM
author: Weinstein, DM
db: Pubmed
title: Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase.
source: Cell 91:59-69
year: 1997

UnificationXref17271
type: UnificationXref
id: 4199943
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199943

SequenceSite2550
type: SequenceSite
position status: EQUAL
sequence position: 105

UnificationXref17270
type: UnificationXref
id: REACT_157187
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_157187.3

SequenceSite2559
type: SequenceSite
position status: EQUAL
sequence position: 1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP2 intermediate form
name: MMP2(67-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15588
feature: FragmentFeature4749
cellular location: GO:0005576
comment: Reactome DB_ID: 4195938
display name: Q9ZUJ5

UnificationXref17278
type: UnificationXref
id: 4192938
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192938

SequenceSite2557
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17279
type: UnificationXref
id: 4192939
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192939

SequenceSite2558
type: SequenceSite
position status: EQUAL
sequence position: 351

UnificationXref17276
type: UnificationXref
id: 4192936
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192936

SequenceSite2555
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17277
type: UnificationXref
id: 4192937
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192937

SequenceSite2556
type: SequenceSite
position status: EQUAL
sequence position: 792

UnificationXref17274
type: UnificationXref
id: 4192934
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192934

SequenceSite2553
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17275
type: UnificationXref
id: 4192935
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192935

SequenceSite2554
type: SequenceSite
position status: EQUAL
sequence position: 105

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP2 intermediate form
name: MMP2(67-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15595
feature: FragmentFeature4756
cellular location: GO:0005576
comment: Reactome DB_ID: 4195960
display name: O04529

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP2 intermediate form
name: MMP2(67-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15596
feature: FragmentFeature4757
cellular location: GO:0005576
comment: Reactome DB_ID: 4195962
display name: O48680

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP2 intermediate form
name: MMP2(67-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15593
feature: FragmentFeature4754
cellular location: GO:0005576
comment: Reactome DB_ID: 4195954
display name: Q84W77

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP2 intermediate form
name: MMP2(67-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15594
feature: FragmentFeature4755
cellular location: GO:0005576
comment: Reactome DB_ID: 4195958
display name: Q0WVU1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: MMP2 intermediate form
name: MMP2(67-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15591
feature: FragmentFeature4752
cellular location: GO:0005576
comment: Reactome DB_ID: 4195948
display name: Q8LET7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP2 intermediate form
name: MMP2(67-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15592
feature: FragmentFeature4753
cellular location: GO:0005576
comment: Reactome DB_ID: 4195952
display name: Q5XF51

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O23507
data source: Provenance1
name: MMP2 intermediate form
name: MMP2(67-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15589
feature: FragmentFeature4750
cellular location: GO:0005576
comment: Reactome DB_ID: 4195942
display name: O23507

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP2 intermediate form
name: MMP2(67-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
xref: UnificationXref15590
feature: FragmentFeature4751
cellular location: GO:0005576
comment: Reactome DB_ID: 4195946
display name: O65340

D-Fructose 2,6-bisphosphate [ChEBI:28602]
type: SmallMoleculeReference
name: D-Fructose 2,6-bisphosphate
xref: UnificationXref204

http://identifiers.org/pubmed/9712840
type: PublicationXref
id: 9712840
author: Kikuchi, Y
author: Mizutani, M
author: Katada, T
author: Imai, M
author: Hoshino, S
author: Hanaoka, F
author: Ui, M
db: Pubmed
title: Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1.
source: J Biol Chem 273:22254-9
year: 1998

http://identifiers.org/pubmed/15534001
type: PublicationXref
id: 15534001
author: Allison, JG
author: Williams, CC
author: Beckman, BS
author: Jones, FE
author: Vidal, GA
author: Burow, ME
author: Marrero, L
db: Pubmed
title: The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone
source: J Cell Biol 167:469-78
year: 2004

http://identifiers.org/pubmed/12445824
type: PublicationXref
id: 12445824
author: Ganapathy, V
author: Inoue, K
author: Zhuang, L
db: Pubmed
title: Human Na+ -coupled citrate transporter: primary structure, genomic organization, and transport function
source: Biochem Biophys Res Commun 299:465-71
year: 2002

UnificationXref17212
type: UnificationXref
id: 4199594
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199594

UnificationXref17213
type: UnificationXref
id: REACT_84460
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_84460.9

UnificationXref17214
type: UnificationXref
id: 4195455
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195455

UnificationXref17215
type: UnificationXref
id: 4183975
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183975

UnificationXref17210
type: UnificationXref
id: 4199593
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199593

UnificationXref17211
type: UnificationXref
id: REACT_99771
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_99771.9

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP7(18-94)
name: MMP7 fragment 18-94
name: Q84W77
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15655
feature: FragmentFeature4804
cellular location: GO:0005576
comment: Reactome DB_ID: 4196119
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Q0WVU1
name: MMP7(18-94)
name: MMP7 fragment 18-94
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15656
feature: FragmentFeature4805
cellular location: GO:0005576
comment: Reactome DB_ID: 4196120
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: O04529
name: MMP7(18-94)
name: MMP7 fragment 18-94
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15657
feature: FragmentFeature4806
cellular location: GO:0005576
comment: Reactome DB_ID: 4196121
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP7(18-94)
name: MMP7 fragment 18-94
name: MMP7_HUMAN
name: O48680
name: Matrilysin-1
xref: UnificationXref15658
feature: FragmentFeature4807
cellular location: GO:0005576
comment: Reactome DB_ID: 4196122
display name: MMP7

UnificationXref17216
type: UnificationXref
id: 4195471
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195471

UnificationXref17217
type: UnificationXref
id: 4195472
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195472

UnificationXref17218
type: UnificationXref
id: REACT_143769
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_143769.5

UnificationXref17219
type: UnificationXref
id: 4195467
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195467

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP7(18-94)
name: MMP7 fragment 18-94
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15653
feature: FragmentFeature4802
cellular location: GO:0005576
comment: Reactome DB_ID: 4196117
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP7(18-94)
name: O65340
name: MMP7 fragment 18-94
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15652
feature: FragmentFeature4801
cellular location: GO:0005576
comment: Reactome DB_ID: 4196116
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP7(18-94)
name: Q5XF51
name: MMP7 fragment 18-94
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15654
feature: FragmentFeature4803
cellular location: GO:0005576
comment: Reactome DB_ID: 4196118
display name: MMP7

Homologues of MMP7(18-94)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: O23507
member physical entity: Q8LET7
xref: UnificationXref15660
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196124

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: proMMP7
name: Q8GWW6
name: MMP7(18-267)
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15648
feature: FragmentFeature4798
cellular location: GO:0005576
comment: Reactome DB_ID: 4196112
display name: MMP7

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP7(18-94)
name: MMP7 fragment 18-94
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15651
feature: FragmentFeature4800
cellular location: GO:0005576
comment: Reactome DB_ID: 4196115
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Q9ZUJ5
name: MMP7(18-94)
name: MMP7 fragment 18-94
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15650
feature: FragmentFeature4799
cellular location: GO:0005576
comment: Reactome DB_ID: 4196114
display name: MMP7

UnificationXref17225
type: UnificationXref
id: 4195454
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195454

UnificationXref17226
type: UnificationXref
id: 4182433
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182433

UnificationXref17223
type: UnificationXref
id: 4199944
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199944

UnificationXref17224
type: UnificationXref
id: REACT_144870
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_144870.5

UnificationXref17221
type: UnificationXref
id: 4195470
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195470

UnificationXref17222
type: UnificationXref
id: REACT_139756
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_139756.5

UnificationXref17220
type: UnificationXref
id: 4195469
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4195469

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: proMMP7
name: MMP7(18-267)
name: O04529
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15646
feature: FragmentFeature4796
cellular location: GO:0005576
comment: Reactome DB_ID: 4196110
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: proMMP7
name: MMP7(18-267)
name: MMP7_HUMAN
name: O48680
name: Matrilysin-1
xref: UnificationXref15647
feature: FragmentFeature4797
cellular location: GO:0005576
comment: Reactome DB_ID: 4196111
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: proMMP7
name: MMP7(18-267)
name: Q0WVU1
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15645
feature: FragmentFeature4795
cellular location: GO:0005576
comment: Reactome DB_ID: 4196109
display name: MMP7

UnificationXref17229
type: UnificationXref
id: 4182442
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182442

UnificationXref17227
type: UnificationXref
id: 4182437
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182437

UnificationXref17228
type: UnificationXref
id: 4182441
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182441

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: proMMP7
name: MMP7(18-267)
name: Q84W77
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15644
feature: FragmentFeature4794
cellular location: GO:0005576
comment: Reactome DB_ID: 4196108
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: proMMP7
name: MMP7(18-267)
name: Q5XF51
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15643
feature: FragmentFeature4793
cellular location: GO:0005576
comment: Reactome DB_ID: 4196107
display name: MMP7

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: proMMP7
name: MMP7(18-267)
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15642
feature: FragmentFeature4792
cellular location: GO:0005576
comment: Reactome DB_ID: 4196106
display name: MMP7

http://identifiers.org/pubmed/7317031
type: PublicationXref
id: 7317031
author: Orford, C R
author: Scott, J E
db: Pubmed
title: Dermatan sulphate-rich proteoglycan associates with rat tail-tendon collagen at the d band in the gap region
source: Biochem. J. 197:213-6
year: 1981

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: proMMP7
name: MMP7(18-267)
name: O65340
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15641
feature: FragmentFeature4791
cellular location: GO:0005576
comment: Reactome DB_ID: 4196105
display name: MMP7

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: proMMP7
name: MMP7(18-267)
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15640
feature: FragmentFeature4790
cellular location: GO:0005576
comment: Reactome DB_ID: 4196104
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: proMMP7
name: Q9ZUJ5
name: MMP7(18-267)
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15639
feature: FragmentFeature4789
cellular location: GO:0005576
comment: Reactome DB_ID: 4196103
display name: MMP7

Homologues of MMP7(18-267)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: O23507
member physical entity: Q8LET7
xref: UnificationXref15649
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196113

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Stromelysin-1
name: MMP3 fragment 55-99
name: MMP3_HUMAN
name: MMP3(55-99)
name: Matrix metalloproteinase-3
xref: UnificationXref15635
feature: FragmentFeature4788
cellular location: GO:0005576
comment: Reactome DB_ID: 4196422
display name: Q8GWW6

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q2V4B9
data source: Provenance1
name: Glucose transporter type 2, liver
name: SLC2A2
name: Q2V4B9
name: Solute carrier family 2, facilitated glucose transporter, member 2
xref: UnificationXref60
feature: FragmentFeature11
cellular location: GO:0005886
comment: Reactome DB_ID: 4176853
display name: GLUT2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FYG3
data source: Provenance1
name: Glucose transporter type 2, liver
name: Q9FYG3
name: SLC2A2
name: Solute carrier family 2, facilitated glucose transporter, member 2
xref: UnificationXref59
feature: FragmentFeature10
cellular location: GO:0005886
comment: Reactome DB_ID: 4176852
display name: GLUT2

Q0WVE9
type: Protein
entity reference: Q0WVE9
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Glucose transporter type 2, liver
name: SLC2A2
name: Solute carrier family 2, facilitated glucose transporter, member 2
xref: UnificationXref58
feature: FragmentFeature9
cellular location: GO:0005886
comment: Reactome DB_ID: 4176851
display name: GLUT2

Homologues of SLC2A2
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q0WVE9
xref: UnificationXref62
cellular location: GO:0005886
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4176855

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q56ZZ7
data source: Provenance1
name: SLC2A5
name: Q56ZZ7
name: Solute carrier family 2, facilitated glucose transporter member 5
xref: UnificationXref43
feature: FragmentFeature8
cellular location: GO:0005886
comment: Reactome DB_ID: 4184416
display name: GLUT5

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q56ZZ7
data source: Provenance1
name: Glucose transporter type 2, liver
name: SLC2A2
name: Q56ZZ7
name: Solute carrier family 2, facilitated glucose transporter, member 2
xref: UnificationXref61
feature: FragmentFeature12
cellular location: GO:0005886
comment: Reactome DB_ID: 4176854
display name: GLUT2

Homologues of SLC2A1
type: Protein
data source: Provenance1
member physical entity: Q0WVE9
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref70
cellular location: GO:0005886
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4176849

Q0WVE9
type: Protein
entity reference: Q0WVE9
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Solute carrier family 2, facilitated glucose transporter, member 1
name: Glucose transporter type 1, erythrocyte/brain
name: SLC2A1
name: HepG2 glucose transporter
xref: UnificationXref66
feature: FragmentFeature13
cellular location: GO:0005886
comment: Reactome DB_ID: 4176836
display name: GLUT1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FYG3
data source: Provenance1
name: Q9FYG3
name: Solute carrier family 2, facilitated glucose transporter, member 1
name: Glucose transporter type 1, erythrocyte/brain
name: SLC2A1
name: HepG2 glucose transporter
xref: UnificationXref67
feature: FragmentFeature14
cellular location: GO:0005886
comment: Reactome DB_ID: 4176840
display name: GLUT1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q2V4B9
data source: Provenance1
name: Solute carrier family 2, facilitated glucose transporter, member 1
name: Glucose transporter type 1, erythrocyte/brain
name: SLC2A1
name: Q2V4B9
name: HepG2 glucose transporter
xref: UnificationXref68
feature: FragmentFeature15
cellular location: GO:0005886
comment: Reactome DB_ID: 4176844
display name: GLUT1

UnificationXref1300
type: UnificationXref
id: 2024016
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2024016

UnificationXref1302
type: UnificationXref
id: 113551
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113551

UnificationXref1301
type: UnificationXref
id: REACT_150490
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_150490.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: Stromelysin-1
name: MMP3 fragment 55-99
name: MMP3_HUMAN
name: MMP3(55-99)
name: Matrix metalloproteinase-3
xref: UnificationXref15633
feature: FragmentFeature4786
cellular location: GO:0005576
comment: Reactome DB_ID: 4196420
display name: O04529

UnificationXref1304
type: UnificationXref
id: Q941B2
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: Stromelysin-1
name: MMP3 fragment 55-99
name: MMP3_HUMAN
name: MMP3(55-99)
name: Matrix metalloproteinase-3
xref: UnificationXref15634
feature: FragmentFeature4787
cellular location: GO:0005576
comment: Reactome DB_ID: 4196421
display name: O48680

UnificationXref1303
type: UnificationXref
id: REACT_3382
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3382.2

Homologues of SLC2A3
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q0WVE9
xref: UnificationXref76
cellular location: GO:0005886
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4176861

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q56ZZ7
data source: Provenance1
name: Solute carrier family 2, facilitated glucose transporter, member 1
name: Glucose transporter type 1, erythrocyte/brain
name: Q56ZZ7
name: SLC2A1
name: HepG2 glucose transporter
xref: UnificationXref69
feature: FragmentFeature16
cellular location: GO:0005886
comment: Reactome DB_ID: 4176848
display name: GLUT1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FYG3
data source: Provenance1
name: Q9FYG3
name: Glucose transporter type 3, brain
name: SLC2A3
name: Solute carrier family 2, facilitated glucose transporter, member 3
xref: UnificationXref73
feature: FragmentFeature18
cellular location: GO:0005886
comment: Reactome DB_ID: 4176858
display name: GLUT3

Q0WVE9
type: Protein
entity reference: Q0WVE9
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Glucose transporter type 3, brain
name: SLC2A3
name: Solute carrier family 2, facilitated glucose transporter, member 3
xref: UnificationXref72
feature: FragmentFeature17
cellular location: GO:0005886
comment: Reactome DB_ID: 4176857
display name: GLUT3

http://identifiers.org/pubmed/12474143
type: PublicationXref
id: 12474143
author: Carlson, Christopher G
author: Hoffbuhr, Kristen C
author: Kennaway, Nancy G
author: Glerum, D Moira
author: Antonicka, Hana
author: Leary, Scot C
author: Shoubridge, EA
author: Mattman, Andre
db: Pubmed
title: Mutations in COX15 produce a defect in the mitochondrial heme biosynthetic pathway, causing early-onset fatal hypertrophic cardiomyopathy
source: Am. J. Hum. Genet. 72:101-14
year: 2003

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q56ZZ7
data source: Provenance1
name: Glucose transporter type 3, brain
name: SLC2A3
name: Q56ZZ7
name: Solute carrier family 2, facilitated glucose transporter, member 3
xref: UnificationXref75
feature: FragmentFeature20
cellular location: GO:0005886
comment: Reactome DB_ID: 4176860
display name: GLUT3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q2V4B9
data source: Provenance1
name: Glucose transporter type 3, brain
name: SLC2A3
name: Q2V4B9
name: Solute carrier family 2, facilitated glucose transporter, member 3
xref: UnificationXref74
feature: FragmentFeature19
cellular location: GO:0005886
comment: Reactome DB_ID: 4176859
display name: GLUT3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FYG3
data source: Provenance1
name: Q9FYG3
name: SLC2A4
name: Glucose transporter type 4, insulin-responsive
name: Solute carrier family 2, facilitated glucose transporter, member 4
xref: UnificationXref79
feature: FragmentFeature22
cellular location: GO:0005886
comment: Reactome DB_ID: 4176864
display name: GLUT4

UnificationXref17200
type: UnificationXref
id: 4182743
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182743

SequenceSite2600
type: SequenceSite
position status: EQUAL
sequence position: 598

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q2V4B9
data source: Provenance1
name: SLC2A4
name: Q2V4B9
name: Glucose transporter type 4, insulin-responsive
name: Solute carrier family 2, facilitated glucose transporter, member 4
xref: UnificationXref80
feature: FragmentFeature23
cellular location: GO:0005886
comment: Reactome DB_ID: 4176865
display name: GLUT4

Homologues of SLC2A4
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q0WVE9
xref: UnificationXref82
cellular location: GO:0005886
comment: Reactome DB_ID: 4176867
comment: Converted from EntitySet in Reactome

Q0WVE9
type: Protein
entity reference: Q0WVE9
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: SLC2A4
name: Glucose transporter type 4, insulin-responsive
name: Solute carrier family 2, facilitated glucose transporter, member 4
xref: UnificationXref78
feature: FragmentFeature21
cellular location: GO:0005886
comment: Reactome DB_ID: 4176863
display name: GLUT4

UnificationXref17203
type: UnificationXref
id: REACT_83047
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_83047.9

SequenceSite2603
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17204
type: UnificationXref
id: 4182765
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182765

SequenceSite2604
type: SequenceSite
position status: EQUAL
sequence position: 598

UnificationXref17201
type: UnificationXref
id: REACT_90785
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_90785.9

SequenceSite2601
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17202
type: UnificationXref
id: 4182742
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182742

SequenceSite2602
type: SequenceSite
position status: EQUAL
sequence position: 598

UnificationXref17207
type: UnificationXref
id: REACT_105715
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_105715.9

SequenceSite2607
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1311
type: UnificationXref
id: 2024008
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2024008

UnificationXref17208
type: UnificationXref
id: 4199592
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199592

SequenceSite2608
type: SequenceSite
position status: EQUAL
sequence position: 650

UnificationXref1310
type: UnificationXref
id: REACT_155221
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_155221.3

UnificationXref17205
type: UnificationXref
id: REACT_94546
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_94546.9

SequenceSite2605
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17206
type: UnificationXref
id: 4199591
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199591

SequenceSite2606
type: SequenceSite
position status: EQUAL
sequence position: 650

UnificationXref1315
type: UnificationXref
id: 4197619
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197619

UnificationXref1314
type: UnificationXref
id: REACT_151651
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_151651.1

UnificationXref17209
type: UnificationXref
id: REACT_80342
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_80342.9

SequenceSite2609
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1313
type: UnificationXref
id: 2024012
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2024012

UnificationXref1312
type: UnificationXref
id: REACT_152017
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_152017.1

UnificationXref1307
type: UnificationXref
id: 4197616
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197616

UnificationXref1308
type: UnificationXref
id: 4197617
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197617

UnificationXref1305
type: UnificationXref
id: 4197614
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197614

UnificationXref1306
type: UnificationXref
id: Q9ASV3
db: UniProt

UnificationXref1309
type: UnificationXref
id: 4197760
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197760

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: P93834
data source: Provenance1
name: glucokinase
name: P93834
xref: UnificationXref106
feature: FragmentFeature25
cellular location: GO:0005829
comment: Reactome DB_ID: 4176875
display name: GCK

Homologues of GCK
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q9FZG4
member physical entity: Q9T071
xref: UnificationXref117
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4176896

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q56ZZ7
data source: Provenance1
name: SLC2A4
name: Q56ZZ7
name: Glucose transporter type 4, insulin-responsive
name: Solute carrier family 2, facilitated glucose transporter, member 4
xref: UnificationXref81
feature: FragmentFeature24
cellular location: GO:0005886
comment: Reactome DB_ID: 4176866
display name: GLUT4

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q42525
data source: Provenance1
name: glucokinase
name: Q42525
xref: UnificationXref114
feature: FragmentFeature29
cellular location: GO:0005829
comment: Reactome DB_ID: 4176891
display name: GCK

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LPS1
data source: Provenance1
name: glucokinase
name: Q9LPS1
xref: UnificationXref112
feature: FragmentFeature28
cellular location: GO:0005829
comment: Reactome DB_ID: 4176887
display name: GCK

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q56XE8
data source: Provenance1
name: glucokinase
name: Q56XE8
xref: UnificationXref110
feature: FragmentFeature27
cellular location: GO:0005829
comment: Reactome DB_ID: 4176883
display name: GCK

Q9FZG4
type: Protein
entity reference: Q9FZG4
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: glucokinase
xref: UnificationXref108
feature: FragmentFeature26
cellular location: GO:0005829
comment: Reactome DB_ID: 4176879
display name: GCK

Stoichiometry2039
type: Stoichiometry
physical entity: PhysicalEntity310
stoichiometric coefficient: 1.0

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: P93834
data source: Provenance1
name: HK III
name: HXK3_HUMAN
name: Hexokinase type III
name: hexokinase leukocyte form
name: hexokinase 3
name: P93834
name: hexokinase type 3
xref: UnificationXref125
feature: FragmentFeature37
cellular location: GO:0005829
comment: Reactome DB_ID: 4176904
display name: HK3

Q9FZG4
type: Protein
entity reference: Q9FZG4
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: HK III
name: HXK3_HUMAN
name: Hexokinase type III
name: hexokinase leukocyte form
name: hexokinase 3
name: hexokinase type 3
xref: UnificationXref126
feature: FragmentFeature38
cellular location: GO:0005829
comment: Reactome DB_ID: 4176905
display name: HK3

Stoichiometry2037
type: Stoichiometry
physical entity: Homologues of KHSRP(1-710)
stoichiometric coefficient: 1.0

Q9T071
type: Protein
entity reference: Q9T071
data source: Provenance1
name: HK I
name: Note: the coordinates are copied over from Homo sapiens.
name: Hexokinase, type I
name: Brain form hexokinase
name: hexokinase 1
name: HXK1_HUMAN
name: hexokinase brain form
name: hexokinase type 1
xref: UnificationXref123
feature: FragmentFeature36
cellular location: GO:0005829
comment: Reactome DB_ID: 4176902
display name: HK1

Stoichiometry2038
type: Stoichiometry
physical entity: PhysicalEntity309
stoichiometric coefficient: 1.0

Homologues of HK3
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q9FZG4
member physical entity: Q9T071
xref: UnificationXref131
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4176910

HK I
type: Protein
entity reference: Q9LPS1
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Hexokinase, type I
name: Brain form hexokinase
name: Q9LPS1
name: hexokinase 1
name: HXK1_HUMAN
name: hexokinase brain form
name: hexokinase type 1
xref: UnificationXref121
feature: FragmentFeature34
cellular location: GO:0005829
comment: Reactome DB_ID: 4176900
display name: HK1

HK I
type: Protein
entity reference: Q42525
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Hexokinase, type I
name: Brain form hexokinase
name: Q42525
name: hexokinase 1
name: HXK1_HUMAN
name: hexokinase brain form
name: hexokinase type 1
xref: UnificationXref122
feature: FragmentFeature35
cellular location: GO:0005829
comment: Reactome DB_ID: 4176901
display name: HK1

HK I
type: Protein
entity reference: Q9FZG4
data source: Provenance1
name: Q9FZG4
name: Note: the coordinates are copied over from Homo sapiens.
name: Hexokinase, type I
name: Brain form hexokinase
name: hexokinase 1
name: HXK1_HUMAN
name: hexokinase brain form
name: hexokinase type 1
xref: UnificationXref119
feature: FragmentFeature32
cellular location: GO:0005829
comment: Reactome DB_ID: 4176898
display name: HK1

HK I
type: Protein
entity reference: Q56XE8
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Hexokinase, type I
name: Brain form hexokinase
name: Q56XE8
name: hexokinase 1
name: HXK1_HUMAN
name: hexokinase brain form
name: hexokinase type 1
xref: UnificationXref120
feature: FragmentFeature33
cellular location: GO:0005829
comment: Reactome DB_ID: 4176899
display name: HK1

http://identifiers.org/pubmed/18173545
type: PublicationXref
id: 18173545
author: Calamita, G
author: Svelto, M
author: Portincasa, P
author: Palasciano, G
db: Pubmed
title: Aquaporins in the hepatobiliary tract. Which, where and what they do in health and disease
source: Eur J Clin Invest 38:1-10
year: 2008

Stoichiometry2031
type: Stoichiometry
physical entity: Complex742
stoichiometric coefficient: 1.0

Stoichiometry2032
type: Stoichiometry
physical entity: PhysicalEntity307
stoichiometric coefficient: 1.0

Stoichiometry2030
type: Stoichiometry
physical entity: PhysicalEntity306
stoichiometric coefficient: 4.0

Stoichiometry2035
type: Stoichiometry
physical entity: PhysicalEntity308
stoichiometric coefficient: 1.0

UnificationXref1319
type: UnificationXref
id: CHEBI:16507
db: ChEBI

Stoichiometry2036
type: Stoichiometry
physical entity: Homologues of TNPO1
stoichiometric coefficient: 1.0

UnificationXref1318
type: UnificationXref
id: REACT_152369
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_152369.1

Stoichiometry2033
type: Stoichiometry
physical entity: Homologues of ZFP36L1
stoichiometric coefficient: 1.0

UnificationXref1317
type: UnificationXref
id: 2024018
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2024018

Stoichiometry2034
type: Stoichiometry
physical entity: Homologues of ZFP36
stoichiometric coefficient: 1.0

UnificationXref1316
type: UnificationXref
id: REACT_156616
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_156616.3

UnificationXref1325
type: UnificationXref
id: REACT_159703
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_159703.3

UnificationXref1326
type: UnificationXref
id: CHEBI:18384
db: ChEBI

UnificationXref1323
type: UnificationXref
id: REACT_153581
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_153581.3

UnificationXref1324
type: UnificationXref
id: 4199998
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199998

UnificationXref1321
type: UnificationXref
id: REACT_152284
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_152284.1

UnificationXref1322
type: UnificationXref
id: 4197850
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197850

UnificationXref1320
type: UnificationXref
id: 2564836
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2564836

HK I
type: Protein
entity reference: P93834
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Hexokinase, type I
name: Brain form hexokinase
name: hexokinase 1
name: HXK1_HUMAN
name: hexokinase brain form
name: hexokinase type 1
name: P93834
xref: UnificationXref118
feature: FragmentFeature31
cellular location: GO:0005829
comment: Reactome DB_ID: 4176897
display name: HK1

Homologues of HK1
type: Protein
data source: Provenance1
member physical entity: HK I
member physical entity: Q9T071
xref: UnificationXref124
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4176903

Q9T071
type: Protein
entity reference: Q9T071
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: glucokinase
xref: UnificationXref116
feature: FragmentFeature30
cellular location: GO:0005829
comment: Reactome DB_ID: 4176895
display name: GCK

Stoichiometry2048
type: Stoichiometry
physical entity: Complex750
stoichiometric coefficient: 1.0

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q56XE8
data source: Provenance1
name: glucokinase
name: Q56XE8
xref: UnificationXref138
feature: FragmentFeature45
cellular location: GO:0005654
comment: Reactome DB_ID: 4183622
display name: GCK

Stoichiometry2049
type: Stoichiometry
physical entity: Note: the coordinates are copied over from Homo sapiens.
stoichiometric coefficient: 1.0

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LPS1
data source: Provenance1
name: glucokinase
name: Q9LPS1
xref: UnificationXref139
feature: FragmentFeature46
cellular location: GO:0005654
comment: Reactome DB_ID: 4183623
display name: GCK

UniProt:F4JMQ0
type: ProteinReference
xref: UnificationXref9309
organism: Arabidopsis thaliana

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q42525
data source: Provenance1
name: glucokinase
name: Q42525
xref: UnificationXref140
feature: FragmentFeature47
cellular location: GO:0005654
comment: Reactome DB_ID: 4183624
display name: GCK

Q9T071
type: Protein
entity reference: Q9T071
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: glucokinase
xref: UnificationXref141
feature: FragmentFeature48
cellular location: GO:0005654
comment: Reactome DB_ID: 4183625
display name: GCK

Q9T071
type: Protein
entity reference: Q9T071
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: HK III
name: HXK3_HUMAN
name: Hexokinase type III
name: hexokinase leukocyte form
name: hexokinase 3
name: hexokinase type 3
xref: UnificationXref130
feature: FragmentFeature42
cellular location: GO:0005829
comment: Reactome DB_ID: 4176909
display name: HK3

Homologues of GCK
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q9FZG4
member physical entity: Q9T071
xref: UnificationXref142
cellular location: GO:0005654
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4183626

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: P93834
data source: Provenance1
name: glucokinase
name: P93834
xref: UnificationXref136
feature: FragmentFeature43
cellular location: GO:0005654
comment: Reactome DB_ID: 4183620
display name: GCK

Q9FZG4
type: Protein
entity reference: Q9FZG4
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: glucokinase
xref: UnificationXref137
feature: FragmentFeature44
cellular location: GO:0005654
comment: Reactome DB_ID: 4183621
display name: GCK

Stoichiometry2040
type: Stoichiometry
physical entity: Homologues of p-S158,S221-ELAVL1(1-326)
stoichiometric coefficient: 1.0

Stoichiometry2041
type: Stoichiometry
physical entity: PhysicalEntity311
stoichiometric coefficient: 1.0

Stoichiometry2042
type: Stoichiometry
physical entity: Homologues of p-S221,S318-ELAVL1(1-326)
stoichiometric coefficient: 1.0

Stoichiometry2043
type: Stoichiometry
physical entity: Homologues of ELAVL1(1-326)
stoichiometric coefficient: 1.0

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q42525
data source: Provenance1
name: HK III
name: HXK3_HUMAN
name: Hexokinase type III
name: Q42525
name: hexokinase leukocyte form
name: hexokinase 3
name: hexokinase type 3
xref: UnificationXref129
feature: FragmentFeature41
cellular location: GO:0005829
comment: Reactome DB_ID: 4176908
display name: HK3

Stoichiometry2044
type: Stoichiometry
physical entity: PhysicalEntity312
stoichiometric coefficient: 1.0

UnificationXref1328
type: UnificationXref
id: REACT_152225
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_152225.1

Stoichiometry2045
type: Stoichiometry
physical entity: PhysicalEntity313
stoichiometric coefficient: 1.0

UnificationXref1327
type: UnificationXref
id: 1629753
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1629753

Stoichiometry2046
type: Stoichiometry
physical entity: PhysicalEntity314
stoichiometric coefficient: 1.0

UniProt:F4JMQ3
type: ProteinReference
xref: UnificationXref13281
organism: Arabidopsis thaliana

Stoichiometry2047
type: Stoichiometry
physical entity: PhysicalEntity315
stoichiometric coefficient: 1.0

UnificationXref1329
type: UnificationXref
id: CHEBI:17268
db: ChEBI

UnificationXref1334
type: UnificationXref
id: 4197574
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197574

UnificationXref1335
type: UnificationXref
id: 4197575
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197575

UnificationXref1336
type: UnificationXref
id: 4197576
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197576

UnificationXref1337
type: UnificationXref
id: 4197577
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197577

UnificationXref1330
type: UnificationXref
id: 426910
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=426910

UnificationXref1331
type: UnificationXref
id: REACT_20018
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_20018.2

UnificationXref1332
type: UnificationXref
id: Q9M8S8
db: UniProt

UnificationXref1333
type: UnificationXref
id: 4197573
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197573

Regulation of DNA replication
type: Pathway
data source: Provenance1
pathway component: REACT 90316.9
pathway component: REACT 77177.9
evidence: Evidence1149
xref: UnificationXref12429
xref: UnificationXref12430
pathway order: PathwayStep1134
pathway order: PathwayStep1133
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LPS1
data source: Provenance1
name: HK III
name: HXK3_HUMAN
name: Q9LPS1
name: Hexokinase type III
name: hexokinase leukocyte form
name: hexokinase 3
name: hexokinase type 3
xref: UnificationXref128
feature: FragmentFeature40
cellular location: GO:0005829
comment: Reactome DB_ID: 4176907
display name: HK3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q56XE8
data source: Provenance1
name: HK III
name: HXK3_HUMAN
name: Hexokinase type III
name: hexokinase leukocyte form
name: hexokinase 3
name: Q56XE8
name: hexokinase type 3
xref: UnificationXref127
feature: FragmentFeature39
cellular location: GO:0005829
comment: Reactome DB_ID: 4176906
display name: HK3

Q9M076
type: Protein
entity reference: Q9M076
data source: Provenance1
name: PFK-B
name: 6-phosphofructokinase, liver type
name: Note: the coordinates are copied over from Homo sapiens.
name: Phosphohexokinase
name: Phosphofructokinase 1
name: Phosphofructo-1-kinase isozyme B
xref: UnificationXref169
feature: FragmentFeature53
cellular location: GO:0005829
comment: Reactome DB_ID: 4176941
display name: PFKL

PFK-B
type: Protein
entity reference: Q94AA4
data source: Provenance1
name: 6-phosphofructokinase, liver type
name: Note: the coordinates are copied over from Homo sapiens.
name: Q94AA4
name: Phosphohexokinase
name: Phosphofructokinase 1
name: Phosphofructo-1-kinase isozyme B
xref: UnificationXref171
feature: FragmentFeature54
cellular location: GO:0005829
comment: Reactome DB_ID: 4176945
display name: PFKL

PFK-B
type: Protein
entity reference: Q8VYN6
data source: Provenance1
name: 6-phosphofructokinase, liver type
name: Note: the coordinates are copied over from Homo sapiens.
name: Phosphohexokinase
name: Phosphofructokinase 1
name: Phosphofructo-1-kinase isozyme B
name: Q8VYN6
xref: UnificationXref165
feature: FragmentFeature51
cellular location: GO:0005829
comment: Reactome DB_ID: 4176933
display name: PFKL

PFK-B
type: Protein
entity reference: Q9C5J7
data source: Provenance1
name: 6-phosphofructokinase, liver type
name: Note: the coordinates are copied over from Homo sapiens.
name: Phosphohexokinase
name: Phosphofructokinase 1
name: Phosphofructo-1-kinase isozyme B
name: Q9C5J7
xref: UnificationXref167
feature: FragmentFeature52
cellular location: GO:0005829
comment: Reactome DB_ID: 4176937
display name: PFKL

Homologues of PFKP
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q9FIK0
member physical entity: Q9M076
xref: UnificationXref185
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4176963

Q9FIK0
type: Protein
entity reference: Q9FIK0
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: PFK-C
name: Phosphohexokinase
name: Phosphofructokinase 1
name: 6-phosphofructokinase, isozyme C
name: Phosphofructo-1-kinase isozyme C
name: 6-phosphofructokinase, type C
name: 6-phosphofructokinase, platelet type
name: K6PP_HUMAN
xref: UnificationXref178
feature: FragmentFeature57
cellular location: GO:0005829
comment: Reactome DB_ID: 4176956
display name: PFKP

Stoichiometry2059
type: Stoichiometry
physical entity: Complex680
stoichiometric coefficient: 1.0

PFK-B
type: Protein
entity reference: Q9M0F9
data source: Provenance1
name: 6-phosphofructokinase, liver type
name: Note: the coordinates are copied over from Homo sapiens.
name: Phosphohexokinase
name: Phosphofructokinase 1
name: Phosphofructo-1-kinase isozyme B
name: Q9M0F9
xref: UnificationXref173
feature: FragmentFeature55
cellular location: GO:0005829
comment: Reactome DB_ID: 4176949
display name: PFKL

PFK-B
type: Protein
entity reference: Q9FKG3
data source: Provenance1
name: 6-phosphofructokinase, liver type
name: Note: the coordinates are copied over from Homo sapiens.
name: Phosphohexokinase
name: Phosphofructokinase 1
name: Phosphofructo-1-kinase isozyme B
name: Q9FKG3
xref: UnificationXref175
feature: FragmentFeature56
cellular location: GO:0005829
comment: Reactome DB_ID: 4176953
display name: PFKL

Stoichiometry2057
type: Stoichiometry
physical entity: PhysicalEntity316
stoichiometric coefficient: 1.0

Stoichiometry2058
type: Stoichiometry
physical entity: Complex752
stoichiometric coefficient: 1.0

Stoichiometry2055
type: Stoichiometry
physical entity: Complex753
stoichiometric coefficient: 1.0

UnificationXref1339
type: UnificationXref
id: 4197579
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197579

Stoichiometry2056
type: Stoichiometry
physical entity: Protein2957
stoichiometric coefficient: 1.0

UnificationXref1338
type: UnificationXref
id: 4197578
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197578

Stoichiometry2053
type: Stoichiometry
physical entity: NCBP 20 kDa subunit
stoichiometric coefficient: 1.0

Homologues of PFKL
type: Protein
data source: Provenance1
member physical entity: PFK-B
member physical entity: Q9M076
member physical entity: Q9FIK0
xref: UnificationXref176
cellular location: GO:0005829
comment: Reactome DB_ID: 4176954
comment: Converted from EntitySet in Reactome

Stoichiometry2054
type: Stoichiometry
physical entity: Note: the coordinates are copied over from Homo sapiens.
stoichiometric coefficient: 1.0

Q9FIK0
type: Protein
entity reference: Q9FIK0
data source: Provenance1
name: PFK-B
name: 6-phosphofructokinase, liver type
name: Note: the coordinates are copied over from Homo sapiens.
name: Phosphohexokinase
name: Phosphofructokinase 1
name: Phosphofructo-1-kinase isozyme B
xref: UnificationXref163
feature: FragmentFeature50
cellular location: GO:0005829
comment: Reactome DB_ID: 4176929
display name: PFKL

Stoichiometry2051
type: Stoichiometry
physical entity: Complex641
stoichiometric coefficient: 1.0

Stoichiometry2052
type: Stoichiometry
physical entity: Protein2936
stoichiometric coefficient: 1.0

Stoichiometry2050
type: Stoichiometry
physical entity: SmallMolecule1014
stoichiometric coefficient: 1.0

UnificationXref1343
type: UnificationXref
id: 870330
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=870330

UnificationXref1344
type: UnificationXref
id: REACT_27390
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_27390.2

UnificationXref1341
type: UnificationXref
id: REACT_157599
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_157599.3

UnificationXref1342
type: UnificationXref
id: CHEBI:18297
db: ChEBI

UnificationXref1347
type: UnificationXref
id: CHEBI:4170
db: ChEBI

UnificationXref1348
type: UnificationXref
id: 1629756
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1629756

http://identifiers.org/pubmed/8723348
type: PublicationXref
id: 8723348
author: Jefferson, AB
author: Pot, DA
author: Deuter-Reinhard, M
author: Masiarz, FR
author: Cousens, LS
author: Williams, LT
author: Chin, SM
author: Norris, FA
author: Kavanaugh, WM
author: Majerus, PW
db: Pubmed
title: Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2
source: Curr Biol 6:438-45
year: 1996

UnificationXref1345
type: UnificationXref
id: 4197581
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197581

UnificationXref1346
type: UnificationXref
id: REACT_155762
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_155762.3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: P34795
data source: Provenance1
name: P34795
name: Phosphoglucose isomerase
name: NLK
name: PGI
name: SA-36
name: Sperm antigen-36
name: Neuroleukin
name: Glucose-6-phosphate isomerase
name: PHI
name: Phosphohexose isomerase
xref: UnificationXref155
feature: FragmentFeature49
cellular location: GO:0005829
comment: Reactome DB_ID: 4176979
display name: GPI

UnificationXref1340
type: UnificationXref
id: 4197770
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197770

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q94AA4
data source: Provenance1
name: PFK-C
name: Q94AA4
name: Phosphohexokinase
name: Phosphofructokinase 1
name: 6-phosphofructokinase, isozyme C
name: Phosphofructo-1-kinase isozyme C
name: 6-phosphofructokinase, type C
name: 6-phosphofructokinase, platelet type
name: K6PP_HUMAN
xref: UnificationXref182
feature: FragmentFeature61
cellular location: GO:0005829
comment: Reactome DB_ID: 4176960
display name: PFKP

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9M0F9
data source: Provenance1
name: PFK-C
name: Phosphohexokinase
name: Phosphofructokinase 1
name: 6-phosphofructokinase, isozyme C
name: Phosphofructo-1-kinase isozyme C
name: Q9M0F9
name: 6-phosphofructokinase, type C
name: 6-phosphofructokinase, platelet type
name: K6PP_HUMAN
xref: UnificationXref183
feature: FragmentFeature62
cellular location: GO:0005829
comment: Reactome DB_ID: 4176961
display name: PFKP

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FKG3
data source: Provenance1
name: PFK-C
name: Phosphohexokinase
name: Phosphofructokinase 1
name: 6-phosphofructokinase, isozyme C
name: Phosphofructo-1-kinase isozyme C
name: Q9FKG3
name: 6-phosphofructokinase, type C
name: 6-phosphofructokinase, platelet type
name: K6PP_HUMAN
xref: UnificationXref184
feature: FragmentFeature63
cellular location: GO:0005829
comment: Reactome DB_ID: 4176962
display name: PFKP

http://identifiers.org/pubmed/1894595
type: PublicationXref
id: 1894595
author: Burbaum, JJ
author: Schimmel, P
db: Pubmed
title: Structural relationships and the classification of aminoacyl-tRNA synthetases
source: J Biol Chem 266:16965-8
year: 1991

Homologues of ALDOB
type: Protein
data source: Provenance1
member physical entity: Q9SJQ9
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref233
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4176809

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: P22197
data source: Provenance1
name: Fructose-bisphosphate aldolase B
name: P22197
name: Liver-type aldolase
xref: UnificationXref214
feature: FragmentFeature64
cellular location: GO:0005829
comment: Reactome DB_ID: 4176782
display name: ALDOB

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8W4G8
data source: Provenance1
name: Q8W4G8
name: Fructose-bisphosphate aldolase B
name: Liver-type aldolase
xref: UnificationXref216
feature: FragmentFeature65
cellular location: GO:0005829
comment: Reactome DB_ID: 4176786
display name: ALDOB

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4KGQ0
data source: Provenance1
name: F4KGQ0
name: Fructose-bisphosphate aldolase B
name: Liver-type aldolase
xref: UnificationXref218
feature: FragmentFeature66
cellular location: GO:0005829
comment: Reactome DB_ID: 4176788
display name: ALDOB

Stoichiometry2066
type: Stoichiometry
physical entity: Complex755
stoichiometric coefficient: 1.0

Stoichiometry2067
type: Stoichiometry
physical entity: Homologues of RNPS1
stoichiometric coefficient: 1.0

UnificationXref1349
type: UnificationXref
id: REACT_152414
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_152414.1

Stoichiometry2068
type: Stoichiometry
physical entity: Homologues of UPF2
stoichiometric coefficient: 1.0

Stoichiometry2069
type: Stoichiometry
physical entity: Complex754
stoichiometric coefficient: 1.0

Stoichiometry2062
type: Stoichiometry
physical entity: Homologues of RBM8A
stoichiometric coefficient: 1.0

Stoichiometry2063
type: Stoichiometry
physical entity: PhysicalEntity318
stoichiometric coefficient: 1.0

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8VYN6
data source: Provenance1
name: PFK-C
name: Phosphohexokinase
name: Phosphofructokinase 1
name: 6-phosphofructokinase, isozyme C
name: Phosphofructo-1-kinase isozyme C
name: 6-phosphofructokinase, type C
name: 6-phosphofructokinase, platelet type
name: Q8VYN6
name: K6PP_HUMAN
xref: UnificationXref179
feature: FragmentFeature58
cellular location: GO:0005829
comment: Reactome DB_ID: 4176957
display name: PFKP

Stoichiometry2064
type: Stoichiometry
physical entity: Complex756
stoichiometric coefficient: 1.0

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9C5J7
data source: Provenance1
name: PFK-C
name: Phosphohexokinase
name: Phosphofructokinase 1
name: 6-phosphofructokinase, isozyme C
name: Phosphofructo-1-kinase isozyme C
name: Q9C5J7
name: 6-phosphofructokinase, type C
name: 6-phosphofructokinase, platelet type
name: K6PP_HUMAN
xref: UnificationXref180
feature: FragmentFeature59
cellular location: GO:0005829
comment: Reactome DB_ID: 4176958
display name: PFKP

Stoichiometry2065
type: Stoichiometry
physical entity: PhysicalEntity319
stoichiometric coefficient: 1.0

Q9M076
type: Protein
entity reference: Q9M076
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: PFK-C
name: Phosphohexokinase
name: Phosphofructokinase 1
name: 6-phosphofructokinase, isozyme C
name: Phosphofructo-1-kinase isozyme C
name: 6-phosphofructokinase, type C
name: 6-phosphofructokinase, platelet type
name: K6PP_HUMAN
xref: UnificationXref181
feature: FragmentFeature60
cellular location: GO:0005829
comment: Reactome DB_ID: 4176959
display name: PFKP

UnificationXref1352
type: UnificationXref
id: REACT_150575
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_150575.1

UnificationXref1353
type: UnificationXref
id: Q9LX12
db: UniProt

Stoichiometry2061
type: Stoichiometry
physical entity: Protein3716
stoichiometric coefficient: 1.0

UnificationXref1354
type: UnificationXref
id: 4197723
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197723

Stoichiometry2060
type: Stoichiometry
physical entity: PhysicalEntity317
stoichiometric coefficient: 1.0

UnificationXref1355
type: UnificationXref
id: Q38862
db: UniProt

UnificationXref1356
type: UnificationXref
id: 4197727
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197727

UnificationXref1357
type: UnificationXref
id: P42801
db: UniProt

UnificationXref1358
type: UnificationXref
id: 4197731
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197731

UnificationXref1359
type: UnificationXref
id: 4197732
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197732

UnificationXref1350
type: UnificationXref
id: CHEBI:18169
db: ChEBI

UnificationXref1351
type: UnificationXref
id: 1629731
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1629731

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LZR9
data source: Provenance1
name: Q9LZR9
name: Fructose-bisphosphate aldolase B
name: Liver-type aldolase
xref: UnificationXref226
feature: FragmentFeature70
cellular location: GO:0005829
comment: Reactome DB_ID: 4176802
display name: ALDOB

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: B3H6D7
data source: Provenance1
name: B3H6D7
name: Fructose-bisphosphate aldolase B
name: Liver-type aldolase
xref: UnificationXref224
feature: FragmentFeature69
cellular location: GO:0005829
comment: Reactome DB_ID: 4176800
display name: ALDOB

UniProt:F4JMT8
type: ProteinReference
xref: UnificationXref15444
organism: Arabidopsis thaliana

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LF98
data source: Provenance1
name: Fructose-bisphosphate aldolase B
name: Q9LF98
name: Liver-type aldolase
xref: UnificationXref222
feature: FragmentFeature68
cellular location: GO:0005829
comment: Reactome DB_ID: 4176796
display name: ALDOB

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65581
data source: Provenance1
name: O65581
name: Fructose-bisphosphate aldolase B
name: Liver-type aldolase
xref: UnificationXref220
feature: FragmentFeature67
cellular location: GO:0005829
comment: Reactome DB_ID: 4176792
display name: ALDOB

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SKP6
data source: Provenance1
name: triosephosphate isomerase monomer
name: TPI1
name: Q9SKP6
name: TPIS_HUMAN
name: Triosephosphate isomerase
xref: UnificationXref240
feature: FragmentFeature75
cellular location: GO:0005829
comment: Reactome DB_ID: 4176921
display name: TIM

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: P48491
data source: Provenance1
name: triosephosphate isomerase monomer
name: TPI1
name: TPIS_HUMAN
name: P48491
name: Triosephosphate isomerase
xref: UnificationXref238
feature: FragmentFeature74
cellular location: GO:0005829
comment: Reactome DB_ID: 4176917
display name: TIM

Homologues of TPI1
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref241
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4176922

Q9SJQ9
type: Protein
entity reference: Q9SJQ9
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Fructose-bisphosphate aldolase B
name: Liver-type aldolase
xref: UnificationXref232
feature: FragmentFeature73
cellular location: GO:0005829
comment: Reactome DB_ID: 4176808
display name: ALDOB

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LET3
data source: Provenance1
name: Fructose-bisphosphate aldolase B
name: Q8LET3
name: Liver-type aldolase
xref: UnificationXref230
feature: FragmentFeature72
cellular location: GO:0005829
comment: Reactome DB_ID: 4176806
display name: ALDOB

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q56Z19
data source: Provenance1
name: Q56Z19
name: Fructose-bisphosphate aldolase B
name: Liver-type aldolase
xref: UnificationXref228
feature: FragmentFeature71
cellular location: GO:0005829
comment: Reactome DB_ID: 4176804
display name: ALDOB

UnificationXref1362
type: UnificationXref
id: REACT_156517
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_156517.3

UnificationXref1361
type: UnificationXref
id: 4197735
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197735

UnificationXref1360
type: UnificationXref
id: 4197733
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197733

UnificationXref1369
type: UnificationXref
id: CHEBI:16113
db: ChEBI

UnificationXref1368
type: UnificationXref
id: REACT_159420
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_159420.3

UnificationXref1367
type: UnificationXref
id: 4199994
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199994

UnificationXref1366
type: UnificationXref
id: REACT_156764
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_156764.3

UnificationXref1365
type: UnificationXref
id: 4199993
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199993

UnificationXref1364
type: UnificationXref
id: REACT_155586
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_155586.3

UnificationXref1363
type: UnificationXref
id: 4197768
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197768

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LDF6
data source: Provenance1
name: Mitochondrial dicarboxylate carrier protein
name: SLC25A10
xref: UnificationXref288
feature: FragmentFeature77
cellular location: GO:0005743
comment: Reactome DB_ID: 4188316
display name: Q8LDF6

Homologues of SLC25A10
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref299
cellular location: GO:0005743
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4188331

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SB52
data source: Provenance1
name: Mitochondrial dicarboxylate carrier protein
name: SLC25A10
xref: UnificationXref292
feature: FragmentFeature79
cellular location: GO:0005743
comment: Reactome DB_ID: 4188322
display name: Q9SB52

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SJY5
data source: Provenance1
name: Mitochondrial dicarboxylate carrier protein
name: SLC25A10
xref: UnificationXref290
feature: FragmentFeature78
cellular location: GO:0005743
comment: Reactome DB_ID: 4188318
display name: Q9SJY5

Stoichiometry2001
type: Stoichiometry
physical entity: Note: the coordinates are copied over from Homo sapiens.
stoichiometric coefficient: 1.0

Stoichiometry2000
type: Stoichiometry
physical entity: Complex728
stoichiometric coefficient: 1.0

Stoichiometry2003
type: Stoichiometry
physical entity: Homologues of EXOSC7
stoichiometric coefficient: 1.0

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04983
data source: Provenance1
name: Pyruvic carboxylase
name: Pyruvate carboxylase, mitochondrial precursor
name: O04983
name: pyruvate carboxylase
xref: UnificationXref265
feature: FragmentFeature76
cellular location: GO:0005759
comment: Reactome DB_ID: 4176999
display name: PC

http://identifiers.org/pubmed/8167409
type: PublicationXref
id: 8167409
author: McMahon, Jill A
author: Smolich, Beverly D
author: McMahon, Andrew P
author: Papkoff, Jackie
db: Pubmed
title: Wnt family proteins are secreted and associated with the cell surface
source: Mol. Biol. Cell 4:1267-75
year: 1993

Stoichiometry2002
type: Stoichiometry
physical entity: PhysicalEntity303
stoichiometric coefficient: 1.0

Stoichiometry2005
type: Stoichiometry
physical entity: Homologues of EXOSC6
stoichiometric coefficient: 1.0

Stoichiometry2004
type: Stoichiometry
physical entity: Q9LX74
stoichiometric coefficient: 1.0

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: P93819
data source: Provenance1
name: P93819
name: malate dehydrogenase 1
xref: UnificationXref314
feature: FragmentFeature83
cellular location: GO:0005829
comment: Reactome DB_ID: 4185516
display name: MDH1

Stoichiometry2007
type: Stoichiometry
physical entity: Complex731
stoichiometric coefficient: 1.0

Stoichiometry2006
type: Stoichiometry
physical entity: Homologues of EXOSC9
stoichiometric coefficient: 1.0

Stoichiometry2009
type: Stoichiometry
physical entity: Note: the coordinates are copied over from Homo sapiens.
stoichiometric coefficient: 1.0

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q94K32
data source: Provenance1
name: Mitochondrial dicarboxylate carrier protein
name: SLC25A10
xref: UnificationXref296
feature: FragmentFeature81
cellular location: GO:0005743
comment: Reactome DB_ID: 4188326
display name: Q94K32

Stoichiometry2008
type: Stoichiometry
physical entity: Homologues of EXOSC1
stoichiometric coefficient: 1.0

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WL82
data source: Provenance1
name: Mitochondrial dicarboxylate carrier protein
name: SLC25A10
xref: UnificationXref294
feature: FragmentFeature80
cellular location: GO:0005743
comment: Reactome DB_ID: 4188324
display name: Q0WL82

Homologues of MDH1
type: Protein
data source: Provenance1
member physical entity: Protein101
member physical entity: Protein100
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref319
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4185525

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FY68
data source: Provenance1
name: Mitochondrial dicarboxylate carrier protein
name: SLC25A10
xref: UnificationXref298
feature: FragmentFeature82
cellular location: GO:0005743
comment: Reactome DB_ID: 4188330
display name: Q9FY68

UnificationXref1371
type: UnificationXref
id: REACT_7360
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_7360.2

UnificationXref1370
type: UnificationXref
id: 171149
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=171149

UnificationXref1373
type: UnificationXref
id: REACT_7756
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_7756.3

UnificationXref1372
type: UnificationXref
id: 176478
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=176478

UnificationXref1379
type: UnificationXref
id: 4187998
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187998

UnificationXref1378
type: UnificationXref
id: F4I9G5
db: UniProt

UnificationXref1375
type: UnificationXref
id: 4187992
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187992

UnificationXref1374
type: UnificationXref
id: F4JTN1
db: UniProt

UnificationXref1377
type: UnificationXref
id: 4187994
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187994

UnificationXref1376
type: UnificationXref
id: F4JTN0
db: UniProt

Stoichiometry2014
type: Stoichiometry
physical entity: Homologues of LSM6
stoichiometric coefficient: 1.0

Stoichiometry2013
type: Stoichiometry
physical entity: PhysicalEntity304
stoichiometric coefficient: 1.0

Stoichiometry2012
type: Stoichiometry
physical entity: Note: the coordinates are copied over from Homo sapiens.
stoichiometric coefficient: 1.0

Stoichiometry2011
type: Stoichiometry
physical entity: Homologues of DIS3
stoichiometric coefficient: 1.0

Stoichiometry2010
type: Stoichiometry
physical entity: Homologues of EXOSC3
stoichiometric coefficient: 1.0

Stoichiometry2019
type: Stoichiometry
physical entity: Homologues of LSM4
stoichiometric coefficient: 1.0

UniProt:F4JMR0
type: ProteinReference
xref: UnificationXref775
organism: Arabidopsis thaliana

Stoichiometry2018
type: Stoichiometry
physical entity: Homologues of LSM1
stoichiometric coefficient: 1.0

Stoichiometry2017
type: Stoichiometry
physical entity: Homologues of LSM3(2-102)
stoichiometric coefficient: 1.0

Stoichiometry2016
type: Stoichiometry
physical entity: Homologues of LSM5(2-91)
stoichiometric coefficient: 1.0

Stoichiometry2015
type: Stoichiometry
physical entity: Homologues of LSM2
stoichiometric coefficient: 1.0

UnificationXref1380
type: UnificationXref
id: 4187999
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187999

UnificationXref1384
type: UnificationXref
id: 265546
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=265546

UnificationXref1383
type: UnificationXref
id: CHEBI:26125
db: ChEBI

UnificationXref1382
type: UnificationXref
id: REACT_111952
db: Reactome
id version: 8
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_111952.8

UnificationXref1381
type: UnificationXref
id: 4188001
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188001

UnificationXref1388
type: UnificationXref
id: 4188004
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188004

UnificationXref1387
type: UnificationXref
id: REACT_13916
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_13916.1

UnificationXref1386
type: UnificationXref
id: 265525
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=265525

UnificationXref1385
type: UnificationXref
id: REACT_13826
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_13826.1

UnificationXref1389
type: UnificationXref
id: REACT_114138
db: Reactome
id version: 8
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_114138.8

Stoichiometry2023
type: Stoichiometry
physical entity: Homologues of p-S83,S87-HNRNPD-3
stoichiometric coefficient: 2.0

Stoichiometry2022
type: Stoichiometry
physical entity: Homologues of HNRNPD-4
stoichiometric coefficient: 2.0

Stoichiometry2025
type: Stoichiometry
physical entity: Homologues of HNRNPD-4
stoichiometric coefficient: 4.0

Stoichiometry2024
type: Stoichiometry
physical entity: Complex734
stoichiometric coefficient: 2.0

Stoichiometry2021
type: Stoichiometry
physical entity: PhysicalEntity301
stoichiometric coefficient: 1.0

Stoichiometry2020
type: Stoichiometry
physical entity: Complex732
stoichiometric coefficient: 1.0

Stoichiometry2027
type: Stoichiometry
physical entity: Complex738
stoichiometric coefficient: 1.0

Stoichiometry2026
type: Stoichiometry
physical entity: Homologues of p-S83,S87-HNRNPD-3
stoichiometric coefficient: 4.0

Stoichiometry2029
type: Stoichiometry
physical entity: PhysicalEntity305
stoichiometric coefficient: 1.0

Stoichiometry2028
type: Stoichiometry
physical entity: PhysicalEntity305
stoichiometric coefficient: 1.0

UnificationXref1391
type: UnificationXref
id: 265479
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=265479

UnificationXref1390
type: UnificationXref
id: CHEBI:49040
db: ChEBI

UnificationXref1393
type: UnificationXref
id: 265495
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=265495

UnificationXref1392
type: UnificationXref
id: REACT_13936
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_13936.2

UnificationXref1395
type: UnificationXref
id: 4188002
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188002

UnificationXref1394
type: UnificationXref
id: REACT_13861
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_13861.2

UnificationXref1397
type: UnificationXref
id: REACT_112899
db: Reactome
id version: 8
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_112899.8

UnificationXref1396
type: UnificationXref
id: 4188003
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188003

UnificationXref1399
type: UnificationXref
id: REACT_96633
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_96633.9

UnificationXref1398
type: UnificationXref
id: 4199765
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199765

5-PP-InsP5
type: SmallMoleculeReference
name: 5-PP-InsP5 [ChEBI:2119]
name: 5-Diphosphoinositol pentakisphosphate
xref: UnificationXref1158

Rheumatoid synovial collagenase
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Fibroblast collagenase
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: Q9ZUJ5
name: Matrix metalloproteinase-1
name: MMP1(100-469)
xref: UnificationXref15497
feature: FragmentFeature4669
cellular location: GO:0005576
comment: Reactome DB_ID: 4196001
display name: MMP1

Homologues of MMP1(100-469)
type: Protein
data source: Provenance1
member physical entity: Rheumatoid synovial collagenase
xref: UnificationXref15507
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196011

Fibroblast collagenase
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1 fragment 54-83
name: Matrix metalloproteinase-1
name: MMP1(54-83)
xref: UnificationXref15493
feature: FragmentFeature4668
cellular location: GO:0005576
comment: Reactome DB_ID: 4196284
display name: Q8GWW6

Rheumatoid synovial collagenase
type: Protein
entity reference: O04529
data source: Provenance1
name: Fibroblast collagenase
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: Matrix metalloproteinase-1
name: MMP1(100-469)
name: O04529
xref: UnificationXref15504
feature: FragmentFeature4676
cellular location: GO:0005576
comment: Reactome DB_ID: 4196008
display name: MMP1

Rheumatoid synovial collagenase
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Fibroblast collagenase
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: Q0WVU1
name: Matrix metalloproteinase-1
name: MMP1(100-469)
xref: UnificationXref15503
feature: FragmentFeature4675
cellular location: GO:0005576
comment: Reactome DB_ID: 4196007
display name: MMP1

Rheumatoid synovial collagenase
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Fibroblast collagenase
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: Matrix metalloproteinase-1
name: MMP1(100-469)
name: Q84W77
xref: UnificationXref15502
feature: FragmentFeature4674
cellular location: GO:0005576
comment: Reactome DB_ID: 4196006
display name: MMP1

Rheumatoid synovial collagenase
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Fibroblast collagenase
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: Matrix metalloproteinase-1
name: MMP1(100-469)
name: Q5XF51
xref: UnificationXref15501
feature: FragmentFeature4673
cellular location: GO:0005576
comment: Reactome DB_ID: 4196005
display name: MMP1

Rheumatoid synovial collagenase
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Fibroblast collagenase
name: Q8LET7
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: Matrix metalloproteinase-1
name: MMP1(100-469)
xref: UnificationXref15500
feature: FragmentFeature4672
cellular location: GO:0005576
comment: Reactome DB_ID: 4196004
display name: MMP1

Rheumatoid synovial collagenase
type: Protein
entity reference: O65340
data source: Provenance1
name: Fibroblast collagenase
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: Matrix metalloproteinase-1
name: MMP1(100-469)
name: O65340
xref: UnificationXref15499
feature: FragmentFeature4671
cellular location: GO:0005576
comment: Reactome DB_ID: 4196003
display name: MMP1

Rheumatoid synovial collagenase
type: Protein
entity reference: O23507
data source: Provenance1
name: Fibroblast collagenase
name: O23507
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: Matrix metalloproteinase-1
name: MMP1(100-469)
xref: UnificationXref15498
feature: FragmentFeature4670
cellular location: GO:0005576
comment: Reactome DB_ID: 4196002
display name: MMP1

Rheumatoid synovial collagenase
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Fibroblast collagenase
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: Q8GWW6
name: Matrix metalloproteinase-1
name: MMP1(100-469)
xref: UnificationXref15506
feature: FragmentFeature4678
cellular location: GO:0005576
comment: Reactome DB_ID: 4196010
display name: MMP1

Rheumatoid synovial collagenase
type: Protein
entity reference: O48680
data source: Provenance1
name: Fibroblast collagenase
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: Matrix metalloproteinase-1
name: MMP1(100-469)
name: O48680
xref: UnificationXref15505
feature: FragmentFeature4677
cellular location: GO:0005576
comment: Reactome DB_ID: 4196009
display name: MMP1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Q9ZUJ5
name: MMP2(110-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: 70 kDa gelatinase
xref: UnificationXref15508
feature: FragmentFeature4679
cellular location: GO:0005576
comment: Reactome DB_ID: 4195966
display name: MMP2

Homologues of MMP2(110-660)
type: Protein
data source: Provenance1
member physical entity: O23507
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q8LET7
xref: UnificationXref15518
cellular location: GO:0005576
comment: Reactome DB_ID: 4195976
comment: Converted from EntitySet in Reactome

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Q0WVU1
name: MMP2(110-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: 70 kDa gelatinase
xref: UnificationXref15514
feature: FragmentFeature4685
cellular location: GO:0005576
comment: Reactome DB_ID: 4195972
display name: MMP2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Q84W77
name: MMP2(110-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: 70 kDa gelatinase
xref: UnificationXref15513
feature: FragmentFeature4684
cellular location: GO:0005576
comment: Reactome DB_ID: 4195971
display name: MMP2

http://identifiers.org/pubmed/12655297
type: PublicationXref
id: 12655297
author: Janicke, RU
author: Schulze-Osthoff, K
author: Fischer, U
db: Pubmed
title: Many cuts to ruin: a comprehensive update of caspase substrates
source: Cell Death Differ 10:76-100
year: 2003

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: O65340
name: MMP2(110-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: 70 kDa gelatinase
xref: UnificationXref15510
feature: FragmentFeature4681
cellular location: GO:0005576
comment: Reactome DB_ID: 4195968
display name: MMP2

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP2(110-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: 70 kDa gelatinase
xref: UnificationXref15509
feature: FragmentFeature4680
cellular location: GO:0005576
comment: Reactome DB_ID: 4195967
display name: MMP2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Q5XF51
name: MMP2(110-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: 70 kDa gelatinase
xref: UnificationXref15512
feature: FragmentFeature4683
cellular location: GO:0005576
comment: Reactome DB_ID: 4195970
display name: MMP2

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP2(110-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: 70 kDa gelatinase
xref: UnificationXref15511
feature: FragmentFeature4682
cellular location: GO:0005576
comment: Reactome DB_ID: 4195969
display name: MMP2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: O04529
name: MMP2(110-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: 70 kDa gelatinase
xref: UnificationXref15515
feature: FragmentFeature4686
cellular location: GO:0005576
comment: Reactome DB_ID: 4195973
display name: MMP2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Q9ZUJ5
name: Stromelysin-1
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15519
feature: FragmentFeature4689
cellular location: GO:0005576
comment: Reactome DB_ID: 4196012
display name: MMP3

Homologues of MMP3
type: Protein
data source: Provenance1
member physical entity: Q8LET7
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: O23507
xref: UnificationXref15529
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196022

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Q8GWW6
name: MMP2(110-660)
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: 70 kDa gelatinase
xref: UnificationXref15517
feature: FragmentFeature4688
cellular location: GO:0005576
comment: Reactome DB_ID: 4195975
display name: MMP2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP2(110-660)
name: O48680
name: MMP2_HUMAN
name: Matrix metalloproteinase-2
name: 70 kDa gelatinase
xref: UnificationXref15516
feature: FragmentFeature4687
cellular location: GO:0005576
comment: Reactome DB_ID: 4195974
display name: MMP2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Stromelysin-1
name: Q5XF51
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15523
feature: FragmentFeature4693
cellular location: GO:0005576
comment: Reactome DB_ID: 4196016
display name: MMP3

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Stromelysin-1
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15522
feature: FragmentFeature4692
cellular location: GO:0005576
comment: Reactome DB_ID: 4196015
display name: MMP3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: Stromelysin-1
name: O65340
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15521
feature: FragmentFeature4691
cellular location: GO:0005576
comment: Reactome DB_ID: 4196014
display name: MMP3

http://identifiers.org/pubmed/18240029
type: PublicationXref
id: 18240029
author: Luttrell, LM
db: Pubmed
title: Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors
source: Mol Biotechnol 39:239-64
year: 2008

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Stromelysin-1
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15520
feature: FragmentFeature4690
cellular location: GO:0005576
comment: Reactome DB_ID: 4196013
display name: MMP3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Stromelysin-1
name: Q84W77
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15524
feature: FragmentFeature4694
cellular location: GO:0005576
comment: Reactome DB_ID: 4196017
display name: MMP3

http://identifiers.org/pubmed/16321791
type: PublicationXref
id: 16321791
author: Joseph, JW
author: MacDonald, PE
author: Rorsman, P
db: Pubmed
title: Glucose-sensing mechanisms in pancreatic beta-cells
source: Philos Trans R Soc Lond B Biol Sci 360:2211-25
year: 2005

SequenceSite2697
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2696
type: SequenceSite
position status: EQUAL
sequence position: 325

SequenceSite2699
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2698
type: SequenceSite
position status: EQUAL
sequence position: 311

SequenceSite2690
type: SequenceSite
position status: EQUAL
sequence position: 325

SequenceSite2691
type: SequenceSite
position status: EQUAL
sequence position: 22

SequenceSite2692
type: SequenceSite
position status: EQUAL
sequence position: 325

SequenceSite2693
type: SequenceSite
position status: EQUAL
sequence position: 22

SequenceSite2694
type: SequenceSite
position status: EQUAL
sequence position: 325

SequenceSite2695
type: SequenceSite
position status: EQUAL
sequence position: 22

Developmental Biology
type: Pathway
data source: Provenance1
pathway component: REACT 157746.3
pathway component: REACT 114665.8
pathway component: REACT 89352.9
evidence: Evidence1765
xref: UnificationXref18995
xref: UnificationXref18996
pathway order: PathwayStep1731
pathway order: PathwayStep1727
pathway order: PathwayStep1733
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/17560368
type: PublicationXref
id: 17560368
author: Peters, L
author: Meister, G
db: Pubmed
title: Argonaute proteins: mediators of RNA silencing
source: Mol Cell 26:611-23
year: 2007

UnificationXref17360
type: UnificationXref
id: 4188921
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188921

UnificationXref17361
type: UnificationXref
id: 4188922
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188922

SequenceSite2640
type: SequenceSite
position status: EQUAL
sequence position: 134

UnificationXref17367
type: UnificationXref
id: 4188908
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188908

SequenceSite2646
type: SequenceSite
position status: EQUAL
sequence position: 243

UnificationXref17366
type: UnificationXref
id: Q9FG37
db: UniProt

SequenceSite2645
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17369
type: UnificationXref
id: 4188899
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188899

SequenceSite2648
type: SequenceSite
position status: EQUAL
sequence position: 243

UnificationXref17368
type: UnificationXref
id: Q9LF43
db: UniProt

SequenceSite2647
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17363
type: UnificationXref
id: 4188916
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188916

SequenceSite2642
type: SequenceSite
position status: EQUAL
sequence position: 243

UnificationXref17362
type: UnificationXref
id: 4188923
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188923

SequenceSite2641
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17365
type: UnificationXref
id: 4188862
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188862

SequenceSite2644
type: SequenceSite
position status: EQUAL
sequence position: 243

UnificationXref17364
type: UnificationXref
id: Q9M350
db: UniProt

SequenceSite2643
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2649
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/6311078
type: PublicationXref
id: 6311078
author: Hammarström, Sven
db: Pubmed
title: Leukotrienes
source: Annu Rev Biochem 52:355-77
year: 1983

CREB phosphorylation through the activation of CaMKK
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction1112
evidence: Evidence1798
xref: UnificationXref19202
xref: UnificationXref19203
pathway order: PathwayStep1762
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Role of LAT2/NTAL/LAB on calcium mobilization
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction596
pathway component: REACT 91146.9
evidence: Evidence908
xref: UnificationXref10693
xref: UnificationXref10694
pathway order: PathwayStep838
pathway order: PathwayStep849
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

UnificationXref17350
type: UnificationXref
id: REACT_126608
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_126608.5

UnificationXref17358
type: UnificationXref
id: 4188920
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188920

SequenceSite2637
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17357
type: UnificationXref
id: F4I9A1
db: UniProt

SequenceSite2636
type: SequenceSite
position status: EQUAL
sequence position: 134

UnificationXref17356
type: UnificationXref
id: 4188919
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188919

SequenceSite2635
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17355
type: UnificationXref
id: F4I9A2
db: UniProt

SequenceSite2634
type: SequenceSite
position status: EQUAL
sequence position: 134

UnificationXref17354
type: UnificationXref
id: 4188918
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188918

SequenceSite2633
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17353
type: UnificationXref
id: Q9FYL7
db: UniProt

SequenceSite2632
type: SequenceSite
position status: EQUAL
sequence position: 134

UnificationXref17352
type: UnificationXref
id: REACT_128219
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_128219.5

SequenceSite2631
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17351
type: UnificationXref
id: 4199631
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199631

SequenceSite2630
type: SequenceSite
position status: EQUAL
sequence position: 134

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: B3H5N7
data source: Provenance1
name: B3H5N7
name: hUpf3B
name: UPf3B
xref: UnificationXref15359
feature: FragmentFeature4611
cellular location: GO:0005829
comment: Reactome DB_ID: 4193865
display name: UPF3B

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FX10
data source: Provenance1
name: Q9FX10
name: hUpf3B
name: UPf3B
xref: UnificationXref15358
feature: FragmentFeature4610
cellular location: GO:0005829
comment: Reactome DB_ID: 4193864
display name: UPF3B

Homologues of UPF3B
type: Protein
data source: Provenance1
member physical entity: Q9FVW4
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15361
cellular location: GO:0005829
comment: Reactome DB_ID: 4193867
comment: Converted from EntitySet in Reactome

Q9FVW4
type: Protein
entity reference: Q9FVW4
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Regulator of nonsense transcripts 3A
name: REN3A_HUMAN
xref: UnificationXref15356
feature: FragmentFeature4609
cellular location: GO:0005829
comment: Reactome DB_ID: 4193862
display name: UPF3A

SequenceSite2639
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17359
type: UnificationXref
id: Q8GXQ6
db: UniProt

SequenceSite2638
type: SequenceSite
position status: EQUAL
sequence position: 134

Q9FVW4
type: Protein
entity reference: Q9FVW4
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: hUpf3B
name: UPf3B
xref: UnificationXref15360
feature: FragmentFeature4612
cellular location: GO:0005829
comment: Reactome DB_ID: 4193866
display name: UPF3B

Homologues of RBM8A
type: Protein
data source: Provenance1
member physical entity: Q9C8K3
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15366
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4193844

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LG23
data source: Provenance1
name: RBM8A/Y14
name: Q8LG23
xref: UnificationXref15363
feature: FragmentFeature4613
cellular location: GO:0005829
comment: Reactome DB_ID: 4193841
display name: RBM8A

Q9C8K3
type: Protein
entity reference: Q9C8K3
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: RBM8A/Y14
xref: UnificationXref15364
feature: FragmentFeature4614
cellular location: GO:0005829
comment: Reactome DB_ID: 4193842
display name: RBM8A

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4I9J7
data source: Provenance1
name: RBM8A/Y14
name: F4I9J7
xref: UnificationXref15365
feature: FragmentFeature4615
cellular location: GO:0005829
comment: Reactome DB_ID: 4193843
display name: RBM8A

Homologues of RNPS1
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15375
cellular location: GO:0005829
comment: Reactome DB_ID: 4193859
comment: Converted from EntitySet in Reactome

UnificationXref17380
type: UnificationXref
id: 4188909
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188909

UnificationXref17381
type: UnificationXref
id: Q0WPZ0
db: UniProt

UnificationXref17382
type: UnificationXref
id: 4188866
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188866

UnificationXref17383
type: UnificationXref
id: F4HUK8
db: UniProt

UnificationXref17385
type: UnificationXref
id: Q9LM94
db: UniProt

SequenceSite2620
type: SequenceSite
position status: EQUAL
sequence position: 650

UnificationXref17384
type: UnificationXref
id: 4188870
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188870

UnificationXref17387
type: UnificationXref
id: 4188873
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188873

SequenceSite2622
type: SequenceSite
position status: EQUAL
sequence position: 650

3beta-Hydroxyandrost-5-en-17-one
type: SmallMoleculeReference
name: Dehydroepiandrosterone [ChEBI:28689]
name: DHEA
name: Dehydroisoandrosterone
name: Dehydroepiandrosterone
name: DHA
xref: UnificationXref7096

UnificationXref17386
type: UnificationXref
id: 4188872
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188872

SequenceSite2621
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17389
type: UnificationXref
id: 4188877
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188877

SequenceSite2624
type: SequenceSite
position status: EQUAL
sequence position: 650

UnificationXref17388
type: UnificationXref
id: F4IZ65
db: UniProt

SequenceSite2623
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2626
type: SequenceSite
position status: EQUAL
sequence position: 650

UniProt:F4JNC9
type: ProteinReference
xref: UnificationXref9523
organism: Arabidopsis thaliana

SequenceSite2625
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2628
type: SequenceSite
position status: EQUAL
sequence position: 650

SequenceSite2627
type: SequenceSite
position status: EQUAL
sequence position: 1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q94AS1
data source: Provenance1
name: Q94AS1
xref: UnificationXref15371
feature: FragmentFeature4616
cellular location: GO:0005829
comment: Reactome DB_ID: 4193855
display name: RNPS1

SequenceSite2629
type: SequenceSite
position status: EQUAL
sequence position: 2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q5E925
data source: Provenance1
name: Q5E925
xref: UnificationXref15373
feature: FragmentFeature4618
cellular location: GO:0005829
comment: Reactome DB_ID: 4193857
display name: RNPS1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SEE9
data source: Provenance1
name: Q9SEE9
xref: UnificationXref15372
feature: FragmentFeature4617
cellular location: GO:0005829
comment: Reactome DB_ID: 4193856
display name: RNPS1

Homologues of UPF2
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15380
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4193854

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4I4H8
data source: Provenance1
name: F4I4H8
xref: UnificationXref15374
feature: FragmentFeature4619
cellular location: GO:0005829
comment: Reactome DB_ID: 4193858
display name: RNPS1

phospho-p-3S1089,S1107-UPF1
type: Protein
entity reference: Q9FJR0
data source: Provenance1
xref: UnificationXref15384
feature: ModificationFeature479
feature: ModificationFeature480
feature: FragmentFeature4622
cellular location: GO:0005829
comment: Reactome DB_ID: 4193822

Homologues of SMG7
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15396
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4193828

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O80955
data source: Provenance1
name: O80955
name: Regulator of nonsense transcripts 2
name: RENT2_HUMAN
xref: UnificationXref15377
feature: FragmentFeature4620
cellular location: GO:0005829
comment: Reactome DB_ID: 4193851
display name: UPF2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4IUX6
data source: Provenance1
name: Regulator of nonsense transcripts 2
name: RENT2_HUMAN
name: F4IUX6
xref: UnificationXref15379
feature: FragmentFeature4621
cellular location: GO:0005829
comment: Reactome DB_ID: 4193853
display name: UPF2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84WB4
data source: Provenance1
name: SMG7_HUMAN
name: Protein SMG7
name: Q84WB4
xref: UnificationXref15389
feature: FragmentFeature4623
cellular location: GO:0005829
comment: Reactome DB_ID: 4193824
display name: SMG7

UnificationXref17371
type: UnificationXref
id: 4188901
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188901

UnificationXref17372
type: UnificationXref
id: F4KGZ8
db: UniProt

UnificationXref17370
type: UnificationXref
id: Q9C5H9
db: UniProt

UnificationXref17376
type: UnificationXref
id: 4188890
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188890

SequenceSite2611
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17375
type: UnificationXref
id: P38558
db: UniProt

SequenceSite2610
type: SequenceSite
position status: EQUAL
sequence position: 650

UnificationXref17374
type: UnificationXref
id: 4188904
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188904

UnificationXref17373
type: UnificationXref
id: 4188903
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188903

SequenceSite2615
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17379
type: UnificationXref
id: 4188895
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188895

SequenceSite2614
type: SequenceSite
position status: EQUAL
sequence position: 650

UnificationXref17378
type: UnificationXref
id: 4188894
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188894

SequenceSite2613
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17377
type: UnificationXref
id: P38557
db: UniProt

SequenceSite2612
type: SequenceSite
position status: EQUAL
sequence position: 650

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FZ99
data source: Provenance1
name: Q9FZ99
name: SMG7_HUMAN
name: Protein SMG7
xref: UnificationXref15393
feature: FragmentFeature4625
cellular location: GO:0005829
comment: Reactome DB_ID: 4193826
display name: SMG7

SequenceSite2619
type: SequenceSite
position status: EQUAL
sequence position: 1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WM39
data source: Provenance1
name: SMG7_HUMAN
name: Q0WM39
name: Protein SMG7
xref: UnificationXref15391
feature: FragmentFeature4624
cellular location: GO:0005829
comment: Reactome DB_ID: 4193825
display name: SMG7

SequenceSite2618
type: SequenceSite
position status: EQUAL
sequence position: 650

SequenceSite2617
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2616
type: SequenceSite
position status: EQUAL
sequence position: 650

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WM39
data source: Provenance1
name: Q0WM39
name: Telomerase-binding protein EST1A
name: EST1A_HUMAN
xref: UnificationXref15399
feature: FragmentFeature4628
cellular location: GO:0005829
comment: Reactome DB_ID: 4193812
display name: SMG6

http://identifiers.org/pubmed/20110263
type: PublicationXref
id: 20110263
author: Kersten, S
author: de Groot, PJ
author: de Vries, SC
author: Muller, M
author: Degenhardt, T
author: Carlberg, C
author: Vaisanen, S
author: Heinaniemi, M
author: van der Meer, DL
db: Pubmed
title: Profiling of promoter occupancy by PPAR{alpha} in human hepatoma cells via ChIP-chip analysis
source: Nucleic Acids Res
year: 2010

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84WB4
data source: Provenance1
name: Telomerase-binding protein EST1A
name: Q84WB4
name: EST1A_HUMAN
xref: UnificationXref15398
feature: FragmentFeature4627
cellular location: GO:0005829
comment: Reactome DB_ID: 4193810
display name: SMG6

Homologues of SMG6
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15402
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4193819

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: A9QM73
data source: Provenance1
name: A9QM73
name: SMG7_HUMAN
name: Protein SMG7
xref: UnificationXref15395
feature: FragmentFeature4626
cellular location: GO:0005829
comment: Reactome DB_ID: 4193827
display name: SMG7

SequenceSite2682
type: SequenceSite
position status: EQUAL
sequence position: 925

SequenceSite2681
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2684
type: SequenceSite
position status: EQUAL
sequence position: 925

SequenceSite2683
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2680
type: SequenceSite
position status: EQUAL
sequence position: 925

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: A9QM73
data source: Provenance1
name: A9QM73
name: Telomerase-binding protein EST1A
name: EST1A_HUMAN
xref: UnificationXref15401
feature: FragmentFeature4630
cellular location: GO:0005829
comment: Reactome DB_ID: 4193818
display name: SMG6

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FZ99
data source: Provenance1
name: Q9FZ99
name: Telomerase-binding protein EST1A
name: EST1A_HUMAN
xref: UnificationXref15400
feature: FragmentFeature4629
cellular location: GO:0005829
comment: Reactome DB_ID: 4193814
display name: SMG6

PPP2R2A(2-447)
type: Protein
entity reference: Q38821
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: PP2A-regulatory subunit B55 alpha isoform
xref: UnificationXref15404
feature: FragmentFeature4631
cellular location: GO:0005829
comment: Reactome DB_ID: 4193800
display name: Q38821

Homologues of PPP2R2A(2-447)
type: Protein
data source: Provenance1
member physical entity: PPP2R2A(2-447)
xref: UnificationXref15407
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4193805

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LHP3
data source: Provenance1
name: Tropoelastin
name: Q9LHP3
name: ELN_HUMAN
xref: UnificationXref15437
feature: FragmentFeature4634
cellular location: GO:0005576
comment: Reactome DB_ID: 4198117
display name: ELN

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O23018
data source: Provenance1
name: Tropoelastin
name: O23018
name: ELN_HUMAN
xref: UnificationXref15439
feature: FragmentFeature4635
cellular location: GO:0005576
comment: Reactome DB_ID: 4198121
display name: ELN

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q6NPS5
data source: Provenance1
name: Tropoelastin
name: Q6NPS5
name: ELN_HUMAN
xref: UnificationXref15441
feature: FragmentFeature4636
cellular location: GO:0005576
comment: Reactome DB_ID: 4198123
display name: ELN

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8L8Q2
data source: Provenance1
name: Q8L8Q2
name: Tropoelastin
name: ELN_HUMAN
xref: UnificationXref15443
feature: FragmentFeature4637
cellular location: GO:0005576
comment: Reactome DB_ID: 4198125
display name: ELN

PPP2R2A(2-447)
type: Protein
entity reference: Q39247
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: PP2A-regulatory subunit B55 alpha isoform
xref: UnificationXref15406
feature: FragmentFeature4632
cellular location: GO:0005829
comment: Reactome DB_ID: 4193804
display name: Q39247

Homologues of ELN
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q9SZD2
xref: UnificationXref15446
cellular location: GO:0005576
comment: Reactome DB_ID: 4198128
comment: Converted from EntitySet in Reactome

Q9SZD2
type: Protein
entity reference: Q9SZD2
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Tropoelastin
name: ELN_HUMAN
xref: UnificationXref15435
feature: FragmentFeature4633
cellular location: GO:0005576
comment: Reactome DB_ID: 4198113
display name: ELN

SequenceSite2689
type: SequenceSite
position status: EQUAL
sequence position: 22

SequenceSite2685
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2686
type: SequenceSite
position status: EQUAL
sequence position: 925

SequenceSite2687
type: SequenceSite
position status: EQUAL
sequence position: 22

THF-polyglutamate
type: SmallMoleculeReference
name: Tetrahydrofolyl-[Glu](n)
name: Tetrahydrofolyl-[Glu](n) [ChEBI:9484]
name: Tetrahydrofolyl-[Glu](n+1)
xref: UnificationXref5666

SequenceSite2688
type: SequenceSite
position status: EQUAL
sequence position: 325

UnificationXref17394
type: UnificationXref
id: B3H5K9
db: UniProt

SequenceSite2673
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17393
type: UnificationXref
id: 4188883
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188883

SequenceSite2672
type: SequenceSite
position status: EQUAL
sequence position: 587

UnificationXref17392
type: UnificationXref
id: Q9FI89
db: UniProt

SequenceSite2671
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17391
type: UnificationXref
id: 4188881
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188881

SequenceSite2670
type: SequenceSite
position status: EQUAL
sequence position: 587

UnificationXref17390
type: UnificationXref
id: B6EUA6
db: UniProt

Fibroblast collagenase
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Intermediate form of Matrix metalloproteinase-1
name: Interstitial collagenase
name: MMP1 intermediate form
name: MMP1(54-469)
xref: UnificationXref15453
feature: FragmentFeature4639
cellular location: GO:0005576
comment: Reactome DB_ID: 4196070
display name: Q9ZUJ5

Homologues of MMP1(54-469)
type: Protein
data source: Provenance1
member physical entity: Fibroblast collagenase
xref: UnificationXref15472
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196080

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:F4JMT8
data source: Provenance1
name: Tropoelastin
name: F4JMT8
name: ELN_HUMAN
xref: UnificationXref15445
feature: FragmentFeature4638
cellular location: GO:0005576
comment: Reactome DB_ID: 4198127
display name: ELN

Fibroblast collagenase
type: Protein
entity reference: O04529
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Intermediate form of Matrix metalloproteinase-1
name: Interstitial collagenase
name: MMP1 intermediate form
name: MMP1(54-469)
xref: UnificationXref15467
feature: FragmentFeature4646
cellular location: GO:0005576
comment: Reactome DB_ID: 4196077
display name: O04529

Fibroblast collagenase
type: Protein
entity reference: O48680
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Intermediate form of Matrix metalloproteinase-1
name: Interstitial collagenase
name: MMP1 intermediate form
name: MMP1(54-469)
xref: UnificationXref15469
feature: FragmentFeature4647
cellular location: GO:0005576
comment: Reactome DB_ID: 4196078
display name: O48680

UniProt:F4JND0
type: ProteinReference
xref: UnificationXref9527
organism: Arabidopsis thaliana

Fibroblast collagenase
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Intermediate form of Matrix metalloproteinase-1
name: Interstitial collagenase
name: MMP1 intermediate form
name: MMP1(54-469)
xref: UnificationXref15463
feature: FragmentFeature4644
cellular location: GO:0005576
comment: Reactome DB_ID: 4196075
display name: Q84W77

Fibroblast collagenase
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Intermediate form of Matrix metalloproteinase-1
name: Interstitial collagenase
name: MMP1 intermediate form
name: MMP1(54-469)
xref: UnificationXref15465
feature: FragmentFeature4645
cellular location: GO:0005576
comment: Reactome DB_ID: 4196076
display name: Q0WVU1

Fibroblast collagenase
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Intermediate form of Matrix metalloproteinase-1
name: Interstitial collagenase
name: MMP1 intermediate form
name: MMP1(54-469)
xref: UnificationXref15459
feature: FragmentFeature4642
cellular location: GO:0005576
comment: Reactome DB_ID: 4196073
display name: Q8LET7

Fibroblast collagenase
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Intermediate form of Matrix metalloproteinase-1
name: Interstitial collagenase
name: MMP1 intermediate form
name: MMP1(54-469)
xref: UnificationXref15461
feature: FragmentFeature4643
cellular location: GO:0005576
comment: Reactome DB_ID: 4196074
display name: Q5XF51

Fibroblast collagenase
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Intermediate form of Matrix metalloproteinase-1
name: Interstitial collagenase
name: MMP1 intermediate form
name: MMP1(54-469)
xref: UnificationXref15455
feature: FragmentFeature4640
cellular location: GO:0005576
comment: Reactome DB_ID: 4196071
display name: O23507

Fibroblast collagenase
type: Protein
entity reference: O65340
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Intermediate form of Matrix metalloproteinase-1
name: Interstitial collagenase
name: MMP1 intermediate form
name: MMP1(54-469)
xref: UnificationXref15457
feature: FragmentFeature4641
cellular location: GO:0005576
comment: Reactome DB_ID: 4196072
display name: O65340

UnificationXref17399
type: UnificationXref
id: 4188924
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188924

SequenceSite2678
type: SequenceSite
position status: EQUAL
sequence position: 925

SequenceSite2679
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17397
type: UnificationXref
id: 4188910
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188910

SequenceSite2676
type: SequenceSite
position status: EQUAL
sequence position: 925

UnificationXref17398
type: UnificationXref
id: 4188917
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188917

SequenceSite2677
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17395
type: UnificationXref
id: 4188885
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188885

SequenceSite2674
type: SequenceSite
position status: EQUAL
sequence position: 587

UnificationXref17396
type: UnificationXref
id: 4188886
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188886

SequenceSite2675
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2660
type: SequenceSite
position status: EQUAL
sequence position: 243

SequenceSite2662
type: SequenceSite
position status: EQUAL
sequence position: 243

SequenceSite2661
type: SequenceSite
position status: EQUAL
sequence position: 1

Homologues of MMP1(84-469)
type: Protein
data source: Provenance1
member physical entity: Fibroblast collagenase
xref: UnificationXref15483
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196000

Fibroblast collagenase
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Intermediate form of Matrix metalloproteinase-1
name: Interstitial collagenase
name: MMP1 intermediate form
name: MMP1(54-469)
xref: UnificationXref15471
feature: FragmentFeature4648
cellular location: GO:0005576
comment: Reactome DB_ID: 4196079
display name: Q8GWW6

Fibroblast collagenase
type: Protein
entity reference: O23507
data source: Provenance1
name: MMP1 42 kDa form
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1(84-469)
name: Matrix metalloproteinase-1
xref: UnificationXref15474
feature: FragmentFeature4650
cellular location: GO:0005576
comment: Reactome DB_ID: 4195991
display name: O23507

Fibroblast collagenase
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP1 42 kDa form
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1(84-469)
name: Matrix metalloproteinase-1
xref: UnificationXref15475
feature: FragmentFeature4651
cellular location: GO:0005576
comment: Reactome DB_ID: 4195992
display name: O65340

Fibroblast collagenase
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: MMP1 42 kDa form
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1(84-469)
name: Matrix metalloproteinase-1
xref: UnificationXref15476
feature: FragmentFeature4652
cellular location: GO:0005576
comment: Reactome DB_ID: 4195993
display name: Q8LET7

Fibroblast collagenase
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP1 42 kDa form
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1(84-469)
name: Matrix metalloproteinase-1
xref: UnificationXref15477
feature: FragmentFeature4653
cellular location: GO:0005576
comment: Reactome DB_ID: 4195994
display name: Q5XF51

Fibroblast collagenase
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP1 42 kDa form
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1(84-469)
name: Matrix metalloproteinase-1
xref: UnificationXref15478
feature: FragmentFeature4654
cellular location: GO:0005576
comment: Reactome DB_ID: 4195995
display name: Q84W77

Fibroblast collagenase
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP1 42 kDa form
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1(84-469)
name: Matrix metalloproteinase-1
xref: UnificationXref15479
feature: FragmentFeature4655
cellular location: GO:0005576
comment: Reactome DB_ID: 4195996
display name: Q0WVU1

Fibroblast collagenase
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP1 42 kDa form
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1(84-469)
name: Matrix metalloproteinase-1
xref: UnificationXref15480
feature: FragmentFeature4656
cellular location: GO:0005576
comment: Reactome DB_ID: 4195997
display name: O04529

Fibroblast collagenase
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP1 42 kDa form
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1(84-469)
name: Matrix metalloproteinase-1
xref: UnificationXref15481
feature: FragmentFeature4657
cellular location: GO:0005576
comment: Reactome DB_ID: 4195998
display name: O48680

SequenceSite2663
type: SequenceSite
position status: EQUAL
sequence position: 1

Procainamide [ChEBI:8428]
type: SmallMoleculeReference
name: Procainamide
xref: UnificationXref17823

SequenceSite2664
type: SequenceSite
position status: EQUAL
sequence position: 243

http://identifiers.org/pubmed/8163052
type: PublicationXref
id: 8163052
author: Gomis, R
author: Malaisse, WJ
author: Sener, A
author: Fernandez-Alvarez, J
author: Conget, I
author: Rasschaert, J
db: Pubmed
title: Enzymatic, metabolic and secretory patterns in human islets of type 2 (non-insulin-dependent) diabetic patients
source: Diabetologia 37:177-81
year: 1994

SequenceSite2665
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2666
type: SequenceSite
position status: EQUAL
sequence position: 243

SequenceSite2667
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2668
type: SequenceSite
position status: EQUAL
sequence position: 243

SequenceSite2669
type: SequenceSite
position status: EQUAL
sequence position: 1

Fibroblast collagenase
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP1 42 kDa form
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1(84-469)
name: Matrix metalloproteinase-1
xref: UnificationXref15473
feature: FragmentFeature4649
cellular location: GO:0005576
comment: Reactome DB_ID: 4195990
display name: Q9ZUJ5

SequenceSite2651
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2650
type: SequenceSite
position status: EQUAL
sequence position: 243

Fibroblast collagenase
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP1 42 kDa form
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1(84-469)
name: Matrix metalloproteinase-1
xref: UnificationXref15482
feature: FragmentFeature4658
cellular location: GO:0005576
comment: Reactome DB_ID: 4195999
display name: Q8GWW6

Fibroblast collagenase
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1 fragment 54-83
name: Matrix metalloproteinase-1
name: MMP1(54-83)
xref: UnificationXref15487
feature: FragmentFeature4662
cellular location: GO:0005576
comment: Reactome DB_ID: 4196278
display name: Q8LET7

Fibroblast collagenase
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1 fragment 54-83
name: Matrix metalloproteinase-1
name: MMP1(54-83)
xref: UnificationXref15488
feature: FragmentFeature4663
cellular location: GO:0005576
comment: Reactome DB_ID: 4196279
display name: Q5XF51

Fibroblast collagenase
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1 fragment 54-83
name: Matrix metalloproteinase-1
name: MMP1(54-83)
xref: UnificationXref15485
feature: FragmentFeature4660
cellular location: GO:0005576
comment: Reactome DB_ID: 4196276
display name: O23507

Fibroblast collagenase
type: Protein
entity reference: O65340
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1 fragment 54-83
name: Matrix metalloproteinase-1
name: MMP1(54-83)
xref: UnificationXref15486
feature: FragmentFeature4661
cellular location: GO:0005576
comment: Reactome DB_ID: 4196277
display name: O65340

Fibroblast collagenase
type: Protein
entity reference: O04529
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1 fragment 54-83
name: Matrix metalloproteinase-1
name: MMP1(54-83)
xref: UnificationXref15491
feature: FragmentFeature4666
cellular location: GO:0005576
comment: Reactome DB_ID: 4196282
display name: O04529

Fibroblast collagenase
type: Protein
entity reference: O48680
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1 fragment 54-83
name: Matrix metalloproteinase-1
name: MMP1(54-83)
xref: UnificationXref15492
feature: FragmentFeature4667
cellular location: GO:0005576
comment: Reactome DB_ID: 4196283
display name: O48680

Fibroblast collagenase
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1 fragment 54-83
name: Matrix metalloproteinase-1
name: MMP1(54-83)
xref: UnificationXref15489
feature: FragmentFeature4664
cellular location: GO:0005576
comment: Reactome DB_ID: 4196280
display name: Q84W77

Fibroblast collagenase
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1 fragment 54-83
name: Matrix metalloproteinase-1
name: MMP1(54-83)
xref: UnificationXref15490
feature: FragmentFeature4665
cellular location: GO:0005576
comment: Reactome DB_ID: 4196281
display name: Q0WVU1

SequenceSite2654
type: SequenceSite
position status: EQUAL
sequence position: 243

SequenceSite2655
type: SequenceSite
position status: EQUAL
sequence position: 1

3-Methyl-2-oxopentanoate
type: SmallMoleculeReference
name: 2-Oxo-3-methylvalerate
name: 3-Methyl-2-oxopentanoate [ChEBI:28654]
xref: UnificationXref6029

SequenceSite2652
type: SequenceSite
position status: EQUAL
sequence position: 243

SequenceSite2653
type: SequenceSite
position status: EQUAL
sequence position: 1

Homologues of MMP1(54-83)
type: Protein
data source: Provenance1
member physical entity: Fibroblast collagenase
xref: UnificationXref15494
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196285

SequenceSite2658
type: SequenceSite
position status: EQUAL
sequence position: 243

Fibroblast collagenase
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Interstitial collagenase
name: MMP1 fragment 54-83
name: Matrix metalloproteinase-1
name: MMP1(54-83)
xref: UnificationXref15484
feature: FragmentFeature4659
cellular location: GO:0005576
comment: Reactome DB_ID: 4196275
display name: Q9ZUJ5

SequenceSite2659
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2656
type: SequenceSite
position status: EQUAL
sequence position: 243

SequenceSite2657
type: SequenceSite
position status: EQUAL
sequence position: 1

Mitotic Prometaphase
type: Pathway
data source: Provenance1
pathway component: REACT 153201.3
evidence: Evidence1255
xref: RelationshipXref1114
xref: UnificationXref13270
xref: UnificationXref13271
pathway order: PathwayStep1235
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/8946167
type: PublicationXref
id: 8946167
author: Blanch, L
author: Anson, D S
author: Hopwood, J J
author: Scott, H S
author: Guo, X H
author: Karageorgos, L E
author: Weber, B
db: Pubmed
title: Structure and sequence of the human sulphamidase gene
source: DNA Res. 3:269-71
year: 1996

http://identifiers.org/pubmed/15720390
type: PublicationXref
id: 15720390
author: Fabre, AL
author: Orlean, P
author: Taron, CH
db: Pubmed
title: Saccharomyces cerevisiae Ybr004c and its human homologue are required for addition of the second mannose during glycosylphosphatidylinositol precursor assembly
source: FEBS J 272:1160-8
year: 2005

UniProt:Q9ZPQ5
type: ProteinReference
xref: UnificationXref1887
organism: Arabidopsis thaliana

UniProt:Q9ZPQ6
type: ProteinReference
xref: UnificationXref1877
organism: Arabidopsis thaliana

UnificationXref17303
type: UnificationXref
id: REACT_102687
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_102687.9

UnificationXref17302
type: UnificationXref
id: 4199371
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199371

UnificationXref17301
type: UnificationXref
id: REACT_81617
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_81617.9

UnificationXref17300
type: UnificationXref
id: 4199574
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199574

http://identifiers.org/pubmed/9199292
type: PublicationXref
id: 9199292
author: Dynlacht, BD
author: Sánchez, I
author: Woo, MS
db: Pubmed
title: p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity
source: Mol Cell Biol 17:3566-79
year: 1997

UnificationXref17309
type: UnificationXref
id: REACT_142433
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_142433.5

UnificationXref17308
type: UnificationXref
id: 4183690
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183690

UnificationXref17307
type: UnificationXref
id: 4183689
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183689

UnificationXref17306
type: UnificationXref
id: 4176766
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4176766

UnificationXref17305
type: UnificationXref
id: REACT_82281
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_82281.9

UnificationXref17304
type: UnificationXref
id: 4199372
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199372

UniProt:Q9ZQ19
type: ProteinReference
xref: UnificationXref11280
organism: Arabidopsis thaliana

UnificationXref17315
type: UnificationXref
id: 4181247
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181247

SequenceSite2715
type: SequenceSite
position status: EQUAL
sequence position: 1144

UnificationXref17316
type: UnificationXref
id: 4183993
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183993

SequenceSite2716
type: SequenceSite
position status: EQUAL
sequence position: 21

UnificationXref17317
type: UnificationXref
id: REACT_130352
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_130352.5

SequenceSite2717
type: SequenceSite
position status: EQUAL
sequence position: 1178

UnificationXref1421
type: UnificationXref
id: 4187898
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187898

UnificationXref17318
type: UnificationXref
id: 4184376
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184376

SequenceSite2718
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1420
type: UnificationXref
id: 4187896
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187896

UnificationXref17319
type: UnificationXref
id: REACT_126480
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_126480.5

SequenceSite2719
type: SequenceSite
position status: EQUAL
sequence position: 726

UnificationXref1423
type: UnificationXref
id: 4199761
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199761

UnificationXref1422
type: UnificationXref
id: REACT_99550
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_99550.9

UnificationXref1425
type: UnificationXref
id: 4199762
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199762

UnificationXref1424
type: UnificationXref
id: REACT_33886
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_33886.10

UnificationXref17310
type: UnificationXref
id: 4184000
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184000

SequenceSite2710
type: SequenceSite
position status: EQUAL
sequence position: 332

UnificationXref17311
type: UnificationXref
id: REACT_126551
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_126551.5

SequenceSite2711
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17312
type: UnificationXref
id: 4183973
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183973

SequenceSite2712
type: SequenceSite
position status: EQUAL
sequence position: 312

UnificationXref17313
type: UnificationXref
id: 4183974
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183974

SequenceSite2713
type: SequenceSite
position status: EQUAL
sequence position: 21

UnificationXref17314
type: UnificationXref
id: Q8L4H0
db: UniProt

SequenceSite2714
type: SequenceSite
position status: EQUAL
sequence position: 1178

UnificationXref1415
type: UnificationXref
id: REACT_14615
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_14615.2

UnificationXref1416
type: UnificationXref
id: CHEBI:17002
db: ChEBI

UnificationXref1417
type: UnificationXref
id: 171076
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=171076

UnificationXref1418
type: UnificationXref
id: REACT_7527
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_7527.2

UnificationXref1419
type: UnificationXref
id: Q9FZI8
db: UniProt

UnificationXref17328
type: UnificationXref
id: REACT_145276
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_145276.5

SequenceSite2728
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1432
type: UnificationXref
id: 30495
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=30495

UnificationXref17329
type: UnificationXref
id: 4199635
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199635

SequenceSite2729
type: SequenceSite
position status: EQUAL
sequence position: 726

UnificationXref1431
type: UnificationXref
id: CHEBI:15904
db: ChEBI

UnificationXref17326
type: UnificationXref
id: 4184374
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184374

SequenceSite2726
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1430
type: UnificationXref
id: REACT_5517
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5517.2

UnificationXref17327
type: UnificationXref
id: 4184375
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184375

SequenceSite2727
type: SequenceSite
position status: EQUAL
sequence position: 726

UnificationXref1436
type: UnificationXref
id: REACT_3756
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3756.1

UnificationXref1435
type: UnificationXref
id: 76116
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=76116

Glycogen breakdown (glycogenolysis)
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction29
pathway component: BiochemicalReaction26
pathway component: BiochemicalReaction27
pathway component: BiochemicalReaction28
evidence: Evidence37
xref: UnificationXref448
xref: RelationshipXref44
xref: UnificationXref449
pathway order: PathwayStep35
pathway order: PathwayStep33
pathway order: PathwayStep34
pathway order: PathwayStep36
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

UnificationXref1434
type: UnificationXref
id: CHEBI:17754
db: ChEBI

UnificationXref1433
type: UnificationXref
id: REACT_4160
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4160.2

UnificationXref17320
type: UnificationXref
id: 4183692
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183692

SequenceSite2720
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/11742412
type: PublicationXref
id: 11742412
author: Saltiel, AR
author: Kahn, CR
db: Pubmed
title: Insulin signalling and the regulation of glucose and lipid metabolism
source: Nature 414:799-806
year: 2001

UnificationXref17321
type: UnificationXref
id: 4183694
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183694

SequenceSite2721
type: SequenceSite
position status: EQUAL
sequence position: 726

UnificationXref17324
type: UnificationXref
id: 4184372
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184372

SequenceSite2724
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17325
type: UnificationXref
id: 4184373
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184373

SequenceSite2725
type: SequenceSite
position status: EQUAL
sequence position: 726

UnificationXref17322
type: UnificationXref
id: 4183696
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183696

SequenceSite2722
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17323
type: UnificationXref
id: 4183697
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183697

SequenceSite2723
type: SequenceSite
position status: EQUAL
sequence position: 726

UnificationXref1428
type: UnificationXref
id: CHEBI:17389
db: ChEBI

UnificationXref1429
type: UnificationXref
id: 163580
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=163580

UnificationXref1426
type: UnificationXref
id: REACT_79237
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_79237.9

UnificationXref1427
type: UnificationXref
id: GO:0005811
db: GENE ONTOLOGY

Acyl chain remodelling of PE
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction188
pathway component: BiochemicalReaction190
pathway component: BiochemicalReaction189
evidence: Evidence261
xref: UnificationXref2721
xref: UnificationXref2720
xref: RelationshipXref309
pathway order: PathwayStep259
pathway order: PathwayStep257
pathway order: PathwayStep258
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

UnificationXref1401
type: UnificationXref
id: 216762
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=216762

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Q0WVU1
name: Stromelysin-1
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15525
feature: FragmentFeature4695
cellular location: GO:0005576
comment: Reactome DB_ID: 4196018
display name: MMP3

UnificationXref1400
type: UnificationXref
id: GO:0030658
db: GENE ONTOLOGY

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: Stromelysin-1
name: O04529
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15526
feature: FragmentFeature4696
cellular location: GO:0005576
comment: Reactome DB_ID: 4196019
display name: MMP3

UnificationXref1403
type: UnificationXref
id: 171095
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=171095

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: Stromelysin-1
name: O48680
name: MMP3_HUMAN
name: Matrix metalloproteinase-3
xref: UnificationXref15527
feature: FragmentFeature4697
cellular location: GO:0005576
comment: Reactome DB_ID: 4196020
display name: MMP3

UnificationXref1402
type: UnificationXref
id: REACT_14189
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_14189.1

UnificationXref17337
type: UnificationXref
id: 4183602
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183602

UnificationXref17338
type: UnificationXref
id: 4183603
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183603

UnificationXref17339
type: UnificationXref
id: 4183595
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183595

UnificationXref17333
type: UnificationXref
id: 4183568
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183568

UnificationXref17334
type: UnificationXref
id: 4183592
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183592

UnificationXref17335
type: UnificationXref
id: 4183593
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183593

UnificationXref17336
type: UnificationXref
id: REACT_145325
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_145325.5

UnificationXref17330
type: UnificationXref
id: REACT_125872
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_125872.5

UnificationXref17331
type: UnificationXref
id: 4199369
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199369

UnificationXref17332
type: UnificationXref
id: REACT_82813
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_82813.9

Synthesis of 12-eicosatetraenoic acid derivatives
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction260
pathway component: BiochemicalReaction258
pathway component: BiochemicalReaction259
evidence: Evidence357
xref: RelationshipXref409
xref: UnificationXref3550
xref: UnificationXref3549
pathway order: PathwayStep354
pathway order: PathwayStep352
pathway order: PathwayStep353
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

UnificationXref1414
type: UnificationXref
id: 194236
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=194236

UnificationXref1413
type: UnificationXref
id: CHEBI:17504
db: ChEBI

SequenceSite2708
type: SequenceSite
position status: EQUAL
sequence position: 332

UnificationXref1412
type: UnificationXref
id: REACT_14183
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_14183.1

SequenceSite2709
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1411
type: UnificationXref
id: 194276
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=194276

http://identifiers.org/pubmed/15274622
type: PublicationXref
id: 15274622
author: Kim, JJ
author: Wang, M
author: Fu, Z
author: Paschke, R
author: Frerman, FE
author: Rao, KS
db: Pubmed
title: Crystal structures of human glutaryl-CoA dehydrogenase with and without an alternate substrate: structural bases of dehydrogenation and decarboxylation reactions
source: Biochemistry 43:9674-84
year: 2004

SequenceSite2706
type: SequenceSite
position status: EQUAL
sequence position: 332

UnificationXref1410
type: UnificationXref
id: CHEBI:16110
db: ChEBI

SequenceSite2707
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17348
type: UnificationXref
id: 4183607
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183607

SequenceSite2704
type: SequenceSite
position status: EQUAL
sequence position: 204

UnificationXref17349
type: UnificationXref
id: 4183609
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183609

SequenceSite2705
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17346
type: UnificationXref
id: REACT_147156
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_147156.5

SequenceSite2702
type: SequenceSite
position status: EQUAL
sequence position: 204

UnificationXref17347
type: UnificationXref
id: 4183606
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183606

SequenceSite2703
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17344
type: UnificationXref
id: 4183599
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183599

SequenceSite2700
type: SequenceSite
position status: EQUAL
sequence position: 311

UnificationXref17345
type: UnificationXref
id: 4183601
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183601

SequenceSite2701
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17342
type: UnificationXref
id: REACT_129252
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_129252.5

UnificationXref17343
type: UnificationXref
id: 4183598
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183598

UnificationXref17340
type: UnificationXref
id: 4183596
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183596

UnificationXref17341
type: UnificationXref
id: 4183604
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183604

UnificationXref1408
type: UnificationXref
id: 4188040
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188040

UnificationXref1409
type: UnificationXref
id: REACT_128359
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_128359.5

UnificationXref1406
type: UnificationXref
id: 4188037
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188037

UnificationXref1407
type: UnificationXref
id: 4188038
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188038

http://identifiers.org/pubmed/15274629
type: PublicationXref
id: 15274629
author: Takeuchi, N
author: Heck, A
author: Spencer, AC
author: Watanabe, K
author: Spremulli, LL
db: Pubmed
title: Characterization of the human mitochondrial methionyl-tRNA synthetase
source: Biochemistry 43:9743-54
year: 2004

UnificationXref1404
type: UnificationXref
id: REACT_7089
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_7089.1

UnificationXref1405
type: UnificationXref
id: Q9ZU35
db: UniProt

UnificationXref1459
type: UnificationXref
id: 4181334
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181334

UniProt:Q9ZPF5
type: ProteinReference
xref: UnificationXref6378
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/20541618
type: PublicationXref
id: 20541618
author: Gilmour, KM
db: Pubmed
title: Perspectives on carbonic anhydrase
source: Comp Biochem Physiol A Mol Integr Physiol 157:193-7
year: 2010

UnificationXref1460
type: UnificationXref
id: Q570J1
db: UniProt

UnificationXref1461
type: UnificationXref
id: 4181336
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181336

UnificationXref1464
type: UnificationXref
id: Q9C522
db: UniProt

UnificationXref1465
type: UnificationXref
id: 4181342
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181342

UnificationXref1462
type: UnificationXref
id: Q42036
db: UniProt

UnificationXref1463
type: UnificationXref
id: 4181340
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181340

UnificationXref1468
type: UnificationXref
id: 4181346
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181346

UnificationXref1469
type: UnificationXref
id: REACT_103402
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_103402.9

UnificationXref1466
type: UnificationXref
id: 4181343
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181343

UnificationXref1467
type: UnificationXref
id: 4181344
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181344

http://identifiers.org/pubmed/8128219
type: PublicationXref
id: 8128219
author: Tonks, N K
author: Flint, A J
author: Barford, D
db: Pubmed
title: Crystal structure of human protein tyrosine phosphatase 1B
source: Science 263:1397-404
year: 1994

UnificationXref1470
type: UnificationXref
id: CHEBI:17544
db: ChEBI

UnificationXref1471
type: UnificationXref
id: 111627
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=111627

UnificationXref1472
type: UnificationXref
id: REACT_4357
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4357.1

UnificationXref1473
type: UnificationXref
id: CHEBI:15531
db: ChEBI

UnificationXref1474
type: UnificationXref
id: 29508
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29508

UnificationXref1475
type: UnificationXref
id: REACT_3059
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3059.1

UnificationXref1476
type: UnificationXref
id: Q0WNF3
db: UniProt

UnificationXref1477
type: UnificationXref
id: MOD:00126
db: MOD

UnificationXref1478
type: UnificationXref
id: 4181364
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181364

UnificationXref1479
type: UnificationXref
id: F4I1L3
db: UniProt

UnificationXref1439
type: UnificationXref
id: Q8LEE3
db: UniProt

UnificationXref1438
type: UnificationXref
id: 4183084
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183084

UnificationXref1437
type: UnificationXref
id: Q94AM5
db: UniProt

http://identifiers.org/pubmed/10681399
type: PublicationXref
id: 10681399
author: Harris, RC
author: Capdevila, JH
author: Falck, JR
db: Pubmed
title: Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase
source: J Lipid Res 41:163-81
year: 2000

UniProt:Q9ZPI1
type: ProteinReference
xref: UnificationXref16638
organism: Arabidopsis thaliana

UniProt:Q9ZPH4
type: ProteinReference
xref: UnificationXref3680
organism: Arabidopsis thaliana

UnificationXref1446
type: UnificationXref
id: 4183096
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183096

UnificationXref1447
type: UnificationXref
id: Q8VYJ0
db: UniProt

UnificationXref1444
type: UnificationXref
id: 4183094
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183094

UnificationXref1445
type: UnificationXref
id: Q9LYG5
db: UniProt

UnificationXref1442
type: UnificationXref
id: 4183092
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183092

UnificationXref1443
type: UnificationXref
id: Q9FX41
db: UniProt

UnificationXref1440
type: UnificationXref
id: 4183088
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183088

UnificationXref1441
type: UnificationXref
id: Q9LPQ4
db: UniProt

Transcription-coupled NER (TC-NER)
type: Pathway
data source: Provenance1
pathway component: REACT 28421.10
pathway component: Resumption of transcription after TC-NER
pathway component: REACT 86892.9
pathway component: REACT 109190.9
evidence: Evidence1038
xref: UnificationXref11391
xref: UnificationXref11390
xref: RelationshipXref1033
pathway order: PathwayStep1024
pathway order: PathwayStep1020
pathway order: PathwayStep1027
pathway order: PathwayStep1026
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

UnificationXref1449
type: UnificationXref
id: 4183099
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183099

UnificationXref1448
type: UnificationXref
id: 4183098
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183098

UnificationXref1450
type: UnificationXref
id: 4183101
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183101

UnificationXref1455
type: UnificationXref
id: REACT_77191
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_77191.9

UnificationXref1456
type: UnificationXref
id: 4181355
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181355

UnificationXref1457
type: UnificationXref
id: REACT_28706
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_28706.10

UnificationXref1458
type: UnificationXref
id: Q9FGX1
db: UniProt

UnificationXref1451
type: UnificationXref
id: REACT_113735
db: Reactome
id version: 8
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_113735.8

UnificationXref1452
type: UnificationXref
id: 4199609
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199609

UnificationXref1453
type: UnificationXref
id: REACT_114503
db: Reactome
id version: 8
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_114503.8

UnificationXref1454
type: UnificationXref
id: 4199610
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199610

UnificationXref1489
type: UnificationXref
id: Q38970
db: UniProt

UnificationXref1488
type: UnificationXref
id: 4181381
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181381

UnificationXref1487
type: UnificationXref
id: Q9C8G1
db: UniProt

UnificationXref1486
type: UnificationXref
id: 4181378
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181378

UnificationXref1485
type: UnificationXref
id: Q38971
db: UniProt

UnificationXref1484
type: UnificationXref
id: 4181375
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181375

UnificationXref1483
type: UnificationXref
id: B3H4A7
db: UniProt

UnificationXref1482
type: UnificationXref
id: 4181372
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181372

UnificationXref1481
type: UnificationXref
id: Q9SKV1
db: UniProt

UnificationXref1480
type: UnificationXref
id: 4181369
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181369

http://identifiers.org/pubmed/9548747
type: PublicationXref
id: 9548747
author: Hammond, PW
author: Cech, TR
db: Pubmed
title: Euplotes telomerase: evidence for limited base-pairing during primer elongation and dGTP as an effector of translocation
source: Biochemistry 37:5162-72
year: 1998

UnificationXref1499
type: UnificationXref
id: REACT_90662
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_90662.9

UnificationXref1496
type: UnificationXref
id: 4181393
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181393

UnificationXref1495
type: UnificationXref
id: P92936
db: UniProt

UnificationXref1498
type: UnificationXref
id: 4186682
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186682

UnificationXref1497
type: UnificationXref
id: 4181394
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181394

UnificationXref1492
type: UnificationXref
id: 4181387
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181387

UnificationXref1491
type: UnificationXref
id: Q9FR96
db: UniProt

UnificationXref1494
type: UnificationXref
id: 4181390
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181390

UnificationXref1493
type: UnificationXref
id: Q7DN91
db: UniProt

UnificationXref1490
type: UnificationXref
id: 4181384
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181384

Stoichiometry2199
type: Stoichiometry
physical entity: Protein6078
stoichiometric coefficient: 2.0

Stoichiometry2198
type: Stoichiometry
physical entity: Complex782
stoichiometric coefficient: 1.0

Stoichiometry2195
type: Stoichiometry
physical entity: Complex776
stoichiometric coefficient: 1.0

Stoichiometry2194
type: Stoichiometry
physical entity: Protein6069
stoichiometric coefficient: 1.0

Stoichiometry2197
type: Stoichiometry
physical entity: PhysicalEntity357
stoichiometric coefficient: 1.0

Stoichiometry2196
type: Stoichiometry
physical entity: Protein6077
stoichiometric coefficient: 1.0

UniProt:Q2V4B9
type: ProteinReference
xref: UnificationXref40
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/18772396
type: PublicationXref
id: 18772396
author: Zhang, X
author: Shinjo, SM
author: Rasheed, BA
author: Lin, JC
author: Carter, H
author: Jones, S
author: Keir, S
author: Parmigiani, G
author: Yan, H
author: McLendon, R
author: Olivi, A
author: Nikolsky, Y
author: Diaz Jr, LA
author: Tekleab, H
author: Vogelstein, B
author: Kinzler, KW
author: Velculescu, VE
author: Papadopoulos, N
author: Mankoo, P
author: Marie, SK
author: Parsons, DW
author: Busam, DA
author: Riggins, GJ
author: Bigner, DD
author: Karchin, R
author: Hartigan, J
author: Angenendt, P
author: Leary, RJ
author: Smith, DR
author: Strausberg, RL
author: Gallia, GL
author: Siu, IM
author: Nikolskaya, T
db: Pubmed
title: An integrated genomic analysis of human glioblastoma multiforme
source: Science 321:1807-12
year: 2008

Stoichiometry2190
type: Stoichiometry
physical entity: PhysicalEntity354
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/17035995
type: PublicationXref
id: 17035995
author: De Camilli, P
author: Di Paolo, G
db: Pubmed
title: Phosphoinositides in cell regulation and membrane dynamics
source: Nature 443:651-7
year: 2006

Stoichiometry2191
type: Stoichiometry
physical entity: Protein6066
stoichiometric coefficient: 1.0

Stoichiometry2192
type: Stoichiometry
physical entity: PhysicalEntity355
stoichiometric coefficient: 1.0

Stoichiometry2193
type: Stoichiometry
physical entity: PhysicalEntity356
stoichiometric coefficient: 1.0

COPI Mediated Transport
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction536
pathway component: BiochemicalReaction535
pathway component: BiochemicalReaction541
pathway component: BiochemicalReaction537
pathway component: BiochemicalReaction540
pathway component: BiochemicalReaction539
pathway component: BiochemicalReaction542
pathway component: BiochemicalReaction538
evidence: Evidence750
xref: UnificationXref7840
xref: RelationshipXref898
xref: UnificationXref7839
pathway order: PathwayStep746
pathway order: PathwayStep741
pathway order: PathwayStep744
pathway order: PathwayStep745
pathway order: PathwayStep743
pathway order: PathwayStep739
pathway order: PathwayStep742
pathway order: PathwayStep740
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

UniProt:F4JKC2
type: ProteinReference
xref: UnificationXref17859
organism: Arabidopsis thaliana

UniProt:F4JKC0
type: ProteinReference
xref: UnificationXref17891
organism: Arabidopsis thaliana

UniProt:F4JKB8
type: ProteinReference
xref: UnificationXref17851
organism: Arabidopsis thaliana

UniProt:F4JKB9
type: ProteinReference
xref: UnificationXref17903
organism: Arabidopsis thaliana

SequenceSite2784
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2785
type: SequenceSite
position status: EQUAL
sequence position: 2458

SequenceSite2786
type: SequenceSite
position status: EQUAL
sequence position: 929

SequenceSite2787
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2788
type: SequenceSite
position status: EQUAL
sequence position: 2458

SequenceSite2789
type: SequenceSite
position status: EQUAL
sequence position: 929

SequenceSite2781
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2780
type: SequenceSite
position status: EQUAL
sequence position: 929

SequenceSite2783
type: SequenceSite
position status: EQUAL
sequence position: 929

SequenceSite2782
type: SequenceSite
position status: EQUAL
sequence position: 2458

SequenceSite2775
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2776
type: SequenceSite
position status: EQUAL
sequence position: 2346

SequenceSite2773
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/9840812
type: PublicationXref
id: 9840812
author: Bradfield, CA
author: Hogenesch, JB
author: Gu, YZ
author: Wartman, L
author: Moran, SM
db: Pubmed
title: Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha
source: Gene Expr 7:205-13
year: 1998

SequenceSite2774
type: SequenceSite
position status: EQUAL
sequence position: 2346

SequenceSite2779
type: SequenceSite
position status: EQUAL
sequence position: 2458

SequenceSite2777
type: SequenceSite
position status: EQUAL
sequence position: 929

SequenceSite2778
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/19416660
type: PublicationXref
id: 19416660
author: Ren, M
author: Xu, Y
author: Malhotra, A
author: Schlame, M
db: Pubmed
title: Formation of molecular species of mitochondrial cardiolipin. 1. A novel transacylation mechanism to shuttle fatty acids between sn-1 and sn-2 positions of multiple phospholipid species
source: Biochim Biophys Acta 1791:314-20
year: 2009

SequenceSite2772
type: SequenceSite
position status: EQUAL
sequence position: 2346

SequenceSite2771
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2770
type: SequenceSite
position status: EQUAL
sequence position: 2346

Homologues of MMP13(55-103)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: O23507
member physical entity: Q8LET7
xref: UnificationXref15860
cellular location: GO:0005576
comment: Reactome DB_ID: 4196470
comment: Converted from EntitySet in Reactome

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Q9ZUJ5
name: MMP13(55-103)
name: Collagenase 3
name: MMP13 fragment 55-103
name: MMP13_HUMAN
xref: UnificationXref15850
feature: FragmentFeature4959
cellular location: GO:0005576
comment: Reactome DB_ID: 4196460
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP13(55-103)
name: Collagenase 3
name: MMP13 fragment 55-103
name: Q84W77
name: MMP13_HUMAN
xref: UnificationXref15855
feature: FragmentFeature4964
cellular location: GO:0005576
comment: Reactome DB_ID: 4196465
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP13(55-103)
name: Q0WVU1
name: Collagenase 3
name: MMP13 fragment 55-103
name: MMP13_HUMAN
xref: UnificationXref15856
feature: FragmentFeature4965
cellular location: GO:0005576
comment: Reactome DB_ID: 4196466
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP13(55-103)
name: O04529
name: Collagenase 3
name: MMP13 fragment 55-103
name: MMP13_HUMAN
xref: UnificationXref15857
feature: FragmentFeature4966
cellular location: GO:0005576
comment: Reactome DB_ID: 4196467
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP13(55-103)
name: Collagenase 3
name: MMP13 fragment 55-103
name: MMP13_HUMAN
name: O48680
xref: UnificationXref15858
feature: FragmentFeature4967
cellular location: GO:0005576
comment: Reactome DB_ID: 4196468
display name: MMP13

http://identifiers.org/pubmed/19487573
type: PublicationXref
id: 19487573
author: Agami, Reuven
author: Rouhanifard, Sara H
author: Holland, Eric C
author: Tuschl, Thomas
author: Huse, Jason T
author: Hambardzumyan, Dolores
author: Brennan, Cameron
author: Sohn-Lee, Cherin
author: le Sage, Carlos
author: Wee, Boyoung
author: Pena, John
db: Pubmed
title: The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo
source: Genes Dev. 23:1327-37
year: 2009

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13(55-103)
name: Collagenase 3
name: MMP13 fragment 55-103
name: MMP13_HUMAN
xref: UnificationXref15851
feature: FragmentFeature4960
cellular location: GO:0005576
comment: Reactome DB_ID: 4196461
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP13(55-103)
name: Collagenase 3
name: O65340
name: MMP13 fragment 55-103
name: MMP13_HUMAN
xref: UnificationXref15852
feature: FragmentFeature4961
cellular location: GO:0005576
comment: Reactome DB_ID: 4196462
display name: MMP13

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13(55-103)
name: Collagenase 3
name: MMP13 fragment 55-103
name: MMP13_HUMAN
xref: UnificationXref15853
feature: FragmentFeature4962
cellular location: GO:0005576
comment: Reactome DB_ID: 4196463
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP13(55-103)
name: Collagenase 3
name: Q5XF51
name: MMP13 fragment 55-103
name: MMP13_HUMAN
xref: UnificationXref15854
feature: FragmentFeature4963
cellular location: GO:0005576
comment: Reactome DB_ID: 4196464
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Q8GWW6
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15848
feature: FragmentFeature4958
cellular location: GO:0005576
comment: Reactome DB_ID: 4196458
display name: MMP13

http://identifiers.org/pubmed/15381398
type: PublicationXref
id: 15381398
author: Jaffe, EK
db: Pubmed
title: The porphobilinogen synthase catalyzed reaction mechanism
source: Bioorg Chem 32:316-25
year: 2004

SequenceSite2799
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2797
type: SequenceSite
position status: EQUAL
sequence position: 2458

SequenceSite2798
type: SequenceSite
position status: EQUAL
sequence position: 929

SequenceSite2795
type: SequenceSite
position status: EQUAL
sequence position: 929

SequenceSite2796
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2794
type: SequenceSite
position status: EQUAL
sequence position: 2458

SequenceSite2793
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2792
type: SequenceSite
position status: EQUAL
sequence position: 929

SequenceSite2791
type: SequenceSite
position status: EQUAL
sequence position: 2458

SequenceSite2790
type: SequenceSite
position status: EQUAL
sequence position: 1

MMP13 intermediate form 58-471
type: Protein
entity reference: O65340
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Collagenase 3
name: O65340
name: MMP13(58-471)
name: MMP13_HUMAN
xref: UnificationXref15829
feature: FragmentFeature4941
cellular location: GO:0005576
comment: Reactome DB_ID: 4196312
display name: MMP13

SequenceSite2749
type: SequenceSite
position status: EQUAL
sequence position: 42

MMP13 intermediate form 58-471
type: Protein
entity reference: O23507
data source: Provenance1
name: O23507
name: Note: the coordinates are copied over from Homo sapiens.
name: Collagenase 3
name: MMP13(58-471)
name: MMP13_HUMAN
xref: UnificationXref15828
feature: FragmentFeature4940
cellular location: GO:0005576
comment: Reactome DB_ID: 4196311
display name: MMP13

SequenceSite2748
type: SequenceSite
position status: EQUAL
sequence position: 681

MMP13 intermediate form 58-471
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Collagenase 3
name: Q5XF51
name: MMP13(58-471)
name: MMP13_HUMAN
xref: UnificationXref15831
feature: FragmentFeature4943
cellular location: GO:0005576
comment: Reactome DB_ID: 4196314
display name: MMP13

MMP13 intermediate form 58-471
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Q8LET7
name: Note: the coordinates are copied over from Homo sapiens.
name: Collagenase 3
name: MMP13(58-471)
name: MMP13_HUMAN
xref: UnificationXref15830
feature: FragmentFeature4942
cellular location: GO:0005576
comment: Reactome DB_ID: 4196313
display name: MMP13

MMP13 intermediate form 58-471
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q0WVU1
name: Collagenase 3
name: MMP13(58-471)
name: MMP13_HUMAN
xref: UnificationXref15833
feature: FragmentFeature4945
cellular location: GO:0005576
comment: Reactome DB_ID: 4196316
display name: MMP13

MMP13 intermediate form 58-471
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Collagenase 3
name: MMP13(58-471)
name: Q84W77
name: MMP13_HUMAN
xref: UnificationXref15832
feature: FragmentFeature4944
cellular location: GO:0005576
comment: Reactome DB_ID: 4196315
display name: MMP13

MMP13 intermediate form 58-471
type: Protein
entity reference: O48680
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Collagenase 3
name: MMP13(58-471)
name: MMP13_HUMAN
name: O48680
xref: UnificationXref15835
feature: FragmentFeature4947
cellular location: GO:0005576
comment: Reactome DB_ID: 4196318
display name: MMP13

MMP13 intermediate form 58-471
type: Protein
entity reference: O04529
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: O04529
name: Collagenase 3
name: MMP13(58-471)
name: MMP13_HUMAN
xref: UnificationXref15834
feature: FragmentFeature4946
cellular location: GO:0005576
comment: Reactome DB_ID: 4196317
display name: MMP13

SequenceSite2741
type: SequenceSite
position status: EQUAL
sequence position: 726

SequenceSite2740
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2743
type: SequenceSite
position status: EQUAL
sequence position: 726

SequenceSite2742
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2745
type: SequenceSite
position status: EQUAL
sequence position: 563

SequenceSite2744
type: SequenceSite
position status: EQUAL
sequence position: 23

SequenceSite2747
type: SequenceSite
position status: EQUAL
sequence position: 725

SequenceSite2746
type: SequenceSite
position status: EQUAL
sequence position: 42

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: Q8GWW6
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15822
feature: FragmentFeature4938
cellular location: GO:0005886
comment: Reactome DB_ID: 4196101
display name: MMP14

Homologues of MMP13(58-471)
type: Protein
data source: Provenance1
member physical entity: MMP13 intermediate form 58-471
xref: UnificationXref15837
cellular location: GO:0005576
comment: Reactome DB_ID: 4196320
comment: Converted from EntitySet in Reactome

MMP13 intermediate form 58-471
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q9ZUJ5
name: Collagenase 3
name: MMP13(58-471)
name: MMP13_HUMAN
xref: UnificationXref15827
feature: FragmentFeature4939
cellular location: GO:0005576
comment: Reactome DB_ID: 4196310
display name: MMP13

http://identifiers.org/pubmed/9188692
type: PublicationXref
id: 9188692
author: Gill, GN
author: Kurten, RC
author: Cadena, DL
db: Pubmed
title: The product of the MLD gene is a member of the membrane fatty acid desaturase family: overexpression of MLD inhibits EGF receptor biosynthesis
source: Biochemistry 36:6960-7
year: 1997

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Collagenase 3
name: Q5XF51
name: MMP13_HUMAN
xref: UnificationXref15843
feature: FragmentFeature4953
cellular location: GO:0005576
comment: Reactome DB_ID: 4196453
display name: MMP13

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15842
feature: FragmentFeature4952
cellular location: GO:0005576
comment: Reactome DB_ID: 4196452
display name: MMP13

SequenceSite2739
type: SequenceSite
position status: EQUAL
sequence position: 726

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: Collagenase 3
name: O65340
name: MMP13_HUMAN
xref: UnificationXref15841
feature: FragmentFeature4951
cellular location: GO:0005576
comment: Reactome DB_ID: 4196451
display name: MMP13

SequenceSite2738
type: SequenceSite
position status: EQUAL
sequence position: 1

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15840
feature: FragmentFeature4950
cellular location: GO:0005576
comment: Reactome DB_ID: 4196450
display name: MMP13

SequenceSite2737
type: SequenceSite
position status: EQUAL
sequence position: 726

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: Collagenase 3
name: MMP13_HUMAN
name: O48680
xref: UnificationXref15847
feature: FragmentFeature4957
cellular location: GO:0005576
comment: Reactome DB_ID: 4196457
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: O04529
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15846
feature: FragmentFeature4956
cellular location: GO:0005576
comment: Reactome DB_ID: 4196456
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Q0WVU1
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15845
feature: FragmentFeature4955
cellular location: GO:0005576
comment: Reactome DB_ID: 4196455
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Collagenase 3
name: Q84W77
name: MMP13_HUMAN
xref: UnificationXref15844
feature: FragmentFeature4954
cellular location: GO:0005576
comment: Reactome DB_ID: 4196454
display name: MMP13

http://identifiers.org/pubmed/8330735
type: PublicationXref
id: 8330735
author: Hernandez, N
db: Pubmed
title: TBP, a universal eukaryotic transcription factor?
source: Genes Dev 7:1291-308
year: 1993

UnificationXref17497
type: UnificationXref
id: 4184387
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184387

SequenceSite2732
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17496
type: UnificationXref
id: 4184386
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184386

SequenceSite2731
type: SequenceSite
position status: EQUAL
sequence position: 726

UnificationXref17495
type: UnificationXref
id: REACT_137341
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_137341.5

SequenceSite2730
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17494
type: UnificationXref
id: 4183972
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183972

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Q9ZUJ5
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15839
feature: FragmentFeature4949
cellular location: GO:0005576
comment: Reactome DB_ID: 4196449
display name: MMP13

SequenceSite2736
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2735
type: SequenceSite
position status: EQUAL
sequence position: 726

UnificationXref17499
type: UnificationXref
id: REACT_127622
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_127622.5

SequenceSite2734
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17498
type: UnificationXref
id: 4184388
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184388

SequenceSite2733
type: SequenceSite
position status: EQUAL
sequence position: 726

UniProt:A4FVN8
type: ProteinReference
xref: UnificationXref8141
organism: Arabidopsis thaliana

UnificationXref17492
type: UnificationXref
id: 4183996
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183996

UnificationXref17493
type: UnificationXref
id: REACT_127797
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_127797.5

UnificationXref17490
type: UnificationXref
id: REACT_94046
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_94046.9

http://identifiers.org/pubmed/8330740
type: PublicationXref
id: 8330740
author: Greider, CW
author: Collins, K
db: Pubmed
title: Tetrahymena telomerase catalyzes nucleolytic cleavage and nonprocessive elongation
source: Genes Dev 7:1364-76
year: 1993

UnificationXref17491
type: UnificationXref
id: 4183971
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183971

MMP13 intermediate form 58-471
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q8GWW6
name: Collagenase 3
name: MMP13(58-471)
name: MMP13_HUMAN
xref: UnificationXref15836
feature: FragmentFeature4948
cellular location: GO:0005576
comment: Reactome DB_ID: 4196319
display name: MMP13

Homologues of MMP13
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: O23507
member physical entity: Q8LET7
xref: UnificationXref15849
cellular location: GO:0005576
comment: Reactome DB_ID: 4196459
comment: Converted from EntitySet in Reactome

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Q0WVU1
name: Collagenase 3
name: MMP13(55-471)
name: MMP13_HUMAN
name: MMP13 intermediate form 55-471
xref: UnificationXref15808
feature: FragmentFeature4925
cellular location: GO:0005576
comment: Reactome DB_ID: 4196432
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Collagenase 3
name: MMP13(55-471)
name: Q84W77
name: MMP13_HUMAN
name: MMP13 intermediate form 55-471
xref: UnificationXref15807
feature: FragmentFeature4924
cellular location: GO:0005576
comment: Reactome DB_ID: 4196431
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: Collagenase 3
name: MMP13(55-471)
name: MMP13_HUMAN
name: O48680
name: MMP13 intermediate form 55-471
xref: UnificationXref15810
feature: FragmentFeature4927
cellular location: GO:0005576
comment: Reactome DB_ID: 4196434
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: O04529
name: Collagenase 3
name: MMP13(55-471)
name: MMP13_HUMAN
name: MMP13 intermediate form 55-471
xref: UnificationXref15809
feature: FragmentFeature4926
cellular location: GO:0005576
comment: Reactome DB_ID: 4196433
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Collagenase 3
name: Q5XF51
name: MMP13(55-471)
name: MMP13_HUMAN
name: MMP13 intermediate form 55-471
xref: UnificationXref15806
feature: FragmentFeature4923
cellular location: GO:0005576
comment: Reactome DB_ID: 4196430
display name: MMP13

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Collagenase 3
name: MMP13(55-471)
name: MMP13_HUMAN
name: MMP13 intermediate form 55-471
xref: UnificationXref15805
feature: FragmentFeature4922
cellular location: GO:0005576
comment: Reactome DB_ID: 4196429
display name: MMP13

UnificationXref17488
type: UnificationXref
id: 4183959
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183959

SequenceSite2767
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17487
type: UnificationXref
id: 4183958
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183958

SequenceSite2766
type: SequenceSite
position status: EQUAL
sequence position: 2346

SequenceSite2769
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17489
type: UnificationXref
id: 4183960
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183960

SequenceSite2768
type: SequenceSite
position status: EQUAL
sequence position: 2346

UnificationXref17484
type: UnificationXref
id: 4183955
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183955

SequenceSite2763
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17483
type: UnificationXref
id: 4183954
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183954

SequenceSite2762
type: SequenceSite
position status: EQUAL
sequence position: 2346

UnificationXref17486
type: UnificationXref
id: 4183957
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183957

SequenceSite2765
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17485
type: UnificationXref
id: 4183956
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183956

SequenceSite2764
type: SequenceSite
position status: EQUAL
sequence position: 2346

UnificationXref17480
type: UnificationXref
id: Q683C9
db: UniProt

UnificationXref17481
type: UnificationXref
id: 4183952
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183952

SequenceSite2760
type: SequenceSite
position status: EQUAL
sequence position: 2346

UnificationXref17482
type: UnificationXref
id: 4183953
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183953

SequenceSite2761
type: SequenceSite
position status: EQUAL
sequence position: 1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: Collagenase 3
name: O65340
name: MMP13(55-471)
name: MMP13_HUMAN
name: MMP13 intermediate form 55-471
xref: UnificationXref15804
feature: FragmentFeature4921
cellular location: GO:0005576
comment: Reactome DB_ID: 4196428
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP13(20-54)
name: MMP13 fragment 20-54
name: Q8GWW6
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15800
feature: FragmentFeature4918
cellular location: GO:0005576
comment: Reactome DB_ID: 4196505
display name: MMP13

Homologues of MMP13(55-471)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q8LET7
member physical entity: O23507
xref: UnificationXref15812
cellular location: GO:0005576
comment: Reactome DB_ID: 4196436
comment: Converted from EntitySet in Reactome

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Q9ZUJ5
name: Collagenase 3
name: MMP13(55-471)
name: MMP13_HUMAN
name: MMP13 intermediate form 55-471
xref: UnificationXref15802
feature: FragmentFeature4919
cellular location: GO:0005576
comment: Reactome DB_ID: 4196426
display name: MMP13

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Collagenase 3
name: MMP13(55-471)
name: MMP13_HUMAN
name: MMP13 intermediate form 55-471
xref: UnificationXref15803
feature: FragmentFeature4920
cellular location: GO:0005576
comment: Reactome DB_ID: 4196427
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: O48680
name: MT1-MMP
xref: UnificationXref15821
feature: FragmentFeature4937
cellular location: GO:0005886
comment: Reactome DB_ID: 4196100
display name: MMP14

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: O04529
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15820
feature: FragmentFeature4936
cellular location: GO:0005886
comment: Reactome DB_ID: 4196099
display name: MMP14

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: Q0WVU1
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15819
feature: FragmentFeature4935
cellular location: GO:0005886
comment: Reactome DB_ID: 4196098
display name: MMP14

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: Matrix metalloproteinase-14
name: Q84W77
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15818
feature: FragmentFeature4934
cellular location: GO:0005886
comment: Reactome DB_ID: 4196097
display name: MMP14

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: Q5XF51
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15817
feature: FragmentFeature4933
cellular location: GO:0005886
comment: Reactome DB_ID: 4196096
display name: MMP14

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Membrane-type-1 matrix metalloproteinase
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15816
feature: FragmentFeature4932
cellular location: GO:0005886
comment: Reactome DB_ID: 4196095
display name: MMP14

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: O65340
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15815
feature: FragmentFeature4931
cellular location: GO:0005886
comment: Reactome DB_ID: 4196094
display name: MMP14

SequenceSite2759
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17479
type: UnificationXref
id: 4183948
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183948

SequenceSite2758
type: SequenceSite
position status: EQUAL
sequence position: 2346

UnificationXref17478
type: UnificationXref
id: Q9M077
db: UniProt

SequenceSite2757
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17477
type: UnificationXref
id: 4183944
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183944

SequenceSite2756
type: SequenceSite
position status: EQUAL
sequence position: 1178

UnificationXref17476
type: UnificationXref
id: O64629
db: UniProt

SequenceSite2755
type: SequenceSite
position status: EQUAL
sequence position: 21

UnificationXref17475
type: UnificationXref
id: REACT_106660
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_106660.9

SequenceSite2754
type: SequenceSite
position status: EQUAL
sequence position: 563

UnificationXref17474
type: UnificationXref
id: 4199639
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199639

SequenceSite2753
type: SequenceSite
position status: EQUAL
sequence position: 23

UnificationXref17473
type: UnificationXref
id: REACT_79089
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_79089.9

SequenceSite2752
type: SequenceSite
position status: EQUAL
sequence position: 725

UnificationXref17472
type: UnificationXref
id: 4183935
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183935

SequenceSite2751
type: SequenceSite
position status: EQUAL
sequence position: 42

UnificationXref17470
type: UnificationXref
id: 4183906
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183906

UnificationXref17471
type: UnificationXref
id: 4183934
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183934

SequenceSite2750
type: SequenceSite
position status: EQUAL
sequence position: 725

http://identifiers.org/pubmed/10648173
type: PublicationXref
id: 10648173
author: Menear, K
author: Baldock, D
author: Graff, P
author: Jones, CE
author: Akhlaq, M
author: Graham, B
db: Pubmed
title: Purification and characterization of human Syk produced using a baculovirus expression system
source: Protein Expr Purif 18:86-94
year: 2000

http://identifiers.org/pubmed/19261456
type: PublicationXref
id: 19261456
author: Procko, E
author: Gaudet, R
db: Pubmed
title: Antigen processing and presentation: TAPping into ABC transporters
source: Curr Opin Immunol 21:84-91
year: 2009

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: Q9ZUJ5
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15813
feature: FragmentFeature4929
cellular location: GO:0005886
comment: Reactome DB_ID: 4196092
display name: MMP14

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Membrane-type-1 matrix metalloproteinase
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15814
feature: FragmentFeature4930
cellular location: GO:0005886
comment: Reactome DB_ID: 4196093
display name: MMP14

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Q8GWW6
name: Collagenase 3
name: MMP13(55-471)
name: MMP13_HUMAN
name: MMP13 intermediate form 55-471
xref: UnificationXref15811
feature: FragmentFeature4928
cellular location: GO:0005576
comment: Reactome DB_ID: 4196435
display name: MMP13

Homologues of MMP14
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q8LET7
member physical entity: O23507
xref: UnificationXref15823
cellular location: GO:0005886
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196102

UnificationXref1518
type: UnificationXref
id: 29768
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29768

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LF46
data source: Provenance1
name: Q8LF46
name: DIM1_HUMAN
name: Spliceosomal U5 snRNP-specific 15 kDa protein
name: Thioredoxin-like U5 snRNP protein U5-15kD
name: DIM1 protein homolog
name: TXNL4A
xref: UnificationXref15980
feature: FragmentFeature5021
cellular location: GO:0005654
comment: Reactome DB_ID: 4178744
display name: DIM1

UnificationXref1519
type: UnificationXref
id: REACT_15656
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15656.2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O82486
data source: Provenance1
name: MT-A70
name: Methyltransferase-like protein 3
name: O82486
name: N6-adenosine-methyltransferase 70 kDa subunit
xref: UnificationXref15973
feature: FragmentFeature5019
cellular location: GO:0005654
comment: Reactome DB_ID: 4177852
display name: METTL3

UnificationXref1514
type: UnificationXref
id: 4181420
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181420

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP16_HUMAN
name: Q8GWW6
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15918
feature: FragmentFeature5018
cellular location: GO:0005886
comment: Reactome DB_ID: 4196559
display name: MMP16

UnificationXref1515
type: UnificationXref
id: 4181422
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181422

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FE62
data source: Provenance1
name: DIM1_HUMAN
name: Spliceosomal U5 snRNP-specific 15 kDa protein
name: Q9FE62
name: Thioredoxin-like U5 snRNP protein U5-15kD
name: DIM1 protein homolog
name: TXNL4A
xref: UnificationXref15978
feature: FragmentFeature5020
cellular location: GO:0005654
comment: Reactome DB_ID: 4178742
display name: DIM1

UnificationXref1516
type: UnificationXref
id: REACT_108413
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_108413.9

Homologues of TXNL4A
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15981
cellular location: GO:0005654
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4178745

UnificationXref1517
type: UnificationXref
id: CHEBI:15843
db: ChEBI

Zinc transporters
type: Pathway
data source: Provenance1
pathway component: REACT 33617.10
pathway component: REACT 130559.5
evidence: Evidence1710
xref: UnificationXref18523
xref: UnificationXref18524
pathway order: PathwayStep1672
pathway order: PathwayStep1679
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

UniProt:F4JL94
type: ProteinReference
xref: UnificationXref6225
organism: Arabidopsis thaliana

UnificationXref17454
type: UnificationXref
id: 4183991
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183991

SequenceSite2810
type: SequenceSite
position status: EQUAL
sequence position: 297

UnificationXref17455
type: UnificationXref
id: 4183998
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183998

SequenceSite2811
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17456
type: UnificationXref
id: REACT_129327
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_129327.5

SequenceSite2812
type: SequenceSite
position status: EQUAL
sequence position: 297

UnificationXref17457
type: UnificationXref
id: 4183992
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183992

SequenceSite2813
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17450
type: UnificationXref
id: REACT_97346
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_97346.9

UnificationXref17451
type: UnificationXref
id: 4183988
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183988

UnificationXref17452
type: UnificationXref
id: 4183989
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183989

UnificationXref17453
type: UnificationXref
id: 4183990
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183990

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q1H595
data source: Provenance1
name: Sm-like protein LSm2
name: U6 snRNA-associated Sm-like protein LSm2
name: Q1H595
name: LSM2
name: SnRNP core SM-like protein SM-x5
name: Small nuclear ribonuclear protein D homolog
xref: UnificationXref15983
feature: FragmentFeature5023
cellular location: GO:0005654
comment: Reactome DB_ID: 4178732
display name: G7b

SequenceSite2818
type: SequenceSite
position status: EQUAL
sequence position: 297

UnificationXref1522
type: UnificationXref
id: REACT_22603
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_22603.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZVT4
data source: Provenance1
name: Sm-like protein LSm2
name: U6 snRNA-associated Sm-like protein LSm2
name: Q9ZVT4
name: LSM2
name: SnRNP core SM-like protein SM-x5
name: Small nuclear ribonuclear protein D homolog
xref: UnificationXref15984
feature: FragmentFeature5024
cellular location: GO:0005654
comment: Reactome DB_ID: 4178734
display name: G7b

SequenceSite2819
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1521
type: UnificationXref
id: 548819
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=548819

Homologues of 2xMe-SNRPB
type: Protein
data source: Provenance1
member physical entity: Protein5967
member physical entity: Protein5968
member physical entity: Protein5970
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Protein5969
member physical entity: Protein5966
xref: UnificationXref15999
cellular location: GO:0005654
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4178293

UnificationXref1524
type: UnificationXref
id: REACT_128000
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_128000.5

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LG45
data source: Provenance1
name: snRNP-B
name: dimethylated Sm Protein B
name: SmB/SmB'
name: Sm-B/Sm-B'
name: Sm protein B/B'
name: 2xMe-SNRPB
name: Small nuclear ribonucleoprotein associated proteins B and B'
xref: UnificationXref15988
feature: ModificationFeature481
feature: FragmentFeature5025
cellular location: GO:0005654
comment: Reactome DB_ID: 4178275
display name: Q8LG45

UnificationXref1523
type: UnificationXref
id: 4192984
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192984

UnificationXref17458
type: UnificationXref
id: REACT_135647
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_135647.5

SequenceSite2814
type: SequenceSite
position status: EQUAL
sequence position: 297

UnificationXref17459
type: UnificationXref
id: 4199650
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199650

SequenceSite2815
type: SequenceSite
position status: EQUAL
sequence position: 1

Homologues of LSM2
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15985
cellular location: GO:0005654
comment: Reactome DB_ID: 4178735
comment: Converted from EntitySet in Reactome

SequenceSite2816
type: SequenceSite
position status: EQUAL
sequence position: 297

UnificationXref1520
type: UnificationXref
id: CHEBI:15514
db: ChEBI

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8L5U6
data source: Provenance1
name: Sm-like protein LSm2
name: U6 snRNA-associated Sm-like protein LSm2
name: LSM2
name: SnRNP core SM-like protein SM-x5
name: Small nuclear ribonuclear protein D homolog
name: Q8L5U6
xref: UnificationXref15982
feature: FragmentFeature5022
cellular location: GO:0005654
comment: Reactome DB_ID: 4178730
display name: G7b

SequenceSite2817
type: SequenceSite
position status: EQUAL
sequence position: 1

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP16_HUMAN
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15912
feature: FragmentFeature5012
cellular location: GO:0005886
comment: Reactome DB_ID: 4196553
display name: MMP16

UnificationXref1529
type: UnificationXref
id: REACT_22457
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_22457.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP16_HUMAN
name: O65340
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15911
feature: FragmentFeature5011
cellular location: GO:0005886
comment: Reactome DB_ID: 4196552
display name: MMP16

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP16_HUMAN
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15910
feature: FragmentFeature5010
cellular location: GO:0005886
comment: Reactome DB_ID: 4196551
display name: MMP16

UnificationXref1527
type: UnificationXref
id: CHEBI:50571
db: ChEBI

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP16_HUMAN
name: Q9ZUJ5
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15909
feature: FragmentFeature5009
cellular location: GO:0005886
comment: Reactome DB_ID: 4196550
display name: MMP16

UnificationXref1528
type: UnificationXref
id: 548812
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=548812

Homologues of MMP16
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: O23507
member physical entity: Q8LET7
xref: UnificationXref15919
cellular location: GO:0005886
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196560

UnificationXref1525
type: UnificationXref
id: 113528
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113528

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP16_HUMAN
name: Q8GWW6
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15906
feature: FragmentFeature5008
cellular location: GO:0005796
comment: Reactome DB_ID: 4196272
display name: MMP16

UnificationXref1526
type: UnificationXref
id: REACT_2373
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2373.1

UnificationXref17460
type: UnificationXref
id: REACT_145991
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_145991.5

UniProt:F4JKY6
type: ProteinReference
xref: UnificationXref3609
organism: Arabidopsis thaliana

UniProt:F4JKY3
type: ProteinReference
xref: UnificationXref3603
organism: Arabidopsis thaliana

UnificationXref17467
type: UnificationXref
id: 4183903
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183903

SequenceSite2823
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17468
type: UnificationXref
id: 4183904
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183904

SequenceSite2824
type: SequenceSite
position status: EQUAL
sequence position: 279

UnificationXref17465
type: UnificationXref
id: 4199645
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199645

SequenceSite2821
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/9949182
type: PublicationXref
id: 9949182
author: Pébusque, MJ
author: Grégoire, MJ
author: Zhang, B
author: Jonveaux, P
author: Popovici, C
author: Lafage-Pochitaloff, M
author: Birnbaum, D
db: Pubmed
title: The t(6;8)(q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to fibroblast growth factor receptor 1
source: Blood 93:1381-9
year: 1999

UnificationXref17466
type: UnificationXref
id: REACT_107735
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_107735.9

SequenceSite2822
type: SequenceSite
position status: EQUAL
sequence position: 279

UnificationXref17463
type: UnificationXref
id: 4199644
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199644

UnificationXref17464
type: UnificationXref
id: REACT_31661
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_31661.10

SequenceSite2820
type: SequenceSite
position status: EQUAL
sequence position: 279

UnificationXref17461
type: UnificationXref
id: 4199643
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199643

UnificationXref17462
type: UnificationXref
id: REACT_128365
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_128365.5

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP16_HUMAN
name: O04529
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15916
feature: FragmentFeature5016
cellular location: GO:0005886
comment: Reactome DB_ID: 4196557
display name: MMP16

UnificationXref1535
type: UnificationXref
id: 4192963
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192963

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP16_HUMAN
name: Matrix metalloproteinase-16
name: O48680
name: MT3-MMP
xref: UnificationXref15917
feature: FragmentFeature5017
cellular location: GO:0005886
comment: Reactome DB_ID: 4196558
display name: MMP16

UnificationXref1534
type: UnificationXref
id: Q9SQU9
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP16_HUMAN
name: Q84W77
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15914
feature: FragmentFeature5014
cellular location: GO:0005886
comment: Reactome DB_ID: 4196555
display name: MMP16

SequenceSite2829
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1533
type: UnificationXref
id: 4192959
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192959

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP16_HUMAN
name: Q0WVU1
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15915
feature: FragmentFeature5015
cellular location: GO:0005886
comment: Reactome DB_ID: 4196556
display name: MMP16

UnificationXref1532
type: UnificationXref
id: Q9SYY4
db: UniProt

http://identifiers.org/pubmed/8250832
type: PublicationXref
id: 8250832
author: Serhan, CN
author: Takahashi, Y
author: Chen, XS
author: Yamamoto, S
author: Romano, M
author: Funk, CD
db: Pubmed
title: Lipoxin synthase activity of human platelet 12-lipoxygenase
source: Biochem J 296:127-33
year: 1993

SequenceSite2827
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1531
type: UnificationXref
id: 4192955
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192955

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP16_HUMAN
name: Q5XF51
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15913
feature: FragmentFeature5013
cellular location: GO:0005886
comment: Reactome DB_ID: 4196554
display name: MMP16

SequenceSite2828
type: SequenceSite
position status: EQUAL
sequence position: 307

UnificationXref1530
type: UnificationXref
id: Q9SQV0
db: UniProt

http://identifiers.org/pubmed/4358634
type: PublicationXref
id: 4358634
author: Roth, DG
author: Deuel, TF
author: Shelton, E
db: Pubmed
title: Purification and properties of phosphoribosyl pyrophosphate synthetase from rat liver
source: J Biol Chem 249:291-296
year: 1974

UnificationXref17469
type: UnificationXref
id: 4183905
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183905

SequenceSite2825
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2826
type: SequenceSite
position status: EQUAL
sequence position: 279

Homologues of MMP16
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q8LET7
member physical entity: O23507
xref: UnificationXref15907
cellular location: GO:0005796
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196273

UnificationXref1536
type: UnificationXref
id: Q9S804
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: Q8GWW6
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15895
feature: FragmentFeature4998
cellular location: GO:0005796
comment: Reactome DB_ID: 4196261
display name: MMP14

UnificationXref1537
type: UnificationXref
id: 4192967
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192967

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP16_HUMAN
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15898
feature: FragmentFeature5000
cellular location: GO:0005796
comment: Reactome DB_ID: 4196264
display name: MMP16

UnificationXref1538
type: UnificationXref
id: 4192968
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192968

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP16_HUMAN
name: Q9ZUJ5
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15897
feature: FragmentFeature4999
cellular location: GO:0005796
comment: Reactome DB_ID: 4196263
display name: MMP16

UnificationXref1539
type: UnificationXref
id: 4192970
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192970

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP16_HUMAN
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15900
feature: FragmentFeature5002
cellular location: GO:0005796
comment: Reactome DB_ID: 4196266
display name: MMP16

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP16_HUMAN
name: O65340
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15899
feature: FragmentFeature5001
cellular location: GO:0005796
comment: Reactome DB_ID: 4196265
display name: MMP16

UniProt:Q5XF06
type: ProteinReference
xref: UnificationXref14721
organism: Arabidopsis thaliana

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP16_HUMAN
name: Q5XF51
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15901
feature: FragmentFeature5003
cellular location: GO:0005796
comment: Reactome DB_ID: 4196267
display name: MMP16

UnificationXref17430
type: UnificationXref
id: 4183705
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183705

SequenceSite2830
type: SequenceSite
position status: EQUAL
sequence position: 307

UnificationXref17431
type: UnificationXref
id: 4183726
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183726

SequenceSite2831
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17432
type: UnificationXref
id: 4183718
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183718

SequenceSite2832
type: SequenceSite
position status: EQUAL
sequence position: 307

UnificationXref17433
type: UnificationXref
id: 4183722
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183722

SequenceSite2833
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17434
type: UnificationXref
id: 4183709
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183709

SequenceSite2834
type: SequenceSite
position status: EQUAL
sequence position: 307

UnificationXref17435
type: UnificationXref
id: 4183713
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183713

SequenceSite2835
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17436
type: UnificationXref
id: 4183714
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183714

SequenceSite2836
type: SequenceSite
position status: EQUAL
sequence position: 252

UnificationXref1540
type: UnificationXref
id: REACT_155569
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_155569.3

UniProt:Q5XF07
type: ProteinReference
xref: UnificationXref10905
organism: Arabidopsis thaliana

UnificationXref17437
type: UnificationXref
id: 4183730
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183730

SequenceSite2837
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17438
type: UnificationXref
id: 4183787
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183787

SequenceSite2838
type: SequenceSite
position status: EQUAL
sequence position: 252

UnificationXref1542
type: UnificationXref
id: 4192978
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192978

UnificationXref17439
type: UnificationXref
id: 4183936
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183936

SequenceSite2839
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1541
type: UnificationXref
id: 4192977
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192977

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP16_HUMAN
name: Q84W77
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15902
feature: FragmentFeature5004
cellular location: GO:0005796
comment: Reactome DB_ID: 4196268
display name: MMP16

UnificationXref1544
type: UnificationXref
id: 4192980
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192980

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP16_HUMAN
name: Q0WVU1
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15903
feature: FragmentFeature5005
cellular location: GO:0005796
comment: Reactome DB_ID: 4196269
display name: MMP16

UnificationXref1543
type: UnificationXref
id: 4192979
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192979

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP16_HUMAN
name: O04529
name: Matrix metalloproteinase-16
name: MT3-MMP
xref: UnificationXref15904
feature: FragmentFeature5006
cellular location: GO:0005796
comment: Reactome DB_ID: 4196270
display name: MMP16

UnificationXref1546
type: UnificationXref
id: 4192983
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192983

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP16_HUMAN
name: Matrix metalloproteinase-16
name: O48680
name: MT3-MMP
xref: UnificationXref15905
feature: FragmentFeature5007
cellular location: GO:0005796
comment: Reactome DB_ID: 4196271
display name: MMP16

UnificationXref1545
type: UnificationXref
id: 4192981
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192981

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Membrane-type-1 matrix metalloproteinase
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15887
feature: FragmentFeature4990
cellular location: GO:0005796
comment: Reactome DB_ID: 4196253
display name: MMP14

UnificationXref1549
type: UnificationXref
id: REACT_22804
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_22804.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: Q9ZUJ5
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15886
feature: FragmentFeature4989
cellular location: GO:0005796
comment: Reactome DB_ID: 4196252
display name: MMP14

Homologues of MMP14
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q8LET7
member physical entity: O23507
xref: UnificationXref15896
cellular location: GO:0005796
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196262

UnificationXref1547
type: UnificationXref
id: CHEBI:50583
db: ChEBI

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Q8GWW6
name: Collagenase 3
name: MMP13_HUMAN
name: MMP13 fragment 77-103
name: MMP13(77-103)
xref: UnificationXref15881
feature: FragmentFeature4988
cellular location: GO:0005576
comment: Reactome DB_ID: 4196491
display name: MMP13

UnificationXref1548
type: UnificationXref
id: 548836
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=548836

Telomere Extension By Telomerase
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction1020
pathway component: BiochemicalReaction1018
pathway component: BiochemicalReaction1017
pathway component: BiochemicalReaction1019
pathway component: BiochemicalReaction1022
pathway component: BiochemicalReaction1021
evidence: Evidence1631
xref: UnificationXref17656
xref: RelationshipXref1353
xref: UnificationXref17655
pathway order: PathwayStep1603
pathway order: PathwayStep1602
pathway order: PathwayStep1604
pathway order: PathwayStep1601
pathway order: PathwayStep1599
pathway order: PathwayStep1600
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: Matrix metalloproteinase-14
name: Q84W77
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15891
feature: FragmentFeature4994
cellular location: GO:0005796
comment: Reactome DB_ID: 4196257
display name: MMP14

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: Q5XF51
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15890
feature: FragmentFeature4993
cellular location: GO:0005796
comment: Reactome DB_ID: 4196256
display name: MMP14

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Membrane-type-1 matrix metalloproteinase
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15889
feature: FragmentFeature4992
cellular location: GO:0005796
comment: Reactome DB_ID: 4196255
display name: MMP14

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: O65340
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15888
feature: FragmentFeature4991
cellular location: GO:0005796
comment: Reactome DB_ID: 4196254
display name: MMP14

UnificationXref17441
type: UnificationXref
id: 4184389
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184389

SequenceSite2841
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17442
type: UnificationXref
id: REACT_140614
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_140614.5

SequenceSite2842
type: SequenceSite
position status: EQUAL
sequence position: 252

UnificationXref17440
type: UnificationXref
id: 4183937
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183937

SequenceSite2840
type: SequenceSite
position status: EQUAL
sequence position: 252

UnificationXref17445
type: UnificationXref
id: 4183940
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183940

SequenceSite2845
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17446
type: UnificationXref
id: REACT_31143
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_31143.10

SequenceSite2846
type: SequenceSite
position status: EQUAL
sequence position: 446

UnificationXref17443
type: UnificationXref
id: 4183788
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183788

SequenceSite2843
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/13679574
type: PublicationXref
id: 13679574
author: Bouvier, M
author: Rousseau, G
author: Angers, S
author: Charest, PG
author: Kohout, T
author: Azzi, M
author: Piñeyro, G
db: Pubmed
title: Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors
source: Proc Natl Acad Sci U S A 100:11406-11
year: 2003

UnificationXref17444
type: UnificationXref
id: 4183938
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183938

SequenceSite2844
type: SequenceSite
position status: EQUAL
sequence position: 706

UnificationXref17449
type: UnificationXref
id: 4199640
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199640

SequenceSite2849
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1553
type: UnificationXref
id: 4192945
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192945

UnificationXref1552
type: UnificationXref
id: Q9FYL6
db: UniProt

UnificationXref17447
type: UnificationXref
id: 4183981
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183981

SequenceSite2847
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1551
type: UnificationXref
id: 4192944
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192944

UnificationXref17448
type: UnificationXref
id: REACT_30026
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_30026.10

SequenceSite2848
type: SequenceSite
position status: EQUAL
sequence position: 446

UnificationXref1550
type: UnificationXref
id: Q8H1N9
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: O04529
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15893
feature: FragmentFeature4996
cellular location: GO:0005796
comment: Reactome DB_ID: 4196259
display name: MMP14

UnificationXref1557
type: UnificationXref
id: 4192947
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192947

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: O48680
name: MT1-MMP
xref: UnificationXref15894
feature: FragmentFeature4997
cellular location: GO:0005796
comment: Reactome DB_ID: 4196260
display name: MMP14

UnificationXref1556
type: UnificationXref
id: O24481
db: UniProt

UnificationXref1555
type: UnificationXref
id: 4192946
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192946

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Membrane-type-1 matrix metalloproteinase
name: Q0WVU1
name: Matrix metalloproteinase-14
name: MMP14_HUMAN
name: MT1-MMP
xref: UnificationXref15892
feature: FragmentFeature4995
cellular location: GO:0005796
comment: Reactome DB_ID: 4196258
display name: MMP14

UnificationXref1554
type: UnificationXref
id: Q8L9C4
db: UniProt

http://identifiers.org/pubmed/8131753
type: PublicationXref
id: 8131753
author: Lieber, MR
author: Harrington, JJ
db: Pubmed
title: The characterization of a mammalian DNA structure-specific endonuclease.
source: EMBO J 13:1235-46
year: 1994

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Q0WVU1
name: Collagenase 3
name: MMP13_HUMAN
name: MMP13 fragment 77-103
name: MMP13(77-103)
xref: UnificationXref15878
feature: FragmentFeature4985
cellular location: GO:0005576
comment: Reactome DB_ID: 4196488
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: Collagenase 3
name: O65340
name: MMP13_HUMAN
name: MMP13 fragment 77-103
name: MMP13(77-103)
xref: UnificationXref15874
feature: FragmentFeature4981
cellular location: GO:0005576
comment: Reactome DB_ID: 4196484
display name: MMP13

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Collagenase 3
name: MMP13_HUMAN
name: MMP13 fragment 77-103
name: MMP13(77-103)
xref: UnificationXref15875
feature: FragmentFeature4982
cellular location: GO:0005576
comment: Reactome DB_ID: 4196485
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Collagenase 3
name: Q5XF51
name: MMP13_HUMAN
name: MMP13 fragment 77-103
name: MMP13(77-103)
xref: UnificationXref15876
feature: FragmentFeature4983
cellular location: GO:0005576
comment: Reactome DB_ID: 4196486
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Collagenase 3
name: Q84W77
name: MMP13_HUMAN
name: MMP13 fragment 77-103
name: MMP13(77-103)
xref: UnificationXref15877
feature: FragmentFeature4984
cellular location: GO:0005576
comment: Reactome DB_ID: 4196487
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP13 fragment 58-103
name: Q8GWW6
name: Collagenase 3
name: MMP13(58-103)
name: MMP13_HUMAN
xref: UnificationXref15870
feature: FragmentFeature4978
cellular location: GO:0005576
comment: Reactome DB_ID: 4196480
display name: MMP13

Homologues of MMP13(77-103)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q8LET7
member physical entity: O23507
xref: UnificationXref15882
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196492

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Q9ZUJ5
name: Collagenase 3
name: MMP13_HUMAN
name: MMP13 fragment 77-103
name: MMP13(77-103)
xref: UnificationXref15872
feature: FragmentFeature4979
cellular location: GO:0005576
comment: Reactome DB_ID: 4196482
display name: MMP13

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Collagenase 3
name: MMP13_HUMAN
name: MMP13 fragment 77-103
name: MMP13(77-103)
xref: UnificationXref15873
feature: FragmentFeature4980
cellular location: GO:0005576
comment: Reactome DB_ID: 4196483
display name: MMP13

UnificationXref17419
type: UnificationXref
id: 4183748
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183748

UnificationXref17418
type: UnificationXref
id: 4183744
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183744

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: Collagenase 3
name: MMP13_HUMAN
name: MMP13 fragment 77-103
name: O48680
name: MMP13(77-103)
xref: UnificationXref15880
feature: FragmentFeature4987
cellular location: GO:0005576
comment: Reactome DB_ID: 4196490
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: O04529
name: Collagenase 3
name: MMP13_HUMAN
name: MMP13 fragment 77-103
name: MMP13(77-103)
xref: UnificationXref15879
feature: FragmentFeature4986
cellular location: GO:0005576
comment: Reactome DB_ID: 4196489
display name: MMP13

UnificationXref17415
type: UnificationXref
id: 4183739
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183739

UnificationXref17414
type: UnificationXref
id: 4183753
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183753

UnificationXref17417
type: UnificationXref
id: 4183738
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183738

UnificationXref17416
type: UnificationXref
id: 4183734
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183734

UnificationXref17411
type: UnificationXref
id: REACT_114960
db: Reactome
id version: 8
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_114960.8

UnificationXref17410
type: UnificationXref
id: 4199633
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199633

UnificationXref17413
type: UnificationXref
id: 4183740
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183740

UnificationXref17412
type: UnificationXref
id: 4183701
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183701

http://identifiers.org/pubmed/9883897
type: PublicationXref
id: 9883897
author: Csere, P
author: Lill, R
author: Kispal, G
db: Pubmed
title: Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p
source: FEBS Lett 441:266-70
year: 1998

Stoichiometry2204
type: Stoichiometry
physical entity: Protein2624
stoichiometric coefficient: 1.0

Stoichiometry2205
type: Stoichiometry
physical entity: PhysicalEntity360
stoichiometric coefficient: 1.0

Stoichiometry2202
type: Stoichiometry
physical entity: PhysicalEntity358
stoichiometric coefficient: 1.0

Stoichiometry2203
type: Stoichiometry
physical entity: PhysicalEntity359
stoichiometric coefficient: 1.0

Stoichiometry2208
type: Stoichiometry
physical entity: Protein6118
stoichiometric coefficient: 1.0

Stoichiometry2209
type: Stoichiometry
physical entity: Protein2534
stoichiometric coefficient: 1.0

Stoichiometry2206
type: Stoichiometry
physical entity: Protein6088
stoichiometric coefficient: 1.0

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP13 fragment 58-103
name: Q0WVU1
name: Collagenase 3
name: MMP13(58-103)
name: MMP13_HUMAN
xref: UnificationXref15867
feature: FragmentFeature4975
cellular location: GO:0005576
comment: Reactome DB_ID: 4196477
display name: MMP13

Stoichiometry2207
type: Stoichiometry
physical entity: Protein2515
stoichiometric coefficient: 1.0

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP13 fragment 58-103
name: O04529
name: Collagenase 3
name: MMP13(58-103)
name: MMP13_HUMAN
xref: UnificationXref15868
feature: FragmentFeature4976
cellular location: GO:0005576
comment: Reactome DB_ID: 4196478
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP13 fragment 58-103
name: Collagenase 3
name: MMP13(58-103)
name: Q5XF51
name: MMP13_HUMAN
xref: UnificationXref15865
feature: FragmentFeature4973
cellular location: GO:0005576
comment: Reactome DB_ID: 4196475
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP13 fragment 58-103
name: Collagenase 3
name: MMP13(58-103)
name: Q84W77
name: MMP13_HUMAN
xref: UnificationXref15866
feature: FragmentFeature4974
cellular location: GO:0005576
comment: Reactome DB_ID: 4196476
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP13 fragment 58-103
name: Collagenase 3
name: MMP13(58-103)
name: O65340
name: MMP13_HUMAN
xref: UnificationXref15863
feature: FragmentFeature4971
cellular location: GO:0005576
comment: Reactome DB_ID: 4196473
display name: MMP13

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13 fragment 58-103
name: Collagenase 3
name: MMP13(58-103)
name: MMP13_HUMAN
xref: UnificationXref15864
feature: FragmentFeature4972
cellular location: GO:0005576
comment: Reactome DB_ID: 4196474
display name: MMP13

Stoichiometry2200
type: Stoichiometry
physical entity: Protein6084
stoichiometric coefficient: 1.0

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP13 fragment 58-103
name: Q9ZUJ5
name: Collagenase 3
name: MMP13(58-103)
name: MMP13_HUMAN
xref: UnificationXref15861
feature: FragmentFeature4969
cellular location: GO:0005576
comment: Reactome DB_ID: 4196471
display name: MMP13

Stoichiometry2201
type: Stoichiometry
physical entity: Protein2594
stoichiometric coefficient: 1.0

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13 fragment 58-103
name: Collagenase 3
name: MMP13(58-103)
name: MMP13_HUMAN
xref: UnificationXref15862
feature: FragmentFeature4970
cellular location: GO:0005576
comment: Reactome DB_ID: 4196472
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Q8GWW6
name: MMP13(55-103)
name: Collagenase 3
name: MMP13 fragment 55-103
name: MMP13_HUMAN
xref: UnificationXref15859
feature: FragmentFeature4968
cellular location: GO:0005576
comment: Reactome DB_ID: 4196469
display name: MMP13

Homologues of MMP13(58-103)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q8LET7
member physical entity: O23507
xref: UnificationXref15871
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196481

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP13 fragment 58-103
name: Collagenase 3
name: MMP13(58-103)
name: MMP13_HUMAN
name: O48680
xref: UnificationXref15869
feature: FragmentFeature4977
cellular location: GO:0005576
comment: Reactome DB_ID: 4196479
display name: MMP13

UnificationXref17429
type: UnificationXref
id: 4183786
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183786

UnificationXref17428
type: UnificationXref
id: 4183785
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183785

UnificationXref17427
type: UnificationXref
id: 4183781
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183781

UnificationXref17426
type: UnificationXref
id: 4183777
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183777

UnificationXref17425
type: UnificationXref
id: 4183773
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183773

UnificationXref17424
type: UnificationXref
id: 4183769
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183769

UnificationXref17423
type: UnificationXref
id: 4183765
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183765

UnificationXref17422
type: UnificationXref
id: 4183761
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183761

UnificationXref17421
type: UnificationXref
id: 4183757
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183757

UnificationXref17420
type: UnificationXref
id: 4183749
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183749

Stoichiometry2217
type: Stoichiometry
physical entity: Protein6221
stoichiometric coefficient: 1.0

Stoichiometry2218
type: Stoichiometry
physical entity: PhysicalEntity362
stoichiometric coefficient: 1.0

Stoichiometry2219
type: Stoichiometry
physical entity: Protein2598
stoichiometric coefficient: 1.0

Stoichiometry2213
type: Stoichiometry
physical entity: PhysicalEntity65
stoichiometric coefficient: 1.0

Stoichiometry2214
type: Stoichiometry
physical entity: PhysicalEntity361
stoichiometric coefficient: 1.0

Stoichiometry2215
type: Stoichiometry
physical entity: Protein6185
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/14530973
type: PublicationXref
id: 14530973
author: Mackenzie, B
author: Hediger, MA
db: Pubmed
title: SLC11 family of H+-coupled metal-ion transporters NRAMP1 and DMT1
source: Pflugers Arch 447:571-9
year: 2004

Stoichiometry2216
type: Stoichiometry
physical entity: Protein6215
stoichiometric coefficient: 1.0

Stoichiometry2210
type: Stoichiometry
physical entity: Protein2564
stoichiometric coefficient: 1.0

Stoichiometry2211
type: Stoichiometry
physical entity: Protein6122
stoichiometric coefficient: 1.0

Stoichiometry2212
type: Stoichiometry
physical entity: Protein6152
stoichiometric coefficient: 1.0

PublicationXref76
type: PublicationXref
author: Hers, HG
title: Triokinases
source: The Enzymes, 2nd ed (Boyer PD, Lardy H, Myrback K, editors) 6:75-83
year: 1962

UnificationXref1500
type: UnificationXref
id: 4186683
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186683

PublicationXref75
type: PublicationXref
author: Gitzelmann, R
author: Steinmann, B
author: Van den Berghe, G
title: Disorders of fructose metabolism
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Scriver CR, et al., editors) 1:1489-1520
year: 2001

UnificationXref1501
type: UnificationXref
id: GO:0005769
db: GENE ONTOLOGY

UnificationXref1502
type: UnificationXref
id: CHEBI:15756
db: ChEBI

Conversion of palmitic acid to very long chain fatty acyl-CoAs
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction109
pathway component: BiochemicalReaction105
pathway component: BiochemicalReaction108
pathway component: BiochemicalReaction106
pathway component: BiochemicalReaction104
pathway component: BiochemicalReaction107
evidence: Evidence145
xref: UnificationXref1573
xref: UnificationXref1574
xref: RelationshipXref183
pathway order: PathwayStep143
pathway order: PathwayStep142
pathway order: PathwayStep139
pathway order: PathwayStep141
pathway order: PathwayStep140
pathway order: PathwayStep144
display name: Synthesis of very long-chain fatty acyl-CoAs
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Stoichiometry2228
type: Stoichiometry
physical entity: Protein6266
stoichiometric coefficient: 1.0

Stoichiometry2229
type: Stoichiometry
physical entity: Protein6269
stoichiometric coefficient: 1.0

Stoichiometry2226
type: Stoichiometry
physical entity: Complex781
stoichiometric coefficient: 1.0

Stoichiometry2227
type: Stoichiometry
physical entity: Protein6265
stoichiometric coefficient: 1.0

Stoichiometry2224
type: Stoichiometry
physical entity: Protein6261
stoichiometric coefficient: 1.0

Stoichiometry2225
type: Stoichiometry
physical entity: Complex772
stoichiometric coefficient: 1.0

Stoichiometry2222
type: Stoichiometry
physical entity: Protein2539
stoichiometric coefficient: 1.0

UnificationXref1506
type: UnificationXref
id: 200993
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=200993

Stoichiometry2223
type: Stoichiometry
physical entity: Protein2554
stoichiometric coefficient: 1.0

UnificationXref1505
type: UnificationXref
id: CHEBI:15525
db: ChEBI

PublicationXref78
type: PublicationXref
author: Tyfield, LA
author: Walter, JH
author: Holton, JB
title: Galactosemia
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Scriver CR, et al., editors) 1:1553-1587
year: 2001

Stoichiometry2220
type: Stoichiometry
physical entity: Protein6226
stoichiometric coefficient: 1.0

UnificationXref1504
type: UnificationXref
id: REACT_3374
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3374.3

Stoichiometry2221
type: Stoichiometry
physical entity: Protein6256
stoichiometric coefficient: 1.0

UnificationXref1503
type: UnificationXref
id: 76168
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=76168

UnificationXref1509
type: UnificationXref
id: Q9CAP8
db: UniProt

UnificationXref1508
type: UnificationXref
id: GO:0005789
db: GENE ONTOLOGY

UnificationXref1507
type: UnificationXref
id: REACT_11391
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_11391.2

UnificationXref17406
type: UnificationXref
id: 4199788
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199788

SequenceSite2806
type: SequenceSite
position status: EQUAL
sequence position: 2458

http://identifiers.org/pubmed/9331217
type: PublicationXref
id: 9331217
author: Cooper, JA
author: Hart, MC
author: Korshunova, YO
db: Pubmed
title: Vertebrates have conserved capping protein alpha isoforms with specific expression patterns
source: Cell Motil Cytoskeleton 38:120-32
year: 1997

UnificationXref17405
type: UnificationXref
id: REACT_155377
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_155377.3

SequenceSite2805
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17404
type: UnificationXref
id: 4199787
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199787

SequenceSite2804
type: SequenceSite
position status: EQUAL
sequence position: 929

UnificationXref17403
type: UnificationXref
id: REACT_158414
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_158414.3

SequenceSite2803
type: SequenceSite
position status: EQUAL
sequence position: 2458

UnificationXref1512
type: UnificationXref
id: 4181418
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181418

UnificationXref17409
type: UnificationXref
id: REACT_114616
db: Reactome
id version: 8
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_114616.8

SequenceSite2809
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1513
type: UnificationXref
id: 4181419
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181419

UnificationXref17408
type: UnificationXref
id: 4199632
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199632

SequenceSite2808
type: SequenceSite
position status: EQUAL
sequence position: 297

UnificationXref1510
type: UnificationXref
id: 4181414
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181414

UnificationXref17407
type: UnificationXref
id: REACT_157899
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_157899.3

SequenceSite2807
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1511
type: UnificationXref
id: Q9SJD4
db: UniProt

UnificationXref17402
type: UnificationXref
id: 4199786
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199786

SequenceSite2802
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17401
type: UnificationXref
id: REACT_158419
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_158419.3

SequenceSite2801
type: SequenceSite
position status: EQUAL
sequence position: 929

UnificationXref17400
type: UnificationXref
id: 4188925
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188925

SequenceSite2800
type: SequenceSite
position status: EQUAL
sequence position: 2458

Stoichiometry2230
type: Stoichiometry
physical entity: Protein6272
stoichiometric coefficient: 1.0

Stoichiometry2234
type: Stoichiometry
physical entity: Complex776
stoichiometric coefficient: 1.0

Stoichiometry2233
type: Stoichiometry
physical entity: Protein6276
stoichiometric coefficient: 1.0

Stoichiometry2232
type: Stoichiometry
physical entity: Protein6273
stoichiometric coefficient: 1.0

Stoichiometry2231
type: Stoichiometry
physical entity: Complex784
stoichiometric coefficient: 1.0

Stoichiometry2238
type: Stoichiometry
physical entity: Protein6287
stoichiometric coefficient: 1.0

Stoichiometry2237
type: Stoichiometry
physical entity: Protein6284
stoichiometric coefficient: 1.0

Stoichiometry2236
type: Stoichiometry
physical entity: Protein6273
stoichiometric coefficient: 1.0

Stoichiometry2235
type: Stoichiometry
physical entity: PhysicalEntity363
stoichiometric coefficient: 1.0

Stoichiometry2239
type: Stoichiometry
physical entity: PhysicalEntity364
stoichiometric coefficient: 1.0

Stoichiometry2241
type: Stoichiometry
physical entity: Complex785
stoichiometric coefficient: 1.0

Stoichiometry2240
type: Stoichiometry
physical entity: Protein6291
stoichiometric coefficient: 1.0

Stoichiometry2243
type: Stoichiometry
physical entity: Protein6296
stoichiometric coefficient: 1.0

Stoichiometry2242
type: Stoichiometry
physical entity: Protein6295
stoichiometric coefficient: 1.0

Stoichiometry2245
type: Stoichiometry
physical entity: Complex775
stoichiometric coefficient: 1.0

Stoichiometry2244
type: Stoichiometry
physical entity: Complex783
stoichiometric coefficient: 1.0

Stoichiometry2247
type: Stoichiometry
physical entity: Complex777
stoichiometric coefficient: 1.0

Stoichiometry2246
type: Stoichiometry
physical entity: Complex780
stoichiometric coefficient: 1.0

Stoichiometry2249
type: Stoichiometry
physical entity: Protein6299
stoichiometric coefficient: 1.0

Stoichiometry2248
type: Stoichiometry
physical entity: PhysicalEntity365
stoichiometric coefficient: 1.0

PublicationXref30
type: PublicationXref
id: 0121227022
author: Noltmann, EA
db: ISBN
title: Aldose-ketose isomerases
source: The Enzymes, 3rd ed (Book): 271-354
year: 1972

Stoichiometry2256
type: Stoichiometry
physical entity: Protein2602
stoichiometric coefficient: 1.0

Stoichiometry2255
type: Stoichiometry
physical entity: Protein2524
stoichiometric coefficient: 1.0

Stoichiometry2254
type: Stoichiometry
physical entity: Complex366
stoichiometric coefficient: 1.0

Stoichiometry2253
type: Stoichiometry
physical entity: Complex358
stoichiometric coefficient: 1.0

Stoichiometry2252
type: Stoichiometry
physical entity: Complex788
stoichiometric coefficient: 1.0

Stoichiometry2251
type: Stoichiometry
physical entity: PhysicalEntity367
stoichiometric coefficient: 1.0

Stoichiometry2250
type: Stoichiometry
physical entity: PhysicalEntity366
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/15665109
type: PublicationXref
id: 15665109
author: Dirago, L
author: Mifsud, S
author: Hyland, C
author: Alexander, WS
author: Hilton, DJ
author: Carpinelli, MR
author: Nicola, NA
author: Metcalf, D
db: Pubmed
title: Anomalous megakaryocytopoiesis in mice with mutations in the c-Myb gene
source: Blood 105:3480-7
year: 2005

Stoichiometry2259
type: Stoichiometry
physical entity: Complex789
stoichiometric coefficient: 1.0

Stoichiometry2258
type: Stoichiometry
physical entity: Protein6306
stoichiometric coefficient: 1.0

Stoichiometry2257
type: Stoichiometry
physical entity: Protein6303
stoichiometric coefficient: 1.0

Stoichiometry2265
type: Stoichiometry
physical entity: Protein6122
stoichiometric coefficient: 1.0

Stoichiometry2264
type: Stoichiometry
physical entity: PhysicalEntity353
stoichiometric coefficient: 1.0

Stoichiometry2267
type: Stoichiometry
physical entity: PhysicalEntity349
stoichiometric coefficient: 1.0

Stoichiometry2266
type: Stoichiometry
physical entity: Protein6066
stoichiometric coefficient: 1.0

PublicationXref33
type: PublicationXref
id: 0121227022
author: Lardy, HA
author: Bloxham, DP
db: ISBN
title: Phosphofructokinase
source: The Enzymes, 3rd ed (Book): 239-278
year: 1973

Stoichiometry2261
type: Stoichiometry
physical entity: Protein6034
stoichiometric coefficient: 1.0

Stoichiometry2260
type: Stoichiometry
physical entity: Protein6030
stoichiometric coefficient: 1.0

Stoichiometry2263
type: Stoichiometry
physical entity: PhysicalEntity344
stoichiometric coefficient: 1.0

Stoichiometry2262
type: Stoichiometry
physical entity: PhysicalEntity348
stoichiometric coefficient: 1.0

Stoichiometry2269
type: Stoichiometry
physical entity: Protein6078
stoichiometric coefficient: 2.0

Stoichiometry2268
type: Stoichiometry
physical entity: Protein6152
stoichiometric coefficient: 1.0

UnificationXref1567
type: UnificationXref
id: 428139
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=428139

UnificationXref1568
type: UnificationXref
id: REACT_20205
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_20205.3

UnificationXref1565
type: UnificationXref
id: REACT_22862
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_22862.1

UnificationXref1566
type: UnificationXref
id: CHEBI:15541
db: ChEBI

Stoichiometry2270
type: Stoichiometry
physical entity: Protein6185
stoichiometric coefficient: 1.0

UnificationXref1563
type: UnificationXref
id: CHEBI:50570
db: ChEBI

UnificationXref1564
type: UnificationXref
id: 548809
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=548809

UnificationXref1561
type: UnificationXref
id: 4192951
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192951

UnificationXref1562
type: UnificationXref
id: REACT_141593
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_141593.5

UnificationXref1560
type: UnificationXref
id: 4192949
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192949

Stoichiometry2279
type: Stoichiometry
physical entity: Complex778
stoichiometric coefficient: 1.0

Stoichiometry2273
type: Stoichiometry
physical entity: PhysicalEntity362
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/224930
type: PublicationXref
id: 224930
author: Inoue, K
author: Yamasawa, K
author: Nishimukai, H
db: Pubmed
title: Purification and partial characterization of aldehyde dehydrogenase from human erythrocytes.
source: Biochim Biophys Acta 569:117-23
year: 1979

Stoichiometry2274
type: Stoichiometry
physical entity: Protein6226
stoichiometric coefficient: 1.0

Stoichiometry2271
type: Stoichiometry
physical entity: Protein6215
stoichiometric coefficient: 1.0

Stoichiometry2272
type: Stoichiometry
physical entity: Protein6065
stoichiometric coefficient: 1.0

Stoichiometry2277
type: Stoichiometry
physical entity: Protein6088
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/18436705
type: PublicationXref
id: 18436705
author: Scheuner, D
author: Kaufman, RJ
db: Pubmed
title: The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes
source: Endocr Rev 29:317-33
year: 2008

Stoichiometry2278
type: Stoichiometry
physical entity: Complex791
stoichiometric coefficient: 1.0

Stoichiometry2275
type: Stoichiometry
physical entity: PhysicalEntity359
stoichiometric coefficient: 1.0

UnificationXref1559
type: UnificationXref
id: 4192948
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192948

Stoichiometry2276
type: Stoichiometry
physical entity: PhysicalEntity347
stoichiometric coefficient: 1.0

UnificationXref1558
type: UnificationXref
id: Q9AST7
db: UniProt

UnificationXref1576
type: UnificationXref
id: REACT_78691
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_78691.9

UnificationXref1577
type: UnificationXref
id: CHEBI:15978
db: ChEBI

UnificationXref1578
type: UnificationXref
id: 76114
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=76114

UnificationXref1579
type: UnificationXref
id: REACT_4327
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4327.2

UnificationXref1572
type: UnificationXref
id: REACT_130473
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_130473.5

UnificationXref1573
type: UnificationXref
id: 4199513
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199513

Stoichiometry2281
type: Stoichiometry
physical entity: Protein2506
stoichiometric coefficient: 1.0

UnificationXref1574
type: UnificationXref
id: REACT_84277
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_84277.9

Stoichiometry2280
type: Stoichiometry
physical entity: Protein6064
stoichiometric coefficient: 1.0

UnificationXref1575
type: UnificationXref
id: 4199505
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199505

UnificationXref1570
type: UnificationXref
id: 4192974
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192974

UnificationXref1571
type: UnificationXref
id: 4192976
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192976

http://identifiers.org/pubmed/8647822
type: PublicationXref
id: 8647822
author: Sanchez, HB
author: Osborne, TF
author: Rosenfeld, JM
author: Vallett, SM
db: Pubmed
title: A direct role for sterol regulatory element binding protein in activation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene
source: J Biol Chem 271:12247-53
year: 1996

Stoichiometry2282
type: Stoichiometry
physical entity: PhysicalEntity62
stoichiometric coefficient: 1.0

Stoichiometry2283
type: Stoichiometry
physical entity: PhysicalEntity345
stoichiometric coefficient: 1.0

Stoichiometry2284
type: Stoichiometry
physical entity: PhysicalEntity66
stoichiometric coefficient: 1.0

Stoichiometry2285
type: Stoichiometry
physical entity: PhysicalEntity355
stoichiometric coefficient: 1.0

Stoichiometry2286
type: Stoichiometry
physical entity: PhysicalEntity343
stoichiometric coefficient: 1.0

Stoichiometry2287
type: Stoichiometry
physical entity: Protein6084
stoichiometric coefficient: 1.0

UnificationXref1569
type: UnificationXref
id: Q9M2U2
db: UniProt

Stoichiometry2288
type: Stoichiometry
physical entity: Protein2576
stoichiometric coefficient: 1.0

Stoichiometry2289
type: Stoichiometry
physical entity: Complex775
stoichiometric coefficient: 1.0

Stoichiometry2292
type: Stoichiometry
physical entity: PhysicalEntity67
stoichiometric coefficient: 1.0

UnificationXref1585
type: UnificationXref
id: 4181473
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181473

Stoichiometry2291
type: Stoichiometry
physical entity: Protein2624
stoichiometric coefficient: 1.0

UnificationXref1586
type: UnificationXref
id: 4181474
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181474

Stoichiometry2290
type: Stoichiometry
physical entity: Protein2594
stoichiometric coefficient: 1.0

UnificationXref1583
type: UnificationXref
id: 4181471
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181471

UnificationXref1584
type: UnificationXref
id: A0JPS9
db: UniProt

UnificationXref1589
type: UnificationXref
id: CHEBI:17984
db: ChEBI

UnificationXref1587
type: UnificationXref
id: 4181476
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181476

UnificationXref1588
type: UnificationXref
id: REACT_156083
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_156083.3

UnificationXref1581
type: UnificationXref
id: 4181469
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181469

UnificationXref1582
type: UnificationXref
id: Q9M8L4
db: UniProt

UnificationXref1580
type: UnificationXref
id: F4HS76
db: UniProt

Stoichiometry2299
type: Stoichiometry
physical entity: Protein6118
stoichiometric coefficient: 1.0

Stoichiometry2297
type: Stoichiometry
physical entity: PhysicalEntity61
stoichiometric coefficient: 1.0

Stoichiometry2298
type: Stoichiometry
physical entity: Protein2515
stoichiometric coefficient: 1.0

Stoichiometry2295
type: Stoichiometry
physical entity: PhysicalEntity68
stoichiometric coefficient: 1.0

Stoichiometry2296
type: Stoichiometry
physical entity: Protein2489
stoichiometric coefficient: 1.0

Stoichiometry2293
type: Stoichiometry
physical entity: PhysicalEntity360
stoichiometric coefficient: 1.0

Stoichiometry2294
type: Stoichiometry
physical entity: Protein2555
stoichiometric coefficient: 1.0

UnificationXref1594
type: UnificationXref
id: REACT_119202
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_119202.1

UnificationXref1595
type: UnificationXref
id: Q8GWG0
db: UniProt

http://identifiers.org/pubmed/8021246
type: PublicationXref
id: 8021246
author: Nicoll, DA
author: Bersohn, MM
author: Matsuoka, S
author: Burke, EP
author: Hryshko, LV
author: Lifton, RP
author: Li, Z
author: Philipson, KD
db: Pubmed
title: Cloning of the NCX2 isoform of the plasma membrane Na(+)-Ca2+ exchanger
source: J Biol Chem 269:17434-9
year: 1994

UnificationXref1596
type: UnificationXref
id: 4181431
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181431

http://identifiers.org/pubmed/22983114
type: PublicationXref
id: 22983114
author: Boutros, Michael
author: Bartscherer, Kerstin
author: Chaudhary, Varun
author: Gross, Julia Christina
db: Pubmed
title: Active Wnt proteins are secreted on exosomes
source: Nat. Cell Biol. 14:1036-45
year: 2012

UnificationXref1597
type: UnificationXref
id: 4193002
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4193002

UnificationXref1598
type: UnificationXref
id: REACT_114086
db: Reactome
id version: 8
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_114086.8

UnificationXref1599
type: UnificationXref
id: CHEBI:16337
db: ChEBI

UnificationXref1590
type: UnificationXref
id: 1500578
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1500578

UnificationXref1591
type: UnificationXref
id: REACT_118995
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_118995.1

UnificationXref1592
type: UnificationXref
id: CHEBI:16975
db: ChEBI

UnificationXref1593
type: UnificationXref
id: 1500604
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1500604

http://identifiers.org/pubmed/6693436
type: PublicationXref
id: 6693436
author: Hu, SZ
author: Wang, TS
author: Korn, D
db: Pubmed
title: DNA primase from KB cells. Characterization of a primase activity tightly associated with immunoaffinity-purified DNA polymerase-alpha.
source: J Biol Chem 259:1854-65
year: 1984

http://identifiers.org/pubmed/2408761
type: PublicationXref
id: 2408761
author: Sharp, PA
author: Moore, CL
db: Pubmed
title: Accurate cleavage and polyadenylation of exogenous RNA substrate.
source: Cell 41:845-55
year: 1985

Stoichiometry2096
type: Stoichiometry
physical entity: Complex759
stoichiometric coefficient: 1.0

Stoichiometry2095
type: Stoichiometry
physical entity: PhysicalEntity322
stoichiometric coefficient: 1.0

Stoichiometry2098
type: Stoichiometry
physical entity: Complex641
stoichiometric coefficient: 1.0

Stoichiometry2097
type: Stoichiometry
physical entity: SmallMolecule1014
stoichiometric coefficient: 1.0

Stoichiometry2099
type: Stoichiometry
physical entity: Protein2936
stoichiometric coefficient: 1.0

Stoichiometry2090
type: Stoichiometry
physical entity: Protein2936
stoichiometric coefficient: 1.0

Stoichiometry2091
type: Stoichiometry
physical entity: phospho-p-3S1089,S1107-UPF1
stoichiometric coefficient: 1.0

Stoichiometry2092
type: Stoichiometry
physical entity: Complex753
stoichiometric coefficient: 1.0

Stoichiometry2093
type: Stoichiometry
physical entity: Homologues of SMG6
stoichiometric coefficient: 1.0

Stoichiometry2094
type: Stoichiometry
physical entity: Protein2957
stoichiometric coefficient: 1.0

ChEBI:28477 7alpha,12alpha-dihydroxycholest-4-en-3-one
type: SmallMoleculeReference
name: 7alpha,12alpha-dihydroxycholest-4-en-3-one
xref: UnificationXref2324

Stoichiometry2089
type: Stoichiometry
physical entity: PhysicalEntity320
stoichiometric coefficient: 1.0

Stoichiometry2088
type: Stoichiometry
physical entity: Homologues of SMG7
stoichiometric coefficient: 1.0

Stoichiometry2087
type: Stoichiometry
physical entity: PhysicalEntity321
stoichiometric coefficient: 1.0

Stoichiometry2086
type: Stoichiometry
physical entity: Complex751
stoichiometric coefficient: 1.0

Stoichiometry2085
type: Stoichiometry
physical entity: Homologues of UPF3A
stoichiometric coefficient: 1.0

Stoichiometry2084
type: Stoichiometry
physical entity: Complex759
stoichiometric coefficient: 1.0

Stoichiometry2082
type: Stoichiometry
physical entity: Protein1255
stoichiometric coefficient: 1.0

Stoichiometry2083
type: Stoichiometry
physical entity: Homologues of PPP2R2A(2-447)
stoichiometric coefficient: 1.0

MPS IIID - Sanfilippo syndrome D
type: Pathway
data source: Provenance1
pathway component: REACT 129397.5
evidence: Evidence1844
xref: UnificationXref19676
xref: UnificationXref19675
pathway order: PathwayStep78
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Stoichiometry2080
type: Stoichiometry
physical entity: Homologues of SMG6
stoichiometric coefficient: 1.0

Stoichiometry2081
type: Stoichiometry
physical entity: Protein1263
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/3893466
type: PublicationXref
id: 3893466
author: Jornvall, H
db: Pubmed
title: Alcohol dehydrogenases, aldehyde dehydrogenases, and related enzymes
source: Alcohol 2:61-6
year: 1985

http://identifiers.org/pubmed/7890667
type: PublicationXref
id: 7890667
author: Liu, SM
author: Cheng, HF
author: Wong, LP
author: King, K
author: Jiang, MJ
author: Chen, CL
author: Lomasney, JW
db: Pubmed
title: Cloning and identification of amino acid residues of human phospholipase C delta 1 essential for catalysis
source: J Biol Chem 270:5495-505
year: 1995

Stoichiometry2078
type: Stoichiometry
physical entity: PhysicalEntity320
stoichiometric coefficient: 1.0

Stoichiometry2077
type: Stoichiometry
physical entity: Homologues of SMG7
stoichiometric coefficient: 1.0

Stoichiometry2079
type: Stoichiometry
physical entity: phospho-p-3S1089,S1107-UPF1
stoichiometric coefficient: 1.0

Stoichiometry2074
type: Stoichiometry
physical entity: Complex750
stoichiometric coefficient: 1.0

Stoichiometry2073
type: Stoichiometry
physical entity: SmallMolecule14
stoichiometric coefficient: 4.0

Stoichiometry2076
type: Stoichiometry
physical entity: Complex751
stoichiometric coefficient: 1.0

UniProt:F4JLJ2
type: ProteinReference
xref: UnificationXref3865
organism: Arabidopsis thaliana

Stoichiometry2075
type: Stoichiometry
physical entity: phospho-p-3S1089,S1107-UPF1
stoichiometric coefficient: 1.0

UniProt:F4JLJ3
type: ProteinReference
xref: UnificationXref15294
organism: Arabidopsis thaliana

Stoichiometry2070
type: Stoichiometry
physical entity: Protein4865
stoichiometric coefficient: 1.0

Diphosphatidylglycerol
type: SmallMoleculeReference
name: cardiolipin
name: cardiolipin [ChEBI:28494]
name: cardiolipins
name: 1',3'-Bis(1,2-diacyl-sn-glycero-3-phospho)-sn-glycerol
xref: UnificationXref2919

Stoichiometry2071
type: Stoichiometry
physical entity: Complex751
stoichiometric coefficient: 1.0

Stoichiometry2072
type: Stoichiometry
physical entity: SmallMolecule11
stoichiometric coefficient: 4.0

http://identifiers.org/pubmed/8662720
type: PublicationXref
id: 8662720
author: Korenberg, J
author: Garrow, TA
author: Qi, H
author: Choi, YJ
author: Shane, B
author: Chen, L
db: Pubmed
title: Purification and properties of human cytosolic folylpoly-gamma-glutamate synthetase and organization, localization, and differential splicing of its gene
source: J Biol Chem 271:13077-87
year: 1996

http://identifiers.org/pubmed/15585605
type: PublicationXref
id: 15585605
author: Takeda, K
author: Akira, S
db: Pubmed
title: TIRAP/Mal, TRIF and TRAM. Differential utilization of these TIR
source: Int Immunol 17:1-14
year: 2005

http://identifiers.org/pubmed/8618861
type: PublicationXref
id: 8618861
author: Nevins, JR
author: DeGregori, J
author: Ohtani, K
db: Pubmed
title: Regulation of the cyclin E gene by transcription factor E2F1
source: Proc Natl Acad Sci U S A 92:12146-50
year: 1995

PPARA Activates Gene Expression
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction121
pathway component: BiochemicalReaction120
pathway component: TemplateReaction2
pathway component: TemplateReaction1
pathway component: TemplateReaction4
pathway component: TemplateReaction3
pathway component: TemplateReaction5
evidence: Evidence168
xref: UnificationXref1896
xref: UnificationXref1897
pathway order: PathwayStep166
pathway order: PathwayStep164
pathway order: PathwayStep162
pathway order: PathwayStep167
pathway order: PathwayStep165
pathway order: PathwayStep161
pathway order: PathwayStep163
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/9461603
type: PublicationXref
id: 9461603
author: Aguado, B
author: Campbell, RD
db: Pubmed
title: Characterization of a human lysophosphatidic acid acyltransferase that is encoded by a gene located in the class III region of the human major histocompatibility complex
source: J Biol Chem 273:4096-105
year: 1998

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP9(60-707)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: proMMP9 intermediate form
xref: UnificationXref15723
feature: FragmentFeature4854
cellular location: GO:0005576
comment: Reactome DB_ID: 4196198
display name: Q84W77

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP9(60-707)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: proMMP9 intermediate form
xref: UnificationXref15724
feature: FragmentFeature4855
cellular location: GO:0005576
comment: Reactome DB_ID: 4196199
display name: Q0WVU1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP9(60-707)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: proMMP9 intermediate form
xref: UnificationXref15725
feature: FragmentFeature4856
cellular location: GO:0005576
comment: Reactome DB_ID: 4196200
display name: O04529

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP9(60-707)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: proMMP9 intermediate form
xref: UnificationXref15726
feature: FragmentFeature4857
cellular location: GO:0005576
comment: Reactome DB_ID: 4196201
display name: O48680

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O23507
data source: Provenance1
name: MMP9(60-707)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: proMMP9 intermediate form
xref: UnificationXref15719
feature: FragmentFeature4850
cellular location: GO:0005576
comment: Reactome DB_ID: 4196194
display name: O23507

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP9(60-707)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: proMMP9 intermediate form
xref: UnificationXref15720
feature: FragmentFeature4851
cellular location: GO:0005576
comment: Reactome DB_ID: 4196195
display name: O65340

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: MMP9(60-707)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: proMMP9 intermediate form
xref: UnificationXref15721
feature: FragmentFeature4852
cellular location: GO:0005576
comment: Reactome DB_ID: 4196196
display name: Q8LET7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP9(60-707)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: proMMP9 intermediate form
xref: UnificationXref15722
feature: FragmentFeature4853
cellular location: GO:0005576
comment: Reactome DB_ID: 4196197
display name: Q5XF51

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP9(60-707)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: proMMP9 intermediate form
xref: UnificationXref15718
feature: FragmentFeature4849
cellular location: GO:0005576
comment: Reactome DB_ID: 4196193
display name: Q9ZUJ5

Homologues of MMP9(60-707)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15728
cellular location: GO:0005576
comment: Reactome DB_ID: 4196203
comment: Converted from EntitySet in Reactome

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP9 fragment 20-59
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: MMP9(20-59)
xref: UnificationXref15716
feature: FragmentFeature4848
cellular location: GO:0005576
comment: Reactome DB_ID: 4196213
display name: Q8GWW6

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: Type V collagenase
name: 92 kDa gelatinase
name: Matrix metalloproteinase-9 (MMP9)
name: O04529
name: MMP9_HUMAN
xref: UnificationXref15739
feature: FragmentFeature4866
cellular location: GO:0005576
comment: Reactome DB_ID: 4196364
display name: MMP9

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: Type V collagenase
name: 92 kDa gelatinase
name: Matrix metalloproteinase-9 (MMP9)
name: O48680
name: MMP9_HUMAN
xref: UnificationXref15740
feature: FragmentFeature4867
cellular location: GO:0005576
comment: Reactome DB_ID: 4196365
display name: MMP9

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Type V collagenase
name: 92 kDa gelatinase
name: Matrix metalloproteinase-9 (MMP9)
name: Q84W77
name: MMP9_HUMAN
xref: UnificationXref15737
feature: FragmentFeature4864
cellular location: GO:0005576
comment: Reactome DB_ID: 4196362
display name: MMP9

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Q0WVU1
name: Type V collagenase
name: 92 kDa gelatinase
name: Matrix metalloproteinase-9 (MMP9)
name: MMP9_HUMAN
xref: UnificationXref15738
feature: FragmentFeature4865
cellular location: GO:0005576
comment: Reactome DB_ID: 4196363
display name: MMP9

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Type V collagenase
name: 92 kDa gelatinase
name: Matrix metalloproteinase-9 (MMP9)
name: MMP9_HUMAN
xref: UnificationXref15735
feature: FragmentFeature4862
cellular location: GO:0005576
comment: Reactome DB_ID: 4196360
display name: MMP9

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Type V collagenase
name: 92 kDa gelatinase
name: Matrix metalloproteinase-9 (MMP9)
name: Q5XF51
name: MMP9_HUMAN
xref: UnificationXref15736
feature: FragmentFeature4863
cellular location: GO:0005576
comment: Reactome DB_ID: 4196361
display name: MMP9

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Type V collagenase
name: 92 kDa gelatinase
name: Matrix metalloproteinase-9 (MMP9)
name: MMP9_HUMAN
xref: UnificationXref15733
feature: FragmentFeature4860
cellular location: GO:0005576
comment: Reactome DB_ID: 4196358
display name: MMP9

http://identifiers.org/pubmed/8104944
type: PublicationXref
id: 8104944
author: Brown, WC
author: Campbell, JL
db: Pubmed
title: Interaction of proliferating cell nuclear antigen with yeast DNA polymerase delta.
source: J Biol Chem 268:21706-10
year: 1993

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: Type V collagenase
name: 92 kDa gelatinase
name: Matrix metalloproteinase-9 (MMP9)
name: O65340
name: MMP9_HUMAN
xref: UnificationXref15734
feature: FragmentFeature4861
cellular location: GO:0005576
comment: Reactome DB_ID: 4196359
display name: MMP9

Homologues of MMP9
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q8LET7
member physical entity: O23507
xref: UnificationXref15742
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196367

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Q9ZUJ5
name: Type V collagenase
name: 92 kDa gelatinase
name: Matrix metalloproteinase-9 (MMP9)
name: MMP9_HUMAN
xref: UnificationXref15732
feature: FragmentFeature4859
cellular location: GO:0005576
comment: Reactome DB_ID: 4196357
display name: MMP9

http://identifiers.org/pubmed/18043707
type: PublicationXref
id: 18043707
author: Hamm, HE
author: Oldham, WM
db: Pubmed
title: Heterotrimeric G protein activation by G-protein-coupled receptors
source: Nat Rev Mol Cell Biol 9:60-71
year: 2008

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP9(60-707)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: proMMP9 intermediate form
xref: UnificationXref15727
feature: FragmentFeature4858
cellular location: GO:0005576
comment: Reactome DB_ID: 4196202
display name: Q8GWW6

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O23507
data source: Provenance1
name: MMP9 fragment 60-106
name: MMP9(60-106)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15744
feature: FragmentFeature4870
cellular location: GO:0005576
comment: Reactome DB_ID: 4196369
display name: O23507

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP9 fragment 60-106
name: MMP9(60-106)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15745
feature: FragmentFeature4871
cellular location: GO:0005576
comment: Reactome DB_ID: 4196370
display name: O65340

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: MMP9 fragment 60-106
name: MMP9(60-106)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15746
feature: FragmentFeature4872
cellular location: GO:0005576
comment: Reactome DB_ID: 4196371
display name: Q8LET7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP9 fragment 60-106
name: MMP9(60-106)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15747
feature: FragmentFeature4873
cellular location: GO:0005576
comment: Reactome DB_ID: 4196372
display name: Q5XF51

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP9 fragment 60-106
name: MMP9(60-106)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15748
feature: FragmentFeature4874
cellular location: GO:0005576
comment: Reactome DB_ID: 4196373
display name: Q84W77

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP9 fragment 60-106
name: MMP9(60-106)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15749
feature: FragmentFeature4875
cellular location: GO:0005576
comment: Reactome DB_ID: 4196374
display name: Q0WVU1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP9 fragment 60-106
name: MMP9(60-106)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15750
feature: FragmentFeature4876
cellular location: GO:0005576
comment: Reactome DB_ID: 4196375
display name: O04529

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Q8GWW6
name: Type V collagenase
name: 92 kDa gelatinase
name: Matrix metalloproteinase-9 (MMP9)
name: MMP9_HUMAN
xref: UnificationXref15741
feature: FragmentFeature4868
cellular location: GO:0005576
comment: Reactome DB_ID: 4196366
display name: MMP9

Homologues of MMP9(60-106)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15753
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196378

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP9 fragment 60-106
name: MMP9(60-106)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15743
feature: FragmentFeature4869
cellular location: GO:0005576
comment: Reactome DB_ID: 4196368
display name: Q9ZUJ5

http://identifiers.org/pubmed/16271386
type: PublicationXref
id: 16271386
author: Tomari, Y
author: Bartel, DP
author: Zamore, Phillip D
author: Shin, C
author: Matranga, C
db: Pubmed
title: Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
source: Cell 123:607-20
year: 2005

SequenceSite2896
type: SequenceSite
position status: EQUAL
sequence position: 587

SequenceSite2897
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite2894
type: SequenceSite
position status: EQUAL
sequence position: 587

SequenceSite2895
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite2898
type: SequenceSite
position status: EQUAL
sequence position: 587

SequenceSite2899
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite2893
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite2892
type: SequenceSite
position status: EQUAL
sequence position: 587

SequenceSite2891
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite2890
type: SequenceSite
position status: EQUAL
sequence position: 587

http://identifiers.org/pubmed/21944752
type: PublicationXref
id: 21944752
author: Pierrel, F
author: Lill, R
author: Webert, H
author: Mühlenhoff, U
author: Fontecave, M
author: Ozeir, M
db: Pubmed
title: Coenzyme Q biosynthesis: Coq6 is required for the C5-hydroxylation reaction and substrate analogs rescue Coq6 deficiency
source: Chem Biol 18:1134-42
year: 2011

SequenceSite2888
type: SequenceSite
position status: EQUAL
sequence position: 587

SequenceSite2887
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite2889
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite2884
type: SequenceSite
position status: EQUAL
sequence position: 315

SequenceSite2883
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2886
type: SequenceSite
position status: EQUAL
sequence position: 587

SequenceSite2885
type: SequenceSite
position status: EQUAL
sequence position: 43

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP7 intermediate form
name: Q0WVU1
name: MMP7_HUMAN
name: MMP7(51-267)
name: Matrilysin-1
xref: UnificationXref15669
feature: FragmentFeature4815
cellular location: GO:0005576
comment: Reactome DB_ID: 4196386
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP7 intermediate form
name: Q84W77
name: MMP7_HUMAN
name: MMP7(51-267)
name: Matrilysin-1
xref: UnificationXref15668
feature: FragmentFeature4814
cellular location: GO:0005576
comment: Reactome DB_ID: 4196385
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP7 intermediate form
name: MMP7_HUMAN
name: MMP7(51-267)
name: O48680
name: Matrilysin-1
xref: UnificationXref15671
feature: FragmentFeature4817
cellular location: GO:0005576
comment: Reactome DB_ID: 4196388
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP7 intermediate form
name: O04529
name: MMP7_HUMAN
name: MMP7(51-267)
name: Matrilysin-1
xref: UnificationXref15670
feature: FragmentFeature4816
cellular location: GO:0005576
comment: Reactome DB_ID: 4196387
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP7 intermediate form
name: Q5XF51
name: MMP7_HUMAN
name: MMP7(51-267)
name: Matrilysin-1
xref: UnificationXref15667
feature: FragmentFeature4813
cellular location: GO:0005576
comment: Reactome DB_ID: 4196384
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP7 intermediate form
name: O65340
name: MMP7_HUMAN
name: MMP7(51-267)
name: Matrilysin-1
xref: UnificationXref15665
feature: FragmentFeature4811
cellular location: GO:0005576
comment: Reactome DB_ID: 4196382
display name: MMP7

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP7 intermediate form
name: MMP7_HUMAN
name: MMP7(51-267)
name: Matrilysin-1
xref: UnificationXref15666
feature: FragmentFeature4812
cellular location: GO:0005576
comment: Reactome DB_ID: 4196383
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Q8GWW6
name: MMP7(18-94)
name: MMP7 fragment 18-94
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15659
feature: FragmentFeature4808
cellular location: GO:0005576
comment: Reactome DB_ID: 4196123
display name: MMP7

Homologues of MMP7(51-267)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q8LET7
member physical entity: O23507
xref: UnificationXref15673
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196390

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP7 intermediate form
name: Q9ZUJ5
name: MMP7_HUMAN
name: MMP7(51-267)
name: Matrilysin-1
xref: UnificationXref15663
feature: FragmentFeature4809
cellular location: GO:0005576
comment: Reactome DB_ID: 4196380
display name: MMP7

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP7 intermediate form
name: MMP7_HUMAN
name: MMP7(51-267)
name: Matrilysin-1
xref: UnificationXref15664
feature: FragmentFeature4810
cellular location: GO:0005576
comment: Reactome DB_ID: 4196381
display name: MMP7

SequenceSite2880
type: SequenceSite
position status: EQUAL
sequence position: 315

SequenceSite2881
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2882
type: SequenceSite
position status: EQUAL
sequence position: 315

SequenceSite2879
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17599
type: UnificationXref
id: 4183807
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183807

SequenceSite2878
type: SequenceSite
position status: EQUAL
sequence position: 315

UnificationXref17598
type: UnificationXref
id: 4183806
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183806

SequenceSite2877
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17597
type: UnificationXref
id: 4183881
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183881

SequenceSite2876
type: SequenceSite
position status: EQUAL
sequence position: 587

UnificationXref17596
type: UnificationXref
id: 4183844
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183844

SequenceSite2875
type: SequenceSite
position status: EQUAL
sequence position: 43

UnificationXref17595
type: UnificationXref
id: 4183843
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183843

SequenceSite2874
type: SequenceSite
position status: EQUAL
sequence position: 587

UnificationXref17594
type: UnificationXref
id: 4183842
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183842

SequenceSite2873
type: SequenceSite
position status: EQUAL
sequence position: 43

UnificationXref17593
type: UnificationXref
id: 4183799
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183799

SequenceSite2872
type: SequenceSite
position status: EQUAL
sequence position: 587

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP7 fragment 51-94
name: MMP7(51-94)
name: MMP7_HUMAN
name: O48680
name: Matrilysin-1
xref: UnificationXref15682
feature: FragmentFeature4827
cellular location: GO:0005576
comment: Reactome DB_ID: 4196530
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP7 fragment 51-94
name: O04529
name: MMP7(51-94)
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15681
feature: FragmentFeature4826
cellular location: GO:0005576
comment: Reactome DB_ID: 4196529
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP7 fragment 51-94
name: Q0WVU1
name: MMP7(51-94)
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15680
feature: FragmentFeature4825
cellular location: GO:0005576
comment: Reactome DB_ID: 4196528
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP7 fragment 51-94
name: MMP7(51-94)
name: Q84W77
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15679
feature: FragmentFeature4824
cellular location: GO:0005576
comment: Reactome DB_ID: 4196527
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP7 fragment 51-94
name: MMP7(51-94)
name: Q5XF51
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15678
feature: FragmentFeature4823
cellular location: GO:0005576
comment: Reactome DB_ID: 4196526
display name: MMP7

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP7 fragment 51-94
name: MMP7(51-94)
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15677
feature: FragmentFeature4822
cellular location: GO:0005576
comment: Reactome DB_ID: 4196525
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP7 fragment 51-94
name: MMP7(51-94)
name: O65340
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15676
feature: FragmentFeature4821
cellular location: GO:0005576
comment: Reactome DB_ID: 4196524
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Q9ZUJ5
name: MMP7 fragment 51-94
name: MMP7(51-94)
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15674
feature: FragmentFeature4819
cellular location: GO:0005576
comment: Reactome DB_ID: 4196522
display name: MMP7

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP7 fragment 51-94
name: MMP7(51-94)
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15675
feature: FragmentFeature4820
cellular location: GO:0005576
comment: Reactome DB_ID: 4196523
display name: MMP7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP7 intermediate form
name: Q8GWW6
name: MMP7_HUMAN
name: MMP7(51-267)
name: Matrilysin-1
xref: UnificationXref15672
feature: FragmentFeature4818
cellular location: GO:0005576
comment: Reactome DB_ID: 4196389
display name: MMP7

Homologues of MMP7(51-94)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: O23507
member physical entity: Q8LET7
xref: UnificationXref15684
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196532

UnificationXref17591
type: UnificationXref
id: 4183810
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183810

SequenceSite2870
type: SequenceSite
position status: EQUAL
sequence position: 587

UnificationXref17592
type: UnificationXref
id: 4183811
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183811

SequenceSite2871
type: SequenceSite
position status: EQUAL
sequence position: 43

UnificationXref17590
type: UnificationXref
id: 4183809
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183809

SequenceSite2862
type: SequenceSite
position status: EQUAL
sequence position: 587

SequenceSite2861
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite2864
type: SequenceSite
position status: EQUAL
sequence position: 587

SequenceSite2863
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite2866
type: SequenceSite
position status: EQUAL
sequence position: 587

SequenceSite2865
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite2868
type: SequenceSite
position status: EQUAL
sequence position: 587

SequenceSite2867
type: SequenceSite
position status: EQUAL
sequence position: 43

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP9(20-707)
name: proMMP9
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15698
feature: FragmentFeature4831
cellular location: GO:0005576
comment: Reactome DB_ID: 4196184
display name: O65340

SequenceSite2869
type: SequenceSite
position status: EQUAL
sequence position: 43

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP9(20-707)
name: proMMP9
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15700
feature: FragmentFeature4833
cellular location: GO:0005576
comment: Reactome DB_ID: 4196186
display name: Q5XF51

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: MMP9(20-707)
name: proMMP9
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15699
feature: FragmentFeature4832
cellular location: GO:0005576
comment: Reactome DB_ID: 4196185
display name: Q8LET7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP9(20-707)
name: proMMP9
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15702
feature: FragmentFeature4835
cellular location: GO:0005576
comment: Reactome DB_ID: 4196188
display name: Q0WVU1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP9(20-707)
name: proMMP9
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15701
feature: FragmentFeature4834
cellular location: GO:0005576
comment: Reactome DB_ID: 4196187
display name: Q84W77

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP9(20-707)
name: proMMP9
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15704
feature: FragmentFeature4837
cellular location: GO:0005576
comment: Reactome DB_ID: 4196190
display name: O48680

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP9(20-707)
name: proMMP9
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15703
feature: FragmentFeature4836
cellular location: GO:0005576
comment: Reactome DB_ID: 4196189
display name: O04529

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Q8GWW6
name: MMP7 fragment 51-94
name: MMP7(51-94)
name: MMP7_HUMAN
name: Matrilysin-1
xref: UnificationXref15683
feature: FragmentFeature4828
cellular location: GO:0005576
comment: Reactome DB_ID: 4196531
display name: MMP7

Homologues of MMP9(20-707)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15706
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196192

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP9(20-707)
name: proMMP9
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15696
feature: FragmentFeature4829
cellular location: GO:0005576
comment: Reactome DB_ID: 4196182
display name: Q9ZUJ5

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O23507
data source: Provenance1
name: MMP9(20-707)
name: proMMP9
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15697
feature: FragmentFeature4830
cellular location: GO:0005576
comment: Reactome DB_ID: 4196183
display name: O23507

SequenceSite2860
type: SequenceSite
position status: EQUAL
sequence position: 587

SequenceSite2853
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite2852
type: SequenceSite
position status: EQUAL
sequence position: 538

SequenceSite2851
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2850
type: SequenceSite
position status: EQUAL
sequence position: 538

SequenceSite2857
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite2856
type: SequenceSite
position status: EQUAL
sequence position: 587

SequenceSite2855
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite2854
type: SequenceSite
position status: EQUAL
sequence position: 587

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP9 fragment 20-59
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: MMP9(20-59)
xref: UnificationXref15711
feature: FragmentFeature4843
cellular location: GO:0005576
comment: Reactome DB_ID: 4196208
display name: Q5XF51

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: MMP9 fragment 20-59
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: MMP9(20-59)
xref: UnificationXref15710
feature: FragmentFeature4842
cellular location: GO:0005576
comment: Reactome DB_ID: 4196207
display name: Q8LET7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP9 fragment 20-59
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: MMP9(20-59)
xref: UnificationXref15709
feature: FragmentFeature4841
cellular location: GO:0005576
comment: Reactome DB_ID: 4196206
display name: O65340

SequenceSite2859
type: SequenceSite
position status: EQUAL
sequence position: 43

Metabolism of nitric oxide
type: Pathway
data source: Provenance1
pathway component: REACT 126384.5
evidence: Evidence418
xref: RelationshipXref487
xref: UnificationXref4194
xref: UnificationXref4193
pathway order: PathwayStep415
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O23507
data source: Provenance1
name: MMP9 fragment 20-59
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: MMP9(20-59)
xref: UnificationXref15708
feature: FragmentFeature4840
cellular location: GO:0005576
comment: Reactome DB_ID: 4196205
display name: O23507

SequenceSite2858
type: SequenceSite
position status: EQUAL
sequence position: 587

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP9 fragment 20-59
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: MMP9(20-59)
xref: UnificationXref15715
feature: FragmentFeature4847
cellular location: GO:0005576
comment: Reactome DB_ID: 4196212
display name: O48680

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP9 fragment 20-59
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: MMP9(20-59)
xref: UnificationXref15714
feature: FragmentFeature4846
cellular location: GO:0005576
comment: Reactome DB_ID: 4196211
display name: O04529

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP9 fragment 20-59
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: MMP9(20-59)
xref: UnificationXref15713
feature: FragmentFeature4845
cellular location: GO:0005576
comment: Reactome DB_ID: 4196210
display name: Q0WVU1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP9 fragment 20-59
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: MMP9(20-59)
xref: UnificationXref15712
feature: FragmentFeature4844
cellular location: GO:0005576
comment: Reactome DB_ID: 4196209
display name: Q84W77

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP9 fragment 20-59
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
name: MMP9(20-59)
xref: UnificationXref15707
feature: FragmentFeature4839
cellular location: GO:0005576
comment: Reactome DB_ID: 4196204
display name: Q9ZUJ5

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP9(20-707)
name: proMMP9
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15705
feature: FragmentFeature4838
cellular location: GO:0005576
comment: Reactome DB_ID: 4196191
display name: Q8GWW6

Homologues of MMP9(20-59)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15717
cellular location: GO:0005576
comment: Reactome DB_ID: 4196214
comment: Converted from EntitySet in Reactome

Homologues of MMP13(77-471)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: O23507
member physical entity: Q8LET7
xref: UnificationXref15777
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196447

UnificationXref1657
type: UnificationXref
id: Q93XM7
db: UniProt

MMP13(20-471)
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q8GWW6
name: proMMP13
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15765
feature: FragmentFeature4888
cellular location: GO:0005576
comment: Reactome DB_ID: 4196308
display name: MMP13

UnificationXref1658
type: UnificationXref
id: 4186627
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186627

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13 intermediate form 77-471
name: Collagenase 3
name: MMP13_HUMAN
name: MMP13(77-471)
xref: UnificationXref15768
feature: FragmentFeature4890
cellular location: GO:0005576
comment: Reactome DB_ID: 4196438
display name: MMP13

UnificationXref1659
type: UnificationXref
id: 4186629
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186629

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Q9ZUJ5
name: MMP13 intermediate form 77-471
name: Collagenase 3
name: MMP13_HUMAN
name: MMP13(77-471)
xref: UnificationXref15767
feature: FragmentFeature4889
cellular location: GO:0005576
comment: Reactome DB_ID: 4196437
display name: MMP13

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13 intermediate form 77-471
name: Collagenase 3
name: MMP13_HUMAN
name: MMP13(77-471)
xref: UnificationXref15770
feature: FragmentFeature4892
cellular location: GO:0005576
comment: Reactome DB_ID: 4196440
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP13 intermediate form 77-471
name: Collagenase 3
name: O65340
name: MMP13_HUMAN
name: MMP13(77-471)
xref: UnificationXref15769
feature: FragmentFeature4891
cellular location: GO:0005576
comment: Reactome DB_ID: 4196439
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP13 intermediate form 77-471
name: Collagenase 3
name: Q84W77
name: MMP13_HUMAN
name: MMP13(77-471)
xref: UnificationXref15772
feature: FragmentFeature4894
cellular location: GO:0005576
comment: Reactome DB_ID: 4196442
display name: MMP13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP13 intermediate form 77-471
name: Collagenase 3
name: Q5XF51
name: MMP13_HUMAN
name: MMP13(77-471)
xref: UnificationXref15771
feature: FragmentFeature4893
cellular location: GO:0005576
comment: Reactome DB_ID: 4196441
display name: MMP13

UnificationXref17557
type: UnificationXref
id: 4183878
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183878

SequenceSite2957
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref1661
type: UnificationXref
id: 4181395
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181395

UnificationXref17558
type: UnificationXref
id: 4183879
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183879

SequenceSite2958
type: SequenceSite
position status: EQUAL
sequence position: 496

UnificationXref1660
type: UnificationXref
id: REACT_159068
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_159068.3

UnificationXref17559
type: UnificationXref
id: 4183820
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183820

SequenceSite2959
type: SequenceSite
position status: EQUAL
sequence position: 314

UnificationXref1663
type: UnificationXref
id: REACT_34284
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_34284.10

UnificationXref1662
type: UnificationXref
id: 4181397
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181397

UnificationXref1665
type: UnificationXref
id: 4183147
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183147

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP13 intermediate form 77-471
name: Q0WVU1
name: Collagenase 3
name: MMP13_HUMAN
name: MMP13(77-471)
xref: UnificationXref15773
feature: FragmentFeature4895
cellular location: GO:0005576
comment: Reactome DB_ID: 4196443
display name: MMP13

UnificationXref1664
type: UnificationXref
id: 4183146
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183146

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP13 intermediate form 77-471
name: O04529
name: Collagenase 3
name: MMP13_HUMAN
name: MMP13(77-471)
xref: UnificationXref15774
feature: FragmentFeature4896
cellular location: GO:0005576
comment: Reactome DB_ID: 4196444
display name: MMP13

UnificationXref1667
type: UnificationXref
id: 4183149
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183149

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP13 intermediate form 77-471
name: Collagenase 3
name: MMP13_HUMAN
name: O48680
name: MMP13(77-471)
xref: UnificationXref15775
feature: FragmentFeature4897
cellular location: GO:0005576
comment: Reactome DB_ID: 4196445
display name: MMP13

UnificationXref1666
type: UnificationXref
id: 4183148
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183148

UnificationXref17550
type: UnificationXref
id: 4183830
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183830

SequenceSite2950
type: SequenceSite
position status: EQUAL
sequence position: 736

UnificationXref17551
type: UnificationXref
id: 4183893
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183893

SequenceSite2951
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17552
type: UnificationXref
id: 4183841
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183841

SequenceSite2952
type: SequenceSite
position status: EQUAL
sequence position: 888

UnificationXref17553
type: UnificationXref
id: 4183887
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183887

SequenceSite2953
type: SequenceSite
position status: EQUAL
sequence position: 314

UnificationXref17554
type: UnificationXref
id: 4183888
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183888

SequenceSite2954
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17555
type: UnificationXref
id: 4183889
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183889

SequenceSite2955
type: SequenceSite
position status: EQUAL
sequence position: 496

UnificationXref17556
type: UnificationXref
id: 4183877
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183877

SequenceSite2956
type: SequenceSite
position status: EQUAL
sequence position: 314

MMP13(20-471)
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q0WVU1
name: proMMP13
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15762
feature: FragmentFeature4885
cellular location: GO:0005576
comment: Reactome DB_ID: 4196305
display name: MMP13

MMP13(20-471)
type: Protein
entity reference: O23507
data source: Provenance1
name: O23507
name: Note: the coordinates are copied over from Homo sapiens.
name: proMMP13
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15757
feature: FragmentFeature4880
cellular location: GO:0005576
comment: Reactome DB_ID: 4196300
display name: MMP13

MMP13(20-471)
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q9ZUJ5
name: proMMP13
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15756
feature: FragmentFeature4879
cellular location: GO:0005576
comment: Reactome DB_ID: 4196299
display name: MMP13

Homologues of MMP13(20-471)
type: Protein
data source: Provenance1
member physical entity: MMP13(20-471)
xref: UnificationXref15766
cellular location: GO:0005576
comment: Reactome DB_ID: 4196309
comment: Converted from EntitySet in Reactome

UnificationXref1668
type: UnificationXref
id: 4183150
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183150

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: MMP9 fragment 60-106
name: MMP9(60-106)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15752
feature: FragmentFeature4878
cellular location: GO:0005576
comment: Reactome DB_ID: 4196377
display name: Q8GWW6

UnificationXref1669
type: UnificationXref
id: 4183151
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183151

MMP13(20-471)
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: proMMP13
name: Collagenase 3
name: Q84W77
name: MMP13_HUMAN
xref: UnificationXref15761
feature: FragmentFeature4884
cellular location: GO:0005576
comment: Reactome DB_ID: 4196304
display name: MMP13

MMP13(20-471)
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: proMMP13
name: Collagenase 3
name: Q5XF51
name: MMP13_HUMAN
xref: UnificationXref15760
feature: FragmentFeature4883
cellular location: GO:0005576
comment: Reactome DB_ID: 4196303
display name: MMP13

MMP13(20-471)
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Q8LET7
name: Note: the coordinates are copied over from Homo sapiens.
name: proMMP13
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15759
feature: FragmentFeature4882
cellular location: GO:0005576
comment: Reactome DB_ID: 4196302
display name: MMP13

MMP13(20-471)
type: Protein
entity reference: O65340
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: proMMP13
name: Collagenase 3
name: O65340
name: MMP13_HUMAN
xref: UnificationXref15758
feature: FragmentFeature4881
cellular location: GO:0005576
comment: Reactome DB_ID: 4196301
display name: MMP13

UnificationXref1674
type: UnificationXref
id: 4183156
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183156

UnificationXref1673
type: UnificationXref
id: 4183155
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183155

UnificationXref17568
type: UnificationXref
id: 4183855
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183855

SequenceSite2968
type: SequenceSite
position status: EQUAL
sequence position: 314

UnificationXref1672
type: UnificationXref
id: 4183154
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183154

UnificationXref17569
type: UnificationXref
id: 4183856
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183856

SequenceSite2969
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref1671
type: UnificationXref
id: 4183153
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183153

MMP13(20-471)
type: Protein
entity reference: O04529
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: proMMP13
name: O04529
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15763
feature: FragmentFeature4886
cellular location: GO:0005576
comment: Reactome DB_ID: 4196306
display name: MMP13

UnificationXref1678
type: UnificationXref
id: 4186605
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186605

MMP13(20-471)
type: Protein
entity reference: O48680
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: proMMP13
name: Collagenase 3
name: MMP13_HUMAN
name: O48680
xref: UnificationXref15764
feature: FragmentFeature4887
cellular location: GO:0005576
comment: Reactome DB_ID: 4196307
display name: MMP13

UnificationXref1677
type: UnificationXref
id: 4186603
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186603

UnificationXref1676
type: UnificationXref
id: 4186601
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186601

UnificationXref1675
type: UnificationXref
id: MOD:00046
db: MOD

UnificationXref17562
type: UnificationXref
id: 4183817
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183817

SequenceSite2962
type: SequenceSite
position status: EQUAL
sequence position: 314

http://identifiers.org/pubmed/19359157
type: PublicationXref
id: 19359157
author: Lykke-Andersen, J
author: Rebbapragada, I
db: Pubmed
title: Execution of nonsense-mediated mRNA decay: what defines a substrate?
source: Curr Opin Cell Biol 21:394-402
year: 2009

UnificationXref17563
type: UnificationXref
id: 4183818
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183818

SequenceSite2963
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17560
type: UnificationXref
id: 4183882
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183882

SequenceSite2960
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17561
type: UnificationXref
id: 4183792
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183792

SequenceSite2961
type: SequenceSite
position status: EQUAL
sequence position: 496

UnificationXref17566
type: UnificationXref
id: 4183816
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183816

SequenceSite2966
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref1670
type: UnificationXref
id: 4183152
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183152

UnificationXref17567
type: UnificationXref
id: 4183854
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183854

SequenceSite2967
type: SequenceSite
position status: EQUAL
sequence position: 496

UnificationXref17564
type: UnificationXref
id: 4183819
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183819

SequenceSite2964
type: SequenceSite
position status: EQUAL
sequence position: 496

UnificationXref17565
type: UnificationXref
id: 4183894
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183894

SequenceSite2965
type: SequenceSite
position status: EQUAL
sequence position: 314

UnificationXref17570
type: UnificationXref
id: 4183835
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183835

Q8LET7
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13(20-54)
name: MMP13 fragment 20-54
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15794
feature: FragmentFeature4912
cellular location: GO:0005576
comment: Reactome DB_ID: 4196499
display name: MMP13

UnificationXref1639
type: UnificationXref
id: Q9SLD2
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O65340
data source: Provenance1
name: MMP13(20-54)
name: MMP13 fragment 20-54
name: Collagenase 3
name: O65340
name: MMP13_HUMAN
xref: UnificationXref15793
feature: FragmentFeature4911
cellular location: GO:0005576
comment: Reactome DB_ID: 4196498
display name: MMP13

Homologues of MMP13(20-54)
type: Protein
data source: Provenance1
member physical entity: O23507
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q8LET7
xref: UnificationXref15801
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196506

UnificationXref1635
type: UnificationXref
id: REACT_4481
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4481.3

MMP13 fragment 20-76
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q8GWW6
name: MMP13(20-76)
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15787
feature: FragmentFeature4908
cellular location: GO:0005576
comment: Reactome DB_ID: 4196519
display name: MMP13

UnificationXref1636
type: UnificationXref
id: CHEBI:17855
db: ChEBI

O23507
type: Protein
entity reference: O23507
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13(20-54)
name: MMP13 fragment 20-54
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15792
feature: FragmentFeature4910
cellular location: GO:0005576
comment: Reactome DB_ID: 4196497
display name: MMP13

UnificationXref1637
type: UnificationXref
id: 549167
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=549167

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: MMP13(20-54)
name: MMP13 fragment 20-54
name: Q9ZUJ5
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15791
feature: FragmentFeature4909
cellular location: GO:0005576
comment: Reactome DB_ID: 4196496
display name: MMP13

UnificationXref1638
type: UnificationXref
id: REACT_22886
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_22886.2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q84W77
data source: Provenance1
name: MMP13(20-54)
name: MMP13 fragment 20-54
name: Collagenase 3
name: Q84W77
name: MMP13_HUMAN
xref: UnificationXref15796
feature: FragmentFeature4914
cellular location: GO:0005576
comment: Reactome DB_ID: 4196501
display name: MMP13

SequenceSite2939
type: SequenceSite
position status: EQUAL
sequence position: 460

UnificationXref1643
type: UnificationXref
id: REACT_98065
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_98065.9

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: MMP13(20-54)
name: MMP13 fragment 20-54
name: Q0WVU1
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15797
feature: FragmentFeature4915
cellular location: GO:0005576
comment: Reactome DB_ID: 4196502
display name: MMP13

UnificationXref1642
type: UnificationXref
id: 4181484
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181484

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04529
data source: Provenance1
name: MMP13(20-54)
name: MMP13 fragment 20-54
name: O04529
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15798
feature: FragmentFeature4916
cellular location: GO:0005576
comment: Reactome DB_ID: 4196503
display name: MMP13

UnificationXref1645
type: UnificationXref
id: REACT_110365
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_110365.9

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP13(20-54)
name: MMP13 fragment 20-54
name: Collagenase 3
name: MMP13_HUMAN
name: O48680
xref: UnificationXref15799
feature: FragmentFeature4917
cellular location: GO:0005576
comment: Reactome DB_ID: 4196504
display name: MMP13

UnificationXref1644
type: UnificationXref
id: 4199506
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199506

UnificationXref17579
type: UnificationXref
id: 4183824
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183824

SequenceSite2935
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2936
type: SequenceSite
position status: EQUAL
sequence position: 460

SequenceSite2937
type: SequenceSite
position status: EQUAL
sequence position: 412

UnificationXref1641
type: UnificationXref
id: 4181482
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181482

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: MMP13(20-54)
name: MMP13 fragment 20-54
name: Collagenase 3
name: Q5XF51
name: MMP13_HUMAN
xref: UnificationXref15795
feature: FragmentFeature4913
cellular location: GO:0005576
comment: Reactome DB_ID: 4196500
display name: MMP13

SequenceSite2938
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1640
type: UnificationXref
id: 4181481
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181481

UnificationXref17575
type: UnificationXref
id: 4183858
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183858

SequenceSite2931
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17576
type: UnificationXref
id: 4183859
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183859

SequenceSite2932
type: SequenceSite
position status: EQUAL
sequence position: 636

UnificationXref17577
type: UnificationXref
id: 4183860
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183860

SequenceSite2933
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17578
type: UnificationXref
id: 4183861
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183861

SequenceSite2934
type: SequenceSite
position status: EQUAL
sequence position: 385

UnificationXref17571
type: UnificationXref
id: 4183836
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183836

http://identifiers.org/pubmed/7378348
type: PublicationXref
id: 7378348
author: So, AG
author: Tan, CK
author: Downey, KM
author: Lee, MY
db: Pubmed
title: Purification of deoxyribonucleic acid polymerase delta from calf thymus: partial characterization of physical properties.
source: Biochemistry 19:2096-101
year: 1980

UnificationXref17572
type: UnificationXref
id: 4183837
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183837

UnificationXref17573
type: UnificationXref
id: 4183880
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183880

UnificationXref17574
type: UnificationXref
id: 4183857
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183857

SequenceSite2930
type: SequenceSite
position status: EQUAL
sequence position: 656

UnificationXref17581
type: UnificationXref
id: 4183874
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183874

UnificationXref17580
type: UnificationXref
id: 4183831
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183831

MMP13 fragment 20-76
type: Protein
entity reference: UniProt:Q5XF51
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13(20-76)
name: Collagenase 3
name: Q5XF51
name: MMP13_HUMAN
xref: UnificationXref15782
feature: FragmentFeature4903
cellular location: GO:0005576
comment: Reactome DB_ID: 4196514
display name: MMP13

MMP13 fragment 20-76
type: Protein
entity reference: Q8LET7
data source: Provenance1
name: Q8LET7
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13(20-76)
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15781
feature: FragmentFeature4902
cellular location: GO:0005576
comment: Reactome DB_ID: 4196513
display name: MMP13

MMP13 fragment 20-76
type: Protein
entity reference: O65340
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13(20-76)
name: Collagenase 3
name: O65340
name: MMP13_HUMAN
xref: UnificationXref15780
feature: FragmentFeature4901
cellular location: GO:0005576
comment: Reactome DB_ID: 4196512
display name: MMP13

MMP13 fragment 20-76
type: Protein
entity reference: O23507
data source: Provenance1
name: O23507
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13(20-76)
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15779
feature: FragmentFeature4900
cellular location: GO:0005576
comment: Reactome DB_ID: 4196511
display name: MMP13

UnificationXref1648
type: UnificationXref
id: REACT_11423
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_11423.2

MMP13 fragment 20-76
type: Protein
entity reference: Q9ZUJ5
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q9ZUJ5
name: MMP13(20-76)
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15778
feature: FragmentFeature4899
cellular location: GO:0005576
comment: Reactome DB_ID: 4196510
display name: MMP13

UnificationXref1649
type: UnificationXref
id: GO:0005758
db: GENE ONTOLOGY

Homologues of MMP13(20-76)
type: Protein
data source: Provenance1
member physical entity: MMP13 fragment 20-76
xref: UnificationXref15788
cellular location: GO:0005576
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4196520

UnificationXref1646
type: UnificationXref
id: CHEBI:17126
db: ChEBI

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GWW6
data source: Provenance1
name: Q8GWW6
name: MMP13 intermediate form 77-471
name: Collagenase 3
name: MMP13_HUMAN
name: MMP13(77-471)
xref: UnificationXref15776
feature: FragmentFeature4898
cellular location: GO:0005576
comment: Reactome DB_ID: 4196446
display name: MMP13

UnificationXref1647
type: UnificationXref
id: 201023
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=201023

MMP13 fragment 20-76
type: Protein
entity reference: O04529
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13(20-76)
name: O04529
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15785
feature: FragmentFeature4906
cellular location: GO:0005576
comment: Reactome DB_ID: 4196517
display name: MMP13

UnificationXref1656
type: UnificationXref
id: REACT_22875
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_22875.2

MMP13 fragment 20-76
type: Protein
entity reference: O48680
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13(20-76)
name: Collagenase 3
name: MMP13_HUMAN
name: O48680
xref: UnificationXref15786
feature: FragmentFeature4907
cellular location: GO:0005576
comment: Reactome DB_ID: 4196518
display name: MMP13

UnificationXref1655
type: UnificationXref
id: 549207
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=549207

MMP13 fragment 20-76
type: Protein
entity reference: Q84W77
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: MMP13(20-76)
name: Collagenase 3
name: Q84W77
name: MMP13_HUMAN
xref: UnificationXref15783
feature: FragmentFeature4904
cellular location: GO:0005576
comment: Reactome DB_ID: 4196515
display name: MMP13

UnificationXref1654
type: UnificationXref
id: REACT_11789
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_11789.2

MMP13 fragment 20-76
type: Protein
entity reference: Q0WVU1
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q0WVU1
name: MMP13(20-76)
name: Collagenase 3
name: MMP13_HUMAN
xref: UnificationXref15784
feature: FragmentFeature4905
cellular location: GO:0005576
comment: Reactome DB_ID: 4196516
display name: MMP13

UnificationXref1653
type: UnificationXref
id: 201050
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=201050

SequenceSite2948
type: SequenceSite
position status: EQUAL
sequence position: 188

UnificationXref1652
type: UnificationXref
id: REACT_11285
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_11285.2

SequenceSite2949
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1651
type: UnificationXref
id: 201034
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=201034

SequenceSite2946
type: SequenceSite
position status: EQUAL
sequence position: 88

UnificationXref1650
type: UnificationXref
id: CHEBI:17490
db: ChEBI

SequenceSite2947
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17588
type: UnificationXref
id: 4183797
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183797

SequenceSite2944
type: SequenceSite
position status: EQUAL
sequence position: 88

UnificationXref17589
type: UnificationXref
id: 4183798
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183798

SequenceSite2945
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17586
type: UnificationXref
id: 4183834
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183834

SequenceSite2942
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17587
type: UnificationXref
id: 4183796
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183796

SequenceSite2943
type: SequenceSite
position status: EQUAL
sequence position: 88

UnificationXref17584
type: UnificationXref
id: 4183832
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183832

SequenceSite2940
type: SequenceSite
position status: EQUAL
sequence position: 61

UnificationXref17585
type: UnificationXref
id: 4183833
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183833

SequenceSite2941
type: SequenceSite
position status: EQUAL
sequence position: 457

UnificationXref17582
type: UnificationXref
id: 4183875
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183875

UnificationXref17583
type: UnificationXref
id: 4183876
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183876

UnificationXref1614
type: UnificationXref
id: 4181445
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181445

UnificationXref1613
type: UnificationXref
id: Q8L7R3
db: UniProt

UnificationXref1616
type: UnificationXref
id: Q9LHN4
db: UniProt

UnificationXref1615
type: UnificationXref
id: 4181446
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181446

UnificationXref1618
type: UnificationXref
id: Q8L4Y2
db: UniProt

UnificationXref1617
type: UnificationXref
id: 4181450
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181450

UnificationXref1619
type: UnificationXref
id: 4181454
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181454

http://identifiers.org/pubmed/10681536
type: PublicationXref
id: 10681536
author: Gaither, LA
author: Eide, DJ
db: Pubmed
title: Functional expression of the human hZIP2 zinc transporter
source: J Biol Chem 275:5560-4
year: 2000

UnificationXref17510
type: UnificationXref
id: 4183867
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183867

SequenceSite2910
type: SequenceSite
position status: EQUAL
sequence position: 935

UnificationXref17512
type: UnificationXref
id: 4183825
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183825

SequenceSite2912
type: SequenceSite
position status: EQUAL
sequence position: 935

UnificationXref17511
type: UnificationXref
id: 4183868
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183868

SequenceSite2911
type: SequenceSite
position status: EQUAL
sequence position: 2

http://identifiers.org/pubmed/18367721
type: PublicationXref
id: 18367721
author: Skinner, SJ
author: Deleault, KM
author: Whitfield, ML
author: Brooks, SA
author: Gross, RH
author: Townley-Tilson, WH
author: Emmons, J
db: Pubmed
title: Identification of TTP mRNA targets in human dendritic cells reveals TTP as a critical regulator of dendritic cell maturation
source: RNA 14:888-902
year: 2008

UnificationXref17514
type: UnificationXref
id: 4183827
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183827

SequenceSite2914
type: SequenceSite
position status: EQUAL
sequence position: 935

UnificationXref17513
type: UnificationXref
id: 4183826
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183826

SequenceSite2913
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17516
type: UnificationXref
id: 4183812
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183812

SequenceSite2916
type: SequenceSite
position status: EQUAL
sequence position: 935

UnificationXref17515
type: UnificationXref
id: 4183895
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183895

SequenceSite2915
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17518
type: UnificationXref
id: 4183849
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183849

SequenceSite2918
type: SequenceSite
position status: EQUAL
sequence position: 935

UnificationXref1620
type: UnificationXref
id: 4181455
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181455

UnificationXref17517
type: UnificationXref
id: 4183848
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183848

SequenceSite2917
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref1621
type: UnificationXref
id: 4181456
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181456

UnificationXref1622
type: UnificationXref
id: 4181457
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181457

UnificationXref17519
type: UnificationXref
id: 4183850
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183850

SequenceSite2919
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref1623
type: UnificationXref
id: 4181458
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181458

Stoichiometry2101
type: Stoichiometry
physical entity: PhysicalEntity323
stoichiometric coefficient: 1.0

UnificationXref1627
type: UnificationXref
id: 4181462
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181462

Stoichiometry2102
type: Stoichiometry
physical entity: Protein2957
stoichiometric coefficient: 1.0

UnificationXref1626
type: UnificationXref
id: 4181461
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181461

UnificationXref1625
type: UnificationXref
id: 4181460
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181460

Stoichiometry2100
type: Stoichiometry
physical entity: Complex753
stoichiometric coefficient: 1.0

UnificationXref1624
type: UnificationXref
id: 4181459
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181459

UnificationXref1629
type: UnificationXref
id: 4181465
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181465

UnificationXref1628
type: UnificationXref
id: 4181463
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181463

Stoichiometry2109
type: Stoichiometry
physical entity: Homologues of ELN
stoichiometric coefficient: 10.0

Stoichiometry2107
type: Stoichiometry
physical entity: Complex761
stoichiometric coefficient: 1.0

Stoichiometry2108
type: Stoichiometry
physical entity: Homologues of ELN
stoichiometric coefficient: 10.0

Stoichiometry2105
type: Stoichiometry
physical entity: Protein4865
stoichiometric coefficient: 1.0

Stoichiometry2106
type: Stoichiometry
physical entity: Note: the coordinates are copied over from Homo sapiens.
stoichiometric coefficient: 1.0

Stoichiometry2103
type: Stoichiometry
physical entity: Complex762
stoichiometric coefficient: 1.0

Stoichiometry2104
type: Stoichiometry
physical entity: Complex680
stoichiometric coefficient: 1.0

UnificationXref17523
type: UnificationXref
id: 4183793
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183793

SequenceSite2923
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17522
type: UnificationXref
id: 4183853
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183853

SequenceSite2922
type: SequenceSite
position status: EQUAL
sequence position: 935

UnificationXref17521
type: UnificationXref
id: 4183852
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183852

SequenceSite2921
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17520
type: UnificationXref
id: 4183851
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183851

SequenceSite2920
type: SequenceSite
position status: EQUAL
sequence position: 935

UnificationXref17527
type: UnificationXref
id: 4183897
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183897

SequenceSite2927
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref17526
type: UnificationXref
id: 4183896
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183896

SequenceSite2926
type: SequenceSite
position status: EQUAL
sequence position: 935

UnificationXref1630
type: UnificationXref
id: REACT_113260
db: Reactome
id version: 8
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_113260.8

UnificationXref17525
type: UnificationXref
id: 4183795
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183795

SequenceSite2925
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref17524
type: UnificationXref
id: 4183794
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183794

SequenceSite2924
type: SequenceSite
position status: EQUAL
sequence position: 935

UnificationXref1633
type: UnificationXref
id: REACT_5036
db: Reactome
id version: 4
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5036.4

UnificationXref1634
type: UnificationXref
id: 76103
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=76103

Transport to the Golgi and subsequent modification
type: Pathway
data source: Provenance1
pathway component: REACT 135460.5
pathway component: REACT 128779.5
pathway component: REACT 32610.10
evidence: Evidence1385
xref: UnificationXref14551
xref: UnificationXref14550
pathway order: PathwayStep1358
pathway order: PathwayStep1364
pathway order: PathwayStep738
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

UnificationXref17529
type: UnificationXref
id: 4183899
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183899

SequenceSite2929
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1631
type: UnificationXref
id: CHEBI:37554
db: ChEBI

UnificationXref17528
type: UnificationXref
id: 4183898
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183898

SequenceSite2928
type: SequenceSite
position status: EQUAL
sequence position: 656

UnificationXref1632
type: UnificationXref
id: 75967
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=75967

UnificationXref17532
type: UnificationXref
id: 4183885
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183885

UnificationXref17531
type: UnificationXref
id: 4183884
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183884

UnificationXref17534
type: UnificationXref
id: 4183800
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183800

UnificationXref17533
type: UnificationXref
id: 4183886
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183886

UnificationXref17530
type: UnificationXref
id: 4183883
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183883

UnificationXref17539
type: UnificationXref
id: 4183871
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183871

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O48680
data source: Provenance1
name: MMP9 fragment 60-106
name: MMP9(60-106)
name: MMP9_HUMAN
name: Pro Matrix metalloproteinase-9 (MMP9)
xref: UnificationXref15751
feature: FragmentFeature4877
cellular location: GO:0005576
comment: Reactome DB_ID: 4196376
display name: O48680

UnificationXref1600
type: UnificationXref
id: 426755
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=426755

UnificationXref1601
type: UnificationXref
id: REACT_120138
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_120138.1

UnificationXref17536
type: UnificationXref
id: 4183802
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183802

UnificationXref17535
type: UnificationXref
id: 4183801
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183801

UnificationXref17538
type: UnificationXref
id: 4183870
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183870

UnificationXref17537
type: UnificationXref
id: 4183869
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183869

UnificationXref1609
type: UnificationXref
id: Q8S8S2
db: UniProt

UnificationXref1608
type: UnificationXref
id: 4181439
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181439

UnificationXref1607
type: UnificationXref
id: Q8LG31
db: UniProt

UnificationXref1606
type: UnificationXref
id: 4181435
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181435

UnificationXref1605
type: UnificationXref
id: O64646
db: UniProt

UnificationXref1604
type: UnificationXref
id: 4181427
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181427

UnificationXref1603
type: UnificationXref
id: 4181426
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181426

UnificationXref1602
type: UnificationXref
id: Q8GXU8
db: UniProt

UnificationXref17545
type: UnificationXref
id: 4183803
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183803

SequenceSite2901
type: SequenceSite
position status: EQUAL
sequence position: 43

UnificationXref17544
type: UnificationXref
id: 4183840
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183840

SequenceSite2900
type: SequenceSite
position status: EQUAL
sequence position: 587

UnificationXref17543
type: UnificationXref
id: 4183839
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183839

UnificationXref17542
type: UnificationXref
id: 4183838
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183838

UnificationXref17541
type: UnificationXref
id: 4183873
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183873

http://identifiers.org/pubmed/19261609
type: PublicationXref
id: 19261609
author: Vitvitsky, V
author: Singh, S
author: Banerjee, R
author: Zhu, W
author: Chiku, T
author: Padovani, D
db: Pubmed
title: H2S biogenesis by human cystathionine gamma-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia
source: J Biol Chem 284:11601-12
year: 2009

UnificationXref17540
type: UnificationXref
id: 4183872
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183872

SequenceSite2909
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref1611
type: UnificationXref
id: Q8GY20
db: UniProt

SequenceSite2908
type: SequenceSite
position status: EQUAL
sequence position: 587

UnificationXref1612
type: UnificationXref
id: 4181443
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181443

SequenceSite2907
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite2906
type: SequenceSite
position status: EQUAL
sequence position: 587

UnificationXref1610
type: UnificationXref
id: 4181441
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4181441

UnificationXref17549
type: UnificationXref
id: 4183829
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183829

SequenceSite2905
type: SequenceSite
position status: EQUAL
sequence position: 43

UnificationXref17548
type: UnificationXref
id: 4183828
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183828

SequenceSite2904
type: SequenceSite
position status: EQUAL
sequence position: 587

UnificationXref17547
type: UnificationXref
id: 4183805
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183805

SequenceSite2903
type: SequenceSite
position status: EQUAL
sequence position: 43

UnificationXref17546
type: UnificationXref
id: 4183804
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183804

SequenceSite2902
type: SequenceSite
position status: EQUAL
sequence position: 587

Stoichiometry2139
type: Stoichiometry
physical entity: Protein5971
stoichiometric coefficient: 1.0

Stoichiometry2138
type: Stoichiometry
physical entity: PhysicalEntity338
stoichiometric coefficient: 1.0

Stoichiometry2137
type: Stoichiometry
physical entity: Homologues of 2xMe-SNRPB
stoichiometric coefficient: 1.0

Stoichiometry2136
type: Stoichiometry
physical entity: Homologues of LSM2
stoichiometric coefficient: 1.0

Stoichiometry2135
type: Stoichiometry
physical entity: Homologues of TXNL4A
stoichiometric coefficient: 1.0

Stoichiometry2134
type: Stoichiometry
physical entity: Note: the coordinates are copied over from Homo sapiens.
stoichiometric coefficient: 1.0

Stoichiometry2133
type: Stoichiometry
physical entity: PhysicalEntity337
stoichiometric coefficient: 1.0

Stoichiometry2132
type: Stoichiometry
physical entity: PhysicalEntity336
stoichiometric coefficient: 1.0

Stoichiometry2131
type: Stoichiometry
physical entity: Complex359
stoichiometric coefficient: 1.0

Stoichiometry2130
type: Stoichiometry
physical entity: Complex391
stoichiometric coefficient: 1.0

Stoichiometry2148
type: Stoichiometry
physical entity: Protein6010
stoichiometric coefficient: 1.0

Stoichiometry2147
type: Stoichiometry
physical entity: Protein6005
stoichiometric coefficient: 1.0

Stoichiometry2149
type: Stoichiometry
physical entity: Protein6013
stoichiometric coefficient: 1.0

Stoichiometry2144
type: Stoichiometry
physical entity: Complex776
stoichiometric coefficient: 1.0

Stoichiometry2143
type: Stoichiometry
physical entity: Protein5987
stoichiometric coefficient: 1.0

Stoichiometry2146
type: Stoichiometry
physical entity: Protein5999
stoichiometric coefficient: 1.0

Stoichiometry2145
type: Stoichiometry
physical entity: Protein5991
stoichiometric coefficient: 1.0

Stoichiometry2140
type: Stoichiometry
physical entity: Protein5974
stoichiometric coefficient: 1.0

Stoichiometry2142
type: Stoichiometry
physical entity: Protein5982
stoichiometric coefficient: 1.0

Stoichiometry2141
type: Stoichiometry
physical entity: Protein5977
stoichiometric coefficient: 1.0

Stoichiometry2117
type: Stoichiometry
physical entity: PhysicalEntity333
stoichiometric coefficient: 1.0

Stoichiometry2116
type: Stoichiometry
physical entity: Complex416
stoichiometric coefficient: 1.0

Stoichiometry2115
type: Stoichiometry
physical entity: PhysicalEntity216
stoichiometric coefficient: 1.0

Stoichiometry2114
type: Stoichiometry
physical entity: PhysicalEntity333
stoichiometric coefficient: 1.0

Stoichiometry2119
type: Stoichiometry
physical entity: Complex416
stoichiometric coefficient: 1.0

Stoichiometry2118
type: Stoichiometry
physical entity: SmallMolecule1092
stoichiometric coefficient: 1.0

Stoichiometry2113
type: Stoichiometry
physical entity: Complex416
stoichiometric coefficient: 1.0

Stoichiometry2112
type: Stoichiometry
physical entity: PhysicalEntity216
stoichiometric coefficient: 1.0

Stoichiometry2111
type: Stoichiometry
physical entity: PhysicalEntity332
stoichiometric coefficient: 1.0

Stoichiometry2110
type: Stoichiometry
physical entity: Homologues of MMP13
stoichiometric coefficient: 3.0

UnificationXref17506
type: UnificationXref
id: 4183863
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183863

UnificationXref17507
type: UnificationXref
id: 4183864
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183864

UnificationXref17508
type: UnificationXref
id: 4183865
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183865

UnificationXref17509
type: UnificationXref
id: 4183866
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183866

UnificationXref17502
type: UnificationXref
id: 4183789
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183789

UnificationXref17503
type: UnificationXref
id: 4183791
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183791

UnificationXref17504
type: UnificationXref
id: REACT_139532
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_139532.5

UnificationXref17505
type: UnificationXref
id: 4183862
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183862

UnificationXref17500
type: UnificationXref
id: 4199641
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199641

UnificationXref17501
type: UnificationXref
id: REACT_29102
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_29102.10

Stoichiometry2126
type: Stoichiometry
physical entity: PhysicalEntity216
stoichiometric coefficient: 1.0

Stoichiometry2125
type: Stoichiometry
physical entity: PhysicalEntity335
stoichiometric coefficient: 1.0

Stoichiometry2128
type: Stoichiometry
physical entity: Protein3325
stoichiometric coefficient: 1.0

Stoichiometry2127
type: Stoichiometry
physical entity: Complex416
stoichiometric coefficient: 1.0

Stoichiometry2129
type: Stoichiometry
physical entity: Protein3320
stoichiometric coefficient: 1.0

Stoichiometry2120
type: Stoichiometry
physical entity: Complex768
stoichiometric coefficient: 1.0

Stoichiometry2122
type: Stoichiometry
physical entity: PhysicalEntity216
stoichiometric coefficient: 1.0

Stoichiometry2121
type: Stoichiometry
physical entity: PhysicalEntity216
stoichiometric coefficient: 1.0

Stoichiometry2124
type: Stoichiometry
physical entity: PhysicalEntity334
stoichiometric coefficient: 1.0

Stoichiometry2123
type: Stoichiometry
physical entity: Complex416
stoichiometric coefficient: 1.0

RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
type: Pathway
data source: Provenance1
pathway component: REACT 84770.9
pathway component: REACT 95463.9
evidence: Evidence841
xref: UnificationXref9929
xref: UnificationXref9930
pathway order: PathwayStep832
pathway order: PathwayStep822
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/18767960
type: PublicationXref
id: 18767960
author: Antonellis, A
author: Green, ED
db: Pubmed
title: The role of aminoacyl-tRNA synthetases in genetic diseases
source: Annu Rev Genomics Hum Genet 9:87-107
year: 2008

Stoichiometry2171
type: Stoichiometry
physical entity: Protein6030
stoichiometric coefficient: 1.0

Stoichiometry2170
type: Stoichiometry
physical entity: PhysicalEntity62
stoichiometric coefficient: 1.0

Stoichiometry2178
type: Stoichiometry
physical entity: PhysicalEntity70
stoichiometric coefficient: 1.0

Stoichiometry2179
type: Stoichiometry
physical entity: Protein2555
stoichiometric coefficient: 1.0

Stoichiometry2176
type: Stoichiometry
physical entity: PhysicalEntity345
stoichiometric coefficient: 1.0

Stoichiometry2177
type: Stoichiometry
physical entity: PhysicalEntity346
stoichiometric coefficient: 1.0

Stoichiometry2174
type: Stoichiometry
physical entity: Protein2506
stoichiometric coefficient: 1.0

Stoichiometry2175
type: Stoichiometry
physical entity: PhysicalEntity344
stoichiometric coefficient: 1.0

Stoichiometry2172
type: Stoichiometry
physical entity: Protein6034
stoichiometric coefficient: 1.0

Stoichiometry2173
type: Stoichiometry
physical entity: Protein6064
stoichiometric coefficient: 1.0

Stoichiometry2180
type: Stoichiometry
physical entity: PhysicalEntity347
stoichiometric coefficient: 1.0

Stoichiometry2182
type: Stoichiometry
physical entity: PhysicalEntity348
stoichiometric coefficient: 1.0

Stoichiometry2181
type: Stoichiometry
physical entity: Protein2489
stoichiometric coefficient: 1.0

Stoichiometry2187
type: Stoichiometry
physical entity: PhysicalEntity351
stoichiometric coefficient: 1.0

Stoichiometry2188
type: Stoichiometry
physical entity: PhysicalEntity352
stoichiometric coefficient: 1.0

Stoichiometry2189
type: Stoichiometry
physical entity: PhysicalEntity353
stoichiometric coefficient: 1.0

Stoichiometry2183
type: Stoichiometry
physical entity: PhysicalEntity349
stoichiometric coefficient: 1.0

Stoichiometry2184
type: Stoichiometry
physical entity: PhysicalEntity350
stoichiometric coefficient: 1.0

UniProt:F4JLM5
type: ProteinReference
xref: UnificationXref16644
organism: Arabidopsis thaliana

Stoichiometry2185
type: Stoichiometry
physical entity: Protein6065
stoichiometric coefficient: 1.0

Stoichiometry2186
type: Stoichiometry
physical entity: Protein2585
stoichiometric coefficient: 1.0

UnificationXref1680
type: UnificationXref
id: 4186609
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186609

UnificationXref1681
type: UnificationXref
id: 4186611
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186611

UnificationXref1688
type: UnificationXref
id: 4186580
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186580

UnificationXref1689
type: UnificationXref
id: Q84VQ1
db: UniProt

UnificationXref1686
type: UnificationXref
id: 4186620
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186620

UnificationXref1687
type: UnificationXref
id: AT1G09020.1
db: Ensembl

http://identifiers.org/pubmed/9305914
type: PublicationXref
id: 9305914
author: Ishimi, Y
db: Pubmed
title: A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex.
source: J Biol Chem 272:24508-13
year: 1997

UnificationXref1684
type: UnificationXref
id: 4186617
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186617

UnificationXref1685
type: UnificationXref
id: 4186619
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186619

UnificationXref1682
type: UnificationXref
id: 4186613
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186613

UnificationXref1683
type: UnificationXref
id: 4186615
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186615

Stoichiometry2152
type: Stoichiometry
physical entity: PhysicalEntity340
stoichiometric coefficient: 1.0

Stoichiometry2153
type: Stoichiometry
physical entity: Complex775
stoichiometric coefficient: 1.0

Stoichiometry2150
type: Stoichiometry
physical entity: PhysicalEntity339
stoichiometric coefficient: 1.0

Stoichiometry2151
type: Stoichiometry
physical entity: Protein6014
stoichiometric coefficient: 1.0

Stoichiometry2156
type: Stoichiometry
physical entity: Complex776
stoichiometric coefficient: 1.0

Stoichiometry2157
type: Stoichiometry
physical entity: PhysicalEntity341
stoichiometric coefficient: 1.0

Stoichiometry2154
type: Stoichiometry
physical entity: Homologues of LSM2
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/14638695
type: PublicationXref
id: 14638695
author: Lu, M
author: Haney, LB
author: Brugnera, E
author: Hengartner, MO
author: Tosello-Trampont, AC
author: Klingele, D
author: Ravichandran, KS
author: Kinchen, JM
author: Chen, Q
author: Grimsley, CM
db: Pubmed
title: Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration
source: J Biol Chem 279:6087-97
year: 2004

Stoichiometry2155
type: Stoichiometry
physical entity: Protein6023
stoichiometric coefficient: 1.0

UnificationXref1679
type: UnificationXref
id: 4186607
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186607

Stoichiometry2158
type: Stoichiometry
physical entity: Protein6014
stoichiometric coefficient: 1.0

Stoichiometry2159
type: Stoichiometry
physical entity: Complex778
stoichiometric coefficient: 1.0

UnificationXref1690
type: UnificationXref
id: 4186574
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186574

UnificationXref1691
type: UnificationXref
id: Q9SCY5
db: UniProt

UnificationXref1692
type: UnificationXref
id: 4186575
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186575

UnificationXref1697
type: UnificationXref
id: MOD:00047
db: MOD

UnificationXref1698
type: UnificationXref
id: 4186584
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186584

UnificationXref1699
type: UnificationXref
id: P92958
db: UniProt

UnificationXref1693
type: UnificationXref
id: AT2G28060.1
db: Ensembl

UnificationXref1694
type: UnificationXref
id: 4186576
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186576

Stoichiometry2160
type: Stoichiometry
physical entity: Protein6023
stoichiometric coefficient: 1.0

UnificationXref1695
type: UnificationXref
id: 4186577
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186577

UnificationXref1696
type: UnificationXref
id: Q9ZRA0
db: UniProt

Stoichiometry2161
type: Stoichiometry
physical entity: PhysicalEntity342
stoichiometric coefficient: 1.0

Stoichiometry2162
type: Stoichiometry
physical entity: Protein6014
stoichiometric coefficient: 1.0

Stoichiometry2163
type: Stoichiometry
physical entity: Complex779
stoichiometric coefficient: 1.0

Stoichiometry2164
type: Stoichiometry
physical entity: Complex777
stoichiometric coefficient: 1.0

Stoichiometry2165
type: Stoichiometry
physical entity: Protein6026
stoichiometric coefficient: 1.0

Stoichiometry2166
type: Stoichiometry
physical entity: PhysicalEntity343
stoichiometric coefficient: 1.0

Stoichiometry2167
type: Stoichiometry
physical entity: Protein2573
stoichiometric coefficient: 1.0

Stoichiometry2168
type: Stoichiometry
physical entity: Protein2576
stoichiometric coefficient: 1.0

Stoichiometry2169
type: Stoichiometry
physical entity: Protein2597
stoichiometric coefficient: 1.0

SequenceSite5696
type: SequenceSite
position status: EQUAL
sequence position: 211

eIF3 and eIF1A bind to the 40S subunit
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1265
xref: UnificationXref13312
xref: UnificationXref13313
left: Complex376
left: Complex380
left: Protein3116
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex642

SequenceSite5695
type: SequenceSite
position status: EQUAL
sequence position: 1

De novo formation of eIF2:GTP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1267
xref: UnificationXref13317
xref: UnificationXref13316
left: SmallMolecule460
left: Complex379
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex378

SequenceSite5698
type: SequenceSite
position status: EQUAL
sequence position: 1872

Autocleavage of ESPL1 (Separase)
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1258
xref: UnificationXref13296
xref: UnificationXref13297
left: Protein4714
display name: Autocleavage of Separin
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex640

SequenceSite5697
type: SequenceSite
position status: EQUAL
sequence position: 1

Release of 40S and 60S subunits from the 80S ribosome
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1264
xref: UnificationXref13310
xref: UnificationXref13309
left: Complex641
left: Protein3116
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex380
right: Protein3116
right: Complex370

SequenceSite2970
type: SequenceSite
position status: EQUAL
sequence position: 496

SequenceSite5692
type: SequenceSite
position status: EQUAL
sequence position: 782

SequenceSite5691
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5694
type: SequenceSite
position status: EQUAL
sequence position: 211

Met-tRNAi binds to eIF2:GTP to form the ternary complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1268
xref: UnificationXref13318
xref: UnificationXref13319
left: Complex378
left: PhysicalEntity85
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex377

SequenceSite5693
type: SequenceSite
position status: EQUAL
sequence position: 1

Formation of the 43S pre-initiation complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1269
xref: UnificationXref13322
xref: UnificationXref13321
left: Complex377
left: Complex642
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex375

SequenceSite5690
type: SequenceSite
position status: EQUAL
sequence position: 782

SequenceSite2979
type: SequenceSite
position status: EQUAL
sequence position: 496

SequenceSite2973
type: SequenceSite
position status: EQUAL
sequence position: 496

Formation of the cap-binding eIF4F complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1271
xref: UnificationXref13326
xref: UnificationXref13325
left: Complex374
left: Protein2957
left: Protein2952
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex373

SequenceSite2974
type: SequenceSite
position status: EQUAL
sequence position: 314

SequenceSite2971
type: SequenceSite
position status: EQUAL
sequence position: 314

SequenceSite2972
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite2977
type: SequenceSite
position status: EQUAL
sequence position: 314

SequenceSite5699
type: SequenceSite
position status: EQUAL
sequence position: 1

eIF5B:GTP is hydrolyzed and released
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1277
xref: UnificationXref13387
xref: UnificationXref13388
left: Complex646
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex649
right: SmallMolecule31
right: Complex648

SequenceSite2978
type: SequenceSite
position status: EQUAL
sequence position: 2

Start codon recognition
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1275
xref: UnificationXref13346
xref: UnificationXref13347
left: PhysicalEntity258
left: Complex645
left: Protein4726
left: Protein3116
left: Complex379
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity258
right: Complex645
right: Protein4726
right: Protein3116
right: Complex379

SequenceSite2975
type: SequenceSite
position status: EQUAL
sequence position: 2

Ribosomal scanning
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1274
xref: UnificationXref13339
xref: UnificationXref13338
left: SmallMolecule11
left: Complex645
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex645
right: SmallMolecule14
right: SmallMolecule31

SequenceSite2976
type: SequenceSite
position status: EQUAL
sequence position: 496

eIF4F binds to mRNP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1272
xref: UnificationXref13331
xref: UnificationXref13332
left: Complex373
left: Complex643
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex644

The 60S subunit joins the translation initiation complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1278
xref: UnificationXref13391
xref: UnificationXref13390
left: Complex647
left: Complex650
left: Complex370
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex646

SequenceSite5687
type: SequenceSite
position status: EQUAL
sequence position: 1

Formation of eIF2:GDP:eIF2B intermediate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1280
xref: UnificationXref13440
xref: UnificationXref13439
left: Complex651
left: Complex652
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex653

SequenceSite5686
type: SequenceSite
position status: EQUAL
sequence position: 462

eIF2 activation
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1281
xref: UnificationXref13441
xref: UnificationXref13442
left: Complex653
left: SmallMolecule460
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex378
right: Complex652
right: SmallMolecule486

SequenceSite5685
type: SequenceSite
position status: EQUAL
sequence position: 1

Synthesis of nascent polypeptide containing signal sequence
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1285
xref: UnificationXref13453
xref: UnificationXref13452
left: Complex641
left: PhysicalEntity155
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex654

SequenceSite5684
type: SequenceSite
position status: EQUAL
sequence position: 462

Association of a nascent polypeptide:mRNA:ribosome complex with a signal recognition particle (SRP)
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1286
xref: UnificationXref13484
xref: UnificationXref13483
left: Complex655
left: Complex654
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex656

SequenceSite5683
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5682
type: SequenceSite
position status: EQUAL
sequence position: 462

SequenceSite2981
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite5681
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2980
type: SequenceSite
position status: EQUAL
sequence position: 314

SequenceSite5680
type: SequenceSite
position status: EQUAL
sequence position: 462

SequenceSite2982
type: SequenceSite
position status: EQUAL
sequence position: 496

SequenceSite2983
type: SequenceSite
position status: EQUAL
sequence position: 314

Signal peptide cleavage from ribosome-associated nascent protein
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1288
EC number: 3.4.21
xref: UnificationXref13587
xref: UnificationXref13588
left: Complex659
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity268
right: Complex664

SequenceSite2984
type: SequenceSite
position status: EQUAL
sequence position: 2

The SRP receptor binds the SRP:nascent peptide:ribosome complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1287
xref: UnificationXref13498
xref: UnificationXref13499
left: Complex656
left: Complex657
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex658

SequenceSite2985
type: SequenceSite
position status: EQUAL
sequence position: 496

eEF1A:GTP:aminoacyl tRNA ternary complex formation.
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1291
xref: UnificationXref13659
xref: UnificationXref13660
left: SmallMolecule993
left: Complex667
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex668

SequenceSite2986
type: SequenceSite
position status: EQUAL
sequence position: 314

eEF1A complexes with GTP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1290
xref: UnificationXref13595
xref: UnificationXref13594
left: Protein4838
left: SmallMolecule460
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex667

SequenceSite2987
type: SequenceSite
position status: EQUAL
sequence position: 2

Hydrolysis of eEF1A:GTP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1293
EC number: 3.6.5.1
EC number: 3.6.5.3
EC number: 3.6.5.2
EC number: 3.6.5.4
xref: UnificationXref13666
xref: UnificationXref13667
left: Complex669
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex671
right: Complex670
right: SmallMolecule31

SequenceSite2988
type: SequenceSite
position status: EQUAL
sequence position: 496

SequenceSite5688
type: SequenceSite
position status: EQUAL
sequence position: 462

Aminoacyl-tRNA binds to the ribosome at the A-site
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1292
xref: UnificationXref13663
xref: UnificationXref13662
left: Complex668
left: Complex648
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex669

SequenceSite2989
type: SequenceSite
position status: EQUAL
sequence position: 314

SequenceSite5689
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite2992
type: SequenceSite
position status: EQUAL
sequence position: 314

SequenceSite2991
type: SequenceSite
position status: EQUAL
sequence position: 496

SequenceSite2990
type: SequenceSite
position status: EQUAL
sequence position: 2

UniProt:F4K2E9
type: ProteinReference
xref: UnificationXref8167
organism: Arabidopsis thaliana

SequenceSite2999
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite2997
type: SequenceSite
position status: EQUAL
sequence position: 496

SequenceSite2998
type: SequenceSite
position status: EQUAL
sequence position: 314

SequenceSite2995
type: SequenceSite
position status: EQUAL
sequence position: 314

SequenceSite2996
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite2993
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite2994
type: SequenceSite
position status: EQUAL
sequence position: 496

Dephosphorylation of CK2-modified condensin I
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1253
EC number: 3.1.3.16
xref: UnificationXref13267
xref: UnificationXref13266
participant stoichiometry: Stoichiometry1729
participant stoichiometry: Stoichiometry1728
left: Complex635
left: SmallMolecule48
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex634
right: SmallMolecule31

CK2 phosphorylates condensin I subunits
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1252
xref: UnificationXref13262
xref: UnificationXref13263
participant stoichiometry: Stoichiometry1719
participant stoichiometry: Stoichiometry1718
left: SmallMolecule11
left: Complex634
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex635
right: SmallMolecule14

Degradation of multiubiquitinated Securin
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1257
xref: UnificationXref13280
xref: UnificationXref13279
participant stoichiometry: Stoichiometry1737
left: Complex639
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3409
right: Complex638

Ubiquitination of Securin by phospho-APC/C:Cdc20 complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1256
EC number: 6.3.2.19
xref: UnificationXref13277
xref: UnificationXref13278
xref: RelationshipXref1066
participant stoichiometry: Stoichiometry1730
left: Complex637
left: Protein3409
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex639

http://identifiers.org/pubmed/12949583
type: PublicationXref
id: 12949583
author: van den Bosch, M
author: Lowndes, NF
author: Bree, RT
db: Pubmed
title: The MRN complex: coordinating and mediating the response to broken chromosomes.
source: EMBO Rep 4:844-9
year: 2003

UniProt:P20115
type: ProteinReference
xref: UnificationXref4276
organism: Arabidopsis thaliana

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04308
data source: Provenance1
name: Mitochondrial-processing peptidase subunit alpha
name: O04308
name: MPPA_HUMAN
xref: UnificationXref14742
feature: FragmentFeature4348
cellular location: GO:0005759
comment: Reactome DB_ID: 4195234
display name: PMPCA

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZU25
data source: Provenance1
name: Mitochondrial-processing peptidase subunit alpha
name: MPPA_HUMAN
name: Q9ZU25
xref: UnificationXref14740
feature: FragmentFeature4347
cellular location: GO:0005759
comment: Reactome DB_ID: 4195230
display name: PMPCA

Homologues of PMPCA
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14743
cellular location: GO:0005759
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4195235

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9C5S2
data source: Provenance1
name: IRE1
name: Q9C5S2
xref: UnificationXref14771
feature: FragmentFeature4351
cellular location: GO:0005789
comment: Reactome DB_ID: 4188932
display name: ERN1

Homologues of ERN1
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q8RX75
xref: UnificationXref14790
cellular location: GO:0005789
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4188955

Endoplasmin
type: Protein
entity reference: Q9STX5
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: ENPL_HUMAN
name: HSP90B1
xref: UnificationXref14763
feature: FragmentFeature4350
cellular location: GO:0005788
comment: Reactome DB_ID: 4197338
display name: Q9STX5

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q42290
data source: Provenance1
name: Mitochondrial-processing peptidase subunit beta
name: Q42290
name: MPPB_HUMAN
xref: UnificationXref14745
feature: FragmentFeature4349
cellular location: GO:0005759
comment: Reactome DB_ID: 4195239
display name: PMPCB

Platelet activation, signaling and aggregation
type: Pathway
data source: Provenance1
pathway component: REACT 95050.9
pathway component: REACT 31295.10
pathway component: REACT 112297.8
pathway component: REACT 156131.3
evidence: Evidence1069
xref: UnificationXref11806
xref: UnificationXref11805
xref: RelationshipXref1046
pathway order: PathwayStep1043
pathway order: PathwayStep1045
pathway order: PathwayStep1056
pathway order: PathwayStep1049
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

2'-deoxyinosine
type: SmallMoleculeReference
name: deoxyinosine
name: 2'-deoxyinosine [ChEBI:28997]
xref: UnificationXref4626

UnificationXref1700
type: UnificationXref
id: 4186585
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186585

UnificationXref1706
type: UnificationXref
id: 4186621
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186621

UnificationXref1705
type: UnificationXref
id: 4186588
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186588

UnificationXref1708
type: UnificationXref
id: REACT_101641
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_101641.9

UnificationXref1707
type: UnificationXref
id: 4186623
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186623

UnificationXref1702
type: UnificationXref
id: 4186586
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186586

UnificationXref1701
type: UnificationXref
id: Q38997
db: UniProt

UnificationXref1704
type: UnificationXref
id: 4186587
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186587

UnificationXref1703
type: UnificationXref
id: Q9FLZ3
db: UniProt

UnificationXref1709
type: UnificationXref
id: 4199510
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199510

UniProt:F4K2K3
type: ProteinReference
xref: UnificationXref7769
organism: Arabidopsis thaliana

UnificationXref1710
type: UnificationXref
id: REACT_32410
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_32410.10

UnificationXref1711
type: UnificationXref
id: CHEBI:15345
db: ChEBI

Q39011
type: Protein
entity reference: Q39011
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Glycogen synthase kinase-3 alpha
name: KG3A_HUMAN
name: GSK3A(1-483)
xref: UnificationXref14860
feature: FragmentFeature4384
cellular location: GO:0005829
comment: Reactome DB_ID: 4185434
display name: GSK3A

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: P43289
data source: Provenance1
name: P43289
name: Glycogen synthase kinase-3 alpha
name: KG3A_HUMAN
name: GSK3A(1-483)
xref: UnificationXref14862
feature: FragmentFeature4385
cellular location: GO:0005829
comment: Reactome DB_ID: 4185438
display name: GSK3A

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8VZD5
data source: Provenance1
name: Q8VZD5
name: Glycogen synthase kinase-3 alpha
name: KG3A_HUMAN
name: GSK3A(1-483)
xref: UnificationXref14864
feature: FragmentFeature4386
cellular location: GO:0005829
comment: Reactome DB_ID: 4185442
display name: GSK3A

SAM50 Complex Inserts Proteins into Mitochondrial Outer Membrane
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1390
xref: UnificationXref14645
xref: UnificationXref14644
left: PhysicalEntity290
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity291

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q39012
data source: Provenance1
name: Q39012
name: Glycogen synthase kinase-3 alpha
name: KG3A_HUMAN
name: GSK3A(1-483)
xref: UnificationXref14866
feature: FragmentFeature4387
cellular location: GO:0005829
comment: Reactome DB_ID: 4185446
display name: GSK3A

Homologues of HYOU1
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: F4JMJ1
xref: UnificationXref14878
cellular location: GO:0005788
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4197219

MPP Cleaves Presequence of Inner Membrane Precursors
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1392
EC number: 3.4.24
xref: UnificationXref14748
xref: UnificationXref14747
left: Complex720
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex723

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WM51
data source: Provenance1
name: HYOU1_HUMAN
name: Hypoxia up-regulated protein 1
name: Q0WM51
xref: UnificationXref14871
feature: FragmentFeature4388
cellular location: GO:0005788
comment: Reactome DB_ID: 4197212
display name: HYOU1

TIMM22 Inserts Proteins into Inner Membrane
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1391
xref: UnificationXref14673
xref: UnificationXref14674
left: PhysicalEntity292
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity293

F4JMJ1
type: Protein
entity reference: UniProt:F4JMJ1
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: HYOU1_HUMAN
name: Hypoxia up-regulated protein 1
xref: UnificationXref14873
feature: FragmentFeature4389
cellular location: GO:0005788
comment: Reactome DB_ID: 4197214
display name: HYOU1

Dimerization of IRE1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1400
xref: UnificationXref14793
xref: UnificationXref14792
participant stoichiometry: Stoichiometry1993
left: Homologues of ERN1
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex727

MPP Cleaves Presequence of Matrix Precursors
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1393
EC number: 3.4.24
xref: UnificationXref14754
xref: UnificationXref14753
left: Complex725
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex726

ADP Binding by Phosphorylated IRE1 Homodimer
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1402
xref: UnificationXref14811
xref: UnificationXref14812
participant stoichiometry: Stoichiometry1998
left: SmallMolecule14
left: Complex728
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex729

Autophosphorylation of IRE1 dimer
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1401
EC number: 2.7.11
xref: UnificationXref14806
xref: UnificationXref14807
participant stoichiometry: Stoichiometry1996
participant stoichiometry: Stoichiometry1995
left: SmallMolecule11
left: Complex727
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule14
right: Complex728

Binding of Lsm1-7 Complex to Deadenylated mRNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1432
xref: UnificationXref15085
xref: UnificationXref15086
left: PhysicalEntity301
left: Complex732
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex733

3' to 5' Exoribonuclease Digestion of mRNA by the Exosome Complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1430
xref: UnificationXref15031
xref: UnificationXref15030
left: PhysicalEntity301
left: SmallMolecule48
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule322
right: SmallMolecule86
right: SmallMolecule489
right: PhysicalEntity302
right: SmallMolecule18

AUF1(hnRNP D0) Dimers Bind AU-rich Element in 3' UTR of Transcripts
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1435
xref: UnificationXref15189
xref: UnificationXref15190
participant stoichiometry: Stoichiometry2024
left: Complex734
left: PhysicalEntity305
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex737

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q39019
data source: Provenance1
name: Q39019
name: Glycogen synthase kinase-3 alpha
name: KG3A_HUMAN
name: GSK3A(1-483)
xref: UnificationXref14854
feature: FragmentFeature4381
cellular location: GO:0005829
comment: Reactome DB_ID: 4185422
display name: GSK3A

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FVS6
data source: Provenance1
name: Q9FVS6
name: Glycogen synthase kinase-3 alpha
name: KG3A_HUMAN
name: GSK3A(1-483)
xref: UnificationXref14856
feature: FragmentFeature4382
cellular location: GO:0005829
comment: Reactome DB_ID: 4185426
display name: GSK3A

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: P43288
data source: Provenance1
name: P43288
name: Glycogen synthase kinase-3 alpha
name: KG3A_HUMAN
name: GSK3A(1-483)
xref: UnificationXref14858
feature: FragmentFeature4383
cellular location: GO:0005829
comment: Reactome DB_ID: 4185430
display name: GSK3A

http://identifiers.org/pubmed/12123609
type: PublicationXref
id: 12123609
author: Snider, WD
author: Zhong, J
author: Markus, A
db: Pubmed
title: Raf and akt mediate distinct aspects of sensory axon growth
source: Neuron 35:65-76
year: 2002

http://identifiers.org/pubmed/10958673
type: PublicationXref
id: 10958673
author: Yoshida, H
author: Haze, K
author: Yura, T
author: Yanagi, H
author: Mori, K
author: Okada, T
author: Negishi, M
db: Pubmed
title: ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response
source: Mol Cell Biol 20:6755-67
year: 2000

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SJL6
data source: Provenance1
name: Q9SJL6
name: Golgi SNAP receptor complex member 2
name: GOSR2_HUMAN
xref: UnificationXref14841
feature: FragmentFeature4376
cellular location: GO:0000139
comment: Reactome DB_ID: 4197322
display name: GOSR2

http://identifiers.org/pubmed/18772128
type: PublicationXref
id: 18772128
author: Riekhof, WR
author: Voelker, DR
author: Gijon, MA
author: Zarini, S
author: Murphy, RC
db: Pubmed
title: Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils
source: J Biol Chem 283:30235-45
year: 2008

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FK28
data source: Provenance1
name: Q9FK28
name: Golgi SNAP receptor complex member 2
name: GOSR2_HUMAN
xref: UnificationXref14843
feature: FragmentFeature4377
cellular location: GO:0000139
comment: Reactome DB_ID: 4197326
display name: GOSR2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q38936
data source: Provenance1
name: Q38936
name: FK506-binding protein 14
name: FKB14_HUMAN
xref: UnificationXref14832
feature: FragmentFeature4375
cellular location: GO:0005788
comment: Reactome DB_ID: 4197268
display name: FKBP14

Homologues of GOSR2
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14844
cellular location: GO:0000139
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4197327

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O23145
data source: Provenance1
name: O23145
name: Glycogen synthase kinase-3 alpha
name: KG3A_HUMAN
name: GSK3A(1-483)
xref: UnificationXref14850
feature: FragmentFeature4379
cellular location: GO:0005829
comment: Reactome DB_ID: 4185414
display name: GSK3A

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q96287
data source: Provenance1
name: Q96287
name: Glycogen synthase kinase-3 alpha
name: KG3A_HUMAN
name: GSK3A(1-483)
xref: UnificationXref14852
feature: FragmentFeature4380
cellular location: GO:0005829
comment: Reactome DB_ID: 4185418
display name: GSK3A

Homologues of GSK3A(1-483)
type: Protein
data source: Provenance1
member physical entity: Q39011
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q39010
xref: UnificationXref14867
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4185447

Q39010
type: Protein
entity reference: Q39010
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Glycogen synthase kinase-3 alpha
name: KG3A_HUMAN
name: GSK3A(1-483)
xref: UnificationXref14848
feature: FragmentFeature4378
cellular location: GO:0005829
comment: Reactome DB_ID: 4185410
display name: GSK3A

Homologues of FKBP14
type: Protein
data source: Provenance1
member physical entity: Q38935
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14833
cellular location: GO:0005788
comment: Reactome DB_ID: 4197269
comment: Converted from EntitySet in Reactome

Q38935
type: Protein
entity reference: Q38935
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: FK506-binding protein 14
name: FKB14_HUMAN
xref: UnificationXref14830
feature: FragmentFeature4374
cellular location: GO:0005788
comment: Reactome DB_ID: 4197264
display name: FKBP14

UniProt:Q94LW7
type: ProteinReference
xref: UnificationXref11902
organism: Arabidopsis thaliana

UniProt:Q94LW6
type: ProteinReference
xref: UnificationXref675
organism: Arabidopsis thaliana

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SR96
data source: Provenance1
name: Q9SR96
name: DNAJB9
name: ERdj4
xref: UnificationXref14824
feature: FragmentFeature4373
cellular location: GO:0005789
comment: Reactome DB_ID: 4197293
display name: MDG1

phospho-p-S724-ERN1
type: Protein
entity reference: Q8RX75
data source: Provenance1
xref: UnificationXref14802
feature: FragmentFeature4369
feature: ModificationFeature381
cellular location: GO:0005789
comment: Reactome DB_ID: 4188974

Addition of the first glucose to the N-glycan precursor by ALG6
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1358
xref: UnificationXref14300
xref: UnificationXref14299
left: SmallMolecule1054
left: SmallMolecule1055
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1050
right: SmallMolecule1056

phospho-p-S724-ERN1
type: Protein
entity reference: Q9SF12
data source: Provenance1
xref: UnificationXref14803
feature: ModificationFeature382
feature: FragmentFeature4370
cellular location: GO:0005789
comment: Reactome DB_ID: 4188976

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9CA92
data source: Provenance1
name: Q9CA92
name: DDX11_HUMAN
name: Probable ATP-dependent RNA helicase DDX11
xref: UnificationXref14816
feature: FragmentFeature4371
cellular location: GO:0005654
comment: Reactome DB_ID: 4197274
display name: DDX11

Addition of a third glucose to the N-glycan precursor by an ALG10 homologue
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1360
xref: UnificationXref14314
xref: UnificationXref14313
left: SmallMolecule1055
left: SmallMolecule1057
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1050
right: SmallMolecule1058

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LZK5
data source: Provenance1
name: DNAJB11
name: ERdj3
name: Q9LZK5
xref: UnificationXref14820
feature: FragmentFeature4372
cellular location: GO:0005788
comment: Reactome DB_ID: 4197224
display name: HEDJ

Addition of a second glucose to the N-glycan precursor by ALG8
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1359
xref: UnificationXref14307
xref: UnificationXref14306
left: SmallMolecule1055
left: SmallMolecule1056
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1050
right: SmallMolecule1057

phospho-p-S724-ERN1
type: Protein
entity reference: F4KH40
data source: Provenance1
xref: UnificationXref14798
feature: FragmentFeature4365
feature: ModificationFeature377
cellular location: GO:0005789
comment: Reactome DB_ID: 4188966

phospho-p-S724-ERN1
type: Protein
entity reference: Q0WPT1
data source: Provenance1
xref: UnificationXref14799
feature: ModificationFeature378
feature: FragmentFeature4366
cellular location: GO:0005789
comment: Reactome DB_ID: 4188968

phospho-p-S724-ERN1
type: Protein
entity reference: Q94IG5
data source: Provenance1
xref: UnificationXref14800
feature: ModificationFeature379
feature: FragmentFeature4367
cellular location: GO:0005789
comment: Reactome DB_ID: 4188970

phospho-p-S724-ERN1
type: Protein
entity reference: F4KH41
data source: Provenance1
xref: UnificationXref14801
feature: FragmentFeature4368
feature: ModificationFeature380
cellular location: GO:0005789
comment: Reactome DB_ID: 4188972

Trimming of the second mannose on the A branch
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1367
EC number: 3.2.1.24
xref: UnificationXref14397
xref: UnificationXref14398
left: Complex708
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1065
right: Complex709

Trimming of the first mannose on the A branch
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1366
EC number: 3.2.1.24
xref: UnificationXref14391
xref: UnificationXref14392
left: Complex705
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1065
right: Complex708

phospho-p-S724-ERN1
type: Protein
entity reference: Q93VJ2
data source: Provenance1
xref: UnificationXref14797
feature: ModificationFeature376
feature: FragmentFeature4364
cellular location: GO:0005789
comment: Reactome DB_ID: 4188964

Re-addition of a glucose on the alpha 1,3 branch
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1368
xref: UnificationXref14416
xref: UnificationXref14415
left: SmallMolecule1069
left: Complex705
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex710
right: SmallMolecule1070

Binding of calnexin/calreticulin to the unfolded protein
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1363
xref: UnificationXref14362
xref: UnificationXref14363
left: PhysicalEntity281
left: Complex702
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex703

Trimming of the first glucose by glucosidase I
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1362
EC number: 3.2.1.106
xref: UnificationXref14342
xref: UnificationXref14341
left: Complex700
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1060
right: Complex701

Trimming of the terminal mannose on the C branch
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1365
EC number: 3.2.1.24
xref: UnificationXref14386
xref: UnificationXref14385
left: Complex705
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1065
right: Complex707

Trimming of the terminal mannose on the B branch
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1364
EC number: 3.2.1.24
xref: UnificationXref14380
xref: UnificationXref14379
left: Complex705
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex706
right: SmallMolecule1065

phospho-p-S724-ERN1
type: Protein
entity reference: Q56WN0
data source: Provenance1
xref: UnificationXref14796
feature: ModificationFeature375
feature: FragmentFeature4363
cellular location: GO:0005789
comment: Reactome DB_ID: 4188962

phospho-p-S724-ERN1
type: Protein
entity reference: Q9FIN6
data source: Provenance1
xref: UnificationXref14795
feature: FragmentFeature4362
feature: ModificationFeature374
cellular location: GO:0005789
comment: Reactome DB_ID: 4188960

Homologues of p-S724-ERN1
type: Protein
data source: Provenance1
member physical entity: phospho-p-S724-ERN1
xref: UnificationXref14804
cellular location: GO:0005789
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4188977

Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1375
EC number: 3.2.1.113
xref: UnificationXref14479
xref: UnificationXref14478
participant stoichiometry: Stoichiometry1958
left: SmallMolecule1081
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1076
right: SmallMolecule1075

phospho-p-S724-ERN1
type: Protein
entity reference: Q9C5S2
data source: Provenance1
xref: UnificationXref14794
feature: FragmentFeature4361
feature: ModificationFeature373
cellular location: GO:0005789
comment: Reactome DB_ID: 4188958

Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1374
EC number: 3.2.1.113
xref: UnificationXref14473
xref: UnificationXref14474
participant stoichiometry: Stoichiometry1957
left: SmallMolecule1077
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1076
right: SmallMolecule1075

Q8RX75
type: Protein
entity reference: Q8RX75
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: IRE1
xref: UnificationXref14787
feature: FragmentFeature4359
cellular location: GO:0005789
comment: Reactome DB_ID: 4188950
display name: ERN1

Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1373
EC number: 3.2.1.113
xref: UnificationXref14463
xref: UnificationXref14464
participant stoichiometry: Stoichiometry1956
left: SmallMolecule1074
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1076
right: SmallMolecule1075

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SF12
data source: Provenance1
name: Q9SF12
name: IRE1
xref: UnificationXref14789
feature: FragmentFeature4360
cellular location: GO:0005789
comment: Reactome DB_ID: 4188954
display name: ERN1

Glycoproteins with major folding defects are sent to degradation by EDEMs
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1369
xref: UnificationXref14436
xref: UnificationXref14437
left: Complex708
left: Complex709
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex711
right: Complex712

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q94IG5
data source: Provenance1
name: IRE1
name: Q94IG5
xref: UnificationXref14783
feature: FragmentFeature4357
cellular location: GO:0005789
comment: Reactome DB_ID: 4188946
display name: ERN1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4KH41
data source: Provenance1
name: IRE1
name: F4KH41
xref: UnificationXref14785
feature: FragmentFeature4358
cellular location: GO:0005789
comment: Reactome DB_ID: 4188948
display name: ERN1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4KH40
data source: Provenance1
name: F4KH40
name: IRE1
xref: UnificationXref14779
feature: FragmentFeature4355
cellular location: GO:0005789
comment: Reactome DB_ID: 4188942
display name: ERN1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WPT1
data source: Provenance1
name: IRE1
name: Q0WPT1
xref: UnificationXref14781
feature: FragmentFeature4356
cellular location: GO:0005789
comment: Reactome DB_ID: 4188944
display name: ERN1

TIMM9:TIMM10 Binds Hydrophobic Proteins
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1389
xref: UnificationXref14599
xref: UnificationXref14598
left: Complex717
left: Proteins Chaperoned by TIMM9:TIMM10
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex718

http://identifiers.org/pubmed/23604073
type: PublicationXref
id: 23604073
author: Ablasser, A
author: Hopfner, KP
author: Deimling, Tobias
author: Hornung, V
author: Cavlar, Taner
db: Pubmed
title: Species-specific detection of the antiviral small-molecule compound CMA by STING
source: EMBO J. 32:1440-50
year: 2013

MIA40:ERV1 (CHCHD4:GFER) Catalyzes Formation of Disulfide Bonds
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1388
xref: UnificationXref14592
xref: UnificationXref14591
left: PhysicalEntity288
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity289

Addition of a GlcNAc on the alpha 1,4 branch by MGAT2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1382
EC number: 2.4.1.143
xref: UnificationXref14545
xref: UnificationXref14544
left: SmallMolecule1085
left: SmallMolecule84
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1087

Trimming of mannoses on the alpha1,6 arm by MAN2A1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1381
EC number: 3.2.1.114
xref: UnificationXref14537
xref: UnificationXref14538
participant stoichiometry: Stoichiometry1959
left: SmallMolecule1082
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1085
right: SmallMolecule1075

Addition of a bifurcating GlcNAc to the N-glycan by MGAT3
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1379
EC number: 2.4.1.144
xref: UnificationXref14518
xref: UnificationXref14517
left: SmallMolecule84
left: SmallMolecule1084
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity287

Addition of GlcNAc to the glycan on the A arm
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1377
EC number: 2.4.1.101
xref: UnificationXref14489
xref: UnificationXref14490
left: SmallMolecule1076
left: SmallMolecule84
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1082
right: SmallMolecule1083

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q93VJ2
data source: Provenance1
name: IRE1
name: Q93VJ2
xref: UnificationXref14777
feature: FragmentFeature4354
cellular location: GO:0005789
comment: Reactome DB_ID: 4188940
display name: ERN1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q56WN0
data source: Provenance1
name: IRE1
name: Q56WN0
xref: UnificationXref14775
feature: FragmentFeature4353
cellular location: GO:0005789
comment: Reactome DB_ID: 4188938
display name: ERN1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FIN6
data source: Provenance1
name: IRE1
name: Q9FIN6
xref: UnificationXref14773
feature: FragmentFeature4352
cellular location: GO:0005789
comment: Reactome DB_ID: 4188936
display name: ERN1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LC68
data source: Provenance1
name: TSYL2_HUMAN
name: Testis-specific Y-encoded-like protein 2
name: Q8LC68
xref: UnificationXref14939
feature: FragmentFeature4415
cellular location: GO:0005654
comment: Reactome DB_ID: 4197185
display name: TSPYL2

Formation of glucosamine 6-phosphate from fructose 6-phosphate and glutamine
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1335
EC number: 2.6.1.16
xref: UnificationXref14066
xref: UnificationXref14065
left: SmallMolecule15
left: SmallMolecule490
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1035
right: SmallMolecule43

Acetylation of glucosamine 6-phosphate to GlcNAc6P
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1336
EC number: 2.3.1.4
xref: UnificationXref14073
xref: UnificationXref14074
left: SmallMolecule1035
left: SmallMolecule90
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule92
right: SmallMolecule1036

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9CA59
data source: Provenance1
name: Q9CA59
name: TSYL2_HUMAN
name: Testis-specific Y-encoded-like protein 2
xref: UnificationXref14943
feature: FragmentFeature4417
cellular location: GO:0005654
comment: Reactome DB_ID: 4197189
display name: TSPYL2

Isomerization of GlcNAc6P to GlcNAc1P
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1337
EC number: 5.4.2.3
xref: UnificationXref14080
xref: UnificationXref14081
left: SmallMolecule1036
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1037

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9M9V0
data source: Provenance1
name: Q9M9V0
name: TSYL2_HUMAN
name: Testis-specific Y-encoded-like protein 2
xref: UnificationXref14941
feature: FragmentFeature4416
cellular location: GO:0005654
comment: Reactome DB_ID: 4197187
display name: TSPYL2

GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1338
EC number: 2.7.7.23
xref: UnificationXref14096
xref: UnificationXref14095
left: SmallMolecule51
left: SmallMolecule1037
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1017

Homologues of WIPI1
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14953
cellular location: GO:0000139
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4197358

Fructose 6-phosphate isomerizes to Mannose 6-phosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1340
EC number: 5.3.1.8
xref: UnificationXref14121
xref: UnificationXref14122
left: SmallMolecule15
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1038

Q8GXV1
type: Protein
entity reference: Q8GXV1
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: TSYL2_HUMAN
name: Testis-specific Y-encoded-like protein 2
xref: UnificationXref14945
feature: FragmentFeature4418
cellular location: GO:0005654
comment: Reactome DB_ID: 4197191
display name: TSPYL2

Mannose 6-phosphate isomerizes to Mannose 1-phosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1341
EC number: 5.4.2.8
xref: UnificationXref14130
xref: UnificationXref14131
left: SmallMolecule1038
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1039

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8H1Q8
data source: Provenance1
name: WIPI1_HUMAN
name: Q8H1Q8
name: WD repeat domain phosphoinositide-interacting protein 1
xref: UnificationXref14952
feature: FragmentFeature4420
cellular location: GO:0000139
comment: Reactome DB_ID: 4197357
display name: WIPI1

Mannose-1-phosphate converted to GDP-Mannose
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1342
EC number: 2.7.7.13
xref: UnificationXref14161
xref: UnificationXref14160
left: SmallMolecule1039
left: SmallMolecule460
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1040

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:F4JQB6
data source: Provenance1
name: F4JQB6
name: WIPI1_HUMAN
name: WD repeat domain phosphoinositide-interacting protein 1
xref: UnificationXref14950
feature: FragmentFeature4419
cellular location: GO:0000139
comment: Reactome DB_ID: 4197355
display name: WIPI1

Synthesis of dolichyl-phosphate-glucose
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1344
EC number: 2.4.1.117
xref: UnificationXref14173
xref: UnificationXref14172
left: SmallMolecule52
left: SmallMolecule1033
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1041

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q94BQ9
data source: Provenance1
name: Protein YIF1A
name: YIF1A(1-293)
name: YIF1A_HUMAN
name: Q94BQ9
xref: UnificationXref14957
feature: FragmentFeature4421
cellular location: GO:0005789
comment: Reactome DB_ID: 4197304
display name: YIF1A

Homologues of YIF1A(1-293)
type: Protein
data source: Provenance1
member physical entity: Q0WT16
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14966
cellular location: GO:0005789
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4197315

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q7XA88
data source: Provenance1
name: Q7XA88
name: Protein YIF1A
name: YIF1A(1-293)
name: YIF1A_HUMAN
xref: UnificationXref14959
feature: FragmentFeature4422
cellular location: GO:0005789
comment: Reactome DB_ID: 4197308
display name: YIF1A

Dephosphorylation of dolichyl diphosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1333
EC number: 3.6.1.43
xref: UnificationXref14054
xref: UnificationXref14055
left: SmallMolecule1034
left: SmallMolecule48
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1033
right: SmallMolecule31

Transferrin endocytosis and recycling
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction1089
evidence: Evidence1740
xref: UnificationXref18829
xref: UnificationXref18830
xref: RelationshipXref1434
pathway order: PathwayStep1709
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Phosphorylation of dolichol
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1332
EC number: 2.7.1.108
xref: UnificationXref14044
xref: UnificationXref14045
left: SmallMolecule1032
left: SmallMolecule302
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule578
right: SmallMolecule1033

BiochemicalReaction848
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1329
EC number: 2.7.8
xref: UnificationXref14028
xref: UnificationXref14029
left: SmallMolecule1030
display name: (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1031

E3 ubiquitin-protein ligase synoviolin
type: Protein
entity reference: B3H675
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: B3H675
name: SYVN1_HUMAN
name: SYVN1(1-617)
xref: UnificationXref14917
feature: FragmentFeature4408
cellular location: GO:0005789
comment: Reactome DB_ID: 4197256
display name: SYVN1

Addition of a fourth and fifth mannose to the N-glycan precursor by ALG11
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1352
xref: UnificationXref14235
xref: UnificationXref14234
participant stoichiometry: Stoichiometry1927
participant stoichiometry: Stoichiometry1928
left: SmallMolecule1046
left: SmallMolecule1040
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule486
right: SmallMolecule1047

E3 ubiquitin-protein ligase synoviolin
type: Protein
entity reference: Q6NPT7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q6NPT7
name: SYVN1_HUMAN
name: SYVN1(1-617)
xref: UnificationXref14915
feature: FragmentFeature4407
cellular location: GO:0005789
comment: Reactome DB_ID: 4197254
display name: SYVN1

Flipping of the N-glycan precursor to inside the ER
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1353
xref: UnificationXref14242
xref: UnificationXref14241
left: SmallMolecule1047
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1048

Addition of a second mannose to the N-glycan precursor by ALG2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1350
xref: UnificationXref14218
xref: UnificationXref14217
left: SmallMolecule1044
left: SmallMolecule1040
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1045
right: SmallMolecule486

Addition of a third mannose to the N-glycan precursor by ALG2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1351
xref: UnificationXref14223
xref: UnificationXref14222
left: SmallMolecule1045
left: SmallMolecule1040
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1046
right: SmallMolecule486

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LUF6
data source: Provenance1
name: Prolactin regulatory element-binding protein
name: Sec12
name: Q9LUF6
name: PREB_HUMAN
xref: UnificationXref14926
feature: FragmentFeature4411
cellular location: GO:0005789
comment: Reactome DB_ID: 4197238
display name: PREB

Addition of the eighth mannose to the N-glycan precursor by ALG12, inside the ER lumen
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1356
xref: UnificationXref14285
xref: UnificationXref14286
left: SmallMolecule1049
left: SmallMolecule1052
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1050
right: SmallMolecule1053

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q39221
data source: Provenance1
name: Q39221
name: Prolactin regulatory element-binding protein
name: Sec12
name: PREB_HUMAN
xref: UnificationXref14924
feature: FragmentFeature4410
cellular location: GO:0005789
comment: Reactome DB_ID: 4197236
display name: PREB

Addition of the last mannose to the N-glycan precursor by ALG3, inside the ER lumen.
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1357
xref: UnificationXref14291
xref: UnificationXref14290
left: SmallMolecule1049
left: SmallMolecule1053
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1054
right: SmallMolecule1050

Q9FGP3
type: Protein
entity reference: Q9FGP3
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Prolactin regulatory element-binding protein
name: Sec12
name: PREB_HUMAN
xref: UnificationXref14922
feature: FragmentFeature4409
cellular location: GO:0005789
comment: Reactome DB_ID: 4197232
display name: PREB

Addition of the sixth mannose to the N-glycan precursor by ALG3.
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1354
xref: UnificationXref14261
xref: UnificationXref14260
left: SmallMolecule1049
left: SmallMolecule1048
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1051
right: SmallMolecule1050

Homologues of PREB
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q9FGP3
xref: UnificationXref14929
cellular location: GO:0005789
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4197243

Addition of the seventh mannose to the N-glycan precursor by ALG9, inside the ER lumen
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1355
xref: UnificationXref14268
xref: UnificationXref14267
left: SmallMolecule1051
left: SmallMolecule1049
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1050
right: SmallMolecule1052

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4HVQ1
data source: Provenance1
name: F4HVQ1
name: TSYL2_HUMAN
name: Testis-specific Y-encoded-like protein 2
xref: UnificationXref14937
feature: FragmentFeature4414
cellular location: GO:0005654
comment: Reactome DB_ID: 4197181
display name: TSPYL2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: A8MSD9
data source: Provenance1
name: A8MSD9
name: TSYL2_HUMAN
name: Testis-specific Y-encoded-like protein 2
xref: UnificationXref14935
feature: FragmentFeature4413
cellular location: GO:0005654
comment: Reactome DB_ID: 4197179
display name: TSPYL2

Homologues of TSPYL2
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q8GXV1
xref: UnificationXref14946
cellular location: GO:0005654
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4197192

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GYE0
data source: Provenance1
name: Prolactin regulatory element-binding protein
name: Sec12
name: Q8GYE0
name: PREB_HUMAN
xref: UnificationXref14928
feature: FragmentFeature4412
cellular location: GO:0005789
comment: Reactome DB_ID: 4197242
display name: PREB

Addition of the second N-acetyl-glucosamine to the N-glycan precursor
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1348
EC number: 2.4.1.141
xref: UnificationXref14196
xref: UnificationXref14195
left: SmallMolecule1017
left: SmallMolecule1042
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule579
right: SmallMolecule1043

Addition of the first mannose to the N-glycan precursor by ALG13/14
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1349
EC number: 2.4.1.142
xref: UnificationXref14205
xref: UnificationXref14206
left: SmallMolecule1043
left: SmallMolecule1040
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1044
right: SmallMolecule486

http://identifiers.org/pubmed/19006241
type: PublicationXref
id: 19006241
author: Häberle, J
author: Höhne, W
author: Engel, K
db: Pubmed
title: Mutations and polymorphisms in the human argininosuccinate synthetase (ASS1) gene
source: Hum Mutat 30:300-7
year: 2009

UniProt:F4JQU2
type: ProteinReference
xref: UnificationXref9049
organism: Arabidopsis thaliana

UniProt:F4JQU1
type: ProteinReference
xref: UnificationXref9057
organism: Arabidopsis thaliana

Addition of N-acetyl-D-glucosamine to Dolichyl phosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1347
EC number: 2.7.8.15
xref: UnificationXref14189
xref: UnificationXref14188
left: SmallMolecule1017
left: SmallMolecule1033
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule86
right: SmallMolecule1042

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04375
data source: Provenance1
name: 2A5B_HUMAN
name: PPP2R5B
name: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
xref: UnificationXref14896
feature: FragmentFeature4400
cellular location: GO:0005829
comment: Reactome DB_ID: 4189043
display name: O04375

Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1303
xref: UnificationXref13753
xref: UnificationXref13754
xref: RelationshipXref1134
left: Complex679
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex681
right: PhysicalEntity270

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LF36
data source: Provenance1
name: 2A5B_HUMAN
name: PPP2R5B
name: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
xref: UnificationXref14895
feature: FragmentFeature4399
cellular location: GO:0005829
comment: Reactome DB_ID: 4189042
display name: Q8LF36

Actin/tubulin:prefoldin complex associates with CCT/TriC
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1306
xref: UnificationXref13823
xref: UnificationXref13822
left: Complex682
left: Complex684
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex685
right: Complex683

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZQY6
data source: Provenance1
name: 2A5B_HUMAN
name: PPP2R5B
name: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
xref: UnificationXref14898
feature: FragmentFeature4402
cellular location: GO:0005829
comment: Reactome DB_ID: 4189045
display name: Q9ZQY6

ADP is exchanged for ATP in the (ADP:CCT/TriC):tubulin complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1308
xref: UnificationXref13829
xref: UnificationXref13830
participant stoichiometry: Stoichiometry1880
participant stoichiometry: Stoichiometry1893
left: SmallMolecule11
left: Complex686
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule14
right: Complex687

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SV41
data source: Provenance1
name: 2A5B_HUMAN
name: PPP2R5B
name: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
xref: UnificationXref14897
feature: FragmentFeature4401
cellular location: GO:0005829
comment: Reactome DB_ID: 4189044
display name: Q9SV41

Exchange of ADP for ATP in CCT/TriC:actin complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1310
xref: UnificationXref13838
xref: UnificationXref13837
participant stoichiometry: Stoichiometry1897
participant stoichiometry: Stoichiometry1896
left: SmallMolecule11
left: Complex688
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex689
right: SmallMolecule14

Formation of eEF1B complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1299
xref: UnificationXref13723
xref: UnificationXref13724
left: Protein4852
left: Protein4849
left: Protein4857
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex675

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q93YV6
data source: Provenance1
name: 2A5B_HUMAN
name: PPP2R5B
name: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
xref: UnificationXref14894
feature: FragmentFeature4398
cellular location: GO:0005829
comment: Reactome DB_ID: 4189041
display name: Q93YV6

GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1301
xref: UnificationXref13742
xref: RelationshipXref1134
xref: UnificationXref13741
left: Protein4865
left: Complex677
left: Complex672
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex678

GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1302
xref: UnificationXref13745
xref: UnificationXref13746
xref: RelationshipXref1134
left: Complex678
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex679
right: SmallMolecule31

Q27GM7
type: Protein
entity reference: Q27GM7
data source: Provenance1
name: E3 ubiquitin-protein ligase synoviolin
name: Note: the coordinates are copied over from Homo sapiens.
name: SYVN1_HUMAN
name: SYVN1(1-617)
xref: UnificationXref14913
feature: FragmentFeature4406
cellular location: GO:0005789
comment: Reactome DB_ID: 4197252
display name: SYVN1

Extension of Telomeres
type: Pathway
data source: Provenance1
pathway component: REACT 103769.9
pathway component: Telomere Extension By Telomerase
evidence: Evidence1649
xref: UnificationXref17715
xref: UnificationXref17714
pathway order: PathwayStep1605
pathway order: PathwayStep1622
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8RW96
data source: Provenance1
name: 2A5B_HUMAN
name: PPP2R5B
name: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
xref: UnificationXref14900
feature: FragmentFeature4404
cellular location: GO:0005829
comment: Reactome DB_ID: 4189047
display name: Q8RW96

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LU89
data source: Provenance1
name: 2A5B_HUMAN
name: PPP2R5B
name: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
xref: UnificationXref14899
feature: FragmentFeature4403
cellular location: GO:0005829
comment: Reactome DB_ID: 4189046
display name: Q9LU89

E3 ubiquitin-protein ligase synoviolin
type: Protein
entity reference: Q9LW77
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q9LW77
name: SYVN1_HUMAN
name: SYVN1(1-617)
xref: UnificationXref14911
feature: FragmentFeature4405
cellular location: GO:0005789
comment: Reactome DB_ID: 4197248
display name: SYVN1

Homologues of SYVN1(1-617)
type: Protein
data source: Provenance1
member physical entity: E3 ubiquitin-protein ligase synoviolin
member physical entity: Q27GM7
xref: UnificationXref14918
cellular location: GO:0005789
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4197257

Translocation of ribosome by 3 bases in the 3' direction
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1295
xref: UnificationXref13695
xref: UnificationXref13694
participant stoichiometry: Stoichiometry1838
left: Complex673
left: Complex668
left: Complex672
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex671
right: Complex674
right: Complex672
right: SmallMolecule31

Peptide transfer from P-site tRNA to the A-site tRNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1294
EC number: 2.3.2.12
xref: UnificationXref13671
xref: UnificationXref13672
left: Complex670
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex672

Regeneration of eEF1A:GTP by eEF1B activity
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1298
xref: UnificationXref13722
xref: UnificationXref13721
left: Complex671
left: Complex675
left: SmallMolecule460
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex676
right: Complex667

GTP-binding activates eEF2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1296
xref: UnificationXref13696
xref: UnificationXref13697
left: Protein4839
left: SmallMolecule460
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex673

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LJR8
data source: Provenance1
name: ERD23_HUMAN
name: Q9LJR8
name: ER lumen protein retaining receptor 3
xref: UnificationXref14882
feature: FragmentFeature4392
cellular location: GO:0005789
comment: Reactome DB_ID: 4197279
display name: KDELR3

BiochemicalReaction846
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1327
xref: UnificationXref14005
xref: UnificationXref14004
left: SmallMolecule1027
left: SmallMolecule1026
display name: mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1028
right: SmallMolecule1029

Homologues of KDELR3
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14889
cellular location: GO:0005789
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4197288

BiochemicalReaction847
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1328
EC number: 2.7.8
xref: UnificationXref14021
xref: UnificationXref14020
left: SmallMolecule1023
left: SmallMolecule1029
display name: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1025
right: SmallMolecule1030

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O23509
data source: Provenance1
name: HYOU1_HUMAN
name: O23509
name: Hypoxia up-regulated protein 1
xref: UnificationXref14877
feature: FragmentFeature4391
cellular location: GO:0005788
comment: Reactome DB_ID: 4197218
display name: HYOU1

mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1325
EC number: 2.7.8
xref: UnificationXref13977
xref: UnificationXref13978
left: SmallMolecule1024
left: SmallMolecule1023
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1025
right: PhysicalEntity278

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q949M5
data source: Provenance1
name: HYOU1_HUMAN
name: Hypoxia up-regulated protein 1
name: Q949M5
xref: UnificationXref14875
feature: FragmentFeature4390
cellular location: GO:0005788
comment: Reactome DB_ID: 4197216
display name: HYOU1

(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1326
xref: UnificationXref13995
xref: UnificationXref13994
left: PhysicalEntity278
left: SmallMolecule1026
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1028
right: SmallMolecule1027

N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1323
EC number: 3.5.1.89
xref: UnificationXref13952
xref: UnificationXref13953
left: SmallMolecule1018
left: SmallMolecule48
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule797
right: SmallMolecule1019

glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1324
xref: UnificationXref13964
xref: UnificationXref13963
left: SmallMolecule1020
left: SmallMolecule1019
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1021
right: SmallMolecule1022

EIF5A(Dhp) + O2 => EIF5A(Hyp)
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1319
EC number: 1.14.99.29
xref: UnificationXref13897
xref: UnificationXref13898
left: SmallMolecule240
left: PhysicalEntity275
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity276

phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1322
xref: UnificationXref13939
xref: UnificationXref13938
left: SmallMolecule1017
left: SmallMolecule1016
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1018
right: SmallMolecule579

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04376
data source: Provenance1
name: 2A5B_HUMAN
name: PPP2R5B
name: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
xref: UnificationXref14893
feature: FragmentFeature4397
cellular location: GO:0005829
comment: Reactome DB_ID: 4189040
display name: O04376

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LVE2
data source: Provenance1
name: 2A5B_HUMAN
name: PPP2R5B
name: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
xref: UnificationXref14892
feature: FragmentFeature4396
cellular location: GO:0005829
comment: Reactome DB_ID: 4189039
display name: Q9LVE2

Homologues of PPP2R5B
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14901
cellular location: GO:0005829
comment: Reactome DB_ID: 4189048
comment: Converted from EntitySet in Reactome

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: P35402
data source: Provenance1
name: ERD23_HUMAN
name: ER lumen protein retaining receptor 3
name: P35402
xref: UnificationXref14888
feature: FragmentFeature4395
cellular location: GO:0005789
comment: Reactome DB_ID: 4197287
display name: KDELR3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LD09
data source: Provenance1
name: ERD23_HUMAN
name: ER lumen protein retaining receptor 3
name: Q8LD09
xref: UnificationXref14886
feature: FragmentFeature4394
cellular location: GO:0005789
comment: Reactome DB_ID: 4197283
display name: KDELR3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8VWI1
data source: Provenance1
name: ERD23_HUMAN
name: ER lumen protein retaining receptor 3
name: Q8VWI1
xref: UnificationXref14884
feature: FragmentFeature4393
cellular location: GO:0005789
comment: Reactome DB_ID: 4197281
display name: KDELR3

EIF5A(Dhp) + 1,3-diaminopropane <=> EIF5A + spermidine
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1318
EC number: 2.5.1.46
xref: UnificationXref13883
xref: UnificationXref13882
left: SmallMolecule37
left: PhysicalEntity275
left: SmallMolecule1015
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule34
right: SmallMolecule733
right: PhysicalEntity274

EIF5A + spermidine <=> EIF5A(Dhp) + 1,3-diaminopropane
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1317
EC number: 2.5.1.46
xref: UnificationXref13881
xref: UnificationXref13880
left: SmallMolecule34
left: SmallMolecule733
left: PhysicalEntity274
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule37
right: PhysicalEntity275
right: SmallMolecule36
right: SmallMolecule1015

Association of CCT/TriC with sphingosine kinase 1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1313
xref: UnificationXref13844
xref: UnificationXref13845
left: Protein1131
left: Complex684
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex691

http://identifiers.org/pubmed/12205100
type: PublicationXref
id: 12205100
author: Van Komen, S
author: Sigurdsson, S
author: Petukhova, G
author: Sung, P
db: Pubmed
title: Homologous DNA pairing by human recombination factors Rad51 and Rad54
source: J Biol Chem 277:42790-4
year: 2002

http://identifiers.org/pubmed/4218100
type: PublicationXref
id: 4218100
author: Matalon, R
author: Brandt, IK
author: Dorfman, A
author: Justice, P
author: Arbogast, B
db: Pubmed
title: Morquio's syndrome: deficiency of a chondroitin sulfate N-acetylhexosamine sulfate sulfatase
source: Biochem Biophys Res Commun 61:759-65
year: 1974

Q9LX74
type: Protein
entity reference: Q9LX74
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: EXOS5_HUMAN
name: Exosome complex exonuclease RRP46
xref: UnificationXref14994
feature: FragmentFeature4430
cellular location: GO:0005829
comment: Reactome DB_ID: 4190540
display name: EXOSC5

Homologues of EXOSC6
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q8GWJ0
xref: UnificationXref14999
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4190524

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4J8C0
data source: Provenance1
name: F4J8C0
name: Protein YIF1A
name: YIF1A(1-293)
name: YIF1A_HUMAN
xref: UnificationXref14961
feature: FragmentFeature4423
cellular location: GO:0005789
comment: Reactome DB_ID: 4197310
display name: YIF1A

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9M1B7
data source: Provenance1
name: Q9M1B7
name: Protein YIF1A
name: YIF1A(1-293)
name: YIF1A_HUMAN
xref: UnificationXref14963
feature: FragmentFeature4424
cellular location: GO:0005789
comment: Reactome DB_ID: 4197312
display name: YIF1A

Q0WT16
type: Protein
entity reference: Q0WT16
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Protein YIF1A
name: YIF1A(1-293)
name: YIF1A_HUMAN
xref: UnificationXref14965
feature: FragmentFeature4425
cellular location: GO:0005789
comment: Reactome DB_ID: 4197314
display name: YIF1A

http://identifiers.org/pubmed/18403674
type: PublicationXref
id: 18403674
author: Steele, C
author: Mossman, BT
author: Dostert, C
author: Tschopp, J
author: Van Bruggen, R
author: Pétrilli, V
db: Pubmed
title: Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
source: Science 320:674-7
year: 2008

Q9LYW9
type: Protein
entity reference: Q9LYW9
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: p58IPK
xref: UnificationXref14970
feature: FragmentFeature4426
cellular location: GO:0005788
comment: Reactome DB_ID: 4197333
display name: DNAJC3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZUI4
data source: Provenance1
name: Exosome complex exonuclease RRP43
name: EXOS8_HUMAN
name: Q9ZUI4
xref: UnificationXref14986
feature: FragmentFeature4427
cellular location: GO:0005829
comment: Reactome DB_ID: 4190536
display name: EXOSC8

Homologues of EXOSC7
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14992
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4190532

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SFD4
data source: Provenance1
name: EXOS7_HUMAN
name: Exosome complex exonuclease RRP42
name: Q9SFD4
xref: UnificationXref14989
feature: FragmentFeature4428
cellular location: GO:0005829
comment: Reactome DB_ID: 4190529
display name: EXOSC7

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FPI0
data source: Provenance1
name: Q9FPI0
name: EXOS7_HUMAN
name: Exosome complex exonuclease RRP42
xref: UnificationXref14991
feature: FragmentFeature4429
cellular location: GO:0005829
comment: Reactome DB_ID: 4190531
display name: EXOSC7

UniProt:Q94LA4
type: ProteinReference
xref: UnificationXref6637
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/20930137
type: PublicationXref
id: 20930137
author: Kull, FJ
author: Endow, SA
author: Liu, H
db: Pubmed
title: Kinesins at a glance
source: J Cell Sci 123:3420-4
year: 2010

Amine compound SLC transporters
type: Pathway
data source: Provenance1
pathway component: REACT 154020.3
pathway component: BiochemicalReaction192
evidence: Evidence1158
xref: UnificationXref12479
xref: UnificationXref12478
pathway order: PathwayStep1140
pathway order: PathwayStep263
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Stoichiometry2480
type: Stoichiometry
physical entity: Complex846
stoichiometric coefficient: 1.0

Stoichiometry2481
type: Stoichiometry
physical entity: Protein3898
stoichiometric coefficient: 1.0

Stoichiometry2482
type: Stoichiometry
physical entity: PhysicalEntity227
stoichiometric coefficient: 1.0

Stoichiometry2483
type: Stoichiometry
physical entity: Protein4232
stoichiometric coefficient: 1.0

Stoichiometry2484
type: Stoichiometry
physical entity: Protein6500
stoichiometric coefficient: 1.0

Stoichiometry2485
type: Stoichiometry
physical entity: Complex848
stoichiometric coefficient: 1.0

Stoichiometry2486
type: Stoichiometry
physical entity: Complex848
stoichiometric coefficient: 1.0

Stoichiometry2487
type: Stoichiometry
physical entity: Protein6501
stoichiometric coefficient: 1.0

Stoichiometry2488
type: Stoichiometry
physical entity: SmallMolecule534
stoichiometric coefficient: 4.0

http://identifiers.org/pubmed/9083101
type: PublicationXref
id: 9083101
author: Hosaka, K
author: Nikawa, J
author: Nakashima, A
db: Pubmed
title: Cloning of a human cDNA for CTP-phosphoethanolamine cytidylyltransferase by complementation in vivo of a yeast mutant
source: J Biol Chem 272:9567-72
year: 1997

Stoichiometry2489
type: Stoichiometry
physical entity: SmallMolecule921
stoichiometric coefficient: 4.0

UniProt:Q6EWX0
type: ProteinReference
xref: UnificationXref12031
organism: Arabidopsis thaliana

UniProt:Q6EWX1
type: ProteinReference
xref: UnificationXref12038
organism: Arabidopsis thaliana

Stoichiometry2471
type: Stoichiometry
physical entity: Protein6470
stoichiometric coefficient: 1.0

Stoichiometry2472
type: Stoichiometry
physical entity: PhysicalEntity383
stoichiometric coefficient: 1.0

Stoichiometry2470
type: Stoichiometry
physical entity: PhysicalEntity383
stoichiometric coefficient: 1.0

Stoichiometry2475
type: Stoichiometry
physical entity: Protein3409
stoichiometric coefficient: 4.0

Stoichiometry2476
type: Stoichiometry
physical entity: Protein6493
stoichiometric coefficient: 1.0

Stoichiometry2473
type: Stoichiometry
physical entity: PhysicalEntity385
stoichiometric coefficient: 2.0

Stoichiometry2474
type: Stoichiometry
physical entity: Protein3409
stoichiometric coefficient: 4.0

Stoichiometry2479
type: Stoichiometry
physical entity: Protein6499
stoichiometric coefficient: 1.0

Stoichiometry2477
type: Stoichiometry
physical entity: Protein3409
stoichiometric coefficient: 4.0

Stoichiometry2478
type: Stoichiometry
physical entity: PhysicalEntity386
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/8399223
type: PublicationXref
id: 8399223
author: Tanhauser, SM
author: Chen, X
author: Silverman, DN
author: Laipis, PJ
author: Kresge, AJ
author: Tu, C
db: Pubmed
title: Rate-equilibria relationships in intramolecular proton transfer in human carbonic anhydrase III
source: Biochemistry 32:10757-62
year: 1993

Stoichiometry2497
type: Stoichiometry
physical entity: Protein4258
stoichiometric coefficient: 1.0

Stoichiometry2498
type: Stoichiometry
physical entity: Complex852
stoichiometric coefficient: 1.0

Stoichiometry2495
type: Stoichiometry
physical entity: PhysicalEntity391
stoichiometric coefficient: 1.0

Stoichiometry2496
type: Stoichiometry
physical entity: PhysicalEntity225
stoichiometric coefficient: 1.0

Stoichiometry2493
type: Stoichiometry
physical entity: SmallMolecule534
stoichiometric coefficient: 3.0

Stoichiometry2494
type: Stoichiometry
physical entity: SmallMolecule921
stoichiometric coefficient: 3.0

http://identifiers.org/pubmed/17765544
type: PublicationXref
id: 17765544
author: Cote, Jean-Francois
author: Vuori, K
db: Pubmed
title: GEF what? Dock180 and related proteins help Rac to polarize cells in new ways
source: Trends Cell Biol 17:383-93
year: 2007

Stoichiometry2491
type: Stoichiometry
physical entity: PhysicalEntity388
stoichiometric coefficient: 1.0

Stoichiometry2492
type: Stoichiometry
physical entity: PhysicalEntity389
stoichiometric coefficient: 1.0

Stoichiometry2499
type: Stoichiometry
physical entity: Protein6507
stoichiometric coefficient: 1.0

Stoichiometry2490
type: Stoichiometry
physical entity: PhysicalEntity387
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/12151002
type: PublicationXref
id: 12151002
author: Paiement, J
author: Desjardins, M
author: Bergeron, JJ
author: Cameron, PH
author: Duclos, S
author: Chevet, E
author: Gagnon, E
author: Steele-Mortimer, O
author: Rondeau, C
db: Pubmed
title: Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages
source: Cell 110:119-31
year: 2002

UnificationXref1733
type: UnificationXref
id: 4199447
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199447

SequenceSite5608
type: SequenceSite
position status: EQUAL
sequence position: 5

UnificationXref1732
type: UnificationXref
id: REACT_30077
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_30077.10

SequenceSite5609
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1731
type: UnificationXref
id: 4199446
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199446

UnificationXref1730
type: UnificationXref
id: REACT_110966
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_110966.9

SequenceSite5600
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite5601
type: SequenceSite
position status: EQUAL
sequence position: 150

SequenceSite5602
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5603
type: SequenceSite
position status: EQUAL
sequence position: 127

SequenceSite5604
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5605
type: SequenceSite
position status: EQUAL
sequence position: 127

http://identifiers.org/pubmed/15838516
type: PublicationXref
id: 15838516
author: Cobrinik, D
db: Pubmed
title: Pocket proteins and cell cycle control
source: Oncogene 24:2796-809
year: 2005

SequenceSite5606
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5607
type: SequenceSite
position status: EQUAL
sequence position: 1174

Stoichiometry2447
type: Stoichiometry
physical entity: PhysicalEntity380
stoichiometric coefficient: 1.0

Stoichiometry2446
type: Stoichiometry
physical entity: Protein6459
stoichiometric coefficient: 1.0

Stoichiometry2445
type: Stoichiometry
physical entity: PhysicalEntity380
stoichiometric coefficient: 1.0

Stoichiometry2444
type: Stoichiometry
physical entity: Protein6448
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/9593664
type: PublicationXref
id: 9593664
author: Maehama, T
author: Dixon, JE
db: Pubmed
title: The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
source: J Biol Chem 273:13375-8
year: 1998

Stoichiometry2449
type: Stoichiometry
physical entity: Protein6437
stoichiometric coefficient: 1.0

Stoichiometry2448
type: Stoichiometry
physical entity: Protein6470
stoichiometric coefficient: 1.0

UnificationXref1729
type: UnificationXref
id: 4180930
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4180930

UnificationXref1727
type: UnificationXref
id: 4180927
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4180927

UnificationXref1728
type: UnificationXref
id: 4180928
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4180928

Stoichiometry2443
type: Stoichiometry
physical entity: PhysicalEntity380
stoichiometric coefficient: 1.0

UnificationXref1725
type: UnificationXref
id: REACT_5224
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5224.2

Stoichiometry2442
type: Stoichiometry
physical entity: Protein6437
stoichiometric coefficient: 1.0

UnificationXref1726
type: UnificationXref
id: O81027
db: UniProt

Stoichiometry2441
type: Stoichiometry
physical entity: PhysicalEntity380
stoichiometric coefficient: 1.0

UnificationXref1723
type: UnificationXref
id: CHEBI:15344
db: ChEBI

Stoichiometry2440
type: Stoichiometry
physical entity: Protein6436
stoichiometric coefficient: 1.0

UnificationXref1724
type: UnificationXref
id: 73909
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=73909

UnificationXref1720
type: UnificationXref
id: 4180695
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4180695

UnificationXref1722
type: UnificationXref
id: REACT_97386
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_97386.9

SequenceSite5619
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1721
type: UnificationXref
id: 4180697
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4180697

SequenceSite5613
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5614
type: SequenceSite
position status: EQUAL
sequence position: 58

SequenceSite5611
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5612
type: SequenceSite
position status: EQUAL
sequence position: 58

SequenceSite5617
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5618
type: SequenceSite
position status: EQUAL
sequence position: 67

SequenceSite5615
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5616
type: SequenceSite
position status: EQUAL
sequence position: 172

Stoichiometry2434
type: Stoichiometry
physical entity: Protein6427
stoichiometric coefficient: 1.0

Stoichiometry2433
type: Stoichiometry
physical entity: Complex820
stoichiometric coefficient: 1.0

Stoichiometry2436
type: Stoichiometry
physical entity: Complex820
stoichiometric coefficient: 1.0

Stoichiometry2435
type: Stoichiometry
physical entity: PhysicalEntity378
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/9153396
type: PublicationXref
id: 9153396
author: Vousden, KH
author: Kubbutat, MH
author: Jones, SN
db: Pubmed
title: Regulation of p53 stability by Mdm2.
source: Nature 387:299-303
year: 1997

Stoichiometry2438
type: Stoichiometry
physical entity: Protein6432
stoichiometric coefficient: 1.0

SequenceSite5610
type: SequenceSite
position status: EQUAL
sequence position: 1970

http://identifiers.org/pubmed/9153395
type: PublicationXref
id: 9153395
author: Haupt, Y
author: Maya, R
author: Oren, M
author: Kazaz, A
db: Pubmed
title: Mdm2 promotes the rapid degradation of p53.
source: Nature 387:296-9
year: 1997

Stoichiometry2437
type: Stoichiometry
physical entity: SmallMolecule460
stoichiometric coefficient: 1.0

Stoichiometry2439
type: Stoichiometry
physical entity: Complex823
stoichiometric coefficient: 1.0

UnificationXref1716
type: UnificationXref
id: CHEBI:15467
db: ChEBI

UnificationXref1717
type: UnificationXref
id: 73917
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=73917

UnificationXref1718
type: UnificationXref
id: REACT_3208
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3208.2

UnificationXref1719
type: UnificationXref
id: P54873
db: UniProt

Stoichiometry2430
type: Stoichiometry
physical entity: Protein6427
stoichiometric coefficient: 1.0

UnificationXref1712
type: UnificationXref
id: 73871
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=73871

UnificationXref1713
type: UnificationXref
id: REACT_2705
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2705.2

Stoichiometry2432
type: Stoichiometry
physical entity: Protein6428
stoichiometric coefficient: 1.0

UnificationXref1714
type: UnificationXref
id: 29374
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29374

Stoichiometry2431
type: Stoichiometry
physical entity: SmallMolecule924
stoichiometric coefficient: 1.0

UnificationXref1715
type: UnificationXref
id: REACT_3654
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3654.2

UnificationXref1751
type: UnificationXref
id: O23310
db: UniProt

UnificationXref1750
type: UnificationXref
id: 4196632
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196632

UnificationXref1755
type: UnificationXref
id: Q84W66
db: UniProt

UnificationXref1754
type: UnificationXref
id: 4196640
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196640

UnificationXref1753
type: UnificationXref
id: Q67XJ2
db: UniProt

UnificationXref1752
type: UnificationXref
id: 4196636
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196636

SequenceSite5626
type: SequenceSite
position status: EQUAL
sequence position: 961

SequenceSite5627
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5628
type: SequenceSite
position status: EQUAL
sequence position: 961

SequenceSite5629
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5622
type: SequenceSite
position status: EQUAL
sequence position: 961

SequenceSite5623
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5624
type: SequenceSite
position status: EQUAL
sequence position: 961

http://identifiers.org/pubmed/10413847
type: PublicationXref
id: 10413847
author: Bläker, M
author: de Weerth, A
author: von Schrenck, T
db: Pubmed
title: [Receptors for cholecystokinin and gastrin]
source: Z Gastroenterol 37:389-401
year: 1999

SequenceSite5625
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5621
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5620
type: SequenceSite
position status: EQUAL
sequence position: 67

Stoichiometry2469
type: Stoichiometry
physical entity: Protein6459
stoichiometric coefficient: 1.0

Stoichiometry2468
type: Stoichiometry
physical entity: PhysicalEntity383
stoichiometric coefficient: 1.0

Stoichiometry2467
type: Stoichiometry
physical entity: Protein6437
stoichiometric coefficient: 1.0

Stoichiometry2466
type: Stoichiometry
physical entity: PhysicalEntity382
stoichiometric coefficient: 1.0

Stoichiometry2465
type: Stoichiometry
physical entity: Protein6470
stoichiometric coefficient: 1.0

UnificationXref1747
type: UnificationXref
id: 4184395
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184395

Stoichiometry2464
type: Stoichiometry
physical entity: PhysicalEntity382
stoichiometric coefficient: 1.0

UnificationXref1748
type: UnificationXref
id: REACT_88257
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_88257.9

Stoichiometry2463
type: Stoichiometry
physical entity: Protein6459
stoichiometric coefficient: 1.0

UnificationXref1745
type: UnificationXref
id: Q9SS48
db: UniProt

Stoichiometry2462
type: Stoichiometry
physical entity: PhysicalEntity382
stoichiometric coefficient: 1.0

UnificationXref1746
type: UnificationXref
id: 4184393
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184393

Stoichiometry2461
type: Stoichiometry
physical entity: Protein6437
stoichiometric coefficient: 1.0

Stoichiometry2460
type: Stoichiometry
physical entity: PhysicalEntity383
stoichiometric coefficient: 1.0

UnificationXref1749
type: UnificationXref
id: Q9SIT9
db: UniProt

UnificationXref1740
type: UnificationXref
id: CHEBI:17877
db: ChEBI

UnificationXref1742
type: UnificationXref
id: REACT_3082
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3082.1

UnificationXref1741
type: UnificationXref
id: 31649
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=31649

UnificationXref1744
type: UnificationXref
id: REACT_18250
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_18250.2

UnificationXref1743
type: UnificationXref
id: 188451
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=188451

SequenceSite5639
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5637
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5638
type: SequenceSite
position status: EQUAL
sequence position: 961

SequenceSite5635
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5636
type: SequenceSite
position status: EQUAL
sequence position: 961

SequenceSite5633
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5634
type: SequenceSite
position status: EQUAL
sequence position: 961

SequenceSite5632
type: SequenceSite
position status: EQUAL
sequence position: 961

Stoichiometry2459
type: Stoichiometry
physical entity: Protein6448
stoichiometric coefficient: 1.0

SequenceSite5631
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5630
type: SequenceSite
position status: EQUAL
sequence position: 961

Stoichiometry2456
type: Stoichiometry
physical entity: Protein6470
stoichiometric coefficient: 1.0

Stoichiometry2455
type: Stoichiometry
physical entity: PhysicalEntity381
stoichiometric coefficient: 1.0

Stoichiometry2458
type: Stoichiometry
physical entity: PhysicalEntity382
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/7962183
type: PublicationXref
id: 7962183
author: Tang, CJ
author: Chao, YJ
author: Tang, TK
author: Wu, CW
db: Pubmed
title: Nuclear mitotic apparatus protein (NuMA): spindle association, nuclear targeting and differential subcellular localization of various NuMA isoforms
source: J Cell Sci 107:1389-402
year: 1994

Stoichiometry2457
type: Stoichiometry
physical entity: Protein6448
stoichiometric coefficient: 1.0

Stoichiometry2452
type: Stoichiometry
physical entity: Protein6448
stoichiometric coefficient: 1.0

UnificationXref1734
type: UnificationXref
id: REACT_78769
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_78769.9

Stoichiometry2451
type: Stoichiometry
physical entity: PhysicalEntity381
stoichiometric coefficient: 1.0

UnificationXref1735
type: UnificationXref
id: CHEBI:16238
db: ChEBI

Stoichiometry2454
type: Stoichiometry
physical entity: Protein6459
stoichiometric coefficient: 1.0

UnificationXref1736
type: UnificationXref
id: 113596
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113596

Stoichiometry2453
type: Stoichiometry
physical entity: PhysicalEntity381
stoichiometric coefficient: 1.0

UnificationXref1737
type: UnificationXref
id: REACT_5229
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5229.1

UnificationXref1738
type: UnificationXref
id: 188458
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=188458

UnificationXref1739
type: UnificationXref
id: REACT_18103
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_18103.2

Stoichiometry2450
type: Stoichiometry
physical entity: PhysicalEntity381
stoichiometric coefficient: 1.0

SequenceSite5645
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5644
type: SequenceSite
position status: EQUAL
sequence position: 961

SequenceSite5647
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5646
type: SequenceSite
position status: EQUAL
sequence position: 961

SequenceSite5649
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5648
type: SequenceSite
position status: EQUAL
sequence position: 961

UnificationXref1776
type: UnificationXref
id: Q945M9
db: UniProt

UnificationXref1777
type: UnificationXref
id: 4196689
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196689

UnificationXref1774
type: UnificationXref
id: Q8LFU0
db: UniProt

UnificationXref1775
type: UnificationXref
id: 4196685
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196685

UnificationXref1772
type: UnificationXref
id: Q8VY64
db: UniProt

UnificationXref1773
type: UnificationXref
id: 4196681
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196681

UnificationXref1770
type: UnificationXref
id: Q9LVJ7
db: UniProt

UnificationXref1771
type: UnificationXref
id: 4196677
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196677

UnificationXref1769
type: UnificationXref
id: 4196669
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196669

UnificationXref1768
type: UnificationXref
id: 4196668
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196668

UnificationXref1767
type: UnificationXref
id: Q9SFD8
db: UniProt

Stoichiometry2402
type: Stoichiometry
physical entity: Complex772
stoichiometric coefficient: 1.0

Stoichiometry2403
type: Stoichiometry
physical entity: Protein6317
stoichiometric coefficient: 1.0

Stoichiometry2400
type: Stoichiometry
physical entity: Protein2594
stoichiometric coefficient: 1.0

Stoichiometry2401
type: Stoichiometry
physical entity: PhysicalEntity373
stoichiometric coefficient: 1.0

Stoichiometry2406
type: Stoichiometry
physical entity: Protein6327
stoichiometric coefficient: 1.0

SequenceSite5640
type: SequenceSite
position status: EQUAL
sequence position: 961

Stoichiometry2407
type: Stoichiometry
physical entity: Protein6328
stoichiometric coefficient: 1.0

SequenceSite5641
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2404
type: Stoichiometry
physical entity: PhysicalEntity374
stoichiometric coefficient: 1.0

SequenceSite5642
type: SequenceSite
position status: EQUAL
sequence position: 961

Stoichiometry2405
type: Stoichiometry
physical entity: Protein6321
stoichiometric coefficient: 1.0

SequenceSite5643
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5658
type: SequenceSite
position status: EQUAL
sequence position: 346

SequenceSite5657
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5656
type: SequenceSite
position status: EQUAL
sequence position: 346

SequenceSite5655
type: SequenceSite
position status: EQUAL
sequence position: 1

UniProt:F4JRF4
type: ProteinReference
xref: UnificationXref10758
organism: Arabidopsis thaliana

SequenceSite5659
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1763
type: UnificationXref
id: O82248
db: UniProt

UnificationXref1764
type: UnificationXref
id: 4196660
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196660

UnificationXref1765
type: UnificationXref
id: Q9FGJ3
db: UniProt

UnificationXref1766
type: UnificationXref
id: 4196664
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196664

UnificationXref1760
type: UnificationXref
id: 4196652
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196652

UnificationXref1761
type: UnificationXref
id: Q8VYK4
db: UniProt

UnificationXref1762
type: UnificationXref
id: 4196656
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196656

UnificationXref1757
type: UnificationXref
id: Q9SLG0
db: UniProt

UnificationXref1756
type: UnificationXref
id: 4196644
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196644

UnificationXref1759
type: UnificationXref
id: O04027
db: UniProt

UnificationXref1758
type: UnificationXref
id: 4196648
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196648

SequenceSite5650
type: SequenceSite
position status: EQUAL
sequence position: 961

SequenceSite5653
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5654
type: SequenceSite
position status: EQUAL
sequence position: 1970

SequenceSite5651
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5652
type: SequenceSite
position status: EQUAL
sequence position: 961

http://identifiers.org/pubmed/21029861
type: PublicationXref
id: 21029861
author: Hogg, JR
author: Goff, SP
db: Pubmed
title: Upf1 senses 3'UTR length to potentiate mRNA decay
source: Cell 143:379-89
year: 2010

PublicationXref819
type: PublicationXref
id: 0121227022
author: Parks, Jr, RE
author: Agarwal, RP
db: ISBN
title: Nucleoside diphosphokinases
source: The Enzymes, 3rd ed (Book): 307-333
year: 1973

http://identifiers.org/pubmed/11278511
type: PublicationXref
id: 11278511
author: Ding, WC
author: Berger, SH
author: Lebioda, L
author: Koli, S
author: Minor, W
author: Dunlap, RB
author: Phan, J
author: Steadman, DJ
db: Pubmed
title: Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors
source: J Biol Chem 276:14170-7
year: 2001

UnificationXref1790
type: UnificationXref
id: 4196714
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196714

SequenceSite5667
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1791
type: UnificationXref
id: Q58CM8
db: UniProt

SequenceSite5666
type: SequenceSite
position status: EQUAL
sequence position: 323

SequenceSite5669
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2419
type: Stoichiometry
physical entity: Protein6358
stoichiometric coefficient: 2.0

SequenceSite5668
type: SequenceSite
position status: EQUAL
sequence position: 308

UnificationXref1794
type: UnificationXref
id: 4196720
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196720

UnificationXref1795
type: UnificationXref
id: 4196721
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196721

UnificationXref1792
type: UnificationXref
id: 4196673
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196673

UnificationXref1793
type: UnificationXref
id: 4196715
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196715

http://identifiers.org/pubmed/59727
type: PublicationXref
id: 59727
author: Nachman, RL
author: Harpel, PC
db: Pubmed
title: Platelet alpha2-macroglobulin and alpha1-antitrypsin
source: J Biol Chem 251:4512-21
year: 1976

UnificationXref1798
type: UnificationXref
id: P43256
db: UniProt

UnificationXref1799
type: UnificationXref
id: 4184557
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184557

UnificationXref1796
type: UnificationXref
id: 4196719
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196719

UnificationXref1797
type: UnificationXref
id: 4196722
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196722

Stoichiometry2420
type: Stoichiometry
physical entity: Protein6359
stoichiometric coefficient: 2.0

Stoichiometry2421
type: Stoichiometry
physical entity: Protein6360
stoichiometric coefficient: 2.0

UnificationXref1789
type: UnificationXref
id: 4196713
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196713

Stoichiometry2428
type: Stoichiometry
physical entity: Protein6409
stoichiometric coefficient: 2.0

SequenceSite5662
type: SequenceSite
position status: EQUAL
sequence position: 309

Stoichiometry2429
type: Stoichiometry
physical entity: Protein6425
stoichiometric coefficient: 2.0

PublicationXref825
type: PublicationXref
id: 0121227022
author: Noda, L
db: ISBN
title: Adenylate kinase
source: The Enzymes, 3rd ed (Book): 279-305
year: 1973

SequenceSite5663
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2426
type: Stoichiometry
physical entity: Protein6385
stoichiometric coefficient: 2.0

SequenceSite5664
type: SequenceSite
position status: EQUAL
sequence position: 309

Stoichiometry2427
type: Stoichiometry
physical entity: Protein6400
stoichiometric coefficient: 2.0

PublicationXref823
type: PublicationXref
id: 0121227022
author: Anderson, EP
db: ISBN
title: Nucleoside and nucleotide kinases
source: The Enzymes, 3rd ed (Book): 49-96
year: 1973

SequenceSite5665
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2424
type: Stoichiometry
physical entity: Protein6370
stoichiometric coefficient: 2.0

Stoichiometry2425
type: Stoichiometry
physical entity: Protein6377
stoichiometric coefficient: 2.0

Stoichiometry2422
type: Stoichiometry
physical entity: Protein6361
stoichiometric coefficient: 2.0

SequenceSite5660
type: SequenceSite
position status: EQUAL
sequence position: 346

Stoichiometry2423
type: Stoichiometry
physical entity: Protein6367
stoichiometric coefficient: 2.0

SequenceSite5661
type: SequenceSite
position status: EQUAL
sequence position: 1

UniProt:F4JRD3
type: ProteinReference
xref: UnificationXref16088
organism: Arabidopsis thaliana

Stoichiometry2409
type: Stoichiometry
physical entity: Complex806
stoichiometric coefficient: 1.0

Stoichiometry2408
type: Stoichiometry
physical entity: Protein6331
stoichiometric coefficient: 2.0

SequenceSite5679
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5678
type: SequenceSite
position status: EQUAL
sequence position: 548

UnificationXref1780
type: UnificationXref
id: Q93ZH2
db: UniProt

SequenceSite5677
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref1781
type: UnificationXref
id: 4196697
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196697

UnificationXref1782
type: UnificationXref
id: Q84JP1
db: UniProt

UnificationXref1783
type: UnificationXref
id: 4196701
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196701

UnificationXref1784
type: UnificationXref
id: Q9LNP6
db: UniProt

UnificationXref1785
type: UnificationXref
id: 4196705
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196705

UnificationXref1786
type: UnificationXref
id: Q9M9X4
db: UniProt

http://identifiers.org/pubmed/10536157
type: PublicationXref
id: 10536157
author: Wu, X
author: Zhang, Y
author: Xin, H
author: Lin, W
author: Yuan, F
db: Pubmed
title: The human REV1 gene codes for a DNA template-dependent dCMP transferase.
source: Nucleic Acids Res 27:4468-75
year: 1999

UnificationXref1787
type: UnificationXref
id: 4196709
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196709

UnificationXref1788
type: UnificationXref
id: Q9SYH4
db: UniProt

UnificationXref1779
type: UnificationXref
id: 4196693
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196693

UnificationXref1778
type: UnificationXref
id: Q9LXV5
db: UniProt

Stoichiometry2410
type: Stoichiometry
physical entity: Protein6334
stoichiometric coefficient: 1.0

Stoichiometry2415
type: Stoichiometry
physical entity: PhysicalEntity375
stoichiometric coefficient: 1.0

SequenceSite5675
type: SequenceSite
position status: EQUAL
sequence position: 2

Stoichiometry2416
type: Stoichiometry
physical entity: PhysicalEntity376
stoichiometric coefficient: 1.0

SequenceSite5676
type: SequenceSite
position status: EQUAL
sequence position: 548

Stoichiometry2417
type: Stoichiometry
physical entity: Protein6347
stoichiometric coefficient: 1.0

SequenceSite5673
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2418
type: Stoichiometry
physical entity: Protein6350
stoichiometric coefficient: 2.0

SequenceSite5674
type: SequenceSite
position status: EQUAL
sequence position: 395

Stoichiometry2411
type: Stoichiometry
physical entity: Protein6335
stoichiometric coefficient: 2.0

SequenceSite5671
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2412
type: Stoichiometry
physical entity: Complex807
stoichiometric coefficient: 1.0

SequenceSite5672
type: SequenceSite
position status: EQUAL
sequence position: 395

Stoichiometry2413
type: Stoichiometry
physical entity: Protein6339
stoichiometric coefficient: 1.0

Stoichiometry2414
type: Stoichiometry
physical entity: Protein6343
stoichiometric coefficient: 1.0

SequenceSite5670
type: SequenceSite
position status: EQUAL
sequence position: 760

Formation of UPF1:eRF3 Complex on mRNA with a Premature Termination Codon and No Exon Junction Complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1452
xref: UnificationXref15425
xref: UnificationXref15424
left: Note: the coordinates are copied over from Homo sapiens.
left: Complex761
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex763

http://identifiers.org/pubmed/13115431
type: PublicationXref
id: 13115431
author: Lieberman, I
author: Kornberg, A
db: Pubmed
title: Enzymic synthesis and breakdown of a pyrimidine, orotic acid. I. Dihydro-orotic dehydrogenase
source: Biochim Biophys Acta 12:223-234
year: 1953

SMG1 Phosphorylates UPF1 (Enhanced by Exon Junction Complex)
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1449
EC number: 2.7.11
xref: UnificationXref15387
xref: UnificationXref15386
participant stoichiometry: Stoichiometry2073
participant stoichiometry: Stoichiometry2072
left: SmallMolecule11
left: Complex749
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex757
right: SmallMolecule14

SMG6 Cleaves mRNA with Premature Termination Codon
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1450
xref: UnificationXref15416
xref: UnificationXref15415
left: Complex758
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex760

Phosphorylated HuR (Ser221, Ser318) Binds mRNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1445
xref: UnificationXref15327
xref: UnificationXref15328
left: PhysicalEntity311
left: Homologues of p-S221,S318-ELAVL1(1-326)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex747

HuR Binds mRNAs in the Nucleus
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1446
xref: UnificationXref15337
xref: UnificationXref15336
left: PhysicalEntity312
left: Homologues of ELAVL1(1-326)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex748

KSRP Binds AU-rich Element in 3' UTR of mRNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1442
xref: UnificationXref15305
xref: UnificationXref15304
left: PhysicalEntity309
left: Homologues of KHSRP(1-710)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex745

Phosphorylated HuR (Ser221, Ser158) Binds mRNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1444
xref: UnificationXref15319
xref: UnificationXref15318
left: PhysicalEntity310
left: Homologues of p-S158,S221-ELAVL1(1-326)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex746

Initial activation of proMMP2 by MMP1, 7
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1461
EC number: 3.4.21
xref: UnificationXref15600
xref: UnificationXref15601
left: Homologues of MMP2(30-660)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Homologues of MMP2(30-66)
right: Homologues of MMP2(67-660)

IMPA1:Mg2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry90
component stoichiometry: Stoichiometry89
component: SmallMolecule49
component: Protein432
xref: UnificationXref1334
cellular location: GO:0005829
comment: Reactome DB_ID: 4197574

Full activation of MMP1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1460
EC number: 3.4.21
xref: UnificationXref15564
xref: UnificationXref15565
left: Homologues of MMP1(84-469)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Homologues of MMP1(100-469)

IMPA2 dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry94
component: IMPA2:Mg2+ (name copied from entity in Homo sapiens)
xref: UnificationXref1338
cellular location: GO:0005829
comment: Reactome DB_ID: 4197578

Autocatalytic activation of MMP1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1459
EC number: 3.4.21
xref: UnificationXref15496
xref: UnificationXref15495
left: Homologues of MMP1(54-469)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Homologues of MMP1(84-469)
right: Homologues of MMP1(54-83)

Tropoelastin forms aggregate globules
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1457
xref: UnificationXref15448
xref: UnificationXref15449
participant stoichiometry: Stoichiometry2108
left: Homologues of ELN
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex764

NUDT3:Mg2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry86
component stoichiometry: Stoichiometry85
component: SmallMolecule49
component: Protein413
xref: UnificationXref1254
cellular location: GO:0005829
comment: Reactome DB_ID: 4197649

NUDT10:Mg2+/Mn2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry87
component stoichiometry: Stoichiometry88
component: Protein421
component: SmallMolecule131
xref: UnificationXref1263
cellular location: GO:0005829
comment: Reactome DB_ID: 4197667

IMPA1/2
type: Complex
data source: Provenance1
member physical entity: IMPA2 dimer (name copied from entity in Homo sapiens)
member physical entity: IMPA1 dimer (name copied from entity in Homo sapiens)
xref: UnificationXref1339
cellular location: GO:0005829
comment: Reactome DB_ID: 4197579
comment: Converted from EntitySet in Reactome

IMPA1 dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry91
component: IMPA1:Mg2+ (name copied from entity in Homo sapiens)
xref: UnificationXref1335
cellular location: GO:0005829
comment: Reactome DB_ID: 4197575

PTEN:Mg2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry79
component stoichiometry: Stoichiometry80
component: SmallMolecule49
component: Protein368
xref: UnificationXref1060
cellular location: GO:0005829
comment: Reactome DB_ID: 4185721

ITPK1:Mg2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry82
component stoichiometry: Stoichiometry81
component: SmallMolecule49
component: Protein373
xref: UnificationXref1075
cellular location: GO:0005829
comment: Reactome DB_ID: 4197606

NUDT4:Mg2+/Mn2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry84
component stoichiometry: Stoichiometry83
component: Protein405
component: SmallMolecule131
xref: UnificationXref1235
cellular location: GO:0005829
comment: Reactome DB_ID: 4197658

NUDT(1)
type: Complex
data source: Provenance1
member physical entity: NUDT3:Mg2+ (name copied from entity in Homo sapiens)
member physical entity: NUDT10:Mg2+/Mn2+ (name copied from entity in Homo sapiens)
member physical entity: NUDT4:Mg2+/Mn2+ (name copied from entity in Homo sapiens)
xref: UnificationXref1264
cellular location: GO:0005829
display name: DIPP
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4197668

PublicationXref984
type: PublicationXref
id: 0079130356
author: Horwich, AL
author: Brusilow, SW
db: ISBN
title: Urea cycle enzymes
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 1909-1963
year: 2001

Initial activation of proMMP9 by MMPs
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1466
EC number: 3.4.21
xref: UnificationXref15731
xref: UnificationXref15730
left: Homologues of MMP9(20-707)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Homologues of MMP9(60-707)
right: Homologues of MMP9(20-59)

Activation of MMP9 intermediate form by MMPs
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1467
EC number: 3.4.21
xref: UnificationXref15754
xref: UnificationXref15755
left: Homologues of MMP9(60-707)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Homologues of MMP9(60-106)
right: Homologues of MMP9

Autocatalytic activation of proMMP2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1462
EC number: 3.4.21
xref: UnificationXref15614
xref: UnificationXref15613
left: Homologues of MMP2(67-660)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Homologues of MMP2(110-660)
right: Homologues of MMP2(67-109)

Autocatalytic activation of MMP3
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1463
EC number: 3.4.21
xref: UnificationXref15637
xref: UnificationXref15638
left: Homologues of MMP3(55-477)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Homologues of MMP3
right: Homologues of MMP3(55-99)

http://identifiers.org/pubmed/22952392
type: PublicationXref
id: 22952392
author: Nusse, Roel
author: Willert, Karl
db: Pubmed
title: Wnt proteins
source: Cold Spring Harb Perspect Biol 4:a007864
year: 2012

Activation of proMMP7 by MMP3
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1464
EC number: 3.4.21
xref: UnificationXref15661
xref: UnificationXref15662
left: Homologues of MMP7(18-267)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Homologues of MMP7(18-94)
right: Homologues of MMP7

Autocatalytic activation of MMP7
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1465
EC number: 3.4.21
xref: UnificationXref15686
xref: UnificationXref15685
left: Homologues of MMP7(51-267)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Homologues of MMP7(51-94)
right: Homologues of MMP7

Autocatalytic activation of proMMP13
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1470
EC number: 3.4.21
xref: UnificationXref15884
xref: UnificationXref15885
participant stoichiometry: Stoichiometry2110
left: PhysicalEntity328
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Homologues of MMP13
right: PhysicalEntity329

PLCH2:Ca2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry78
component stoichiometry: Stoichiometry77
component: SmallMolecule105
component: Protein358
xref: UnificationXref1044
cellular location: GO:0005886
comment: Reactome DB_ID: 4197841

Initial activation of proMMP13 by MMP14 (MT1-MMP)
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1469
EC number: 3.4.21
xref: UnificationXref15826
xref: UnificationXref15825
left: Homologues of MMP13(20-471)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Homologues of MMP13(20-54)
right: Homologues of MMP13(55-471)

Capping complex formation
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1475
xref: UnificationXref15932
xref: UnificationXref15933
left: Complex416
left: PhysicalEntity332
left: PhysicalEntity216
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex765

PLCG2:Ca2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry73
component stoichiometry: Stoichiometry74
component: Protein338
component: SmallMolecule105
xref: UnificationXref1022
cellular location: GO:0005886
comment: Reactome DB_ID: 4197819

MT-MMPs are sorted to the plasma membrane
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1471
xref: UnificationXref15922
xref: UnificationXref15921
left: PhysicalEntity330
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity331

PLCH1:Ca2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry75
component stoichiometry: Stoichiometry76
component: Protein348
component: SmallMolecule105
xref: UnificationXref1033
cellular location: GO:0005886
comment: Reactome DB_ID: 4197830

PLCD3:Ca2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry70
component stoichiometry: Stoichiometry69
component: SmallMolecule105
component: Protein318
xref: UnificationXref1000
cellular location: GO:0005886
comment: Reactome DB_ID: 4197807

PLCG1:Ca2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry72
component stoichiometry: Stoichiometry71
component: SmallMolecule105
component: Protein328
xref: UnificationXref1011
cellular location: GO:0005886
comment: Reactome DB_ID: 4197808

UniProt:F4JRI7
type: ProteinReference
xref: UnificationXref10353
organism: Arabidopsis thaliana

Initial activation of proMMP13 by MMP3
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1468
EC number: 3.4.21
xref: UnificationXref15790
xref: UnificationXref15789
left: Homologues of MMP13(20-471)
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Homologues of MMP13(77-471)
right: Homologues of MMP13(20-76)

PLCD1:Ca2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry66
component stoichiometry: Stoichiometry65
component: SmallMolecule105
component: Protein298
xref: UnificationXref978
cellular location: GO:0005886
comment: Reactome DB_ID: 4197785

PLCE1:Ca2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry67
component stoichiometry: Stoichiometry68
component: SmallMolecule105
component: Protein308
xref: UnificationXref989
cellular location: GO:0005886
comment: Reactome DB_ID: 4197796

PLCZ1:Ca2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry63
component stoichiometry: Stoichiometry64
component: Protein288
component: SmallMolecule104
xref: UnificationXref962
cellular location: GO:0005829
comment: Reactome DB_ID: 4197716

PLCdegh
type: Complex
data source: Provenance1
member physical entity: PLCH2:Ca2+ (name copied from entity in Homo sapiens)
member physical entity: PLCG1:Ca2+ (name copied from entity in Homo sapiens)
member physical entity: PLCD1:Ca2+ (name copied from entity in Homo sapiens)
member physical entity: PLCH1:Ca2+ (name copied from entity in Homo sapiens)
member physical entity: PLCD3:Ca2+ (name copied from entity in Homo sapiens)
member physical entity: PLCE1:Ca2+ (name copied from entity in Homo sapiens)
member physical entity: PLCG2:Ca2+ (name copied from entity in Homo sapiens)
xref: UnificationXref1045
cellular location: GO:0005886
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4197842

PLCB4:Ca2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry61
component stoichiometry: Stoichiometry62
component: Protein278
component: SmallMolecule104
xref: UnificationXref951
cellular location: GO:0005829
comment: Reactome DB_ID: 4197705

http://identifiers.org/pubmed/16616430
type: PublicationXref
id: 16616430
author: Conti, F
author: Varoqui, H
author: Melone, M
author: Erickson, JD
db: Pubmed
title: Localization of the Na(+)-coupled neutral amino acid transporter 2 in the cerebral cortex
source: Neuroscience 140:281-92
year: 2006

PublicationXref951
type: PublicationXref
id: 0079130356
author: Williams, JC
author: Sweetman, L
db: ISBN
title: Branched chain organic acidurias
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 2125-2163
year: 2001

Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1478
EC number: 2.7.7.50
xref: UnificationXref15949
xref: UnificationXref15948
left: Complex767
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex769

Dissociation of transcript with 5'-GMP from GT
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1479
xref: UnificationXref15954
xref: UnificationXref15953
left: Complex769
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex770

Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1476
EC number: 3.1.3.33
xref: UnificationXref15937
xref: UnificationXref15938
left: Complex765
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule921
right: Complex766

Formation of the CE:GMP intermediate complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1477
EC number: 2.7.7.50
xref: UnificationXref15943
xref: UnificationXref15944
left: SmallMolecule924
left: Complex766
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex767
right: SmallMolecule589

Methylation of GMP-cap by RNA Methyltransferase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1480
EC number: 2.1.1.56
xref: UnificationXref15961
xref: UnificationXref15960
left: SmallMolecule1093
left: Complex770
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex418
right: SmallMolecule1094
right: Complex393
right: Protein3126
right: Complex771

Formation of cap binding complex (CBC)
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1482
xref: UnificationXref15964
xref: UnificationXref15965
left: Protein2504
left: Protein2505
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex359

ACOX2:FAD (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry123
component stoichiometry: Stoichiometry124
component: Protein612
component: SmallMolecule208
xref: UnificationXref1941
cellular location: GO:0005782
comment: Reactome DB_ID: 4184768

Recognition and binding of the mRNA cap by the cap-binding complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1481
xref: UnificationXref15962
xref: UnificationXref15963
left: Complex359
left: Complex418
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex417

HSD17B4 dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry125
component: Protein615
xref: UnificationXref1951
cellular location: GO:0005782
comment: Reactome DB_ID: 4184756

ACOX1 dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry128
component: ACOX1:FAD complex (name copied from entity in Homo sapiens)
xref: UnificationXref1994
cellular location: GO:0005782
comment: Reactome DB_ID: 4189216

ACOX1:FAD complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry126
component stoichiometry: Stoichiometry127
component: Protein574
component: SmallMolecule208
xref: UnificationXref1993
cellular location: GO:0005782
comment: Reactome DB_ID: 4189215

Formation of the active Spliceosomal C complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1487
xref: UnificationXref16557
xref: UnificationXref16556
left: Complex790
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex790

Formation of an intermediate Spliceosomal C complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1486
xref: UnificationXref16555
xref: UnificationXref16554
left: Complex786
left: Complex787
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex782
right: Complex790
right: Complex779

Formation of the Spliceosomal B Complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1485
xref: UnificationXref16511
xref: UnificationXref16512
left: Complex774
left: Complex780
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex786

Internal Methylation of mRNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1484
xref: UnificationXref15976
xref: UnificationXref15975
left: Complex417
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex772

Nonsense Mediated Decay Enhanced by the Exon Junction Complex
type: Pathway
data source: Provenance1
pathway component: SMG1 Phosphorylates UPF1 (Enhanced by Exon Junction Complex)
pathway component: SMG6 Cleaves mRNA with Premature Termination Codon
evidence: Evidence1451
xref: UnificationXref15417
xref: UnificationXref15418
pathway order: PathwayStep1429
pathway order: PathwayStep1428
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

NF-Y (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry108
component stoichiometry: Stoichiometry109
component stoichiometry: Stoichiometry110
component: Protein547
component: Protein569
component: Protein558
xref: UnificationXref1793
cellular location: GO:0005654
comment: Reactome DB_ID: 4196715

SREBP1A/2 Dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry112
component: PhysicalEntity12
xref: UnificationXref1795
cellular location: GO:0005654
comment: Reactome DB_ID: 4196721

SREBP1A/1C/2:NF-Y:HMGCS1 gene (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry115
component stoichiometry: Stoichiometry118
component stoichiometry: Stoichiometry117
component: PhysicalEntity14
component: NF-Y (name copied from entity in Homo sapiens)
component: SREBP1A/1C/2 Dimer (name copied from entity in Homo sapiens)
xref: UnificationXref1821
cellular location: GO:0005654
comment: Reactome DB_ID: 4196736

SREBP1A/1C/2 Dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry116
component: PhysicalEntity15
xref: UnificationXref1820
cellular location: GO:0005654
comment: Reactome DB_ID: 4196628

HACL1 tetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry122
component: HACL1 holoenzyme monomer (name copied from entity in Homo sapiens)
xref: UnificationXref1919
cellular location: GO:0005782
comment: Reactome DB_ID: 4189076

HACL1 holoenzyme monomer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry121
component stoichiometry: Stoichiometry120
component stoichiometry: Stoichiometry119
component: Protein611
component: SmallMolecule203
component: SmallMolecule202
xref: UnificationXref1918
cellular location: GO:0005782
comment: Reactome DB_ID: 4189075

PublicationXref960
type: PublicationXref
id: 0079130356
author: Cox, RP
db: ISBN
title: Errors of lysine metabolism
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 1965-1970
year: 2001

PublicationXref962
type: PublicationXref
id: 0079130356
author: Goodman, SI
author: Frerman, FE
db: ISBN
title: Organic acidemias due to defects in lysine oxidation: 2-ketoadipic acidemia and glutaric acidemia
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 2195-2204
year: 2001

PublicationXref963
type: PublicationXref
id: 0079130356
author: Tanguay, RM
author: Mitchell, GA
author: Grompe, M
author: Lambert, M
db: ISBN
title: Hypertyrosinemia
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 1777-1805
year: 2001

Lariat Formation and 5'-Splice Site Cleavage
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1488
xref: UnificationXref16562
xref: UnificationXref16563
left: Protein2560
left: Complex790
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex792

Formation of AT-AC A complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1490
xref: UnificationXref16574
xref: UnificationXref16573
left: Protein2594
left: Protein2489
left: Protein2506
left: Complex772
left: Complex795
left: Complex794
left: Protein2515
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex796

http://identifiers.org/pubmed/15526160
type: PublicationXref
id: 15526160
author: Rönnstrand, L
db: Pubmed
title: Signal transduction via the stem cell factor receptor/c-Kit
source: Cell Mol Life Sci 61:2535-48
year: 2004

Formation of AT-AC B Complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1491
xref: UnificationXref16584
xref: UnificationXref16585
left: Complex796
left: Complex797
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex801

Formation of AT-AC C complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1492
xref: UnificationXref16587
xref: UnificationXref16588
left: Complex801
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex802
right: Complex799

UniProt:Q5XF51
type: ProteinReference
xref: UnificationXref15460
organism: Arabidopsis thaliana

PublicationXref969
type: PublicationXref
id: 0079130356
author: Thony, B
author: Blau, N
author: Cotton, RG
author: Hyland, K
db: ISBN
title: Disorders of tetrahydrobiopterin and related biogenic amines
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 1725-1776
year: 2001

ATAC spliceosome mediated Lariat formation,5' splice site cleavage
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1493
xref: UnificationXref16589
xref: UnificationXref16590
left: Complex802
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex802

AMPK heterotrimer (active) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry106
component stoichiometry: Stoichiometry105
component stoichiometry: Stoichiometry104
component: Protein534
component: Protein539
component: Protein535
xref: UnificationXref1706
cellular location: GO:0005829
comment: Reactome DB_ID: 4186621

HMGCL dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry107
component: Protein545
xref: UnificationXref1728
cellular location: GO:0005759
comment: Reactome DB_ID: 4180928

Binding of A1CF to stem-looped RNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1498
xref: UnificationXref16610
xref: UnificationXref16609
left: Protein6317
left: PhysicalEntity374
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex804

DGAT1 tetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry101
component: Protein510
xref: UnificationXref1641
cellular location: GO:0005789
comment: Reactome DB_ID: 4181482

ATAC spliceosome mediated 3' splice site cleavage, exon ligation
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1494
xref: UnificationXref16594
xref: UnificationXref16595
left: Complex802
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex803
right: Complex800
right: Complex795
right: Complex794
right: Complex775

Btn-ACACA:2Mn2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry103
component stoichiometry: Stoichiometry102
component: Protein456
component: SmallMolecule132
xref: UnificationXref1661
cellular location: GO:0005829
comment: Reactome DB_ID: 4181395

aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1503
EC number: 6.1.1.12
xref: UnificationXref16681
xref: UnificationXref16682
left: SmallMolecule1096
left: SmallMolecule11
left: SmallMolecule42
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule997
right: SmallMolecule18

arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1502
EC number: 6.1.1.19
xref: UnificationXref16676
xref: UnificationXref16677
left: SmallMolecule11
left: SmallMolecule725
left: SmallMolecule1095
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule995
right: SmallMolecule18

glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1505
EC number: 6.1.1.18
xref: UnificationXref16691
xref: UnificationXref16692
left: SmallMolecule11
left: SmallMolecule1098
left: SmallMolecule490
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule999
right: SmallMolecule18

SREBP1A/2:NF-Y:HMGCR gene (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry114
component stoichiometry: Stoichiometry113
component stoichiometry: Stoichiometry111
component: NF-Y (name copied from entity in Homo sapiens)
component: SREBP1A/2 Dimer (name copied from entity in Homo sapiens)
component: PhysicalEntity13
xref: UnificationXref1797
cellular location: GO:0005654
comment: Reactome DB_ID: 4196722

glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1504
EC number: 6.1.1.17
xref: UnificationXref16686
xref: UnificationXref16687
left: SmallMolecule11
left: SmallMolecule1097
left: SmallMolecule43
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1000
right: SmallMolecule53
right: SmallMolecule18

IMPA2:Mg2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry92
component stoichiometry: Stoichiometry93
component: Protein433
component: SmallMolecule49
xref: UnificationXref1337
cellular location: GO:0005829
comment: Reactome DB_ID: 4197577

ABCG1 dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry99
component: Protein442
xref: UnificationXref1407
cellular location: GO:0005886
comment: Reactome DB_ID: 4188038

Citrate lyase homotetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry100
component: Protein451
xref: UnificationXref1467
cellular location: GO:0005829
comment: Reactome DB_ID: 4181344

ISYNA1:NAD+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry96
component stoichiometry: Stoichiometry95
component: SmallMolecule34
component: Protein434
xref: UnificationXref1360
cellular location: GO:0005829
comment: Reactome DB_ID: 4197733

NPC1L1:ezetimibe complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry98
component stoichiometry: Stoichiometry97
component: Protein438
component: SmallMolecule160
xref: UnificationXref1395
cellular location: GO:0005886
comment: Reactome DB_ID: 4188002

UnificationXref1819
type: UnificationXref
id: 4196627
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196627

UnificationXref1818
type: UnificationXref
id: 4196735
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196735

UnificationXref1817
type: UnificationXref
id: REACT_141340
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_141340.5

UnificationXref1816
type: UnificationXref
id: 4197971
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197971

UnificationXref1815
type: UnificationXref
id: 4189214
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189214

UnificationXref1814
type: UnificationXref
id: 4189213
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189213

UnificationXref1813
type: UnificationXref
id: Q9ZQP2
db: UniProt

UnificationXref1812
type: UnificationXref
id: 4189212
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189212

UnificationXref1811
type: UnificationXref
id: O65202
db: UniProt

UnificationXref1820
type: UnificationXref
id: 4196628
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196628

PISD:Pyruvoyl (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry179
component stoichiometry: Stoichiometry177
component stoichiometry: Stoichiometry178
component: Protein777
component: SmallMolecule306
component: Protein776
xref: UnificationXref2676
cellular location: GO:0005743
comment: Reactome DB_ID: 4195930

UnificationXref1821
type: UnificationXref
id: 4196736
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196736

PCYT2 dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry176
component: Protein775
xref: UnificationXref2661
cellular location: GO:0005789
comment: Reactome DB_ID: 4195922

PCYT1A dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry180
component: Protein814
xref: UnificationXref2781
cellular location: GO:0005789
comment: Reactome DB_ID: 4195847

PCYT1 dimer
type: Complex
data source: Provenance1
member physical entity: PCYT1B dimer (name copied from entity in Homo sapiens)
member physical entity: PCYT1A dimer (name copied from entity in Homo sapiens)
xref: UnificationXref2789
cellular location: GO:0005789
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4195855

HSD11B1 dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry171
component: Protein727
xref: UnificationXref2534
cellular location: GO:0005789
comment: Reactome DB_ID: 4184887

CH25H (Fe2+ cofactor) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry169
component stoichiometry: Stoichiometry170
component: SmallMolecule285
component: Protein715
xref: UnificationXref2486
cellular location: GO:0005789
comment: Reactome DB_ID: 4184721

PHOSPHO1:Mg2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry174
component stoichiometry: Stoichiometry175
component: SmallMolecule49
component: Protein771
xref: UnificationXref2650
cellular location: GO:0005829
comment: Reactome DB_ID: 4195871

MGLL dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry173
component: Protein764
xref: UnificationXref2632
cellular location: GO:0005789
comment: Reactome DB_ID: 4195706

CDIPT:Mg2+/Mn2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry183
component stoichiometry: Stoichiometry182
component: Protein832
component: SmallMolecule323
xref: UnificationXref2856
cellular location: GO:0005789
comment: Reactome DB_ID: 4195827

PCYT1B dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry181
component: Protein820
xref: UnificationXref2788
cellular location: GO:0005789
comment: Reactome DB_ID: 4195854

UnificationXref1827
type: UnificationXref
id: REACT_140083
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_140083.5

UnificationXref1826
type: UnificationXref
id: 4197998
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197998

UnificationXref1829
type: UnificationXref
id: 4197975
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197975

UnificationXref1828
type: UnificationXref
id: Q9CA83
db: UniProt

UnificationXref1823
type: UnificationXref
id: 4196737
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196737

UnificationXref1822
type: UnificationXref
id: 4184551
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184551

UnificationXref1825
type: UnificationXref
id: 4196738
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196738

UnificationXref1824
type: UnificationXref
id: REACT_155174
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_155174.3

FDFT (Mg2+ cofactor) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry144
component stoichiometry: Stoichiometry145
component: SmallMolecule49
component: Protein652
xref: UnificationXref2144
cellular location: GO:0005789
comment: Reactome DB_ID: 4184661

UnificationXref1830
type: UnificationXref
id: B9DHW2
db: UniProt

FDPS:3Mg++ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry141
component stoichiometry: Stoichiometry140
component: SmallMolecule49
component: Protein649
xref: UnificationXref2125
cellular location: GO:0005829
comment: Reactome DB_ID: 4184545

UnificationXref1831
type: UnificationXref
id: 4197979
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197979

holo-FDPS dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry142
component: FDPS:3Mg++ (name copied from entity in Homo sapiens)
xref: UnificationXref2126
cellular location: GO:0005829
comment: Reactome DB_ID: 4184546

UnificationXref1832
type: UnificationXref
id: Q9LYG3
db: UniProt

IDI1 or 2 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry139
component stoichiometry: Stoichiometry138
component: SmallMolecule49
component: Protein646
xref: UnificationXref2114
cellular location: GO:0005829
comment: Reactome DB_ID: 4184647

MVD dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry137
component: Protein640
xref: UnificationXref2103
cellular location: GO:0005829
comment: Reactome DB_ID: 4184680

MVK dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry136
component: Protein639
xref: UnificationXref2083
cellular location: GO:0005829
comment: Reactome DB_ID: 4184635

HMGCR dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry135
component: Protein570
xref: UnificationXref2075
cellular location: GO:0005789
comment: Reactome DB_ID: 4184563

SREBP1A/2:SQLE gene (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry168
component stoichiometry: Stoichiometry166
component stoichiometry: Stoichiometry167
component: NF-Y (name copied from entity in Homo sapiens)
component: PhysicalEntity17
component: SREBP1A/2 Dimer (name copied from entity in Homo sapiens)
xref: UnificationXref2316
cellular location: GO:0005654
comment: Reactome DB_ID: 4196732

SREBP1A/1C/2:NF-Y:FDPS gene (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry163
component stoichiometry: Stoichiometry164
component stoichiometry: Stoichiometry165
component: NF-Y (name copied from entity in Homo sapiens)
component: PhysicalEntity16
component: SREBP1A/1C/2 Dimer (name copied from entity in Homo sapiens)
xref: UnificationXref2311
cellular location: GO:0005654
comment: Reactome DB_ID: 4196716

SQLE:FAD (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry147
component stoichiometry: Stoichiometry146
component: Protein656
component: SmallMolecule242
xref: UnificationXref2180
cellular location: GO:0005789
comment: Reactome DB_ID: 4184533

http://identifiers.org/pubmed/12324224
type: PublicationXref
id: 12324224
author: Sprecher, H
db: Pubmed
title: The roles of anabolic and catabolic reactions in the synthesis and recycling of polyunsaturated fatty acids
source: Prostaglandins Leukot Essent Fatty Acids 67:79-83
year: 2002

http://identifiers.org/pubmed/11533233
type: PublicationXref
id: 11533233
author: Fox, PL
author: Sonenberg, N
author: Imataka, H
author: Seshadri, V
author: Mazumder, B
db: Pubmed
title: Translational silencing of ceruloplasmin requires the essential elements of mRNA circularization: poly(A) tail, poly(A)-binding protein, and eukaryotic translation initiation factor 4G
source: Mol Cell Biol 21:6440-9
year: 2001

http://identifiers.org/pubmed/9741684
type: PublicationXref
id: 9741684
author: Edwards, PA
author: Shell, BK
author: Greene, JM
author: Ericsson, J
author: Carter, KC
author: Florence, C
author: Duan, DR
db: Pubmed
title: Human geranylgeranyl diphosphate synthase: isolation of the cDNA, chromosomal mapping and tissue expression
source: J Lipid Res 39:1731-9
year: 1998

http://identifiers.org/pubmed/10212142
type: PublicationXref
id: 10212142
author: High, S
author: Greenfield, JJ
db: Pubmed
title: The Sec61 complex is located in both the ER and the ER-Golgi intermediate compartment
source: J Cell Sci 112:1477-86
year: 1999

UnificationXref1809
type: UnificationXref
id: REACT_157305
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_157305.3

UnificationXref1808
type: UnificationXref
id: 4197999
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197999

UnificationXref1801
type: UnificationXref
id: 4184561
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184561

UnificationXref1800
type: UnificationXref
id: P14891
db: UniProt

UnificationXref1803
type: UnificationXref
id: 4196723
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196723

http://identifiers.org/pubmed/9188776
type: PublicationXref
id: 9188776
author: Rider, MH
author: Veiga-da-Cunha, M
author: Gerin, I
author: Van Schaftingen, E
author: Collet, JF
db: Pubmed
title: Human L-3-phosphoserine phosphatase: sequence, expression and evidence for a phosphoenzyme intermediate
source: FEBS Lett 408:281-4
year: 1997

UnificationXref1802
type: UnificationXref
id: 4184562
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184562

UnificationXref1805
type: UnificationXref
id: 4196724
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4196724

UnificationXref1804
type: UnificationXref
id: REACT_152948
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_152948.3

UnificationXref1807
type: UnificationXref
id: 4187854
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187854

UnificationXref1806
type: UnificationXref
id: Q84M24
db: UniProt

UnificationXref1810
type: UnificationXref
id: GO:0005782
db: GENE ONTOLOGY

Destruction of AUF1 and mRNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1436
xref: UnificationXref15256
xref: UnificationXref15255
left: Complex741
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

Butyrate Response Factor1 (BRF1) Binds AU-rich Element in 3' UTR of mRNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1438
xref: UnificationXref15268
xref: UnificationXref15267
left: PhysicalEntity307
left: Homologues of ZFP36L1
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex743

Tristetraproline (TTP) Binds AU-rich Elements in 3' UTR of Target mRNAs
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1440
xref: UnificationXref15289
xref: UnificationXref15288
left: Homologues of ZFP36
left: Homologues of TNPO1
left: PhysicalEntity308
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex744

Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1587
xref: UnificationXref17328
xref: UnificationXref17327
left: Complex567
left: SmallMolecule110
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex857
right: SmallMolecule113

CAK-mediated phosphorylation of Cyclin A:Cdk2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1586
xref: UnificationXref17318
xref: UnificationXref17319
left: Complex848
left: SmallMolecule110
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule113
right: Complex568

Mitochondrial Uncoupling Proteins
type: Pathway
data source: Provenance1
pathway component: REACT 106794.9
pathway component: REACT 105567.9
evidence: Evidence443
xref: RelationshipXref519
xref: UnificationXref4449
xref: UnificationXref4450
pathway order: PathwayStep440
pathway order: PathwayStep438
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Formation of Cyclin A:Cdk2 complexes
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1583
xref: UnificationXref17309
xref: UnificationXref17308
left: PhysicalEntity235
left: Protein6539
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex855

http://identifiers.org/pubmed/10101268
type: PublicationXref
id: 10101268
author: Heilmeyer LM, Jr
author: Gehrmann, T
author: Balla, A
author: Herberg, FW
author: Mayr, Georg W
author: Suer, S
author: Gülkan, H
author: Vereb, G
db: Pubmed
title: Functional expression and characterisation of a new human phosphatidylinositol 4-kinase PI4K230
source: Biochim Biophys Acta 1437:341-56
year: 1999

trans-Golgi Network Vesicle Budding
type: Pathway
data source: Provenance1
pathway component: REACT 101182.9
evidence: Evidence754
xref: RelationshipXref900
xref: UnificationXref7847
xref: UnificationXref7848
pathway order: PathwayStep750
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

PP2A mediated localization of RB1 protein in chromatin
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1578
EC number: 3.1.3.16
xref: UnificationXref17297
xref: UnificationXref17296
left: Complex852
left: Protein6538
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex853

Phosphorylation of Cyclin A:Cdk2 at Tyr 15
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1585
xref: UnificationXref17316
xref: UnificationXref17317
left: Complex848
left: SmallMolecule110
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex856
right: SmallMolecule113

Translocation of Cyclin A:Cdk2 complexes to the nucleus
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1584
xref: UnificationXref17310
xref: UnificationXref17311
left: Complex855
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex848

Dephosphorylation of p107 (RBL1) by PP2A
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1571
EC number: 3.1.3.16
xref: UnificationXref17264
xref: UnificationXref17265
participant stoichiometry: Stoichiometry2489
participant stoichiometry: Stoichiometry2488
left: SmallMolecule534
left: Protein6502
display name: Dephosphorylation of p107 by PP2A
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule921
right: Protein6500

Homologues of 4xHC-COX17(2-63)
type: Protein
data source: Provenance1
member physical entity: COX17_HUMAN
xref: UnificationXref14579
cellular location: GO:0005758
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4195335

p130 (RBL2) binds Cyclin E/A:CDK2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1569
xref: UnificationXref17221
xref: UnificationXref17222
left: Complex848
left: Protein6501
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex850

COX17_HUMAN
type: Protein
entity reference: Q94FT1
data source: Provenance1
name: COX17 (disulfide-bonded)
name: Note: the coordinates are copied over from Homo sapiens.
name: Q94FT1
name: 4xHC-COX17(2-63)
name: Cytochrome c oxidase copper chaperone
xref: UnificationXref14575
feature: FragmentFeature4270
feature: ModificationFeature338
feature: ModificationFeature337
feature: ModificationFeature340
feature: ModificationFeature339
cellular location: GO:0005758
comment: Reactome DB_ID: 4195319
display name: COX17

Detection of damage during initiation of DNA synthesis in S-phase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1577
xref: UnificationXref17291
xref: UnificationXref17292
left: Complex565
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex852
right: Complex562

COX17_HUMAN
type: Protein
entity reference: Q9LJQ9
data source: Provenance1
name: COX17 (disulfide-bonded)
name: Note: the coordinates are copied over from Homo sapiens.
name: 4xHC-COX17(2-63)
name: Cytochrome c oxidase copper chaperone
name: Q9LJQ9
xref: UnificationXref14576
feature: ModificationFeature341
feature: ModificationFeature342
feature: ModificationFeature343
feature: ModificationFeature344
feature: FragmentFeature4271
cellular location: GO:0005758
comment: Reactome DB_ID: 4195324
display name: COX17

Dephosphorylation of p130 (RBL2) by PP2A
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1572
EC number: 3.1.3.16
xref: UnificationXref17268
xref: UnificationXref17267
participant stoichiometry: Stoichiometry2493
participant stoichiometry: Stoichiometry2494
left: SmallMolecule534
left: Protein6528
display name: Dephosphorylation of p107 by PP2A
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule921
right: Protein6501

COX17_HUMAN
type: Protein
entity reference: Q8LFR7
data source: Provenance1
name: COX17 (disulfide-bonded)
name: Note: the coordinates are copied over from Homo sapiens.
name: 4xHC-COX17(2-63)
name: Cytochrome c oxidase copper chaperone
name: Q8LFR7
xref: UnificationXref14577
feature: ModificationFeature348
feature: FragmentFeature4272
feature: ModificationFeature347
feature: ModificationFeature346
feature: ModificationFeature345
cellular location: GO:0005758
comment: Reactome DB_ID: 4195329
display name: COX17

Q9XH48
type: Protein
entity reference: Q9XH48
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: TIM13_HUMAN
name: Mitochondrial import inner membrane translocase subunit Tim13
xref: UnificationXref14568
feature: FragmentFeature4266
cellular location: GO:0005758
comment: Reactome DB_ID: 4195307
display name: TIMM13

UnificationXref6070
type: UnificationXref
id: 4177225
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177225

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9XGY4
data source: Provenance1
name: Q9XGY4
name: TIM8A_HUMAN
name: Mitochondrial import inner membrane translocase subunit Tim8 A
xref: UnificationXref14570
feature: FragmentFeature4267
cellular location: GO:0005758
comment: Reactome DB_ID: 4195311
display name: TIMM8A

UnificationXref6071
type: UnificationXref
id: C0Z3A0
db: UniProt

Mitochondrial import inner membrane translocase subunit Tim8 B
type: Protein
entity reference: Q9XGY4
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q9XGY4
name: TIMM8B(2-83)
name: TIM8B_HUMAN
xref: UnificationXref14571
feature: FragmentFeature4268
cellular location: GO:0005758
comment: Reactome DB_ID: 4195312
display name: TIMM8B

UnificationXref6072
type: UnificationXref
id: 4177228
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177228

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9XGX9
data source: Provenance1
name: TIM9_HUMAN
name: TIMM9(2-89)
name: Mitochondrial import inner membrane translocase subunit Tim9
name: Q9XGX9
xref: UnificationXref14573
feature: FragmentFeature4269
cellular location: GO:0005758
comment: Reactome DB_ID: 4195313
display name: TIMM9

UnificationXref6073
type: UnificationXref
id: Q9M7Z1
db: UniProt

UnificationXref6075
type: UnificationXref
id: O64968
db: UniProt

UnificationXref6074
type: UnificationXref
id: 4177231
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177231

UnificationXref6077
type: UnificationXref
id: C0Z3C1
db: UniProt

UnificationXref6076
type: UnificationXref
id: 4177234
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177234

UnificationXref6079
type: UnificationXref
id: 4177238
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177238

UnificationXref6078
type: UnificationXref
id: 4177237
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177237

UnificationXref6080
type: UnificationXref
id: 4177239
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177239

UnificationXref6083
type: UnificationXref
id: CHEBI:15486
db: ChEBI

UnificationXref6084
type: UnificationXref
id: 70744
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=70744

UnificationXref6081
type: UnificationXref
id: 4177241
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177241

UnificationXref6082
type: UnificationXref
id: REACT_34280
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_34280.10

UnificationXref6088
type: UnificationXref
id: 4177246
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177246

UnificationXref6087
type: UnificationXref
id: 4177245
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177245

UnificationXref6086
type: UnificationXref
id: Q9SWG0
db: UniProt

UnificationXref6085
type: UnificationXref
id: REACT_4351
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4351.2

UnificationXref6089
type: UnificationXref
id: 4177248
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177248

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LHE5
data source: Provenance1
name: Q9LHE5
name: Mitochondrial import receptor subunit TOM40 homolog
name: TOM40_HUMAN
xref: UnificationXref14601
feature: FragmentFeature4282
cellular location: GO:0005758
comment: Reactome DB_ID: 4194760
display name: TOMM40

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SX55
data source: Provenance1
name: Q9SX55
name: Mitochondrial import receptor subunit TOM40 homolog
name: TOM40_HUMAN
xref: UnificationXref14603
feature: FragmentFeature4283
cellular location: GO:0005758
comment: Reactome DB_ID: 4194761
display name: TOMM40

Homologues of VDAC1
type: Protein
data source: Provenance1
member physical entity: Voltage-dependent anion-selective channel protein 1
xref: UnificationXref14619
cellular location: GO:0005758
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4194788

Voltage-dependent anion-selective channel protein 1
type: Protein
entity reference: Q9M2W6
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q9M2W6
name: VDAC1_HUMAN
xref: UnificationXref14606
feature: FragmentFeature4284
cellular location: GO:0005758
comment: Reactome DB_ID: 4194767
display name: VDAC1

UniProt:F4K3R8
type: ProteinReference
xref: UnificationXref14613
organism: Arabidopsis thaliana

Voltage-dependent anion-selective channel protein 1
type: Protein
entity reference: Q9FKM2
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q9FKM2
name: VDAC1_HUMAN
xref: UnificationXref14608
feature: FragmentFeature4285
cellular location: GO:0005758
comment: Reactome DB_ID: 4194771
display name: VDAC1

UnificationXref6050
type: UnificationXref
id: O82450
db: UniProt

http://identifiers.org/pubmed/15175005
type: PublicationXref
id: 15175005
author: Stewart, AJ
author: Sadler, PJ
author: Roberts, SJ
author: Farquharson, C
db: Pubmed
title: Human PHOSPHO1 exhibits high specific phosphoethanolamine and phosphocholine phosphatase activities
source: Biochem J 382:59-65
year: 2004

Voltage-dependent anion-selective channel protein 1
type: Protein
entity reference: Q9SRH5
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: VDAC1_HUMAN
name: Q9SRH5
xref: UnificationXref14610
feature: FragmentFeature4286
cellular location: GO:0005758
comment: Reactome DB_ID: 4194775
display name: VDAC1

UnificationXref6051
type: UnificationXref
id: 4177213
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177213

Voltage-dependent anion-selective channel protein 1
type: Protein
entity reference: F4IZ90
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: F4IZ90
name: VDAC1_HUMAN
xref: UnificationXref14612
feature: FragmentFeature4287
cellular location: GO:0005758
comment: Reactome DB_ID: 4194777
display name: VDAC1

Voltage-dependent anion-selective channel protein 1
type: Protein
entity reference: UniProt:F4K3R8
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: VDAC1_HUMAN
name: F4K3R8
xref: UnificationXref14614
feature: FragmentFeature4288
cellular location: GO:0005758
comment: Reactome DB_ID: 4194781
display name: VDAC1

Voltage-dependent anion-selective channel protein 1
type: Protein
entity reference: Q9FJX3
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: VDAC1_HUMAN
name: Q9FJX3
xref: UnificationXref14616
feature: FragmentFeature4289
cellular location: GO:0005758
comment: Reactome DB_ID: 4194783
display name: VDAC1

Voltage-dependent anion-selective channel protein 1
type: Protein
entity reference: Q9SMX3
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q9SMX3
name: VDAC1_HUMAN
xref: UnificationXref14618
feature: FragmentFeature4290
cellular location: GO:0005758
comment: Reactome DB_ID: 4194787
display name: VDAC1

UnificationXref6057
type: UnificationXref
id: F4KIN4
db: UniProt

Homologues of TOMM40
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14604
cellular location: GO:0005758
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4194762

UnificationXref6056
type: UnificationXref
id: 4177190
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177190

UnificationXref6059
type: UnificationXref
id: Q9ZT57
db: UniProt

UnificationXref6058
type: UnificationXref
id: 4177194
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177194

UnificationXref6053
type: UnificationXref
id: 4177215
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177215

UnificationXref6052
type: UnificationXref
id: Q9SAV3
db: UniProt

UnificationXref6055
type: UnificationXref
id: Q9FY85
db: UniProt

UnificationXref6054
type: UnificationXref
id: 4177216
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177216

http://identifiers.org/pubmed/11322953
type: PublicationXref
id: 11322953
author: Ishida, N
author: Kawakita, M
author: Muraoka, M
db: Pubmed
title: Molecular characterization of human UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter, a novel nucleotide sugar transporter with dual substrate specificity
source: FEBS Lett 495:87-93
year: 2001

Q9XH48
type: Protein
entity reference: Q9XH48
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: TIMM13 (disulfide-bonded)
name: 4xHC-TIMM13
name: TIM13_HUMAN
name: Mitochondrial import inner membrane translocase subunit Tim13
xref: UnificationXref14581
feature: ModificationFeature359
feature: ModificationFeature357
feature: ModificationFeature360
feature: ModificationFeature358
feature: FragmentFeature4275
cellular location: GO:0005758
comment: Reactome DB_ID: 4195340
display name: TIMM13

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9XGX9
data source: Provenance1
name: TIM9_HUMAN
name: TIMM9 (disulfide-bonded)
name: 4xHC-TIMM9(2-89)
name: Mitochondrial import inner membrane translocase subunit Tim9
name: Q9XGX9
xref: UnificationXref14584
feature: FragmentFeature4278
feature: ModificationFeature369
feature: ModificationFeature370
feature: ModificationFeature371
feature: ModificationFeature372
cellular location: GO:0005743
comment: Reactome DB_ID: 4195269
display name: TIMM9

UnificationXref6061
type: UnificationXref
id: F4KCJ8
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GYJ4
data source: Provenance1
name: MIA40_HUMAN
name: Q8GYJ4
name: CHCHD4 (MIA40)
name: Mitochondrial intermembrane space import and assembly protein 40
xref: UnificationXref14587
feature: FragmentFeature4279
cellular location: GO:0005758
comment: Reactome DB_ID: 4195355
display name: CHCHD4

UnificationXref6062
type: UnificationXref
id: 4177200
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177200

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9XGY4
data source: Provenance1
name: TIMM8A (disulfide-bonded)
name: Q9XGY4
name: TIM8A_HUMAN
name: Mitochondrial import inner membrane translocase subunit Tim8 A
name: 4xHC-TIMM8A
xref: UnificationXref14582
feature: ModificationFeature363
feature: FragmentFeature4276
feature: ModificationFeature362
feature: ModificationFeature361
feature: ModificationFeature364
cellular location: GO:0005758
comment: Reactome DB_ID: 4195345
display name: TIMM8A

Mitochondrial import inner membrane translocase subunit Tim8 B
type: Protein
entity reference: Q9XGY4
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: TIMM8B (disulfide-bonded)
name: Q9XGY4
name: TIM8B_HUMAN
name: 4xHC-TIMM8B(2-83)
xref: UnificationXref14583
feature: ModificationFeature368
feature: ModificationFeature367
feature: ModificationFeature365
feature: FragmentFeature4277
feature: ModificationFeature366
cellular location: GO:0005758
comment: Reactome DB_ID: 4195350
display name: TIMM8B

UnificationXref6060
type: UnificationXref
id: 4177198
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177198

adenine nucleotide translocator 3
type: Protein
entity reference: ProteinReference602
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Adenine nucleotide translocator 3
name: ADP/ATP translocase 3 monomer
name: SLC25A6
name: AT5G56450.1
name: ADP/ATP translocase 3
name: ADP,ATP carrier protein, liver isoform T2
xref: UnificationXref14594
feature: FragmentFeature4281
cellular location: GO:0005758
comment: Reactome DB_ID: 4195271
display name: ANT 3

Proteins Chaperoned by TIMM9:TIMM10
type: Protein
data source: Provenance1
member physical entity: Protein1244
xref: UnificationXref14596
cellular location: GO:0005743
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4195273

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8GXX0
data source: Provenance1
name: ALR_HUMAN
name: GFER (ERV1)
name: FAD-linked sulfhydryl oxidase ALR
name: Q8GXX0
xref: UnificationXref14589
feature: FragmentFeature4280
cellular location: GO:0005758
comment: Reactome DB_ID: 4195359
display name: GFER

Proteins Chaperoned by TIMM9:TIMM10
type: Protein
data source: Provenance1
member physical entity: adenine nucleotide translocator 3
xref: UnificationXref14595
cellular location: GO:0005758
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4195272

UnificationXref6069
type: UnificationXref
id: Q9M724
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZW33
data source: Provenance1
name: Q9ZW33
name: TIMM10 (disulfide-bonded)
name: TIM10_HUMAN
name: Mitochondrial import inner membrane translocase subunit Tim10
name: 4xHC-TIMM10
xref: UnificationXref14580
feature: ModificationFeature353
feature: ModificationFeature356
feature: ModificationFeature354
feature: FragmentFeature4274
feature: ModificationFeature355
cellular location: GO:0005743
comment: Reactome DB_ID: 4195261
display name: TIMM10

UnificationXref6068
type: UnificationXref
id: 4177217
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177217

COX17_HUMAN
type: Protein
entity reference: Q2HIR2
data source: Provenance1
name: COX17 (disulfide-bonded)
name: Note: the coordinates are copied over from Homo sapiens.
name: 4xHC-COX17(2-63)
name: Cytochrome c oxidase copper chaperone
name: Q2HIR2
xref: UnificationXref14578
feature: FragmentFeature4273
feature: ModificationFeature350
feature: ModificationFeature351
feature: ModificationFeature349
feature: ModificationFeature352
cellular location: GO:0005758
comment: Reactome DB_ID: 4195334
display name: COX17

UnificationXref6067
type: UnificationXref
id: 4177205
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177205

UnificationXref6066
type: UnificationXref
id: 4177204
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177204

UnificationXref6065
type: UnificationXref
id: Q84JL2
db: UniProt

UnificationXref6064
type: UnificationXref
id: 4177202
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177202

UnificationXref6063
type: UnificationXref
id: Q9LPL5
db: UniProt

A1XJK0
type: Protein
entity reference: A1XJK0
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Mitochondrial import inner membrane translocase subunit Tim22
name: TIM22_HUMAN
xref: UnificationXref14649
feature: FragmentFeature4306
cellular location: GO:0005758
comment: Reactome DB_ID: 4195368
display name: TIMM22

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: A2RVP7
data source: Provenance1
name: Mitochondrial import inner membrane translocase subunit Tim22
name: A2RVP7
name: TIM22_HUMAN
xref: UnificationXref14647
feature: FragmentFeature4305
cellular location: GO:0005758
comment: Reactome DB_ID: 4195366
display name: TIMM22

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O64471
data source: Provenance1
name: O64471
name: Metaxin-2
name: MTX2_HUMAN
xref: UnificationXref14641
feature: FragmentFeature4303
cellular location: GO:0005741
comment: Reactome DB_ID: 4194806
display name: MTX2

SAM50_HUMAN
type: Protein
entity reference: Q8LEH7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q8LEH7
name: Sorting and assembly machinery component 50 homolog
xref: UnificationXref14638
feature: FragmentFeature4302
cellular location: GO:0005741
comment: Reactome DB_ID: 4194816
display name: SAMM50

Homologues of TIMM22
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: A1XJK0
xref: UnificationXref14652
cellular location: GO:0005758
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4195373

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O64471
data source: Provenance1
name: MTX1_HUMAN
name: Metaxin-1
name: O64471
xref: UnificationXref14642
feature: FragmentFeature4304
cellular location: GO:0005741
comment: Reactome DB_ID: 4194805
display name: MTX1

proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1513
EC number: 6.1.1.15
xref: UnificationXref16752
xref: UnificationXref16751
left: SmallMolecule11
left: SmallMolecule884
left: SmallMolecule1106
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1008
right: SmallMolecule18

Homologues of SAMM50
type: Protein
data source: Provenance1
member physical entity: SAM50_HUMAN
member physical entity: Q9FFG3
xref: UnificationXref14639
cellular location: GO:0005741
comment: Reactome DB_ID: 4194817
comment: Converted from EntitySet in Reactome

malate dehydrogenase 1 dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry24
component: Homologues of MDH1
xref: UnificationXref320
cellular location: GO:0005829
comment: Reactome DB_ID: 4185526

serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1514
EC number: 6.1.1.11
xref: UnificationXref16759
xref: UnificationXref16760
left: SmallMolecule11
left: SmallMolecule417
left: SmallMolecule1107
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1009
right: SmallMolecule18

Voltage-dependent anion-selective channel protein 1
type: Protein
entity reference: Q9SMX3
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q9SMX3
name: VDAC1_HUMAN
xref: UnificationXref14630
feature: FragmentFeature4299
cellular location: GO:0005741
comment: Reactome DB_ID: 4194799
display name: VDAC1

pyruvate carboxylase holoenzyme (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry21
component stoichiometry: Stoichiometry23
component stoichiometry: Stoichiometry22
component: SmallMolecule28
component: SmallMolecule29
component: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref272
cellular location: GO:0005759
comment: Reactome DB_ID: 4177000

threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1515
EC number: 6.1.1.3
xref: UnificationXref16776
xref: UnificationXref16777
left: SmallMolecule11
left: SmallMolecule1108
left: SmallMolecule885
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1010
right: SmallMolecule18

SAM50_HUMAN
type: Protein
entity reference: Q9SRL6
data source: Provenance1
name: Q9SRL6
name: Note: the coordinates are copied over from Homo sapiens.
name: Sorting and assembly machinery component 50 homolog
xref: UnificationXref14636
feature: FragmentFeature4301
cellular location: GO:0005741
comment: Reactome DB_ID: 4194814
display name: SAMM50

triosephosphate isomerase dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry20
component: Homologues of TPI1
xref: UnificationXref242
cellular location: GO:0005829
comment: Reactome DB_ID: 4176923

tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1516
EC number: 6.1.1.2
xref: UnificationXref16788
xref: UnificationXref16787
left: SmallMolecule1109
left: SmallMolecule11
left: SmallMolecule886
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1011
right: SmallMolecule18

Q9FFG3
type: Protein
entity reference: Q9FFG3
data source: Provenance1
name: SAM50_HUMAN
name: Note: the coordinates are copied over from Homo sapiens.
name: Sorting and assembly machinery component 50 homolog
xref: UnificationXref14634
feature: FragmentFeature4300
cellular location: GO:0005741
comment: Reactome DB_ID: 4194810
display name: SAMM50

ALDOB tetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry19
component: Homologues of ALDOB
xref: UnificationXref234
cellular location: GO:0005829
comment: Reactome DB_ID: 4176810

leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1509
EC number: 6.1.1.4
xref: UnificationXref16727
xref: UnificationXref16726
left: SmallMolecule11
left: SmallMolecule1102
left: SmallMolecule882
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1004
right: SmallMolecule18

phosphofructokinase, PL3 complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry18
component stoichiometry: Stoichiometry17
component: Homologues of PFKP
component: Homologues of PFKL
xref: UnificationXref189
cellular location: GO:0005829
comment: Reactome DB_ID: 4176967

lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1510
EC number: 6.1.1.6
xref: UnificationXref16731
xref: UnificationXref16732
left: SmallMolecule11
left: SmallMolecule1103
left: SmallMolecule883
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1005
right: SmallMolecule18

phosphofructokinase, P2L2 complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry15
component stoichiometry: Stoichiometry16
component: Homologues of PFKP
component: Homologues of PFKL
xref: UnificationXref188
cellular location: GO:0005829
comment: Reactome DB_ID: 4176966

methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1511
EC number: 6.1.1.10
xref: UnificationXref16736
xref: UnificationXref16737
left: SmallMolecule11
left: SmallMolecule672
left: SmallMolecule1104
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1006
right: SmallMolecule18

phosphofructokinase, P3L complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry13
component stoichiometry: Stoichiometry14
component: Homologues of PFKP
component: Homologues of PFKL
xref: UnificationXref187
cellular location: GO:0005829
comment: Reactome DB_ID: 4176965

phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1512
EC number: 6.1.1.20
xref: UnificationXref16746
xref: UnificationXref16747
left: SmallMolecule11
left: SmallMolecule1105
left: SmallMolecule462
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1007
right: SmallMolecule18

phosphofructokinase, P4 complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry12
component: Homologues of PFKP
xref: UnificationXref186
cellular location: GO:0005829
comment: Reactome DB_ID: 4176964

histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1507
EC number: 6.1.1.21
xref: UnificationXref16716
xref: UnificationXref16717
left: SmallMolecule11
left: SmallMolecule701
left: SmallMolecule1100
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1002
right: SmallMolecule18

glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1506
EC number: 6.1.1.14
xref: UnificationXref16705
xref: UnificationXref16704
left: SmallMolecule11
left: SmallMolecule492
left: SmallMolecule1099
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1001
right: SmallMolecule18

GOT2 dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry25
component: Protein102
xref: UnificationXref335
cellular location: GO:0005759
comment: Reactome DB_ID: 4177150

isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1508
EC number: 6.1.1.5
xref: UnificationXref16722
xref: UnificationXref16721
left: SmallMolecule11
left: SmallMolecule1101
left: SmallMolecule881
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1003
right: SmallMolecule18

SLC25A11 homodimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry26
component: Protein103
xref: UnificationXref345
cellular location: GO:0005743
comment: Reactome DB_ID: 4185510

UniProt:F4K456
type: ProteinReference
xref: UnificationXref16086
organism: Arabidopsis thaliana

UniProt:F4K455
type: ProteinReference
xref: UnificationXref16080
organism: Arabidopsis thaliana

asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1520
EC number: 6.1.1.22
xref: UnificationXref16822
xref: UnificationXref16823
left: SmallMolecule1113
left: SmallMolecule1112
left: SmallMolecule22
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule479
right: SmallMolecule1114
right: SmallMolecule440

Voltage-dependent anion-selective channel protein 1
type: Protein
entity reference: Q9FJX3
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: VDAC1_HUMAN
name: Q9FJX3
xref: UnificationXref14629
feature: FragmentFeature4298
cellular location: GO:0005741
comment: Reactome DB_ID: 4194798
display name: VDAC1

Voltage-dependent anion-selective channel protein 1
type: Protein
entity reference: UniProt:F4K3R8
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: VDAC1_HUMAN
name: F4K3R8
xref: UnificationXref14628
feature: FragmentFeature4297
cellular location: GO:0005741
comment: Reactome DB_ID: 4194797
display name: VDAC1

Voltage-dependent anion-selective channel protein 1
type: Protein
entity reference: F4IZ90
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: F4IZ90
name: VDAC1_HUMAN
xref: UnificationXref14627
feature: FragmentFeature4296
cellular location: GO:0005741
comment: Reactome DB_ID: 4194796
display name: VDAC1

Voltage-dependent anion-selective channel protein 1
type: Protein
entity reference: Q9SRH5
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: VDAC1_HUMAN
name: Q9SRH5
xref: UnificationXref14626
feature: FragmentFeature4295
cellular location: GO:0005741
comment: Reactome DB_ID: 4194795
display name: VDAC1

Voltage-dependent anion-selective channel protein 1
type: Protein
entity reference: Q9FKM2
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q9FKM2
name: VDAC1_HUMAN
xref: UnificationXref14625
feature: FragmentFeature4294
cellular location: GO:0005741
comment: Reactome DB_ID: 4194794
display name: VDAC1

Voltage-dependent anion-selective channel protein 1
type: Protein
entity reference: Q9M2W6
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q9M2W6
name: VDAC1_HUMAN
xref: UnificationXref14624
feature: FragmentFeature4293
cellular location: GO:0005741
comment: Reactome DB_ID: 4194793
display name: VDAC1

Homologues of VDAC1
type: Protein
data source: Provenance1
member physical entity: Voltage-dependent anion-selective channel protein 1
xref: UnificationXref14631
cellular location: GO:0005741
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4194800

leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1527
EC number: 6.1.1.4
xref: UnificationXref16905
xref: UnificationXref16906
left: SmallMolecule1130
left: SmallMolecule1131
left: SmallMolecule22
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule479
right: SmallMolecule440
right: SmallMolecule1132

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SX55
data source: Provenance1
name: Q9SX55
name: Mitochondrial import receptor subunit TOM40 homolog
name: TOM40_HUMAN
xref: UnificationXref14622
feature: FragmentFeature4292
cellular location: GO:0005741
comment: Reactome DB_ID: 4194791
display name: TOMM40

lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1528
EC number: 6.1.1.6
xref: UnificationXref16915
xref: UnificationXref16916
left: SmallMolecule703
left: SmallMolecule22
left: SmallMolecule1133
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule479
right: SmallMolecule1134
right: SmallMolecule440

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LHE5
data source: Provenance1
name: Q9LHE5
name: Mitochondrial import receptor subunit TOM40 homolog
name: TOM40_HUMAN
xref: UnificationXref14621
feature: FragmentFeature4291
cellular location: GO:0005741
comment: Reactome DB_ID: 4194790
display name: TOMM40

histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1525
EC number: 6.1.1.21
xref: UnificationXref16876
xref: UnificationXref16877
left: SmallMolecule1124
left: SmallMolecule1125
left: SmallMolecule22
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1126
right: SmallMolecule479
right: SmallMolecule440

Homologues of TOMM40
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14623
cellular location: GO:0005741
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4194792

isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1526
EC number: 6.1.1.5
xref: UnificationXref16895
xref: UnificationXref16896
left: SmallMolecule1127
left: SmallMolecule1128
left: SmallMolecule22
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule479
right: SmallMolecule440
right: SmallMolecule1129

glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1523
EC number: 6.1.1.18
xref: UnificationXref16855
xref: UnificationXref16854
left: SmallMolecule22
left: SmallMolecule1119
left: SmallMolecule1120
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule479
right: SmallMolecule440
right: SmallMolecule1121

glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1524
EC number: 6.1.1.14
xref: UnificationXref16866
xref: UnificationXref16865
left: SmallMolecule756
left: SmallMolecule22
left: SmallMolecule1122
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule479
right: SmallMolecule1123
right: SmallMolecule440

aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1521
EC number: 6.1.1.12
xref: UnificationXref16835
xref: UnificationXref16834
left: SmallMolecule1115
left: SmallMolecule22
left: SmallMolecule40
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule479
right: SmallMolecule1116
right: SmallMolecule440

glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1522
EC number: 6.1.1.17
xref: UnificationXref16842
xref: UnificationXref16843
left: SmallMolecule1117
left: SmallMolecule38
left: SmallMolecule22
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule479
right: SmallMolecule440
right: SmallMolecule1118

valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1518
EC number: 6.1.1.9
xref: UnificationXref16803
xref: UnificationXref16802
left: SmallMolecule11
left: SmallMolecule1111
left: SmallMolecule887
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1013
right: SmallMolecule18

tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1517
EC number: 6.1.1.1
xref: UnificationXref16796
xref: UnificationXref16795
left: SmallMolecule11
left: SmallMolecule1110
left: SmallMolecule710
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: SmallMolecule1012
right: SmallMolecule18

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LYG1
data source: Provenance1
name: TI17A_HUMAN
name: TIMM17A
name: Mitochondrial import inner membrane translocase subunit Tim17-A
xref: UnificationXref14679
feature: FragmentFeature4320
cellular location: GO:0005743
comment: Reactome DB_ID: 4195108
display name: Q9LYG1

UnificationXref6093
type: UnificationXref
id: CHEBI:15488
db: ChEBI

Homologues of TIMM17A
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14688
cellular location: GO:0005743
comment: Reactome DB_ID: 4195121
comment: Converted from EntitySet in Reactome

UnificationXref6092
type: UnificationXref
id: REACT_2670
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2670.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q6S709
data source: Provenance1
name: TI17A_HUMAN
name: TIMM17A
name: Mitochondrial import inner membrane translocase subunit Tim17-A
xref: UnificationXref14683
feature: FragmentFeature4322
cellular location: GO:0005743
comment: Reactome DB_ID: 4195112
display name: Q6S709

UnificationXref6095
type: UnificationXref
id: REACT_3130
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3130.2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LAB0
data source: Provenance1
name: TI17A_HUMAN
name: TIMM17A
name: Mitochondrial import inner membrane translocase subunit Tim17-A
xref: UnificationXref14681
feature: FragmentFeature4321
cellular location: GO:0005743
comment: Reactome DB_ID: 4195110
display name: Q8LAB0

UnificationXref6094
type: UnificationXref
id: 70772
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=70772

G6PD tetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry46
component stoichiometry: Stoichiometry47
component: Protein128
component: SmallMolecule58
xref: UnificationXref489
cellular location: GO:0005829
comment: Reactome DB_ID: 4176829

G6PD dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry44
component stoichiometry: Stoichiometry45
component: Protein128
component: SmallMolecule58
xref: UnificationXref488
cellular location: GO:0005829
comment: Reactome DB_ID: 4176828

phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1530
EC number: 6.1.1.20
xref: UnificationXref16940
xref: UnificationXref16941
left: SmallMolecule1138
left: SmallMolecule1139
left: SmallMolecule22
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule479
right: SmallMolecule440
right: SmallMolecule1140

UnificationXref6091
type: UnificationXref
id: 29896
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29896

http://identifiers.org/pubmed/11459976
type: PublicationXref
id: 11459976
author: Bell, SP
author: Klemm, RD
db: Pubmed
title: ATP bound to the origin recognition complex is important for preRC formation.
source: Proc Natl Acad Sci U S A 98:8361-7
year: 2001

serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1531
EC number: 6.1.1.11
xref: UnificationXref16959
xref: UnificationXref16958
left: SmallMolecule1142
left: SmallMolecule22
left: SmallMolecule1141
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule479
right: SmallMolecule440
right: SmallMolecule1143

UnificationXref6090
type: UnificationXref
id: REACT_32004
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_32004.10

threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1532
EC number: 6.1.1.3
xref: UnificationXref16972
xref: UnificationXref16973
left: SmallMolecule22
left: SmallMolecule1145
left: SmallMolecule1144
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule479
right: SmallMolecule440
right: SmallMolecule1146

GUSB tetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry50
component: Protein166
xref: UnificationXref633
cellular location: GO:0043202
comment: Reactome DB_ID: 4197171

tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1533
EC number: 6.1.1.2
xref: UnificationXref16988
xref: UnificationXref16989
left: SmallMolecule1148
left: SmallMolecule22
left: SmallMolecule1147
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule479
right: SmallMolecule440
right: SmallMolecule1149

phosphoribosyl pyrophosphate synthetase holoenzyme
type: Complex
data source: Provenance1
member physical entity: phosphoribosyl pyrophosphate synthetase 1 holoenzyme (name copied from entity in Homo sapiens)
xref: UnificationXref607
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4180307

tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1534
EC number: 6.1.1.1
xref: UnificationXref16999
xref: UnificationXref17000
left: SmallMolecule1151
left: SmallMolecule1150
left: SmallMolecule22
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1152
right: SmallMolecule479
right: SmallMolecule440

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q38820
data source: Provenance1
name: TIM23_HUMAN
name: Mitochondrial import inner membrane translocase subunit Tim23
name: Q38820
xref: UnificationXref14667
feature: FragmentFeature4315
cellular location: GO:0005743
comment: Reactome DB_ID: 4195093
display name: TIMM23

phosphoribosyl pyrophosphate synthetase 1 holoenzyme (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry49
component: Protein162
xref: UnificationXref602
cellular location: GO:0005829
comment: Reactome DB_ID: 4180306

valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1535
EC number: 6.1.1.9
xref: UnificationXref17009
xref: UnificationXref17008
left: SmallMolecule1153
left: SmallMolecule22
left: SmallMolecule1154
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule479
right: SmallMolecule440
right: SmallMolecule1155

Homologues of TIMM23
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14671
cellular location: GO:0005743
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4195104

RPE dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry48
component: Protein137
xref: UnificationXref522
cellular location: GO:0005829
comment: Reactome DB_ID: 4177523

Exportin-5 recognizes 3' overhang of pre-miRNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1539
xref: UnificationXref17032
xref: UnificationXref17033
left: Complex819
left: PhysicalEntity378
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex821

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9S837
data source: Provenance1
name: Q9S837
name: TIM23_HUMAN
name: Mitochondrial import inner membrane translocase subunit Tim23
xref: UnificationXref14669
feature: FragmentFeature4317
cellular location: GO:0005743
comment: Reactome DB_ID: 4195101
display name: TIMM23

PLCB3:Ca2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry60
component stoichiometry: Stoichiometry59
component: Protein268
component: SmallMolecule104
xref: UnificationXref940
cellular location: GO:0005829
comment: Reactome DB_ID: 4197704

Exportin complex translocates pre-miRNA to cytosol
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1540
xref: UnificationXref17043
xref: UnificationXref17044
left: Complex821
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex822
right: PhysicalEntity379

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ARG3
data source: Provenance1
name: Q9ARG3
name: TIM23_HUMAN
name: Mitochondrial import inner membrane translocase subunit Tim23
xref: UnificationXref14668
feature: FragmentFeature4316
cellular location: GO:0005743
comment: Reactome DB_ID: 4195097
display name: TIMM23

PLCB2:Ca2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry57
component stoichiometry: Stoichiometry58
component: Protein258
component: SmallMolecule104
xref: UnificationXref929
cellular location: GO:0005829
comment: Reactome DB_ID: 4197703

Removal of miRNA passenger strand
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1541
xref: UnificationXref17114
xref: UnificationXref17113
left: Complex824
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex829

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8VYE2
data source: Provenance1
name: TIM50_HUMAN
name: Mitochondrial import inner membrane translocase subunit TIM50
name: Q8VYE2
xref: UnificationXref14677
feature: FragmentFeature4319
cellular location: GO:0005743
comment: Reactome DB_ID: 4195089
display name: TIMM50

PLCB1:Ca2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry56
component stoichiometry: Stoichiometry55
component: Protein248
component: SmallMolecule104
xref: UnificationXref918
cellular location: GO:0005829
comment: Reactome DB_ID: 4197702

Cleavage-based removal of the siRNA passenger strand by AGO2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1543
xref: UnificationXref17124
xref: UnificationXref17123
left: Complex834
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex835

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LNQ1
data source: Provenance1
name: TIM23_HUMAN
name: Mitochondrial import inner membrane translocase subunit Tim23
name: Q9LNQ1
xref: UnificationXref14670
feature: FragmentFeature4318
cellular location: GO:0005743
comment: Reactome DB_ID: 4195103
display name: TIMM23

PLCbz
type: Complex
data source: Provenance1
member physical entity: PLCB4:Ca2+ (name copied from entity in Homo sapiens)
member physical entity: PLCZ1:Ca2+ (name copied from entity in Homo sapiens)
member physical entity: PLCB1:Ca2+ (name copied from entity in Homo sapiens)
member physical entity: PLCB3:Ca2+ (name copied from entity in Homo sapiens)
member physical entity: PLCB2:Ca2+ (name copied from entity in Homo sapiens)
xref: UnificationXref963
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4197717

methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1529
EC number: 6.1.1.10
xref: UnificationXref16932
xref: UnificationXref16931
left: SmallMolecule1135
left: SmallMolecule22
left: SmallMolecule1136
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule1137
right: SmallMolecule479
right: SmallMolecule440

UnificationXref6096
type: UnificationXref
id: 4177260
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177260

UnificationXref6097
type: UnificationXref
id: REACT_97131
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_97131.9

UnificationXref6098
type: UnificationXref
id: 4192852
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4192852

UnificationXref6099
type: UnificationXref
id: REACT_134492
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_134492.5

A1XJK0
type: Protein
entity reference: A1XJK0
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Mitochondrial import inner membrane translocase subunit Tim22
name: TIM22_HUMAN
xref: UnificationXref14664
feature: FragmentFeature4313
cellular location: GO:0005743
comment: Reactome DB_ID: 4195376
display name: TIMM22

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: A2RVP7
data source: Provenance1
name: Mitochondrial import inner membrane translocase subunit Tim22
name: A2RVP7
name: TIM22_HUMAN
xref: UnificationXref14663
feature: FragmentFeature4312
cellular location: GO:0005743
comment: Reactome DB_ID: 4195375
display name: TIMM22

Homologues of TIMM22
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: A1XJK0
xref: UnificationXref14666
cellular location: GO:0005743
comment: Reactome DB_ID: 4195378
comment: Converted from EntitySet in Reactome

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LNQ1
data source: Provenance1
name: TIM23_HUMAN
name: Mitochondrial import inner membrane translocase subunit Tim23
name: Q9LNQ1
xref: UnificationXref14660
feature: FragmentFeature4311
cellular location: GO:0005758
comment: Reactome DB_ID: 4195279
display name: TIMM23

Cleavage of Target RNAs by Endonucleolytic RISC
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1546
xref: UnificationXref17142
xref: UnificationXref17141
participant stoichiometry: Stoichiometry2473
left: PhysicalEntity384
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity385

Phosphorylation of COP1 at Ser-387 by ATM
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1552
xref: UnificationXref17170
xref: UnificationXref17171
left: SmallMolecule110
left: Protein6481
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule113
right: Protein6487

GOT1 dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry28
component stoichiometry: Stoichiometry27
component: Protein106
component: SmallMolecule44
xref: UnificationXref364
cellular location: GO:0005829
comment: Reactome DB_ID: 4177141

Removal of siRNA passenger strand
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1544
xref: UnificationXref17124
xref: UnificationXref17133
left: Complex836
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex840

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4IAQ1
data source: Provenance1
name: Mitochondrial import inner membrane translocase subunit Tim22
name: F4IAQ1
name: TIM22_HUMAN
xref: UnificationXref14665
feature: FragmentFeature4314
cellular location: GO:0005743
comment: Reactome DB_ID: 4195377
display name: TIMM22

Proteasome mediated degradation of COP1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1555
xref: UnificationXref17184
xref: UnificationXref17183
participant stoichiometry: Stoichiometry2477
left: Complex845
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3409

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4IAQ1
data source: Provenance1
name: Mitochondrial import inner membrane translocase subunit Tim22
name: F4IAQ1
name: TIM22_HUMAN
xref: UnificationXref14651
feature: FragmentFeature4307
cellular location: GO:0005758
comment: Reactome DB_ID: 4195372
display name: TIMM22

FBP1 tetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry30
component stoichiometry: Stoichiometry29
component: Protein114
component: SmallMolecule49
xref: UnificationXref392
cellular location: GO:0005829
comment: Reactome DB_ID: 4176988

MAD2 associates with the Mad1 kinetochore complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1561
xref: UnificationXref17201
xref: UnificationXref17200
left: Protein3898
left: Complex846
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex847

fructose-1,6-bisphosphatase isoforms
type: Complex
data source: Provenance1
member physical entity: FBP2 tetramer (name copied from entity in Homo sapiens)
member physical entity: FBP1 tetramer (name copied from entity in Homo sapiens)
xref: UnificationXref395
cellular location: GO:0005829
display name: FBP tetramer
comment: Reactome DB_ID: 4176991
comment: Converted from EntitySet in Reactome

Translocation of COP1 from the nucleus to the cytoplasm
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1553
xref: UnificationXref17179
xref: UnificationXref17178
left: Protein6487
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein6493

8xUGP2 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry33
component: Protein116
xref: UnificationXref420
cellular location: GO:0005829
comment: Reactome DB_ID: 4176776

Autoubiquitination of phospho-COP1(Ser-387 )
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1554
EC number: 6.3.2.19
xref: UnificationXref17182
xref: UnificationXref17181
participant stoichiometry: Stoichiometry2474
left: Protein6493
left: Protein3409
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex845

FBP2 tetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry32
component stoichiometry: Stoichiometry31
component: SmallMolecule49
component: Protein115
xref: UnificationXref394
cellular location: GO:0005829
comment: Reactome DB_ID: 4176990

p107 (RBL1) binds CyclinE/A:CDK2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1568
xref: UnificationXref17218
xref: UnificationXref17217
left: Complex848
left: Protein6500
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex849

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9S837
data source: Provenance1
name: Q9S837
name: TIM23_HUMAN
name: Mitochondrial import inner membrane translocase subunit Tim23
xref: UnificationXref14658
feature: FragmentFeature4310
cellular location: GO:0005758
comment: Reactome DB_ID: 4195278
display name: TIMM23

PGYB b dimer:AMP (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry36
component stoichiometry: Stoichiometry37
component: Protein119
component: SmallMolecule18
xref: UnificationXref433
cellular location: GO:0005829
comment: Reactome DB_ID: 4192592

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ARG3
data source: Provenance1
name: Q9ARG3
name: TIM23_HUMAN
name: Mitochondrial import inner membrane translocase subunit Tim23
xref: UnificationXref14656
feature: FragmentFeature4309
cellular location: GO:0005758
comment: Reactome DB_ID: 4195277
display name: TIMM23

PGYB dimer b form (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry35
component: Protein119
xref: UnificationXref432
cellular location: GO:0005829
comment: Reactome DB_ID: 4192578

MAD2 converted to an inhibitory state via interaction with Mad1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1562
xref: UnificationXref17202
xref: UnificationXref17203
left: Complex847
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex847

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q38820
data source: Provenance1
name: TIM23_HUMAN
name: Mitochondrial import inner membrane translocase subunit Tim23
name: Q38820
xref: UnificationXref14654
feature: FragmentFeature4308
cellular location: GO:0005758
comment: Reactome DB_ID: 4195276
display name: TIMM23

PGYM b dimer:AMP (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry41
component stoichiometry: Stoichiometry42
component: Protein123
component: SmallMolecule18
xref: UnificationXref443
cellular location: GO:0005829
comment: Reactome DB_ID: 4192587

Release of activated MAD2 from kinetochores
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1563
xref: UnificationXref17204
xref: UnificationXref17205
left: Complex847
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3898
right: Complex846

Homologues of TIMM23
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14661
cellular location: GO:0005758
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4195280

PGYM dimer, b form (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry40
component: Protein123
xref: UnificationXref442
cellular location: GO:0005829
comment: Reactome DB_ID: 4177631

G6PD dimer and tetramer
type: Complex
data source: Provenance1
member physical entity: G6PD dimer (name copied from entity in Homo sapiens)
member physical entity: G6PD tetramer (name copied from entity in Homo sapiens)
xref: UnificationXref490
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4176830

UnificationXref6002
type: UnificationXref
id: 4194252
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4194252

UnificationXref6001
type: UnificationXref
id: 4194250
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4194250

UnificationXref6004
type: UnificationXref
id: CHEBI:15811
db: ChEBI

UnificationXref6003
type: UnificationXref
id: REACT_125894
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_125894.5

UnificationXref6000
type: UnificationXref
id: 4194249
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4194249

UnificationXref6009
type: UnificationXref
id: Q9SHP0
db: UniProt

UnificationXref6006
type: UnificationXref
id: REACT_27529
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_27529.1

UnificationXref6005
type: UnificationXref
id: 936706
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=936706

UnificationXref6008
type: UnificationXref
id: 4194220
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4194220

UnificationXref6007
type: UnificationXref
id: Q96255
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LN27
data source: Provenance1
name: TI17A_HUMAN
name: TIMM17A
name: Mitochondrial import inner membrane translocase subunit Tim17-A
xref: UnificationXref14685
feature: FragmentFeature4323
cellular location: GO:0005743
comment: Reactome DB_ID: 4195116
display name: Q9LN27

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SP35
data source: Provenance1
name: TI17A_HUMAN
name: TIMM17A
name: Mitochondrial import inner membrane translocase subunit Tim17-A
xref: UnificationXref14687
feature: FragmentFeature4324
cellular location: GO:0005743
comment: Reactome DB_ID: 4195120
display name: Q9SP35

Homologues of TIMM17B
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14694
cellular location: GO:0005743
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4195127

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LYG1
data source: Provenance1
name: TIMM17B
name: Mitochondrial import inner membrane translocase subunit Tim17-B
name: TI17B_HUMAN
xref: UnificationXref14689
feature: FragmentFeature4325
cellular location: GO:0005743
comment: Reactome DB_ID: 4195122
display name: Q9LYG1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LAB0
data source: Provenance1
name: TIMM17B
name: Mitochondrial import inner membrane translocase subunit Tim17-B
name: TI17B_HUMAN
xref: UnificationXref14690
feature: FragmentFeature4326
cellular location: GO:0005743
comment: Reactome DB_ID: 4195123
display name: Q8LAB0

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q6S709
data source: Provenance1
name: TIMM17B
name: Mitochondrial import inner membrane translocase subunit Tim17-B
name: TI17B_HUMAN
xref: UnificationXref14691
feature: FragmentFeature4327
cellular location: GO:0005743
comment: Reactome DB_ID: 4195124
display name: Q6S709

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LN27
data source: Provenance1
name: TIMM17B
name: Mitochondrial import inner membrane translocase subunit Tim17-B
name: TI17B_HUMAN
xref: UnificationXref14692
feature: FragmentFeature4328
cellular location: GO:0005743
comment: Reactome DB_ID: 4195125
display name: Q9LN27

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SP35
data source: Provenance1
name: TIMM17B
name: Mitochondrial import inner membrane translocase subunit Tim17-B
name: TI17B_HUMAN
xref: UnificationXref14693
feature: FragmentFeature4329
cellular location: GO:0005743
comment: Reactome DB_ID: 4195126
display name: Q9SP35

Q1G3L1
type: Protein
entity reference: Q1G3L1
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: C18orf55 (TIM21L)
name: TIM21-like protein, mitochondrial
name: TI21L_HUMAN
name: C18orf55
xref: UnificationXref14697
feature: FragmentFeature4330
cellular location: GO:0005743
comment: Reactome DB_ID: 4195132
display name: TIMM21

Homologues of DNAJC19
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14704
cellular location: GO:0005743
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4195145

http://identifiers.org/pubmed/9792662
type: PublicationXref
id: 9792662
author: Morgunov, I
author: Srere, PA
db: Pubmed
title: Interaction between citrate synthase and malate dehydrogenase. Substrate channeling of oxaloacetate
source: J Biol Chem 273:29540-29544
year: 1998

http://identifiers.org/pubmed/11459989
type: PublicationXref
id: 11459989
author: Paulusma, C
author: Wyman, C
author: Kanaar, R
author: Ristic, D
db: Pubmed
title: The architecture of the human Rad54-DNA complex provides evidence for protein translocation along DNA.
source: Proc Natl Acad Sci U S A 98:8454-60
year: 2001

UniProt:B2C6R6
type: ProteinReference
xref: UnificationXref9587
organism: Arabidopsis thaliana

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LYY2
data source: Provenance1
name: Mitochondrial import inner membrane translocase subunit TIM14
name: TIM14_HUMAN
name: DNAJC19
name: DNAJC19 (TIM14) (PAM18)
xref: UnificationXref14703
feature: FragmentFeature4333
cellular location: GO:0005743
comment: Reactome DB_ID: 4195144
display name: Q9LYY2

Homologues of GRPEL1
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14711
cellular location: GO:0005743
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4195181

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8RV04
data source: Provenance1
name: Mitochondrial import inner membrane translocase subunit TIM14
name: TIM14_HUMAN
name: DNAJC19
name: DNAJC19 (TIM14) (PAM18)
xref: UnificationXref14699
feature: FragmentFeature4331
cellular location: GO:0005743
comment: Reactome DB_ID: 4195136
display name: Q8RV04

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SF33
data source: Provenance1
name: Mitochondrial import inner membrane translocase subunit TIM14
name: TIM14_HUMAN
name: DNAJC19
name: DNAJC19 (TIM14) (PAM18)
xref: UnificationXref14701
feature: FragmentFeature4332
cellular location: GO:0005743
comment: Reactome DB_ID: 4195140
display name: Q9SF33

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FLP3
data source: Provenance1
name: GRPE1_HUMAN
name: GrpE protein homolog 1, mitochondrial
name: Q9FLP3
xref: UnificationXref14710
feature: FragmentFeature4336
cellular location: GO:0005743
comment: Reactome DB_ID: 4195180
display name: GRPEL1

Homologues of GRPEL2
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14715
cellular location: GO:0005743
comment: Reactome DB_ID: 4195185
comment: Converted from EntitySet in Reactome

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LB47
data source: Provenance1
name: Q8LB47
name: GRPE1_HUMAN
name: GrpE protein homolog 1, mitochondrial
xref: UnificationXref14706
feature: FragmentFeature4334
cellular location: GO:0005743
comment: Reactome DB_ID: 4195174
display name: GRPEL1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LDE9
data source: Provenance1
name: GRPE1_HUMAN
name: GrpE protein homolog 1, mitochondrial
name: Q8LDE9
xref: UnificationXref14708
feature: FragmentFeature4335
cellular location: GO:0005743
comment: Reactome DB_ID: 4195178
display name: GRPEL1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LB47
data source: Provenance1
name: Q8LB47
name: GRPE2_HUMAN
name: GrpE protein homolog 2, mitochondrial
xref: UnificationXref14712
feature: FragmentFeature4337
cellular location: GO:0005743
comment: Reactome DB_ID: 4195182
display name: GRPEL2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LDE9
data source: Provenance1
name: GRPE2_HUMAN
name: GrpE protein homolog 2, mitochondrial
name: Q8LDE9
xref: UnificationXref14713
feature: FragmentFeature4338
cellular location: GO:0005743
comment: Reactome DB_ID: 4195183
display name: GRPEL2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FLP3
data source: Provenance1
name: GRPE2_HUMAN
name: GrpE protein homolog 2, mitochondrial
name: Q9FLP3
xref: UnificationXref14714
feature: FragmentFeature4339
cellular location: GO:0005743
comment: Reactome DB_ID: 4195184
display name: GRPEL2

Homologues of PAM16
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14733
cellular location: GO:0005743
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4195158

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FLS3
data source: Provenance1
name: TIM16_HUMAN
name: PAM16 (TIM16)
name: Mitochondrial import inner membrane translocase subunit TIM16
name: Q9FLS3
xref: UnificationXref14726
feature: FragmentFeature4343
cellular location: GO:0005743
comment: Reactome DB_ID: 4195149
display name: PAM16

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q93W66
data source: Provenance1
name: TIM16_HUMAN
name: PAM16 (TIM16)
name: Q93W66
name: Mitochondrial import inner membrane translocase subunit TIM16
xref: UnificationXref14728
feature: FragmentFeature4344
cellular location: GO:0005743
comment: Reactome DB_ID: 4195151
display name: PAM16

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LX43
data source: Provenance1
name: TIM16_HUMAN
name: PAM16 (TIM16)
name: Q9LX43
name: Mitochondrial import inner membrane translocase subunit TIM16
xref: UnificationXref14730
feature: FragmentFeature4345
cellular location: GO:0005743
comment: Reactome DB_ID: 4195155
display name: PAM16

Homologues of TIMM44(?-452)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref14723
cellular location: GO:0005743
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4195169

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SIL8
data source: Provenance1
name: TIM44_HUMAN
name: Mitochondrial import inner membrane translocase subunit TIM44
name: TIMM44(?-452)
name: Q9SIL8
xref: UnificationXref14718
feature: FragmentFeature4340
cellular location: GO:0005743
comment: Reactome DB_ID: 4195162
display name: TIMM44

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q1PF33
data source: Provenance1
name: TIM44_HUMAN
name: Mitochondrial import inner membrane translocase subunit TIM44
name: TIMM44(?-452)
name: Q1PF33
xref: UnificationXref14720
feature: FragmentFeature4341
cellular location: GO:0005743
comment: Reactome DB_ID: 4195164
display name: TIMM44

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q5XF06
data source: Provenance1
name: TIM44_HUMAN
name: Mitochondrial import inner membrane translocase subunit TIM44
name: TIMM44(?-452)
name: Q5XF06
xref: UnificationXref14722
feature: FragmentFeature4342
cellular location: GO:0005743
comment: Reactome DB_ID: 4195168
display name: TIMM44

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q93VV9
data source: Provenance1
name: TIM16_HUMAN
name: PAM16 (TIM16)
name: Q93VV9
name: Mitochondrial import inner membrane translocase subunit TIM16
xref: UnificationXref14732
feature: FragmentFeature4346
cellular location: GO:0005743
comment: Reactome DB_ID: 4195157
display name: PAM16

Glucuronidation
type: Pathway
data source: Provenance1
pathway component: REACT 84890.9
evidence: Evidence687
xref: RelationshipXref850
xref: UnificationXref7021
xref: UnificationXref7020
pathway order: PathwayStep684
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Stoichiometry2395
type: Stoichiometry
physical entity: Complex800
stoichiometric coefficient: 1.0

Stoichiometry2394
type: Stoichiometry
physical entity: Complex795
stoichiometric coefficient: 1.0

Stoichiometry2393
type: Stoichiometry
physical entity: Protein2594
stoichiometric coefficient: 1.0

Stoichiometry2392
type: Stoichiometry
physical entity: Protein2515
stoichiometric coefficient: 1.0

Stoichiometry2399
type: Stoichiometry
physical entity: Protein2515
stoichiometric coefficient: 1.0

Stoichiometry2398
type: Stoichiometry
physical entity: Protein2506
stoichiometric coefficient: 1.0

Stoichiometry2397
type: Stoichiometry
physical entity: Protein2489
stoichiometric coefficient: 1.0

Stoichiometry2396
type: Stoichiometry
physical entity: Complex772
stoichiometric coefficient: 1.0

Stoichiometry2390
type: Stoichiometry
physical entity: Complex794
stoichiometric coefficient: 1.0

Stoichiometry2391
type: Stoichiometry
physical entity: Protein2506
stoichiometric coefficient: 1.0

Stoichiometry2389
type: Stoichiometry
physical entity: Complex775
stoichiometric coefficient: 1.0

UnificationXref6049
type: UnificationXref
id: 4177209
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177209

Stoichiometry2385
type: Stoichiometry
physical entity: Complex798
stoichiometric coefficient: 1.0

UnificationXref6045
type: UnificationXref
id: REACT_4034
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4034.2

Stoichiometry2386
type: Stoichiometry
physical entity: Complex796
stoichiometric coefficient: 1.0

UnificationXref6046
type: UnificationXref
id: 508261
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=508261

Stoichiometry2387
type: Stoichiometry
physical entity: Complex797
stoichiometric coefficient: 1.0

UnificationXref6047
type: UnificationXref
id: REACT_21630
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_21630.1

Stoichiometry2388
type: Stoichiometry
physical entity: Protein2489
stoichiometric coefficient: 1.0

UnificationXref6048
type: UnificationXref
id: Q9LDY2
db: UniProt

Stoichiometry2381
type: Stoichiometry
physical entity: Complex799
stoichiometric coefficient: 1.0

UnificationXref6041
type: UnificationXref
id: 70718
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=70718

Stoichiometry2382
type: Stoichiometry
physical entity: PhysicalEntity372
stoichiometric coefficient: 1.0

UnificationXref6042
type: UnificationXref
id: REACT_5465
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5465.1

Stoichiometry2383
type: Stoichiometry
physical entity: Complex776
stoichiometric coefficient: 1.0

UnificationXref6043
type: UnificationXref
id: CHEBI:15479
db: ChEBI

Stoichiometry2384
type: Stoichiometry
physical entity: Complex800
stoichiometric coefficient: 1.0

UnificationXref6044
type: UnificationXref
id: 70851
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=70851

Stoichiometry2380
type: Stoichiometry
physical entity: Complex776
stoichiometric coefficient: 1.0

UnificationXref6040
type: UnificationXref
id: CHEBI:15477
db: ChEBI

SequenceSite5709
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5708
type: SequenceSite
position status: EQUAL
sequence position: 677

SequenceSite5707
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5706
type: SequenceSite
position status: EQUAL
sequence position: 677

SequenceSite5705
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5704
type: SequenceSite
position status: EQUAL
sequence position: 264

SequenceSite5703
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5702
type: SequenceSite
position status: EQUAL
sequence position: 124

SequenceSite5701
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5700
type: SequenceSite
position status: EQUAL
sequence position: 1872

Stoichiometry2378
type: Stoichiometry
physical entity: Complex775
stoichiometric coefficient: 1.0

UnificationXref6038
type: UnificationXref
id: 70715
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=70715

Stoichiometry2379
type: Stoichiometry
physical entity: PhysicalEntity371
stoichiometric coefficient: 1.0

UnificationXref6039
type: UnificationXref
id: REACT_5091
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5091.2

Stoichiometry2376
type: Stoichiometry
physical entity: Complex795
stoichiometric coefficient: 1.0

UnificationXref6036
type: UnificationXref
id: REACT_21879
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_21879.1

Stoichiometry2377
type: Stoichiometry
physical entity: Complex772
stoichiometric coefficient: 1.0

UnificationXref6037
type: UnificationXref
id: CHEBI:15487
db: ChEBI

Stoichiometry2374
type: Stoichiometry
physical entity: Protein2515
stoichiometric coefficient: 1.0

UnificationXref6034
type: UnificationXref
id: REACT_2393
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2393.2

Stoichiometry2375
type: Stoichiometry
physical entity: Protein2594
stoichiometric coefficient: 1.0

UnificationXref6035
type: UnificationXref
id: 508181
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=508181

Stoichiometry2372
type: Stoichiometry
physical entity: Complex794
stoichiometric coefficient: 1.0

UnificationXref6032
type: UnificationXref
id: CHEBI:16530
db: ChEBI

Stoichiometry2373
type: Stoichiometry
physical entity: Protein2506
stoichiometric coefficient: 1.0

UnificationXref6033
type: UnificationXref
id: 113584
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113584

Stoichiometry2370
type: Stoichiometry
physical entity: PhysicalEntity370
stoichiometric coefficient: 1.0

UnificationXref6030
type: UnificationXref
id: 113576
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113576

Stoichiometry2371
type: Stoichiometry
physical entity: Protein2489
stoichiometric coefficient: 1.0

UnificationXref6031
type: UnificationXref
id: REACT_5174
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5174.2

SequenceSite5719
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5718
type: SequenceSite
position status: EQUAL
sequence position: 677

SequenceSite5715
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5714
type: SequenceSite
position status: EQUAL
sequence position: 677

SequenceSite5717
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5716
type: SequenceSite
position status: EQUAL
sequence position: 677

SequenceSite5711
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5710
type: SequenceSite
position status: EQUAL
sequence position: 677

SequenceSite5713
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5712
type: SequenceSite
position status: EQUAL
sequence position: 677

Stoichiometry2367
type: Stoichiometry
physical entity: Protein6296
stoichiometric coefficient: 1.0

UnificationXref6027
type: UnificationXref
id: 113598
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113598

http://identifiers.org/pubmed/20861159
type: PublicationXref
id: 20861159
author: Nilius, B
author: Colsoul, B
author: Gees, M
db: Pubmed
title: The role of transient receptor potential cation channels in Ca2+ signaling
source: Cold Spring Harb Perspect Biol 2:a003962
year: 2010

Stoichiometry2368
type: Stoichiometry
physical entity: PhysicalEntity369
stoichiometric coefficient: 1.0

UnificationXref6028
type: UnificationXref
id: REACT_4718
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4718.2

Stoichiometry2369
type: Stoichiometry
physical entity: Complex776
stoichiometric coefficient: 1.0

UnificationXref6029
type: UnificationXref
id: CHEBI:28654
db: ChEBI

Stoichiometry2360
type: Stoichiometry
physical entity: Protein2598
stoichiometric coefficient: 1.0

UnificationXref6020
type: UnificationXref
id: 4194216
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4194216

Stoichiometry2361
type: Stoichiometry
physical entity: Complex787
stoichiometric coefficient: 1.0

UnificationXref6021
type: UnificationXref
id: REACT_130884
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_130884.5

Stoichiometry2362
type: Stoichiometry
physical entity: Protein6256
stoichiometric coefficient: 1.0

UnificationXref6022
type: UnificationXref
id: 4199917
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199917

Stoichiometry2363
type: Stoichiometry
physical entity: Protein6261
stoichiometric coefficient: 1.0

UnificationXref6023
type: UnificationXref
id: REACT_145534
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_145534.5

Stoichiometry2364
type: Stoichiometry
physical entity: Complex783
stoichiometric coefficient: 1.0

UnificationXref6024
type: UnificationXref
id: 4199403
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199403

Stoichiometry2365
type: Stoichiometry
physical entity: Complex776
stoichiometric coefficient: 1.0

UnificationXref6025
type: UnificationXref
id: REACT_30845
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_30845.10

Stoichiometry2366
type: Stoichiometry
physical entity: Complex785
stoichiometric coefficient: 1.0

UnificationXref6026
type: UnificationXref
id: CHEBI:17865
db: ChEBI

Post-Elongation Processing of Intronless pre-mRNA
type: Pathway
data source: Provenance1
pathway component: REACT 115262.8
evidence: Evidence771
xref: UnificationXref8276
xref: UnificationXref8275
pathway order: PathwayStep765
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Stoichiometry2358
type: Stoichiometry
physical entity: Protein2597
stoichiometric coefficient: 1.0

UnificationXref6018
type: UnificationXref
id: 4194213
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4194213

Stoichiometry2359
type: Stoichiometry
physical entity: Protein6226
stoichiometric coefficient: 1.0

UnificationXref6019
type: UnificationXref
id: 4194214
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4194214

Stoichiometry2356
type: Stoichiometry
physical entity: Protein6221
stoichiometric coefficient: 1.0

UnificationXref6016
type: UnificationXref
id: REACT_141302
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_141302.5

Stoichiometry2357
type: Stoichiometry
physical entity: Protein2585
stoichiometric coefficient: 1.0

UnificationXref6017
type: UnificationXref
id: O82796
db: UniProt

Stoichiometry2350
type: Stoichiometry
physical entity: Protein6152
stoichiometric coefficient: 1.0

UnificationXref6010
type: UnificationXref
id: 4194224
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4194224

Stoichiometry2351
type: Stoichiometry
physical entity: Protein6026
stoichiometric coefficient: 1.0

UnificationXref6011
type: UnificationXref
id: Q0WPU8
db: UniProt

http://identifiers.org/pubmed/17555404
type: PublicationXref
id: 17555404
author: Alp, NJ
author: Schmidt, TS
db: Pubmed
title: Mechanisms for the role of tetrahydrobiopterin in endothelial function and vascular disease
source: Clin Sci (Lond) 113:47-63
year: 2007

Stoichiometry2354
type: Stoichiometry
physical entity: Protein6215
stoichiometric coefficient: 1.0

UnificationXref6014
type: UnificationXref
id: 4194228
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4194228

Stoichiometry2355
type: Stoichiometry
physical entity: Protein6185
stoichiometric coefficient: 1.0

UnificationXref6015
type: UnificationXref
id: 4194230
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4194230

Stoichiometry2352
type: Stoichiometry
physical entity: Protein2573
stoichiometric coefficient: 1.0

UnificationXref6012
type: UnificationXref
id: 4194226
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4194226

Stoichiometry2353
type: Stoichiometry
physical entity: Protein6065
stoichiometric coefficient: 1.0

UnificationXref6013
type: UnificationXref
id: 4194227
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4194227

SequenceSite5747
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5748
type: SequenceSite
position status: EQUAL
sequence position: 1085

SequenceSite5749
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5743
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5744
type: SequenceSite
position status: EQUAL
sequence position: 161

SequenceSite5745
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5746
type: SequenceSite
position status: EQUAL
sequence position: 1085

UnificationXref1872
type: UnificationXref
id: 4184267
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184267

UnificationXref1871
type: UnificationXref
id: Q9M1V2
db: UniProt

UnificationXref1870
type: UnificationXref
id: 4184263
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184263

UnificationXref1876
type: UnificationXref
id: 4184273
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184273

UnificationXref1875
type: UnificationXref
id: Q9STQ6
db: UniProt

UnificationXref1874
type: UnificationXref
id: 4184269
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184269

UnificationXref1873
type: UnificationXref
id: Q0WTI4
db: UniProt

Stoichiometry2344
type: Stoichiometry
physical entity: Protein2515
stoichiometric coefficient: 1.0

UnificationXref1868
type: UnificationXref
id: 4184259
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184259

Stoichiometry2343
type: Stoichiometry
physical entity: PhysicalEntity348
stoichiometric coefficient: 1.0

UnificationXref1869
type: UnificationXref
id: Q9FZ91
db: UniProt

Stoichiometry2342
type: Stoichiometry
physical entity: Protein2489
stoichiometric coefficient: 1.0

UnificationXref1866
type: UnificationXref
id: 4184257
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184257

Stoichiometry2341
type: Stoichiometry
physical entity: Complex413
stoichiometric coefficient: 1.0

UnificationXref1867
type: UnificationXref
id: Q8L5A7
db: UniProt

Stoichiometry2340
type: Stoichiometry
physical entity: Protein6088
stoichiometric coefficient: 1.0

SequenceSite5740
type: SequenceSite
position status: EQUAL
sequence position: 161

SequenceSite5742
type: SequenceSite
position status: EQUAL
sequence position: 161

http://identifiers.org/pubmed/9083049
type: PublicationXref
id: 9083049
author: Lee, PT
author: Shepherd, JA
author: Tzagoloff, A
author: Myles, DC
author: Clarke, CF
author: Shtanko, A
author: Barkovich, RJ
db: Pubmed
title: Characterization of the COQ5 gene from Saccharomyces cerevisiae. Evidence for a C-methyltransferase in ubiquinone biosynthesis
source: J Biol Chem 272:9182-8
year: 1997

Stoichiometry2349
type: Stoichiometry
physical entity: PhysicalEntity349
stoichiometric coefficient: 1.0

SequenceSite5741
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2348
type: Stoichiometry
physical entity: Protein6122
stoichiometric coefficient: 1.0

Stoichiometry2347
type: Stoichiometry
physical entity: Protein2564
stoichiometric coefficient: 1.0

Stoichiometry2346
type: Stoichiometry
physical entity: Protein2534
stoichiometric coefficient: 1.0

Stoichiometry2345
type: Stoichiometry
physical entity: Protein6118
stoichiometric coefficient: 1.0

SequenceSite5758
type: SequenceSite
position status: EQUAL
sequence position: 800

SequenceSite5759
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5756
type: SequenceSite
position status: EQUAL
sequence position: 862

SequenceSite5757
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5754
type: SequenceSite
position status: EQUAL
sequence position: 862

SequenceSite5755
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1861
type: UnificationXref
id: Q9M1V1
db: UniProt

UnificationXref1860
type: UnificationXref
id: 4184247
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184247

UnificationXref1863
type: UnificationXref
id: Q9FL45
db: UniProt

UnificationXref1862
type: UnificationXref
id: 4184251
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184251

UnificationXref1865
type: UnificationXref
id: Q9C9D0
db: UniProt

UnificationXref1864
type: UnificationXref
id: 4184253
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184253

Stoichiometry2331
type: Stoichiometry
physical entity: Protein2576
stoichiometric coefficient: 1.0

UnificationXref1855
type: UnificationXref
id: Q9FZ80
db: UniProt

Stoichiometry2330
type: Stoichiometry
physical entity: Complex775
stoichiometric coefficient: 1.0

UnificationXref1856
type: UnificationXref
id: 4184239
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184239

Stoichiometry2333
type: Stoichiometry
physical entity: PhysicalEntity359
stoichiometric coefficient: 1.0

UnificationXref1857
type: UnificationXref
id: Q9FL46
db: UniProt

Stoichiometry2332
type: Stoichiometry
physical entity: Protein2594
stoichiometric coefficient: 1.0

UnificationXref1858
type: UnificationXref
id: 4184243
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184243

UnificationXref1859
type: UnificationXref
id: Q940P4
db: UniProt

Stoichiometry2339
type: Stoichiometry
physical entity: PhysicalEntity347
stoichiometric coefficient: 1.0

SequenceSite5753
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2338
type: Stoichiometry
physical entity: PhysicalEntity360
stoichiometric coefficient: 1.0

SequenceSite5752
type: SequenceSite
position status: EQUAL
sequence position: 862

SequenceSite5751
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5750
type: SequenceSite
position status: EQUAL
sequence position: 1085

Stoichiometry2335
type: Stoichiometry
physical entity: Complex359
stoichiometric coefficient: 1.0

Stoichiometry2334
type: Stoichiometry
physical entity: Protein2624
stoichiometric coefficient: 1.0

Stoichiometry2337
type: Stoichiometry
physical entity: Complex793
stoichiometric coefficient: 1.0

Stoichiometry2336
type: Stoichiometry
physical entity: PhysicalEntity368
stoichiometric coefficient: 1.0

SequenceSite5721
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5722
type: SequenceSite
position status: EQUAL
sequence position: 677

SequenceSite5723
type: SequenceSite
position status: EQUAL
sequence position: 1

UniProt:F4K4E3
type: ProteinReference
xref: UnificationXref15076
organism: Arabidopsis thaliana

SequenceSite5724
type: SequenceSite
position status: EQUAL
sequence position: 677

SequenceSite5725
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5726
type: SequenceSite
position status: EQUAL
sequence position: 677

SequenceSite5727
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5728
type: SequenceSite
position status: EQUAL
sequence position: 677

UnificationXref1854
type: UnificationXref
id: 4184235
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184235

SequenceSite5729
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1853
type: UnificationXref
id: Q9FX56
db: UniProt

UnificationXref1852
type: UnificationXref
id: 4184233
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184233

UnificationXref1851
type: UnificationXref
id: Q8LEH6
db: UniProt

UnificationXref1850
type: UnificationXref
id: 4184229
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184229

UnificationXref1848
type: UnificationXref
id: 4184225
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184225

UnificationXref1849
type: UnificationXref
id: O82330
db: UniProt

Stoichiometry2322
type: Stoichiometry
physical entity: PhysicalEntity62
stoichiometric coefficient: 1.0

UnificationXref1846
type: UnificationXref
id: REACT_147586
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_147586.5

Stoichiometry2321
type: Stoichiometry
physical entity: PhysicalEntity344
stoichiometric coefficient: 1.0

UnificationXref1847
type: UnificationXref
id: Q9FG94
db: UniProt

Stoichiometry2320
type: Stoichiometry
physical entity: Protein2506
stoichiometric coefficient: 1.0

UnificationXref1844
type: UnificationXref
id: 4197996
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197996

UnificationXref1845
type: UnificationXref
id: 4197997
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197997

Stoichiometry2326
type: Stoichiometry
physical entity: Protein6066
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/12438414
type: PublicationXref
id: 12438414
author: Michael, WM
author: Van Hatten, RA
author: Holway, AH
author: Tutter, AV
author: Khederian, AM
author: Walter, JC
db: Pubmed
title: The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication.
source: J Cell Biol 159:541-7
year: 2002

Stoichiometry2325
type: Stoichiometry
physical entity: Complex362
stoichiometric coefficient: 1.0

Stoichiometry2324
type: Stoichiometry
physical entity: PhysicalEntity345
stoichiometric coefficient: 1.0

Stoichiometry2323
type: Stoichiometry
physical entity: PhysicalEntity353
stoichiometric coefficient: 1.0

Stoichiometry2329
type: Stoichiometry
physical entity: Protein6084
stoichiometric coefficient: 1.0

Stoichiometry2328
type: Stoichiometry
physical entity: Protein6078
stoichiometric coefficient: 2.0

SequenceSite5720
type: SequenceSite
position status: EQUAL
sequence position: 677

Stoichiometry2327
type: Stoichiometry
physical entity: PhysicalEntity355
stoichiometric coefficient: 1.0

Stoichiometry2309
type: Stoichiometry
physical entity: Protein2598
stoichiometric coefficient: 1.0

SequenceSite5734
type: SequenceSite
position status: EQUAL
sequence position: 218

SequenceSite5735
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5732
type: SequenceSite
position status: EQUAL
sequence position: 677

SequenceSite5733
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/9251237
type: PublicationXref
id: 9251237
author: Gallagher, JT
author: Stringer, SE
db: Pubmed
title: Heparan sulphate
source: Int J Biochem Cell Biol 29:709-14
year: 1997

SequenceSite5738
type: SequenceSite
position status: EQUAL
sequence position: 161

SequenceSite5739
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5736
type: SequenceSite
position status: EQUAL
sequence position: 218

SequenceSite5737
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1841
type: UnificationXref
id: 4197993
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197993

UnificationXref1840
type: UnificationXref
id: O82191
db: UniProt

UnificationXref1843
type: UnificationXref
id: 4197995
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197995

UnificationXref1842
type: UnificationXref
id: Q56WI7
db: UniProt

UnificationXref1837
type: UnificationXref
id: 4197987
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197987

UnificationXref1838
type: UnificationXref
id: B9DHM4
db: UniProt

UnificationXref1839
type: UnificationXref
id: 4197989
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197989

UnificationXref1833
type: UnificationXref
id: 4197981
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197981

UnificationXref1834
type: UnificationXref
id: Q56ZP1
db: UniProt

Stoichiometry2311
type: Stoichiometry
physical entity: Protein6256
stoichiometric coefficient: 1.0

UnificationXref1835
type: UnificationXref
id: 4197983
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4197983

Stoichiometry2310
type: Stoichiometry
physical entity: Protein2539
stoichiometric coefficient: 1.0

UnificationXref1836
type: UnificationXref
id: Q9XGZ0
db: UniProt

Stoichiometry2313
type: Stoichiometry
physical entity: Protein6261
stoichiometric coefficient: 1.0

Stoichiometry2312
type: Stoichiometry
physical entity: Protein2554
stoichiometric coefficient: 1.0

Stoichiometry2315
type: Stoichiometry
physical entity: Complex772
stoichiometric coefficient: 1.0

Stoichiometry2314
type: Stoichiometry
physical entity: Complex783
stoichiometric coefficient: 1.0

Stoichiometry2317
type: Stoichiometry
physical entity: Protein6034
stoichiometric coefficient: 1.0

SequenceSite5731
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/19428801
type: PublicationXref
id: 19428801
author: Buddhala, C
author: Wu, Jer-Yuarn
author: Hsu, CC
db: Pubmed
title: A novel mechanism for GABA synthesis and packaging into synaptic vesicles
source: Neurochem Int 55:9-12
year: 2009

Stoichiometry2316
type: Stoichiometry
physical entity: Protein6030
stoichiometric coefficient: 1.0

SequenceSite5730
type: SequenceSite
position status: EQUAL
sequence position: 677

http://identifiers.org/pubmed/11752427
type: PublicationXref
id: 11752427
author: McCarthy, DB
author: Stoops, JK
author: O'Connor, CM
author: Reed, LJ
author: Zhou, ZH
db: Pubmed
title: The remarkable structural and functional organization of the eukaryotic pyruvate dehydrogenase complexes.
source: Proc Natl Acad Sci U S A 98:14802-7
year: 2001

Stoichiometry2319
type: Stoichiometry
physical entity: Protein6064
stoichiometric coefficient: 1.0

Stoichiometry2318
type: Stoichiometry
physical entity: Complex778
stoichiometric coefficient: 1.0

UniProt:F4JSG3
type: ProteinReference
xref: UnificationXref11269
organism: Arabidopsis thaliana

SequenceSite5788
type: SequenceSite
position status: EQUAL
sequence position: 316

http://identifiers.org/pubmed/9593753
type: PublicationXref
id: 9593753
author: Jackowski, S
author: Lykidis, A
author: Murti, KG
db: Pubmed
title: Cloning and characterization of a second human CTP:phosphocholine cytidylyltransferase
source: J Biol Chem 273:14022-9
year: 1998

SequenceSite5787
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5789
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2307
type: Stoichiometry
physical entity: Protein2597
stoichiometric coefficient: 1.0

SequenceSite5783
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2308
type: Stoichiometry
physical entity: Complex787
stoichiometric coefficient: 1.0

SequenceSite5784
type: SequenceSite
position status: EQUAL
sequence position: 316

Stoichiometry2305
type: Stoichiometry
physical entity: Protein6221
stoichiometric coefficient: 1.0

SequenceSite5785
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2306
type: Stoichiometry
physical entity: Protein2585
stoichiometric coefficient: 1.0

SequenceSite5786
type: SequenceSite
position status: EQUAL
sequence position: 316

Stoichiometry2303
type: Stoichiometry
physical entity: Protein6026
stoichiometric coefficient: 1.0

Stoichiometry2304
type: Stoichiometry
physical entity: Protein2573
stoichiometric coefficient: 1.0

SequenceSite5780
type: SequenceSite
position status: EQUAL
sequence position: 316

APC/C-mediated degradation of cell cycle proteins
type: Pathway
data source: Provenance1
pathway component: REACT 107735.9
pathway component: REACT 97346.9
pathway component: REACT 29102.10
pathway component: Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
pathway component: REACT 127989.5
evidence: Evidence1622
xref: UnificationXref17618
xref: UnificationXref17619
xref: RelationshipXref1068
pathway order: PathwayStep1579
pathway order: PathwayStep1587
pathway order: PathwayStep1585
pathway order: PathwayStep1592
pathway order: PathwayStep1595
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Stoichiometry2301
type: Stoichiometry
physical entity: Protein2564
stoichiometric coefficient: 1.0

SequenceSite5781
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2302
type: Stoichiometry
physical entity: PhysicalEntity65
stoichiometric coefficient: 1.0

SequenceSite5782
type: SequenceSite
position status: EQUAL
sequence position: 316

Stoichiometry2300
type: Stoichiometry
physical entity: Protein2534
stoichiometric coefficient: 1.0

SequenceSite5799
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5798
type: SequenceSite
position status: EQUAL
sequence position: 597

SequenceSite5796
type: SequenceSite
position status: EQUAL
sequence position: 316

SequenceSite5797
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5794
type: SequenceSite
position status: EQUAL
sequence position: 316

PublicationXref935
type: PublicationXref
id: 0079130356
author: Shih, VE
author: Chuang, DT
db: ISBN
title: Maple syrup urine disease (branched-chain ketoaciduria)
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 1971-2005
year: 2001

SequenceSite5795
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5792
type: SequenceSite
position status: EQUAL
sequence position: 316

SequenceSite5793
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5790
type: SequenceSite
position status: EQUAL
sequence position: 316

SequenceSite5791
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1899
type: UnificationXref
id: REACT_126260
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_126260.5

Fc epsilon receptor (FCERI) signaling
type: Pathway
data source: Provenance1
pathway component: Autophosphorylation of LYN kinase
pathway component: Role of LAT2/NTAL/LAB on calcium mobilization
pathway component: REACT 168179.1
evidence: Evidence909
xref: UnificationXref10696
xref: RelationshipXref982
xref: UnificationXref10695
pathway order: PathwayStep897
pathway order: PathwayStep899
pathway order: PathwayStep898
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

UnificationXref1897
type: UnificationXref
id: REACT_131067
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_131067.5

UnificationXref1898
type: UnificationXref
id: 4199974
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199974

UnificationXref1895
type: UnificationXref
id: REACT_147071
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_147071.5

UnificationXref1896
type: UnificationXref
id: 4199973
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199973

UnificationXref1893
type: UnificationXref
id: 4184302
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184302

UnificationXref1894
type: UnificationXref
id: 4198000
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4198000

UnificationXref1891
type: UnificationXref
id: P52839
db: UniProt

UnificationXref1892
type: UnificationXref
id: 4184301
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184301

SequenceSite5766
type: SequenceSite
position status: EQUAL
sequence position: 274

UnificationXref1890
type: UnificationXref
id: 4184297
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184297

SequenceSite5765
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5768
type: SequenceSite
position status: EQUAL
sequence position: 274

SequenceSite5767
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5769
type: SequenceSite
position status: EQUAL
sequence position: 275

PublicationXref919
type: PublicationXref
id: 0079130356
author: Simell, O
author: Valle, D
db: ISBN
title: The hyperornithinemias
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 1857-1895
year: 2001

SequenceSite5760
type: SequenceSite
position status: EQUAL
sequence position: 109

SequenceSite5761
type: SequenceSite
position status: EQUAL
sequence position: 1

PublicationXref924
type: PublicationXref
id: 0079130356
author: Phang, JM
author: Hu, CA
author: Valle, D
db: ISBN
title: Disorders of proline and hydroxyproline metabolism
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 1821-1838
year: 2001

SequenceSite5762
type: SequenceSite
position status: EQUAL
sequence position: 274

SequenceSite5763
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5764
type: SequenceSite
position status: EQUAL
sequence position: 274

UnificationXref1889
type: UnificationXref
id: Q8RUC1
db: UniProt

UnificationXref1888
type: UnificationXref
id: 4184293
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184293

UnificationXref1884
type: UnificationXref
id: 4184287
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184287

UnificationXref1885
type: UnificationXref
id: Q8GZ53
db: UniProt

UnificationXref1886
type: UnificationXref
id: 4184289
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184289

UnificationXref1887
type: UnificationXref
id: Q9ZPQ5
db: UniProt

http://identifiers.org/pubmed/9124315
type: PublicationXref
id: 9124315
author: Huang, MY
author: Young, JD
author: Yao, SY
author: Ritzel, MW
author: Elliott, JF
author: Cass, CE
db: Pubmed
title: Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1)
source: Am J Physiol Cell Physiol 272:707-714
year: 1997

UnificationXref1880
type: UnificationXref
id: 4184279
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184279

UnificationXref1881
type: UnificationXref
id: Q9C9C9
db: UniProt

UnificationXref1882
type: UnificationXref
id: 4184283
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184283

UnificationXref1883
type: UnificationXref
id: Q9FX55
db: UniProt

SequenceSite5779
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5778
type: SequenceSite
position status: EQUAL
sequence position: 316

SequenceSite5777
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5776
type: SequenceSite
position status: EQUAL
sequence position: 376

SequenceSite5770
type: SequenceSite
position status: EQUAL
sequence position: 376

SequenceSite5771
type: SequenceSite
position status: EQUAL
sequence position: 275

SequenceSite5774
type: SequenceSite
position status: EQUAL
sequence position: 376

SequenceSite5775
type: SequenceSite
position status: EQUAL
sequence position: 275

SequenceSite5772
type: SequenceSite
position status: EQUAL
sequence position: 376

SequenceSite5773
type: SequenceSite
position status: EQUAL
sequence position: 275

http://identifiers.org/pubmed/8195131
type: PublicationXref
id: 8195131
author: Docherty, AJ
author: Eaton, D
author: Murphy, G
author: Willenbrock, F
author: O'Connell, JP
db: Pubmed
title: Analysis of the role of the COOH-terminal domain in the activation, proteolytic activity, and tissue inhibitor of metalloproteinase interactions of gelatinase B
source: J Biol Chem 269:14967-73
year: 1994

UnificationXref1878
type: UnificationXref
id: 4184277
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184277

UnificationXref1877
type: UnificationXref
id: Q9ZPQ6
db: UniProt

UnificationXref1879
type: UnificationXref
id: Q8RV79
db: UniProt

UnificationXref17057
type: UnificationXref
id: Q9SHF2
db: UniProt

UnificationXref17056
type: UnificationXref
id: 4187421
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187421

UnificationXref17055
type: UnificationXref
id: O04379
db: UniProt

UnificationXref17054
type: UnificationXref
id: 4187420
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187420

3,3',5'-Triiodothyronine
type: SmallMoleculeReference
name: Triiodothyronine, reverse
name: 3,3',5'-Triiodothyronine [ChEBI:28774]
xref: UnificationXref7034

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: B9DGK8
data source: Provenance1
xref: UnificationXref15226
feature: ModificationFeature392
feature: ModificationFeature445
feature: ModificationFeature391
feature: FragmentFeature4557
cellular location: GO:0005829
comment: Reactome DB_ID: 4191834

UnificationXref17059
type: UnificationXref
id: Q9SHF3
db: UniProt

UnificationXref17058
type: UnificationXref
id: 4187422
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187422

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: B5BRC9
data source: Provenance1
xref: UnificationXref15230
feature: ModificationFeature449
feature: ModificationFeature400
feature: ModificationFeature399
feature: FragmentFeature4561
cellular location: GO:0005829
comment: Reactome DB_ID: 4191838

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: F4JV21
data source: Provenance1
xref: UnificationXref15229
feature: ModificationFeature448
feature: ModificationFeature397
feature: FragmentFeature4560
feature: ModificationFeature398
cellular location: GO:0005829
comment: Reactome DB_ID: 4191837

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q94A00
data source: Provenance1
xref: UnificationXref15228
feature: FragmentFeature4559
feature: ModificationFeature396
feature: ModificationFeature447
feature: ModificationFeature395
cellular location: GO:0005829
comment: Reactome DB_ID: 4191836

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: F4K4W6
data source: Provenance1
xref: UnificationXref15227
feature: FragmentFeature4558
feature: ModificationFeature393
feature: ModificationFeature394
feature: ModificationFeature446
cellular location: GO:0005829
comment: Reactome DB_ID: 4191835

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: F4I906
data source: Provenance1
xref: UnificationXref15234
feature: ModificationFeature407
feature: ModificationFeature408
feature: ModificationFeature453
feature: FragmentFeature4565
cellular location: GO:0005829
comment: Reactome DB_ID: 4191842

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q9FM47
data source: Provenance1
xref: UnificationXref15233
feature: FragmentFeature4564
feature: ModificationFeature406
feature: ModificationFeature452
feature: ModificationFeature405
cellular location: GO:0005829
comment: Reactome DB_ID: 4191841

UnificationXref1920
type: UnificationXref
id: 4189078
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189078

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: F4JFN7
data source: Provenance1
xref: UnificationXref15232
feature: ModificationFeature404
feature: ModificationFeature403
feature: FragmentFeature4563
feature: ModificationFeature451
cellular location: GO:0005829
comment: Reactome DB_ID: 4191840

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q9SM01
data source: Provenance1
xref: UnificationXref15231
feature: FragmentFeature4562
feature: ModificationFeature450
feature: ModificationFeature401
feature: ModificationFeature402
cellular location: GO:0005829
comment: Reactome DB_ID: 4191839

UnificationXref1913
type: UnificationXref
id: REACT_17089
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17089.2

UnificationXref1912
type: UnificationXref
id: 389589
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=389589

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q9LHL2
data source: Provenance1
xref: UnificationXref15224
feature: FragmentFeature4555
feature: ModificationFeature387
feature: ModificationFeature443
feature: ModificationFeature388
cellular location: GO:0005829
comment: Reactome DB_ID: 4191832

UnificationXref1911
type: UnificationXref
id: CHEBI:18290
db: ChEBI

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q9FJ56
data source: Provenance1
xref: UnificationXref15225
feature: FragmentFeature4556
feature: ModificationFeature444
feature: ModificationFeature390
feature: ModificationFeature389
cellular location: GO:0005829
comment: Reactome DB_ID: 4191833

UnificationXref1910
type: UnificationXref
id: REACT_17891
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17891.1

UnificationXref1917
type: UnificationXref
id: 4189074
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189074

UnificationXref1916
type: UnificationXref
id: Q9LF46
db: UniProt

UnificationXref1915
type: UnificationXref
id: REACT_17719
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17719.2

UnificationXref1914
type: UnificationXref
id: 191328
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=191328

UnificationXref1919
type: UnificationXref
id: 4189076
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189076

UnificationXref1918
type: UnificationXref
id: 4189075
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189075

UnificationXref17052
type: UnificationXref
id: 4187419
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187419

UnificationXref17053
type: UnificationXref
id: O48771
db: UniProt

UnificationXref17050
type: UnificationXref
id: 4187418
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187418

UnificationXref17051
type: UnificationXref
id: Q9SJK3
db: UniProt

UnificationXref17066
type: UnificationXref
id: 4187426
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187426

http://identifiers.org/pubmed/20147624
type: PublicationXref
id: 20147624
author: Pellegrini-Calace, M
author: Oliva, R
author: Calamita, G
author: Thornton, JM
db: Pubmed
title: Electrostatics of aquaporin and aquaglyceroporin channels correlates with their transport selectivity
source: Proc Natl Acad Sci U S A 107:4135-40
year: 2010

UnificationXref17065
type: UnificationXref
id: Q9XGW1
db: UniProt

UnificationXref17068
type: UnificationXref
id: 4187428
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187428

UnificationXref17067
type: UnificationXref
id: 4187427
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187427

UnificationXref17069
type: UnificationXref
id: 4186912
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186912

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8VZ63
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Q8VZ63
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
xref: UnificationXref15217
feature: ModificationFeature466
feature: FragmentFeature4549
cellular location: GO:0005829
comment: Reactome DB_ID: 4191822
display name: HNRNPD

Q8L779
type: Protein
entity reference: Q8L779
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
xref: UnificationXref15216
feature: ModificationFeature465
feature: FragmentFeature4548
cellular location: GO:0005829
comment: Reactome DB_ID: 4191820
display name: HNRNPD

Q8W555
type: Protein
entity reference: Q8W555
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
xref: UnificationXref15219
feature: ModificationFeature468
feature: FragmentFeature4551
cellular location: GO:0005829
comment: Reactome DB_ID: 4191826
display name: HNRNPD

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O22791
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: O22791
name: HNRPD_HUMAN
xref: UnificationXref15218
feature: FragmentFeature4550
feature: ModificationFeature467
cellular location: GO:0005829
comment: Reactome DB_ID: 4191824
display name: HNRNPD

Homologues of p-S83,S87-Ub-HNRNPD-3
type: Protein
data source: Provenance1
member physical entity: phospho-p-S83,S87-Ub-HNRNPD-3
xref: UnificationXref15251
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4191859

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8W034
data source: Provenance1
name: Ub-HNRNPD-4
name: Q8W034
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
xref: UnificationXref15220
feature: FragmentFeature4552
feature: ModificationFeature469
cellular location: GO:0005829
comment: Reactome DB_ID: 4191828
display name: HNRNPD

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q8W569
data source: Provenance1
xref: UnificationXref15223
feature: ModificationFeature385
feature: ModificationFeature386
feature: ModificationFeature442
feature: FragmentFeature4554
cellular location: GO:0005829
comment: Reactome DB_ID: 4191831

UnificationXref1930
type: UnificationXref
id: CHEBI:16240
db: ChEBI

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q9SFD3
data source: Provenance1
xref: UnificationXref15222
feature: ModificationFeature384
feature: ModificationFeature383
feature: ModificationFeature441
feature: FragmentFeature4553
cellular location: GO:0005829
comment: Reactome DB_ID: 4191830

UnificationXref1931
type: UnificationXref
id: 113575
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113575

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SSE0
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: Q9SSE0
name: HNRPD_HUMAN
xref: UnificationXref15213
feature: FragmentFeature4545
feature: ModificationFeature462
cellular location: GO:0005829
comment: Reactome DB_ID: 4191814
display name: HNRNPD

UnificationXref1922
type: UnificationXref
id: 4199796
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199796

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O23288
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: O23288
name: HNRPD_HUMAN
xref: UnificationXref15214
feature: FragmentFeature4546
feature: ModificationFeature463
cellular location: GO:0005829
comment: Reactome DB_ID: 4191816
display name: HNRNPD

UnificationXref1921
type: UnificationXref
id: REACT_91730
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_91730.9

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4JYK6
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: F4JYK6
name: HNRPD_HUMAN
xref: UnificationXref15215
feature: FragmentFeature4547
feature: ModificationFeature464
cellular location: GO:0005829
comment: Reactome DB_ID: 4191818
display name: HNRNPD

PublicationXref640
type: PublicationXref
id: 0781721458
author: Marks, AL
author: Smith, C
author: Lieberman, M
db: ISBN
title: Pathways of Sugar Metabolism
source: Basic Medical Biochemistry: A Clinical Approach, 2nd ed (Book): 527
year: 2005

UnificationXref1924
type: UnificationXref
id: CHEBI:15379
db: ChEBI

UnificationXref1923
type: UnificationXref
id: REACT_87835
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_87835.9

UnificationXref1926
type: UnificationXref
id: REACT_5022
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5022.2

http://identifiers.org/pubmed/22090471
type: PublicationXref
id: 22090471
author: Jan, Lily Y
author: Huang, Fen
author: Wong, Xiuming
db: Pubmed
title: International Union of Basic and Clinical Pharmacology. LXXXV: calcium-activated chloride channels
source: Pharmacol. Rev. 64:1-15
year: 2012

UnificationXref1925
type: UnificationXref
id: 113535
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113535

UnificationXref1928
type: UnificationXref
id: 389893
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=389893

UnificationXref1927
type: UnificationXref
id: CHEBI:64039
db: ChEBI

http://identifiers.org/pubmed/18481987
type: PublicationXref
id: 18481987
author: Sandler, H
author: Stoecklin, G
db: Pubmed
title: Control of mRNA decay by phosphorylation of tristetraprolin
source: Biochem Soc Trans 36:491-6
year: 2008

UnificationXref1929
type: UnificationXref
id: REACT_17371
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17371.1

UnificationXref17060
type: UnificationXref
id: 4187423
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187423

UnificationXref17061
type: UnificationXref
id: Q9ZVD5
db: UniProt

UnificationXref17062
type: UnificationXref
id: 4187424
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187424

UnificationXref17063
type: UnificationXref
id: Q3E984
db: UniProt

http://identifiers.org/pubmed/10212249
type: PublicationXref
id: 10212249
author: Sondermann, P
author: Steegborn, C
author: Wahl, MC
author: Huber, R
author: Marinkovic, S
author: Jacob, U
author: Worbs, M
author: Clausen, T
db: Pubmed
title: Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration
source: J Biol Chem 274:12675-84
year: 1999

UnificationXref17064
type: UnificationXref
id: 4187425
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187425

UnificationXref17039
type: UnificationXref
id: 4186900
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186900

UnificationXref17038
type: UnificationXref
id: 4186899
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186899

UnificationXref17037
type: UnificationXref
id: 4186898
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186898

UnificationXref17036
type: UnificationXref
id: 4186897
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186897

UnificationXref17035
type: UnificationXref
id: REACT_12796
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_12796.2

UnificationXref17034
type: UnificationXref
id: 203932
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=203932

UnificationXref17033
type: UnificationXref
id: REACT_109723
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_109723.9

UnificationXref17032
type: UnificationXref
id: 4186908
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186908

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SU99
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
name: Q9SU99
xref: UnificationXref15212
feature: FragmentFeature4544
feature: ModificationFeature461
cellular location: GO:0005829
comment: Reactome DB_ID: 4191812
display name: HNRNPD

UnificationXref1941
type: UnificationXref
id: 4184768
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184768

Q949Z3
type: Protein
entity reference: Q949Z3
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
xref: UnificationXref15211
feature: ModificationFeature460
feature: FragmentFeature4543
cellular location: GO:0005829
comment: Reactome DB_ID: 4191810
display name: HNRNPD

UnificationXref1942
type: UnificationXref
id: 4189089
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189089

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8W4A6
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: Q8W4A6
name: HNRPD_HUMAN
xref: UnificationXref15210
feature: FragmentFeature4542
feature: ModificationFeature459
cellular location: GO:0005829
comment: Reactome DB_ID: 4191808
display name: HNRNPD

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9C652
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: Q9C652
name: HNRPD_HUMAN
xref: UnificationXref15209
feature: FragmentFeature4541
feature: ModificationFeature458
cellular location: GO:0005829
comment: Reactome DB_ID: 4191806
display name: HNRNPD

UnificationXref1940
type: UnificationXref
id: REACT_5013
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5013.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WNB9
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: Q0WNB9
name: HNRPD_HUMAN
xref: UnificationXref15208
feature: ModificationFeature457
feature: FragmentFeature4540
cellular location: GO:0005829
comment: Reactome DB_ID: 4191804
display name: HNRNPD

http://identifiers.org/pubmed/12807890
type: PublicationXref
id: 12807890
author: Walker, JE
author: Dionisi-Vici, C
author: Dolce, V
author: Palmieri, F
author: Fiermonte, G
author: David, L
author: Santorelli, FM
db: Pubmed
title: The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms
source: J Biol Chem 278:32778-83
year: 2003

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LDS6
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
name: Q8LDS6
xref: UnificationXref15207
feature: FragmentFeature4539
feature: ModificationFeature456
cellular location: GO:0005829
comment: Reactome DB_ID: 4191802
display name: HNRNPD

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4JYK7
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: F4JYK7
name: HNRPD_HUMAN
xref: UnificationXref15206
feature: FragmentFeature4538
feature: ModificationFeature455
cellular location: GO:0005829
comment: Reactome DB_ID: 4191800
display name: HNRNPD

UnificationXref1939
type: UnificationXref
id: 141335
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=141335

UnificationXref1938
type: UnificationXref
id: 4184767
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184767

UnificationXref1937
type: UnificationXref
id: 4184766
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184766

UnificationXref1936
type: UnificationXref
id: 4184762
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184762

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4I906
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
name: F4I906
xref: UnificationXref15204
feature: FragmentFeature4536
feature: ModificationFeature453
cellular location: GO:0005829
comment: Reactome DB_ID: 4191796
display name: HNRNPD

UnificationXref1935
type: UnificationXref
id: REACT_17125
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17125.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: B9DHV1
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: B9DHV1
name: HNRPD_HUMAN
xref: UnificationXref15205
feature: ModificationFeature454
feature: FragmentFeature4537
cellular location: GO:0005829
comment: Reactome DB_ID: 4191798
display name: HNRNPD

UnificationXref1934
type: UnificationXref
id: 389894
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=389894

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4JFN7
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: F4JFN7
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
xref: UnificationXref15202
feature: FragmentFeature4534
feature: ModificationFeature451
cellular location: GO:0005829
comment: Reactome DB_ID: 4191792
display name: HNRNPD

UnificationXref1933
type: UnificationXref
id: CHEBI:63803
db: ChEBI

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FM47
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: Q9FM47
name: HNRPD_HUMAN
xref: UnificationXref15203
feature: FragmentFeature4535
feature: ModificationFeature452
cellular location: GO:0005829
comment: Reactome DB_ID: 4191794
display name: HNRNPD

UnificationXref1932
type: UnificationXref
id: REACT_2530
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2530.1

UnificationXref17030
type: UnificationXref
id: REACT_12820
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_12820.1

UnificationXref17031
type: UnificationXref
id: 4186896
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186896

Phenyllactate [ChEBI:8100]
type: SmallMoleculeReference
name: Phenyllactate
xref: UnificationXref19658

UnificationXref17048
type: UnificationXref
id: 4187417
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187417

UnificationXref17047
type: UnificationXref
id: Q9C793
db: UniProt

UnificationXref17049
type: UnificationXref
id: Q84VQ0
db: UniProt

UnificationXref17044
type: UnificationXref
id: REACT_91905
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_91905.9

UnificationXref17043
type: UnificationXref
id: 4186905
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186905

UnificationXref17046
type: UnificationXref
id: REACT_12809
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_12809.3

http://identifiers.org/pubmed/12807887
type: PublicationXref
id: 12807887
author: Morgan, A
author: Bernard, SE
author: Shuttleworth, CA
author: Humphries, J
author: Lomas, A
author: Bax, DV
author: Kielty, CM
author: Humphries, MJ
db: Pubmed
title: Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins
source: J Biol Chem 278:34605-16
year: 2003

UnificationXref17045
type: UnificationXref
id: 203896
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=203896

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4JV21
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: F4JV21
name: HNRPD_HUMAN
xref: UnificationXref15199
feature: ModificationFeature448
feature: FragmentFeature4531
cellular location: GO:0005829
comment: Reactome DB_ID: 4191786
display name: HNRNPD

UnificationXref1950
type: UnificationXref
id: 4184755
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184755

Q94A00
type: Protein
entity reference: Q94A00
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
xref: UnificationXref15198
feature: FragmentFeature4530
feature: ModificationFeature447
cellular location: GO:0005829
comment: Reactome DB_ID: 4191784
display name: HNRNPD

UnificationXref1951
type: UnificationXref
id: 4184756
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184756

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SM01
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
name: Q9SM01
xref: UnificationXref15201
feature: ModificationFeature450
feature: FragmentFeature4533
cellular location: GO:0005829
comment: Reactome DB_ID: 4191790
display name: HNRNPD

UnificationXref1952
type: UnificationXref
id: 4189193
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189193

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: B5BRC9
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
name: B5BRC9
xref: UnificationXref15200
feature: ModificationFeature449
feature: FragmentFeature4532
cellular location: GO:0005829
comment: Reactome DB_ID: 4191788
display name: HNRNPD

UnificationXref1953
type: UnificationXref
id: REACT_104352
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_104352.9

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4K4W6
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
name: F4K4W6
xref: UnificationXref15197
feature: FragmentFeature4529
feature: ModificationFeature446
cellular location: GO:0005829
comment: Reactome DB_ID: 4191782
display name: HNRNPD

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: B9DGK8
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: B9DGK8
name: HNRPD_HUMAN
xref: UnificationXref15196
feature: FragmentFeature4528
feature: ModificationFeature445
cellular location: GO:0005829
comment: Reactome DB_ID: 4191780
display name: HNRNPD

Q9FJ56
type: Protein
entity reference: Q9FJ56
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
xref: UnificationXref15195
feature: FragmentFeature4527
feature: ModificationFeature444
cellular location: GO:0005829
comment: Reactome DB_ID: 4191778
display name: HNRNPD

UnificationXref1948
type: UnificationXref
id: REACT_17101
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17101.1

http://identifiers.org/pubmed/16856888
type: PublicationXref
id: 16856888
author: Tomer, A
author: Deutsch, VR
db: Pubmed
title: Megakaryocyte development and platelet production
source: Br J Haematol 134:453-66
year: 2006

UnificationXref1947
type: UnificationXref
id: 389982
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=389982

UnificationXref1949
type: UnificationXref
id: Q8VYI3
db: UniProt

Homologues of Ub-HNRNPD-4
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q949Z3
member physical entity: Q8W555
member physical entity: Q94A00
member physical entity: Q9FJ56
member physical entity: Q8L779
xref: UnificationXref15221
cellular location: GO:0005829
comment: Reactome DB_ID: 4191829
comment: Converted from EntitySet in Reactome

UnificationXref1944
type: UnificationXref
id: 141343
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=141343

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SFD3
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: Q9SFD3
name: HNRPD_HUMAN
xref: UnificationXref15192
feature: FragmentFeature4524
feature: ModificationFeature441
cellular location: GO:0005829
comment: Reactome DB_ID: 4191772
display name: HNRNPD

UnificationXref1943
type: UnificationXref
id: REACT_109682
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_109682.9

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8W569
data source: Provenance1
name: Ub-HNRNPD-4
name: Q8W569
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: HNRPD_HUMAN
xref: UnificationXref15193
feature: FragmentFeature4525
feature: ModificationFeature442
cellular location: GO:0005829
comment: Reactome DB_ID: 4191774
display name: HNRNPD

UnificationXref1946
type: UnificationXref
id: CHEBI:63914
db: ChEBI

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LHL2
data source: Provenance1
name: Ub-HNRNPD-4
name: Heterogeneous nuclear ribonucleoprotein D0
name: Ubiquinated AUF1 isoform p37
name: Q9LHL2
name: HNRPD_HUMAN
xref: UnificationXref15194
feature: FragmentFeature4526
feature: ModificationFeature443
cellular location: GO:0005829
comment: Reactome DB_ID: 4191776
display name: HNRNPD

UnificationXref1945
type: UnificationXref
id: REACT_3341
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3341.1

UnificationXref17040
type: UnificationXref
id: 4186901
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186901

UnificationXref17041
type: UnificationXref
id: 4186902
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186902

UnificationXref17042
type: UnificationXref
id: 4186903
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186903

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q8L779
data source: Provenance1
xref: UnificationXref15177
feature: FragmentFeature4519
feature: ModificationFeature431
feature: ModificationFeature432
cellular location: GO:0005829
comment: Reactome DB_ID: 4191750

UnificationXref17018
type: UnificationXref
id: Q0WP44
db: UniProt

UnificationXref17019
type: UnificationXref
id: 4186895
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186895

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q8W555
data source: Provenance1
xref: UnificationXref15180
feature: ModificationFeature437
feature: ModificationFeature438
feature: FragmentFeature4522
cellular location: GO:0005829
comment: Reactome DB_ID: 4191759

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q8W034
data source: Provenance1
xref: UnificationXref15181
feature: ModificationFeature439
feature: FragmentFeature4523
feature: ModificationFeature440
cellular location: GO:0005829
comment: Reactome DB_ID: 4191762

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q8VZ63
data source: Provenance1
xref: UnificationXref15178
feature: ModificationFeature434
feature: ModificationFeature433
feature: FragmentFeature4520
cellular location: GO:0005829
comment: Reactome DB_ID: 4191753

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: O22791
data source: Provenance1
xref: UnificationXref15179
feature: ModificationFeature436
feature: FragmentFeature4521
feature: ModificationFeature435
cellular location: GO:0005829
comment: Reactome DB_ID: 4191756

UnificationXref17012
type: UnificationXref
id: 4199784
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199784

UnificationXref17013
type: UnificationXref
id: REACT_103575
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_103575.9

UnificationXref17010
type: UnificationXref
id: 4199785
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199785

UnificationXref17011
type: UnificationXref
id: REACT_88111
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_88111.9

UnificationXref17016
type: UnificationXref
id: 4186877
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186877

UnificationXref17017
type: UnificationXref
id: REACT_89539
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_89539.9

UnificationXref17014
type: UnificationXref
id: 203828
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=203828

UnificationXref17015
type: UnificationXref
id: REACT_12806
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_12806.1

http://identifiers.org/pubmed/17380317
type: PublicationXref
id: 17380317
author: Hussain, K
author: Richardson, CC
author: Christie, MR
author: Jones, PM
author: Löbner, K
author: Clark, A
author: Persaud, S
author: Boehm, A
db: Pubmed
title: Low levels of glucose transporters and K+ATP channels in human pancreatic beta cells early in development
source: Diabetologia 50:1000-5
year: 2007

http://identifiers.org/pubmed/9799231
type: PublicationXref
id: 9799231
author: Guillemot, JC
author: Chavrier, P
author: Montcourrier, P
author: Massol, P
db: Pubmed
title: Fc receptor-mediated phagocytosis requires CDC42 and Rac1
source: EMBO J 17:6219-29
year: 1998

http://identifiers.org/pubmed/19010255
type: PublicationXref
id: 19010255
author: Neu-Yilik, G
author: Kulozik, AE
db: Pubmed
title: NMD: multitasking between mRNA surveillance and modulation of gene expression
source: Adv Genet 62:185-243
year: 2008

UnificationXref17029
type: UnificationXref
id: 203866
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=203866

UnificationXref17021
type: UnificationXref
id: 4186881
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186881

cyclopropylamine
type: SmallMoleculeReference
name: cyclopropylamine [ChEBI:34660]
name: Aminocyclopropane
xref: UnificationXref7477

UnificationXref17022
type: UnificationXref
id: P41917
db: UniProt

UnificationXref17023
type: UnificationXref
id: 4186885
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186885

UnificationXref17024
type: UnificationXref
id: P41916
db: UniProt

UnificationXref17025
type: UnificationXref
id: 4186889
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186889

UnificationXref17026
type: UnificationXref
id: 4186890
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186890

UnificationXref17027
type: UnificationXref
id: 4186891
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186891

UnificationXref17028
type: UnificationXref
id: 4186906
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186906

Stoichiometry2603
type: Stoichiometry
physical entity: Protein6676
stoichiometric coefficient: 1.0

Stoichiometry2602
type: Stoichiometry
physical entity: Protein6675
stoichiometric coefficient: 1.0

Stoichiometry2605
type: Stoichiometry
physical entity: Protein6682
stoichiometric coefficient: 1.0

PublicationXref605
type: PublicationXref
id: 9780849387326
author: Clarke, CF
author: Jonassen, T
db: ISBN
title: Genetic Analysis of Coenzyme Q Biosynthesis
source: Coenzyme Q: Molecular Mechanisms in Health and Disease (Book): 185-208
year: 2000

Stoichiometry2604
type: Stoichiometry
physical entity: Protein6681
stoichiometric coefficient: 1.0

Stoichiometry2601
type: Stoichiometry
physical entity: Protein6672
stoichiometric coefficient: 1.0

UnificationXref17020
type: UnificationXref
id: Q8H156
db: UniProt

Stoichiometry2600
type: Stoichiometry
physical entity: Protein6669
stoichiometric coefficient: 1.0

UniProt:P49201
type: ProteinReference
xref: UnificationXref9222
organism: Arabidopsis thaliana

UniProt:P49200
type: ProteinReference
xref: UnificationXref9186
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/12040175
type: PublicationXref
id: 12040175
author: Iyengar, R
author: Ram, PT
author: Neves, SR
db: Pubmed
title: G protein pathways
source: Science 296:1636-9
year: 2002

5-Hydroxytryptamine
type: SmallMoleculeReference
name: 3-(2-Aminoethyl)-1H-indol-5-ol
name: Enteramine
name: 3-(2-Aminoethyl)-1H-indol-5-ol [ChEBI:28790]
name: Serotonin
xref: UnificationXref6512

Stoichiometry2608
type: Stoichiometry
physical entity: Protein6689
stoichiometric coefficient: 1.0

Stoichiometry2609
type: Stoichiometry
physical entity: Protein6692
stoichiometric coefficient: 1.0

UniProt:P49209
type: ProteinReference
xref: UnificationXref8882
organism: Arabidopsis thaliana

Stoichiometry2606
type: Stoichiometry
physical entity: Protein6683
stoichiometric coefficient: 1.0

Stoichiometry2607
type: Stoichiometry
physical entity: Protein6686
stoichiometric coefficient: 1.0

UniProt:P49206
type: ProteinReference
xref: UnificationXref9215
organism: Arabidopsis thaliana

UniProt:P49205
type: ProteinReference
xref: UnificationXref9236
organism: Arabidopsis thaliana

UniProt:P49204
type: ProteinReference
xref: UnificationXref9122
organism: Arabidopsis thaliana

Stoichiometry2612
type: Stoichiometry
physical entity: PhysicalEntity403
stoichiometric coefficient: 1.0

Stoichiometry2611
type: Stoichiometry
physical entity: Protein6696
stoichiometric coefficient: 1.0

Stoichiometry2610
type: Stoichiometry
physical entity: Protein6695
stoichiometric coefficient: 1.0

Stoichiometry2616
type: Stoichiometry
physical entity: Protein6708
stoichiometric coefficient: 1.0

Stoichiometry2615
type: Stoichiometry
physical entity: Protein6705
stoichiometric coefficient: 1.0

Stoichiometry2614
type: Stoichiometry
physical entity: Protein6702
stoichiometric coefficient: 1.0

Stoichiometry2613
type: Stoichiometry
physical entity: Protein6699
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/12032886
type: PublicationXref
id: 12032886
author: Zhou, B
author: Wang, K
author: Gitschier, J
author: Zemansky, J
author: Kuo, YM
db: Pubmed
title: A novel member of a zinc transporter family is defective in acrodermatitis enteropathica
source: Am J Hum Genet 71:66-73
year: 2002

UnificationXref17007
type: UnificationXref
id: 4188729
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188729

UnificationXref17008
type: UnificationXref
id: 4188731
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188731

UnificationXref17009
type: UnificationXref
id: REACT_149904
db: Reactome
id version: 4
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_149904.4

Stoichiometry2617
type: Stoichiometry
physical entity: Protein6711
stoichiometric coefficient: 1.0

UnificationXref17003
type: UnificationXref
id: 379735
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379735

Stoichiometry2618
type: Stoichiometry
physical entity: Protein6714
stoichiometric coefficient: 2.0

UnificationXref17004
type: UnificationXref
id: REACT_15875
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15875.1

Stoichiometry2619
type: Stoichiometry
physical entity: PhysicalEntity404
stoichiometric coefficient: 1.0

UnificationXref17005
type: UnificationXref
id: 379782
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379782

UnificationXref17006
type: UnificationXref
id: REACT_15572
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15572.1

UnificationXref17000
type: UnificationXref
id: REACT_94007
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_94007.9

UnificationXref17001
type: UnificationXref
id: 113540
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113540

UnificationXref17002
type: UnificationXref
id: REACT_2426
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2426.2

Stoichiometry2621
type: Stoichiometry
physical entity: SmallMolecule1156
stoichiometric coefficient: 1.0

Stoichiometry2620
type: Stoichiometry
physical entity: Protein6717
stoichiometric coefficient: 2.0

Stoichiometry2623
type: Stoichiometry
physical entity: Complex882
stoichiometric coefficient: 1.0

Stoichiometry2622
type: Stoichiometry
physical entity: Complex882
stoichiometric coefficient: 1.0

Stoichiometry2625
type: Stoichiometry
physical entity: Complex882
stoichiometric coefficient: 1.0

UnificationXref1907
type: UnificationXref
id: REACT_17536
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17536.2

Stoichiometry2624
type: Stoichiometry
physical entity: SmallMolecule1157
stoichiometric coefficient: 1.0

UnificationXref1908
type: UnificationXref
id: CHEBI:49189
db: ChEBI

Stoichiometry2627
type: Stoichiometry
physical entity: Complex561
stoichiometric coefficient: 1.0

UnificationXref1909
type: UnificationXref
id: 389636
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=389636

Stoichiometry2626
type: Stoichiometry
physical entity: SmallMolecule1158
stoichiometric coefficient: 1.0

UnificationXref1903
type: UnificationXref
id: 389594
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=389594

UnificationXref1904
type: UnificationXref
id: REACT_17914
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17914.2

UnificationXref1905
type: UnificationXref
id: CHEBI:15522
db: ChEBI

UnificationXref1906
type: UnificationXref
id: 389578
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=389578

UnificationXref1900
type: UnificationXref
id: 4199448
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199448

UnificationXref1901
type: UnificationXref
id: REACT_28392
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_28392.10

UnificationXref1902
type: UnificationXref
id: CHEBI:15475
db: ChEBI

Proteasomal clevage of exogenous antigen
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence871
xref: UnificationXref10320
xref: UnificationXref10319
left: PhysicalEntity136
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule879
right: PhysicalEntity124

Translocation of antigenic peptides back to phagosomes via TAP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence869
xref: UnificationXref10313
xref: UnificationXref10314
participant stoichiometry: Stoichiometry1218
participant stoichiometry: Stoichiometry1220
participant stoichiometry: Stoichiometry1219
left: SmallMolecule11
left: SmallMolecule48
left: PhysicalEntity123
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule14
right: PhysicalEntity135
right: SmallMolecule31

MHC class II antigen processing
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence876
EC number: 3.4.22
xref: UnificationXref10402
xref: UnificationXref10401
participant stoichiometry: Stoichiometry1223
left: PhysicalEntity138
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity139

Reduction of disulphide bonds in MHC II antigens
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence875
EC number: 1.8
xref: UnificationXref10356
xref: UnificationXref10357
left: PhysicalEntity137
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity138

UniProt:Q94K13
type: ProteinReference
xref: UnificationXref519
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/7000367
type: PublicationXref
id: 7000367
author: Kozak, M
db: Pubmed
title: Evaluation of the "scanning model" for initiation of protein synthesis in eucaryotes.
source: Cell 22:7-8
year: 1981

http://identifiers.org/pubmed/11912132
type: PublicationXref
id: 11912132
author: Lam, W
author: Jiang, Z
author: Cheng, YC
author: Dutschman, GE
author: Liou, JY
db: Pubmed
title: Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates.
source: Cancer Res 62:1624-31
year: 2002

Association of LBP with LPS
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence879
xref: UnificationXref10421
xref: UnificationXref10420
left: SmallMolecule929
left: Protein3590
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex444

ROS oxidize thioredoxin
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence882
xref: UnificationXref10430
xref: UnificationXref10429
left: Protein1470
left: SmallMolecule930
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein1473

AGER-1,2,3 bind AGEs
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence886
xref: UnificationXref10471
xref: UnificationXref10470
left: Complex445
left: PhysicalEntity141
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex446

DDX41 binds dsDNA or c-di-NMP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence888
xref: UnificationXref10488
xref: UnificationXref10487
left: SmallMolecule935
left: Protein3605
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex447

RNA polymerase III transcribes microbial dsDNA to dsRNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence890
xref: UnificationXref10549
xref: UnificationXref10550
left: PhysicalEntity142
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity144

DHX36 binds DNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence891
xref: UnificationXref10578
xref: UnificationXref10577
left: Protein3653
left: PhysicalEntity149
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex452

Activation of CDC42 by unknown mechanism
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence894
xref: UnificationXref10602
xref: UnificationXref10603
left: Complex453
left: SmallMolecule460
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex454
right: SmallMolecule486

UniProt:Q94K08
type: ProteinReference
xref: UnificationXref3890
organism: Arabidopsis thaliana

Conversion of PA into DAG by PAP-1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence898
EC number: 3.1.3.4
xref: UnificationXref10636
xref: UnificationXref10635
left: SmallMolecule939
left: SmallMolecule48
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule927
right: SmallMolecule31

Hydrolysis of PC to PA by PLD
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence897
EC number: 3.1.4.4
xref: UnificationXref10620
xref: UnificationXref10619
left: SmallMolecule938
left: SmallMolecule48
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule939
right: SmallMolecule940

Active PLCG1 hydrolyses PIP2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence896
EC number: 3.1.4.11
xref: UnificationXref10606
xref: UnificationXref10607
left: SmallMolecule101
left: SmallMolecule48
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule103
right: SmallMolecule927

UniProt:Q94K05
type: ProteinReference
xref: UnificationXref13788
organism: Arabidopsis thaliana

Competitive inhibition of translation initiation by ISGylated 4EHP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence911
xref: UnificationXref10729
xref: UnificationXref10730
left: Complex458
left: Complex455
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex459
right: Complex460

MPG glycosylase mediated recognition and binding of 3-methyladenine
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence917
xref: UnificationXref10746
xref: UnificationXref10747
left: PhysicalEntity156
left: Protein3719
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex461

Production of AA by iPLA2 upon FCGR activation
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence899
EC number: 3
xref: UnificationXref10643
xref: UnificationXref10644
left: SmallMolecule941
left: SmallMolecule48
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule943
right: SmallMolecule942

Autophosphorylation of LYN kinase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence906
EC number: 2.7.10
xref: UnificationXref10689
xref: UnificationXref10690
left: SmallMolecule11
left: Protein3684
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3695
right: SmallMolecule14

MYH glycosylase mediated recognition and binding of an adenine opposite to an 8-oxo guanine
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence920
xref: UnificationXref10764
xref: UnificationXref10763
left: PhysicalEntity159
left: Protein3720
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex464

hOGG1 glycosylase mediated recognition and binding of an 8-oxo guanine opposite to a cytosine
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence921
xref: UnificationXref10773
xref: UnificationXref10774
left: Protein3721
left: PhysicalEntity160
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex465

MPG glycosylase mediated recognition and binding of ethenoadenine
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence918
xref: UnificationXref10752
xref: UnificationXref10751
left: PhysicalEntity157
left: Protein3719
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex462

MPG glycosylase mediated recognition and binding of hypoxanthine
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence919
xref: UnificationXref10756
xref: UnificationXref10757
left: PhysicalEntity158
left: Protein3719
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex463

UniProt:P49211
type: ProteinReference
xref: UnificationXref8827
organism: Arabidopsis thaliana

UniProt:Q94K30
type: ProteinReference
xref: UnificationXref3422
organism: Arabidopsis thaliana

UniProt:Q94K32
type: ProteinReference
xref: UnificationXref295
organism: Arabidopsis thaliana

Signaling by FGFR in disease
type: Pathway
data source: Provenance1
pathway component: REACT 108645.9
pathway component: REACT 140958.5
evidence: Evidence1835
xref: UnificationXref19651
xref: UnificationXref19652
pathway order: PathwayStep1795
pathway order: PathwayStep1147
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction1010
evidence: Evidence1613
xref: UnificationXref17475
xref: UnificationXref17474
xref: RelationshipXref1348
pathway order: PathwayStep1586
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/11427893
type: PublicationXref
id: 11427893
author: Ramaswamy, S
author: Eklund, H
author: Eriksson, S
author: Piskur, J
author: Munch-Petersen, B
author: Johansson, K
author: Knecht, W
author: Ljungcrantz, C
db: Pubmed
title: Structural basis for substrate specificities of cellular deoxyribonucleoside kinases
source: Nat Struct Biol 8:616-620
year: 2001

3-Acetamidopropanal
type: SmallMoleculeReference
name: 3-Acetamidopropanal [ChEBI:30322]
xref: UnificationXref6419

NCBP 20 kDa subunit
type: Protein
entity reference: Q9XFD1
data source: Provenance1
name: 20 kDa nuclear cap binding protein
name: NCBP2
name: Note: the coordinates are copied over from Homo sapiens.
name: NCBP interacting protein 1
name: Q9XFD1
name: CBP20
name: 20 kDa nuclear cap binding protein (NCBP 20 kDa subunit) (CBP20) (NCBP interacting protein 1) (NIP1)
xref: UnificationXref15348
feature: FragmentFeature4605
cellular location: GO:0005829
comment: Reactome DB_ID: 4193790
display name: NIP1

Egress of internalized antigen to the cytosol via sec61
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence867
xref: UnificationXref10302
xref: UnificationXref10301
left: PhysicalEntity132
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity133

http://identifiers.org/pubmed/18395510
type: PublicationXref
id: 18395510
author: Bigotti, MG
author: Clarke, AR
db: Pubmed
title: Chaperonins: The hunt for the Group II mechanism
source: Arch Biochem Biophys 474:331-9
year: 2008

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FJR0
data source: Provenance1
name: Q9FJR0
name: RENT1_HUMAN
name: Regulator of nonsense transcripts 1
xref: UnificationXref15347
feature: FragmentFeature4604
cellular location: GO:0005829
comment: Reactome DB_ID: 4193789
display name: UPF1

Proteasomal cleavage of substrate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence868
xref: UnificationXref10305
xref: UnificationXref10306
left: PhysicalEntity134
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule879
right: Protein3409
right: PhysicalEntity123

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O04425
data source: Provenance1
name: O04425
name: ELAVL1
name: ELAVL1(1-326)
name: ELAV-like protein 1
name: ELAV1_HUMAN
name: HuR (ELAVL1)
xref: UnificationXref15331
feature: FragmentFeature4603
cellular location: GO:0005654
comment: Reactome DB_ID: 4191893
display name: HuR

Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence863
EC number: 3.4.11
xref: UnificationXref10256
xref: UnificationXref10255
left: PhysicalEntity124
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule879
right: PhysicalEntity123

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q6AWW6
data source: Provenance1
name: ELAVL1
name: ELAVL1(1-326)
name: Q6AWW6
name: ELAV-like protein 1
name: ELAV1_HUMAN
name: HuR (ELAVL1)
xref: UnificationXref15330
feature: FragmentFeature4602
cellular location: GO:0005654
comment: Reactome DB_ID: 4191889
display name: HuR

Transport of Antigen peptide in to ER
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence865
xref: UnificationXref10265
xref: UnificationXref10266
participant stoichiometry: Stoichiometry1212
participant stoichiometry: Stoichiometry1211
participant stoichiometry: Stoichiometry1210
left: SmallMolecule11
left: SmallMolecule48
left: PhysicalEntity123
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity131
right: SmallMolecule14
right: SmallMolecule31

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O22905
data source: Provenance1
name: ELAVL1
name: ELAVL1(1-326)
name: ELAV-like protein 1
name: ELAV1_HUMAN
name: O22905
name: HuR (ELAVL1)
xref: UnificationXref15329
feature: FragmentFeature4601
cellular location: GO:0005654
comment: Reactome DB_ID: 4191887
display name: HuR

Polyubiquitination of substrate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence861
EC number: 6.3.2.19
xref: UnificationXref10046
xref: UnificationXref10045
participant stoichiometry: Stoichiometry1163
participant stoichiometry: Stoichiometry1158
left: SmallMolecule11
left: Complex437
left: Complex436
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule53
right: PhysicalEntity119
right: Complex439
right: SmallMolecule18

Homologues of ELAVL1(1-326)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15332
cellular location: GO:0005654
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4191894

Proteasomal cleavage of substrate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence862
xref: UnificationXref10243
xref: UnificationXref10242
left: PhysicalEntity122
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule879
right: Protein3409
right: PhysicalEntity124
right: PhysicalEntity123

early endosome membrane
type: CellularLocationVocabulary
xref: UnificationXref3235

late endosome membrane
type: CellularLocationVocabulary
xref: UnificationXref3296

http://identifiers.org/pubmed/15591024
type: PublicationXref
id: 15591024
author: Takano, K
author: Yoshida, M
author: Asai, M
author: Oiso, Y
author: Itoi, K
author: Yamamori, E
author: Iwasaki, Y
db: Pubmed
title: Calcium/calmodulin kinase IV pathway is involved in the transcriptional regulation of the corticotropin-releasing hormone gene promoter in neuronal cells
source: J Mol Endocrinol 33:639-49
year: 2004

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: B3H5N7
data source: Provenance1
name: Regulator of nonsense transcripts 3A
name: B3H5N7
name: REN3A_HUMAN
xref: UnificationXref15355
feature: FragmentFeature4608
cellular location: GO:0005829
comment: Reactome DB_ID: 4193861
display name: UPF3A

late endosome lumen
type: CellularLocationVocabulary
xref: UnificationXref18915

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FX10
data source: Provenance1
name: Regulator of nonsense transcripts 3A
name: Q9FX10
name: REN3A_HUMAN
xref: UnificationXref15354
feature: FragmentFeature4607
cellular location: GO:0005829
comment: Reactome DB_ID: 4193860
display name: UPF3A

Homologues of UPF3A
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q9FVW4
xref: UnificationXref15357
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4193863

endosome lumen
type: CellularLocationVocabulary
xref: UnificationXref12590

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SIU2
data source: Provenance1
name: 80 kDa nuclear cap binding protein
name: NCBP 80 kDa subunit
name: CBP80
name: Q9SIU2
name: 80 kDa nuclear cap binding protein (NCBP 80 kDa subunit) (CBP80)
xref: UnificationXref15349
feature: FragmentFeature4606
cellular location: GO:0005829
comment: Reactome DB_ID: 4193791
display name: NCBP1

http://identifiers.org/pubmed/8163536
type: PublicationXref
id: 8163536
author: Sidorenko, SP
author: Chandran, KA
author: Clark, EA
author: Disteche, CM
author: Edelhoff, S
author: Law, CL
author: Weiss, A
author: Chan, AC
author: Draves, KE
db: Pubmed
title: Molecular cloning of human Syk. A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex
source: J Biol Chem 269:12310-9
year: 1994

UnificationXref17091
type: UnificationXref
id: 4187440
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187440

UnificationXref17090
type: UnificationXref
id: 4187439
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187439

UnificationXref17093
type: UnificationXref
id: 4187442
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187442

UnificationXref17092
type: UnificationXref
id: 4187441
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187441

UnificationXref17095
type: UnificationXref
id: 4187444
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187444

UniProt:Q94K57
type: ProteinReference
xref: UnificationXref4890
organism: Arabidopsis thaliana

UnificationXref17094
type: UnificationXref
id: 4187443
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187443

UnificationXref17097
type: UnificationXref
id: 4187446
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187446

UnificationXref17096
type: UnificationXref
id: 4187445
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187445

phospho-p-S158,S221-ELAVL1(1-326)
type: Protein
entity reference: O04425
data source: Provenance1
xref: UnificationXref15315
feature: ModificationFeature475
feature: FragmentFeature4597
feature: ModificationFeature474
cellular location: GO:0005654
comment: Reactome DB_ID: 4191922

Homologues of p-S221,S318-ELAVL1(1-326)
type: Protein
data source: Provenance1
member physical entity: phospho-p-S221,S318-ELAVL1(1-326)
xref: UnificationXref15325
cellular location: GO:0005654
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4191916

phospho-p-S221,S318-ELAVL1(1-326)
type: Protein
entity reference: O22905
data source: Provenance1
xref: UnificationXref15322
feature: FragmentFeature4598
feature: ModificationFeature476
feature: ModificationFeature471
cellular location: GO:0005654
comment: Reactome DB_ID: 4191909

phospho-p-S221,S318-ELAVL1(1-326)
type: Protein
entity reference: Q6AWW6
data source: Provenance1
xref: UnificationXref15323
feature: FragmentFeature4599
feature: ModificationFeature473
feature: ModificationFeature477
cellular location: GO:0005654
comment: Reactome DB_ID: 4191912

phospho-p-S221,S318-ELAVL1(1-326)
type: Protein
entity reference: O04425
data source: Provenance1
xref: UnificationXref15324
feature: ModificationFeature475
feature: ModificationFeature478
feature: FragmentFeature4600
cellular location: GO:0005654
comment: Reactome DB_ID: 4191915

Displacement of MYH glycosylase by APE1 at the AP site
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence951
xref: UnificationXref10918
xref: UnificationXref10917
left: Protein3738
left: Complex467
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex478
right: Protein3720

http://identifiers.org/pubmed/15591059
type: PublicationXref
id: 15591059
author: Wang, Y
author: Muallem, S
author: Shcheynikov, N
author: Kim, KH
db: Pubmed
title: SLC26A7 is a Cl- channel regulated by intracellular pH
source: J Biol Chem 280:6463-70
year: 2005

APE1 mediated endonucleolytic cleavage at the 5' side of the base-free deoxyribose residue
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence954
xref: UnificationXref10927
xref: UnificationXref10926
left: Complex478
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex479

Displacement of MPG glycosylase by APE1 at the AP site
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence952
xref: UnificationXref10920
xref: UnificationXref10919
left: Protein3738
left: Complex468
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex478
right: Protein3719

UnificationXref17098
type: UnificationXref
id: 4187447
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187447

Interaction of APE1 with DNA ligase I
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence958
xref: UnificationXref10966
xref: UnificationXref10967
left: Protein3750
left: Protein3738
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex483

UnificationXref17099
type: UnificationXref
id: 4187448
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187448

DNA strand displacement synthesis
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence957
EC number: 2.7.7.7
xref: UnificationXref10959
xref: UnificationXref10958
left: Complex480
left: SmallMolecule952
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex482
right: SmallMolecule535

Interaction between FEN1 and PCNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence960
xref: UnificationXref10979
xref: UnificationXref10980
left: Protein3753
left: Protein3754
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex485

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9T0G5
data source: Provenance1
name: Far upstream element-binding protein 2
name: KHSRP(1-710)
name: Q9T0G5
name: KHSRP
name: FUBP2_HUMAN
xref: UnificationXref15297
feature: FragmentFeature4593
cellular location: GO:0005829
comment: Reactome DB_ID: 4191638
display name: KSRP

Interaction of APE1 with FEN1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence959
xref: UnificationXref10972
xref: UnificationXref10971
left: Protein3753
left: Protein3738
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex484

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WLY0
data source: Provenance1
name: Far upstream element-binding protein 2
name: KHSRP(1-710)
name: Q0WLY0
name: KHSRP
name: FUBP2_HUMAN
xref: UnificationXref15299
feature: FragmentFeature4594
cellular location: GO:0005829
comment: Reactome DB_ID: 4191642
display name: KSRP

Ligation of DNA at sites of patch replacement
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence963
xref: UnificationXref10992
xref: RelationshipXref1004
xref: UnificationXref10991
left: Complex486
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex487

Homologues of p-S158,S221-ELAVL1(1-326)
type: Protein
data source: Provenance1
member physical entity: phospho-p-S158,S221-ELAVL1(1-326)
xref: UnificationXref15316
cellular location: GO:0005654
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4191923

Cleavage of flap structures
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence961
xref: UnificationXref10983
xref: UnificationXref10982
left: Complex482
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity173
right: Complex486

phospho-p-S158,S221-ELAVL1(1-326)
type: Protein
entity reference: O22905
data source: Provenance1
xref: UnificationXref15311
feature: FragmentFeature4595
feature: ModificationFeature470
feature: ModificationFeature471
cellular location: GO:0005654
comment: Reactome DB_ID: 4191918

phospho-p-S158,S221-ELAVL1(1-326)
type: Protein
entity reference: Q6AWW6
data source: Provenance1
xref: UnificationXref15313
feature: ModificationFeature472
feature: ModificationFeature473
feature: FragmentFeature4596
cellular location: GO:0005654
comment: Reactome DB_ID: 4191920

Binding of REV1 to lesioned DNA template
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence967
xref: UnificationXref11018
xref: UnificationXref11019
left: Protein3757
left: PhysicalEntity175
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex488

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8H0U4
data source: Provenance1
name: Q8H0U4
name: Transportin-1
name: Importin beta-2
xref: UnificationXref15285
feature: FragmentFeature4590
cellular location: GO:0005829
comment: Reactome DB_ID: 4191608
display name: TNPO1

Homologues of KHSRP(1-710)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15300
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4191643

Q9ZVW7
type: Protein
entity reference: Q9ZVW7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Transportin-1
name: Importin beta-2
xref: UnificationXref15281
feature: FragmentFeature4588
cellular location: GO:0005829
comment: Reactome DB_ID: 4191604
display name: TNPO1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8H2D6
data source: Provenance1
name: Q8H2D6
name: Transportin-1
name: Importin beta-2
xref: UnificationXref15283
feature: FragmentFeature4589
cellular location: GO:0005829
comment: Reactome DB_ID: 4191606
display name: TNPO1

Insertion of correct bases opposite to the lesion by Pol eta
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence972
EC number: 2.7.7.7
xref: UnificationXref11051
xref: UnificationXref11050
left: Complex490
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex491

Binding of Pol eta to lesioned DNA template
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence971
xref: UnificationXref11046
xref: UnificationXref11045
left: Protein3765
left: PhysicalEntity175
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex490

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O82762
data source: Provenance1
name: Far upstream element-binding protein 2
name: KHSRP(1-710)
name: KHSRP
name: FUBP2_HUMAN
name: O82762
xref: UnificationXref15293
feature: FragmentFeature4591
cellular location: GO:0005829
comment: Reactome DB_ID: 4191632
display name: KSRP

Elongation by REV1 protein
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence969
EC number: 2.7.7.7
xref: UnificationXref11028
xref: UnificationXref11027
left: Complex489
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity177
right: Protein3757

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:F4JLJ3
data source: Provenance1
name: Far upstream element-binding protein 2
name: KHSRP(1-710)
name: F4JLJ3
name: KHSRP
name: FUBP2_HUMAN
xref: UnificationXref15295
feature: FragmentFeature4592
cellular location: GO:0005829
comment: Reactome DB_ID: 4191636
display name: KSRP

Misinsertion of bases opposite to the lesion by HREV1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence968
EC number: 2.7.7.7
xref: UnificationXref11024
xref: UnificationXref11023
left: Complex488
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex489

Elongation by Pol zeta complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence977
EC number: 2.7.7.7
xref: UnificationXref11075
xref: UnificationXref11076
left: Complex493
left: PhysicalEntity179
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex492
right: PhysicalEntity177

Formation of Pol zeta complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence976
xref: UnificationXref11071
xref: UnificationXref11072
left: Protein3777
left: Protein3772
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex492

Binding of Pol zeta to lesioned DNA template
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence975
xref: UnificationXref11069
xref: UnificationXref11070
left: Complex492
left: PhysicalEntity175
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex493

Elongation by Pol eta
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence973
EC number: 2.7.7.7
xref: UnificationXref11053
xref: UnificationXref11052
left: Complex491
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3765
right: PhysicalEntity177

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q1PF58
data source: Provenance1
name: Transportin-1
name: Q1PF58
name: Importin beta-2
xref: UnificationXref15277
feature: FragmentFeature4586
cellular location: GO:0005829
comment: Reactome DB_ID: 4191598
display name: TNPO1

F4ILE2
type: Protein
entity reference: F4ILE2
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Transportin-1
name: Importin beta-2
xref: UnificationXref15279
feature: FragmentFeature4587
cellular location: GO:0005829
comment: Reactome DB_ID: 4191602
display name: TNPO1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9C9F5
data source: Provenance1
name: TTP_HUMAN
name: Q9C9F5
name: Tristetraproline
xref: UnificationXref15272
feature: FragmentFeature4585
cellular location: GO:0005829
comment: Reactome DB_ID: 4191625
display name: ZFP36

Oxidative demethylation of 3-MeC damaged DNA By ABH2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence982
xref: UnificationXref11105
xref: UnificationXref11106
left: SmallMolecule954
left: PhysicalEntity182
left: SmallMolecule953
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity181
right: SmallMolecule956
right: SmallMolecule957
right: SmallMolecule955

Homologues of TNPO1
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q9ZVW7
member physical entity: F4ILE2
xref: UnificationXref15286
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4191609

Oxidative demethylation of 1-MeA damaged DNA By ABH2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence981
xref: UnificationXref11102
xref: UnificationXref11101
left: SmallMolecule954
left: PhysicalEntity180
left: SmallMolecule953
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity181
right: SmallMolecule956
right: SmallMolecule957
right: SmallMolecule955

UnificationXref17073
type: UnificationXref
id: 4186928
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186928

UnificationXref17072
type: UnificationXref
id: 4186924
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186924

UnificationXref17075
type: UnificationXref
id: 4186936
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186936

UnificationXref17074
type: UnificationXref
id: 4186932
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186932

hOGG1 glycosylase mediated recognition and binding of a formamidopyrimidine
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence922
xref: UnificationXref10779
xref: UnificationXref10778
left: Protein3721
left: PhysicalEntity161
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex466

Cleavage 8-oxo guanine by MYH glycosylase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence924
xref: UnificationXref10789
xref: UnificationXref10788
left: Complex464
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex467
right: SmallMolecule944

UnificationXref17071
type: UnificationXref
id: 4186920
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186920

UnificationXref17070
type: UnificationXref
id: 4186916
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186916

UniProt:Q94K73
type: ProteinReference
xref: UnificationXref16938
organism: Arabidopsis thaliana

UniProt:F4K0J5
type: ProteinReference
xref: UnificationXref8264
organism: Arabidopsis thaliana

ZFP36L1
type: Protein
entity reference: Q9C9F5
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Butyrate response factor 1
name: TISB_HUMAN
xref: UnificationXref15264
feature: FragmentFeature4583
cellular location: GO:0005829
comment: Reactome DB_ID: 4191865
display name: Q9C9F5

Homologues of ZFP36
type: Protein
data source: Provenance1
member physical entity: Q9C9N3
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15273
cellular location: GO:0005829
comment: Reactome DB_ID: 4191626
comment: Converted from EntitySet in Reactome

Q9C9N3
type: Protein
entity reference: Q9C9N3
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: TTP_HUMAN
name: Tristetraproline
xref: UnificationXref15271
feature: FragmentFeature4584
cellular location: GO:0005829
comment: Reactome DB_ID: 4191624
display name: ZFP36

Cleavage of 3-methyladenine by MPG glycosylase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence925
xref: UnificationXref10794
xref: UnificationXref10795
left: Complex461
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule945
right: Complex468

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q8W555
data source: Provenance1
xref: UnificationXref15249
feature: FragmentFeature4580
feature: ModificationFeature437
feature: ModificationFeature438
feature: ModificationFeature468
cellular location: GO:0005829
comment: Reactome DB_ID: 4191857

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q8W034
data source: Provenance1
xref: UnificationXref15250
feature: FragmentFeature4581
feature: ModificationFeature439
feature: ModificationFeature440
feature: ModificationFeature469
cellular location: GO:0005829
comment: Reactome DB_ID: 4191858

UniProt:F4K0J3
type: ProteinReference
xref: UnificationXref11908
organism: Arabidopsis thaliana

Homologues of ZFP36L1
type: Protein
data source: Provenance1
member physical entity: ZFP36L1
xref: UnificationXref15265
cellular location: GO:0005829
comment: Reactome DB_ID: 4191866
comment: Converted from EntitySet in Reactome

ZFP36L1
type: Protein
entity reference: Q9C9N3
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Butyrate response factor 1
name: TISB_HUMAN
xref: UnificationXref15262
feature: FragmentFeature4582
cellular location: GO:0005829
comment: Reactome DB_ID: 4191864
display name: Q9C9N3

MBD4 glycosylase mediated recognition and binding of an uracil opposite to a guanine at CpG sequences
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence933
xref: UnificationXref10837
xref: UnificationXref10836
left: Protein3724
left: PhysicalEntity164
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex471

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q8L779
data source: Provenance1
xref: UnificationXref15246
feature: ModificationFeature465
feature: ModificationFeature431
feature: ModificationFeature432
feature: FragmentFeature4577
cellular location: GO:0005829
comment: Reactome DB_ID: 4191854

MBD4 glycosylase mediated recognition and binding of a thymine opposite to a guanine at CpG sequences
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence932
xref: UnificationXref10832
xref: UnificationXref10831
left: Protein3724
left: PhysicalEntity163
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex470

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q8VZ63
data source: Provenance1
xref: UnificationXref15247
feature: ModificationFeature434
feature: ModificationFeature466
feature: ModificationFeature433
feature: FragmentFeature4578
cellular location: GO:0005829
comment: Reactome DB_ID: 4191855

hNTH1 glycosylase mediated recognition and binding of dihydrouracil
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence935
xref: UnificationXref10862
xref: UnificationXref10861
left: Protein3730
left: PhysicalEntity166
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex473

half cystine
type: SequenceModificationVocabulary
xref: UnificationXref5052

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: O22791
data source: Provenance1
xref: UnificationXref15248
feature: ModificationFeature436
feature: ModificationFeature467
feature: ModificationFeature435
feature: FragmentFeature4579
cellular location: GO:0005829
comment: Reactome DB_ID: 4191856

hNTH1 glycosylase mediated recognition and binding of cytosine glycol
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence934
xref: UnificationXref10856
xref: UnificationXref10857
left: Protein3730
left: PhysicalEntity165
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex472

UnificationXref17076
type: UnificationXref
id: 4186940
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186940

Cleavage of hypoxanthine by MPG glycosylase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence927
xref: UnificationXref10804
xref: UnificationXref10803
left: Complex463
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule947
right: Complex468

UnificationXref17077
type: UnificationXref
id: 4186944
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186944

Cleavage of ethenoadenine by MPG glycosylase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence926
xref: UnificationXref10800
xref: UnificationXref10799
left: Complex462
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule946
right: Complex468

UnificationXref17078
type: UnificationXref
id: 4186948
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186948

Cleavage of formamidopyrimidine by hOGG1 glycosylase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence929
EC number: 3.2.2.23
xref: UnificationXref10811
xref: UnificationXref10812
left: Complex466
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex469
right: SmallMolecule948

UnificationXref17079
type: UnificationXref
id: 4186949
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186949

Cleavage of 8-oxo guanine by hOGG1 glycosylase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence928
EC number: 3.2.2.23
xref: UnificationXref10806
xref: UnificationXref10807
left: Complex465
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex469
right: SmallMolecule944

UnificationXref17086
type: UnificationXref
id: 4187435
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187435

UnificationXref17085
type: UnificationXref
id: 4187434
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187434

UnificationXref17084
type: UnificationXref
id: 4187433
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187433

UnificationXref17083
type: UnificationXref
id: 4187432
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187432

UnificationXref17082
type: UnificationXref
id: 4187431
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187431

UnificationXref17081
type: UnificationXref
id: 4187430
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187430

UnificationXref17080
type: UnificationXref
id: 4187429
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187429

hNTH1 glycosylase mediated recognition and binding of formamidopyrimidine
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence936
xref: UnificationXref10865
xref: UnificationXref10864
left: Protein3730
left: PhysicalEntity161
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex474

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: B9DHV1
data source: Provenance1
xref: UnificationXref15235
feature: FragmentFeature4566
feature: ModificationFeature454
feature: ModificationFeature409
feature: ModificationFeature410
cellular location: GO:0005829
comment: Reactome DB_ID: 4191843

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: O23288
data source: Provenance1
xref: UnificationXref15244
feature: FragmentFeature4575
feature: ModificationFeature463
feature: ModificationFeature427
feature: ModificationFeature428
cellular location: GO:0005829
comment: Reactome DB_ID: 4191852

Cleavage of thymine glycol by hNTH1 glycosylase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence939
xref: UnificationXref10876
xref: UnificationXref10877
left: Complex475
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity168
right: Complex476

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: F4JYK6
data source: Provenance1
xref: UnificationXref15245
feature: FragmentFeature4576
feature: ModificationFeature429
feature: ModificationFeature430
feature: ModificationFeature464
cellular location: GO:0005829
comment: Reactome DB_ID: 4191853

hNTH1 glycosylase mediated recognition and binding of thymine glycol
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence937
xref: UnificationXref10870
xref: UnificationXref10869
left: Protein3730
left: PhysicalEntity167
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex475

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q9SU99
data source: Provenance1
xref: UnificationXref15242
feature: ModificationFeature423
feature: FragmentFeature4573
feature: ModificationFeature424
feature: ModificationFeature461
cellular location: GO:0005829
comment: Reactome DB_ID: 4191850

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q9SSE0
data source: Provenance1
xref: UnificationXref15243
feature: ModificationFeature425
feature: ModificationFeature426
feature: FragmentFeature4574
feature: ModificationFeature462
cellular location: GO:0005829
comment: Reactome DB_ID: 4191851

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q8W4A6
data source: Provenance1
xref: UnificationXref15240
feature: ModificationFeature459
feature: ModificationFeature420
feature: ModificationFeature419
feature: FragmentFeature4571
cellular location: GO:0005829
comment: Reactome DB_ID: 4191848

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q949Z3
data source: Provenance1
xref: UnificationXref15241
feature: ModificationFeature422
feature: ModificationFeature460
feature: FragmentFeature4572
feature: ModificationFeature421
cellular location: GO:0005829
comment: Reactome DB_ID: 4191849

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q0WNB9
data source: Provenance1
xref: UnificationXref15238
feature: ModificationFeature415
feature: FragmentFeature4569
feature: ModificationFeature457
feature: ModificationFeature416
cellular location: GO:0005829
comment: Reactome DB_ID: 4191846

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q9C652
data source: Provenance1
xref: UnificationXref15239
feature: FragmentFeature4570
feature: ModificationFeature458
feature: ModificationFeature417
feature: ModificationFeature418
cellular location: GO:0005829
comment: Reactome DB_ID: 4191847

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: F4JYK7
data source: Provenance1
xref: UnificationXref15236
feature: ModificationFeature411
feature: FragmentFeature4567
feature: ModificationFeature412
feature: ModificationFeature455
cellular location: GO:0005829
comment: Reactome DB_ID: 4191844

Displacement of hOGG1 glycosylase by APE1 at the AP site
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence950
xref: UnificationXref10916
xref: UnificationXref10915
left: Complex469
left: Protein3738
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3721
right: Complex478

phospho-p-S83,S87-Ub-HNRNPD-3
type: Protein
entity reference: Q8LDS6
data source: Provenance1
xref: UnificationXref15237
feature: ModificationFeature413
feature: FragmentFeature4568
feature: ModificationFeature414
feature: ModificationFeature456
cellular location: GO:0005829
comment: Reactome DB_ID: 4191845

Displacement of MBD4 glycosylase by APE1 at the AP site
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence949
xref: UnificationXref10913
xref: UnificationXref10914
left: Complex477
left: Protein3738
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3724
right: Complex478

Displacement of hNTH1 glycosylase by APE1 at the AP site
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence948
xref: UnificationXref10912
xref: UnificationXref10911
left: Protein3738
left: Complex476
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex478
right: Protein3730

Cleavage of thymine by MBD4 glycosylase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence944
xref: UnificationXref10896
xref: UnificationXref10895
left: Complex470
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex477
right: SmallMolecule951

UnificationXref17089
type: UnificationXref
id: 4187438
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187438

Cleavage of uracil by MBD4 glycosylase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence943
xref: UnificationXref10892
xref: UnificationXref10891
left: Complex471
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex477
right: SmallMolecule950

Cleavage of formamidopyrimidine by hNTH1 glycosylase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence942
xref: UnificationXref10886
xref: UnificationXref10887
left: Complex474
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex476
right: SmallMolecule948

UnificationXref17087
type: UnificationXref
id: 4187436
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187436

Cleavage of dihydrouracil by hNTH1 glycosylase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence941
xref: UnificationXref10885
xref: UnificationXref10884
left: Complex473
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule949
right: Complex476

UnificationXref17088
type: UnificationXref
id: 4187437
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187437

Cleavage of cytosine glycol by hNTH1 glycosylase
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence940
xref: UnificationXref10881
xref: UnificationXref10880
left: Complex472
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity169
right: Complex476

SequenceSite5801
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5800
type: SequenceSite
position status: EQUAL
sequence position: 597

SequenceSite5805
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5804
type: SequenceSite
position status: EQUAL
sequence position: 597

SequenceSite5803
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5802
type: SequenceSite
position status: EQUAL
sequence position: 597

SequenceSite5809
type: SequenceSite
position status: EQUAL
sequence position: 1970

SequenceSite5808
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5807
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite5806
type: SequenceSite
position status: EQUAL
sequence position: 476

http://identifiers.org/pubmed/17555535
type: PublicationXref
id: 17555535
author: Sherwood, MW
author: Burgoyne, RD
author: Dolman, NJ
author: Haynes, LP
db: Pubmed
title: Specificity, promiscuity and localization of ARF protein interactions with NCS-1 and phosphatidylinositol-4 kinase-III beta
source: Traffic 8:1080-92
year: 2007

SequenceSite5810
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5812
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5811
type: SequenceSite
position status: EQUAL
sequence position: 1720

SequenceSite5814
type: SequenceSite
position status: EQUAL
sequence position: 1

Translocation of ub-FANCD2 and ub-FANCI to chromatin
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1040
xref: UnificationXref11415
xref: UnificationXref11416
left: Complex514
left: PhysicalEntity175
left: Complex515
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex516

SequenceSite5813
type: SequenceSite
position status: EQUAL
sequence position: 1135

SequenceSite5816
type: SequenceSite
position status: EQUAL
sequence position: 1

Ligation of newly synthesized repair patch to incised DNA in TC-NER
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1035
xref: UnificationXref11383
xref: UnificationXref11384
left: Protein3750
left: PhysicalEntity192
left: PhysicalEntity197
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3750
right: PhysicalEntity199

SequenceSite5815
type: SequenceSite
position status: EQUAL
sequence position: 1135

Resumption of transcription after TC-NER
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1037
xref: UnificationXref11388
xref: UnificationXref11389
left: PhysicalEntity199
left: Complex512
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex513

SequenceSite5818
type: SequenceSite
position status: EQUAL
sequence position: 2

3' incision of the lesioned strand of DNA in TC-NER
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1032
xref: UnificationXref11372
xref: UnificationXref11371
left: Complex511
left: PhysicalEntity195
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex511
right: PhysicalEntity196

SequenceSite5817
type: SequenceSite
position status: EQUAL
sequence position: 1135

5' incision leading to excision of DNA fragment with lesion in TC-NER
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1033
xref: UnificationXref11377
xref: UnificationXref11378
left: Complex511
left: PhysicalEntity196
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex511
right: PhysicalEntity198
right: PhysicalEntity197

Assembly of repair proteins at the site of Pol II blockage
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1029
xref: UnificationXref11362
xref: UnificationXref11363
left: Protein3846
left: Protein3834
left: Protein3838
left: Protein3837
left: Complex510
left: Complex393
left: Complex507
left: Protein3839
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex511
right: Complex510

SequenceSite5819
type: SequenceSite
position status: EQUAL
sequence position: 346

Displacement of stalled Pol II from the lesion site
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1031
xref: UnificationXref11368
xref: UnificationXref11367
left: Complex511
left: Complex510
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex511
right: Complex512
right: PhysicalEntity195

Formation of active Pol II complex with lesioned DNA template
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1027
xref: UnificationXref11336
xref: UnificationXref11335
left: PhysicalEntity195
left: Complex421
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex510

RNA Pol II is blocked by the lesion leading to reduced transcription
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1028
xref: UnificationXref11338
xref: RelationshipXref1031
xref: UnificationXref11337
left: Complex510
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex510

Ligation of newly synthesized repair patch to incised DNA in GG-NER
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1024
xref: UnificationXref11326
xref: UnificationXref11327
left: Protein3750
left: PhysicalEntity192
left: PhysicalEntity193
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3750
right: PhysicalEntity194

UniProt:F4JP99
type: ProteinReference
xref: UnificationXref6199
organism: Arabidopsis thaliana

SequenceSite5827
type: SequenceSite
position status: EQUAL
sequence position: 346

Formation of open bubble structure in DNA by helicases
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1018
xref: UnificationXref11299
xref: UnificationXref11300
xref: RelationshipXref1024
left: Complex504
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex506

SequenceSite5826
type: SequenceSite
position status: EQUAL
sequence position: 2

Formation of ERCC1-XPF heterodimeric complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1019
xref: UnificationXref11307
xref: UnificationXref11306
left: Protein3836
left: Protein3835
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex507

SequenceSite5825
type: SequenceSite
position status: EQUAL
sequence position: 346

Binding of ERCC1-XPF to preincision complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1020
xref: UnificationXref11310
xref: UnificationXref11309
xref: RelationshipXref1025
left: Complex507
left: Complex506
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex508

SequenceSite5824
type: SequenceSite
position status: EQUAL
sequence position: 2

3'- incision of DNA by XPG in GG-NER
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1022
xref: UnificationXref11316
xref: RelationshipXref1028
xref: UnificationXref11317
left: Complex508
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex509

SequenceSite5823
type: SequenceSite
position status: EQUAL
sequence position: 346

SequenceSite5822
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite5821
type: SequenceSite
position status: EQUAL
sequence position: 346

SequenceSite5820
type: SequenceSite
position status: EQUAL
sequence position: 2

Association of RAD51 with BRCA2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1002
xref: UnificationXref11196
xref: UnificationXref11195
left: Protein3806
left: Protein3800
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex498

Association of RAD51 with the resected ends of the DNA double-strand break
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1003
xref: UnificationXref11201
xref: UnificationXref11200
left: Protein3806
left: PhysicalEntity184
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex499

Ligation of DNA and formation of Holliday structures following repair synthesis
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1007
xref: UnificationXref11213
xref: UnificationXref11212
left: PhysicalEntity185
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity186

Association of Ku heterodimer with ends of DNA double-strand break
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1012
xref: UnificationXref11230
xref: UnificationXref11231
left: PhysicalEntity187
left: Complex500
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex501

SequenceSite5829
type: SequenceSite
position status: EQUAL
sequence position: 651

XPC binds to HR23B forming a heterodimeric complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1015
xref: UnificationXref11252
xref: UnificationXref11253
left: Protein3810
left: Protein3809
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex502

SequenceSite5828
type: SequenceSite
position status: EQUAL
sequence position: 1

XPC:HR23B complex binds to damaged DNA site with lesion
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1016
xref: UnificationXref11256
xref: UnificationXref11255
left: Complex502
left: PhysicalEntity175
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex503

SequenceSite5836
type: SequenceSite
position status: EQUAL
sequence position: 1

Phosphorylation of MDC1/NFBD1 by ATM (within 2 c-term BRCT domains)
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence994
xref: UnificationXref11160
xref: UnificationXref11159
left: Protein3790
left: SmallMolecule110
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3794
right: SmallMolecule113

SequenceSite5835
type: SequenceSite
position status: EQUAL
sequence position: 651

Formation of RAD50:MRE11 complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence997
xref: UnificationXref11171
xref: UnificationXref11170
left: Protein3798
left: Protein3799
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex496

SequenceSite5838
type: SequenceSite
position status: EQUAL
sequence position: 1

Dissociation of dimeric phospho-ATM complexes
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence992
xref: UnificationXref11134
xref: UnificationXref11133
participant stoichiometry: Stoichiometry1349
left: Complex495
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3781

SequenceSite5837
type: SequenceSite
position status: EQUAL
sequence position: 905

Phosphorylation of NBS1 by ATM
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence993
xref: UnificationXref11146
xref: UnificationXref11147
left: SmallMolecule110
left: Protein3782
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3786
right: SmallMolecule113

SequenceSite5832
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5831
type: SequenceSite
position status: EQUAL
sequence position: 651

SequenceSite5834
type: SequenceSite
position status: EQUAL
sequence position: 1

Association of RAD50:MRE11 complex with NBS1 via MRE11 interaction
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence998
xref: UnificationXref11174
xref: UnificationXref11173
left: Complex496
left: Protein3782
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex497

SequenceSite5833
type: SequenceSite
position status: EQUAL
sequence position: 651

Oxidative demethylation of 1-EtA damaged DNA By ABH2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence983
xref: UnificationXref11112
xref: UnificationXref11111
left: SmallMolecule954
left: PhysicalEntity183
left: SmallMolecule953
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity181
right: SmallMolecule957
right: SmallMolecule955
right: SmallMolecule958

Oxidative demethylation of 1-EtA damaged DNA By ABH3
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence987
xref: UnificationXref11112
xref: UnificationXref11119
left: SmallMolecule954
left: PhysicalEntity183
left: SmallMolecule953
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity181
right: SmallMolecule957
right: SmallMolecule955
right: SmallMolecule958

SequenceSite5839
type: SequenceSite
position status: EQUAL
sequence position: 905

Intermolecular autophosphorylation of ATM within dimeric ATM complexes
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence991
xref: UnificationXref11132
xref: RelationshipXref1017
xref: UnificationXref11131
participant stoichiometry: Stoichiometry1346
participant stoichiometry: Stoichiometry1347
left: SmallMolecule110
left: Complex494
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex495
right: SmallMolecule113

Oxidative demethylation of 1-MeA damaged DNA By ABH3
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence985
xref: UnificationXref11102
xref: UnificationXref11117
left: SmallMolecule954
left: PhysicalEntity180
left: SmallMolecule953
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity181
right: SmallMolecule956
right: SmallMolecule957
right: SmallMolecule955

Oxidative demethylation of 3-MeC damaged DNA By ABH3
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence986
xref: UnificationXref11106
xref: UnificationXref11118
left: SmallMolecule954
left: PhysicalEntity182
left: SmallMolecule953
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity181
right: SmallMolecule956
right: SmallMolecule957
right: SmallMolecule955

SequenceSite5830
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/1703535
type: PublicationXref
id: 1703535
author: Purdue, PE
author: Danpure, CJ
author: Takada, Y
db: Pubmed
title: Identification of mutations associated with peroxisome-to-mitochondrion mistargeting of alanine/glyoxylate aminotransferase in primary hyperoxaluria type 1
source: J Cell Biol 111:2341-51
year: 1990

http://identifiers.org/pubmed/11863375
type: PublicationXref
id: 11863375
author: Yang, RZ
author: Shuldiner, AR
author: Gong, DW
author: Blaileanu, G
author: Hansen, BC
db: Pubmed
title: cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase
source: Genomics 79:445-50
year: 2002

http://identifiers.org/pubmed/11435118
type: PublicationXref
id: 11435118
author: Timm, DE
author: Harris, RA
author: Dorocke, JA
author: Baker, LJ
db: Pubmed
title: The crystal structure of yeast thiamin pyrophosphokinase
source: Structure 9:539-46
year: 2001

http://identifiers.org/pubmed/10783391
type: PublicationXref
id: 10783391
author: Gabel, CA
author: Schulte, GK
author: Hoth, LR
author: Chelvanayagam, G
author: Chrunyk, BA
author: Geoghegan, KF
author: Coggan, M
author: Easteal, S
author: Kamath, AV
author: Board, PG
author: Jermiin, LS
author: Pandit, J
author: Rosner, MH
author: Perregaux, DE
author: Danley, DE
author: Griffor, MC
db: Pubmed
title: Identification, characterization, and crystal structure of the Omega class glutathione transferases
source: J Biol Chem 275:24798-806
year: 2000

http://identifiers.org/pubmed/16543383
type: PublicationXref
id: 16543383
author: Pollard, JW
author: Pollack, SE
author: Cohen, PE
db: Pubmed
title: Genetic analysis of chromosome pairing, recombination, and cell cycle control during first meiotic prophase in mammals
source: Endocr Rev 27:398-426
year: 2006

Stoichiometry2640
type: Stoichiometry
physical entity: Complex890
stoichiometric coefficient: 1.0

Stoichiometry2641
type: Stoichiometry
physical entity: PhysicalEntity224
stoichiometric coefficient: 1.0

Pyridoxine phosphate [ChEBI:8672]
type: SmallMoleculeReference
name: Pyridoxine 5-phosphate
name: Pyridoxine phosphate
name: Pyridoxine 5'-phosphate
xref: UnificationXref5477

Stoichiometry2644
type: Stoichiometry
physical entity: PhysicalEntity225
stoichiometric coefficient: 1.0

Stoichiometry2645
type: Stoichiometry
physical entity: Complex892
stoichiometric coefficient: 1.0

Stoichiometry2642
type: Stoichiometry
physical entity: Complex577
stoichiometric coefficient: 1.0

SequenceSite5880
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2643
type: Stoichiometry
physical entity: SmallMolecule1158
stoichiometric coefficient: 1.0

SequenceSite5881
type: SequenceSite
position status: EQUAL
sequence position: 408

dITP
type: SmallMoleculeReference
name: 2'-Deoxyinosine 5'-triphosphate
name: dITP [ChEBI:10499]
name: 2'-Deoxyinosine-5'-triphosphate
xref: UnificationXref5213

Stoichiometry2648
type: Stoichiometry
physical entity: PhysicalEntity224
stoichiometric coefficient: 1.0

SequenceSite5882
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2649
type: Stoichiometry
physical entity: Complex577
stoichiometric coefficient: 1.0

SequenceSite5883
type: SequenceSite
position status: EQUAL
sequence position: 408

Stoichiometry2646
type: Stoichiometry
physical entity: Complex481
stoichiometric coefficient: 1.0

SequenceSite5884
type: SequenceSite
position status: EQUAL
sequence position: 771

2'-Deoxyinosine 5'-phosphate [ChEBI:28806]
type: SmallMoleculeReference
name: 2'-Deoxyinosine 5'-phosphate
name: dIMP
xref: UnificationXref4635

Stoichiometry2647
type: Stoichiometry
physical entity: Complex481
stoichiometric coefficient: 1.0

SequenceSite5885
type: SequenceSite
position status: EQUAL
sequence position: 783

SequenceSite5887
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5886
type: SequenceSite
position status: EQUAL
sequence position: 1254

SequenceSite5889
type: SequenceSite
position status: EQUAL
sequence position: 771

Stoichiometry2639
type: Stoichiometry
physical entity: Complex577
stoichiometric coefficient: 1.0

SequenceSite5888
type: SequenceSite
position status: EQUAL
sequence position: 1290

http://identifiers.org/pubmed/11278778
type: PublicationXref
id: 11278778
author: Trimble, RB
author: Cipollo, JF
author: Yan, Q
author: Dean, N
author: Chi, JH
db: Pubmed
title: The yeast ALG11 gene specifies addition of the terminal alpha 1,2-Man to the Man5GlcNAc2-PP-dolichol N-glycosylation intermediate formed on the cytosolic side of the endoplasmic reticulum
source: J Biol Chem 276:21828-40
year: 2001

UnificationXref1999
type: UnificationXref
id: REACT_17869
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17869.1

UnificationXref1998
type: UnificationXref
id: 390248
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=390248

Stoichiometry2630
type: Stoichiometry
physical entity: PhysicalEntity224
stoichiometric coefficient: 1.0

Stoichiometry2631
type: Stoichiometry
physical entity: SmallMolecule1158
stoichiometric coefficient: 1.0

SequenceSite5891
type: SequenceSite
position status: EQUAL
sequence position: 1254

Stoichiometry2632
type: Stoichiometry
physical entity: Complex562
stoichiometric coefficient: 1.0

SequenceSite5892
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2633
type: Stoichiometry
physical entity: Complex888
stoichiometric coefficient: 1.0

Stoichiometry2634
type: Stoichiometry
physical entity: PhysicalEntity225
stoichiometric coefficient: 1.0

SequenceSite5890
type: SequenceSite
position status: EQUAL
sequence position: 783

Stoichiometry2635
type: Stoichiometry
physical entity: PhysicalEntity224
stoichiometric coefficient: 1.0

SequenceSite5895
type: SequenceSite
position status: EQUAL
sequence position: 783

Stoichiometry2636
type: Stoichiometry
physical entity: Complex575
stoichiometric coefficient: 1.0

SequenceSite5896
type: SequenceSite
position status: EQUAL
sequence position: 1254

Stoichiometry2637
type: Stoichiometry
physical entity: SmallMolecule1158
stoichiometric coefficient: 1.0

SequenceSite5893
type: SequenceSite
position status: EQUAL
sequence position: 1290

Stoichiometry2638
type: Stoichiometry
physical entity: PhysicalEntity225
stoichiometric coefficient: 1.0

SequenceSite5894
type: SequenceSite
position status: EQUAL
sequence position: 771

Stoichiometry2629
type: Stoichiometry
physical entity: Complex562
stoichiometric coefficient: 1.0

Stoichiometry2628
type: Stoichiometry
physical entity: Complex887
stoichiometric coefficient: 1.0

SequenceSite5899
type: SequenceSite
position status: EQUAL
sequence position: 771

SequenceSite5898
type: SequenceSite
position status: EQUAL
sequence position: 1290

SequenceSite5897
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/10903473
type: PublicationXref
id: 10903473
author: Sprecher, H
db: Pubmed
title: Metabolism of highly unsaturated n-3 and n-6 fatty acids
source: Biochim Biophys Acta 1486:219-31
year: 2000

Stoichiometry2662
type: Stoichiometry
physical entity: Complex481
stoichiometric coefficient: 1.0

Stoichiometry2663
type: Stoichiometry
physical entity: Complex577
stoichiometric coefficient: 1.0

Stoichiometry2660
type: Stoichiometry
physical entity: Complex896
stoichiometric coefficient: 1.0

Stoichiometry2661
type: Stoichiometry
physical entity: PhysicalEntity232
stoichiometric coefficient: 1.0

Stoichiometry2668
type: Stoichiometry
physical entity: Complex577
stoichiometric coefficient: 1.0

Stoichiometry2669
type: Stoichiometry
physical entity: SmallMolecule1158
stoichiometric coefficient: 1.0

Stoichiometry2666
type: Stoichiometry
physical entity: PhysicalEntity406
stoichiometric coefficient: 1.0

Stoichiometry2667
type: Stoichiometry
physical entity: Complex481
stoichiometric coefficient: 1.0

Stoichiometry2664
type: Stoichiometry
physical entity: PhysicalEntity405
stoichiometric coefficient: 1.0

Stoichiometry2665
type: Stoichiometry
physical entity: SmallMolecule1158
stoichiometric coefficient: 1.0

Stoichiometry2650
type: Stoichiometry
physical entity: PhysicalEntity405
stoichiometric coefficient: 1.0

Stoichiometry2651
type: Stoichiometry
physical entity: SmallMolecule1158
stoichiometric coefficient: 1.0

Stoichiometry2652
type: Stoichiometry
physical entity: Complex481
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/1968462
type: PublicationXref
id: 1968462
author: Edwards, PA
author: Kutsunai, SY
author: Wilkin, DJ
db: Pubmed
title: Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and 3-hydroxy-3-methylglutaryl coenzyme A synthase by phorbol ester
source: J Biol Chem 265:4607-14
year: 1990

Stoichiometry2657
type: Stoichiometry
physical entity: Complex505
stoichiometric coefficient: 1.0

Stoichiometry2658
type: Stoichiometry
physical entity: Complex895
stoichiometric coefficient: 1.0

Stoichiometry2659
type: Stoichiometry
physical entity: Protein4310
stoichiometric coefficient: 1.0

Stoichiometry2653
type: Stoichiometry
physical entity: Complex577
stoichiometric coefficient: 1.0

Stoichiometry2654
type: Stoichiometry
physical entity: PhysicalEntity405
stoichiometric coefficient: 1.0

Stoichiometry2655
type: Stoichiometry
physical entity: SmallMolecule1158
stoichiometric coefficient: 1.0

Stoichiometry2656
type: Stoichiometry
physical entity: PhysicalEntity173
stoichiometric coefficient: 1.0

Stoichiometry2689
type: Stoichiometry
physical entity: SmallMolecule285
stoichiometric coefficient: 4.0

Stoichiometry2688
type: Stoichiometry
physical entity: SmallMolecule973
stoichiometric coefficient: 3.0

dCDP
type: SmallMoleculeReference
name: dCDP [ChEBI:28846]
name: 2'-Deoxycytidine diphosphate
name: 2'-Deoxycytidine 5'-diphosphate
xref: UnificationXref4993

Stoichiometry2687
type: Stoichiometry
physical entity: SmallMolecule37
stoichiometric coefficient: 3.0

Stoichiometry2686
type: Stoichiometry
physical entity: SmallMolecule1260
stoichiometric coefficient: 2.0

SequenceSite5841
type: SequenceSite
position status: EQUAL
sequence position: 534

SequenceSite5840
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2681
type: Stoichiometry
physical entity: Protein6932
stoichiometric coefficient: 2.0

Stoichiometry2680
type: Stoichiometry
physical entity: Protein6931
stoichiometric coefficient: 2.0

UnificationXref1969
type: UnificationXref
id: CHEBI:15366
db: ChEBI

Stoichiometry2685
type: Stoichiometry
physical entity: Protein7212
stoichiometric coefficient: 1.0

UnificationXref1967
type: UnificationXref
id: 193514
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=193514

Stoichiometry2684
type: Stoichiometry
physical entity: Protein7201
stoichiometric coefficient: 4.0

UnificationXref1968
type: UnificationXref
id: REACT_10138
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_10138.1

Stoichiometry2683
type: Stoichiometry
physical entity: SmallMolecule1198
stoichiometric coefficient: 2.0

UnificationXref1965
type: UnificationXref
id: 353123
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=353123

Stoichiometry2682
type: Stoichiometry
physical entity: SmallMolecule37
stoichiometric coefficient: 2.0

UnificationXref1966
type: UnificationXref
id: REACT_17437
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17437.2

UnificationXref1975
type: UnificationXref
id: 4184796
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184796

UnificationXref1974
type: UnificationXref
id: B3H5Z2
db: UniProt

UnificationXref1973
type: UnificationXref
id: 4184792
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184792

UnificationXref1972
type: UnificationXref
id: Q56XD4
db: UniProt

UnificationXref1971
type: UnificationXref
id: REACT_17568
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17568.2

UnificationXref1970
type: UnificationXref
id: 390305
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=390305

SequenceSite5842
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5843
type: SequenceSite
position status: EQUAL
sequence position: 534

SequenceSite5844
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5845
type: SequenceSite
position status: EQUAL
sequence position: 316

5'-Phosphoribosyl-5-aminoimidazole [ChEBI:28843]
type: SmallMoleculeReference
name: 5'-Phosphoribosyl-5-aminoimidazole
name: Aminoimidazole ribotide
name: 1-(5'-Phosphoribosyl)-5-aminoimidazole
name: 1-(5-Phospho-D-ribosyl)-5-aminoimidazole
name: AIR
xref: UnificationXref4525

SequenceSite5846
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5847
type: SequenceSite
position status: EQUAL
sequence position: 316

SequenceSite5848
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/10092647
type: PublicationXref
id: 10092647
author: Wang, X
author: Nowatzke, W
author: Ramanadham, S
author: Ma, Z
author: Turk, J
db: Pubmed
title: Human pancreatic islets express mRNA species encoding two distinct catalytically active isoforms of group VI phospholipase A2 (iPLA2) that arise from an exon-skipping mechanism of alternative splicing of the transcript from the iPLA2 gene on chromosome 22q13.1
source: J Biol Chem 274:9607-16
year: 1999

SequenceSite5849
type: SequenceSite
position status: EQUAL
sequence position: 1390

Stoichiometry2676
type: Stoichiometry
physical entity: SmallMolecule631
stoichiometric coefficient: 2.0

http://identifiers.org/pubmed/17170135
type: PublicationXref
id: 17170135
author: Li, JL
author: Gimeno, RE
author: Li, D
author: Tobin, JF
author: Cao, J
db: Pubmed
title: Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis
source: Proc Natl Acad Sci U S A 103:19695-700
year: 2006

Stoichiometry2675
type: Stoichiometry
physical entity: SmallMolecule1158
stoichiometric coefficient: 1.0

Stoichiometry2678
type: Stoichiometry
physical entity: SmallMolecule631
stoichiometric coefficient: 3.0

Stoichiometry2677
type: Stoichiometry
physical entity: SmallMolecule634
stoichiometric coefficient: 2.0

SequenceSite5852
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2679
type: Stoichiometry
physical entity: SmallMolecule634
stoichiometric coefficient: 3.0

SequenceSite5851
type: SequenceSite
position status: EQUAL
sequence position: 1390

SequenceSite5850
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref1958
type: UnificationXref
id: CHEBI:15371
db: ChEBI

UnificationXref1959
type: UnificationXref
id: 389996
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=389996

Stoichiometry2670
type: Stoichiometry
physical entity: PhysicalEntity407
stoichiometric coefficient: 1.0

Stoichiometry2672
type: Stoichiometry
physical entity: Complex577
stoichiometric coefficient: 1.0

UnificationXref1954
type: UnificationXref
id: 192307
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=192307

Stoichiometry2671
type: Stoichiometry
physical entity: Complex481
stoichiometric coefficient: 1.0

UnificationXref1955
type: UnificationXref
id: REACT_10489
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_10489.1

Stoichiometry2674
type: Stoichiometry
physical entity: PhysicalEntity407
stoichiometric coefficient: 1.0

UnificationXref1956
type: UnificationXref
id: 193465
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=193465

Stoichiometry2673
type: Stoichiometry
physical entity: SmallMolecule1158
stoichiometric coefficient: 1.0

UnificationXref1957
type: UnificationXref
id: REACT_10257
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_10257.1

UnificationXref1962
type: UnificationXref
id: REACT_10230
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_10230.1

UnificationXref1961
type: UnificationXref
id: 192305
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=192305

UnificationXref1964
type: UnificationXref
id: REACT_109984
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_109984.9

UnificationXref1963
type: UnificationXref
id: 4189194
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189194

UnificationXref1960
type: UnificationXref
id: REACT_18106
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_18106.1

http://identifiers.org/pubmed/10371034
type: PublicationXref
id: 10371034
author: Rüegsegger, U
author: Wahle, E
db: Pubmed
title: 3'-End processing of pre-mRNA in eukaryotes.
source: FEMS Microbiol Rev 23:277-95
year: 1999

http://identifiers.org/pubmed/8567683
type: PublicationXref
id: 8567683
author: Beardsley, GP
author: Moroson, BA
author: Rayl, EA
db: Pubmed
title: The human purH gene product, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
source: J Biol Chem 271:2225-2233
year: 1996

SequenceSite5855
type: SequenceSite
position status: EQUAL
sequence position: 108

SequenceSite5856
type: SequenceSite
position status: EQUAL
sequence position: 1

dUDP [ChEBI:28850]
type: SmallMoleculeReference
name: 2'-Deoxyuridine 5'-diphosphate
name: dUDP
xref: UnificationXref5021

SequenceSite5853
type: SequenceSite
position status: EQUAL
sequence position: 1390

SequenceSite5854
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5859
type: SequenceSite
position status: EQUAL
sequence position: 108

SequenceSite5857
type: SequenceSite
position status: EQUAL
sequence position: 108

SequenceSite5858
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5861
type: SequenceSite
position status: EQUAL
sequence position: 204

SequenceSite5860
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5863
type: SequenceSite
position status: EQUAL
sequence position: 204

SequenceSite5862
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/14671330
type: PublicationXref
id: 14671330
author: McRee, DE
author: Ribas de Pouplana, L
author: Otero, FJ
author: Yang, XL
author: Schimmel, P
author: Skene, RJ
db: Pubmed
title: Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
source: Proc Natl Acad Sci U S A 100:15376-80
year: 2003

UnificationXref1989
type: UnificationXref
id: REACT_17913
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17913.2

UnificationXref1987
type: UnificationXref
id: CHEBI:52966
db: ChEBI

UnificationXref1988
type: UnificationXref
id: 390260
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=390260

UnificationXref1993
type: UnificationXref
id: 4189215
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189215

UnificationXref1992
type: UnificationXref
id: REACT_18221
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_18221.1

UnificationXref1991
type: UnificationXref
id: 390249
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=390249

UnificationXref1990
type: UnificationXref
id: CHEBI:52975
db: ChEBI

UnificationXref1997
type: UnificationXref
id: CHEBI:64972
db: ChEBI

UnificationXref1996
type: UnificationXref
id: REACT_97066
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_97066.9

UnificationXref1995
type: UnificationXref
id: 4189218
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189218

UnificationXref1994
type: UnificationXref
id: 4189216
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189216

SequenceSite5868
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5869
type: SequenceSite
position status: EQUAL
sequence position: 408

SequenceSite5864
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5865
type: SequenceSite
position status: EQUAL
sequence position: 1133

http://identifiers.org/pubmed/21540551
type: PublicationXref
id: 21540551
author: Matejas, V
author: Kispert, A
author: Casarin, A
author: Faul, C
author: Pertegato, V
author: Akman, S
author: Kusakabe, T
author: Wang, S
author: Santos-Ocaña, C
author: Krick, S
author: Doimo, M
author: Hildebrandt, F
author: Chernin, G
author: Vega-Warner, V
author: McLaughlin, HM
author: Nürnberg, G
author: Navas, P
author: Chaki, M
author: Schoeb, DS
author: Becker, C
author: Saisawat, P
author: Heeringa, SF
author: Varpizen, S
author: Prokisch, H
author: Wiggins, RC
author: Nürnberg, P
author: Beissert, A
author: Zhou, W
author: Bakkaloglu, A
author: Ji, Z
author: Xie, LX
author: Hinkes, B
author: Bakkaloglu, SA
author: Salviati, L
author: Reiser, J
author: Vlangos, CN
author: Mir, S
author: Airik, R
author: Topaloglu, R
author: Sloan, AJ
author: Rötig, A
author: Trevisson, E
author: Gbadegesin, R
author: Raphael, Y
author: Zenker, M
author: Clarke, CF
author: Ozaltin, F
author: Soliman, NA
author: Müller, D
author: Berdeli, A
author: Ashraf, S
author: Killen, PD
author: Mundel, P
author: Hurd, TW
author: Giorgi, G
author: Ovunc, B
db: Pubmed
title: COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness
source: J Clin Invest 121:2013-24
year: 2011

SequenceSite5866
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5867
type: SequenceSite
position status: EQUAL
sequence position: 708

Activation of NMDA receptor upon glutamate binding and postsynaptic events
type: Pathway
data source: Provenance1
pathway component: REACT 127141.5
evidence: Evidence1800
xref: UnificationXref19207
xref: UnificationXref19206
pathway order: PathwayStep1764
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

SequenceSite5874
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5873
type: SequenceSite
position status: EQUAL
sequence position: 408

SequenceSite5872
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5871
type: SequenceSite
position status: EQUAL
sequence position: 408

Stoichiometry2698
type: Stoichiometry
physical entity: SmallMolecule101
stoichiometric coefficient: 1.0

SequenceSite5870
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2697
type: Stoichiometry
physical entity: SmallMolecule37
stoichiometric coefficient: 2.0

Stoichiometry2699
type: Stoichiometry
physical entity: Protein7279
stoichiometric coefficient: 1.0

Stoichiometry2694
type: Stoichiometry
physical entity: SmallMolecule787
stoichiometric coefficient: 2.0

UnificationXref1976
type: UnificationXref
id: Q8GYW7
db: UniProt

Stoichiometry2693
type: Stoichiometry
physical entity: PhysicalEntity421
stoichiometric coefficient: 24.0

UnificationXref1977
type: UnificationXref
id: 4184798
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184798

Stoichiometry2696
type: Stoichiometry
physical entity: SmallMolecule1262
stoichiometric coefficient: 2.0

UnificationXref1978
type: UnificationXref
id: F4HU51
db: UniProt

Stoichiometry2695
type: Stoichiometry
physical entity: SmallMolecule104
stoichiometric coefficient: 2.0

UnificationXref1979
type: UnificationXref
id: 4184800
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184800

Stoichiometry2690
type: Stoichiometry
physical entity: SmallMolecule37
stoichiometric coefficient: 4.0

Mucopolysaccharidoses
type: Pathway
data source: Provenance1
pathway component: MPS IIID - Sanfilippo syndrome D
pathway component: REACT 149804.4
pathway component: REACT 149543.4
pathway component: REACT 148863.4
pathway component: REACT 149698.4
pathway component: REACT 148708.4
pathway component: REACT 149485.4
pathway component: REACT 149638.4
pathway component: REACT 149411.4
pathway component: REACT 149831.4
pathway component: REACT 149337.4
evidence: Evidence1850
xref: UnificationXref19688
xref: UnificationXref19687
pathway order: PathwayStep1803
pathway order: PathwayStep1802
pathway order: PathwayStep1810
pathway order: PathwayStep1806
pathway order: PathwayStep1801
pathway order: PathwayStep1800
pathway order: PathwayStep1808
pathway order: PathwayStep1804
pathway order: PathwayStep1809
pathway order: PathwayStep1805
pathway order: PathwayStep1807
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Stoichiometry2692
type: Stoichiometry
physical entity: SmallMolecule587
stoichiometric coefficient: 4.0

http://identifiers.org/pubmed/3391615
type: PublicationXref
id: 3391615
author: Robertson, D A
author: Baker, E G
author: Morris, C P
author: Hopwood, J J
author: Callen, D F
db: Pubmed
title: Chromosomal localization of the gene for human glucosamine-6-sulphatase to 12q14
source: Hum. Genet. 79:175-8
year: 1988

Stoichiometry2691
type: Stoichiometry
physical entity: SmallMolecule48
stoichiometric coefficient: 2.0

UnificationXref1980
type: UnificationXref
id: Q5FYU1
db: UniProt

UnificationXref1982
type: UnificationXref
id: 4184803
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184803

UnificationXref1981
type: UnificationXref
id: 4184802
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4184802

UnificationXref1984
type: UnificationXref
id: REACT_109012
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_109012.9

UnificationXref1983
type: UnificationXref
id: 4189220
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189220

UnificationXref1986
type: UnificationXref
id: REACT_31512
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_31512.10

UnificationXref1985
type: UnificationXref
id: 4199799
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199799

SequenceSite5879
type: SequenceSite
position status: EQUAL
sequence position: 408

SequenceSite5877
type: SequenceSite
position status: EQUAL
sequence position: 408

SequenceSite5878
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5875
type: SequenceSite
position status: EQUAL
sequence position: 408

SequenceSite5876
type: SequenceSite
position status: EQUAL
sequence position: 1

Exosome complex exonuclease RRP45
type: Protein
entity reference: Q9LDM2
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: EXOS9_HUMAN
name: EXOSC9 (RRP45)
name: Q9LDM2
xref: UnificationXref15005
feature: FragmentFeature4435
cellular location: GO:0005829
comment: Reactome DB_ID: 4190550
display name: EXOSC9

Exosome complex exonuclease RRP45
type: Protein
entity reference: Q8LGD7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Q8LGD7
name: EXOS9_HUMAN
name: EXOSC9 (RRP45)
xref: UnificationXref15003
feature: FragmentFeature4434
cellular location: GO:0005829
comment: Reactome DB_ID: 4190548
display name: EXOSC9

Q9M209
type: Protein
entity reference: Q9M209
data source: Provenance1
name: Exosome complex exonuclease RRP45
name: Note: the coordinates are copied over from Homo sapiens.
name: EXOS9_HUMAN
name: EXOSC9 (RRP45)
xref: UnificationXref15001
feature: FragmentFeature4433
cellular location: GO:0005829
comment: Reactome DB_ID: 4190544
display name: EXOSC9

Homologues of EXOSC9
type: Protein
data source: Provenance1
member physical entity: Q9M209
member physical entity: Exosome complex exonuclease RRP45
xref: UnificationXref15006
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4190551

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: A2RVK7
data source: Provenance1
name: EXOS6_HUMAN
name: Exosome complex exonuclease MTR3
name: A2RVK7
xref: UnificationXref14998
feature: FragmentFeature4432
cellular location: GO:0005829
comment: Reactome DB_ID: 4190523
display name: EXOSC6

Q8GWJ0
type: Protein
entity reference: Q8GWJ0
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: EXOS6_HUMAN
name: Exosome complex exonuclease MTR3
xref: UnificationXref14996
feature: FragmentFeature4431
cellular location: GO:0005829
comment: Reactome DB_ID: 4190521
display name: EXOSC6

UnificationXref17159
type: UnificationXref
id: Q94BM7
db: UniProt

UnificationXref17158
type: UnificationXref
id: 4188050
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188050

UnificationXref17157
type: UnificationXref
id: Q9LJR3
db: UniProt

UnificationXref17156
type: UnificationXref
id: 4188049
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188049

UnificationXref17155
type: UnificationXref
id: Q9SYX2
db: UniProt

UnificationXref17154
type: UnificationXref
id: 4188048
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188048

UnificationXref17153
type: UnificationXref
id: Q9T014
db: UniProt

UnificationXref17151
type: UnificationXref
id: 4199484
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199484

UnificationXref17152
type: UnificationXref
id: REACT_145850
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_145850.5

UnificationXref17150
type: UnificationXref
id: REACT_140327
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_140327.5

UnificationXref17169
type: UnificationXref
id: 4187881
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187881

UnificationXref17168
type: UnificationXref
id: 4187880
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187880

2'-Deoxyguanosine 5'-diphosphate
type: SmallMoleculeReference
name: dGDP [ChEBI:28862]
name: dGDP
xref: UnificationXref4967

UnificationXref17165
type: UnificationXref
id: 4187865
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187865

UnificationXref17164
type: UnificationXref
id: 4187860
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187860

UnificationXref17167
type: UnificationXref
id: 4187875
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187875

UnificationXref17166
type: UnificationXref
id: 4187870
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187870

UnificationXref17160
type: UnificationXref
id: 4188051
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188051

acidos grasos anionicos
type: SmallMoleculeReference
name: Fettsaeureanionen
name: fatty acid anion [ChEBI:28868]
name: fatty acid anions
name: Alkanate
name: fatty acid anion
name: anion de l'acide gras
name: acido graso anionico
name: Fettsaeureanion
xref: UnificationXref4422

UnificationXref17161
type: UnificationXref
id: P43254
db: UniProt

UnificationXref17162
type: UnificationXref
id: 4188052
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188052

UnificationXref17163
type: UnificationXref
id: 4188053
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188053

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O22823
data source: Provenance1
name: O22823
name: U6 snRNA-associated Sm-like protein LSm6
name: LSM6_HUMAN
xref: UnificationXref15044
feature: FragmentFeature4449
cellular location: GO:0005829
comment: Reactome DB_ID: 4190503
display name: LSM6

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9M1Z3
data source: Provenance1
name: U6 snRNA-associated Sm-like protein LSm6
name: LSM6_HUMAN
name: Q9M1Z3
xref: UnificationXref15042
feature: FragmentFeature4448
cellular location: GO:0005829
comment: Reactome DB_ID: 4190501
display name: LSM6

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LCS5
data source: Provenance1
name: Q8LCS5
name: U6 snRNA-associated Sm-like protein LSm6
name: LSM6_HUMAN
xref: UnificationXref15040
feature: FragmentFeature4447
cellular location: GO:0005829
comment: Reactome DB_ID: 4190499
display name: LSM6

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: B9DI28
data source: Provenance1
name: B9DI28
name: U6 snRNA-associated Sm-like protein LSm6
name: LSM6_HUMAN
xref: UnificationXref15038
feature: FragmentFeature4446
cellular location: GO:0005829
comment: Reactome DB_ID: 4190495
display name: LSM6

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZVT4
data source: Provenance1
name: U6 snRNA-associated Sm-like protein LSm2
name: Q9ZVT4
name: LSM2_HUMAN
xref: UnificationXref15051
feature: FragmentFeature4452
cellular location: GO:0005829
comment: Reactome DB_ID: 4190507
display name: LSM2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q1H595
data source: Provenance1
name: U6 snRNA-associated Sm-like protein LSm2
name: Q1H595
name: LSM2_HUMAN
xref: UnificationXref15049
feature: FragmentFeature4451
cellular location: GO:0005829
comment: Reactome DB_ID: 4190506
display name: LSM2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8L5U6
data source: Provenance1
name: U6 snRNA-associated Sm-like protein LSm2
name: LSM2_HUMAN
name: Q8L5U6
xref: UnificationXref15047
feature: FragmentFeature4450
cellular location: GO:0005829
comment: Reactome DB_ID: 4190505
display name: LSM2

Homologues of LSM2
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15052
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4190508

UnificationXref17178
type: UnificationXref
id: 4187888
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187888

UnificationXref17177
type: UnificationXref
id: 4187887
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187887

UnificationXref17176
type: UnificationXref
id: 4187886
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187886

UnificationXref17175
type: UnificationXref
id: 4187885
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187885

UnificationXref17179
type: UnificationXref
id: REACT_109372
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_109372.9

UnificationXref17170
type: UnificationXref
id: 4188054
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188054

UnificationXref17173
type: UnificationXref
id: 4187883
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187883

UnificationXref17174
type: UnificationXref
id: 4187884
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187884

UnificationXref17171
type: UnificationXref
id: REACT_77690
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_77690.9

UnificationXref17172
type: UnificationXref
id: 4187882
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187882

Homologues of LSM6
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15045
cellular location: GO:0005829
comment: Reactome DB_ID: 4190504
comment: Converted from EntitySet in Reactome

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SHL7
data source: Provenance1
name: Exosome complex exonuclease RRP44
name: RRP44_HUMAN
name: Q9SHL7
xref: UnificationXref15027
feature: FragmentFeature4444
cellular location: GO:0005829
comment: Reactome DB_ID: 4190558
display name: DIS3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SI54
data source: Provenance1
name: Q9SI54
name: LSM7_HUMAN
name: U6 snRNA-associated Sm-like protein LSm7
xref: UnificationXref15035
feature: FragmentFeature4445
cellular location: GO:0005829
comment: Reactome DB_ID: 4190512
display name: LSM7

Interconversion of 2-oxoglutarate and 2-hydroxyglutarate
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction309
pathway component: BiochemicalReaction308
evidence: Evidence432
xref: UnificationXref4368
xref: UnificationXref4369
xref: RelationshipXref508
pathway order: PathwayStep429
pathway order: PathwayStep428
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Homologues of EXOSC3
type: Protein
data source: Provenance1
member physical entity: Q94AW9
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15023
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4190572

Q94AW9
type: Protein
entity reference: Q94AW9
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: EXOS3_HUMAN
name: Exosome complex exonuclease RRP40
xref: UnificationXref15018
feature: FragmentFeature4440
cellular location: GO:0005829
comment: Reactome DB_ID: 4190565
display name: EXOSC3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: A8MQZ8
data source: Provenance1
name: A8MQZ8
name: EXOS3_HUMAN
name: Exosome complex exonuclease RRP40
xref: UnificationXref15016
feature: FragmentFeature4439
cellular location: GO:0005829
comment: Reactome DB_ID: 4190563
display name: EXOSC3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q500X1
data source: Provenance1
name: EXOS3_HUMAN
name: Exosome complex exonuclease RRP40
name: Q500X1
xref: UnificationXref15022
feature: FragmentFeature4442
cellular location: GO:0005829
comment: Reactome DB_ID: 4190571
display name: EXOSC3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q56XA4
data source: Provenance1
name: Q56XA4
name: EXOS3_HUMAN
name: Exosome complex exonuclease RRP40
xref: UnificationXref15020
feature: FragmentFeature4441
cellular location: GO:0005829
comment: Reactome DB_ID: 4190569
display name: EXOSC3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: F4INI6
data source: Provenance1
name: Exosome complex exonuclease RRP44
name: F4INI6
name: RRP44_HUMAN
xref: UnificationXref15025
feature: FragmentFeature4443
cellular location: GO:0005829
comment: Reactome DB_ID: 4190556
display name: DIS3

Homologues of DIS3
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15028
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4190559

UnificationXref17187
type: UnificationXref
id: 4199757
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199757

UnificationXref17186
type: UnificationXref
id: REACT_89167
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_89167.9

UnificationXref17189
type: UnificationXref
id: 4199758
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199758

UnificationXref17188
type: UnificationXref
id: REACT_110976
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_110976.9

PublicationXref768
type: PublicationXref
id: 0079130356
author: Webster, DR
author: Becroft, DM
author: van Kuilenberg, AB
author: van Gennip, AH
db: ISBN
title: Hereditary orotic aciduria and other disorders of pyrimidine metabolism
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 2663-2704
year: 2001

UnificationXref17180
type: UnificationXref
id: 4187889
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187889

UnificationXref17181
type: UnificationXref
id: 4187891
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187891

UnificationXref17182
type: UnificationXref
id: REACT_129090
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_129090.5

UnificationXref17183
type: UnificationXref
id: 4187892
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187892

UnificationXref17184
type: UnificationXref
id: REACT_128837
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_128837.5

UnificationXref17185
type: UnificationXref
id: 4199756
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199756

Homologues of EXOSC1
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15012
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4190583

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: A2RVT9
data source: Provenance1
name: A2RVT9
name: 3'-5' exoribonuclease CSL4 homolog
name: EXOS1_HUMAN
xref: UnificationXref15009
feature: FragmentFeature4436
cellular location: GO:0005829
comment: Reactome DB_ID: 4190580
display name: EXOSC1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FMB3
data source: Provenance1
name: Q9FMB3
name: 3'-5' exoribonuclease CSL4 homolog
name: EXOS1_HUMAN
xref: UnificationXref15011
feature: FragmentFeature4437
cellular location: GO:0005829
comment: Reactome DB_ID: 4190582
display name: EXOSC1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9ZVT7
data source: Provenance1
name: EXOS2_HUMAN
name: Exosome complex exonuclease RRP4
name: Q9ZVT7
xref: UnificationXref15014
feature: FragmentFeature4438
cellular location: GO:0005829
comment: Reactome DB_ID: 4190576
display name: EXOSC2

UnificationXref17115
type: UnificationXref
id: 4199727
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199727

UnificationXref17116
type: UnificationXref
id: REACT_85811
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_85811.9

UnificationXref17113
type: UnificationXref
id: 4187460
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187460

UnificationXref17114
type: UnificationXref
id: REACT_120458
db: Reactome
id version: 6
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_120458.6

UnificationXref17111
type: UnificationXref
id: 4187458
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187458

UniProt:F4K1D3
type: ProteinReference
xref: UnificationXref9254
organism: Arabidopsis thaliana

UnificationXref17112
type: UnificationXref
id: 4187459
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187459

UnificationXref17110
type: UnificationXref
id: 4187457
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187457

UnificationXref17119
type: UnificationXref
id: 4186950
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186950

UnificationXref17117
type: UnificationXref
id: 426472
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=426472

UnificationXref17118
type: UnificationXref
id: REACT_120073
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_120073.1

http://identifiers.org/pubmed/1976634
type: PublicationXref
id: 1976634
author: Hurwitz, J
author: Lee, SH
author: Kwong, AD
db: Pubmed
title: The in vitro replication of DNA containing the SV40 origin.
source: J Biol Chem 265:18043-6
year: 1990

Acyl chain remodelling of PC
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction196
pathway component: BiochemicalReaction195
pathway component: BiochemicalReaction197
evidence: Evidence271
xref: UnificationXref2813
xref: RelationshipXref322
xref: UnificationXref2812
pathway order: PathwayStep269
pathway order: PathwayStep267
pathway order: PathwayStep268
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

UnificationXref17124
type: UnificationXref
id: REACT_126903
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_126903.5

UnificationXref17125
type: UnificationXref
id: 4198091
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4198091

UnificationXref17126
type: UnificationXref
id: 4198092
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4198092

UnificationXref17127
type: UnificationXref
id: 4198093
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4198093

UnificationXref17120
type: UnificationXref
id: 426446
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=426446

UnificationXref17121
type: UnificationXref
id: REACT_119919
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_119919.1

UnificationXref17122
type: UnificationXref
id: 4186951
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186951

UnificationXref17123
type: UnificationXref
id: 4186953
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4186953

http://identifiers.org/pubmed/19926846
type: PublicationXref
id: 19926846
author: Saitoh, T
author: Hayashi, Takuya
author: Matsunaga, Kohichi
author: Lee, Hanna
author: Satoh, T
author: Akira, S
author: Takeuchi, O
author: Noda, Takeshi
author: Ishii, Ken
author: Fujita, Naonobu
author: Kageyama, Shun
author: Takahara, Keigo
author: Omori, Hiroko
author: Kawai, T
author: Yamamoto, Naoki
author: Yoshimori, Tamotsu
db: Pubmed
title: Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
source: Proc. Natl. Acad. Sci. U.S.A. 106:20842-6
year: 2009

http://identifiers.org/pubmed/7913309
type: PublicationXref
id: 7913309
author: Rokosz, LL
author: Cueto, MA
author: Butkiewicz, EA
author: Hermes, JD
author: Boulton, DA
author: Sanyal, G
author: Lachance, PA
db: Pubmed
title: Human cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase: expression, purification, and characterization of recombinant wild-type and Cys129 mutant enzymes
source: Arch Biochem Biophys 312:1-13
year: 1994

UnificationXref17128
type: UnificationXref
id: 4198094
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4198094

UnificationXref17129
type: UnificationXref
id: 4189749
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189749

Stoichiometry2500
type: Stoichiometry
physical entity: PhysicalEntity387
stoichiometric coefficient: 1.0

Stoichiometry2502
type: Stoichiometry
physical entity: Protein6539
stoichiometric coefficient: 1.0

Stoichiometry2501
type: Stoichiometry
physical entity: PhysicalEntity389
stoichiometric coefficient: 1.0

Stoichiometry2504
type: Stoichiometry
physical entity: Protein6540
stoichiometric coefficient: 1.0

Stoichiometry2503
type: Stoichiometry
physical entity: PhysicalEntity235
stoichiometric coefficient: 1.0

Stoichiometry2506
type: Stoichiometry
physical entity: PhysicalEntity392
stoichiometric coefficient: 1.0

Stoichiometry2505
type: Stoichiometry
physical entity: PhysicalEntity227
stoichiometric coefficient: 1.0

UnificationXref17133
type: UnificationXref
id: 4198096
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4198096

UnificationXref17134
type: UnificationXref
id: 4199729
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199729

UnificationXref17131
type: UnificationXref
id: 4189751
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189751

UnificationXref17132
type: UnificationXref
id: 4198095
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4198095

UnificationXref17137
type: UnificationXref
id: REACT_119046
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_119046.1

UnificationXref17138
type: UnificationXref
id: 426511
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=426511

UnificationXref17135
type: UnificationXref
id: REACT_120630
db: Reactome
id version: 6
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_120630.6

UnificationXref17136
type: UnificationXref
id: 426523
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=426523

UnificationXref17139
type: UnificationXref
id: REACT_119521
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_119521.1

http://identifiers.org/pubmed/19244215
type: PublicationXref
id: 19244215
author: Buczynski, MW
author: Dumlao, DS
author: Dennis, EA
db: Pubmed
title: Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology
source: J Lipid Res 50:1015-38
year: 2009

http://identifiers.org/pubmed/12648452
type: PublicationXref
id: 12648452
author: Buttgereit, F
author: Qian, SB
author: Finzi, D
author: Princiotta, MF
author: Yewdell, JW
author: Gibbs, J
author: Bennink, JR
author: Schuchmann, S
db: Pubmed
title: Quantitating protein synthesis, degradation, and endogenous antigen processing
source: Immunity 18:343-54
year: 2003

UnificationXref17130
type: UnificationXref
id: 4189750
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189750

UnificationXref17142
type: UnificationXref
id: REACT_120378
db: Reactome
id version: 6
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_120378.6

UnificationXref17143
type: UnificationXref
id: 4199829
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199829

HxB3
type: SmallMoleculeReference
name: (5Z,8Z,14Z)-(11R,12S)-11,12-Epoxy-10-hydroxyicosa-5,8,14-trienoic acid
name: hepoxilin B3 [ChEBI:34784]
name: hepoxilin B3
name: HXB3
name: 10-hydroxy-11R,12S-epoxy-5Z,8Z,14Z-eicosatrienoic acid
name: (5Z,8Z,14Z)-(11R,12S)-11,12-Epoxy-10-hydroxyeicosa-5,8,14-trienoic acid
xref: UnificationXref3566

UnificationXref17144
type: UnificationXref
id: REACT_120504
db: Reactome
id version: 6
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_120504.6

Phosphorylation of FANCD2 by ATR/ATM
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1041
EC number: 2.7.11
xref: UnificationXref11420
xref: UnificationXref11421
left: SmallMolecule921
left: Protein3849
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3849

UnificationXref17145
type: UnificationXref
id: 4199728
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199728

UnificationXref17146
type: UnificationXref
id: REACT_29332
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_29332.10

Degradation of multiubiquitinated Nek2A
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1046
xref: UnificationXref11502
xref: UnificationXref11503
participant stoichiometry: Stoichiometry1441
left: Complex517
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3409
right: Complex519

UnificationXref17147
type: UnificationXref
id: 4199417
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199417

Phosphorylation of FANCI by ATM/ATR
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1042
EC number: 2.7.11
xref: UnificationXref11422
xref: UnificationXref11423
left: Protein3861
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3861

UnificationXref17148
type: UnificationXref
id: REACT_91657
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_91657.9

Na+/Ca2+ exchanger transport
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1049
xref: UnificationXref11527
xref: UnificationXref11526
participant stoichiometry: Stoichiometry1447
participant stoichiometry: Stoichiometry1446
left: SmallMolecule631
left: SmallMolecule104
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule634
right: SmallMolecule961

UnificationXref17149
type: UnificationXref
id: 4199483
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199483

ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1048
EC number: 3.6.3.8
xref: UnificationXref11518
xref: UnificationXref11517
participant stoichiometry: Stoichiometry1442
participant stoichiometry: Stoichiometry1444
participant stoichiometry: Stoichiometry1443
participant stoichiometry: Stoichiometry1445
left: SmallMolecule959
left: SmallMolecule104
display name: Sequestration of Ca2+ to dense tubular network lumen
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule960
right: SmallMolecule37

http://identifiers.org/pubmed/9852097
type: PublicationXref
id: 9852097
author: Kerr, TA
author: Russell, DW
author: Li, WP
author: Sakai, J
author: Lund, EG
db: Pubmed
title: cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism
source: J Biol Chem 273:34316-27
year: 1998

UnificationXref17141
type: UnificationXref
id: 4189755
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189755

UnificationXref17140
type: UnificationXref
id: 4189753
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4189753

Exocytosis of platelet alpha granule contents
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1062
xref: UnificationXref11662
xref: UnificationXref11663
left: Protein3982
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3993

PLC gamma 2-mediated PIP2 hydrolysis
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1056
xref: UnificationXref11572
xref: UnificationXref11573
left: SmallMolecule101
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule103
right: SmallMolecule458

Src activation following P2Y purinoceptor activation
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1053
xref: UnificationXref11557
xref: UnificationXref11556
left: Protein3907
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3918

DAG kinase produces phosphatidic acid from DAG
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1060
EC number: 2.7.1.107
xref: UnificationXref11635
xref: UnificationXref11636
left: SmallMolecule11
left: SmallMolecule458
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule964
right: SmallMolecule14

2-AG hydrolysis to arachidonate by MAGL
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1058
EC number: 3.1.1.23
xref: UnificationXref11589
xref: UnificationXref11588
left: SmallMolecule962
left: SmallMolecule48
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule963
right: SmallMolecule168
right: SmallMolecule37

http://identifiers.org/pubmed/13416257
type: PublicationXref
id: 13416257
author: Robinson, WG
author: Coon, MJ
db: Pubmed
title: Purification and properties of beta-hydroxyisobutyric dehydrogenase
source: J Biol Chem 225:511-521
year: 1957

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q9FM47
data source: Provenance1
xref: UnificationXref15164
feature: ModificationFeature406
feature: FragmentFeature4506
feature: ModificationFeature405
cellular location: GO:0005829
comment: Reactome DB_ID: 4191711

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: F4JFN7
data source: Provenance1
xref: UnificationXref15163
feature: ModificationFeature404
feature: ModificationFeature403
feature: FragmentFeature4505
cellular location: GO:0005829
comment: Reactome DB_ID: 4191708

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: B9DHV1
data source: Provenance1
xref: UnificationXref15166
feature: FragmentFeature4508
feature: ModificationFeature409
feature: ModificationFeature410
cellular location: GO:0005829
comment: Reactome DB_ID: 4191717

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: F4I906
data source: Provenance1
xref: UnificationXref15165
feature: FragmentFeature4507
feature: ModificationFeature407
feature: ModificationFeature408
cellular location: GO:0005829
comment: Reactome DB_ID: 4191714

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: F4JV21
data source: Provenance1
xref: UnificationXref15160
feature: ModificationFeature397
feature: ModificationFeature398
feature: FragmentFeature4502
cellular location: GO:0005829
comment: Reactome DB_ID: 4191699

Release of Calumenin
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1065
xref: UnificationXref11781
xref: UnificationXref11780
left: Protein4075
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein4078

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q94A00
data source: Provenance1
xref: UnificationXref15159
feature: FragmentFeature4501
feature: ModificationFeature396
feature: ModificationFeature395
cellular location: GO:0005829
comment: Reactome DB_ID: 4191696

Release of 78 kDa glucose-regulated protein
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1066
xref: UnificationXref11800
xref: UnificationXref11799
left: Protein4081
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein4087

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q9SM01
data source: Provenance1
xref: UnificationXref15162
feature: ModificationFeature401
feature: FragmentFeature4504
feature: ModificationFeature402
cellular location: GO:0005829
comment: Reactome DB_ID: 4191705

antithrombin III + heparin -> antithrombin III:heparin
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1070
xref: UnificationXref11843
xref: UnificationXref11842
left: Protein4093
left: PhysicalEntity210
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex522

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: B5BRC9
data source: Provenance1
xref: UnificationXref15161
feature: ModificationFeature400
feature: ModificationFeature399
feature: FragmentFeature4503
cellular location: GO:0005829
comment: Reactome DB_ID: 4191702

RAD51B binds RAD51C
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1073
xref: UnificationXref11853
xref: UnificationXref11854
left: Protein4115
left: Protein4116
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex523

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: F4K4W6
data source: Provenance1
xref: UnificationXref15158
feature: ModificationFeature393
feature: ModificationFeature394
feature: FragmentFeature4500
cellular location: GO:0005829
comment: Reactome DB_ID: 4191693

Release of platelet cytosolic components
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1063
xref: UnificationXref11725
xref: UnificationXref11726
left: PhysicalEntity206
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity207

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: B9DGK8
data source: Provenance1
xref: UnificationXref15157
feature: ModificationFeature392
feature: ModificationFeature391
feature: FragmentFeature4499
cellular location: GO:0005829
comment: Reactome DB_ID: 4191690

Release of (inferred) platelet cytosolic components
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1064
xref: UnificationXref11770
xref: UnificationXref11771
left: PhysicalEntity208
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity209

ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1077
xref: UnificationXref11866
xref: UnificationXref11865
left: SmallMolecule11
left: SmallMolecule107
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule108
right: SmallMolecule14

ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1076
xref: UnificationXref11864
xref: UnificationXref11863
left: SmallMolecule11
left: SmallMolecule107
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule106
right: SmallMolecule14

ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1075
EC number: 2.7.1.134
xref: UnificationXref11862
xref: UnificationXref11861
left: SmallMolecule11
left: SmallMolecule125
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule124
right: SmallMolecule14

RAD51B:RAD51C binds single-stranded DNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1074
xref: UnificationXref11860
xref: UnificationXref11859
left: Complex523
left: SmallMolecule965
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex524

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q9FJ56
data source: Provenance1
xref: UnificationXref15156
feature: FragmentFeature4498
feature: ModificationFeature390
feature: ModificationFeature389
cellular location: GO:0005829
comment: Reactome DB_ID: 4191687

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q9LHL2
data source: Provenance1
xref: UnificationXref15155
feature: FragmentFeature4497
feature: ModificationFeature387
feature: ModificationFeature388
cellular location: GO:0005829
comment: Reactome DB_ID: 4191684

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q8W569
data source: Provenance1
xref: UnificationXref15154
feature: FragmentFeature4496
feature: ModificationFeature385
feature: ModificationFeature386
cellular location: GO:0005829
comment: Reactome DB_ID: 4191681

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q9SFD3
data source: Provenance1
xref: UnificationXref15153
feature: FragmentFeature4495
feature: ModificationFeature384
feature: ModificationFeature383
cellular location: GO:0005829
comment: Reactome DB_ID: 4191678

Homologues of p-S83,S87-HNRNPD-3
type: Protein
data source: Provenance1
member physical entity: phospho-p-S83,S87-HNRNPD-3
xref: UnificationXref15182
cellular location: GO:0005829
comment: Reactome DB_ID: 4191763
comment: Converted from EntitySet in Reactome

HNRNPD-4
type: Protein
entity reference: Q8W034
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15150
feature: FragmentFeature4494
cellular location: GO:0005829
comment: Reactome DB_ID: 4191673
display name: Q8W034

Kinesin-8 is a dimer
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1083
xref: UnificationXref11969
xref: UnificationXref11970
participant stoichiometry: Stoichiometry1466
left: Protein4170
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex533

HNRNPD-4
type: Protein
entity reference: Q8W555
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15148
feature: FragmentFeature4493
cellular location: GO:0005829
comment: Reactome DB_ID: 4191672
display name: Q8W555

Kinesin-12 is a dimer
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1084
xref: UnificationXref11991
xref: UnificationXref11992
participant stoichiometry: Stoichiometry1468
left: Protein4171
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex534

HNRNPD-4
type: Protein
entity reference: O22791
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15146
feature: FragmentFeature4492
cellular location: GO:0005829
comment: Reactome DB_ID: 4191671
display name: O22791

Kinesin-5 is a homotetramer
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1081
xref: UnificationXref11952
xref: UnificationXref11953
participant stoichiometry: Stoichiometry1462
left: Protein4159
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex531

HNRNPD-4
type: Protein
entity reference: Q8VZ63
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15144
feature: FragmentFeature4491
cellular location: GO:0005829
comment: Reactome DB_ID: 4191670
display name: Q8VZ63

Kinesin-7 is a dimer
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1082
xref: UnificationXref11965
xref: UnificationXref11964
participant stoichiometry: Stoichiometry1464
left: Protein4165
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex532

HNRNPD-4
type: Protein
entity reference: Q8L779
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15142
feature: FragmentFeature4490
cellular location: GO:0005829
comment: Reactome DB_ID: 4191669
display name: Q8L779

DOCKs bind to RhoGEFs
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1079
xref: UnificationXref11900
xref: UnificationXref11901
left: PhysicalEntity212
left: PhysicalEntity211
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex526

Chromokinesins form dimers
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1080
xref: UnificationXref11939
xref: UnificationXref11938
participant stoichiometry: Stoichiometry1458
left: PhysicalEntity213
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity215

F-actin capping protein is a heterodimer
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1078
xref: UnificationXref11872
xref: UnificationXref11873
left: Protein4117
left: Protein4118
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex525

Removal of SPO11 and Resection of 5' Ends of DNA
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1089
xref: UnificationXref12016
xref: UnificationXref12015
left: Complex536
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex537
right: PhysicalEntity184

Formation of Double-strand Break in DNA by SPO11
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1088
EC number: 3.1.21
xref: UnificationXref12008
xref: UnificationXref12009
left: Complex535
left: PhysicalEntity216
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex536

http://identifiers.org/pubmed/12176931
type: PublicationXref
id: 12176931
author: Lamond, AI
author: Ryder, U
author: Rappsilber, J
author: Mann, M
db: Pubmed
title: Large-scale proteomic analysis of the human spliceosome.
source: Genome Res 12:1231-45
year: 2002

Orc3 associates with Orc2 constitutively bound at origins of replication
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1092
xref: UnificationXref12029
xref: UnificationXref12030
left: Protein4185
left: Complex539
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex540

Orc5 associates with Orc3:Orc2:origin complexes
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1093
xref: UnificationXref12034
xref: UnificationXref12035
left: Complex540
left: Protein4186
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex541

Orc4 associates with Orc5:Orc3:Orc2:origin complexes
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1094
xref: UnificationXref12049
xref: UnificationXref12048
left: Protein4187
left: Complex541
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex542

Orc1 associates with Orc4:Orc5:Orc3:Orc2:origin complexes
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1095
xref: UnificationXref12059
xref: UnificationXref12058
left: Protein4193
left: Complex542
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex543

Orc6 associates with Orc1:Orc4:Orc5:Orc3:Orc2:origin complexes, forming ORC:origin complexes
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1096
xref: UnificationXref12063
xref: UnificationXref12064
left: Complex543
left: Protein4197
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex544

Association of MCM8 with ORC:origin complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1098
xref: UnificationXref12072
xref: UnificationXref12071
left: Protein4198
left: Complex544
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex545

CDC6 association with ORC:origin complexes mediated by MCM8
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1100
xref: UnificationXref12085
xref: UnificationXref12086
left: Protein4199
left: Complex545
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex547

Mcm2-7 associates with the Cdt1:CDC6:ORC:origin complex, forming the pre-replicative complex (preRC)
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1102
xref: UnificationXref12141
xref: UnificationXref12140
left: Complex549
left: Complex548
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex550

Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1104
xref: UnificationXref12148
xref: UnificationXref12147
left: Complex550
left: Protein4229
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex551

DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1106
xref: UnificationXref12172
xref: UnificationXref12173
left: Complex558
left: Complex557
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex559

Cdc45 associates with the pre-replicative complex at the origin
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1105
xref: UnificationXref12164
xref: UnificationXref12163
left: Protein4230
left: Complex552
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex557

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: F4JYK6
data source: Provenance1
xref: UnificationXref15176
feature: ModificationFeature429
feature: FragmentFeature4518
feature: ModificationFeature430
cellular location: GO:0005829
comment: Reactome DB_ID: 4191747

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: O23288
data source: Provenance1
xref: UnificationXref15175
feature: FragmentFeature4517
feature: ModificationFeature427
feature: ModificationFeature428
cellular location: GO:0005829
comment: Reactome DB_ID: 4191744

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q9SSE0
data source: Provenance1
xref: UnificationXref15174
feature: ModificationFeature425
feature: FragmentFeature4516
feature: ModificationFeature426
cellular location: GO:0005829
comment: Reactome DB_ID: 4191741

DNA polymerase alpha:primase binds at the origin
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1107
xref: UnificationXref12201
xref: UnificationXref12200
left: Complex562
left: Complex560
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex563

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q0WNB9
data source: Provenance1
xref: UnificationXref15169
feature: ModificationFeature415
feature: ModificationFeature416
feature: FragmentFeature4511
cellular location: GO:0005829
comment: Reactome DB_ID: 4191726

The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1113
EC number: 2.7.7.7
xref: UnificationXref12228
xref: UnificationXref12229
left: SmallMolecule967
left: SmallMolecule966
left: Complex564
left: SmallMolecule968
left: SmallMolecule969
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex565

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q8LDS6
data source: Provenance1
xref: UnificationXref15168
feature: ModificationFeature413
feature: ModificationFeature414
feature: FragmentFeature4510
cellular location: GO:0005829
comment: Reactome DB_ID: 4191723

Orc1 is phosphorylated by cyclin A/CDK2
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1115
xref: UnificationXref12284
xref: UnificationXref12283
left: Complex550
left: SmallMolecule110
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein4250
right: Complex566
right: SmallMolecule113

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: F4JYK7
data source: Provenance1
xref: UnificationXref15167
feature: ModificationFeature411
feature: FragmentFeature4509
feature: ModificationFeature412
cellular location: GO:0005829
comment: Reactome DB_ID: 4191720

DNA polymerase epsilon binds at the origin
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1108
xref: UnificationXref12203
xref: UnificationXref12204
left: Complex561
left: PhysicalEntity219
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex560

The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1112
EC number: 2.7.7.6
xref: UnificationXref12216
xref: UnificationXref12215
left: SmallMolecule922
left: Complex563
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex564
right: Complex561

http://identifiers.org/pubmed/12807903
type: PublicationXref
id: 12807903
author: Nagai, M
author: Sudol, M
author: Navin, NE
author: Komuro, A
db: Pubmed
title: WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus
source: J Biol Chem 278:33334-41
year: 2003

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q9SU99
data source: Provenance1
xref: UnificationXref15173
feature: ModificationFeature423
feature: ModificationFeature424
feature: FragmentFeature4515
cellular location: GO:0005829
comment: Reactome DB_ID: 4191738

Ubiquitinated Orc1 is degraded by the proteasome
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1118
xref: UnificationXref12296
xref: UnificationXref12295
left: Complex570
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3409

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q949Z3
data source: Provenance1
xref: UnificationXref15172
feature: ModificationFeature422
feature: FragmentFeature4514
feature: ModificationFeature421
cellular location: GO:0005829
comment: Reactome DB_ID: 4191735

Cdc6 protein is phosphorylated by CDK
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1120
xref: UnificationXref12299
xref: UnificationXref12300
left: Protein4199
left: SmallMolecule110
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein4199
right: SmallMolecule113

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q8W4A6
data source: Provenance1
xref: UnificationXref15171
feature: FragmentFeature4513
feature: ModificationFeature420
feature: ModificationFeature419
cellular location: GO:0005829
comment: Reactome DB_ID: 4191732

Phosphorylated Orc1 is ubiquitinated while still associated with chromatin
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1116
xref: UnificationXref12287
xref: UnificationXref12286
left: Protein3850
left: Protein4250
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex569

phospho-p-S83,S87-HNRNPD-3
type: Protein
entity reference: Q9C652
data source: Provenance1
xref: UnificationXref15170
feature: ModificationFeature417
feature: FragmentFeature4512
feature: ModificationFeature418
cellular location: GO:0005829
comment: Reactome DB_ID: 4191729

Ubiquitinated Orc1 enters the cytosol
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1117
xref: UnificationXref12294
xref: UnificationXref12293
left: Complex569
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex570

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LFL8
data source: Provenance1
name: U6 snRNA-associated Sm-like protein LSm1
name: Q8LFL8
name: LSM1_HUMAN
xref: UnificationXref15072
feature: FragmentFeature4461
cellular location: GO:0005829
comment: Reactome DB_ID: 4190461
display name: LSM1

UnificationXref17194
type: UnificationXref
id: REACT_99557
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_99557.9

UnificationXref17193
type: UnificationXref
id: 4199760
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199760

UnificationXref17196
type: UnificationXref
id: Q9LTY1
db: UniProt

UnificationXref17195
type: UnificationXref
id: 4182731
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182731

UnificationXref17190
type: UnificationXref
id: REACT_80077
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_80077.9

Phosphorylated Cdc6 is exported from the nucleus
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1121
xref: UnificationXref12307
xref: UnificationXref12306
left: Protein4199
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein4286

UnificationXref17192
type: UnificationXref
id: REACT_94187
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_94187.9

UnificationXref17191
type: UnificationXref
id: 4199759
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199759

RFC dissociates after sliding clamp formation
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1132
xref: UnificationXref12374
xref: UnificationXref12373
left: Complex578
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex579
right: Complex575

Loading of PCNA - Sliding Clamp Formation
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1131
xref: UnificationXref12370
xref: UnificationXref12371
left: Complex577
left: SmallMolecule110
left: Complex576
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex578
right: SmallMolecule113

Homologues of LSM4
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15082
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4190484

Processive synthesis on the leading strand
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1135
xref: UnificationXref12380
xref: UnificationXref12381
left: Complex579
left: Complex481
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex580

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LAC6
data source: Provenance1
name: LSM4_HUMAN
name: Q8LAC6
name: U6 snRNA-associated Sm-like protein LSm4
xref: UnificationXref15075
feature: FragmentFeature4462
cellular location: GO:0005829
comment: Reactome DB_ID: 4190477
display name: LSM4

Formation of Processive Complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1133
xref: UnificationXref12377
xref: UnificationXref12376
left: Complex579
left: Complex481
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex580

UnificationXref17197
type: UnificationXref
id: 4182735
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182735

MCM8 mediated fork unwinding
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1127
xref: UnificationXref12329
xref: UnificationXref12330
left: PhysicalEntity228
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity229

UnificationXref17198
type: UnificationXref
id: 4182736
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182736

MCM2-7 mediated fork unwinding
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1126
xref: UnificationXref12328
xref: UnificationXref12327
left: PhysicalEntity228
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity229

UnificationXref17199
type: UnificationXref
id: 4182741
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182741

RFC binding displaces Pol Alpha
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1130
xref: UnificationXref12367
xref: UnificationXref12366
left: Complex575
left: Complex565
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex576

Multiple proteins are localized at replication fork
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1128
xref: UnificationXref12344
xref: UnificationXref12343
left: Protein4230
left: Complex548
left: PhysicalEntity228
left: Complex573
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex574

HNRNPD-4
type: Protein
entity reference: Q9SFD3
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15094
feature: FragmentFeature4466
cellular location: GO:0005829
comment: Reactome DB_ID: 4191645
display name: Q9SFD3

HNRNPD-4
type: Protein
entity reference: Q8W569
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15096
feature: FragmentFeature4467
cellular location: GO:0005829
comment: Reactome DB_ID: 4191646
display name: Q8W569

HNRNPD-4
type: Protein
entity reference: Q9LHL2
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15098
feature: FragmentFeature4468
cellular location: GO:0005829
comment: Reactome DB_ID: 4191647
display name: Q9LHL2

Mcm4,6,7 trimer forms and associates with the replication fork
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1124
xref: UnificationXref12319
xref: UnificationXref12320
left: Complex548
display name: Rearrangement and mobilization of Mcm2-7
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein4208
right: Complex572
right: Protein4214
right: Protein4209

HNRNPD-4
type: Protein
entity reference: Q9FJ56
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15100
feature: FragmentFeature4469
cellular location: GO:0005829
comment: Reactome DB_ID: 4191648
display name: Q9FJ56

Ubiquitinated Cdc6 is degraded by the proteasome
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1122
xref: UnificationXref12314
xref: UnificationXref12315
left: Complex571
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3409

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:F4K4E3
data source: Provenance1
name: LSM4_HUMAN
name: F4K4E3
name: U6 snRNA-associated Sm-like protein LSm4
xref: UnificationXref15077
feature: FragmentFeature4463
cellular location: GO:0005829
comment: Reactome DB_ID: 4190479
display name: LSM4

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q42186
data source: Provenance1
name: LSM4_HUMAN
name: U6 snRNA-associated Sm-like protein LSm4
name: Q42186
xref: UnificationXref15079
feature: FragmentFeature4464
cellular location: GO:0005829
comment: Reactome DB_ID: 4190481
display name: LSM4

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8RWJ9
data source: Provenance1
name: LSM4_HUMAN
name: U6 snRNA-associated Sm-like protein LSm4
name: Q8RWJ9
xref: UnificationXref15081
feature: FragmentFeature4465
cellular location: GO:0005829
comment: Reactome DB_ID: 4190483
display name: LSM4

Homologues of HNRNPD-4
type: Protein
data source: Provenance1
member physical entity: HNRNPD-4
xref: UnificationXref15151
cellular location: GO:0005829
comment: Reactome DB_ID: 4191674
comment: Converted from EntitySet in Reactome

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q0WMZ9
data source: Provenance1
name: LSM5_HUMAN
name: U6 snRNA-associated Sm-like protein LSm5
name: Q0WMZ9
name: LSM5(2-91)
xref: UnificationXref15054
feature: FragmentFeature4453
cellular location: GO:0005829
comment: Reactome DB_ID: 4190488
display name: LSM5

Homologues of LSM5(2-91)
type: Protein
data source: Provenance1
member physical entity: Q9FKB0
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15057
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4190491

Q9FKB0
type: Protein
entity reference: Q9FKB0
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: LSM5_HUMAN
name: U6 snRNA-associated Sm-like protein LSm5
name: LSM5(2-91)
xref: UnificationXref15056
feature: FragmentFeature4454
cellular location: GO:0005829
comment: Reactome DB_ID: 4190490
display name: LSM5

Activation of S6K1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1166
xref: UnificationXref12524
xref: UnificationXref12523
participant stoichiometry: Stoichiometry1617
participant stoichiometry: Stoichiometry1616
left: SmallMolecule11
left: Protein4337
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule14
right: Protein4340

Uptake of Noradrenaline
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1156
evidence: Evidence1155
xref: UnificationXref12475
xref: UnificationXref12474
left: SmallMolecule970
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule971

Degradation multiubiquitinated Cyclin A
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1153
xref: RelationshipXref1067
xref: UnificationXref12465
xref: UnificationXref12464
participant stoichiometry: Stoichiometry1615
left: Complex589
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein3409
right: Protein4336
right: Complex519

Ubiquitination of Cyclin A by APC/C:Cdc20 complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1152
EC number: 6.3.2.19
xref: UnificationXref12462
xref: RelationshipXref1066
xref: UnificationXref12463
participant stoichiometry: Stoichiometry1612
left: Complex588
left: Protein3409
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex589

Association of Cyclin A with the APC/C
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1151
xref: UnificationXref12459
xref: UnificationXref12460
left: Complex587
left: Complex519
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex588

Joining of adjacent Okazaki fragments
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1142
xref: UnificationXref12415
xref: UnificationXref12416
left: PhysicalEntity231
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity234

Removal of remaining Flap
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1140
xref: UnificationXref12410
xref: UnificationXref12409
left: Complex585
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex586

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q8LEW7
data source: Provenance1
name: U6 snRNA-associated Sm-like protein LSm1
name: Q8LEW7
name: LSM1_HUMAN
xref: UnificationXref15068
feature: FragmentFeature4459
cellular location: GO:0005829
comment: Reactome DB_ID: 4190455
display name: LSM1

Recruitment of Dna2 endonuclease
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1139
xref: UnificationXref12401
xref: UnificationXref12402
left: Protein4310
left: Complex583
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex584

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LJI0
data source: Provenance1
name: Q9LJI0
name: U6 snRNA-associated Sm-like protein LSm1
name: LSM1_HUMAN
xref: UnificationXref15070
feature: FragmentFeature4460
cellular location: GO:0005829
comment: Reactome DB_ID: 4190459
display name: LSM1

Formation of the Flap Intermediate
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1138
xref: UnificationXref12391
xref: UnificationXref12390
left: Complex581
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex582

Homologues of LSM1
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref15073
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4190462

Formation of Okazaki fragments
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1137
EC number: 2.7.7.7
xref: UnificationXref12387
xref: UnificationXref12388
left: Complex580
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex581

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q945P8
data source: Provenance1
name: Q945P8
name: U6 snRNA-associated Sm-like protein LSm1
name: LSM1_HUMAN
xref: UnificationXref15066
feature: FragmentFeature4458
cellular location: GO:0005829
comment: Reactome DB_ID: 4190453
display name: LSM1

Q0WU01
type: Protein
entity reference: Q0WU01
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: LSM3(2-102)
name: U6 snRNA-associated Sm-like protein LSm3
name: LSM3_HUMAN
xref: UnificationXref15061
feature: FragmentFeature4456
cellular location: GO:0005829
comment: Reactome DB_ID: 4190468
display name: LSM3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9C6K5
data source: Provenance1
name: LSM3(2-102)
name: Q9C6K5
name: U6 snRNA-associated Sm-like protein LSm3
name: LSM3_HUMAN
xref: UnificationXref15063
feature: FragmentFeature4457
cellular location: GO:0005829
comment: Reactome DB_ID: 4190472
display name: LSM3

Homologues of LSM3(2-102)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q0WU01
xref: UnificationXref15064
cellular location: GO:0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4190473

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9LMN4
data source: Provenance1
name: Q9LMN4
name: LSM3(2-102)
name: U6 snRNA-associated Sm-like protein LSm3
name: LSM3_HUMAN
xref: UnificationXref15059
feature: FragmentFeature4455
cellular location: GO:0005829
comment: Reactome DB_ID: 4190466
display name: LSM3

http://identifiers.org/pubmed/17891149
type: PublicationXref
id: 17891149
author: Fasshauer, D
author: Riedel, D
author: Jahn, R
author: Radhakrishnan, A
author: Stein, A
db: Pubmed
title: Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids
source: Nat Struct Mol Biol 14:904-11
year: 2007

Endosome acidification
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1184
xref: UnificationXref12725
xref: UnificationXref12724
left: SmallMolecule37
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule973

PDK1 attachment to plasma membrane
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1178
xref: UnificationXref12578
xref: UnificationXref12579
left: Protein3397
left: SmallMolecule972
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex594

GEFs activate Rho GTPase:GDP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1203
xref: UnificationXref12839
xref: UnificationXref12838
left: Complex604
left: SmallMolecule460
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex605
right: SmallMolecule486

p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1187
xref: UnificationXref12756
xref: UnificationXref12757
left: Complex602
left: SmallMolecule460
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex603
right: SmallMolecule486

HNRNPD-4
type: Protein
entity reference: F4JYK7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15122
feature: FragmentFeature4480
cellular location: GO:0005829
comment: Reactome DB_ID: 4191659
display name: F4JYK7

Dissociation of Rho GTP:GDP from GDI complex
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1205
xref: UnificationXref12908
xref: UnificationXref12909
left: Complex606
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: PhysicalEntity247
right: Complex607

HNRNPD-4
type: Protein
entity reference: Q8LDS6
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15124
feature: FragmentFeature4481
cellular location: GO:0005829
comment: Reactome DB_ID: 4191660
display name: Q8LDS6

GDIs block activation of Rho GTPase:GDP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1204
xref: UnificationXref12906
xref: UnificationXref12907
left: PhysicalEntity247
left: Complex604
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex606

HNRNPD-4
type: Protein
entity reference: Q0WNB9
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15126
feature: FragmentFeature4482
cellular location: GO:0005829
comment: Reactome DB_ID: 4191661
display name: Q0WNB9

HNRNPD-4
type: Protein
entity reference: Q9C652
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15128
feature: FragmentFeature4483
cellular location: GO:0005829
comment: Reactome DB_ID: 4191662
display name: Q9C652

HNRNPD-4
type: Protein
entity reference: Q8W4A6
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15130
feature: FragmentFeature4484
cellular location: GO:0005829
comment: Reactome DB_ID: 4191663
display name: Q8W4A6

HNRNPD-4
type: Protein
entity reference: Q949Z3
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15132
feature: FragmentFeature4485
cellular location: GO:0005829
comment: Reactome DB_ID: 4191664
display name: Q949Z3

HNRNPD-4
type: Protein
entity reference: Q9SU99
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15134
feature: FragmentFeature4486
cellular location: GO:0005829
comment: Reactome DB_ID: 4191665
display name: Q9SU99

HNRNPD-4
type: Protein
entity reference: Q9SSE0
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15136
feature: FragmentFeature4487
cellular location: GO:0005829
comment: Reactome DB_ID: 4191666
display name: Q9SSE0

HNRNPD-4
type: Protein
entity reference: O23288
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15138
feature: FragmentFeature4488
cellular location: GO:0005829
comment: Reactome DB_ID: 4191667
display name: O23288

Phosphorylation and activation of eIF4G by activated S6K1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1168
xref: UnificationXref12535
xref: UnificationXref12536
participant stoichiometry: Stoichiometry1627
participant stoichiometry: Stoichiometry1626
left: SmallMolecule11
left: Protein2957
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein4359
right: SmallMolecule14

HNRNPD-4
type: Protein
entity reference: F4JYK6
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15140
feature: FragmentFeature4489
cellular location: GO:0005829
comment: Reactome DB_ID: 4191668
display name: F4JYK6

Phosphorylation of Ribosomal protein S6 by activated S6K1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1167
xref: UnificationXref12532
xref: UnificationXref12533
participant stoichiometry: Stoichiometry1625
participant stoichiometry: Stoichiometry1624
left: SmallMolecule11
left: Protein3034
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein4356
right: SmallMolecule14

AMPK phosphorylates Raptor
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1173
xref: UnificationXref12564
xref: UnificationXref12565
participant stoichiometry: Stoichiometry1633
participant stoichiometry: Stoichiometry1634
left: SmallMolecule11
left: Protein4350
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein4372
right: SmallMolecule14

Phosphorylated AMPK binds AMP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1172
xref: UnificationXref12560
xref: UnificationXref12559
left: Complex592
left: SmallMolecule18
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex593

Arabidopsis thaliana
type: BioSource
xref: UnificationXref12

http://identifiers.org/pubmed/19501527
type: PublicationXref
id: 19501527
author: Cassel, SL
author: Sutterwala, FS
author: Joly, S
db: Pubmed
title: The NLRP3 inflammasome: a sensor of immune danger signals
source: Semin Immunol 21:194-8
year: 2009

Activation of PLC beta-1/4
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1223
xref: UnificationXref13006
xref: UnificationXref13007
left: Complex623
left: PhysicalEntity250
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex625

G-protein alpha subunit is inactivated
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1221
EC number: 3.6.5.1
EC number: 3.6.5.3
EC number: 3.6.5.2
EC number: 3.6.5.4
xref: UnificationXref13002
xref: UnificationXref13001
left: Complex623
left: SmallMolecule486
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex624
right: SmallMolecule460

G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1218
EC number: 3.6.5.1
EC number: 3.6.5.3
EC number: 3.6.5.2
EC number: 3.6.5.4
xref: UnificationXref12945
xref: UnificationXref12986
left: Complex617
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex620

G alpha (q) auto-inactivates by hydrolysing GTP to GDP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1216
EC number: 3.6.5.1
EC number: 3.6.5.3
EC number: 3.6.5.2
EC number: 3.6.5.4
xref: UnificationXref12963
xref: UnificationXref12962
left: Complex614
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex616

HNRNPD-4
type: Protein
entity reference: F4K4W6
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15104
feature: FragmentFeature4471
cellular location: GO:0005829
comment: Reactome DB_ID: 4191650
display name: F4K4W6

HNRNPD-4
type: Protein
entity reference: Q94A00
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15106
feature: FragmentFeature4472
cellular location: GO:0005829
comment: Reactome DB_ID: 4191651
display name: Q94A00

HNRNPD-4
type: Protein
entity reference: B9DGK8
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15102
feature: FragmentFeature4470
cellular location: GO:0005829
comment: Reactome DB_ID: 4191649
display name: B9DGK8

PIP2 hydrolysis
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1224
EC number: 3.1.4.11
xref: UnificationXref13009
xref: UnificationXref13008
left: SmallMolecule101
left: SmallMolecule48
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule103
right: SmallMolecule927

http://identifiers.org/pubmed/8535439
type: PublicationXref
id: 8535439
author: Tolan, DR
db: Pubmed
title: Molecular basis of hereditary fructose intolerance: mutations and polymorphisms in the human aldolase B gene
source: Hum Mutat 6:210-8
year: 1995

HNRNPD-4
type: Protein
entity reference: Q9SM01
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15112
feature: FragmentFeature4475
cellular location: GO:0005829
comment: Reactome DB_ID: 4191654
display name: Q9SM01

G alpha (s) auto-inactivates by hydrolysing GTP to GDP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1208
EC number: 3.6.5.1
EC number: 3.6.5.3
EC number: 3.6.5.2
EC number: 3.6.5.4
xref: UnificationXref12924
xref: UnificationXref12923
left: Complex608
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex609
right: SmallMolecule31

HNRNPD-4
type: Protein
entity reference: F4JFN7
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15114
feature: FragmentFeature4476
cellular location: GO:0005829
comment: Reactome DB_ID: 4191655
display name: F4JFN7

HNRNPD-4
type: Protein
entity reference: F4JV21
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15108
feature: FragmentFeature4473
cellular location: GO:0005829
comment: Reactome DB_ID: 4191652
display name: F4JV21

HNRNPD-4
type: Protein
entity reference: B5BRC9
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15110
feature: FragmentFeature4474
cellular location: GO:0005829
comment: Reactome DB_ID: 4191653
display name: B5BRC9

HNRNPD-4
type: Protein
entity reference: B9DHV1
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15120
feature: FragmentFeature4479
cellular location: GO:0005829
comment: Reactome DB_ID: 4191658
display name: B9DHV1

PLC beta-mediated PIP2 hydrolysis
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1215
xref: UnificationXref12959
xref: UnificationXref12960
left: SmallMolecule101
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule103
right: SmallMolecule458

PLC beta is activated by G alpha (q)
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1214
xref: UnificationXref12958
xref: UnificationXref12957
left: Complex614
left: PhysicalEntity250
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex615

HNRNPD-4
type: Protein
entity reference: Q9FM47
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15116
feature: FragmentFeature4477
cellular location: GO:0005829
comment: Reactome DB_ID: 4191656
display name: Q9FM47

G alpha (z) auto-inactivates by hydrolysing GTP to GDP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1212
EC number: 3.6.5.1
EC number: 3.6.5.3
EC number: 3.6.5.2
EC number: 3.6.5.4
xref: UnificationXref12945
xref: UnificationXref12950
left: Complex612
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex613

HNRNPD-4
type: Protein
entity reference: F4I906
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: AUF1 isoform p37
name: HNRNPD isoform 4
name: Heterogeneous nuclear ribonucleoprotein D0
name: HNRPD_HUMAN
xref: UnificationXref15118
feature: FragmentFeature4478
cellular location: GO:0005829
comment: Reactome DB_ID: 4191657
display name: F4I906

G alpha (i) auto-inactivates by hydrolysing GTP to GDP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1210
EC number: 3.6.5.1
EC number: 3.6.5.3
EC number: 3.6.5.2
EC number: 3.6.5.4
xref: UnificationXref12945
xref: UnificationXref12944
left: Complex610
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex611

SequenceSite5949
type: SequenceSite
position status: EQUAL
sequence position: 1290

SequenceSite5948
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5947
type: SequenceSite
position status: EQUAL
sequence position: 472

SequenceSite5946
type: SequenceSite
position status: EQUAL
sequence position: 1290

SequenceSite5945
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5944
type: SequenceSite
position status: EQUAL
sequence position: 472

SequenceSite5943
type: SequenceSite
position status: EQUAL
sequence position: 1290

SequenceSite5942
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5941
type: SequenceSite
position status: EQUAL
sequence position: 472

SequenceSite5940
type: SequenceSite
position status: EQUAL
sequence position: 1290

Inactivation of PLC beta
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1225
xref: UnificationXref13011
xref: UnificationXref13010
left: Complex625
left: SmallMolecule48
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex624
right: PhysicalEntity250
right: SmallMolecule31

N-linked glycosylation of WNTs
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1232
xref: UnificationXref13024
xref: UnificationXref13025
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

Retinoid isomerohydrolase isomero-hydrolyses retinyl esters to 11-cis-retinol
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1241
xref: UnificationXref13081
xref: UnificationXref13082
left: SmallMolecule977
left: SmallMolecule48
display name: RPE65 isomero-hydrolyses atREs to 11cROL
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule982
right: SmallMolecule987
right: SmallMolecule37

atRAL(membrane) is transported to atRAL(cytosol) by ABCA4
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1242
xref: UnificationXref13087
xref: UnificationXref13088
left: SmallMolecule11
left: SmallMolecule48
left: SmallMolecule988
display name: ABCA4 mediates atRAL transport
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule976
right: SmallMolecule14
right: SmallMolecule31

WNT ligands traffic to the Golgi
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1233
xref: UnificationXref13026
xref: UnificationXref13027
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

Oxidation of beta-carotene to all-trans-retinal
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1239
EC number: 1.14.99.36
xref: UnificationXref13048
xref: UnificationXref13047
participant stoichiometry: Stoichiometry1700
left: SmallMolecule975
left: SmallMolecule240
display name: BCMO1:Fe2+ oxidises betaC to atRAL
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule976

SequenceSite5957
type: SequenceSite
position status: EQUAL
sequence position: 556

NMT1/2 transfer MYS to GNAT1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1246
EC number: 2.3.1.97
xref: UnificationXref13144
xref: UnificationXref13143
left: SmallMolecule992
left: Protein4622
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein4633
right: SmallMolecule92

SequenceSite5956
type: SequenceSite
position status: EQUAL
sequence position: 1

GUCA binds Ca2+ to form GUCA:Ca2+
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1247
xref: UnificationXref13193
xref: UnificationXref13194
left: PhysicalEntity253
left: SmallMolecule104
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Complex630

SequenceSite5959
type: SequenceSite
position status: EQUAL
sequence position: 556

NRPE is a substrate for ABCA4
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1243
xref: UnificationXref13095
xref: UnificationXref13096
left: SmallMolecule11
left: SmallMolecule989
left: SmallMolecule48
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule990
right: SmallMolecule14
right: SmallMolecule31

SequenceSite5958
type: SequenceSite
position status: EQUAL
sequence position: 1

METAP1/2 demethylates GNAT1
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1245
EC number: 3.4.11
xref: UnificationXref13126
xref: UnificationXref13127
left: Protein4615
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule672
right: Protein4622

SequenceSite5953
type: SequenceSite
position status: EQUAL
sequence position: 472

SequenceSite5952
type: SequenceSite
position status: EQUAL
sequence position: 1290

SequenceSite5955
type: SequenceSite
position status: EQUAL
sequence position: 1290

SequenceSite5954
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5950
type: SequenceSite
position status: EQUAL
sequence position: 472

SequenceSite5951
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5929
type: SequenceSite
position status: EQUAL
sequence position: 472

SequenceSite5928
type: SequenceSite
position status: EQUAL
sequence position: 1290

SequenceSite5927
type: SequenceSite
position status: EQUAL
sequence position: 1

UniProt:Q94JW0
type: ProteinReference
xref: UnificationXref13894
organism: Arabidopsis thaliana

SequenceSite5922
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5921
type: SequenceSite
position status: EQUAL
sequence position: 1254

SequenceSite5920
type: SequenceSite
position status: EQUAL
sequence position: 783

SequenceSite5926
type: SequenceSite
position status: EQUAL
sequence position: 1254

SequenceSite5925
type: SequenceSite
position status: EQUAL
sequence position: 783

http://identifiers.org/pubmed/18690016
type: PublicationXref
id: 18690016
author: Schnetkamp, PP
author: Altimimi, HF
db: Pubmed
title: Na+/Ca2+-K+ exchangers (NCKX): functional properties and physiological roles
source: Channels (Austin) 1:62-9
year: 2007

SequenceSite5924
type: SequenceSite
position status: EQUAL
sequence position: 771

SequenceSite5923
type: SequenceSite
position status: EQUAL
sequence position: 1290

SequenceSite5939
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5938
type: SequenceSite
position status: EQUAL
sequence position: 472

SequenceSite5931
type: SequenceSite
position status: EQUAL
sequence position: 1290

SequenceSite5930
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5933
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5932
type: SequenceSite
position status: EQUAL
sequence position: 472

SequenceSite5935
type: SequenceSite
position status: EQUAL
sequence position: 472

SequenceSite5934
type: SequenceSite
position status: EQUAL
sequence position: 1290

SequenceSite5937
type: SequenceSite
position status: EQUAL
sequence position: 1290

SequenceSite5936
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2598
type: Stoichiometry
physical entity: PhysicalEntity401
stoichiometric coefficient: 1.0

Stoichiometry2599
type: Stoichiometry
physical entity: PhysicalEntity402
stoichiometric coefficient: 1.0

Stoichiometry2592
type: Stoichiometry
physical entity: Protein6657
stoichiometric coefficient: 1.0

Stoichiometry2593
type: Stoichiometry
physical entity: Protein6660
stoichiometric coefficient: 1.0

Stoichiometry2590
type: Stoichiometry
physical entity: PhysicalEntity400
stoichiometric coefficient: 1.0

Stoichiometry2591
type: Stoichiometry
physical entity: Protein6656
stoichiometric coefficient: 1.0

Stoichiometry2596
type: Stoichiometry
physical entity: Protein6665
stoichiometric coefficient: 1.0

Stoichiometry2597
type: Stoichiometry
physical entity: Protein6666
stoichiometric coefficient: 1.0

Stoichiometry2594
type: Stoichiometry
physical entity: Protein6663
stoichiometric coefficient: 1.0

Stoichiometry2595
type: Stoichiometry
physical entity: Protein6664
stoichiometric coefficient: 1.0

SequenceSite5903
type: SequenceSite
position status: EQUAL
sequence position: 1290

Homologues of N-seryl-glycosylphosphatidylinositolethanolamine-TREH
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q9SEH9
xref: UnificationXref22
cellular location: GO:0005886
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4184410

SequenceSite5904
type: SequenceSite
position status: EQUAL
sequence position: 771

Q9SEH9
type: Protein
entity reference: Q9SEH9
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: N-seryl-glycosylphosphatidylinositolethanolamine-TREH
name: trehalase
xref: UnificationXref15
feature: ModificationFeature1
feature: FragmentFeature1
cellular location: GO:0005886
comment: Reactome DB_ID: 4184400
display name: TREH

SequenceSite5901
type: SequenceSite
position status: EQUAL
sequence position: 1254

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: O22986
data source: Provenance1
name: N-seryl-glycosylphosphatidylinositolethanolamine-TREH
name: O22986
name: trehalase
xref: UnificationXref17
feature: FragmentFeature2
feature: ModificationFeature2
cellular location: GO:0005886
comment: Reactome DB_ID: 4184403
display name: TREH

SequenceSite5902
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5900
type: SequenceSite
position status: EQUAL
sequence position: 783

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FYG3
data source: Provenance1
name: Q9FYG3
name: SLC2A5
name: Solute carrier family 2, facilitated glucose transporter member 5
xref: UnificationXref39
feature: FragmentFeature6
cellular location: GO:0005886
comment: Reactome DB_ID: 4184414
display name: GLUT5

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:Q2V4B9
data source: Provenance1
name: SLC2A5
name: Q2V4B9
name: Solute carrier family 2, facilitated glucose transporter member 5
xref: UnificationXref41
feature: FragmentFeature7
cellular location: GO:0005886
comment: Reactome DB_ID: 4184415
display name: GLUT5

SequenceSite5909
type: SequenceSite
position status: EQUAL
sequence position: 771

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9FR49
data source: Provenance1
name: N-seryl-glycosylphosphatidylinositolethanolamine-TREH
name: Q9FR49
name: trehalase
xref: UnificationXref19
feature: FragmentFeature3
feature: ModificationFeature3
cellular location: GO:0005886
comment: Reactome DB_ID: 4184406
display name: TREH

SequenceSite5907
type: SequenceSite
position status: EQUAL
sequence position: 1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: Q9SU50
data source: Provenance1
name: N-seryl-glycosylphosphatidylinositolethanolamine-TREH
name: Q9SU50
name: trehalase
xref: UnificationXref21
feature: ModificationFeature4
feature: FragmentFeature4
cellular location: GO:0005886
comment: Reactome DB_ID: 4184409
display name: TREH

SequenceSite5908
type: SequenceSite
position status: EQUAL
sequence position: 1290

Homologues of SLC2A5
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Q0WVE9
xref: UnificationXref44
cellular location: GO:0005886
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 4184417

SequenceSite5905
type: SequenceSite
position status: EQUAL
sequence position: 783

Q0WVE9
type: Protein
entity reference: Q0WVE9
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: SLC2A5
name: Solute carrier family 2, facilitated glucose transporter member 5
xref: UnificationXref37
feature: FragmentFeature5
cellular location: GO:0005886
comment: Reactome DB_ID: 4184413
display name: GLUT5

SequenceSite5906
type: SequenceSite
position status: EQUAL
sequence position: 1254

Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
type: Pathway
data source: Provenance1
pathway component: Butyrate Response Factor1 (BRF1) Binds AU-rich Element in 3' UTR of mRNA
evidence: Evidence1439
xref: UnificationXref15270
xref: UnificationXref15269
pathway order: PathwayStep1417
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/9153422
type: PublicationXref
id: 9153422
author: Batelier, G
author: Soulié, S
author: Melki, R
author: Williams RC, Jr
db: Pubmed
title: Cytoplasmic chaperonin containing TCP-1: structural and functional characterization
source: Biochemistry 36:5817-26
year: 1997

SequenceSite5912
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5913
type: SequenceSite
position status: EQUAL
sequence position: 1290

SequenceSite5914
type: SequenceSite
position status: EQUAL
sequence position: 771

SequenceSite5915
type: SequenceSite
position status: EQUAL
sequence position: 783

MicroRNA (miRNA) Biogenesis
type: Pathway
data source: Provenance1
pathway component: Exportin complex translocates pre-miRNA to cytosol
pathway component: Exportin-5 recognizes 3' overhang of pre-miRNA
pathway component: Removal of miRNA passenger strand
pathway component: TemplateReaction37
evidence: Evidence1542
xref: UnificationXref17115
xref: UnificationXref17116
pathway order: PathwayStep1518
pathway order: PathwayStep1517
pathway order: PathwayStep1516
pathway order: PathwayStep1515
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

SequenceSite5910
type: SequenceSite
position status: EQUAL
sequence position: 783

SequenceSite5911
type: SequenceSite
position status: EQUAL
sequence position: 1254

SequenceSite5916
type: SequenceSite
position status: EQUAL
sequence position: 1254

SequenceSite5917
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5918
type: SequenceSite
position status: EQUAL
sequence position: 1290

SequenceSite5919
type: SequenceSite
position status: EQUAL
sequence position: 771

http://identifiers.org/pubmed/9811831
type: PublicationXref
id: 9811831
author: Tonks, NK
author: Batty, IH
author: Pass, I
author: Hemmings, BA
author: Myers, MP
author: van der Kaay, J
author: Downes, CP
author: Wigler, Michael H
author: Stolarov, JP
db: Pubmed
title: The lipid phosphatase activity of PTEN is critical for its tumor supressor function
source: Proc Natl Acad Sci U S A 95:13513-8
year: 1998

http://identifiers.org/pubmed/11584019
type: PublicationXref
id: 11584019
author: Soloway, PD
author: Roberts, CR
author: Overall, CM
author: Butler, GS
author: Morrison, CJ
author: Bigg, HF
db: Pubmed
title: Cellular activation of MMP-2 (gelatinase A) by MT2-MMP occurs via a TIMP-2-independent pathway
source: J Biol Chem 276:47402-10
year: 2001

Inhibition of replication initiation of damaged DNA by RB1/E2F1
type: Pathway
data source: Provenance1
pathway component: Detection of damage during initiation of DNA synthesis in S-phase
pathway component: PP2A mediated localization of RB1 protein in chromatin
evidence: Evidence1579
xref: UnificationXref17299
xref: UnificationXref17298
pathway order: PathwayStep1553
pathway order: PathwayStep1552
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

UniProt:F4K285
type: ProteinReference
xref: UnificationXref12188
organism: Arabidopsis thaliana

Stoichiometry2549
type: Stoichiometry
physical entity: Complex869
stoichiometric coefficient: 1.0

PublicationXref703
type: PublicationXref
author: Cox, MM
author: Nelson, DL
title: Lehninger - Principles of Biochemistry 4th Edn.
source: 690-750
year: 2005

PublicationXref704
type: PublicationXref
author: Michal, G
title: Biochemical Pathways - An Atlas of Biochemistry and Molecular Biology
source: 193-200
year: 1999

Stoichiometry2547
type: Stoichiometry
physical entity: Complex868
stoichiometric coefficient: 1.0

PublicationXref701
type: PublicationXref
author: Murray, RK
title: Harper's Biochemistry 25th Edn.
source: 137-48

UniProt:F4JQB6
type: ProteinReference
xref: UnificationXref14949
organism: Arabidopsis thaliana

Stoichiometry2548
type: Stoichiometry
physical entity: Complex568
stoichiometric coefficient: 1.0

Stoichiometry2545
type: Stoichiometry
physical entity: Protein6598
stoichiometric coefficient: 1.0

Stoichiometry2546
type: Stoichiometry
physical entity: Complex869
stoichiometric coefficient: 1.0

Stoichiometry2543
type: Stoichiometry
physical entity: Protein6594
stoichiometric coefficient: 1.0

PublicationXref705
type: PublicationXref
author: Metzler, DE
title: Biochemistry - The Chemical Reactions of Living Cells 2nd Edn.
source: 2:1018-84
year: 2003

Stoichiometry2544
type: Stoichiometry
physical entity: Protein6595
stoichiometric coefficient: 1.0

Stoichiometry2541
type: Stoichiometry
physical entity: Protein6592
stoichiometric coefficient: 1.0

Stoichiometry2542
type: Stoichiometry
physical entity: Protein6593
stoichiometric coefficient: 1.0

Stoichiometry2540
type: Stoichiometry
physical entity: Protein6591
stoichiometric coefficient: 1.0

PublicationXref700
type: PublicationXref
author: Nicholls, DG
author: Ferguson, SJ
title: Bioenergetics 3
source: 89-134
year: 2002

Stoichiometry2536
type: Stoichiometry
physical entity: Protein6577
stoichiometric coefficient: 1.0

Stoichiometry2537
type: Stoichiometry
physical entity: Protein6578
stoichiometric coefficient: 1.0

Stoichiometry2538
type: Stoichiometry
physical entity: Protein6579
stoichiometric coefficient: 1.0

(R)-(-)-Adrenaline
type: SmallMoleculeReference
name: (R)-(-)-Adnephrine
name: (R)-(-)-Epirenamine
name: L-Adrenaline
name: 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol [ChEBI:1942]
name: 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
name: (R)-(-)-Epinephrine
xref: UnificationXref18527

Stoichiometry2539
type: Stoichiometry
physical entity: Protein6582
stoichiometric coefficient: 1.0

cobalamin(III)
type: SmallMoleculeReference
name: cob(III)alamin [ChEBI:28911]
name: alpha-(5,6-dimethylbenzimidazolyl)cobamide
name: Cobalamin (III)
name: cobalamin(1+)
name: cob(III)alamin
name: Cbl
xref: UnificationXref5484

Stoichiometry2532
type: Stoichiometry
physical entity: Protein6575
stoichiometric coefficient: 1.0

Stoichiometry2533
type: Stoichiometry
physical entity: PhysicalEntity394
stoichiometric coefficient: 1.0

Stoichiometry2534
type: Stoichiometry
physical entity: Protein6576
stoichiometric coefficient: 1.0

1-acyl-sn-glycero-3-phospho-D-myo-inositol
type: SmallMoleculeReference
name: 1-Acyl-sn-glycero-3-phosphoinositol
name: 1-acyl-sn-glycero-3-phospho-D-myo-inositol [ChEBI:28914]
xref: UnificationXref2861

Stoichiometry2535
type: Stoichiometry
physical entity: PhysicalEntity395
stoichiometric coefficient: 1.0

Stoichiometry2530
type: Stoichiometry
physical entity: Complex864
stoichiometric coefficient: 1.0

Stoichiometry2531
type: Stoichiometry
physical entity: Protein4254
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/10092594
type: PublicationXref
id: 10092594
author: Jones, JM
author: Gould, SJ
author: Geraghty, MT
author: Nau, K
author: Erdmann, R
db: Pubmed
title: Identification of peroxisomal acyl-CoA thioesterases in yeast and humans
source: J Biol Chem 274:9216-23
year: 1999

Insulin receptor mediated signaling
type: Pathway
data source: Provenance1
pathway component: REACT 81064.9
pathway component: REACT 30654.10
evidence: Evidence1186
xref: RelationshipXref1079
xref: UnificationXref12728
xref: UnificationXref12729
pathway order: PathwayStep1165
pathway order: PathwayStep1167
display name: Signaling by Insulin receptor
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Stoichiometry2529
type: Stoichiometry
physical entity: Complex863
stoichiometric coefficient: 1.0

Stoichiometry2523
type: Stoichiometry
physical entity: Protein6563
stoichiometric coefficient: 2.0

Stoichiometry2524
type: Stoichiometry
physical entity: Complex866
stoichiometric coefficient: 6.0

Stoichiometry2521
type: Stoichiometry
physical entity: Protein6558
stoichiometric coefficient: 1.0

Stoichiometry2522
type: Stoichiometry
physical entity: Protein6559
stoichiometric coefficient: 1.0

Stoichiometry2527
type: Stoichiometry
physical entity: Protein6571
stoichiometric coefficient: 1.0

Stoichiometry2528
type: Stoichiometry
physical entity: Complex865
stoichiometric coefficient: 1.0

Stoichiometry2525
type: Stoichiometry
physical entity: Protein6566
stoichiometric coefficient: 1.0

Stoichiometry2526
type: Stoichiometry
physical entity: Protein6570
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/8672512
type: PublicationXref
id: 8672512
author: Horiuchi, S
author: Sano, H
author: Yoshida, M
author: Jinnouchi, Y
author: Higashi, T
author: Ikeda, K
author: Araki, T
author: Ueda, S
db: Pubmed
title: N (epsilon)-(carboxymethyl)lysine protein adduct is a major immunological epitope in proteins modified with advanced glycation end products of the Maillard reaction
source: Biochemistry 35:8075-83
year: 1996

Stoichiometry2520
type: Stoichiometry
physical entity: Protein6557
stoichiometric coefficient: 1.0

UnificationXref17109
type: UnificationXref
id: 4187456
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187456

UnificationXref17108
type: UnificationXref
id: 4187455
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187455

UnificationXref17107
type: UnificationXref
id: REACT_119942
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_119942.1

UnificationXref17106
type: UnificationXref
id: 426443
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=426443

UnificationXref17105
type: UnificationXref
id: 4187454
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187454

UnificationXref17104
type: UnificationXref
id: 4187453
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187453

Stoichiometry2519
type: Stoichiometry
physical entity: PhysicalEntity393
stoichiometric coefficient: 1.0

UnificationXref17103
type: UnificationXref
id: 4187452
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187452

Stoichiometry2518
type: Stoichiometry
physical entity: Protein6552
stoichiometric coefficient: 2.0

UnificationXref17102
type: UnificationXref
id: 4187451
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187451

UnificationXref17101
type: UnificationXref
id: 4187450
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187450

UnificationXref17100
type: UnificationXref
id: 4187449
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4187449

Stoichiometry2510
type: Stoichiometry
physical entity: PhysicalEntity235
stoichiometric coefficient: 1.0

Stoichiometry2511
type: Stoichiometry
physical entity: Protein6548
stoichiometric coefficient: 1.0

Stoichiometry2512
type: Stoichiometry
physical entity: Protein6549
stoichiometric coefficient: 1.0

2-acyl-sn-glycero-3-phosphoethanolamine [ChEBI:28936]
type: SmallMoleculeReference
name: 2-acyl-sn-glycero-3-phosphoethanolamine
xref: UnificationXref2715

Stoichiometry2513
type: Stoichiometry
physical entity: PhysicalEntity227
stoichiometric coefficient: 1.0

Stoichiometry2514
type: Stoichiometry
physical entity: Protein6550
stoichiometric coefficient: 1.0

NH4+
type: SmallMoleculeReference
name: NH4+ [ChEBI:28938]
xref: UnificationXref4646

Stoichiometry2515
type: Stoichiometry
physical entity: PhysicalEntity227
stoichiometric coefficient: 1.0

Stoichiometry2516
type: Stoichiometry
physical entity: PhysicalEntity227
stoichiometric coefficient: 1.0

Separation of Sister Chromatids
type: Pathway
data source: Provenance1
pathway component: Autocleavage of ESPL1 (Separase)
pathway component: Degradation of multiubiquitinated Securin
pathway component: Ubiquitination of Securin by phospho-APC/C:Cdc20 complex
evidence: Evidence1259
xref: UnificationXref13298
xref: UnificationXref13299
pathway order: PathwayStep1238
pathway order: PathwayStep1237
pathway order: PathwayStep1239
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: Arabidopsis thaliana

Stoichiometry2517
type: Stoichiometry
physical entity: Protein6551
stoichiometric coefficient: 1.0

Stoichiometry2508
type: Stoichiometry
physical entity: PhysicalEntity235
stoichiometric coefficient: 1.0

Stoichiometry2507
type: Stoichiometry
physical entity: Complex568
stoichiometric coefficient: 1.0

Stoichiometry2509
type: Stoichiometry
physical entity: Protein6547
stoichiometric coefficient: 1.0

Stoichiometry2586
type: Stoichiometry
physical entity: Protein6642
stoichiometric coefficient: 1.0

Stoichiometry2585
type: Stoichiometry
physical entity: Protein6639
stoichiometric coefficient: 1.0

Stoichiometry2584
type: Stoichiometry
physical entity: Protein6635
stoichiometric coefficient: 1.0

Stoichiometry2583
type: Stoichiometry
physical entity: Protein6631
stoichiometric coefficient: 1.0

Stoichiometry2582
type: Stoichiometry
physical entity: Protein6628
stoichiometric coefficient: 1.0

Stoichiometry2581
type: Stoichiometry
physical entity: Protein6622
stoichiometric coefficient: 1.0

Stoichiometry2580
type: Stoichiometry
physical entity: Protein6621
stoichiometric coefficient: 1.0

SequenceSite5982
type: SequenceSite
position status: EQUAL
sequence position: 77

SequenceSite5981
type: SequenceSite
position status: EQUAL
sequence position: 76

SequenceSite5984
type: SequenceSite
position status: EQUAL
sequence position: 153

SequenceSite5983
type: SequenceSite
position status: EQUAL
sequence position: 152

Stoichiometry2589
type: Stoichiometry
physical entity: Protein6653
stoichiometric coefficient: 1.0

Stoichiometry2588
type: Stoichiometry
physical entity: Protein6650
stoichiometric coefficient: 1.0

SequenceSite5980
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2587
type: Stoichiometry
physical entity: Protein6647
stoichiometric coefficient: 1.0

SequenceSite5989
type: SequenceSite
position status: EQUAL
sequence position: 380

SequenceSite5985
type: SequenceSite
position status: EQUAL
sequence position: 228

SequenceSite5986
type: SequenceSite
position status: EQUAL
sequence position: 229

SequenceSite5987
type: SequenceSite
position status: EQUAL
sequence position: 304

SequenceSite5988
type: SequenceSite
position status: EQUAL
sequence position: 305

Stoichiometry2573
type: Stoichiometry
physical entity: Protein3850
stoichiometric coefficient: 3.0

Stoichiometry2572
type: Stoichiometry
physical entity: Protein3409
stoichiometric coefficient: 4.0

Stoichiometry2575
type: Stoichiometry
physical entity: Protein3850
stoichiometric coefficient: 3.0

Stoichiometry2574
type: Stoichiometry
physical entity: Complex872
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/20593814
type: PublicationXref
id: 20593814
author: Thorpe, C
author: Bahnson, BJ
author: Daithankar, VN
author: Schaefer, SA
author: Dong, M
db: Pubmed
title: Structure of the human sulfhydryl oxidase augmenter of liver regeneration and characterization of a human mutation causing an autosomal recessive myopathy
source: Biochemistry 49:6737-45
year: 2010

Stoichiometry2571
type: Stoichiometry
physical entity: Protein3409
stoichiometric coefficient: 4.0

Stoichiometry2570
type: Stoichiometry
physical entity: Complex876
stoichiometric coefficient: 1.0

SequenceSite5995
type: SequenceSite
position status: EQUAL
sequence position: 608

SequenceSite5994
type: SequenceSite
position status: EQUAL
sequence position: 533

SequenceSite5993
type: SequenceSite
position status: EQUAL
sequence position: 532

SequenceSite5992
type: SequenceSite
position status: EQUAL
sequence position: 457

Stoichiometry2577
type: Stoichiometry
physical entity: Protein6611
stoichiometric coefficient: 1.0

SequenceSite5991
type: SequenceSite
position status: EQUAL
sequence position: 456

Stoichiometry2576
type: Stoichiometry
physical entity: Protein3850
stoichiometric coefficient: 3.0

SequenceSite5990
type: SequenceSite
position status: EQUAL
sequence position: 381

Stoichiometry2579
type: Stoichiometry
physical entity: PhysicalEntity399
stoichiometric coefficient: 1.0

Stoichiometry2578
type: Stoichiometry
physical entity: Protein6618
stoichiometric coefficient: 1.0

SequenceSite5998
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5999
type: SequenceSite
position status: EQUAL
sequence position: 908

SequenceSite5996
type: SequenceSite
position status: EQUAL
sequence position: 609

SequenceSite5997
type: SequenceSite
position status: EQUAL
sequence position: 684

Stoichiometry2560
type: Stoichiometry
physical entity: Protein3409
stoichiometric coefficient: 4.0

Stoichiometry2564
type: Stoichiometry
physical entity: PhysicalEntity397
stoichiometric coefficient: 1.0

Stoichiometry2563
type: Stoichiometry
physical entity: Complex876
stoichiometric coefficient: 1.0

Stoichiometry2562
type: Stoichiometry
physical entity: Protein6599
stoichiometric coefficient: 1.0

Stoichiometry2561
type: Stoichiometry
physical entity: Complex520
stoichiometric coefficient: 1.0

Stoichiometry2568
type: Stoichiometry
physical entity: Protein3409
stoichiometric coefficient: 4.0

Stoichiometry2567
type: Stoichiometry
physical entity: Protein3409
stoichiometric coefficient: 4.0

Stoichiometry2566
type: Stoichiometry
physical entity: Complex877
stoichiometric coefficient: 1.0

Stoichiometry2565
type: Stoichiometry
physical entity: Protein3409
stoichiometric coefficient: 4.0

SequenceSite5960
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5962
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry2569
type: Stoichiometry
physical entity: PhysicalEntity398
stoichiometric coefficient: 1.0

SequenceSite5961
type: SequenceSite
position status: EQUAL
sequence position: 556

SequenceSite5963
type: SequenceSite
position status: EQUAL
sequence position: 556

SequenceSite5964
type: SequenceSite
position status: EQUAL
sequence position: 2

UniProt:F4K2A2
type: ProteinReference
xref: UnificationXref5675
organism: Arabidopsis thaliana

SequenceSite5965
type: SequenceSite
position status: EQUAL
sequence position: 149

UniProt:F4K2A1
type: ProteinReference
xref: UnificationXref5681
organism: Arabidopsis thaliana

SequenceSite5966
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite5967
type: SequenceSite
position status: EQUAL
sequence position: 149

SequenceSite5968
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite5969
type: SequenceSite
position status: EQUAL
sequence position: 149

2,4-Dinitro-1-chlorobenzene
type: SmallMoleculeReference
name: 1-chloro-2,4-dinitrobenzene [ChEBI:34718]
name: DNCB
name: 1-Chloro-2,4-dinitrobenzol
name: 1-chloro-2,4-dinitrobenzene
name: Dncb
name: 6-Chloro-1,3-dinitrobenzene
name: Dinitrochlorobenzene
name: 1,3-Dinitro-4-chlorobenzene
name: Chlorodinitrobenzene
name: 2,4-Dinitrophenyl chloride
name: Cdnb
name: 4-Chloro-1,3-dinitrobenzene
name: 2,4-Dinitrochlorobenzene
xref: UnificationXref7174

Stoichiometry2551
type: Stoichiometry
physical entity: Complex872
stoichiometric coefficient: 1.0

Stoichiometry2550
type: Stoichiometry
physical entity: Protein6542
stoichiometric coefficient: 1.0

Stoichiometry2553
type: Stoichiometry
physical entity: Complex638
stoichiometric coefficient: 1.0

Stoichiometry2552
type: Stoichiometry
physical entity: Complex568
stoichiometric coefficient: 1.0

Stoichiometry2555
type: Stoichiometry
physical entity: PhysicalEntity396
stoichiometric coefficient: 1.0

Stoichiometry2554
type: Stoichiometry
physical entity: Protein4336
stoichiometric coefficient: 1.0

Stoichiometry2557
type: Stoichiometry
physical entity: Protein3409
stoichiometric coefficient: 4.0

Stoichiometry2556
type: Stoichiometry
physical entity: Complex874
stoichiometric coefficient: 1.0

Stoichiometry2559
type: Stoichiometry
physical entity: Protein3409
stoichiometric coefficient: 4.0

SequenceSite5973
type: SequenceSite
position status: EQUAL
sequence position: 152

Stoichiometry2558
type: Stoichiometry
physical entity: Complex873
stoichiometric coefficient: 1.0

SequenceSite5972
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5971
type: SequenceSite
position status: EQUAL
sequence position: 149

SequenceSite5970
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite5976
type: SequenceSite
position status: EQUAL
sequence position: 1

UniProt:Q94KE0
type: ProteinReference
xref: UnificationXref18346
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/12671646
type: PublicationXref
id: 12671646
author: Chao, MV
db: Pubmed
title: Neurotrophins and their receptors: a convergence point for many signalling pathways
source: Nat Rev Neurosci 4:299-309
year: 2003

SequenceSite5977
type: SequenceSite
position status: EQUAL
sequence position: 152

SequenceSite5974
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5975
type: SequenceSite
position status: EQUAL
sequence position: 152

SequenceSite5978
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite5979
type: SequenceSite
position status: EQUAL
sequence position: 76

UnificationXref13948
type: UnificationXref
id: 4183023
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183023

UnificationXref13949
type: UnificationXref
id: Q6DBN0
db: UniProt

UnificationXref13946
type: UnificationXref
id: 4183021
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183021

UnificationXref13947
type: UnificationXref
id: Q6NLZ3
db: UniProt

UnificationXref13956
type: UnificationXref
id: CHEBI:52572
db: ChEBI

UnificationXref13955
type: UnificationXref
id: REACT_4171
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4171.2

UnificationXref13954
type: UnificationXref
id: 162768
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=162768

UnificationXref13953
type: UnificationXref
id: REACT_114989
db: Reactome
id version: 8
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_114989.8

UnificationXref13952
type: UnificationXref
id: 4183028
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183028

UnificationXref13951
type: UnificationXref
id: 4183026
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183026

UnificationXref13950
type: UnificationXref
id: 4183025
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183025

http://identifiers.org/pubmed/9536209
type: PublicationXref
id: 9536209
author: Clarke, D
author: Cunningham, SK
author: Fearon, U
author: McKenna, TJ
db: Pubmed
title: A critical review of the origin and control of adrenal androgens
source: Baillieres Clin Obstet Gynaecol 11:229-48
year: 1997

UnificationXref13957
type: UnificationXref
id: 162856
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=162856

UnificationXref13958
type: UnificationXref
id: REACT_4602
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4602.2

UnificationXref13959
type: UnificationXref
id: 162743
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=162743

UnificationXref13965
type: UnificationXref
id: CHEBI:16038
db: ChEBI

UnificationXref13964
type: UnificationXref
id: REACT_32115
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_32115.10

UnificationXref13967
type: UnificationXref
id: REACT_3657
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3657.3

UnificationXref13966
type: UnificationXref
id: 162803
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=162803

UnificationXref13961
type: UnificationXref
id: B3H6K1
db: UniProt

UnificationXref13960
type: UnificationXref
id: REACT_2982
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2982.1

UnificationXref13963
type: UnificationXref
id: 4182943
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182943

UnificationXref13962
type: UnificationXref
id: 4182941
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4182941

UniProt:Q9C6A9
type: ProteinReference
xref: UnificationXref12258
organism: Arabidopsis thaliana

UnificationXref13968
type: UnificationXref
id: CHEBI:53056
db: ChEBI

UnificationXref13969
type: UnificationXref
id: 162793
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=162793

UnificationXref13974
type: UnificationXref
id: REACT_2468
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2468.1

UnificationXref13973
type: UnificationXref
id: 162843
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=162843

UnificationXref13972
type: UnificationXref
id: REACT_2701
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2701.2

UnificationXref13971
type: UnificationXref
id: 162777
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=162777

UnificationXref13978
type: UnificationXref
id: REACT_99847
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_99847.9

UnificationXref13977
type: UnificationXref
id: 4183004
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183004

UnificationXref13976
type: UnificationXref
id: 4183002
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183002

UnificationXref13975
type: UnificationXref
id: F4JD48
db: UniProt

UnificationXref13970
type: UnificationXref
id: REACT_3849
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3849.2

UnificationXref13979
type: UnificationXref
id: GO:0071458
db: GENE ONTOLOGY

UnificationXref13983
type: UnificationXref
id: CHEBI:53058
db: ChEBI

UnificationXref13982
type: UnificationXref
id: REACT_5855
db: Reactome
id version: 4
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5855.4

UnificationXref13985
type: UnificationXref
id: REACT_4805
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4805.1

UnificationXref13984
type: UnificationXref
id: 162848
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=162848

UnificationXref13987
type: UnificationXref
id: 162872
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=162872

UnificationXref13986
type: UnificationXref
id: CHEBI:16214
db: ChEBI

UnificationXref13989
type: UnificationXref
id: O65394
db: UniProt

UnificationXref13988
type: UnificationXref
id: REACT_3693
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3693.3

UnificationXref13981
type: UnificationXref
id: 162681
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=162681

UnificationXref13980
type: UnificationXref
id: CHEBI:15809
db: ChEBI

http://identifiers.org/pubmed/11606068
type: PublicationXref
id: 11606068
author: Lorkowski, S
author: Rust, S
author: Engel, T
author: Berger, G
author: Assmann, G
author: Cullen, P
author: Lueken, A
author: Schlüter, B
db: Pubmed
title: The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages
source: Biochem Biophys Res Commun 288:483-8
year: 2001

UnificationXref13991
type: UnificationXref
id: Q6NKT6
db: UniProt

UnificationXref6312
type: UnificationXref
id: REACT_5535
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5535.2

UnificationXref13992
type: UnificationXref
id: 4183034
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183034

UnificationXref6311
type: UnificationXref
id: 29676
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29676

UnificationXref6310
type: UnificationXref
id: CHEBI:17672
db: ChEBI

UnificationXref13990
type: UnificationXref
id: 4183032
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183032

UnificationXref13999
type: UnificationXref
id: F4K887
db: UniProt

UnificationXref6319
type: UnificationXref
id: 4177104
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177104

UnificationXref13997
type: UnificationXref
id: 162684
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=162684

UnificationXref6318
type: UnificationXref
id: 4177102
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177102

UnificationXref13998
type: UnificationXref
id: REACT_5330
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5330.2

UnificationXref6317
type: UnificationXref
id: 4177101
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177101

UnificationXref13995
type: UnificationXref
id: REACT_96422
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_96422.9

UnificationXref6316
type: UnificationXref
id: O50039
db: UniProt

UnificationXref13996
type: UnificationXref
id: CHEBI:53059
db: ChEBI

UnificationXref6315
type: UnificationXref
id: REACT_2266
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2266.2

UnificationXref13993
type: UnificationXref
id: 4183035
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183035

UnificationXref6314
type: UnificationXref
id: 113567
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113567

UnificationXref13994
type: UnificationXref
id: 4183037
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4183037

UnificationXref6313
type: UnificationXref
id: CHEBI:16349
db: ChEBI

http://identifiers.org/pubmed/20060739
type: PublicationXref
id: 20060739
author: Sheftel, Alex
author: Stehling, Oliver
author: Lill, R
db: Pubmed
title: Iron-sulfur proteins in health and disease
source: Trends Endocrinol. Metab. 21:302-14
year: 2010

http://identifiers.org/pubmed/10548110
type: PublicationXref
id: 10548110
author: Lukas, J
author: Kramer, E
author: Peters, JM
author: Lindeneg, C
author: Santoni-Rugiu, E
author: Sorensen, CS
author: Lukas, C
db: Pubmed
title: Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex
source: Nature 401:815-8
year: 1999

UnificationXref6321
type: UnificationXref
id: 29968
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29968

UnificationXref6320
type: UnificationXref
id: REACT_102870
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_102870.9

UnificationXref6323
type: UnificationXref
id: CHEBI:15682
db: ChEBI

UnificationXref6322
type: UnificationXref
id: REACT_3861
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3861.3

UnificationXref6329
type: UnificationXref
id: 4177123
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177123

UnificationXref6328
type: UnificationXref
id: 4177121
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177121

UnificationXref6325
type: UnificationXref
id: REACT_5577
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5577.1

UnificationXref6324
type: UnificationXref
id: 34575
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=34575

UnificationXref6327
type: UnificationXref
id: 4177120
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177120

UnificationXref6326
type: UnificationXref
id: Q9SZX3
db: UniProt

UniProt:Q9C5Y9
type: ProteinReference
xref: UnificationXref9023
organism: Arabidopsis thaliana

UniProt:Q9C5Y4
type: ProteinReference
xref: UnificationXref13207
organism: Arabidopsis thaliana

UniProt:Q9C5Y2
type: ProteinReference
xref: UnificationXref6829
organism: Arabidopsis thaliana

http://identifiers.org/pubmed/11435397
type: PublicationXref
id: 11435397
author: Allikmets, R
author: Dean, M
author: Rzhetsky, A
db: Pubmed
title: The human ATP-binding cassette (ABC) transporter superfamily
source: Genome Res 11:1156-66
year: 2001

http://identifiers.org/pubmed/183599
type: PublicationXref
id: 183599
author: Hers, HG
db: Pubmed
title: The control of glycogen metabolism in the liver
source: Annu Rev Biochem 45:167-89
year: 1976

UniProt:Q9C5Z3
type: ProteinReference
xref: UnificationXref9008
organism: Arabidopsis thaliana

UniProt:Q9C5Z1
type: ProteinReference
xref: UnificationXref8987
organism: Arabidopsis thaliana

UnificationXref6301
type: UnificationXref
id: 4193347
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4193347

UniProt:Q9C5Z2
type: ProteinReference
xref: UnificationXref8974
organism: Arabidopsis thaliana

UnificationXref6300
type: UnificationXref
id: 4193330
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4193330

UnificationXref6303
type: UnificationXref
id: 4193351
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4193351

UnificationXref6302
type: UnificationXref
id: 4193349
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4193349

UnificationXref6305
type: UnificationXref
id: 4193353
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4193353

UnificationXref6304
type: UnificationXref
id: 4193352
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4193352

UnificationXref6307
type: UnificationXref
id: REACT_133490
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_133490.5

UnificationXref6306
type: UnificationXref
id: 4193355
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4193355

UnificationXref6309
type: UnificationXref
id: REACT_137968
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_137968.5

UnificationXref6308
type: UnificationXref
id: 4199896
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199896

UnificationXref6357
type: UnificationXref
id: REACT_4905
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4905.2

UnificationXref6358
type: UnificationXref
id: Q9S795
db: UniProt

UnificationXref6359
type: UnificationXref
id: 4177480
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177480

UnificationXref6353
type: UnificationXref
id: 31311
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=31311

UniProt:Q9C680
type: ProteinReference
xref: UnificationXref2983
organism: Arabidopsis thaliana

UnificationXref6354
type: UnificationXref
id: REACT_4362
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4362.2

UnificationXref6355
type: UnificationXref
id: CHEBI:16244
db: ChEBI

UnificationXref6356
type: UnificationXref
id: 31369
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=31369

UnificationXref6350
type: UnificationXref
id: 4199405
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199405

UniProt:Q9C5W3
type: ProteinReference
xref: UnificationXref5642
organism: Arabidopsis thaliana

UnificationXref6351
type: UnificationXref
id: REACT_97366
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_97366.9

UnificationXref6352
type: UnificationXref
id: CHEBI:18020
db: ChEBI

UniProt:Q6Y657
type: ProteinReference
xref: UnificationXref5067
organism: Arabidopsis thaliana

UnificationXref6368
type: UnificationXref
id: CHEBI:17431
db: ChEBI

UnificationXref6369
type: UnificationXref
id: 351164
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=351164

UnificationXref6366
type: UnificationXref
id: 4199411
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199411

UnificationXref6367
type: UnificationXref
id: REACT_159771
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_159771.3

UnificationXref6364
type: UnificationXref
id: 4177488
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177488

UnificationXref6365
type: UnificationXref
id: REACT_156962
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_156962.3

UnificationXref6362
type: UnificationXref
id: 4177485
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177485

UnificationXref6363
type: UnificationXref
id: 4177486
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177486

UnificationXref6360
type: UnificationXref
id: Q9STS1
db: UniProt

UnificationXref6361
type: UnificationXref
id: 4177484
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177484

UniProt:Q9C5X8
type: ProteinReference
xref: UnificationXref5848
organism: Arabidopsis thaliana

UnificationXref6335
type: UnificationXref
id: 4177108
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177108

UnificationXref6336
type: UnificationXref
id: O23637
db: UniProt

UnificationXref6337
type: UnificationXref
id: 4177110
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177110

UnificationXref6338
type: UnificationXref
id: Q9LEU8
db: UniProt

UnificationXref6339
type: UnificationXref
id: 4177112
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177112

UniProt:Q9C5U3
type: ProteinReference
xref: UnificationXref10081
organism: Arabidopsis thaliana

UnificationXref6330
type: UnificationXref
id: REACT_110988
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_110988.9

UnificationXref6331
type: UnificationXref
id: CHEBI:16467
db: ChEBI

UnificationXref6332
type: UnificationXref
id: 29468
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29468

UnificationXref6333
type: UnificationXref
id: REACT_2911
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2911.2

UnificationXref6334
type: UnificationXref
id: Q94AP1
db: UniProt

UnificationXref6348
type: UnificationXref
id: 4177159
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177159

UnificationXref6349
type: UnificationXref
id: REACT_30708
db: Reactome
id version: 10
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_30708.10

UnificationXref6346
type: UnificationXref
id: Q84UC7
db: UniProt

UnificationXref6347
type: UnificationXref
id: 4177157
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177157

UnificationXref13901
type: UnificationXref
id: 4199739
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4199739

UnificationXref13900
type: UnificationXref
id: REACT_95055
db: Reactome
id version: 9
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_95055.9

UnificationXref6340
type: UnificationXref
id: 4177113
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177113

UnificationXref6341
type: UnificationXref
id: 4177114
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177114

UnificationXref6344
type: UnificationXref
id: 29498
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29498

UnificationXref6345
type: UnificationXref
id: REACT_5017
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5017.2

UnificationXref6342
type: UnificationXref
id: 4177116
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4177116

UnificationXref6343
type: UnificationXref
id: REACT_114192
db: Reactome
id version: 8
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_114192.8

UnificationXref6398
type: UnificationXref
id: 4188150
db: Reactome Database ID Release 45
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=4188150