MODEL7743608569
type: SBMLModel
parameter: metaid_0000070
species: metaid_0000103
parameter: metaid_0000004
parameter: metaid_0000039
parameter: metaid_0000032
reaction: metaid_0000177
parameter: metaid_0000051
species: metaid_0000104
parameter: metaid_0000086
reaction: metaid_0000146
parameter: metaid_0000018
species: metaid_0000140
parameter: metaid_0000046
parameter: metaid_0000065
parameter: metaid_0000079
reaction: metaid_0000172
parameter: metaid_0000013
parameter: metaid_0000058
parameter: metaid_0000041
compartment: metaid_0000099
reaction: metaid_0000151
species: metaid_0000136
parameter: metaid_0000095
species: metaid_0000118
parameter: metaid_0000093
parameter: metaid_0000027
parameter: metaid_0000020
reaction: metaid_0000165
parameter: metaid_0000074
species: metaid_0000133
reaction: metaid_0000169
species: metaid_0000114
parameter: metaid_0000006
parameter: metaid_0000034
reaction: metaid_0000179
species: metaid_0000121
parameter: metaid_0000053
species: metaid_0000106
parameter: metaid_0000088
reaction: metaid_0000148
species: metaid_0000142
species: metaid_0000111
parameter: metaid_0000067
species: metaid_0000130
reaction: metaid_0000160
species: metaid_0000102
parameter: metaid_0000036
reaction: metaid_0000174
parameter: metaid_0000083
parameter: metaid_0000081
parameter: metaid_0000015
reaction: metaid_0000171
parameter: metaid_0000043
reaction: metaid_0000153
parameter: metaid_0000062
species: metaid_0000138
parameter: metaid_0000097
parameter: metaid_0000060
length unit: length
reaction: metaid_0000157
parameter: metaid_0000029
parameter: metaid_0000022
parameter: metaid_0000048
reaction: metaid_0000167
parameter: metaid_0000076
reaction: metaid_0000183
notes: NFkB model M(24,45,62) This is a model of NFkB pathway functioning from hierarchy of models of decreasing complexity, created to demonstrate application of model reduction methods proposed in Radulescu O, Gorban A., Zinovyev A., Lilienbaum. A. Robust simplifications of multiscale models in systems biology. Manuscript submitted. The models are provided in CellDesigner v3.5 format. The name of the model M(x,y,z) should be deciphered as following: x - number of species y - number of reactions z - number of parameters Simulation protocol: The model can be simulated in CellDesigner directly, or in any simulator supporting events. The simulation period should be set up in 40 hours (t=144000 sec). The 'signal' event applies signal to the pathway at the moment t=20 hours=72000 sec. For additional information please contact Andrei.Zinovyev at curie.fr This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not.. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
reaction: metaid_0000181
parameter: metaid_0000008
species: metaid_0000123
parameter: metaid_0000055
species: metaid_0000117
parameter: metaid_0000090
parameter: metaid_0000024
parameter: metaid_0000069
reaction: metaid_0000162
species: metaid_0000101
species: metaid_0000113
parameter: metaid_0000003

metaid_0000070
type: Parameter
constant: true
value: 0.055

metaid_0000103
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: sa438_degraded

metaid_0000098
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

metaid_0000004
type: Parameter
constant: true
value: 1.25E-4

metaid_0000039
type: Parameter
constant: true
value: 0.1

metaid_0000032
type: Parameter
constant: true
value: 0.01

metaid_0000177
type: Reaction
kinetic law: 861688
product: 861676
reactant: 861664
reactant: 861652
fast: false
reversible: false

861676
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000131

metaid_0000131
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: NFkB:IkB_alpha

metaid_0000099
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0
name: nucleus

861664
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000101

metaid_0000101
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: IkB_alpha

861652
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000132

metaid_0000132
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: NFkB

metaid_0000051
type: Parameter
constant: true
value: 6.4E-5

metaid_0000104
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: p50

metaid_0000086
type: Parameter
constant: true
value: 8.0E-13

metaid_0000146
type: Reaction
kinetic law: 860344
product: 860332
reactant: 860320
reactant: 860308
fast: false
reversible: false

860332
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000139

metaid_0000139
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: PromIkBa:RNAP3:FTAz:p50p65:IkB_alpha

860320
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000138

metaid_0000138
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: IkBa:RNAP3:FTAz:p50p65

860308
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000101

metaid_0000018
type: Parameter
constant: true
value: 0.0

metaid_0000140
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000099
name: p65

metaid_0000046
type: Parameter
constant: true
value: 0.01

metaid_0000065
type: Parameter
constant: true
value: 0.62

metaid_0000079
type: Parameter
constant: true
value: 0.62

metaid_0000172
type: Reaction
kinetic law: 861472
product: 861460
reactant: 861448
fast: false
reversible: false

861460
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000117

metaid_0000117
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: IKKn

861448
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000119

metaid_0000119
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: IKK

metaid_0000013
type: Parameter
constant: true
value: 1.25E-4

metaid_0000058
type: Parameter
constant: true
value: 10.0

metaid_0000041
type: Parameter
constant: true
value: 0.06

metaid_0000151
type: Reaction
kinetic law: 860608
product: 860596
reactant: 860584
fast: false
reversible: false

860596
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000102

metaid_0000102
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: csa17_degraded

860584
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000132

metaid_0000136
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: PromIkBa:RNAP3:p50p65

metaid_0000095
type: Parameter
constant: true
value: 0.0061
name: =kf68/kf64

metaid_0000118
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: sa20_degraded

metaid_0000093
type: Parameter
constant: true
value: 2.2925E-7
name: =k36*k39*P0*k34*kf68/(k37*kf64*(k38+k39))

metaid_0000027
type: Parameter
constant: true
value: 0.5

metaid_0000020
type: Parameter
constant: true
value: 8.0E-5

metaid_0000165
type: Reaction
kinetic law: 861160
product: 861148
reactant: 861136
fast: false
reversible: false

861148
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000116

metaid_0000116
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: IKKa

861136
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000130

metaid_0000130
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: IKKa:IKB_alpha

metaid_0000074
type: Parameter
constant: true
value: 8.0E-13

metaid_0000133
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 6.66666666666667E-6
in compartment: metaid_0000099
name: PromIkBa:RNAP3

metaid_0000169
type: Reaction
kinetic law: 861340
product: 861328
product: 861316
reactant: 861304
fast: false
reversible: false

861328
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000111

metaid_0000111
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: mRNAA20

861316
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000112

metaid_0000112
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: A20

861304
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000111

metaid_0000114
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: IKKi

metaid_0000006
type: Parameter
constant: true
value: 0.1

metaid_0000034
type: Parameter
constant: true
value: 10.0

metaid_0000179
type: Reaction
kinetic law: 861760
product: 861748
reactant: 861736
fast: false
reversible: false

861748
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000121

metaid_0000121
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: sa97_degraded

861736
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000112

metaid_0000053
type: Parameter
constant: true
value: 1.0E-4

metaid_0000106
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: sa9_degraded

metaid_0000088
type: Parameter
constant: true
value: 8.0E-13

metaid_0000148
type: Reaction
kinetic law: 860440
product: 860428
product: 860416
reactant: 860404
fast: false
reversible: false

860428
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000131

860416
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000134

metaid_0000134
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: PromIkBa:RNAP3:FTAz

860404
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000139

metaid_0000142
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: IkBp50p65

metaid_0000067
type: Parameter
constant: true
value: 0.62

metaid_0000160
type: Reaction
kinetic law: 860980
modifier: 860968
product: 860956
reactant: 860944
fast: false
reversible: false

860956
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000111

860944
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000110

metaid_0000110
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: A20

metaid_0000036
type: Parameter
constant: true
value: 5.0E-4

metaid_0000174
type: Reaction
kinetic law: 861568
product: 861556
reactant: 861544
reactant: 861532
fast: false
reversible: false

861556
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000130

861544
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000116

861532
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000108

metaid_0000108
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: IkB_alpha

metaid_0000083
type: Parameter
constant: true
value: 18.4

metaid_0000081
type: Parameter
constant: true
value: 18.4

metaid_0000015
type: Parameter
constant: true
value: 0.5

metaid_0000171
type: Reaction
kinetic law: 861436
modifier: 861424
product: 861412
reactant: 861400
fast: false
reversible: false

861412
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000114

861400
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000116

metaid_0000043
type: Parameter
constant: true
value: 0.02

metaid_0000153
type: Reaction
kinetic law: 860704
product: 860692
reactant: 860680
fast: false
reversible: false

860692
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000103

860680
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000104

metaid_0000062
type: Parameter
constant: true
value: 0.001

metaid_0000097
type: Parameter
constant: true
value: 1.0E-10

metaid_0000060
type: Parameter
constant: true
value: 0.025

metaid_0000157
type: Reaction
kinetic law: 860848
product: 860836
reactant: 860824
fast: false
reversible: false

860836
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000109

metaid_0000109
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: sa12_degraded

860824
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000125

metaid_0000125
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: mRNAIKB_alpha

metaid_0000029
type: Parameter
constant: true
value: 5.0E-4

metaid_0000022
type: Parameter
constant: true
value: 4.0E-4

metaid_0000048
type: Parameter
constant: true
value: 5.0E-5

metaid_0000167
type: Reaction
kinetic law: 861256
product: 861244
product: 861232
reactant: 861220
fast: false
reversible: false

861244
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000116

861232
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000129

metaid_0000129
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: NFkB

861220
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000128

metaid_0000128
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: NFkB:IKKa:Ikb_alpha

metaid_0000076
type: Parameter
constant: true
value: 8.0E-13

metaid_0000183
type: Reaction
kinetic law: 861904
product: 861892
reactant: 861880
fast: false
reversible: false

861892
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000124

metaid_0000124
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: csa9_degraded

861880
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000131

metaid_0000181
type: Reaction
kinetic law: 861832
product: 861820
reactant: 861808
fast: false
reversible: false

861820
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000122

metaid_0000122
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: csa21_degraded

861808
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000129

metaid_0000008
type: Parameter
constant: true
value: 1.25E-4

metaid_0000123
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: csa18_degraded

metaid_0000055
type: Parameter
constant: true
value: 0.0053

metaid_0000090
type: Parameter
constant: true
value: 2.0E-4

metaid_0000024
type: Parameter
constant: true
value: 5.0E-7

metaid_0000069
type: Parameter
constant: true
value: 18.4

metaid_0000162
type: Reaction
kinetic law: 861052
product: 861040
reactant: 861028
fast: false
reversible: false

861040
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000129

861028
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000127

metaid_0000127
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: NFkB:IkB_alpha

metaid_0000113
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: sa444_degraded

metaid_0000003
type: Parameter
constant: false
value: 0.0

metaid_0000038
type: Parameter
constant: true
value: 5.0E-4

metaid_0000120
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: sa96_degraded

metaid_0000031
type: Parameter
constant: true
value: 4.0E-4

metaid_0000176
type: Reaction
kinetic law: 861640
product: 861628
reactant: 861616
fast: false
reversible: false

861628
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000127

861616
type: SpeciesReference
stoichiometry: 5.0
species: metaid_0000131

metaid_0000050
type: Parameter
constant: true
value: 1.3E-4

metaid_0000085
type: Parameter
constant: true
value: 0.0038

metaid_0000145
type: Reaction
kinetic law: 860296
product: 860284
reactant: 860272
reactant: 860260
fast: false
reversible: false

860284
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000136

860272
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000133

860260
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000132

metaid_0000017
type: Parameter
constant: true
value: 0.5

metaid_0000010
type: Parameter
constant: true
value: 0.1

metaid_0000045
type: Parameter
constant: true
value: 0.6

metaid_0000155
type: Reaction
kinetic law: 860776
product: 860764
reactant: 860752
fast: false
reversible: false

860764
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000106

860752
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000105

metaid_0000105
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: p65

metaid_0000064
type: Parameter
constant: true
value: 2.0E-4

metaid_0000159
type: Reaction
kinetic law: 860932
product: 860920
product: 860908
reactant: 860896
fast: false
reversible: false

860920
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000125

860908
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000108

860896
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000125

metaid_0000078
type: Parameter
constant: true
value: 4.8E-4

metaid_0000184
type: Event
event assignment: 861941
delay: 861929
trigger: 861917
use values from trigger time: true
name: signal

861917
type: Trigger
persistant: true
initial value: true

metaid_0000012
type: Parameter
constant: true
value: 0.1

metaid_0000057
type: Parameter
constant: true
value: 6.4E-5

metaid_0000040
type: Parameter
constant: true
value: 0.006

metaid_0000137
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: PromIkBa:RNAP3:p50p65:IkBa

metaid_0000150
type: Reaction
modifier: 860548
product: 860512
modifier: 860560
modifier: 860536
modifier: 860524
reversible: false
reactant: 860500
kinetic law: 860572
fast: false

860512
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000126

metaid_0000126
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: ActivePRaseonIkB_alpha

860500
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000135

metaid_0000135
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: InactivePRaseonIkB_alpha

metaid_0000094
type: Parameter
constant: true
value: 6.7E-8
name: =k39*kr66*k70*P0/(k37*kf66*(k38+k39))

metaid_0000092
type: Parameter
constant: true
value: 7.07E-5
name: =k43*k45*P0 / k46

metaid_0000026
type: Parameter
constant: true
value: 1.0E-4

metaid_0000164
type: Reaction
kinetic law: 861124
product: 861112
reactant: 861100
fast: false
reversible: false

861112
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000118

861100
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000116

metaid_0000073
type: Parameter
constant: true
value: 0.0038

metaid_0000071
type: Parameter
constant: true
value: 18.4

metaid_0000115
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: sa19_degraded

metaid_0000168
type: Reaction
kinetic law: 861292
product: 861280
reactant: 861268
fast: false
reversible: false

861280
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000113

861268
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000114

metaid_0000005
type: Parameter
constant: true
value: 1.0E-5

metaid_0000033
type: Parameter
constant: true
value: 0.0

metaid_0000178
type: Reaction
kinetic law: 861724
product: 861712
reactant: 861700
fast: false
reversible: false

861712
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000120

861700
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000111

metaid_0000059
type: Parameter
constant: true
value: 1.0E-4

metaid_0000052
type: Parameter
constant: true
value: 10.0

metaid_0000143
type: Reaction
kinetic law: 860200
product: 860188
reactant: 860176
reactant: 860164
fast: false
reversible: false

860188
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000138

860176
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000134

860164
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000132

metaid_0000087
type: Parameter
constant: true
value: 0.0038

metaid_0000147
type: Reaction
kinetic law: 860392
product: 860380
reactant: 860368
reactant: 860356
fast: false
reversible: false

860380
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000134

860368
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000133

860356
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000100

metaid_0000100
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 3.33333333333333E-4
in compartment: metaid_0000099
name: FTAz

metaid_0000019
type: Parameter
constant: true
value: 0.0025

metaid_0000066
type: Parameter
constant: true
value: 4.8E-4

metaid_0000035
type: Parameter
constant: true
value: 1.0E-4

metaid_0000173
type: Reaction
kinetic law: 861520
product: 861508
reactant: 861496
reactant: 861484
fast: false
reversible: false

861508
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000127

861496
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000129

861484
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000108

metaid_0000080
type: Parameter
constant: true
value: 4.8E-4

metaid_0000014
type: Parameter
constant: true
value: 2.0E-5

metaid_0000042
type: Parameter
constant: true
value: 5.0E-4

metaid_0000152
type: Reaction
kinetic law: 860668
modifier: 860656
modifier: 860644
product: 860632
reactant: 860620
fast: false
reversible: false

860632
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000104

860620
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000141

metaid_0000141
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000099
name: p150

metaid_0000061
type: Parameter
constant: true
value: 0.003

metaid_0000096
type: Parameter
constant: true
value: 0.003
name: =kr66/kf66

metaid_0000156
type: Reaction
kinetic law: 860812
product: 860800
reactant: 860788
fast: false
reversible: false

860800
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000125

860788
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000126

metaid_0000028
type: Parameter
constant: true
value: 0.001

metaid_0000021
type: Parameter
constant: true
value: 0.5

metaid_0000047
type: Parameter
constant: true
value: 0.0041

metaid_0000166
type: Reaction
kinetic law: 861208
product: 861196
reactant: 861184
reactant: 861172
fast: false
reversible: false

861196
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000128

861184
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000127

861172
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000116

metaid_0000075
type: Parameter
constant: true
value: 0.0038

metaid_0000182
type: Reaction
kinetic law: 861868
product: 861856
reactant: 861844
fast: false
reversible: false

861856
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000123

861844
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000127

metaid_0000180
type: Reaction
kinetic law: 861796
product: 861784
reactant: 861772
fast: false
reversible: false

861784
type: SpeciesReference
stoichiometry: 5.0
species: metaid_0000101

861772
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000108

metaid_0000007
type: Parameter
constant: true
value: 0.0015

metaid_0000054
type: Parameter
constant: true
value: 0.016

metaid_0000089
type: Parameter
constant: true
value: 2.0E-4

metaid_0000149
type: Reaction
kinetic law: 860488
product: 860476
product: 860464
reactant: 860452
fast: false
reversible: false

860476
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000131

860464
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000133

860452
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000137

metaid_0000023
type: Parameter
constant: true
value: 3.0E-4

metaid_0000068
type: Parameter
constant: true
value: 4.8E-4

metaid_0000161
type: Reaction
kinetic law: 861016
product: 861004
reactant: 860992
fast: false
reversible: false

861004
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000116

860992
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000117

metaid_0000037
type: Parameter
constant: true
value: 0.1

metaid_0000030
type: Parameter
constant: true
value: 0.0

metaid_0000175
type: Reaction
kinetic law: 861604
product: 861592
reactant: 861580
fast: false
reversible: false

861592
type: SpeciesReference
stoichiometry: 5.0
species: metaid_0000132

861580
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000129

metaid_0000084
type: Parameter
constant: true
value: 0.055

metaid_0000082
type: Parameter
constant: true
value: 0.055

metaid_0000144
type: Reaction
kinetic law: 860248
product: 860236
reactant: 860224
reactant: 860212
fast: false
reversible: false

860236
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000137

860224
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000136

860212
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000101

metaid_0000016
type: Parameter
constant: true
value: 0.0

metaid_0000170
type: Reaction
kinetic law: 861388
product: 861376
reactant: 861364
reactant: 861352
fast: false
reversible: false

861376
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000129

861364
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000105

861352
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000104

metaid_0000044
type: Parameter
constant: true
value: 0.06

metaid_0000154
type: Reaction
kinetic law: 860740
product: 860728
reactant: 860716
fast: false
reversible: false

860728
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000105

860716
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000140

metaid_0000063
type: Parameter
constant: true
value: 2.0E-4

metaid_0000158
type: Reaction
kinetic law: 860884
product: 860872
reactant: 860860
fast: false
reversible: false

860872
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000107

metaid_0000107
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000098
name: sa13_degraded

860860
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000108

metaid_0000049
type: Parameter
constant: true
value: 6.0E-5

metaid_0000077
type: Parameter
constant: true
value: 0.62

metaid_0000009
type: Parameter
constant: true
value: 0.24

metaid_0000011
type: Parameter
constant: true
value: 1.2

metaid_0000056
type: Parameter
constant: true
value: 5.0E-5

metaid_0000091
type: Parameter
constant: true
value: 6.66E-6
name: concentration of promoters

metaid_0000025
type: Parameter
constant: true
value: 0.0

metaid_0000163
type: Reaction
kinetic law: 861088
product: 861076
reactant: 861064
fast: false
reversible: false

861076
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000115

861064
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000117

metaid_0000072
type: Parameter
constant: true
value: 0.055