MODEL1303010000
type: SBMLModel
parameter: metaid bind L R to LR kr
parameter: metaid bind Apop XIAP kr
area units: area
parameter: metaid bind C3A C6pro to C3AC6pro kf
species: metaid s17
reaction: metaid r47
species: metaid s60
parameter: metaid bind BidM Bcl2 kr
parameter: metaid bind BidM Mcl1M kr
species: metaid s40
species: metaid s1
reaction: metaid r37
parameter: metaid bind BidM Mcl1M kf
volume units: volume
species: metaid s13
reaction: metaid r26
species: metaid s8
parameter: metaid catalyze XIAPC3A to XIAP C3ub kc
reaction: metaid r41
parameter: metaid bind Apop C3pro to ApopC3pro kr
reaction: metaid r34
parameter: metaid assemble pore sequential Bak 3 kr
parameter: metaid assemble pore sequential Bak 2 kf
parameter: metaid bind BAR C8A kf
parameter: metaid equilibrate SmacC to SmacA kf
parameter: metaid assemble pore sequential Bax 2 kr
parameter: metaid catalyze BidMBakM to BidM BakA kc
reaction: metaid r19
species: metaid s38
parameter: metaid catalyze C8ABidU to C8A BidT kc
species: metaid s53
species: metaid s12
parameter: metaid bind BidM BclxLM kf
parameter: metaid bind C8A BidU to C8ABidU kf
parameter: metaid bind XIAP C3A to XIAPC3A kr
reaction: metaid r42
parameter: metaid equilibrate BclxLC to BclxLM kr
species: metaid s57
species: metaid s19
reaction: metaid r49
species: metaid s62
species: metaid s11
species: metaid s52
parameter: metaid equilibrate CytoCC to CytoCA kr
species: metaid s3
parameter: metaid bind BidM BakM to BidMBakM kr
parameter: metaid bind BakA BclxLM kf
parameter: metaid bind BakA Mcl1 kr
parameter: metaid assemble pore sequential Bax 2 kf
species: metaid s15
reaction: metaid r57
parameter: metaid catalyze CytoCAApafI to CytoCA ApafA kc
species: metaid s56
parameter: metaid catalyze ApopC3pro to Apop C3A kc
species: metaid s49
species: metaid s10
reaction: metaid r21
reaction: metaid r0
species: metaid s41
parameter: metaid bind NoxaM Mcl1M kf
parameter: metaid bind BaxA BclxLM kr
species: metaid s2
reaction: metaid r14
reaction: metaid r24
species: metaid s55
reaction: metaid r54
species: metaid s14
species: metaid s45
parameter: metaid bind BidM BaxM to BidMBaxM kf
reaction: metaid r44
reaction: metaid r15
parameter: metaid bind BidM BakM to BidMBakM kf
parameter: metaid bind BaxA BaxM to BaxABaxM kf
parameter: metaid pore transport complex BakA 4 CytoCM kf
species: metaid s59
parameter: metaid pore transport dissociate BaxA 4 CytoCC kc
parameter: metaid bind BakA Mcl1 kf
parameter: metaid bind BadM Bcl2 kr
reaction: metaid r8

metaid bind L R to LR kr
type: Parameter
constant: true
value: 0.001
name: bind_L_R_to_LR_kr

metaid bind Apop XIAP kr
type: Parameter
constant: true
value: 0.001
name: bind_Apop_XIAP_kr

metaid bind C3A C6pro to C3AC6pro kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_C3A_C6pro_to_C3AC6pro_kf

metaid s17
type: Species
is: Q07820
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 20000.0
name: Mcl1(bf=None, state=M)

http://identifiers.org/biomodels.db/MODEL1303010000#_8d12c3ef_447a_40c6_9861_43b30607d410
type: Compartment
constant: true
size: 1.0
spatial dimensions: 3.0
name: default

metaid r47
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r47

metaid s72
type: Species
has only substance units: false
has part: P42574
name: Apop(bf=1) ._br_C3(bf=1, state=pro)
initial amount: 0.0
has part: GO:0043293
boundary condition: false
initial concentration: NaN
constant: false

metaid s62
type: Species
name: Bak(bf=1, s1=2, s2=3, state=A) ._br_Bak(bf=None, s1=3, s2=4, state=A) ._br_Bak(bf=None, s1=4, s2=5, state=A) ._br_Bak(bf=None, s1=5, s2=2, state=A) ._br_CytoC(bf=1, state=M)
initial concentration: NaN
constant: false
has part: Q16611
has only substance units: false
initial amount: 0.0
boundary condition: false
has part: P99999

metaid s64
type: Species
is: P99999
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: CytoC(bf=None, state=C)

metaid s30
type: Species
initial amount: 0.0
initial concentration: NaN
boundary condition: false
name: C3(bf=1, state=pro) ._br_C8(bf=1, state=A)
constant: false
has part: Q14790
has only substance units: false
has part: P42574

metaid s20
type: Species
is: Q9NR28
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 100000.0
name: Smac(bf=None, state=M)

metaid s51
type: Species
has part: Q07817
boundary condition: false
constant: false
has part: Q07812
initial amount: 0.0
has only substance units: false
initial concentration: NaN
name: Bax(bf=1, s1=None, s2=None, state=A) ._br_BclxL(bf=1, state=M)

metaid s69
type: Species
has part: Q9NR28
constant: false
has part: P98170
has only substance units: false
name: Smac(bf=1, state=A) ._br_XIAP(bf=1)
initial concentration: NaN
initial amount: 0.0
boundary condition: false

metaid s53
type: Species
has only substance units: false
name: Bak(bf=1, s1=None, s2=None, state=A) ._br_Mcl1(bf=1, state=M)
initial amount: 0.0
has part: Q16611
has part: Q07820
constant: false
boundary condition: false
initial concentration: NaN

metaid s35
type: Species
boundary condition: false
name: C3(bf=1, state=A) ._br_C6(bf=1, state=pro)
has part: P55212
has only substance units: false
has part: P42574
initial concentration: NaN
constant: false
initial amount: 0.0

metaid s43
type: Species
initial concentration: NaN
has only substance units: false
has part: Q07817
boundary condition: false
initial amount: 0.0
name: BclxL(bf=1, state=M) ._br_Bid(bf=1, state=M)
constant: false
has part: P55957

metaid s33
type: Species
initial amount: 0.0
has part: P98170
boundary condition: false
initial concentration: NaN
constant: false
name: C3(bf=1, state=A) ._br_XIAP(bf=1)
has part: P42574
has only substance units: false

metaid s0
type: Species
is: P50591
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 3000.0
name: L(bf=None)

metaid s45
type: Species
has part: Q14790
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
name: C6(bf=1, state=A) ._br_C8(bf=1, state=pro)
has part: P55212
initial amount: 0.0

metaid s2
type: Species
is: O15519
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 100.0
name: flip(bf=None)

metaid s25
type: Species
name: C8(bf=1, state=pro) ._br_DISC(bf=1)
boundary condition: false
has part: GO:0031264
constant: false
initial amount: 0.0
has part: Q14790
has only substance units: false
initial concentration: NaN

metaid s27
type: Species
is: Q14790
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: C8(bf=None, state=A)

metaid s70
type: Species
is: O14727
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Apaf(bf=None, state=A)

metaid s14
type: Species
is: Q16611
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 20000.0
name: Bak(bf=None, s1=None, s2=None, state=M)

metaid s16
type: Species
is: Q07817
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 20000.0
name: BclxL(bf=None, state=C)

metaid s58
type: Species
has part: Q07812
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Bax(bf=None, s1=1, s2=2, state=A) ._br_Bax(bf=None, s1=2, s2=3, state=A) ._br_Bax(bf=None, s1=3, s2=4, state=A) ._br_Bax(bf=None, s1=4, s2=1, state=A)

metaid s48
type: Species
has part: Q07812
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Bax(bf=1, s1=None, s2=None, state=A) ._br_Bax(bf=1, s1=None, s2=None, state=M)

metaid s7
type: Species
is: P55212
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 10000.0
name: C6(bf=None, state=pro)

metaid s9
type: Species
is: P09874
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 1000000.0
name: PARP(bf=None, state=U)

metaid s19
type: Species
is: P99999
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 500000.0
name: CytoC(bf=None, state=M)

metaid s71
type: Species
is: GO:0043293
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Apop(bf=None)

metaid s61
type: Species
has part: Q9NR28
boundary condition: false
constant: false
has part: Q07812
name: Bax(bf=1, s1=2, s2=3, state=A) ._br_Bax(bf=None, s1=3, s2=4, state=A) ._br_Bax(bf=None, s1=4, s2=5, state=A) ._br_Bax(bf=None, s1=5, s2=2, state=A) ._br_Smac(bf=1, state=M)
has only substance units: false
initial concentration: NaN
initial amount: 0.0

metaid s63
type: Species
initial concentration: NaN
boundary condition: false
has only substance units: false
initial amount: 0.0
has part: Q9NR28
name: Bak(bf=1, s1=2, s2=3, state=A) ._br_Bak(bf=None, s1=3, s2=4, state=A) ._br_Bak(bf=None, s1=4, s2=5, state=A) ._br_Bak(bf=None, s1=5, s2=2, state=A) ._br_Smac(bf=1, state=M)
has part: Q16611
constant: false

metaid s50
type: Species
initial amount: 0.0
has part: P10415
name: Bax(bf=1, s1=None, s2=None, state=A) ._br_Bcl2(bf=1)
initial concentration: NaN
constant: false
has part: Q07812
boundary condition: false
has only substance units: false

metaid s40
type: Species
has part: Q07812
initial concentration: NaN
boundary condition: false
initial amount: 0.0
has only substance units: false
has part: P55957
name: Bax(bf=1, s1=None, s2=None, state=M) ._br_Bid(bf=1, state=M)
constant: false

metaid s66
type: Species
is: Q9NR28
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Smac(bf=None, state=A)

metaid s52
type: Species
has part: Q07817
name: Bak(bf=1, s1=None, s2=None, state=A) ._br_BclxL(bf=1, state=M)
has only substance units: false
boundary condition: false
initial amount: 0.0
has part: Q16611
initial concentration: NaN
constant: false

metaid s42
type: Species
has only substance units: false
initial amount: 0.0
has part: P10415
constant: false
initial concentration: NaN
has part: P55957
name: Bcl2(bf=1) ._br_Bid(bf=1, state=M)
boundary condition: false

metaid s32
type: Species
is: P42574
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: C3(bf=None, state=A)

metaid s22
type: Species
is: Q07812
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Bax(bf=None, s1=None, s2=None, state=M)

metaid s68
type: Species
has part: P99999
constant: false
initial amount: 0.0
initial concentration: NaN
has part: O14727
name: Apaf(bf=1, state=I) ._br_CytoC(bf=1, state=A)
boundary condition: false
has only substance units: false

metaid s1
type: Species
is: O14763
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 200.0
name: R(bf=None)

metaid s34
type: Species
constant: false
initial amount: 0.0
has part: P09874
initial concentration: NaN
has part: P42574
boundary condition: false
name: C3(bf=1, state=A) ._br_PARP(bf=1, state=U)
has only substance units: false

metaid s24
type: Species
is: GO:0031264
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: DISC(bf=None)

metaid s11
type: Species
is: P55957
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 40000.0
name: Bid(bf=None, state=U)

metaid s13
type: Species
is: Q07812
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 80000.0
name: Bax(bf=None, s1=None, s2=None, state=C)

metaid s55
type: Species
has part: Q16611
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Bak(bf=None, s1=1, s2=None, state=A) ._br_Bak(bf=None, s1=None, s2=1, state=A)

metaid s57
type: Species
has part: Q16611
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Bak(bf=None, s1=1, s2=2, state=A) ._br_Bak(bf=None, s1=2, s2=3, state=A) ._br_Bak(bf=None, s1=3, s2=1, state=A)

metaid s47
type: Species
is: Q16611
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Bak(bf=None, s1=None, s2=None, state=A)

metaid s4
type: Species
is: Q9NZS9
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 1000.0
name: BAR(bf=None)

metaid s49
type: Species
has part: Q16611
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Bak(bf=1, s1=None, s2=None, state=A) ._br_Bak(bf=1, s1=None, s2=None, state=M)

metaid s29
type: Species
has only substance units: false
initial concentration: NaN
boundary condition: false
has part: Q9NZS9
has part: Q14790
constant: false
name: BAR(bf=1) ._br_C8(bf=1, state=A)
initial amount: 0.0

metaid s39
type: Species
is: P55212
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: C6(bf=None, state=A)

metaid s6
type: Species
is: P42574
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 10000.0
name: C3(bf=None, state=pro)

metaid s60
type: Species
initial concentration: NaN
has part: Q07812
has only substance units: false
constant: false
boundary condition: false
initial amount: 0.0
name: Bax(bf=1, s1=2, s2=3, state=A) ._br_Bax(bf=None, s1=3, s2=4, state=A) ._br_Bax(bf=None, s1=4, s2=5, state=A) ._br_Bax(bf=None, s1=5, s2=2, state=A) ._br_CytoC(bf=1, state=M)
has part: P99999

metaid s73
type: Species
has part: P98170
name: Apop(bf=1) ._br_XIAP(bf=1)
boundary condition: false
has part: GO:0043293
constant: false
initial concentration: NaN
has only substance units: false
initial amount: 0.0

metaid s65
type: Species
is: Q9NR28
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Smac(bf=None, state=C)

metaid s41
type: Species
name: Bak(bf=1, s1=None, s2=None, state=M) ._br_Bid(bf=1, state=M)
initial concentration: NaN
has only substance units: false
initial amount: 0.0
has part: Q16611
constant: false
has part: P55957
boundary condition: false

metaid s31
type: Species
is: P55957
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Bid(bf=None, state=T)

metaid s21
type: Species
has part: O14763
has part: P50591
boundary condition: false
name: L(bf=1) ._br_R(bf=1)
constant: false
initial concentration: NaN
has only substance units: false
initial amount: 0.0

metaid s67
type: Species
is: P99999
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: CytoC(bf=None, state=A)

metaid s23
type: Species
is: Q07817
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: BclxL(bf=None, state=M)

metaid s10
type: Species
is: P98170
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 100000.0
name: XIAP(bf=None)

metaid s54
type: Species
has part: Q07812
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Bax(bf=None, s1=1, s2=None, state=A) ._br_Bax(bf=None, s1=None, s2=1, state=A)

metaid s44
type: Species
has part: Q07820
has only substance units: false
initial amount: 0.0
name: Bid(bf=1, state=M) ._br_Mcl1(bf=1, state=M)
initial concentration: NaN
constant: false
has part: P55957
boundary condition: false

metaid s56
type: Species
has part: Q07812
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Bax(bf=None, s1=1, s2=2, state=A) ._br_Bax(bf=None, s1=2, s2=3, state=A) ._br_Bax(bf=None, s1=3, s2=1, state=A)

metaid s36
type: Species
is: P55957
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Bid(bf=None, state=M)

metaid s46
type: Species
is: Q07812
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Bax(bf=None, s1=None, s2=None, state=A)

metaid s3
type: Species
is: Q14790
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 20000.0
name: C8(bf=None, state=pro)

metaid s26
type: Species
initial concentration: NaN
constant: false
boundary condition: false
initial amount: 0.0
has only substance units: false
has part: O15519
has part: GO:0031264
name: DISC(bf=1) ._br_flip(bf=1)

metaid s5
type: Species
is: O14727
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 100000.0
name: Apaf(bf=None, state=I)

metaid s28
type: Species
initial concentration: NaN
has part: Q14790
boundary condition: false
name: Bid(bf=1, state=U) ._br_C8(bf=1, state=A)
constant: false
has only substance units: false
initial amount: 0.0
has part: P55957

metaid s15
type: Species
is: P10415
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 20000.0
name: Bcl2(bf=None)

metaid s59
type: Species
has part: Q16611
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: Bak(bf=None, s1=1, s2=2, state=A) ._br_Bak(bf=None, s1=2, s2=3, state=A) ._br_Bak(bf=None, s1=3, s2=4, state=A) ._br_Bak(bf=None, s1=4, s2=1, state=A)

metaid s8
type: Species
is: P55211
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 100000.0
name: C9(bf=None)

http://identifiers.org/biomodels.db/MODEL1303010000#_47a461d9_aeed_4ecc_8b09_9462168d0932
type: SpeciesReference
stoichiometry: 1.0
species: metaid s65

http://identifiers.org/biomodels.db/MODEL1303010000#_02ce05d6_cbb2_46ed_aedb_0db5c6062a16
type: SpeciesReference
stoichiometry: 1.0
species: metaid s58

http://identifiers.org/biomodels.db/MODEL1303010000#_4648f17f_fc60_411b_bbd3_72b47ebee39c
type: SpeciesReference
stoichiometry: 1.0
species: metaid s61

metaid bind BidM Bcl2 kr
type: Parameter
constant: true
value: 0.066
name: bind_BidM_Bcl2_kr

metaid bind BidM Mcl1M kr
type: Parameter
constant: true
value: 0.01
name: bind_BidM_Mcl1M_kr

metaid r37
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r37

http://identifiers.org/biomodels.db/MODEL1303010000#_5ff3ca88_1944_4df4_846c_f0b5f0be9afb
type: SpeciesReference
stoichiometry: 1.0
species: metaid s47

http://identifiers.org/biomodels.db/MODEL1303010000#ff055685_2ff1_4b53_a1c0_d1d087e8755b
type: SpeciesReference
stoichiometry: 1.0
species: metaid s47

http://identifiers.org/biomodels.db/MODEL1303010000#f92c6a5c_3436_482d_9b38_0228fac97884
type: SpeciesReference
stoichiometry: 1.0
species: metaid s49

metaid bind BidM Mcl1M kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_BidM_Mcl1M_kf

metaid r26
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r26

http://identifiers.org/biomodels.db/MODEL1303010000#_4685047c_a399_4c60_90a9_c1afddb25a11
type: SpeciesReference
stoichiometry: 1.0
species: metaid s47

http://identifiers.org/biomodels.db/MODEL1303010000#_54862fcc_5113_49b5_9f9c_d894a2cfaacb
type: SpeciesReference
stoichiometry: 1.0
species: metaid s36

http://identifiers.org/biomodels.db/MODEL1303010000#_9270211f_7fe1_437c_9a6a_3070a54e6515
type: SpeciesReference
stoichiometry: 1.0
species: metaid s41

metaid catalyze XIAPC3A to XIAP C3ub kc
type: Parameter
constant: true
value: 0.1
name: catalyze_XIAPC3A_to_XIAP_C3ub_kc

metaid r41
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r41

http://identifiers.org/biomodels.db/MODEL1303010000#d17cc54f_42b4_4669_bded_584a4c0aba5d
type: SpeciesReference
stoichiometry: 1.0
species: metaid s59

http://identifiers.org/biomodels.db/MODEL1303010000#c4cf188f_3e0a_41e9_a2f3_8d7b8133744e
type: SpeciesReference
stoichiometry: 1.0
species: metaid s57

http://identifiers.org/biomodels.db/MODEL1303010000#_3399108c_216e_4b86_acaf_41c5b00d8935
type: SpeciesReference
stoichiometry: 1.0
species: metaid s47

metaid bind Apop C3pro to ApopC3pro kr
type: Parameter
constant: true
value: 0.001
name: bind_Apop_C3pro_to_ApopC3pro_kr

metaid r34
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r34

http://identifiers.org/biomodels.db/MODEL1303010000#_0599febb_5749_4047_ac32_495be70e86a1
type: SpeciesReference
stoichiometry: 1.0
species: metaid s54

http://identifiers.org/biomodels.db/MODEL1303010000#_3a0764e5_f055_4592_8852_d6e2b07fd2de
type: SpeciesReference
stoichiometry: 1.0
species: metaid s46

http://identifiers.org/biomodels.db/MODEL1303010000#e14948fd_8d4f_451e_8b7c_3fcc6e89d429
type: SpeciesReference
stoichiometry: 1.0
species: metaid s46

metaid assemble pore sequential Bak 3 kr
type: Parameter
constant: true
value: 0.001
name: assemble_pore_sequential_Bak_3_kr

metaid assemble pore sequential Bak 2 kf
type: Parameter
constant: true
value: 2.040816E-4
name: assemble_pore_sequential_Bak_2_kf

metaid bind BAR C8A kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_BAR_C8A_kf

metaid equilibrate SmacC to SmacA kf
type: Parameter
constant: true
value: 0.01
name: equilibrate_SmacC_to_SmacA_kf

metaid assemble pore sequential Bax 2 kr
type: Parameter
constant: true
value: 0.001
name: assemble_pore_sequential_Bax_2_kr

metaid catalyze BidMBakM to BidM BakA kc
type: Parameter
constant: true
value: 1.0
name: catalyze_BidMBakM_to_BidM_BakA_kc

metaid r19
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r19

http://identifiers.org/biomodels.db/MODEL1303010000#e9ed704f_82fa_4fd0_9b19_5df84877da4b
type: SpeciesReference
stoichiometry: 1.0
species: metaid s40

http://identifiers.org/biomodels.db/MODEL1303010000#ad525083_9ed4_43b7_b204_8db0b250e726
type: SpeciesReference
stoichiometry: 1.0
species: metaid s36

http://identifiers.org/biomodels.db/MODEL1303010000#b5e9b0bc_7b1d_4bb5_a6e2_13dbfc3b5b01
type: SpeciesReference
stoichiometry: 1.0
species: metaid s22

metaid s38
type: Species
is: P09874
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: PARP(bf=None, state=C)

metaid catalyze C8ABidU to C8A BidT kc
type: Parameter
constant: true
value: 1.0
name: catalyze_C8ABidU_to_C8A_BidT_kc

metaid s12
type: Species
is: Q92934
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 1000.0
name: Bad(bf=None, state=C)

metaid bind BidM BclxLM kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_BidM_BclxLM_kf

metaid bind C8A BidU to C8ABidU kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_C8A_BidU_to_C8ABidU_kf

metaid bind XIAP C3A to XIAPC3A kr
type: Parameter
constant: true
value: 0.001
name: bind_XIAP_C3A_to_XIAPC3A_kr

metaid r42
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r42

http://identifiers.org/biomodels.db/MODEL1303010000#_0affd5fb_15dd_4805_9f03_b732f615c939
type: SpeciesReference
stoichiometry: 1.0
species: metaid s60

http://identifiers.org/biomodels.db/MODEL1303010000#_50d72139_1501_4f5e_843a_163d534e724b
type: SpeciesReference
stoichiometry: 1.0
species: metaid s58

http://identifiers.org/biomodels.db/MODEL1303010000#_1c9b2bc7_653b_4916_8427_71f4b418dc72
type: SpeciesReference
stoichiometry: 1.0
species: metaid s19

metaid equilibrate BclxLC to BclxLM kr
type: Parameter
constant: true
value: 0.01
name: equilibrate_BclxLC_to_BclxLM_kr

metaid r49
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r49

http://identifiers.org/biomodels.db/MODEL1303010000#_836048cc_5919_49c3_b0fb_4fa689bb9fda
type: SpeciesReference
stoichiometry: 1.0
species: metaid s65

http://identifiers.org/biomodels.db/MODEL1303010000#cce56b77_bad0_4ddd_8da9_57ee889d98da
type: SpeciesReference
stoichiometry: 1.0
species: metaid s59

http://identifiers.org/biomodels.db/MODEL1303010000#_9a884458_bd08_4571_8792_fbe47e281c68
type: SpeciesReference
stoichiometry: 1.0
species: metaid s63

metaid equilibrate CytoCC to CytoCA kr
type: Parameter
constant: true
value: 0.01
name: equilibrate_CytoCC_to_CytoCA_kr

metaid bind BidM BakM to BidMBakM kr
type: Parameter
constant: true
value: 0.001
name: bind_BidM_BakM_to_BidMBakM_kr

metaid bind BakA BclxLM kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_BakA_BclxLM_kf

metaid bind BakA Mcl1 kr
type: Parameter
constant: true
value: 0.01
name: bind_BakA_Mcl1_kr

metaid assemble pore sequential Bax 2 kf
type: Parameter
constant: true
value: 2.040816E-4
name: assemble_pore_sequential_Bax_2_kf

metaid r57
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r57

http://identifiers.org/biomodels.db/MODEL1303010000#_846e91cd_d067_4ef4_a206_647987f7bd4d
type: SpeciesReference
stoichiometry: 1.0
species: metaid s73

http://identifiers.org/biomodels.db/MODEL1303010000#_345c26ac_b581_4cfe_a3d6_19b0be27fa69
type: SpeciesReference
stoichiometry: 1.0
species: metaid s71

http://identifiers.org/biomodels.db/MODEL1303010000#c197612f_5f47_42e0_a272_363264d307d1
type: SpeciesReference
stoichiometry: 1.0
species: metaid s10

metaid catalyze CytoCAApafI to CytoCA ApafA kc
type: Parameter
constant: true
value: 1.0
name: catalyze_CytoCAApafI_to_CytoCA_ApafA_kc

metaid catalyze ApopC3pro to Apop C3A kc
type: Parameter
constant: true
value: 1.0
name: catalyze_ApopC3pro_to_Apop_C3A_kc

metaid r21
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r21

http://identifiers.org/biomodels.db/MODEL1303010000#_65c151ef_b5dd_4741_aad6_f44980cc58c1
type: SpeciesReference
stoichiometry: 1.0
species: metaid s42

http://identifiers.org/biomodels.db/MODEL1303010000#_75c37f77_9b30_432a_8049_e0c78863dfab
type: SpeciesReference
stoichiometry: 1.0
species: metaid s36

http://identifiers.org/biomodels.db/MODEL1303010000#caefc476_21cd_4f4b_a97a_357f2e7d16e3
type: SpeciesReference
stoichiometry: 1.0
species: metaid s15

metaid r0
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r0

http://identifiers.org/biomodels.db/MODEL1303010000#_4e333a9b_7f4d_4fe4_a767_592fac64c4e4
type: SpeciesReference
stoichiometry: 1.0
species: metaid s21

http://identifiers.org/biomodels.db/MODEL1303010000#f6e05c0b_bbd9_4abf_8cbb_20fb60942375
type: SpeciesReference
stoichiometry: 1.0
species: metaid s1

http://identifiers.org/biomodels.db/MODEL1303010000#aebb81a3_71a4_4505_810c_40451218a391
type: SpeciesReference
stoichiometry: 1.0
species: metaid s0

metaid bind NoxaM Mcl1M kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_NoxaM_Mcl1M_kf

metaid bind BaxA BclxLM kr
type: Parameter
constant: true
value: 0.01
name: bind_BaxA_BclxLM_kr

metaid r14
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r14

http://identifiers.org/biomodels.db/MODEL1303010000#_4a5727e2_1245_4a36_bab9_7416096dc52c
type: SpeciesReference
stoichiometry: 1.0
species: metaid s35

http://identifiers.org/biomodels.db/MODEL1303010000#b5677450_3b82_419e_bcf1_95576bc3c8c5
type: SpeciesReference
stoichiometry: 1.0
species: metaid s32

http://identifiers.org/biomodels.db/MODEL1303010000#f898272f_d238_4b19_9d72_fa369f19197f
type: SpeciesReference
stoichiometry: 1.0
species: metaid s7

metaid r24
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r24

http://identifiers.org/biomodels.db/MODEL1303010000#_61a0578e_dbb6_4f84_bec3_ebc799ec837e
type: SpeciesReference
stoichiometry: 1.0
species: metaid s45

http://identifiers.org/biomodels.db/MODEL1303010000#_1f645607_0222_417c_a569_5b987d373665
type: SpeciesReference
stoichiometry: 1.0
species: metaid s39

http://identifiers.org/biomodels.db/MODEL1303010000#_2f292bdf_03ca_4645_8bab_3798f212eaab
type: SpeciesReference
stoichiometry: 1.0
species: metaid s3

metaid r54
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r54

http://identifiers.org/biomodels.db/MODEL1303010000#_9d697ef8_c5b1_4a3b_8ec7_3d67e93f2b23
type: SpeciesReference
stoichiometry: 1.0
species: metaid s70

http://identifiers.org/biomodels.db/MODEL1303010000#_0846201d_84f6_45e2_bc01_4fd34ee0b900
type: SpeciesReference
stoichiometry: 1.0
species: metaid s67

http://identifiers.org/biomodels.db/MODEL1303010000#ecb91903_0598_4fb5_921c_a21c658854dc
type: SpeciesReference
stoichiometry: 1.0
species: metaid s68

metaid bind BidM BaxM to BidMBaxM kf
type: Parameter
constant: true
value: 1.0E-7
name: bind_BidM_BaxM_to_BidMBaxM_kf

metaid r44
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r44

http://identifiers.org/biomodels.db/MODEL1303010000#_78bd5846_f5c8_46d1_b940_e95318488175
type: SpeciesReference
stoichiometry: 1.0
species: metaid s62

http://identifiers.org/biomodels.db/MODEL1303010000#_7d898114_2d37_40b1_8060_4959236f5c7c
type: SpeciesReference
stoichiometry: 1.0
species: metaid s59

http://identifiers.org/biomodels.db/MODEL1303010000#_612d77cd_50f0_4549_b34b_ce1896b32194
type: SpeciesReference
stoichiometry: 1.0
species: metaid s19

metaid r15
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r15

http://identifiers.org/biomodels.db/MODEL1303010000#ea281f3c_6505_471f_9699_7ad536f5e720
type: SpeciesReference
stoichiometry: 1.0
species: metaid s36

http://identifiers.org/biomodels.db/MODEL1303010000#_82f3b88c_6c24_402f_9300_6ac60808e1ef
type: SpeciesReference
stoichiometry: 1.0
species: metaid s31

metaid bind BidM BakM to BidMBakM kf
type: Parameter
constant: true
value: 1.0E-7
name: bind_BidM_BakM_to_BidMBakM_kf

metaid bind BaxA BaxM to BaxABaxM kf
type: Parameter
constant: true
value: 1.0E-7
name: bind_BaxA_BaxM_to_BaxABaxM_kf

metaid pore transport complex BakA 4 CytoCM kf
type: Parameter
constant: true
value: 2.857143E-5
name: pore_transport_complex_BakA_4_CytoCM_kf

metaid pore transport dissociate BaxA 4 CytoCC kc
type: Parameter
constant: true
value: 10.0
name: pore_transport_dissociate_BaxA_4_CytoCC_kc

metaid bind BakA Mcl1 kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_BakA_Mcl1_kf

metaid bind BadM Bcl2 kr
type: Parameter
constant: true
value: 0.010999999999999998
name: bind_BadM_Bcl2_kr

metaid r8
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r8

http://identifiers.org/biomodels.db/MODEL1303010000#_8f345531_91f0_4d62_a50c_51ab0cb3b3f4
type: SpeciesReference
stoichiometry: 1.0
species: metaid s29

http://identifiers.org/biomodels.db/MODEL1303010000#_723b4239_5b1d_46ba_931d_a605a0aab2f5
type: SpeciesReference
stoichiometry: 1.0
species: metaid s27

http://identifiers.org/biomodels.db/MODEL1303010000#_3369d7ab_3048_4f54_9052_86f43b6c2ccb
type: SpeciesReference
stoichiometry: 1.0
species: metaid s4

metaid r55
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r55

http://identifiers.org/biomodels.db/MODEL1303010000#_207ae45c_cbee_4c93_bfba_9539d1cf0ffe
type: SpeciesReference
stoichiometry: 1.0
species: metaid s71

http://identifiers.org/biomodels.db/MODEL1303010000#bdf85058_e1a5_4ddf_be71_38ff0cb075f1
type: SpeciesReference
stoichiometry: 1.0
species: metaid s70

http://identifiers.org/biomodels.db/MODEL1303010000#c2a0726e_ca90_4738_8255_1239ba6703a9
type: SpeciesReference
stoichiometry: 1.0
species: metaid s8

metaid bind C3A PARPU to C3APARPU kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_C3A_PARPU_to_C3APARPU_kf

metaid assemble pore sequential Bak 4 kr
type: Parameter
constant: true
value: 0.001
name: assemble_pore_sequential_Bak_4_kr

metaid r22
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r22

http://identifiers.org/biomodels.db/MODEL1303010000#_1bf3a7c3_361c_49c3_a8f2_8605fe51ca51
type: SpeciesReference
stoichiometry: 1.0
species: metaid s43

http://identifiers.org/biomodels.db/MODEL1303010000#c3097ffa_23ec_42c7_b838_b0dbb8e051ee
type: SpeciesReference
stoichiometry: 1.0
species: metaid s36

http://identifiers.org/biomodels.db/MODEL1303010000#eab8897e_be42_48c1_bb81_5ce9c0213b9f
type: SpeciesReference
stoichiometry: 1.0
species: metaid s23

metaid assemble pore sequential Bak 4 kf
type: Parameter
constant: true
value: 2.040816E-4
name: assemble_pore_sequential_Bak_4_kf

metaid r5
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r5

http://identifiers.org/biomodels.db/MODEL1303010000#_8d27cce9_85ac_404b_bbeb_964638072d7c
type: SpeciesReference
stoichiometry: 1.0
species: metaid s26

http://identifiers.org/biomodels.db/MODEL1303010000#e5b79e6b_70bd_4116_8e75_509bd363df9a
type: SpeciesReference
stoichiometry: 1.0
species: metaid s24

http://identifiers.org/biomodels.db/MODEL1303010000#_93971bab_ec3a_4913_a040_d7a552fbd552
type: SpeciesReference
stoichiometry: 1.0
species: metaid s2

metaid bind DISC flip kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_DISC_flip_kf

metaid bind C8A C3pro to C8AC3pro kr
type: Parameter
constant: true
value: 0.001
name: bind_C8A_C3pro_to_C8AC3pro_kr

metaid bind BakA BakM to BakABakM kf
type: Parameter
constant: true
value: 1.0E-7
name: bind_BakA_BakM_to_BakABakM_kf

metaid r31
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r31

http://identifiers.org/biomodels.db/MODEL1303010000#aa1114c4_30e0_4f12_8c68_13edf166c046
type: SpeciesReference
stoichiometry: 1.0
species: metaid s51

http://identifiers.org/biomodels.db/MODEL1303010000#_392738ed_47af_4355_b458_6d2e902125cb
type: SpeciesReference
stoichiometry: 1.0
species: metaid s46

http://identifiers.org/biomodels.db/MODEL1303010000#abc57752_4099_4adf_ab35_c6daabb8fe52
type: SpeciesReference
stoichiometry: 1.0
species: metaid s23

metaid r16
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r16

http://identifiers.org/biomodels.db/MODEL1303010000#_7af4b316_6d4b_4cc4_9a12_31ced2ae23d4
type: SpeciesReference
stoichiometry: 1.0
species: metaid s37

metaid s37
type: Species
is: P42574
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
name: C3(bf=None, state=ub)

http://identifiers.org/biomodels.db/MODEL1303010000#_1f037af4_1006_4125_ae4c_2308257cc1e4
type: SpeciesReference
stoichiometry: 1.0
species: metaid s10

http://identifiers.org/biomodels.db/MODEL1303010000#_8b37f646_de0c_4093_9fb1_a13ad917b585
type: SpeciesReference
stoichiometry: 1.0
species: metaid s33

metaid catalyze BidMBaxM to BidM BaxA kc
type: Parameter
constant: true
value: 1.0
name: catalyze_BidMBaxM_to_BidM_BaxA_kc

metaid r56
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r56

http://identifiers.org/biomodels.db/MODEL1303010000#_9d746c10_079d_40ca_95db_addc6bce8aae
type: SpeciesReference
stoichiometry: 1.0
species: metaid s72

http://identifiers.org/biomodels.db/MODEL1303010000#f5c88e1c_7f4e_4918_bf59_b20989f82238
type: SpeciesReference
stoichiometry: 1.0
species: metaid s71

http://identifiers.org/biomodels.db/MODEL1303010000#ebcb3388_b24a_4480_b004_edef02d75ba8
type: SpeciesReference
stoichiometry: 1.0
species: metaid s6

metaid r27
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r27

http://identifiers.org/biomodels.db/MODEL1303010000#aec9a228_0b4e_4df2_a743_c13fe9f2bb21
type: SpeciesReference
stoichiometry: 1.0
species: metaid s39

http://identifiers.org/biomodels.db/MODEL1303010000#_961d0600_6142_408c_ac05_c25137c7cec0
type: SpeciesReference
stoichiometry: 1.0
species: metaid s27

http://identifiers.org/biomodels.db/MODEL1303010000#_11a18803_ec15_46db_a16e_a0e57e30abf2
type: SpeciesReference
stoichiometry: 1.0
species: metaid s45

metaid r6
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r6

http://identifiers.org/biomodels.db/MODEL1303010000#_180bf77f_bc09_4e26_bdc5_cd26cc52b38f
type: SpeciesReference
stoichiometry: 1.0
species: metaid s27

http://identifiers.org/biomodels.db/MODEL1303010000#_7855b27e_9237_479f_ab8c_071965ab7f81
type: SpeciesReference
stoichiometry: 1.0
species: metaid s24

http://identifiers.org/biomodels.db/MODEL1303010000#_4f7eb2ad_aa2e_4984_a36f_74cf86112b4e
type: SpeciesReference
stoichiometry: 1.0
species: metaid s25

metaid equilibrate BaxC to BaxM kr
type: Parameter
constant: true
value: 0.01
name: equilibrate_BaxC_to_BaxM_kr

metaid bind BidM Bcl2 kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_BidM_Bcl2_kf

metaid bind C6A C8pro to C6AC8pro kr
type: Parameter
constant: true
value: 0.001
name: bind_C6A_C8pro_to_C6AC8pro_kr

metaid pore transport complex BakA 4 SmacM kr
type: Parameter
constant: true
value: 0.001
name: pore_transport_complex_BakA_4_SmacM_kr

metaid bind BidM BaxM to BidMBaxM kr
type: Parameter
constant: true
value: 0.001
name: bind_BidM_BaxM_to_BidMBaxM_kr

metaid bind BaxA BaxM to BaxABaxM kr
type: Parameter
constant: true
value: 0.001
name: bind_BaxA_BaxM_to_BaxABaxM_kr

metaid bind CytoCA ApafI to CytoCAApafI kr
type: Parameter
constant: true
value: 0.001
name: bind_CytoCA_ApafI_to_CytoCAApafI_kr

metaid convert ApafA C9 to Apop kf
type: Parameter
constant: true
value: 5.0E-8
name: convert_ApafA_C9_to_Apop_kf

metaid bind DISC C8pro to DISCC8pro kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_DISC_C8pro_to_DISCC8pro_kf

metaid catalyze BakABakM to BakA BakA kc
type: Parameter
constant: true
value: 1.0
name: catalyze_BakABakM_to_BakA_BakA_kc

metaid r32
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r32

http://identifiers.org/biomodels.db/MODEL1303010000#e6be56ec_6e9b_4f0f_a040_ea852e8b2661
type: SpeciesReference
stoichiometry: 1.0
species: metaid s52

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s47

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s23

metaid bind BaxA Bcl2 kr
type: Parameter
constant: true
value: 0.01
name: bind_BaxA_Bcl2_kr

metaid bind CytoCA ApafI to CytoCAApafI kf
type: Parameter
constant: true
value: 5.0E-7
name: bind_CytoCA_ApafI_to_CytoCAApafI_kf

metaid convert ApafA C9 to Apop kr
type: Parameter
constant: true
value: 0.001
name: convert_ApafA_C9_to_Apop_kr

metaid r13
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r13

http://identifiers.org/biomodels.db/MODEL1303010000#c6292661_4770_44fe_8fa1_165c9e76dc70
type: SpeciesReference
stoichiometry: 1.0
species: metaid s34

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s32

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s9

metaid bind BaxA Bcl2 kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_BaxA_Bcl2_kf

metaid r17
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r17

http://identifiers.org/biomodels.db/MODEL1303010000#aeb77f84_7c84_4449_bc3a_df8f5bcaa8c6
type: SpeciesReference
stoichiometry: 1.0
species: metaid s38

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s32

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s34

metaid bind Apop C3pro to ApopC3pro kf
type: Parameter
constant: true
value: 5.0E-9
name: bind_Apop_C3pro_to_ApopC3pro_kf

metaid r53
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r53

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s69

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s66

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s10

metaid assemble pore sequential Bax 3 kr
type: Parameter
constant: true
value: 0.001
name: assemble_pore_sequential_Bax_3_kr

metaid r43
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r43

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s61

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s58

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s20

metaid assemble pore sequential Bak 3 kf
type: Parameter
constant: true
value: 2.040816E-4
name: assemble_pore_sequential_Bak_3_kf

metaid r7
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r7

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s28

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s27

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s11

metaid r46
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r46

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s64

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s58

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s60

metaid r28
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r28

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s48

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s46

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s22

metaid convert LR to DISC kc
type: Parameter
constant: true
value: 1.0E-5
name: convert_LR_to_DISC_kc

metaid r33
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r33

http://identifiers.org/biomodels.db/MODEL1303010000#_69fb72f2_ecc6_4df0_950a_1516cf7fe751
type: SpeciesReference
stoichiometry: 1.0
species: metaid s53

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s47

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s17

metaid pore transport complex BaxA 4 CytoCM kr
type: Parameter
constant: true
value: 0.001
name: pore_transport_complex_BaxA_4_CytoCM_kr

metaid bind BakA BakM to BakABakM kr
type: Parameter
constant: true
value: 0.001
name: bind_BakA_BakM_to_BakABakM_kr

metaid bind XIAP C3A to XIAPC3A kf
type: Parameter
constant: true
value: 2.0E-6
name: bind_XIAP_C3A_to_XIAPC3A_kf

metaid r10
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r10

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s31

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s27

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s28

metaid assemble pore sequential Bak 2 kr
type: Parameter
constant: true
value: 0.001
name: assemble_pore_sequential_Bak_2_kr

metaid equilibrate BclxLC to BclxLM kf
type: Parameter
constant: true
value: 0.01
name: equilibrate_BclxLC_to_BclxLM_kf

metaid bind BAR C8A kr
type: Parameter
constant: true
value: 0.001
name: bind_BAR_C8A_kr

metaid equilibrate SmacC to SmacA kr
type: Parameter
constant: true
value: 0.01
name: equilibrate_SmacC_to_SmacA_kr

metaid r50
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r50

http://identifiers.org/biomodels.db/MODEL1303010000#e361d0ac_a0e2_4244_9022_a4af1605cfb8
type: SpeciesReference
stoichiometry: 1.0
species: metaid s66

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s65

metaid pore transport dissociate BakA 4 SmacC kc
type: Parameter
constant: true
value: 10.0
name: pore_transport_dissociate_BakA_4_SmacC_kc

metaid r40
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r40

http://identifiers.org/biomodels.db/MODEL1303010000#d085e6e9_0c9e_4233_b3e5_7cf4ec6617ca
type: SpeciesReference
stoichiometry: 1.0
species: metaid s58

http://identifiers.org/biomodels.db/MODEL1303010000#_76b8b2fd_1175_4529_8550_f912c648020e
type: SpeciesReference
stoichiometry: 1.0
species: metaid s56

http://identifiers.org/biomodels.db/MODEL1303010000#da1e3724_d2ab_4849_abcb_d64517dcc0d2
type: SpeciesReference
stoichiometry: 1.0
species: metaid s46

metaid bind BidM BclxLM kr
type: Parameter
constant: true
value: 0.012
name: bind_BidM_BclxLM_kr

metaid r30
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r30

http://identifiers.org/biomodels.db/MODEL1303010000#_7e6a139e_f2d8_4462_a97d_6a90cf9e1087
type: SpeciesReference
stoichiometry: 1.0
species: metaid s50

http://identifiers.org/biomodels.db/MODEL1303010000#c7491371_552d_4e68_b69d_26daab42ea71
type: SpeciesReference
stoichiometry: 1.0
species: metaid s46

http://identifiers.org/biomodels.db/MODEL1303010000#d7076d23_d841_44cf_8372_6e496a4cb046
type: SpeciesReference
stoichiometry: 1.0
species: metaid s15

metaid assemble pore sequential Bax 4 kr
type: Parameter
constant: true
value: 0.001
name: assemble_pore_sequential_Bax_4_kr

metaid bind C8A BidU to C8ABidU kr
type: Parameter
constant: true
value: 0.001
name: bind_C8A_BidU_to_C8ABidU_kr

metaid equilibrate CytoCC to CytoCA kf
type: Parameter
constant: true
value: 0.01
name: equilibrate_CytoCC_to_CytoCA_kf

metaid catalyze C8AC3pro to C8A C3A kc
type: Parameter
constant: true
value: 1.0
name: catalyze_C8AC3pro_to_C8A_C3A_kc

metaid r11
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r11

http://identifiers.org/biomodels.db/MODEL1303010000#bd64a0e8_e1eb_4f9b_9d34_95657d55fd44
type: SpeciesReference
stoichiometry: 1.0
species: metaid s32

http://identifiers.org/biomodels.db/MODEL1303010000#ec825887_7841_476b_8563_bad503270808
type: SpeciesReference
stoichiometry: 1.0
species: metaid s27

http://identifiers.org/biomodels.db/MODEL1303010000#_45ddac5b_383e_438d_a68c_a8344dc700f8
type: SpeciesReference
stoichiometry: 1.0
species: metaid s30

metaid r25
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r25

http://identifiers.org/biomodels.db/MODEL1303010000#_99557ff1_e59b_4580_8a4c_d9594e9795d3
type: SpeciesReference
stoichiometry: 1.0
species: metaid s46

http://identifiers.org/biomodels.db/MODEL1303010000#c10242d4_0bc0_4288_983f_eda5bb2e8b29
type: SpeciesReference
stoichiometry: 1.0
species: metaid s36

http://identifiers.org/biomodels.db/MODEL1303010000#_0e76351d_aaac_4c17_952c_6c210dd909e9
type: SpeciesReference
stoichiometry: 1.0
species: metaid s40

metaid bind SmacA XIAP kr
type: Parameter
constant: true
value: 0.001
name: bind_SmacA_XIAP_kr

metaid r4
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r4

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s25

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s24

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s3

metaid assemble pore sequential Bax 3 kf
type: Parameter
constant: true
value: 2.040816E-4
name: assemble_pore_sequential_Bax_3_kf

metaid r51
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r51

http://identifiers.org/biomodels.db/MODEL1303010000#_6f476515_6490_42cb_9b55_a344880108c1
type: SpeciesReference
stoichiometry: 1.0
species: metaid s67

http://identifiers.org/biomodels.db/MODEL1303010000#_2159d6c7_24d0_445f_9414_9261d2727dc7
type: SpeciesReference
stoichiometry: 1.0
species: metaid s64

metaid r29
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r29

http://identifiers.org/biomodels.db/MODEL1303010000#c41d1a65_afcd_45ea_800e_5c80e7d7ca7f
type: SpeciesReference
stoichiometry: 1.0
species: metaid s49

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s47

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s14

metaid catalyze DISCC8pro to DISC C8A kc
type: Parameter
constant: true
value: 1.0
name: catalyze_DISCC8pro_to_DISC_C8A_kc

metaid pore transport complex BaxA 4 CytoCM kf
type: Parameter
constant: true
value: 2.857143E-5
name: pore_transport_complex_BaxA_4_CytoCM_kf

metaid r58
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r58

http://identifiers.org/biomodels.db/MODEL1303010000#bd77f3da_af12_4aa6_a6e8_9829659586ac
type: SpeciesReference
stoichiometry: 1.0
species: metaid s71

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s32

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s72

metaid catalyze C6AC8pro to C6A C8A kc
type: Parameter
constant: true
value: 1.0
name: catalyze_C6AC8pro_to_C6A_C8A_kc

metaid r45
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r45

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s63

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s59

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s20

metaid bind BakA BclxLM kr
type: Parameter
constant: true
value: 0.049999999999999996
name: bind_BakA_BclxLM_kr

metaid bind DISC C8pro to DISCC8pro kr
type: Parameter
constant: true
value: 0.001
name: bind_DISC_C8pro_to_DISCC8pro_kr

metaid r1
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r1

http://identifiers.org/biomodels.db/MODEL1303010000#a6a912dd_f78b_429a_869d_d910c074077e
type: SpeciesReference
stoichiometry: 1.0
species: metaid s22

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s13

metaid pore transport dissociate BakA 4 CytoCC kc
type: Parameter
constant: true
value: 10.0
name: pore_transport_dissociate_BakA_4_CytoCC_kc

metaid r38
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r38

http://identifiers.org/biomodels.db/MODEL1303010000#_5bd4fbb7_644c_4b81_8904_68dd3f90b4a0
type: SpeciesReference
stoichiometry: 1.0
species: metaid s56

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s54

http://identifiers.org/biomodels.db/MODEL1303010000#_6129fba8_5679_4d78_9be4_ed6892200ded
type: SpeciesReference
stoichiometry: 1.0
species: metaid s46

metaid r48
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r48

http://identifiers.org/biomodels.db/MODEL1303010000#_7d59f3c8_ae16_403a_94be_fa3a728d0617
type: SpeciesReference
stoichiometry: 1.0
species: metaid s64

http://identifiers.org/biomodels.db/MODEL1303010000#_746c619c_77b2_44f4_8ff3_c3c3aeff67d5
type: SpeciesReference
stoichiometry: 1.0
species: metaid s59

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s62

metaid equilibrate BidT to BidM kf
type: Parameter
constant: true
value: 0.1
name: equilibrate_BidT_to_BidM_kf

metaid bind BadM BclxLM kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_BadM_BclxLM_kf

metaid r12
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r12

http://identifiers.org/biomodels.db/MODEL1303010000#_540b8911_81a5_4d0e_9f97_57d841473a85
type: SpeciesReference
stoichiometry: 1.0
species: metaid s33

http://identifiers.org/biomodels.db/MODEL1303010000#_0b96c04b_b4f0_4cd4_a751_4900db07ede6
type: SpeciesReference
stoichiometry: 1.0
species: metaid s32

http://identifiers.org/biomodels.db/MODEL1303010000#b93a4169_df99_43d5_a389_ae4401876e8c
type: SpeciesReference
stoichiometry: 1.0
species: metaid s10

metaid bind NoxaM Mcl1M kr
type: Parameter
constant: true
value: 0.019
name: bind_NoxaM_Mcl1M_kr

metaid assemble pore sequential Bax 4 kf
type: Parameter
constant: true
value: 2.040816E-4
name: assemble_pore_sequential_Bax_4_kf

metaid catalyze C3APARPU to C3A PARPC kc
type: Parameter
constant: true
value: 1.0
name: catalyze_C3APARPU_to_C3A_PARPC_kc

metaid r52
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r52

http://identifiers.org/biomodels.db/MODEL1303010000#f5c206b4_5d30_4ec5_a1b5_9d543be64c0c
type: SpeciesReference
stoichiometry: 1.0
species: metaid s68

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s67

http://identifiers.org/biomodels.db/MODEL1303010000#_7bfa0089_f341_4851_a5b7_66bdcd47b797
type: SpeciesReference
stoichiometry: 1.0
species: metaid s5

metaid bind Apop XIAP kf
type: Parameter
constant: true
value: 2.0E-6
name: bind_Apop_XIAP_kf

metaid r2
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r2

http://identifiers.org/biomodels.db/MODEL1303010000#_116810f9_bd04_4324_96d5_61c369354e3d
type: SpeciesReference
stoichiometry: 1.0
species: metaid s23

http://identifiers.org/biomodels.db/MODEL1303010000#_716e137e_a61a_4603_9604_c204aea665ea
type: SpeciesReference
stoichiometry: 1.0
species: metaid s16

metaid bind SmacA XIAP kf
type: Parameter
constant: true
value: 7.0E-6
name: bind_SmacA_XIAP_kf

metaid bind BadM Bcl2 kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_BadM_Bcl2_kf

metaid r23
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r23

http://identifiers.org/biomodels.db/MODEL1303010000#_493a0cfa_ea59_42ac_87be_ffde9065247e
type: SpeciesReference
stoichiometry: 1.0
species: metaid s44

http://identifiers.org/biomodels.db/MODEL1303010000#_817bf46e_35fd_444d_90b9_89a5e15d5674
type: SpeciesReference
stoichiometry: 1.0
species: metaid s36

http://identifiers.org/biomodels.db/MODEL1303010000#af0ced58_5052_4a96_8bb2_aa5a9e6927d0
type: SpeciesReference
stoichiometry: 1.0
species: metaid s17

metaid pore transport complex BaxA 4 SmacM kr
type: Parameter
constant: true
value: 0.001
name: pore_transport_complex_BaxA_4_SmacM_kr

metaid pore transport complex BaxA 4 SmacM kf
type: Parameter
constant: true
value: 2.857143E-5
name: pore_transport_complex_BaxA_4_SmacM_kf

metaid r20
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r20

http://identifiers.org/biomodels.db/MODEL1303010000#aab87ea3_6aeb_49e5_9209_c47f9c9ce9f7
type: SpeciesReference
stoichiometry: 1.0
species: metaid s41

http://identifiers.org/biomodels.db/MODEL1303010000#_8d21e49c_ee7c_4cce_ad7f_821fa3b753cc
type: SpeciesReference
stoichiometry: 1.0
species: metaid s36

http://identifiers.org/biomodels.db/MODEL1303010000#_76f28e15_43ca_4710_b39c_923933bd8eea
type: SpeciesReference
stoichiometry: 1.0
species: metaid s14

metaid r9
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r9

http://identifiers.org/biomodels.db/MODEL1303010000#_3d32831e_10fd_4b3b_951b_0c26570b0321
type: SpeciesReference
stoichiometry: 1.0
species: metaid s30

http://identifiers.org/biomodels.db/MODEL1303010000#_0628ab23_874f_461b_97f6_fbd7ba19c36b
type: SpeciesReference
stoichiometry: 1.0
species: metaid s27

http://identifiers.org/biomodels.db/MODEL1303010000#_9d4e862f_203e_44da_86f3_5000f5c95df9
type: SpeciesReference
stoichiometry: 1.0
species: metaid s6

metaid catalyze C3AC6pro to C3A C6A kc
type: Parameter
constant: true
value: 1.0
name: catalyze_C3AC6pro_to_C3A_C6A_kc

metaid pore transport complex BakA 4 CytoCM kr
type: Parameter
constant: true
value: 0.001
name: pore_transport_complex_BakA_4_CytoCM_kr

metaid r35
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r35

http://identifiers.org/biomodels.db/MODEL1303010000#_22cef104_5257_4b01_be61_beb5da430ebb
type: SpeciesReference
stoichiometry: 1.0
species: metaid s55

http://identifiers.org/biomodels.db/MODEL1303010000#_0b8672eb_8aff_40d8_8e43_308844ce2ba1
type: SpeciesReference
stoichiometry: 1.0
species: metaid s47

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type: SpeciesReference
stoichiometry: 1.0
species: metaid s47

metaid r39
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: true
name: r39

http://identifiers.org/biomodels.db/MODEL1303010000#bc30a653_43ea_4d08_b353_b2320b8f2527
type: SpeciesReference
stoichiometry: 1.0
species: metaid s57

http://identifiers.org/biomodels.db/MODEL1303010000#b58049b0_61e0_47c6_9b0c_e0534b0748ce
type: SpeciesReference
stoichiometry: 1.0
species: metaid s55

http://identifiers.org/biomodels.db/MODEL1303010000#_4dd85ad7_2cc3_4a66_8ded_34b4b1c8f6ac
type: SpeciesReference
stoichiometry: 1.0
species: metaid s47

metaid bind C8A C3pro to C8AC3pro kf
type: Parameter
constant: true
value: 1.0E-7
name: bind_C8A_C3pro_to_C8AC3pro_kf

metaid bind C3A PARPU to C3APARPU kr
type: Parameter
constant: true
value: 0.01
name: bind_C3A_PARPU_to_C3APARPU_kr

metaid bind L R to LR kf
type: Parameter
constant: true
value: 4.0E-7
name: bind_L_R_to_LR_kf

metaid r3
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r3

http://identifiers.org/biomodels.db/MODEL1303010000#da541497_542b_4aba_8cb2_e175eb2d4b89
type: SpeciesReference
stoichiometry: 1.0
species: metaid s24

http://identifiers.org/biomodels.db/MODEL1303010000#fde9184b_b4e7_44df_b5dc_b615628a207e
type: SpeciesReference
stoichiometry: 1.0
species: metaid s21

metaid s18
type: Species
is: Q13794
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 1000.0
name: Noxa(bf=None, state=C)

metaid bind BaxA BclxLM kf
type: Parameter
constant: true
value: 1.0E-6
name: bind_BaxA_BclxLM_kf

metaid bind DISC flip kr
type: Parameter
constant: true
value: 0.001
name: bind_DISC_flip_kr

metaid equilibrate BidT to BidM kr
type: Parameter
constant: true
value: 0.001
name: equilibrate_BidT_to_BidM_kr

metaid bind BadM BclxLM kr
type: Parameter
constant: true
value: 0.01
name: bind_BadM_BclxLM_kr

metaid equilibrate BaxC to BaxM kf
type: Parameter
constant: true
value: 0.01
name: equilibrate_BaxC_to_BaxM_kf

metaid pore transport dissociate BaxA 4 SmacC kc
type: Parameter
constant: true
value: 10.0
name: pore_transport_dissociate_BaxA_4_SmacC_kc

metaid bind C6A C8pro to C6AC8pro kf
type: Parameter
constant: true
value: 3.0E-8
name: bind_C6A_C8pro_to_C6AC8pro_kf

metaid catalyze BaxABaxM to BaxA BaxA kc
type: Parameter
constant: true
value: 1.0
name: catalyze_BaxABaxM_to_BaxA_BaxA_kc

metaid pore transport complex BakA 4 SmacM kf
type: Parameter
constant: true
value: 2.857143E-5
name: pore_transport_complex_BakA_4_SmacM_kf

metaid bind C3A C6pro to C3AC6pro kr
type: Parameter
constant: true
value: 0.001
name: bind_C3A_C6pro_to_C3AC6pro_kr

metaid r36
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r36

http://identifiers.org/biomodels.db/MODEL1303010000#_16a81923_7c2e_4b71_93c8_ada2d3953962
type: SpeciesReference
stoichiometry: 1.0
species: metaid s46

http://identifiers.org/biomodels.db/MODEL1303010000#a0734ed8_e492_4650_9953_75bcc012437d
type: SpeciesReference
stoichiometry: 1.0
species: metaid s46

http://identifiers.org/biomodels.db/MODEL1303010000#ee290250_1eea_4b06_baef_80cf4bd3d6b1
type: SpeciesReference
stoichiometry: 1.0
species: metaid s48

metaid r18
type: Reaction
modifier: MODEL1303010000#
fast: false
reversible: false
name: r18

http://identifiers.org/biomodels.db/MODEL1303010000#_4335a924_4cab_41cf_951e_0d7928d111ce
type: SpeciesReference
stoichiometry: 1.0
species: metaid s39

http://identifiers.org/biomodels.db/MODEL1303010000#_1fc65183_8b1a_416f_a79d_794a2969117a
type: SpeciesReference
stoichiometry: 1.0
species: metaid s32

http://identifiers.org/biomodels.db/MODEL1303010000#a47c042c_7e4a_4aa2_82a6_199499a97c46
type: SpeciesReference
stoichiometry: 1.0
species: metaid s35