1-phosphatidyl-1D-myo-inositol 3-phosphate [cell envelope]
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [cell envelope]
glycerol 3-phosphate [endoplasmic reticulum]
nicotinic acid D-ribonucleotide [cytoplasm]
ergosta-5,7,24(28)-trien-3beta-ol [cytoplasm]
3-oxodocosanoyl-CoA [endoplasmic reticulum]
3-hydroxydocosanoyl-CoA [endoplasmic reticulum]
2,3-diketo-5-methylthio-1-phosphopentane degradation reaction
5-(methylsulfanyl)-2,3-dioxopentyl phosphate [cytoplasm]
inositol-P-ceramide B (C26) [mitochondrion]
(S)-3-hydroxyhexacosanoyl-CoA [endoplasmic reticulum]
4-amino-2-methyl-5-diphosphomethylpyrimidine [cytoplasm]
S-adenosyl-4-methylthio-2-oxobutanoate [cytoplasm]
(S)-2-acetyl-2-hydroxybutanoate [mitochondrion]
GENE_ASSOCIATION:((YGL205W and YIL160C and YKR009C and YLR284C) or (YGL205W and YIL160C and YKR009C and YOR180C))
ceramide-2 (C24) [endoplasmic reticulum]
1D-myo-inositol 1-phosphate [endoplasmic reticulum]
inositol-P-ceramide B (C24) [endoplasmic reticulum]
GENE_ASSOCIATION:(YIL009W or YMR246W or YOR317W)
inositol-P-ceramide D (C26) [mitochondrion]
1D-myo-inositol 3-phosphate [mitochondrion]
GENE_ASSOCIATION:(YDR400W and YLR017W and YLR209C)
galactose-1-phosphate uridylyltransferase
alpha-D-galactose 1-phosphate [cytoplasm]
aldehyde dehydrogenase (indole-3-acetaldehyde, NADP)
N-acetyl-alpha-D-glucosamine 1-phosphate [cytoplasm]
dolichyl D-mannosyl phosphate [endoplasmic reticulum]
6-O-[alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
dolichyl phosphate [endoplasmic reticulum]
GPI14:PBN1 [endoplasmic reticulum membrane]
6-(alpha-D-glucosaminyl)-O-acyl-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
P1-(5'-adenosyl),P4-(5'-guanosyl) tetraphosphate [cytoplasm]
7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid [cytoplasm]
5,10-methylenetetrahydrofolate(2-) [mitochondrion]
GENE_ASSOCIATION:(YAL044C and YDR019C and YFL018C and YMR189W)
glutamine-fructose-6-phosphate transaminase
alpha-D-glucosamine 6-phosphate [cytoplasm]
phosphatidyl-L-serine [endoplasmic reticulum]
CDP-diacylglycerol [endoplasmic reticulum]
6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
5-formyltetrahydrofolic acid [cytoplasm]
GENE_ASSOCIATION:(YBR068C or YBR069C or YCL025C or YDR046C or YKR039W)
1-phosphatidyl-1D-myo-inositol 3-phosphate [vacuole]
citrate to cis-aconitate(3-), cytoplasmic
inositol-1,4,5-triphosphate 6-kinase, nucleus
1D-myo-inositol 1,4,5,6-tetrakisphosphate [nucleus]
1D-myo-inositol 1,4,5-trisphosphate [nucleus]
mannose-1D-myo-inositol 1-phosphate [endoplasmic reticulum]
2,3-bisphospho-D-glyceric acid [cytoplasm]
mannose-(1D-myo-inositol 1-phosphate)2 [mitochondrion]
inositol phosphomannosylinositol phosphoceramide B' (C24) [mitochondrion]
5'-S-methyl-5'-thioadenosine [cytoplasm]
inositol-P-ceramide B' (C26) [mitochondrion]
2-(3-amino-3-carboxypropyl)-L-histidine [cytoplasm]
octadecaprenyl diphosphate [lipid particle]
nonadecaprenyl diphosphate [lipid particle]
isopentenyl diphosphate [lipid particle]
5-O-(1-carboxyvinyl)-3-phosphoshikimic acid [cytoplasm]
episteryl palmitoleate [endoplasmic reticulum]
GENE_ASSOCIATION:((Q0080 and Q0085 and Q0130 and YBL099W and YBR039W and YDL004W and YDR298C and YDR322C-A and YDR377W and YJR121W and YKL016C and YLR295C and YML081C-A and YPL078C and YPL271W) or (Q0080 and Q0085 and Q0130 and YBL099W and YBR039W and YDL004W and YDR298C and YDR377W and YJR121W and YKL016C and YLR295C and YML081C-A and YPL078C and YPL271W and YPR020W))
ATP1:ATP14:ATP15:ATP16:ATP17:ATP18:ATP2:ATP3:ATP4:ATP5:ATP6:ATP7:ATP8:OLI1:TIM11 [mitochondrial membrane]
ATP1:ATP14:ATP15:ATP16:ATP17:ATP18:ATP2:ATP20:ATP3:ATP4:ATP5:ATP6:ATP7:ATP8:OLI1 [mitochondrial membrane]
mannosylinositol phosphorylceramide A (C26) [mitochondrion]
ceramide-2' (C26) [endoplasmic reticulum]
3-(4-hydroxyphenyl)pyruvate [mitochondrion]
purine-nucleoside phosphorylase (Guanosine)
GCV1:GCV2:GCV3:PDA1:PDB1 [mitochondrion]
diphosphoinositol-1,3,4,6-tetrakisphosphate synthase
5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate [cytoplasm]
myo-inositol 1,3,4,5,6-pentakisphosphate [cytoplasm]
2-oxo-4-methyl-3-carboxypentanoate decarboxylation
(2S)-2-isopropyl-3-oxosuccinate(2-) [mitochondrion]
4-methyl-2-oxopentanoate [mitochondrion]
mannose-(1D-myo-inositol 1-phosphate)2 [endoplasmic reticulum]
5-diphosphoinositol-1,2,3,4,6-pentakisphosphate synthase
myo-inositol hexakisphosphate [cytoplasm]
5-diphospho-1D-myo-inositol pentakisphosphate [cytoplasm]
inositol phosphomannosylinositol phosphoceramide A (C26) [Golgi]
3-hydroxy-3-methylglutaryl-CoA [cytoplasm]
inositol phosphomannosylinositol phosphoceramide D (C26) [endoplasmic reticulum]
ceramide-4 (C26) [endoplasmic reticulum]
phosphatidyl-N-methylethanolamine [mitochondrion]
ceramide-2' (sphinganine:n-C26:0OH) transport
purine-nucleoside phosphorylase (Xanthosine)
inositol phosphomannosylinositol phosphoceramide D (C24) [endoplasmic reticulum]
ceramide-4 (C24) [endoplasmic reticulum]
GENE_ASSOCIATION:(YBR145W or YDL168W or YGL256W or YMR303C or YOL086C)
aldehyde dehydrogenase (tryptophol, NAD)
phosphoribosylpyrophosphate amidotransferase
1-phosphatidyl-1D-myo-inositol [cell envelope]
(S)-3-methyl-2-oxopentanoate [mitochondrion]
mannosylinositol phosphorylceramide C (C24) [Golgi]
inositol phosphomannosylinositol phosphoceramide C (C24) [Golgi]
2-deoxy-D-ribose 5-phosphate [cytoplasm]
nonaprenyl 4-hydroxybenzoate [cytoplasm]
GENE_ASSOCIATION:(YBR293W or YCL069W or YMR088C)
inositol-P-ceramide A (C24) [mitochondrion]
2-hydroxy-3-oxobutyl phosphate [cytoplasm]
GENE_ASSOCIATION:((YDR178W and YJL045W and YKL141W and YLL041C) or (YDR178W and YKL141W and YKL148C and YLL041C))
2-trans,6-trans-farnesyl diphosphate [cytoplasm]
1-(sn-glycero-3-phospho)-1D-myo-inositol [cytoplasm]
GENE_ASSOCIATION:((Q0105 and YBL045C and YDR529C and YEL024W and YEL039C and YFR033C and YGR183C and YHR001W-A and YJL166W and YOR065W and YPR191W) or (Q0105 and YBL045C and YDR529C and YEL024W and YFR033C and YGR183C and YHR001W-A and YJL166W and YJR048W and YOR065W and YPR191W))
COB:COR1:CYC7:CYT1:QCR10:QCR2:QCR6:QCR7:QCR8:QCR9:RIP1 [mitochondrial membrane]
COB:COR1:CYC1:CYT1:QCR10:QCR2:QCR6:QCR7:QCR8:QCR9:RIP1 [mitochondrial membrane]
palmitoylated Ras protein [endoplasmic reticulum]
protein with N-terminal(Met-Leu) [cytoplasm]
Delta(6)-trans,Delta(8)-cis-leukotriene B4 [nucleus]
acetylated protein with terminal(Met-Ile) [cytoplasm]
protein with N-terminal(Met-Ile) [cytoplasm]
GENE_ASSOCIATION:(YCR020C-A and YEL053C and YPR051W)
mannosylinositol phosphorylceramide A (C26) [Golgi]
(N(omega)-L-arginino)succinic acid [cytoplasm]
GENE_ASSOCIATION:(YLR155C or YLR157C or YLR158C or YLR160C)
inositol-P-ceramide C (C26) [endoplasmic reticulum]
ceramide-3 (C26) [endoplasmic reticulum]
farnesylated protein with methylated C-terminal [endoplasmic reticulum]
farnesylated protein with hydroxyl C-terminal [endoplasmic reticulum]
C-terminal processing of farnesylated proteins II
ergosteryl oleate [endoplasmic reticulum]
3-hydroxyacyl-CoA dehydrogenase (3-oxodecanoyl-CoA)
GENE_ASSOCIATION:(YDR148C and YFL018C and YIL125W)
S(8)-succinyldihydrolipoamide [mitochondrion]
1,2-diacylglycerol 3-diphosphate [cell envelope]
mannose-1D-myo-inositol 1-phosphate [mitochondrion]
mannosylinositol phosphorylceramide B' (C24) [mitochondrion]
ceramide-3 (C24) [endoplasmic reticulum]
episteryl oleate [endoplasmic reticulum]
5-methyltetrahydrofolate(2-) [cytoplasm]
GENE_ASSOCIATION:(YGR037C and YKL182W and YNR016C and YPL231W)
S(8)-aminomethyldihydrolipoamide [mitochondrion]
6-O-{alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
sn-glycero-3-phosphocholine [endoplasmic reticulum]
glycine-cleavage complex (lipoylprotein)
lanosteryl palmitoleate [endoplasmic reticulum]
GENE_ASSOCIATION:(YBR244W or YCL035C or YDR513W or YIR037W or YKL026C)
(Z)-tetradec-7-enoyl-ACP [mitochondrion]
5,10-methylenetetrahydrofolate(2-) [cytoplasm]
methylenetetrahydrofolate dehydrogenase (NAD)
1-acyl-sn-glycerol 3-phosphate [endoplasmic reticulum]
1-acyl-sn-gylcerol-3-phosphate acyltransferase
1-phosphatidylinositol-3-phosphate 5-kinase
3-dehydro-4-methylzymosterol [cytoplasm]
C-3 sterol keto reductase (4-methylzymosterol)
GENE_ASSOCIATION:(YBR069C or YGR191W or YKR039W)
mannosylinositol phosphorylceramide D (C26) [endoplasmic reticulum]
2-trans,6-trans,10-trans-geranylgeranyl diphosphate [cytoplasm]
undecaprenyl diphosphate [lipid particle]
succinate dehydrogenase (FADH2, ubiquinone-6)
3-hydroxyacyl-CoA dehydrogenase (3-oxohexadecanoyl-CoA)
D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate [cytoplasm]
phytosphingosine [endoplasmic reticulum]
N-(5-phospho-beta-D-ribosyl)anthranilate [cytoplasm]
isocitrate dehydrogenase (NADP+), peroxisomal
phosphoribosyl amino imidazolesuccinocarbozamide synthetase
phosphoribosyl-carboxy-aminoimidazole [cytoplasm]
5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole [cytoplasm]
P(1),P(4)-bis(5'-adenosyl) tetraphosphate [cytoplasm]
GENE_ASSOCIATION:((YBR036C and YPL057C) or (YBR036C and YBR161W))
mannosylinositol phosphorylceramide B' (C24) [Golgi]
4beta-methylzymosterol-4alpha-carboxylic acid [cytoplasm]
GENE_ASSOCIATION:(YER070W or YJL026W or YIL066C or YGR180C or (YER070W and YJL026W) or (YER070W and YGR180C) or (YER070W and YJL026W) or (YGR180C and YIL066C))
protein with N-terminal(Met-Phe) [cytoplasm]
5-amino-6-(5-phosphoribitylamino)uracil [cytoplasm]
beta-D-mannosyldiacetylchitobiosyldiphosphodolichol [cytoplasm]
N-acetyl-L-glutamate(2-) [mitochondrion]
henicosaprenyl diphosphate [lipid particle]
docosaprenyl diphosphate [lipid particle]
1D-myo-inositol 4,5-bisphosphate:AVO1:AVO2:BIT61:LST8:SLM1:TOR2:TSC11 [cell envelope]
PI4,5P2:YIL105C binding to TORC2 at plasma membrane
1D-myo-inositol 4,5-bisphosphate:SLM1 [cytoplasm]
AVO1:AVO2:BIT61:LST8:TOR2:TSC11 [cell envelope]
inositol-P-ceramide D (C26) [endoplasmic reticulum]
3-hydroxyacyl-CoA dehydrogenase (3-oxooctadecanoyl-CoA)
1D-myo-inositol 4,5-bisphosphate:AVO1:AVO2:BIT61:LST8:SLM2:TOR2:TSC11 [cell envelope]
N-tetradecanoylglycylpeptide [cytoplasm]
glycylpeptide N-tetradecanoyltransferase
mannosylinositol phosphorylceramide B' (C26) [endoplasmic reticulum]
1-acylglycerophosphocholine [extracellular]
sn-glycero-3-phosphocholine [extracellular]
GENE_ASSOCIATION:(YOL055C or YPL258C or YPR121W)
4-amino-5-hydroxymethyl-2-methylpyrimidine [cytoplasm]
4-amino-2-methyl-5-phosphomethylpyrimidine [cytoplasm]
acetyl-CoA C-acyltransferase (decanoyl-CoA)
aldehyde dehydrogenase (isobutyl alcohol, NAD)
adenosylmethionine-8-amino-7-oxononanoate transaminase
L-aminoadipate-semialdehyde dehydrogenase (NADPH)
C-4 sterol methyl oxidase (4,4-dimethylzymosterol)
inositol-P-ceramide B' (C24) [mitochondrion]
GENE_ASSOCIATION:(YBR126C and YDR074W and (YML100W or YMR261C))
alpha,alpha-trehalose 6-phosphate [cytoplasm]
alpha,alpha-trehalose-phosphate synthase (UDP-forming)
3-hexaprenyl-4,5-dihydroxybenzoic acid [cytoplasm]
2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol [mitochondrion]
GENE_ASSOCIATION:(YJR051W or (YDR178W and YJL045W and YKL141W and YLL041C) or (YDR178W and YKL141W and YKL148C and YLL041C))
mannosylinositol phosphorylceramide C (C24) [endoplasmic reticulum]
inositol-P-ceramide A (C26) [mitochondrion]
glycerol-3-phosphate dehydrogenase (NAD)
dihydroxyacetone phosphate [mitochondrion]
COX1:COX12:COX13:COX2:COX3:COX4:COX5B:COX6:COX7:COX8:COX9:CYC7 [mitochondrial membrane]
COX1:COX12:COX13:COX2:COX3:COX4:COX5B:COX6:COX7:COX8:COX9:CYC1 [mitochondrial membrane]
COX1:COX12:COX13:COX2:COX3:COX4:COX5A:COX6:COX7:COX8:COX9:CYC1 [mitochondrial membrane]
GENE_ASSOCIATION:((Q0045 and Q0250 and Q0275 and YDL067C and YEL039C and YGL187C and YGL191W and YHR051W and YIL111W and YLR038C and YLR395C and YMR256C) or (Q0045 and Q0250 and Q0275 and YDL067C and YEL039C and YGL187C and YGL191W and YHR051W and YLR038C and YLR395C and YMR256C and YNL052W) or (Q0045 and Q0250 and Q0275 and YDL067C and YGL187C and YGL191W and YHR051W and YIL111W and YJR048W and YLR038C and YLR395C and YMR256C) or (Q0045 and Q0250 and Q0275 and YDL067C and YGL187C and YGL191W and YHR051W and YJR048W and YLR038C and YLR395C and YMR256C and YNL052W))
COX1:COX12:COX13:COX2:COX3:COX4:COX5A:COX6:COX7:COX8:COX9:CYC7 [mitochondrial membrane]
farnesyl diphosphate [endoplasmic reticulum]
protein with CAAX motif at C terminal, X={Leu,Phe} [endoplasmic reticulum]
geranylgeranylated protein with AAX motif at C terminal, X={Leu,Phe} [endoplasmic reticulum]
farnesyltransferase to proteins with CAAX motif at C-terminus, where X={ser,cys,Met,ala}
GENE_ASSOCIATION:(YGR087C or YLR044C or YLR134W)
inositol phosphomannosylinositol phosphoceramide B (C24) [mitochondrion]
GENE_ASSOCIATION:(YER056C or YER060W or YER060W-A or YGL186C)
3-hydroxyacyl-CoA dehydrogenase (3-oxohexacosyl-CoA)
(S)-3-hydroxyhexacosanoyl-CoA [peroxisome]
GENE_ASSOCIATION:(YBR068C or YBR069C or YCL025C or YDR046C or YKR039W or YOL020W)
stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA)
5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide [cytoplasm]
1-(5-phospho-D-ribosyl)-5-[(5-phospho-D-ribosylamino)methylideneamino]imidazole-4-carboxamide [cytoplasm]
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase
GENE_ASSOCIATION:((YGR175C and YIL043C and YNL111C) or (YGR175C and YKL150W and YNL111C))
(S)-2,3-epoxysqualene [endoplasmic reticulum]
pantetheine-phosphate adenylyltransferase
2-trans,6-trans-farnesyl diphosphate [mitochondrion]
inositol phosphomannosylinositol phosphoceramide A (C26) [endoplasmic reticulum]
1-phosphatidyl-1D-myo-inositol 3-phosphate [endoplasmic reticulum]
1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
phosphatidylinositol phosphate phosphatase
asparaginyl-tRNA synthetase, miotchondrial
asparagine synthase (glutamine-hydrolysing)
(R)-S-lactoylglutathione [mitochondrion]
GENE_ASSOCIATION:(YLL028W or YGR138C or YPR156C or YOR273C)
dodecaprenyl diphosphate [lipid particle]
(S)-3-methyl-2-oxopentanoate [cytoplasm]
6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
1-pyrroline-3-hydroxy-5-carboxylic acid [mitochondrion]
trans-4-hydroxy-L-proline [mitochondrion]
GENE_ASSOCIATION:(YDR261C or YGR282C or YLR300W or YNR067C or YOR190W)
GENE_ASSOCIATION:(YDL245C or YDR342C or YDR343C or YDR345C or YDR536W or YEL069C or YFL011W or YHR092C or YHR094C or YHR096C or YJL214W or YJL219W or YJR158W or YLR081W or YMR011W or YNR072W or YOL156W or YDL247W or YDL247W)
inositol phosphomannosylinositol phosphoceramide B (C24) [endoplasmic reticulum]
3-hydroxy-2-isopropyl-4-methoxy-4-oxobutanoate [cytoplasm]
1D-myo-inositol 1,3,4,5-tetrakisphosphate [nucleus]
inositol-1,4,5-trisphosphate 3-kinase, nucleus
GENE_ASSOCIATION:((YDR453C and YGR209C) or (YDR453C and YLR043C))
hydrogen peroxide reductase (thioredoxin)
YHR005C, myristoylated at G2, palmitoylated at C3 [cytoplasm]
6-O-phosphono-D-glucono-1,5-lactone [cytoplasm]
ceramide-2' (C24) [endoplasmic reticulum]
heptadecaprenyl diphosphate [lipid particle]
(2S)-2-isopropyl-3-oxosuccinate(2-) [cytoplasm]
Ras protein with CaaX motif at C terminal, a=aliphatic residue, X=any residue [endoplasmic reticulum]
GENE_ASSOCIATION:((YEL039C and YML054C) or (YJR048W and YML054C))
(S)-lactate:ferricytochrome-c 2-oxidoreductase
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid [mitochondrion]
GENE_ASSOCIATION:(YAL044C and YBR221C and YDR019C and YER178W and YMR189W)
5-formyltetrahydrofolic acid [mitochondrion]
alpha-D-glucosamine 1-phosphate [cytoplasm]
ceramide-1 (C24) [endoplasmic reticulum]
nicotinic acid D-ribonucleotide [mitochondrion]
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [mitochondrion]
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [vacuole]
DCI1:ECI1:FOX2:POT1:POX1:SPS19 [peroxisome]
GENE_ASSOCIATION:((YGL205W and YIL160C and YKR009C and YLR284C and YNL202W) or (YGL205W and YIL160C and YKR009C and YLR284C and YNL202W and YOR180C) or (YGL205W and YIL160C and YKR009C and YNL202W and YOR180C))
acetylated protein with terminal(Met-Glu) [cytoplasm]
3-(4-hydroxyphenyl)pyruvate [peroxisome]
3-oxotetracosanoyl-CoA [endoplasmic reticulum]
3-hydroxytetracosanoyl-CoA [endoplasmic reticulum]
pentaprenyl diphosphate [lipid particle]
geranylgeranyl diphosphate [lipid particle]
inositol-P-ceramide B (C24) [mitochondrion]
(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate [mitochondrion]
GENE_ASSOCIATION:(YFL055W or YKR039W or YPL265W)
uroporphyrinogen decarboxylase (uroporphyrinogen III)
mannosylinositol phosphorylceramide B (C26) [Golgi]
inositol phosphomannosylinositol phosphoceramide B (C26) [Golgi]
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [cytoplasm]
GENE_ASSOCIATION:((YGL205W and YIL160C and YKR009C and YLR284C and YNL202W) or (YGL205W and YIL160C and YKR009C and YNL202W and YOR180C))
4-diphospho-1D-myo-inositol pentakisphosphate [cytoplasm]
hexacosanoyl-CoA [endoplasmic reticulum]
GENE_ASSOCIATION:((YHL003C and YMR298W) or (YKL008C and YMR298W))
ceramide-1 (C26) [endoplasmic reticulum]
aldehyde dehydrogenase (2-phenylethanol, NAD)
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [endoplasmic reticulum]
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol [cytoplasm]
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [endoplasmic reticulum]
phosphatidylinositol 4,5-bisphosphate 5-phosphatase
1-phosphatidyl-1D-myo-inositol 4-phosphate [endoplasmic reticulum]
7,8-dihydroneopterin 3'-triphosphate [cytoplasm]
zymosteryl palmitoleate [endoplasmic reticulum]
(S)-3-hydroxypalmitoyl-CoA [endoplasmic reticulum]
sphingoid base-phosphate phosphatase (phytosphingosine 1-phosphate)
phytosphingosine 1-phosphate [endoplasmic reticulum]
lanosteryl oleate [endoplasmic reticulum]
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
inositol phosphomannosylinositol phosphoceramide B (C26) [mitochondrion]
fecosteryl oleate [endoplasmic reticulum]
4,5-bis(diphospho)-1D-myo-inositol tetrakisphosphate [cytoplasm]
2-[3-carboxy-3-(methylammonio)propyl]-L-histidine [cytoplasm]
O-phosphoethanolamine [endoplasmic reticulum]
2-hydroxyhexadecanal [endoplasmic reticulum]
inositol-P-ceramide C (C24) [endoplasmic reticulum]
3-(imidazol-4-yl)-2-oxopropyl dihydrogen phosphate [cytoplasm]
N-acetylglucosamine-6-phosphate synthase
N-acetyl-D-glucosamine 6-phosphate [cytoplasm]
ergosta-5,7,22,24(28)-tetraen-3beta-ol [cytoplasm]
nicotinamide-nucleotide adenylyltransferase
acetylated protein with terminal(Met-Leu) [cytoplasm]
inositol phosphomannosylinositol phosphoceramide B (C26) [endoplasmic reticulum]
deoxyhypusine synthase, cytosolic/mitochondrial
ergosteryl palmitoleate [endoplasmic reticulum]
inositol phosphomannosylinositol phosphoceramide A (C24) [mitochondrion]
sphinganine 1-phosphate [endoplasmic reticulum]
glycerol-3-phosphate/dihydroxyacetone phosphate acyltransferase
dihydroxyacetone phosphate [endoplasmic reticulum]
acylglycerone phosphate [endoplasmic reticulum]
GENE_ASSOCIATION:((YFR015C and YJL137C) or (YFR015C and YKR058W) or (YJL137C and YLR258W) or (YKR058W and YLR258W))
tetracosanoyl-CoA [endoplasmic reticulum]
beta-D-fructose 2,6-bisphosphate [cytoplasm]
S-methyl-5-thio-alpha-D-ribose 1-phosphate [cytoplasm]
GENE_ASSOCIATION:(YBR026C and YER061C and YHR067W and YKL055C and YKL192C and YOR221C)
ACP1:CEM1:ETR1:HTD2:MCT1:OAR1 [mitochondrion]
mannosylinositol phosphorylceramide B (C24) [Golgi]
adenosine 3',5'-bismonophosphate [cytoplasm]
phosphoadenylyl-sulfate reductase (thioredoxin)
3'-phospho-5'-adenylyl sulfate [cytoplasm]
GENE_ASSOCIATION:((YGR209C and YPR167C) or (YLR043C and YPR167C))
heptaprenyl diphosphate [lipid particle]
inositol phosphomannosylinositol phosphoceramide A (C26) [mitochondrion]
5-diphosphoinositol-1,2,3,4,6-pentakisphosphate diphosphohydrolase
3-hydroxyacyl-CoA dehydratase (3-hydroxydecanoyl-CoA)
methylenetetrahydrofolate dehydrogenase (NADP)
3-hydroxy-3-methylglutaryl-CoA [mitochondrion]
saccharopine dehydrogenase (NAD, L-lysine forming)
2-hexaprenyl-6-methoxy-3-methyl-1,4-benzoquinone [mitochondrion]
GENE_ASSOCIATION:(YDR204W and YGL119W and YGR255C and YLR201C and YML110C and YOL096C and YOR125C)
2-hexaprenyl-5-hydroxy-6-methoxy-3-methyl-1,4-benzoquinone [mitochondrion]
CAT5:COQ3:COQ4:COQ5:COQ6:COQ8:COQ9 [mitochondrion]
inositol phosphomannosylinositol phosphoceramide C (C24) [mitochondrion]
1-phosphatidyl-1D-myo-inositol [cytoplasm]
1-phosphatidyl-1D-myo-inositol 4-phosphate [cytoplasm]
beta-D-mannosyldiacetylchitobiosyldiphosphodolichol [Golgi]
3,4-dihydroxy-2-butanone-4-phosphate synthase
inositol phosphomannosylinositol phosphoceramide B' (C26) [mitochondrion]
alpha-D-mannosyl-beta-D-mannosyldiacetylchitobiosyldiphosphodolichol [Golgi]
GENE_ASSOCIATION:(YBR205W or YBR199W or YDR483W or YJL139C or YKR061W or YNL029C or YOR099W or YPL053C)
mannosylinositol phosphorylceramide A (C24) [endoplasmic reticulum]
inositol phosphomannosylinositol phosphoceramide B' (C24) [endoplasmic reticulum]
ceramide-2 (C26) [endoplasmic reticulum]
UDP-N-acetyl-alpha-D-glucosamine [cytoplasm]
GENE_ASSOCIATION:(YBR023C or YBR038W or YNL192W)
4-(phosphonooxy)-L-threonine [cytoplasm]
dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate)
(R)-2,3-dihydroxy-3-methylbutanoate [mitochondrion]
UDP-glucose:ergosterol glucosyltransferase
ergosterol 3-beta-D-glucoside [cytoplasm]
sedoheptulose 1,7-bisphosphate D-glyceraldehyde-3-phosphate-lyase
sedoheptulose 1,7-bisphosphate [cytoplasm]
fatty acyl-CoA synthase (n-C8:0CoA), lumped reaction
inositol phosphomannosylinositol phosphoceramide C (C26) [Golgi]
mannosylinositol phosphorylceramide C (C26) [Golgi]
mannosylinositol phosphorylceramide D (C24) [Golgi]
inositol phosphomannosylinositol phosphoceramide D (C24) [Golgi]
PIB1:phosphatidylinositol 3-phosphate [vacuole]
5'-phosphoribosyl-5-aminoimidazole [cytoplasm]
5-methyltetrahydropteroyltri-L-glutamic acid [cytoplasm]
glycogen vacuolar 'transport' via autophagy
3-hydroxyoctadecanoyl-CoA [endoplasmic reticulum]
5-amino-6-(D-ribitylamino)uracil [cytoplasm]
O-mannosylated protein [endoplasmic reticulum]
PMT1:PMT2 [endoplasmic reticulum membrane]
O-glycosylation of proteins by PMT1:PMT2
secretory protein with appropriate seryl or threonyl group [endoplasmic reticulum]
C-3 sterol dehydrogenase (4-methylzymosterol)
Heavner2012 - Metabolic Network of S.cerevisiae
inositol-P-ceramide C (C26) [mitochondrion]
GENE_ASSOCIATION:((YCR083W and YHR106W) or (YCR083W and YPL091W))
3-hexaprenyl-4-hydroxy-5-methoxybenzoate decarboxylase
2-hexaprenyl-6-methoxyphenol [mitochondrion]
3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid [mitochondrion]
inositol phosphomannosylinositol phosphoceramide A (C24) [Golgi]
mannosylinositol phosphorylceramide A (C24) [Golgi]
but-1-ene-1,2,4-tricarboxylic acid [mitochondrion]
aldehyde dehydrogenase (2-methylbutanol, NADP)
GENE_ASSOCIATION:(YCR105W or YDR368W or YMR318C)
GENE_ASSOCIATION:(YIL002C or YNL106C or YOR109W)
1-phosphatidyl-1D-myo-inositol 4-phosphate [cell envelope]
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [cell envelope]
mannosylinositol phosphorylceramide B (C26) [endoplasmic reticulum]
4PP-IP5 pyrophosphorylation to 4,5-PP2-IP4
protein with N-terminal(Met-Trp) [cytoplasm]
GENE_ASSOCIATION:(YDR380W or YGR087C or YLR044C or YLR134W)
inositol-P-ceramide A (C26) [endoplasmic reticulum]
1-phosphatidyl-1D-myo-inositol 3-phosphate [mitochondrion]
inositol-P-ceramide B' (C24) [endoplasmic reticulum]
tridecaprenyl diphosphate [lipid particle]
6,7-dimethyl-8-(1-D-ribityl)lumazine [cytoplasm]
GENE_ASSOCIATION:((YGR209C and YLR109W) or (YLR043C and YLR109W))
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase (NADPH)
2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine [cytoplasm]
2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone [cytoplasm]
1-acylglycerophosphocholine [mitochondrion]
5'-phosphoribosyl-N-formylglycineamide [cytoplasm]
inositol-P-ceramide B' (C26) [endoplasmic reticulum]
5-phospho-ribosyl-glycineamide [cytoplasm]
GENE_ASSOCIATION:(YDL080C or YDR380W or YGR087C or YLR044C or YLR134W)
ribonucleoside-triphosphate reductase (UTP)
GENE_ASSOCIATION:(YKR089C or YMR313C or YOR081C)
GENE_ASSOCIATION:((YHR007C and YIL043C and YNL111C) or (YHR007C and YKL150W and YNL111C))
cytochrome P450 lanosterol 14-alpha-demethylase (NAD)
1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate [cytoplasm]
3-oxooctadecanoyl-CoA [endoplasmic reticulum]
3-hexaprenyl-4,5-dihydroxybenzoic acid [mitochondrion]
GENE_ASSOCIATION:(YCL025C or YDR508C or YFL055W or YKR039W or YPL265W)
2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase
ribonucleoside-triphosphate reductase (GTP)
inositol-P-ceramide D (C24) [endoplasmic reticulum]
2-deoxy-D-ribofuranose 1-phosphate [cytoplasm]
purine-nucleoside phosphorylase (deoxyguanosine)
phosphatidylcholine [endoplasmic reticulum]
3-hexaprenyl-4-hydroxybenzoic acid [mitochondrion]
alcohol acetyltransferase (isoamyl alcohol)
GENE_ASSOCIATION:(YEL063C or YKR039W or YNL270C)
1-acylglycerophosphocholine [cell envelope]
erythro-4-hydroxy-L-glutamic acid [mitochondrion]
4-amino-4-deoxychorismate(2-) [cytoplasm]
inositol-P-ceramide D (C24) [mitochondrion]
aldehyde dehydrogenase (2-methylbutanol, NAD)
1-(sn-glycero-3-phospho)-1D-myo-inositol [extracellular]
GENE_ASSOCIATION:((YIL043C and YMR015C and YNL111C) or (YKL150W and YMR015C and YNL111C))
STV1:VMA1:VMA10:VMA11:VMA13:VMA16:VMA2:VMA3:VMA4:VMA5:VMA6:VMA7:VMA8 [Golgi membrane]
fatty acyl-ACP synthase (n-C8:0ACP), lumped reaction
1-C-(indol-3-yl)glycerol 3-phosphate [cytoplasm]
pentadecaprenyl diphosphate [lipid particle]
inositol phosphomannosylinositol phosphoceramide A (C24) [endoplasmic reticulum]
inositol-1,3,4,5-triphosphate 6-kinase, nucleus
myo-inositol 1,3,4,5,6-pentakisphosphate [nucleus]
6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
phosphatidylethanolamine [endoplasmic reticulum]
3-hexaprenyl-4-hydroxybenzoic acid [cytoplasm]
3-hexaprenyl-4,5-dihydroxybenzoate hydroxylase
1-acyl-sn-glycerol 3-phosphate [lipid particle]
alcohol dehydrogenase, reverse rxn (acetaldehyde -> ethanol)
D-erythrose 4-phosphate(2-) [mitochondrion]
3-oxohexacosanoyl-CoA [endoplasmic reticulum]
3',5'-cyclic-nucleotide phosphodiesterase
orotidine 5'-(dihydrogen phosphate) [cytoplasm]
alcohol acetyltransferase (phenylethanol alcohol)
erythro-4-hydroxy-L-glutamic acid [peroxisome]
L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase
4-hydroxy-2-oxoglutarate(2-) [peroxisome]
6-O-{2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
alcohol acetyltransferase (isobutyl alcohol)
mannosylinositol phosphorylceramide A (C24) [mitochondrion]
acetyl-CoA C-acetyltransferase (dodecanoyl)
7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid [mitochondrion]
1-pyrroline-3-hydroxy-5-carboxylic acid [cytoplasm]
S(8)-aminomethyldihydrolipoylprotein [mitochondrion]
protein with dicysteine at C-terminal [cytoplasm]
dihydroneopterin monophosphate dephosphorylase
7,8-dihydroneopterin 3'-phosphate [cytoplasm]
N,N'-diacetylchitobiosyldiphosphodolichol [cytoplasm]
glycinamide ribonucleotide transformylase
3-hydroxyacyl-CoA dehydratase (3-hydroxyhexacosyl-CoA)
acetyl-CoA acyltransferase (tetradecanoyl-CoA)
3-ketosphinganine [endoplasmic reticulum]
5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase
tetrahydropteroyltri-L-glutamic acid [cytoplasm]
3-oxotetradecanoyl-CoA [endoplasmic reticulum]
(S)-3-hydroxytetradecanoyl-CoA [endoplasmic reticulum]
alpha-D-ribose 1-phosphate [mitochondrion]
5,10-methylenetetrahydrofolatereductase (NADPH)
2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate [cytoplasm]
trans-2,3-didehydroacyl-CoA [endoplasmic reticulum]
phosphatidylinositol 3-phosphate phosphatase
GENE_ASSOCIATION:(YJR110W or YNL106C or YOR109W)
1-phosphatidyl-1D-myo-inositol 3-phosphate [cytoplasm]
inositol phosphomannosylinositol phosphoceramide B' (C24) [Golgi]
phosphatidylinositol 3,5-bisphosphate phosphatase
aldehyde dehydrogenase (acetylaldehyde, NAD)
GENE_ASSOCIATION:((YBR058C-A and YDR062W and YMR296C) or (YDR062W and YMR296C))
2-acetamido-5-oxopentanoate [mitochondrion]
N-acetyl-L-gamma-glutamyl phosphate [mitochondrion]
aldehyde dehydrogenase (acetaldehyde, NADP)
VMA1:VMA10:VMA11:VMA13:VMA16:VMA2:VMA3:VMA4:VMA5:VMA6:VMA7:VMA8:VPH1 [vacuolar membrane]
GENE_ASSOCIATION:(YBR127C and YDL185W and YEL027W and YEL051W and YGR020C and YHR026W and YHR039C-A and YKL080W and YLR447C and YOR270C and YOR332W and YPL234C and YPR036W)
inositol-1,3,4,5,6-pentakisphosphate 2-kinase
D-fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase
dolichyl-phosphate D-mannosyltransferase
4-hydroxy-2-oxoglutarate(2-) [cytoplasm]
inositol phosphomannosylinositol phosphoceramide D (C26) [mitochondrion]
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [cytoplasm]
inositol phosphomannosylinositol phosphoceramide D (C26) [Golgi]
pyruvate decarboxylase (acetoin-forming)
inositol-1,4,5,6- tetrakisphosphate 3-kinase, nucleus
adenosine 3',5'-bismonophosphate [mitochondrion]
pantetheine 4'-phosphate [mitochondrion]
5-formyltetrahydrofolic acid [extracellular]
acetylated protein with terminal(Met-Phe) [cytoplasm]
glycerophosphatidylethanolamine [cell envelope]
phosphatidylethanolamine [cell envelope]
erythro-4-hydroxy-L-glutamic acid [cytoplasm]
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [nucleus]
(R)-lactate:ferricytochrome-c 2-oxidoreductase
GENE_ASSOCIATION:((YDL174C and YEL039C) or (YDL174C and YJR048W) or (YEL039C and YEL071W) or (YEL071W and YJR048W))
mannosylinositol phosphorylceramide D (C24) [mitochondrion]
geranylgeranylated protein with methylated C-terminal [endoplasmic reticulum]
S-methyl-5-thio-D-ribulose 1-phosphate [cytoplasm]
5'-phosphoribosyl-N-formylglycineamidine [cytoplasm]
3-hexaprenyl-4,5-dihydroxybenzoate transport
nicotinate-nucleotide diphosphorylase (carboxylating)
mannosylinositol phosphorylceramide B' (C26) [mitochondrion]
L-4-hydroxyglutamic semialdehyde [mitochondrion]
mannosylinositol phosphorylceramide B' (C24) [endoplasmic reticulum]
LAT1:LPD1:PDA1:PDB1:PDX1 [mitochondrion]
(R)-5-diphosphomevalonic acid [cytoplasm]
mannosylinositol phosphorylceramide B (C24) [endoplasmic reticulum]
S-adenosyl-methionine delta-24-sterol-c-methyltransferase
mannosylinositol phosphorylceramide A (C26) [endoplasmic reticulum]
1D-myo-inositol 4,5-bisphosphate:SLM2 [cytoplasm]
protein with N-terminal(Met-Glu) [cytoplasm]
inositol phosphomannosylinositol phosphoceramide C (C26) [endoplasmic reticulum]
phosphopantothenoylcysteine decarboxylase
N-[(R)-4-phosphonopantothenoyl]-L-cysteine [cytoplasm]
acetylated protein with terminal(Met-Trp) [cytoplasm]
mannosylinositol phosphorylceramide D (C26) [Golgi]
protein with CAAX motif at C terminal, X={Ser,Cys,Met,Ala} [endoplasmic reticulum]
acylation of GPI inositol at 2 position, GPI-anchor assembly, step 3
GENE_ASSOCIATION:(YBR069C or YCL025C or YDR046C or YDR508C or YKR039W)
5PP-IP5 pyrophosphorylation to 4,5-PP2-IP4
succinate-semialdehyde dehydrogenase (NADP)
1,2-dioleoyl-sn-glycero-3-phosphocholine [endoplasmic reticulum]
palmitoleoyl-CoA [endoplasmic reticulum]
mannosylinositol phosphorylceramide B' (C26) [Golgi]
inositol phosphomannosylinositol phosphoceramide B' (C26) [endoplasmic reticulum]
GENE_ASSOCIATION:(YCL040W or YFR053C or YGL253W)
inositol-P-ceramide B (C26) [endoplasmic reticulum]
3-hydroxyacyl-CoA dehydratase (3-hydroxydodecanoyl-CoA)
S-adenosyl-L-homocysteine [mitochondrion]
phosphatidyl-N,N-dimethylethanolamine [mitochondrion]
glycerophosphodiester phosphodiesterase (glycerophosphocholine)
S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase
zymosteryl oleate [endoplasmic reticulum]
mannosylinositol phosphorylceramide B (C26) [mitochondrion]
5-(2-hydroxyethyl)-4-methylthiazole [cytoplasm]
6-diphospho-1D-myo-inositol pentakisphosphate [cytoplasm]
S-adenosyl-L-homocysteine [endoplasmic reticulum]
phosphatidylethanolamine methyltransferase
S-adenosyl-L-methionine [endoplasmic reticulum]
phosphatidyl-N-methylethanolamine [endoplasmic reticulum]
spontaneous cis-aconitate(3-) to trans-aconitate
2-oxoadipate and 2-oxoglutarate transport
aldehyde dehydrogenase (phenylacetaldehyde, NAD)
GENE_ASSOCIATION:(YBL030C or YBR085W or YMR056C)
dehydro-D-arabinono-1,4-lactone [cytoplasm]
purine-nucleoside phosphorylase (adenosine)
aldehyde dehydrogenase (isobutyl alcohol, NADP)
1-phosphatidyl-1D-myo-inositol [mitochondrion]
5,6,7,8-tetrahydrofolyl-L-glutamic acid [cytoplasm]
sphingolipid long chain base kinase (sphinganine)
D-sorbitol dehydrogenase (D-fructose producing)
mannosylinositol phosphorylceramide D (C26) [mitochondrion]
phosphatidylethanolamine [mitochondrion]
4-methyl-5-(2-phosphonooxyethyl)thiazole [cytoplasm]
inositol phosphomannosylinositol phosphoceramide C (C26) [mitochondrion]
1-phosphatidyl-1D-myo-inositol [nucleus]
inositol phosphomannosylinositol phosphoceramide B (C24) [Golgi]
tetradecaprenyl diphosphate [lipid particle]
YHR005C, myristoylated at G2 [cytoplasm]
fecosteryl palmitoleate [endoplasmic reticulum]
aldehyde dehydrogenase (indole-3-acetaldehyde, NAD)
GENE_ASSOCIATION:(YDR353W or (YDR353W and YGR209C) or (YDR353W and YLR043C))
5-methylthioribose-1-phosphate isomerase
formate dehydrogenase, cytosolic/mitochondrial
coproporphyrinogen oxidase (O2 required)
sphingoid base-phosphate phosphatase (sphinganine 1-phosphatase)
Aminoacetone:oxygen oxidoreductase(deaminating)(flavin-containing)
hypoxanthine phosphoribosyltransferase (Hypoxanthine)
inositol-P-ceramide A (C24) [endoplasmic reticulum]
L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase
(R)-4'-phosphopantothenic acid [cytoplasm]
L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)
GENE_ASSOCIATION:(YBR132C or YHL016C or YKR039W or YLL028W or YPL274W or YOR273C)
GENE_ASSOCIATION:(YDR536W or YGL084C or YPL189W)
purine-nucleoside phosphorylase (deoxyadenosine)
GENE_ASSOCIATION:(YKL127W or YMR105C or YMR278W)
(2E)-3-(methoxycarbonyl)pent-2-enedioic acid [cytoplasm]
3-phosphoshikimate 1-carboxyvinyltransferase
UDPglucose--hexose-1-phosphate uridylyltransferase
palmitoylated YEL013W [vacuolar membrane]
Delta(6)-trans,Delta(8)-cis-leukotriene B4 [cytoplasm]
mannosylinositol phosphorylceramide C (C26) [endoplasmic reticulum]
mannosylinositol phosphorylceramide B (C24) [mitochondrion]
GENE_ASSOCIATION:(YCL025C or YDR508C or YKR039W or YPL265W)
4-hydroxy-2-oxoglutarate(2-) [mitochondrion]
cytochrome P450 lanosterol 14-alpha-demethylase (NADP)
farnesylated protein with AAX motif at C terminal, X={Ser,Cys,Met,Ala} [endoplasmic reticulum]
GENE_ASSOCIATION:(YBR068C or YCL025C or YDR046C or YKR039W or YOL020W or YOR348C or YPL265W)
2-hexaprenyl-6-methoxy-1,4-benzoquinone [mitochondrion]
1,2-dioleoylglycerol [endoplasmic reticulum]
GENE_ASSOCIATION:(YFL001W or YGL063W or YNL292W or YPL212C)
ceramide-3 (Phytosphingosine:n-C26:0OH) transport
1-pyrroline-5-carboxylate [mitochondrion]
mannosylinositol phosphorylceramide C (C24) [mitochondrion]
1-phosphatidyl-1D-myo-inositol 4-phosphate [Golgi]
3-hydroxyacyl-CoA dehydratase (3-hydroxyoctadecanoyl-CoA)
3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase
3-hydroxyacyl-CoA dehydratase (3-hydroxyhexadecanoyl-CoA)
inositol phosphomannosylinositol phosphoceramide B' (C26) [Golgi]
aldehyde dehydrogenase (isoamyl alcohol, NADP)
dolichyl-phosphate-mannose--protein mannosyltransferase
GENE_ASSOCIATION:(YDL093W or YJR143C or YOR321W or (YAL023C and YDL095W))
GPI-anchor assembly, step 11, deacylation reaction as part of glycosylation
ceramide-2' (sphinganine:n-C24:0OH) transport
protein with GPI signal [endoplasmic reticulum membrane]
geranylgeranylated protein with hydroxyl C-terminal [endoplasmic reticulum]
C-terminal processing of geranylgeranylated proteins I
3-methyl-2-oxobutanoate hydroxymethyltransferase
carbamoyl-phosphate synthase (glutamine-hydrolysing)
GENE_ASSOCIATION:(YJL130C or (YJR109C and YOR303W))
GENE_ASSOCIATION:(YBR298C or YDL247W or YGR289C or YDL247W)
P(1),P(4)-bis(5'-guanosyl) tetraphosphate [cytoplasm]
GENE_ASSOCIATION:(YGR192C or YJL052W or YJR009C)
glyceraldehyde-3-phosphate dehydrogenase
L-4-hydroxyglutamate semialdehyde dehydrogenase
GENE_ASSOCIATION:(YDL042C or YDR191W or YOL068C or YOR025W or YPL015C)
aldehyde dehydrogenase (isoamyl alcohol, NAD)
GENE_ASSOCIATION:((YAL044C and YDR019C and YFL018C and YMR189W) or (YDR148C and YFL018C and YIL125W))
GENE_ASSOCIATION:(YBR068C or YBR069C or YDR046C or YKR039W or YOL020W)
acetyl-CoA acyltransferase (hexadecanoyl-CoA)
L-aminoadipate-semialdehyde dehydrogenase (NADH)
diphosphoinositol-1,3,4,6-tetrakisphosphate diphosphohydrolase
GENE_ASSOCIATION:(YBR068C or YCL025C or YDR046C or YKR039W or YOL020W)
GPI-anchor assembly, step 10, GPI-modification of newly synthesised protein
GENE_ASSOCIATION:(YDR302W and YDR434W and YHR188C and YLR088W and YLR459W)
GAA1:GAB1:GPI16:GPI17:GPI8 [endoplasmic reticulum]
5-formethyltetrahydrofolate cyclo-ligase
3-hydroxyacyl-CoA dehydrogenase (3-oxotetradecanoyl-CoA)
(S)-3-hydroxytetradecanoyl-CoA [peroxisome]
phosphatidylinositol-4-phosphate 5-kinase
1-phosphatidyl-1D-myo-inositol 4-phosphate [nucleus]
nicotinate-nucleotide adenylyltransferase
icosaprenyl diphosphate [lipid particle]
GENE_ASSOCIATION:(YBR127C and YDL185W and YEL027W and YEL051W and YGR020C and YHR026W and YHR039C-A and YKL080W and YLR447C and YMR054W and YOR332W and YPL234C and YPR036W)
5-methylthio-5-deoxy-D-ribulose 1-phosphate dehydratase
6PP-IP5 pyrophosphorylation to 5,6-PP2-IP4
GENE_ASSOCIATION:(YCR034W and YDL015C and YLR372W)
2-keto-4-methylthiobutyrate transamination
mannosylinositol phosphorylceramide C (C26) [mitochondrion]
GENE_ASSOCIATION:(YDR376W and YER141W and YPL252C)
hexadecaprenyl diphosphate [lipid particle]
5PP-IP5 pyrophosphorylation to 5,6-PP2-IP4
fatty acid synthase (n-C24:0), lumped reaction
3-hydroxyacyl-CoA [endoplasmic reticulum]
1-phosphatidyl-1D-myo-inositol [vacuole]
GENE_ASSOCIATION:(YBR221C and YER178W and YFL018C and YGR193C and YNL071W)
UTP-glucose-1-phosphate uridylyltransferase
xylitol dehydrogenase (D-xyulose-forming)
saccharopine dehydrogenase (NADP, L-glutamate forming)
ribonucleoside-triphosphate reductase (CTP)
GENE_ASSOCIATION:((YEL039C and YKR066C) or (YJR048W and YKR066C))
ferrocytochrome-c:hydrogen-peroxide oxidoreductase
L-sorbitol dehydrogenase (L-sorbose-producing)
GENE_ASSOCIATION:((YCR024C-A and YEL017C-A and YGL008C) or (YCR024C-A and YEL017C-A and YPL036W))
GENE_ASSOCIATION:(YCL025C or YFL055W or YKR039W or YPL265W)
acetyl-CoA C-acetyltransferase (octanoyl-CoA)
oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase)
GENE_ASSOCIATION:((YCL035C and YPL091W) or (YDR098C and YPL091W) or (YDR513W and YPL091W) or (YER174C and YPL091W))
tryptophan synthase (indoleglycerol phosphate)
dihydroxyacetone phosphate [lipid particle]
acylglycerone phosphate [lipid particle]
GENE_ASSOCIATION:(YCL025C or YKR039W or YOL020W or YOR348C or YPL265W)
2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase
(2R,3R)-2,3-dihydroxy-3-methylpentanoate [mitochondrion]
dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate)
phosphoribosyl-formamido-carboxamide [cytoplasm]
aldehyde dehydrogenase (2-phenylethanol, NADP)
sn-glycero-3-phosphocholine [cell envelope]
inositol phosphomannosylinositol phosphoceramide D (C24) [mitochondrion]
GENE_ASSOCIATION:(YGL205W and YIL160C and YKR009C)
3-hydroxyacyl-CoA dehydratase (3-hydroxytetradecanoyl-CoA)
diacylglycerol pyrophosphate phosphatase
ERF2:SHR5 [endoplasmic reticulum membrane]
C-terminal processing of geranylgeranylated proteins II
5'-phosphoribosylformyl glycinamidine synthetase
ergosta-5,7,22,24(28)-tetraen-3beta-ol [endoplasmic reticulum]
1D-myo-inositol 4,5-bisphosphate [cytoplasm]
ribonucleoside-triphosphate reductase (ATP)
inositol phosphomannosylinositol phosphoceramide C (C24) [endoplasmic reticulum]
3-oxopalmitoyl-CoA [endoplasmic reticulum]
GENE_ASSOCIATION:((YHL011C and YKL181W) or (YER099C and YOL061W) or (YBL068W and YOL061W))
GENE_ASSOCIATION:(YDL245C or YDR342C or YDR343C or YDR345C or YEL069C or YFL011W or YHR092C or YHR094C or YHR096C or YJL214W or YJL219W or YJR158W or YMR011W or YNR072W or YOL156W)
1-phosphatidyl-1D-myo-inositol 4-phosphate [mitochondrion]
1-phosphatidyl-1D-myo-inositol 4-phosphate [vacuole]
GENE_ASSOCIATION:(YBR296C or YCR037C or YJL198W or YML123C or YNR013C)
mannosylinositol phosphorylceramide D (C24) [endoplasmic reticulum]
fatty acid oxidation (tetradecansoyl-CoA)
acetyl-CoA acyltransferase (tetracosanoyl-CoA)
PI4,5P2:YNL047C binding to TORC2 at plasma membrane
L-glutamic 5-semialdehyde [mitochondrion]
3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate [mitochondrion]
GENE_ASSOCIATION:((YDL178W and YEL039C) or (YDL178W and YJR048W))
GENE_ASSOCIATION:((YGR209C and YIL010W) or (YIL010W and YLR043C))
alcohol acetyltransferase (2-methylbutanol)
sphingolipid long chain base kinase (phytosphingosine)
aldehyde dehydrogenase (acetylaldehyde, NADP)
Heavner2012 - Metabolic Network of S.cerevisiae This SBML representation of the yeast metabolic network is made available under the Creative Commons Attribution-Share Alike 3.0 Unported Licence (see www.creativecommons.org). This model is described in the article: Yeast 5 - an expanded reconstruction of the Saccharomyces cerevisiae metabolic network. Heavner BD, Smallbone K, Barker B, Mendes P, Walker LP. BMC Syst Biol. 2012 Jun 4;6:55. Abstract: BACKGROUND: Efforts to improve the computational reconstruction of the Saccharomyces cerevisiae biochemical reaction network and to refine the stoichiometrically constrained metabolic models that can be derived from such a reconstruction have continued since the first stoichiometrically constrained yeast genome scale metabolic model was published in 2003. Continuing this ongoing process, we have constructed an update to the Yeast Consensus Reconstruction, Yeast 5. The Yeast Consensus Reconstruction is a product of efforts to forge a community-based reconstruction emphasizing standards compliance and biochemical accuracy via evidence-based selection of reactions. It draws upon models published by a variety of independent research groups as well as information obtained from biochemical databases and primary literature. RESULTS: Yeast 5 refines the biochemical reactions included in the reconstruction, particularly reactions involved in sphingolipid metabolism; updates gene-reaction annotations; and emphasizes the distinction between reconstruction and stoichiometrically constrained model. Although it was not a primary goal, this update also improves the accuracy of model prediction of viability and auxotrophy phenotypes and increases the number of epistatic interactions. This update maintains an emphasis on standards compliance, unambiguous metabolite naming, and computer-readable annotations available through a structured document format. Additionally, we have developed MATLAB scripts to evaluate the model's predictive accuracy and to demonstrate basic model applications such as simulating aerobic and anaerobic growth. These scripts, which provide an independent tool for evaluating the performance of various stoichiometrically constrained yeast metabolic models using flux balance analysis, are included as Additional files 1, 2 and 3. CONCLUSIONS: Yeast 5 expands and refines the computational reconstruction of yeast metabolism and improves the predictive accuracy of a stoichiometrically constrained yeast metabolic model. It differs from previous reconstructions and models by emphasizing the distinction between the yeast metabolic reconstruction and the stoichiometrically constrained model, and makes both available as Additional file 4 and Additional file 5 and at http://yeast.sf.net/ as separate systems biology markup language (SBML) files. Through this separation, we intend to make the modeling process more accessible, explicit, transparent, and reproducible. This model is hosted on BioModels Database and identified by: MODEL1209060000 . To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. PMID: 20587024 . To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to [CC0 Public Domain Dedication>http://creativecommons.org/publicdomain/zero/1.0/] for more information.
inositol-P-ceramide C (C24) [mitochondrion]
hexaprenyldihydroxybenzoate methyltransferase
GENE_ASSOCIATION:(YBR068C or YBR069C or YCL025C or YDR046C or YDR508C or YKR039W or YOL020W)
fatty acid synthase (n-C8:0), lumped reaction
ceramide-3 (Phytosphingosine:n-C24:0OH) transport
3-oxoicosanoyl-CoA [endoplasmic reticulum]
purine-nucleoside phosphorylase (inosine)
phosphoribosylaminoimidazolecarboxamide formyltransferase
purine-nucleoside phosphorylase (deoxyinosine)
GENE_ASSOCIATION:(YBR068C or YBR069C or YCL025C or YDR046C or YDR508C or YKR039W)
D1-pyrroline-5-carboxylate dehydrogenase
GENE_ASSOCIATION:(YBR299W or YGR287C or YGR292W)
glycerol-3-phosphate dehydrogenase (fad)
GENE_ASSOCIATION:(YHR216W or YLR432W or YML056C)
3-hydroxyicosanoyl-CoA [endoplasmic reticulum]
2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase
tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming)
GENE_ASSOCIATION:(YDR384C or YGR121C or YNL142W or YPR138C)
GENE_ASSOCIATION:(YBR068C or YCL025C or YDR046C or YDR508C or YGR055W or YHL036W or YKR039W)
ketol-acid reductoisomerase (2-aceto-2-hydroxybutanoate)
aldehyde dehydrogenase (3-aminopropanal, NAD)
C-terminal processing of farnesylated proteins I
NADH dehydrogenase, cytosolic/mitochondrial
2-hexaprenyl-6-methoxyphenol monooxygenase
GENE_ASSOCIATION:(YLR237W or YOR071C or YOR192C)
palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA)
GENE_ASSOCIATION:(YDR536W or YFL011W or YJL219W or YLR081W or YNL318C or YOL156W)