Warning: Species concentration PPi_r is out of the soft bounds.
(S)-3-Hydroxyhexadecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.35 EC:1.1.1.211
ATP-binding Cassette (ABC) TCDB:3.A.1.201.2
fatty acid synthase Polyunsaturated fatty acid biosynthesis EC:2.3.1.85
Error: Species concentration Dihomo-gamma-linolenoyl-CoA_r is out of the hard bounds.
Error: Species concentration Adenylosuccinate_c is out of the hard bounds.
Warning: Species concentration Glycocholate_b is out of the soft bounds.
Error: Species concentration Dopamine_s is out of the hard bounds.
Warning: Species concentration Citrulline_c is out of the soft bounds.
(S)-3-Hydroxybutanoyl-CoA:NAD+ oxidoreductase Fatty acid metabolism / Lysine degradation / Tryptophan metabolism / Butanoate metabolism EC:1.1.1.35
Warning: Species concentration thromboxane-b2_s is out of the soft bounds.
Error: Species concentration GDP-activated-fucose_c is out of the hard bounds.
Warning: Species concentration ApoC2_c is out of the soft bounds.
Hydorogen-peroxide:hydrogen-peroxide oxidoreductase Methane metabolism EC:1.11.1.7
Error: Species concentration sulfotaurolithocholate_s is out of the hard bounds.
Resistance-Nodulation-Cell Division (RND) TCDB:2.A.60.1.5
Warning: Species concentration AMP_p is out of the soft bounds.
Mitochondrial Carrier (MC) TCDB:2.A.29.2.2
Warning: Species concentration Collagen_ITA2_c is out of the soft bounds.
Dihydrofolate:NAD+ oxidoreductase Folate biosynthesis EC:1.5.1.3
Warning: Species concentration ApoTransferin_c is out of the soft bounds.
Error: Species concentration UDP-glucose_s is out of the hard bounds.
Error: Species concentration 2-Aminoadipate_6-semialdehyde_c is out of the hard bounds.
Warning: Species concentration 3,4-Dihydroxymandelate_m is out of the soft bounds.
Amino Acid-Polyamine-Organocation (APC) TCDB:2.A.3.8.15
Warning: Species concentration Collagen_CO4A4_c is out of the soft bounds.
Warning: Species concentration Glucose-1P_s is out of the soft bounds.
Warning: Species concentration Glucosamine_s is out of the soft bounds.
Cysteamine:oxygen oxidoreductase Taurine and hypotaurine metabolism EC:1.13.11.19
Error: Species concentration Lysine_l is out of the hard bounds.
Warning: Species concentration L-Fuculose_c is out of the soft bounds.
Warning: Species concentration Thymidine_c is out of the soft bounds.
Amino Acid-Polyamine-Organocation (APC) TCDB:2.A.3.8.1
Error: Species concentration Cholate_s is out of the hard bounds.
2'-Deoxyadenosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase Purine metabolism EC:1.17.4.1
Palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) Sphingolipid metabolism EC:2.3.1.50
Warning: Species concentration Collagen_VWA2_c is out of the soft bounds.
(S)-3-Hydroxydodecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.211 EC:1.1.1.35
Warning: Species concentration Lactose-6P_s is out of the soft bounds.
Error: Species concentration Betaine_aldehyde_c is out of the hard bounds.
Error: Species concentration Asparagine_s is out of the hard bounds.
Warning: Species concentration (2E)-Dodecenoyl-CoA_p is out of the soft bounds.
Error: Species concentration Adenosine_s is out of the hard bounds.
(3R)-3-Hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase Fatty acid biosynthesis EC:2.3.1.85
Error: Species concentration 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate_c is out of the hard bounds.
Error: Species concentration 7alpha-Hydroxycholest-4-en-3-one_r is out of the hard bounds.
Mitochondrial Carrier (MC) TCDB:2.A.29.19.1
Error: Species concentration Ceramide-pool_r is out of the hard bounds.
Glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating) Fatty acid metabolism EC:1.3.99.7
3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al:NAD+ oxidoreductase Bile acid biosynthesis EC:1.2.1.3
(S)-3-Hydroxyhexadecanoyl-CoA hydro-lyase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:4.2.1.17
Error: Species concentration sulfochenodeoxycholate_s is out of the hard bounds.
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase Purine metabolism EC:4.1.1.21
Warning: Species concentration Porphobilinogen_c is out of the soft bounds.
Warning: Species concentration Choline_c is out of the soft bounds.
Warning: Species concentration 20-hydroxy-arachidonate_s is out of the soft bounds.
glutathione:NADP+ oxidoreductase Glutamate metabolism / Glutathione metabolism EC:1.8.1.7
Warning: Species concentration O2_c is out of the soft bounds.
Organic anion transporter 5 Utilized transport
D-Mannose-6-phosphate ketol-isomerase EC:5.3.1.8
Error: Species concentration CoA_m is out of the hard bounds.
Warning: Species concentration Acetate_m is out of the soft bounds.
Warning: Species concentration 5-Aminolevulinate_m is out of the soft bounds.
Uridine triphosphate pyrophosphohydrolase Pyrimidine metabolism EC:3.6.1.19
Warning: Species concentration Cholesterol-ester-ol_l is out of the soft bounds.
Warning: Species concentration (2E)-Dodecenoyl-CoA_m is out of the soft bounds.
Warning: Species concentration glutathionyl-leuc4_s is out of the soft bounds.
Error: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA_p is out of the hard bounds.
Warning: Species concentration Propinol_adenylate_c is out of the soft bounds.
Warning: Species concentration Protoporphyrin_m is out of the soft bounds.
Warning: Species concentration CoA-activated_acetyl_group_c is out of the soft bounds.
Error: Species concentration 5beta-Cholestane-3alpha,7alpha,26-triol_m is out of the hard bounds.
Error: Species concentration H2O_l is out of the hard bounds.
Warning: Species concentration 3-Oxododecanoyl-CoA_p is out of the soft bounds.
3-Oxopropanoate:NAD+ oxidoreductase (decarboxylating, CoA-acetylating) Propanoate metabolism EC:1.2.1.18
Adenosine 5'-monophosphate phosphohydrolase Purine metabolism EC:3.1.3.5
NADH:ferricytochrome-b5 oxidoreductase Aminosugars metabolism EC:1.6.2.2
Error: Species concentration Acetyl-CoA_p is out of the hard bounds.
Warning: Species concentration Galactosylglycerol_s is out of the soft bounds.
Warning: Species concentration NADP+_r is out of the soft bounds.
Error: Species concentration UDP-activated-glucuronate_c is out of the hard bounds.
Error: Species concentration beta-Alanine_m is out of the hard bounds.
Error: Species concentration O-Acetylcarnitine_m is out of the hard bounds.
Hoppe2012 - Predicting changes in metabolic function using transcript profiles
Formylkynurenine hydrolase Tryptophan metabolism EC:3.7.1.3
Error: Species concentration CO2_s is out of the hard bounds.
Resistance-Nodulation-Cell Division (RND) TCDB:2.A.60.1.2
Error: Species concentration Aspartate_c is out of the hard bounds.
Sedoheptulose 1,7-bisphosphate D-glyceraldehyde-3-phosphate-lyase Carbon fixation EC:4.1.2.13
acetyl-CoA:[acyl-carrier-protein] S-acetyltransferase Fatty acid biosynthesis EC:2.3.1.85
Error: Species concentration Inosine_c is out of the hard bounds.
ATP:adenylylsulfate 3'-phosphotransferase Purine metabolism / Sulfur metabolism EC:2.7.1.25
Warning: Species concentration UMP_s is out of the soft bounds.
Error: Species concentration Glucose_s is out of the hard bounds.
Acetyl-CoA:carnitine O-acetyltransferase Alanine and aspartate metabolism EC:2.3.1.7
Error: Species concentration UroporphyrinogenI_s is out of the hard bounds.
Error: Species concentration Adenylyl_sulfate_c is out of the hard bounds.
Warning: Species concentration Malonyl-CoA_c is out of the soft bounds.
Error: Species concentration Hexadecenal_c is out of the hard bounds.
Error: Species concentration CMP-activated-N-acetylneuraminate_n is out of the hard bounds.
Error: Species concentration 3-Oxotetradecanoyl-CoA_m is out of the hard bounds.
Error: Species concentration Glycerate_c is out of the hard bounds.
long-chain-acyl-CoA dehydrogenase EC:1.3.99.13
Proposed Fatty Acid Transporter (FAT) TCDB:4.C.1.1.5
Error: Species concentration 5beta-Cholestane-3alpha,7alpha,12alpha,26-tetrol_m is out of the hard bounds.
Warning: Species concentration Sarcosine_c is out of the soft bounds.
Warning: Species concentration Methanol_s is out of the soft bounds.
Warning: Species concentration Pyruvate_s is out of the soft bounds.
2-oxoglutarate dehydrogenase E1 component Citrate cycle (TCA cycle) EC:1.2.4.2
Warning: Species concentration Cholesterol-ester-pool_l is out of the soft bounds.
Palmitoyl-CoA:L-carnitine O-palmitoyltransferase Fatty acid metabolism EC:2.3.1.21
Error: Species concentration Pi_p is out of the hard bounds.
Error: Species concentration Malate_c is out of the hard bounds.
Warning: Species concentration Glycerate_m is out of the soft bounds.
Warning: Species concentration prostaglandin-f2beta_c is out of the soft bounds.
Warning: Species concentration dUMP_m is out of the soft bounds.
L-Glutamine:D-fructose-6-phosphate aminotransferase (hexose isomerizing) Glutamate metabolism / Aminosugars metabolism EC:2.6.1.16
(S)-malate:NAD+ oxidoreductase Citrate cycle (TCA cycle) EC:1.1.1.37
Warning: Species concentration PC-VLDL-pool_r is out of the soft bounds.
trans-Hexadec-2-enoyl-CoA reductase Fatty acid elongation in mitochondria EC:1.3.1.38
Warning: Species concentration Collagen_CO8A2_c is out of the soft bounds.
Warning: Species concentration PPi_p is out of the soft bounds.
Warning: Species concentration 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol_r is out of the soft bounds.
Warning: Species concentration (3Z)-Dodecenoyl-CoA_m is out of the soft bounds.
succinyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-succinyltransferase Citrate cycle (TCA cycle) EC:2.3.1.61
L-1-Pyrroline-3-hydroxy-5-carboxylate:NAD+ oxidoreductase Arginine and proline metabolism EC:1.5.1.12
Error: Species concentration 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA_p is out of the hard bounds.
Error: Species concentration trans-4-Hydroxy-L-proline_c is out of the hard bounds.
Collagen alpha-4(IV) chain Protein assembly
Warning: Species concentration SM-pool_b is out of the soft bounds.
Error: Species concentration Acyl-CoA-VLDL-TG3-pool_c is out of the hard bounds.
Warning: Species concentration IMP_c is out of the soft bounds.
Error: Species concentration Collagen_COLQ_c is out of the hard bounds.
Error: Species concentration Linoleate_s is out of the hard bounds.
Warning: Species concentration Maltose_s is out of the soft bounds.
Resistance-Nodulation-Cell Division (RND) TCDB:2.A.60.1.14
L-Aspartate:2-oxoglutarate aminotransferase Glutamate metabolism / Alanine and aspartate metabolism EC:2.6.1.1
L-Serine hydro-lyase (deaminating) Cysteine metabolism EC:4.3.1.17
Error: Species concentration 4-Nitrophenyl-P_s is out of the hard bounds.
Error: Species concentration Collagen_COGA1_c is out of the hard bounds.
Error: Species concentration Sulfate_m is out of the hard bounds.
Error: Species concentration Inositol_s is out of the hard bounds.
Warning: Species concentration gamma-Linolenate_l is out of the soft bounds.
Warning: Species concentration 3-Methylcrotonyl-CoA_m is out of the soft bounds.
ATP:nucleoside-diphosphate phosphatransferase Purine metabolism EC:2.7.4.6
Error: Species concentration prostaglandin-e3_s is out of the hard bounds.
ATP:D-fructose-6-phosphate 1-phosphotransferase EC:2.7.1.11
deoxyuridine:orthophosphate 2-deoxy-D-ribosyltransferase; deoxyuridine:orthophosphate ribosyltransferase Pyrimidine metabolism EC:2.4.2.23
Error: Species concentration Dihydrofolate_c is out of the hard bounds.
Warning: Species concentration beta-Alanine_c is out of the soft bounds.
Warning: Species concentration ADP_m is out of the soft bounds.
Warning: Species concentration Lysine_c is out of the soft bounds.
Error: Species concentration Farnesyl-PP_r is out of the hard bounds.
1,2-Diacyl-sn-glycerol acylhydrolase Glycerolipid metabolism EC:3.1.1.3
D-Glyceraldehyde:NAD+ oxidoreductase Glycerolipid metabolism EC:1.2.1.3
5-methyltetrahydrofolate:NADP+ oxidoreductase One carbon pool by folate / Methane metabolism EC:1.5.1.20
Error: Species concentration Collagen_CO6A3_c is out of the hard bounds.
Acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase Glutamate metabolism / Aminosugars metabolism EC:2.3.1.4
Error: Species concentration dGTP_c is out of the hard bounds.
S-Adenosylmethioninamine:putrescine 3-aminopropyltransferase Urea cycle and metabolism of amino groups / Methionine metabolism EC:2.5.1.16
Warning: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanate_c is out of the soft bounds.
Warning: Species concentration Collagen_COGA1_c is out of the soft bounds.
Warning: Species concentration Collagen_ITA1_c is out of the soft bounds.
Warning: Species concentration 3-Oxooctanoyl-CoA_m is out of the soft bounds.
Warning: Species concentration Xanthurenate_s is out of the soft bounds.
Error: Species concentration Succinate_semialdehyde_m is out of the hard bounds.
Warning: Species concentration 3-Oxostearoyl-ACP_c is out of the soft bounds.
Warning: Species concentration Urate_p is out of the soft bounds.
Concentrative Nucleoside Transporter (CNT) TCDB:2.A.41.2.6
Error: Species concentration S-Glutaryldihydrolipoamide_m is out of the hard bounds.
Error: Species concentration Fe2+_c is out of the hard bounds.
Warning: Species concentration Pyridoxine_s is out of the soft bounds.
Error: Species concentration 3-Oxohexanoyl-CoA_m is out of the hard bounds.
Error: Species concentration H2O2_m is out of the hard bounds.
Error: Species concentration Methylmalonate_c is out of the hard bounds.
(S)-3-Hydroxyhexadecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.211 EC:1.1.1.35
L-Glutamate:ammonia ligase (ADP-forming) Glutamate metabolism / Nitrogen metabolism EC:6.3.1.2
Warning: Species concentration AKG_m is out of the soft bounds.
Error: Species concentration Bilirubin-bisglucuronoside_r is out of the hard bounds.
NADPH:6,7-dihydropteridine oxidoreductase Folate biosynthesis EC:1.5.1.34
Warning: Species concentration PE-VLDL-pool_b is out of the soft bounds.
3-Methoxy-4-hydroxyphenylglycolaldehyde:NADP+ oxidoreductase Tyrosine metabolism EC:1.2.1.5
Warning: Species concentration THF-hexaglutamate_c is out of the soft bounds.
myristoyl-CoA:acetylCoA C-myristoyltransferase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:2.3.1.16
Warning: Species concentration Collagen_CO9A3_c is out of the soft bounds.
Sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase Pentose phosphate pathway EC:2.2.1.1
Warning: Species concentration prostaglandin-b2_c is out of the soft bounds.
Error: Species concentration Stearate_s is out of the hard bounds.
Warning: Species concentration Nicotinate_ribonucleotide_c is out of the soft bounds.
Warning: Species concentration dCDP_c is out of the soft bounds.
Warning: Species concentration Serine_m is out of the soft bounds.
Propanoyl-CoA:acetyl-CoA C-acyltransferase Bile acid biosynthesis EC:2.3.1.16
Warning: Species concentration ApoA1_l is out of the soft bounds.
Warning: Species concentration Lanosterol_r is out of the soft bounds.
Error: Species concentration Putrescine_m is out of the hard bounds.
Warning: Species concentration Dopamine_c is out of the soft bounds.
Orotidine-5'-phosphate:pyrophosphate phosphoribosyltransferase Pyrimidine metabolism EC:2.4.2.10
Resistance-Nodulation-Cell Division (RND) TCDB:2.A.65.1.1
Warning: Species concentration CoA-activated_acetyl_group_p is out of the soft bounds.
Error: Species concentration Tryptophan_l is out of the hard bounds.
Error: Species concentration 1-Acylglycerol-3P-CL-pool_m is out of the hard bounds.
Warning: Species concentration ATP_s is out of the soft bounds.
Warning: Species concentration linoleic-Carnitine_r is out of the soft bounds.
gamma-glutamyltranspeptidase Glutathione metabolism EC:3.4.11.4
Warning: Species concentration Fibrinogen_l is out of the soft bounds.
Warning: Species concentration Methylglyoxal_s is out of the soft bounds.
Warning: Species concentration AKG_c is out of the soft bounds.
Warning: Species concentration Phenylalanine_c is out of the soft bounds.
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane:NAD+ oxidoreductase (B-specific) Bile acid biosynthesis EC:1.1.1.50
Ubiquinol:ferricytochrome-c oxidoreductase Oxidative phosphorylation EC:1.10.2.2
Error: Species concentration prostaglandin-f2beta_s is out of the hard bounds.
Error: Species concentration 2,5-Dihydroxybenzoate_c is out of the hard bounds.
Error: Species concentration Linoleoyl-CoA_c is out of the hard bounds.
(S)-Dihydroorotate amidohydrolase Pyrimidine metabolism EC:3.5.2.3
Warning: Species concentration Isoleucine_m is out of the soft bounds.
Warning: Species concentration Ornithine_m is out of the soft bounds.
Warning: Species concentration prostaglandin-g2_c is out of the soft bounds.
Glutathione:hydrogen-peroxide oxidoreductase Glutathione metabolism EC:1.11.1.9
Hexanoyl-CoA:acetyl-CoA C-acyltransferase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:2.3.1.16
ATP-binding Cassette (ABC) TCDB:3.A.1.201.3
Error: Species concentration dADP_c is out of the hard bounds.
Error: Species concentration Bile-PC-pool_c is out of the hard bounds.
long-chain fatty-acyl-CoA hydrolase EC:3.1.2.2
Warning: Species concentration ApoB100_c is out of the soft bounds.
Error: Species concentration Cholate_b is out of the hard bounds.
Warning: Species concentration NO_c is out of the soft bounds.
Warning: Species concentration Folate_s is out of the soft bounds.
Succinate:CoA ligase (ADP-forming) Citrate cycle (TCA cycle) / Propanoate metabolism EC:6.2.1.5
(R)-2-Methyl-3-oxopropanoyl-CoA 2-epimerase Valine, leucine and isoleucine degradation / Propanoate metabolism EC:5.1.99.1
Warning: Species concentration Threonine_l is out of the soft bounds.
Warning: Species concentration ATP_r is out of the soft bounds.
Error: Species concentration O-Acetylcarnitine_c is out of the hard bounds.
Warning: Species concentration Dihomo-gamma-linolenate_r is out of the soft bounds.
Warning: Species concentration Protoporphyrinogen_IX_m is out of the soft bounds.
Error: Species concentration Glycogenin-G4G7_c is out of the hard bounds.
Warning: Species concentration Histamine_c is out of the soft bounds.
Error: Species concentration Pyruvate_c is out of the hard bounds.
N-Acyl-D-glucosamine 2-epimerase Aminosugars metabolism EC:5.1.3.8
Error: Species concentration dCMP_c is out of the hard bounds.
Error: Species concentration Ornithine_s is out of the hard bounds.
Warning: Species concentration Palmitate_c is out of the soft bounds.
Warning: Species concentration Collagen_CO2A1_c is out of the soft bounds.
Error: Species concentration CDP-diacylglycerol-VLDL-PI-pool_r is out of the hard bounds.
Warning: Species concentration L-erythro-4-Hydroxyglutamate_m is out of the soft bounds.
Error: Species concentration 3-Ureidopropionate_c is out of the hard bounds.
Warning: Species concentration SM-pool_r is out of the soft bounds.
Warning: Species concentration LacCer-pool_s is out of the soft bounds.
acyl-Coenzyme A dehydrogenase family, member 9 Bile acid biosynthesis EC:1.3.3.6
Warning: Species concentration 14-Demethyllanosterol_r is out of the soft bounds.
Mitochondrial Carrier (MC) TCDB:2.A.29.16.1
Warning: Species concentration Carbamoyl-P_m is out of the soft bounds.
Warning: Species concentration PGP-CL-pool_m is out of the soft bounds.
Warning: Species concentration Bile-PC-pool_c is out of the soft bounds.
Warning: Species concentration Glycerol_c is out of the soft bounds.
Error: Species concentration Acetate_m is out of the hard bounds.
Error: Species concentration Acetyl-CoA_c is out of the hard bounds.
Error: Species concentration Glycine_c is out of the hard bounds.
Warning: Species concentration PEP_m is out of the soft bounds.
Error: Species concentration UDP-glucuronate_c is out of the hard bounds.
Error: Species concentration FMN_c is out of the hard bounds.
Collagen alpha-1(XVI) chain Protein assembly
Warning: Species concentration Acetylcholine_b is out of the soft bounds.
Warning: Species concentration dGMP_s is out of the soft bounds.
Error: Species concentration Pyridoxamine-P_c is out of the hard bounds.
Glycerol:NADP+ oxidoreductase Glycerolipid metabolism EC:1.1.1.2 EC:1.1.1.72
Warning: Species concentration Glucono-1,5-lactone-6P_c is out of the soft bounds.
dUTP:uridine 5'-phosphotransferase Pyrimidine metabolism EC:2.7.1.48
Error: Species concentration Valine_l is out of the hard bounds.
Error: Species concentration SAICAR_c is out of the hard bounds.
Error: Species concentration Dihydrothymine_m is out of the hard bounds.
S-Adenosyl-L-methionine:guanidinoacetate N-methyltransferase Glycine, serine and threonine metabolism / Arginine and proline metabolism EC:2.1.1.2
Error: Species concentration Cholesterol_r is out of the hard bounds.
Warning: Species concentration Glucose_c is out of the soft bounds.
Error: Species concentration Chenodeoxycholoyl-CoA_c is out of the hard bounds.
Error: Species concentration (2E)-Octenoyl-CoA_m is out of the hard bounds.
Warning: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanate_p is out of the soft bounds.
Warning: Species concentration Glutaryl-CoA_m is out of the soft bounds.
Mitochondrial Carrier (MC) TCDB:2.A.29.7.2
Warning: Species concentration Dihomo-gamma-linolenate_l is out of the soft bounds.
D-Glucose-6-phosphate ketol-isomerase EC:5.3.1.9
Warning: Species concentration 5beta-Cholestane-3alpha,7alpha,26-triol_m is out of the soft bounds.
Warning: Species concentration UDP-activated-xylose_c is out of the soft bounds.
Warning: Species concentration Palmitolate_r is out of the soft bounds.
Warning: Species concentration prostaglandin-f2alpha_c is out of the soft bounds.
Collagen alpha-1(XXVIII) chain Protein assembly
Error: Species concentration (R)-4-Phosphopantothenoyl-cysteine_c is out of the hard bounds.
Warning: Species concentration Pyridoxal_s is out of the soft bounds.
Collagen alpha-1(XXVII) chain Protein assembly
Collagen alpha-1(XII) chain Protein assembly
Warning: Species concentration Zinc_s is out of the soft bounds.
Error: Species concentration PI-pool_c is out of the hard bounds.
Error: Species concentration CO2_p is out of the hard bounds.
Warning: Species concentration 2-Oxobutyrate_m is out of the soft bounds.
N-Acetyl-D-glucosamine 1-phosphate 1,6-phosphomutase Aminosugars metabolism EC:5.4.2.3
(5-Glutamyl)-peptide:amino-acid 5-glutamyltransferase Arachidonic acid metabolism EC:2.3.2.2
Error: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-24-oxocholestanoyl-CoA_p is out of the hard bounds.
Warning: Species concentration H+(PG)_s is out of the soft bounds.
Error: Species concentration Deamido-NAD_c is out of the hard bounds.
Error: Species concentration Glucosamine_s is out of the hard bounds.
Error: Species concentration Thymidine_c is out of the hard bounds.
Error: Species concentration Pyridoxine-P_c is out of the hard bounds.
Warning: Species concentration HDL_r is out of the soft bounds.
Error: Species concentration HMG-CoA_c is out of the hard bounds.
Error: Species concentration Hypoxanthine_s is out of the hard bounds.
Error: Species concentration PC-VLDL-pool_s is out of the hard bounds.
Error: Species concentration 7alpha-Hydroxy-5beta-cholestan-3-one_c is out of the hard bounds.
Warning: Species concentration H2S_c is out of the soft bounds.
Error: Species concentration Nicotinate_ribonucleotide_c is out of the hard bounds.
Warning: Species concentration Glucosylceramide-pool_s is out of the soft bounds.
CTP:N-acylneuraminate cytidylyltransferase Aminosugars metabolism EC:2.7.7.43
5,6-Dihydrothymine:NADP+ oxidoreductase Pyrimidine metabolism EC:1.3.1.2
Warning: Species concentration leukotriene-f4_s is out of the soft bounds.
Error: Species concentration PPi_s is out of the hard bounds.
Warning: Species concentration Antichymotrypsin_s is out of the soft bounds.
Warning: Species concentration Nicotinamide_D-ribonucleotide_c is out of the soft bounds.
Error: Species concentration L-Fuculose_c is out of the hard bounds.
Error: Species concentration 6-[(1S,2R)-1,2-Dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin_s is out of the hard bounds.
Warning: Species concentration 1,2-Diacylglycerol-VLDL-PI-pool_c is out of the soft bounds.
Warning: Species concentration Serotonin_c is out of the soft bounds.
Error: Species concentration Oxalosuccinate_m is out of the hard bounds.
Warning: Species concentration Glucose-6P_c is out of the soft bounds.
Error: Species concentration Cholesterol-ester-ol_l is out of the hard bounds.
Error: Species concentration glutathionyl-leuc4_s is out of the hard bounds.
Glycerolipid metabolism / Glycerophospholipid metabolism EC:2.3.1.51
Error: Species concentration 3alpha,7alpha,12alpha-Trihydroxycoprostane_m is out of the hard bounds.
Warning: Species concentration Guanidinoacetate_c is out of the soft bounds.
Error: Species concentration Glutamyl-5P_m is out of the hard bounds.
Error: Species concentration Provitamin_D3_r is out of the hard bounds.
Warning: Species concentration 7alpha-Hydroxy-5beta-cholestan-3-one_c is out of the soft bounds.
Warning: Species concentration 3-Hydroxypropionyl-CoA_m is out of the soft bounds.
Warning: Species concentration gamma-Linolenoyl-CoA_r is out of the soft bounds.
Error: Species concentration Protoporphyrin_m is out of the hard bounds.
Error: Species concentration CoA-activated_acetyl_group_c is out of the hard bounds.
Error: Species concentration GAP_c is out of the hard bounds.
Error: Species concentration Dephospho-CoA_m is out of the hard bounds.
(S)-3-Hydroxydodecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.35 EC:1.1.1.211
hypotaurine:NAD+ oxidoreductase Taurine and hypotaurine metabolism EC:1.8.1.3
Error: Species concentration GDP-4-dehydro-6-deoxy-D-mannose_c is out of the hard bounds.
ATP:thymidine 5'-phosphotransferase Pyrimidine metabolism EC:2.7.1.21
Glycoside-Pentoside-Hexuronide (GPH):Cation Symporter TCDB:2.A.28.1.1
Warning: Species concentration O-Acetylcarnitine_c is out of the soft bounds.
Warning: Species concentration Homocarnosine_c is out of the soft bounds.
Warning: Species concentration CDP_s is out of the soft bounds.
Warning: Species concentration Stearate_c is out of the soft bounds.
Error: Species concentration Malonyl-Carnitin_p is out of the hard bounds.
delta8,24-Cholestadien-3beta-ol delta7-delta8-isomerase Biosynthesis of steroids EC:5.3.3.5
Warning: Species concentration 3-Oxopropanoate_m is out of the soft bounds.
Drug/Metabolite Transporter (DMT) TCDB:2.A.7.12.7
Warning: Species concentration Inositol_r is out of the soft bounds.
AMP aminohydrolase Purine metabolism EC:3.5.4.6
Warning: Species concentration Glutamate_m is out of the soft bounds.
ATP:L-glutamate 5-phosphotransferase Urea cycle and metabolism of amino groups EC:2.7.2.11
Error: Species concentration Gentisate_aldehyde_c is out of the hard bounds.
Warning: Species concentration Arachidonyl-CoA_c is out of the soft bounds.
Warning: Species concentration UDP-activated-N-acetyl-D-galactosamine_c is out of the soft bounds.
Error: Species concentration Alanine_m is out of the hard bounds.
L-Glutamate:NAD+ oxidoreductase (deaminating) Glutamate metabolism EC:1.4.1.3 EC:1.4.1.2
Warning: Species concentration PS-VLDL-pool_c is out of the soft bounds.
Warning: Species concentration Spermidine_s is out of the soft bounds.
Warning: Species concentration UDP_r is out of the soft bounds.
Error: Species concentration Chloride_c is out of the hard bounds.
Warning: Species concentration Collagen_EMID2_c is out of the soft bounds.
Warning: Species concentration Butyryl-ACP_c is out of the soft bounds.
Error: Species concentration 5-Formyl-THF_m is out of the hard bounds.
Error: Species concentration Methacrylyl-CoA_m is out of the hard bounds.
Warning: Species concentration dGTP_s is out of the soft bounds.
Warning: Species concentration PEP_c is out of the soft bounds.
Mitochondrial Carrier (MC) TCDB:2.A.29.2.7
CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase Glycerophospholipid metabolism EC:2.7.8.1
Warning: Species concentration 4-Aminobutyrate_m is out of the soft bounds.
Deoxyinosine:orthophosphate ribosyltransferase Purine metabolism EC:2.4.2.1 EC:2.4.2.4
Warning: Species concentration Histidine_s is out of the soft bounds.
Error: Species concentration (3Z)-Dodecenoyl-CoA_m is out of the hard bounds.
Error: Species concentration Xanthosine_c is out of the hard bounds.
Warning: Species concentration sulfochenodeoxycholate_s is out of the soft bounds.
Error: Species concentration Ribitol_c is out of the hard bounds.
Error: Species concentration Collagen_COPA1_c is out of the hard bounds.
Warning: Species concentration trans,cis-octadeca-2,9-dienoyl-CoA_m is out of the soft bounds.
CDPdiacylglycerol:myo-inositol 3-phosphatidyltransferase Glycerophospholipid metabolism / Phosphatidylinositol signaling system EC:2.7.8.11
Warning: Species concentration Formate_s is out of the soft bounds.
Error: Species concentration IMP_c is out of the hard bounds.
Concentrative Nucleoside Transporter (CNT) TCDB:2.A.41.2.4
Warning: Species concentration 3-Ketolactose_s is out of the soft bounds.
Warning: Species concentration Tiglyl-CoA_m is out of the soft bounds.
Warning: Species concentration HDL_s is out of the soft bounds.
Error: Species concentration Palmitate_p is out of the hard bounds.
Error: Species concentration Acyl-CoA-VLDL-PE-pool_c is out of the hard bounds.
Nalpha-(beta-alanyl)-L-histidine hydrolase Alanine and aspartate metabolism / Histidine metabolism / beta-Alanine metabolism EC:3.4.13.3
S-(hydroxymethyl)glutathione dehydrogenase Methane metabolism EC:1.1.1.284
xanthine:NAD+ oxidoreductase Purine metabolism EC:1.17.1.4
Warning: Species concentration Sulfate_s is out of the soft bounds.
Error: Species concentration Isobutyryl-CoA_m is out of the hard bounds.
ATP:dephospho-CoA 3'-phosphotransferase Pantothenate and CoA biosynthesis EC:2.7.1.24
Error: Species concentration 1,3DPG_c is out of the hard bounds.
Warning: Species concentration Inositol_c is out of the soft bounds.
Error: Species concentration prostaglandin-h2_s is out of the hard bounds.
Error: Species concentration PPi_r is out of the hard bounds.
Error: Species concentration Collagen_CO6A1_c is out of the hard bounds.
Warning: Species concentration leukotriene-b4_s is out of the soft bounds.
Warning: Species concentration Leucine_s is out of the soft bounds.
Error: Species concentration dTTP_s is out of the hard bounds.
Error: Species concentration Collagen_COLA1_c is out of the hard bounds.
Error: Species concentration Collagen_COBA1_c is out of the hard bounds.
Warning: Species concentration 2-Oxoglutaramate_m is out of the soft bounds.
5-Aminolevulinate hydro-lyase(adding 5-aminolevulinate and cyclizing) Porphyrin and chlorophyll metabolism EC:4.2.1.24
D-Glyceraldehyde-3-phosphate ketol-isomerase Glycolysis / Gluconeogenesis EC:5.3.1.1
Warning: Species concentration 1,2-Diacylglycerol-VLDL-TG-pool_c is out of the soft bounds.
6-Phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating) Pentose phosphate pathway EC:1.1.1.44
Warning: Species concentration Stearoyl-CoA_c is out of the soft bounds.
Error: Species concentration Orotate_s is out of the hard bounds.
Warning: Species concentration Pyridoxamine_c is out of the soft bounds.
Error: Species concentration ADP_m is out of the hard bounds.
Warning: Species concentration Ethanolamine_c is out of the soft bounds.
Warning: Species concentration CMP-N-acetylneuraminate_n is out of the soft bounds.
UDP-D-glucuronate carboxy-lyase Starch and sucrose metabolism / Nucleotide sugars metabolism EC:4.1.1.35
Warning: Species concentration Collagen_COPA1_c is out of the soft bounds.
Error: Species concentration 3-oxomyrist-7-enoyl-CoA_m is out of the hard bounds.
Error: Species concentration Serine_l is out of the hard bounds.
Warning: Species concentration Acetoacetate_s is out of the soft bounds.
Formate:tetrahydrofolate ligase (ADP-forming) Glyoxylate and dicarboxylate metabolism / One carbon pool by folate EC:6.3.4.3
Error: Species concentration Guanine_s is out of the hard bounds.
5,10-methylenetetrahydrofolate:NAD+ oxidoreductase One carbon pool by folate EC:1.5.1.15
3-Hydroxy-2-methylpropanoyl-CoA hydrolase EC:3.1.2.4
Warning: Species concentration Butyrate_s is out of the soft bounds.
Warning: Species concentration D-Xylulose-5P_c is out of the soft bounds.
Warning: Species concentration (S)-3-Hydroxy-2-methylbutyryl-CoA_m is out of the soft bounds.
FAD nucleotidohydrolase Riboflavin metabolism EC:3.6.1.9 EC:3.6.1.18
Error: Species concentration LTD4_s is out of the hard bounds.
Warning: Species concentration (R)-Mevalonate_c is out of the soft bounds.
Warning: Species concentration Phosphodimethylethanolamine_c is out of the soft bounds.
Warning: Species concentration trans,cis-hexadeca-2,9-dienoyl-CoA_m is out of the soft bounds.
S-Adenosylmethioninamine:putrescine 3-aminopropyltransferase Urea cycle and metabolism of amino groups / beta-Alanine metabolism EC:2.5.1.22
Warning: Species concentration dCTP_c is out of the soft bounds.
Warning: Species concentration CDP-diacylglycerol-VLDL-PI-pool_r is out of the soft bounds.
Error: Species concentration Acrylyl-CoA_m is out of the hard bounds.
Error: Species concentration Ribose-5P_r is out of the hard bounds.
(S)-3-methyl-2-oxopentanoate:NAD+ 2-oxidoreductase (CoA-methylbutanoylating) Valine, leucine and isoleucine degradation EC:1.2.1.25
Warning: Species concentration 1,2-Diacylglycerol-VLDL-PS-pool_c is out of the soft bounds.
Warning: Species concentration Collagen_COIA1_c is out of the soft bounds.
Warning: Species concentration CoproporphyrinogenI_s is out of the soft bounds.
Warning: Species concentration 3-Oxooctanoyl-ACP_c is out of the soft bounds.
Warning: Species concentration Agmatine_m is out of the soft bounds.
Error: Species concentration 4-Imidazolone-5-propanoate_c is out of the hard bounds.
Warning: Species concentration HCO3-_c is out of the soft bounds.
ATP pyrophosphate-lyase (cyclizing) Purine metabolism EC:4.6.1.1
Error: Species concentration L-Palmitoylcarnitine_c is out of the hard bounds.
Error: Species concentration N-Acetylglucosamine_r is out of the hard bounds.
Warning: Species concentration H2O2_p is out of the soft bounds.
Error: Species concentration Phenylalanine_l is out of the hard bounds.
Warning: Species concentration Taurochenodeoxycholate_c is out of the soft bounds.
Warning: Species concentration Palmitoyl-CoA_c is out of the soft bounds.
Reduced Folate Carrier (RFC) TCDB:2.A.48.2.1
Phosphatidylcholine cholinephosphohydrolase Glycine, serine and threonine metabolism / Glycerophospholipid metabolism EC:3.1.4.4
Error: Species concentration Arginine_l is out of the hard bounds.
Warning: Species concentration Putrescine_s is out of the soft bounds.
Warning: Species concentration Prothrombin_c is out of the soft bounds.
Error: Species concentration CoA-activated_acetyl_group_p is out of the hard bounds.
ATP:nucleoside-diphosphate phosphatransferase Pyrimidine metabolism EC:2.7.4.6
Error: Species concentration ATP_s is out of the hard bounds.
Warning: Species concentration Malonyl-ACP_c is out of the soft bounds.
Error: Species concentration Methylglyoxal_s is out of the hard bounds.
Error: Species concentration Collagen_CO7A1_c is out of the hard bounds.
Cytidine-5'-monophosphate phosphohydrolase Pyrimidine metabolism EC:3.1.3.5
Error: Species concentration Collagen_COSA1_c is out of the hard bounds.
Error: Species concentration Bilirubin-monoglucuronoside_s is out of the hard bounds.
Error: Species concentration Decanoyl-CoA_p is out of the hard bounds.
Warning: Species concentration Histidine_m is out of the soft bounds.
Warning: Species concentration UDP-N-acetyl-D-galactosamine_c is out of the soft bounds.
Error: Species concentration dUMP_c is out of the hard bounds.
Warning: Species concentration UDP-glucuronate_c is out of the soft bounds.
Acetaldehyde:NADP+ oxidoreductase Glycolysis / Gluconeogenesis / Pyruvate metabolism EC:1.2.1.5
Error: Species concentration 10-Formyl-THF_c is out of the hard bounds.
Warning: Species concentration Proton-gradient_m is out of the soft bounds.
Warning: Species concentration Nicotinamide_c is out of the soft bounds.
Error: Species concentration N-Methylethanolamine-P_c is out of the hard bounds.
Error: Species concentration Ubiquinol_m is out of the hard bounds.
Warning: Species concentration O-Acetylcarnitine_r is out of the soft bounds.
Error: Species concentration prostaglandin-f1alpha_s is out of the hard bounds.
Warning: Species concentration Collagen_CO5A3_c is out of the soft bounds.
Error: Species concentration CL-pool_m is out of the hard bounds.
Warning: Species concentration 2,5-Diamino-6-(5-triphosphoryl-3,4-trihydroxy-2-oxopentyl)-_amino-4-oxopyrimidine_c is out of the soft bounds.
Error: Species concentration L-Palmitoylcarnitine_p is out of the hard bounds.
Error: Species concentration Aspartate_m is out of the hard bounds.
Error: Species concentration PPi_n is out of the hard bounds.
Warning: Species concentration Glucuronate_c is out of the soft bounds.
Warning: Species concentration 1-Acylglycerol-VLDL-SM-pool_c is out of the soft bounds.
Warning: Species concentration Glycerone_s is out of the soft bounds.
Warning: Species concentration Dihomo-gamma-linolenoyl-CoA_c is out of the soft bounds.
Error: Species concentration L-erythro-4-Hydroxyglutamate_m is out of the hard bounds.
Chenodeoxycholate:CoA ligase (AMP-forming) Bile acid biosynthesis EC:6.2.1.7
Warning: Species concentration Tagatose-1,6PP_c is out of the soft bounds.
Error: Species concentration SM-pool_r is out of the hard bounds.
Error: Species concentration 14-Demethyllanosterol_r is out of the hard bounds.
N-Carbamoyl-beta-alanine amidohydrolase Pyrimidine metabolism / beta-Alanine metabolism / Pantothenate and CoA biosynthesis EC:3.5.1.6
Error: Species concentration PGP-CL-pool_m is out of the hard bounds.
Error: Species concentration NADPH_c is out of the hard bounds.
Error: Species concentration ApoTransferin_c is out of the hard bounds.
Warning: Species concentration UDP-glucose_c is out of the soft bounds.
Error: Species concentration Glutamine_s is out of the hard bounds.
Hoppe2012 - Predicting changes in metabolic function using transcript profiles Measuring metabolite concentrations, reaction fluxes, and enzyme activities on large scale are tricky tasks in the study of cellular metabolism. Here, a method that predicts activity changes of metabolic functions based on relative transcript profiles, has been presented. It provides a ranked list of most regulated functions. The method has been applied to TGF-beta treatment of hepatocyte cultures. This model is described in the article: ModeScore: A Method to Infer Changed Activity of Metabolic Function from Transcript Profiles Andreas Hoppe and Hermann-Georg Holzhütter German Conference on Bioinformatics 2012; Publ.13.09.2012 Abstract: Genome-wide transcript profiles are often the only available quantitative data for a particular perturbation of a cellular system and their interpretation with respect to the metabolism is a major challenge in systems biology, especially beyond on/off distinction of genes. We present a method that predicts activity changes of metabolic functions by scoring reference flux distributions based on relative transcript profiles, providing a ranked list of most regulated functions. Then, for each metabolic function, the involved genes are ranked upon how much they represent a specific regulation pattern. Compared with the naïve pathway-based approach, the reference modes can be chosen freely, and they represent full metabolic functions, thus, directly provide testable hypotheses for the metabolic study. In conclusion, the novel method provides promising functions for subsequent experimental elucidation together with outstanding associated genes, solely based on transcript profiles. This model is hosted on BioModels Database and identified by: MODEL1208060000 . To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. PMID: 20587024 . To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to [CC0 Public Domain Dedication>http://creativecommons.org/publicdomain/zero/1.0/] for more information.
Warning: Species concentration Acetyl-CoA_r is out of the soft bounds.
Warning: Species concentration 3-Hydroxyisobutyryl-CoA_m is out of the soft bounds.
Warning: Species concentration 3-Sulfinoalanine_c is out of the soft bounds.
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 TCDB:2.A.23.2.1 TCDB:2.A.23.2.2 TCDB:2.A.23.2.3
Error: Species concentration Inositol-1P_c is out of the hard bounds.
Mitochondrial Carrier (MC) TCDB:2.A.29.14.3
Error: Species concentration GTP_c is out of the hard bounds.
Error: Species concentration Bilirubin-bisglucuronoside_s is out of the hard bounds.
Error: Species concentration GM4-pool_s is out of the hard bounds.
Warning: Species concentration Sulfate_m is out of the soft bounds.
Error: Species concentration Collagen_CO4A4_c is out of the hard bounds.
ATP pyrophosphohydrolase Purine metabolism EC:3.6.1.5
Butyryl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) Fatty acid biosynthesis EC:2.1.3.85
Warning: Species concentration Lysine_s is out of the soft bounds.
Error: Species concentration Triacylglycerol-VLDL-pool_r is out of the hard bounds.
Warning: Species concentration OAA_c is out of the soft bounds.
Error: Species concentration Methanol_c is out of the hard bounds.
ATP:pyridoxal 5'-phosphotransferase Vitamin B6 metabolism EC:2.7.1.35
Error: Species concentration Lactose-6P_s is out of the hard bounds.
Acetyl adenylate:CoA ligase (AMP-forming) Pyruvate metabolism EC:6.2.1.1
Warning: Species concentration Arginine_m is out of the soft bounds.
Warning: Species concentration 5-Hydroxyindoleacetate_c is out of the soft bounds.
Warning: Species concentration 3alpha,7alpha,12alpha-Trihydroxycoprostane_m is out of the soft bounds.
ATP:(R)-mevalonate 5-phosphotransferase Biosynthesis of steroids EC:2.7.1.36
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase Protein assembly
Error: Species concentration Glycocholate_b is out of the hard bounds.
Warning: Species concentration Carbonate_c is out of the soft bounds.
Warning: Species concentration sulfochenodeoxycholate_c is out of the soft bounds.
Warning: Species concentration Alanine_m is out of the soft bounds.
Error: Species concentration Formylanthranilate_c is out of the hard bounds.
Error: Species concentration 20-hydroxy-arachidonate_s is out of the hard bounds.
Error: Species concentration Na+_c is out of the hard bounds.
Citrate oxaloacetate-lyase ((pro-3S)-CH2COO- -->acetate) Citrate cycle (TCA cycle) EC:4.1.3.6
ATP:3-phospho-D-glycerate 1-phosphotransferase Glycolysis / Gluconeogenesis EC:2.7.2.3
2-Aminomuconate semialdehyde:NAD+ 6-oxidoreductase Tryptophan metabolism EC:1.2.1.32
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
Error: Species concentration Phenylalanine_m is out of the hard bounds.
Warning: Species concentration H2O_s is out of the soft bounds.
Error: Species concentration 3-Oxododecanoyl-CoA_p is out of the hard bounds.
Error: Species concentration Fatty-acid-VLDL-PE-pool_c is out of the hard bounds.
Lauroyl-CoA:acetyl-CoA C-acyltransferase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:2.3.1.16
Error: Species concentration H+(PG)_s is out of the hard bounds.
Error: Species concentration VLDL_l is out of the hard bounds.
Warning: Species concentration Sphinganine_c is out of the soft bounds.
D-Ribose-5-phosphate ketol-isomerase Pentose phosphate pathway EC:5.3.1.6
3-Sulfino-L-alanine carboxy-lyase Taurine and hypotaurine metabolism EC:4.1.1.29
Warning: Species concentration 1-Pyrroline-5-carboxylate_c is out of the soft bounds.
Warning: Species concentration 6-Lactoyl-5,6,7,8-tetrahydropterin_c is out of the soft bounds.
Error: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA_p is out of the hard bounds.
Warning: Species concentration Thymine_m is out of the soft bounds.
Warning: Species concentration Aspartate_s is out of the soft bounds.
Error: Species concentration (2E)-Hexenoyl-ACP_c is out of the hard bounds.
Warning: Species concentration prostaglandin-b1_c is out of the soft bounds.
Error: Species concentration Citrate_c is out of the hard bounds.
dTTP nucleotidohydrolase Pyrimidine metabolism EC:3.6.1.39
Warning: Species concentration Geranyl-PP_p is out of the soft bounds.
Phosphatidylcholine 2-acylhydrolase Glycerophospholipid metabolism EC:3.1.1.4
GDP:D-mannose-1-phosphate guanylyltransferase Fructose and mannose metabolism EC:2.7.7.22
Warning: Species concentration Hexadecanoyl-ACP_c is out of the soft bounds.
Warning: Species concentration Cytidine_c is out of the soft bounds.
Warning: Species concentration mitoOxidizedThioredoxin_m is out of the soft bounds.
Warning: Species concentration Fatty-acid-VLDL-PC-pool_c is out of the soft bounds.
Warning: Species concentration Fructose-1,6PP_c is out of the soft bounds.
Warning: Species concentration Creatine_c is out of the soft bounds.
Tetrahydrobiopterin:NADP+ oxidoreductase Folate biosynthesis EC:1.1.1.153
Error: Species concentration Cholesterol-ester-pool_l is out of the hard bounds.
Error: Species concentration prostaglandin-f2beta_c is out of the hard bounds.
Error: Species concentration Serotonin_c is out of the hard bounds.
Error: Species concentration Glycerate_m is out of the hard bounds.
glycine N-choloyltransferase EC:2.3.1.65
Sphinganine:NADP+ 3-oxidoreductase Sphingolipid metabolism EC:1.1.1.102
Error: Species concentration Glucose-6P_c is out of the hard bounds.
Warning: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA_p is out of the soft bounds.
alpha-D-Glucose 1-phosphate 1,6-phosphomutase Glycolysis / Gluconeogenesis / Starch and sucrose metabolism EC:5.4.2.2 EC:5.4.2.6
Error: Species concentration NADH_r is out of the hard bounds.
Error: Species concentration Collagen_CO8A2_c is out of the hard bounds.
Warning: Species concentration 3alpha,7alpha,12alpha-Trihydroxycoprostane_c is out of the soft bounds.
Error: Species concentration 5-Hydroxy-L-tryptophan_c is out of the hard bounds.
Error: Species concentration prostaglandin-b1_s is out of the hard bounds.
2-oxoglutarate:[dihydrolipoyllysine-residue succinyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating) EC:1.2.4.2
Warning: Species concentration trans-4-Hydroxy-L-proline_m is out of the soft bounds.
Error: Species concentration Pi_r is out of the hard bounds.
Error: Species concentration leukotriene-b4_c is out of the hard bounds.
4,5-Dihydro-4-oxo-5-imidazolepropanoate hydro-lyase Histidine metabolism EC:4.2.1.49
beta-D-Galactosyl-1,4-beta-D-glucosylceramide galactohydrolase Sphingolipid metabolism EC:3.2.1.23
Error: Species concentration dUDP_m is out of the hard bounds.
Warning: Species concentration Linoleate_c is out of the soft bounds.
Warning: Species concentration Collagen_COLA1_c is out of the soft bounds.
Error: Species concentration Phosphatidate-VLDL-SM-pool_c is out of the hard bounds.
Collagen alpha-1(XV) chain Protein assembly
Linoleoyl-CoA, hydrogen-donor:oxygen oxidoreductase Polyunsaturated fatty acid biosynthesis EC:1.14.19.3
Warning: Species concentration (2E)-Tetradecenoyl-CoA_m is out of the soft bounds.
Error: Species concentration Collagen_C43BP_c is out of the hard bounds.
Error: Species concentration Fe3+_s is out of the hard bounds.
Warning: Species concentration Thiamin-PP_m is out of the soft bounds.
Error: Species concentration S-glutathionyl-ethacrynic-acid_b is out of the hard bounds.
Citrate oxaloacetate-lyase ((pro-3S)-CH2COO- -> acetyl-CoA) Citrate cycle (TCA cycle) EC:2.3.3.3
Warning: Species concentration prostaglandin-e3_c is out of the soft bounds.
Warning: Species concentration 3-Ureidopropionate_c is out of the soft bounds.
Warning: Species concentration Malonyl-Carnitin_m is out of the soft bounds.
Error: Species concentration gamma-Linolenoyl-CoA_r is out of the hard bounds.
Warning: Species concentration Collagen_CO6A2_c is out of the soft bounds.
2-Oxopropanal:NADP+ oxidoreductase Pyruvate metabolism EC:1.2.1.49
Tetradecanoyl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) Fatty acid biosynthesis EC:2.3.1.85
Error: Species concentration Crotonyl-CoA_m is out of the hard bounds.
Error: Species concentration FADH2_m is out of the hard bounds.
Warning: Species concentration PE-PS-VLDL-pool_c is out of the soft bounds.
solute carrier family 27 (fatty acid transporter), member 5 TCDB:4.C.1.1.5 TCDB:4.C.1.1.8
ATP:AMP phosphotransferase Purine metabolism EC:2.7.4.11
Error: Species concentration Arachidonyl-CoA_c is out of the hard bounds.
Warning: Species concentration Decanoyl-ACP_c is out of the soft bounds.
Warning: Species concentration Uridine_c is out of the soft bounds.
5-Hydroxyindoleacetaldehyde:NAD+ oxidoreductase Tryptophan metabolism EC:1.2.1.3
Error: Species concentration Ferrocytochrome_C_m is out of the hard bounds.
Error: Species concentration Sucrose_s is out of the hard bounds.
Error: Species concentration prostaglandin-d3_c is out of the hard bounds.
Error: Species concentration Collagen_EMID2_c is out of the hard bounds.
Warning: Species concentration 3-Methoxy-4-hydroxyphenylacetaldehyde_m is out of the soft bounds.
Error: Species concentration Squalene_2,3-oxide_r is out of the hard bounds.
Error: Species concentration Urate_s is out of the hard bounds.
Error: Species concentration Oleate_l is out of the hard bounds.
Amino acid transporter ATB0+ Facilitated diffusion
Warning: Species concentration (S)-Hydroxyhexanoyl-CoA_m is out of the soft bounds.
Error: Species concentration Histidine_s is out of the hard bounds.
Error: Species concentration Arachidonyl-CoA_r is out of the hard bounds.
Error: Species concentration Dihydrobiopterin_c is out of the hard bounds.
Warning: Species concentration Sphinganine-1P_c is out of the soft bounds.
Error: Species concentration PE-VLDL-pool_b is out of the hard bounds.
Warning: Species concentration O-Acetylcarnitine_p is out of the soft bounds.
Error: Species concentration Collagen_CO9A3_c is out of the hard bounds.
Error: Species concentration NADH_p is out of the hard bounds.
Error: Species concentration prostaglandin-c1_c is out of the hard bounds.
Error: Species concentration Bilirubin_c is out of the hard bounds.
(S)-Methylmalonate semialdehyde:NAD+ oxidoreductase Valine, leucine and isoleucine degradation EC:1.2.1.3
Cation-Chloride Cotransporter (CCC) TCDB:2.A.30.5.1
Error: Species concentration S-glutathionyl-2-4-dinitrobenzene_c is out of the hard bounds.
ATP:(d)GMP phosphotransferase Purine metabolism EC:2.7.4.8
Cholesterol:NADP+ delta7-oxidoreductase Biosynthesis of steroids EC:1.3.1.21
Error: Species concentration Glycine_l is out of the hard bounds.
Error: Species concentration taurolithocholate_s is out of the hard bounds.
Warning: Species concentration Cysteamine_c is out of the soft bounds.
Error: Species concentration ApoA1_l is out of the hard bounds.
Error: Species concentration Lanosterol_r is out of the hard bounds.
Warning: Species concentration dTTP_c is out of the soft bounds.
glutathione:NAD+ oxidoreductase Glutamate metabolism EC:1.8.1.7
Warning: Species concentration Collagen_COKA1_c is out of the soft bounds.
Error: Species concentration UTP_c is out of the hard bounds.
Error: Species concentration Fatty-acid-VLDL-TG1-pool_c is out of the hard bounds.
Error: Species concentration Pyridoxamine_c is out of the hard bounds.
4-Aminobutyraldehyde:NAD+ oxidoreductase Urea cycle and metabolism of amino groups EC:1.2.1.3
3alpha,7alpha-Dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming) Bile acid biosynthesis EC:6.2.1.7
Error: Species concentration Fibrinogen_l is out of the hard bounds.
Error: Species concentration Phenylalanine_c is out of the hard bounds.
Warning: Species concentration dTMP_s is out of the soft bounds.
ATP:D-ribose-5-phosphate pyrophosphotransferase Pentose phosphate pathway / Purine metabolism EC:2.7.6.1
Warning: Species concentration Linoleoyl-CoA_r is out of the soft bounds.
Warning: Species concentration Nicotinate_c is out of the soft bounds.
Warning: Species concentration O-Butanoylcarnitine_m is out of the soft bounds.
Error: Species concentration Isoleucine_m is out of the hard bounds.
Warning: Species concentration Heme_m is out of the soft bounds.
Error: Species concentration prostaglandin-g2_c is out of the hard bounds.
Warning: Species concentration NADH_p is out of the soft bounds.
Error: Species concentration Pi_s is out of the hard bounds.
Error: Species concentration UDP-galactose_r is out of the hard bounds.
Warning: Species concentration Acyl-CoA-Bile-PC-pool_c is out of the soft bounds.
3-cis-Dodecenoyl-CoA delta3-cis-delta2-trans-isomerase EC:5.3.3.8
1,2-Diacyl-sn-glycerol 3-phosphate phosphohydrolase Glycerolipid metabolism / Glycerophospholipid metabolism EC:3.1.3.4
Dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase Biosynthesis of steroids / Terpenoid biosynthesis EC:2.5.1.1
ATP:CMP phosphotransferase Pyrimidine metabolism EC:2.7.4.14
Warning: Species concentration LTD4_c is out of the soft bounds.
Warning: Species concentration (2E)-Tetradecenoyl-ACP_c is out of the soft bounds.
Warning: Species concentration Cholesterol-ester-arach_r is out of the soft bounds.
Error: Species concentration (R)-Mevalonate_c is out of the hard bounds.
Warning: Species concentration Cholate_c is out of the soft bounds.
collagen, type XIX, alpha 1 Protein assembly
Error: Species concentration Folate_s is out of the hard bounds.
Error: Species concentration Arachidonate_s is out of the hard bounds.
Error: Species concentration trans,cis-hexadeca-2,9-dienoyl-CoA_m is out of the hard bounds.
Error: Species concentration PEP_c is out of the hard bounds.
Error: Species concentration Dihomo-gamma-linolenate_s is out of the hard bounds.
Warning: Species concentration Glycocholate_s is out of the soft bounds.
Warning: Species concentration Sulfite_c is out of the soft bounds.
Error: Species concentration CoproporphyrinogenIII_c is out of the hard bounds.
Nicotinate D-ribonucleoside:orthophosphate ribosyltransferase Nicotinate and nicotinamide metabolism EC:2.4.2.1
Error: Species concentration (R)-3-Hydroxybutanoate_c is out of the hard bounds.
Warning: Species concentration NADPH_m is out of the soft bounds.
(S)-3-Hydroxydodecanoyl-CoA hydro-lyase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:4.2.1.17
Warning: Species concentration (2E)-Hexadecenoyl-CoA_c is out of the soft bounds.
4,4-dimethyl-5a-cholesta-8,24-dien-3b-ol:NADP+ D14-oxidoreductase Biosynthesis of steroids EC:1.3.1.70
L-1-Pyrroline-3-hydroxy-5-carboxylate:NADP+ oxidoreductase Arginine and proline metabolism EC:1.5.1.12
Error: Species concentration 1-Acylglycerol-3P-VLDL-TG1-pool_c is out of the hard bounds.
acetyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-acetyltransferase Glycolysis / Gluconeogenesis / Alanine and aspartate metabolism / Pyruvate metabolism EC:2.3.1.12
Error: Species concentration 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol_r is out of the hard bounds.
Error: Species concentration HMG-CoA_m is out of the hard bounds.
Error: Species concentration H2O2_p is out of the hard bounds.
Warning: Species concentration Nicotinate_D-ribonucleoside_c is out of the soft bounds.
ATP-binding Cassette (ABC) TCDB:3.A.1.208.15
Error: Species concentration Taurochenodeoxycholate_c is out of the hard bounds.
Error: Species concentration Palmitoyl-CoA_c is out of the hard bounds.
Error: Species concentration Carbonate_c is out of the hard bounds.
Error: Species concentration LacCer-pool_s is out of the hard bounds.
Warning: Species concentration NH4+_c is out of the soft bounds.
3-Phospho-D-glycerate:NAD+ 2-oxidoreductase Glycine, serine and threonine metabolism EC:1.1.1.95
Warning: Species concentration GTP_s is out of the soft bounds.
Warning: Species concentration dUTP_c is out of the soft bounds.
Error: Species concentration leukotriene-a4_c is out of the hard bounds.
Error: Species concentration Collagen_CODA1_c is out of the hard bounds.
Error: Species concentration Glycerol_c is out of the hard bounds.
Warning: Species concentration Acetate_s is out of the soft bounds.
Error: Species concentration Collagen_PCOTH_c is out of the hard bounds.
Error: Species concentration HCO3-_c is out of the hard bounds.
Collagen alpha-1(X) chain Protein assembly
Error: Species concentration Choloyl-CoA_p is out of the hard bounds.
Error: Species concentration 2-Amino-3-oxoadipate_m is out of the hard bounds.
Warning: Species concentration Collagen_CORA1_c is out of the soft bounds.
Error: Species concentration CMP_n is out of the hard bounds.
Warning: Species concentration Cystine_c is out of the soft bounds.
Error: Species concentration Glucose-6P_r is out of the hard bounds.
Error: Species concentration NAD+_c is out of the hard bounds.
sphinganine-1-phosphate palmitaldehyde-lyase Sphingolipid metabolism EC:4.1.2.27
Warning: Species concentration CTP_m is out of the soft bounds.
Error: Species concentration Glucono-1,5-lactone-6P_c is out of the hard bounds.
Error: Species concentration cis-Aconitate_c is out of the hard bounds.
Thymidylate 5'-phosphohydrolase Pyrimidine metabolism EC:3.1.3.5 EC:3.1.3.35
Error: Species concentration Saccharopine_m is out of the hard bounds.
Error: Species concentration prostaglandin-i2_s is out of the hard bounds.
Error: Species concentration Isoleucine_l is out of the hard bounds.
Warning: Species concentration AMP_r is out of the soft bounds.
Error: Species concentration Octanoyl-ACP_c is out of the hard bounds.
Isocitrate:NADP+ oxidoreductase (decarboxylating) Citrate cycle (TCA cycle) EC:1.1.1.42
Warning: Species concentration Collagen_FCN2_c is out of the soft bounds.
3-oxoacyl-ACP synthase, mitochondrial Polyunsaturated fatty acid biosynthesis EC:2.3.1.85
Decanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) Fatty acid biosynthesis EC:2.3.1.85
Warning: Species concentration Phosphatidate-Bile-PC-pool_c is out of the soft bounds.
Warning: Species concentration Chenodeoxycholoyl-CoA_r is out of the soft bounds.
Error: Species concentration 2,5-Diamino-6-(5-triphosphoryl-3,4-trihydroxy-2-oxopentyl)-_amino-4-oxopyrimidine_c is out of the hard bounds.
Warning: Species concentration 3-Methyl-2-oxobutyrate_m is out of the soft bounds.
Warning: Species concentration Glycochenodeoxycholate_b is out of the soft bounds.
D-Mannose 6-phosphate 1,6-phosphomutase Fructose and mannose metabolism EC:5.4.2.8
Warning: Species concentration L-Palmitoylcarnitine_m is out of the soft bounds.
Error: Species concentration UDP-N-acetyl-D-galactosamine_c is out of the hard bounds.
Warning: Species concentration Pantetheine_c is out of the soft bounds.
Error: Species concentration Dihomo-gamma-linolenoyl-CoA_c is out of the hard bounds.
Error: Species concentration O2_m is out of the hard bounds.
Error: Species concentration Isoleucine_s is out of the hard bounds.
Error: Species concentration Palmitolate_r is out of the hard bounds.
Warning: Species concentration Serine_c is out of the soft bounds.
Warning: Species concentration L-1-Pyrroline-3-hydroxy-5-carboxylate_m is out of the soft bounds.
Error: Species concentration Pyridoxal_s is out of the hard bounds.
Warning: Species concentration N-Acetyl-D-mannosamine_c is out of the soft bounds.
p-Cumic alcohol:NADP+ oxidoreductase Glycine, serine and threonine metabolism EC:1.2.1.8
Warning: Species concentration NADPH_r is out of the soft bounds.
Error: Species concentration 2-Hydroxybutyrate_c is out of the hard bounds.
Error: Species concentration Zinc_s is out of the hard bounds.
Warning: Species concentration Glutamine_c is out of the soft bounds.
(3R)-3-Hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase Fatty acid biosynthesis EC:2.3.1.85
Warning: Species concentration Isovaleryl-CoA_m is out of the soft bounds.
Warning: Species concentration CO2_m is out of the soft bounds.
Error: Species concentration DHAP_s is out of the hard bounds.
Warning: Species concentration 3-Oxohexanoyl-ACP_c is out of the soft bounds.
Warning: Species concentration S-Succinyldihydrolipoamide_m is out of the soft bounds.
Warning: Species concentration Bilirubin-bisglucuronoside_c is out of the soft bounds.
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane:NADP+ oxidoreductase (B-specific); 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane:NADP+ oxidoreductase Bile acid biosynthesis EC:1.1.1.50
Acetate:CoA ligase (AMP-forming) Pyruvate metabolism EC:6.2.1.1
Error: Species concentration AMP_p is out of the hard bounds.
Error: Species concentration Butyryl-CoA_m is out of the hard bounds.
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1 Protein assembly
Deamido-NAD+:L-glutamine amido-ligase (AMP-forming) Glutamate metabolism / Nicotinate and nicotinamide metabolism EC:6.3.5.1
Warning: Species concentration dATP_m is out of the soft bounds.
Warning: Species concentration Guanosine_m is out of the soft bounds.
Warning: Species concentration Chitin-component_s is out of the soft bounds.
Acetyl-CoA:carbon-dioxide ligase (ADP-forming) Tetracycline biosynthesis / Pyruvate metabolism / Propanoate metabolism EC:6.4.1.2
Error: Species concentration H2S_c is out of the hard bounds.
Error: Species concentration Collagen_CO4A3_c is out of the hard bounds.
Error: Species concentration Homocysteine_c is out of the hard bounds.
(S)-3-Methyl-2-oxopentanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating) EC:1.2.4.4
Warning: Species concentration L-Lactate_s is out of the soft bounds.
Error: Species concentration leukotriene-f4_s is out of the hard bounds.
Error: Species concentration Stearate_r is out of the hard bounds.
Error: Species concentration Bilirubin_r is out of the hard bounds.
Error: Species concentration Antitrypsin_c is out of the hard bounds.
Error: Species concentration Pyruvate_p is out of the hard bounds.
Error: Species concentration UDP-xylose_r is out of the hard bounds.
Error: Species concentration 1,2-Diacylglycerol-VLDL-PI-pool_c is out of the hard bounds.
beta-N-acetylhexosaminidase Aminosugars metabolism EC:3.2.1.52
Error: Species concentration NADPH-redox-potential_p is out of the hard bounds.
Error: Species concentration Collagen_SERPH_c is out of the hard bounds.
Warning: Species concentration Oxalosuccinate_p is out of the soft bounds.
Warning: Species concentration Oxalosuccinate_c is out of the soft bounds.
Warning: Species concentration Cholesterol-ester-ol_r is out of the soft bounds.
myo-Inositol:oxygen oxidoreductase Ascorbate and aldarate metabolism / Inositol phosphate metabolism EC:1.13.99.1
Warning: Species concentration CoproporphyrinogenIII_c is out of the soft bounds.
Warning: Species concentration Vanillylmandelate_m is out of the soft bounds.
Error: Species concentration Phosphodimethylethanolamine_c is out of the hard bounds.
Warning: Species concentration Phenylalanine_l is out of the soft bounds.
Error: Species concentration Acetoacetyl-ACP_c is out of the hard bounds.
Warning: Species concentration Arginine_c is out of the soft bounds.
Warning: Species concentration PRPP_c is out of the soft bounds.
Warning: Species concentration 2-Amino-3-carboxymuconate_semialdehyde_c is out of the soft bounds.
Error: Species concentration Albumin_s is out of the hard bounds.
Error: Species concentration 5-Phosphoribosylamine_c is out of the hard bounds.
(3R)-3-Hydroxypalmitoyl-[acyl-carrier-protein]:NADP+ oxidoreductase Fatty acid biosynthesis EC:2.3.1.85
Error: Species concentration 2-Methylbutyryl-CoA_m is out of the hard bounds.
Error: Species concentration GSSG_m is out of the hard bounds.
Warning: Species concentration 5,10-Methylene-THF_m is out of the soft bounds.
ATP:6-deoxy-L-galactose 1-phosphotransferase Fructose and mannose metabolism EC:2.7.1.52
Error: Species concentration Xylitol_c is out of the hard bounds.
Warning: Species concentration S-glutathionyl-ethacrynic-acid_c is out of the soft bounds.
Error: Species concentration Phosphopantetheine_m is out of the hard bounds.
Error: Species concentration Antichymotrypsin_c is out of the hard bounds.
Error: Species concentration Fructose-1,6PP_c is out of the hard bounds.
Error: Species concentration Sulfate_b is out of the hard bounds.
Warning: Species concentration Alanine_l is out of the soft bounds.
Warning: Species concentration PE-VLDL-pool_c is out of the soft bounds.
(S)-Malate:NADP+ oxidoreductase(oxaloacetate-decarboxylating) Pyruvate metabolism EC:1.1.1.40
UTP:N-acetyl-alpha-D-glucosamine-1-phosphate uridylyltransferase Aminosugars metabolism EC:2.7.7.23
Error: Species concentration 2-Deoxy-D-ribose-5P_c is out of the hard bounds.
Error: Species concentration HCO3-_b is out of the hard bounds.
Warning: Species concentration 2-Oxo-3-methylvalerate_m is out of the soft bounds.
Error: Species concentration ApoB100_c is out of the hard bounds.
Warning: Species concentration L-Fucose-1P_c is out of the soft bounds.
L-Kynurenine hydrolase Tryptophan metabolism EC:3.7.1.3
Error: Species concentration Kynurenine_c is out of the hard bounds.
Warning: Species concentration Lanosterol_p is out of the soft bounds.
L-Tyrosine:2-oxoglutarate aminotransferase Tyrosine metabolism / Phenylalanine, tyrosine and tryptophan biosynthesis EC:2.6.1.5 EC:2.6.1.57
Error: Species concentration Triacylglycerol-VLDL-pool_l is out of the hard bounds.
Error: Species concentration Threonine_l is out of the hard bounds.
Error: Species concentration Glycogenin-G8_c is out of the hard bounds.
Error: Species concentration Sulfite_m is out of the hard bounds.
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase Fatty acid biosynthesis EC:2.3.1.85
Error: Species concentration 3-Ketolactose_s is out of the hard bounds.
Error: Species concentration Plasminogen_c is out of the hard bounds.
Warning: Species concentration AIR_c is out of the soft bounds.
Warning: Species concentration N-Acetylglucosamine-1P_c is out of the soft bounds.
Error: Species concentration (2E)-Tetradecenoyl-CoA_m is out of the hard bounds.
Warning: Species concentration Homogentisate_c is out of the soft bounds.
Error: Species concentration prostaglandin-b2_s is out of the hard bounds.
ATP:(R)-glycerate 3-phosphotransferase Glycine, serine and threonine metabolism EC:2.7.1.31
Error: Species concentration ATP-energy_c is out of the hard bounds.
Warning: Species concentration prostaglandin-h2_c is out of the soft bounds.
Warning: Species concentration Collagen_COAA1_c is out of the soft bounds.
Glycerol-ester acylhydrolase Glycerolipid metabolism EC:3.1.1.23
Error: Species concentration (R)-3-Hydroxyoctanoyl-ACP_c is out of the hard bounds.
Error: Species concentration Glucosylceramide-pool_c is out of the hard bounds.
ATP:pantetheine-4'-phosphate adenylyltransferase Pantothenate and CoA biosynthesis EC:2.7.7.3
Warning: Species concentration S-glutathionyl-2-4-dinitrobenzene_s is out of the soft bounds.
ATP-binding Cassette (ABC) TCDB:3.A.1.203.3
Error: Species concentration dATP_m is out of the hard bounds.
Warning: Species concentration 3-Ureidoisobutyrate_c is out of the soft bounds.
Phenylacetaldehyde:NAD+ oxidoreductase Phenylalanine metabolism / Styrene degradation EC:1.2.1.5 EC:1.2.1.39
Error: Species concentration Acetoacetate_s is out of the hard bounds.
Decanoyl-CoA:acetyl-CoA C-acyltransferase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:2.3.1.16
4-aminobutanal:NAD+ 1-oxidoreductase; 4-aminobutyraldehyde:NAD+ oxidoreductase Urea cycle and metabolism of amino groups / beta-Alanine metabolism EC:1.2.1.3 EC:1.2.1.19
(S)-Hydroxydecanoyl-CoA hydro-lyase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:4.2.1.17
Warning: Species concentration Methylthioribose-1P_c is out of the soft bounds.
Warning: Species concentration HMG-CoA_p is out of the soft bounds.
Error: Species concentration Urocanate_c is out of the hard bounds.
N6-(L-1,3-Dicarboxypropyl)-L-lysine:NADP+ oxidoreductase Lysine biosynthesis / Lysine degradation EC:1.5.1.10
Warning: Species concentration Urea_m is out of the soft bounds.
Warning: Species concentration prostaglandin-d2_s is out of the soft bounds.
Warning: Species concentration prostaglandin-a1_s is out of the soft bounds.
Warning: Species concentration L-Glutamate_5-semialdehyde_m is out of the soft bounds.
Warning: Species concentration Cysteine_m is out of the soft bounds.
Warning: Species concentration 5-Phosphoribosylformylglycinamidine_c is out of the soft bounds.
Error: Species concentration SM-pool_l is out of the hard bounds.
Error: Species concentration Antitrypsin_s is out of the hard bounds.
Error: Species concentration 1-Acylglycerol-VLDL-PI-pool_c is out of the hard bounds.
Error: Species concentration CDP-diacylglycerol-VLDL-PI-pool_l is out of the hard bounds.
Warning: Species concentration Dihydrothymine_c is out of the soft bounds.
Error: Species concentration Collagen_ITA1_c is out of the hard bounds.
Error: Species concentration Mannose_c is out of the hard bounds.
Warning: Species concentration Glycerol_m is out of the soft bounds.
Error: Species concentration Collagen_COIA1_c is out of the hard bounds.
Error: Species concentration 3-Oxooctanoyl-ACP_c is out of the hard bounds.
UTP:ammonia ligase(ADP-forming) Pyrimidine metabolism EC:6.3.4.2
Warning: Species concentration Linoleate_l is out of the soft bounds.
Warning: Species concentration FADH2_c is out of the soft bounds.
Warning: Species concentration 6-Pyruvoyltetrahydropterin_c is out of the soft bounds.
Warning: Species concentration 7alpha-Hydroxycholesterol_r is out of the soft bounds.
Error: Species concentration HCO3-_m is out of the hard bounds.
5-Formiminotetrahydrofolate ammonia-lyase (cyclizing) One carbon pool by folate EC:4.3.1.4
guanosine:orthophosphate ribosyltransferase Purine metabolism EC:2.4.2.15 EC:2.4.2.1
Succinate-semialdehyde:NAD+ oxidoreductase Glutamate metabolism / Tyrosine metabolism / Butanoate metabolism EC:1.2.1.24 EC:1.2.1.16
Warning: Species concentration GDP_s is out of the soft bounds.
Propanoate:CoA ligase (AMP-forming) EC:6.2.1.17
Error: Species concentration Linolenate_l is out of the hard bounds.
Error: Species concentration Cholesterol-ester-lin_r is out of the hard bounds.
Mitochondrial Carrier (MC) TCDB:2.A.29.8.3
Warning: Species concentration Desmosterol_r is out of the soft bounds.
AMP:pyrophosphate phosphoribosyltransferase Purine metabolism EC:2.4.2.7
Warning: Species concentration Phenylalanine_s is out of the soft bounds.
Warning: Species concentration Xanthurenate_c is out of the soft bounds.
solute carrier family 22 (organic cation/carnitine transporter), member 5 TCDB:2.A.1.19.1 TCDB:2.A.1.19.6 TCDB:2.A.1.19.3
Lactose galactohydrolase EC:3.2.1.23 EC:3.2.1.108
Warning: Species concentration Arginine_s is out of the soft bounds.
Error: Species concentration Prothrombin_c is out of the hard bounds.
L-Fucose ketol-isomerase Fructose and mannose metabolism EC:5.3.1.25
Warning: Species concentration Guanine_s is out of the soft bounds.
Mitochondrial Carrier (MC) TCDB:2.A.29.20.1
Warning: Species concentration Collagen_CO6A6_c is out of the soft bounds.
Warning: Species concentration 1-Acylglycerol-VLDL-PE-pool_c is out of the soft bounds.
Error: Species concentration 2-Oxobutyrate_m is out of the hard bounds.
Error: Species concentration Na+_s is out of the hard bounds.
Warning: Species concentration UTP_s is out of the soft bounds.
Error: Species concentration glycoursodeoxycholate_s is out of the hard bounds.
Error: Species concentration Heme_m is out of the hard bounds.
Warning: Species concentration (2E)-Decenoyl-CoA_m is out of the soft bounds.
Error: Species concentration Pyridoxal-P_c is out of the hard bounds.
Warning: Species concentration Spermine_c is out of the soft bounds.
Warning: Species concentration GSH_m is out of the soft bounds.
Warning: Species concentration ursodeoxycholate_s is out of the soft bounds.
Warning: Species concentration Acetoacetyl-CoA_c is out of the soft bounds.
Warning: Species concentration Fatty-acid-VLDL-PE-pool_c is out of the soft bounds.
Warning: Species concentration Protein_lysine_c is out of the soft bounds.
Error: Species concentration Carbamoyl-P_c is out of the hard bounds.
Warning: Species concentration Hypoxanthine_c is out of the soft bounds.
Dihydrofolate:NADP+ oxidoreductase One carbon pool by folate / Folate biosynthesis EC:1.5.1.3
Error: Species concentration Nicotinamide_c is out of the hard bounds.
Error: Species concentration LDL_s is out of the hard bounds.
Warning: Species concentration Histamine_s is out of the soft bounds.
Warning: Species concentration GAR_c is out of the soft bounds.
Error: Species concentration Nicotinate_c is out of the hard bounds.
Aldehyde:NADP+ oxidoreductase Phenylalanine metabolism EC:1.2.1.5
Error: Species concentration NADPH_m is out of the hard bounds.
Geranyl-diphosphate:isopentenyl-diphosphate geranyltrans-transferase Biosynthesis of steroids / Terpenoid biosynthesis EC:2.5.1.10
solute carrier family 13 (sodium-dependent citrate transporter), member 5 TCDB:2.A.47.1.9 TCDB:2.A.47.1.4
Warning: Species concentration GSH_c is out of the soft bounds.
Warning: Species concentration PPi_c is out of the soft bounds.
Error: Species concentration Triacylglycerol-VLDL-pool_c is out of the hard bounds.
Error: Species concentration Nicotinate_D-ribonucleoside_c is out of the hard bounds.
Error: Species concentration Glycerone_s is out of the hard bounds.
Warning: Species concentration Glycocholate_c is out of the soft bounds.
Error: Species concentration 2-Aminomuconate_semialdehyde_c is out of the hard bounds.
GTP pyrophosphate-lyase (cyclizing) Purine metabolism EC:4.6.1.2
Error: Species concentration dUTP_c is out of the hard bounds.
Error: Species concentration Creatine_s is out of the hard bounds.
trans-4-Hydroxy-L-proline:NAD+ 5-oxidoreductase Arginine and proline metabolism EC:1.5.1.2
Collagen alpha-2(IX) chain Protein assembly
Pyrophosphate phosphohydrolase EC:3.6.1.1
Warning: Species concentration Collagen_LPP3_c is out of the soft bounds.
Warning: Species concentration ApoTransferin_s is out of the soft bounds.
Error: Species concentration Glucose_r is out of the hard bounds.
Warning: Species concentration Xanthine_c is out of the soft bounds.
Warning: Species concentration 7alpha,12alpha-Dihydroxycholest-4-en-3-one_r is out of the soft bounds.
Warning: Species concentration Pi_p is out of the soft bounds.
Warning: Species concentration Deoxyinosine_s is out of the soft bounds.
Warning: Species concentration N-Formimino-L-glutamate_c is out of the soft bounds.
Warning: Species concentration UDP-N-acetylglucosamine_c is out of the soft bounds.
Error: Species concentration (R)-3-Hydroxybutanoyl-ACP_c is out of the hard bounds.
Warning: Species concentration NAD+_r is out of the soft bounds.
Warning: Species concentration Collagen_CO4A5_c is out of the soft bounds.
Warning: Species concentration Tetrahydrobiopterin_c is out of the soft bounds.
(R)-4'-Phosphopantothenate:L-cysteine ligase EC:6.3.2.5
Error: Species concentration Lysine_m is out of the hard bounds.
Error: Species concentration Ribitol_s is out of the hard bounds.
Error: Species concentration 5,6-Dihydrouracil_c is out of the hard bounds.
Warning: Species concentration Acyl-CoA-VLDL-TG3-pool_c is out of the soft bounds.
(R)-3-Amino-2-methylpropanoate:2-oxoglutarate aminotransferase EC:2.6.1.22
Error: Species concentration Uridine_s is out of the hard bounds.
UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase Galactose metabolism / Nucleotide sugars metabolism EC:2.7.7.12
5,6-Dihydrouracil:NADP+ oxidoreductase Pyrimidine metabolism EC:1.3.1.2
Error: Species concentration OAA_c is out of the hard bounds.
Warning: Species concentration Cys-Gly_c is out of the soft bounds.
Warning: Species concentration Na-gradient_c is out of the soft bounds.
Warning: Species concentration Farnesyl-PP_p is out of the soft bounds.
Warning: Species concentration UTP_c is out of the soft bounds.
Error: Species concentration AMP_r is out of the hard bounds.
Error: Species concentration Methionine_l is out of the hard bounds.
Warning: Species concentration 3-Hydroxy-L-kynurenine_c is out of the soft bounds.
Warning: Species concentration GMP_s is out of the soft bounds.
Error: Species concentration Adenosine_m is out of the hard bounds.
Error: Species concentration Collagen_FCN2_c is out of the hard bounds.
Error: Species concentration 7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one_c is out of the hard bounds.
Error: Species concentration 3-Methyl-2-oxobutyrate_m is out of the hard bounds.
Error: Species concentration Deoxyinosine_s is out of the hard bounds.
Error: Species concentration 7alpha-Hydroxycholest-4-en-3-one_c is out of the hard bounds.
ATP-binding Cassette (ABC) TCDB:3.A.1.208.8
Error: Species concentration Pantetheine_c is out of the hard bounds.
Warning: Species concentration Linolenoyl-CoA_c is out of the soft bounds.
Warning: Species concentration Glutamine_m is out of the soft bounds.
(S)-3-Hydroxytetradecanoyl-CoA hydro-lyase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:4.2.1.17
N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating) Aminosugars metabolism EC:1.14.18.2
Warning: Species concentration S-(2-Methylpropanoyl)-dihydrolipoamide_m is out of the soft bounds.
Error: Species concentration Bilirubin-bisglucuronoside_c is out of the hard bounds.
Error: Species concentration lauric-acid_s is out of the hard bounds.
Error: Species concentration Sphingosine_c is out of the hard bounds.
Warning: Species concentration O2_s is out of the soft bounds.
Error: Species concentration gamma-Linolenate_s is out of the hard bounds.
Warning: Species concentration 3-Oxododecanoyl-ACP_c is out of the soft bounds.
Warning: Species concentration Propinol_adenylate_m is out of the soft bounds.
L-Serine hydro-lyase (adding homocysteine) Glycine, serine and threonine metabolism / Methionine metabolism EC:4.2.1.22
Error: Species concentration Isovaleryl-CoA_m is out of the hard bounds.
Cytidine aminohydrolase Pyrimidine metabolism EC:3.5.4.5
Warning: Species concentration NADP+_c is out of the soft bounds.
Warning: Species concentration VLDL_s is out of the soft bounds.
Pyridoxine 5-phosphate:oxygen oxidoreductase (deaminating) Vitamin B6 metabolism EC:1.4.3.5
Error: Species concentration Propanoyl-CoA_c is out of the hard bounds.
Error: Species concentration O-Acetylcarnitine_p is out of the hard bounds.
Error: Species concentration 1-Pyrroline-5-carboxylate_c is out of the hard bounds.
Error: Species concentration CO2_m is out of the hard bounds.
Warning: Species concentration Butyryl-CoA_c is out of the soft bounds.
Error: Species concentration Aspartate_s is out of the hard bounds.
Warning: Species concentration Uracil_c is out of the soft bounds.
Error: Species concentration Collagen_COAA1_c is out of the hard bounds.
Propanoyl-CoA:(acceptor) 2,3-oxidoreductase beta-Alanine metabolism EC:1.3.3.6 EC:1.3.99.3
(5-Glutamyl)-peptide:amino-acid 5-glutamyltransferase Cyanoamino acid metabolism EC:2.3.2.2
Error: Species concentration 3-oxolaur-cis-5-enoyl-CoA_m is out of the hard bounds.
Error: Species concentration Fatty-acid-VLDL-PC-pool_c is out of the hard bounds.
Warning: Species concentration Putrescine_m is out of the soft bounds.
Warning: Species concentration Cytidine_s is out of the soft bounds.
Warning: Species concentration Pyruvate_m is out of the soft bounds.
Warning: Species concentration 3-oxooleoyl-CoA_m is out of the soft bounds.
Warning: Species concentration NADPH-redox-potential_m is out of the soft bounds.
Warning: Species concentration NADH_c is out of the soft bounds.
Error: Species concentration Vanillylmandelate_m is out of the hard bounds.
hydroxysteroid (17-beta) dehydrogenase 4 Bile acid biosynthesis EC:1.1.1.35
Warning: Species concentration Galactose_c is out of the soft bounds.
Warning: Species concentration Collagen_CO1A1_c is out of the soft bounds.
Warning: Species concentration AICAR_c is out of the soft bounds.
Warning: Species concentration dUDP_c is out of the soft bounds.
Warning: Species concentration Ethanol_c is out of the soft bounds.
Error: Species concentration (2E)-Tetradecenoyl-CoA_p is out of the hard bounds.
Error: Species concentration Linoleate_l is out of the hard bounds.
Warning: Species concentration Collagen_BGH3_c is out of the soft bounds.
Warning: Species concentration Linolenate_r is out of the soft bounds.
Warning: Species concentration Chenodeoxycholoyl-CoA_p is out of the soft bounds.
Warning: Species concentration Fe2+_m is out of the soft bounds.
Error: Species concentration Putrescine_c is out of the hard bounds.
3-Methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming) Valine, leucine and isoleucine degradation EC:6.4.1.4
Warning: Species concentration Fructose-1P_c is out of the soft bounds.
ATP:nucleoside-phosphate phosphotransferase Pyrimidine metabolism EC:2.7.4.4
Warning: Species concentration Linolenoyl-CoA_r is out of the soft bounds.
Error: Species concentration Collagen_CO6A5_c is out of the hard bounds.
Warning: Species concentration Deoxycytidine_s is out of the soft bounds.
Guanosine 5'-monophosphate phosphohydrolase Purine metabolism EC:3.1.3.5
Error: Species concentration Fumarate_m is out of the hard bounds.
5-Phospho-D-ribosylamine:glycine ligase (ADP-forming) Purine metabolism EC:6.3.4.13
Error: Species concentration S-glutathionyl-ethacrynic-acid_c is out of the hard bounds.
Error: Species concentration Oleoyl-CoA_c is out of the hard bounds.
Warning: Species concentration Phenylacetate_m is out of the soft bounds.
Error: Species concentration D-4-Phosphopantothenate_c is out of the hard bounds.
Warning: Species concentration gamma-Linolenate_s is out of the soft bounds.
(S)-Hydroxyoctanoyl-CoA hydro-lyase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:4.2.1.17
Error: Species concentration Fatty-acid-VLDL-SM-pool_c is out of the hard bounds.
Error: Species concentration N-Acetylneuraminate-9P_c is out of the hard bounds.
Choloyl-CoA:glycine N-choloyltransferase Bile acid biosynthesis / Taurine and hypotaurine metabolism EC:2.3.1.65
Warning: Species concentration Spermidine_c is out of the soft bounds.
Neurotransmitter:Sodium Symporter (NSS) TCDB:2.A.22.3.3
Error: Species concentration Bilirubin-bisglucuronoside_b is out of the hard bounds.
Warning: Species concentration GM1-pool_s is out of the soft bounds.
Warning: Species concentration Homoserine_s is out of the soft bounds.
ITP:D-Tagatose 6-phosphate 1-phosphotransferase Galactose metabolism EC:2.7.1.11
CMP-N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating) Aminosugars metabolism EC:1.14.18.2
Warning: Species concentration Glycogenin_c is out of the soft bounds.
Error: Species concentration Cholesterol-ester-palmn_r is out of the hard bounds.
Propanoate:CoA ligase (AMP-forming) Propanoate metabolism EC:6.2.1.1 EC:6.2.1.17
Warning: Species concentration 3-Hydroxyisobutyrate_m is out of the soft bounds.
Warning: Species concentration Oleate_r is out of the soft bounds.
Error: Species concentration 3-Oxohexadecanoyl-ACP_c is out of the hard bounds.
Warning: Species concentration taurolithocholate_c is out of the soft bounds.
Warning: Species concentration ApoB100_r is out of the soft bounds.
L-Glutamate:L-cysteine gamma-ligase (ADP-forming) Glutamate metabolism / Glutathione metabolism EC:6.3.2.2
Warning: Species concentration Glucosylceramide-pool_r is out of the soft bounds.
Warning: Species concentration CoA-activated_acetyl_group_r is out of the soft bounds.
sn-Glycerol-3-phosphate:NAD+ 2-oxidoreductase Glycerophospholipid metabolism EC:1.1.1.8
Error: Species concentration Phosphatidate-CL-pool_m is out of the hard bounds.
Warning: Species concentration Fatty-acid-VLDL-TG2-pool_c is out of the soft bounds.
Warning: Species concentration Glutamate_s is out of the soft bounds.
10-Formyltetrahydrofolate:5'-phosphoribosylglycinamide formyltransferase Purine metabolism / One carbon pool by folate EC:2.1.2.2
Warning: Species concentration (S)-3-Hydroxyhexadecanoyl-CoA_m is out of the soft bounds.
Warning: Species concentration Haptoglobin_c is out of the soft bounds.
Warning: Species concentration Nicotinate_s is out of the soft bounds.
Error: Species concentration sn-Glycerol-3P_m is out of the hard bounds.
Error: Species concentration H2O_p is out of the hard bounds.
3-Ketolactose galactohydrolase Galactose metabolism EC:3.2.1.23
collagen, type I, alpha 2 Protein assembly
collagen, type V, alpha 2 Protein assembly
Error: Species concentration 3-Sulfinoalanine_c is out of the hard bounds.
Error: Species concentration O-Butanoylcarnitine_m is out of the hard bounds.
Error: Species concentration O-Butanoylcarnitine_c is out of the hard bounds.
Error: Species concentration HMG-CoA_p is out of the hard bounds.
Error: Species concentration Methylthioribose-1P_c is out of the hard bounds.
UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific) Porphyrin and chlorophyll metabolism EC:2.4.1.17
Warning: Species concentration Crotonyl-CoA_m is out of the soft bounds.
L-Histidine:beta-alanine ligase (AMP-forming) Alanine and aspartate metabolism / Histidine metabolism / beta-Alanine metabolism EC:6.3.2.11
Error: Species concentration 1-Acylglycerol-3P-palmn_c is out of the hard bounds.
ATP:deoxyuridine 5'-phosphotransferase Pyrimidine metabolism EC:2.7.1.21
Error: Species concentration (2E)-Tetradecenoyl-ACP_c is out of the hard bounds.
Error: Species concentration Cholate_c is out of the hard bounds.
Error: Species concentration CDP-choline_c is out of the hard bounds.
Error: Species concentration 5-Phosphoribosylformylglycinamidine_c is out of the hard bounds.
Error: Species concentration Antitrypsin_l is out of the hard bounds.
Warning: Species concentration Methionine_m is out of the soft bounds.
5beta-Cholestane-3alpha,7alpha,12alpha-triol,NADPH:oxygen oxidoreductase (26-hydroxylating) Bile acid biosynthesis EC:1.14.13.15
Error: Species concentration Glycocholate_s is out of the hard bounds.
Warning: Species concentration Collagen_FMOD_c is out of the soft bounds.
Warning: Species concentration Trehalose_s is out of the soft bounds.
(S)-Hydroxydecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.35 EC:1.1.1.211
Error: Species concentration Glycogenin-G4G4_c is out of the hard bounds.
Error: Species concentration VLDL_r is out of the hard bounds.
Error: Species concentration Guanine_c is out of the hard bounds.
Warning: Species concentration ApoE_l is out of the soft bounds.
Error: Species concentration dGMP_c is out of the hard bounds.
3-Aminopropanoate:2-oxoglutarate aminotransferase Alanine and aspartate metabolism / beta-Alanine metabolism / Propanoate metabolism EC:2.6.1.55 EC:2.6.1.19
Warning: Species concentration Linolenate_s is out of the soft bounds.
Warning: Species concentration (R)-3-Hydroxybutanoate_c is out of the soft bounds.
Warning: Species concentration Proline_c is out of the soft bounds.
Ethanol:NAD+ oxidoreductase Glycolysis / Gluconeogenesis EC:1.1.1.1 EC:1.1.1.71
Warning: Species concentration Collagen_CO3A1_c is out of the soft bounds.
L-Arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) Arginine and proline metabolism EC:1.14.13.39
Warning: Species concentration 4alpha-Methylzymosterol-4-carboxylate_r is out of the soft bounds.
Warning: Species concentration ACP_c is out of the soft bounds.
Warning: Species concentration 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate_c is out of the soft bounds.
alpha-D-Glucoside glucohydrolase Galactose metabolism EC:3.2.1.48 EC:3.2.1.26
Warning: Species concentration Ceramide-1P-pool_c is out of the soft bounds.
Warning: Species concentration 2-Oxoadipate_m is out of the soft bounds.
Error: Species concentration GTP_s is out of the hard bounds.
Uridine:orthophosphate ribosyltransferase Pyrimidine metabolism EC:2.4.2.3
Warning: Species concentration Cholesterol_c is out of the soft bounds.
Warning: Species concentration Collagen_COCA1_c is out of the soft bounds.
6-Phospho-D-glucono-1,5-lactone lactonohydrolase Pentose phosphate pathway EC:3.1.1.31
Warning: Species concentration NH3_s is out of the soft bounds.
Error: Species concentration Stearate_c is out of the hard bounds.
Warning: Species concentration L-Palmitoylcarnitine_p is out of the soft bounds.
Warning: Species concentration Choloyl-CoA_c is out of the soft bounds.
Warning: Species concentration Cysteine_c is out of the soft bounds.
Warning: Species concentration Glycogenin-G4G4_c is out of the soft bounds.
Octanoyl-CoA:acetyl-CoA C-acyltransferase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:2.3.1.16
Error: Species concentration Arginine_c is out of the hard bounds.
Warning: Species concentration Acetylcholine_c is out of the soft bounds.
Warning: Species concentration glycoursodeoxycholate_c is out of the soft bounds.
trans-Dec-2-enoyl-CoA reductase Fatty acid elongation in mitochondria EC:1.3.1.38
Error: Species concentration GMP_c is out of the hard bounds.
xylitol:NAD oxidoreductase Pentose and glucuronate interconversions EC:1.1.1.15
Error: Species concentration CTP_m is out of the hard bounds.
5-Hydroxyindoleacetaldehyde:oxygen oxidoreductase Tryptophan metabolism EC:1.2.3.1
Warning: Species concentration Dihydrofolate_m is out of the soft bounds.
(R)-2-Methyl-3-oxopropanoyl-CoA CoA-carbonylmutase Valine, leucine and isoleucine degradation / Propanoate metabolism EC:5.4.99.2
2-Oxoadipate:lipoamde 2-oxidoreductase(decarboxylating and acceptor-succinylating) Lysine degradation EC:1.2.4.2
dTDP diphosphohydrolase Pyrimidine metabolism EC:3.6.1.5
Warning: Species concentration CoA_r is out of the soft bounds.
Error: Species concentration Porphobilinogen_c is out of the hard bounds.
Error: Species concentration Cholesterol_b is out of the hard bounds.
Warning: Species concentration (2E)-Octenoyl-ACP_c is out of the soft bounds.
Error: Species concentration Phosphatidate-VLDL-PS-pool_c is out of the hard bounds.
Warning: Species concentration 2-Oxobutyrate_c is out of the soft bounds.
L-Cystathionine Lysteine-lyase (deaminating) Glycine, serine and threonine metabolism / Methionine metabolism / Nitrogen metabolism EC:4.4.1.1
Warning: Species concentration Methylmalonate_m is out of the soft bounds.
Octanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) Fatty acid biosynthesis EC:2.3.1.85
ITP diphosphohydrolase Purine metabolism EC:3.6.1.5
Warning: Species concentration Bilirubin-monoglucuronoside_c is out of the soft bounds.
Error: Species concentration Acetylcholine_s is out of the hard bounds.
Warning: Species concentration Triacylglycerol-VLDL-pool_r is out of the soft bounds.
Warning: Species concentration Formate_m is out of the soft bounds.
Error: Species concentration Glycocholate_c is out of the hard bounds.
Warning: Species concentration GDP-activated-fucose_c is out of the soft bounds.
Error: Species concentration O-Propanoylcarnitine_c is out of the hard bounds.
Warning: Species concentration Acetyl-ACP_c is out of the soft bounds.
Warning: Species concentration Palmitolate_c is out of the soft bounds.
NADH:6,7-dihydropteridine oxidoreductase Folate biosynthesis EC:1.5.1.34
Warning: Species concentration Ubiquinone_m is out of the soft bounds.
Error: Species concentration (R)-4-Phosphopantothenoyl-cysteine_m is out of the hard bounds.
Warning: Species concentration Proton-gradient_c is out of the soft bounds.
Warning: Species concentration Palmitate_s is out of the soft bounds.
Deoxyadenosine:orthophosphate ribosyltransferase Purine metabolism EC:2.4.2.1
Warning: Species concentration decanoic-acid_c is out of the soft bounds.
Warning: Species concentration Zinc_c is out of the soft bounds.
Error: Species concentration 7alpha,12alpha-Dihydroxycholest-4-en-3-one_r is out of the hard bounds.
Warning: Species concentration DHAP_c is out of the soft bounds.
Warning: Species concentration Cholesterol-ester-ala_r is out of the soft bounds.
(S)-Hydroxyhexanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.211 EC:1.1.1.35
Error: Species concentration 3-Oxohexanoyl-ACP_c is out of the hard bounds.
Error: Species concentration N-Formimino-L-glutamate_c is out of the hard bounds.
Error: Species concentration (S)-3-Hydroxydodecanoyl-CoA_p is out of the hard bounds.
Error: Species concentration PAPS_c is out of the hard bounds.
Warning: Species concentration Dehydroepiandrosterone_sulfate_s is out of the soft bounds.
Warning: Species concentration Ribitol_c is out of the soft bounds.
ATP:riboflavin 5'-phosphotransferase Riboflavin metabolism EC:2.7.1.26
Error: Species concentration Thymidine_s is out of the hard bounds.
L-Alanine:2-oxoglutarate aminotransferase Glutamate metabolism / Alanine and aspartate metabolism EC:2.6.1.2
Error: Species concentration Na-gradient_c is out of the hard bounds.
Warning: Species concentration 6-Deoxy-L-galactose_c is out of the soft bounds.
Error: Species concentration Homoserine_c is out of the hard bounds.
Error: Species concentration Guanosine_m is out of the hard bounds.
Error: Species concentration Chitin-component_s is out of the hard bounds.
Warning: Species concentration Pyruvate_p is out of the soft bounds.
ATP-binding Cassette (ABC) TCDB:3.A.1.203.1
Error: Species concentration Asparagine_l is out of the hard bounds.
Dihydrolipoamide:NAD+ oxidoreductase EC:1.8.1.4
Warning: Species concentration Collagen_CO4A2_c is out of the soft bounds.
Warning: Species concentration SM-pool_l is out of the soft bounds.
Error: Species concentration Deoxyguanosine_c is out of the hard bounds.
Warning: Species concentration Antichymotrypsin_l is out of the soft bounds.
UDP-N-acetyl-D-glucosamine 2-epimerase Aminosugars metabolism EC:5.1.3.14
Warning: Species concentration 1,2-Diacylglycerol-VLDL-SM-pool_c is out of the soft bounds.
Error: Species concentration NH4+_s is out of the hard bounds.
Error: Species concentration Oxalosuccinate_p is out of the hard bounds.
Warning: Species concentration gamma-Linolenate_c is out of the soft bounds.
5beta-Cholestane-3alpha,7alpha,12alpha,26-tetraol:NAD+ 26-oxidoreductase Bile acid biosynthesis EC:1.1.1.161
Warning: Species concentration prostaglandin-e2_c is out of the soft bounds.
Error: Species concentration (2E)-Dodecenoyl-CoA_p is out of the hard bounds.
Propanoate:CoA ligase (AMP-forming) EC:6.2.1.17 EC:6.2.1.1
Warning: Species concentration Phosphocholine_c is out of the soft bounds.
Error: Species concentration Acetoacetate_m is out of the hard bounds.
Biosynthesis of steroids Enzyme catalyzed
Warning: Species concentration 3-Keto-4-methylzymosterol_r is out of the soft bounds.
Warning: Species concentration 5beta-Cholestane-3alpha,7alpha-diol_c is out of the soft bounds.
Warning: Species concentration ADP_s is out of the soft bounds.
Error: Species concentration Dehydroalanine_c is out of the hard bounds.
Error: Species concentration CoA-activated_acetyl_group_m is out of the hard bounds.
Error: Species concentration Homocarnosine_c is out of the hard bounds.
Error: Species concentration PRPP_c is out of the hard bounds.
Warning: Species concentration Albumin_c is out of the soft bounds.
dUTP:cytidine 5'-phosphotransferase Pyrimidine metabolism EC:2.7.1.48
Hydroxymethylbilane hydro-lyase(cyclizing) Porphyrin and chlorophyll metabolism EC:4.2.1.75
Error: Species concentration NADP+_c is out of the hard bounds.
Warning: Species concentration beta-Alanine_m is out of the soft bounds.
Warning: Species concentration O-Acetylcarnitine_m is out of the soft bounds.
Sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase Pentose phosphate pathway EC:2.2.1.2
Warning: Species concentration CDP_m is out of the soft bounds.
Warning: Species concentration CO2_s is out of the soft bounds.
Ferrocytochrome-c:oxygen oxidoreductase Oxidative phosphorylation EC:1.9.3.1
[Acyl-carrier-protein] 4'-pantetheine-phosphohydrolase Pantothenate and CoA biosynthesis EC:3.1.4.14
Error: Species concentration palmitoleoyl-Carnitine_m is out of the hard bounds.
Error: Species concentration 3-Oxooctanoyl-CoA_m is out of the hard bounds.
Warning: Species concentration N-Acetylglucosamine_r is out of the soft bounds.
ATP:nicotinamide-nucleotide adenylyltransferase Nicotinate and nicotinamide metabolism EC:2.7.7.18
Warning: Species concentration Adenylyl_sulfate_c is out of the soft bounds.
Warning: Species concentration Thiamin_s is out of the soft bounds.
Warning: Species concentration Cysteine_s is out of the soft bounds.
Warning: Species concentration palmitoleoyl-Carnitine_m is out of the soft bounds.
Guanosine 3',5'-cyclic phosphate 5'-nucleotidohydrolase Purine metabolism EC:3.1.4.17 EC:3.1.4.35
Warning: Species concentration CMP-activated-N-acetylneuraminate_n is out of the soft bounds.
UDPglucose:NAD+ oxidoreductase Pentose and glucuronate interconversions / Nucleotide sugars metabolism EC:1.1.1.22
Error: Species concentration Acyl-CoA-VLDL-TG2-pool_c is out of the hard bounds.
Error: Species concentration Cholestenol_r is out of the hard bounds.
Warning: Species concentration Homocysteine_c is out of the soft bounds.
Warning: Species concentration Taurine_p is out of the soft bounds.
Warning: Species concentration dGTP_m is out of the soft bounds.
Sulfite:oxygen oxidoreductase Sulfur metabolism EC:1.8.3.1
Warning: Species concentration GSH_s is out of the soft bounds.
NADH:guanosine-5'-phosphate oxidoreductase(deaminating) Purine metabolism EC:1.7.1.7
Error: Species concentration NADH_c is out of the hard bounds.
Warning: Species concentration (S)-Dihydroorotate_c is out of the soft bounds.
Warning: Species concentration ApoA1_c is out of the soft bounds.
Warning: Species concentration Cystine_s is out of the soft bounds.
Warning: Species concentration 2-Lysolecithin-pool_c is out of the soft bounds.
Monovalent Cation:Proton Antiporter-1 (CPA1) TCDB:2.A.36.1.1
Error: Species concentration Choloyl-CoA_r is out of the hard bounds.
Warning: Species concentration mitoApo-ACP_m is out of the soft bounds.
Error: Species concentration dCDP_c is out of the hard bounds.
Error: Species concentration AICAR_c is out of the hard bounds.
Warning: Species concentration (S)-3-hydroxyoleyleoyl-CoA_m is out of the soft bounds.
Warning: Species concentration Activated_methyl_group_c is out of the soft bounds.
Warning: Species concentration Zymosterol_r is out of the soft bounds.
Warning: Species concentration 4-Nitrophenyl-P_s is out of the soft bounds.
Warning: Species concentration HDL_l is out of the soft bounds.
S-Adenosyl-L-methionine:phosphodimethylethanolamine N-methyltransferase Glycerophospholipid metabolism EC:2.1.1.103
Error: Species concentration linoleic-Carnitine_r is out of the hard bounds.
Error: Species concentration AIR_c is out of the hard bounds.
Error: Species concentration Ferricytochrome_b5_c is out of the hard bounds.
S-(hydroxymethyl)glutathione synthase Methane metabolism EC:4.4.1.22
Error: Species concentration N-Acetylglucosamine-1P_c is out of the hard bounds.
Error: Species concentration 2PG_c is out of the hard bounds.
Warning: Species concentration (R)-3-Hydroxydecanoyl-ACP_c is out of the soft bounds.
Warning: Species concentration cGMP_c is out of the soft bounds.
Major Facilitator(MFS) TCDB:2.A.1.13.1 2.A.1.13.
trans-Oct-2-enoyl-CoA reductase Fatty acid elongation in mitochondria EC:1.3.1.38
Error: Species concentration Uridine_c is out of the hard bounds.
Error: Species concentration ADP_p is out of the hard bounds.
5,6,7,8-Tetrahydrofolate:NADP+ oxidoreductase One carbon pool by folate / Folate biosynthesis EC:1.5.1.3
(R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase EC:2.6.1.40
Warning: Species concentration CDP-diacylglycerol-VLDL-PI-pool_l is out of the soft bounds.
Error: Species concentration Thioredoxin-redox-potential_c is out of the hard bounds.
Warning: Species concentration Cholate_r is out of the soft bounds.
Error: Species concentration cis-myrist-7-enoyl-CoA_m is out of the hard bounds.
Warning: Species concentration ITP_s is out of the soft bounds.
L-Aspartate 1-carboxy-lyase Alanine and aspartate metabolism / beta-Alanine metabolism EC:4.1.1.11
Error: Species concentration CMP_s is out of the hard bounds.
Warning: Species concentration 3-Oxopalmitoyl-CoA_m is out of the soft bounds.
Error: Species concentration Phenylacetate_m is out of the hard bounds.
Error: Species concentration Sedoheptulose-7P_c is out of the hard bounds.
Warning: Species concentration Lipoamide_m is out of the soft bounds.
Error: Species concentration Protoporphyrinogen_IX_m is out of the hard bounds.
Warning: Species concentration Xanthine_p is out of the soft bounds.
Error: Species concentration L-3-Cyanoalanine_s is out of the hard bounds.
UDP diphosphohydrolase Pyrimidine metabolism EC:3.6.1.6
Warning: Species concentration Glycogenin-G11_c is out of the soft bounds.
2-(Formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming) Purine metabolism EC:6.3.3.1
Warning: Species concentration Fe2+_c is out of the soft bounds.
Warning: Species concentration (R)-Mevalonate_p is out of the soft bounds.
Warning: Species concentration N-Acetylglucosamine-6P_c is out of the soft bounds.
Warning: Species concentration Formaldehyde_s is out of the soft bounds.
Error: Species concentration Ribose_s is out of the hard bounds.
Warning: Species concentration CDP-diacylglycerol-VLDL-PI-pool_c is out of the soft bounds.
Error: Species concentration Dihydrothymine_c is out of the hard bounds.
Warning: Species concentration 5,6-Dihydrouracil_c is out of the soft bounds.
Error: Species concentration Ribose-5P_c is out of the hard bounds.
Warning: Species concentration Bilirubin-bisglucuronoside_r is out of the soft bounds.
Error: Species concentration FADH2_c is out of the hard bounds.
Error: Species concentration 6-Pyruvoyltetrahydropterin_c is out of the hard bounds.
Warning: Species concentration HCO3-_s is out of the soft bounds.
UTP diphosphohydrolase Pyrimidine metabolism EC:3.6.1.5
sphingosine kinase Sphingolipid metabolism EC:2.7.1.91
Warning: Species concentration tauroursodeoxycholate_c is out of the soft bounds.
Warning: Species concentration ApoE_c is out of the soft bounds.
Error: Species concentration GMP_m is out of the hard bounds.
Warning: Species concentration Cholesterol-ester-palm_l is out of the soft bounds.
Warning: Species concentration Arachidonyl-Carnitine_r is out of the soft bounds.
ATP-binding Cassette (ABC) TCDB:3.A.1.208.2
Error: Species concentration Fructose_c is out of the hard bounds.
Warning: Species concentration Tetradecanoyl-ACP_c is out of the soft bounds.
Error: Species concentration Glyceraldehyde_c is out of the hard bounds.
GTP 7,8-8,9-dihydrolase Folate biosynthesis EC:3.5.4.16
Warning: Species concentration Prothrombin_s is out of the soft bounds.
Warning: Species concentration N-Acetylneuraminate_c is out of the soft bounds.
Error: Species concentration NAD+_p is out of the hard bounds.
steroyl-CoA,hydrogen-donor:oxygen oxidoreductase Polyunsaturated fatty acid biosynthesis EC:1.14.19.1
Error: Species concentration CoA-activated_acetyl_group_r is out of the hard bounds.
Error: Species concentration ATP_l is out of the hard bounds.
Error: Species concentration N-Acetyl-D-mannosamine_c is out of the hard bounds.
GMP:pyrophosphate phosphoribosyltransferase Purine metabolism EC:2.4.2.8
Warning: Species concentration sn-Glycerol-3P_c is out of the soft bounds.
Acetate:CoA ligase (AMP-forming) Glycolysis / Gluconeogenesis EC:6.2.1.1
Cholest-5-ene-3beta,7alpha-diol:NAD+ 3-oxidoreductase Bile acid biosynthesis EC:1.1.1.181
Error: Species concentration Glutamine_c is out of the hard bounds.
Error: Species concentration 1-Acylglycerol-VLDL-PE-pool_c is out of the hard bounds.
(S)-3-Hydroxy-3-methylglutaryl-CoA acetoacetate-lyase Synthesis and degradation of ketone bodies / Valine, leucine and isoleucine degradation / Butanoate metabolism EC:4.1.3.4
Warning: Species concentration PI-pool_l is out of the soft bounds.
Solute:Sodium Symporter (SSS) TCDB:2.A.21.3.6
Warning: Species concentration Na+_c is out of the soft bounds.
Error: Species concentration (2E)-Decenoyl-CoA_m is out of the hard bounds.
Error: Species concentration Spermine_c is out of the hard bounds.
Error: Species concentration Glycine_m is out of the hard bounds.
Error: Species concentration Fibrinogen_c is out of the hard bounds.
Error: Species concentration ApoC2_r is out of the hard bounds.
(R)-Mevalonate:NADP+ oxidoreductase (CoA acylating) Biosynthesis of steroids EC:1.1.1.34
Warning: Species concentration dADP_c is out of the soft bounds.
lanosterol D24-reductase Biosynthesis of steroids EC:1.3.1.72
Warning: Species concentration 1-Acylglycerol-3P-palm_c is out of the soft bounds.
Error: Species concentration Protein_lysine_c is out of the hard bounds.
Warning: Species concentration Hydroxypyruvate_c is out of the soft bounds.
Error: Species concentration NO_s is out of the hard bounds.
Warning: Species concentration GDP-activated-mannose_c is out of the soft bounds.
Error: Species concentration Hypoxanthine_c is out of the hard bounds.
Warning: Species concentration ATP_l is out of the soft bounds.
Error: Species concentration (R)-Methylmalonyl-CoA_m is out of the hard bounds.
Warning: Species concentration O2_r is out of the soft bounds.
Warning: Species concentration Glycogenin-G7G1_c is out of the soft bounds.
Error: Species concentration 1-Pyrroline-5-carboxylate_m is out of the hard bounds.
Error: Species concentration GAR_c is out of the hard bounds.
Amino Acid-Polyamine-Organocation (APC) TCDB:2.A.3.3.2
Warning: Species concentration Isomaltose_s is out of the soft bounds.
Warning: Species concentration dCMP_c is out of the soft bounds.
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 Protein assembly
Error: Species concentration GSH_c is out of the hard bounds.
Warning: Species concentration Deoxycytidine_c is out of the soft bounds.
Error: Species concentration Carbonate_s is out of the hard bounds.
Warning: Species concentration L-Lactate_c is out of the soft bounds.
Warning: Species concentration Adenylosuccinate_c is out of the soft bounds.
Error: Species concentration SM-pool_b is out of the hard bounds.
Error: Species concentration S-(2-Methylbutanoyl)-dihydrolipoamide_m is out of the hard bounds.
Warning: Species concentration Lepidimoide_s is out of the soft bounds.
Warning: Species concentration 10-Formyl-THF_m is out of the soft bounds.
Error: Species concentration ApoTransferin_s is out of the hard bounds.
Warning: Species concentration UDP-glucose_s is out of the soft bounds.
Error: Species concentration Glutamine_l is out of the hard bounds.
Warning: Species concentration L-Cystathionine_c is out of the soft bounds.
Warning: Species concentration Acetyl-CoA_c is out of the soft bounds.
Warning: Species concentration Ribose-1P_c is out of the soft bounds.
Error: Species concentration prostaglandin-d1_s is out of the hard bounds.
membrane alanyl aminopeptidase Glutathione metabolism EC:3.4.11.2
Error: Species concentration Cysteine_c is out of the hard bounds.
Warning: Species concentration FMN_c is out of the soft bounds.
Error: Species concentration Collagen_CO4A5_c is out of the hard bounds.
phosphatidylserine synthase 2 Glycerophospholipid metabolism EC:2.7.8.-
Squalene,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing) Biosynthesis of steroids EC:1.14.99.7
ATP:pantothenate 4'-phosphotransferase Pantothenate and CoA biosynthesis EC:2.7.1.33
Warning: Species concentration Lysine_l is out of the soft bounds.
Error: Species concentration Collagen_COCA1_c is out of the hard bounds.
Error: Species concentration glutathionyl-leuc4_c is out of the hard bounds.
Warning: Species concentration OAA_m is out of the soft bounds.
Error: Species concentration Cys-Gly_c is out of the hard bounds.
5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase Glycine, serine and threonine metabolism / One carbon pool by folate EC:2.1.2.1
Warning: Species concentration ITP_c is out of the soft bounds.
Error: Species concentration CMP_c is out of the hard bounds.
Error: Species concentration Galactosylglycerol_s is out of the hard bounds.
Error: Species concentration 3-Hydroxy-L-kynurenine_c is out of the hard bounds.
Error: Species concentration Protoporphyrinogen_IX_c is out of the hard bounds.
Warning: Species concentration H2O_r is out of the soft bounds.
Error: Species concentration Succinyl-CoA_m is out of the hard bounds.
Xanthosine-5'-phosphate:ammonia ligase (AMP-forming) Purine metabolism EC:6.3.4.1
Warning: Species concentration CTP_c is out of the soft bounds.
Error: Species concentration Methylmalonate_m is out of the hard bounds.
Warning: Species concentration 7alpha-Hydroxycholest-4-en-3-one_r is out of the soft bounds.
Error: Species concentration Guanidinoacetate_c is out of the hard bounds.
Warning: Species concentration S-glutathionyl-ethacrynic-acid_b is out of the soft bounds.
Warning: Species concentration Succinate_c is out of the soft bounds.
UTP:pyruvate O2-phosphotransferase EC:2.7.1.40
Warning: Species concentration Bilirubin-bisglucuronoside_b is out of the soft bounds.
Warning: Species concentration myristic-acid_c is out of the soft bounds.
Warning: Species concentration lauric-acid_c is out of the soft bounds.
Warning: Species concentration 2-Deoxy-D-ribose-1P_c is out of the soft bounds.
Warning: Species concentration Ribose-5P_c is out of the soft bounds.
Warning: Species concentration Dephospho-CoA_c is out of the soft bounds.
butyryl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) Fatty acid biosynthesis EC:2.3.1.85
Oleoyl-[acyl-carrier-protein] hydrolase Fatty acid biosynthesis EC:2.3.1.85
Error: Species concentration Collagen_COEA1_c is out of the hard bounds.
Error: Species concentration SAM_c is out of the hard bounds.
Warning: Species concentration Collagen_CO9A1_c is out of the soft bounds.
Error: Species concentration 3-Oxododecanoyl-ACP_c is out of the hard bounds.
Error: Species concentration gamma-Linolenate_l is out of the hard bounds.
N6-(1,2-Dicarboxyethyl)AMP AMP-lyase Purine metabolism / Alanine and aspartate metabolism EC:4.3.2.2
Warning: Species concentration PI-pool_c is out of the soft bounds.
collagen, type I, alpha 1 Protein assembly
Error: Species concentration Cholesterol-ester-ala_r is out of the hard bounds.
Warning: Species concentration (S)-3-Hydroxydodecanoyl-CoA_m is out of the soft bounds.
Error: Species concentration Glutamate_c is out of the hard bounds.
Error: Species concentration Cholesterol-ester-pool_r is out of the hard bounds.
UTP:Sedoheptulose 7-phosphate 1-phosphotransferase EC:2.7.1.11
Warning: Species concentration But-2-enoyl-ACP_c is out of the soft bounds.
Error: Species concentration Citrate_s is out of the hard bounds.
3'-Phospho-5'-adenylyl sulfate 3'(2')-phosphohydrolase Sulfur metabolism EC:3.1.3.7
Sphingomyelin cholinephosphohydrolase Sphingolipid metabolism EC:3.1.4.12
Error: Species concentration Uracil_c is out of the hard bounds.
Warning: Species concentration Cholesterol-ester-palm_r is out of the soft bounds.
Error: Species concentration Thioredoxin_c is out of the hard bounds.
Warning: Species concentration ApoB100_l is out of the soft bounds.
Warning: Species concentration cis-laur-5-enoyl-CoA_m is out of the soft bounds.
Warning: Species concentration Hexadecenal_c is out of the soft bounds.
Error: Species concentration Acetone_s is out of the hard bounds.
Warning: Species concentration Fatty-acid-VLDL-PC-pool_l is out of the soft bounds.
Error: Species concentration Stearate_l is out of the hard bounds.
Warning: Species concentration Sulfate_b is out of the soft bounds.
Warning: Species concentration Glutamate_c is out of the soft bounds.
3-Methoxy-4-hydroxyphenylacetaldehyde:NADP+ oxidoreductase Tyrosine metabolism EC:1.2.1.5
Warning: Species concentration Mannose-1P_c is out of the soft bounds.
Error: Species concentration 3-oxooleoyl-CoA_m is out of the hard bounds.
Warning: Species concentration Riboflavin_c is out of the soft bounds.
L-Glutamine amidohydrolase D-Glutamine and D-glutamate metabolism EC:3.5.1.2 EC:3.5.1.38
Error: Species concentration sn-Glycerol-3P_c is out of the hard bounds.
Warning: Species concentration dGDP_c is out of the soft bounds.
Error: Species concentration prostaglandin-e2_c is out of the hard bounds.
Error: Species concentration Chenodiol_c is out of the hard bounds.
7alpha-Hydroxy-5beta-cholestan-3-one:(acceptor) delta4-oxidoreductase; 7alpha-Hydroxy-5beta-cholestan-3-one:NADP+ delta4-oxidoreductase Bile acid biosynthesis EC:1.3.99.6
Error: Species concentration Collagen_CO9A1_c is out of the hard bounds.
Error: Species concentration N-Acetyl-D-mannosamine_r is out of the hard bounds.
Error: Species concentration Galactose_c is out of the hard bounds.
Error: Species concentration 3-Keto-4-methylzymosterol_r is out of the hard bounds.
CTP diphosphohydrolase Pyrimidine metabolism EC:3.6.1.5
Error: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanate_r is out of the hard bounds.
Error: Species concentration leukotriene-b4_s is out of the hard bounds.
Error: Species concentration ADP_s is out of the hard bounds.
Warning: Species concentration Linoleate_s is out of the soft bounds.
Error: Species concentration 1,2-Diacylglycerol-VLDL-TG-pool_c is out of the hard bounds.
Warning: Species concentration UDP_s is out of the soft bounds.
Error: Species concentration Collagen_COMA1_c is out of the hard bounds.
NADH:ubiquinone oxidoreductase Oxidative phosphorylation EC:1.6.5.3
Collagen alpha-1(V) chain Protein assembly
Error: Species concentration Collagen_CCBE1_c is out of the hard bounds.
Error: Species concentration Xanthurenate_c is out of the hard bounds.
ATP:D-glyceraldehyde 3-phosphotransferase Fructose and mannose metabolism EC:2.7.1.28
Error: Species concentration 3,4-Dihydroxymandelaldehyde_m is out of the hard bounds.
Error: Species concentration Fructose-1P_c is out of the hard bounds.
Warning: Species concentration THF_m is out of the soft bounds.
Warning: Species concentration L-Formylkynurenine_c is out of the soft bounds.
Warning: Species concentration Malonyl-Carnitin_p is out of the soft bounds.
2'-Deoxyuridine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase Pyrimidine metabolism EC:1.17.4.1
Warning: Species concentration Collagen_CO6A3_c is out of the soft bounds.
Error: Species concentration (S)-3-Hydroxy-2-methylbutyryl-CoA_m is out of the hard bounds.
L-Ornithine carboxy-lyase Urea cycle and metabolism of amino groups EC:4.1.1.17
Warning: Species concentration Fumarate_c is out of the soft bounds.
Error: Species concentration Deoxycytidine_c is out of the hard bounds.
Error: Species concentration Cysteine_s is out of the hard bounds.
Error: Species concentration 2-Oxoglutaramate_m is out of the hard bounds.
Error: Species concentration Collagen_FCN1_c is out of the hard bounds.
Warning: Species concentration trans,cis-myristo-2,7-dienoyl-CoA_m is out of the soft bounds.
Warning: Species concentration palmitoleoyl-CoA_r is out of the soft bounds.
Warning: Species concentration Nicotinamide_s is out of the soft bounds.
Acetaldehyde:NAD+ oxidoreductase Glycolysis / Gluconeogenesis / Pyruvate metabolism EC:1.2.1.3 EC:1.2.1.5
Error: Species concentration Glycochenodeoxycholate_b is out of the hard bounds.
Error: Species concentration Retinoate_s is out of the hard bounds.
Error: Species concentration (S)-Dihydroorotate_c is out of the hard bounds.
Error: Species concentration Cholesterol-ester-stea_r is out of the hard bounds.
Error: Species concentration Cystine_s is out of the hard bounds.
Warning: Species concentration 5beta-Cholestane-3alpha,7alpha-diol_m is out of the soft bounds.
dATP:pyruvate O2-phosphotransferase Purine metabolism EC:2.7.1.40
Error: Species concentration cis-(3S)-hydroxytetradec-7-enoyl-CoA_m is out of the hard bounds.
Error: Species concentration GDP-activated-mannose_c is out of the hard bounds.
Error: Species concentration N-Acetylneuraminate_c is out of the hard bounds.
Warning: Species concentration 1-Acylglycerol-3P-VLDL-TG1-pool_c is out of the soft bounds.
Error: Species concentration Fructose-2,6PP_c is out of the hard bounds.
Error: Species concentration (S)-3-hydroxyoleyleoyl-CoA_m is out of the hard bounds.
N-Formylanthranilate amidohydrolase Tryptophan metabolism EC:3.5.1.9
3-Hydroxy-2-methylpropanoate:NAD+ oxidoreductase EC:1.1.1.31
Warning: Species concentration 2-Aminomuconate_semialdehyde_c is out of the soft bounds.
D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D- galactosyl-D-glucosylceramide galactohydrolase EC:3.2.1.23
Error: Species concentration glycolithocholate_c is out of the hard bounds.
Warning: Species concentration Elaidate_c is out of the soft bounds.
Error: Species concentration ApoB100_r is out of the hard bounds.
ATP:deoxyguanosine 5'-phosphotransferase Purine metabolism EC:2.7.1.113
pyridoxal-5'-phosphate phosphohydrolase Vitamin B6 metabolism EC:3.1.3.74
Error: Species concentration Fatty-acid-VLDL-PC-pool_r is out of the hard bounds.
Guanine aminohydrolase Purine metabolism EC:3.5.4.3
7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one:(acceptor) delta4-oxidoreductase; 7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one:NADP+ delta4-oxidoreductase Bile acid biosynthesis EC:1.3.1.3
Warning: Species concentration Oleate_l is out of the soft bounds.
Error: Species concentration linoleic-Carnitine_p is out of the hard bounds.
Warning: Species concentration Acetaldehyde_s is out of the soft bounds.
L-serine ammonia-lyase Glycine, serine and threonine metabolism EC:4.3.1.17
Error: Species concentration Haptoglobin_c is out of the hard bounds.
Warning: Species concentration H2O_m is out of the soft bounds.
Error: Species concentration 5beta-Cholestane-3alpha,7alpha,12alpha,26-tetrol_c is out of the hard bounds.
Warning: Species concentration N-Pantothenoylcysteine_m is out of the soft bounds.
Warning: Species concentration dTMP_m is out of the soft bounds.
Warning: Species concentration Phenylacetaldehyde_m is out of the soft bounds.
Warning: Species concentration GSH-potential_c is out of the soft bounds.
Error: Species concentration Phosphopantetheine_c is out of the hard bounds.
2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate lyase Folate biosynthesis EC:4.2.3.12
Warning: Species concentration O-Propanoylcarnitine_m is out of the soft bounds.
Succinyl-CoA:glycine C-succinyl-transferase(decarboxylating) EC:2.3.1.37
Warning: Species concentration N-Carbamoyl-L-aspartate_c is out of the soft bounds.
4-Fumarylacetoacetate fumarylhydrola Tyrosine metabolism / Styrene degradation EC:3.7.1.2
Error: Species concentration D-3-Amino-isobutanoate_m is out of the hard bounds.
(S)-2,3-Epoxysqualene mutase (cyclizing, lanosterol-forming) Biosynthesis of steroids EC:5.4.99.7
Warning: Species concentration 1-Acylglycerol-3P-Bile-PC-pool_c is out of the soft bounds.
4-methyl-2-oxopentanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating) EC:1.2.4.4
Warning: Species concentration Cholesterol-ester-arach_l is out of the soft bounds.
Warning: Species concentration LTD4_s is out of the soft bounds.
Error: Species concentration (R)-Mevalonate_p is out of the hard bounds.
Warning: Species concentration CDP-choline_r is out of the soft bounds.
(S)-3-Hydroxy-3-methylglutaryl-CoA hydro-lyase Valine, leucine and isoleucine degradation EC:4.2.1.18
3-Methoxy-4-hydroxyphenylglycolaldehyde:NAD+ oxidoreductase Tyrosine metabolism EC:1.2.1.5
Warning: Species concentration Antitrypsin_s is out of the soft bounds.
Error: Species concentration Dihomo-gamma-linolenate_l is out of the hard bounds.
Warning: Species concentration Octanoyl-CoA_m is out of the soft bounds.
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 Protein assembly
D-Glycerate:NADP+ 2-oxidoreductase Glycine, serine and threonine metabolism EC:1.1.1.81
Warning: Species concentration 3-oxopalmitoleoyl-CoA_m is out of the soft bounds.
Warning: Species concentration NADPH_p is out of the soft bounds.
ATP:glycerol 3-phosphotransferase Glycerolipid metabolism EC:2.7.1.30
ATP:N-acetyl-D-glucosamine 6-phosphotransferase Glutamate metabolism / Aminosugars metabolism EC:2.7.1.59
Warning: Species concentration ApoTransferin_l is out of the soft bounds.
D-Fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase Carbon fixation EC:2.2.1.1
Warning: Species concentration (2E)-Hexadecenoyl-CoA_m is out of the soft bounds.
Error: Species concentration Proline_c is out of the hard bounds.
Error: Species concentration UDP-glucose_r is out of the hard bounds.
Warning: Species concentration Formamidopyrimidine_nleoside_triphosphate_c is out of the soft bounds.
Error: Species concentration Palmitoyl-CoA_m is out of the hard bounds.
Error: Species concentration Dehydroepiandrosterone_sulfate_c is out of the hard bounds.
Warning: Species concentration prostaglandin-a1_c is out of the soft bounds.
Neurotransmitter:Sodium Symporter (NSS) TCDB:2.A.22.3.4
Warning: Species concentration Sulfite_m is out of the soft bounds.
Error: Species concentration leukotriene-a4_s is out of the hard bounds.
Warning: Species concentration Succinate_m is out of the soft bounds.
Error: Species concentration Noradrenaline_c is out of the hard bounds.
Error: Species concentration Acyl-CoA-Bile-PC-pool_c is out of the hard bounds.
Warning: Species concentration Glucosamine_c is out of the soft bounds.
Error: Species concentration NH3_s is out of the hard bounds.
Warning: Species concentration Stearate_r is out of the soft bounds.
Warning: Species concentration 4-Imidazolone-5-propanoate_c is out of the soft bounds.
Warning: Species concentration FAD_m is out of the soft bounds.
Error: Species concentration H2S2O3_c is out of the hard bounds.
Error: Species concentration Desmosterol_r is out of the hard bounds.
(S)-Dihydroorotate:(acceptor) oxidoreductase; (S)-Dihydroorotate:NAD+ oxidoreductase Pyrimidine metabolism EC:1.3.1.14
trans-4-Hydroxy-L-proline:NADP+ 5-oxidoreductase Arginine and proline metabolism EC:1.5.1.2
Error: Species concentration PI-pool_l is out of the hard bounds.
IMP 1,2-hydrolase (decyclizing) Purine metabolism EC:3.5.4.10
Error: Species concentration Linoleate_p is out of the hard bounds.
Error: Species concentration NAD+_m is out of the hard bounds.
Warning: Species concentration 3-Keto-beta-D-galactose_s is out of the soft bounds.
Warning: Species concentration Fe3+_s is out of the soft bounds.
Error: Species concentration Butyryl-CoA_c is out of the hard bounds.
ATP:pyruvate O2-phosphotransferase Glycolysis / Gluconeogenesis / Purine metabolism / Pyruvate metabolism EC:2.7.1.40
3-Mercaptopyruvate:cyanide sulfurtransferase Cysteine metabolism EC:2.8.1.2
Warning: Species concentration Pyridoxamine-P_c is out of the soft bounds.
Malonyl-CoA carboxy-lyase beta-Alanine metabolism / Propanoate metabolism EC:4.1.1.9
Gentisate aldehyde:NAD+ oxidoreductase Tyrosine metabolism EC:1.2.1.29
Warning: Species concentration L-Carnitine_r is out of the soft bounds.
Error: Species concentration cis-Aconitate_m is out of the hard bounds.
Warning: Species concentration myristic-acid_s is out of the soft bounds.
Error: Species concentration sulfochenodeoxycholate_c is out of the hard bounds.
Error: Species concentration Alanine_s is out of the hard bounds.
Error: Species concentration CoA_r is out of the hard bounds.
Warning: Species concentration Dihydrothymine_m is out of the soft bounds.
Warning: Species concentration Pyridoxamine_s is out of the soft bounds.
Warning: Species concentration Cholesterol_r is out of the soft bounds.
ATP:AMP phosphotransferase Purine metabolism EC:2.7.4.3
Warning: Species concentration N-Methylethanolamine-P_c is out of the soft bounds.
Warning: Species concentration Phosphatidate-VLDL-PE-pool_c is out of the soft bounds.
Error: Species concentration 2-Oxobutyrate_c is out of the hard bounds.
Warning: Species concentration Collagen_FCN3_c is out of the soft bounds.
Warning: Species concentration 5,10-Methylene-THF_c is out of the soft bounds.
Warning: Species concentration prostaglandin-c2_s is out of the soft bounds.
Warning: Species concentration Glycochenodeoxycholate_c is out of the soft bounds.
Error: Species concentration NO_c is out of the hard bounds.
Error: Species concentration 3PG_c is out of the hard bounds.
Error: Species concentration Dihydrolipoamide_m is out of the hard bounds.
Warning: Species concentration Hexadecanal_c is out of the soft bounds.
Error: Species concentration 4alpha-Methylzymosterol-4-carboxylate_r is out of the hard bounds.
Warning: Species concentration L-Oleoylcarnitine_m is out of the soft bounds.
Warning: Species concentration Taurine_s is out of the soft bounds.
Error: Species concentration Formate_s is out of the hard bounds.
Error: Species concentration Palmitolate_c is out of the hard bounds.
Error: Species concentration Lepidimoide_s is out of the hard bounds.
Warning: Species concentration K+_s is out of the soft bounds.
Hypoxanthine:oxygen oxidoreductase Purine metabolism EC:1.17.3.2
Warning: Species concentration (R)-4-Phosphopantothenoyl-cysteine_c is out of the soft bounds.
Error: Species concentration Isomaltose_s is out of the hard bounds.
Error: Species concentration 3-Phosphoserine_c is out of the hard bounds.
Warning: Species concentration N-Acetyl-D-mannosamine_s is out of the soft bounds.
Warning: Species concentration NADPH_c is out of the soft bounds.
Error: Species concentration NADH-redox-potential_r is out of the hard bounds.
Error: Species concentration 10-Formyl-THF_m is out of the hard bounds.
CDP diphosphohydrolase Pyrimidine metabolism EC:3.6.1.5
Error: Species concentration decanoic-acid_c is out of the hard bounds.
Warning: Species concentration Glutamine_s is out of the soft bounds.
2-Methyl-3-oxopropanoate:NAD+ oxidoreductase (CoA-propanoylating) EC:1.2.1.27
Warning: Species concentration Inositol-1P_c is out of the soft bounds.
Warning: Species concentration UDP-galactose_c is out of the soft bounds.
Warning: Species concentration Bilirubin-bisglucuronoside_s is out of the soft bounds.
Error: Species concentration FAD_c is out of the hard bounds.
(3R)-3-Hydroxydodecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase Fatty acid biosynthesis EC:2.3.1.85
Error: Species concentration Inositol_r is out of the hard bounds.
3-Hydroxy-L-kynurenine hydrolase Tryptophan metabolism EC:3.7.1.3
Warning: Species concentration Deoxyadenosine_s is out of the soft bounds.
Error: Species concentration Hexanoyl-CoA_m is out of the hard bounds.
Error: Species concentration ITP_c is out of the hard bounds.
Warning: Species concentration CMP_r is out of the soft bounds.
Warning: Species concentration Hypoxanthine_s is out of the soft bounds.
Error: Species concentration 3-Hydroxyanthranilate_c is out of the hard bounds.
Warning: Species concentration Asparagine_s is out of the soft bounds.
Warning: Species concentration Fumarylacetoacetate_c is out of the soft bounds.
Warning: Species concentration ATP-energy_c is out of the soft bounds.
Error: Species concentration dAMP_c is out of the hard bounds.
Warning: Species concentration Sucrose_s is out of the soft bounds.
Cation Diffusion Facilitator (CDF) TCDB:2.A.4.2.3
Error: Species concentration CTP_c is out of the hard bounds.
Warning: Species concentration Oleoyl-CoA_r is out of the soft bounds.
Warning: Species concentration L-Carnitine_p is out of the soft bounds.
Warning: Species concentration Leucine_l is out of the soft bounds.
Warning: Species concentration L-2-Aminoadipate_c is out of the soft bounds.
Warning: Species concentration reverse-triiodthyronine_c is out of the soft bounds.
Warning: Species concentration Threonine_c is out of the soft bounds.
Error: Species concentration 1,2-Diacylglycerol-VLDL-SM-pool_c is out of the hard bounds.
Warning: Species concentration L-Lactate_p is out of the soft bounds.
Error: Species concentration Collagen_VWA2_c is out of the hard bounds.
Error: Species concentration Collagen_ADIPO_c is out of the hard bounds.
Error: Species concentration Lignocerate_s is out of the hard bounds.
Warning: Species concentration Oxalosuccinate_m is out of the soft bounds.
Collagen alpha-3(VI) chain Protein assembly
hexanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) Fatty acid biosynthesis EC:2.3.1.85
Acyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) Fatty acid biosynthesis EC:2.3.1.85
Error: Species concentration ApoC3_r is out of the hard bounds.
Warning: Species concentration 3-Oxodecanoyl-CoA_m is out of the soft bounds.
Error: Species concentration 5beta-Cholestane-3alpha,7alpha-diol_c is out of the hard bounds.
Error: Species concentration PNP_s is out of the hard bounds.
L-Leucine:2-oxoglutarate aminotransferase Valine, leucine and isoleucine degradation / Valine, leucine and isoleucine biosynthesis EC:2.6.1.42
Error: Species concentration Linoleoyl-CoA_p is out of the hard bounds.
ATP:inosine 5'-phosphotransferase Purine metabolism EC:2.7.1.73
Warning: Species concentration cis-Aconitate_m is out of the soft bounds.
Uroporphyrinogen I carboxy-lyase Porphyrin and chlorophyll metabolism EC:4.1.1.37
Error: Species concentration Orotidine-5P_c is out of the hard bounds.
Error: Species concentration CDP_m is out of the hard bounds.
Warning: Species concentration (S)-3-Hydroxytetradecanoyl-CoA_p is out of the soft bounds.
Warning: Species concentration (S)-Hydroxydecanoyl-CoA_p is out of the soft bounds.
Phsophatidyl-L-serine carboxy-lyase Glycine, serine and threonine metabolism / Glycerophospholipid metabolism EC:4.1.1.65
Phosphatidylglycerophosphate phosphohydrolase Glycerophospholipid metabolism EC:3.1.3.27
Error: Species concentration CMP-N-acetylneuraminate_c is out of the hard bounds.
Warning: Species concentration palmitoleoyl-Carnitine_c is out of the soft bounds.
Warning: Species concentration (S)-Hydroxyoctanoyl-CoA_m is out of the soft bounds.
(S)-3-Hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating) Synthesis and degradation of ketone bodies / Valine, leucine and isoleucine degradation / Butanoate metabolism EC:2.3.3.10
Warning: Species concentration S-glutathionyl-ethacrynic-acid_s is out of the soft bounds.
Error: Species concentration S-Acetyldihydrolipoamide_m is out of the hard bounds.
Warning: Species concentration N-Acetylneuraminate_n is out of the soft bounds.
Warning: Species concentration 1-Acylglycerol-3P-VLDL-SM-pool_c is out of the soft bounds.
Warning: Species concentration Formylglutathione_c is out of the soft bounds.
(S)-3-Hydroxyisobutyryl-CoA hydro-lyase Valine, leucine and isoleucine degradation EC:4.2.1.17
Error: Species concentration O-Propanoylcarnitine_m is out of the hard bounds.
Error: Species concentration Methylmalonyl-CoA_m is out of the hard bounds.
Sulfite:ferricytochrome-c oxidoreductase Sulfur metabolism EC:1.8.2.1
ATP:dTMP phosphotransferase Pyrimidine metabolism EC:2.7.4.12 EC:2.7.4.9
Warning: Species concentration N-Acetylneuraminate-9P_c is out of the soft bounds.
Warning: Species concentration NADH_r is out of the soft bounds.
Error: Species concentration ApoA1_c is out of the hard bounds.
2-Phospho-D-glucerate hydro-lyase Glycolysis / Gluconeogenesis EC:4.2.1.11
Warning: Species concentration Xanthosine_c is out of the soft bounds.
2'-Deoxyguanosine 5'-monophosphate phosphohydrolase Purine metabolism EC:3.1.3.5
Error: Species concentration mitoApo-ACP_m is out of the hard bounds.
Error: Species concentration Fatty-acid-VLDL-TG3-pool_c is out of the hard bounds.
Warning: Species concentration O2.-_s is out of the soft bounds.
Warning: Species concentration HMA_c is out of the soft bounds.
Warning: Species concentration Glycine_s is out of the soft bounds.
UTP:D-fructose-6-phosphate 1-phosphotransferase EC:2.7.1.11
Error: Species concentration Formate_m is out of the hard bounds.
N-Acetylneuraminate 9-phosphate phosphohydrolase Aminosugars metabolism EC:3.1.3.29
Error: Species concentration Zymosterol_r is out of the hard bounds.
Warning: Species concentration AMP_c is out of the soft bounds.
Warning: Species concentration Galactose-1P_c is out of the soft bounds.
Warning: Species concentration Mercaptopyruvate_c is out of the soft bounds.
Error: Species concentration NADH-redox-potential_c is out of the hard bounds.
Warning: Species concentration Methylglyoxal_c is out of the soft bounds.
Palmitoyl-CoA hydrolase Fatty acid elongation in mitochondria EC:3.1.2.22 EC:3.1.2.2
Warning: Species concentration Triiodothyronine_s is out of the soft bounds.
Warning: Species concentration 2,5-Dihydroxybenzoate_c is out of the soft bounds.
Error: Species concentration Glucosylceramide-pool_s is out of the hard bounds.
3alpha,7alpha-Dihydroxy-5beta-cholestane:NAD+ oxidoreductase (B-specific); 3alpha,7alpha-Dihydroxy-5beta-cholestane:NAD+ oxidoreductase Bile acid biosynthesis EC:1.1.1.50
Warning: Species concentration Phosphatidate-CL-pool_m is out of the soft bounds.
Error: Species concentration THF_m is out of the hard bounds.
Error: Species concentration 3-Oxodecanoyl-ACP_c is out of the hard bounds.
Error: Species concentration L-Formylkynurenine_c is out of the hard bounds.
Warning: Species concentration (2E)-Hexenoyl-ACP_c is out of the soft bounds.
Error: Species concentration Chenodeoxycholoyl-CoA_p is out of the hard bounds.
Warning: Species concentration CDP-ethanolamine_c is out of the soft bounds.
Warning: Species concentration 3-oxomyrist-7-enoyl-CoA_m is out of the soft bounds.
Collagen alpha-2(IV) chain Protein assembly
Warning: Species concentration Thymidine_m is out of the soft bounds.
Warning: Species concentration CMP_c is out of the soft bounds.
Error: Species concentration 3-Oxopalmitoyl-CoA_m is out of the hard bounds.
Warning: Species concentration 3-Carboxy-1-hydroxypropyl-ThPP_m is out of the soft bounds.
collagen, type IV, alpha 6 Protein assembly
Error: Species concentration VLDL_s is out of the hard bounds.
Error: Species concentration Xanthine_p is out of the hard bounds.
Error: Species concentration Glycogenin-G11_c is out of the hard bounds.
Warning: Species concentration Taurochenodeoxycholate_p is out of the soft bounds.
Error: Species concentration beta-Alanine_s is out of the hard bounds.
Warning: Species concentration Stearoyl-ACP_c is out of the soft bounds.
Error: Species concentration Mannose_s is out of the hard bounds.
Warning: Species concentration Ribose-5P_r is out of the soft bounds.
Warning: Species concentration Linoleoyl-CoA_p is out of the soft bounds.
Warning: Species concentration 7-Dehydrodesmosterol_r is out of the soft bounds.
3-Hydroxypropionyl-CoA hydro-lyase beta-Alanine metabolism / Propanoate metabolism EC:4.2.1.17
Warning: Species concentration Anthranilate_c is out of the soft bounds.
Error: Species concentration 6-Phospho-D-gluconate_c is out of the hard bounds.
Error: Species concentration Cholesterol-ester-lin_l is out of the hard bounds.
Warning: Species concentration O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine_c is out of the soft bounds.
Error: Species concentration ApoE_c is out of the hard bounds.
Error: Species concentration Oxalate_c is out of the hard bounds.
Warning: Species concentration S-glutathionyl-2-4-dinitrobenzene_c is out of the soft bounds.
2-Phospho-D-glycerate 2,3-phosphomutase Glycolysis / Gluconeogenesis EC:5.4.2.1
Warning: Species concentration Fructose_s is out of the soft bounds.
Warning: Species concentration Arginine_l is out of the soft bounds.
Warning: Species concentration Urocanate_c is out of the soft bounds.
Error: Species concentration Prothrombin_s is out of the hard bounds.
Warning: Species concentration NAD+_m is out of the soft bounds.
Warning: Species concentration N-Acetyl-D-mannosamine_r is out of the soft bounds.
Acetyl-CoA:acetyl-CoA C-acetyltransferase Synthesis and degradation of ketone bodies EC:2.3.1.9
Warning: Species concentration Lactose_s is out of the soft bounds.
(S)-Lactate:NAD+ oxidoreductase Glycolysis / Gluconeogenesis / Pyruvate metabolism EC:1.1.1.27
Warning: Species concentration Collagen_CO7A1_c is out of the soft bounds.
Error: Species concentration Thiamin-PP_m is out of the hard bounds.
Error: Species concentration N-Pantothenoylcysteine_m is out of the hard bounds.
Warning: Species concentration Citrate_m is out of the soft bounds.
Warning: Species concentration Bilirubin_c is out of the soft bounds.
Error: Species concentration N-Carbamoyl-L-aspartate_c is out of the hard bounds.
Error: Species concentration Acetate_c is out of the hard bounds.
Error: Species concentration Pyridoxal-P_s is out of the hard bounds.
Warning: Species concentration CDP-choline_c is out of the soft bounds.
Warning: Species concentration Glycine_l is out of the soft bounds.
Warning: Species concentration ApoC1_c is out of the soft bounds.
Error: Species concentration 3(S)-3-hydroxydodecen-(5Z)-oyl-CoA_m is out of the hard bounds.
Error: Species concentration 1-Acylglycerol-3P-Bile-PC-pool_c is out of the hard bounds.
Warning: Species concentration Fatty-acid-VLDL-PS-pool_c is out of the soft bounds.
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming) Bile acid biosynthesis EC:6.2.1.7
Error: Species concentration Cholesterol-ester-arach_l is out of the hard bounds.
Error: Species concentration 2-Methylacetoacetyl-CoA_m is out of the hard bounds.
Warning: Species concentration Dodecanoyl-ACP_c is out of the soft bounds.
(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA hydro-liase Valine, leucine and isoleucine degradation EC:4.2.1.17
Neurotransmitter:Sodium Symporter (NSS) TCDB:2.A.22.2.2
Warning: Species concentration Dihomo-gamma-linolenate_s is out of the soft bounds.
Error: Species concentration L-1-Pyrroline-3-hydroxy-5-carboxylate_c is out of the hard bounds.
Error: Species concentration LDL_l is out of the hard bounds.
Error: Species concentration 1-Acylglycerol-3P-VLDL-PE-pool_c is out of the hard bounds.
Warning: Species concentration NeuNGc_c is out of the soft bounds.
Error: Species concentration NADPH_p is out of the hard bounds.
Malonyl-CoA:[acyl-carrier-protein] S-malonyltransferase Fatty acid biosynthesis EC:2.3.1.85
Error: Species concentration K+_c is out of the hard bounds.
Error: Species concentration Propanoate_m is out of the hard bounds.
Error: Species concentration Ceramide-pool_c is out of the hard bounds.
CTP:ethanolamine-phosphate cytidylyltransferase Glycerophospholipid metabolism EC:2.7.7.14
Error: Species concentration Formamidopyrimidine_nleoside_triphosphate_c is out of the hard bounds.
Error: Species concentration L-Lactate_c is out of the hard bounds.
Error: Species concentration prostaglandin-a1_c is out of the hard bounds.
Warning: Species concentration leukotriene-a4_c is out of the soft bounds.
Error: Species concentration CDP-choline_r is out of the hard bounds.
L-1-Pyrroline-5-carboxylate:NAD+ oxidoreductase Glutamate metabolism / Arginine and proline metabolism EC:1.5.1.12
3,4-Dihydroxymandelaldehyde:NAD+ oxidoreductase Tyrosine metabolism EC:1.2.1.5
L-Arginine:glycine amidinotransferase Glycine, serine and threonine metabolism / Arginine and proline metabolism EC:2.1.4.1
Warning: Species concentration Collagen_PCOTH_c is out of the soft bounds.
Warning: Species concentration Glycerate_c is out of the soft bounds.
Warning: Species concentration Malonate_c is out of the soft bounds.
Warning: Species concentration prostaglandin-d1_c is out of the soft bounds.
Palmitate:CoA ligase (AMP-forming) Fatty acid metabolism EC:6.2.1.3
Error: Species concentration Ribose-1P_c is out of the hard bounds.
Error: Species concentration dGDP_m is out of the hard bounds.
Warning: Species concentration 2-Amino-3-oxoadipate_m is out of the soft bounds.
Warning: Species concentration CMP_n is out of the soft bounds.
L-aspartate:L-glutamine amido-ligase (AMP-forming) Alanine and aspartate metabolism / Nitrogen metabolism EC:6.3.5.4
Warning: Species concentration NAD+_c is out of the soft bounds.
Error: Species concentration Cytidine_c is out of the hard bounds.
Warning: Species concentration leukotriene-e4_s is out of the soft bounds.
Error: Species concentration GTP_m is out of the hard bounds.
Warning: Species concentration (R)-4-Phosphopantothenoyl-cysteine_m is out of the soft bounds.
Warning: Species concentration Collagen_COBA2_c is out of the soft bounds.
Error: Species concentration Creatine_c is out of the hard bounds.
Error: Species concentration OAA_m is out of the hard bounds.
Warning: Species concentration Cys-Gly_s is out of the soft bounds.
Error: Species concentration L-Carnitine_r is out of the hard bounds.
Warning: Species concentration UDP-activated-glucose_c is out of the soft bounds.
Error: Species concentration Collagen_CO1A1_c is out of the hard bounds.
Error: Species concentration AMP_c is out of the hard bounds.
Warning: Species concentration Homovanillate_m is out of the soft bounds.
Concentrative Nucleoside Transporter (CNT) TCDB:2.A.41.2.3
Error: Species concentration Collagen_FCN3_c is out of the hard bounds.
Error: Species concentration palmitoleoyl-Carnitine_c is out of the hard bounds.
Error: Species concentration Oxalosuccinate_c is out of the hard bounds.
dCDP nucleotidohydrolase Pyrimidine metabolism EC:3.6.1.12
Error: Species concentration H2O_r is out of the hard bounds.
Warning: Species concentration Chenodiol_r is out of the soft bounds.
Error: Species concentration 5,10-Methylene-THF_c is out of the hard bounds.
Warning: Species concentration Dihydrolipoamide_m is out of the soft bounds.
Warning: Species concentration Ascorbate_c is out of the soft bounds.
Error: Species concentration prostaglandin-c2_s is out of the hard bounds.
Error: Species concentration Glycochenodeoxycholate_c is out of the hard bounds.
Warning: Species concentration Phenylalanine_m is out of the soft bounds.
Error: Species concentration Pantetheine_m is out of the hard bounds.
Error: Species concentration Succinate_c is out of the hard bounds.
Warning: Species concentration H2O2_c is out of the soft bounds.
Warning: Species concentration 3alpha,7alpha-Dihydroxy-5beta-cholestanate_r is out of the soft bounds.
Error: Species concentration 1-Acylglycerol-3P-VLDL-SM-pool_c is out of the hard bounds.
Error: Species concentration myristic-acid_c is out of the hard bounds.
Error: Species concentration 2-Deoxy-D-ribose-1P_c is out of the hard bounds.
Error: Species concentration 2-Oxoadipate_c is out of the hard bounds.
dCMP aminohydrolase Pyrimidine metabolism EC:3.5.4.12
Warning: Species concentration O2_m is out of the soft bounds.
Error: Species concentration Dephospho-CoA_c is out of the hard bounds.
Error: Species concentration Taurine_s is out of the hard bounds.
Error: Species concentration Thymine_c is out of the hard bounds.
Warning: Species concentration Argininosuccinate_c is out of the soft bounds.
Error: Species concentration Ornithine_c is out of the hard bounds.
Warning: Species concentration 2-Hydroxybutyrate_c is out of the soft bounds.
Error: Species concentration GSSG_c is out of the hard bounds.
Full of fluid protein homolog Protein assembly
Warning: Species concentration Taurocholate_s is out of the soft bounds.
citrate hydro-lyase Citrate cycle (TCA cycle) EC:4.2.1.3
Error: Species concentration Cysteamine_c is out of the hard bounds.
Warning: Species concentration Deoxyuridine_c is out of the soft bounds.
Warning: Species concentration 4-Aminobutanal_m is out of the soft bounds.
Warning: Species concentration Fe2+_s is out of the soft bounds.
Error: Species concentration Fumarylacetoacetate_c is out of the hard bounds.
Warning: Species concentration NADP+_m is out of the soft bounds.
Warning: Species concentration VLDL_l is out of the soft bounds.
Error: Species concentration But-2-enoyl-ACP_c is out of the hard bounds.
Warning: Species concentration Butyryl-CoA_m is out of the soft bounds.
Warning: Species concentration D-3-Amino-isobutanoate_c is out of the soft bounds.
Warning: Species concentration Citrate_c is out of the soft bounds.
(3R)-3-Hydroxyhexanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase Fatty acid biosynthesis EC:2.3.1.85
collagen, type XVIII, alpha 1 Protein assembly
Warning: Species concentration Phosphatidate-VLDL-PI-pool_c is out of the soft bounds.
Warning: Species concentration ursodeoxycholate_c is out of the soft bounds.
Error: Species concentration UDP-galactose_c is out of the hard bounds.
sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) Biosynthesis of steroids EC:1.1.1.170
Error: Species concentration cis-laur-5-enoyl-CoA_m is out of the hard bounds.
Error: Species concentration Fatty-acid-VLDL-PC-pool_l is out of the hard bounds.
S-Aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming) One carbon pool by folate EC:2.1.2.10
5-Formiminotetrahydrofolate:L-glutamate N-formiminotransferase Histidine metabolism / One carbon pool by folate EC:2.1.2.5
Warning: Species concentration Histidine_c is out of the soft bounds.
Error: Species concentration GSH-potential_c is out of the hard bounds.
Error: Species concentration THF-activated_methyl_group_c is out of the hard bounds.
Error: Species concentration Oleoyl-CoA_r is out of the hard bounds.
Warning: Species concentration 5beta-Cholestane-3alpha,7alpha,26-triol_c is out of the soft bounds.
Error: Species concentration reverse-triiodthyronine_c is out of the hard bounds.
2-Methylpropanoyl-CoA:oxygen 2,3-oxidoreductase Valine, leucine and isoleucine degradation EC:1.3.99.2
5-Hydroxy-L-tryptophan decarboxy-lyase Tryptophan metabolism EC:4.1.1.28
Error: Species concentration Riboflavin_c is out of the hard bounds.
Warning: Species concentration sn-Glycerol-3P_m is out of the soft bounds.
Warning: Species concentration Collagen_SERPH_c is out of the soft bounds.
Error: Species concentration FADH-redox-potential_c is out of the hard bounds.
ATP:sphinganine 1-phosphotransferase Sphingolipid metabolism EC:2.7.1.91
Warning: Species concentration Tryptophan_c is out of the soft bounds.
Error: Species concentration Taurochenodeoxycholate_b is out of the hard bounds.
Error: Species concentration Histamine_b is out of the hard bounds.
Warning: Species concentration 5-Hydroxy-L-tryptophan_c is out of the soft bounds.
Warning: Species concentration Pantothenate_s is out of the soft bounds.
Warning: Species concentration leukotriene-b4_c is out of the soft bounds.
Warning: Species concentration Phosphatidate-VLDL-SM-pool_c is out of the soft bounds.
Error: Species concentration UDP_s is out of the hard bounds.
Warning: Species concentration Collagen_C43BP_c is out of the soft bounds.
1L-myo-Inositol-1-phosphate lyase (isomerizing) Streptomycin biosynthesis / Inositol phosphate metabolism EC:5.5.1.4
Warning: Species concentration Urea_c is out of the soft bounds.
Warning: Species concentration Collagen_COSA1_c is out of the soft bounds.
D-Ribose 1,5-phosphomutase Pentose phosphate pathway / Purine metabolism EC:5.4.2.2
Error: Species concentration Putrescine_s is out of the hard bounds.
Glycoside-Pentoside-Hexuronide (GPH):Cation Symporter TCDB:2.A.23.2.3
Warning: Species concentration N-Formyl-GAR_c is out of the soft bounds.
Error: Species concentration PRPP_s is out of the hard bounds.
Warning: Species concentration 5,10-Methenyl-THF_c is out of the soft bounds.
Error: Species concentration LTD4_c is out of the hard bounds.
Warning: Species concentration Propanoate_c is out of the soft bounds.
Error: Species concentration S-glutathionyl-ethacrynic-acid_s is out of the hard bounds.
Warning: Species concentration Phosphopantetheine_m is out of the soft bounds.
Error: Species concentration Oleoyl-CoA_m is out of the hard bounds.
Warning: Species concentration 2-Oxoglutaramate_c is out of the soft bounds.
Error: Species concentration 7alpha-Hydroxycholesterol_r is out of the hard bounds.
Warning: Species concentration 3-Phosphonooxypyruvate_c is out of the soft bounds.
Ethanolamine-phosphate phospho-lyase (deaminating) EC:4.2.3.2
(S)-Methylmalonyl-CoA hydrolase Propanoate metabolism EC:3.1.2.17
Error: Species concentration trans,cis-myristo-2,7-dienoyl-CoA_m is out of the hard bounds.
Error: Species concentration palmitoleoyl-CoA_r is out of the hard bounds.
NAD(P) dependent steroid dehydrogenase-like EC:1.1.1.170
Error: Species concentration Malonyl-CoA_m is out of the hard bounds.
Warning: Species concentration Retinoate_c is out of the soft bounds.
Warning: Species concentration H2O2_m is out of the soft bounds.
Warning: Species concentration glycolithocholate_c is out of the soft bounds.
Nicotinate D-ribonucleotide phosphohydrolase Nicotinate and nicotinamide metabolism EC:3.1.3.5
Error: Species concentration (S)-Hydroxyoctanoyl-CoA_m is out of the hard bounds.
Error: Species concentration 5beta-Cholestane-3alpha,7alpha-diol_m is out of the hard bounds.
(3R)-3-Hydroxydecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase Fatty acid biosynthesis EC:2.3.1.85
Warning: Species concentration Dihydrobiopterin_c is out of the soft bounds.
Warning: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al_c is out of the soft bounds.
Adenosine aminohydrolase Purine metabolism EC:3.5.4.4
Error: Species concentration ADP_r is out of the hard bounds.
Warning: Species concentration Xanthosine-5P_c is out of the soft bounds.
Error: Species concentration Methylglyoxal_c is out of the hard bounds.
Warning: Species concentration 5-Phosphoribosyl-4-carboxy-5-aminoimidazole_c is out of the soft bounds.
Error: Species concentration Acetyl_adenylate_c is out of the hard bounds.
Warning: Species concentration Collagen_CO4A6_c is out of the soft bounds.
Error: Species concentration (2E)-Hexadecenoyl-ACP_c is out of the hard bounds.
Warning: Species concentration taurolithocholate_s is out of the soft bounds.
Error: Species concentration Elaidate_c is out of the hard bounds.
Warning: Species concentration Glucosylceramide-pool_c is out of the soft bounds.
Warning: Species concentration Fatty-acid-VLDL-TG1-pool_c is out of the soft bounds.
Warning: Species concentration Glutamate_l is out of the soft bounds.
Warning: Species concentration (2E)-Dodecenoyl-ACP_c is out of the soft bounds.
Warning: Species concentration Lepidimoide_c is out of the soft bounds.
Warning: Species concentration linoleic-Carnitine_c is out of the soft bounds.
Propanoyl-CoA:carbon-dioxide ligase (ADP-forming) Valine, leucine and isoleucine degradation / Propanoate metabolism EC:6.4.1.3
Warning: Species concentration Succinate_semialdehyde_m is out of the soft bounds.
Warning: Species concentration 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al_c is out of the soft bounds.
Error: Species concentration dTMP_m is out of the hard bounds.
L-O-Phosphoserine phosphohydrolase Glycine, serine and threonine metabolism EC:3.1.3.3
N-((R)-Pantothenoyl)-L-cysteine carboxy-lyase Pantothenate and CoA biosynthesis EC:4.1.1.30
Error: Species concentration N-Acetylglucosamine-6P_c is out of the hard bounds.
Warning: Species concentration Pi_s is out of the soft bounds.
Error: Species concentration IDP_s is out of the hard bounds.
(S)-3-Hydroxytetradecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.35 EC:1.1.1.211
Warning: Species concentration D-3-Amino-isobutanoate_s is out of the soft bounds.
Error: Species concentration Phosphatidate-Bile-PC-pool_c is out of the hard bounds.
Warning: Species concentration O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine_s is out of the soft bounds.
3-methylbutanoyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-(3-methylbutanoyl)transferase Valine, leucine and isoleucine degradation EC:2.3.1.168
Error: Species concentration prostaglandin-a2_c is out of the hard bounds.
Error: Species concentration sulfotaurolithocholate_c is out of the hard bounds.
Warning: Species concentration (S)-3-Hydroxyhexadecanoyl-CoA_p is out of the soft bounds.
Warning: Species concentration H+(PG)_p is out of the soft bounds.
Error: Species concentration Octanoyl-CoA_m is out of the hard bounds.
Warning: Species concentration Formate_r is out of the soft bounds.
cytidine monophospho-N-acetylneuraminic acid hydroxylase EC:1.14.18.2
Isopentenyl-diphosphate delta3-delta2-isomerase Biosynthesis of steroids / Terpenoid biosynthesis EC:5.3.3.2
Error: Species concentration 7-Dehydrodesmosterol_r is out of the hard bounds.
Error: Species concentration 3-oxopalmitoleoyl-CoA_m is out of the hard bounds.
Error: Species concentration dGMP_s is out of the hard bounds.
Warning: Species concentration Linolenate_l is out of the soft bounds.
Warning: Species concentration (R)-3-Hydroxybutanoate_s is out of the soft bounds.
Warning: Species concentration 6-Phospho-D-gluconate_r is out of the soft bounds.
Warning: Species concentration Cholesterol-ester-lin_r is out of the soft bounds.
Error: Species concentration (2E)-Hexadecenoyl-CoA_m is out of the hard bounds.
Warning: Species concentration Proline_s is out of the soft bounds.
Warning: Species concentration L-2-Aminoadipate_m is out of the soft bounds.
Warning: Species concentration THF-activated_formyl_group_c is out of the soft bounds.
Error: Species concentration Xanthurenate_s is out of the hard bounds.
Warning: Species concentration GDP-L-fucose_c is out of the soft bounds.
Error: Species concentration S-Succinyldihydrolipoamide_m is out of the hard bounds.
Error: Species concentration Succinate_m is out of the hard bounds.
delta24-sterol reductase Biosynthesis of steroids EC:1.3.1.72
Error: Species concentration Lauroyl-CoA_m is out of the hard bounds.
Warning: Species concentration Noradrenaline_b is out of the soft bounds.
Warning: Species concentration Cholesterol_s is out of the soft bounds.
Warning: Species concentration Collagen_CODA1_c is out of the soft bounds.
Warning: Species concentration prostaglandin-h2_s is out of the soft bounds.
Warning: Species concentration 5-Methylthioadenosine_c is out of the soft bounds.
Warning: Species concentration NH3_m is out of the soft bounds.
Warning: Species concentration Collagen_COEA1_c is out of the soft bounds.
gamma-L-Glutamyl-L-cysteine:glycine ligase (ADP-forming) Glutamate metabolism / Glutathione metabolism EC:6.3.2.3
Warning: Species concentration Choloyl-CoA_p is out of the soft bounds.
Warning: Species concentration Acetoacetyl-CoA_m is out of the soft bounds.
Error: Species concentration PAP_c is out of the hard bounds.
Warning: Species concentration Arachidonate_s is out of the soft bounds.
Error: Species concentration 3-Keto-beta-D-galactose_s is out of the hard bounds.
Error: Species concentration Chenodiol_s is out of the hard bounds.
Warning: Species concentration Pyridoxal-P_c is out of the soft bounds.
Error: Species concentration GMP_s is out of the hard bounds.
Warning: Species concentration N-Pantothenoylcysteine_c is out of the soft bounds.
Warning: Species concentration Dehydroalanine_c is out of the soft bounds.
Error: Species concentration Phosphatidate-VLDL-TG-pool_c is out of the hard bounds.
ATP:dTMP phosphotransferase Pyrimidine metabolism EC:2.7.4.4
Error: Species concentration L-Carnitine_m is out of the hard bounds.
Warning: Species concentration cis-Aconitate_c is out of the soft bounds.
Warning: Species concentration prostaglandin-i2_s is out of the soft bounds.
Warning: Species concentration CoA_c is out of the soft bounds.
Error: Species concentration L-Lactate_m is out of the hard bounds.
Error: Species concentration Cholesterol_c is out of the hard bounds.
Error: Species concentration PS-VLDL-pool_b is out of the hard bounds.
Warning: Species concentration N-Acetylmannosamine-6P_c is out of the soft bounds.
Oxalosuccinate:NADP+ oxidoreductase (decarboxylating) Citrate cycle (TCA cycle) EC:1.1.1.42
Error: Species concentration Phosphatidate-VLDL-PI-pool_c is out of the hard bounds.
Error: Species concentration L-Octanoylcarnitine_p is out of the hard bounds.
hydrogen-peroxide:hydrogen-peroxide oxidoreductase EC:1.11.1.6
Error: Species concentration NeuNGc_c is out of the hard bounds.
2-Oxoadipate:lipoamde 2-oxidoreductase(decarboxylating and acceptor-succinylating) Tryptophan metabolism EC:1.2.4.2
Collagen alpha-1(XX) chain Protein assembly
Deoxyguanosine:orthophosphate ribosyltransferase Purine metabolism EC:2.4.2.1 EC:2.4.2.4
Warning: Species concentration ApoC1_r is out of the soft bounds.
Error: Species concentration Leukotriene_C4_c is out of the hard bounds.
Warning: Species concentration Glyceraldehyde_m is out of the soft bounds.
Warning: Species concentration Triacylglycerol-VLDL-pool_c is out of the soft bounds.
Error: Species concentration S-(3-Methylbutanoyl)-dihydrolipoamide_m is out of the hard bounds.
Error: Species concentration O2_r is out of the hard bounds.
Succinyl-CoA:glycine C-succinyl-transferase(decarboxylating) Glycine, serine and threonine metabolism / Porphyrin and chlorophyll metabolism EC:2.3.1.37
trans-Hex-2-enoyl-CoA reductase Fatty acid elongation in mitochondria EC:1.3.1.38
Adenosine 3',5'-phosphate 5'-nucleotidohydrolase Purine metabolism EC:3.1.4.17
Error: Species concentration N-Acetyl-D-mannosamine_s is out of the hard bounds.
Guanosine 5'-triphosphate pyrophosphohydrolase Purine metabolism EC:3.6.1.19
Warning: Species concentration ATP-energy_m is out of the soft bounds.
Putrescine:oxygen oxidoreductase (deaminating) Urea cycle and metabolism of amino groups EC:1.4.3.6
Long-chain carboxylate:CoA ligase (AMP-forming) EC:6.2.1.3
L-Glutamate 5-semialdehyde:NAD+ oxidoreductase Arginine and proline metabolism EC:1.5.1.12
L-Histidine carboxy-lyase Histidine metabolism EC:4.1.1.28
Warning: Species concentration Cholesterol-ester-gla_r is out of the soft bounds.
Porphobilinogen ammonia-lyase (polymerizing) Porphyrin and chlorophyll metabolism EC:2.5.1.61
Error: Species concentration 5-Methyl-THF_c is out of the hard bounds.
Error: Species concentration 3-Oxododecanoyl-CoA_m is out of the hard bounds.
D-Glucosamine-6-phosphate ketol-isomerase(deaminating) Aminosugars metabolism EC:3.5.99.6
Warning: Species concentration (R)-3-Hydroxybutanoyl-ACP_c is out of the soft bounds.
Error: Species concentration Mannose-6P_c is out of the hard bounds.
Warning: Species concentration Orotate_c is out of the soft bounds.
Warning: Species concentration Ribitol_s is out of the soft bounds.
Warning: Species concentration NADPH-redox-potential_r is out of the soft bounds.
Error: Species concentration Deoxyadenosine_s is out of the hard bounds.
Warning: Species concentration Uridine_s is out of the soft bounds.
Warning: Species concentration 3-Oxohexanoyl-CoA_m is out of the soft bounds.
CTP:phosphatidate cytidyltransferase Glycerophospholipid metabolism / Phosphatidylinositol signaling system EC:2.7.7.41
Error: Species concentration UDP-activated-glucose_c is out of the hard bounds.
Error: Species concentration 5alpha-Cholesta-7,24-dien-3beta-ol_r is out of the hard bounds.
Error: Species concentration Homoserine_s is out of the hard bounds.
Warning: Species concentration 1-Acylglycerol-3P-lin_c is out of the soft bounds.
(3R)-3-Hydroxybutanoyl-[acyl-carrier protein]:NADP+ oxidoreductase Fatty acid biosynthesis EC:2.3.1.85
Error: Species concentration Adenosylmethioninamine-potential_c is out of the hard bounds.
Warning: Species concentration Myristoyl-CoA_m is out of the soft bounds.
L-Arginine carboxy-lyase Urea cycle and metabolism of amino groups EC:4.1.1.19
Error: Species concentration Homovanillate_m is out of the hard bounds.
Warning: Species concentration 2PG_c is out of the soft bounds.
Agmatine amidinohydrolase Urea cycle and metabolism of amino groups EC:3.5.3.11
Error: Species concentration Asparagine_m is out of the hard bounds.
Error: Species concentration UMP_r is out of the hard bounds.
Warning: Species concentration 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA_r is out of the soft bounds.
Error: Species concentration Chenodiol_r is out of the hard bounds.
Error: Species concentration Deoxyguanosine_s is out of the hard bounds.
Error: Species concentration L-2-Aminoadipate_c is out of the hard bounds.
5alpha-cholest-7-en-3beta-ol, NADPH:oxygen 5-oxidoreductase Biosynthesis of steroids EC:1.14.21.6
Warning: Species concentration Antitrypsin_c is out of the soft bounds.
Error: Species concentration Threonine_c is out of the hard bounds.
Error: Species concentration 3alpha,7alpha-Dihydroxy-5beta-cholestanate_r is out of the hard bounds.
Error: Species concentration UDP-xylose_c is out of the hard bounds.
Error: Species concentration dUDP_c is out of the hard bounds.
(5-L-Glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing) Glutathione metabolism EC:2.3.2.4
Warning: Species concentration Sphingosine_c is out of the soft bounds.
Warning: Species concentration 3(S)-3-hydroxydodecen-(5Z)-oyl-CoA_m is out of the soft bounds.
Error: Species concentration 3-Carboxy-1-hydroxypropyl-ThPP_m is out of the hard bounds.
Warning: Species concentration cis-myrist-7-enoyl-CoA_m is out of the soft bounds.
Xanthosine 5'-phosphate phosphohydrolase Purine metabolism EC:3.1.3.5
Warning: Species concentration 4alpha-Methylzymosterol_r is out of the soft bounds.
Error: Species concentration Triiodothyronine_c is out of the hard bounds.
Carbamoyl-phosphate:L-ornithine carbamoyltransferase Urea cycle and metabolism of amino groups / Arginine and proline metabolism EC:2.1.3.3
ATP:D-fructose 1-phosphotransferase Fructose and mannose metabolism EC:2.7.1.3
(R)-pantetheine amidohydrolase Pantothenate and CoA biosynthesis EC:3.5.1.-
Warning: Species concentration ADP_l is out of the soft bounds.
Warning: Species concentration Linoleoyl-CoA_c is out of the soft bounds.
Error: Species concentration Linolenoyl-CoA_c is out of the hard bounds.
Error: Species concentration S-(2-Methylpropanoyl)-dihydrolipoamide_m is out of the hard bounds.
Warning: Species concentration Albumin_s is out of the soft bounds.
Error: Species concentration Fe2+_s is out of the hard bounds.
Error: Species concentration NADP+_m is out of the hard bounds.
Error: Species concentration Linolenoyl-CoA_r is out of the hard bounds.
alpha-Aminobutyryl histidine hydrolase Urea cycle and metabolism of amino groups EC:3.4.13.3
glycine synthase Nitrogen metabolism EC:2.1.2.10
Na(+)/bile acid cotransporter Active transport
Error: Species concentration D-3-Amino-isobutanoate_c is out of the hard bounds.
Warning: Species concentration Chitobiose_s is out of the soft bounds.
Error: Species concentration Aspartate_l is out of the hard bounds.
Warning: Species concentration GSSG_m is out of the soft bounds.
D-Ribulose-5-phosphate 3-epimerase Pentose phosphate pathway EC:5.1.3.1
Warning: Species concentration N-Acetylglucosamine_c is out of the soft bounds.
Collagen alpha-1(XXIII) chain Protein assembly
Error: Species concentration ursodeoxycholate_c is out of the hard bounds.
Error: Species concentration Taurochenodeoxycholate_s is out of the hard bounds.
Error: Species concentration 5-Hydroxyindoleacetaldehyde_c is out of the hard bounds.
Error: Species concentration Histidine_c is out of the hard bounds.
Warning: Species concentration Methionine_s is out of the soft bounds.
Error: Species concentration N-Acetylneuraminate_n is out of the hard bounds.
Error: Species concentration THF-hexaglutamate_c is out of the hard bounds.
Warning: Species concentration O-Propanoylcarnitine_c is out of the soft bounds.
Error: Species concentration Stearoyl-CoA_c is out of the hard bounds.
Warning: Species concentration Pi_c is out of the soft bounds.
Warning: Species concentration 2-Deoxy-D-ribose-5P_c is out of the soft bounds.
Warning: Species concentration HCO3-_b is out of the soft bounds.
Triphosphate phosphohydrolase EC:3.6.1.25
Error: Species concentration Acyl-CoA-CL-pool_m is out of the hard bounds.
Warning: Species concentration ApoA1_s is out of the soft bounds.
Warning: Species concentration Folate_c is out of the soft bounds.
Error: Species concentration lithocholate_s is out of the hard bounds.
Warning: Species concentration Aspartate_l is out of the soft bounds.
Warning: Species concentration 2-Lysolecithin-pool_l is out of the soft bounds.
Warning: Species concentration mitoACP_m is out of the soft bounds.
Warning: Species concentration Triacylglycerol-VLDL-pool_l is out of the soft bounds.
Warning: Species concentration dADP_m is out of the soft bounds.
Warning: Species concentration PPi_s is out of the soft bounds.
Error: Species concentration Dodecanoyl-ACP_c is out of the hard bounds.
Warning: Species concentration L-Xylulose_c is out of the soft bounds.
Error: Species concentration Glycine_s is out of the hard bounds.
Error: Species concentration HMA_c is out of the hard bounds.
Warning: Species concentration UDP-activated-glucuronate_c is out of the soft bounds.
Error: Species concentration Galactose-1P_c is out of the hard bounds.
Error: Species concentration Ferrocytochrome_b5_c is out of the hard bounds.
(3R)-3-Hydroxyoctanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase Fatty acid biosynthesis EC:2.3.1.85
Error: Species concentration Urea_c is out of the hard bounds.
Error: Species concentration (R)-3-Hydroxypalmitoyl-ACP_c is out of the hard bounds.
GTP:pyruvate O2-phosphotransferase Purine metabolism EC:2.7.1.40
Error: Species concentration Noradrenaline_b is out of the hard bounds.
ATP:choline phosphotransferase Glycerophospholipid metabolism EC:2.7.1.32
ATP:NAD+ 2'-phosphotransferase Nicotinate and nicotinamide metabolism EC:2.7.1.23
Warning: Species concentration Chenodeoxycholoyl-CoA_c is out of the soft bounds.
Error: Species concentration 5,10-Methenyl-THF_c is out of the hard bounds.
Warning: Species concentration Oleoyl-CoA_c is out of the soft bounds.
Warning: Species concentration Tyrosine_c is out of the soft bounds.
sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae) Biosynthesis of steroids EC:1.14.21.6
Warning: Species concentration IMP_s is out of the soft bounds.
Error: Species concentration CMP_m is out of the hard bounds.
Error: Species concentration Lepidimoide_c is out of the hard bounds.
Error: Species concentration dTDP_c is out of the hard bounds.
Warning: Species concentration Carnosine_c is out of the soft bounds.
Warning: Species concentration Glycogenin-G8_c is out of the soft bounds.
Thymidine:orthophosphate deoxyribosyltransferase Pyrimidine metabolism EC:2.4.2.4
Error: Species concentration UDP-N-acetylglucosamine_c is out of the hard bounds.
Error: Species concentration Stearoyl-ACP_c is out of the hard bounds.
Warning: Species concentration GM4-pool_s is out of the soft bounds.
Warning: Species concentration 5-Aminolevulinate_c is out of the soft bounds.
Warning: Species concentration Mannose_c is out of the soft bounds.
Error: Species concentration Apo-ACP_c is out of the hard bounds.
Warning: Species concentration leukotriene-e4_c is out of the soft bounds.
Error: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al_c is out of the hard bounds.
(S)-Hydroxyoctanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.211
Warning: Species concentration tauroursodeoxycholate_s is out of the soft bounds.
Error: Species concentration O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine_c is out of the hard bounds.
Error: Species concentration Adenine_c is out of the hard bounds.
Warning: Species concentration Cholesterol-ester-palmn_r is out of the soft bounds.
Warning: Species concentration Antichymotrypsin_c is out of the soft bounds.
Error: Species concentration Taurocholate_p is out of the hard bounds.
Warning: Species concentration 3-Oxohexadecanoyl-ACP_c is out of the soft bounds.
Error: Species concentration Fructose_s is out of the hard bounds.
Error: Species concentration Glyceraldehyde_m is out of the hard bounds.
Collagen alpha-1(XXII) chain Protein assembly
Error: Species concentration NAD+_r is out of the hard bounds.
Error: Species concentration Glutamate_l is out of the hard bounds.
Warning: Species concentration CoA_p is out of the soft bounds.
Error: Species concentration Lactose_s is out of the hard bounds.
Warning: Species concentration 2-Lysolecithin-pool_r is out of the soft bounds.
Error: Species concentration Thymine_s is out of the hard bounds.
Warning: Species concentration D-3-Hydroxydodecanoyl-ACP_c is out of the soft bounds.
D-Glucosyl-N-acylsphingosine glucohydrolase Sphingolipid metabolism EC:3.2.1.45
5,6,7,8-Tetrahydrofolate:NAD+ oxidoreductase One carbon pool by folate EC:1.5.1.3
Error: Species concentration Oleate_c is out of the hard bounds.
Error: Species concentration Alanine_c is out of the hard bounds.
Warning: Species concentration CO2_p is out of the soft bounds.
Error: Species concentration tauroursodeoxycholate_c is out of the hard bounds.
Error: Species concentration Fibrinogen_s is out of the hard bounds.
Error: Species concentration ApoC2_c is out of the hard bounds.
Warning: Species concentration Malonyl-CoA_p is out of the soft bounds.
Error: Species concentration Fatty-acid-VLDL-PS-pool_c is out of the hard bounds.
Error: Species concentration AKG_p is out of the hard bounds.
Warning: Species concentration Carbamoyl-P_c is out of the soft bounds.
Warning: Species concentration Glutamyl-5P_m is out of the soft bounds.
Warning: Species concentration sulfoglycolithocholate_s is out of the soft bounds.
Warning: Species concentration Deoxyadenosine_c is out of the soft bounds.
Error: Species concentration (S)-3-Hydroxyhexadecanoyl-CoA_p is out of the hard bounds.
isocitrate hydro-lyase Citrate cycle (TCA cycle) / Glyoxylate and dicarboxylate metabolism EC:4.2.1.3
Warning: Species concentration ATP_m is out of the soft bounds.
Warning: Species concentration S-Adenosylmethioninamine_c is out of the soft bounds.
Error: Species concentration Pi_m is out of the hard bounds.
Warning: Species concentration LDL_s is out of the soft bounds.
Warning: Species concentration Glycogenin-G7_c is out of the soft bounds.
Error: Species concentration Acetyl-ACP_c is out of the hard bounds.
Error: Species concentration Formate_r is out of the hard bounds.
Error: Species concentration Ubiquinone_m is out of the hard bounds.
Warning: Species concentration Guanine_c is out of the soft bounds.
Warning: Species concentration dGMP_c is out of the soft bounds.
Error: Species concentration (R)-3-Hydroxybutanoate_s is out of the hard bounds.
Warning: Species concentration Ceramide-pool_r is out of the soft bounds.
Warning: Species concentration Propanoyl-CoA_p is out of the soft bounds.
Warning: Species concentration PPi_n is out of the soft bounds.
Error: Species concentration Zinc_c is out of the hard bounds.
Warning: Species concentration gamma-Glutamyl-3-aminopropiononitrile_s is out of the soft bounds.
Warning: Species concentration 3PG_c is out of the soft bounds.
pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating) EC:1.2.4.1
L-Glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylationg) Urea cycle and metabolism of amino groups EC:1.2.1.41
Error: Species concentration Taurocholate_c is out of the hard bounds.
Error: Species concentration GDP-L-fucose_c is out of the hard bounds.
Error: Species concentration Hypotaurine_c is out of the hard bounds.
Warning: Species concentration Collagen_CONA1_c is out of the soft bounds.
Warning: Species concentration Creatine_s is out of the soft bounds.
Error: Species concentration DHAP_p is out of the hard bounds.
Warning: Species concentration Lignocerate_c is out of the soft bounds.
Error: Species concentration Cholesterol_s is out of the hard bounds.
Error: Species concentration Sulfate_c is out of the hard bounds.
Warning: Species concentration palmitoleoyl-CoA_m is out of the soft bounds.
Error: Species concentration Malonate_c is out of the hard bounds.
Error: Species concentration Serine_c is out of the hard bounds.
Error: Species concentration prostaglandin-d2_c is out of the hard bounds.
Error: Species concentration Asparagine_c is out of the hard bounds.
Warning: Species concentration Collagen_SCRB1_c is out of the soft bounds.
Error: Species concentration Glycogenin-G7G1_c is out of the hard bounds.
Warning: Species concentration Guanosine_s is out of the soft bounds.
Error: Species concentration 5-Oxoproline_c is out of the hard bounds.
Warning: Species concentration Chenodiol_c is out of the soft bounds.
Warning: Species concentration 5-Formyl-THF_m is out of the soft bounds.
Warning: Species concentration Lysine_m is out of the soft bounds.
Error: Species concentration Threonine_m is out of the hard bounds.
Error: Species concentration Cys-Gly_s is out of the hard bounds.
Warning: Species concentration L-Carnitine_c is out of the soft bounds.
Nucleobase:Cation Symporter-2 (NCS2) TCDB:2.A.40.6.2
trans-Dodec-2-enoyl-CoA reductase Fatty acid elongation in mitochondria EC:1.3.1.38
collagen, type IX, alpha 1 Protein assembly
ATP:ceramide 1-phosphotransferase Sphingolipid metabolism EC:2.7.1.138
Acyl-CoA:sphingosine N-acyltransferase Sphingolipid metabolism EC:2.3.1.24
Error: Species concentration dTDP_s is out of the hard bounds.
Warning: Species concentration palmitoleoyl-Carnitine_r is out of the soft bounds.
Warning: Species concentration H2O_c is out of the soft bounds.
Error: Species concentration ATP-energy_m is out of the hard bounds.
Warning: Species concentration CTP_s is out of the soft bounds.
Warning: Species concentration Urate_c is out of the soft bounds.
Warning: Species concentration 4-Maleylacetoacetate_c is out of the soft bounds.
Warning: Species concentration prostaglandin-c1_c is out of the soft bounds.
Error: Species concentration prostaglandin-b1_c is out of the hard bounds.
Error: Species concentration H2O2_c is out of the hard bounds.
Warning: Species concentration UroporphyrinogenI_s is out of the soft bounds.
Error: Species concentration Histidine_m is out of the hard bounds.
Warning: Species concentration 1-Acylglycerol-3P-VLDL-PI-pool_c is out of the soft bounds.
Divalent Anion:Na$^{+}$ Symporter (DASS) TCDB:2.A.47.1.9
Warning: Species concentration CO2_b is out of the soft bounds.
4-Nitrophenyl phosphate phosphohydrolase gamma-Hexachlorocyclohexane degradation EC:3.1.3.2 EC:3.1.3.41 EC:3.1.3.1
Warning: Species concentration lauric-acid_s is out of the soft bounds.
Warning: Species concentration NADP+_p is out of the soft bounds.
Error: Species concentration Argininosuccinate_c is out of the hard bounds.
Error: Species concentration Collagen_COBA2_c is out of the hard bounds.
Warning: Species concentration PC-VLDL-pool_l is out of the soft bounds.
5beta-cholestane-3alpha,7alpha-diol,NADPH:oxygen oxidoreductase (26-hydroxylating) Bile acid biosynthesis EC:1.14.13.15
Drug/Metabolite Transporter (DMT) TCDB:2.A.7.12.6
(S)-Methylmalonate semialdehyde:oxygen oxidoreductase Valine, leucine and isoleucine degradation EC:1.2.3.1
IDP diphosphohydrolase Purine metabolism EC:3.6.1.6
Warning: Species concentration Ferrocytochrome_C_m is out of the soft bounds.
methylsterol monooxygenase Biosynthesis of steroids EC:1.14.13.72
(S)-Malate hydro-lyase Citrate cycle (TCA cycle) EC:4.2.1.2
(S)-Hydroxydecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.211 EC:1.1.1.35
Warning: Species concentration Isocitrate_p is out of the soft bounds.
Error: Species concentration Cholesterol-ester-gla_r is out of the hard bounds.
Warning: Species concentration (S)-3-Hydroxydodecanoyl-CoA_p is out of the soft bounds.
Warning: Species concentration Squalene_2,3-oxide_r is out of the soft bounds.
Warning: Species concentration Fructose-2,6PP_c is out of the soft bounds.
Error: Species concentration Citrate_m is out of the hard bounds.
Error: Species concentration Myristoyl-CoA_m is out of the hard bounds.
Pyridoxamine:oxygen oxidoreductase (deaminating) Vitamin B6 metabolism EC:1.4.3.5
Warning: Species concentration UDP-galactose_r is out of the soft bounds.
Warning: Species concentration 3-oxolaur-cis-5-enoyl-CoA_m is out of the soft bounds.
Error: Species concentration mitoThioredoxin_m is out of the hard bounds.
Error: Species concentration 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA_r is out of the hard bounds.
Error: Species concentration Acetone_m is out of the hard bounds.
fatty acid desaturase Sphingolipid metabolism EC:1.14.-.-
Error: Species concentration Linoleate_r is out of the hard bounds.
Warning: Species concentration Deoxyguanosine_c is out of the soft bounds.
Error: Species concentration Thymidine_m is out of the hard bounds.
Error: Species concentration UDP-glucuronate_r is out of the hard bounds.
ATP:uridine 5'-phosphotransferase Pyrimidine metabolism EC:2.7.1.48
Warning: Species concentration UDP-xylose_r is out of the soft bounds.
Warning: Species concentration linoleic-Carnitine_p is out of the soft bounds.
Warning: Species concentration Riboflavin_s is out of the soft bounds.
Warning: Species concentration 1-Acylglycerol-3P-stea_c is out of the soft bounds.
Error: Species concentration Estrone_3-sulfate_s is out of the hard bounds.
5-Oxoproline amidohydrolase (ATP-hydrolysing) Glutathione metabolism EC:3.5.2.9
Palmitoyl-CoA:oxygen 2-oxidoreductase Fatty acid metabolism EC:1.3.3.6 EC:1.3.99.3
UDPglucose pyrophosphohydrolase Pyrimidine metabolism / Starch and sucrose metabolism EC:3.6.1.45
Warning: Species concentration Proline_m is out of the soft bounds.
D-Glyceraldehyde-3-phosphate:NAD+ oxidoreductase(phosphorylating) Glycolysis / Gluconeogenesis EC:1.2.1.12
Warning: Species concentration prostaglandin-e2_s is out of the soft bounds.
Error: Species concentration 4alpha-Methylzymosterol_r is out of the hard bounds.
Warning: Species concentration Acyl-CoA-VLDL-PS-pool_c is out of the soft bounds.
Warning: Species concentration 1-Acylglycerol-VLDL-PS-pool_c is out of the soft bounds.
Error: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanate_c is out of the hard bounds.
Warning: Species concentration Citrulline_s is out of the soft bounds.
Error: Species concentration ADP_l is out of the hard bounds.
Warning: Species concentration 2,5-Diaminopyrimidine_nleoside_triphosphate_c is out of the soft bounds.
Formamidopyrimidine nucleoside triphosphate 7,8-8,9-dihydrolase Folate biosynthesis EC:3.5.4.16
Error: Species concentration Dopamine_b is out of the hard bounds.
UDPglucose:N-acylsphingosine D-glucosyltransferase Sphingolipid metabolism EC:2.4.1.80
Warning: Species concentration Putrescine_c is out of the soft bounds.
IMP:pyrophosphate phosphoribosyltransferase Purine metabolism EC:2.4.2.8
ATP:D-ribose 5-phosphotransferase Pentose phosphate pathway EC:2.7.1.15
N-Acetyl-D-glucosamine-6-phosphate amidohydrolase Aminosugars metabolism EC:3.5.1.25
Warning: Species concentration Glucose-1P_c is out of the soft bounds.
Warning: Species concentration L-Octanoylcarnitine_c is out of the soft bounds.
Error: Species concentration N-Acetylglucosamine_c is out of the hard bounds.
pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating) Complex of EC:1.2.4.1 EC:2.3.1.12 EC:1.8.1.4
Warning: Species concentration Fumarate_m is out of the soft bounds.
Error: Species concentration Propanoate_c is out of the hard bounds.
Error: Species concentration Ascorbate_s is out of the hard bounds.
Warning: Species concentration D-4-Phosphopantothenate_c is out of the soft bounds.
CDPcholine:1,2-diacylglycerol cholinephosphotransferase Glycerophospholipid metabolism EC:2.7.8.2
2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate phosphohydrolase (alkaline optimum) Folate biosynthesis EC:3.1.3.1
ATP:deoxycitidine 5'-phosphotransferase Pyrimidine metabolism EC:2.7.1.74
Warning: Species concentration trans,cis-dodeca-2,5-dienoyl-CoA_m is out of the soft bounds.
Warning: Species concentration palmitoleoyl-CoA_c is out of the soft bounds.
Warning: Species concentration Fatty-acid-VLDL-SM-pool_c is out of the soft bounds.
Error: Species concentration Geranyl-PP_p is out of the hard bounds.
Warning: Species concentration Acyl-CoA-CL-pool_c is out of the soft bounds.
Error: Species concentration Folate_c is out of the hard bounds.
Warning: Species concentration lithocholate_c is out of the soft bounds.
3-Hydroxy-L-kynurenine:2-oxoglutarate aminotransferase Tryptophan metabolism EC:2.6.1.7
Error: Species concentration 2-Lysolecithin-pool_l is out of the hard bounds.
Error: Species concentration dADP_m is out of the hard bounds.
Warning: Species concentration Taurocholate_p is out of the soft bounds.
Error: Species concentration Arachidonyl-Carnitine_r is out of the hard bounds.
Warning: Species concentration 1-Acylglycerol-3P-VLDL-PC-pool_c is out of the soft bounds.
N-(L-Argininosuccinate) arginie-lyase Urea cycle and metabolism of amino groups / Alanine and aspartate metabolism / Arginine and proline metabolism EC:4.3.2.1
5,10-Methylenetetrahydrofolate:dUMP C-methyltransferase Pyrimidine metabolism / One carbon pool by folate EC:2.1.1.45
Error: Species concentration Plasminogen_l is out of the hard bounds.
Warning: Species concentration Palmitolate_l is out of the soft bounds.
2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate 7,8-8,9-dihydrolase Folate biosynthesis EC:3.5.4.16
L-Cysteine:2-oxoglutarate aminotransferase Cysteine metabolism EC:2.6.1.3
Error: Species concentration Xanthosine-5P_c is out of the hard bounds.
Error: Species concentration 5-Phosphoribosyl-4-carboxy-5-aminoimidazole_c is out of the hard bounds.
Error: Species concentration Collagen_CO4A6_c is out of the hard bounds.
Orotidine-5'-phosphate carboxy-lyase Pyrimidine metabolism EC:4.1.1.23
Warning: Species concentration Elaidate_s is out of the soft bounds.
Warning: Species concentration S-(2-Methylbutanoyl)-dihydrolipoamide_m is out of the soft bounds.
2-Amino-3-carboxymuconate semialdehyde carboxy-lyase Tryptophan metabolism EC:4.1.1.45
Warning: Species concentration Betaine_c is out of the soft bounds.
Error: Species concentration Haptoglobin_s is out of the hard bounds.
Warning: Species concentration Tryptophan_s is out of the soft bounds.
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al:NAD+ 26-oxidoreductase Bile acid biosynthesis EC:1.2.1.40
Error: Species concentration Ascorbate_c is out of the hard bounds.
Warning: Species concentration GM4-pool_c is out of the soft bounds.
Warning: Species concentration O-Butanoylcarnitine_c is out of the soft bounds.
Mitochondrial Carrier (MC) TCDB:2.A.29.2.1
Warning: Species concentration Chloride_s is out of the soft bounds.
Warning: Species concentration 5-Methyl-THF_c is out of the soft bounds.
Warning: Species concentration IDP_c is out of the soft bounds.
S-Adenosyl-L-methionine carboxy-lyase Urea cycle and metabolism of amino groups / Methionine metabolism EC:4.1.1.50
CTP:pyruvate O2-phosphotransferase EC:2.7.1.40
Xanthosine:orthophosphate ribosyltransferase Purine metabolism EC:2.4.2.1
collagen, type IV, alpha 3 Protein assembly
Warning: Species concentration Mannose-6P_c is out of the soft bounds.
Warning: Species concentration Deoxyuridine_s is out of the soft bounds.
Warning: Species concentration sulfotaurolithocholate_s is out of the soft bounds.
CTP:choline-phosphate cytidylyltransferase Glycerophospholipid metabolism EC:2.7.7.15
Error: Species concentration Acetylcholine_b is out of the hard bounds.
Warning: Species concentration VLDL_r is out of the soft bounds.
Error: Species concentration 3-Hydroxyisobutyryl-CoA_m is out of the hard bounds.
Error: Species concentration Proline_s is out of the hard bounds.
Error: Species concentration tauroursodeoxycholate_s is out of the hard bounds.
Error: Species concentration Propanoyl-CoA_m is out of the hard bounds.
Error: Species concentration L-2-Aminoadipate_m is out of the hard bounds.
Warning: Species concentration GMP_m is out of the soft bounds.
Error: Species concentration THF-activated_formyl_group_c is out of the hard bounds.
Warning: Species concentration Fructose_c is out of the soft bounds.
L-Cysteine L-homocysteine-lyase (deaminating) Cysteine metabolism EC:4.4.1.1
Warning: Species concentration UDP-N-acetylglucosamine_r is out of the soft bounds.
Error: Species concentration Noradrenaline_s is out of the hard bounds.
L-Cysteine:oxygen oxidoreductase Cysteine metabolism / Taurine and hypotaurine metabolism EC:1.13.11.20
CTP:D-Tagatose 6-phosphate 1-phosphotransferase Galactose metabolism EC:2.7.1.11
Warning: Species concentration thromboxane-b2_c is out of the soft bounds.
Error: Species concentration 5-Methylthioadenosine_c is out of the hard bounds.
Error: Species concentration CoA_p is out of the hard bounds.
Warning: Species concentration Ornithine_s is out of the soft bounds.
Error: Species concentration NH3_m is out of the hard bounds.
Warning: Species concentration decanoic-acid_s is out of the soft bounds.
Warning: Species concentration Phosphatidate-VLDL-PC-pool_c is out of the soft bounds.
Error: Species concentration Squalene_r is out of the hard bounds.
Error: Species concentration 2-Lysolecithin-pool_r is out of the hard bounds.
Warning: Species concentration (S)-Hydroxydecanoyl-CoA_m is out of the soft bounds.
Warning: Species concentration Bilirubin_r is out of the soft bounds.
6-Lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase Folate biosynthesis EC:1.1.1.220
Acetoacetate carboxy-lyase Synthesis and degradation of ketone bodies / Propanoate metabolism EC:4.1.1.4
Error: Species concentration D-3-Hydroxydodecanoyl-ACP_c is out of the hard bounds.
3-sn-phosphatidate phosphohydrolase Sphingolipid metabolism EC:3.1.3.4
Error: Species concentration Palmitoyl-CoA_p is out of the hard bounds.
Warning: Species concentration GMP_c is out of the soft bounds.
Warning: Species concentration Phenylacetaldehyde_c is out of the soft bounds.
Warning: Species concentration Cysteine_l is out of the soft bounds.
Warning: Species concentration Plasminogen_l is out of the soft bounds.
Warning: Species concentration Fibrinogen_c is out of the soft bounds.
Error: Species concentration N-Pantothenoylcysteine_c is out of the hard bounds.
Error: Species concentration Malonyl-CoA_p is out of the hard bounds.
Warning: Species concentration 2-Methyl-3-oxopropanoate_c is out of the soft bounds.
Warning: Species concentration GM2-pool_s is out of the soft bounds.
Warning: Species concentration 20-hydroxy-arachidonate_c is out of the soft bounds.
Warning: Species concentration Albumin_l is out of the soft bounds.
Error: Species concentration Alanine_l is out of the hard bounds.
Error: Species concentration CoA_c is out of the hard bounds.
Warning: Species concentration Triphosphate_c is out of the soft bounds.
Error: Species concentration 2-Oxoglutaramate_c is out of the hard bounds.
Warning: Species concentration Cholesterol_b is out of the soft bounds.
Warning: Species concentration (R)-Methylmalonyl-CoA_m is out of the soft bounds.
Error: Species concentration S-Adenosylmethioninamine_c is out of the hard bounds.
Error: Species concentration O2_c is out of the hard bounds.
Warning: Species concentration Phosphatidate-VLDL-PS-pool_c is out of the soft bounds.
Warning: Species concentration PS-VLDL-pool_r is out of the soft bounds.
Warning: Species concentration Pi_l is out of the soft bounds.
Error: Species concentration lauric-acid_c is out of the hard bounds.
Error: Species concentration (S)-3-hydroxypalmitoleoyl-CoA_m is out of the hard bounds.
Warning: Species concentration Linolenate_c is out of the soft bounds.
Warning: Species concentration Glycochenodeoxycholate_s is out of the soft bounds.
Warning: Species concentration Oleate_c is out of the soft bounds.
Error: Species concentration H+(PG)_c is out of the hard bounds.
Error: Species concentration ApoC1_r is out of the hard bounds.
Error: Species concentration Tyrosine_l is out of the hard bounds.
Warning: Species concentration Acetylcholine_s is out of the soft bounds.
Error: Species concentration 3-Oxotetradecanoyl-CoA_p is out of the hard bounds.
Error: Species concentration Ethanol_s is out of the hard bounds.
Warning: Species concentration Sarcosine_s is out of the soft bounds.
Error: Species concentration Collagen_CONA1_c is out of the hard bounds.
Error: Species concentration Lignocerate_c is out of the hard bounds.
Error: Species concentration (R)-5-Phosphomevalonate_p is out of the hard bounds.
Error: Species concentration Hydracrylate_m is out of the hard bounds.
Error: Species concentration prostaglandin-f1alpha_c is out of the hard bounds.
Error: Species concentration dUMP_m is out of the hard bounds.
Error: Species concentration 5-Hydroxyindoleacetate_c is out of the hard bounds.
Error: Species concentration Dimethylallyl-PP_p is out of the hard bounds.
Error: Species concentration decanoic-acid_s is out of the hard bounds.
Warning: Species concentration Glutamine_l is out of the soft bounds.
p-cumic alcohol:NAD+ oxidoreductase Glycine, serine and threonine metabolism EC:1.2.1.8
Warning: Species concentration PAPS_c is out of the soft bounds.
Warning: Species concentration (S)-3-hydroxypalmitoleoyl-CoA_m is out of the soft bounds.
Error: Species concentration FAD_s is out of the hard bounds.
Error: Species concentration Collagen_COJA1_c is out of the hard bounds.
5,6-Dihydrouracil:NAD+ oxidoreductase Pyrimidine metabolism EC:1.3.1.1
IMP:L-aspartate ligase (GDP-forming) Purine metabolism / Alanine and aspartate metabolism EC:6.3.4.4
Error: Species concentration Orotate_c is out of the hard bounds.
Warning: Species concentration Kynurenine_c is out of the soft bounds.
2'-Deoxyguanosine 5'-triphosphate pyrophosphohydrolase Purine metabolism EC:3.6.1.19
Error: Species concentration Serotonin_b is out of the hard bounds.
ATP:citrate oxaloacetate-lyase ((pro-3S)-CH2COO- ->acetyl-CoA) (ATP-dephosphorylating) Citrate cycle (TCA cycle) EC:2.3.3.8
Error: Species concentration ITP_s is out of the hard bounds.
Error: Species concentration 1-Acylglycerol-3P-lin_c is out of the hard bounds.
Warning: Species concentration ATP_p is out of the soft bounds.
Warning: Species concentration Homoserine_c is out of the soft bounds.
Warning: Species concentration Propanoate_m is out of the soft bounds.
GTP:L-fucose-1-phosphate guanylyltransferase Fructose and mannose metabolism EC:2.7.7.30
Warning: Species concentration trans-4-Hydroxy-L-proline_c is out of the soft bounds.
Error: Species concentration Mannose-1P_c is out of the hard bounds.
Warning: Species concentration prostaglandin-e1_c is out of the soft bounds.
Warning: Species concentration Asparagine_l is out of the soft bounds.
Warning: Species concentration Protoporphyrinogen_IX_c is out of the soft bounds.
Warning: Species concentration Thioredoxin-redox-potential_m is out of the soft bounds.
Error: Species concentration dGDP_c is out of the hard bounds.
Warning: Species concentration Succinyl-CoA_m is out of the soft bounds.
Error: Species concentration CTP_s is out of the hard bounds.
Warning: Species concentration L-3-Cyanoalanine_s is out of the soft bounds.
Warning: Species concentration Leucine_m is out of the soft bounds.
S-Adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase Glycerophospholipid metabolism EC:2.1.1.103
Warning: Species concentration prostaglandin-a2_s is out of the soft bounds.
L-Serine hydro-lyase (adding homocysteine) Glycine, serine and threonine metabolism EC:4.2.1.22
Warning: Species concentration 1,2-Diacylglycerol-VLDL-PE-pool_c is out of the soft bounds.
Warning: Species concentration NH4+_s is out of the soft bounds.
Error: Species concentration CDP_s is out of the hard bounds.
Warning: Species concentration Collagen_COHA1_c is out of the soft bounds.
Error: Species concentration CO2_b is out of the hard bounds.
Error: Species concentration Collagen_BGH3_c is out of the hard bounds.
Error: Species concentration Activated_methyl_group_c is out of the hard bounds.
Warning: Species concentration CMP-NeuNGc_c is out of the soft bounds.
Warning: Species concentration 3-Hydroxystearoyl-ACP_c is out of the soft bounds.
Warning: Species concentration Collagen_COBA1_c is out of the soft bounds.
Warning: Species concentration Thiamin_c is out of the soft bounds.
Error: Species concentration 6-Phospho-D-gluconate_r is out of the hard bounds.
Error: Species concentration ApoC3_c is out of the hard bounds.
Warning: Species concentration 3-Oxodecanoyl-CoA_p is out of the soft bounds.
Mitochondrial Carrier (MC) TCDB:2.A.29.21.1
Error: Species concentration Arachidonate_p is out of the hard bounds.
Error: Species concentration 4-Aminobutanal_s is out of the hard bounds.
Error: Species concentration Hydroxymethylglutathione_c is out of the hard bounds.
Tetradecanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) Fatty acid biosynthesis EC:2.3.1.85
Error: Species concentration Fumarate_c is out of the hard bounds.
Error: Species concentration 1-Acylglycerol-3P-stea_c is out of the hard bounds.
Fe(II):oxygen oxidoreductase Porphyrin and chlorophyll metabolism EC:1.16.3.1
Error: Species concentration Chitobiose_s is out of the hard bounds.
Carbonic acid hydro-lyase Nitrogen metabolism EC:4.2.1.1
Warning: Species concentration Phenylacetate_c is out of the soft bounds.
ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating) Biosynthesis of steroids EC:4.1.1.33
Warning: Species concentration 4-Aminobutyrate_c is out of the soft bounds.
5,10-methylenetetrahydrofolate:NADP+ oxidoreductase Glyoxylate and dicarboxylate metabolism / One carbon pool by folate EC:1.5.1.5
Deamino-NAD+ nucleotidohydrolase Nicotinate and nicotinamide metabolism EC:3.6.1.9
Warning: Species concentration Acetone_s is out of the soft bounds.
Nicotinamide-nucleotide:pyrophosphate phospho-alpha-D-ribosyltransferase Nicotinate and nicotinamide metabolism EC:2.4.2.12
hexadecanal:NADP+ delta2-oxidoreductase EC:1.3.1.27
Warning: Species concentration Thymidine_s is out of the soft bounds.
Warning: Species concentration Acyl-CoA-VLDL-TG2-pool_c is out of the soft bounds.
Warning: Species concentration Cholestenol_r is out of the soft bounds.
Error: Species concentration L-Octanoylcarnitine_m is out of the hard bounds.
Error: Species concentration Glutamate_s is out of the hard bounds.
ATP:FMN adenylyltransferase Riboflavin metabolism EC:2.7.7.2
Error: Species concentration Cholate_r is out of the hard bounds.
Warning: Species concentration prostaglandin-g2_s is out of the soft bounds.
Error: Species concentration Collagen_CO5A2_c is out of the hard bounds.
Succinate-semialdehyde:NADP+ oxidoreductase Glutamate metabolism / Tyrosine metabolism / Butanoate metabolism EC:1.2.1.16
Warning: Species concentration Acetoacetyl-CoA_p is out of the soft bounds.
Error: Species concentration ApoA1_s is out of the hard bounds.
Error: Species concentration Cholesterol-ester-palm_l is out of the hard bounds.
ATP-binding Cassette (ABC) TCDB:3.A.1.208.7
Warning: Species concentration Choloyl-CoA_r is out of the soft bounds.
Error: Species concentration mitoACP_m is out of the hard bounds.
Warning: Species concentration Ribulose-5P_r is out of the soft bounds.
Error: Species concentration Fatty-acid-VLDL-TG2-pool_c is out of the hard bounds.
Error: Species concentration sulfoglycolithocholate_s is out of the hard bounds.
Warning: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanate_r is out of the soft bounds.
Error: Species concentration Tetradecanoyl-ACP_c is out of the hard bounds.
Error: Species concentration Propinol_adenylate_c is out of the hard bounds.
Error: Species concentration Citrulline_s is out of the hard bounds.
alcohol dehydrogenase Bile acid biosynthesis EC:1.1.1.1
Phosphoethanolamine phosphohydrolase Glycerophospholipid metabolism EC:3.1.3.75
Warning: Species concentration Collagen_COMA1_c is out of the soft bounds.
Warning: Species concentration Tryptophan_l is out of the soft bounds.
Warning: Species concentration Ferricytochrome_b5_c is out of the soft bounds.
Error: Species concentration NADH-redox-potential_m is out of the hard bounds.
Phosphatidylethanolamine cholinephosphohydrolase Glycine, serine and threonine metabolism / Glycerophospholipid metabolism EC:3.1.4.3
Warning: Species concentration CTP_n is out of the soft bounds.
Error: Species concentration Serine_s is out of the hard bounds.
Pyridoxine:oxygen oxidoreductase (deaminating) Vitamin B6 metabolism EC:1.1.3.12
L-Citrulline:L-aspartate ligase (AMP-forming) Urea cycle and metabolism of amino groups / Alanine and aspartate metabolism / Arginine and proline metabolism EC:6.3.4.5
Warning: Species concentration Succinate_s is out of the soft bounds.
Error: Species concentration Glucose-1P_c is out of the hard bounds.
Error: Species concentration L-Octanoylcarnitine_c is out of the hard bounds.
Warning: Species concentration Glycerol_s is out of the soft bounds.
Warning: Species concentration AMP_s is out of the soft bounds.
Error: Species concentration (2E)-Hexadecenoyl-CoA_r is out of the hard bounds.
Warning: Species concentration Arachidonate_r is out of the soft bounds.
Error: Species concentration Tyrosine_c is out of the hard bounds.
Error: Species concentration IMP_s is out of the hard bounds.
Warning: Species concentration CMP_s is out of the soft bounds.
hydroxysteroid (17-beta) dehydrogenase 7 Biosynthesis of steroids EC:1.1.1.270
Error: Species concentration Glucose_c is out of the hard bounds.
Error: Species concentration 3-Oxopalmitoyl-CoA_p is out of the hard bounds.
Warning: Species concentration Sedoheptulose-7P_c is out of the soft bounds.
Warning: Species concentration dGMP_m is out of the soft bounds.
Warning: Species concentration cAMP_c is out of the soft bounds.
Error: Species concentration Carnosine_c is out of the hard bounds.
folylpolyglutamyl synthetase EC:6.3.2.17
Error: Species concentration ApoTransferin_l is out of the hard bounds.
Warning: Species concentration Acyl-CoA-VLDL-SM-pool_c is out of the soft bounds.
Mitochondrial Carrier (MC) TCDB:2.A.29.14.2
Error: Species concentration 5-Aminolevulinate_c is out of the hard bounds.
Warning: Species concentration 3alpha,7alpha-Dihydroxy-5beta-cholestanate_p is out of the soft bounds.
N6-(L-1,3-Dicarboxypropyl)-L-lysine:NAD+ oxidoreductase; N6-(L-1,3-Dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming) Lysine degradation EC:1.5.1.9
Error: Species concentration Dihydroneopterin_s is out of the hard bounds.
NADPH:oxidized-thioredoxin oxidoreductase Pyrimidine metabolism EC:1.8.1.9
Error: Species concentration Choline_c is out of the hard bounds.
Error: Species concentration N-Formyl-GAR_c is out of the hard bounds.
Error: Species concentration Ethanolamine-P_c is out of the hard bounds.
Error: Species concentration Methionine_m is out of the hard bounds.
Error: Species concentration GSSG_s is out of the hard bounds.
Error: Species concentration Cholesterol-ester-stea_l is out of the hard bounds.
Error: Species concentration ApoE_l is out of the hard bounds.
Warning: Species concentration 3-Methylglutaconyl-CoA_m is out of the soft bounds.
Error: Species concentration Oxalate_m is out of the hard bounds.
Error: Species concentration mitoOxidizedThioredoxin_m is out of the hard bounds.
Warning: Species concentration 3-Oxopalmitoyl-CoA_p is out of the soft bounds.
Warning: Species concentration FAICAR_c is out of the soft bounds.
Warning: Species concentration GDP-mannose_c is out of the soft bounds.
Warning: Species concentration Glyceraldehyde_c is out of the soft bounds.
Warning: Species concentration Histidine_l is out of the soft bounds.
Error: Species concentration Prothrombin_l is out of the hard bounds.
Error: Species concentration L-Fucose-1P_c is out of the hard bounds.
Adenosine 3',5'-bisphosphate 3'(2')-phosphohydrolase EC:3.1.3.7
Warning: Species concentration NAD+_p is out of the soft bounds.
L-Arginine amidinohydrolase Urea cycle and metabolism of amino groups / Arginine and proline metabolism EC:3.5.3.1
Warning: Species concentration Taurine_c is out of the soft bounds.
Error: Species concentration 6-Lactoyl-5,6,7,8-tetrahydropterin_c is out of the hard bounds.
Warning: Species concentration Bilirubin_s is out of the soft bounds.
Warning: Species concentration Thymine_c is out of the soft bounds.
Error: Species concentration NH4+_c is out of the hard bounds.
Warning: Species concentration Isocitrate_c is out of the soft bounds.
Dodecanoyl-[acyl-carrier protein]: malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) Fatty acid biosynthesis EC:2.3.1.85
Warning: Species concentration HCO3-_m is out of the soft bounds.
Warning: Species concentration Glycine_m is out of the soft bounds.
Error: Species concentration Deoxyinosine_c is out of the hard bounds.
Warning: Species concentration H+(PG)_m is out of the soft bounds.
Warning: Species concentration ApoC2_r is out of the soft bounds.
Sphinganine-1-phosphate pamlmitaldehyde-lyase Sphingolipid metabolism EC:4.1.2.27
Warning: Species concentration Fatty-acid-VLDL-PI-pool_c is out of the soft bounds.
Error: Species concentration 1-Acylglycerol-3P-palm_c is out of the hard bounds.
Error: Species concentration Malonyl-CoA_c is out of the hard bounds.
Error: Species concentration 2-Aminomuconate_c is out of the hard bounds.
Error: Species concentration Deoxyuridine_s is out of the hard bounds.
Error: Species concentration Deoxyadenosine_c is out of the hard bounds.
Error: Species concentration ATP_m is out of the hard bounds.
S-Adenosyl-L-methionine:glycine methyltransferase Glycine, serine and threonine metabolism EC:2.1.1.20
Nicotinate-nucleotide:pyrophosphate phosphoribosyltransferase (carboxylating) Nicotinate and nicotinamide metabolism EC:2.4.2.19
Error: Species concentration L-1-Pyrroline-3-hydroxy-5-carboxylate_m is out of the hard bounds.
Error: Species concentration 1-Acylglycerol-3P-VLDL-PS-pool_c is out of the hard bounds.
Warning: Species concentration Octanoyl-CoA_p is out of the soft bounds.
Error: Species concentration L-Oleoylcarnitine_m is out of the hard bounds.
Error: Species concentration Glycogenin-G7_c is out of the hard bounds.
Warning: Species concentration 1-Pyrroline-5-carboxylate_m is out of the soft bounds.
Warning: Species concentration Ubiquinol_m is out of the soft bounds.
Error: Species concentration NADP+_r is out of the hard bounds.
Error: Species concentration K+_s is out of the hard bounds.
ATP:Sedoheptulose 7-phosphate 1-phosphotransferase EC:2.7.1.11
Error: Species concentration PC-VLDL-pool_r is out of the hard bounds.
Error: Species concentration Propanoyl-CoA_p is out of the hard bounds.
Warning: Species concentration Propanoyl-CoA_c is out of the soft bounds.
Warning: Species concentration Carbonate_s is out of the soft bounds.
Error: Species concentration 2,5-Diaminopyrimidine_nleoside_triphosphate_c is out of the hard bounds.
Error: Species concentration 1,2-Diacylglycerol-Bile-PC-pool_c is out of the hard bounds.
Error: Species concentration prostaglandin-a1_s is out of the hard bounds.
Warning: Species concentration S-(3-Methylbutanoyl)-dihydrolipoamide_m is out of the soft bounds.
Warning: Species concentration leukotriene-a4_s is out of the soft bounds.
collagen, type III, alpha 1 Protein assembly
Error: Species concentration GDP_m is out of the hard bounds.
Warning: Species concentration Proline_l is out of the soft bounds.
Warning: Species concentration THF-activated_methyl_group_c is out of the soft bounds.
Error: Species concentration palmitoleoyl-CoA_m is out of the hard bounds.
Warning: Species concentration Malonate_m is out of the soft bounds.
Warning: Species concentration Xylitol_c is out of the soft bounds.
Warning: Species concentration prostaglandin-d1_s is out of the soft bounds.
Warning: Species concentration H2S2O3_c is out of the soft bounds.
Warning: Species concentration Spermine_s is out of the soft bounds.
Warning: Species concentration Malate_m is out of the soft bounds.
Warning: Species concentration Linoleate_p is out of the soft bounds.
Warning: Species concentration 1-Acylglycerol-3P-ol_c is out of the soft bounds.
Error: Species concentration Guanosine_s is out of the hard bounds.
Warning: Species concentration Lauroyl-CoA_p is out of the soft bounds.
Warning: Species concentration Palmitoyl-CoA_m is out of the soft bounds.
Error: Species concentration Cysteine_l is out of the hard bounds.
Warning: Species concentration leukotriene-f4_c is out of the soft bounds.
Error: Species concentration Lysine_c is out of the hard bounds.
Warning: Species concentration Sedoheptulose-1,7PP_c is out of the soft bounds.
Warning: Species concentration H2S_s is out of the soft bounds.
Glycerol:NADP+ oxidoreductase Glycerolipid metabolism EC:1.1.1.72 EC:1.1.1.2
Error: Species concentration L-Carnitine_c is out of the hard bounds.
Error: Species concentration 20-hydroxy-arachidonate_c is out of the hard bounds.
Error: Species concentration Dopamine_c is out of the hard bounds.
Warning: Species concentration Haptoglobin_l is out of the soft bounds.
5,6-Dihydrothymine:NAD+ oxidoreductase Pyrimidine metabolism EC:1.3.1.1
Warning: Species concentration 3-Methoxy-4-hydroxyphenylglycolaldehyde_m is out of the soft bounds.
Warning: Species concentration 3-Oxododecanoyl-CoA_m is out of the soft bounds.
GTP:alpha-D-mannose-1-phosphate guanylyltransferase Fructose and mannose metabolism EC:2.7.7.13
Error: Species concentration H2O_c is out of the hard bounds.
Error: Species concentration Urea_s is out of the hard bounds.
Warning: Species concentration Chenodiol_b is out of the soft bounds.
Error: Species concentration Urate_p is out of the hard bounds.
Error: Species concentration Urate_c is out of the hard bounds.
GTP phosphohydrolase (vesicle-releasing) Purine metabolism EC:3.6.5.5 EC:3.6.5.1 EC:3.6.5.6 EC:3.6.5.2 EC:3.6.5.3 EC:3.6.5.4
Error: Species concentration 5,10-Methylene-THF_m is out of the hard bounds.
Error: Species concentration 4-Maleylacetoacetate_c is out of the hard bounds.
Error: Species concentration prostaglandin-d1_c is out of the hard bounds.
Error: Species concentration Glycochenodeoxycholate_s is out of the hard bounds.
Warning: Species concentration Methionine_c is out of the soft bounds.
Error: Species concentration Succinate_s is out of the hard bounds.
Warning: Species concentration H2O2_s is out of the soft bounds.
Error: Species concentration myristic-acid_s is out of the hard bounds.
Warning: Species concentration 1-Acylglycerol-VLDL-TG1-pool_c is out of the soft bounds.
CDPdiacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase Glycerophospholipid metabolism EC:2.7.8.5
Error: Species concentration Taurine_p is out of the hard bounds.
Error: Species concentration PE-VLDL-pool_l is out of the hard bounds.
Warning: Species concentration Collagen_CO6A5_c is out of the soft bounds.
Warning: Species concentration Orotidine-5P_c is out of the soft bounds.
Error: Species concentration GDP_c is out of the hard bounds.
Error: Species concentration Formaldehyde_c is out of the hard bounds.
Error: Species concentration Acyl-CoA-CL-pool_c is out of the hard bounds.
5,10-Methenyltetrahydrofolate 5-hydrolase(decyclizing) Glyoxylate and dicarboxylate metabolism / One carbon pool by folate EC:3.5.4.9
Error: Species concentration Isocitrate_p is out of the hard bounds.
L-proline:(acceptor) oxidoreductase Arginine and proline metabolism EC:1.5.99.8
Warning: Species concentration Cholesterol-ester-pool_r is out of the soft bounds.
Error: Species concentration Acetaldehyde_s is out of the hard bounds.
Farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase Biosynthesis of steroids EC:2.5.1.21
Error: Species concentration AKG_c is out of the hard bounds.
Warning: Species concentration Citrate_s is out of the soft bounds.
Error: Species concentration Formylglutathione_c is out of the hard bounds.
Warning: Species concentration Palmitolate_s is out of the soft bounds.
5alpha-Cholest-7-en-3beta-ol delta7-delta8-isomerase Biosynthesis of steroids EC:5.3.3.5
Warning: Species concentration mitoThioredoxin_c is out of the soft bounds.
Warning: Species concentration Stearate_l is out of the soft bounds.
Error: Species concentration Malonyl-CoA_r is out of the hard bounds.
Error: Species concentration Octanoyl-CoA_p is out of the hard bounds.
citrate hydro-lyase Citrate cycle (TCA cycle) / Glyoxylate and dicarboxylate metabolism EC:4.2.1.4
cardiolipin synthase 1 Glycerophospholipid metabolism EC:2.7.8.-
Error: Species concentration Glutamate_m is out of the hard bounds.
Error: Species concentration reverse-triiodthyronine_s is out of the hard bounds.
Warning: Species concentration Acetoacetate_m is out of the soft bounds.
Error: Species concentration Serine_m is out of the hard bounds.
Error: Species concentration ATP_r is out of the hard bounds.
Error: Species concentration Riboflavin_s is out of the hard bounds.
Warning: Species concentration sn-Glycerol-3P_p is out of the soft bounds.
Error: Species concentration Collagen_ITA2_c is out of the hard bounds.
Warning: Species concentration Lignocerate_s is out of the soft bounds.
Warning: Species concentration (2E)-Hexadecenoyl-CoA_p is out of the soft bounds.
Warning: Species concentration Estrone_3-sulfate_c is out of the soft bounds.
Error: Species concentration 3-Hydroxystearoyl-ACP_c is out of the hard bounds.
Error: Species concentration NADPH-redox-potential_r is out of the hard bounds.
Error: Species concentration Histamine_c is out of the hard bounds.
Acetyl-CoA hydrolase Pyruvate metabolism EC:3.1.2.1
Error: Species concentration prostaglandin-e2_s is out of the hard bounds.
Error: Species concentration Fructose-6P_c is out of the hard bounds.
transforming growth factor, beta induced Protein assembly
Error: Species concentration Palmitate_c is out of the hard bounds.
alpha-D-Glucoside glucohydrolase Starch and sucrose metabolism EC:3.2.1.20
Error: Species concentration Acyl-CoA-VLDL-PS-pool_c is out of the hard bounds.
Error: Species concentration 1-Acylglycerol-VLDL-PS-pool_c is out of the hard bounds.
Warning: Species concentration PNP_s is out of the soft bounds.
Error: Species concentration Collagen_CO2A1_c is out of the hard bounds.
4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating) Tyrosine metabolism EC:1.13.11.27
Error: Species concentration leukotriene-e4_c is out of the hard bounds.
Error: Species concentration Citrulline_c is out of the hard bounds.
Warning: Species concentration Noradrenaline_s is out of the soft bounds.
Error: Species concentration Decanoyl-CoA_m is out of the hard bounds.
Hexadecanoyl-[acyl-carrier protein:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) Fatty acid biosynthesis EC:2.3.1.85
Warning: Species concentration Collagen_CCBE1_c is out of the soft bounds.
Warning: Species concentration 1-Acylglycerol-3P-palmn_c is out of the soft bounds.
Warning: Species concentration 3,4-Dihydroxymandelaldehyde_m is out of the soft bounds.
trans-Tetradec-2-enoyl-CoA reductase Fatty acid elongation in mitochondria EC:1.3.1.38
Error: Species concentration 3,4-Dihydroxymandelate_m is out of the hard bounds.
Error: Species concentration 3-Oxodecanoyl-CoA_m is out of the hard bounds.
Warning: Species concentration UDP-glucuronate_r is out of the soft bounds.
Error: Species concentration Phenylacetate_c is out of the hard bounds.
Nicotinate D-ribonucleotide:pyrophosphate phosphoribosyltransferase Nicotinate and nicotinamide metabolism EC:2.4.2.11
Collagen alpha-1(XVII) chain Protein assembly
Error: Species concentration Ribose_c is out of the hard bounds.
Warning: Species concentration 5,10-Methenyl-THF_m is out of the soft bounds.
Uroporphyrinogen-III carboxy-lyase Porphyrin and chlorophyll metabolism EC:4.1.1.37
(S)-2-methylbutanoyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-(2-methylbutanoyl)transferase Valine, leucine and isoleucine degradation EC:2.3.1.168
Warning: Species concentration Propanoate_s is out of the soft bounds.
Error: Species concentration Hexadecanal_c is out of the hard bounds.
3-Methoxy-4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase Tyrosine metabolism EC:1.2.1.5
Warning: Species concentration Valine_s is out of the soft bounds.
Error: Species concentration trans,cis-dodeca-2,5-dienoyl-CoA_m is out of the hard bounds.
Error: Species concentration palmitoleoyl-CoA_c is out of the hard bounds.
Warning: Species concentration Adenosine_c is out of the soft bounds.
Warning: Species concentration Retinoate_s is out of the soft bounds.
Error: Species concentration gamma-Linolenate_r is out of the hard bounds.
Error: Species concentration Acetoacetyl-CoA_p is out of the hard bounds.
L-Asparagine amidohydrolase Alanine and aspartate metabolism / Cyanoamino acid metabolism / Nitrogen metabolism EC:3.5.1.1 EC:3.5.1.38
Warning: Species concentration (2E)-Decenoyl-CoA_p is out of the soft bounds.
Warning: Species concentration ApoE_r is out of the soft bounds.
7-dehydrocholesterol reductase Biosynthesis of steroids EC:1.3.1.21
Error: Species concentration Ribulose-5P_r is out of the hard bounds.
Warning: Species concentration sulfoglycolithocholate_c is out of the soft bounds.
Warning: Species concentration cis-(3S)-hydroxytetradec-7-enoyl-CoA_m is out of the soft bounds.
Warning: Species concentration UDP-glucose_r is out of the soft bounds.
Error: Species concentration 1-Acylglycerol-3P-VLDL-PC-pool_c is out of the hard bounds.
Warning: Species concentration Plasminogen_s is out of the soft bounds.
Warning: Species concentration S-Acetyldihydrolipoamide_m is out of the soft bounds.
Error: Species concentration ADP_c is out of the hard bounds.
Warning: Species concentration CMP_m is out of the soft bounds.
Error: Species concentration Formaldehyde_s is out of the hard bounds.
Error: Species concentration Palmitolate_l is out of the hard bounds.
ATP:(R)-5-phosphomevalonate phosphotransferase Biosynthesis of steroids EC:2.7.4.2
Error: Species concentration prostaglandin-f2alpha_c is out of the hard bounds.
Warning: Species concentration 5-Formiminotetrahydrofolate_c is out of the soft bounds.
Error: Species concentration 5-Aminolevulinate_m is out of the hard bounds.
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase Purine metabolism EC:4.3.2.2
Warning: Species concentration prostaglandin-f2beta_s is out of the soft bounds.
Warning: Species concentration NADH-redox-potential_c is out of the soft bounds.
Warning: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA_r is out of the soft bounds.
Error: Species concentration gamma-Glutamyl-3-aminopropiononitrile_s is out of the hard bounds.
Error: Species concentration CTP_n is out of the hard bounds.
Warning: Species concentration Collagen_CO5A1_c is out of the soft bounds.
ATP:N-acyl-D-mannosamine 6-phosphotransferase Aminosugars metabolism EC:2.7.1.60
Error: Species concentration Elaidate_s is out of the hard bounds.
collagen, type VI, alpha 5 Protein assembly
Warning: Species concentration 3-Oxotetradecanoyl-ACP_c is out of the soft bounds.
Warning: Species concentration Acetyl-CoA_m is out of the soft bounds.
Error: Species concentration Betaine_c is out of the hard bounds.
Warning: Species concentration UDP-activated-galactose_c is out of the soft bounds.
Warning: Species concentration 4-Methyl-2-oxopentanoate_m is out of the soft bounds.
Error: Species concentration ApoC1_c is out of the hard bounds.
L-Histidine:4-aminobutanoate ligase (AMP-forming) Urea cycle and metabolism of amino groups EC:6.3.2.11
Error: Species concentration Tryptophan_s is out of the hard bounds.
Error: Species concentration Histidine_l is out of the hard bounds.
Warning: Species concentration 5beta-Cholestane-3alpha,7alpha,12alpha,26-tetrol_c is out of the soft bounds.
Error: Species concentration AMP_s is out of the hard bounds.
aldehyde oxidase Tyrosine metabolism EC:1.2.3.1
Error: Species concentration (2E)-Hexadecenoyl-CoA_c is out of the hard bounds.
Warning: Species concentration Phosphopantetheine_c is out of the soft bounds.
Error: Species concentration Arachidonate_r is out of the hard bounds.
L-Ornithine:2-oxo-acid aminotransferase Arginine and proline metabolism EC:2.6.1.13
Error: Species concentration GM4-pool_c is out of the hard bounds.
Warning: Species concentration Glucose_r is out of the soft bounds.
Warning: Species concentration PC-VLDL-pool_c is out of the soft bounds.
Error: Species concentration Collagen_CO4A2_c is out of the hard bounds.
Warning: Species concentration Galactose_s is out of the soft bounds.
ATP:ethanolamine O-phosphotransferase Glycerophospholipid metabolism EC:2.7.1.82
Collagen alpha-1(IV) chain Protein assembly
Error: Species concentration ApoA1_r is out of the hard bounds.
Error: Species concentration (2E)-Decenoyl-ACP_c is out of the hard bounds.
Error: Species concentration Sarcosine_c is out of the hard bounds.
Error: Species concentration Methanol_s is out of the hard bounds.
Error: Species concentration Pyruvate_s is out of the hard bounds.
Warning: Species concentration Formate_c is out of the soft bounds.
Warning: Species concentration SAICAR_c is out of the soft bounds.
Error: Species concentration palmitoleoyl-Carnitine_r is out of the hard bounds.
beta-1,4-galactosyltransferase 6 Sphingolipid metabolism EC:2.4.1.-
Warning: Species concentration (R)-3-Hydroxybutanoate_m is out of the soft bounds.
Warning: Species concentration 6-Phospho-D-gluconate_c is out of the soft bounds.
Warning: Species concentration Cholesterol-ester-stea_r is out of the soft bounds.
Error: Species concentration 3-Methylglutaconyl-CoA_m is out of the hard bounds.
Warning: Species concentration Oxalate_c is out of the soft bounds.
Warning: Species concentration THF-activated_methylene_group_m is out of the soft bounds.
Warning: Species concentration prostaglandin-d3_s is out of the soft bounds.
Error: Species concentration prostaglandin-a2_s is out of the hard bounds.
Warning: Species concentration (S)-3-Hydroxybutyryl-CoA_m is out of the soft bounds.
UDPglucose 4-epimerase Galactose metabolism / Nucleotide sugars metabolism EC:5.1.3.2
Error: Species concentration GDP-mannose_c is out of the hard bounds.
Error: Species concentration 3-Hydroxypropionyl-CoA_m is out of the hard bounds.
Error: Species concentration Lauroyl-CoA_p is out of the hard bounds.
Error: Species concentration UDP-N-acetylglucosamine_r is out of the hard bounds.
Deoxyadenosine aminohydrolase Purine metabolism EC:3.5.4.4
Warning: Species concentration Noradrenaline_c is out of the soft bounds.
Warning: Species concentration CO2_r is out of the soft bounds.
Warning: Species concentration Cholesterol_l is out of the soft bounds.
Warning: Species concentration prostaglandin-i2_c is out of the soft bounds.
Error: Species concentration thromboxane-b2_c is out of the hard bounds.
Coproporphyrinogen:oxygen oxidoreductase(decarboxylating) Porphyrin and chlorophyll metabolism EC:1.3.3.3
Warning: Species concentration Collagen_COFA1_c is out of the soft bounds.
Error: Species concentration Phosphatidate-VLDL-PC-pool_c is out of the hard bounds.
Error: Species concentration 3-Methylcrotonyl-CoA_m is out of the hard bounds.
7alpha-hydroxycholest-4-en-3-one,NADPH:oxygen oxidoreductase(12alpha-hydroxylating) Bile acid biosynthesis EC:1.14.-.-
Warning: Species concentration Cholesterol-ester-lin_l is out of the soft bounds.
Error: Species concentration CMP_r is out of the hard bounds.
Error: Species concentration (S)-Hydroxydecanoyl-CoA_m is out of the hard bounds.
Error: Species concentration Bilirubin_s is out of the hard bounds.
Warning: Species concentration Arachidonate_l is out of the soft bounds.
Protoporphyrin ferro-lyase Porphyrin and chlorophyll metabolism EC:4.99.1.1
5-Methyltetrahydrofolate:L-homocysteine S-methyltransferase Methionine metabolism / One carbon pool by folate EC:2.1.1.13
Warning: Species concentration Pyridoxal-P_s is out of the soft bounds.
Error: Species concentration Isocitrate_c is out of the hard bounds.
amylo-1,6-glucosidase, 4-alpha-glucanotransferase EC:3.2.1.33
Error: Species concentration beta-Alanine_c is out of the hard bounds.
Error: Species concentration Phenylacetaldehyde_c is out of the hard bounds.
Warning: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-24-oxocholestanoyl-CoA_p is out of the soft bounds.
Error: Species concentration H+(PG)_m is out of the hard bounds.
Error: Species concentration Tryptophan_c is out of the hard bounds.
Error: Species concentration 2-Methyl-3-oxopropanoate_c is out of the hard bounds.
Error: Species concentration L-Carnitine_p is out of the hard bounds.
Error: Species concentration GM2-pool_s is out of the hard bounds.
Error: Species concentration Albumin_l is out of the hard bounds.
Error: Species concentration PEP_m is out of the hard bounds.
Warning: Species concentration Alanine_s is out of the soft bounds.
Error: Species concentration Triphosphate_c is out of the hard bounds.
Error: Species concentration L-Lactate_p is out of the hard bounds.
Error: Species concentration PS-VLDL-pool_c is out of the hard bounds.
Warning: Species concentration L-1-Pyrroline-3-hydroxy-5-carboxylate_c is out of the soft bounds.
Warning: Species concentration Glucono-1,5-lactone-6P_r is out of the soft bounds.
Warning: Species concentration gamma-Glutamyl-cysteine_c is out of the soft bounds.
Error: Species concentration 3-Dehydrosphinganine_c is out of the hard bounds.
Warning: Species concentration Choline_s is out of the soft bounds.
Error: Species concentration Butyryl-ACP_c is out of the hard bounds.
Error: Species concentration 3-Oxostearoyl-ACP_c is out of the hard bounds.
Warning: Species concentration Presqualene-PP_r is out of the soft bounds.
Error: Species concentration Pyridoxine_s is out of the hard bounds.
Warning: Species concentration 3-Oxotetradecanoyl-CoA_m is out of the soft bounds.
Warning: Species concentration Leukotriene_C4_s is out of the soft bounds.
Error: Species concentration AKG_m is out of the hard bounds.
Octanoyl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) Fatty acid biosynthesis EC:2.3.1.85
10-Formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4- imidazolecarboxamide formyltransferase Purine metabolism / One carbon pool by folate EC:2.1.2.3
(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase Valine, leucine and isoleucine degradation EC:1.1.1.178
Warning: Species concentration 3-Phosphoserine_c is out of the soft bounds.
Warning: Species concentration prostaglandin-e3_s is out of the soft bounds.
Error: Species concentration HDL_s is out of the hard bounds.
Error: Species concentration Proline_l is out of the hard bounds.
Warning: Species concentration NADH-redox-potential_r is out of the soft bounds.
Warning: Species concentration 5-Hydroxyindoleacetaldehyde_c is out of the soft bounds.
Warning: Species concentration LDL_l is out of the soft bounds.
Warning: Species concentration Palmitate_l is out of the soft bounds.
Warning: Species concentration Acyl-CoA-VLDL-PC-pool_c is out of the soft bounds.
Error: Species concentration prostaglandin-b2_c is out of the hard bounds.
Warning: Species concentration dGDP_m is out of the soft bounds.
Error: Species concentration Leucine_s is out of the hard bounds.
solute carrier family 29 (nucleoside transporters), member 1 TCDB:2.A.57.1.1 TCDB:2.A.57.1.4
Warning: Species concentration FAD_c is out of the soft bounds.
Warning: Species concentration Collagen_COLQ_c is out of the soft bounds.
Error: Species concentration leukotriene-f4_c is out of the hard bounds.
Warning: Species concentration NADPH-redox-potential_c is out of the soft bounds.
Glycerone phosphate phosphohydrolase (alkaline optimum) EC:3.1.3.1
Error: Species concentration CDP-ethanolamine_c is out of the hard bounds.
Warning: Species concentration Hexanoyl-CoA_m is out of the soft bounds.
Error: Species concentration 5beta-Cholestane-3alpha,7alpha,26-triol_c is out of the hard bounds.
Error: Species concentration ATP_p is out of the hard bounds.
L-Proline:NAD+ 5-oxidoreductase Arginine and proline metabolism EC:1.5.1.2
Warning: Species concentration Myristoyl-CoA_p is out of the soft bounds.
Error: Species concentration Ornithine_m is out of the hard bounds.
Warning: Species concentration 3-Hydroxyanthranilate_c is out of the soft bounds.
Error: Species concentration prostaglandin-e1_c is out of the hard bounds.
Error: Species concentration Haptoglobin_l is out of the hard bounds.
Error: Species concentration 3-Methoxy-4-hydroxyphenylglycolaldehyde_m is out of the hard bounds.
Error: Species concentration UMP_c is out of the hard bounds.
Error: Species concentration Malate_m is out of the hard bounds.
Error: Species concentration Butyrate_s is out of the hard bounds.
UDP-N-acetyl-D-glucosamine 4-epimerase Aminosugars metabolism EC:5.1.3.7
Warning: Species concentration dAMP_c is out of the soft bounds.
Error: Species concentration Chenodiol_b is out of the hard bounds.
Error: Species concentration Deoxyguanosine_m is out of the hard bounds.
Warning: Species concentration Bile-PC-pool_b is out of the soft bounds.
Error: Species concentration Leucine_m is out of the hard bounds.
10-formyltetrahydrofolate:NADP+ oxidoreductase One carbon pool by folate EC:1.5.1.6
Error: Species concentration 1,2-Diacylglycerol-VLDL-PE-pool_c is out of the hard bounds.
Error: Species concentration Threonine_s is out of the hard bounds.
Error: Species concentration dCTP_c is out of the hard bounds.
Error: Species concentration Glucuronate_c is out of the hard bounds.
N-Acetylneuraminate 9-phosphate pyruvate-lyase (pyruvate-phosphorylating) Aminosugars metabolism EC:2.5.1.57
Collagen alpha-3(V) chain Protein assembly
Warning: Species concentration CDP_c is out of the soft bounds.
Error: Species concentration Collagen_COHA1_c is out of the hard bounds.
Warning: Species concentration Collagen_ADIPO_c is out of the soft bounds.
Error: Species concentration 1-Acylglycerol-VLDL-TG1-pool_c is out of the hard bounds.
Error: Species concentration Agmatine_m is out of the hard bounds.
Error: Species concentration Dihomo-gamma-linolenate_r is out of the hard bounds.
Error: Species concentration CMP-NeuNGc_c is out of the hard bounds.
Warning: Species concentration SAH_c is out of the soft bounds.
Warning: Species concentration Oxidized_thioredoxin_c is out of the soft bounds.
Warning: Species concentration ApoC3_r is out of the soft bounds.
Error: Species concentration 3-Oxodecanoyl-CoA_p is out of the hard bounds.
Error: Species concentration Triiodothyronine_s is out of the hard bounds.
Warning: Species concentration CL-pool_m is out of the soft bounds.
L-Kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating) Tryptophan metabolism EC:1.14.13.9
Error: Species concentration Thioredoxin-redox-potential_m is out of the hard bounds.
ATP:D-galactose 1-phosphotransferase Galactose metabolism EC:2.7.1.6
Error: Species concentration Malonyl-ACP_c is out of the hard bounds.
Warning: Species concentration Ribose_s is out of the soft bounds.
Error: Species concentration D-3-Amino-isobutanoate_s is out of the hard bounds.
Warning: Species concentration Chitobiose_l is out of the soft bounds.
Error: Species concentration Lanosterol_p is out of the hard bounds.
D-Fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase Carbon fixation EC:4.1.2.13
Collagen alpha-1(VI) chain Protein assembly
Propinol adenylate:CoA ligase (AMP-forming) Propanoate metabolism EC:6.2.1.17 EC:6.2.1.1
Error: Species concentration H+(PG)_p is out of the hard bounds.
Error: Species concentration ursodeoxycholate_s is out of the hard bounds.
Error: Species concentration Taurochenodeoxycholate_p is out of the hard bounds.
Warning: Species concentration Tyrosine_m is out of the soft bounds.
Error: Species concentration Tetrahydrobiopterin_c is out of the hard bounds.
Lanosterol,NADPH:oxygen oxidoreductase (14-methyl cleaving) Biosynthesis of steroids EC:1.14.13.70
Error: Species concentration prostaglandin-g2_s is out of the hard bounds.
Warning: Species concentration Methylmalonyl-CoA_m is out of the soft bounds.
2-Oxoglutaramate amidohydrolase Glutamate metabolism EC:3.5.1.3
Error: Species concentration sn-Glycerol-3P_p is out of the hard bounds.
Error: Species concentration Estrone_3-sulfate_c is out of the hard bounds.
collagen, type II, alpha 1 Protein assembly
Error: Species concentration Collagen_CO5A3_c is out of the hard bounds.
Error: Species concentration taurolithocholate_c is out of the hard bounds.
Error: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanate_p is out of the hard bounds.
Error: Species concentration Pyridoxamine_s is out of the hard bounds.
Warning: Species concentration Fatty-acid-VLDL-TG3-pool_c is out of the soft bounds.
Warning: Species concentration PPi_m is out of the soft bounds.
Error: Species concentration Tagatose-1,6PP_c is out of the hard bounds.
Collagen alpha-5(IV) chain Protein assembly
Warning: Species concentration Prothrombin_l is out of the soft bounds.
Error: Species concentration UDP-glucose_c is out of the hard bounds.
Warning: Species concentration (R)-3-Hydroxyoctanoyl-ACP_c is out of the soft bounds.
Warning: Species concentration dUTP_m is out of the soft bounds.
Warning: Species concentration Collagen_CO4A3_c is out of the soft bounds.
Warning: Species concentration Inosine_s is out of the soft bounds.
Error: Species concentration Glycerol_s is out of the hard bounds.
Error: Species concentration 5,10-Methenyl-THF_m is out of the hard bounds.
ATP-binding Cassette (ABC) TCDB:3.A.1.208.9
Warning: Species concentration Tyrosine_s is out of the soft bounds.
Warning: Species concentration Oleoyl-CoA_m is out of the soft bounds.
Warning: Species concentration dATP_c is out of the soft bounds.
Error: Species concentration Spermine_s is out of the hard bounds.
Error: Species concentration Plasminogen_s is out of the hard bounds.
Warning: Species concentration 3alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-CoA_p is out of the soft bounds.
Error: Species concentration cAMP_c is out of the hard bounds.
Warning: Species concentration 2-Aminoadipate_6-semialdehyde_m is out of the soft bounds.
Error: Species concentration Adenosine_c is out of the hard bounds.
Collagen alpha-1(XXI) chain Protein assembly
Warning: Species concentration Malonyl-CoA_m is out of the soft bounds.
Xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming) Purine metabolism / Glutamate metabolism EC:6.3.5.2
Error: Species concentration Acyl-CoA-VLDL-SM-pool_c is out of the hard bounds.
Warning: Species concentration 4-Hydroxyphenylpyruvate_c is out of the soft bounds.
Warning: Species concentration beta-Alanine_s is out of the soft bounds.
Warning: Species concentration 5-Oxoproline_c is out of the soft bounds.
Warning: Species concentration Dihydroceramide-pool_c is out of the soft bounds.
Warning: Species concentration Mannose_s is out of the soft bounds.
Error: Species concentration 3alpha,7alpha-Dihydroxy-5beta-cholestanate_p is out of the hard bounds.
Error: Species concentration Nicotinamide_D-ribonucleotide_c is out of the hard bounds.
Warning: Species concentration 6-[(1S,2R)-1,2-Dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin_c is out of the soft bounds.
Warning: Species concentration ADP_r is out of the soft bounds.
Error: Species concentration Linolenate_c is out of the hard bounds.
Warning: Species concentration Na+_r is out of the soft bounds.
Error: Species concentration O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine_s is out of the hard bounds.
Warning: Species concentration glutathionyl-leuc4_c is out of the soft bounds.
(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl- CoA hydro-lyase Bile acid biosynthesis EC:4.2.1.107
Error: Species concentration Adenine_s is out of the hard bounds.
Error: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA_r is out of the hard bounds.
Warning: Species concentration Acetyl_adenylate_c is out of the soft bounds.
Warning: Species concentration THF-activated_formyl_group_m is out of the soft bounds.
Error: Species concentration H2O_s is out of the hard bounds.
Error: Species concentration Acetyl-CoA_m is out of the hard bounds.
Error: Species concentration UDP-activated-galactose_c is out of the hard bounds.
Error: Species concentration Taurine_c is out of the hard bounds.
Error: Species concentration 4-Methyl-2-oxopentanoate_m is out of the hard bounds.
GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing) Fructose and mannose metabolism EC:1.1.1.271
Error: Species concentration Thymine_m is out of the hard bounds.
Warning: Species concentration Na+_s is out of the soft bounds.
Nicotinamide-D-ribonucleotide amidohydrolase Nicotinate and nicotinamide metabolism EC:3.5.1.42
Warning: Species concentration D-3-Hydroxyhexanoyl-ACP_c is out of the soft bounds.
Error: Species concentration O2.-_s is out of the hard bounds.
Warning: Species concentration Acetaldehyde_c is out of the soft bounds.
Error: Species concentration Fatty-acid-VLDL-PI-pool_c is out of the hard bounds.
ATP-binding Cassette (ABC) TCDB:3.A.1.204.5
Error: Species concentration Hexadecanoyl-ACP_c is out of the hard bounds.
Error: Species concentration 3-Oxopropanoate_m is out of the hard bounds.
Warning: Species concentration Malonyl-CoA_r is out of the soft bounds.
Warning: Species concentration prostaglandin-c2_c is out of the soft bounds.
Warning: Species concentration 2-Methylacetoacetyl-CoA_m is out of the soft bounds.
Warning: Species concentration sulfotaurolithocholate_c is out of the soft bounds.
Error: Species concentration Malonyl-Carnitin_c is out of the hard bounds.
Error: Species concentration UDP-activated-N-acetyl-D-galactosamine_c is out of the hard bounds.
Warning: Species concentration (R)-5-Diphosphomevalonate_p is out of the soft bounds.
Warning: Species concentration Adenosine_m is out of the soft bounds.
Warning: Species concentration Methanol_c is out of the soft bounds.
Warning: Species concentration 1-Acylglycerol-3P-VLDL-PE-pool_c is out of the soft bounds.
Warning: Species concentration L-Oleoylcarnitine_c is out of the soft bounds.
Error: Species concentration Formate_c is out of the hard bounds.
Warning: Species concentration K+_c is out of the soft bounds.
Warning: Species concentration prostaglandin-f2alpha_s is out of the soft bounds.
Error: Species concentration (R)-3-Hydroxybutanoate_m is out of the hard bounds.
Warning: Species concentration Ceramide-pool_c is out of the soft bounds.
Warning: Species concentration THF_c is out of the soft bounds.
Warning: Species concentration Collagen_CO8A1_c is out of the soft bounds.
Warning: Species concentration 3PG_m is out of the soft bounds.
Warning: Species concentration Formaldehyde_c is out of the soft bounds.
Error: Species concentration Taurocholate_s is out of the hard bounds.
Warning: Species concentration Ethanol_s is out of the soft bounds.
Warning: Species concentration prostaglandin-a2_c is out of the soft bounds.
Warning: Species concentration Collagen_COOA1_c is out of the soft bounds.
Error: Species concentration Deoxyuridine_c is out of the hard bounds.
Error: Species concentration (S)-3-Hydroxybutyryl-CoA_m is out of the hard bounds.
Error: Species concentration CDP_c is out of the hard bounds.
Warning: Species concentration Isopentenyl-PP_p is out of the soft bounds.
Error: Species concentration Cholesterol_l is out of the hard bounds.
Error: Species concentration CMP-N-acetylneuraminate_n is out of the hard bounds.
Error: Species concentration Tiglyl-CoA_m is out of the hard bounds.
Error: Species concentration Collagen_COFA1_c is out of the hard bounds.
CDPcholine:N-acylsphingosine cholinephosphotransferase Sphingolipid metabolism EC:2.7.8.3
Error: Species concentration Sulfate_s is out of the hard bounds.
Error: Species concentration Oxidized_thioredoxin_c is out of the hard bounds.
Warning: Species concentration Dimethylallyl-PP_p is out of the soft bounds.
Error: Species concentration Malonate_m is out of the hard bounds.
Xanthine:oxygen oxidoreductase Purine metabolism EC:1.17.3.2
Error: Species concentration Inositol_c is out of the hard bounds.
Error: Species concentration 1-Acylglycerol-3P-ol_c is out of the hard bounds.
Warning: Species concentration PAP_c is out of the soft bounds.
Divalent Anion:Na$^{+}$ Symporter (DASS) TCDB:2.A.47.1.4
Error: Species concentration Arachidonate_l is out of the hard bounds.
Superoxide:superoxide oxidoreductase EC:1.15.1.1
Warning: Species concentration Ornithine_c is out of the soft bounds.
Warning: Species concentration GTP_m is out of the soft bounds.
Error: Species concentration Sedoheptulose-1,7PP_c is out of the hard bounds.
Error: Species concentration Collagen_CO6A2_c is out of the hard bounds.
Error: Species concentration Ethanolamine_c is out of the hard bounds.
Error: Species concentration Valine_s is out of the hard bounds.
Warning: Species concentration L-Carnitine_m is out of the soft bounds.
Warning: Species concentration Folate_m is out of the soft bounds.
Error: Species concentration (2E)-Dodecenoyl-CoA_m is out of the hard bounds.
Warning: Species concentration Dopamine_b is out of the soft bounds.
Error: Species concentration Decanoyl-ACP_c is out of the hard bounds.
Propanoyl-CoA:acetyl-CoA C-acyltransferase Valine, leucine and isoleucine degradation EC:2.3.1.16
Warning: Species concentration L-Lactate_m is out of the soft bounds.
Warning: Species concentration Ferricytochrome_C_m is out of the soft bounds.
5-Phosphoribosylamine:pyrophosphate phosphoribosyltransferase (glutamate-amidating) Purine metabolism / Glutamate metabolism EC:2.4.2.14
Error: Species concentration dTMP_c is out of the hard bounds.
Warning: Species concentration Collagen_CD36_c is out of the soft bounds.
Warning: Species concentration L-Octanoylcarnitine_p is out of the soft bounds.
Error: Species concentration D-Xylulose-5P_c is out of the hard bounds.
Warning: Species concentration Urate_s is out of the soft bounds.
Warning: Species concentration prostaglandin-c1_s is out of the soft bounds.
Error: Species concentration (S)-3-Hydroxytetradecanoyl-CoA_p is out of the hard bounds.
Warning: Species concentration UroporphyrinogenIII_c is out of the soft bounds.
L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating) Phenylalanine, tyrosine and tryptophan biosynthesis EC:1.14.16.1
Warning: Species concentration Pyridoxine_c is out of the soft bounds.
Error: Species concentration Pantothenate_s is out of the hard bounds.
Error: Species concentration H2O2_s is out of the hard bounds.
Warning: Species concentration CO2_c is out of the soft bounds.
D-Fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase Fructose and mannose metabolism EC:4.1.2.13
Warning: Species concentration AKG_s is out of the soft bounds.
Error: Species concentration CoproporphyrinogenI_s is out of the hard bounds.
Warning: Species concentration gamma-Linolenoyl-CoA_c is out of the soft bounds.
NADPH:CoA-glutathione oxidoreductase EC:1.8.1.9
ATP:cytidine 5'-phosphotransferase Pyrimidine metabolism EC:2.7.1.48
Warning: Species concentration PE-VLDL-pool_r is out of the soft bounds.
Error: Species concentration UMP_s is out of the hard bounds.
Warning: Species concentration Collagen_CO9A2_c is out of the soft bounds.
Warning: Species concentration L-Palmitoylcarnitine_r is out of the soft bounds.
Warning: Species concentration GSSG_c is out of the soft bounds.
Warning: Species concentration prostaglandin-b1_s is out of the soft bounds.
Warning: Species concentration Fatty-acid-VLDL-PC-pool_r is out of the soft bounds.
3,4-Dihydroxymandelaldehyde:NADP+ oxidoreductase Tyrosine metabolism EC:1.2.1.5
ATP:adenosine 5'-phosphotransferase Purine metabolism EC:2.7.1.20
Warning: Species concentration Hydroxymethylglutathione_c is out of the soft bounds.
Warning: Species concentration 2-Methylbutyryl-CoA_m is out of the soft bounds.
Warning: Species concentration CoA-activated_acetyl_group_m is out of the soft bounds.
Warning: Species concentration ATP_c is out of the soft bounds.
Error: Species concentration Glucosamine-6P_c is out of the hard bounds.
Error: Species concentration NADPH-redox-potential_c is out of the hard bounds.
Error: Species concentration Palmitolate_s is out of the hard bounds.
Warning: Species concentration Isoleucine_l is out of the soft bounds.
Error: Species concentration Myristoyl-CoA_p is out of the hard bounds.
Warning: Species concentration Valine_m is out of the soft bounds.
Cholate:CoA ligase (AMP-forming) Bile acid biosynthesis EC:6.2.1.7
3-Ureidoisobutyrate amidohydrolase Pyrimidine metabolism EC:3.5.1.6
Warning: Species concentration UMP_r is out of the soft bounds.
Error: Species concentration Maltose_s is out of the hard bounds.
Error: Species concentration Linoleate_c is out of the hard bounds.
Error: Species concentration Bile-PC-pool_b is out of the hard bounds.
Warning: Species concentration Deoxyguanosine_s is out of the soft bounds.
2-Deoxy-D-ribose-5-phosphate acetaldehyde-lyase Pentose phosphate pathway EC:4.1.2.4
Warning: Species concentration UDP-xylose_c is out of the soft bounds.
Error: Species concentration Proton-gradient_m is out of the hard bounds.
Warning: Species concentration H2O_p is out of the soft bounds.
Error: Species concentration (2E)-Hexadecenoyl-CoA_p is out of the hard bounds.
Error: Species concentration O-Acetylcarnitine_r is out of the hard bounds.
Warning: Species concentration (2E)-Octadecenoyl-ACP_c is out of the soft bounds.
Pyruvate:carbon-dioxide ligase (ADP-forming) Citrate cycle (TCA cycle) EC:6.4.1.1
Warning: Species concentration NADH-redox-potential_p is out of the soft bounds.
Warning: Species concentration prostaglandin-d3_c is out of the soft bounds.
Warning: Species concentration Histamine_b is out of the soft bounds.
Warning: Species concentration Adenine_s is out of the soft bounds.
Warning: Species concentration Palmitate_r is out of the soft bounds.
Warning: Species concentration Acyl-CoA-VLDL-PI-pool_c is out of the soft bounds.
Warning: Species concentration Triiodothyronine_c is out of the soft bounds.
Warning: Species concentration Collagen_CO1A2_c is out of the soft bounds.
Warning: Species concentration Citrulline_m is out of the soft bounds.
Error: Species concentration 1-Acylglycerol-VLDL-SM-pool_c is out of the hard bounds.
Warning: Species concentration N-(omega)-Hydroxyarginine_c is out of the soft bounds.
Warning: Species concentration PS-VLDL-pool_l is out of the soft bounds.
Warning: Species concentration LacCer-pool_r is out of the soft bounds.
Warning: Species concentration (2E)-Tetradecenoyl-CoA_p is out of the soft bounds.
Warning: Species concentration Threonine_s is out of the soft bounds.
Warning: Species concentration 1,2-Diacylglycerol-VLDL-PC-pool_c is out of the soft bounds.
Warning: Species concentration CDP-diacylglycerol-CL-pool_m is out of the soft bounds.
Error: Species concentration O2.-_c is out of the hard bounds.
Error: Species concentration Acetate_s is out of the hard bounds.
Error: Species concentration Acetyl-CoA_r is out of the hard bounds.
Warning: Species concentration N-Acetylglucosamine_l is out of the soft bounds.
Carbon-dioxide:ammonia ligase (ADP-forming,carbamate-phosphorylating) Urea cycle and metabolism of amino groups / Nitrogen metabolism EC:6.3.4.16
Warning: Species concentration PRPP_s is out of the soft bounds.
Warning: Species concentration Taurochenodeoxycholate_s is out of the soft bounds.
Error: Species concentration Propanoate_s is out of the hard bounds.
Warning: Species concentration Arachidonyl-CoA_p is out of the soft bounds.
Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming) Pentose and glucuronate interconversions EC:1.1.1.10
(R)-3-Hydroxybutanoate:NAD+ oxidoreductase Synthesis and degradation of ketone bodies / Butanoate metabolism EC:1.1.1.30
ATP:deoxyadenosine 5'-phosphotransferase Purine metabolism EC:2.7.1.76
Error: Species concentration sulfoglycolithocholate_c is out of the hard bounds.
Warning: Species concentration Acyl-CoA-CL-pool_m is out of the soft bounds.
Error: Species concentration ApoE_r is out of the hard bounds.
Error: Species concentration (2E)-Decenoyl-CoA_p is out of the hard bounds.
Cation-Chloride Cotransporter (CCC) TCDB:2.A.30.3.1
Warning: Species concentration lithocholate_s is out of the soft bounds.
Error: Species concentration Cholesterol-ester-palm_r is out of the hard bounds.
Warning: Species concentration Arachidonyl-Carnitine_c is out of the soft bounds.
Error: Species concentration UDP-activated-xylose_c is out of the hard bounds.
N-[(R)-4'-Phosphopantothenoyl]-L-cysteine carboxy-lyase Pantothenate and CoA biosynthesis EC:4.1.1.36
ATP:L-methione S-adenosyltransferase Methionine metabolism EC:2.5.1.6
Warning: Species concentration Isoleucine_c is out of the soft bounds.
Warning: Species concentration prostaglandin-f1alpha_s is out of the soft bounds.
Error: Species concentration 5-Formiminotetrahydrofolate_c is out of the hard bounds.
L-threonine ammonia-lyase Glycine, serine and threonine metabolism / Valine, leucine and isoleucine biosynthesis EC:4.3.1.19
Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) Tyrosine metabolism / Styrene degradation EC:1.13.11.5
Warning: Species concentration Pyridoxal_c is out of the soft bounds.
Error: Species concentration Collagen_CO5A1_c is out of the hard bounds.
Error: Species concentration Acetoacetyl-CoA_m is out of the hard bounds.
Error: Species concentration 3-Oxotetradecanoyl-ACP_c is out of the hard bounds.
Error: Species concentration dUTP_m is out of the hard bounds.
Lactose 6-phosphate galactohydrolase Galactose metabolism EC:3.2.1.23
Warning: Species concentration H+(PG)_c is out of the soft bounds.
Error: Species concentration Inosine_s is out of the hard bounds.
Error: Species concentration Sphinganine_c is out of the hard bounds.
alpha,alpha-Trehalose glucohydrolase Starch and sucrose metabolism EC:3.2.1.28
Warning: Species concentration 7alpha,12alpha-Dihydroxycholest-4-en-3-one_c is out of the soft bounds.
L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) Tryptophan metabolism EC:1.13.11.11
Glutaryl-CoA:dihydrolipoamide S-succinyltransferase Lysine degradation EC:2.3.1.61
Isomaltose 6-alpha-D-glucanohydrolase Starch and sucrose metabolism EC:3.2.1.10
GTP:oxaloacetate carboxy-lyase (transphosphorylating) Citrate cycle (TCA cycle) / Pyruvate metabolism EC:4.1.1.32
Warning: Species concentration Plasminogen_c is out of the soft bounds.
Error: Species concentration N-Acetylmannosamine-6P_c is out of the hard bounds.
Warning: Species concentration Glucose-6P_r is out of the soft bounds.
(S)-Hydroxyhexanoyl-CoA hydro-lyase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:4.2.1.17
Error: Species concentration 2-Oxoadipate_m is out of the hard bounds.
L-2-Aminoadipate:2-oxoglutarate aminotransferase Lysine biosynthesis / Lysine degradation EC:2.6.1.39
Error: Species concentration PC-VLDL-pool_c is out of the hard bounds.
Error: Species concentration 3alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-CoA_p is out of the hard bounds.
Warning: Species concentration IDP_s is out of the soft bounds.
3-hydroxyisobutyryl-CoA hydrolase beta-Alanine metabolism / Propanoate metabolism EC:3.1.2.4
Warning: Species concentration 2-Hydroxybutyrate_s is out of the soft bounds.
Warning: Species concentration Collagen_CO4A1_c is out of the soft bounds.
Warning: Species concentration Erythrose-4P_c is out of the soft bounds.
Warning: Species concentration glutathionyl-leuc4_b is out of the soft bounds.
Error: Species concentration Galactose_s is out of the hard bounds.
Warning: Species concentration Antitrypsin_l is out of the soft bounds.
Warning: Species concentration 3-Oxodecanoyl-ACP_c is out of the soft bounds.
Warning: Species concentration Saccharopine_m is out of the soft bounds.
sn-Glycerol-3-phosphate:(acceptor) 2-oxidoreductase Glycerophospholipid metabolism EC:1.1.5.3
Warning: Species concentration Haptoglobin_s is out of the soft bounds.
collagen, type XIV, alpha 1 Protein assembly
Warning: Species concentration (2E)-Hexenoyl-CoA_m is out of the soft bounds.
Error: Species concentration Mercaptopyruvate_c is out of the hard bounds.
Amino Acid-Polyamine-Organocation (APC) TCDB:2.A.3.8.5
Error: Species concentration 3alpha,7alpha,12alpha-Trihydroxycoprostane_c is out of the hard bounds.
Warning: Species concentration Adenine_c is out of the soft bounds.
Error: Species concentration THF-activated_methylene_group_m is out of the hard bounds.
Error: Species concentration 2-Aminoadipate_6-semialdehyde_m is out of the hard bounds.
Warning: Species concentration ADP_p is out of the soft bounds.
Warning: Species concentration gamma-Glutamyl-beta-cyanoalanine_s is out of the soft bounds.
Warning: Species concentration Formylanthranilate_c is out of the soft bounds.
Warning: Species concentration Lauroyl-CoA_m is out of the soft bounds.
Error: Species concentration THF-activated_formyl_group_m is out of the hard bounds.
Error: Species concentration prostaglandin-i2_c is out of the hard bounds.
Warning: Species concentration Ascorbate_s is out of the soft bounds.
3-methyl-2-oxobutanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating) EC:1.2.4.4
Error: Species concentration CO2_r is out of the hard bounds.
Acetyl-CoA:acetyl-CoA C-acetyltransferase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:2.3.1.16
Warning: Species concentration 3alpha,7alpha-Dihydroxy-5beta-cholestanate_c is out of the soft bounds.
IMP:NAD+ oxidoreductase Purine metabolism EC:1.1.1.205
Error: Species concentration UDP_r is out of the hard bounds.
Warning: Species concentration 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA_p is out of the soft bounds.
Error: Species concentration Bilirubin-monoglucuronoside_c is out of the hard bounds.
(S)-3-Hydroxybutanoyl-CoA hydro-lyase Fatty acid metabolism / Lysine degradation / Tryptophan metabolism / Benzoate degradation via CoA ligation / Butanoate metabolism EC:4.2.1.17
2'-Deoxyadenosine 5'-monophosphate phosphohydrolase Purine metabolism EC:3.1.3.5
Error: Species concentration Retinoate_c is out of the hard bounds.
Error: Species concentration 2-Lysolecithin-pool_c is out of the hard bounds.
3-Hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing) Tryptophan metabolism EC:1.13.11.6
Inosine 5'-monophosphate phosphohydrolase Purine metabolism EC:3.1.3.5
Error: Species concentration (2E)-Dodecenoyl-ACP_c is out of the hard bounds.
dodecanoyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) Fatty acid biosynthesis EC:2.3.1.85
Warning: Species concentration Hydroxymethylbilane_c is out of the soft bounds.
Warning: Species concentration O2.-_c is out of the soft bounds.
Error: Species concentration Malonyl-Carnitin_m is out of the hard bounds.
glucan (1,4-alpha-), branching enzyme 1 EC:2.4.1.18
Warning: Species concentration Fibrinogen_s is out of the soft bounds.
4-Maleylacetoacetate cis-trans-isomerase Tyrosine metabolism / Styrene degradation EC:5.2.1.2
Error: Species concentration Acetaldehyde_c is out of the hard bounds.
Warning: Species concentration 2-Methyl-3-oxopropanoate_m is out of the soft bounds.
Warning: Species concentration AKG_p is out of the soft bounds.
Error: Species concentration prostaglandin-c2_c is out of the hard bounds.
Warning: Species concentration Arachidonate_p is out of the soft bounds.
Warning: Species concentration Phosphatidate-VLDL-TG-pool_c is out of the soft bounds.
3-Methylbutanoyl-CoA:(acceptor) 2,3-oxidoreductase Valine, leucine and isoleucine degradation EC:1.3.99.10
Warning: Species concentration Arachidonyl-CoA_r is out of the soft bounds.
Warning: Species concentration PS-VLDL-pool_b is out of the soft bounds.
Error: Species concentration (R)-5-Diphosphomevalonate_p is out of the hard bounds.
Warning: Species concentration 7alpha-Hydroxycholest-4-en-3-one_c is out of the soft bounds.
Error: Species concentration Dehydroepiandrosterone_sulfate_s is out of the hard bounds.
Error: Species concentration Glucono-1,5-lactone-6P_r is out of the hard bounds.
Warning: Species concentration Uracil_s is out of the soft bounds.
Warning: Species concentration Pi_m is out of the soft bounds.
Error: Species concentration gamma-Glutamyl-cysteine_c is out of the hard bounds.
Error: Species concentration Choline_s is out of the hard bounds.
Warning: Species concentration Collagen_CTHR1_c is out of the soft bounds.
Warning: Species concentration Acetoacetyl-ACP_c is out of the soft bounds.
Error: Species concentration 2-Oxo-3-methylvalerate_m is out of the hard bounds.
Error: Species concentration Presqualene-PP_r is out of the hard bounds.
Warning: Species concentration S-glutathionyl-2-4-dinitrobenzene_b is out of the soft bounds.
Warning: Species concentration Oleate_s is out of the soft bounds.
Error: Species concentration PPi_p is out of the hard bounds.
Error: Species concentration Tyrosine_m is out of the hard bounds.
Warning: Species concentration Leukotriene_C4_c is out of the soft bounds.
Error: Species concentration (S)-3-Hydroxydodecanoyl-CoA_m is out of the hard bounds.
Error: Species concentration 3PG_m is out of the hard bounds.
Error: Species concentration Leukotriene_C4_s is out of the hard bounds.
Warning: Species concentration Taurocholate_c is out of the soft bounds.
Error: Species concentration Carbamoyl-P_m is out of the hard bounds.
Warning: Species concentration Hypotaurine_c is out of the soft bounds.
Error: Species concentration Collagen_COOA1_c is out of the hard bounds.
Pyridoxamine-5'-phosphate:oxygen oxidoreductase (deaminating) Vitamin B6 metabolism EC:1.4.3.5
Hexanoyl-[acyl-carrier protein]:oxoacyl- and enoyl-reducing and thioester-hydrolysing) Fatty acid biosynthesis EC:2.3.1.85
Warning: Species concentration Malonyl-Carnitin_r is out of the soft bounds.
Error: Species concentration Sphinganine-1P_c is out of the hard bounds.
Error: Species concentration Isopentenyl-PP_p is out of the hard bounds.
S-Adenosyl-L-methionine:methylethanolamine phosphate N-methyltransferase Glycerophospholipid metabolism EC:2.1.1.103
Warning: Species concentration NADPH-redox-potential_p is out of the soft bounds.
Error: Species concentration 6-Deoxy-L-galactose_c is out of the hard bounds.
Error: Species concentration dTMP_s is out of the hard bounds.
Warning: Species concentration Chenodiol_s is out of the soft bounds.
Error: Species concentration Palmitate_l is out of the hard bounds.
Warning: Species concentration NADH_m is out of the soft bounds.
Error: Species concentration Acyl-CoA-VLDL-PC-pool_c is out of the hard bounds.
Error: Species concentration L-Oleoylcarnitine_c is out of the hard bounds.
Warning: Species concentration Sulfate_c is out of the soft bounds.
Warning: Species concentration prostaglandin-b2_s is out of the soft bounds.
Warning: Species concentration Stearoyl-CoA_r is out of the soft bounds.
Warning: Species concentration Lathosterol_r is out of the soft bounds.
Warning: Species concentration Leucine_c is out of the soft bounds.
Error: Species concentration Ethanol_c is out of the hard bounds.
Error: Species concentration FAD_m is out of the hard bounds.
Error: Species concentration Collagen_COKA1_c is out of the hard bounds.
Error: Species concentration gamma-Linolenate_c is out of the hard bounds.
Warning: Species concentration NO_s is out of the soft bounds.
Warning: Species concentration glycolithocholate_s is out of the soft bounds.
Warning: Species concentration Threonine_m is out of the soft bounds.
Error: Species concentration Glucosamine_c is out of the hard bounds.
Warning: Species concentration 5-Phosphoribosylamine_c is out of the soft bounds.
Error: Species concentration Folate_m is out of the hard bounds.
Warning: Species concentration 5alpha-Cholesta-7,24-dien-3beta-ol_r is out of the soft bounds.
Warning: Species concentration Acetoacetate_c is out of the soft bounds.
Error: Species concentration 1-Acylglycerol-3P-arach_c is out of the hard bounds.
Warning: Species concentration Guanosine_c is out of the soft bounds.
Warning: Species concentration D-Tagatose-6P_c is out of the soft bounds.
D-Glucose-6-phosphate:NADP+ 1-oxoreductase EC:1.1.1.49
Warning: Species concentration prostaglandin-e1_s is out of the soft bounds.
Warning: Species concentration dTDP_s is out of the soft bounds.
Warning: Species concentration Malate_c is out of the soft bounds.
Warning: Species concentration Butyrate_c is out of the soft bounds.
Carbon-dioxide:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) Pyrimidine metabolism / Glutamate metabolism EC:6.3.5.5
Warning: Species concentration NH3_c is out of the soft bounds.
ATP:sulfate adenylyltransferase Purine metabolism / Sulfur metabolism EC:2.7.7.4
3alpha,7alpha-Dihydroxy-5beta-cholestane:NADP+ oxidoreductase (B-specific); 3alpha,7alpha-Dihydroxy-5beta-cholestane:NADP+ oxidoreductase Bile acid biosynthesis EC:1.1.1.50
GDPmannose 4,6-hydro-lyase Fructose and mannose metabolism EC:4.2.1.47
Warning: Species concentration Arachidonyl-Carnitine_p is out of the soft bounds.
Warning: Species concentration SM-pool_c is out of the soft bounds.
Warning: Species concentration Pantothenate_c is out of the soft bounds.
L-2-Aminoadipate-6-semialdehyde:NAD+ 6-oxidoreductase Lysine degradation EC:1.2.1.31
Error: Species concentration CO2_c is out of the hard bounds.
Error: Species concentration Glycerol_m is out of the hard bounds.
Warning: Species concentration Hexanoyl-ACP_c is out of the soft bounds.
5-Formyltetrahydrofolate cyclo-ligase (ADP-forming) One carbon pool by folate EC:6.3.3.2
GDP phosphohydrolase Purine metabolism EC:3.6.1.6 EC:3.6.1.42
Warning: Species concentration Quinolinate_c is out of the soft bounds.
Warning: Species concentration Apo-ACP_c is out of the soft bounds.
Carbamoyl-phosphate:L-aspartate carbamoyltransferase Pyrimidine metabolism / Alanine and aspartate metabolism EC:2.1.3.2
Warning: Species concentration 1-Acylglycerol-3P-arach_c is out of the soft bounds.
Warning: Species concentration Fructose-6P_c is out of the soft bounds.
Error: Species concentration L-Palmitoylcarnitine_r is out of the hard bounds.
Warning: Species concentration Taurochenodeoxycholate_b is out of the soft bounds.
Error: Species concentration Phenylalanine_s is out of the hard bounds.
Warning: Species concentration Palmitoyl-CoA_r is out of the soft bounds.
Warning: Species concentration Thioredoxin-redox-potential_c is out of the soft bounds.
Error: Species concentration Arginine_s is out of the hard bounds.
Error: Species concentration Dihydrofolate_m is out of the hard bounds.
L-Histidine ammonia-lyase Histidine metabolism / Nitrogen metabolism EC:4.3.1.3
Error: Species concentration Farnesyl-PP_p is out of the hard bounds.
Warning: Species concentration D-3-Amino-isobutanoate_m is out of the soft bounds.
Error: Species concentration Albumin_c is out of the hard bounds.
3-hydroxypropanoate:NAD+ oxidoreductase beta-Alanine metabolism / Propanoate metabolism EC:1.1.1.59
Error: Species concentration dGTP_s is out of the hard bounds.
Error: Species concentration Collagen_CO6A6_c is out of the hard bounds.
Error: Species concentration Chitobiose_l is out of the hard bounds.
Warning: Species concentration O2_p is out of the soft bounds.
Error: Species concentration Collagen_CORA1_c is out of the hard bounds.
Error: Species concentration Cystine_c is out of the hard bounds.
Error: Species concentration Chenodeoxycholoyl-CoA_r is out of the hard bounds.
Error: Species concentration Valine_m is out of the hard bounds.
Warning: Species concentration Acetone_m is out of the soft bounds.
Error: Species concentration 1-Acylglycerol-3P-VLDL-PI-pool_c is out of the hard bounds.
Octanoyl-CoA:L-carnitine O-octanoyltransferase EC:2.3.1.137
Warning: Species concentration Isoleucine_s is out of the soft bounds.
L-Serine:pyruvate aminotransferase Glycine, serine and threonine metabolism EC:2.6.1.51
Warning: Species concentration Asparagine_m is out of the soft bounds.
collagen, type XI, alpha 2 Protein assembly
Warning: Species concentration Estrone_3-sulfate_s is out of the soft bounds.
Error: Species concentration PE-VLDL-pool_c is out of the hard bounds.
Warning: Species concentration Collagen_CO5A2_c is out of the soft bounds.
Warning: Species concentration Sphingosine-1P_c is out of the soft bounds.
Error: Species concentration GSH_s is out of the hard bounds.
Error: Species concentration L-Palmitoylcarnitine_m is out of the hard bounds.
Warning: Species concentration Ribulose-5P_c is out of the soft bounds.
N-acylsphingosine amidohydrolase Sphingolipid metabolism EC:3.5.1.23
Error: Species concentration PPi_m is out of the hard bounds.
Error: Species concentration Citrulline_m is out of the hard bounds.
Warning: Species concentration 1-Acylglycerol-VLDL-PI-pool_c is out of the soft bounds.
Error: Species concentration N-(omega)-Hydroxyarginine_c is out of the hard bounds.
Warning: Species concentration Dihomo-gamma-linolenoyl-CoA_r is out of the soft bounds.
Warning: Species concentration Dopamine_s is out of the soft bounds.
Error: Species concentration PS-VLDL-pool_l is out of the hard bounds.
Succinate:CoA ligase (GDP-forming) Citrate cycle (TCA cycle) / Propanoate metabolism EC:6.2.1.4
Error: Species concentration UTP_s is out of the hard bounds.
Error: Species concentration H2O_m is out of the hard bounds.
Warning: Species concentration Ferrocytochrome_b5_c is out of the soft bounds.
Error: Species concentration NADH-redox-potential_p is out of the hard bounds.
Error: Species concentration NADPH_r is out of the hard bounds.
Error: Species concentration prostaglandin-d3_s is out of the hard bounds.
1-(5-Phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming) Purine metabolism EC:6.3.2.6
Error: Species concentration Xanthine_c is out of the hard bounds.
Collagen alpha-3(IX) chain Protein assembly
Acetyl-CoA:propanoate CoA-transferase Propanoate metabolism EC:2.3.1.15
Ribitol:NAD+ 2-oxidoreductase Pentose and glucuronate interconversions EC:1.1.1.56
Error: Species concentration H2S_s is out of the hard bounds.
Error: Species concentration IDP_c is out of the hard bounds.
Cholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) Bile acid biosynthesis EC:1.14.13.17
Succinate:ubiquinone oxidoreductase Citrate cycle (TCA cycle) EC:1.3.5.1
Warning: Species concentration AMP_m is out of the soft bounds.
Warning: Species concentration Arachidonate_c is out of the soft bounds.
Error: Species concentration Tyrosine_s is out of the hard bounds.
Error: Species concentration dATP_c is out of the hard bounds.
Warning: Species concentration GDP_m is out of the soft bounds.
Warning: Species concentration activated-sulphur_c is out of the soft bounds.
L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating) Tryptophan metabolism EC:1.14.16.4
Warning: Species concentration Dihomo-gamma-linolenate_c is out of the soft bounds.
Error: Species concentration ATP_c is out of the hard bounds.
Warning: Species concentration dTDP_c is out of the soft bounds.
Warning: Species concentration glycoursodeoxycholate_s is out of the soft bounds.
Warning: Species concentration Betaine_aldehyde_c is out of the soft bounds.
S-Adenosyl-L-homocysteine hydrolase Methionine metabolism EC:3.3.1.1
Error: Species concentration Dihydroceramide-pool_c is out of the hard bounds.
Error: Species concentration Leucine_c is out of the hard bounds.
Error: Species concentration 6-[(1S,2R)-1,2-Dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin_c is out of the hard bounds.
CoA:apo-[acyl-carrier-protein] pantetheinephosphotransferase Pantothenate and CoA biosynthesis EC:2.7.8.7
2'-Deoxycytidine 5'-monophosphate phosphohydrolase Pyrimidine metabolism EC:3.1.3.5
Warning: Species concentration Octanoyl-ACP_c is out of the soft bounds.
Error: Species concentration Na+_r is out of the hard bounds.
Warning: Species concentration PG-CL-pool_m is out of the soft bounds.
Error: Species concentration PC-VLDL-pool_l is out of the hard bounds.
Error: Species concentration Cholesterol-ester-ol_r is out of the hard bounds.
Warning: Species concentration (S)-3-Hydroxytetradecanoyl-CoA_m is out of the soft bounds.
Error: Species concentration Antichymotrypsin_s is out of the hard bounds.
Warning: Species concentration PI-pool_r is out of the soft bounds.
5'-Methylthioadenosine:orthophosphate methylthio-D-ribosyltransferase Methionine metabolism EC:2.4.2.28
Error: Species concentration 4-Aminobutanal_m is out of the hard bounds.
L-Glutamine:pyruvate aminotransferase Glutamate metabolism EC:2.6.1.15
Error: Species concentration 7alpha,12alpha-Dihydroxycholest-4-en-3-one_c is out of the hard bounds.
Warning: Species concentration Thymine_s is out of the soft bounds.
Warning: Species concentration DHAP_s is out of the soft bounds.
Error: Species concentration O2_p is out of the hard bounds.
Warning: Species concentration Aspartate_c is out of the soft bounds.
Error: Species concentration D-3-Hydroxyhexanoyl-ACP_c is out of the hard bounds.
Warning: Species concentration Isocitrate_m is out of the soft bounds.
Warning: Species concentration Inosine_c is out of the soft bounds.
Warning: Species concentration Glucose_s is out of the soft bounds.
Warning: Species concentration Alanine_c is out of the soft bounds.
N6-(L-1,3-Dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming) Lysine biosynthesis / Lysine degradation EC:1.5.1.8
Warning: Species concentration 2-Oxoadipate_c is out of the soft bounds.
Error: Species concentration 2-Hydroxybutyrate_s is out of the hard bounds.
Warning: Species concentration (2E)-Hexadecenoyl-ACP_c is out of the soft bounds.
Error: Species concentration L-Cystathionine_c is out of the hard bounds.
Error: Species concentration Glutaryl-CoA_m is out of the hard bounds.
Error: Species concentration glutathionyl-leuc4_b is out of the hard bounds.
Error: Species concentration Spermidine_s is out of the hard bounds.
Warning: Species concentration Glucosamine-6P_c is out of the soft bounds.
Warning: Species concentration 5beta-Cholestane-3alpha,7alpha,12alpha,26-tetrol_m is out of the soft bounds.
Error: Species concentration NADP+_p is out of the hard bounds.
Error: Species concentration Glutamine_m is out of the hard bounds.
Error: Species concentration THF_c is out of the hard bounds.
Warning: Species concentration 7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one_c is out of the soft bounds.
Error: Species concentration Collagen_CO8A1_c is out of the hard bounds.
Error: Species concentration L-Lactate_s is out of the hard bounds.
Warning: Species concentration 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA_p is out of the soft bounds.
Warning: Species concentration Taurocholate_b is out of the soft bounds.
Warning: Species concentration DHAP_p is out of the soft bounds.
(3R)-3-Hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase; (3R)-3-Hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase Fatty acid biosynthesis EC:2.3.1.85
Warning: Species concentration FADH2_m is out of the soft bounds.
Warning: Species concentration CMP-N-acetylneuraminate_c is out of the soft bounds.
Error: Species concentration Pantothenate_c is out of the hard bounds.
Warning: Species concentration reverse-triiodthyronine_s is out of the soft bounds.
Warning: Species concentration Thioredoxin_c is out of the soft bounds.
Error: Species concentration Proton-gradient_c is out of the hard bounds.
Warning: Species concentration prostaglandin-d2_c is out of the soft bounds.
Error: Species concentration Fe2+_m is out of the hard bounds.
Warning: Species concentration Squalene_r is out of the soft bounds.
2-methylpropanoyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-(2-methylpropanoyl)transferase Valine, leucine and isoleucine degradation EC:2.3.1.168
Warning: Species concentration Propanoyl-CoA_m is out of the soft bounds.
Warning: Species concentration Asparagine_c is out of the soft bounds.
Error: Species concentration Arginine_m is out of the hard bounds.
Error: Species concentration S-glutathionyl-2-4-dinitrobenzene_s is out of the hard bounds.
Warning: Species concentration 1,3DPG_c is out of the soft bounds.
Warning: Species concentration Palmitoyl-CoA_p is out of the soft bounds.
Error: Species concentration Cysteine_m is out of the hard bounds.
Warning: Species concentration Malonyl-Carnitin_c is out of the soft bounds.
Error: Species concentration Lysine_s is out of the hard bounds.
Warning: Species concentration Farnesyl-PP_r is out of the soft bounds.
Error: Species concentration Deoxycytidine_s is out of the hard bounds.
Warning: Species concentration Valine_c is out of the soft bounds.
Warning: Species concentration dGTP_c is out of the soft bounds.
Error: Species concentration 3-Ureidoisobutyrate_c is out of the hard bounds.
Warning: Species concentration Decanoyl-CoA_m is out of the soft bounds.
Warning: Species concentration (2E)-Decenoyl-ACP_c is out of the soft bounds.
Error: Species concentration Ferricytochrome_C_m is out of the hard bounds.
Warning: Species concentration Dehydroepiandrosterone_sulfate_c is out of the soft bounds.
Warning: Species concentration Serotonin_s is out of the soft bounds.
Error: Species concentration Collagen_CD36_c is out of the hard bounds.
Error: Species concentration Urea_m is out of the hard bounds.
Error: Species concentration (S)-Hydroxyhexanoyl-CoA_m is out of the hard bounds.
Error: Species concentration Linolenate_s is out of the hard bounds.
Error: Species concentration prostaglandin-d2_s is out of the hard bounds.
Error: Species concentration Collagen_CTHR1_c is out of the hard bounds.
Error: Species concentration Thiamin_c is out of the hard bounds.
Error: Species concentration S-glutathionyl-2-4-dinitrobenzene_b is out of the hard bounds.
Error: Species concentration UroporphyrinogenIII_c is out of the hard bounds.
Error: Species concentration prostaglandin-c1_s is out of the hard bounds.
Error: Species concentration Oleate_s is out of the hard bounds.
Error: Species concentration Pyridoxine_c is out of the hard bounds.
Error: Species concentration L-Glutamate_5-semialdehyde_m is out of the hard bounds.
Warning: Species concentration Tyrosine_l is out of the soft bounds.
Error: Species concentration Pi_c is out of the hard bounds.
Collagen alpha-6(VI) chain Protein assembly
Error: Species concentration GM1-pool_s is out of the hard bounds.
Error: Species concentration PS-VLDL-pool_r is out of the hard bounds.
Warning: Species concentration (R)-5-Phosphomevalonate_p is out of the soft bounds.
Error: Species concentration PE-VLDL-pool_r is out of the hard bounds.
Error: Species concentration GDP_s is out of the hard bounds.
Mitochondrial Carrier (MC) TCDB:2.A.29.4.2
Warning: Species concentration UMP_c is out of the soft bounds.
Acetoacetate:CoA ligase (AMP-forming) Butanoate metabolism EC:6.2.1.16
Error: Species concentration Collagen_CO9A2_c is out of the hard bounds.
Warning: Species concentration GDP-4-dehydro-6-deoxy-D-mannose_c is out of the soft bounds.
Error: Species concentration NADH_m is out of the hard bounds.
Error: Species concentration Lathosterol_r is out of the hard bounds.
Error: Species concentration L-Xylulose_c is out of the hard bounds.
Warning: Species concentration Stearate_s is out of the soft bounds.
Error: Species concentration Oleate_r is out of the hard bounds.
Warning: Species concentration Collagen_COJA1_c is out of the soft bounds.
Warning: Species concentration gamma-Linolenate_r is out of the soft bounds.
Error: Species concentration Nicotinamide_s is out of the hard bounds.
Error: Species concentration linoleic-Carnitine_c is out of the hard bounds.
Error: Species concentration glycolithocholate_s is out of the hard bounds.
Error: Species concentration Nicotinate_s is out of the hard bounds.
Warning: Species concentration Serotonin_b is out of the soft bounds.
Error: Species concentration AKG_s is out of the hard bounds.
Nucleobase:Cation Symporter-2 (NCS2) TCDB:2.A.40.6.1
(S)-Malate:NADP+ oxidoreductase(oxaloacetate-decarboxylating) Pyruvate metabolism EC:1.1.1.38 EC:1.1.1.39
Warning: Species concentration ADP_c is out of the soft bounds.
Warning: Species concentration UDP_c is out of the soft bounds.
Error: Species concentration Chloride_s is out of the hard bounds.
Warning: Species concentration Heme_c is out of the soft bounds.
Error: Species concentration trans-4-Hydroxy-L-proline_m is out of the hard bounds.
Error: Species concentration GSH_m is out of the hard bounds.
2-Deoxy-D-ribose 1-phosphate 1,5-phosphomutase Pentose phosphate pathway EC:5.4.2.7
Warning: Species concentration mitoThioredoxin_m is out of the soft bounds.
(S)-2-methylbutanoyl-CoA:acceptor 2,3-oxidoreductase Valine, leucine and isoleucine degradation EC:1.3.99.12
Error: Species concentration Acetoacetyl-CoA_c is out of the hard bounds.
Warning: Species concentration Linoleate_r is out of the soft bounds.
Error: Species concentration lithocholate_c is out of the hard bounds.
Error: Species concentration NH3_c is out of the hard bounds.
Error: Species concentration ApoB100_l is out of the hard bounds.
Warning: Species concentration Cholate_b is out of the soft bounds.
4-imidazolone-5-propanoate amidohydrolase Histidine metabolism EC:3.5.2.7
Collagen alpha-1(XXIV) chain Protein assembly
Error: Species concentration leukotriene-e4_s is out of the hard bounds.
Error: Species concentration Arachidonyl-Carnitine_p is out of the hard bounds.
Error: Species concentration trans,cis-octadeca-2,9-dienoyl-CoA_m is out of the hard bounds.
Decanoyl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) Fatty acid biosynthesis EC:2.3.1.85
Error: Species concentration (2E)-Octadecenoyl-ACP_c is out of the hard bounds.
Error: Species concentration Trehalose_s is out of the hard bounds.
Error: Species concentration Histamine_s is out of the hard bounds.
Warning: Species concentration Glycogenin-G4G7_c is out of the soft bounds.
Error: Species concentration prostaglandin-e3_c is out of the hard bounds.
Error: Species concentration 4-Hydroxyphenylpyruvate_c is out of the hard bounds.
Error: Species concentration Palmitate_s is out of the hard bounds.
Warning: Species concentration Inositol_s is out of the soft bounds.
Error: Species concentration Acyl-CoA-VLDL-PI-pool_c is out of the hard bounds.
Error: Species concentration PPi_c is out of the hard bounds.
Error: Species concentration Collagen_CO3A1_c is out of the hard bounds.
Error: Species concentration Ceramide-1P-pool_c is out of the hard bounds.
Error: Species concentration Palmitoyl-CoA_r is out of the hard bounds.
D-Glucose-6-phosphate phosphohydrolase EC:3.1.3.9
Error: Species concentration LacCer-pool_r is out of the hard bounds.
Warning: Species concentration 4-Aminobutanal_s is out of the soft bounds.
Warning: Species concentration GTP_c is out of the soft bounds.
Warning: Species concentration dTTP_s is out of the soft bounds.
Warning: Species concentration Dihydrofolate_c is out of the soft bounds.
Error: Species concentration SAH_c is out of the hard bounds.
Error: Species concentration CDP-diacylglycerol-CL-pool_m is out of the hard bounds.
Warning: Species concentration Cholate_s is out of the soft bounds.
Warning: Species concentration Acetate_c is out of the soft bounds.
Error: Species concentration Collagen_LPP3_c is out of the hard bounds.
Warning: Species concentration ApoA1_r is out of the soft bounds.
Error: Species concentration 3-Methoxy-4-hydroxyphenylacetaldehyde_m is out of the hard bounds.
Error: Species concentration Methionine_s is out of the hard bounds.
Error: Species concentration Choloyl-CoA_c is out of the hard bounds.
Error: Species concentration N-Acetylglucosamine_l is out of the hard bounds.
inosine:orthophosphate ribosyltransferase Purine metabolism EC:2.4.2.1
Error: Species concentration dGMP_m is out of the hard bounds.
Error: Species concentration Arachidonyl-CoA_p is out of the hard bounds.
Propinol adenylate:CoA ligase (AMP-forming) Propanoate metabolism EC:6.2.1.17
Warning: Species concentration L-Octanoylcarnitine_m is out of the soft bounds.
Warning: Species concentration Valine_l is out of the soft bounds.
Error: Species concentration Anthranilate_c is out of the hard bounds.
Warning: Species concentration SAM_c is out of the soft bounds.
Error: Species concentration (2E)-Octenoyl-ACP_c is out of the hard bounds.
Warning: Species concentration Adenosine_s is out of the soft bounds.
Warning: Species concentration Collagen_FCN1_c is out of the soft bounds.
Error: Species concentration 4-Aminobutyrate_c is out of the hard bounds.
Warning: Species concentration (2E)-Octenoyl-CoA_m is out of the soft bounds.
Error: Species concentration Sphingosine-1P_c is out of the hard bounds.
Warning: Species concentration L-Palmitoylcarnitine_c is out of the soft bounds.
Error: Species concentration Ribulose-5P_c is out of the hard bounds.
Error: Species concentration Arachidonyl-Carnitine_c is out of the hard bounds.
dUTP nucleotidohydrolase Pyrimidine metabolism EC:3.6.1.23 EC:3.6.1.19
Error: Species concentration 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al_c is out of the hard bounds.
Error: Species concentration Linoleoyl-CoA_r is out of the hard bounds.
Error: Species concentration O2_s is out of the hard bounds.
Error: Species concentration Isoleucine_c is out of the hard bounds.
Warning: Species concentration CoA_m is out of the soft bounds.
Warning: Species concentration H2O_l is out of the soft bounds.
Error: Species concentration prostaglandin-f2alpha_s is out of the hard bounds.
myo-Inositol 1-phosphate phosphahydrolase Streptomycin biosynthesis / Inositol phosphate metabolism / Phosphatidylinositol signaling system EC:3.1.3.25
Error: Species concentration Pyridoxal_c is out of the hard bounds.
Warning: Species concentration NADH-redox-potential_m is out of the soft bounds.
Error: Species concentration Propinol_adenylate_m is out of the hard bounds.
Warning: Species concentration 3-Dehydrosphinganine_c is out of the soft bounds.
Error: Species concentration DHAP_c is out of the hard bounds.
Warning: Species concentration Acetyl-CoA_p is out of the soft bounds.
D-Fructose-1,6-bisphosphate 1-phosphohydrolase Carbon fixation EC:3.1.3.11
Error: Species concentration AMP_m is out of the hard bounds.
amylo-1,6-glucosidase, 4-alpha-glucanotransferase EC:2.4.1.25
Warning: Species concentration (2E)-Hexadecenoyl-CoA_r is out of the soft bounds.
Warning: Species concentration Pyridoxine-P_c is out of the soft bounds.
Error: Species concentration Arachidonate_c is out of the hard bounds.
Error: Species concentration Methionine_c is out of the hard bounds.
Warning: Species concentration HMG-CoA_c is out of the soft bounds.
3-Oxopropanoate:NAD+ oxidoreductase (decarboxylating, CoA-acetylating) Inositol metabolism / Alanine and aspartate metabolism / beta-Alanine metabolism / Propanoate metabolism EC:1.2.1.18
Error: Species concentration Pi_l is out of the hard bounds.
Error: Species concentration activated-sulphur_c is out of the hard bounds.
Warning: Species concentration PC-VLDL-pool_s is out of the soft bounds.
5'-Phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming) Purine metabolism EC:6.3.5.3
Error: Species concentration Erythrose-4P_c is out of the hard bounds.
Error: Species concentration PI-pool_r is out of the hard bounds.
5-methyltetrahydrofolate:NAD+ oxidoreductase One carbon pool by folate / Methane metabolism EC:1.5.1.20
Error: Species concentration Antichymotrypsin_l is out of the hard bounds.
Error: Species concentration Cytidine_s is out of the hard bounds.
Error: Species concentration Sarcosine_s is out of the hard bounds.
Error: Species concentration Pyruvate_m is out of the hard bounds.
Warning: Species concentration Dihydroneopterin_s is out of the soft bounds.
Error: Species concentration NADPH-redox-potential_m is out of the hard bounds.
Warning: Species concentration Ethanolamine-P_c is out of the soft bounds.
Error: Species concentration PG-CL-pool_m is out of the hard bounds.
Warning: Species concentration GSSG_s is out of the soft bounds.
Warning: Species concentration Cholesterol-ester-stea_l is out of the soft bounds.
Error: Species concentration (2E)-Hexenoyl-CoA_m is out of the hard bounds.
Galactosylglycerol galactohydrolase Galactose metabolism EC:3.2.1.22 EC:3.2.1.23
Error: Species concentration 3-Phosphonooxypyruvate_c is out of the hard bounds.
Warning: Species concentration Oxalate_m is out of the soft bounds.
Error: Species concentration (S)-3-Hydroxytetradecanoyl-CoA_m is out of the hard bounds.
Error: Species concentration Phosphocholine_c is out of the hard bounds.
Warning: Species concentration 2-Aminoadipate_6-semialdehyde_c is out of the soft bounds.
Error: Species concentration Collagen_CO4A1_c is out of the hard bounds.
Error: Species concentration gamma-Linolenoyl-CoA_c is out of the hard bounds.
Error: Species concentration gamma-Glutamyl-beta-cyanoalanine_s is out of the hard bounds.
Error: Species concentration thromboxane-b2_s is out of the hard bounds.
Warning: Species concentration GAP_c is out of the soft bounds.
Warning: Species concentration Dephospho-CoA_m is out of the soft bounds.
Error: Species concentration 3alpha,7alpha-Dihydroxy-5beta-cholestanate_c is out of the hard bounds.
Presqualene diphosphate:farnesyl-diphosphate farnesyltransferase Biosynthesis of steroids EC:2.5.1.21
Error: Species concentration Phosphatidate-VLDL-PE-pool_c is out of the hard bounds.
Error: Species concentration Linolenate_r is out of the hard bounds.
S-Formylglutathione hydrolase Methane metabolism EC:3.1.2.12
Error: Species concentration (S)-Hydroxydecanoyl-CoA_p is out of the hard bounds.
Error: Species concentration Hydroxymethylbilane_c is out of the hard bounds.
Error: Species concentration Isocitrate_m is out of the hard bounds.
Error: Species concentration Phenylacetaldehyde_m is out of the hard bounds.
Warning: Species concentration Deoxyinosine_c is out of the soft bounds.
Error: Species concentration Palmitate_r is out of the hard bounds.
Error: Species concentration 2-Methyl-3-oxopropanoate_m is out of the hard bounds.
Error: Species concentration Thiamin_s is out of the hard bounds.
Warning: Species concentration 2-Aminomuconate_c is out of the soft bounds.
5,6-Dihydrouracil amidohydrolase Pyrimidine metabolism / beta-Alanine metabolism / Pantothenate and CoA biosynthesis EC:3.5.2.2
Mitochondrial Carrier (MC) TCDB:2.A.29.2.4
Warning: Species concentration Gentisate_aldehyde_c is out of the soft bounds.
Error: Species concentration Homogentisate_c is out of the hard bounds.
Error: Species concentration Uracil_s is out of the hard bounds.
Warning: Species concentration Chloride_c is out of the soft bounds.
Error: Species concentration dGTP_m is out of the hard bounds.
Warning: Species concentration Methacrylyl-CoA_m is out of the soft bounds.
Warning: Species concentration S-Glutaryldihydrolipoamide_m is out of the soft bounds.
Error: Species concentration Spermidine_c is out of the hard bounds.
Warning: Species concentration 3-Oxotetradecanoyl-CoA_p is out of the soft bounds.
Warning: Species concentration Methylmalonate_c is out of the soft bounds.
Warning: Species concentration 1,2-Diacylglycerol-Bile-PC-pool_c is out of the soft bounds.
D-Fructose-2,6-bisphosphate 2-phosphohydrolase EC:3.1.3.46
UTP:alpha-D-glucose-1-phosphate uridylyltransferase Pentose and glucuronate interconversions / Nucleotide sugars metabolism EC:2.7.7.9
Warning: Species concentration Methionine_l is out of the soft bounds.
Error: Species concentration Taurocholate_b is out of the hard bounds.
Error: Species concentration Malonyl-Carnitin_r is out of the hard bounds.
Error: Species concentration Glycogenin_c is out of the hard bounds.
collagen, type XIII, alpha 1 Protein assembly
L-Glutamate:NADP+ oxidoreductase (deaminating) Glutamate metabolism EC:1.4.1.3 EC:1.4.1.4
Warning: Species concentration prostaglandin-f1alpha_c is out of the soft bounds.
Warning: Species concentration Hydracrylate_m is out of the soft bounds.
Warning: Species concentration dTMP_c is out of the soft bounds.
Error: Species concentration HDL_l is out of the hard bounds.
Warning: Species concentration Deamido-NAD_c is out of the soft bounds.
Error: Species concentration Proline_m is out of the hard bounds.
Warning: Species concentration Palmitate_p is out of the soft bounds.
Warning: Species concentration Acyl-CoA-VLDL-PE-pool_c is out of the soft bounds.
Protoporphyrinogen-IX:oxygen oxidoreductase Porphyrin and chlorophyll metabolism EC:1.3.3.4
Warning: Species concentration Isobutyryl-CoA_m is out of the soft bounds.
Error: Species concentration Stearoyl-CoA_r is out of the hard bounds.
Warning: Species concentration FADH-redox-potential_c is out of the soft bounds.
Error: Species concentration Collagen_CO1A2_c is out of the hard bounds.
Error: Species concentration 3-Hydroxyisobutyrate_m is out of the hard bounds.
Warning: Species concentration Collagen_CO6A1_c is out of the soft bounds.
Error: Species concentration Glucose-1P_s is out of the hard bounds.
Error: Species concentration Leucine_l is out of the hard bounds.
Error: Species concentration Glucosylceramide-pool_r is out of the hard bounds.
Error: Species concentration (R)-3-Hydroxydecanoyl-ACP_c is out of the hard bounds.
Warning: Species concentration FAD_s is out of the soft bounds.
Error: Species concentration cGMP_c is out of the hard bounds.
Warning: Species concentration 1-Acylglycerol-3P-CL-pool_m is out of the soft bounds.
Error: Species concentration 1,2-Diacylglycerol-VLDL-PC-pool_c is out of the hard bounds.
Warning: Species concentration Orotate_s is out of the soft bounds.
Error: Species concentration (S)-3-Hydroxyhexadecanoyl-CoA_m is out of the hard bounds.
Warning: Species concentration Serine_l is out of the soft bounds.
Error: Species concentration mitoThioredoxin_c is out of the hard bounds.
Error: Species concentration PE-PS-VLDL-pool_c is out of the hard bounds.
Collagen alpha-1(XI) chain Protein assembly
Warning: Species concentration 6-[(1S,2R)-1,2-Dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin_s is out of the soft bounds.
Error: Species concentration Acetoacetate_c is out of the hard bounds.
Error: Species concentration Collagen_SCRB1_c is out of the hard bounds.
Warning: Species concentration HMG-CoA_m is out of the soft bounds.
Error: Species concentration Guanosine_c is out of the hard bounds.
Warning: Species concentration Adenosylmethioninamine-potential_c is out of the soft bounds.
Error: Species concentration D-Tagatose-6P_c is out of the hard bounds.
Error: Species concentration prostaglandin-e1_s is out of the hard bounds.
Error: Species concentration HDL_r is out of the hard bounds.
Error: Species concentration Serotonin_s is out of the hard bounds.
Error: Species concentration Lipoamide_m is out of the hard bounds.
Error: Species concentration Butyrate_c is out of the hard bounds.
Warning: Species concentration Urea_s is out of the soft bounds.
collagen, type VI, alpha 2 Protein assembly
Error: Species concentration 2-Amino-3-carboxymuconate_semialdehyde_c is out of the hard bounds.
Warning: Species concentration Provitamin_D3_r is out of the soft bounds.
Warning: Species concentration (R)-3-Hydroxypalmitoyl-ACP_c is out of the soft bounds.
Error: Species concentration SM-pool_c is out of the hard bounds.
Warning: Species concentration Ribose_c is out of the soft bounds.
Error: Species concentration 1,2-Diacylglycerol-VLDL-PS-pool_c is out of the hard bounds.
Error: Species concentration dTTP_c is out of the hard bounds.
Error: Species concentration CDP-diacylglycerol-VLDL-PI-pool_c is out of the hard bounds.
Warning: Species concentration Acrylyl-CoA_m is out of the soft bounds.
Warning: Species concentration Pi_r is out of the soft bounds.
Dephospho-CoA nucleotidohydrolase Pantothenate and CoA biosynthesis EC:3.6.1.9
Error: Species concentration Collagen_FMOD_c is out of the hard bounds.
Error: Species concentration 1-Acylglycerol-VLDL-PC-pool_c is out of the hard bounds.
Error: Species concentration Hexanoyl-ACP_c is out of the hard bounds.
Warning: Species concentration dUDP_m is out of the soft bounds.
Error: Species concentration Valine_c is out of the hard bounds.
Error: Species concentration Dihomo-gamma-linolenate_c is out of the hard bounds.
Error: Species concentration HCO3-_s is out of the hard bounds.
Error: Species concentration Quinolinate_c is out of the hard bounds.
Warning: Species concentration PE-VLDL-pool_l is out of the soft bounds.
Warning: Species concentration Pyruvate_c is out of the soft bounds.
Warning: Species concentration GDP_c is out of the soft bounds.
Warning: Species concentration ApoC3_c is out of the soft bounds.
Error: Species concentration ACP_c is out of the hard bounds.
Mitochondrial Carrier (MC) TCDB:2.A.29.4.1
ATP phosphohydrolase (protein-secreting) Oxidative phosphorylation EC:3.6.-.-
3-Phosphoserine:2-oxoglutarate aminotransferase Glycine, serine and threonine metabolism EC:2.6.1.52
Warning: Species concentration Glycine_c is out of the soft bounds.
Warning: Species concentration 1-Acylglycerol-VLDL-PC-pool_c is out of the soft bounds.
Warning: Species concentration Bilirubin-monoglucuronoside_s is out of the soft bounds.
Error: Species concentration UDP_c is out of the hard bounds.
Error: Species concentration Acetylcholine_c is out of the hard bounds.
Error: Species concentration Heme_c is out of the hard bounds.
Warning: Species concentration Decanoyl-CoA_p is out of the soft bounds.
Error: Species concentration glycoursodeoxycholate_c is out of the hard bounds.
Error: Species concentration 4-Aminobutyrate_m is out of the hard bounds.
Warning: Species concentration Pantetheine_m is out of the soft bounds.
N-(omega)-Hydroxyarginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) Arginine and proline metabolism EC:1.14.13.39
Warning: Species concentration Serine_s is out of the soft bounds.
Warning: Species concentration Deoxyguanosine_m is out of the soft bounds.
L-Proline:NADP+ 5-oxidoreductase Arginine and proline metabolism EC:1.5.1.2
Warning: Species concentration dUMP_c is out of the soft bounds.
Error: Species concentration Cholesterol-ester-arach_r is out of the hard bounds.
Warning: Species concentration 1-Acylglycerol-3P-VLDL-PS-pool_c is out of the soft bounds.
Error: Species concentration Hydroxypyruvate_c is out of the hard bounds.
Warning: Species concentration 10-Formyl-THF_c is out of the soft bounds.
5,6-Dihydrothymine amidohydrolase Pyrimidine metabolism EC:3.5.2.2
Error: Species concentration prostaglandin-h2_c is out of the hard bounds.
Error: Species concentration Sulfite_c is out of the hard bounds.
Error: Species concentration FAICAR_c is out of the hard bounds.
Warning: Species concentration Aspartate_m is out of the soft bounds.