MODEL1112150000
type: SBMLModel
reaction: COPASI15
name: Tiemann2011_PhenotypeTransitions
compartment: COPASI2
reaction: COPASI26
reaction: COPASI18
reaction: COPASI22
function def: 063128
volume units: MODEL1105180000#
species: COPASI10
reaction: COPASI30
name: Constant flux (irreversible)
reaction: COPASI17
area units: 802883
units def: 063164
species: COPASI9
species: COPASI7
length unit: 802859
reaction: COPASI13
reaction: COPASI14
units def: 063140
reaction: COPASI28
reaction: COPASI29
species: COPASI12
is described by: http://identifiers.org/pubmed/22029623
reaction: COPASI33
time units: 063140
reaction: COPASI25
substance units: 063164
reaction: COPASI21
species: COPASI5
reaction: COPASI24
reaction: COPASI16
reaction: COPASI20
curated: false
species: COPASI8
species: COPASI11
notes: To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
reaction: COPASI27
reaction: COPASI35
compartment: COPASI3
reaction: COPASI34
reaction: COPASI31
reaction: COPASI32
species: COPASI6
reaction: COPASI23
reaction: COPASI19
species: COPASI4

COPASI15
type: Reaction
kinetic law: 063284
product: 063272
reactant: 063260
fast: false
reversible: false
name: CEforcyt

063296
type: LocalParameter
value: 5.3418
name: k1

063272
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

COPASI5
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.6624
initial amount: NaN
in compartment: COPASI2
name: CE_cyt

COPASI2
type: Compartment
constant: true
size: 0.0025
spatial dimensions: 3.0
name: Liver

063260
type: SpeciesReference
stoichiometry: 1.0
species: COPASI4

COPASI4
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.9366
initial amount: NaN
in compartment: COPASI2
name: FC

COPASI26
type: Reaction
kinetic law: 063764
product: 063752
reactant: 063740
fast: false
reversible: false
name: VLDLTG

063776
type: LocalParameter
value: 0.019342
name: k1

063752
type: SpeciesReference
stoichiometry: 1.0
species: COPASI9

COPASI9
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.46
initial amount: NaN
in compartment: COPASI3
name: TG_plasma

COPASI3
type: Compartment
constant: true
size: 0.0025
spatial dimensions: 3.0
name: Plasma

063740
type: SpeciesReference
stoichiometry: 1.0
species: COPASI8

COPASI8
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: TG_ER

COPASI18
type: Reaction
kinetic law: 063428
product: 063416
reactant: 063404
fast: false
reversible: false
name: CEdefer

063440
type: LocalParameter
value: 0.610892
name: k1

063416
type: SpeciesReference
stoichiometry: 1.0
species: COPASI4

063404
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

COPASI6
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: CE_ER

COPASI22
type: Reaction
kinetic law: 063584
product: 063572
fast: false
reversible: false
name: TGproder

063596
type: LocalParameter
value: 1.30725E-5
name: v

063572
type: SpeciesReference
stoichiometry: 1.0
species: COPASI8

COPASI10
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.61
initial amount: NaN
in compartment: COPASI3
name: CE_plasma

COPASI30
type: Reaction
kinetic law: 063944
reactant: 063932
fast: false
reversible: false
name: TGuptper

063956
type: LocalParameter
value: 0.0057377
name: k1

063932
type: SpeciesReference
stoichiometry: 1.0
species: COPASI9

COPASI17
type: Reaction
kinetic law: 063380
product: 063368
reactant: 063356
fast: false
reversible: false
name: CEforer

063392
type: LocalParameter
value: 0.252437
name: k1

063368
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

063356
type: SpeciesReference
stoichiometry: 1.0
species: COPASI4

063176
type: SBMLUnit
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE

COPASI7
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 3.1832
initial amount: NaN
in compartment: COPASI2
name: TG_cyt

COPASI13
type: Reaction
kinetic law: 063200
product: 063188
fast: false
reversible: false
name: FCprod

063212
type: LocalParameter
value: 0.0245
name: v

063188
type: SpeciesReference
stoichiometry: 1.0
species: COPASI4

COPASI14
type: Reaction
kinetic law: 063236
reactant: 063224
fast: false
reversible: false
name: FCmet

063248
type: LocalParameter
value: 0.0488485
name: k1

063224
type: SpeciesReference
stoichiometry: 1.0
species: COPASI4

063152
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 3600.0
kind: SECOND

COPASI28
type: Reaction
kinetic law: 063860
product: 063848
reactant: 063836
fast: false
reversible: false
name: TGupthep

063872
type: LocalParameter
value: 0.00132591
name: k1

063848
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

063836
type: SpeciesReference
stoichiometry: 1.0
species: COPASI9

COPASI29
type: Reaction
kinetic law: 063908
product: 063896
reactant: 063884
fast: false
reversible: false
name: CEupthep

063920
type: LocalParameter
value: 0.00132591
name: k1

063896
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

063884
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

COPASI12
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.34
initial amount: NaN
in compartment: COPASI3
name: FFA

COPASI33
type: Reaction
kinetic law: 064064
product: 064052
reactant: 064040
fast: false
reversible: false
name: CEupthdl

064076
type: LocalParameter
value: 1.36296E-4
name: k1

064052
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

064040
type: SpeciesReference
stoichiometry: 1.0
species: COPASI11

COPASI11
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.35
initial amount: NaN
in compartment: COPASI3
name: CE_HDL

COPASI25
type: Reaction
kinetic law: 063716
product: 063704
reactant: 063692
fast: false
reversible: false
name: fFFA

063728
type: LocalParameter
value: 0.0155327
name: k1

063704
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

063692
type: SpeciesReference
stoichiometry: 1.0
species: COPASI12

COPASI21
type: Reaction
kinetic law: 063548
product: 063536
reactant: 063524
fast: false
reversible: false
name: TGforcyt

063560
type: LocalParameter
value: 5.60892
name: k1

063536
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

063524
type: SpeciesReference
stoichiometry: 1.0
species: COPASI8

COPASI24
type: Reaction
kinetic law: 063668
product: 063656
reactant: 063644
fast: false
reversible: false
name: TGforer

063680
type: LocalParameter
value: 3.05246
name: k1

063656
type: SpeciesReference
stoichiometry: 1.0
species: COPASI8

063644
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

COPASI16
type: Reaction
kinetic law: 063332
product: 063320
reactant: 063308
fast: false
reversible: false
name: CEdefcyt

063344
type: LocalParameter
value: 27.0264
name: k1

063320
type: SpeciesReference
stoichiometry: 1.0
species: COPASI4

063308
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

COPASI20
type: Reaction
kinetic law: 063500
reactant: 063488
fast: false
reversible: false
name: TGmetcyt

063512
type: LocalParameter
value: 0.701735
name: k1

063488
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

COPASI27
type: Reaction
kinetic law: 063812
product: 063800
reactant: 063788
fast: false
reversible: false
name: VLDLCE

063824
type: LocalParameter
value: 0.00308588
name: k1

063800
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

063788
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

COPASI35
type: Reaction
kinetic law: 064148
reactant: 064136
fast: false
reversible: false
name: TGhydper

064160
type: LocalParameter
value: 0.185873
name: k1

064136
type: SpeciesReference
stoichiometry: 1.0
species: COPASI9

COPASI34
type: Reaction
kinetic law: 064112
product: 064100
reactant: 064088
fast: false
reversible: false
name: TGhydhep

064124
type: LocalParameter
value: 0.0226027
name: k1

064100
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

064088
type: SpeciesReference
stoichiometry: 1.0
species: COPASI9

COPASI31
type: Reaction
kinetic law: 063980
reactant: 063968
fast: false
reversible: false
name: CEuptper

063992
type: LocalParameter
value: 0.0057377
name: k1

063968
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

COPASI32
type: Reaction
kinetic law: 064016
product: 064004
fast: false
reversible: false
name: CEforhdl

064028
type: LocalParameter
value: 0.0736
name: v

064004
type: SpeciesReference
stoichiometry: 1.0
species: COPASI11

COPASI23
type: Reaction
kinetic law: 063620
reactant: 063608
fast: false
reversible: false
name: TGmeter

063632
type: LocalParameter
value: 0.340947
name: k1

063608
type: SpeciesReference
stoichiometry: 1.0
species: COPASI8

COPASI19
type: Reaction
kinetic law: 063464
product: 063452
fast: false
reversible: false
name: TGprodcyt

063476
type: LocalParameter
value: 1.80635E-5
name: v

063452
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7