methylmalonyl-CoA epimerase, mitochondrial
Nicotinamide adenine dinucleotide phosphate - reduced
Nicotinamide adenine dinucleotide phosphate
methylenetetrahydrofolate dehydrogenase (NADP), mitochondrial
2-oxoadipate transaminase, mitochondrial
3-(4-hydroxyphenyl)pyruvate mitochondrial transport via proton symport
"hexadecenoyl carnitine (C16:1Crn, n-7)"
hexadecenoyl carnitine transprot (C16:1Crn, n7)
hydroxysteroid (17-beta) dehydrogenase 4
Nicotinamide adenine dinucleotide - reduced
sodium transport in/out via proton antiport (one H+), blood
"eicosadienoyl carnitine (C20:2Crn, n-6)"
carnitine eicosadienoyltransferase (C20:2Crn, n6), mitochondrial
fatty-acid--CoA ligase (eicosadienoate, C20:2 n-9)
Propionyl-CoA carboxylase, mitochondrial
glycerol 3-phosphate acyltransferase, adipocyte specific
"1-Acyl-sn-glycerol 3-phosphate, adipocyte"
C-3 sterol dehydrogenase NADPH, (4-methylzymosterol)
fatty-acid--CoA ligase (eicosatetraenoate, C20:4 n-6)
"phosphatidylethanolamine, human adipoctye"
Phosphoenolpyruvate carboxykinase (GTP), mitochondrial
bicarbonate transport (Na/HCO3 cotransport), blood
phosphatidate reversible transport, mitochondrial, myocyte
"eicosapentaenoyl carnitine (C20:5Crn, n-3)"
"ocosatetraenoyl carnitine (C22:4Crn, n-6)"
ocosatetraenoyl carnitine transport (C22:4Crn, n6)
lathosterol oxidase (NADP), endoplasmic reticulum
"eicosatrienoyl carnitine (C20:3Crn, n-6)"
carnitine octadecenoyltransferase (C18:1Crn, n9)
4-aminobutyrate transaminase, reversible (mitochondrial)
glyceraldehyde-3-phosphate dehydrogenase (NAD)
3-Methyl-2-oxobutanoate dehydrogenase, mitochondrial
dihydroorotate dehydrogenase (mitochondrial)
Urea transport via facilitate diffusion, blood
malate oxaloacetate shuttle, mitochondrial
fatty-acyl-CoA elongation (C20:4CoA, n3)
"stearidonyl coenzyme A (C18:4CoA, n-3)"
6-Phospho-D-gluconate transport in/out via proton symport
cardiolipin synthase, mitochondrial, myocyte
acetyl-CoA C-acetyltransferase, mitochondrial
dodecanoate (C12:0) mammalian cell transport
4-aminobutanoate mitochondrial transport via diffusion
"octadecadienoyl carnitine (C18:2Crn, n-6)"
octadecadienoyl carnitine transferase (C18:2Crn, n6)
"eicosatetraenoyl carnitine (C20:4Crn, n-6)"
carnitine eicosatetraenoyltransferase (C20:4Crn, n6), mitochondrial
1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
fatty-acid--CoA ligase (ocosatetraenoate, C22:4 n-6)
Glutamine transport, proton coupled, mitochondria
3-hydroxyacyl-CoA dehydratase (3-hydroxybutanoyl-CoA)
3',5'-cyclic-nucleotide phosphodiesterase
fatty acid transport via diffusion, extrasystem
acyl-Coenzyme A oxidase 2, branched chain
Phospholipase A (phosphatidylcholine), hepatocyte
aminomuconate-semialdehyde dehydrogenase
L-histidine transport in via sodium symport, blood
glutaryl-CoA dehydrogenase, mitochondrial
"Phosphatidylglycerol, human hepatocyte"
cholesterol efflux (ATP depedent), blood
octadecenoyl carnitine transport (C18:1Crn, n5)
fatty-acid--CoA ligase (eicosenoate, C20:1 n-11)
Ceramide cholinephosphotransferase, human myocyte
"phosphatidyl-1D-myo-inositol, human hepatocyte"
phosphatidylinositol synthase, human hepatocyte
cytochrome P450 lanosterol 14-alpha-demethylase
"octadecatrienoyl carnitine (C18:3Crn, n3)"
carnitine octadecanoyltransferase (C18:0Crn)
fatty acyl-CoA desaturase (C22:5CoA, n3 -> C22:6CoA, n3)
fatty-acid--CoA ligase (octadecenoate, C18:1 n-9)
ribonucleoside-diphosphate reductase (UDP)
"2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate"
methylenetetrahydrofolate reductase (NADPH2)
3-hydroxyacyl-CoA dehydrogenase (2-Methylacetoacetyl-CoA), mitochondrial
glucose 6-phosphate dehydrogenase, endoplasmic reticulum
CDP-diacylglycerol--serine O-phosphatidyltransferae, mitochondrial, human hepatocyte
"Phosphatidylglycerophosphate, Hybridoma"
glucose transport, endoplasmic reticulum
Ornithine/citrulline antiport, mitocondiral
L-Glutamate 5-semialdehyde transport, mitochondrial
Palmitoylcarnitine shuttle (C16:0Crn), mitochondrial
alcohol dehydrogenase (ethanol, NADP), forward reaction
"1-Acyl-sn-glycerol 3-phosphate, human myocyte"
1-Acyl-glycerol-3-phosphate acyltransferase, myocyte specific
octadecatrienoyl carnitine transferase (C18:3Crn, n3)
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
carbamoyl-phosphate synthase (glutamine-hydrolysing)
carnitine eicosatrienoyltransferase (C20:3Crn, n6)
phosphoribosylaminoimidazole carboxylase
formimidoyltetrahydrofolate cyclodeaminase
carnitine octadecenoyltransferase (C18:1Crn, n7)
"docosapentaenoyl carnitine (C22:5Crn, n-3)"
docosapentaenoyl carnitine transport (C22:5Crn, n3)
L-methionine transport in via sodium symport, blood
"phosphatidyl-1D-myo-inositol, human myocyte"
"phosphatidylethanolamine, human myocyte"
Biomass Demand, Human Myocyte (biosynthetic GAM)
methylenetetrahydrofolate dehydrogenase (NADP)
aldehyde dehydrogenase (NAD), mitochondrial
glutamate-5-semialdehyde dehydrogenase, mitochondrial
phosphomevalonate kinase, reversible, peroxisome
L-phenylalanine transport via diffusion (extracellular to cytosol)
tetradecanoyl carnitine transport (C14:0Crn)
phosphopantothenoylcysteine decarboxylase
carnitine eicosenoyltransferase (C20:1Crn, n9)
Palmitoyl-CoA desaturase (n-C17:0CoA -> C17:1CoA, n-8)
nucleoside-diphosphate kinase (ATP:dADP)
L-glutamate reversible transport via proton symport, mitochondrial
stearoyl-CoA desaturase (n-C20:0CoA -> C20:1CoA, n-11)
glucose 6-phosphate endoplasmic reticular transport via diffusion
fatty-acid--CoA ligase (docosenoate, C22:1 n-9)
carnitine pentadecanoyltransferase (C15:0Crn), mitochondria
L-asparagine transport in via sodium symport, blood
CDP-Diacylglycerol synthetase, updated human myocyte
glycine passive transport to mitochondria
alcohol dehydrogenase, forward rxn (ethanol -> acetaldehyde)
"docosapentaenoyl carnitine (C22:5Crn, n-6)"
aspartate carbamoyltransferase (reversible)
glucose transport (uniport: facilitated diffusion)
Octadecatrienoate (C18:3, n-6) transport
carnitine-propcarnitine carrier, peroxisomal
HCO3 equilibration reaction, mitochondrial
aldehyde dehydrogenase (acetaldehyde, NAD)
C-3 sterol dehydrogenase NADH, (4-methylzymosterol)
L-isoleucine transport via diffusion, blood
1-Acyl-glycerol-3-phosphate acyltransferase, adipocyte specific
Aminoacetone:oxygen oxidoreductase(deaminating)(flavin-containing)
fatty acid transport via diffusion, blood
"docosahexaenoyl carnitine (C22:6Crn, n-3)"
fatty-acid--CoA ligase (eicosenoate, C20:1 n-9)
3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA) mitochondrial
carnitine docosahexaenoyltransferase (C22:6Crn, n3), mitochondrial
Cholesterol transport, endoplasmic reticulum
This model is from the article: A multi-tissue type genome-scale metabolic network for analysis of whole-body systems physiology. Bordbar A, Feist AM, Usaite-Black R, Woodcock J, Palsson BO, Famili I. BMC Syst Biol. 2011 Oct 31;5(1):180. 22041191 , Abstract: ABSTRACT: BACKGROUND: Genome-scale metabolic reconstructions provide a biologically meaningful mechanistic basis for the genotype-phenotype relationship. The global human metabolic network, termed Recon 1, has recently been reconstructed allowing the systems analysis of human metabolic physiology and pathology. Utilizing high-throughput data, Recon 1 has recently been tailored to different cells and tissues, including the liver, kidney, brain, and alveolar macrophage. These models have shown utility in the study of systems medicine. However, no integrated analysis between human tissues has been done. RESULTS: To describe tissue-specific functions, Recon 1 was tailored to describe metabolism in three human cells: adipocytes, hepatocytes, and myocytes. These cell-specific networks were manually curated and validated based on known cellular metabolic functions. To study intercellular interactions, a novel multi-tissue type modeling approach was developed to integrate the metabolic functions for the three cell types, and subsequently used to simulate known integrated metabolic cycles. In addition, the multi-tissue model was used to study diabetes: a pathology with systemic properties. High-throughput data was integrated with the network to determine differential metabolic activity between obese and type II obese gastric bypass patients in a whole-body context. CONCLUSION: The multi-tissue type modeling approach presented provides a platform to study integrated metabolic states. As more cell and tissue-specific models are released, it is critical to develop a framework in which to study their interdependencies. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
glycerol-3-phosphate transport, mitochondrial
fatty-acid--CoA ligase (docosanoate, C22:0)
fatty-acid--CoA ligase (eicosatrienoate, C20:3 n-6), hepatocyte
"Phosphatidylethanolamine, human hepatocyte"
"Averaged fatty acyl CoA, human myocyte"
acyl-coA cholesterol acyltransferase, myocyte
"Phosphatidylglycerophosphate, human adipocyte"
phosphatidylglycerol phosphate phosphatase A, mitochondrial, human adipocyte
glutamate dehydrogenase (NAD), mitochondrial
fatty-acid--CoA ligase (eicosanoate, C20:0)
fatty-acid--CoA ligase (octadecadienoate, C18:3 n-3), hepatocyte
"octadecatrienoyl carnitine (C18:3Crn, n6)"
carnitine octadecatrienoyltransferase (C18:3Crn, n6)
Hydroxymethylglutaryl-CoA reversible mitochondrial transport
carnitine ocosatetraenoyltransferase (C22:4Crn, n6)
D-Fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase
bile acid Coenzyme A: amino acid N-acyltransferase
"average fatty-acyl CoA, human hepatocyte"
"eicosatrienoyl carnitine (C20:3Crn, n9)"
carnitine octadecanoyltransferase (C18:0Crn), mitochondria
phosphate transporter, endoplasmic reticulum
eicosatetraenoyl carnitine transport (C20:5Crn, n3)
UDPglucose--hexose-1-phosphate uridylyltransferase
fatty-acyl-CoA elongation (n-C20:3CoA, n6)
methylenetetrahydrofolate dehydrogenase (NAD), mitochondrial
L-glutamate 5-semialdehyde dehydratase (spontaneous)
Nucleoside triphosphate pyrophosphorylase (atp)
dodecanoyl carnitine transport (C12:0Crn)
cysteinesulfinate-aspartate mitochondrial shuttle
Octadecatrienoate (C18:3, n-3) transport
pentadecanoyl carnitine transport (C15:0Crn)
saccharopine dehydrogenase (NADP, L-lysine-forming), mitochondrial
glycine C-acetyltransferase, mitochondrial
carnitine O-palmitoyltransferase (C16:0Crn)
cholesterol ester transport, blood, hepatocyte
phosphate transport in/out via proton symporter
glycerol-3-phosphate dehydrogenase (NAD)
carnitine octadecatrienoyltransferase (C18:3Crn, n6), mitochondrial
carnitine octadecadienoyltransferase (C18:2Crn, n6)
eicosanoate transport (n-C20:0), cytosol to blood
CO2 transport out via diffusion, exchange w blood
Octadecanoate (n-C18:0) transport in via uniport
carnitine docosapentaenoyltransferase (C22:5Crn, n3), mitochondrial
5,6,7,8-Tetrahydrofolate transport, diffusion, mitochondrial
isopentenyl diphosphate transport, peroxisome
nucleoside-diphosphate kinase (ATP:CDP), mitochondrial
CO2 transport (diffusion), mitochondrial
fatty-acid--CoA ligase (heptadecanoate, C15:0)
Tetradecanoate (n-C14:0) transport in via uniport
L-glutamine reversible transport via sodium symport, blood
C-14 sterol reductase, endoplasmic reticulum
fatty-acid--CoA ligase (heptadecanoate, C17:0)
eicosatetraenoyl carnitine transport (C20:4Crn, n6)
"average fatty-acyl CoA, human adipocyte"
ubiquinol-6 cytochrome c reductase, Complex III
phosphoribosylglycinamide formyltransferase, irreversible
lathosterol oxidase (NAD), endoplasmic reticulum
L-carnitine inward transport by Na+ symport
ribonucleoside-diphosphate reductase (ADP)
2-Oxoglutarate dehydrogenase complex, mitochondrial
carnitine docosahexaenoyltransferase (C22:6Crn, n3)
D-lactate transport via proton symport, blood
fatty-acid--CoA ligase (octadecadienoate, C18:2 n-6)
fatty acyl-CoA desaturase (C20:4CoA, n3 -> C20:5CoA, n3)
glycine reversible transport via sodium symport, blood
acetate mitochondrial transport via proton symport
glutamate aspartate carrier, cytosolic/mitochondrial
carnitine pentadecanoyltransferase (C15:0Crn)
3-hydroxybutyrate transport in/out via proton symport, blood
"phosphatidyl-1D-myo-inositol, human adipocyte"
"tetradecenoyl carnitine (C14:1Crn, n-7)"
carnitine tetradecenoyltransferase (C14:1Crn, n7)
eicosadienoyl-CoA desaturase (C20:2CoA,n-9 -> C20:3CoA,n-9)
Docosapentaenoate (C22:5, n-6) transport
cytochrome c oxidase (mitochondrial 4 protons/4 cyto)
phosphatidylinositol synthase, human myocyte
S-(hydroxymethyl)glutathione dehydrogenase
nucleoside-diphosphate kinase (ATP:dTDP)
carnitine pentadecanoyltransferase (C17:0Crn)
carnitine ocosatetraenoyltransferase (C22:4Crn, n6), mitochondrial
ribonucleoside-diphosphate reductase (GDP)
aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
carnitine dodecanoyltransferase (C12:0Crn), mitochondria
6-phosphogluconolactonase, endoplasmic reticulum
stearoyl-CoA desaturase (C18:3CoA, n3 -> C18:4CoA, n3)
eicosatrienoyl carnitine transport (C20:3Crn, n6)
Eicosapentaenoate (C20:5, n-3) transport
glutamine phosphoribosyldiphosphate amidotransferase
3-hydroxyisobutyrate dehydrogenase, mitochondrial
carnitine O-aceyltransferase, mitochondrial
carnitine eicosadienoyltransferase (C20:2Crn, n6)
fatty-acid--CoA ligase (eicosapentaenoate, C20:5 n-3)
"Phosphatidylglycerophosphate, human myocyte"
phosphatidylglycerol phosphate phosphatase A, mitochondrial, human myocyte
dimethylallyl diphosphate transport, peroxisome
2-oxoadipate shuttle (cytosol/mitochondria)
Squalene synthase, endoplasmic reticulum
fatty-acyl-CoA elongation (C22:5CoA, n3)
5,10-Methylenetetrahydrofolate transport, diffusion, mitochondrial
phosphatidylserine decarboxylase, human hepatocyte
phosphoribosylaminoimidazolecarboxamide formyltransferase
Lysine mitochondrial transport via ornithine carrier
fatty-acid--CoA ligase (hexadecenoate, C16:1 n-7)
alphaketobutyrate dehydrogenase (mitochondrial)
octadecanoyl carnitine transport (C18:0Crn)
"tetradecenoyl carnitine (C14:1Crn, n-5)"
isopentenyl-diphosphate D-isomerase, peroxisomal
glycerol transport in/out via diffusion reversible
docosahexaenoyl carnitine transport (C22:6Crn, n3)
Leucine transport, Homo Sapiens mitochondria
eicosatrienoyl carnitine transport (C20:3Crn, n9)
L-glutamate 5-semialdehyde dehydratase (spontaneous) mitochondrial
Phosphatidylserine synthase 1, human adipocyte
methenyltetrahydrofolate cyclohydrolase, mitochondrial
L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing)
acetoacetate transport via proton symport, blood
carbonate dehydratase (HCO3 equilibration reaction), blood
carnitine eicosenoyltransferase (C20:1Crn, n11), mitochondrial
fatty-acid--CoA ligase (octadecenoate, C18:1 n-5)
carnitine hexadecenoyltransferase (C16:1Crn, n7)
2-oxoglutarate dehydrogenase, mitochondrial
fatty-acid--CoA ligase (docosahexaenoate, C22:6 n-3)
diacylglycerol cholinephosphotransferase, human hepatocyte
eicosenoyl carnitine transport (C20:1Crn, n9)
L-alanine/glycine reversible exchange, blood
C-4 sterol methyl oxidase (4,4-dimethylzymosterol), endoplasmic reticulum
fatty-acid--CoA ligase (eicosatetraenoate, C20:4 n-3)
fatty acid synthase (n-C8:0), lumped reaction
L-leucine transport via diffusion, blood
Myristoyl-CoA desaturase (n-C14:0CoA -> C14:1CoA, n-7)
carnitine octadecatrienoyltransferase (C18:3Crn, n3)
phosphatidylserine decarboxylase, human myocyte
phosphoribosylaminoimidazolesuccinocarboxamide synthase
L-lactate reversible transport via proton symport
Palmitoyl-CoA desaturase (n-C16:0CoA -> C16:1CoA, n-7)
aminocarboxymuconate-semialdehyde decarboxylase
lanosterol synthase, endoplasmic reticulum
fatty acyl-CoA desaturase (C20:3CoA, n6 -> C20:4CoA, n6)
octadecenoyl carnitine transport (C18:1Crn, n9)
carnitine pentadecanoyltransferase (C17:0CoA), mitochondrial
saccharopine dehydrogenase (NAD, L-glutamate-forming), mitochondrial
C-3 sterol keto reductase (zymosterol), endoplasmic reticulum
carnitine octadecenoyltransferase (C18:1Crn, n9), mitochondrial
alphaketobutyrate transport (mitochondrial)
carnitine octadecatrienoyltransferase (C18:3Crn, n3), mitochondrial
L-Serine/Glutamine reversible exchange, blood
carnitine octadecenoyltransferase (C18:1Crn, n5)
formate-tetrahydrofolate ligase, mitochondrial
ribonucleoside-diphosphate reductase (CDP)
fatty-acyl-CoA elongation (C22:4CoA, n6)
inorganic diphosphatase, endoplasmic reticulum
carnitine tetradecenoyltransferase (C14:1Crn, n7), mitochondrial
carnitine eicosanoyltransferase (C20:0Crn), mitochondria
carnitine docosapentaenoyltransferase (C22:5Crn, n3)
Eicosatetraenoate (C20:4, n-6) transport
hydroxymethylglutaryl-CoA lyase, mitochondrial
fatty-acid--CoA ligase (heptadecenoate, C17:1 n-8)
diacylglycerol pyrophosphate phosphatase, human hepatocyte
Myristicoyl-CoA desaturase (n-C14:0CoA -> C14:1CoA, n-5)
succinate-semialdehyde dehydrogenase, mitochondrial
carnitine palmitoyltransferase (C16:0Crn), mitochondrial
Palmitoyl-CoA desaturase (n-C16:0CoA -> C16:1CoA, n-9)
octadecenoyl carnitine transferase (C18:1Crn, n7)
Biomass Demand, Human Adipocyte (biosynthetic GAM)
cardiolipin synthase, mitochondrial adipocyte
S-adenosyl-L-methionine methyltransferase
carnitine O-aceyltransferase, peroxisomal
tyrosine mitochondrial transport via proton symport
carnitine eicosatetraenoyltransferase (C20:5Crn, n3)
carnitine hexadecenoyltransferase (C16:1Crn, n7), mitochondrial
5-Amino-4-oxopentanoate mitochondrial transport
lipid, flip-flop intracellular transport
carnitine dodecanoyltransferase (C12:0Crn)
Valine transport, Homo Sapiens passive diffusion
fructose transport (uniport: facilitated diffusion)
Phosphatidylserine synthase 1, human myocyte
carnitine eicosatetraenoyltransferase (C20:5Crn, n3), mitochondrial
glutamate dehydrogenase (NADP), mitochondrial
UTP-glucose-1-phosphate uridylyltransferase
CDP-diacylglycerol--serine O-phosphatidyltransferase, mitochondrial, human myocyte
carnitine octadecadienoyltransferase (C18:2Crn, n6), mitochondrial
diacylglycerol cholinephosphotransferase, human adipocyte
stearoyl-CoA desaturase (n-C18:0CoA -> C18:1CoA, n-9), adipocyte
phosphatidate reversible transport, mitochondrial, adipocyte
triacylglycerol hydrolase, human myocyte
phosphate peroxisomal transport via proton symport
CDP-Diacylglycerol synthetase, human adipocyte
fatty-acid--CoA ligase (eicosatrienoate, C20:3 n-9)
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
phosphoribosylformylglycinamidine synthase
fatty-acid--CoA ligase (docosapentaenoate, C22:5 n-3)
ribulose 5-phosphate 3-epimerase, endoplasmic reticulum
"hexadecenoyl carnitine (C16:1Crn, n-9)"
carnitine hexadecenoyltransferase (C16:1Crn, n9)
nucleoside-diphosphate kinase (ATP:dGDP)
5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase
fatty-acid--CoA ligase (isolinoleate, C18:2 n-9)
ornithine carbamoyltransferase, mitochondrial
carnitine octadecenoyltransferase (C18:1Crn, n5), mitochondrial
L-cysteine reversible transport via sodium symport, reversible, blood
carnitine eicosenoyltransferase (C20:1Crn, n9), mitochondrial
L-threonine/glycine reversible exchange, blood
stearoyl-CoA desaturase (n-C22:0CoA -> C22:1CoA, n-9)
3-Hydroxy-2-methylpropanoate, proton symporter
diacylglycerol pyrophosphate phosphatase, human myocyte
carnitine eicosatrienoyltransferase (C20:3Crn, n6), mitochondrial
L-2-amino-3-oxobutanoate decarboxylation, mitochondrial
eicosadienoyl carnitine transport (C20:2Crn, n6)
cardiolipin reversible transport, mitochondria, adipocyte
docosenoyl carnitine transport (C22:1Crn, n9)
carnitine docosapentaenoyltransferase (C22:5Crn, n6), mitochondrial
carnitine tetradecanoyltransferase (C14:0Crn, mitochondria
cytochrome P450, family 7, subfamily A, polypeptide 1
Phosphatidylserine synthase 1, human hepatocyte
asparagine synthase (glutamine-hydrolysing)
monoacylglycerol hydrolase, human adipocyte
carnitine tetradecanoyltransferase (C14:0Crn)
CDP-Diacylglycerol synthetase, mitochondrial, human adipocyte
Ceramide cholinephosphotransferase, hepatocyte
carnitine eicosatrienoyltransferase (C20:3Crn, n9), mitochondrial
nucleoside-diphosphate kinase (ATP:dCDP)
carnitine tetradecenoyltransferase (C14:1Crn, n5)
acetoacetate transport via proton symport, mitochondrial
carnitine docosapentaenoyltransferase (C22:5Crn, n6)
glycerol 3-phosphate acyltransferase, myocyte specific
creatine phosphate dephosphorylation, spontaneous
ornithine transport via diffusion, blood
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
acyl-CoA dehydrogenase (butanoyl-CoA C4:0CoA)
eicosanoyl carnitine transport (C20:0Crn)
stearoyl-CoA desaturase (n-C18:0CoA -> C18:1CoA, n-7)
cardiolipin reversible transport, mitochondria, myocyte
acetate transport in/out via proton symport
carnitine octadecenoyltransferase (C18:1Crn, n7), mitochondrial
triacylglycerol hydrolase, human hepatocyte
phosphatidylinositol synthase, human adipocyte
uroporphyrinogen decarboxylase (uroporphyrinogen III)
methylcrotonoyl-CoA carboxylase, mitochondrial
myosin-ADP-Pi attachment, myocyte cytosol
Ceramide cholinephosphotransferase, adipocyte
CDP-diacylglycerol--serine O-phosphatidyltransferae, mitochondrial, human adipoctye
Creatine Na+ symporter, blood to cytosol
pyruvate reversible transport via proton symport, blood
(R)-3-Hydroxybutanoate:NAD+ oxidoreductase
fatty-acid--CoA ligase (tetradecenoate, C14:1 n-5)
phosphogluconate dehydrogenase, endoplasmic reticulum
Eicosatetraenoate (C20:4, n-3) transport
carnitine eicosatetraenoyltransferase (C20:4Crn, n6)
fatty acyl-CoA desaturase (C22:4CoA, n6 -> C22:5CoA, n6)
Creatine transport to/from mitochondria via diffusion
phosphatidylserine decarboxylase, human adipocyte
Squalene epoxidase, endoplasmic reticular
Oleoyl-CoA desaturase (C18:2CoA, n6 -> C18:3CoA, n6)
(S)-Methylmalonate semialdehyde transport, mitochondrial
phosphatidylglycerol phosphate phosphatase A, mitochondrial, human hepatocyte
linoleoyl-CoA desaturase (C18:1CoA,n-9 -> C18:2CoA,n-9)
diacylglycerol cholinephosphotransferase, human myocyte
1-Acyl-glycerol-3-phosphate acyltransferase, hepatocyte specific
"1-Acyl-sn-glycerol 3-phosphate, hepatocyte"
L-alanine/glutamine reversible exchange, blood
Fatty acid (Palmitate, n-C16:0) exchange
carnitine eicosenoyltransferase (C20:1Crn, n11)
(R)-3-Hydroxybutanoate mitochondrial transport via H+ symport
carnitine tetradecenoyltransferase (C14:1Crn, n5), mitochondrial
octadecatrienoyl carnitine transferase (C18:3Crn, n6)
pentadecanoyl carnitine transferase (C17:0CoA), mitochondrial
Phospholipase A (phosphatidylcholine), human myocyte specific
"1-Acyl-sn-glycero-3-phosphocholine, human myocyte specific"
CDP-Diacylglycerol synthetase, human myocyte
methylmalonate-semialdehyde dehydrogenase (acylating)
carbonate dehydratase (HCO3 equilibration reaction)
L-aminoadipate-semialdehyde dehydrogenase (NADH), mitochondrial
cardiolipin reversible transport, mitochondria, hepatocyte
glycerol-3-phosphate dehydrogenase (FAD), mitochondrial
pantetheine-phosphate adenylyltransferase
hydrogen peroxide mitochondrial transport
arginine mitochondrial transport via ornithine carrier
taurine transport, uniport (cytosol to peroxisome)
tetradecenoyl carnitine transport (C14:1Crn, n7)
Phosphocreatine transport to/from mitochondria via diffusion
formaldehyde transport via diffusion (mitochondrial)
stearoyl-CoA desaturase (n-C20:0CoA -> C20:1CoA, n-9)
ribose-5-phosphate isomerase, endoplasmic reticulum
CDP-Diacylglycerol synthetase, mitochondrial, human hepatocyte
acyl-coA cholesterol acyltransferase, Hepatocyte
triglycerol synthesis, endoplasmic reticulum, adipocyte
carnitine docosenoyltransferase (C22:1Crn, n9), mitochondria
Ceramide cholinephosphotransferase, human hepatocyte
glycerol 3-phosphate acyltransferase, hepatocyte specific
eicosenoyl carnitine transport (C20:1Crn, n11)
hexadecenoyl carnitinetransport (C16:1Crn, n9)
fatty-acid--CoA ligase (eicosadienoate, C20:2 n-6), hepatocyte
nucleoside-diphosphate kinase (ATP:dUDP)
D-lactate dehydrogenase, cytosolic/mitochondrial
docosapentaenoyl carnitine transport (C22:5Crn, n6)
carnitine eicosanoyltransferase (C20:0Crn)
fatty-acyl-CoA elongation (C20:2CoA, n9)
fatty-acid--CoA ligase (dodecanoate, C12:0)
phosphatidate reversible transport, mitochondrial, hepatocyte
fatty-acid--CoA ligase (tetradecenoate, C14:1 n-7)
monoacylglycerol hydrolase, human myocyte
diacylglycerol hydrolase, human adipocyte
fatty-acyl-CoA elongation (n-C20:2CoA, n6)
fatty-acid--CoA ligase (hexadecenoate, C16:1 n-9)
diacylglycerol pyrophosphate phosphatase, human adipocyte
CDP-Diacylglycerol synthetase, human hepatocyte
fatty-acid--CoA ligase (octadecadienoate, C18:3 n-6)
carnitine eicosatrienoyltransferase (C20:3Crn, n9)
L-proline transport, diffusion, mitochondrial
fatty-acid--CoA ligase (octadecenoate, C18:1 n-7)
carnitine hexadecenoyltransferase (C16:1Crn, n9), mitochondrial
carnitine docosenoyltransferase (C22:1Crn, n9)
tetradecenoyl carnitine transport (C14:1Crn, n5)
stearoyl-CoA desaturase (n-C18:0CoA -> C18:1CoA, n-5)