GENE_ASSOCIATION: NM_000143.2 GENE_LIST: NM_000143.2 SUBSYSTEM: Citrate Cycle (TCA)
methylcrotonoyl-CoA carboxylase, mitochondrial
GENE_ASSOCIATION: (NM_020166.2 and NM_022132.3) GENE_LIST: NM_020166.2 NM_022132.3 SUBSYSTEM: Valine, Leucine, and Isoleucine Degradation
L-asparagine transport in via sodium symport, blood
dimethylallyl diphosphate transport, peroxisome
eicosatrienoyl carnitine (C20:3Crn, n-6)
Nicotinamide adenine dinucleotide - reduced
GENE_ASSOCIATION: NM_002396.3 GENE_LIST: NM_002396.3 SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (NM_004563.2 or NM_001018073.1) GENE_LIST: NM_001018073.1 NM_004563.2 SUBSYSTEM: Pyruvate Metabolism
Phosphoenolpyruvate carboxykinase (GTP), mitochondrial
nucleoside-diphosphate kinase (ATP:CDP), mitochondrial
GENE_ASSOCIATION: NM_005009.2 GENE_LIST: NM_005009.2 SUBSYSTEM: Nucleotide Metabolism
C-3 sterol keto reductase (zymosterol), endoplasmic reticulum
Nicotinamide adenine dinucleotide phosphate
Nicotinamide adenine dinucleotide phosphate - reduced
Palmitoyl-CoA desaturase (n-C17:0CoA -> C17:1CoA, n-8)
GENE_ASSOCIATION: (NM_005063.4 or NM_024906.1 or NM_001037582.1) GENE_LIST: NM_001037582.1 NM_005063.4 NM_024906.1 SUBSYSTEM: Fatty Acid Desaturation
GENE_ASSOCIATION: (NM_013328.2 or NM_023078.1) GENE_LIST: NM_013328.2 NM_023078.1 SUBSYSTEM: Proline Metabolism
GENE_ASSOCIATION: NM_004104.4 GENE_LIST: NM_004104.4 SUBSYSTEM: Fatty Acid Biosynthesis
GENE_ASSOCIATION: NM_001609.2 GENE_LIST: NM_001609.2 SUBSYSTEM: Valine, Leucine, and Isoleucine Degradation
GENE_ASSOCIATION: NM_000365.4 GENE_LIST: NM_000365.4 SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: NM_015922.1 GENE_LIST: NM_015922.1 SUBSYSTEM: Cholesterol Biosynthesis
C-3 sterol dehydrogenase NADPH, (4-methylzymosterol)
GENE_ASSOCIATION: NM_002631.2 GENE_LIST: NM_002631.2 SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: NM_001752.2 GENE_LIST: NM_001752.2 SUBSYSTEM: Other
GENE_ASSOCIATION: NM_000187.2 GENE_LIST: NM_000187.2 SUBSYSTEM: Tyrosine metabolism
fatty-acid--CoA ligase (eicosatetraenoate, C20:4 n-6)
GENE_ASSOCIATION: NM_004577.3 GENE_LIST: NM_004577.3 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
SUBSYSTEM: Valine, Leucine, and Isoleucine Degradation
GENE_ASSOCIATION: NM_000098.1 GENE_LIST: NM_000098.1 SUBSYSTEM: Carnitine Shuttle
carnitine eicosadienoyltransferase (C20:2Crn, n6), mitochondrial
carnitine pentadecanoyltransferase (C15:0Crn)
GENE_ASSOCIATION: NM_144563.2 GENE_LIST: NM_144563.2 SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: NM_000277.1 GENE_LIST: NM_000277.1 SUBSYSTEM: Phenylalanine, Tyrosine, and Tryptophan Biosynthesis
fatty-acid--CoA ligase (ocosatetraenoate, C22:4 n-6)
GENE_ASSOCIATION: NM_001190.2 GENE_LIST: NM_001190.2 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
glutamate aspartate carrier, cytosolic/mitochondrial
GENE_ASSOCIATION: (NM_014251.2 or NM_003705.2) GENE_LIST: NM_003705.2 NM_014251.2 SUBSYSTEM: Transport, Mitochondrial
GENE_ASSOCIATION: NM_002079.1 GENE_LIST: NM_002079.1 SUBSYSTEM: Alanine and Aspartate Metabolism
GENE_ASSOCIATION: (NM_005415.3 or NM_006749.3) GENE_LIST: NM_005415.3 NM_006749.3 SUBSYSTEM: Transport, Extracellular
phosphate transport in/out via proton symporter
GENE_ASSOCIATION: NM_006636.3 GENE_LIST: NM_006636.3
methylenetetrahydrofolate dehydrogenase (NAD), mitochondrial
GENE_ASSOCIATION: NM_001467.3 GENE_LIST: NM_001467.3 SUBSYSTEM: Transport, Endoplasmic Reticular
glucose 6-phosphate endoplasmic reticular transport via diffusion
fatty-acid--CoA ligase (eicosenoate, C20:1 n-9)
nucleoside-diphosphate kinase (ATP:dADP)
GENE_ASSOCIATION: NM_002395.2 GENE_LIST: NM_002395.2 SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: NM_005276.2 GENE_LIST: NM_005276.2 SUBSYSTEM: Glycerophospholipid Metabolism
glycerol-3-phosphate dehydrogenase (NAD)
Octadecanoate (n-C18:0) transport in via uniport
L-phenylalanine transport via diffusion (extracellular to cytosol)
GENE_ASSOCIATION: (NM_005271.1 or NM_012084.3) GENE_LIST: NM_005271.1 NM_012084.3 SUBSYSTEM: Glutamate Metabolism
glutamate dehydrogenase (NADP), mitochondrial
carnitine tetradecenoyltransferase (C14:1Crn, n5), mitochondrial
GENE_ASSOCIATION: (NM_005628.1 or NM_018018.2) GENE_LIST: NM_005628.1 NM_018018.2 SUBSYSTEM: Transport, Extracellular
L-glutamine reversible transport via sodium symport, blood
aldehyde dehydrogenase (NAD), mitochondrial
GENE_ASSOCIATION: (NM_000692.3 or NM_000690.2) GENE_LIST: NM_000690.2 NM_000692.3 SUBSYSTEM: Valine, Leucine, and Isoleucine Degradation
GENE_ASSOCIATION: (NM_002860.3 or NM_001017423.1) GENE_LIST: NM_001017423.1 NM_002860.3 SUBSYSTEM: Arginine and Proline Metabolism
GENE_ASSOCIATION: (NM_020244.2 or NM_006090.3 or NM_001007794.1) GENE_LIST: NM_001007794.1 NM_006090.3 NM_020244.2 SUBSYSTEM: Phospholipid Metabolism
diacylglycerol cholinephosphotransferase, human adipocyte
GENE_ASSOCIATION: NM_012190.2 GENE_LIST: NM_012190.2 SUBSYSTEM: Folate Metabolism
fatty-acid--CoA ligase (octadecadienoate, C18:2 n-6)
carnitine hexadecenoyltransferase (C16:1Crn, n7)
phosphoribosylformylglycinamidine synthase
GENE_ASSOCIATION: NM_012393.1 GENE_LIST: NM_012393.1 SUBSYSTEM: Nucleotide Metabolism
GENE_ASSOCIATION: (NM_006621.3 or NM_015328.1 or NM_000687.1) GENE_LIST: NM_000687.1 NM_006621.3 NM_015328.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: NM_000637.2 GENE_LIST: NM_000637.2 SUBSYSTEM: Cysteine Metabolism
GENE_ASSOCIATION: (NM_018290.2 or NM_002633.2) GENE_LIST: NM_002633.2 NM_018290.2 SUBSYSTEM: Glycogen Metabolism
GENE_ASSOCIATION: NM_001159.3 GENE_LIST: NM_001159.3 SUBSYSTEM: Valine, Leucine, and Isoleucine Degradation
L-glutamate reversible transport via proton symport, mitochondrial
GENE_ASSOCIATION: (NM_031481.1 or NM_024698.4) GENE_LIST: NM_024698.4 NM_031481.1 SUBSYSTEM: Transport, Mitochondrial
GENE_ASSOCIATION: NM_004104.4 GENE_LIST: NM_004104.4 SUBSYSTEM: Fatty acid activation
ocosatetraenoyl carnitine (C22:4Crn, n-6)
carnitine ocosatetraenoyltransferase (C22:4Crn, n6)
GENE_ASSOCIATION: (NM_018018.2 or NM_007231.1 or NM_018976.3) GENE_LIST: NM_007231.1 NM_018018.2 NM_018976.3 SUBSYSTEM: Transport, Extracellular
L-histidine transport in via sodium symport, blood
docosahexaenoyl carnitine (C22:6Crn, n-3)
carnitine docosahexaenoyltransferase (C22:6Crn, n3)
GENE_ASSOCIATION: (NM_004265.2 or NM_021727.3) GENE_LIST: NM_004265.2 NM_021727.3 SUBSYSTEM: Fatty Acid Synthesis
stearoyl-CoA desaturase (C18:3CoA, n3 -> C18:4CoA, n3)
octadecadienoyl carnitine (C18:2Crn, n-6)
Nucleoside triphosphate pyrophosphorylase (atp)
GENE_ASSOCIATION: (NM_001042351.1 or NM_000402.2) GENE_LIST: NM_000402.2 NM_001042351.1 SUBSYSTEM: Pentose Phosphate Pathway
alphaketobutyrate transport (mitochondrial)
GENE_ASSOCIATION: (NM_000387.3 or NM_001039355.1) GENE_LIST: NM_000387.3 NM_001039355.1 SUBSYSTEM: Carnitine Shuttle
docosapentaenoyl carnitine (C22:5Crn, n-3)
docosapentaenoyl carnitine transport (C22:5Crn, n3)
Phosphatidylglycerophosphate, human adipocyte
eicosenoyl carnitine transport (C20:1Crn, n11)
GENE_ASSOCIATION: NM_002079.1 GENE_LIST: NM_002079.1 SUBSYSTEM: Asparagine Metabolism
phosphatidyl-1D-myo-inositol, human adipocyte
fatty-acid--CoA ligase (dodecanoate, C12:0)
GENE_ASSOCIATION: NM_000026.1 GENE_LIST: NM_000026.1 SUBSYSTEM: Nucleotide Metabolism
Glutamine transport, proton coupled, mitochondria
isopentenyl diphosphate transport, peroxisome
GENE_ASSOCIATION: (NM_175085.1 or NM_000819.3) GENE_LIST: NM_000819.3 NM_175085.1 SUBSYSTEM: Nucleotide Metabolism
phosphoribosylglycinamide formyltransferase, irreversible
GENE_ASSOCIATION: (NM_032564.2 or NM_178176.2 or NM_012079.3) GENE_LIST: NM_012079.3 NM_032564.2 NM_178176.2 SUBSYSTEM: Triacylglycerol Synthesis
triglycerol synthesis, endoplasmic reticulum, adipocyte
carnitine tetradecanoyltransferase (C14:0Crn, mitochondria
eicosatetraenoyl carnitine (C20:4Crn, n-6)
GENE_ASSOCIATION: NM_000137.1 GENE_LIST: NM_000137.1 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (NM_001039355.1 or NM_000387.3) GENE_LIST: NM_000387.3 NM_001039355.1 SUBSYSTEM: Carnitine Shuttle
ocosatetraenoyl carnitine transport (C22:4Crn, n6)
phosphomevalonate kinase, reversible, peroxisome
GENE_ASSOCIATION: NM_006556.2 GENE_LIST: NM_006556.2 SUBSYSTEM: Cholesterol Metabolism
carnitine docosahexaenoyltransferase (C22:6Crn, n3), mitochondrial
GENE_ASSOCIATION: (NM_138733.2 or NM_000291.2) GENE_LIST: NM_000291.2 NM_138733.2 SUBSYSTEM: Glycolysis/Gluconeogenesis
alcohol dehydrogenase (ethanol, NADP), forward reaction
GENE_ASSOCIATION: (NM_153326.1 or NM_006066.2) GENE_LIST: NM_006066.2 NM_153326.1 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (NM_014905.2 or NM_013267.2) GENE_LIST: NM_013267.2 NM_014905.2 SUBSYSTEM: Glutamate Metabolism
GENE_ASSOCIATION: NM_005984.1 GENE_LIST: NM_005984.1 SUBSYSTEM: Transport, Mitochondrial
(S)-Methylmalonate semialdehyde transport, mitochondrial
GENE_ASSOCIATION: NM_012140.3 GENE_LIST: NM_012140.3 SUBSYSTEM: Transport, Mitochondrial
SUBSYSTEM: Transport, Endoplasmic Reticular
carnitine palmitoyltransferase (C16:0Crn), mitochondrial
octadecenoyl carnitine transport (C18:1Crn, n9)
acetate mitochondrial transport via proton symport
glycine reversible transport via sodium symport, blood
GENE_ASSOCIATION: NM_021823.3 GENE_LIST: NM_021823.3 SUBSYSTEM: CoA Biosynthesis
phosphopantothenoylcysteine decarboxylase
fatty-acid--CoA ligase (octadecenoate, C18:1 n-5)
hydrogen peroxide mitochondrial transport
GENE_ASSOCIATION: (NM_000019.2 or (NM_000182.3 and NM_000183.1)) GENE_LIST: NM_000019.2 NM_000182.3 NM_000183.1 SUBSYSTEM: Tryptophan metabolism
acetyl-CoA C-acetyltransferase, mitochondrial
GENE_ASSOCIATION: NM_004341.3 GENE_LIST: NM_004341.3 SUBSYSTEM: Nucleotide Metabolism
Oleoyl-CoA desaturase (C18:2CoA, n6 -> C18:3CoA, n6)
This model is from the article: A multi-tissue type genome-scale metabolic network for analysis of whole-body systems physiology. Bordbar A, Feist AM, Usaite-Black R, Woodcock J, Palsson BO, Famili I. BMC Syst Biol. 2011 Oct 31;5(1):180. 22041191 , Abstract: ABSTRACT: BACKGROUND: Genome-scale metabolic reconstructions provide a biologically meaningful mechanis tic basis for the genotype-phenotype relationship. The global human metabolic net work, termed Recon 1, has recently been reconstructed allowing the systems analys is of human metabolic physiology and pathology. Utilizing high-throughput data, R econ 1 has recently been tailored to different cells and tissues, including the l iver, kidney, brain, and alveolar macrophage. These models have shown utility in the study of systems medicine. However, no integrated analysis between human tiss ues has been done. RESULTS: To describe tissue-specific functions, Recon 1 was tailored to describe metabolis m in three human cells: adipocytes, hepatocytes, and myocytes. These cell-specifi c networks were manually curated and validated based on known cellular metabolic functions. To study intercellular interactions, a novel multi-tissue type modelin g approach was developed to integrate the metabolic functions for the three cell types, and subsequently used to simulate known integrated metabolic cycles. In ad dition, the multi-tissue model was used to study diabetes: a pathology with syste mic properties. High-throughput data was integrated with the network to determine differential metabolic activity between obese and type II obese gastric bypass p atients in a whole-body context. CONCLUSION: The multi-tissue type modeling approach presented provides a platform to study in tegrated metabolic states. As more cell and tissue-specific models are released, it is critical to develop a framework in which to study their interdependencies. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
carnitine eicosatetraenoyltransferase (C20:4Crn, n6)
carnitine eicosatrienoyltransferase (C20:3Crn, n6), mitochondrial
dodecanoyl carnitine transport (C12:0Crn)
fatty-acid--CoA ligase (octadecenoate, C18:1 n-9)
GENE_ASSOCIATION: NM_001807.3 GENE_LIST: NM_001807.3 SUBSYSTEM: Triglycerol Degradation
triacylglycerol hydrolase, human myocyte
GENE_ASSOCIATION: NM_001801.2 GENE_LIST: NM_001801.2 SUBSYSTEM: Cysteine Metabolism
GENE_ASSOCIATION: NM_130767.2 GENE_LIST: NM_130767.2 SUBSYSTEM: Pyruvate Metabolism
sodium transport in/out via proton antiport (one H+), blood
GENE_ASSOCIATION: (NM_001151.2 or NM_001636.1 or NM_001152.1) GENE_LIST: NM_001151.2 NM_001152.1 NM_001636.1 SUBSYSTEM: Transport, Mitochondrial
GENE_ASSOCIATION: NM_002591.2 GENE_LIST: NM_002591.2 SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (NM_005063.4 or NM_001037582.1 or NM_024906.1) GENE_LIST: NM_001037582.1 NM_005063.4 NM_024906.1 SUBSYSTEM: Fatty Acid Desaturation
Palmitoyl-CoA desaturase (n-C16:0CoA -> C16:1CoA, n-7)
inorganic diphosphatase, endoplasmic reticulum
fatty-acyl-CoA elongation (C22:5CoA, n3)
carnitine eicosenoyltransferase (C20:1Crn, n9), mitochondrial
Hydroxymethylglutaryl-CoA reversible mitochondrial transport
eicosatrienoyl carnitine transport (C20:3Crn, n6)
GENE_ASSOCIATION: NM_004104.4 GENE_LIST: NM_004104.4 SUBSYSTEM: Fatty acid elongation
acetate transport in/out via proton symport
Octadecatrienoate (C18:3, n-3) transport
GENE_ASSOCIATION: NM_014595.1 GENE_LIST: NM_014595.1 SUBSYSTEM: Nucleotide Metabolism
eicosatetraenoyl carnitine transport (C20:4Crn, n6)
GENE_ASSOCIATION: NM_003051.3 GENE_LIST: NM_003051.3 SUBSYSTEM: Transport, Mitochondrial
acetoacetate transport via proton symport, mitochondrial
GENE_ASSOCIATION: (NM_000429.2 or (NM_005911.4 and NM_182796.1) or (NM_005911.4 and NM_013283.3)) GENE_LIST: NM_000429.2 NM_005911.4 NM_013283.3 NM_182796.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
stearoyl-CoA desaturase (n-C22:0CoA -> C22:1CoA, n-9)
phosphoribosylaminoimidazole carboxylase
GENE_ASSOCIATION: NM_003562.3 GENE_LIST: NM_003562.3 SUBSYSTEM: Transport, Mitochondrial
carnitine docosenoyltransferase (C22:1Crn, n9), mitochondria
2-oxoglutarate dehydrogenase, mitochondrial
fatty-acid--CoA ligase (eicosanoate, C20:0)
fatty acid transport via diffusion, blood
carnitine eicosenoyltransferase (C20:1Crn, n11)
carnitine eicosatetraenoyltransferase (C20:4Crn, n6), mitochondrial
GENE_ASSOCIATION: NM_001169.2 GENE_LIST: NM_001169.2 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: NM_021095.1 GENE_LIST: NM_021095.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: NM_002150.2 GENE_LIST: NM_002150.2 SUBSYSTEM: Tyrosine metabolism
eicosenoyl carnitine transport (C20:1Crn, n9)
dodecanoate (C12:0) mammalian cell transport
GENE_ASSOCIATION: NM_207315.1 GENE_LIST: NM_207315.1 SUBSYSTEM: Nucleotide Metabolism
GENE_ASSOCIATION: (NM_006745.3 or NM_001017369.1) GENE_LIST: NM_001017369.1 NM_006745.3 SUBSYSTEM: Cholesterol Metabolism
glycerol-3-phosphate transport, mitochondrial
GENE_ASSOCIATION: (NM_139274.1 or NM_018677.2 or NM_023928.2) GENE_LIST: NM_018677.2 NM_023928.2 NM_139274.1 SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: NM_000431.1 GENE_LIST: NM_000431.1 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: NM_032501.2 GENE_LIST: NM_032501.2 SUBSYSTEM: Fatty acid activation
GENE_ASSOCIATION: (NM_016308.1 or NM_012145.2) GENE_LIST: NM_012145.2 NM_016308.1 SUBSYSTEM: Nucleotide Metabolism
GENE_ASSOCIATION: (NM_001077447.1 or NM_024664.2) GENE_LIST: NM_001077447.1 NM_024664.2 SUBSYSTEM: CoA Biosynthesis
bicarbonate transport (Na/HCO3 cotransport), blood
octadecatrienoyl carnitine (C18:3Crn, n3)
fatty-acid--CoA ligase (docosahexaenoate, C22:6 n-3)
L-2-amino-3-oxobutanoate decarboxylation, mitochondrial
SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
Tetradecanoate (n-C14:0) transport in via uniport
GENE_ASSOCIATION: (NM_032136.3 or NM_012253.2 or NM_001064.1) GENE_LIST: NM_001064.1 NM_012253.2 NM_032136.3 SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: NM_012088.2 GENE_LIST: NM_012088.2 SUBSYSTEM: Pentose Phosphate Pathway
methylenetetrahydrofolate dehydrogenase (NADP), mitochondrial
GENE_ASSOCIATION: (NM_006759.3 or NM_001001521.1) GENE_LIST: NM_001001521.1 NM_006759.3 SUBSYSTEM: Glycogen Metabolism
UTP-glucose-1-phosphate uridylyltransferase
fatty-acid--CoA ligase (heptadecenoate, C17:1 n-8)
carnitine hexadecenoyltransferase (C16:1Crn, n9)
glyceraldehyde-3-phosphate dehydrogenase (NAD)
GENE_ASSOCIATION: (NM_014364.3 or NM_002046.3) GENE_LIST: NM_002046.3 NM_014364.3 SUBSYSTEM: Glycolysis/Gluconeogenesis
L-cysteine reversible transport via sodium symport, reversible, blood
GENE_ASSOCIATION: (NM_198324.1 or NM_004077.2) GENE_LIST: NM_004077.2 NM_198324.1 SUBSYSTEM: Citrate Cycle (TCA)
GENE_ASSOCIATION: NM_000255.1 GENE_LIST: NM_000255.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Degradation
carnitine octadecenoyltransferase (C18:1Crn, n9)
fatty-acyl-CoA elongation (n-C20:3CoA, n6)
Palmitoyl-CoA desaturase (n-C16:0CoA -> C16:1CoA, n-9)
GENE_ASSOCIATION: (NM_030674.2 or NM_018976.3 or NM_001077484.1) GENE_LIST: NM_001077484.1 NM_018976.3 NM_030674.2 SUBSYSTEM: Transport, Extracellular
stearoyl-CoA desaturase (n-C20:0CoA -> C20:1CoA, n-9)
GENE_ASSOCIATION: NM_032601.2 GENE_LIST: NM_032601.2 SUBSYSTEM: Valine, Leucine, and Isoleucine Degradation
methylmalonyl-CoA epimerase, mitochondrial
carnitine docosenoyltransferase (C22:1Crn, n9)
GENE_ASSOCIATION: (NM_032136.3 or NM_001064.1 or NM_012253.2) GENE_LIST: NM_001064.1 NM_012253.2 NM_032136.3 SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: (NM_006133.1 or NM_139179.1) GENE_LIST: NM_006133.1 NM_139179.1 SUBSYSTEM: Triglycerol Degradation
diacylglycerol hydrolase, human adipocyte
GENE_ASSOCIATION: (NM_000161.2 or NM_001024024.1) GENE_LIST: NM_000161.2 NM_001024024.1 SUBSYSTEM: Tetrahydrobiopterin
2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate
glutamate-5-semialdehyde dehydrogenase, mitochondrial
carnitine octadecenoyltransferase (C18:1Crn, n5), mitochondrial
stearoyl-CoA desaturase (n-C20:0CoA -> C20:1CoA, n-11)
SUBSYSTEM: Glycine and Serine Metabolism
carnitine eicosadienoyltransferase (C20:2Crn, n6)
eicosadienoyl carnitine transport (C20:2Crn, n6)
GENE_ASSOCIATION: (NM_152328.3 or NM_199165.1 or NM_001126.2) GENE_LIST: NM_001126.2 NM_152328.3 NM_199165.1 SUBSYSTEM: Nucleotide Metabolism
octadecadienoyl carnitine transferase (C18:2Crn, n6)
GENE_ASSOCIATION: (NM_005309.1 or NM_133443.1) GENE_LIST: NM_005309.1 NM_133443.1 SUBSYSTEM: Alanine and Aspartate Metabolism
GENE_ASSOCIATION: (NM_003676.2 or NM_144780.1 or NM_206918.1) GENE_LIST: NM_003676.2 NM_144780.1 NM_206918.1 SUBSYSTEM: Phospholipid Metabolism
SUBSYSTEM: Vitamins & Cofactor Biosynthesis
GENE_ASSOCIATION: (NM_198830.1 or NM_001096.2) GENE_LIST: NM_001096.2 NM_198830.1 SUBSYSTEM: Central Metabolism
GENE_ASSOCIATION: NM_032501.2 GENE_LIST: NM_032501.2 SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: NM_024419.3 GENE_LIST: NM_024419.3 SUBSYSTEM: Phospholipid Metabolism
CDP-diacylglycerol--serine O-phosphatidyltransferae, mitochondrial, human adipoctye
Eicosatetraenoate (C20:4, n-6) transport
GENE_ASSOCIATION: NM_014338.3 GENE_LIST: NM_014338.3 SUBSYSTEM: Phospholipid Metabolism
phosphatidylethanolamine, human adipoctye
phosphatidylserine decarboxylase, human adipocyte
Squalene epoxidase, endoplasmic reticular
GENE_ASSOCIATION: NM_003129.3 GENE_LIST: NM_003129.3 SUBSYSTEM: Cholesterol Metabolism
nucleoside-diphosphate kinase (ATP:dGDP)
GENE_ASSOCIATION: NM_002079.1 GENE_LIST: NM_002079.1 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: NM_000071.1 GENE_LIST: NM_000071.1 SUBSYSTEM: Cysteine Metabolism
fatty-acid--CoA ligase (eicosatrienoate, C20:3 n-6), hepatocyte
GENE_ASSOCIATION: NM_001071.1 GENE_LIST: NM_001071.1 SUBSYSTEM: Nucleotide Metabolism
carnitine O-aceyltransferase, mitochondrial
L-Glutamate 5-semialdehyde transport, mitochondrial
tetradecenoyl carnitine transport (C14:1Crn, n5)
octadecatrienoyl carnitine transferase (C18:3Crn, n3)
GENE_ASSOCIATION: NM_003627.4 GENE_LIST: NM_003627.4 SUBSYSTEM: Transport, Extracellular
L-isoleucine transport via diffusion, blood
GENE_ASSOCIATION: (NM_000507.2 or NM_003837.2) GENE_LIST: NM_000507.2 NM_003837.2 SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: NM_002004.2 GENE_LIST: NM_002004.2 SUBSYSTEM: Cholesterol Biosynthesis
GENE_ASSOCIATION: NM_006579.1 GENE_LIST: NM_006579.1 SUBSYSTEM: Cholesterol Biosynthesis
fatty-acid--CoA ligase (hexadecenoate, C16:1 n-9)
GENE_ASSOCIATION: NM_001263.2 GENE_LIST: NM_001263.2 SUBSYSTEM: Phospholipid Metabolism
CDP-Diacylglycerol synthetase, human adipocyte
carnitine eicosanoyltransferase (C20:0Crn)
GENE_ASSOCIATION: (NM_203391.1 or NM_000167.3 or NM_033214.2) GENE_LIST: NM_000167.3 NM_033214.2 NM_203391.1 SUBSYSTEM: Glycerophospholipid Metabolism
glucose transport (uniport: facilitated diffusion)
carnitine octadecenoyltransferase (C18:1Crn, n7), mitochondrial
GENE_ASSOCIATION: NM_000274.1 GENE_LIST: NM_000274.1 SUBSYSTEM: Arginine and Proline Metabolism
carnitine octadecenoyltransferase (C18:1Crn, n9), mitochondrial
carnitine ocosatetraenoyltransferase (C22:4Crn, n6), mitochondrial
pantetheine-phosphate adenylyltransferase
GENE_ASSOCIATION: NM_005918.2 GENE_LIST: NM_005918.2 SUBSYSTEM: Citrate Cycle (TCA)
ribonucleoside-diphosphate reductase (GDP)
GENE_ASSOCIATION: ((NM_001033.2 and NM_001034.1) and NM_003329.2) GENE_LIST: NM_001033.2 NM_001034.1 NM_003329.2 SUBSYSTEM: Nucleotide Metabolism
CDP-Diacylglycerol synthetase, mitochondrial, human adipocyte
GENE_ASSOCIATION: NM_003818.2 GENE_LIST: NM_003818.2 SUBSYSTEM: Phospholipid Metabolism
lathosterol oxidase (NAD), endoplasmic reticulum
GENE_ASSOCIATION: (NM_006918.3 or NM_001024956.1) GENE_LIST: NM_001024956.1 NM_006918.3 SUBSYSTEM: Cholesterol Biosynthesis
carnitine octadecadienoyltransferase (C18:2Crn, n6)
GENE_ASSOCIATION: (NM_001122633.1 or NM_001122634.1 or NM_001875.2) GENE_LIST: NM_001122633.1 NM_001122634.1 NM_001875.2 SUBSYSTEM: Arginine and Proline Metabolism
carnitine octadecadienoyltransferase (C18:2Crn, n6), mitochondrial
glutamine phosphoribosyldiphosphate amidotransferase
GENE_ASSOCIATION: NM_002703.3 GENE_LIST: NM_002703.3 SUBSYSTEM: Purine and Pyrimidine Biosynthesis
aspartate carbamoyltransferase (reversible)
cytochrome c oxidase (mitochondrial 4 protons/4 cyto)
GENE_ASSOCIATION: (NM_199292.2 or NM_199293.2 or NM_000360.3) GENE_LIST: NM_000360.3 NM_199292.2 NM_199293.2 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: NM_000175.2 GENE_LIST: NM_000175.2 SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (NM_145871.1 or NM_001513.2 or NM_145870.1) GENE_LIST: NM_001513.2 NM_145870.1 NM_145871.1 SUBSYSTEM: Tyrosine metabolism
glycine C-acetyltransferase, mitochondrial
GENE_ASSOCIATION: NM_014291.2 GENE_LIST: NM_014291.2 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
fatty-acyl-CoA elongation (C22:4CoA, n6)
GENE_ASSOCIATION: ((NM_000182.3 and NM_000183.1) or NM_004092.2) GENE_LIST: NM_000182.3 NM_000183.1 NM_004092.2 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
GENE_ASSOCIATION: NM_006843.2 GENE_LIST: NM_006843.2 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
1-Acyl-sn-glycerol 3-phosphate, adipocyte
1-Acyl-glycerol-3-phosphate acyltransferase, adipocyte specific
GENE_ASSOCIATION: NM_001905.1 GENE_LIST: NM_001905.1 SUBSYSTEM: Nucleotide Metabolism
stearoyl-CoA desaturase (n-C18:0CoA -> C18:1CoA, n-5)
GENE_ASSOCIATION: (NM_004169.3 or NM_148918.1) GENE_LIST: NM_004169.3 NM_148918.1 SUBSYSTEM: Serine metabolism
GENE_ASSOCIATION: (NM_016321.1 or NM_020407.1 or NM_000324.1) GENE_LIST: NM_000324.1 NM_016321.1 NM_020407.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (NM_019857.3 or NM_175859.1) GENE_LIST: NM_019857.3 NM_175859.1 SUBSYSTEM: Pyrimidine Biosynthesis
fatty-acyl-CoA elongation (C20:4CoA, n3)
HCO3 equilibration reaction, mitochondrial
GENE_ASSOCIATION: (NM_001739.1 or NM_007220.2) GENE_LIST: NM_001739.1 NM_007220.2 SUBSYSTEM: Central Metabolism
GENE_ASSOCIATION: NM_001360.1 GENE_LIST: NM_001360.1 SUBSYSTEM: Cholesterol Metabolism
L-glutamate 5-semialdehyde dehydratase (spontaneous)
GENE_ASSOCIATION: NM_006623.2 GENE_LIST: NM_006623.2 SUBSYSTEM: Amino Acid Metabolism
GENE_ASSOCIATION: (NM_013328.2 or NM_023078.1) GENE_LIST: NM_013328.2 NM_023078.1 SUBSYSTEM: Amino Acid Metabolism
GENE_ASSOCIATION: NM_000696.2 GENE_LIST: NM_000696.2 SUBSYSTEM: Cholesterol Metabolism
aldehyde dehydrogenase (acetaldehyde, NAD)
octadecenoyl carnitine transport (C18:1Crn, n5)
6-Phospho-D-gluconate transport in/out via proton symport
cytochrome P450 lanosterol 14-alpha-demethylase
GENE_ASSOCIATION: NM_000786.2 GENE_LIST: NM_000786.2 SUBSYSTEM: Cholesterol Biosynthesis
GENE_ASSOCIATION: NM_004044.4 GENE_LIST: NM_004044.4 SUBSYSTEM: Nucleotide Metabolism
GENE_ASSOCIATION: NM_021814.3 GENE_LIST: NM_021814.3 SUBSYSTEM: Fatty acid elongation
fatty-acyl-CoA elongation (n-C20:2CoA, n6)
GENE_ASSOCIATION: NM_012145.2 GENE_LIST: NM_012145.2 SUBSYSTEM: Nucleotide Metabolism
ribonucleoside-diphosphate reductase (ADP)
GENE_ASSOCIATION: NM_001098.2 GENE_LIST: NM_001098.2 SUBSYSTEM: Citrate Cycle (TCA)
carnitine O-palmitoyltransferase (C16:0Crn)
carbamoyl-phosphate synthase (glutamine-hydrolysing)
GENE_ASSOCIATION: NM_016308.1 GENE_LIST: NM_016308.1 SUBSYSTEM: Nucleotide Metabolism
6-phosphogluconolactonase, endoplasmic reticulum
GENE_ASSOCIATION: NM_004285.3 GENE_LIST: NM_004285.3 SUBSYSTEM: Pentose Phosphate Pathway
lathosterol oxidase (NADP), endoplasmic reticulum
GENE_ASSOCIATION: (NM_001098272.1 or NM_002130.4) GENE_LIST: NM_001098272.1 NM_002130.4 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: NM_005518.2 GENE_LIST: NM_005518.2 SUBSYSTEM: Cholesterol Metabolism
glutamate dehydrogenase (NAD), mitochondrial
GENE_ASSOCIATION: NM_013402.3 GENE_LIST: NM_013402.3 SUBSYSTEM: Fatty Acid Synthesis
fatty acyl-CoA desaturase (C20:3CoA, n6 -> C20:4CoA, n6)
5,6,7,8-Tetrahydrofolate transport, diffusion, mitochondrial
GENE_ASSOCIATION: (NM_001902.4 or NM_153742.3) GENE_LIST: NM_001902.4 NM_153742.3 SUBSYSTEM: Cysteine Metabolism
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
GENE_ASSOCIATION: (NM_014362.2 or NM_198047.1) GENE_LIST: NM_014362.2 NM_198047.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Degradation
GENE_ASSOCIATION: NM_002168.2 GENE_LIST: NM_002168.2 SUBSYSTEM: Citrate Cycle (TCA)
fatty-acid--CoA ligase (hexadecenoate, C16:1 n-7)
carnitine docosapentaenoyltransferase (C22:5Crn, n3), mitochondrial
fatty-acid--CoA ligase (heptadecanoate, C15:0)
GENE_ASSOCIATION: (NM_000436.2 or NM_022120.1) GENE_LIST: NM_000436.2 NM_022120.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Degradation
GENE_ASSOCIATION: NM_014762.2 GENE_LIST: NM_014762.2 SUBSYSTEM: Cholesterol Metabolism
formimidoyltetrahydrofolate cyclodeaminase
GENE_ASSOCIATION: (NM_006657.2 or NM_206965.1) GENE_LIST: NM_006657.2 NM_206965.1 SUBSYSTEM: Histidine Degradation
eicosanoyl carnitine transport (C20:0Crn)
GENE_ASSOCIATION: (NM_004508.2 or NM_033261.2) GENE_LIST: NM_004508.2 NM_033261.2 SUBSYSTEM: Cholesterol Metabolism
isopentenyl-diphosphate D-isomerase, peroxisomal
3',5'-cyclic-nucleotide phosphodiesterase
Ornithine/citrulline antiport, mitocondiral
GENE_ASSOCIATION: (NM_014252.2 or NM_031947.2) GENE_LIST: NM_014252.2 NM_031947.2 SUBSYSTEM: Transport, Mitochondrial
GENE_ASSOCIATION: NM_000791.3 GENE_LIST: NM_000791.3 SUBSYSTEM: Folate Metabolism
GENE_ASSOCIATION: NM_004462.3 GENE_LIST: NM_004462.3 SUBSYSTEM: Cholesterol Metabolism
Squalene synthase, endoplasmic reticulum
stearoyl-CoA desaturase (n-C18:0CoA -> C18:1CoA, n-7)
phosphate transporter, endoplasmic reticulum
GENE_ASSOCIATION: (NM_006632.3 or NM_001098486.1 or NM_020309.2) GENE_LIST: NM_001098486.1 NM_006632.3 NM_020309.2 SUBSYSTEM: Transport, Endoplasmic Reticular
carbonate dehydratase (HCO3 equilibration reaction)
Ceramide cholinephosphotransferase, adipocyte
GENE_ASSOCIATION: (NM_002863.3 or NM_002862.3 or NM_005609.1) GENE_LIST: NM_002862.3 NM_002863.3 NM_005609.1 SUBSYSTEM: Glycogen Metabolism
carnitine tetradecenoyltransferase (C14:1Crn, n5)
L-methionine transport in via sodium symport, blood
GENE_ASSOCIATION: NM_018960.4 GENE_LIST: NM_018960.4 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (NM_054012.2 or NM_000050.3) GENE_LIST: NM_000050.3 NM_054012.2 SUBSYSTEM: Urea Cycle
GENE_ASSOCIATION: NM_003051.3 GENE_LIST: NM_003051.3 SUBSYSTEM: Pyruvate Metabolism
C-4 sterol methyl oxidase (4,4-dimethylzymosterol), endoplasmic reticulum
GENE_ASSOCIATION: (NM_001017369.1 or NM_006745.3) GENE_LIST: NM_001017369.1 NM_006745.3 SUBSYSTEM: Cholesterol Biosynthesis
GENE_ASSOCIATION: NM_003258.1 GENE_LIST: NM_003258.1 SUBSYSTEM: Nucleotide Metabolism
carnitine eicosatrienoyltransferase (C20:3Crn, n6)
GENE_ASSOCIATION: NM_002197.1 GENE_LIST: NM_002197.1 SUBSYSTEM: Citrate Cycle (TCA)
GENE_ASSOCIATION: NM_003124.3 GENE_LIST: NM_003124.3 SUBSYSTEM: Folate Metabolism
octadecenoyl carnitine transferase (C18:1Crn, n7)
C-3 sterol dehydrogenase NADH, (4-methylzymosterol)
octadecanoyl carnitine transport (C18:0Crn)
GENE_ASSOCIATION: (NM_032717.3 or NM_020918.2) GENE_LIST: NM_020918.2 NM_032717.3 SUBSYSTEM: Phospholipid Metabolism
glycerol 3-phosphate acyltransferase, adipocyte specific
carnitine dodecanoyltransferase (C12:0Crn), mitochondria
fatty-acid--CoA ligase (heptadecanoate, C17:0)
fatty acyl-CoA desaturase (C22:5CoA, n3 -> C22:6CoA, n3)
GENE_ASSOCIATION: NM_000320.1 GENE_LIST: NM_000320.1 SUBSYSTEM: Tyrosine metabolism
glycine passive transport to mitochondria
fatty-acid--CoA ligase (octadecenoate, C18:1 n-7)
GENE_ASSOCIATION: NM_000373.1 GENE_LIST: NM_000373.1 SUBSYSTEM: Nucleotide Metabolism
CO2 transport (diffusion), mitochondrial
carnitine eicosenoyltransferase (C20:1Crn, n11), mitochondrial
GENE_ASSOCIATION: (NM_018018.2 or NM_005628.1 or NM_003038.2) GENE_LIST: NM_003038.2 NM_005628.1 NM_018018.2 SUBSYSTEM: Transport, Extracellular
fatty-acid--CoA ligase (docosanoate, C22:0)
5,10-Methylenetetrahydrofolate transport, diffusion, mitochondrial
asparagine synthase (glutamine-hydrolysing)
GENE_ASSOCIATION: (NM_001673.2 or NM_133436.1 or NM_183356.1) GENE_LIST: NM_001673.2 NM_133436.1 NM_183356.1 SUBSYSTEM: Alanine and Aspartate Metabolism
carnitine hexadecenoyltransferase (C16:1Crn, n7), mitochondrial
GENE_ASSOCIATION: NM_002035.1 GENE_LIST: NM_002035.1 SUBSYSTEM: Sphingolipid Metabolism
carnitine eicosenoyltransferase (C20:1Crn, n9)
GENE_ASSOCIATION: (NM_199229.1 or NM_006916.1) GENE_LIST: NM_006916.1 NM_199229.1 SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: NM_006755.1 GENE_LIST: NM_006755.1 SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: (NM_003748.2 or NM_170726.1) GENE_LIST: NM_003748.2 NM_170726.1 SUBSYSTEM: Arginine and Proline Metabolism
1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
GENE_ASSOCIATION: NM_016368.3 GENE_LIST: NM_016368.3 SUBSYSTEM: Inositol Phosphate Metabolism
hexadecenoyl carnitinetransport (C16:1Crn, n9)
phosphatidylglycerol phosphate phosphatase A, mitochondrial, human adipocyte
carnitine octadecanoyltransferase (C18:0Crn), mitochondria
phosphate peroxisomal transport via proton symport
GENE_ASSOCIATION: NM_016308.1 GENE_LIST: NM_016308.1 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: NM_005891.1 GENE_LIST: NM_005891.1 SUBSYSTEM: Tryptophan metabolism
ribonucleoside-diphosphate reductase (CDP)
dihydroorotate dehydrogenase (mitochondrial)
GENE_ASSOCIATION: NM_001025193.1 GENE_LIST: NM_001025193.1 SUBSYSTEM: Nucleotide Metabolism
ribonucleoside-diphosphate reductase (UDP)
methenyltetrahydrofolate cyclohydrolase, mitochondrial
3-Methyl-2-oxobutanoate dehydrogenase, mitochondrial
Leucine transport, Homo Sapiens mitochondria
S-(hydroxymethyl)glutathione dehydrogenase
GENE_ASSOCIATION: NM_000671.3 GENE_LIST: NM_000671.3 SUBSYSTEM: Tyrosine metabolism
Valine transport, Homo Sapiens passive diffusion
methylenetetrahydrofolate dehydrogenase (NADP)
GENE_ASSOCIATION: NM_003734.2 GENE_LIST: NM_003734.2 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
Aminoacetone:oxygen oxidoreductase(deaminating)(flavin-containing)
ubiquinol-6 cytochrome c reductase, Complex III
Palmitoylcarnitine shuttle (C16:0Crn), mitochondrial
GENE_ASSOCIATION: (NM_005917.2 or NM_001039845.1) GENE_LIST: NM_001039845.1 NM_005917.2 SUBSYSTEM: Citrate Cycle (TCA)
GENE_ASSOCIATION: (NM_004845.3 or NM_005017.2) GENE_LIST: NM_004845.3 NM_005017.2 SUBSYSTEM: Fatty Acid Synthesis
fatty-acid--CoA ligase (docosenoate, C22:1 n-9)
GENE_ASSOCIATION: NM_000317.1 GENE_LIST: NM_000317.1 SUBSYSTEM: Folate Metabolism
nucleoside-diphosphate kinase (ATP:dCDP)
GENE_ASSOCIATION: NM_018677.2 GENE_LIST: NM_018677.2 SUBSYSTEM: Fatty Acid Biosynthesis
hexadecenoyl carnitine transprot (C16:1Crn, n7)
GENE_ASSOCIATION: (NM_182977.1 or NM_012343.2) GENE_LIST: NM_012343.2 NM_182977.1 SUBSYSTEM: NAD Metabolism
malate oxaloacetate shuttle, mitochondrial
Propionyl-CoA carboxylase, mitochondrial
GENE_ASSOCIATION: (NM_000282.2 and NM_000532.2) GENE_LIST: NM_000282.2 NM_000532.2 SUBSYSTEM: Phospholipid Metabolism
GENE_ASSOCIATION: (NM_000819.3 or NM_175085.1) GENE_LIST: NM_000819.3 NM_175085.1 SUBSYSTEM: Nucleotide Metabolism
Myristicoyl-CoA desaturase (n-C14:0CoA -> C14:1CoA, n-5)
GENE_ASSOCIATION: (NM_001037582.1 or NM_024906.1 or NM_005063.4) GENE_LIST: NM_001037582.1 NM_005063.4 NM_024906.1 SUBSYSTEM: Fatty Acid Desaturation
carnitine octadecenoyltransferase (C18:1Crn, n5)
fatty-acid--CoA ligase (eicosadienoate, C20:2 n-6), hepatocyte
GENE_ASSOCIATION: (NM_000408.2 or NM_001083112.1) GENE_LIST: NM_000408.2 NM_001083112.1 SUBSYSTEM: Glycerophospholipid Metabolism
glycerol-3-phosphate dehydrogenase (FAD), mitochondrial
C-14 sterol reductase, endoplasmic reticulum
GENE_ASSOCIATION: NM_003273.1 GENE_LIST: NM_003273.1 SUBSYSTEM: Cholesterol Biosynthesis
carnitine eicosanoyltransferase (C20:0Crn), mitochondria
GENE_ASSOCIATION: (NM_014214.1 or NM_005536.2) GENE_LIST: NM_005536.2 NM_014214.1 SUBSYSTEM: Inositol Phosphate Metabolism
GENE_ASSOCIATION: NM_005896.2 GENE_LIST: NM_005896.2 SUBSYSTEM: Citrate Cycle (TCA)
fatty-acid--CoA ligase (octadecadienoate, C18:3 n-3), hepatocyte
L-lactate reversible transport via proton symport
eicosanoate transport (n-C20:0), cytosol to blood
phosphoribosylaminoimidazolesuccinocarboxamide synthase
nucleoside-diphosphate kinase (ATP:dTDP)
GENE_ASSOCIATION: NM_004901.1 GENE_LIST: NM_004901.1 SUBSYSTEM: Nucleotide Metabolism
docosenoyl carnitine transport (C22:1Crn, n9)
GENE_ASSOCIATION: (NM_031947.2 or NM_014252.2) GENE_LIST: NM_014252.2 NM_031947.2 SUBSYSTEM: Transport, Mitochondrial
GENE_ASSOCIATION: NM_000254.1 GENE_LIST: NM_000254.1 SUBSYSTEM: Methionine Metabolism
alcohol dehydrogenase, forward rxn (ethanol -> acetaldehyde)
GENE_ASSOCIATION: NM_000672.2 GENE_LIST: NM_000672.2 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (NM_033253.2 or NM_001002006.1 or NM_012229.2) GENE_LIST: NM_001002006.1 NM_012229.2 NM_033253.2 SUBSYSTEM: Nucleotide Metabolism
cardiolipin synthase, mitochondrial adipocyte
SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (NM_006745.3 or NM_001017369.1) GENE_LIST: NM_001017369.1 NM_006745.3 SUBSYSTEM: Cholesterol Biosynthesis
carnitine hexadecenoyltransferase (C16:1Crn, n9), mitochondrial
GENE_ASSOCIATION: NM_000019.2 GENE_LIST: NM_000019.2 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
GENE_ASSOCIATION: (NM_001001438.1 or NM_002340.3) GENE_LIST: NM_001001438.1 NM_002340.3 SUBSYSTEM: Cholesterol Metabolism
lanosterol synthase, endoplasmic reticulum
GENE_ASSOCIATION: (NM_019036.1 or NM_001042406.1 or NM_000191.2) GENE_LIST: NM_000191.2 NM_001042406.1 NM_019036.1 SUBSYSTEM: Cholesterol Metabolism
hydroxymethylglutaryl-CoA lyase, mitochondrial
GENE_ASSOCIATION: NM_005957.3 GENE_LIST: NM_005957.3 SUBSYSTEM: Folate Metabolism
methylenetetrahydrofolate reductase (NADPH2)
docosahexaenoyl carnitine transport (C22:6Crn, n3)
GENE_ASSOCIATION: NM_000454.4 GENE_LIST: NM_000454.4 SUBSYSTEM: Other
carnitine octadecatrienoyltransferase (C18:3Crn, n3), mitochondrial
carnitine dodecanoyltransferase (C12:0Crn)
GENE_ASSOCIATION: (NM_000481.2 and NM_000108.3 and NM_004483.3 and NM_000170.1) GENE_LIST: NM_000108.3 NM_000170.1 NM_000481.2 NM_004483.3 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (NM_003849.1 and NM_003850.1) GENE_LIST: NM_003849.1 NM_003850.1 SUBSYSTEM: Citrate Cycle (TCA)
GENE_ASSOCIATION: (NM_058179.2 or NM_021154.3) GENE_LIST: NM_021154.3 NM_058179.2 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
pentadecanoyl carnitine transport (C15:0Crn)
carnitine octadecenoyltransferase (C18:1Crn, n7)
GENE_ASSOCIATION: (NM_213611.1 or NM_005888.2 or NM_002635.2) GENE_LIST: NM_002635.2 NM_005888.2 NM_213611.1 SUBSYSTEM: Transport, Mitochondrial
Cholesterol transport, endoplasmic reticulum
GENE_ASSOCIATION: NM_021129.3 GENE_LIST: NM_021129.3 SUBSYSTEM: Other
GENE_ASSOCIATION: (NM_005956.2 or NM_015440.3) GENE_LIST: NM_005956.2 NM_015440.3 SUBSYSTEM: Vitamins & Cofactor Biosynthesis
formate-tetrahydrofolate ligase, mitochondrial
GENE_ASSOCIATION: NM_003875.2 GENE_LIST: NM_003875.2 SUBSYSTEM: Nucleotide Metabolism
phosphoribosylaminoimidazolecarboxamide formyltransferase
GENE_ASSOCIATION: NM_006579.1 GENE_LIST: NM_006579.1 SUBSYSTEM: Cholesterol Metabolism
L-glutamate 5-semialdehyde dehydratase (spontaneous) mitochondrial
GENE_ASSOCIATION: (NM_001921.2 or NM_001012732.1) GENE_LIST: NM_001012732.1 NM_001921.2 SUBSYSTEM: Nucleotide Metabolism
Phosphatidylserine synthase 1, human adipocyte
GENE_ASSOCIATION: NM_014754.1 GENE_LIST: NM_014754.1 SUBSYSTEM: Phospholipid Metabolism
GENE_ASSOCIATION: NM_001984.1 GENE_LIST: NM_001984.1 SUBSYSTEM: Tyrosine metabolism
alphaketobutyrate dehydrogenase (mitochondrial)
GENE_ASSOCIATION: NM_006319.3 GENE_LIST: NM_006319.3 SUBSYSTEM: Phospholipid Metabolism
phosphatidylinositol synthase, human adipocyte
cardiolipin reversible transport, mitochondria, adipocyte
fatty-acid--CoA ligase (tetradecenoate, C14:1 n-5)
phosphatidate reversible transport, mitochondrial, adipocyte
carnitine tetradecanoyltransferase (C14:0Crn)
carnitine docosapentaenoyltransferase (C22:5Crn, n3)
fatty-acid--CoA ligase (eicosenoate, C20:1 n-11)
GENE_ASSOCIATION: (NM_001037811.2 or NM_004493.2) GENE_LIST: NM_001037811.2 NM_004493.2 SUBSYSTEM: Amino Acid Metabolism
3-hydroxyacyl-CoA dehydrogenase (2-Methylacetoacetyl-CoA), mitochondrial
fatty-acid--CoA ligase (docosapentaenoate, C22:5 n-3)
GENE_ASSOCIATION: NM_001698.1 GENE_LIST: NM_001698.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Degradation
GENE_ASSOCIATION: NM_002080.2 GENE_LIST: NM_002080.2 SUBSYSTEM: Amino Acid Metabolism
carnitine octadecanoyltransferase (C18:0Crn)
carnitine pentadecanoyltransferase (C15:0Crn), mitochondria
GENE_ASSOCIATION: (NM_006721.2 or NM_001123.2) GENE_LIST: NM_001123.2 NM_006721.2 SUBSYSTEM: Nucleotide Metabolism
tetradecanoyl carnitine transport (C14:0Crn)
GENE_ASSOCIATION: NM_000859.1 GENE_LIST: NM_000859.1 SUBSYSTEM: Cholesterol Biosynthesis
GENE_ASSOCIATION: (NM_031432.1 or NM_012474.3) GENE_LIST: NM_012474.3 NM_031432.1 SUBSYSTEM: Pyrimidine Metabolism
GENE_ASSOCIATION: (NM_004925.3 or NM_001170.1) GENE_LIST: NM_001170.1 NM_004925.3 SUBSYSTEM: Transport, Extracellular
glycerol transport in/out via diffusion reversible
GENE_ASSOCIATION: NM_000858.4 GENE_LIST: NM_000858.4 SUBSYSTEM: Nucleotide Metabolism
diacylglycerol pyrophosphate phosphatase, human adipocyte
ornithine carbamoyltransferase, mitochondrial
GENE_ASSOCIATION: NM_000531.3 GENE_LIST: NM_000531.3 SUBSYSTEM: Arginine and Proline Metabolism
stearoyl-CoA desaturase (n-C18:0CoA -> C18:1CoA, n-9), adipocyte
fatty acyl-CoA desaturase (C20:4CoA, n3 -> C20:5CoA, n3)
glucose 6-phosphate dehydrogenase, endoplasmic reticulum
3-hydroxyisobutyrate dehydrogenase, mitochondrial
GENE_ASSOCIATION: NM_152740.2 GENE_LIST: NM_152740.2 SUBSYSTEM: Valine, Leucine, and Isoleucine Degradation
L-leucine transport via diffusion, blood
GENE_ASSOCIATION: (NM_001003794.1 or NM_007283.5) GENE_LIST: NM_001003794.1 NM_007283.5 SUBSYSTEM: Triglycerol Degradation
monoacylglycerol hydrolase, human adipocyte
GENE_ASSOCIATION: (NM_003848.1 and NM_003849.1) GENE_LIST: NM_003848.1 NM_003849.1 SUBSYSTEM: Citrate Cycle (TCA)
carnitine octadecatrienoyltransferase (C18:3Crn, n3)
glucose transport, endoplasmic reticulum
GENE_ASSOCIATION: ((NM_004863.2 and NM_006415.2) or (NM_004863.2 and NM_178324.1)) GENE_LIST: NM_004863.2 NM_006415.2 NM_178324.1 SUBSYSTEM: Sphingolipid Metabolism
Biomass Demand, Human Adipocyte (biosynthetic GAM)