MODEL1110130000
type: SBMLModel
species: 302769
reaction: 303302
species: 303061
species: 302975
reaction: 303550
species: 302883
species: 302691
species: 302438
reaction: 303639
species: 302748
species: 302648
reaction: 303462
species: 302556
species: 302958
reaction: 303729
species: 302674
species: 302984
species: 302705
species: 303023
reaction: 303467
species: 302513
reaction: 303281
reaction: 303791
species: 302421
reaction: 303358
reaction: 303313
reaction: 303715
reaction: 303566
species: 302765
reaction: 303700
species: 302610
species: 302920
reaction: 303801
species: 302485
reaction: 303421
reaction: 303674
reaction: 303097
species: 302644
species: 303040
species: 302954
reaction: 303502
reaction: 303459
species: 302670
species: 302468
reaction: 303783
reaction: 303499
species: 302980
species: 302701
reaction: 303305
reaction: 303471
species: 302539
reaction: 303114
reaction: 303651
species: 302447
reaction: 303570
reaction: 303190
species: 302565
species: 302875
reaction: 303369
reaction: 303083
reaction: 303558
species: 302714
species: 303032
species: 302548
reaction: 303776
species: 303066
reaction: 303274
reaction: 303104
species: 302464
species: 303015
species: 302929
species: 302696
reaction: 303289
reaction: 303694
reaction: 303799
species: 302753
species: 302679
reaction: 303094
reaction: 303314

302769
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Phenylpyruvate_C9H7O3

302405
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

303302
type: Reaction
kinetic law: 703751
product: 703739
reactant: 703726
notes: Abbreviation: R_EX_gly_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : gly <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Glycine exchange

304398
type: LocalParameter
value: 0.0

304397
type: LocalParameter
value: 0.0

304396
type: LocalParameter
value: 999999.0

304395
type: LocalParameter
value: -999999.0

703739
type: SpeciesReference
stoichiometry: 1.0
species: 303026

303026
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Glycine_C2H5NO2

302406
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

703726
type: SpeciesReference
stoichiometry: 1.0
species: 302637

302637
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Glycine_C2H5NO2

303061
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Proline_C5H9NO2

302975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: UDP_C9H11N2O12P2

303550
type: Reaction
fast: false
reactant: 711275
name: nucleoside-diphosphate kinase (ATP:GDP)
kinetic law: 711312
product: 711299
reactant: 711262
reversible: true
notes: Abbreviation: R_NDPK1 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + gdp <==> adp + gtp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions. genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)
product: 711287

711275
type: SpeciesReference
stoichiometry: 1.0
species: 302626

302626
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: GDP_C10H12N5O11P2

304943
type: LocalParameter
value: 0.0

304942
type: LocalParameter
value: 0.0

304941
type: LocalParameter
value: 999999.0

304940
type: LocalParameter
value: -999999.0

711299
type: SpeciesReference
stoichiometry: 1.0
species: 302651

302651
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: GTP_C10H12N5O14P3

711262
type: SpeciesReference
stoichiometry: 1.0
species: 302526

302526
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: ATP_C10H12N5O13P3

711287
type: SpeciesReference
stoichiometry: 1.0
species: 302493

302493
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: ADP_C10H12N5O10P2

302883
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: phosphatidylserine (Blattabacterium Blattella germanica)_C1986H3698N50O500P50

302691
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: potassium_K

302438
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Dehydroquinate_C7H9O6

303639
type: Reaction
kinetic law: 714203
product: 714191
name: Phosphatidic acid synthase
reactant: 714119
reversible: false
reactant: 714131
reactant: 714107
reactant: 714155
product: 714179
fast: false
notes: Abbreviation: R_PASYN_Bge Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : glyc3p + (0.14) hdeACP + (0.04) myrsACP + octeACP + (0.72) palmACP + (0.1) tdeACP --> (2) ACP + (0.02) pa_Bge Confidence Level: 2 JLR genes: LOCUS:BLBBGE_508#ABBREVIATION:plsC#ECNUMBERS:2.3.1.51# LOCUS:BLBBGE_599#ABBREVIATION:plsB#ECNUMBERS:2.3.1.15# proteins: NAME:glycerolphosphate acyltransferase#ABBREVIATION:PlsB# NAME:_1-acyl-glycerol-3-phosphate acyltransferase#ABBREVIATION:PlsC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_508) and (BLBBGE_599)
reactant: 714143
reactant: 714167

305242
type: LocalParameter
value: 0.0

305241
type: LocalParameter
value: 0.0

305240
type: LocalParameter
value: 999999.0

305239
type: LocalParameter
value: 0.0

714191
type: SpeciesReference
stoichiometry: 0.02
species: 302749

302749
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: phosphatidate (Blattabacterium Blattella germanica)_C1836H3398O400P50

714119
type: SpeciesReference
stoichiometry: 0.14
species: 302664

302664
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)_C27H49N2O8PRS

714131
type: SpeciesReference
stoichiometry: 0.04
species: 302712

302712
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Myristoyl-ACP (n-C14:0ACP)_C25H47N2O8PRS

714107
type: SpeciesReference
stoichiometry: 1.0
species: 302641

302641
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Glycerol 3-phosphate_C3H7O6P

714155
type: SpeciesReference
stoichiometry: 0.72
species: 302750

302750
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Palmitoyl-ACP (n-C16:0ACP)_C27H51N2O8PRS

714179
type: SpeciesReference
stoichiometry: 2.0
species: 302487

302487
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: acyl carrier protein_C11H21N2O7PRS

714143
type: SpeciesReference
stoichiometry: 1.0
species: 302740

302740
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)_C29H53N2O8PRS

714167
type: SpeciesReference
stoichiometry: 0.1
species: 302930

302930
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)_C25H45N2O8PRS

302748
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Orotate_C5H3N2O4

302648
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: GMP_C10H12N5O8P

303462
type: Reaction
kinetic law: 708128
notes: Abbreviation: R_IG3PS Synonyms: _0 SUBSYSTEM: Histidine Metabolism Equation: [c] : gln-L + prlp --> aicar + eig3p + glu-L + h Confidence Level: 2 Essential in L-histidine synthesis: No definite EC number assigned: EC 2.4.2.-; HisF cyclase genes: LOCUS:BLBBGE_437#ABBREVIATION:hisH#ECNUMBERS:2.4.2.-# LOCUS:BLBBGE_439#ABBREVIATION:hisF#ECNUMBERS:2.4.2.-# proteins: NAME:Imadazoleglycerol phosphate synthase#ABBREVIATION:HisF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_437 and BLBBGE_439)
product: 708080
name: Imidazole-glycerol-3-phosphate synthase
product: 708092
product: 708116
product: 708104
reversible: false
fast: false
reactant: 708055
reactant: 708068

304747
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value: 0.0

304746
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value: 0.0

304745
type: LocalParameter
value: 999999.0

304744
type: LocalParameter
value: 0.0

708080
type: SpeciesReference
stoichiometry: 1.0
species: 302498

302498
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide_C9H13N4O8P

708092
type: SpeciesReference
stoichiometry: 1.0
species: 302595

302595
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate_C6H9N2O6P

708116
type: SpeciesReference
stoichiometry: 1.0
species: 302659

302659
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: H+_H

708104
type: SpeciesReference
stoichiometry: 1.0
species: 302633

302633
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Glutamate_C5H8NO4

708055
type: SpeciesReference
stoichiometry: 1.0
species: 302628

302628
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Glutamine_C5H10N2O3

708068
type: SpeciesReference
stoichiometry: 1.0
species: 302875

302875
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405

302556
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dCMP_C9H12N3O7P

302958
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405

303729
type: Reaction
reactant: 717889
notes: Abbreviation: R_RNDR3 Synonyms: _0 EC Number: 1.17.4.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : cdp + trdrd --> dcdp + h2o + trdox Confidence Level: 2 genes: LOCUS:BLBBGE_310#ABBREVIATION:nrdA#ECNUMBERS:1.17.4.1# LOCUS:BLBBGE_p006#ABBREVIATION:nrdF#ECNUMBERS:1.17.4.1# proteins: NAME:ribonucleoside-diphosphate reductase subunit alpha#ABBREVIATION:NrdA# NAME:ribonucleotide-diphosphate reductase beta subunit#ABBREVIATION:NrdF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_310 and BLBBGE_p006)
name: ribonucleoside-diphosphate reductase (CDP)
reactant: 717877
product: 717901
fast: false
reversible: false
kinetic law: 717937
product: 717925
product: 717913

717889
type: SpeciesReference
stoichiometry: 1.0
species: 302949

302949
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Reduced thioredoxin_XH2

717877
type: SpeciesReference
stoichiometry: 1.0
species: 302528

302528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: CDP_C9H12N3O11P2

717901
type: SpeciesReference
stoichiometry: 1.0
species: 302555

302555
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dCDP_C9H12N3O10P2

305523
type: LocalParameter
value: 0.0

305521
type: LocalParameter
value: 0.0

305520
type: LocalParameter
value: 999999.0

305518
type: LocalParameter
value: 0.0

717925
type: SpeciesReference
stoichiometry: 1.0
species: 302948

302948
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Oxidized thioredoxin_X

717913
type: SpeciesReference
stoichiometry: 1.0
species: 302655

302655
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: H2O_H2O

302674
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Hypoxanthine_C5H4N4O

302984
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Uracil_C4H4N2O2

302705
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5,10-Methenyltetrahydrofolate_C20H20N7O6

303023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Fumarate_C4H2O4

303467
type: Reaction
fast: false
name: L-isoleucine transport via ABC system
reactant: 708287
reactant: 708275
product: 708323
product: 708299
notes: Abbreviation: R_ILEabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + ile-L[e] --> adp[c] + h[c] + ile-L[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
kinetic law: 708347
product: 708335
reactant: 708262
reversible: false
product: 708311

708287
type: SpeciesReference
stoichiometry: 1.0
species: 302680

302680
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Isoleucine_C6H13NO2

708275
type: SpeciesReference
stoichiometry: 1.0
species: 302655

708323
type: SpeciesReference
stoichiometry: 1.0
species: 302679

302679
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Isoleucine_C6H13NO2

708299
type: SpeciesReference
stoichiometry: 1.0
species: 302493

304759
type: LocalParameter
value: 0.0

304758
type: LocalParameter
value: 0.0

304757
type: LocalParameter
value: 999999.0

304756
type: LocalParameter
value: 0.0

708335
type: SpeciesReference
stoichiometry: 1.0
species: 302853

302853
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Phosphate_HO4P

708262
type: SpeciesReference
stoichiometry: 1.0
species: 302526

708311
type: SpeciesReference
stoichiometry: 1.0
species: 302659

302513
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: apoprotein [acyl carrier protein]_RHO

303281
type: Reaction
kinetic law: 703351
product: 703339
reactant: 703327
notes: Abbreviation: R_EX_asn_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : asn-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Asparagine exchange

304348
type: LocalParameter
value: 0.0

304347
type: LocalParameter
value: 0.0

304346
type: LocalParameter
value: 999999.0

304345
type: LocalParameter
value: -999999.0

703339
type: SpeciesReference
stoichiometry: 1.0
species: 303009

303009
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Asparagine_C4H8N2O3

703327
type: SpeciesReference
stoichiometry: 1.0
species: 302521

302521
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Asparagine_C4H8N2O3

303791
type: Reaction
product: 721269
product: 721294
notes: Abbreviation: R_UAMAGS Synonyms: _0 EC Number: 6.3.2.9 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : atp + glu-D + uama --> adp + h + pi + uamag Confidence Level: 2 genes: LOCUS:BLBBGE_388#ABBREVIATION:murD#ECNUMBERS:6.3.2.9# proteins: NAME:UDP-N-acetylmuramoylalanine-D-glutamate ligase#ABBREVIATION:MurD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_388)
reversible: false
product: 721307
reactant: 721257
reactant: 721233
fast: false
product: 721282
kinetic law: 721319
name: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
reactant: 721245

721269
type: SpeciesReference
stoichiometry: 1.0
species: 302493

721294
type: SpeciesReference
stoichiometry: 1.0
species: 302853

721307
type: SpeciesReference
stoichiometry: 1.0
species: 302969

302969
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405

721257
type: SpeciesReference
stoichiometry: 1.0
species: 302968

302968
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405

721233
type: SpeciesReference
stoichiometry: 1.0
species: 302526

721282
type: SpeciesReference
stoichiometry: 1.0
species: 302659

305761
type: LocalParameter
value: 0.0

305760
type: LocalParameter
value: 0.0

305759
type: LocalParameter
value: 999999.0

305758
type: LocalParameter
value: 0.0

721245
type: SpeciesReference
stoichiometry: 1.0
species: 302632

302632
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Glutamate_C5H8NO4

302421
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate_C7H10O10P

303358
type: Reaction
kinetic law: 704780
product: 704768
reactant: 704756
notes: Abbreviation: R_EX_trp_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : trp-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Tryptophan exchange

304524
type: LocalParameter
value: 0.0

304523
type: LocalParameter
value: 0.0

304522
type: LocalParameter
value: 999999.0

304521
type: LocalParameter
value: 0.0

704768
type: SpeciesReference
stoichiometry: 1.0
species: 303072

303072
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Tryptophan_C11H12N2O2

704756
type: SpeciesReference
stoichiometry: 1.0
species: 302953

302953
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Tryptophan_C11H12N2O2

303313
type: Reaction
kinetic law: 703934
product: 703922
reactant: 703910
notes: Abbreviation: R_EX_h_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : h <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: H+ exchange

304422
type: LocalParameter
value: 0.0

304421
type: LocalParameter
value: 0.0

304420
type: LocalParameter
value: 999999.0

304418
type: LocalParameter
value: -999999.0

703922
type: SpeciesReference
stoichiometry: 1.0
species: 303035

303035
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: H+_H

703910
type: SpeciesReference
stoichiometry: 1.0
species: 302660

302660
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: H+_H

303715
type: Reaction
product: 717176
product: 717164
name: purine-nucleoside phosphorylase (Deoxyinosine)
kinetic law: 717188
reversible: true
reactant: 717152
fast: false
reactant: 717140
notes: Abbreviation: R_PUNP6 Synonyms: _0 EC Number: 2.4.2.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : din + pi <==> 2dr1p + hxan Confidence Level: 2 Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase genes: LOCUS:BLBBGE_377#ABBREVIATION:pndA#ECNUMBERS:2.4.2.1# proteins: NAME:purine-nucleoside phosphorylase#ABBREVIATION:PndA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)

717176
type: SpeciesReference
stoichiometry: 1.0
species: 302674

717164
type: SpeciesReference
stoichiometry: 1.0
species: 302425

302425
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Deoxy-D-ribose 1-phosphate_C5H9O7P

305467
type: LocalParameter
value: 0.0

305466
type: LocalParameter
value: 0.0

305465
type: LocalParameter
value: 999999.0

305464
type: LocalParameter
value: -999999.0

717152
type: SpeciesReference
stoichiometry: 1.0
species: 302853

717140
type: SpeciesReference
stoichiometry: 1.0
species: 302576

302576
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Deoxyinosine_C10H12N4O4

303566
type: Reaction
fast: false
reactant: 711759
reactant: 711747
notes: Abbreviation: R_NDPK9 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + idp <==> adp + itp Confidence Level: 2 NCD genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Sabree, Z.L., Kambhampati, S., Moran, N.A.#TITLE:Nitrogen recycling and nutritional provisioning by Blattabacterium, the cockroach endosymbiont.#JOURNAL:Proc Natl Acad Sci U S A.#YEAR:2009#PUBMED: 19880743# GENE ASSOCIATION: (BLBBGE_453)
product: 711783
kinetic law: 711795
name: nucleoside-diphosphate kinase (ATP:IDP)
product: 711771
reversible: true

711759
type: SpeciesReference
stoichiometry: 1.0
species: 302678

302678
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: IDP_C10H11N4O11P2

711747
type: SpeciesReference
stoichiometry: 1.0
species: 302526

711783
type: SpeciesReference
stoichiometry: 1.0
species: 302688

302688
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: ITP_C10H11N4O14P3

304979
type: LocalParameter
value: 0.0

304978
type: LocalParameter
value: 0.0

304977
type: LocalParameter
value: 999999.0

304976
type: LocalParameter
value: -999999.0

711771
type: SpeciesReference
stoichiometry: 1.0
species: 302493

302765
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Phenylalanine_C9H11NO2

303700
type: Reaction
reactant: 716381
notes: Abbreviation: R_PRPPS Synonyms: _0 EC Number: 2.7.6.1 SUBSYSTEM: Histidine Metabolism Equation: [c] : atp + r5p --> amp + h + prpp Confidence Level: 2 genes: LOCUS:BLBBGE_497#ABBREVIATION:prsA#ECNUMBERS:2.7.6.1# proteins: NAME:phosphoribosylpyrophosphate synthetase#ABBREVIATION:PrsA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_497)
reactant: 716393
product: 716417
product: 716429
product: 716405
reversible: false
kinetic law: 716441
fast: false
name: phosphoribosylpyrophosphate synthetase

716381
type: SpeciesReference
stoichiometry: 1.0
species: 302526

716393
type: SpeciesReference
stoichiometry: 1.0
species: 302898

302898
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: alpha-D-Ribose 5-phosphate_C5H9O8P

716417
type: SpeciesReference
stoichiometry: 1.0
species: 302659

716429
type: SpeciesReference
stoichiometry: 1.0
species: 302880

302880
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Phospho-alpha-D-ribose 1-diphosphate_C5H8O14P3

716405
type: SpeciesReference
stoichiometry: 1.0
species: 302511

302511
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: AMP_C10H12N5O7P

305407
type: LocalParameter
value: 0.0

305406
type: LocalParameter
value: 0.0

305405
type: LocalParameter
value: 999999.0

305404
type: LocalParameter
value: 0.0

302610
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine_C8H15N3O8P

302920
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Succinate semialdehyde-thiamin diphosphate anion_C16H21N4O10P2S

303801
type: Reaction
kinetic law: 721889
product: 721877
product: 721865
reactant: 721853
notes: Abbreviation: R_UPP3S Synonyms: _0 EC Number: 4.2.1.75 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : hmbil --> h2o + uppg3 Confidence Level: 2 genes: LOCUS:BLBBGE_290#ABBREVIATION:hemD#ECNUMBERS:4.2.1.75# LOCUS:BLBBGE_576#ABBREVIATION:hemD#ECNUMBERS:4.2.1.75# proteins: NAME:Uroporphyrinogen III synthase#ABBREVIATION:HemD# NAME:Uroporphyrinogen III synthase#ABBREVIATION:HemD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_290) or (BLBBGE_576)
fast: false
reversible: false
name: uroporphyrinogen-III synthase

305801
type: LocalParameter
value: 0.0

305800
type: LocalParameter
value: 0.0

305799
type: LocalParameter
value: 999999.0

305798
type: LocalParameter
value: 0.0

721877
type: SpeciesReference
stoichiometry: 1.0
species: 302983

302983
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Uroporphyrinogen III_C40H36N4O16

721865
type: SpeciesReference
stoichiometry: 1.0
species: 302655

721853
type: SpeciesReference
stoichiometry: 1.0
species: 302671

302671
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Hydroxymethylbilane_C40H38N4O17

302485
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N2-Acetyl-L-ornithine_C7H14N2O3

303421
type: Reaction
kinetic law: 706691
product: 706679
reactant: 706667
notes: Abbreviation: R_GLYCt Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: glyc[c] <==> glyc[e] Confidence Level: 2 NCD genes: LOCUS:BLBBGE_460#ABBREVIATION:glpF# proteins: NAME:MIP channel, glycerol diffusion#ABBREVIATION:GlpF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_460)
fast: false
reversible: true
name: glycerol transport via channel

304657
type: LocalParameter
value: 0.0

304656
type: LocalParameter
value: 0.0

304655
type: LocalParameter
value: 999999.0

304654
type: LocalParameter
value: -999999.0

706679
type: SpeciesReference
stoichiometry: 1.0
species: 302644

302644
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Glycerol_C3H8O3

706667
type: SpeciesReference
stoichiometry: 1.0
species: 302642

302642
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Glycerol_C3H8O3

303674
type: Reaction
kinetic law: 715273
product: 715261
reactant: 715249
notes: Abbreviation: R_PPBNGt Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: ppbng[e] <==> ppbng[c] Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Phorphobilinogen transport

305333
type: LocalParameter
value: 0.0

305331
type: LocalParameter
value: 0.0

305329
type: LocalParameter
value: 999999.0

305328
type: LocalParameter
value: -999999.0

715261
type: SpeciesReference
stoichiometry: 1.0
species: 302860

302860
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Porphobilinogen_C10H13N2O4

715249
type: SpeciesReference
stoichiometry: 1.0
species: 302863

302863
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Porphobilinogen_C10H13N2O4

303097
type: Reaction
reversible: false
fast: false
reactant: 695591
reactant: 695615
name: adenine deaminase
reactant: 695603
notes: Abbreviation: R_ADD Synonyms: _0 EC Number: 3.5.4.2 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : ade + h + h2o --> hxan + nh4 Confidence Level: 1 note: reaction also occures spontaneously - oxidative deaminination (MKA) genes: none proteins: none citations: none GENE ASSOCIATION:
product: 695627
kinetic law: 695651
product: 695639

695591
type: SpeciesReference
stoichiometry: 1.0
species: 302490

302490
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Adenine_C5H5N5

695615
type: SpeciesReference
stoichiometry: 1.0
species: 302655

695603
type: SpeciesReference
stoichiometry: 1.0
species: 302659

695627
type: SpeciesReference
stoichiometry: 1.0
species: 302674

303872
type: LocalParameter
value: 0.0

303871
type: LocalParameter
value: 0.0

303870
type: LocalParameter
value: 999999.0

303869
type: LocalParameter
value: 0.0

695639
type: SpeciesReference
stoichiometry: 1.0
species: 302725

302725
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Ammonium_H4N

303040
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: potassium_K

302954
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Tyrosine_C9H11NO3

303502
type: Reaction
reactant: 709509
reactant: 709497
product: 709521
notes: Abbreviation: R_LEUTA Synonyms: _2 EC Number: 2.6.1.42 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 4mop + glu-L <==> akg + leu-L Confidence Level: 2 genes: LOCUS:BLBBGE_455#ABBREVIATION:ilvE#ECNUMBERS:2.6.1.42,-!-,2.6.1.2# LOCUS:BLBBGE_342#ABBREVIATION:tyrB#ECNUMBERS:2.6.1.57# proteins: NAME:Branched-chain-amino-acid aminotransferase#ABBREVIATION:IlvE# NAME:Tyrosine aminotransferase#ABBREVIATION:TyrB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_342) or (BLBBGE_455)
reversible: true
fast: false
kinetic law: 709545
name: leucine transaminase
product: 709533

709509
type: SpeciesReference
stoichiometry: 1.0
species: 302633

709497
type: SpeciesReference
stoichiometry: 1.0
species: 302454

302454
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _4-Methyl-2-oxopentanoate_C6H9O3

709521
type: SpeciesReference
stoichiometry: 1.0
species: 302500

302500
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Oxoglutarate_C5H4O5

304835
type: LocalParameter
value: 0.0

304834
type: LocalParameter
value: 0.0

304833
type: LocalParameter
value: 999999.0

304832
type: LocalParameter
value: -999999.0

709533
type: SpeciesReference
stoichiometry: 1.0
species: 302692

302692
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Leucine_C6H13NO2

303459
type: Reaction
kinetic law: 708043
product: 708031
reactant: 708018
notes: Abbreviation: R_ICHORSi Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : chor --> ichor Confidence Level: 2 JLR- added irreversible form of ICHORS genes: LOCUS:BLBBGE_192#ABBREVIATION:menF#ECNUMBERS:5.4.4.2# proteins: NAME:isochorismate synthase II#ABBREVIATION:EntC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_192)
fast: false
reversible: false
name: Isochorismate Synthase

304743
type: LocalParameter
value: 0.0

304742
type: LocalParameter
value: 0.0

304741
type: LocalParameter
value: 999999.0

304739
type: LocalParameter
value: 0.0

708031
type: SpeciesReference
stoichiometry: 1.0
species: 302675

302675
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Isochorismate_C10H8O6

708018
type: SpeciesReference
stoichiometry: 1.0
species: 302531

302531
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: chorismate_C10H8O6

302670
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Histidinol_C6H12N3O

302468
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-enolpyruvoyl-6-hydroxy-2-succinyl-3-cyclohexene-1-carboxylate_C14H14O9

303783
type: Reaction
reversible: true
reactant: 720823
product: 720835
name: tyrosine transaminase
notes: Abbreviation: R_TYRTA Synonyms: _13 EC Number: 2.6.1.5 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : akg + tyr-L <==> 34hpp + glu-L Confidence Level: 2 genes: LOCUS:BLBBGE_355#ABBREVIATION:aspC#ECNUMBERS:2.6.1.1# LOCUS:BLBBGE_342#ABBREVIATION:tyrB#ECNUMBERS:2.6.1.57# proteins: NAME:Tyrosine aminotransferase#ABBREVIATION:TyrB# NAME:aspartate aminotransferase#ABBREVIATION:AspC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_342) or (BLBBGE_355)
kinetic law: 720859
product: 720847
fast: false
reactant: 720811

720823
type: SpeciesReference
stoichiometry: 1.0
species: 302954

720835
type: SpeciesReference
stoichiometry: 1.0
species: 302433

302433
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-(4-Hydroxyphenyl)pyruvate_C9H7O4

305734
type: LocalParameter
value: 0.0

305733
type: LocalParameter
value: 0.0

305732
type: LocalParameter
value: 999999.0

305731
type: LocalParameter
value: -999999.0

720847
type: SpeciesReference
stoichiometry: 1.0
species: 302633

720811
type: SpeciesReference
stoichiometry: 1.0
species: 302500

303499
type: Reaction
product: 709436
fast: false
notes: Abbreviation: R_LEUabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + leu-L[e] --> adp[c] + h[c] + leu-L[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 709460
kinetic law: 709485
name: L-leucine transport via ABC system
reactant: 709412
reactant: 709400
product: 709448
reactant: 709424
product: 709473
reversible: false

709436
type: SpeciesReference
stoichiometry: 1.0
species: 302493

709460
type: SpeciesReference
stoichiometry: 1.0
species: 302692

304831
type: LocalParameter
value: 0.0

304830
type: LocalParameter
value: 0.0

304829
type: LocalParameter
value: 999999.0

304828
type: LocalParameter
value: 0.0

709412
type: SpeciesReference
stoichiometry: 1.0
species: 302655

709400
type: SpeciesReference
stoichiometry: 1.0
species: 302526

709448
type: SpeciesReference
stoichiometry: 1.0
species: 302659

709424
type: SpeciesReference
stoichiometry: 1.0
species: 302693

302693
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Leucine_C6H13NO2

709473
type: SpeciesReference
stoichiometry: 1.0
species: 302853

302980
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: UMP_C9H11N2O9P

302701
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Malonyl-CoA_C24H33N7O19P3S

303305
type: Reaction
kinetic law: 703788
product: 703775
reactant: 703763
notes: Abbreviation: R_EX_glyald_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : glyald <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: D-Glyceraldehyde exchange

304402
type: LocalParameter
value: 0.0

304401
type: LocalParameter
value: 0.0

304400
type: LocalParameter
value: 999999.0

304399
type: LocalParameter
value: 0.0

703775
type: SpeciesReference
stoichiometry: 1.0
species: 303029

303029
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: D-Glyceraldehyde_C3H6O3

703763
type: SpeciesReference
stoichiometry: 1.0
species: 302640

302640
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: D-Glyceraldehyde_C3H6O3

303471
type: Reaction
kinetic law: 708456
product: 708444
product: 708431
reactant: 708419
notes: Abbreviation: R_IMPC Synonyms: _0 EC Number: 3.5.4.10 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : fprica --> h2o + imp Confidence Level: 2 genes: LOCUS:BLBBGE_480#ABBREVIATION:purH#ECNUMBERS:3.5.4.10,-!-,2.1.2.3# proteins: NAME:AICAR transformylase and IMP cyclohydrolase#ABBREVIATION:PurH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_480)
fast: false
reversible: false
name: IMP cyclohydrolase

304769
type: LocalParameter
value: 0.0

304768
type: LocalParameter
value: 0.0

304767
type: LocalParameter
value: 999999.0

304765
type: LocalParameter
value: 0.0

708444
type: SpeciesReference
stoichiometry: 1.0
species: 302683

302683
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: IMP_C10H11N4O8P

708431
type: SpeciesReference
stoichiometry: 1.0
species: 302655

708419
type: SpeciesReference
stoichiometry: 1.0
species: 302612

302612
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide_C10H13N4O9P

302539
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Cytosine_C4H5N3O

303114
type: Reaction
kinetic law: 696336
fast: false
reactant: 696288
notes: Abbreviation: R_AGMT Synonyms: _0 EC Number: 3.5.3.11 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : agm + h2o --> ptrc + urea Confidence Level: 2 genes: LOCUS:BLBBGE_059#ABBREVIATION:speB#ECNUMBERS:3.5.3.11# proteins: NAME:agmatinase#ABBREVIATION:SpeB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_059)
product: 696324
name: agmatinase
reversible: false
product: 696312
reactant: 696300

303924
type: LocalParameter
value: 0.0

303923
type: LocalParameter
value: 0.0

303922
type: LocalParameter
value: 999999.0

303921
type: LocalParameter
value: 0.0

696288
type: SpeciesReference
stoichiometry: 1.0
species: 302494

302494
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Agmatine_C5H16N4

696324
type: SpeciesReference
stoichiometry: 1.0
species: 302985

302985
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Urea_CH4N2O

696312
type: SpeciesReference
stoichiometry: 1.0
species: 302885

302885
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Putrescine_C4H14N2

696300
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303651
type: Reaction
product: 714613
product: 714625
name: phosphoglycerate dehydrogenase
reversible: true
reactant: 714601
product: 714637
kinetic law: 714649
reactant: 714589
fast: false
notes: Abbreviation: R_PGCD Synonyms: _0 EC Number: 1.1.1.95 SUBSYSTEM: Glycine and Serine Metabolism Equation: [c] : 3pg + nad <==> 3php + h + nadh Confidence Level: 2 genes: LOCUS:BLBBGE_283#ABBREVIATION:serA#ECNUMBERS:1.1.1.95# proteins: NAME:Phosphoglycerate dehydrogenase#ABBREVIATION:SerA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_283)

714613
type: SpeciesReference
stoichiometry: 1.0
species: 302447

302447
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Phosphohydroxypyruvate_C3H2O7P

714625
type: SpeciesReference
stoichiometry: 1.0
species: 302659

714601
type: SpeciesReference
stoichiometry: 1.0
species: 302719

302719
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

714637
type: SpeciesReference
stoichiometry: 1.0
species: 302720

302720
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

305275
type: LocalParameter
value: 0.0

305273
type: LocalParameter
value: 0.0

305272
type: LocalParameter
value: 999999.0

305270
type: LocalParameter
value: -999999.0

714589
type: SpeciesReference
stoichiometry: 1.0
species: 302446

302446
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Phospho-D-glycerate_C3H4O7P

303570
type: Reaction
reactant: 711855
reactant: 711843
notes: Abbreviation: R_NMNAT Synonyms: _0 EC Number: 2.7.7.1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + h + nmn --> nad + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_327#ABBREVIATION:nadD#ECNUMBERS:2.7.7.18# proteins: NAME:Nicotinic acid mononucleotide adenyltransferase#ABBREVIATION:NadD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_327)
fast: false
reversible: false
product: 711891
product: 711879
kinetic law: 711903
name: nicotinamide-nucleotide adenylyltransferase
reactant: 711867

711855
type: SpeciesReference
stoichiometry: 1.0
species: 302659

711843
type: SpeciesReference
stoichiometry: 1.0
species: 302526

711891
type: SpeciesReference
stoichiometry: 1.0
species: 302865

302865
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Diphosphate_HO7P2

711879
type: SpeciesReference
stoichiometry: 1.0
species: 302719

304987
type: LocalParameter
value: 0.0

304986
type: LocalParameter
value: 0.0

304985
type: LocalParameter
value: 999999.0

304984
type: LocalParameter
value: 0.0

711867
type: SpeciesReference
stoichiometry: 1.0
species: 302730

302730
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: NMN_C11H14N2O8P

303190
type: Reaction
fast: false
reactant: 700163
notes: Abbreviation: R_CTPS2 Synonyms: _0 EC Number: 6.3.4.2 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : atp + gln-L + h2o + utp --> adp + ctp + glu-L + (2) h + pi Confidence Level: 2 genes: LOCUS:BLBBGE_219#ABBREVIATION:pyrG#ECNUMBERS:6.3.4.2# proteins: NAME:CTP synthetase#ABBREVIATION:PyrG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_219)
reactant: 700175
product: 700199
product: 700187
product: 700235
reversible: false
kinetic law: 700247
product: 700223
name: CTP synthase (glutamine)
product: 700211
reactant: 700151
reactant: 700139

700163
type: SpeciesReference
stoichiometry: 1.0
species: 302655

700175
type: SpeciesReference
stoichiometry: 1.0
species: 302990

302990
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: UTP_C9H11N2O15P3

700199
type: SpeciesReference
stoichiometry: 1.0
species: 302541

302541
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: CTP_C9H12N3O14P3

700187
type: SpeciesReference
stoichiometry: 1.0
species: 302493

700235
type: SpeciesReference
stoichiometry: 1.0
species: 302853

304130
type: LocalParameter
value: 0.0

304129
type: LocalParameter
value: 0.0

304128
type: LocalParameter
value: 999999.0

304126
type: LocalParameter
value: 0.0

700223
type: SpeciesReference
stoichiometry: 2.0
species: 302659

700211
type: SpeciesReference
stoichiometry: 1.0
species: 302633

700151
type: SpeciesReference
stoichiometry: 1.0
species: 302628

700139
type: SpeciesReference
stoichiometry: 1.0
species: 302526

302565
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dGTP_C10H12N5O13P3

303369
type: Reaction
kinetic law: 704985
product: 704973
product: 704961
reactant: 704949
notes: Abbreviation: R_FBAb Synonyms: _0 EC Number: 4.1.2.13 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : f1p <==> dhap + glyald Confidence Level: 2 genes: LOCUS:BLBBGE_476#ABBREVIATION:fbaA#ECNUMBERS:4.1.2.13# proteins: NAME:fructose-bisphosphate aldolase II#ABBREVIATION:FbaA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_476)
fast: false
reversible: true
name: fructose-bisphosphate aldolaseB

304546
type: LocalParameter
value: 0.0

304545
type: LocalParameter
value: 0.0

304544
type: LocalParameter
value: 999999.0

304543
type: LocalParameter
value: -999999.0

704973
type: SpeciesReference
stoichiometry: 1.0
species: 302638

302638
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Glyceraldehyde_C3H6O3

704961
type: SpeciesReference
stoichiometry: 1.0
species: 302566

302566
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Dihydroxyacetone phosphate_C3H5O6P

704949
type: SpeciesReference
stoichiometry: 1.0
species: 302596

302596
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Fructose 1-phosphate_C6H11O9P

303083
type: Reaction
name: acetolactate synthase
product: 695142
notes: Abbreviation: R_ACLS Synonyms: _0 EC Number: 4.1.3.18 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : h + (2) pyr --> alac-S + co2 Confidence Level: 2 A flavoprotein. Requires thiamine diphosphate; also catalyses the formation of 2-aceto-2-hydroxybutanoate (see ACHBS) Also EC 2.2.1.6 - NCD genes: LOCUS:BLBBGE_556#ABBREVIATION:ilvI#ECNUMBERS:2.2.1.6# LOCUS:BLBBGE_555#ABBREVIATION:ilvH#ECNUMBERS:2.2.1.6# proteins: NAME:acetolactate synthase III#ABBREVIATION:IlvHI# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_555 and BLBBGE_556)
product: 695130
reversible: false
fast: false
reactant: 695117
kinetic law: 695154
reactant: 695104

695142
type: SpeciesReference
stoichiometry: 1.0
species: 302536

302536
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: CO2_CO2

695130
type: SpeciesReference
stoichiometry: 1.0
species: 302508

302508
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (S)-2-Acetolactate_C5H7O4

695117
type: SpeciesReference
stoichiometry: 2.0
species: 302893

302893
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Pyruvate_C3H3O3

303836
type: LocalParameter
value: 0.0

303835
type: LocalParameter
value: 0.0

303834
type: LocalParameter
value: 999999.0

303833
type: LocalParameter
value: 0.0

695104
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303558
type: Reaction
notes: Abbreviation: R_NDPK5 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dgdp <==> adp + dgtp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions. genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)
product: 711542
kinetic law: 711554
product: 711530
reactant: 711518
name: nucleoside-diphosphate kinase (ATP:dGDP)
reversible: true
reactant: 711505
fast: false

711542
type: SpeciesReference
stoichiometry: 1.0
species: 302565

304961
type: LocalParameter
value: 0.0

304960
type: LocalParameter
value: 0.0

304959
type: LocalParameter
value: 999999.0

304958
type: LocalParameter
value: -999999.0

711530
type: SpeciesReference
stoichiometry: 1.0
species: 302493

711518
type: SpeciesReference
stoichiometry: 1.0
species: 302561

302561
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dGDP_C10H12N5O10P2

711505
type: SpeciesReference
stoichiometry: 1.0
species: 302526

302714
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Sodium_Na

303032
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: H2O_H2O

302548
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dADP_C10H12N5O9P2

303776
type: Reaction
name: triokinase
reversible: false
product: 720451
reactant: 720427
product: 720475
notes: Abbreviation: R_TRIOK Synonyms: _0 EC Number: 2.7.1.28 SUBSYSTEM: Fructose and Mannose Metabolism Equation: [c] : atp + glyald --> adp + g3p + h Confidence Level: 2 genes: LOCUS:BLBBGE_459#ABBREVIATION:glpK#ECNUMBERS:2.7.1.28,-!-,2.7.1.30# proteins: NAME:glycerol kinase#ABBREVIATION:GlpK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_459)
kinetic law: 720487
reactant: 720439
product: 720463
fast: false

720451
type: SpeciesReference
stoichiometry: 1.0
species: 302493

720427
type: SpeciesReference
stoichiometry: 1.0
species: 302526

720475
type: SpeciesReference
stoichiometry: 1.0
species: 302659

305707
type: LocalParameter
value: 0.0

305706
type: LocalParameter
value: 0.0

305705
type: LocalParameter
value: 999999.0

305704
type: LocalParameter
value: 0.0

720439
type: SpeciesReference
stoichiometry: 1.0
species: 302638

720463
type: SpeciesReference
stoichiometry: 1.0
species: 302620

302620
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Glyceraldehyde 3-phosphate_C3H5O6P

303066
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Sulfate_O4S

303274
type: Reaction
kinetic law: 703243
product: 703231
reactant: 703219
notes: Abbreviation: R_EX_akg_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : akg <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: _2-Oxoglutarate exchange

304336
type: LocalParameter
value: 0.0

304335
type: LocalParameter
value: 0.0

304334
type: LocalParameter
value: 0.0

304332
type: LocalParameter
value: 0.0

703231
type: SpeciesReference
stoichiometry: 1.0
species: 303004

303004
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: _2-Oxoglutarate_C5H4O5

703219
type: SpeciesReference
stoichiometry: 1.0
species: 302502

302502
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: _2-Oxoglutarate_C5H4O5

303104
type: Reaction
reactant: 695903
product: 695915
reversible: true
name: adentylate kinase (ITP)
reactant: 695891
kinetic law: 695939
product: 695927
fast: false
notes: Abbreviation: R_ADK4 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : amp + itp <==> adp + idp Confidence Level: 2 JLR genes: LOCUS:BLBBGE_215#ABBREVIATION:adk#ECNUMBERS:2.7.4.3# proteins: NAME:Adenylate kinase#ABBREVIATION:Adk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_215)

695903
type: SpeciesReference
stoichiometry: 1.0
species: 302688

695915
type: SpeciesReference
stoichiometry: 1.0
species: 302493

695891
type: SpeciesReference
stoichiometry: 1.0
species: 302511

303896
type: LocalParameter
value: 0.0

303895
type: LocalParameter
value: 0.0

303894
type: LocalParameter
value: 999999.0

303892
type: LocalParameter
value: -999999.0

695927
type: SpeciesReference
stoichiometry: 1.0
species: 302678

302464
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Amino-6-(5'-phosphoribosylamino)uracil_C9H13N4O9P

303015
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: (S)-Dihydroorotate_C5H5N2O4

302929
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: O-Succinyl-L-homoserine_C8H12NO6

302696
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Lysine_C6H15N2O2

303289
type: Reaction
kinetic law: 703497
product: 703485
reactant: 703473
notes: Abbreviation: R_EX_dhor_S_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : dhor-S <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: S-Dihydroorotate

304366
type: LocalParameter
value: 0.0

304365
type: LocalParameter
value: 0.0

304364
type: LocalParameter
value: 999999.0

304363
type: LocalParameter
value: -999999.0

703485
type: SpeciesReference
stoichiometry: 1.0
species: 303015

703473
type: SpeciesReference
stoichiometry: 1.0
species: 302572

302572
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: (S)-Dihydroorotate_C5H5N2O4

303694
type: Reaction
product: 716032
fast: false
name: phosphoribosylaminoimidazolesuccinocarboxamide synthase
product: 716044
reactant: 716008
notes: Abbreviation: R_PRASCS Synonyms: _0 EC Number: 6.3.2.6 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : 5aizc + asp-L + atp --> 25aics + adp + h + pi Confidence Level: 2 genes: LOCUS:BLBBGE_484#ABBREVIATION:purC#ECNUMBERS:6.3.2.6# proteins: NAME:phosphoribosyaminoimidazole-succinocarboxamide synthetase#ABBREVIATION:PurC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_484)
reactant: 715996
reversible: false
reactant: 716020
product: 716056
product: 716068
kinetic law: 716080

716032
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species: 302413

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initial concentration: NaN
initial amount: NaN
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name: (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate_C13H15N4O12P

716044
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stoichiometry: 1.0
species: 302493

716008
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stoichiometry: 1.0
species: 302522

302522
type: Species
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initial concentration: NaN
initial amount: NaN
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name: L-Aspartate_C4H6NO4

715996
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species: 302461

302461
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constant: false
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initial concentration: NaN
initial amount: NaN
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name: _5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate_C9H11N3O9P

716020
type: SpeciesReference
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species: 302526

716056
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species: 302659

716068
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stoichiometry: 1.0
species: 302853

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305382
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305381
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305379
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value: 0.0

303799
type: Reaction
kinetic law: 721841
reactant: 721803
product: 721829
product: 721816
name: UMP kinase
reactant: 721791
fast: false
notes: Abbreviation: R_UMPK Synonyms: _9 EC Number: 2.7.4.14 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + ump <==> adp + udp Confidence Level: 2 genes: LOCUS:BLBBGE_120#ABBREVIATION:pyrH#ECNUMBERS:2.7.4.-# LOCUS:BLBBGE_058#ABBREVIATION:cmk#ECNUMBERS:2.7.4.14# proteins: NAME:cytidine monophosphate kinase#ABBREVIATION:Cmk# NAME:uridylate kinase#ABBREVIATION:PyrH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_120) or (BLBBGE_058)
reversible: true

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305793
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value: 999999.0

305791
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721803
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species: 302980

721829
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721816
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species: 302493

721791
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species: 302526

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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: Pantetheine 4'-phosphate_C11H21N2O7PS

303094
type: Reaction
fast: false
name: Adenosine deaminase
reactant: 695519
notes: Abbreviation: R_ADA Synonyms: _0 EC Number: 3.5.4.4 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : adn + h + h2o --> ins + nh4 Confidence Level: 1 Added EC- JLR genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 695531
product: 695555
product: 695567
reversible: false
kinetic law: 695579
reactant: 695543

695519
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stoichiometry: 1.0
species: 302492

302492
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Adenosine_C10H13N5O4

695531
type: SpeciesReference
stoichiometry: 1.0
species: 302659

695555
type: SpeciesReference
stoichiometry: 1.0
species: 302686

302686
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Inosine_C10H12N4O5

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type: SpeciesReference
stoichiometry: 1.0
species: 302725

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303867
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value: 0.0

303866
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value: 999999.0

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value: 0.0

695543
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303314
type: Reaction
kinetic law: 703970
product: 703958
reactant: 703946
notes: Abbreviation: R_EX_his_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : his-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Histidine exchange

304426
type: LocalParameter
value: 0.0

304425
type: LocalParameter
value: 0.0

304424
type: LocalParameter
value: 999999.0

304423
type: LocalParameter
value: 0.0

703958
type: SpeciesReference
stoichiometry: 1.0
species: 303036

303036
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Histidine_C6H9N3O2

703946
type: SpeciesReference
stoichiometry: 1.0
species: 302667

302667
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Histidine_C6H9N3O2

302963
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405

302989
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Uridine_C9H12N2O6

303247
type: Reaction
kinetic law: 702301
product: 702289
product: 702277
reactant: 702265
notes: Abbreviation: R_DHQD Synonyms: _0 EC Number: 4.2.1.10 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : 3dhq <==> 3dhsk + h2o Confidence Level: 2 genes: LOCUS:BLBBGE_083#ABBREVIATION:aroD#ECNUMBERS:4.2.1.10# proteins: NAME:_3-dehydroquinate dehydratase#ABBREVIATION:AroD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_083)
fast: false
reversible: true
name: _3-dehydroquinate dehydratase

304266
type: LocalParameter
value: 0.0

304265
type: LocalParameter
value: 0.0

304264
type: LocalParameter
value: 999999.0

304263
type: LocalParameter
value: -999999.0

702289
type: SpeciesReference
stoichiometry: 1.0
species: 302655

702277
type: SpeciesReference
stoichiometry: 1.0
species: 302440

302440
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Dehydroshikimate_C7H7O5

702265
type: SpeciesReference
stoichiometry: 1.0
species: 302438

302518
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N(omega)-(L-Arginino)succinate_C10H17N4O6

303157
type: Reaction
name: aspartate transaminase
reactant: 698078
reactant: 698065
kinetic law: 698117
product: 698091
fast: false
notes: Abbreviation: R_ASPTA Synonyms: _29 EC Number: 2.6.1.1 SUBSYSTEM: Alanine and Aspartate Metabolism Equation: [c] : akg + asp-L <==> glu-L + oaa Confidence Level: 2 genes: LOCUS:BLBBGE_355#ABBREVIATION:aspC#ECNUMBERS:2.6.1.1# proteins: NAME:aspartate aminotransferase#ABBREVIATION:AspC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_355)
reversible: true
product: 698104

698078
type: SpeciesReference
stoichiometry: 1.0
species: 302522

698065
type: SpeciesReference
stoichiometry: 1.0
species: 302500

304046
type: LocalParameter
value: 0.0

304045
type: LocalParameter
value: 0.0

304044
type: LocalParameter
value: 999999.0

304042
type: LocalParameter
value: -999999.0

698091
type: SpeciesReference
stoichiometry: 1.0
species: 302633

698104
type: SpeciesReference
stoichiometry: 1.0
species: 302738

302738
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Oxaloacetate_C4H2O5

303667
type: Reaction
kinetic law: 715117
product: 715093
reactant: 715057
name: pantothenate kinase
notes: Abbreviation: R_PNTK Synonyms: _0 EC Number: 2.7.1.33 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + pnto-R --> 4ppan + adp + h Confidence Level: 2 genes: LOCUS:BLBBGE_132#ABBREVIATION:coaA#ECNUMBERS:2.7.1.33# proteins: NAME:pantothenate kinase#ABBREVIATION:CoaA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_132)
product: 715081
fast: false
reversible: false
product: 715105
reactant: 715069

305316
type: LocalParameter
value: 0.0

305315
type: LocalParameter
value: 0.0

305314
type: LocalParameter
value: 999999.0

305313
type: LocalParameter
value: 0.0

715093
type: SpeciesReference
stoichiometry: 1.0
species: 302493

715057
type: SpeciesReference
stoichiometry: 1.0
species: 302526

715081
type: SpeciesReference
stoichiometry: 1.0
species: 302458

302458
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-4'-Phosphopantothenate_C9H15NO8P

715105
type: SpeciesReference
stoichiometry: 1.0
species: 302659

715069
type: SpeciesReference
stoichiometry: 1.0
species: 302858

302858
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (R)-Pantothenate_C9H16NO5

302426
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Isopropylmaleate_C7H8O4

303762
type: Reaction
product: 719762
product: 719774
kinetic law: 719811
reactant: 719738
product: 719786
reactant: 719726
fast: false
reversible: false
name: L-threonine transport via ABC system
product: 719799
notes: Abbreviation: R_THRabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + thr-L[e] --> adp[c] + h[c] + pi[c] + thr-L[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 719750

719762
type: SpeciesReference
stoichiometry: 1.0
species: 302493

719774
type: SpeciesReference
stoichiometry: 1.0
species: 302659

305651
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value: 0.0

305650
type: LocalParameter
value: 0.0

305649
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value: 999999.0

305648
type: LocalParameter
value: 0.0

719738
type: SpeciesReference
stoichiometry: 1.0
species: 302655

719786
type: SpeciesReference
stoichiometry: 1.0
species: 302853

719726
type: SpeciesReference
stoichiometry: 1.0
species: 302526

719799
type: SpeciesReference
stoichiometry: 1.0
species: 302940

302940
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Threonine_C4H9NO3

719750
type: SpeciesReference
stoichiometry: 1.0
species: 302943

302943
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Threonine_C4H9NO3

302710
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Menaquinone 8_C51H72O2

302636
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Glycine_C2H5NO2

302544
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Cystathionine_C7H14N2O4S

303429
type: Reaction
product: 706955
notes: Abbreviation: R_GRTT Synonyms: _0 EC Number: 2.5.1.10 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : grdp + ipdp --> frdp + ppi Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 706943
reactant: 706931
product: 706967
reversible: false
kinetic law: 706979
name: geranyltranstransferase
fast: false

706955
type: SpeciesReference
stoichiometry: 1.0
species: 302613

302613
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Farnesyl diphosphate_C15H25O7P2

706943
type: SpeciesReference
stoichiometry: 1.0
species: 302687

302687
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Isopentenyl diphosphate_C5H9O7P2

706931
type: SpeciesReference
stoichiometry: 1.0
species: 302649

302649
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Geranyl diphosphate_C10H17O7P2

706967
type: SpeciesReference
stoichiometry: 1.0
species: 302865

304675
type: LocalParameter
value: 0.0

304674
type: LocalParameter
value: 0.0

304673
type: LocalParameter
value: 999999.0

304672
type: LocalParameter
value: 0.0

303630
type: Reaction
product: 713805
product: 713793
notes: Abbreviation: R_OMPDC Synonyms: _0 EC Number: 4.1.1.23 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : h + orot5p --> co2 + ump Confidence Level: 2 genes: LOCUS:BLBBGE_512#ABBREVIATION:pyrFE#ECNUMBERS:4.1.1.23# proteins: NAME:Orotidine 5'-phosphate decarboxylase-Orotate phosphoribosyltransferase#ABBREVIATION:PyrFE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_512)
name: orotidine-5'-phosphate decarboxylase
reversible: false
kinetic law: 713818
fast: false
reactant: 713781
reactant: 713769

713805
type: SpeciesReference
stoichiometry: 1.0
species: 302980

713793
type: SpeciesReference
stoichiometry: 1.0
species: 302536

305219
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value: 0.0

305218
type: LocalParameter
value: 0.0

305217
type: LocalParameter
value: 999999.0

305216
type: LocalParameter
value: 0.0

713781
type: SpeciesReference
stoichiometry: 1.0
species: 302745

302745
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Orotidine 5'-phosphate_C10H10N2O11P

713769
type: SpeciesReference
stoichiometry: 1.0
species: 302659

302925
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Succinate_C4H4O4

303414
type: Reaction
kinetic law: 706497
product: 706485
reactant: 706473
notes: Abbreviation: R_GLYALDt Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: glyald[e] <==> glyald[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_460#ABBREVIATION:glpF# proteins: NAME:MIP channel, glycerol diffusion#ABBREVIATION:GlpF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_460)
fast: false
reversible: true
name: Glyceraldehyde facilitated diffusion

304645
type: LocalParameter
value: 0.0

304644
type: LocalParameter
value: 0.0

304643
type: LocalParameter
value: 999999.0

304642
type: LocalParameter
value: -999999.0

706485
type: SpeciesReference
stoichiometry: 1.0
species: 302638

706473
type: SpeciesReference
stoichiometry: 1.0
species: 302640

303134
type: Reaction
reactant: 697090
kinetic law: 697127
fast: false
name: alanine transaminase
product: 697102
reactant: 697078
reversible: false
product: 697114
notes: Abbreviation: R_ALATA_L2 Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : ala-L + pydx5p --> pyam5p + pyr Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:

697090
type: SpeciesReference
stoichiometry: 1.0
species: 302889

302889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Pyridoxal 5'-phosphate_C8H8NO6P

303982
type: LocalParameter
value: 0.0

303981
type: LocalParameter
value: 0.0

303980
type: LocalParameter
value: 999999.0

303978
type: LocalParameter
value: 0.0

697102
type: SpeciesReference
stoichiometry: 1.0
species: 302888

302888
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Pyridoxamine 5'-phosphate_C8H12N2O5P

697078
type: SpeciesReference
stoichiometry: 1.0
species: 302504

302504
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Alanine_C3H7NO2

697114
type: SpeciesReference
stoichiometry: 1.0
species: 302893

303293
type: Reaction
kinetic law: 703569
product: 703557
reactant: 703545
notes: Abbreviation: R_EX_for_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : for <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Formate exchange

304376
type: LocalParameter
value: 0.0

304375
type: LocalParameter
value: 0.0

304374
type: LocalParameter
value: 999999.0

304373
type: LocalParameter
value: 0.0

703557
type: SpeciesReference
stoichiometry: 1.0
species: 303019

303019
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Formate_CH1O2

703545
type: SpeciesReference
stoichiometry: 1.0
species: 302609

302609
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Formate_CH1O2

303720
type: Reaction
notes: Abbreviation: R_PYDXPP Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : h2o + pydx5p --> pi + pydx Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 717419
reactant: 717431
kinetic law: 717467
product: 717443
fast: false
name: Pyridoxal 5-phosphate phosphatase
reversible: false
product: 717455

717419
type: SpeciesReference
stoichiometry: 1.0
species: 302655

717431
type: SpeciesReference
stoichiometry: 1.0
species: 302889

305486
type: LocalParameter
value: 0.0

305485
type: LocalParameter
value: 0.0

305484
type: LocalParameter
value: 999999.0

305483
type: LocalParameter
value: 0.0

717443
type: SpeciesReference
stoichiometry: 1.0
species: 302853

717455
type: SpeciesReference
stoichiometry: 1.0
species: 302890

302890
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Pyridoxal_C8H9NO3

303603
type: Reaction
name: Nucleoside triphosphate pyrophosphorylase (ctp)
product: 712970
product: 712958
notes: Abbreviation: R_NTPP4 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : ctp + h2o --> cmp + h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
reversible: false
kinetic law: 712982
product: 712946
fast: false
reactant: 712922
reactant: 712934

712970
type: SpeciesReference
stoichiometry: 1.0
species: 302865

712958
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stoichiometry: 1.0
species: 302659

305063
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value: 0.0

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value: 0.0

305061
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value: 999999.0

305060
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value: 0.0

712946
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stoichiometry: 1.0
species: 302534

302534
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: CMP_C9H12N3O8P

712922
type: SpeciesReference
stoichiometry: 1.0
species: 302541

712934
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303578
type: Reaction
reversible: false
name: _5'-nucleotidase (XMP)
reactant: 712109
reactant: 712097
kinetic law: 712145
product: 712133
product: 712121
fast: false
notes: Abbreviation: R_NTD10 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : h2o + xmp --> pi + xtsn Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:

712109
type: SpeciesReference
stoichiometry: 1.0
species: 302998

302998
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Xanthosine 5'-phosphate_C10H11N4O9P

712097
type: SpeciesReference
stoichiometry: 1.0
species: 302655

305005
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value: 0.0

305004
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value: 0.0

305003
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value: 999999.0

305002
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value: 0.0

712133
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stoichiometry: 1.0
species: 302999

302999
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Xanthosine_C10H12N4O6

712121
type: SpeciesReference
stoichiometry: 1.0
species: 302853

303161
type: Reaction
product: 698245
reactant: 698209
reversible: true
product: 698257
fast: false
kinetic law: 698269
product: 698233
notes: Abbreviation: R_ATPS4r Synonyms: _0 EC Number: 3.6.3.14 SUBSYSTEM: Oxidative Phosphorylation Equation: adp[c] + (4) h[e] + pi[c] <==> atp[c] + (3) h[c] + h2o[c] Confidence Level: 2 JLR- added reversible form of ATPS4 reactioin genes: LOCUS:BLBBGE_074#ABBREVIATION:atpC#ECNUMBERS:3.6.3.14# LOCUS:BLBBGE_073#ABBREVIATION:atpD#ECNUMBERS:3.6.3.14# LOCUS:BLBBGE_562#ABBREVIATION:atpG#ECNUMBERS:3.6.3.14# LOCUS:BLBBGE_563#ABBREVIATION:atpA#ECNUMBERS:3.6.3.14# LOCUS:BLBBGE_564#ABBREVIATION:atpH#ECNUMBERS:3.6.3.14# LOCUS:BLBBGE_565#ABBREVIATION:atpF#ECNUMBERS:3.6.3.14# LOCUS:BLBBGE_566#ABBREVIATION:atpE#ECNUMBERS:3.6.3.14# LOCUS:BLBBGE_567#ABBREVIATION:atpB#ECNUMBERS:3.6.3.14# proteins: NAME:ATP synthase F1#ABBREVIATION:AtpF1# NAME:ATP synthase F0#ABBREVIATION:AtpF0# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_566 and BLBBGE_565 and BLBBGE_567) and (BLBBGE_564 and BLBBGE_563 and BLBBGE_562 and BLBBGE_073 and BLBBGE_074)
name: ATP synthase (four protons for one ATP)
reactant: 698221
reactant: 698196

698245
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stoichiometry: 3.0
species: 302659

698209
type: SpeciesReference
stoichiometry: 4.0
species: 302660

698257
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stoichiometry: 1.0
species: 302655

304054
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value: 0.0

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value: 0.0

304052
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value: 999999.0

304051
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value: -999999.0

698233
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stoichiometry: 1.0
species: 302526

698221
type: SpeciesReference
stoichiometry: 1.0
species: 302853

698196
type: SpeciesReference
stoichiometry: 1.0
species: 302493

303239
type: Reaction
reactant: 702036
product: 702048
reversible: false
name: dihydroorotic acid (menaquinone-8)
reactant: 702024
kinetic law: 702072
notes: Abbreviation: R_DHORD5 Synonyms: _0 EC Number: 1.3.3.1 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : dhor-S + mqn8 --> mql8 + orot Confidence Level: 2 JLR genes: LOCUS:BLBBGE_513#ABBREVIATION:pyrD#ECNUMBERS:1.3.3.1# proteins: NAME:Dihydroorotate dehydrogenase#ABBREVIATION:PyrD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_513)
fast: false
product: 702060

702036
type: SpeciesReference
stoichiometry: 1.0
species: 302710

702048
type: SpeciesReference
stoichiometry: 1.0
species: 302709

302709
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Menaquinol 8_C51H74O2

702024
type: SpeciesReference
stoichiometry: 1.0
species: 302571

302571
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (S)-Dihydroorotate_C5H5N2O4

304248
type: LocalParameter
value: 0.0

304247
type: LocalParameter
value: 0.0

304246
type: LocalParameter
value: 999999.0

304245
type: LocalParameter
value: 0.0

702060
type: SpeciesReference
stoichiometry: 1.0
species: 302748

303406
type: Reaction
reactant: 706196
reactant: 706220
reversible: true
product: 706256
product: 706232
notes: Abbreviation: R_GLUDy Synonyms: _0 EC Number: 1.4.1.4 SUBSYSTEM: Glutamate metabolism Equation: [c] : glu-L + h2o + nadp <==> akg + h + nadph + nh4 Confidence Level: 2 genes: LOCUS:BLBBGE_121#ABBREVIATION:gdhA#ECNUMBERS:1.4.1.4# proteins: NAME:Glutamate dehydrogenase#ABBREVIATION:GdhA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_121)
fast: false
reactant: 706208
name: glutamate dehydrogenase (NADP)
product: 706244
product: 706268
kinetic law: 706280

706196
type: SpeciesReference
stoichiometry: 1.0
species: 302633

706220
type: SpeciesReference
stoichiometry: 1.0
species: 302723

302723
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

706256
type: SpeciesReference
stoichiometry: 1.0
species: 302724

302724
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

706232
type: SpeciesReference
stoichiometry: 1.0
species: 302500

706208
type: SpeciesReference
stoichiometry: 1.0
species: 302655

706244
type: SpeciesReference
stoichiometry: 1.0
species: 302659

706268
type: SpeciesReference
stoichiometry: 1.0
species: 302725

304627
type: LocalParameter
value: 0.0

304626
type: LocalParameter
value: 0.0

304625
type: LocalParameter
value: 999999.0

304624
type: LocalParameter
value: -999999.0

302908
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Serine_C3H7NO3

303659
type: Reaction
product: 714841
reactant: 714817
reactant: 714829
reversible: true
name: phenylalanine transaminase
product: 714853
fast: false
kinetic law: 714865
notes: Abbreviation: R_PHETA1 Synonyms: _5 EC Number: 2.6.1.58 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : akg + phe-L <==> glu-L + phpyr Confidence Level: 2 genes: LOCUS:BLBBGE_355#ABBREVIATION:aspC#ECNUMBERS:2.6.1.1# LOCUS:BLBBGE_455#ABBREVIATION:ilvE#ECNUMBERS:2.6.1.42,-!-,2.6.1.2# LOCUS:BLBBGE_342#ABBREVIATION:tyrB#ECNUMBERS:2.6.1.57# proteins: NAME:Tyrosine aminotransferase#ABBREVIATION:TyrB# NAME:Branched-chain-amino-acid aminotransferase#ABBREVIATION:IlvE# NAME:aspartate aminotransferase#ABBREVIATION:AspC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_455) or (BLBBGE_342) or (BLBBGE_355)

714841
type: SpeciesReference
stoichiometry: 1.0
species: 302633

714817
type: SpeciesReference
stoichiometry: 1.0
species: 302500

714829
type: SpeciesReference
stoichiometry: 1.0
species: 302764

302764
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Phenylalanine_C9H11NO2

714853
type: SpeciesReference
stoichiometry: 1.0
species: 302769

305294
type: LocalParameter
value: 0.0

305293
type: LocalParameter
value: 0.0

305292
type: LocalParameter
value: 999999.0

305291
type: LocalParameter
value: -999999.0

303773
type: Reaction
kinetic law: 720342
product: 720330
reactant: 720318
notes: Abbreviation: R_TPI Synonyms: _0 EC Number: 5.3.1.1 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : dhap <==> g3p Confidence Level: 2 SMP genes: LOCUS:BLBBGE_104#ABBREVIATION:tpiA#ECNUMBERS:5.3.1.1# proteins: NAME:triosephosphate isomerase#ABBREVIATION:Tpi# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_104)
fast: false
reversible: true
name: triose-phosphate isomerase

305696
type: LocalParameter
value: 0.0

305695
type: LocalParameter
value: 0.0

305694
type: LocalParameter
value: 999999.0

305693
type: LocalParameter
value: -999999.0

720330
type: SpeciesReference
stoichiometry: 1.0
species: 302620

720318
type: SpeciesReference
stoichiometry: 1.0
species: 302566

303712
type: Reaction
notes: Abbreviation: R_PUNP4 Synonyms: _0 EC Number: 2.4.2.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dgsn + pi <==> 2dr1p + gua Confidence Level: 2 Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase genes: LOCUS:BLBBGE_377#ABBREVIATION:pndA#ECNUMBERS:2.4.2.1# proteins: NAME:purine-nucleoside phosphorylase#ABBREVIATION:PndA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)
reactant: 717032
product: 717044
kinetic law: 717068
name: purine-nucleoside phosphorylase (Deoxyguanosine)
reactant: 717020
product: 717056
reversible: true
fast: false

717032
type: SpeciesReference
stoichiometry: 1.0
species: 302853

717044
type: SpeciesReference
stoichiometry: 1.0
species: 302425

305456
type: LocalParameter
value: 0.0

305455
type: LocalParameter
value: 0.0

305454
type: LocalParameter
value: 999999.0

305453
type: LocalParameter
value: -999999.0

717020
type: SpeciesReference
stoichiometry: 1.0
species: 302564

302564
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Deoxyguanosine_C10H13N5O4

717056
type: SpeciesReference
stoichiometry: 1.0
species: 302652

302652
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Guanine_C5H5N5O

303198
type: Reaction
fast: false
name: cytochrome oxidase bo3 (ubiquinol-8: 2.5 protons)
product: 700559
product: 700547
product: 700535
reversible: false
reactant: 700511
reactant: 700499
reactant: 700523
kinetic law: 700571
notes: Abbreviation: R_CYTBO3 Synonyms: _0 SUBSYSTEM: Oxidative Phosphorylation Equation: (2.5) h[c] + (0.5) o2[c] + mql8[c] --> (2.5) h[e] + h2o[c] + mqn8[c] Confidence Level: 2 EC Number: 1.9.3.1 genes: LOCUS:BLBBGE_414#ABBREVIATION:cyoC#ECNUMBERS:1.9.3.1# LOCUS:BLBBGE_416#ABBREVIATION:cyoBA#ECNUMBERS:1.9.3.1# proteins: NAME:cytochrome oxidase bo3#ABBREVIATION:CyoABC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_414 and BLBBGE_416)

700559
type: SpeciesReference
stoichiometry: 1.0
species: 302710

700547
type: SpeciesReference
stoichiometry: 1.0
species: 302655

700535
type: SpeciesReference
stoichiometry: 2.5
species: 302660

700511
type: SpeciesReference
stoichiometry: 0.5
species: 302733

302733
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: O2_O2

700499
type: SpeciesReference
stoichiometry: 2.5
species: 302659

700523
type: SpeciesReference
stoichiometry: 1.0
species: 302709

304146
type: LocalParameter
value: 0.0

304145
type: LocalParameter
value: 0.0

304144
type: LocalParameter
value: 999999.0

304143
type: LocalParameter
value: 0.0

303107
type: Reaction
name: adenosine kinase
fast: false
reversible: true
product: 695975
product: 695987
notes: Abbreviation: R_ADNK1 Synonyms: _0 EC Number: 2.7.1.20 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : adn + atp <==> adp + amp + h Confidence Level: 2 _2-Aminoadenosine can also act as acceptor genes: LOCUS:BLBBGE_215#ABBREVIATION:adk#ECNUMBERS:2.7.4.3# proteins: NAME:Adenylate kinase#ABBREVIATION:Adk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_215)
product: 695999
reactant: 695963
kinetic law: 696011
reactant: 695951

695975
type: SpeciesReference
stoichiometry: 1.0
species: 302493

695987
type: SpeciesReference
stoichiometry: 1.0
species: 302511

695999
type: SpeciesReference
stoichiometry: 1.0
species: 302659

695963
type: SpeciesReference
stoichiometry: 1.0
species: 302526

303900
type: LocalParameter
value: 0.0

303899
type: LocalParameter
value: 0.0

303898
type: LocalParameter
value: 999999.0

303897
type: LocalParameter
value: -999999.0

695951
type: SpeciesReference
stoichiometry: 1.0
species: 302492

302473
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _6-hydroxymethyl dihydropterin_C7H9N5O2

302499
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-amino-1-(5-phospho-D-ribosyl)imidazole_C8H12N3O7P

303686
type: Reaction
name: Peptidoglycan subunit synthesis
fast: false
product: 715687
notes: Abbreviation: R_PPTGS_Bge Synonyms: _0 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : uaagmda --> h + peptido_Bge + udcpdp Confidence Level: 2 JLR- the production of a subunit of peptidoglycantv- H pylori also uses the same form genes: LOCUS:BLBBGE_284#ABBREVIATION:mrcA#ECNUMBERS:2.4.1.129# proteins: NAME:peptidoglycan synthetase; penicillin-binding protein 1A#ABBREVIATION:MrcA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_284)
reversible: false
product: 715700
reactant: 715662
product: 715675
kinetic law: 715713

715687
type: SpeciesReference
stoichiometry: 1.0
species: 302763

302763
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Peptidoglycan subunit of Blattabacterium Blattella germanica_C40H62N8O21

715700
type: SpeciesReference
stoichiometry: 1.0
species: 302973

302973
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Undecaprenyl diphosphate_C55H89O7P2

715662
type: SpeciesReference
stoichiometry: 1.0
species: 302960

302960
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405

715675
type: SpeciesReference
stoichiometry: 1.0
species: 302659

305358
type: LocalParameter
value: 0.0

305357
type: LocalParameter
value: 0.0

305356
type: LocalParameter
value: 999999.0

305355
type: LocalParameter
value: 0.0

303727
type: Reaction
reversible: false
fast: false
product: 717841
name: ribonucleoside-diphosphate reductase (GDP)
reactant: 717805
reactant: 717817
product: 717829
product: 717853
notes: Abbreviation: R_RNDR2 Synonyms: _0 EC Number: 1.17.4.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : gdp + trdrd --> dgdp + h2o + trdox Confidence Level: 2 genes: LOCUS:BLBBGE_310#ABBREVIATION:nrdA#ECNUMBERS:1.17.4.1# LOCUS:BLBBGE_p006#ABBREVIATION:nrdF#ECNUMBERS:1.17.4.1# proteins: NAME:ribonucleoside-diphosphate reductase subunit alpha#ABBREVIATION:NrdA# NAME:ribonucleotide-diphosphate reductase beta subunit#ABBREVIATION:NrdF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_310 and BLBBGE_p006)
kinetic law: 717865

717841
type: SpeciesReference
stoichiometry: 1.0
species: 302655

717805
type: SpeciesReference
stoichiometry: 1.0
species: 302626

717817
type: SpeciesReference
stoichiometry: 1.0
species: 302949

717829
type: SpeciesReference
stoichiometry: 1.0
species: 302561

717853
type: SpeciesReference
stoichiometry: 1.0
species: 302948

305516
type: LocalParameter
value: 0.0

305515
type: LocalParameter
value: 0.0

305514
type: LocalParameter
value: 999999.0

305513
type: LocalParameter
value: 0.0

303325
type: Reaction
kinetic law: 704151
product: 704138
reactant: 704126
notes: Abbreviation: R_EX_mal_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : mal-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Malate exchange

304448
type: LocalParameter
value: 0.0

304447
type: LocalParameter
value: 0.0

304446
type: LocalParameter
value: 999999.0

304445
type: LocalParameter
value: 0.0

704138
type: SpeciesReference
stoichiometry: 1.0
species: 303045

303045
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Malate_C4H4O5

704126
type: SpeciesReference
stoichiometry: 1.0
species: 302700

302700
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Malate_C4H4O5

303208
type: Reaction
product: 700958
fast: false
kinetic law: 700970
name: deoxyadenylate kinase
reactant: 700921
product: 700945
reversible: true
notes: Abbreviation: R_DADK Synonyms: _0 EC Number: 2.7.4.11 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + damp <==> adp + dadp Confidence Level: 2 AMP can also act as acceptor genes: LOCUS:BLBBGE_215#ABBREVIATION:adk#ECNUMBERS:2.7.4.3# proteins: NAME:Adenylate kinase#ABBREVIATION:Adk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_215)
reactant: 700933

700958
type: SpeciesReference
stoichiometry: 1.0
species: 302548

304174
type: LocalParameter
value: 0.0

304173
type: LocalParameter
value: 0.0

304172
type: LocalParameter
value: 999999.0

304171
type: LocalParameter
value: -999999.0

700921
type: SpeciesReference
stoichiometry: 1.0
species: 302526

700945
type: SpeciesReference
stoichiometry: 1.0
species: 302493

700933
type: SpeciesReference
stoichiometry: 1.0
species: 302550

302550
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dAMP_C10H12N5O6P

303514
type: Reaction
reactant: 709935
product: 709971
product: 709996
kinetic law: 710008
fast: false
notes: Abbreviation: R_METabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + met-L[e] --> adp[c] + h[c] + met-L[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 709959
name: L-methionine transport via ABC system
product: 709983
reactant: 709923
reactant: 709947
reversible: false

709935
type: SpeciesReference
stoichiometry: 1.0
species: 302655

709971
type: SpeciesReference
stoichiometry: 1.0
species: 302659

709996
type: SpeciesReference
stoichiometry: 1.0
species: 302853

304863
type: LocalParameter
value: 0.0

304862
type: LocalParameter
value: 0.0

304861
type: LocalParameter
value: 999999.0

304860
type: LocalParameter
value: 0.0

709959
type: SpeciesReference
stoichiometry: 1.0
species: 302493

709983
type: SpeciesReference
stoichiometry: 1.0
species: 302702

302702
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Methionine_C5H11NO2S

709923
type: SpeciesReference
stoichiometry: 1.0
species: 302526

709947
type: SpeciesReference
stoichiometry: 1.0
species: 302704

302704
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Methionine_C5H11NO2S

303671
type: Reaction
reversible: false
fast: false
product: 715225
notes: Abbreviation: R_PPA Synonyms: _3 EC Number: 3.6.1.1 SUBSYSTEM: Anaplerotic reactions Equation: [c] : h2o + ppi --> h + (2) pi Confidence Level: 2 genes: LOCUS:BLBBGE_010#ABBREVIATION:ppa#ECNUMBERS:3.6.1.1# proteins: NAME:inorganic pyrophosphatase#ABBREVIATION:Ppa# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_010)
name: inorganic diphosphatase
product: 715213
reactant: 715189
kinetic law: 715237
reactant: 715201

715225
type: SpeciesReference
stoichiometry: 2.0
species: 302853

715213
type: SpeciesReference
stoichiometry: 1.0
species: 302659

715189
type: SpeciesReference
stoichiometry: 1.0
species: 302655

305327
type: LocalParameter
value: 0.0

305325
type: LocalParameter
value: 0.0

305324
type: LocalParameter
value: 999999.0

305322
type: LocalParameter
value: 0.0

715201
type: SpeciesReference
stoichiometry: 1.0
species: 302865

302456
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _4-Phospho-D-erythronate_C4H6O8P

302662
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Bicarbonate_CHO3

302409
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _1-Pyrroline-5-carboxylate_C5H6NO2

302570
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Dihydroneopterin_C9H13N5O4

303037
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Isoleucine_C6H13NO2

302527
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Carbamoyl phosphate_CH2NO5P

302435
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Carboxy-2-hydroxy-4-methylpentanoate_C7H10O5

302645
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Glycolate_C2H3O3

302418
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (S)-2-Aceto-2-hydroxybutanoate_C6H9O4

302624
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N1-(5-Phospho-D-ribosyl)glycinamide_C7H14N2O8P

302587
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dUDP_C9H11N2O11P2

303522
type: Reaction
kinetic law: 710274
product: 710261
reactant: 710249
reactant: 710237
notes: Abbreviation: R_MTHFC Synonyms: _0 EC Number: 3.5.4.9 SUBSYSTEM: Folate Metabolism Equation: [c] : h2o + methf <==> 10fthf Confidence Level: 2 genes: LOCUS:BLBBGE_442#ABBREVIATION:folD#ECNUMBERS:1.5.1.5,-!-,3.5.4.9# proteins: NAME:Methylene-tetrahydrofolate dehydrogenase#ABBREVIATION:FolD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_442)
fast: false
reversible: true
name: methenyltetrahydrofolate cyclohydrolase

304881
type: LocalParameter
value: 0.0

304880
type: LocalParameter
value: 0.0

304879
type: LocalParameter
value: 999999.0

304878
type: LocalParameter
value: -999999.0

710261
type: SpeciesReference
stoichiometry: 1.0
species: 302407

302407
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _10-Formyltetrahydrofolate_C20H21N7O7

710249
type: SpeciesReference
stoichiometry: 1.0
species: 302705

710237
type: SpeciesReference
stoichiometry: 1.0
species: 302655

302728
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Ammonium_H4N

303434
type: Reaction
reactant: 707136
reactant: 707160
kinetic law: 707196
product: 707172
product: 707184
name: guanine deaminase
notes: Abbreviation: R_GUAD Synonyms: _0 EC Number: 3.5.4.3 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : gua + h + h2o --> nh4 + xan Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 707148
fast: false
reversible: false

707136
type: SpeciesReference
stoichiometry: 1.0
species: 302652

707160
type: SpeciesReference
stoichiometry: 1.0
species: 302655

304687
type: LocalParameter
value: 0.0

304686
type: LocalParameter
value: 0.0

304685
type: LocalParameter
value: 999999.0

304684
type: LocalParameter
value: 0.0

707172
type: SpeciesReference
stoichiometry: 1.0
species: 302725

707184
type: SpeciesReference
stoichiometry: 1.0
species: 302995

302995
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Xanthine_C5H4N4O2

707148
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303020
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: D-Fructose_C6H12O6

302934
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5,6,7,8-Tetrahydrofolate_C19H21N7O6

303294
type: Reaction
kinetic law: 703605
product: 703593
reactant: 703581
notes: Abbreviation: R_EX_fru_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : fru <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: D-Fructose exchange

304380
type: LocalParameter
value: 0.0

304379
type: LocalParameter
value: 0.0

304378
type: LocalParameter
value: 999999.0

304377
type: LocalParameter
value: 0.0

703593
type: SpeciesReference
stoichiometry: 1.0
species: 303020

703581
type: SpeciesReference
stoichiometry: 1.0
species: 302616

302616
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: D-Fructose_C6H12O6

303623
type: Reaction
fast: false
reactant: 713575
notes: Abbreviation: R_OHPBAT Synonyms: _0 EC Number: 2.6.1.52 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : glu-L + ohpb <==> akg + phthr Confidence Level: 2 NCD genes: LOCUS:BLBBGE_428#ABBREVIATION:serC#ECNUMBERS:2.6.1.52# LOCUS:BLBBGE_144#ABBREVIATION:serC#ECNUMBERS:2.6.1.52# proteins: NAME:Phosphoserine aminotransferase#ABBREVIATION:SerC# NAME:Phosphoserine aminotransferase#ABBREVIATION:SerC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_428) or (BLBBGE_144)
reversible: true
name: O-Phospho-4-hydroxy-L-threonine:2-oxoglutarate aminotransferase
kinetic law: 713623
product: 713611
reactant: 713587
product: 713599

713575
type: SpeciesReference
stoichiometry: 1.0
species: 302633

305207
type: LocalParameter
value: 0.0

305206
type: LocalParameter
value: 0.0

305205
type: LocalParameter
value: 999999.0

305203
type: LocalParameter
value: -999999.0

713611
type: SpeciesReference
stoichiometry: 1.0
species: 302770

302770
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: O-Phospho-4-hydroxy-L-threonine_C4H8NO7P

713587
type: SpeciesReference
stoichiometry: 1.0
species: 302743

302743
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Oxo-3-hydroxy-4-phosphobutanoate_C4H4O8P

713599
type: SpeciesReference
stoichiometry: 1.0
species: 302500

303080
type: Reaction
product: 694936
fast: false
reversible: false
product: 694924
reactant: 694912
notes: Abbreviation: R_ACGK Synonyms: _0 EC Number: 2.7.2.8 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : acglu + atp --> acg5p + adp Confidence Level: 2 genes: LOCUS:BLBBGE_319#ABBREVIATION:argB#ECNUMBERS:2.7.2.8# proteins: NAME:acetylglutamate kinase#ABBREVIATION:ArgB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_319)
kinetic law: 694948
name: acetylglutamate kinase
reactant: 694900

694936
type: SpeciesReference
stoichiometry: 1.0
species: 302493

694924
type: SpeciesReference
stoichiometry: 1.0
species: 302480

302480
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-Acetyl-L-glutamyl 5-phosphate_C7H9NO8P

694912
type: SpeciesReference
stoichiometry: 1.0
species: 302526

303822
type: LocalParameter
value: 0.0

303821
type: LocalParameter
value: 0.0

303820
type: LocalParameter
value: 999999.0

303819
type: LocalParameter
value: 0.0

694900
type: SpeciesReference
stoichiometry: 1.0
species: 302484

302484
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-Acetyl-L-glutamate_C7H9NO5

303575
type: Reaction
reactant: 712048
reactant: 712035
fast: false
product: 712060
name: _5'-nucleotidase (dUMP)
reversible: false
kinetic law: 712085
notes: Abbreviation: R_NTD1 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dump + h2o --> duri + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 712073

712048
type: SpeciesReference
stoichiometry: 1.0
species: 302655

712035
type: SpeciesReference
stoichiometry: 1.0
species: 302588

302588
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dUMP_C9H11N2O8P

712060
type: SpeciesReference
stoichiometry: 1.0
species: 302589

302589
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Deoxyuridine_C9H12N2O5

305001
type: LocalParameter
value: 0.0

305000
type: LocalParameter
value: 0.0

304999
type: LocalParameter
value: 999999.0

304998
type: LocalParameter
value: 0.0

712073
type: SpeciesReference
stoichiometry: 1.0
species: 302853

303162
type: Reaction
reactant: 698763
reactant: 698281
reactant: 698317
reactant: 698341
reactant: 698522
reactant: 698413
product: 698787
reactant: 698667
reactant: 698485
reactant: 698691
reactant: 698437
reactant: 698606
reactant: 698703
reversible: false
reactant: 698727
reactant: 698534
reactant: 698558
reactant: 698329
reactant: 698643
reactant: 698461
kinetic law: 698836
reactant: 698582
reactant: 698679
reactant: 698497
name: BiomassBge
reactant: 698353
reactant: 698305
reactant: 698377
reactant: 698631
reactant: 698449
reactant: 698389
reactant: 698655
reactant: 698473
reactant: 698715
reactant: 698293
reactant: 698509
reactant: 698775
reactant: 698570
fast: false
reactant: 698594
reactant: 698401
product: 698800
reactant: 698365
product: 698824
reactant: 698619
reactant: 698425
product: 698812
reactant: 698546
notes: Abbreviation: R_BiomassBge Equation: [c] : (0.488) ala-L + (0.001) amp + (0.281) arg-L + (0.229) asn-L + (0.229) asp-L + (45.7318) atp + (0.000006) coa + (0.126) ctp + (0.087) cys-L + (0.0365) datp + (0.0135) dctp + (0.0135) dgtp + (0.0365) dttp + (0.00001) fad + (0.25) gln-L + (0.25) glu-L + (0.582) gly + (0.203) gtp + (45.5608) h2o + (0.09) his-L + (0.276) ile-L + (0.428) leu-L + (0.326) lys-L + (0.146) met-L + (0.00215) nad + (0.00005) nadh + (0.00013) nadp + (0.0004) nadph + (0.001935) pe_Bge + (0.0276) peptido_Bge + (0.176) phe-L + (0.21) pro-L + (0.000052) ps_Bge + (0.035) ptrc + (0.205) ser-L + (0.000223) thf + (0.000223) thmpp[c] + (0.241) thr-L + (0.054) trp-L + (0.131) tyr-L + (0.136) utp + (0.402) val-L --> (45.5608) adp + (45.56035) h + (45.5628) pi + (0.7302) ppi Confidence Level: genes: none proteins: none citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION:
reactant: 698739
reactant: 698751

698763
type: SpeciesReference
stoichiometry: 0.136
species: 302990

698281
type: SpeciesReference
stoichiometry: 0.488
species: 302504

698317
type: SpeciesReference
stoichiometry: 0.229
species: 302519

302519
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Asparagine_C4H8N2O3

698341
type: SpeciesReference
stoichiometry: 45.7318
species: 302526

698522
type: SpeciesReference
stoichiometry: 0.276
species: 302679

698413
type: SpeciesReference
stoichiometry: 0.0135
species: 302565

698787
type: SpeciesReference
stoichiometry: 45.5608
species: 302493

698667
type: SpeciesReference
stoichiometry: 5.2E-5
species: 302883

698485
type: SpeciesReference
stoichiometry: 0.203
species: 302651

698691
type: SpeciesReference
stoichiometry: 0.205
species: 302905

302905
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Serine_C3H7NO3

698437
type: SpeciesReference
stoichiometry: 1.0E-5
species: 302598

302598
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

698606
type: SpeciesReference
stoichiometry: 4.0E-4
species: 302724

698703
type: SpeciesReference
stoichiometry: 2.23E-4
species: 302934

698727
type: SpeciesReference
stoichiometry: 0.241
species: 302940

698534
type: SpeciesReference
stoichiometry: 0.428
species: 302692

698558
type: SpeciesReference
stoichiometry: 0.146
species: 302702

698329
type: SpeciesReference
stoichiometry: 0.229
species: 302522

698643
type: SpeciesReference
stoichiometry: 0.176
species: 302764

698461
type: SpeciesReference
stoichiometry: 0.25
species: 302633

304058
type: LocalParameter
value: 0.0

304057
type: LocalParameter
value: 1.0

304056
type: LocalParameter
value: 999999.0

304055
type: LocalParameter
value: 0.0

698582
type: SpeciesReference
stoichiometry: 5.0E-5
species: 302720

698679
type: SpeciesReference
stoichiometry: 0.035
species: 302885

698497
type: SpeciesReference
stoichiometry: 45.5608
species: 302655

698353
type: SpeciesReference
stoichiometry: 6.0E-6
species: 302538

302538
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Coenzyme A_C21H32N7O16P3S

698305
type: SpeciesReference
stoichiometry: 0.281
species: 302516

302516
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Arginine_C6H15N4O2

698377
type: SpeciesReference
stoichiometry: 0.087
species: 302542

302542
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Cysteine_C3H7NO2S

698631
type: SpeciesReference
stoichiometry: 0.0276
species: 302763

698449
type: SpeciesReference
stoichiometry: 0.25
species: 302628

698389
type: SpeciesReference
stoichiometry: 0.0365
species: 302551

302551
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dATP_C10H12N5O12P3

698655
type: SpeciesReference
stoichiometry: 0.21
species: 302878

302878
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Proline_C5H9NO2

698473
type: SpeciesReference
stoichiometry: 0.582
species: 302636

698715
type: SpeciesReference
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initial concentration: NaN
initial amount: NaN
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name: Thiamine diphosphate_C12H16N4O7P2S

698293
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698509
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species: 302666

302666
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initial concentration: NaN
initial amount: NaN
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name: L-Histidine_C6H9N3O2

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species: 302993

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initial concentration: NaN
initial amount: NaN
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name: L-Valine_C5H11NO2

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species: 302719

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species: 302723

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species: 302557

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initial concentration: NaN
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name: dCTP_C9H12N3O13P3

698800
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species: 302659

698365
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species: 302541

698824
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species: 302759

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initial concentration: NaN
initial amount: NaN
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698425
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species: 302585

302585
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: dTTP_C10H13N2O14P3

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species: 302853

698546
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species: 302694

302694
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: L-Lysine_C6H15N2O2

698739
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species: 302950

302950
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: L-Tryptophan_C11H12N2O2

698751
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stoichiometry: 0.131
species: 302954

302452
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: _4-Hydroxy-L-threonine_C4H9NO4

303003
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Acetate_C2H3O2

302684
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Indole_C8H7N

303638
type: Reaction
reversible: false
notes: Abbreviation: R_PAPSR Synonyms: _0 EC Number: 1.8.4.8 SUBSYSTEM: Cysteine Metabolism Equation: [c] : paps + trdrd --> (2) h + pap + so3 + trdox Confidence Level: 2 Previous EC 1.8.99.4. Now EC 1.8.4.8 genes: LOCUS:BLBBGE_273#ABBREVIATION:cysH#ECNUMBERS:1.8.4.8# proteins: NAME:_3'-phosphoadenosine 5'-phosphosulfate reductase#ABBREVIATION:CysH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_273)
name: phosphoadenylyl-sulfate reductase (thioredoxin)
kinetic law: 714095
reactant: 714023
fast: false
product: 714047
product: 714083
reactant: 714035
product: 714071
product: 714059

305238
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305236
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value: 0.0

305235
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value: 999999.0

305233
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value: 0.0

714023
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stoichiometry: 1.0
species: 302755

302755
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3'-Phosphoadenylyl sulfate_C10H11N5O13P2S

714047
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stoichiometry: 2.0
species: 302659

714083
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stoichiometry: 1.0
species: 302948

714035
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species: 302949

714071
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species: 302915

302915
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Sulfite_O3S

714059
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stoichiometry: 1.0
species: 302754

302754
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Adenosine 3',5'-bisphosphate_C10H11N5O10P2

302994
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Valine_C5H11NO2

302523
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Aspartate_C4H6NO4

303687
type: Reaction
product: 715790
reactant: 715726
notes: Abbreviation: R_PRAGSr Synonyms: _1 EC Number: 6.3.4.13 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : atp + gly + pram --> adp + gar + h + pi Confidence Level: 2 JLR- added reversible form of PRAGS genes: LOCUS:BLBBGE_479#ABBREVIATION:purD#ECNUMBERS:6.3.4.13# proteins: NAME:Phosphoribosylglycinamide synthetase#ABBREVIATION:PurD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_479)
product: 715765
product: 715778
reactant: 715752
reactant: 715739
fast: false
kinetic law: 715814
reversible: false
name: phosphoribosylglycinamide synthase
product: 715802

715790
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stoichiometry: 1.0
species: 302659

715726
type: SpeciesReference
stoichiometry: 1.0
species: 302526

715765
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stoichiometry: 1.0
species: 302493

715778
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stoichiometry: 1.0
species: 302624

715752
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stoichiometry: 1.0
species: 302868

302868
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Phospho-beta-D-ribosylamine_C5H11NO7P

715739
type: SpeciesReference
stoichiometry: 1.0
species: 302636

305362
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value: 0.0

305361
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value: 0.0

305360
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value: 999999.0

305359
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value: 0.0

715802
type: SpeciesReference
stoichiometry: 1.0
species: 302853

303747
type: Reaction
fast: false
reversible: false
reactant: 718857
kinetic law: 718905
notes: Abbreviation: R_SPODM Synonyms: _1 EC Number: 1.15.1.1 SUBSYSTEM: Unassigned Equation: [c] : (2) h + (2) o2s --> h2o2 + o2 Confidence Level: 2 JLR genes: LOCUS:BLBBGE_293#ABBREVIATION:sodA#ECNUMBERS:1.15.1.1# proteins: NAME:superoxide dismutase, Mn#ABBREVIATION:SodA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_293)
name: superoxide dismutase
product: 718881
product: 718893
reactant: 718869

718857
type: SpeciesReference
stoichiometry: 2.0
species: 302659

305595
type: LocalParameter
value: 0.0

305594
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value: 0.0

305593
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value: 999999.0

305592
type: LocalParameter
value: 0.0

718881
type: SpeciesReference
stoichiometry: 1.0
species: 302654

302654
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Hydrogen peroxide_H2O2

718893
type: SpeciesReference
stoichiometry: 1.0
species: 302733

718869
type: SpeciesReference
stoichiometry: 2.0
species: 302735

302735
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Superoxide anion_O2

303067
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Succinate_C4H4O4

302579
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Dimethylallyl diphosphate_C5H9O7P2

303286
type: Reaction
kinetic law: 703461
product: 703449
reactant: 703436
notes: Abbreviation: R_EX_cys_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : cys-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Cysteine exchange

304362
type: LocalParameter
value: 0.0

304361
type: LocalParameter
value: 0.0

304360
type: LocalParameter
value: 999999.0

304359
type: LocalParameter
value: 0.0

703449
type: SpeciesReference
stoichiometry: 1.0
species: 303014

303014
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Cysteine_C3H7NO2S

703436
type: SpeciesReference
stoichiometry: 1.0
species: 302543

302543
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Cysteine_C3H7NO2S

302506
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Alanine_C3H7NO2

303774
type: Reaction
product: 720402
notes: Abbreviation: R_TRDR Synonyms: _0 EC Number: 1.8.1.9 SUBSYSTEM: Oxidative Phosphorylation Equation: [c] : h + nadph + trdox --> nadp + trdrd Confidence Level: 2 genes: LOCUS:BLBBGE_045#ABBREVIATION:trxB#ECNUMBERS:1.8.1.9# proteins: NAME:Thioredoxin reductase#ABBREVIATION:TrxB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_045)
reactant: 720366
name: thioredoxin reductase (NADPH)
product: 720390
fast: false
reversible: false
reactant: 720378
reactant: 720354
kinetic law: 720415

720402
type: SpeciesReference
stoichiometry: 1.0
species: 302949

720366
type: SpeciesReference
stoichiometry: 1.0
species: 302724

720390
type: SpeciesReference
stoichiometry: 1.0
species: 302723

720378
type: SpeciesReference
stoichiometry: 1.0
species: 302948

720354
type: SpeciesReference
stoichiometry: 1.0
species: 302659

305703
type: LocalParameter
value: 0.0

305701
type: LocalParameter
value: 0.0

305700
type: LocalParameter
value: 999999.0

305698
type: LocalParameter
value: 0.0

303615
type: Reaction
kinetic law: 713395
product: 713370
reactant: 713346
fast: false
product: 713382
notes: Abbreviation: R_NTPTP2 Synonyms: _0 EC Number: 3.1.5.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : gtp + h2o --> gsn + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_612#ABBREVIATION:dgt#ECNUMBERS:3.1.5.1# proteins: NAME:putative transmembrane HD family protein#ABBREVIATION:Dgt# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_612)
name: Nucleoside triphosphate tripolyhydrolase
reactant: 713358
reversible: false

305186
type: LocalParameter
value: 0.0

305185
type: LocalParameter
value: 0.0

305184
type: LocalParameter
value: 999999.0

305183
type: LocalParameter
value: 0.0

713370
type: SpeciesReference
stoichiometry: 1.0
species: 302650

302650
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Guanosine_C10H13N5O5

713346
type: SpeciesReference
stoichiometry: 1.0
species: 302651

713382
type: SpeciesReference
stoichiometry: 1.0
species: 302865

713358
type: SpeciesReference
stoichiometry: 1.0
species: 302655

302697
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Malonyl-[acyl-carrier protein]_C14H22N2O10PRS

302444
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Methyl-2-oxobutanoate_C5H7O3

303642
type: Reaction
reversible: false
reactant: 714239
fast: false
name: pyruvate dehydrogenase
product: 714251
kinetic law: 714287
notes: Abbreviation: R_PDH Synonyms: _0 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : coa + nad + pyr --> accoa + co2 + nadh Confidence Level: 2 genes: LOCUS:BLBBGE_099#ABBREVIATION:pdhA#ECNUMBERS:1.2.4.1# LOCUS:BLBBGE_098#ABBREVIATION:aceF#ECNUMBERS:2.3.1.12# LOCUS:BLBBGE_147#ABBREVIATION:lpd#ECNUMBERS:1.8.1.4# LOCUS:BLBBGE_446#ABBREVIATION:pdhB#ECNUMBERS:1.2.4.1# proteins: NAME:pyruvate dehydrogenase E1 component subunit beta#ABBREVIATION:PdhB# NAME:dihydrolipoamide dehydrogenase#ABBREVIATION:LpdA# NAME:Pyruvate dehydrogenase, F#ABBREVIATION:AceF# NAME:pyruvate dehydrogenase E1 component subunit alpha#ABBREVIATION:PdhA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_099) and (BLBBGE_098) and (BLBBGE_147) and (BLBBGE_446)
reactant: 714215
product: 714263
product: 714275
reactant: 714227

714239
type: SpeciesReference
stoichiometry: 1.0
species: 302893

714251
type: SpeciesReference
stoichiometry: 1.0
species: 302479

302479
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Acetyl-CoA_C23H34N7O17P3S

305246
type: LocalParameter
value: 0.0

305245
type: LocalParameter
value: 0.0

305244
type: LocalParameter
value: 999999.0

305243
type: LocalParameter
value: 0.0

714215
type: SpeciesReference
stoichiometry: 1.0
species: 302538

714263
type: SpeciesReference
stoichiometry: 1.0
species: 302536

714275
type: SpeciesReference
stoichiometry: 1.0
species: 302720

714227
type: SpeciesReference
stoichiometry: 1.0
species: 302719

303806
type: Reaction
product: 722094
product: 722118
name: uridine kinase (GTP:Uridine)
kinetic law: 722130
notes: Abbreviation: R_URIK2 Synonyms: _0 EC Number: 2.7.1.48 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : gtp + uri --> gdp + h + ump Confidence Level: 2 genes: LOCUS:BLBBGE_535#ABBREVIATION:udk#ECNUMBERS:2.7.1.48# proteins: NAME:uridine/cytidine kinase#ABBREVIATION:Udk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_535)
reactant: 722082
fast: false
reversible: false
reactant: 722070
product: 722106

722094
type: SpeciesReference
stoichiometry: 1.0
species: 302626

722118
type: SpeciesReference
stoichiometry: 1.0
species: 302980

305817
type: LocalParameter
value: 0.0

305816
type: LocalParameter
value: 0.0

305815
type: LocalParameter
value: 999999.0

305814
type: LocalParameter
value: 0.0

722082
type: SpeciesReference
stoichiometry: 1.0
species: 302989

722070
type: SpeciesReference
stoichiometry: 1.0
species: 302651

722106
type: SpeciesReference
stoichiometry: 1.0
species: 302659

302913
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-Succinyl-LL-2,6-diaminoheptanedioate_C11H16N2O7

303426
type: Reaction
kinetic law: 706919
reactant: 706835
name: GMP synthase
reversible: false
reactant: 706847
product: 706883
product: 706895
product: 706871
reactant: 706823
reactant: 706811
product: 706859
product: 706907
fast: false
notes: Abbreviation: R_GMPS2 Synonyms: _0 EC Number: 6.3.5.2 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : atp + gln-L + h2o + xmp --> amp + glu-L + gmp + (2) h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_478#ABBREVIATION:guaA#ECNUMBERS:6.3.5.2,-!-,6.3.4.1# proteins: NAME:GMP synthase#ABBREVIATION:GuaA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_478)

304671
type: LocalParameter
value: 0.0

304670
type: LocalParameter
value: 0.0

304669
type: LocalParameter
value: 999999.0

304667
type: LocalParameter
value: 0.0

706835
type: SpeciesReference
stoichiometry: 1.0
species: 302655

706847
type: SpeciesReference
stoichiometry: 1.0
species: 302998

706883
type: SpeciesReference
stoichiometry: 1.0
species: 302648

706895
type: SpeciesReference
stoichiometry: 2.0
species: 302659

706871
type: SpeciesReference
stoichiometry: 1.0
species: 302633

706823
type: SpeciesReference
stoichiometry: 1.0
species: 302628

706811
type: SpeciesReference
stoichiometry: 1.0
species: 302526

706859
type: SpeciesReference
stoichiometry: 1.0
species: 302511

706907
type: SpeciesReference
stoichiometry: 1.0
species: 302865

302478
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Acetyl-ACP_C13H23N2O8PRS

303679
type: Reaction
product: 715478
product: 715466
notes: Abbreviation: R_PPNCL2 Synonyms: _0 EC Number: 6.3.2.5 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 4ppan + ctp + cys-L --> 4ppcys + cmp + h + ppi Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 715429
product: 715454
kinetic law: 715502
name: phosphopantothenate-cysteine ligase
reversible: false
fast: false
reactant: 715441
product: 715490
reactant: 715417

715478
type: SpeciesReference
stoichiometry: 1.0
species: 302659

715466
type: SpeciesReference
stoichiometry: 1.0
species: 302534

715429
type: SpeciesReference
stoichiometry: 1.0
species: 302541

715454
type: SpeciesReference
stoichiometry: 1.0
species: 302459

302459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-((R)-4-Phosphopantothenoyl)-L-cysteine_C12H20N2O9PS

305346
type: LocalParameter
value: 0.0

305345
type: LocalParameter
value: 0.0

305344
type: LocalParameter
value: 999999.0

305343
type: LocalParameter
value: 0.0

715441
type: SpeciesReference
stoichiometry: 1.0
species: 302542

715490
type: SpeciesReference
stoichiometry: 1.0
species: 302865

715417
type: SpeciesReference
stoichiometry: 1.0
species: 302458

303732
type: Reaction
kinetic law: 718082
product: 718070
reactant: 718058
notes: Abbreviation: R_RPI Synonyms: _0 EC Number: 5.3.1.6 SUBSYSTEM: Pentose Phosphate Pathway Equation: [c] : r5p <==> ru5p-D Confidence Level: 2 SMP genes: LOCUS:BLBBGE_295#ABBREVIATION:rpiB#ECNUMBERS:5.3.1.6,-!-,5.3.1.-# proteins: NAME:ribose-5-phosphate isomerase B#ABBREVIATION:RpiB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_295)
fast: false
reversible: true
name: ribose-5-phosphate isomerase

305535
type: LocalParameter
value: 0.0

305534
type: LocalParameter
value: 0.0

305533
type: LocalParameter
value: 999999.0

305532
type: LocalParameter
value: -999999.0

718070
type: SpeciesReference
stoichiometry: 1.0
species: 302900

302900
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Ribulose 5-phosphate_C5H9O8P

718058
type: SpeciesReference
stoichiometry: 1.0
species: 302898

302427
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Oxobutanoate_C4H5O3

303177
type: Reaction
reactant: 699718
reactant: 699694
product: 699778
kinetic law: 699790
product: 699754
product: 699730
reactant: 699706
name: carbamoyl-phosphate synthase (glutamine-hydrolysing)
fast: false
reversible: false
reactant: 699681
product: 699766
product: 699742
notes: Abbreviation: R_CBPS Synonyms: _0 EC Number: 6.3.5.5 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : (2) atp + gln-L + h2o + hco3 --> (2) adp + cbp + glu-L + (2) h + pi Confidence Level: 2 genes: LOCUS:BLBBGE_316#ABBREVIATION:carA#ECNUMBERS:6.3.5.5# LOCUS:BLBBGE_317#ABBREVIATION:carB#ECNUMBERS:6.3.5.5# proteins: NAME:carbamoyl-phosphate synthetase#ABBREVIATION:Car# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_316 and BLBBGE_317)

699718
type: SpeciesReference
stoichiometry: 1.0
species: 302662

699694
type: SpeciesReference
stoichiometry: 1.0
species: 302628

699778
type: SpeciesReference
stoichiometry: 1.0
species: 302853

304098
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value: 0.0

304097
type: LocalParameter
value: 0.0

304096
type: LocalParameter
value: 999999.0

304095
type: LocalParameter
value: 0.0

699754
type: SpeciesReference
stoichiometry: 1.0
species: 302633

699730
type: SpeciesReference
stoichiometry: 2.0
species: 302493

699706
type: SpeciesReference
stoichiometry: 1.0
species: 302655

699681
type: SpeciesReference
stoichiometry: 2.0
species: 302526

699766
type: SpeciesReference
stoichiometry: 2.0
species: 302659

699742
type: SpeciesReference
stoichiometry: 1.0
species: 302527

303691
type: Reaction
kinetic law: 715851
product: 715839
reactant: 715827
notes: Abbreviation: R_PRAIi Synonyms: _0 EC Number: 5.3.1.24 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : pran --> 2cpr5p Confidence Level: 2 JLR- added irreversible form of PRAI genes: LOCUS:BLBBGE_425#ABBREVIATION:trpFB#ECNUMBERS:5.3.1.24,-!-,4.1.1.48# proteins: NAME:Phosphoribosyl anthranilate isomerase#ABBREVIATION:TrpFB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_425)
fast: false
reversible: false
name: phosphoribosylanthranilate isomerase (irreversible)

305369
type: LocalParameter
value: 0.0

305367
type: LocalParameter
value: 0.0

305366
type: LocalParameter
value: 999999.0

305364
type: LocalParameter
value: 0.0

715839
type: SpeciesReference
stoichiometry: 1.0
species: 302420

302420
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate_C12H13NO9P

715827
type: SpeciesReference
stoichiometry: 1.0
species: 302869

302869
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-(5-Phospho-D-ribosyl)anthranilate_C12H13NO9P

303230
type: Reaction
name: dihydrodipicolinate synthase
product: 701708
kinetic law: 701720
product: 701684
reactant: 701672
reversible: false
reactant: 701660
fast: false
notes: Abbreviation: R_DHDPS Synonyms: _0 EC Number: 4.2.1.52 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : aspsa + pyr --> 23dhdp + h + (2) h2o Confidence Level: 2 genes: LOCUS:BLBBGE_210#ABBREVIATION:dapA#ECNUMBERS:4.2.1.52# proteins: NAME:Dihydrodipicolinate synthetase#ABBREVIATION:DapA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_210)
product: 701696

701708
type: SpeciesReference
stoichiometry: 2.0
species: 302655

304226
type: LocalParameter
value: 0.0

304225
type: LocalParameter
value: 0.0

304224
type: LocalParameter
value: 999999.0

304223
type: LocalParameter
value: 0.0

701684
type: SpeciesReference
stoichiometry: 1.0
species: 302410

302410
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2,3-Dihydrodipicolinate_C7H5NO4

701672
type: SpeciesReference
stoichiometry: 1.0
species: 302893

701660
type: SpeciesReference
stoichiometry: 1.0
species: 302524

302524
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Aspartate 4-semialdehyde_C4H7NO3

701696
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303483
type: Reaction
notes: Abbreviation: R_IPPS Synonyms: _0 EC Number: 4.1.3.12 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 3mob + accoa + h2o --> 3c3hmp + coa + h Confidence Level: 2 genes: LOCUS:BLBBGE_067#ABBREVIATION:leuA#ECNUMBERS:4.1.3.12# proteins: NAME:Isopropylmalate synthase#ABBREVIATION:LeuA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_067)
product: 708820
name: _2-isopropylmalate synthase
reactant: 708770
product: 708795
reactant: 708758
kinetic law: 708832
product: 708808
fast: false
reactant: 708783
reversible: false

708820
type: SpeciesReference
stoichiometry: 1.0
species: 302659

708770
type: SpeciesReference
stoichiometry: 1.0
species: 302479

708795
type: SpeciesReference
stoichiometry: 1.0
species: 302436

302436
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Carboxy-3-hydroxy-4-methylpentanoate_C7H10O5

708758
type: SpeciesReference
stoichiometry: 1.0
species: 302444

304795
type: LocalParameter
value: 0.0

304794
type: LocalParameter
value: 0.0

304793
type: LocalParameter
value: 999999.0

304792
type: LocalParameter
value: 0.0

708808
type: SpeciesReference
stoichiometry: 1.0
species: 302538

708783
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303782
type: Reaction
notes: Abbreviation: R_TYRt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h[e] + tyr-L[e] <==> h[c] + tyr-L[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
product: 720775
reversible: true
fast: false
product: 720787
reactant: 720751
reactant: 720763
kinetic law: 720799
name: L-tyrosine reversible transport via proton symport

720775
type: SpeciesReference
stoichiometry: 1.0
species: 302659

720787
type: SpeciesReference
stoichiometry: 1.0
species: 302954

720751
type: SpeciesReference
stoichiometry: 1.0
species: 302660

720763
type: SpeciesReference
stoichiometry: 1.0
species: 302955

302955
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Tyrosine_C9H11NO3

305730
type: LocalParameter
value: 0.0

305729
type: LocalParameter
value: 0.0

305728
type: LocalParameter
value: 999999.0

305727
type: LocalParameter
value: -999999.0

303063
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Serine_C3H7NO3

302575
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Dihydropteroate_C14H13N6O3

303113
type: Reaction
product: 696264
product: 696252
notes: Abbreviation: R_ADSS Synonyms: _0 EC Number: 6.3.4.4 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : asp-L + gtp + imp --> dcamp + gdp + (2) h + pi Confidence Level: 2 genes: LOCUS:BLBBGE_488#ABBREVIATION:purA#ECNUMBERS:6.3.4.4# proteins: NAME:Adenylosuccinate synthetase#ABBREVIATION:PurA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_488)
name: adenylosuccinate synthase
reactant: 696204
kinetic law: 696276
reversible: false
reactant: 696216
product: 696240
reactant: 696192
product: 696228
fast: false

696264
type: SpeciesReference
stoichiometry: 1.0
species: 302853

696252
type: SpeciesReference
stoichiometry: 2.0
species: 302659

696204
type: SpeciesReference
stoichiometry: 1.0
species: 302651

303920
type: LocalParameter
value: 0.0

303919
type: LocalParameter
value: 0.0

303918
type: LocalParameter
value: 999999.0

303917
type: LocalParameter
value: 0.0

696216
type: SpeciesReference
stoichiometry: 1.0
species: 302683

696240
type: SpeciesReference
stoichiometry: 1.0
species: 302626

696192
type: SpeciesReference
stoichiometry: 1.0
species: 302522

696228
type: SpeciesReference
stoichiometry: 1.0
species: 302554

302554
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N6-(1,2-Dicarboxyethyl)-AMP_C14H14N5O11P

303650
type: Reaction
kinetic law: 714577
product: 714565
reactant: 714553
notes: Abbreviation: R_PGAMT Synonyms: _0 EC Number: 5.4.2.10 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : gam1p <==> gam6p Confidence Level: 2 involved in the pathway for bacterial cell-wall peptidoglycan and lipopolysaccharide biosyntheses, being an essential step in the pathway for UDP-N-acetylglucosamine biosynthesis. genes: LOCUS:BLBBGE_157#ABBREVIATION:manB#ECNUMBERS:5.4.2.10# proteins: NAME:phosphoglucomutase/phosphomannomutase family protein#ABBREVIATION:manB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_157)
fast: false
reversible: true
name: phosphoglucosamine mutase

305268
type: LocalParameter
value: 0.0

305267
type: LocalParameter
value: 0.0

305266
type: LocalParameter
value: 999999.0

305265
type: LocalParameter
value: -999999.0

714565
type: SpeciesReference
stoichiometry: 1.0
species: 302622

302622
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Glucosamine 6-phosphate_C6H13NO8P

714553
type: SpeciesReference
stoichiometry: 1.0
species: 302621

302621
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Glucosamine 1-phosphate_C6H13NO8P

302532
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Citrate_C6H5O7

303046
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Methionine_C5H11NO2S

303435
type: Reaction
kinetic law: 707232
product: 707220
reactant: 707208
notes: Abbreviation: R_H2Ot Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h2o[c] <==> h2o[e] Confidence Level: 1 renamed from H20t5 to H2Ot NCD genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: H2O transport via diffusion

304691
type: LocalParameter
value: 0.0

304690
type: LocalParameter
value: 0.0

304689
type: LocalParameter
value: 999999.0

304688
type: LocalParameter
value: -999999.0

707220
type: SpeciesReference
stoichiometry: 1.0
species: 302655

707208
type: SpeciesReference
stoichiometry: 1.0
species: 302656

302656
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: H2O_H2O

303475
type: Reaction
kinetic law: 708577
product: 708565
reactant: 708553
notes: Abbreviation: R_IPDDIi Synonyms: _0 EC Number: 5.3.3.2 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : ipdp <==> dmpp Confidence Level: 2 JLR- added irreversible form of IPDDI genes: LOCUS:BLBBGE_190#ABBREVIATION:idi#ECNUMBERS:5.3.3.2# proteins: NAME:isopentenyl diphosphate isomerase#ABBREVIATION:Idi# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_190)
fast: false
reversible: true
name: isopentenyl-diphosphate D-isomerase

304777
type: LocalParameter
value: 0.0

304776
type: LocalParameter
value: 0.0

304775
type: LocalParameter
value: 999999.0

304774
type: LocalParameter
value: -999999.0

708565
type: SpeciesReference
stoichiometry: 1.0
species: 302579

708553
type: SpeciesReference
stoichiometry: 1.0
species: 302687

303088
type: Reaction
kinetic law: 695311
product: 695299
reactant: 695287
notes: Abbreviation: R_ACONT Synonyms: _0 EC Number: 4.2.1.3 SUBSYSTEM: Citric Acid Cycle Equation: [c] : cit <==> icit Confidence Level: 2 SMP genes: LOCUS:BLBBGE_017#ABBREVIATION:acnA#ECNUMBERS:4.2.1.3# proteins: NAME:aconitase A#ABBREVIATION:AcnA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_017)
fast: false
reversible: true
name: aconitase

303850
type: LocalParameter
value: 0.0

303849
type: LocalParameter
value: 0.0

303848
type: LocalParameter
value: 999999.0

303847
type: LocalParameter
value: -999999.0

695299
type: SpeciesReference
stoichiometry: 1.0
species: 302676

302676
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Isocitrate_C6H5O7

695287
type: SpeciesReference
stoichiometry: 1.0
species: 302532

303025
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Glutamate_C5H8NO4

303181
type: Reaction
kinetic law: 699875
product: 699863
product: 699851
reactant: 699839
notes: Abbreviation: R_CHORS Synonyms: _0 EC Number: 4.2.3.5 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : 3psme --> chor + pi Confidence Level: 2 Previously EC 4.6.1.4. Now EC 4.2.3.5 genes: LOCUS:BLBBGE_185#ABBREVIATION:aroC#ECNUMBERS:4.2.3.5# proteins: NAME:Chorismate synthase#ABBREVIATION:AroC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_185)
fast: false
reversible: false
name: chorismate synthase

304106
type: LocalParameter
value: 0.0

304105
type: LocalParameter
value: 0.0

304104
type: LocalParameter
value: 999999.0

304103
type: LocalParameter
value: 0.0

699863
type: SpeciesReference
stoichiometry: 1.0
species: 302853

699851
type: SpeciesReference
stoichiometry: 1.0
species: 302531

699839
type: SpeciesReference
stoichiometry: 1.0
species: 302449

302449
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-O-(1-Carboxyvinyl)-3-phosphoshikimate_C10H9O10P

303494
type: Reaction
product: 709219
reactant: 709183
kinetic law: 709255
product: 709243
product: 709231
fast: false
notes: Abbreviation: R_KAS16 Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : ddcaACP + (2) h + malACP + nadph --> 3hmrsACP + ACP + co2 + nadp Confidence Level: 2 JLR- takes C12:0-ACP fatty acid part way through the elongation cycle. genes: LOCUS:BLBBGE_057#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100# LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.179# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_079) and (BLBBGE_057)
reactant: 709171
product: 709207
reversible: false
name: _3-hydroxy-myristoyl-ACP synthesis
reactant: 709195
reactant: 709159

709219
type: SpeciesReference
stoichiometry: 1.0
species: 302487

709183
type: SpeciesReference
stoichiometry: 1.0
species: 302697

304817
type: LocalParameter
value: 0.0

304816
type: LocalParameter
value: 0.0

304815
type: LocalParameter
value: 999999.0

304814
type: LocalParameter
value: 0.0

709243
type: SpeciesReference
stoichiometry: 1.0
species: 302723

709231
type: SpeciesReference
stoichiometry: 1.0
species: 302536

709171
type: SpeciesReference
stoichiometry: 2.0
species: 302659

709207
type: SpeciesReference
stoichiometry: 1.0
species: 302441

302441
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]_C25H47N2O9PRS

709195
type: SpeciesReference
stoichiometry: 1.0
species: 302724

709159
type: SpeciesReference
stoichiometry: 1.0
species: 302560

302560
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Dodecanoyl-ACP (n-C12:0ACP)_C23H43N2O8PRS

303793
type: Reaction
notes: Abbreviation: R_UAPGR Synonyms: _0 EC Number: 1.1.1.158 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : h + nadph + uaccg --> nadp + uamr Confidence Level: 2 genes: LOCUS:BLBBGE_376#ABBREVIATION:murB#ECNUMBERS:1.1.1.158# proteins: NAME:UDP-N-acetylenolpyruvoylglycosamine reductase#ABBREVIATION:MurB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_376)
reversible: false
fast: false
product: 721464
reactant: 721440
reactant: 721452
name: UDP-N-acetylenolpyruvoylglucosamine reductase
reactant: 721428
product: 721476
kinetic law: 721488

721464
type: SpeciesReference
stoichiometry: 1.0
species: 302723

721440
type: SpeciesReference
stoichiometry: 1.0
species: 302724

721452
type: SpeciesReference
stoichiometry: 1.0
species: 302963

721428
type: SpeciesReference
stoichiometry: 1.0
species: 302659

721476
type: SpeciesReference
stoichiometry: 1.0
species: 302970

302970
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: UDP-N-acetylmuramate_C20H28N3O19P2

305773
type: LocalParameter
value: 0.0

305771
type: LocalParameter
value: 0.0

305769
type: LocalParameter
value: 999999.0

305767
type: LocalParameter
value: 0.0

302423
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Demethylmenaquinol 8_C50H72O2

303008
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Arginine_C6H15N4O2

303256
type: Reaction
product: 702603
product: 702590
kinetic law: 702615
product: 702578
fast: false
notes: Abbreviation: R_DPCOAK Synonyms: _0 EC Number: 2.7.1.24 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + dpcoa --> adp + coa + h Confidence Level: 2 genes: LOCUS:BLBBGE_196#ABBREVIATION:coaE#ECNUMBERS:2.7.1.24# proteins: NAME:dephospho-CoA kinase#ABBREVIATION:CoaE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_196)
reversible: false
reactant: 702554
reactant: 702566
name: dephospho-CoA kinase

702603
type: SpeciesReference
stoichiometry: 1.0
species: 302659

702590
type: SpeciesReference
stoichiometry: 1.0
species: 302538

304290
type: LocalParameter
value: 0.0

304289
type: LocalParameter
value: 0.0

304288
type: LocalParameter
value: 999999.0

304286
type: LocalParameter
value: 0.0

702578
type: SpeciesReference
stoichiometry: 1.0
species: 302493

702554
type: SpeciesReference
stoichiometry: 1.0
species: 302526

702566
type: SpeciesReference
stoichiometry: 1.0
species: 302581

302581
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Dephospho-CoA_C21H33N7O13P2S

303643
type: Reaction
product: 714335
name: pyridoxine 5'-phosphate oxidase
reactant: 714311
product: 714323
kinetic law: 714347
reversible: false
notes: Abbreviation: R_PDX5PO Synonyms: _0 EC Number: 1.4.3.5 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : o2 + pdx5p --> h2o2 + pydx5p Confidence Level: 2 NCD genes: LOCUS:BLBBGE_050#ABBREVIATION:pdxH#ECNUMBERS:1.4.3.5# proteins: NAME:Pyridoxine 5-phosphate oxidase#ABBREVIATION:PdxH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_050)
fast: false
reactant: 714299

714335
type: SpeciesReference
stoichiometry: 1.0
species: 302889

714311
type: SpeciesReference
stoichiometry: 1.0
species: 302758

302758
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Pyridoxine 5'-phosphate_C8H10NO6P

714323
type: SpeciesReference
stoichiometry: 1.0
species: 302654

305253
type: LocalParameter
value: 0.0

305251
type: LocalParameter
value: 0.0

305250
type: LocalParameter
value: 999999.0

305248
type: LocalParameter
value: 0.0

714299
type: SpeciesReference
stoichiometry: 1.0
species: 302733

303534
type: Reaction
reactant: 710634
notes: Abbreviation: R_NADH10 Synonyms: _0 EC Number: 1.6.5.3 SUBSYSTEM: Oxidative Phosphorylation Equation: [c] : h + mqn8 + nadh --> mql8 + nad Confidence Level: 2 JLR genes: LOCUS:BLBBGE_193#ABBREVIATION:ndh#ECNUMBERS:1.16.1.-,-!-,1.6.99.3# proteins: NAME:NADH dehydrogenase II#ABBREVIATION:Ndh# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_193)
product: 710658
product: 710646
reactant: 710610
fast: false
name: NADH dehydrogenase (menaquinone-8 & 0 protons)
reactant: 710622
kinetic law: 710670
reversible: false

710634
type: SpeciesReference
stoichiometry: 1.0
species: 302720

710658
type: SpeciesReference
stoichiometry: 1.0
species: 302719

710646
type: SpeciesReference
stoichiometry: 1.0
species: 302709

710610
type: SpeciesReference
stoichiometry: 1.0
species: 302659

710622
type: SpeciesReference
stoichiometry: 1.0
species: 302710

304907
type: LocalParameter
value: 0.0

304906
type: LocalParameter
value: 0.0

304905
type: LocalParameter
value: 999999.0

304904
type: LocalParameter
value: 0.0

303446
type: Reaction
product: 707581
kinetic law: 707593
notes: Abbreviation: R_HMBS Synonyms: _0 EC Number: 4.3.1.8 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : h2o + (4) ppbng --> hmbil + (4) nh4 Confidence Level: 2 genes: LOCUS:BLBBGE_573#ABBREVIATION:hemC#ECNUMBERS:4.3.1.8# proteins: NAME:Hydroxymethylbilane synthase#ABBREVIATION:HemC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_573)
reactant: 707557
fast: false
reversible: false
name: hydroxymethylbilane synthase
reactant: 707545
product: 707569

707581
type: SpeciesReference
stoichiometry: 4.0
species: 302725

304713
type: LocalParameter
value: 0.0

304712
type: LocalParameter
value: 0.0

304711
type: LocalParameter
value: 999999.0

304710
type: LocalParameter
value: 0.0

707557
type: SpeciesReference
stoichiometry: 4.0
species: 302860

707545
type: SpeciesReference
stoichiometry: 1.0
species: 302655

707569
type: SpeciesReference
stoichiometry: 1.0
species: 302671

303699
type: Reaction
reactant: 716333
reversible: true
reactant: 716321
kinetic law: 716369
product: 716357
product: 716345
name: L-proline reversible transport via proton symport
notes: Abbreviation: R_PROt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h[e] + pro-L[e] <==> h[c] + pro-L[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false

716333
type: SpeciesReference
stoichiometry: 1.0
species: 302879

302879
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Proline_C5H9NO2

716321
type: SpeciesReference
stoichiometry: 1.0
species: 302660

305403
type: LocalParameter
value: 0.0

305402
type: LocalParameter
value: 0.0

305401
type: LocalParameter
value: 999999.0

305400
type: LocalParameter
value: -999999.0

716357
type: SpeciesReference
stoichiometry: 1.0
species: 302878

716345
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303260
type: Reaction
reactant: 702723
fast: false
reactant: 702711
product: 702747
product: 702735
name: dTMP kinase
kinetic law: 702759
reversible: true
notes: Abbreviation: R_DTMPK Synonyms: _0 EC Number: 2.7.4.9 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dtmp <==> adp + dtdp Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:

702723
type: SpeciesReference
stoichiometry: 1.0
species: 302584

302584
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dTMP_C10H13N2O8P

702711
type: SpeciesReference
stoichiometry: 1.0
species: 302526

702747
type: SpeciesReference
stoichiometry: 1.0
species: 302583

302583
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dTDP_C10H13N2O11P2

702735
type: SpeciesReference
stoichiometry: 1.0
species: 302493

304298
type: LocalParameter
value: 0.0

304297
type: LocalParameter
value: 0.0

304296
type: LocalParameter
value: 999999.0

304295
type: LocalParameter
value: -999999.0

303042
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Lysine_C6H15N2O2

303595
type: Reaction
reactant: 712644
notes: Abbreviation: R_NTD9 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : gmp + h2o --> gsn + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
reversible: false
kinetic law: 712692
reactant: 712656
name: _5'-nucleotidase (GMP)
product: 712680
product: 712668
fast: false

712644
type: SpeciesReference
stoichiometry: 1.0
species: 302648

305045
type: LocalParameter
value: 0.0

305044
type: LocalParameter
value: 0.0

305043
type: LocalParameter
value: 999999.0

305042
type: LocalParameter
value: 0.0

712656
type: SpeciesReference
stoichiometry: 1.0
species: 302655

712680
type: SpeciesReference
stoichiometry: 1.0
species: 302853

712668
type: SpeciesReference
stoichiometry: 1.0
species: 302650

302672
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Homoserine_C4H9NO3

303486
type: Reaction
reactant: 708844
reactant: 708856
kinetic law: 708904
fast: false
reactant: 708868
product: 708892
name: acetohydroxy acid isomeroreductase
notes: Abbreviation: R_KARA1i Synonyms: _0 EC Number: 1.1.1.86 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : alac-S + h + nadph --> 23dhmb + nadp Confidence Level: 2 used to be named AHAI; renamed for consistency; irreversible form of KARA1i - NCD genes: LOCUS:BLBBGE_554#ABBREVIATION:ilvC#ECNUMBERS:1.1.1.86# proteins: NAME:acetohydroxy acid isomeroreductase#ABBREVIATION:IlvC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_554)
product: 708880
reversible: false

708844
type: SpeciesReference
stoichiometry: 1.0
species: 302508

708856
type: SpeciesReference
stoichiometry: 1.0
species: 302659

304799
type: LocalParameter
value: 0.0

304798
type: LocalParameter
value: 0.0

304797
type: LocalParameter
value: 999999.0

304796
type: LocalParameter
value: 0.0

708868
type: SpeciesReference
stoichiometry: 1.0
species: 302724

708892
type: SpeciesReference
stoichiometry: 1.0
species: 302723

708880
type: SpeciesReference
stoichiometry: 1.0
species: 302411

302411
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (R)-2,3-Dihydroxy-3-methylbutanoate_C5H9O4

303767
type: Reaction
name: transketolase
fast: false
product: 720017
kinetic law: 720042
reversible: true
reactant: 720005
notes: Abbreviation: R_TKT2 Synonyms: _0 EC Number: 2.2.1.1 SUBSYSTEM: Pentose Phosphate Pathway Equation: [c] : e4p + xu5p-D <==> f6p + g3p Confidence Level: 2 SMP Two reactions for transketolase: TKT1 and TKT2 genes: LOCUS:BLBBGE_403#ABBREVIATION:tkt#ECNUMBERS:2.2.1.1# LOCUS:BLBBGE_404#ABBREVIATION:tkt#ECNUMBERS:2.2.1.1# proteins: NAME:transketolase N-terminal subunit#ABBREVIATION:Tkt# NAME:transketolase C-terminal subunit#ABBREVIATION:Tkt# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_403 and BLBBGE_404)
reactant: 719992
product: 720029

720017
type: SpeciesReference
stoichiometry: 1.0
species: 302597

302597
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Fructose 6-phosphate_C6H11O9P

305673
type: LocalParameter
value: 0.0

305671
type: LocalParameter
value: 0.0

305670
type: LocalParameter
value: 999999.0

305668
type: LocalParameter
value: -999999.0

720005
type: SpeciesReference
stoichiometry: 1.0
species: 303000

303000
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Xylulose 5-phosphate_C5H9O8P

719992
type: SpeciesReference
stoichiometry: 1.0
species: 302593

302593
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Erythrose 4-phosphate_C4H7O7P

720029
type: SpeciesReference
stoichiometry: 1.0
species: 302620

303265
type: Reaction
notes: Abbreviation: R_DUTPDP Synonyms: _0 EC Number: 3.6.1.23 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dutp + h2o --> dump + h + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_606#ABBREVIATION:dut#ECNUMBERS:3.6.1.23# LOCUS:BLBBGE_p003#ABBREVIATION:dut#ECNUMBERS:3.6.1.23# proteins: NAME:deoxyuridine 5'-triphosphate nucleotidohydrolase#ABBREVIATION:Dut# NAME:dUTP pyrophosphatase#ABBREVIATION:Dut# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_606) or (BLBBGE_p003)
reactant: 702904
kinetic law: 702966
name: dUTP diphosphatase
product: 702941
product: 702929
reactant: 702916
product: 702953
reversible: false
fast: false

702904
type: SpeciesReference
stoichiometry: 1.0
species: 302591

302591
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dUTP_C9H11N2O14P3

304312
type: LocalParameter
value: 0.0

304311
type: LocalParameter
value: 0.0

304310
type: LocalParameter
value: 999999.0

304309
type: LocalParameter
value: 0.0

702941
type: SpeciesReference
stoichiometry: 1.0
species: 302659

702929
type: SpeciesReference
stoichiometry: 1.0
species: 302588

702916
type: SpeciesReference
stoichiometry: 1.0
species: 302655

702953
type: SpeciesReference
stoichiometry: 1.0
species: 302865

303635
type: Reaction
name: phospho-N-acetylmuramoyl-pentapeptide-transferase (meso-2,6-diaminopimelate)
reversible: false
notes: Abbreviation: R_PAPPT3 Synonyms: _0 EC Number: 2.7.8.13 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : udcpp + ugmda --> uagmda + ump Confidence Level: 2 genes: LOCUS:BLBBGE_389#ABBREVIATION:mraY#ECNUMBERS:2.7.8.13# proteins: NAME:Phospho-N-acetylmuramoyl-pentapeptide transferase#ABBREVIATION:MraY# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_389)
reactant: 713975
fast: false
product: 713999
reactant: 713962
product: 713987
kinetic law: 714011

713975
type: SpeciesReference
stoichiometry: 1.0
species: 302979

302979
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405

713999
type: SpeciesReference
stoichiometry: 1.0
species: 302980

713962
type: SpeciesReference
stoichiometry: 1.0
species: 302974

302974
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Undecaprenyl phosphate_C55H89O4P

713987
type: SpeciesReference
stoichiometry: 1.0
species: 302965

302965
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405

305231
type: LocalParameter
value: 0.0

305230
type: LocalParameter
value: 0.0

305229
type: LocalParameter
value: 999999.0

305228
type: LocalParameter
value: 0.0

303587
type: Reaction
notes: Abbreviation: R_NTD5 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Sugar Metabolism Equation: [c] : dtmp + h2o --> pi + thymd Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 712425
reversible: false
product: 712437
fast: false
kinetic law: 712449
reactant: 712401
name: _5'-nucleotidase (dTMP)
reactant: 712413

712425
type: SpeciesReference
stoichiometry: 1.0
species: 302853

712437
type: SpeciesReference
stoichiometry: 1.0
species: 302945

302945
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Thymidine_C10H14N2O5

305027
type: LocalParameter
value: 0.0

305026
type: LocalParameter
value: 0.0

305025
type: LocalParameter
value: 999999.0

305024
type: LocalParameter
value: 0.0

712401
type: SpeciesReference
stoichiometry: 1.0
species: 302584

712413
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303055
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Phenylalanine_C9H11NO2

302567
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _7,8-Dihydrofolate_C19H19N7O6

303405
type: Reaction
kinetic law: 706184
reversible: false
product: 706135
product: 706147
fast: false
name: L-glutamine transport via ABC system
product: 706172
product: 706160
reactant: 706111
reactant: 706123
notes: Abbreviation: R_GLNabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + gln-L[e] + h2o[c] --> adp[c] + gln-L[c] + h[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 706099

304623
type: LocalParameter
value: 0.0

304622
type: LocalParameter
value: 0.0

304621
type: LocalParameter
value: 999999.0

304620
type: LocalParameter
value: 0.0

706135
type: SpeciesReference
stoichiometry: 1.0
species: 302493

706147
type: SpeciesReference
stoichiometry: 1.0
species: 302628

706172
type: SpeciesReference
stoichiometry: 1.0
species: 302853

706160
type: SpeciesReference
stoichiometry: 1.0
species: 302659

706111
type: SpeciesReference
stoichiometry: 1.0
species: 302629

302629
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Glutamine_C5H10N2O3

706123
type: SpeciesReference
stoichiometry: 1.0
species: 302655

706099
type: SpeciesReference
stoichiometry: 1.0
species: 302526

303160
type: Reaction
kinetic law: 698183
fast: false
reversible: false
name: ATP phosphoribosyltransferase
product: 698169
notes: Abbreviation: R_ATPPRT Synonyms: _0 EC Number: 2.4.2.17 SUBSYSTEM: Histidine Metabolism Equation: [c] : atp + prpp --> ppi + prbatp Confidence Level: 2 genes: LOCUS:BLBBGE_433#ABBREVIATION:hisG#ECNUMBERS:2.4.2.17# proteins: NAME:ATP phosphoribosyltransferase#ABBREVIATION:HisG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_433)
product: 698156
reactant: 698130
reactant: 698143

304050
type: LocalParameter
value: 0.0

304049
type: LocalParameter
value: 0.0

304048
type: LocalParameter
value: 999999.0

304047
type: LocalParameter
value: 0.0

698169
type: SpeciesReference
stoichiometry: 1.0
species: 302873

302873
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _1-(5-Phosphoribosyl)-ATP_C15H19N5O20P4

698156
type: SpeciesReference
stoichiometry: 1.0
species: 302865

698130
type: SpeciesReference
stoichiometry: 1.0
species: 302526

698143
type: SpeciesReference
stoichiometry: 1.0
species: 302880

303238
type: Reaction
kinetic law: 702011
product: 701999
product: 701987
reactant: 701975
notes: Abbreviation: R_DHNPA2 Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : dhnpt <==> 6hmhpt + gcald Confidence Level: 2 JLR- similar to DHNPA except the 'pterin product is different genes: LOCUS:BLBBGE_292#ABBREVIATION:folB#ECNUMBERS:4.1.2.25# proteins: NAME:dihydroneopterin aldolase#ABBREVIATION:FolB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_292)
fast: false
reversible: true
name: dihydroneopterin aldolase

304244
type: LocalParameter
value: 0.0

304243
type: LocalParameter
value: 0.0

304242
type: LocalParameter
value: 999999.0

304241
type: LocalParameter
value: -999999.0

701999
type: SpeciesReference
stoichiometry: 1.0
species: 302625

302625
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Glycolaldehyde_C2H4O2

701987
type: SpeciesReference
stoichiometry: 1.0
species: 302473

701975
type: SpeciesReference
stoichiometry: 1.0
species: 302570

303658
type: Reaction
reactant: 714769
fast: false
product: 714781
product: 714793
reversible: true
name: L-phenylalanine reversible transport via proton symport
kinetic law: 714805
notes: Abbreviation: R_PHEt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h[e] + phe-L[e] <==> h[c] + phe-L[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 714757

714769
type: SpeciesReference
stoichiometry: 1.0
species: 302765

714781
type: SpeciesReference
stoichiometry: 1.0
species: 302659

714793
type: SpeciesReference
stoichiometry: 1.0
species: 302764

305290
type: LocalParameter
value: 0.0

305288
type: LocalParameter
value: 0.0

305287
type: LocalParameter
value: 999999.0

305285
type: LocalParameter
value: -999999.0

714757
type: SpeciesReference
stoichiometry: 1.0
species: 302660

303257
type: Reaction
product: 702663
fast: false
kinetic law: 702699
reactant: 702627
name: diphosphomevalonate decarboxylase
product: 702687
reversible: false
notes: Abbreviation: R_DPMVDx Synonyms: _0 EC Number: 4.1.1.33 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : 5dpmev + atp --> adp + co2 + ipdp + pi Confidence Level: 2 genes: LOCUS:BLBBGE_357#ABBREVIATION:mvaD#ECNUMBERS:4.1.1.33# proteins: NAME:diphosphomevalonate decarboxylase#ABBREVIATION:MvaD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_357)
reactant: 702639
product: 702675
product: 702651

702663
type: SpeciesReference
stoichiometry: 1.0
species: 302536

304294
type: LocalParameter
value: 0.0

304293
type: LocalParameter
value: 0.0

304292
type: LocalParameter
value: 999999.0

304291
type: LocalParameter
value: 0.0

702627
type: SpeciesReference
stoichiometry: 1.0
species: 302466

302466
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (R)-5-Diphosphomevalonate_C6H10O10P2

702687
type: SpeciesReference
stoichiometry: 1.0
species: 302853

702639
type: SpeciesReference
stoichiometry: 1.0
species: 302526

702675
type: SpeciesReference
stoichiometry: 1.0
species: 302687

702651
type: SpeciesReference
stoichiometry: 1.0
species: 302493

302432
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate_C11H10O6

303711
type: Reaction
reactant: 716971
name: purine-nucleoside phosphorylase (Guanosine)
product: 716996
fast: false
reactant: 716959
kinetic law: 717008
notes: Abbreviation: R_PUNP3 Synonyms: _0 EC Number: 2.4.2.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : gsn + pi <==> gua + r1p Confidence Level: 2 Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase genes: LOCUS:BLBBGE_377#ABBREVIATION:pndA#ECNUMBERS:2.4.2.1# proteins: NAME:purine-nucleoside phosphorylase#ABBREVIATION:PndA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)
product: 716983
reversible: true

716971
type: SpeciesReference
stoichiometry: 1.0
species: 302853

716996
type: SpeciesReference
stoichiometry: 1.0
species: 302895

302895
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: alpha-D-Ribose 1-phosphate_C5H9O8P

716959
type: SpeciesReference
stoichiometry: 1.0
species: 302650

305452
type: LocalParameter
value: 0.0

305451
type: LocalParameter
value: 0.0

305450
type: LocalParameter
value: 999999.0

305449
type: LocalParameter
value: -999999.0

716983
type: SpeciesReference
stoichiometry: 1.0
species: 302652

303125
type: Reaction
kinetic law: 696820
product: 696808
reactant: 696784
fast: false
notes: Abbreviation: R_AKGt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: akg[e] + h[e] <==> akg[c] + h[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
name: _2-oxoglutarate reversible transport via symport
reversible: true
product: 696796
reactant: 696772

303958
type: LocalParameter
value: 0.0

303957
type: LocalParameter
value: 0.0

303956
type: LocalParameter
value: 999999.0

303955
type: LocalParameter
value: -999999.0

696808
type: SpeciesReference
stoichiometry: 1.0
species: 302659

696784
type: SpeciesReference
stoichiometry: 1.0
species: 302660

696796
type: SpeciesReference
stoichiometry: 1.0
species: 302500

696772
type: SpeciesReference
stoichiometry: 1.0
species: 302502

303726
type: Reaction
reactant: 717745
reactant: 717733
product: 717781
product: 717757
notes: Abbreviation: R_RNDR1 Synonyms: _0 EC Number: 1.17.4.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : adp + trdrd --> dadp + h2o + trdox Confidence Level: 2 genes: LOCUS:BLBBGE_310#ABBREVIATION:nrdA#ECNUMBERS:1.17.4.1# LOCUS:BLBBGE_p006#ABBREVIATION:nrdF#ECNUMBERS:1.17.4.1# proteins: NAME:ribonucleoside-diphosphate reductase subunit alpha#ABBREVIATION:NrdA# NAME:ribonucleotide-diphosphate reductase beta subunit#ABBREVIATION:NrdF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_310 and BLBBGE_p006)
product: 717769
kinetic law: 717793
reversible: false
fast: false
name: ribonucleoside-diphosphate reductase (ADP)

717745
type: SpeciesReference
stoichiometry: 1.0
species: 302949

717733
type: SpeciesReference
stoichiometry: 1.0
species: 302493

717781
type: SpeciesReference
stoichiometry: 1.0
species: 302948

717757
type: SpeciesReference
stoichiometry: 1.0
species: 302548

717769
type: SpeciesReference
stoichiometry: 1.0
species: 302655

305512
type: LocalParameter
value: 0.0

305511
type: LocalParameter
value: 0.0

305510
type: LocalParameter
value: 999999.0

305509
type: LocalParameter
value: 0.0

302415
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2,5-Diamino-6-(ribosylamino)-4-(3H)-pyrimidinone 5'-phosphate_C9H14N5O8P

303207
type: Reaction
reactant: 700873
kinetic law: 700909
reactant: 700849
reversible: false
product: 700897
notes: Abbreviation: R_DADA Synonyms: _0 EC Number: 3.5.4.4 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dad-2 + h + h2o --> din + nh4 Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
name: Deoxyadenosine deaminase
product: 700885
reactant: 700861
fast: false

700873
type: SpeciesReference
stoichiometry: 1.0
species: 302655

304170
type: LocalParameter
value: 0.0

304169
type: LocalParameter
value: 0.0

304168
type: LocalParameter
value: 999999.0

304166
type: LocalParameter
value: 0.0

700849
type: SpeciesReference
stoichiometry: 1.0
species: 302547

302547
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Deoxyadenosine_C10H13N5O3

700897
type: SpeciesReference
stoichiometry: 1.0
species: 302725

700885
type: SpeciesReference
stoichiometry: 1.0
species: 302576

700861
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303531
type: Reaction
reactant: 710550
kinetic law: 710598
product: 710586
reactant: 710538
name: NAD diphosphatase
fast: false
product: 710562
reversible: false
notes: Abbreviation: R_NADDP Synonyms: _0 EC Number: 3.6.1.22 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : h2o + nad --> amp + (2) h + nmn Confidence Level: 2 See also EC 3.6.1.9 genes: LOCUS:BLBBGE_333#ABBREVIATION:ligA#ECNUMBERS:6.5.1.2# proteins: NAME:DNA ligase#ABBREVIATION:Lig# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_333)
product: 710574

710550
type: SpeciesReference
stoichiometry: 1.0
species: 302719

304903
type: LocalParameter
value: 0.0

304902
type: LocalParameter
value: 0.0

304901
type: LocalParameter
value: 999999.0

304900
type: LocalParameter
value: 0.0

710586
type: SpeciesReference
stoichiometry: 1.0
species: 302730

710538
type: SpeciesReference
stoichiometry: 1.0
species: 302655

710562
type: SpeciesReference
stoichiometry: 1.0
species: 302511

710574
type: SpeciesReference
stoichiometry: 2.0
species: 302659

302894
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Pyruvate_C3H3O3

303189
type: Reaction
notes: Abbreviation: R_CSND Synonyms: _0 EC Number: 3.5.4.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : csn + h + h2o --> nh4 + ura Confidence Level: 2 JLR genes: LOCUS:BLBBGE_353#ABBREVIATION:codA#ECNUMBERS:3.5.4.1# proteins: NAME:cytosine deaminase#ABBREVIATION:CodA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_353)
product: 700115
name: Cytosine deaminase
fast: false
reactant: 700091
reactant: 700067
reversible: false
reactant: 700079
kinetic law: 700127
product: 700103

700115
type: SpeciesReference
stoichiometry: 1.0
species: 302984

700091
type: SpeciesReference
stoichiometry: 1.0
species: 302655

700067
type: SpeciesReference
stoichiometry: 1.0
species: 302539

700079
type: SpeciesReference
stoichiometry: 1.0
species: 302659

304124
type: LocalParameter
value: 0.0

304123
type: LocalParameter
value: 0.0

304122
type: LocalParameter
value: 999999.0

304121
type: LocalParameter
value: 0.0

700103
type: SpeciesReference
stoichiometry: 1.0
species: 302725

303215
type: Reaction
kinetic law: 701138
reactant: 701102
fast: false
product: 701126
product: 701114
reactant: 701078
reactant: 701090
notes: Abbreviation: R_DASYN_Bge Synonyms: _0 EC Number: 2.7.7.41 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : ctp + h + (0.02) pa_Bge --> (0.02) cdpdag_Bge + ppi Confidence Level: 2 tv genes: LOCUS:BLBBGE_224#ABBREVIATION:cdsA#ECNUMBERS:2.7.7.41# proteins: NAME:CDP-diglyceride synthetase#ABBREVIATION:CdsA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_224)
name: CDP-Diacylglycerol synthetase
reversible: false

304186
type: LocalParameter
value: 0.0

304185
type: LocalParameter
value: 0.0

304184
type: LocalParameter
value: 999999.0

304183
type: LocalParameter
value: 0.0

701102
type: SpeciesReference
stoichiometry: 0.02
species: 302749

701126
type: SpeciesReference
stoichiometry: 1.0
species: 302865

701114
type: SpeciesReference
stoichiometry: 0.02
species: 302529

302529
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: CDPdiacylglycerol (Blattabacterium Blattella germanica)_C2286H3998N150O750P100

701078
type: SpeciesReference
stoichiometry: 1.0
species: 302541

701090
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303670
type: Reaction
product: 715153
notes: Abbreviation: R_PNTOt4 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: na1[e] + pnto-R[e] --> na1[c] + pnto-R[c] Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
name: Pantothenate sodium symporter
reactant: 715129
kinetic law: 715177
reversible: false
fast: false
product: 715165
reactant: 715141

715153
type: SpeciesReference
stoichiometry: 1.0
species: 302713

302713
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Sodium_Na

715129
type: SpeciesReference
stoichiometry: 1.0
species: 302714

305320
type: LocalParameter
value: 0.0

305319
type: LocalParameter
value: 0.0

305318
type: LocalParameter
value: 999999.0

305317
type: LocalParameter
value: 0.0

715165
type: SpeciesReference
stoichiometry: 1.0
species: 302858

715141
type: SpeciesReference
stoichiometry: 1.0
species: 302859

302859
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: (R)-Pantothenate_C9H16NO5

303696
type: Reaction
product: 716213
fast: false
reactant: 716165
kinetic law: 716273
product: 716249
notes: Abbreviation: R_PRFGS Synonyms: _0 EC Number: 6.3.5.3 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : atp + fgam + gln-L + h2o --> adp + fpram + glu-L + h + pi Confidence Level: 2 genes: LOCUS:BLBBGE_486#ABBREVIATION:purL#ECNUMBERS:6.3.5.3# proteins: NAME:Phosphoribosylformylglycineamide synthetase#ABBREVIATION:PurL# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_486)
name: phosphoribosylformylglycinamidine synthase
product: 716261
reactant: 716177
product: 716225
reversible: false
product: 716237
reactant: 716189
reactant: 716201

716213
type: SpeciesReference
stoichiometry: 1.0
species: 302493

716165
type: SpeciesReference
stoichiometry: 1.0
species: 302526

305392
type: LocalParameter
value: 0.0

305391
type: LocalParameter
value: 0.0

305390
type: LocalParameter
value: 999999.0

305389
type: LocalParameter
value: 0.0

716249
type: SpeciesReference
stoichiometry: 1.0
species: 302659

716261
type: SpeciesReference
stoichiometry: 1.0
species: 302853

716177
type: SpeciesReference
stoichiometry: 1.0
species: 302605

302605
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide_C8H13N2O9P

716225
type: SpeciesReference
stoichiometry: 1.0
species: 302610

716237
type: SpeciesReference
stoichiometry: 1.0
species: 302633

716189
type: SpeciesReference
stoichiometry: 1.0
species: 302628

716201
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303495
type: Reaction
name: ketohexokinase
notes: Abbreviation: R_KHK Synonyms: _0 EC Number: 2.7.1.3 SUBSYSTEM: Fructose and Mannose Metabolism Equation: [c] : atp + fru --> adp + f1p + h Confidence Level: 2 genes: LOCUS:BLBBGE_008#ECNUMBERS:2.7.1.-# proteins: NAME:carbohydrate kinase citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_008)
reactant: 709279
product: 709315
kinetic law: 709327
fast: false
product: 709291
reactant: 709267
product: 709303
reversible: false

709279
type: SpeciesReference
stoichiometry: 1.0
species: 302526

709315
type: SpeciesReference
stoichiometry: 1.0
species: 302659

304823
type: LocalParameter
value: 0.0

304822
type: LocalParameter
value: 0.0

304821
type: LocalParameter
value: 999999.0

304819
type: LocalParameter
value: 0.0

709291
type: SpeciesReference
stoichiometry: 1.0
species: 302596

709267
type: SpeciesReference
stoichiometry: 1.0
species: 302614

302614
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Fructose_C6H12O6

709303
type: SpeciesReference
stoichiometry: 1.0
species: 302493

303794
type: Reaction
product: 721524
notes: Abbreviation: R_UDCPDP Synonyms: _0 EC Number: 3.6.1.27 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : h2o + udcpdp --> h + pi + udcpp Confidence Level: 2 genes: LOCUS:BLBBGE_362#ABBREVIATION:uppP#ECNUMBERS:3.6.1.27# proteins: NAME:undecaprenyl-diphosphatase#ABBREVIATION:UppP# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_362)
reversible: false
reactant: 721500
fast: false
kinetic law: 721560
reactant: 721512
product: 721536
product: 721548
name: undecaprenyl-diphosphatase

721524
type: SpeciesReference
stoichiometry: 1.0
species: 302659

721500
type: SpeciesReference
stoichiometry: 1.0
species: 302655

305777
type: LocalParameter
value: 0.0

305776
type: LocalParameter
value: 0.0

305775
type: LocalParameter
value: 999999.0

305774
type: LocalParameter
value: 0.0

721512
type: SpeciesReference
stoichiometry: 1.0
species: 302973

721536
type: SpeciesReference
stoichiometry: 1.0
species: 302853

721548
type: SpeciesReference
stoichiometry: 1.0
species: 302974

303051
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Ammonium_H4N

303662
type: Reaction
product: 714913
reactant: 714889
reversible: true
fast: false
notes: Abbreviation: R_PIt7 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: (3) na1[e] + pi[e] <==> (3) na1[c] + pi[c] Confidence Level: 2 NCD genes: LOCUS:BLBBGE_368#ABBREVIATION:pit# proteins: NAME:phosphate sodium symporter#ABBREVIATION:Pit# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_368)
kinetic law: 714925
product: 714901
reactant: 714877
name: phosphate transport in/out via three Na+ symporter

714913
type: SpeciesReference
stoichiometry: 1.0
species: 302853

714889
type: SpeciesReference
stoichiometry: 1.0
species: 302855

302855
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Phosphate_HO4P

305301
type: LocalParameter
value: 0.0

305299
type: LocalParameter
value: 0.0

305298
type: LocalParameter
value: 999999.0

305296
type: LocalParameter
value: -999999.0

714901
type: SpeciesReference
stoichiometry: 3.0
species: 302713

714877
type: SpeciesReference
stoichiometry: 3.0
species: 302714

303030
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Glycerol_C3H8O3

302546
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Cytidine_C9H13N3O5

303804
type: Reaction
reactant: 722022
notes: Abbreviation: R_URIDK2r Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dump <==> adp + dudp Confidence Level: 2 JLR- reversible form of URIDK2 genes: LOCUS:BLBBGE_120#ABBREVIATION:pyrH#ECNUMBERS:2.7.4.-# proteins: NAME:uridylate kinase#ABBREVIATION:PyrH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_120)
fast: false
reversible: true
reactant: 722009
name: uridylate kinase (dUMP)
product: 722046
kinetic law: 722058
product: 722034

722022
type: SpeciesReference
stoichiometry: 1.0
species: 302588

722009
type: SpeciesReference
stoichiometry: 1.0
species: 302526

722046
type: SpeciesReference
stoichiometry: 1.0
species: 302587

305813
type: LocalParameter
value: 0.0

305812
type: LocalParameter
value: 0.0

305811
type: LocalParameter
value: 999999.0

305810
type: LocalParameter
value: -999999.0

722034
type: SpeciesReference
stoichiometry: 1.0
species: 302493

303242
type: Reaction
kinetic law: 702108
product: 702096
reactant: 702084
notes: Abbreviation: R_dhorSt Synonyms: _0 Equation: dhor-S[e] <==> dhor-S[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: S-Dihydroorotate transporter

304252
type: LocalParameter
value: 0.0

304251
type: LocalParameter
value: 0.0

304250
type: LocalParameter
value: 999999.0

304249
type: LocalParameter
value: -999999.0

702096
type: SpeciesReference
stoichiometry: 1.0
species: 302571

702084
type: SpeciesReference
stoichiometry: 1.0
species: 302572

303268
type: Reaction
fast: false
reversible: false
notes: Abbreviation: R_DXPS Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : g3p + h + pyr --> co2 + dxyl5p Confidence Level: 1 EC 4.1.3.37 transferred to:EC 2.2.1.7NJ genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 703002
product: 703014
kinetic law: 703038
reactant: 702978
product: 703026
reactant: 702990
name: _1-deoxy-D-xylulose 5-phosphate synthase

703002
type: SpeciesReference
stoichiometry: 1.0
species: 302893

703014
type: SpeciesReference
stoichiometry: 1.0
species: 302536

304318
type: LocalParameter
value: 0.0

304317
type: LocalParameter
value: 0.0

304316
type: LocalParameter
value: 999999.0

304314
type: LocalParameter
value: 0.0

702978
type: SpeciesReference
stoichiometry: 1.0
species: 302620

703026
type: SpeciesReference
stoichiometry: 1.0
species: 302592

302592
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _1-deoxy-D-xylulose 5-phosphate_C5H9O7P

702990
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303737
type: Reaction
name: _2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
product: 718359
notes: Abbreviation: R_SEPHCHC Synonyms: _1 EC Number: 4.1.1.71 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : ichor + akg + (2) h --> co2 + 5ephchc Confidence Level: 2 JLR genes: LOCUS:BLBBGE_056#ABBREVIATION:menD#ECNUMBERS:4.1.1.71,-!-,2.2.1.9# proteins: NAME:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase#ABBREVIATION:MenD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_056)
product: 718371
reactant: 718335
fast: false
reactant: 718347
reversible: false
kinetic law: 718383
reactant: 718323

718359
type: SpeciesReference
stoichiometry: 1.0
species: 302536

718371
type: SpeciesReference
stoichiometry: 1.0
species: 302468

718335
type: SpeciesReference
stoichiometry: 1.0
species: 302500

718347
type: SpeciesReference
stoichiometry: 2.0
species: 302659

305554
type: LocalParameter
value: 0.0

305553
type: LocalParameter
value: 0.0

305552
type: LocalParameter
value: 999999.0

305551
type: LocalParameter
value: 0.0

718323
type: SpeciesReference
stoichiometry: 1.0
species: 302675

303730
type: Reaction
product: 717973
reversible: false
kinetic law: 718009
name: ribonucleoside-diphosphate reductase (UDP)
reactant: 717949
product: 717997
reactant: 717961
notes: Abbreviation: R_RNDR4 Synonyms: _0 EC Number: 1.17.4.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : trdrd + udp --> dudp + h2o + trdox Confidence Level: 2 genes: LOCUS:BLBBGE_310#ABBREVIATION:nrdA#ECNUMBERS:1.17.4.1# LOCUS:BLBBGE_p006#ABBREVIATION:nrdF#ECNUMBERS:1.17.4.1# proteins: NAME:ribonucleoside-diphosphate reductase subunit alpha#ABBREVIATION:NrdA# NAME:ribonucleotide-diphosphate reductase beta subunit#ABBREVIATION:NrdF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_310 and BLBBGE_p006)
product: 717985
fast: false

717973
type: SpeciesReference
stoichiometry: 1.0
species: 302587

305527
type: LocalParameter
value: 0.0

305526
type: LocalParameter
value: 0.0

305525
type: LocalParameter
value: 999999.0

305524
type: LocalParameter
value: 0.0

717949
type: SpeciesReference
stoichiometry: 1.0
species: 302949

717997
type: SpeciesReference
stoichiometry: 1.0
species: 302948

717961
type: SpeciesReference
stoichiometry: 1.0
species: 302975

717985
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303013
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: CO2_CO2

302503
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Alanine_C3H7NO2

303741
type: Reaction
kinetic law: 718553
product: 718541
product: 718529
reactant: 718517
notes: Abbreviation: R_SHCHC Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 5ephchc --> 2shchc + pyr Confidence Level: 2 JLR genes: LOCUS:BLBBGE_131#ABBREVIATION:menH#ECNUMBERS:4.2.99.20# proteins: NAME:SHCHC cynthase#ABBREVIATION:MenH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_131)
fast: false
reversible: false
name: _2-succinyl-6-hydroxy-2,4-cyclohexadiene 1-carboxylate synthase

305569
type: LocalParameter
value: 0.0

305568
type: LocalParameter
value: 0.0

305567
type: LocalParameter
value: 999999.0

305566
type: LocalParameter
value: 0.0

718541
type: SpeciesReference
stoichiometry: 1.0
species: 302893

718529
type: SpeciesReference
stoichiometry: 1.0
species: 302432

718517
type: SpeciesReference
stoichiometry: 1.0
species: 302468

302600
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

303077
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Valine_C5H11NO2

302910
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Shikimate_C7H9O5

303126
type: Reaction
product: 696881
reactant: 696832
notes: Abbreviation: R_ALAALAr Synonyms: _0 EC Number: 6.3.2.4 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : (2) ala-D + atp --> adp + alaala + h + pi Confidence Level: 2 JLR- added reversible form of ALAALA genes: LOCUS:BLBBGE_126#ABBREVIATION:ddlB#ECNUMBERS:6.3.2.4# proteins: NAME:D-alanine-D-alanine ligase A#ABBREVIATION:DdlA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_126)
product: 696857
name: D-alanine-D-alanine ligase (reversible)
product: 696893
reversible: false
fast: false
kinetic law: 696905
reactant: 696844
product: 696869

696881
type: SpeciesReference
stoichiometry: 1.0
species: 302659

696832
type: SpeciesReference
stoichiometry: 2.0
species: 302503

696857
type: SpeciesReference
stoichiometry: 1.0
species: 302493

696893
type: SpeciesReference
stoichiometry: 1.0
species: 302853

303964
type: LocalParameter
value: 0.0

303963
type: LocalParameter
value: 0.0

303962
type: LocalParameter
value: 999999.0

303960
type: LocalParameter
value: 0.0

696844
type: SpeciesReference
stoichiometry: 1.0
species: 302526

696869
type: SpeciesReference
stoichiometry: 1.0
species: 302507

302507
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Alanyl-D-alanine_C6H12N2O3

302475
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Acetate_C2H3O2

303746
type: Reaction
reactant: 718795
product: 718832
notes: Abbreviation: R_SHSL1 Synonyms: _2 EC Number: 4.2.99.9 SUBSYSTEM: Methionine Metabolism Equation: [c] : cys-L + suchms --> cyst-L + h + succ Confidence Level: 2 new EC - EC 2.5.1.48 NJ genes: LOCUS:BLBBGE_568#ABBREVIATION:metBC#ECNUMBERS:2.5.1.48# proteins: NAME:Cystathionine gamma-synthase-cystathionine beta-lyase#ABBREVIATION:MetBC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_568)
product: 718820
product: 718808
fast: false
reversible: false
reactant: 718783
kinetic law: 718845
name: O-succinylhomoserine lyase (L-cysteine)

718795
type: SpeciesReference
stoichiometry: 1.0
species: 302929

718832
type: SpeciesReference
stoichiometry: 1.0
species: 302924

302924
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Succinate_C4H4O4

718820
type: SpeciesReference
stoichiometry: 1.0
species: 302659

718808
type: SpeciesReference
stoichiometry: 1.0
species: 302544

718783
type: SpeciesReference
stoichiometry: 1.0
species: 302542

305591
type: LocalParameter
value: 0.0

305589
type: LocalParameter
value: 0.0

305588
type: LocalParameter
value: 999999.0

305586
type: LocalParameter
value: 0.0

303366
type: Reaction
kinetic law: 704937
product: 704925
product: 704913
reactant: 704901
notes: Abbreviation: R_FBAa Synonyms: _0 EC Number: 4.1.2.13 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : fdp <==> dhap + g3p Confidence Level: 2 genes: LOCUS:BLBBGE_476#ABBREVIATION:fbaA#ECNUMBERS:4.1.2.13# proteins: NAME:fructose-bisphosphate aldolase II#ABBREVIATION:FbaA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_476)
fast: false
reversible: true
name: fructose-bisphosphate aldolaseA

304542
type: LocalParameter
value: 0.0

304541
type: LocalParameter
value: 0.0

304540
type: LocalParameter
value: 999999.0

304539
type: LocalParameter
value: -999999.0

704925
type: SpeciesReference
stoichiometry: 1.0
species: 302620

704913
type: SpeciesReference
stoichiometry: 1.0
species: 302566

704901
type: SpeciesReference
stoichiometry: 1.0
species: 302601

302601
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Fructose 1,6-bisphosphate_C6H10O12P2

303285
type: Reaction
kinetic law: 703424
product: 703412
reactant: 703399
notes: Abbreviation: R_EX_co2_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : co2 <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: CO2 exchange

304358
type: LocalParameter
value: 0.0

304357
type: LocalParameter
value: 0.0

304356
type: LocalParameter
value: 999999.0

304355
type: LocalParameter
value: -999999.0

703412
type: SpeciesReference
stoichiometry: 1.0
species: 303013

703399
type: SpeciesReference
stoichiometry: 1.0
species: 302537

302537
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: CO2_CO2

303212
type: Reaction
kinetic law: 701066
product: 701054
reactant: 701042
notes: Abbreviation: R_DAPE Synonyms: _0 EC Number: 5.1.1.7 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : 26dap-LL <==> 26dap-M Confidence Level: 2 genes: LOCUS:BLBBGE_397#ABBREVIATION:dapF#ECNUMBERS:5.1.1.7# proteins: NAME:Diaminopimelate epimerase#ABBREVIATION:DapF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_397)
fast: false
reversible: true
name: diaminopimelate epimerase

304182
type: LocalParameter
value: 0.0

304181
type: LocalParameter
value: 0.0

304180
type: LocalParameter
value: 999999.0

304179
type: LocalParameter
value: -999999.0

701054
type: SpeciesReference
stoichiometry: 1.0
species: 302417

302417
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: meso-2,6-Diaminoheptanedioate_C7H14N2O4

701042
type: SpeciesReference
stoichiometry: 1.0
species: 302416

302416
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: LL-2,6-Diaminoheptanedioate_C7H14N2O4

303719
type: Reaction
reversible: false
name: pyridoxal kinase
fast: false
product: 717371
notes: Abbreviation: R_PYDXK Synonyms: _0 EC Number: 2.7.1.35 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + pydx --> adp + h + pydx5p Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
kinetic law: 717407
reactant: 717359
product: 717395
product: 717383
reactant: 717347

717371
type: SpeciesReference
stoichiometry: 1.0
species: 302493

305482
type: LocalParameter
value: 0.0

305481
type: LocalParameter
value: 0.0

305480
type: LocalParameter
value: 999999.0

305479
type: LocalParameter
value: 0.0

717359
type: SpeciesReference
stoichiometry: 1.0
species: 302890

717395
type: SpeciesReference
stoichiometry: 1.0
species: 302889

717383
type: SpeciesReference
stoichiometry: 1.0
species: 302659

717347
type: SpeciesReference
stoichiometry: 1.0
species: 302526

303614
type: Reaction
reactant: 713286
notes: Abbreviation: R_NTPTP1 Synonyms: _0 EC Number: 3.1.5.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dgtp + h2o --> dgsn + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_612#ABBREVIATION:dgt#ECNUMBERS:3.1.5.1# proteins: NAME:putative transmembrane HD family protein#ABBREVIATION:Dgt# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_612)
name: Nucleoside triphosphate tripolyhydrolase
reactant: 713298
kinetic law: 713334
reversible: false
product: 713310
fast: false
product: 713322

713286
type: SpeciesReference
stoichiometry: 1.0
species: 302565

713298
type: SpeciesReference
stoichiometry: 1.0
species: 302655

305182
type: LocalParameter
value: 0.0

305180
type: LocalParameter
value: 0.0

305179
type: LocalParameter
value: 999999.0

305177
type: LocalParameter
value: 0.0

713310
type: SpeciesReference
stoichiometry: 1.0
species: 302564

713322
type: SpeciesReference
stoichiometry: 1.0
species: 302865

302768
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: O-Phospho-L-homoserine_C4H8NO6P

303060
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Porphobilinogen_C10H13N2O4

303171
type: Reaction
product: 699331
product: 699367
product: 699319
reversible: false
reactant: 699295
reactant: 699271
product: 699343
name: Fatty acid biosynthesis (n-C16:0)
notes: Abbreviation: R_C160SN Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : actACP + (20) h + (6) malACP + (14) nadph --> (6) ACP + (6) co2 + (7) h2o + (14) nadp + palmACP Confidence Level: 2 tv genes: LOCUS:BLBBGE_037#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-# LOCUS:BLBBGE_346#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9# LOCUS:BLBBGE_057#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100# LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.179# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabG# NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI# NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_037) and (BLBBGE_079) and (BLBBGE_346) and (BLBBGE_057)
reactant: 699307
reactant: 699283
fast: false
product: 699355
kinetic law: 699379

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stoichiometry: 6.0
species: 302536

699367
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stoichiometry: 1.0
species: 302750

699319
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stoichiometry: 6.0
species: 302487

699295
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stoichiometry: 6.0
species: 302697

699271
type: SpeciesReference
stoichiometry: 1.0
species: 302489

302489
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Acetoacetyl-ACP_C15H25N2O9PRS

699343
type: SpeciesReference
stoichiometry: 7.0
species: 302655

699307
type: SpeciesReference
stoichiometry: 14.0
species: 302724

699283
type: SpeciesReference
stoichiometry: 20.0
species: 302659

699355
type: SpeciesReference
stoichiometry: 14.0
species: 302723

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value: 0.0

304079
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value: 0.0

304078
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value: 999999.0

304077
type: LocalParameter
value: 0.0

303277
type: Reaction
kinetic law: 703279
product: 703267
reactant: 703255
notes: Abbreviation: R_EX_ala_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : ala-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Alanine exchange

304340
type: LocalParameter
value: 0.0

304339
type: LocalParameter
value: 0.0

304338
type: LocalParameter
value: 999999.0

304337
type: LocalParameter
value: 0.0

703267
type: SpeciesReference
stoichiometry: 1.0
species: 303005

303005
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Alanine_C3H7NO2

703255
type: SpeciesReference
stoichiometry: 1.0
species: 302506

302437
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Carboxy-4-methyl-2-oxopentanoate_C7H8O5

303539
type: Reaction
notes: Abbreviation: R_NADH9 Synonyms: _0 EC Number: 1.6.5.3 SUBSYSTEM: Oxidative Phosphorylation Equation: [c] : 2dmmq8 + h + nadh --> 2dmmql8 + nad Confidence Level: 2 JLR genes: LOCUS:BLBBGE_193#ABBREVIATION:ndh#ECNUMBERS:1.16.1.-,-!-,1.6.99.3# proteins: NAME:NADH dehydrogenase II#ABBREVIATION:Ndh# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_193)
fast: false
reactant: 710851
product: 710887
reversible: false
reactant: 710875
kinetic law: 710911
name: NADH dehydrogenase (demethylmenaquinone-8 & 0 protons)
product: 710899
reactant: 710863

710851
type: SpeciesReference
stoichiometry: 1.0
species: 302422

302422
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Demethylmenaquinone 8_C50H70O2

710887
type: SpeciesReference
stoichiometry: 1.0
species: 302423

710875
type: SpeciesReference
stoichiometry: 1.0
species: 302720

304921
type: LocalParameter
value: 0.0

304920
type: LocalParameter
value: 0.0

304919
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value: 999999.0

304918
type: LocalParameter
value: 0.0

710899
type: SpeciesReference
stoichiometry: 1.0
species: 302719

710863
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303425
type: Reaction
kinetic law: 706799
product: 706787
reactant: 706775
notes: Abbreviation: R_GLYt Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: gly[e] <==> gly[c] Confidence Level: 2 NCD genes: LOCUS:BLBBGE_460#ABBREVIATION:glpF# proteins: NAME:MIP channel, glycerol diffusion#ABBREVIATION:GlpF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_460)
fast: false
reversible: true
name: Glycine transport via diffusion

304665
type: LocalParameter
value: 0.0

304664
type: LocalParameter
value: 0.0

304663
type: LocalParameter
value: 999999.0

304662
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value: -999999.0

706787
type: SpeciesReference
stoichiometry: 1.0
species: 302636

706775
type: SpeciesReference
stoichiometry: 1.0
species: 302637

303678
type: Reaction
reactant: 715357
reversible: false
name: phosphopantothenoylcysteine decarboxylase
notes: Abbreviation: R_PPCDC Synonyms: _0 EC Number: 4.1.1.36 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 4ppcys + h --> co2 + pan4p Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 715369
fast: false
product: 715393
product: 715381
kinetic law: 715405

715357
type: SpeciesReference
stoichiometry: 1.0
species: 302459

715369
type: SpeciesReference
stoichiometry: 1.0
species: 302659

715393
type: SpeciesReference
stoichiometry: 1.0
species: 302753

715381
type: SpeciesReference
stoichiometry: 1.0
species: 302536

305342
type: LocalParameter
value: 0.0

305341
type: LocalParameter
value: 0.0

305340
type: LocalParameter
value: 999999.0

305339
type: LocalParameter
value: 0.0

303731
type: Reaction
kinetic law: 718046
product: 718034
reactant: 718022
notes: Abbreviation: R_RPE Synonyms: _0 EC Number: 5.1.3.1 SUBSYSTEM: Pentose Phosphate Pathway Equation: [c] : ru5p-D <==> xu5p-D Confidence Level: 2 SMP genes: LOCUS:BLBBGE_347#ABBREVIATION:rpe#ECNUMBERS:5.1.3.1# proteins: NAME:D-ribulose-5-phosphate 3-epimerase#ABBREVIATION:Rpe# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_347)
fast: false
reversible: true
name: ribulose 5-phosphate 3-epimerase

305531
type: LocalParameter
value: 0.0

305530
type: LocalParameter
value: 0.0

305529
type: LocalParameter
value: 999999.0

305528
type: LocalParameter
value: -999999.0

718034
type: SpeciesReference
stoichiometry: 1.0
species: 303000

718022
type: SpeciesReference
stoichiometry: 1.0
species: 302900

303697
type: Reaction
kinetic law: 716309
product: 716297
reactant: 716285
notes: Abbreviation: R_PRMICIi Synonyms: _0 EC Number: 5.3.1.16 SUBSYSTEM: Histidine Metabolism Equation: [c] : prfp --> prlp Confidence Level: 2 JLR - added irreversible form of PRMICI genes: LOCUS:BLBBGE_438#ABBREVIATION:hisA#ECNUMBERS:5.3.1.16# proteins: NAME:Phosphoribosylformimino-5-amino-1-phosphoribosyl-4-imidazole carboxamide#ABBREVIATION:HisA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_438)
fast: false
reversible: false
name: _1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (irreversible)

305399
type: LocalParameter
value: 0.0

305397
type: LocalParameter
value: 0.0

305396
type: LocalParameter
value: 999999.0

305394
type: LocalParameter
value: 0.0

716297
type: SpeciesReference
stoichiometry: 1.0
species: 302875

716285
type: SpeciesReference
stoichiometry: 1.0
species: 302874

302874
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405

303757
type: Reaction
product: 719448
reactant: 719436
reversible: true
reactant: 719424
product: 719473
notes: Abbreviation: R_SULR Synonyms: _0 EC Number: 1.8.2.2 SUBSYSTEM: Cysteine Metabolism Equation: [c] : (3) h2o + h2s + (3) nadp <==> (5) h + (3) nadph + so3 Confidence Level: 2 JLR- EC number is 1.8.1.2? genes: LOCUS:BLBBGE_280#ABBREVIATION:cysI#ECNUMBERS:1.8.1.2# LOCUS:BLBBGE_279#ABBREVIATION:cysJ#ECNUMBERS:1.8.1.2,-!-,1.6.8.1# proteins: NAME:sulfite reductase#ABBREVIATION:CysIJ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_279 and BLBBGE_280)
name: sulfite reductase (NADPH2)
product: 719460
fast: false
reactant: 719412
kinetic law: 719485

719448
type: SpeciesReference
stoichiometry: 5.0
species: 302659

719436
type: SpeciesReference
stoichiometry: 3.0
species: 302723

719424
type: SpeciesReference
stoichiometry: 1.0
species: 302658

302658
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Hydrogen sulfide_H2S

719473
type: SpeciesReference
stoichiometry: 1.0
species: 302915

719460
type: SpeciesReference
stoichiometry: 3.0
species: 302724

719412
type: SpeciesReference
stoichiometry: 3.0
species: 302655

305632
type: LocalParameter
value: 0.0

305631
type: LocalParameter
value: 0.0

305630
type: LocalParameter
value: 999999.0

305629
type: LocalParameter
value: -999999.0

303078
type: Reaction
name: _4-Hydroxy-L-threonine synthase
reactant: 694742
fast: false
kinetic law: 694790
reactant: 694754
reversible: false
product: 694778
notes: Abbreviation: R_4HTHRS Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : h2o + phthr --> 4hthr + pi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_499#ABBREVIATION:thrC#ECNUMBERS:4.2.3.1# proteins: NAME:Threonine synthase#ABBREVIATION:ThrC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_499)
product: 694766

694742
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303814
type: LocalParameter
value: 0.0

303813
type: LocalParameter
value: 0.0

303812
type: LocalParameter
value: 999999.0

303810
type: LocalParameter
value: 0.0

694754
type: SpeciesReference
stoichiometry: 1.0
species: 302770

694778
type: SpeciesReference
stoichiometry: 1.0
species: 302853

694766
type: SpeciesReference
stoichiometry: 1.0
species: 302452

303130
type: Reaction
reactant: 696967
reactant: 696955
kinetic law: 697003
name: L-alanine reversible transport via proton symport
reversible: true
product: 696979
product: 696991
notes: Abbreviation: R_ALAt2r Synonyms: _0 SUBSYSTEM: Putative Transporters Equation: ala-L[e] + h[e] <==> ala-L[c] + h[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false

696967
type: SpeciesReference
stoichiometry: 1.0
species: 302660

696955
type: SpeciesReference
stoichiometry: 1.0
species: 302506

303972
type: LocalParameter
value: 0.0

303971
type: LocalParameter
value: 0.0

303970
type: LocalParameter
value: 999999.0

303969
type: LocalParameter
value: -999999.0

696979
type: SpeciesReference
stoichiometry: 1.0
species: 302504

696991
type: SpeciesReference
stoichiometry: 1.0
species: 302659

302512
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Anthranilate_C7H6NO2

303787
type: Reaction
fast: false
reactant: 721028
notes: Abbreviation: R_UAGCVT Synonyms: _0 EC Number: 2.5.1.7 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : pep + uacgam --> pi + uaccg Confidence Level: 2 genes: LOCUS:BLBBGE_135#ABBREVIATION:murA#ECNUMBERS:2.5.1.7# proteins: NAME:UDP-N-acetylglucosamine-enolpyruvate transferase#ABBREVIATION:MurA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_135)
reversible: false
reactant: 721040
kinetic law: 721077
product: 721052
name: UDP-N-acetylglucosamine 1-carboxyvinyltransferase
product: 721065

721028
type: SpeciesReference
stoichiometry: 1.0
species: 302760

302760
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Phosphoenolpyruvate_C3H2O6P

721040
type: SpeciesReference
stoichiometry: 1.0
species: 302964

302964
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405

305749
type: LocalParameter
value: 0.0

305747
type: LocalParameter
value: 0.0

305746
type: LocalParameter
value: 999999.0

305744
type: LocalParameter
value: 0.0

721052
type: SpeciesReference
stoichiometry: 1.0
species: 302853

721065
type: SpeciesReference
stoichiometry: 1.0
species: 302963

303082
type: Reaction
reactant: 695044
product: 695080
notes: Abbreviation: R_ACHBS Synonyms: _0 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 2obut + h + pyr --> 2ahbut + co2 Confidence Level: 2 JLR- I think the EC is 4.1.3.18 genes: LOCUS:BLBBGE_556#ABBREVIATION:ilvI#ECNUMBERS:2.2.1.6# LOCUS:BLBBGE_555#ABBREVIATION:ilvH#ECNUMBERS:2.2.1.6# proteins: NAME:acetolactate synthase III#ABBREVIATION:IlvHI# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_555 and BLBBGE_556)
kinetic law: 695092
reversible: false
product: 695068
name: _2-aceto-2-hydroxybutanoate synthase
reactant: 695056
fast: false
reactant: 695032

695044
type: SpeciesReference
stoichiometry: 1.0
species: 302659

695080
type: SpeciesReference
stoichiometry: 1.0
species: 302536

303832
type: LocalParameter
value: 0.0

303831
type: LocalParameter
value: 0.0

303830
type: LocalParameter
value: 999999.0

303829
type: LocalParameter
value: 0.0

695068
type: SpeciesReference
stoichiometry: 1.0
species: 302418

695056
type: SpeciesReference
stoichiometry: 1.0
species: 302893

695032
type: SpeciesReference
stoichiometry: 1.0
species: 302427

303377
type: Reaction
kinetic law: 705275
fast: false
reactant: 705227
name: aminomethyltransferase
product: 705251
reactant: 705239
notes: Abbreviation: R_FOMETR Synonyms: _0 EC Number: 2.1.2.10 SUBSYSTEM: Cofactor Metabolism Equation: [c] : 5fthf + h <==> h2o + methf Confidence Level: 2 RM genes: LOCUS:BLBBGE_188#ABBREVIATION:gcvT#ECNUMBERS:2.1.2.10# proteins: NAME:Glycine cleavage complex, T#ABBREVIATION:GcvT# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_188)
product: 705263
reversible: true

304564
type: LocalParameter
value: 0.0

304563
type: LocalParameter
value: 0.0

304562
type: LocalParameter
value: 999999.0

304561
type: LocalParameter
value: -999999.0

705227
type: SpeciesReference
stoichiometry: 1.0
species: 302469

302469
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Formyltetrahydrofolate_C20H21N7O7

705251
type: SpeciesReference
stoichiometry: 1.0
species: 302655

705239
type: SpeciesReference
stoichiometry: 1.0
species: 302659

705263
type: SpeciesReference
stoichiometry: 1.0
species: 302705

303370
type: Reaction
reactant: 705009
product: 705033
kinetic law: 705045
product: 705021
reversible: false
notes: Abbreviation: R_FBP Synonyms: _0 EC Number: 3.1.3.11 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : fdp + h2o --> f6p + pi Confidence Level: 2 SMP genes: LOCUS:BLBBGE_509#ABBREVIATION:fbp#ECNUMBERS:3.1.3.11# proteins: NAME:fructose-1,6-bisphophatase#ABBREVIATION:Fbp# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_509)
reactant: 704997
fast: false
name: fructose-bisphosphatase

705009
type: SpeciesReference
stoichiometry: 1.0
species: 302655

705033
type: SpeciesReference
stoichiometry: 1.0
species: 302853

304550
type: LocalParameter
value: 0.0

304549
type: LocalParameter
value: 0.0

304548
type: LocalParameter
value: 999999.0

304547
type: LocalParameter
value: 0.0

705021
type: SpeciesReference
stoichiometry: 1.0
species: 302597

704997
type: SpeciesReference
stoichiometry: 1.0
species: 302601

303551
type: Reaction
fast: false
name: nucleoside-diphosphate kinase (ATP:UDP)
product: 711361
reactant: 711336
product: 711349
reversible: true
kinetic law: 711373
notes: Abbreviation: R_NDPK2 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + udp <==> adp + utp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions. genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)
reactant: 711324

711361
type: SpeciesReference
stoichiometry: 1.0
species: 302990

711336
type: SpeciesReference
stoichiometry: 1.0
species: 302975

711349
type: SpeciesReference
stoichiometry: 1.0
species: 302493

304947
type: LocalParameter
value: 0.0

304946
type: LocalParameter
value: 0.0

304945
type: LocalParameter
value: 999999.0

304944
type: LocalParameter
value: -999999.0

711324
type: SpeciesReference
stoichiometry: 1.0
species: 302526

303655
type: Reaction
kinetic law: 714745
product: 714733
reactant: 714721
notes: Abbreviation: R_PGM Synonyms: _0 EC Number: 5.4.2.1 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : 2pg <==> 3pg Confidence Level: 2 SMP genes: LOCUS:BLBBGE_231#ABBREVIATION:gpmA#ECNUMBERS:5.4.2.1# proteins: NAME:phosphoglycerate mutase I#ABBREVIATION:GpmA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_231)
fast: false
reversible: true
name: phosphoglycerate mutase

305283
type: LocalParameter
value: 0.0

305282
type: LocalParameter
value: 0.0

305281
type: LocalParameter
value: 999999.0

305280
type: LocalParameter
value: -999999.0

714733
type: SpeciesReference
stoichiometry: 1.0
species: 302446

714721
type: SpeciesReference
stoichiometry: 1.0
species: 302431

302431
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Glycerate 2-phosphate_C3H4O7P

303402
type: Reaction
fast: false
kinetic law: 706087
name: guanylate kinase (GMP:ATP)
reversible: true
notes: Abbreviation: R_GK1 Synonyms: _0 EC Number: 2.7.4.8 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + gmp <==> adp + gdp Confidence Level: 2 genes: LOCUS:BLBBGE_298#ABBREVIATION:gmk#ECNUMBERS:2.7.4.8# proteins: NAME:Guanylate kinase#ABBREVIATION:Gmk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_298)
product: 706063
reactant: 706039
product: 706075
reactant: 706051

304619
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value: 0.0

304618
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value: 0.0

304617
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value: 999999.0

304616
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value: -999999.0

706063
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stoichiometry: 1.0
species: 302493

706039
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stoichiometry: 1.0
species: 302526

706075
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stoichiometry: 1.0
species: 302626

706051
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stoichiometry: 1.0
species: 302648

303118
type: Reaction
name: adenosylhomocysteinase
reactant: 696444
product: 696456
reversible: true
kinetic law: 696480
reactant: 696432
fast: false
notes: Abbreviation: R_AHC Synonyms: _0 EC Number: 3.3.1.1 SUBSYSTEM: Methionine Metabolism Equation: [c] : ahcys + h2o <==> adn + hcys-L Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 696468

696444
type: SpeciesReference
stoichiometry: 1.0
species: 302655

696456
type: SpeciesReference
stoichiometry: 1.0
species: 302492

303934
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value: 0.0

303933
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value: 0.0

303932
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value: 999999.0

303931
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value: -999999.0

696432
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stoichiometry: 1.0
species: 302495

302495
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

696468
type: SpeciesReference
stoichiometry: 1.0
species: 302663

302663
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Homocysteine_C4H9NO2S

302919
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Sulfate_O4S

303738
type: Reaction
product: 718432
reactant: 718408
product: 718420
name: serine O-acetyltransferase
reversible: true
fast: false
notes: Abbreviation: R_SERAT Synonyms: _4 EC Number: 2.3.1.30 SUBSYSTEM: Cysteine Metabolism Equation: [c] : accoa + ser-L <==> acser + coa Confidence Level: 2 genes: LOCUS:BLBBGE_276#ABBREVIATION:cysE#ECNUMBERS:2.3.1.30# proteins: NAME:Serine acetyltransferase#ABBREVIATION:CysE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_276)
reactant: 718395
kinetic law: 718444

718432
type: SpeciesReference
stoichiometry: 1.0
species: 302538

718408
type: SpeciesReference
stoichiometry: 1.0
species: 302905

718420
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stoichiometry: 1.0
species: 302488

302488
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: O-Acetyl-L-serine_C5H9NO4

718395
type: SpeciesReference
stoichiometry: 1.0
species: 302479

305561
type: LocalParameter
value: 0.0

305559
type: LocalParameter
value: 0.0

305558
type: LocalParameter
value: 999999.0

305556
type: LocalParameter
value: -999999.0

303417
type: Reaction
product: 706581
kinetic law: 706593
product: 706557
notes: Abbreviation: R_GLYCL Synonyms: _0 SUBSYSTEM: Folate Metabolism Equation: [c] : gly + nad + thf <==> co2 + mlthf + nadh + nh4 Confidence Level: 2 genes: LOCUS:BLBBGE_147#ABBREVIATION:lpd#ECNUMBERS:1.8.1.4# LOCUS:BLBBGE_616#ABBREVIATION:gcvP#ECNUMBERS:1.4.4.2# LOCUS:BLBBGE_418#ABBREVIATION:gcvH# LOCUS:BLBBGE_188#ABBREVIATION:gcvT#ECNUMBERS:2.1.2.10# proteins: NAME:Glycine cleavage complex, T#ABBREVIATION:GcvT# NAME:glycine cleavage complex, H#ABBREVIATION:GcvH# NAME:Glycine cleavage complex, P#ABBREVIATION:GcvP# NAME:dihydrolipoamide dehydrogenase#ABBREVIATION:LpdA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_147) and (BLBBGE_616) and (BLBBGE_188) and (BLBBGE_418)
reactant: 706509
reversible: true
fast: false
reactant: 706533
name: Glycine Cleavage System
product: 706545
product: 706569
reactant: 706521

706581
type: SpeciesReference
stoichiometry: 1.0
species: 302725

304649
type: LocalParameter
value: 0.0

304648
type: LocalParameter
value: 0.0

304647
type: LocalParameter
value: 999999.0

304646
type: LocalParameter
value: -999999.0

706557
type: SpeciesReference
stoichiometry: 1.0
species: 302708

302708
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5,10-Methylenetetrahydrofolate_C20H21N7O6

706509
type: SpeciesReference
stoichiometry: 1.0
species: 302636

706533
type: SpeciesReference
stoichiometry: 1.0
species: 302934

706545
type: SpeciesReference
stoichiometry: 1.0
species: 302536

706569
type: SpeciesReference
stoichiometry: 1.0
species: 302720

706521
type: SpeciesReference
stoichiometry: 1.0
species: 302719

303682
type: Reaction
product: 715551
notes: Abbreviation: R_PPND Synonyms: _0 EC Number: 1.3.1.12 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : nad + pphn --> 34hpp + co2 + nadh Confidence Level: 2 genes: LOCUS:BLBBGE_343#ABBREVIATION:tyrA#ECNUMBERS:5.4.99.5,-!-,1.3.1.12# proteins: NAME:Chorismate mutase T#ABBREVIATION:TyrA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_343)
name: prephenate dehydrogenase
product: 715564
kinetic law: 715576
reactant: 715527
reversible: false
fast: false
product: 715539
reactant: 715515

715551
type: SpeciesReference
stoichiometry: 1.0
species: 302536

715564
type: SpeciesReference
stoichiometry: 1.0
species: 302720

305350
type: LocalParameter
value: 0.0

305349
type: LocalParameter
value: 0.0

305348
type: LocalParameter
value: 999999.0

305347
type: LocalParameter
value: 0.0

715527
type: SpeciesReference
stoichiometry: 1.0
species: 302864

302864
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Prephenate_C10H8O6

715539
type: SpeciesReference
stoichiometry: 1.0
species: 302433

715515
type: SpeciesReference
stoichiometry: 1.0
species: 302719

303221
type: Reaction
kinetic law: 701416
reactant: 701380
fast: false
reactant: 701356
reactant: 701368
product: 701392
name: _3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase
notes: Abbreviation: R_DDPA Synonyms: _0 EC Number: 2.5.1.54 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : e4p + h2o + pep --> 2dda7p + pi Confidence Level: 2 genes: LOCUS:BPLAN_296#ABBREVIATION:aroGpheA#ECNUMBERS:2.5.1.54,-!-,4.2.1.51,-!-,5.4.99.5# proteins: NAME:_bifunctional putative phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase#ABBREVIATION:AroGPheA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_344)
product: 701404
reversible: false

304204
type: LocalParameter
value: 0.0

304203
type: LocalParameter
value: 0.0

304202
type: LocalParameter
value: 999999.0

304201
type: LocalParameter
value: 0.0

701380
type: SpeciesReference
stoichiometry: 1.0
species: 302760

701356
type: SpeciesReference
stoichiometry: 1.0
species: 302593

701368
type: SpeciesReference
stoichiometry: 1.0
species: 302655

701392
type: SpeciesReference
stoichiometry: 1.0
species: 302421

701404
type: SpeciesReference
stoichiometry: 1.0
species: 302853

303749
type: Reaction
kinetic law: 719038
product: 719026
product: 719014
reactant: 719002
notes: Abbreviation: R_SUCBZS Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 2shchc --> h2o + sucbz Confidence Level: 2 genes: LOCUS:BLBBGE_270#ABBREVIATION:menC#ECNUMBERS:4.2.1.-# proteins: NAME:O-succinylbenzoate-CoA synthase#ABBREVIATION:MenC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_270)
fast: false
reversible: false
name: O-succinylbenzoate-CoA synthase

305606
type: LocalParameter
value: 0.0

305604
type: LocalParameter
value: 0.0

305603
type: LocalParameter
value: 999999.0

305601
type: LocalParameter
value: 0.0

719026
type: SpeciesReference
stoichiometry: 1.0
species: 302923

302923
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: o-Succinylbenzoate_C11H8O5

719014
type: SpeciesReference
stoichiometry: 1.0
species: 302655

719002
type: SpeciesReference
stoichiometry: 1.0
species: 302432

303606
type: Reaction
name: Nucleoside triphosphate pyrophosphorylase (datp)
product: 713043
kinetic law: 713056
product: 713031
reversible: false
reactant: 713006
product: 713019
notes: Abbreviation: R_NTPP5 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : datp + h2o --> damp + h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
fast: false
reactant: 712994

713043
type: SpeciesReference
stoichiometry: 1.0
species: 302865

305067
type: LocalParameter
value: 0.0

305066
type: LocalParameter
value: 0.0

305065
type: LocalParameter
value: 999999.0

305064
type: LocalParameter
value: 0.0

713031
type: SpeciesReference
stoichiometry: 1.0
species: 302659

713006
type: SpeciesReference
stoichiometry: 1.0
species: 302655

713019
type: SpeciesReference
stoichiometry: 1.0
species: 302550

712994
type: SpeciesReference
stoichiometry: 1.0
species: 302551

303087
type: Reaction
notes: Abbreviation: R_ACODA Synonyms: _0 EC Number: 3.5.1.16 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : acorn + h2o --> ac + orn Confidence Level: 2 genes: LOCUS:BLBBGE_320#ABBREVIATION:argE#ECNUMBERS:3.5.1.16# proteins: NAME:acetylornithine deacetylase#ABBREVIATION:ArgE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_320)
reversible: false
fast: false
reactant: 695239
name: acetylornithine deacetylase
reactant: 695227
product: 695251
product: 695263
kinetic law: 695275

695239
type: SpeciesReference
stoichiometry: 1.0
species: 302655

695227
type: SpeciesReference
stoichiometry: 1.0
species: 302485

695251
type: SpeciesReference
stoichiometry: 1.0
species: 302475

695263
type: SpeciesReference
stoichiometry: 1.0
species: 302744

302744
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Ornithine_C5H13N2O2

303846
type: LocalParameter
value: 0.0

303845
type: LocalParameter
value: 0.0

303844
type: LocalParameter
value: 999999.0

303842
type: LocalParameter
value: 0.0

303180
type: Reaction
kinetic law: 699826
product: 699814
reactant: 699802
notes: Abbreviation: R_CHORM Synonyms: _0 EC Number: 5.4.99.5 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : chor <==> pphn Confidence Level: 2 genes: LOCUS:BLBBGE_341#ABBREVIATION:pheA#ECNUMBERS:5.4.99.5,-!-,4.2.1.51# LOCUS:BLBBGE_343#ABBREVIATION:tyrA#ECNUMBERS:5.4.99.5,-!-,1.3.1.12# LOCUS:BLBBGE_344#ABBREVIATION:aroGpheA#ECNUMBERS:2.5.1.54,-!-,4.2.1.51,-!-,5.4.99.5# proteins: NAME:_bifunctional putative phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase#ABBREVIATION:AroGPheA# NAME:Chorismate mutase T#ABBREVIATION:TyrA# NAME:Chorismate mutase P#ABBREVIATION:PheA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_343) or (BLBBGE_341) or (BLBBGE_344)
fast: false
reversible: true
name: chorismate mutase

304102
type: LocalParameter
value: 0.0

304101
type: LocalParameter
value: 0.0

304100
type: LocalParameter
value: 999999.0

304099
type: LocalParameter
value: -999999.0

699814
type: SpeciesReference
stoichiometry: 1.0
species: 302864

699802
type: SpeciesReference
stoichiometry: 1.0
species: 302531

303381
type: Reaction
kinetic law: 705348
product: 705335
reactant: 705323
notes: Abbreviation: R_FRUt1r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: fru[e] <==> fru[c] Confidence Level: 2 genes: LOCUS:BLBBGE_199 proteins: NAME:ABC transporter, ATP-binding and permease protein citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_199)
fast: false
reversible: true
name: D-fructose transport in via uniport

304572
type: LocalParameter
value: 0.0

304571
type: LocalParameter
value: 0.0

304570
type: LocalParameter
value: 999999.0

304569
type: LocalParameter
value: -999999.0

705335
type: SpeciesReference
stoichiometry: 1.0
species: 302614

705323
type: SpeciesReference
stoichiometry: 1.0
species: 302616

303543
type: Reaction
product: 711068
product: 711056
product: 711032
name: NAD synthase (nh3)
product: 711044
reactant: 711020
kinetic law: 711081
reversible: false
reactant: 711008
fast: false
reactant: 710996
notes: Abbreviation: R_NADS1 Synonyms: _0 EC Number: 6.3.1.5 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + dnad + nh4 --> amp + h + nad + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_571#ABBREVIATION:nadE#ECNUMBERS:6.3.5.1# proteins: NAME:Deamido-NAD ammonia ligase or NAD synthetase#ABBREVIATION:NadE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_571)

711068
type: SpeciesReference
stoichiometry: 1.0
species: 302865

711056
type: SpeciesReference
stoichiometry: 1.0
species: 302719

711032
type: SpeciesReference
stoichiometry: 1.0
species: 302511

711044
type: SpeciesReference
stoichiometry: 1.0
species: 302659

711020
type: SpeciesReference
stoichiometry: 1.0
species: 302725

304931
type: LocalParameter
value: 0.0

304930
type: LocalParameter
value: 0.0

304929
type: LocalParameter
value: 999999.0

304927
type: LocalParameter
value: 0.0

711008
type: SpeciesReference
stoichiometry: 1.0
species: 302580

302580
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Deamino-NAD+_C21H24N6O15P2

710996
type: SpeciesReference
stoichiometry: 1.0
species: 302526

303761
type: Reaction
product: 719690
kinetic law: 719714
product: 719677
product: 719702
notes: Abbreviation: R_THMabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + thm[e] --> adp[c] + h[c] + pi[c] + thm[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reversible: false
name: thiamine transport via ABC system
reactant: 719653
product: 719665
reactant: 719629
fast: false
reactant: 719641

719690
type: SpeciesReference
stoichiometry: 1.0
species: 302853

305647
type: LocalParameter
value: 0.0

305646
type: LocalParameter
value: 0.0

305645
type: LocalParameter
value: 999999.0

305644
type: LocalParameter
value: 0.0

719677
type: SpeciesReference
stoichiometry: 1.0
species: 302659

719702
type: SpeciesReference
stoichiometry: 1.0
species: 302935

302935
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Thiamin_C12H17N4OS

719653
type: SpeciesReference
stoichiometry: 1.0
species: 302938

302938
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Thiamin_C12H17N4OS

719665
type: SpeciesReference
stoichiometry: 1.0
species: 302493

719629
type: SpeciesReference
stoichiometry: 1.0
species: 302526

719641
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303322
type: Reaction
kinetic law: 704114
product: 704102
reactant: 704090
notes: Abbreviation: R_EX_lys_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : lys-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Lysine exchange

304444
type: LocalParameter
value: 0.0

304443
type: LocalParameter
value: 0.0

304442
type: LocalParameter
value: 999999.0

304440
type: LocalParameter
value: 0.0

704102
type: SpeciesReference
stoichiometry: 1.0
species: 303042

704090
type: SpeciesReference
stoichiometry: 1.0
species: 302696

303098
type: Reaction
product: 695699
reversible: true
notes: Abbreviation: R_ADCL Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 4adcho <==> 4abz + h + pyr Confidence Level: 2 EC: 4.1.3.38 IT genes: LOCUS:BLBBGE_455#ABBREVIATION:ilvE#ECNUMBERS:4.1.3.38# proteins: NAME:Aminodeoxychorismate lyase#ABBREVIATION:IlvE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_455)
name: _4-aminobenzoate synthase
product: 695687
product: 695675
fast: false
kinetic law: 695711
reactant: 695663

695699
type: SpeciesReference
stoichiometry: 1.0
species: 302893

695687
type: SpeciesReference
stoichiometry: 1.0
species: 302659

695675
type: SpeciesReference
stoichiometry: 1.0
species: 302450

302450
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _4-Aminobenzoate_C7H6NO2

303878
type: LocalParameter
value: 0.0

303877
type: LocalParameter
value: 0.0

303876
type: LocalParameter
value: 999999.0

303874
type: LocalParameter
value: -999999.0

695663
type: SpeciesReference
stoichiometry: 1.0
species: 302451

302451
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _4-amino-4-deoxychorismate_C10H10NO5

303386
type: Reaction
fast: false
notes: Abbreviation: R_FUMt2_2 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: fum[e] + (2) h[e] --> fum[c] + (2) h[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_358#ABBREVIATION:dctA# proteins: NAME:C4-dicarboxylate transporter#ABBREVIATION:DctA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_358)
reactant: 705481
reversible: false
kinetic law: 705530
reactant: 705493
name: Fumarate transport via proton symport (2 H)
product: 705505
product: 705518

705481
type: SpeciesReference
stoichiometry: 1.0
species: 302618

302618
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Fumarate_C4H2O4

304586
type: LocalParameter
value: 0.0

304585
type: LocalParameter
value: 0.0

304584
type: LocalParameter
value: 999999.0

304582
type: LocalParameter
value: 0.0

705493
type: SpeciesReference
stoichiometry: 2.0
species: 302660

705505
type: SpeciesReference
stoichiometry: 1.0
species: 302617

302617
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Fumarate_C4H2O4

705518
type: SpeciesReference
stoichiometry: 2.0
species: 302659

302739
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: all-trans-Octaprenyl diphosphate_C40H65O7P2

303031
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Glycolate_C2H3O3

303172
type: Reaction
reactant: 699415
product: 699451
product: 699487
reversible: false
product: 699439
product: 699463
kinetic law: 699499
reactant: 699391
name: Fatty acid biosynthesis (n-C16:1)
notes: Abbreviation: R_C161SN Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : actACP + (19) h + (6) malACP + (13) nadph --> (6) ACP + (6) co2 + (7) h2o + hdeACP + (13) nadp Confidence Level: 2 tv genes: LOCUS:BLBBGE_037#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-# LOCUS:none#ABBREVIATION:fabA#ECNUMBERS:4.2.1.60# LOCUS:BLBBGE_346#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9# LOCUS:BLBBGE_057#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100# LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.179# LOCUS:BLBBGE_111#ABBREVIATION:fabH#ECNUMBERS:2.3.1.41# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase#ABBREVIATION:FabH# NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabG# NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI# NAME:beta-hydroxydecanoyl thioester dehydrase#ABBREVIATION:FabA# NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_037) and (BLBBGE_079) or (BLBBGE_111) and (BLBBGE_057) and (BLBBGE_346)
product: 699475
reactant: 699427
reactant: 699403
fast: false

699415
type: SpeciesReference
stoichiometry: 6.0
species: 302697

699451
type: SpeciesReference
stoichiometry: 6.0
species: 302536

699487
type: SpeciesReference
stoichiometry: 13.0
species: 302723

699439
type: SpeciesReference
stoichiometry: 6.0
species: 302487

699463
type: SpeciesReference
stoichiometry: 7.0
species: 302655

304084
type: LocalParameter
value: 0.0

304083
type: LocalParameter
value: 0.0

304082
type: LocalParameter
value: 999999.0

304081
type: LocalParameter
value: 0.0

699391
type: SpeciesReference
stoichiometry: 1.0
species: 302489

699475
type: SpeciesReference
stoichiometry: 1.0
species: 302664

699427
type: SpeciesReference
stoichiometry: 13.0
species: 302724

699403
type: SpeciesReference
stoichiometry: 19.0
species: 302659

303784
type: Reaction
reactant: 720883
notes: Abbreviation: R_UAAGDS Synonyms: _0 EC Number: 6.3.2.13 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : 26dap-M + atp + uamag --> adp + h + pi + ugmd Confidence Level: 2 genes: LOCUS:BLBBGE_390#ABBREVIATION:murE#ECNUMBERS:6.3.2.13# proteins: NAME:UDP-N-acetylmuramoxylalanyl-D-glutamate 2,6-diaminopimelate ligase#ABBREVIATION:MurE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_390)
reactant: 720895
product: 720919
reversible: false
kinetic law: 720956
fast: false
product: 720932
product: 720907
product: 720944
reactant: 720871
name: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase

720883
type: SpeciesReference
stoichiometry: 1.0
species: 302526

720895
type: SpeciesReference
stoichiometry: 1.0
species: 302969

720919
type: SpeciesReference
stoichiometry: 1.0
species: 302659

305738
type: LocalParameter
value: 0.0

305737
type: LocalParameter
value: 0.0

305736
type: LocalParameter
value: 999999.0

305735
type: LocalParameter
value: 0.0

720932
type: SpeciesReference
stoichiometry: 1.0
species: 302853

720907
type: SpeciesReference
stoichiometry: 1.0
species: 302493

720944
type: SpeciesReference
stoichiometry: 1.0
species: 302978

302978
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405

720871
type: SpeciesReference
stoichiometry: 1.0
species: 302417

303766
type: Reaction
notes: Abbreviation: R_TKT1 Synonyms: _0 EC Number: 2.2.1.1 SUBSYSTEM: Pentose Phosphate Pathway Equation: [c] : r5p + xu5p-D <==> g3p + s7p Confidence Level: 2 SMP Two reactions for transketolase: TKT1 and TKT2 genes: LOCUS:BLBBGE_403#ABBREVIATION:tkt#ECNUMBERS:2.2.1.1# LOCUS:BLBBGE_404#ABBREVIATION:tkt#ECNUMBERS:2.2.1.1# proteins: NAME:transketolase N-terminal subunit#ABBREVIATION:Tkt# NAME:transketolase C-terminal subunit#ABBREVIATION:Tkt# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_403 and BLBBGE_404)
product: 719968
name: transketolase
kinetic law: 719980
reversible: true
reactant: 719944
product: 719956
reactant: 719932
fast: false

719968
type: SpeciesReference
stoichiometry: 1.0
species: 302903

302903
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Sedoheptulose 7-phosphate_C7H13O10P

305666
type: LocalParameter
value: 0.0

305665
type: LocalParameter
value: 0.0

305664
type: LocalParameter
value: 999999.0

305663
type: LocalParameter
value: -999999.0

719944
type: SpeciesReference
stoichiometry: 1.0
species: 303000

719956
type: SpeciesReference
stoichiometry: 1.0
species: 302620

719932
type: SpeciesReference
stoichiometry: 1.0
species: 302898

303397
type: Reaction
product: 705859
reactant: 705835
notes: Abbreviation: R_GARFT Synonyms: _1 EC Number: 2.1.2.2 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : 10fthf + gar --> fgam + h + thf Confidence Level: 2 genes: LOCUS:BLBBGE_481#ABBREVIATION:purN#ECNUMBERS:2.1.2.2# proteins: NAME:phosphoribosylglycinamide formytransferase#ABBREVIATION:PurN# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_481)
fast: false
kinetic law: 705883
name: phosphoribosylglycinamide formyltransferase
reactant: 705823
reversible: false
product: 705871
product: 705847

705859
type: SpeciesReference
stoichiometry: 1.0
species: 302659

705835
type: SpeciesReference
stoichiometry: 1.0
species: 302624

304607
type: LocalParameter
value: 0.0

304606
type: LocalParameter
value: 0.0

304605
type: LocalParameter
value: 999999.0

304604
type: LocalParameter
value: 0.0

705823
type: SpeciesReference
stoichiometry: 1.0
species: 302407

705871
type: SpeciesReference
stoichiometry: 1.0
species: 302934

705847
type: SpeciesReference
stoichiometry: 1.0
species: 302605

303390
type: Reaction
reactant: 705630
reversible: true
kinetic law: 705667
reactant: 705617
notes: Abbreviation: R_G3PD5 Synonyms: _0 EC Number: 1.1.5.3 SUBSYSTEM: Oxidative Phosphorylation Equation: [c] : glyc3p + mqn8 <==> dhap + mql8 Confidence Level: 2 JLR genes: LOCUS:BLBBGE_458#ABBREVIATION:glpD#ECNUMBERS:1.1.5.3# proteins: NAME:glycerol-3-phosphate dehydrogenase#ABBREVIATION:GlpD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_458)
product: 705643
name: glycerol-3-phosphate dehydrogenase (ubiquinone-8)
product: 705655
fast: false

705630
type: SpeciesReference
stoichiometry: 1.0
species: 302710

304594
type: LocalParameter
value: 0.0

304593
type: LocalParameter
value: 0.0

304592
type: LocalParameter
value: 999999.0

304591
type: LocalParameter
value: -999999.0

705617
type: SpeciesReference
stoichiometry: 1.0
species: 302641

705643
type: SpeciesReference
stoichiometry: 1.0
species: 302566

705655
type: SpeciesReference
stoichiometry: 1.0
species: 302709

302463
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Amino-6-(5'-phosphoribitylamino)uracil_C9H15N4O9P

302928
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Succinyl-CoA_C25H35N7O19P3S

303634
type: Reaction
fast: false
reactant: 713914
reactant: 713902
kinetic law: 713950
product: 713926
name: _2-oxoglutarate decarboxylase
reactant: 713890
notes: Abbreviation: R_OXGDC2 Synonyms: _1 EC Number: 4.1.1.71 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : akg + h + thmpp --> co2 + ssaltpp Confidence Level: 2 JLR genes: LOCUS:BLBBGE_056#ABBREVIATION:menD#ECNUMBERS:4.1.1.71,-!-,2.2.1.9# proteins: NAME:bifunctional 2-oxoglutarate decarboxylase/2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase#ABBREVIATION:MenD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_056)
reversible: false
product: 713938

713914
type: SpeciesReference
stoichiometry: 1.0
species: 302939

713902
type: SpeciesReference
stoichiometry: 1.0
species: 302659

305227
type: LocalParameter
value: 0.0

305226
type: LocalParameter
value: 0.0

305225
type: LocalParameter
value: 999999.0

305224
type: LocalParameter
value: 0.0

713926
type: SpeciesReference
stoichiometry: 1.0
species: 302536

713890
type: SpeciesReference
stoichiometry: 1.0
species: 302500

713938
type: SpeciesReference
stoichiometry: 1.0
species: 302920

303739
type: Reaction
reactant: 718456
fast: false
reversible: false
product: 718480
kinetic law: 718505
name: L-serine via sodium symport
product: 718493
notes: Abbreviation: R_SERt4 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: na1[e] + ser-L[e] --> na1[c] + ser-L[c] Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 718468

718456
type: SpeciesReference
stoichiometry: 1.0
species: 302714

718480
type: SpeciesReference
stoichiometry: 1.0
species: 302713

305565
type: LocalParameter
value: 0.0

305564
type: LocalParameter
value: 0.0

305563
type: LocalParameter
value: 999999.0

305562
type: LocalParameter
value: 0.0

718493
type: SpeciesReference
stoichiometry: 1.0
species: 302905

718468
type: SpeciesReference
stoichiometry: 1.0
species: 302908

303758
type: Reaction
reactant: 719509
notes: Abbreviation: R_TALA Synonyms: _0 EC Number: 2.2.1.2 SUBSYSTEM: Pentose Phosphate Pathway Equation: [c] : g3p + s7p <==> e4p + f6p Confidence Level: 2 SMP genes: LOCUS:BLBBGE_213#ABBREVIATION:tal#ECNUMBERS:2.2.1.2# proteins: NAME:transaldolase#ABBREVIATION:Tal# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_213)
product: 719521
reactant: 719497
product: 719533
name: transaldolase
fast: false
reversible: true
kinetic law: 719545

719509
type: SpeciesReference
stoichiometry: 1.0
species: 302903

719521
type: SpeciesReference
stoichiometry: 1.0
species: 302593

719497
type: SpeciesReference
stoichiometry: 1.0
species: 302620

719533
type: SpeciesReference
stoichiometry: 1.0
species: 302597

305636
type: LocalParameter
value: 0.0

305635
type: LocalParameter
value: 0.0

305634
type: LocalParameter
value: 999999.0

305633
type: LocalParameter
value: -999999.0

303079
type: Reaction
reactant: 694814
product: 694839
reactant: 694826
kinetic law: 694888
fast: false
product: 694851
product: 694864
reactant: 694802
notes: Abbreviation: R_ACCOACr Synonyms: _0 EC Number: 6.4.1.2 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : accoa + atp + hco3 --> adp + h + malcoa + pi Confidence Level: 2 NCD genes: LOCUS:BLBBGE_154#ABBREVIATION:accA#ECNUMBERS:6.4.1.2# LOCUS:BLBBGE_477#ABBREVIATION:accD#ECNUMBERS:6.4.1.2# LOCUS:BLBBGE_516#ABBREVIATION:accB# LOCUS:BLBBGE_517#ABBREVIATION:accC#ECNUMBERS:6.3.4.14# proteins: NAME:AcetylCoA carboxylase#ABBREVIATION:Acc# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_154 and BLBBGE_516 and BLBBGE_517 and BLBBGE_477)
reversible: false
name: acetyl-CoA carboxylase, reversible reaction
product: 694876

694814
type: SpeciesReference
stoichiometry: 1.0
species: 302526

694839
type: SpeciesReference
stoichiometry: 1.0
species: 302493

694826
type: SpeciesReference
stoichiometry: 1.0
species: 302662

303818
type: LocalParameter
value: 0.0

303817
type: LocalParameter
value: 0.0

303816
type: LocalParameter
value: 999999.0

303815
type: LocalParameter
value: 0.0

694851
type: SpeciesReference
stoichiometry: 1.0
species: 302659

694864
type: SpeciesReference
stoichiometry: 1.0
species: 302701

694802
type: SpeciesReference
stoichiometry: 1.0
species: 302479

694876
type: SpeciesReference
stoichiometry: 1.0
species: 302853

303378
type: Reaction
kinetic law: 705311
product: 705299
reactant: 705287
notes: Abbreviation: R_FORt Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: for[e] <==> for[c] Confidence Level: 1 renamed from FORTR to FORt NCD genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: formate transport via diffusion

304568
type: LocalParameter
value: 0.0

304567
type: LocalParameter
value: 0.0

304566
type: LocalParameter
value: 999999.0

304565
type: LocalParameter
value: -999999.0

705299
type: SpeciesReference
stoichiometry: 1.0
species: 302608

302608
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Formate_CH1O2

705287
type: SpeciesReference
stoichiometry: 1.0
species: 302609

303333
type: Reaction
kinetic law: 704297
product: 704285
reactant: 704273
notes: Abbreviation: R_EX_nh4_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : nh4 <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Ammonia exchange

304466
type: LocalParameter
value: 0.0

304465
type: LocalParameter
value: 0.0

304464
type: LocalParameter
value: 999999.0

304463
type: LocalParameter
value: 0.0

704285
type: SpeciesReference
stoichiometry: 1.0
species: 303051

704273
type: SpeciesReference
stoichiometry: 1.0
species: 302728

303571
type: Reaction
reactant: 711939
reactant: 711915
reactant: 711927
notes: Abbreviation: R_NNAT Synonyms: _0 EC Number: 2.7.7.18 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + h + nicrnt --> dnad + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_327#ABBREVIATION:nadD#ECNUMBERS:2.7.7.18# proteins: NAME:Nicotinic acid mononucleotide adenyltransferase#ABBREVIATION:NadD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_327)
kinetic law: 711975
reversible: false
product: 711963
name: nicotinate-nucleotide adenylyltransferase
product: 711951
fast: false

711939
type: SpeciesReference
stoichiometry: 1.0
species: 302729

302729
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Nicotinate D-ribonucleotide_C11H12NO9P

711915
type: SpeciesReference
stoichiometry: 1.0
species: 302526

711927
type: SpeciesReference
stoichiometry: 1.0
species: 302659

304993
type: LocalParameter
value: 0.0

304992
type: LocalParameter
value: 0.0

304991
type: LocalParameter
value: 999999.0

304989
type: LocalParameter
value: 0.0

711963
type: SpeciesReference
stoichiometry: 1.0
species: 302865

711951
type: SpeciesReference
stoichiometry: 1.0
species: 302580

303586
type: Reaction
kinetic law: 712388
fast: false
notes: Abbreviation: R_NTD4 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : cmp + h2o --> cytd + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 712364
reactant: 712339
reactant: 712352
name: _5'-nucleotidase (CMP)
product: 712376
reversible: false

305023
type: LocalParameter
value: 0.0

305022
type: LocalParameter
value: 0.0

305021
type: LocalParameter
value: 999999.0

305020
type: LocalParameter
value: 0.0

712364
type: SpeciesReference
stoichiometry: 1.0
species: 302546

712339
type: SpeciesReference
stoichiometry: 1.0
species: 302534

712352
type: SpeciesReference
stoichiometry: 1.0
species: 302655

712376
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stoichiometry: 1.0
species: 302853

302442
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: C'-(3-Indolyl)-glycerol 3-phosphate_C11H12NO6P

303297
type: Reaction
kinetic law: 703641
product: 703629
reactant: 703617
notes: Abbreviation: R_EX_fum_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : fum <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Fumarate exchange

304384
type: LocalParameter
value: 0.0

304383
type: LocalParameter
value: 0.0

304382
type: LocalParameter
value: 999999.0

304381
type: LocalParameter
value: 0.0

703629
type: SpeciesReference
stoichiometry: 1.0
species: 303023

703617
type: SpeciesReference
stoichiometry: 1.0
species: 302618

303224
type: Reaction
kinetic law: 701476
name: deoxyguanylate kinase (dGMP:ATP)
product: 701464
reactant: 701440
fast: false
product: 701452
reversible: true
notes: Abbreviation: R_DGK1 Synonyms: _0 EC Number: 2.7.4.8 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dgmp <==> adp + dgdp Confidence Level: 2 Added EC- JLR genes: LOCUS:BLBBGE_298#ABBREVIATION:gmk#ECNUMBERS:2.7.4.8# proteins: NAME:Guanylate kinase#ABBREVIATION:Gmk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_298)
reactant: 701428

304208
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value: 0.0

304207
type: LocalParameter
value: 0.0

304206
type: LocalParameter
value: 999999.0

304205
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value: -999999.0

701464
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stoichiometry: 1.0
species: 302561

701440
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stoichiometry: 1.0
species: 302562

302562
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dGMP_C10H12N5O7P

701452
type: SpeciesReference
stoichiometry: 1.0
species: 302493

701428
type: SpeciesReference
stoichiometry: 1.0
species: 302526

303607
type: Reaction
fast: false
product: 713104
reactant: 713080
name: Nucleoside triphosphate pyrophosphorylase (atp)
product: 713092
product: 713116
notes: Abbreviation: R_NTPP6 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + h2o --> amp + h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
reactant: 713068
kinetic law: 713128
reversible: false

713104
type: SpeciesReference
stoichiometry: 1.0
species: 302659

713080
type: SpeciesReference
stoichiometry: 1.0
species: 302655

713092
type: SpeciesReference
stoichiometry: 1.0
species: 302511

713116
type: SpeciesReference
stoichiometry: 1.0
species: 302865

713068
type: SpeciesReference
stoichiometry: 1.0
species: 302526

305071
type: LocalParameter
value: 0.0

305070
type: LocalParameter
value: 0.0

305069
type: LocalParameter
value: 999999.0

305068
type: LocalParameter
value: 0.0

303743
type: Reaction
reactant: 718661
reactant: 718637
notes: Abbreviation: R_SHK3Dr Synonyms: _0 EC Number: 1.1.1.25 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : 3dhsk + h + nadph <==> nadp + skm Confidence Level: 2 JLR- added reversible form of SHK3D genes: LOCUS:BLBBGE_142#ABBREVIATION:ydiB#ECNUMBERS:1.1.1.25# proteins: NAME:putative shikimate 5-dehydrogenase#ABBREVIATION:YdiB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_142)
product: 718673
reactant: 718649
fast: false
kinetic law: 718697
name: shikimate dehydrogenase
product: 718685
reversible: true

718661
type: SpeciesReference
stoichiometry: 1.0
species: 302724

718637
type: SpeciesReference
stoichiometry: 1.0
species: 302440

718673
type: SpeciesReference
stoichiometry: 1.0
species: 302723

718649
type: SpeciesReference
stoichiometry: 1.0
species: 302659

305580
type: LocalParameter
value: 0.0

305579
type: LocalParameter
value: 0.0

305578
type: LocalParameter
value: 999999.0

305577
type: LocalParameter
value: -999999.0

718685
type: SpeciesReference
stoichiometry: 1.0
species: 302910

303626
type: Reaction
notes: Abbreviation: R_OMBZLM Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 2ombzl + amet --> 2ommbl + ahcys + h Confidence Level: 2 JLR genes: LOCUS:BLBBGE_110#ABBREVIATION:ubiE#ECNUMBERS:2.1.1.-# proteins: NAME:_2-DMK methyltransferase and 2-octaprenyl-6-methoxy-1,4-benzoquinonol methylase#ABBREVIATION:UbiE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_110)
reactant: 713648
product: 713660
name: _2-Octaprenyl-6-methoxy-benzoquinol methylase
product: 713684
product: 713672
reversible: false
reactant: 713635
kinetic law: 713696
fast: false

713648
type: SpeciesReference
stoichiometry: 1.0
species: 302509

302509
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: S-Adenosyl-L-methionine_C15H23N6O5S

713660
type: SpeciesReference
stoichiometry: 1.0
species: 302430

302430
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Octaprenyl-3-methyl-6-methoxy- 1,4-benzoquinol_C48H74O3

713684
type: SpeciesReference
stoichiometry: 1.0
species: 302659

713672
type: SpeciesReference
stoichiometry: 1.0
species: 302495

713635
type: SpeciesReference
stoichiometry: 1.0
species: 302428

302428
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Octaprenyl-6-methoxy-1,4-benzoquinol_C47H72O3

305211
type: LocalParameter
value: 0.0

305210
type: LocalParameter
value: 0.0

305209
type: LocalParameter
value: 999999.0

305208
type: LocalParameter
value: 0.0

302988
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Urea_CH4N2O

303559
type: Reaction
fast: false
name: nucleoside-diphosphate kinase (ATP:dUDP)
kinetic law: 711614
notes: Abbreviation: R_NDPK6 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dudp <==> adp + dutp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions. genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)
reactant: 711566
product: 711590
reactant: 711578
reversible: true
product: 711602

304965
type: LocalParameter
value: 0.0

304964
type: LocalParameter
value: 0.0

304963
type: LocalParameter
value: 999999.0

304962
type: LocalParameter
value: -999999.0

711566
type: SpeciesReference
stoichiometry: 1.0
species: 302526

711590
type: SpeciesReference
stoichiometry: 1.0
species: 302493

711578
type: SpeciesReference
stoichiometry: 1.0
species: 302587

711602
type: SpeciesReference
stoichiometry: 1.0
species: 302591

302870
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _1-(5-Phosphoribosyl)-AMP_C15H19N5O14P2

303165
type: Reaction
fast: false
reactant: 698848
kinetic law: 698897
notes: Abbreviation: R_BPNT Synonyms: _0 EC Number: 3.1.3.7 SUBSYSTEM: Cysteine Metabolism Equation: [c] : h2o + pap --> amp + pi Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 698885
product: 698872
reactant: 698860
reversible: false
name: _3',5'-bisphosphate nucleotidase

698848
type: SpeciesReference
stoichiometry: 1.0
species: 302655

304062
type: LocalParameter
value: 0.0

304061
type: LocalParameter
value: 0.0

304060
type: LocalParameter
value: 999999.0

304059
type: LocalParameter
value: 0.0

698885
type: SpeciesReference
stoichiometry: 1.0
species: 302853

698872
type: SpeciesReference
stoichiometry: 1.0
species: 302511

698860
type: SpeciesReference
stoichiometry: 1.0
species: 302754

302517
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Arginine_C6H15N4O2

303777
type: Reaction
reversible: false
product: 720535
name: tryptophan synthase (indoleglycerol phosphate)
notes: Abbreviation: R_TRPS1 Synonyms: _0 EC Number: 4.2.1.20 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : 3ig3p + ser-L --> g3p + h2o + trp-L Confidence Level: 2 genes: LOCUS:BLBBGE_426#ABBREVIATION:trpA#ECNUMBERS:4.2.1.20# LOCUS:BLBBGE_425#ABBREVIATION:trpB#ECNUMBERS:4.2.1.20# proteins: NAME:Tryptophan synthase#ABBREVIATION:TrpA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_426 and BLBBGE_425)
product: 720523
product: 720547
reactant: 720511
fast: false
kinetic law: 720559
reactant: 720499

720535
type: SpeciesReference
stoichiometry: 1.0
species: 302655

720523
type: SpeciesReference
stoichiometry: 1.0
species: 302620

720547
type: SpeciesReference
stoichiometry: 1.0
species: 302950

720511
type: SpeciesReference
stoichiometry: 1.0
species: 302905

305711
type: LocalParameter
value: 0.0

305710
type: LocalParameter
value: 0.0

305709
type: LocalParameter
value: 999999.0

305708
type: LocalParameter
value: 0.0

720499
type: SpeciesReference
stoichiometry: 1.0
species: 302442

303611
type: Reaction
name: Nucleoside triphosphate pyrophosphorylase (utp)
product: 713262
kinetic law: 713274
product: 713249
reactant: 713213
notes: Abbreviation: R_NTPP8 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : h2o + utp --> h + ppi + ump Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
reversible: false
fast: false
reactant: 713225
product: 713237

713262
type: SpeciesReference
stoichiometry: 1.0
species: 302980

305173
type: LocalParameter
value: 0.0

305172
type: LocalParameter
value: 0.0

305171
type: LocalParameter
value: 999999.0

305170
type: LocalParameter
value: 0.0

713249
type: SpeciesReference
stoichiometry: 1.0
species: 302865

713213
type: SpeciesReference
stoichiometry: 1.0
species: 302655

713225
type: SpeciesReference
stoichiometry: 1.0
species: 302990

713237
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303563
type: Reaction
notes: Abbreviation: R_NDPK8 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dadp <==> adp + datp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions. genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)
name: nucleoside-diphosphate kinase (ATP:dADP)
reversible: true
product: 711723
kinetic law: 711735
reactant: 711687
product: 711711
fast: false
reactant: 711699

711723
type: SpeciesReference
stoichiometry: 1.0
species: 302551

304975
type: LocalParameter
value: 0.0

304974
type: LocalParameter
value: 0.0

304973
type: LocalParameter
value: 999999.0

304971
type: LocalParameter
value: -999999.0

711687
type: SpeciesReference
stoichiometry: 1.0
species: 302526

711711
type: SpeciesReference
stoichiometry: 1.0
species: 302493

711699
type: SpeciesReference
stoichiometry: 1.0
species: 302548

303124
type: Reaction
reactant: 696700
fast: false
reactant: 696688
name: _2-Oxogluterate dehydrogenase
kinetic law: 696760
reactant: 696712
product: 696736
product: 696748
product: 696724
notes: Abbreviation: R_AKGDH Synonyms: _0 SUBSYSTEM: Citric Acid Cycle Equation: [c] : akg + coa + nad --> co2 + nadh + succoa Confidence Level: 2 Changed from TEST_AKGDH genes: LOCUS:BLBBGE_147#ABBREVIATION:lpd#ECNUMBERS:1.8.1.4# LOCUS:BLBBGE_214#ABBREVIATION:lpd#ECNUMBERS:1.8.1.4# LOCUS:BLBBGE_597#ABBREVIATION:sucA#ECNUMBERS:1.2.4.2# LOCUS:BLBBGE_596#ABBREVIATION:sucB#ECNUMBERS:2.3.1.61# LOCUS:BLBBGE_009#ABBREVIATION:sucB#ECNUMBERS:2.3.1.61# proteins: NAME:a-ketoglutarate, B#ABBREVIATION:SucB# NAME:a-ketoglutarate, B#ABBREVIATION:SucB# NAME:a-ketoglutarate dehydrogenase, A#ABBREVIATION:SucA# NAME:dihydrolipoamide dehydrogenase#ABBREVIATION:LpdA# NAME:dihydrolipoamide dehydrogenase#ABBREVIATION:LpdA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_596) or (BLBBGE_009) and (BLBBGE_147) or (BLBBGE_214) and (BLBBGE_597)
reversible: false

696700
type: SpeciesReference
stoichiometry: 1.0
species: 302538

696688
type: SpeciesReference
stoichiometry: 1.0
species: 302500

303954
type: LocalParameter
value: 0.0

303953
type: LocalParameter
value: 0.0

303952
type: LocalParameter
value: 999999.0

303951
type: LocalParameter
value: 0.0

696712
type: SpeciesReference
stoichiometry: 1.0
species: 302719

696736
type: SpeciesReference
stoichiometry: 1.0
species: 302720

696748
type: SpeciesReference
stoichiometry: 1.0
species: 302928

696724
type: SpeciesReference
stoichiometry: 1.0
species: 302536

303229
type: Reaction
fast: false
notes: Abbreviation: R_DHDPRy Synonyms: _0 EC Number: 1.3.1.26 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : 23dhdp + h + nadph --> nadp + thdp Confidence Level: 2 genes: LOCUS:BLBBGE_551#ABBREVIATION:dapB#ECNUMBERS:1.3.1.26# proteins: NAME:Dihydrodipicolinate reductase#ABBREVIATION:DapB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_551)
kinetic law: 701648
reactant: 701587
reactant: 701599
reversible: false
name: dihydrodipicolinate reductase (NADPH)
product: 701624
reactant: 701611
product: 701636

304222
type: LocalParameter
value: 0.0

304221
type: LocalParameter
value: 0.0

304220
type: LocalParameter
value: 999999.0

304219
type: LocalParameter
value: 0.0

701587
type: SpeciesReference
stoichiometry: 1.0
species: 302410

701599
type: SpeciesReference
stoichiometry: 1.0
species: 302659

701624
type: SpeciesReference
stoichiometry: 1.0
species: 302723

701611
type: SpeciesReference
stoichiometry: 1.0
species: 302724

701636
type: SpeciesReference
stoichiometry: 1.0
species: 302933

302933
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2,3,4,5-Tetrahydrodipicolinate_C7H7NO4

303010
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Aspartate_C4H6NO4

303188
type: Reaction
reactant: 700007
fast: false
product: 700019
product: 700043
notes: Abbreviation: R_CS Synonyms: _0 SUBSYSTEM: Citric Acid Cycle Equation: [c] : accoa + h2o + oaa --> cit + coa + h Confidence Level: 2 old EC number (4.1.3.7) is obsolete -- transferred to 2.3.3.1 genes: LOCUS:BLBBGE_540#ABBREVIATION:gltA#ECNUMBERS:2.3.3.1# proteins: NAME:citrate synthase#ABBREVIATION:GltA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_540)
reversible: false
name: citrate synthase
reactant: 699983
kinetic law: 700055
product: 700031
reactant: 699995

700007
type: SpeciesReference
stoichiometry: 1.0
species: 302738

700019
type: SpeciesReference
stoichiometry: 1.0
species: 302532

700043
type: SpeciesReference
stoichiometry: 1.0
species: 302659

699983
type: SpeciesReference
stoichiometry: 1.0
species: 302479

304120
type: LocalParameter
value: 0.0

304119
type: LocalParameter
value: 0.0

304118
type: LocalParameter
value: 999999.0

304117
type: LocalParameter
value: 0.0

700031
type: SpeciesReference
stoichiometry: 1.0
species: 302538

699995
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303389
type: Reaction
product: 705580
product: 705593
reactant: 705542
reactant: 705554
fast: false
kinetic law: 705605
name: glucosamine-1-phosphate N-acetyltransferase
notes: Abbreviation: R_G1PACT Synonyms: _0 EC Number: 2.3.1.157 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : accoa + gam1p --> acgam1p + coa + h Confidence Level: 2 genes: LOCUS:BLBBGE_605#ABBREVIATION:galU#ECNUMBERS:2.7.7.23# proteins: NAME:UTP-glucose-1-phosphate uridylyltransferase#ABBREVIATION:galU# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_605)
reversible: false
product: 705567

705580
type: SpeciesReference
stoichiometry: 1.0
species: 302538

705593
type: SpeciesReference
stoichiometry: 1.0
species: 302659

705542
type: SpeciesReference
stoichiometry: 1.0
species: 302479

705554
type: SpeciesReference
stoichiometry: 1.0
species: 302621

304590
type: LocalParameter
value: 0.0

304589
type: LocalParameter
value: 0.0

304588
type: LocalParameter
value: 999999.0

304587
type: LocalParameter
value: 0.0

705567
type: SpeciesReference
stoichiometry: 1.0
species: 302483

302483
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-Acetyl-D-glucosamine 1-phosphate_C8H14NO9P

303590
type: Reaction
name: _5'-nucleotidase (dAMP)
reactant: 712461
reversible: false
fast: false
product: 712499
reactant: 712474
kinetic law: 712511
product: 712486
notes: Abbreviation: R_NTD6 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : damp + h2o --> dad-2 + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:

712461
type: SpeciesReference
stoichiometry: 1.0
species: 302550

712499
type: SpeciesReference
stoichiometry: 1.0
species: 302853

712474
type: SpeciesReference
stoichiometry: 1.0
species: 302655

305033
type: LocalParameter
value: 0.0

305032
type: LocalParameter
value: 0.0

305031
type: LocalParameter
value: 999999.0

305029
type: LocalParameter
value: 0.0

712486
type: SpeciesReference
stoichiometry: 1.0
species: 302547

303769
type: Reaction
reversible: false
name: thiamine diphosphokinase
reactant: 720126
product: 720150
product: 720174
product: 720162
notes: Abbreviation: R_TMDPK Synonyms: _0 EC Number: 2.7.6.2 SUBSYSTEM: Thiamine Metabolism Equation: [c] : atp + thm --> amp + h + thmpp Confidence Level: 2 genes: LOCUS:BLBBGE_618#ABBREVIATION:thiN#ECNUMBERS:2.7.6.2# proteins: NAME:thiamin pyrophosphokinase 1#ABBREVIATION:ThiN# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_618)
fast: false
reactant: 720138
kinetic law: 720186

720126
type: SpeciesReference
stoichiometry: 1.0
species: 302526

720150
type: SpeciesReference
stoichiometry: 1.0
species: 302511

720174
type: SpeciesReference
stoichiometry: 1.0
species: 302939

720162
type: SpeciesReference
stoichiometry: 1.0
species: 302659

720138
type: SpeciesReference
stoichiometry: 1.0
species: 302935

305681
type: LocalParameter
value: 0.0

305680
type: LocalParameter
value: 0.0

305679
type: LocalParameter
value: 999999.0

305678
type: LocalParameter
value: 0.0

303702
type: Reaction
kinetic law: 716561
product: 716537
fast: false
reversible: false
notes: Abbreviation: R_PSD_Bge Synonyms: _0 EC Number: 4.1.1.65 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : h + (0.02) ps_Bge --> co2 + (0.02) pe_Bge Confidence Level: 2 JLR genes: LOCUS:BLBBGE_225#ABBREVIATION:psd#ECNUMBERS:4.1.1.65# proteins: NAME:Phosphatidylserine decarboxylase#ABBREVIATION:Psd# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_225)
reactant: 716513
reactant: 716525
product: 716549
name: Phosphatidylserine decarboxylase

305418
type: LocalParameter
value: 0.0

305417
type: LocalParameter
value: 0.0

305416
type: LocalParameter
value: 999999.0

305415
type: LocalParameter
value: 0.0

716537
type: SpeciesReference
stoichiometry: 1.0
species: 302536

716513
type: SpeciesReference
stoichiometry: 1.0
species: 302659

716525
type: SpeciesReference
stoichiometry: 0.02
species: 302883

716549
type: SpeciesReference
stoichiometry: 0.02
species: 302759

303803
type: Reaction
kinetic law: 721997
product: 721985
reactant: 721973
notes: Abbreviation: R_UREAt Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: urea[e] <==> urea[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_460#ABBREVIATION:glpF# proteins: NAME:MIP channel, glycerol diffusion#ABBREVIATION:GlpF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_460)
fast: false
reversible: true
name: Urea transport via facilitate diffusion

305809
type: LocalParameter
value: 0.0

305808
type: LocalParameter
value: 0.0

305807
type: LocalParameter
value: 999999.0

305806
type: LocalParameter
value: -999999.0

721985
type: SpeciesReference
stoichiometry: 1.0
species: 302985

721973
type: SpeciesReference
stoichiometry: 1.0
species: 302988

302472
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _Mevalonate-5-phosphate_C6H10O7P

303099
type: Reaction
name: _4-amino-4-deoxychorismate synthase
product: 695759
notes: Abbreviation: R_ADCS Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : chor + gln-L --> 4adcho + glu-L Confidence Level: 2 Not in IUBMB. No EC genes: LOCUS:BLBBGE_421#ABBREVIATION:trpE#ECNUMBERS:6.3.5.8# LOCUS:BLBBGE_422#ABBREVIATION:trpD#ECNUMBERS:6.3.5.8# proteins: NAME:p-aminobenzoate synthetase, component II#ABBREVIATION:TrpD# NAME:p-aminobenzoate synthetase, component I#ABBREVIATION:TrpE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_421) and (BLBBGE_422)
kinetic law: 695771
reactant: 695723
product: 695747
reactant: 695735
reversible: false
fast: false

695759
type: SpeciesReference
stoichiometry: 1.0
species: 302633

303882
type: LocalParameter
value: 0.0

303881
type: LocalParameter
value: 0.0

303880
type: LocalParameter
value: 999999.0

303879
type: LocalParameter
value: 0.0

695723
type: SpeciesReference
stoichiometry: 1.0
species: 302531

695747
type: SpeciesReference
stoichiometry: 1.0
species: 302451

695735
type: SpeciesReference
stoichiometry: 1.0
species: 302628

303057
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: (R)-Pantothenate_C9H16NO5

302569
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _1,4-Dihydroxy-2-naphthoate_C11H7O4

303135
type: Reaction
kinetic law: 697201
notes: Abbreviation: R_AMMQLT8 Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 2dmmql8 + amet --> ahcys + h + mql8 Confidence Level: 2 AMF genes: LOCUS:BLBBGE_110#ABBREVIATION:ubiE#ECNUMBERS:2.1.1.-# proteins: NAME:_2-DMK methyltransferase and 2-octaprenyl-6-methoxy-1,4-benzoquinonol methylase#ABBREVIATION:UbiE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_110)
reversible: false
product: 697164
name: S-adenosylmethione:2-demthylmenaquinole methyltransferase (menaquinone 8)
reactant: 697152
product: 697176
reactant: 697140
product: 697188
fast: false

303986
type: LocalParameter
value: 0.0

303985
type: LocalParameter
value: 0.0

303984
type: LocalParameter
value: 999999.0

303983
type: LocalParameter
value: 0.0

697164
type: SpeciesReference
stoichiometry: 1.0
species: 302495

697152
type: SpeciesReference
stoichiometry: 1.0
species: 302509

697176
type: SpeciesReference
stoichiometry: 1.0
species: 302659

697140
type: SpeciesReference
stoichiometry: 1.0
species: 302423

697188
type: SpeciesReference
stoichiometry: 1.0
species: 302709

303478
type: Reaction
reversible: false
product: 708625
product: 708637
reactant: 708601
notes: Abbreviation: R_IPMD Synonyms: _0 EC Number: 1.1.1.85 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 3c2hmp + nad --> 3c4mop + h + nadh Confidence Level: 2 genes: LOCUS:BLBBGE_070#ABBREVIATION:leuB#ECNUMBERS:1.1.1.85# proteins: NAME:Isopropylmalate dehydrogenase#ABBREVIATION:LeuB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_070)
product: 708613
fast: false
kinetic law: 708650
name: _3-isopropylmalate dehydrogenase
reactant: 708589

708625
type: SpeciesReference
stoichiometry: 1.0
species: 302659

708637
type: SpeciesReference
stoichiometry: 1.0
species: 302720

708601
type: SpeciesReference
stoichiometry: 1.0
species: 302719

708613
type: SpeciesReference
stoichiometry: 1.0
species: 302437

304781
type: LocalParameter
value: 0.0

304780
type: LocalParameter
value: 0.0

304779
type: LocalParameter
value: 999999.0

304778
type: LocalParameter
value: 0.0

708589
type: SpeciesReference
stoichiometry: 1.0
species: 302435

302455
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _4-Phospho-L-aspartate_C4H6NO7P

302408
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Phospho-D-glyceroyl phosphate_C3H4O10P2

303398
type: Reaction
notes: Abbreviation: R_GCALDD Synonyms: _0 EC Number: 1.2.1.21 SUBSYSTEM: Folate Metabolism Equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 705895
reactant: 705919
kinetic law: 705967
name: Glycolaldehyde dehydrogenase
product: 705931
reactant: 705907
fast: false
product: 705943
product: 705955
reversible: false

705895
type: SpeciesReference
stoichiometry: 1.0
species: 302625

705919
type: SpeciesReference
stoichiometry: 1.0
species: 302719

304611
type: LocalParameter
value: 0.0

304610
type: LocalParameter
value: 0.0

304609
type: LocalParameter
value: 999999.0

304608
type: LocalParameter
value: 0.0

705931
type: SpeciesReference
stoichiometry: 1.0
species: 302645

705907
type: SpeciesReference
stoichiometry: 1.0
species: 302655

705943
type: SpeciesReference
stoichiometry: 2.0
species: 302659

705955
type: SpeciesReference
stoichiometry: 1.0
species: 302720

303579
type: Reaction
reactant: 712169
product: 712193
reactant: 712157
name: _5'-nucleotidase (IMP)
notes: Abbreviation: R_NTD11 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : h2o + imp --> ins + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
kinetic law: 712205
product: 712181
reversible: false

712169
type: SpeciesReference
stoichiometry: 1.0
species: 302683

712193
type: SpeciesReference
stoichiometry: 1.0
species: 302853

712157
type: SpeciesReference
stoichiometry: 1.0
species: 302655

305011
type: LocalParameter
value: 0.0

305010
type: LocalParameter
value: 0.0

305009
type: LocalParameter
value: 999999.0

305007
type: LocalParameter
value: 0.0

712181
type: SpeciesReference
stoichiometry: 1.0
species: 302686

302718
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Nicotinate_C6H4NO2

303233
type: Reaction
name: dihydrofolate reductase
kinetic law: 701793
reactant: 701757
reactant: 701744
product: 701781
product: 701769
fast: false
notes: Abbreviation: R_DHFR Synonyms: _0 EC Number: 1.5.1.3 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : dhf + h + nadph <==> nadp + thf Confidence Level: 2 The enzyme from animals and some micro-organisms also slowly reduces folate to 5,6,7,8-tetrahydrofolate genes: LOCUS:BLBBGE_449#ABBREVIATION:folA#ECNUMBERS:1.5.1.3# proteins: NAME:dihydrofolate reductase#ABBREVIATION:FolA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_449)
reversible: true
reactant: 701732

304230
type: LocalParameter
value: 0.0

304229
type: LocalParameter
value: 0.0

304228
type: LocalParameter
value: 999999.0

304227
type: LocalParameter
value: -999999.0

701757
type: SpeciesReference
stoichiometry: 1.0
species: 302724

701744
type: SpeciesReference
stoichiometry: 1.0
species: 302659

701781
type: SpeciesReference
stoichiometry: 1.0
species: 302934

701769
type: SpeciesReference
stoichiometry: 1.0
species: 302723

701732
type: SpeciesReference
stoichiometry: 1.0
species: 302567

303334
type: Reaction
kinetic law: 704333
product: 704321
reactant: 704309
notes: Abbreviation: R_EX_o2_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : o2 <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: O2 exchange

304470
type: LocalParameter
value: 0.0

304469
type: LocalParameter
value: 0.0

304468
type: LocalParameter
value: 0.0

304467
type: LocalParameter
value: -999999.0

704321
type: SpeciesReference
stoichiometry: 1.0
species: 303052

303052
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: O2_O2

704309
type: SpeciesReference
stoichiometry: 1.0
species: 302734

302734
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: O2_O2

303199
type: Reaction
fast: false
name: cytidine deaminase
reactant: 700607
product: 700631
kinetic law: 700643
notes: Abbreviation: R_CYTD Synonyms: _0 EC Number: 3.5.4.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : cytd + h + h2o --> nh4 + uri Confidence Level: 2 genes: LOCUS:BLBBGE_495#ABBREVIATION:cdd#ECNUMBERS:3.5.4.5# proteins: NAME:cytidine/deoxycytidine deaminase#ABBREVIATION:Cdd# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_495)
reactant: 700595
product: 700619
reversible: false
reactant: 700583

700607
type: SpeciesReference
stoichiometry: 1.0
species: 302655

700631
type: SpeciesReference
stoichiometry: 1.0
species: 302989

304152
type: LocalParameter
value: 0.0

304151
type: LocalParameter
value: 0.0

304150
type: LocalParameter
value: 999999.0

304148
type: LocalParameter
value: 0.0

700595
type: SpeciesReference
stoichiometry: 1.0
species: 302659

700619
type: SpeciesReference
stoichiometry: 1.0
species: 302725

700583
type: SpeciesReference
stoichiometry: 1.0
species: 302546

302552
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3,4-dihydroxy-2-butanone 4-phosphate_C4H7O6P

303252
type: Reaction
fast: false
notes: Abbreviation: R_DNMPPA Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : dhpmp + h2o --> dhnpt + pi Confidence Level: 1 JLR- Neidhardt page 667 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 702422
kinetic law: 702470
product: 702458
name: Dihydroneopterin monophosphate dephosphorylase
reversible: false
product: 702446
reactant: 702434

702422
type: SpeciesReference
stoichiometry: 1.0
species: 302574

302574
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Dihydroneopterin monophosphate_C9H12N5O7P

304280
type: LocalParameter
value: 0.0

304279
type: LocalParameter
value: 0.0

304278
type: LocalParameter
value: 999999.0

304277
type: LocalParameter
value: 0.0

702458
type: SpeciesReference
stoichiometry: 1.0
species: 302853

702446
type: SpeciesReference
stoichiometry: 1.0
species: 302570

702434
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303202
type: Reaction
notes: Abbreviation: R_CYTDK2 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : cytd + gtp --> cmp + gdp + h Confidence Level: 2 genes: LOCUS:BLBBGE_535#ABBREVIATION:udk#ECNUMBERS:2.7.1.48# proteins: NAME:uridine/cytidine kinase#ABBREVIATION:Udk# citations: none GENE ASSOCIATION: (BLBBGE_535)
name: cytidine kinase (GTP)
product: 700691
reactant: 700655
fast: false
product: 700679
product: 700703
reactant: 700667
kinetic law: 700715
reversible: false

700691
type: SpeciesReference
stoichiometry: 1.0
species: 302626

700655
type: SpeciesReference
stoichiometry: 1.0
species: 302546

700679
type: SpeciesReference
stoichiometry: 1.0
species: 302534

700703
type: SpeciesReference
stoichiometry: 1.0
species: 302659

700667
type: SpeciesReference
stoichiometry: 1.0
species: 302651

304156
type: LocalParameter
value: 0.0

304155
type: LocalParameter
value: 0.0

304154
type: LocalParameter
value: 999999.0

304153
type: LocalParameter
value: 0.0

303515
type: Reaction
name: methionine adenosyltransferase
product: 710056
notes: Abbreviation: R_METAT Synonyms: _0 EC Number: 2.5.1.6 SUBSYSTEM: Methionine Metabolism Equation: [c] : atp + h2o + met-L --> amet + pi + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_345#ABBREVIATION:metK#ECNUMBERS:2.5.1.6# proteins: NAME:methionine adenosyltransferase I#ABBREVIATION:MetK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_345)
kinetic law: 710092
product: 710068
reversible: false
fast: false
reactant: 710020
reactant: 710044
product: 710080
reactant: 710032

710056
type: SpeciesReference
stoichiometry: 1.0
species: 302509

304867
type: LocalParameter
value: 0.0

304866
type: LocalParameter
value: 0.0

304865
type: LocalParameter
value: 999999.0

304864
type: LocalParameter
value: 0.0

710068
type: SpeciesReference
stoichiometry: 1.0
species: 302853

710020
type: SpeciesReference
stoichiometry: 1.0
species: 302526

710044
type: SpeciesReference
stoichiometry: 1.0
species: 302702

710080
type: SpeciesReference
stoichiometry: 1.0
species: 302865

710032
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303619
type: Reaction
product: 713479
reactant: 713443
name: ornithine carbamoyltransferase
product: 713467
reversible: false
notes: Abbreviation: R_OCBT Synonyms: _0 EC Number: 2.1.3.3 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : cbp + orn --> citr-L + h + pi Confidence Level: 2 genes: LOCUS:BLBBGE_318#ABBREVIATION:argF#ECNUMBERS:2.1.3.3# proteins: NAME:Ornithine carbamoyl transferase II#ABBREVIATION:ArgF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_318)
kinetic law: 713503
fast: false
product: 713491
reactant: 713455

713479
type: SpeciesReference
stoichiometry: 1.0
species: 302659

713443
type: SpeciesReference
stoichiometry: 1.0
species: 302527

713467
type: SpeciesReference
stoichiometry: 1.0
species: 302533

302533
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Citrulline_C6H13N3O3

305197
type: LocalParameter
value: 0.0

305195
type: LocalParameter
value: 0.0

305194
type: LocalParameter
value: 999999.0

305192
type: LocalParameter
value: 0.0

713491
type: SpeciesReference
stoichiometry: 1.0
species: 302853

713455
type: SpeciesReference
stoichiometry: 1.0
species: 302744

303796
type: Reaction
reactant: 721573
name: Undecaprenyl diphosphate synthase
reactant: 721585
kinetic law: 721621
reversible: false
fast: false
product: 721609
product: 721597
notes: Abbreviation: R_UDCPDPS Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : frdp + (8) ipdp --> (8) ppi + udcpdp Confidence Level: 2 tv genes: LOCUS:BLBBGE_087#ABBREVIATION:ispU#ECNUMBERS:2.5.1.31# proteins: NAME:Undecaprenyl diphosphate synthase#ABBREVIATION:UppS# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_087)

721573
type: SpeciesReference
stoichiometry: 1.0
species: 302613

721585
type: SpeciesReference
stoichiometry: 8.0
species: 302687

305781
type: LocalParameter
value: 0.0

305780
type: LocalParameter
value: 0.0

305779
type: LocalParameter
value: 999999.0

305778
type: LocalParameter
value: 0.0

721609
type: SpeciesReference
stoichiometry: 1.0
species: 302973

721597
type: SpeciesReference
stoichiometry: 8.0
species: 302865

303778
type: Reaction
product: 720609
reversible: false
reactant: 720584
reactant: 720572
notes: Abbreviation: R_TRPS2 Synonyms: _0 EC Number: 4.2.1.20 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : indole + ser-L --> h2o + trp-L Confidence Level: 2 A pyridoxal-phosphate protein. Also catalyses the conversion of serine and indole into tryptophan and water, and of indoleglycerol phosphate into indole and glyceraldehyde phosphate (the latter reaction was listed formerly as EC 4.1.2.8). genes: LOCUS:BLBBGE_426#ABBREVIATION:trpA#ECNUMBERS:4.2.1.20# LOCUS:BLBBGE_425#ABBREVIATION:trpB#ECNUMBERS:4.2.1.20# proteins: NAME:Tryptophan synthase#ABBREVIATION:TrpA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_426 and BLBBGE_425)
name: tryptophan synthase (indole)
product: 720597
fast: false
kinetic law: 720622

720609
type: SpeciesReference
stoichiometry: 1.0
species: 302950

720584
type: SpeciesReference
stoichiometry: 1.0
species: 302905

720572
type: SpeciesReference
stoichiometry: 1.0
species: 302684

720597
type: SpeciesReference
stoichiometry: 1.0
species: 302655

305715
type: LocalParameter
value: 0.0

305714
type: LocalParameter
value: 0.0

305713
type: LocalParameter
value: 999999.0

305712
type: LocalParameter
value: 0.0

303591
type: Reaction
name: _5'-nucleotidase (AMP)
product: 712548
product: 712560
notes: Abbreviation: R_NTD7 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : amp + h2o --> adn + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
reversible: false
fast: false
kinetic law: 712572
reactant: 712536
reactant: 712524

712548
type: SpeciesReference
stoichiometry: 1.0
species: 302492

712560
type: SpeciesReference
stoichiometry: 1.0
species: 302853

305037
type: LocalParameter
value: 0.0

305036
type: LocalParameter
value: 0.0

305035
type: LocalParameter
value: 999999.0

305034
type: LocalParameter
value: 0.0

712536
type: SpeciesReference
stoichiometry: 1.0
species: 302655

712524
type: SpeciesReference
stoichiometry: 1.0
species: 302511

302606
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: FMN_C17H19N4O9P

303482
type: Reaction
kinetic law: 708746
product: 708734
reactant: 708722
reactant: 708710
notes: Abbreviation: R_IPPMIb Synonyms: _0 EC Number: 4.2.1.33 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 2ippm + h2o <==> 3c3hmp Confidence Level: 2 Part of IPPMI (3-isopropylmalate dehydrogenase) enzyme added EC -NCD genes: LOCUS:BLBBGE_069#ABBREVIATION:leuD#ECNUMBERS:4.2.1.33,-!-,4.2.1.35# LOCUS:BLBBGE_068#ABBREVIATION:leuC#ECNUMBERS:4.2.1.33# proteins: NAME:Isopropylmalate isomerase small subunit#ABBREVIATION:LeuC# NAME:Isopropylmalate isomerase large subunit#ABBREVIATION:LeuD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_068 and BLBBGE_069)
fast: false
reversible: true
name: _2-isopropylmalate hydratase

304791
type: LocalParameter
value: 0.0

304790
type: LocalParameter
value: 0.0

304789
type: LocalParameter
value: 999999.0

304788
type: LocalParameter
value: -999999.0

708734
type: SpeciesReference
stoichiometry: 1.0
species: 302436

708722
type: SpeciesReference
stoichiometry: 1.0
species: 302655

708710
type: SpeciesReference
stoichiometry: 1.0
species: 302426

303781
type: Reaction
kinetic law: 720739
product: 720726
reactant: 720700
fast: false
reversible: true
notes: Abbreviation: R_TRPt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h[e] + trp-L[e] <==> h[c] + trp-L[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 720687
name: L-tryptophan reversible transport via proton symport
product: 720713

305726
type: LocalParameter
value: 0.0

305725
type: LocalParameter
value: 0.0

305724
type: LocalParameter
value: 999999.0

305723
type: LocalParameter
value: -999999.0

720726
type: SpeciesReference
stoichiometry: 1.0
species: 302950

720700
type: SpeciesReference
stoichiometry: 1.0
species: 302953

720687
type: SpeciesReference
stoichiometry: 1.0
species: 302660

720713
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303646
type: Reaction
fast: false
product: 714457
product: 714421
reactant: 714383
kinetic law: 714469
reactant: 714371
product: 714445
name: Pyridoxine 5'-phosphate synthase
product: 714433
product: 714396
reversible: false
notes: Abbreviation: R_PDX5PS Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : dxyl5p + nad + phthr --> co2 + h + (2) h2o + nadh + pdx5p + pi Confidence Level: 2 JLR- two reactions combined (intermediate of the first is unknown) genes: LOCUS:BLBBGE_075#ABBREVIATION:pdxA#ECNUMBERS:1.1.1.262# LOCUS:BLBBGE_015#ABBREVIATION:pdxJ# proteins: NAME:Pyridoxine 5-phosphate biosynthetic protein#ABBREVIATION:PdxAJ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_015 and BLBBGE_075)
product: 714408
reactant: 714359

714457
type: SpeciesReference
stoichiometry: 1.0
species: 302853

714421
type: SpeciesReference
stoichiometry: 2.0
species: 302655

714383
type: SpeciesReference
stoichiometry: 1.0
species: 302770

305257
type: LocalParameter
value: 0.0

305256
type: LocalParameter
value: 0.0

305255
type: LocalParameter
value: 999999.0

305254
type: LocalParameter
value: 0.0

714371
type: SpeciesReference
stoichiometry: 1.0
species: 302719

714445
type: SpeciesReference
stoichiometry: 1.0
species: 302758

714433
type: SpeciesReference
stoichiometry: 1.0
species: 302720

714396
type: SpeciesReference
stoichiometry: 1.0
species: 302536

714408
type: SpeciesReference
stoichiometry: 1.0
species: 302659

714359
type: SpeciesReference
stoichiometry: 1.0
species: 302592

303705
type: Reaction
notes: Abbreviation: R_PSP_L Synonyms: _0 EC Number: 3.1.3.3 SUBSYSTEM: Glycine and Serine Metabolism Equation: [c] : h2o + pser-L --> pi + ser-L Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 716657
kinetic law: 716681
fast: false
reactant: 716645
reactant: 716633
product: 716669
reversible: false
name: phosphoserine phosphatase (L-serine)

716657
type: SpeciesReference
stoichiometry: 1.0
species: 302853

305429
type: LocalParameter
value: 0.0

305428
type: LocalParameter
value: 0.0

305427
type: LocalParameter
value: 999999.0

305426
type: LocalParameter
value: 0.0

716645
type: SpeciesReference
stoichiometry: 1.0
species: 302884

302884
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: O-Phospho-L-serine_C3H6NO6P

716633
type: SpeciesReference
stoichiometry: 1.0
species: 302655

716669
type: SpeciesReference
stoichiometry: 1.0
species: 302905

303342
type: Reaction
kinetic law: 704480
product: 704468
reactant: 704456
notes: Abbreviation: R_EX_ppbng_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : ppbng <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Porphobilinogen exchange

304488
type: LocalParameter
value: 0.0

304487
type: LocalParameter
value: 0.0

304486
type: LocalParameter
value: 999999.0

304485
type: LocalParameter
value: -999999.0

704468
type: SpeciesReference
stoichiometry: 1.0
species: 303060

704456
type: SpeciesReference
stoichiometry: 1.0
species: 302863

303583
type: Reaction
kinetic law: 712327
product: 712315
reversible: false
reactant: 712291
name: _5'-nucleotidase (dCMP)
reactant: 712279
product: 712303
notes: Abbreviation: R_NTD3 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dcmp + h2o --> dcyt + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false

305019
type: LocalParameter
value: 0.0

305018
type: LocalParameter
value: 0.0

305017
type: LocalParameter
value: 999999.0

305016
type: LocalParameter
value: 0.0

712315
type: SpeciesReference
stoichiometry: 1.0
species: 302853

712291
type: SpeciesReference
stoichiometry: 1.0
species: 302655

712279
type: SpeciesReference
stoichiometry: 1.0
species: 302556

712303
type: SpeciesReference
stoichiometry: 1.0
species: 302559

302559
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Deoxycytidine_C9H13N3O4

303598
type: Reaction
reactant: 712716
fast: false
product: 712740
notes: Abbreviation: R_NTPP1 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dgtp + h2o --> dgmp + h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
reactant: 712704
kinetic law: 712765
name: Nucleoside triphosphate pyrophosphorylase (dgtp)
product: 712728
reversible: false
product: 712753

712716
type: SpeciesReference
stoichiometry: 1.0
species: 302655

712740
type: SpeciesReference
stoichiometry: 1.0
species: 302659

712704
type: SpeciesReference
stoichiometry: 1.0
species: 302565

305049
type: LocalParameter
value: 0.0

305048
type: LocalParameter
value: 0.0

305047
type: LocalParameter
value: 999999.0

305046
type: LocalParameter
value: 0.0

712728
type: SpeciesReference
stoichiometry: 1.0
species: 302562

712753
type: SpeciesReference
stoichiometry: 1.0
species: 302865

303244
type: Reaction
product: 702217
reversible: false
fast: false
reactant: 702205
name: dihydropteroate synthase
notes: Abbreviation: R_DHPS2 Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 4abz + 6hmhptpp --> dhpt + h + ppi Confidence Level: 2 JLR- similar to DHPS except uses 6hmhptpp (has ketone rather than OH) genes: LOCUS:BLBBGE_102#ABBREVIATION:folP#ECNUMBERS:2.5.1.15# proteins: NAME:Dihydropteroate synthase#ABBREVIATION:FolP# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_102)
reactant: 702192
kinetic law: 702253
product: 702229
product: 702241

702217
type: SpeciesReference
stoichiometry: 1.0
species: 302575

702205
type: SpeciesReference
stoichiometry: 1.0
species: 302474

302474
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _6-hydroxymethyl-dihydropterin pyrophosphate_C7H8N5O8P2

702192
type: SpeciesReference
stoichiometry: 1.0
species: 302450

304262
type: LocalParameter
value: 0.0

304261
type: LocalParameter
value: 0.0

304260
type: LocalParameter
value: 999999.0

304259
type: LocalParameter
value: 0.0

702229
type: SpeciesReference
stoichiometry: 1.0
species: 302659

702241
type: SpeciesReference
stoichiometry: 1.0
species: 302865

303261
type: Reaction
reversible: false
product: 702795
product: 702807
kinetic law: 702831
fast: false
notes: Abbreviation: R_DURIK1 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + duri --> adp + dump + h Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
name: deoxyuridine kinase (ATP:Deoxyuridine)
reactant: 702783
product: 702819
reactant: 702771

702795
type: SpeciesReference
stoichiometry: 1.0
species: 302493

702807
type: SpeciesReference
stoichiometry: 1.0
species: 302588

304304
type: LocalParameter
value: 0.0

304303
type: LocalParameter
value: 0.0

304302
type: LocalParameter
value: 999999.0

304300
type: LocalParameter
value: 0.0

702783
type: SpeciesReference
stoichiometry: 1.0
species: 302589

702819
type: SpeciesReference
stoichiometry: 1.0
species: 302659

702771
type: SpeciesReference
stoichiometry: 1.0
species: 302526

303144
type: Reaction
kinetic law: 697580
reactant: 697532
notes: Abbreviation: R_ARGDC Synonyms: _0 EC Number: 4.1.1.19 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : arg-L + h --> agm + co2 Confidence Level: 2 genes: LOCUS:BLBBGE_060#ABBREVIATION:speA#ECNUMBERS:4.1.1.19# proteins: NAME:Arginine decarboxylase#ABBREVIATION:SpeA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_060)
name: arginine decarboxylase
reactant: 697544
fast: false
product: 697568
product: 697556
reversible: false

304008
type: LocalParameter
value: 0.0

304007
type: LocalParameter
value: 0.0

304006
type: LocalParameter
value: 999999.0

304005
type: LocalParameter
value: 0.0

697532
type: SpeciesReference
stoichiometry: 1.0
species: 302516

697544
type: SpeciesReference
stoichiometry: 1.0
species: 302659

697568
type: SpeciesReference
stoichiometry: 1.0
species: 302536

697556
type: SpeciesReference
stoichiometry: 1.0
species: 302494

303443
type: Reaction
product: 707521
name: histidinol-phosphatase
product: 707509
reactant: 707485
notes: Abbreviation: R_HISTP Synonyms: _0 EC Number: 3.1.3.15 SUBSYSTEM: Histidine Metabolism Equation: [c] : h2o + hisp --> histd + pi Confidence Level: 2 genes: LOCUS:BLBBGE_436#ABBREVIATION:hisB#ECNUMBERS:3.1.3.15,-!-,4.2.1.19# proteins: NAME:Imidazoleglycerol phosphate dehydratase and Histidinol phosphatase#ABBREVIATION:HisB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_436)
reactant: 707497
kinetic law: 707533
reversible: false
fast: false

707521
type: SpeciesReference
stoichiometry: 1.0
species: 302853

707509
type: SpeciesReference
stoichiometry: 1.0
species: 302670

707485
type: SpeciesReference
stoichiometry: 1.0
species: 302655

707497
type: SpeciesReference
stoichiometry: 1.0
species: 302668

302668
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Histidinol phosphate_C6H11N3O4P

304709
type: LocalParameter
value: 0.0

304708
type: LocalParameter
value: 0.0

304707
type: LocalParameter
value: 999999.0

304706
type: LocalParameter
value: 0.0

303507
type: Reaction
notes: Abbreviation: R_MCOATA Synonyms: _2 EC Number: 2.3.1.39 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : ACP + malcoa --> coa + malACP Confidence Level: 2 tv genes: LOCUS:BLBBGE_538#ABBREVIATION:fabD#ECNUMBERS:2.3.1.39# proteins: NAME:Malonyl coenzyme A-acyl carrier protein transacylase#ABBREVIATION:FabD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_538)
fast: false
reactant: 709727
reversible: false
kinetic law: 709764
name: Malonyl-CoA-ACP transacylase
reactant: 709715
product: 709739
product: 709752

709727
type: SpeciesReference
stoichiometry: 1.0
species: 302701

304849
type: LocalParameter
value: 0.0

304848
type: LocalParameter
value: 0.0

304847
type: LocalParameter
value: 999999.0

304846
type: LocalParameter
value: 0.0

709715
type: SpeciesReference
stoichiometry: 1.0
species: 302487

709739
type: SpeciesReference
stoichiometry: 1.0
species: 302538

709752
type: SpeciesReference
stoichiometry: 1.0
species: 302697

303249
type: Reaction
product: 702397
name: dimethylallyltranstransferase
reactant: 702361
fast: false
notes: Abbreviation: R_DMATT Synonyms: _0 EC Number: 2.5.1.1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : dmpp + ipdp --> grdp + ppi Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
kinetic law: 702410
reactant: 702373
reversible: false
product: 702385

702397
type: SpeciesReference
stoichiometry: 1.0
species: 302865

702361
type: SpeciesReference
stoichiometry: 1.0
species: 302579

304276
type: LocalParameter
value: 0.0

304275
type: LocalParameter
value: 0.0

304274
type: LocalParameter
value: 999999.0

304273
type: LocalParameter
value: 0.0

702373
type: SpeciesReference
stoichiometry: 1.0
species: 302687

702385
type: SpeciesReference
stoichiometry: 1.0
species: 302649

303786
type: Reaction
notes: Abbreviation: R_UAGAAT Synonyms: _0 EC Number: 2.3.1.129 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : 3hmrsACP + uacgam <==> ACP + u3aga Confidence Level: 1 JLR- NH page 1041 genes: none proteins: none citations: none GENE ASSOCIATION:
name: UDP-N-acetylglucosamine acyltransferase
reactant: 720968
product: 720992
kinetic law: 721016
reactant: 720980
reversible: true
product: 721004
fast: false

720968
type: SpeciesReference
stoichiometry: 1.0
species: 302441

720992
type: SpeciesReference
stoichiometry: 1.0
species: 302487

305742
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value: 0.0

305741
type: LocalParameter
value: 0.0

305740
type: LocalParameter
value: 999999.0

305739
type: LocalParameter
value: -999999.0

720980
type: SpeciesReference
stoichiometry: 1.0
species: 302964

721004
type: SpeciesReference
stoichiometry: 1.0
species: 302958

303081
type: Reaction
reactant: 694972
name: N-acetylglutamate synthase
reversible: false
product: 695008
notes: Abbreviation: R_ACGS Synonyms: _0 EC Number: 2.3.1.1 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : accoa + glu-L --> acglu + coa + h Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 694960
kinetic law: 695020
fast: false
product: 694996
product: 694984

694972
type: SpeciesReference
stoichiometry: 1.0
species: 302633

695008
type: SpeciesReference
stoichiometry: 1.0
species: 302659

694960
type: SpeciesReference
stoichiometry: 1.0
species: 302479

303828
type: LocalParameter
value: 0.0

303827
type: LocalParameter
value: 0.0

303826
type: LocalParameter
value: 999999.0

303824
type: LocalParameter
value: 0.0

694996
type: SpeciesReference
stoichiometry: 1.0
species: 302538

694984
type: SpeciesReference
stoichiometry: 1.0
species: 302484

303401
type: Reaction
reactant: 705979
product: 706015
reactant: 705991
kinetic law: 706027
reversible: false
name: glutamine-fructose-6-phosphate transaminase
product: 706003
notes: Abbreviation: R_GF6PTA Synonyms: _0 EC Number: 2.6.1.16 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : f6p + gln-L --> gam6p + glu-L Confidence Level: 2 genes: LOCUS:BLBBGE_289#ABBREVIATION:glmS#ECNUMBERS:2.6.1.16# proteins: NAME:Glucosamine fructose-6-phosphate aminotransferase (isomerizing)#ABBREVIATION:GlmS# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_289)
fast: false

705979
type: SpeciesReference
stoichiometry: 1.0
species: 302597

706015
type: SpeciesReference
stoichiometry: 1.0
species: 302633

705991
type: SpeciesReference
stoichiometry: 1.0
species: 302628

304615
type: LocalParameter
value: 0.0

304614
type: LocalParameter
value: 0.0

304613
type: LocalParameter
value: 999999.0

304612
type: LocalParameter
value: 0.0

706003
type: SpeciesReference
stoichiometry: 1.0
species: 302622

303117
type: Reaction
kinetic law: 696420
product: 696408
product: 696396
notes: Abbreviation: R_AGPR Synonyms: _0 EC Number: 1.2.1.38 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : acg5sa + nadp + pi <==> acg5p + h + nadph Confidence Level: 2 genes: LOCUS:BLBBGE_314#ABBREVIATION:argC#ECNUMBERS:1.2.1.38# proteins: NAME:N-acetylglutamate phosphate reductase#ABBREVIATION:ArgC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_314)
reactant: 696372
fast: false
reactant: 696360
reversible: true
reactant: 696348
name: N-acetyl-g-glutamyl-phosphate reductase
product: 696384

303930
type: LocalParameter
value: 0.0

303929
type: LocalParameter
value: 0.0

303928
type: LocalParameter
value: 999999.0

303926
type: LocalParameter
value: -999999.0

696408
type: SpeciesReference
stoichiometry: 1.0
species: 302724

696396
type: SpeciesReference
stoichiometry: 1.0
species: 302659

696372
type: SpeciesReference
stoichiometry: 1.0
species: 302853

696360
type: SpeciesReference
stoichiometry: 1.0
species: 302723

696348
type: SpeciesReference
stoichiometry: 1.0
species: 302482

302482
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-Acetyl-L-glutamate 5-semialdehyde_C7H10NO4

696384
type: SpeciesReference
stoichiometry: 1.0
species: 302480

303654
type: Reaction
fast: false
notes: Abbreviation: R_PGK Synonyms: _0 EC Number: 2.7.2.3 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : 3pg + atp <==> 13dpg + adp Confidence Level: 2 SMP genes: LOCUS:BLBBGE_294#ABBREVIATION:pgk#ECNUMBERS:2.7.2.3# proteins: NAME:phosphoglycerate kinase#ABBREVIATION:Pgk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_294)
reactant: 714673
product: 714697
reactant: 714661
name: phosphoglycerate kinase
product: 714685
kinetic law: 714709
reversible: true

714673
type: SpeciesReference
stoichiometry: 1.0
species: 302526

714697
type: SpeciesReference
stoichiometry: 1.0
species: 302493

714661
type: SpeciesReference
stoichiometry: 1.0
species: 302446

714685
type: SpeciesReference
stoichiometry: 1.0
species: 302408

305279
type: LocalParameter
value: 0.0

305278
type: LocalParameter
value: 0.0

305277
type: LocalParameter
value: 999999.0

305276
type: LocalParameter
value: -999999.0

303136
type: Reaction
fast: false
product: 697238
reactant: 697214
kinetic law: 697262
reactant: 697226
product: 697250
notes: Abbreviation: R_ANPRT Synonyms: _0 EC Number: 2.4.2.18 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : anth + prpp --> ppi + pran Confidence Level: 2 genes: LOCUS:BLBBGE_423#ABBREVIATION:trpD#ECNUMBERS:4.1.3.27,-!-,2.4.2.18# proteins: NAME:anthranilate synthase II#ABBREVIATION:TrpD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_423)
reversible: false
name: anthranilate phosphoribosyltransferase

697238
type: SpeciesReference
stoichiometry: 1.0
species: 302865

697214
type: SpeciesReference
stoichiometry: 1.0
species: 302512

303990
type: LocalParameter
value: 0.0

303989
type: LocalParameter
value: 0.0

303988
type: LocalParameter
value: 999999.0

303987
type: LocalParameter
value: 0.0

697226
type: SpeciesReference
stoichiometry: 1.0
species: 302880

697250
type: SpeciesReference
stoichiometry: 1.0
species: 302869

302602
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Fe2+_Fe

303272
type: Reaction
kinetic law: 703171
product: 703159
product: 703147
reactant: 703135
notes: Abbreviation: R_ENO Synonyms: _0 EC Number: 4.2.1.11 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : 2pg <==> h2o + pep Confidence Level: 2 SMP genes: LOCUS:BLBBGE_264#ABBREVIATION:eno#ECNUMBERS:4.2.1.11# proteins: NAME:enolase#ABBREVIATION:Eno# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_264)
fast: false
reversible: true
name: enolase

304326
type: LocalParameter
value: 0.0

304325
type: LocalParameter
value: 0.0

304324
type: LocalParameter
value: 999999.0

304323
type: LocalParameter
value: -999999.0

703159
type: SpeciesReference
stoichiometry: 1.0
species: 302760

703147
type: SpeciesReference
stoichiometry: 1.0
species: 302655

703135
type: SpeciesReference
stoichiometry: 1.0
species: 302431

303226
type: Reaction
kinetic law: 701575
product: 701563
product: 701550
reactant: 701538
notes: Abbreviation: R_DHAD2 Synonyms: _0 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 23dhmp --> 3mop + h2o Confidence Level: 2 genes: LOCUS:BLBBGE_557#ABBREVIATION:ilvD#ECNUMBERS:4.2.1.9# proteins: NAME:dihidroxy acid dehydratase#ABBREVIATION:IlvD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_557)
fast: false
reversible: false
name: Dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate)

304218
type: LocalParameter
value: 0.0

304217
type: LocalParameter
value: 0.0

304216
type: LocalParameter
value: 999999.0

304214
type: LocalParameter
value: 0.0

701563
type: SpeciesReference
stoichiometry: 1.0
species: 302655

701550
type: SpeciesReference
stoichiometry: 1.0
species: 302445

302445
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (S)-3-Methyl-2-oxopentanoate_C6H9O3

701538
type: SpeciesReference
stoichiometry: 1.0
species: 302412

302412
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (R)-2,3-Dihydroxy-3-methylpentanoate_C6H11O4

302477
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Acetate_C2H3O2

303479
type: Reaction
kinetic law: 708698
product: 708686
product: 708674
reactant: 708662
notes: Abbreviation: R_IPPMIa Synonyms: _0 EC Number: 4.2.1.33 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 2ippm + h2o <==> 3c2hmp Confidence Level: 2 genes: LOCUS:BLBBGE_069#ABBREVIATION:leuD#ECNUMBERS:4.2.1.33,-!-,4.2.1.35# LOCUS:BLBBGE_068#ABBREVIATION:leuC#ECNUMBERS:4.2.1.33# proteins: NAME:Isopropylmalate isomerase small subunit#ABBREVIATION:LeuC# NAME:Isopropylmalate isomerase large subunit#ABBREVIATION:LeuD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_068 and BLBBGE_069)
fast: false
reversible: true
name: _3-isopropylmalate dehydratase

304787
type: LocalParameter
value: 0.0

304786
type: LocalParameter
value: 0.0

304785
type: LocalParameter
value: 999999.0

304783
type: LocalParameter
value: -999999.0

708686
type: SpeciesReference
stoichiometry: 1.0
species: 302655

708674
type: SpeciesReference
stoichiometry: 1.0
species: 302426

708662
type: SpeciesReference
stoichiometry: 1.0
species: 302435

303722
type: Reaction
kinetic law: 717601
reversible: false
name: riboflavin kinase
product: 717589
notes: Abbreviation: R_RBFK Synonyms: _0 EC Number: 2.7.1.26 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + ribflv --> adp + fmn + h Confidence Level: 2 genes: LOCUS:BLBBGE_072#ABBREVIATION:ribF#ECNUMBERS:2.7.1.26,-!-,2.7.7.2# proteins: NAME:Flavokinase and FAD synthetase#ABBREVIATION:RibF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_072)
fast: false
reactant: 717539
product: 717576
product: 717564
reactant: 717552

305497
type: LocalParameter
value: 0.0

305495
type: LocalParameter
value: 0.0

305494
type: LocalParameter
value: 999999.0

305492
type: LocalParameter
value: 0.0

717589
type: SpeciesReference
stoichiometry: 1.0
species: 302659

717539
type: SpeciesReference
stoichiometry: 1.0
species: 302526

717576
type: SpeciesReference
stoichiometry: 1.0
species: 302606

717564
type: SpeciesReference
stoichiometry: 1.0
species: 302493

717552
type: SpeciesReference
stoichiometry: 1.0
species: 302899

302899
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Riboflavin_C17H20N4O6

303203
type: Reaction
reversible: true
kinetic law: 700775
product: 700763
notes: Abbreviation: R_CYTK1 Synonyms: _0 EC Number: 2.7.4.14 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + cmp <==> adp + cdp Confidence Level: 2 genes: LOCUS:BLBBGE_058#ABBREVIATION:cmk#ECNUMBERS:2.7.4.14# proteins: NAME:cytidine monophosphate kinase#ABBREVIATION:Cmk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_058)
product: 700751
fast: false
reactant: 700739
reactant: 700727
name: cytidylate kinase (CMP)

304160
type: LocalParameter
value: 0.0

304159
type: LocalParameter
value: 0.0

304158
type: LocalParameter
value: 999999.0

304157
type: LocalParameter
value: -999999.0

700763
type: SpeciesReference
stoichiometry: 1.0
species: 302528

700751
type: SpeciesReference
stoichiometry: 1.0
species: 302493

700739
type: SpeciesReference
stoichiometry: 1.0
species: 302534

700727
type: SpeciesReference
stoichiometry: 1.0
species: 302526

303748
type: Reaction
reversible: false
kinetic law: 718990
product: 718978
reactant: 718929
product: 718954
notes: Abbreviation: R_SUCBZL Synonyms: _0 EC Number: 6.2.1.26 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + coa + sucbz --> amp + ppi + sbzcoa Confidence Level: 2 genes: LOCUS:BLBBGE_271#ABBREVIATION:menE#ECNUMBERS:6.2.1.26# proteins: NAME:O-succinylbenzoate-CoA ligase#ABBREVIATION:MenE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_271)
reactant: 718942
product: 718966
name: o-succinylbenzoate-CoA ligase
fast: false
reactant: 718917

305599
type: LocalParameter
value: 0.0

305598
type: LocalParameter
value: 0.0

305597
type: LocalParameter
value: 999999.0

305596
type: LocalParameter
value: 0.0

718978
type: SpeciesReference
stoichiometry: 1.0
species: 302904

302904
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: O-Succinylbenzoyl-CoA_C32H39N7O20P3S

718929
type: SpeciesReference
stoichiometry: 1.0
species: 302538

718954
type: SpeciesReference
stoichiometry: 1.0
species: 302511

718942
type: SpeciesReference
stoichiometry: 1.0
species: 302923

718966
type: SpeciesReference
stoichiometry: 1.0
species: 302865

718917
type: SpeciesReference
stoichiometry: 1.0
species: 302526

303353
type: Reaction
kinetic law: 704667
product: 704654
reactant: 704641
notes: Abbreviation: R_EX_succ_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : succ <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Succinate exchange

304512
type: LocalParameter
value: 0.0

304511
type: LocalParameter
value: 0.0

304510
type: LocalParameter
value: 999999.0

304508
type: LocalParameter
value: 0.0

704654
type: SpeciesReference
stoichiometry: 1.0
species: 303067

704641
type: SpeciesReference
stoichiometry: 1.0
species: 302925

303185
type: Reaction
kinetic law: 699971
product: 699959
reactant: 699947
notes: Abbreviation: R_CO2t Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: co2[e] <==> co2[c] Confidence Level: 1 renamed from CO2TPr to CO2t genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: CO2 transporter via diffusion

304116
type: LocalParameter
value: 0.0

304115
type: LocalParameter
value: 0.0

304114
type: LocalParameter
value: 999999.0

304113
type: LocalParameter
value: -999999.0

699959
type: SpeciesReference
stoichiometry: 1.0
species: 302536

699947
type: SpeciesReference
stoichiometry: 1.0
species: 302537

303797
type: Reaction
reactant: 721634
name: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase
kinetic law: 721719
fast: false
reversible: false
product: 721695
product: 721671
reactant: 721659
reactant: 721647
product: 721707
product: 721683
notes: Abbreviation: R_UGMDDS Synonyms: _0 EC Number: 6.3.2.15 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : alaala + atp + ugmd --> adp + h + pi + ugmda Confidence Level: 2 genes: LOCUS:BLBBGE_100#ABBREVIATION:murF#ECNUMBERS:6.3.2.10# proteins: NAME:D-alanine:D-alanine-adding enzme#ABBREVIATION:MurF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_100)

721634
type: SpeciesReference
stoichiometry: 1.0
species: 302507

305785
type: LocalParameter
value: 0.0

305784
type: LocalParameter
value: 0.0

305783
type: LocalParameter
value: 999999.0

305782
type: LocalParameter
value: 0.0

721695
type: SpeciesReference
stoichiometry: 1.0
species: 302853

721671
type: SpeciesReference
stoichiometry: 1.0
species: 302493

721659
type: SpeciesReference
stoichiometry: 1.0
species: 302978

721647
type: SpeciesReference
stoichiometry: 1.0
species: 302526

721707
type: SpeciesReference
stoichiometry: 1.0
species: 302979

721683
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303714
type: Reaction
reactant: 717092
fast: false
notes: Abbreviation: R_PUNP5 Synonyms: _0 EC Number: 2.4.2.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : ins + pi <==> hxan + r1p Confidence Level: 2 Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase genes: LOCUS:BLBBGE_377#ABBREVIATION:pndA#ECNUMBERS:2.4.2.1# proteins: NAME:purine-nucleoside phosphorylase#ABBREVIATION:PndA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)
reversible: true
product: 717116
name: purine-nucleoside phosphorylase (Inosine)
product: 717104
kinetic law: 717128
reactant: 717080

717092
type: SpeciesReference
stoichiometry: 1.0
species: 302853

717116
type: SpeciesReference
stoichiometry: 1.0
species: 302895

717104
type: SpeciesReference
stoichiometry: 1.0
species: 302674

305463
type: LocalParameter
value: 0.0

305461
type: LocalParameter
value: 0.0

305460
type: LocalParameter
value: 999999.0

305458
type: LocalParameter
value: -999999.0

717080
type: SpeciesReference
stoichiometry: 1.0
species: 302686

303062
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Pyruvate_C3H3O3

303542
type: Reaction
product: 710960
notes: Abbreviation: R_NADK Synonyms: _0 EC Number: 2.7.1.23 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + nad --> adp + h + nadp Confidence Level: 2 genes: LOCUS:BLBBGE_086#ABBREVIATION:ppnK#ECNUMBERS:2.7.1.23# proteins: NAME:NAD kinase#ABBREVIATION:ppnK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_086)
kinetic law: 710984
product: 710948
reversible: false
fast: false
product: 710972
reactant: 710923
reactant: 710936
name: NAD kinase

710960
type: SpeciesReference
stoichiometry: 1.0
species: 302659

304925
type: LocalParameter
value: 0.0

304924
type: LocalParameter
value: 0.0

304923
type: LocalParameter
value: 999999.0

304922
type: LocalParameter
value: 0.0

710948
type: SpeciesReference
stoichiometry: 1.0
species: 302493

710972
type: SpeciesReference
stoichiometry: 1.0
species: 302723

710923
type: SpeciesReference
stoichiometry: 1.0
species: 302526

710936
type: SpeciesReference
stoichiometry: 1.0
species: 302719

303454
type: Reaction
product: 707847
reactant: 707822
notes: Abbreviation: R_HSST Synonyms: _0 EC Number: 2.3.1.46 SUBSYSTEM: Methionine Metabolism Equation: [c] : hom-L + succoa --> coa + suchms Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 707859
reactant: 707834
reversible: false
fast: false
name: homoserine O-succinyltransferase
kinetic law: 707872

707847
type: SpeciesReference
stoichiometry: 1.0
species: 302538

707822
type: SpeciesReference
stoichiometry: 1.0
species: 302672

707859
type: SpeciesReference
stoichiometry: 1.0
species: 302929

707834
type: SpeciesReference
stoichiometry: 1.0
species: 302928

304729
type: LocalParameter
value: 0.0

304728
type: LocalParameter
value: 0.0

304727
type: LocalParameter
value: 999999.0

304726
type: LocalParameter
value: 0.0

303155
type: Reaction
product: 697979
kinetic law: 697991
product: 697967
fast: false
reactant: 697955
notes: Abbreviation: R_ASPK Synonyms: _0 EC Number: 2.7.2.4 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : asp-L + atp --> 4pasp + adp Confidence Level: 2 genes: LOCUS:BLBBGE_501#ABBREVIATION:thrA#ECNUMBERS:2.7.2.4,-!-,1.1.1.3# proteins: NAME:Homoserine dehydrogenase#ABBREVIATION:MetL# NAME:Aspartate kinase I#ABBREVIATION:ThrA# NAME:Aspartokinase III#ABBREVIATION:LysC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_501)
reversible: false
name: aspartate kinase
reactant: 697943

697979
type: SpeciesReference
stoichiometry: 1.0
species: 302493

304036
type: LocalParameter
value: 0.0

304035
type: LocalParameter
value: 0.0

304034
type: LocalParameter
value: 999999.0

304033
type: LocalParameter
value: 0.0

697967
type: SpeciesReference
stoichiometry: 1.0
species: 302455

697955
type: SpeciesReference
stoichiometry: 1.0
species: 302526

697943
type: SpeciesReference
stoichiometry: 1.0
species: 302522

303109
type: Reaction
kinetic law: 696132
product: 696120
product: 696107
reactant: 696095
notes: Abbreviation: R_ADSL1r Synonyms: _0 EC Number: 4.3.2.2 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : dcamp --> amp + fum Confidence Level: 2 JLR- added reversible form of ADSL1 genes: LOCUS:BLBBGE_487#ABBREVIATION:purB#ECNUMBERS:4.3.2.2# proteins: NAME:Adenylosuccinate lyase#ABBREVIATION:PurB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_487)
fast: false
reversible: false
name: adenylsuccinate lyase

303910
type: LocalParameter
value: 0.0

303909
type: LocalParameter
value: 0.0

303908
type: LocalParameter
value: 999999.0

303907
type: LocalParameter
value: 0.0

696120
type: SpeciesReference
stoichiometry: 1.0
species: 302617

696107
type: SpeciesReference
stoichiometry: 1.0
species: 302511

696095
type: SpeciesReference
stoichiometry: 1.0
species: 302554

302460
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _4-(1-D-Ribitylamino)-5-aminouracil_C9H16N4O6

303253
type: Reaction
reactant: 702494
product: 702506
notes: Abbreviation: R_DNTPPA Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : ahdt + h2o --> dhpmp + h + ppi Confidence Level: 2 JLR- Neidhardt pg 667 genes: LOCUS:BLBBGE_190#ABBREVIATION:idi#ECNUMBERS:5.3.3.2# proteins: NAME:isopentenyl diphosphate isomerase#ABBREVIATION:Idi# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_190)
fast: false
product: 702518
name: Dihydroneopterin triphosphate pyrophosphatase
reactant: 702482
kinetic law: 702542
product: 702530
reversible: false

702494
type: SpeciesReference
stoichiometry: 1.0
species: 302655

702506
type: SpeciesReference
stoichiometry: 1.0
species: 302574

702518
type: SpeciesReference
stoichiometry: 1.0
species: 302659

702482
type: SpeciesReference
stoichiometry: 1.0
species: 302497

302497
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate_C9H12N5O13P3

304284
type: LocalParameter
value: 0.0

304283
type: LocalParameter
value: 0.0

304282
type: LocalParameter
value: 999999.0

304281
type: LocalParameter
value: 0.0

702530
type: SpeciesReference
stoichiometry: 1.0
species: 302865

303599
type: Reaction
reactant: 712789
product: 712801
product: 712825
name: Nucleoside triphosphate pyrophosphorylase (gtp)
reversible: false
reactant: 712777
fast: false
product: 712813
notes: Abbreviation: R_NTPP2 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : gtp + h2o --> gmp + h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
kinetic law: 712837

712789
type: SpeciesReference
stoichiometry: 1.0
species: 302655

712801
type: SpeciesReference
stoichiometry: 1.0
species: 302648

712825
type: SpeciesReference
stoichiometry: 1.0
species: 302865

712777
type: SpeciesReference
stoichiometry: 1.0
species: 302651

712813
type: SpeciesReference
stoichiometry: 1.0
species: 302659

305055
type: LocalParameter
value: 0.0

305054
type: LocalParameter
value: 0.0

305053
type: LocalParameter
value: 999999.0

305051
type: LocalParameter
value: 0.0

303345
type: Reaction
kinetic law: 704516
product: 704504
reactant: 704492
notes: Abbreviation: R_EX_pro_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : pro-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Proline exchange

304494
type: LocalParameter
value: 0.0

304493
type: LocalParameter
value: 0.0

304492
type: LocalParameter
value: 999999.0

304490
type: LocalParameter
value: -999999.0

704504
type: SpeciesReference
stoichiometry: 1.0
species: 303061

704492
type: SpeciesReference
stoichiometry: 1.0
species: 302879

302959
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405

303121
type: Reaction
kinetic law: 696675
product: 696662
reactant: 696650
notes: Abbreviation: R_AIRC3 Synonyms: _2 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : 5caiz --> 5aizc Confidence Level: 2 JLR- E.coli uses a two enzymes in the phosphoribosylaminoimidazole carboxylase step to generate 5aizc genes: LOCUS:BLBBGE_485#ABBREVIATION:purE#ECNUMBERS:4.1.1.21# proteins: NAME:phosphoribosylaminoimidazole carboxylase II#ABBREVIATION:PurE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_485)
fast: false
reversible: false
name: phosphoribosylaminoimidazole carboxylase (mutase rxn)

303950
type: LocalParameter
value: 0.0

303949
type: LocalParameter
value: 0.0

303948
type: LocalParameter
value: 999999.0

303946
type: LocalParameter
value: 0.0

696662
type: SpeciesReference
stoichiometry: 1.0
species: 302461

696650
type: SpeciesReference
stoichiometry: 1.0
species: 302465

302465
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-phosphoribosyl-5-carboxyaminoimidazole_C9H11N3O9P

303264
type: Reaction
name: deoxyuridine phosphorylase
product: 702868
reactant: 702855
reactant: 702843
reversible: true
notes: Abbreviation: R_DURIPP Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : duri + pi <==> 2dr1p + ura Confidence Level: 2 JLR genes: LOCUS:BLBBGE_377#ABBREVIATION:deoD#ECNUMBERS:2.4.2.1# proteins: NAME:Purine-nucleoside phosphorylase#ABBREVIATION:DeoD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)
fast: false
kinetic law: 702892
product: 702880

702868
type: SpeciesReference
stoichiometry: 1.0
species: 302425

702855
type: SpeciesReference
stoichiometry: 1.0
species: 302853

702843
type: SpeciesReference
stoichiometry: 1.0
species: 302589

304308
type: LocalParameter
value: 0.0

304307
type: LocalParameter
value: 0.0

304306
type: LocalParameter
value: 999999.0

304305
type: LocalParameter
value: -999999.0

702880
type: SpeciesReference
stoichiometry: 1.0
species: 302984

303147
type: Reaction
kinetic law: 697689
product: 697677
product: 697665
reactant: 697652
notes: Abbreviation: R_ARGSL Synonyms: _0 EC Number: 4.3.2.1 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : argsuc --> arg-L + fum Confidence Level: 2 genes: LOCUS:BLBBGE_364#ABBREVIATION:argH#ECNUMBERS:4.3.2.1# proteins: NAME:argininosuccinate lyase#ABBREVIATION:ArgH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_364)
fast: false
reversible: false
name: argininosuccinate lyase

304018
type: LocalParameter
value: 0.0

304017
type: LocalParameter
value: 0.0

304016
type: LocalParameter
value: 999999.0

304015
type: LocalParameter
value: 0.0

697677
type: SpeciesReference
stoichiometry: 1.0
species: 302617

697665
type: SpeciesReference
stoichiometry: 1.0
species: 302516

697652
type: SpeciesReference
stoichiometry: 1.0
species: 302518

303733
type: Reaction
fast: false
reactant: 718106
reactant: 718130
reversible: true
product: 718154
name: Sulfate adenyltransferase
product: 718142
reactant: 718094
reactant: 718118
kinetic law: 718190
product: 718178
notes: Abbreviation: R_SADT2 Synonyms: _1 SUBSYSTEM: Cysteine Metabolism Equation: [c] : atp + gtp + h2o + so4 <==> aps + gdp + pi + ppi Confidence Level: 2 tv genes: LOCUS:BLBBGE_275#ABBREVIATION:cysN#ECNUMBERS:2.7.7.4# LOCUS:BLBBGE_274#ABBREVIATION:cysD#ECNUMBERS:2.7.7.4# proteins: NAME:ATP-sulfurylase#ABBREVIATION:CysND# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_275 and BLBBGE_274)
product: 718166

718106
type: SpeciesReference
stoichiometry: 1.0
species: 302651

718130
type: SpeciesReference
stoichiometry: 1.0
species: 302918

302918
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Sulfate_O4S

718154
type: SpeciesReference
stoichiometry: 1.0
species: 302626

718142
type: SpeciesReference
stoichiometry: 1.0
species: 302514

302514
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Adenosine 5'-phosphosulfate_C10H12N5O10PS

718094
type: SpeciesReference
stoichiometry: 1.0
species: 302526

718118
type: SpeciesReference
stoichiometry: 1.0
species: 302655

305539
type: LocalParameter
value: 0.0

305538
type: LocalParameter
value: 0.0

305537
type: LocalParameter
value: 999999.0

305536
type: LocalParameter
value: -999999.0

718178
type: SpeciesReference
stoichiometry: 1.0
species: 302865

718166
type: SpeciesReference
stoichiometry: 1.0
species: 302853

303752
type: Reaction
kinetic law: 719158
product: 719134
reactant: 719122
product: 719146
notes: Abbreviation: R_SUCD1i Synonyms: _0 EC Number: 1.3.99.1 SUBSYSTEM: Citric Acid Cycle Equation: [c] : fad + succ <==> fadh2 + fum Confidence Level: 2 JLR - made an irreversible version of the SUCD1 reaction genes: LOCUS:BLBBGE_151#ABBREVIATION:sdhC# LOCUS:BLBBGE_152#ABBREVIATION:sdhA#ECNUMBERS:1.3.99.1# LOCUS:BLBBGE_153#ABBREVIATION:sdhB#ECNUMBERS:1.3.99.1# proteins: NAME:succinate dehydrogenase#ABBREVIATION:Sdh# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_151 and BLBBGE_152 and BLBBGE_153)
reversible: true
name: succinate dehydrogenase
reactant: 719110
fast: false

305614
type: LocalParameter
value: 0.0

305613
type: LocalParameter
value: 0.0

305612
type: LocalParameter
value: 999999.0

305611
type: LocalParameter
value: -999999.0

719134
type: SpeciesReference
stoichiometry: 1.0
species: 302600

719122
type: SpeciesReference
stoichiometry: 1.0
species: 302924

719146
type: SpeciesReference
stoichiometry: 1.0
species: 302617

719110
type: SpeciesReference
stoichiometry: 1.0
species: 302598

302706
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (R)-mevalonate_C6H11O4

303024
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Glutamine_C5H10N2O3

303269
type: Reaction
reactant: 703063
name: Erythrose 4-phosphate dehydrogenase
kinetic law: 703123
product: 703099
reactant: 703050
fast: false
notes: Abbreviation: R_E4PD Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : e4p + h2o + nad <==> 4per + (2) h + nadh Confidence Level: 2 JLR- Reaction from KEGG R01825 genes: LOCUS:BLBBGE_043#ABBREVIATION:gapA#ECNUMBERS:1.2.1.9# proteins: NAME:Erythrose-4-phosphate dehydrogenase#ABBREVIATION:gapA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_043)
reactant: 703075
product: 703111
reversible: true
product: 703087

703063
type: SpeciesReference
stoichiometry: 1.0
species: 302655

304322
type: LocalParameter
value: 0.0

304321
type: LocalParameter
value: 0.0

304320
type: LocalParameter
value: 999999.0

304319
type: LocalParameter
value: -999999.0

703099
type: SpeciesReference
stoichiometry: 2.0
species: 302659

703050
type: SpeciesReference
stoichiometry: 1.0
species: 302593

703075
type: SpeciesReference
stoichiometry: 1.0
species: 302719

703111
type: SpeciesReference
stoichiometry: 1.0
species: 302720

703087
type: SpeciesReference
stoichiometry: 1.0
species: 302456

303692
type: Reaction
kinetic law: 715936
reactant: 715875
name: phosphoribosylaminoimidazole synthase
fast: false
reactant: 715863
product: 715887
product: 715899
notes: Abbreviation: R_PRAIS Synonyms: _0 EC Number: 6.3.3.1 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : atp + fpram --> adp + air + (2) h + pi Confidence Level: 2 genes: LOCUS:BLBBGE_482#ABBREVIATION:purM#ECNUMBERS:6.3.3.1# proteins: NAME:phosphoribosylaminoimidazole synthetase#ABBREVIATION:PurM# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_482)
product: 715911
reversible: false
product: 715923

305373
type: LocalParameter
value: 0.0

305372
type: LocalParameter
value: 0.0

305371
type: LocalParameter
value: 999999.0

305370
type: LocalParameter
value: 0.0

715875
type: SpeciesReference
stoichiometry: 1.0
species: 302610

715863
type: SpeciesReference
stoichiometry: 1.0
species: 302526

715887
type: SpeciesReference
stoichiometry: 1.0
species: 302493

715899
type: SpeciesReference
stoichiometry: 1.0
species: 302499

715911
type: SpeciesReference
stoichiometry: 2.0
species: 302659

715923
type: SpeciesReference
stoichiometry: 1.0
species: 302853

303789
type: Reaction
name: UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
fast: false
reactant: 721161
product: 721197
product: 721209
kinetic law: 721221
product: 721185
reversible: false
notes: Abbreviation: R_UAGPT3 Synonyms: _0 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : uacgam + uagmda --> h + uaagmda + udp Confidence Level: 2 No exact EC number yet: EC 2.4.1.- catalyzed by murG gene in Bacillus subtilis Also found in H. pylori. Ref: Mendz pg 161 (tv) genes: LOCUS:BLBBGE_386#ABBREVIATION:murG#ECNUMBERS:2.4.1.227# proteins: NAME:N-acetylglucosamine transferase#ABBREVIATION:MurG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_386)
reactant: 721173

721161
type: SpeciesReference
stoichiometry: 1.0
species: 302964

721197
type: SpeciesReference
stoichiometry: 1.0
species: 302960

721209
type: SpeciesReference
stoichiometry: 1.0
species: 302975

305757
type: LocalParameter
value: 0.0

305756
type: LocalParameter
value: 0.0

305755
type: LocalParameter
value: 999999.0

305754
type: LocalParameter
value: 0.0

721185
type: SpeciesReference
stoichiometry: 1.0
species: 302659

721173
type: SpeciesReference
stoichiometry: 1.0
species: 302965

303362
type: Reaction
kinetic law: 704853
product: 704840
reactant: 704828
notes: Abbreviation: R_EX_urea_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : urea <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Urea exchange

304534
type: LocalParameter
value: 0.0

304533
type: LocalParameter
value: 0.0

304532
type: LocalParameter
value: 999999.0

304530
type: LocalParameter
value: 0.0

704840
type: SpeciesReference
stoichiometry: 1.0
species: 303076

303076
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Urea_CH4N2O

704828
type: SpeciesReference
stoichiometry: 1.0
species: 302988

303742
type: Reaction
reactant: 718577
product: 718613
reactant: 718565
notes: Abbreviation: R_SHCHCS2 Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : ichor + ssaltpp --> 2shchc + pyr + thmpp Confidence Level: 2 JLR genes: LOCUS:BLBBGE_056#ABBREVIATION:menD#ECNUMBERS:4.1.1.71,-!-,2.2.1.9# proteins: NAME:bifunctional 2-oxoglutarate decarboxylase/2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase#ABBREVIATION:MenD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_056)
fast: false
product: 718601
kinetic law: 718625
product: 718589
reversible: false
name: _2-succinyl-6-hydroxy-2,4-cyclohexadiene 1-carboxylate synthase

718577
type: SpeciesReference
stoichiometry: 1.0
species: 302920

718613
type: SpeciesReference
stoichiometry: 1.0
species: 302939

718565
type: SpeciesReference
stoichiometry: 1.0
species: 302675

718601
type: SpeciesReference
stoichiometry: 1.0
species: 302893

305576
type: LocalParameter
value: 0.0

305574
type: LocalParameter
value: 0.0

305573
type: LocalParameter
value: 999999.0

305571
type: LocalParameter
value: 0.0

718589
type: SpeciesReference
stoichiometry: 1.0
species: 302432

303725
type: Reaction
kinetic law: 717721
product: 717709
product: 717697
reactant: 717685
notes: Abbreviation: R_RBFSb Synonyms: _0 EC Number: 2.5.1.9 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : (2) dmlz --> 4r5au + ribflv Confidence Level: 2 genes: LOCUS:BLBBGE_547#ABBREVIATION:ribE#ECNUMBERS:2.5.1.9# proteins: NAME:riboflavin synthase#ABBREVIATION:RibH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_547)
fast: false
reversible: false
name: riboflavin synthase

305508
type: LocalParameter
value: 0.0

305506
type: LocalParameter
value: 0.0

305505
type: LocalParameter
value: 999999.0

305503
type: LocalParameter
value: 0.0

717709
type: SpeciesReference
stoichiometry: 1.0
species: 302899

717697
type: SpeciesReference
stoichiometry: 1.0
species: 302460

717685
type: SpeciesReference
stoichiometry: 2.0
species: 302577

302577
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _6,7-Dimethyl-8-(1-D-ribityl)lumazine_C13H18N4O6

303089
type: Reaction
reactant: 695335
notes: Abbreviation: R_ACOTA Synonyms: _0 EC Number: 2.6.1.11 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : acorn + akg <==> acg5sa + glu-L Confidence Level: 2 genes: LOCUS:BLBBGE_315#ABBREVIATION:argD#ECNUMBERS:2.6.1.11,-!-,2.6.1.17# LOCUS:BLBBGE_623#ABBREVIATION:argD#ECNUMBERS:2.6.1.11,-!-,2.6.1.17# proteins: NAME:acetylornithine transaminase#ABBREVIATION:ArgD# NAME:acetylornithine transaminase#ABBREVIATION:ArgD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_315) or (BLBBGE_623)
fast: false
product: 695347
reactant: 695323
product: 695359
kinetic law: 695372
reversible: true
name: acetylornithine transaminase

695335
type: SpeciesReference
stoichiometry: 1.0
species: 302500

695347
type: SpeciesReference
stoichiometry: 1.0
species: 302482

695323
type: SpeciesReference
stoichiometry: 1.0
species: 302485

695359
type: SpeciesReference
stoichiometry: 1.0
species: 302633

303854
type: LocalParameter
value: 0.0

303853
type: LocalParameter
value: 0.0

303852
type: LocalParameter
value: 999999.0

303851
type: LocalParameter
value: -999999.0

303041
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Leucine_C6H13NO2

303409
type: Reaction
reactant: 706292
product: 706341
reversible: false
kinetic law: 706365
reactant: 706304
reactant: 706316
notes: Abbreviation: R_GLUPRT Synonyms: _0 EC Number: 2.4.2.14 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : gln-L + h2o + prpp --> glu-L + ppi + pram Confidence Level: 2 genes: LOCUS:BLBBGE_483#ABBREVIATION:purF#ECNUMBERS:2.4.2.14# proteins: NAME:Amidophosphoribosyltransferase#ABBREVIATION:PurF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_483)
fast: false
product: 706328
name: glutamine phosphoribosyldiphosphate amidotransferase
product: 706353

706292
type: SpeciesReference
stoichiometry: 1.0
species: 302628

706341
type: SpeciesReference
stoichiometry: 1.0
species: 302865

304631
type: LocalParameter
value: 0.0

304630
type: LocalParameter
value: 0.0

304629
type: LocalParameter
value: 999999.0

304628
type: LocalParameter
value: 0.0

706304
type: SpeciesReference
stoichiometry: 1.0
species: 302655

706316
type: SpeciesReference
stoichiometry: 1.0
species: 302880

706328
type: SpeciesReference
stoichiometry: 1.0
species: 302633

706353
type: SpeciesReference
stoichiometry: 1.0
species: 302868

303463
type: Reaction
kinetic law: 708176
product: 708164
product: 708152
reactant: 708140
notes: Abbreviation: R_IGPDH Synonyms: _0 EC Number: 4.2.1.19 SUBSYSTEM: Histidine Metabolism Equation: [c] : eig3p --> h2o + imacp Confidence Level: 2 genes: LOCUS:BLBBGE_436#ABBREVIATION:hisB#ECNUMBERS:3.1.3.15,-!-,4.2.1.19# proteins: NAME:Imidazoleglycerol phosphate dehydratase and Histidinol phosphatase#ABBREVIATION:HisB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_436)
fast: false
reversible: false
name: imidazoleglycerol-phosphate dehydratase

304751
type: LocalParameter
value: 0.0

304750
type: LocalParameter
value: 0.0

304749
type: LocalParameter
value: 999999.0

304748
type: LocalParameter
value: 0.0

708164
type: SpeciesReference
stoichiometry: 1.0
species: 302682

302682
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-(Imidazol-4-yl)-2-oxopropyl phosphate_C6H7N2O5P

708152
type: SpeciesReference
stoichiometry: 1.0
species: 302655

708140
type: SpeciesReference
stoichiometry: 1.0
species: 302595

303610
type: Reaction
product: 713189
kinetic law: 713201
reactant: 713153
name: Nucleoside triphosphate pyrophosphorylase (dttp)
reactant: 713140
notes: Abbreviation: R_NTPP7 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dttp + h2o --> dtmp + h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
reversible: false
fast: false
product: 713177
product: 713165

713189
type: SpeciesReference
stoichiometry: 1.0
species: 302865

305169
type: LocalParameter
value: 0.0

305168
type: LocalParameter
value: 0.0

305167
type: LocalParameter
value: 999999.0

305073
type: LocalParameter
value: 0.0

713153
type: SpeciesReference
stoichiometry: 1.0
species: 302655

713140
type: SpeciesReference
stoichiometry: 1.0
species: 302585

713177
type: SpeciesReference
stoichiometry: 1.0
species: 302659

713165
type: SpeciesReference
stoichiometry: 1.0
species: 302584

303354
type: Reaction
kinetic law: 704706
product: 704693
reactant: 704680
notes: Abbreviation: R_EX_thm_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : thm <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Thiamin exchange

304516
type: LocalParameter
value: 0.0

304515
type: LocalParameter
value: 0.0

304514
type: LocalParameter
value: 999999.0

304513
type: LocalParameter
value: -999999.0

704693
type: SpeciesReference
stoichiometry: 1.0
species: 303068

303068
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Thiamin_C12H17N4OS

704680
type: SpeciesReference
stoichiometry: 1.0
species: 302938

303071
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Threonine_C4H9NO3

303562
type: Reaction
reactant: 711638
product: 711650
notes: Abbreviation: R_NDPK7 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dcdp <==> adp + dctp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions. genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)
product: 711663
reversible: true
fast: false
reactant: 711626
kinetic law: 711675
name: nucleoside-diphosphate kinase (ATP:dCDP)

711638
type: SpeciesReference
stoichiometry: 1.0
species: 302555

711650
type: SpeciesReference
stoichiometry: 1.0
species: 302493

711663
type: SpeciesReference
stoichiometry: 1.0
species: 302557

711626
type: SpeciesReference
stoichiometry: 1.0
species: 302526

304969
type: LocalParameter
value: 0.0

304968
type: LocalParameter
value: 0.0

304967
type: LocalParameter
value: 999999.0

304966
type: LocalParameter
value: -999999.0

303129
type: Reaction
kinetic law: 696942
product: 696930
reactant: 696918
notes: Abbreviation: R_ALAR Synonyms: _0 EC Number: 5.1.1.1 SUBSYSTEM: Alanine and Aspartate Metabolism Equation: [c] : ala-L <==> ala-D Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: alanine racemase

303968
type: LocalParameter
value: 0.0

303967
type: LocalParameter
value: 0.0

303966
type: LocalParameter
value: 999999.0

303965
type: LocalParameter
value: -999999.0

696930
type: SpeciesReference
stoichiometry: 1.0
species: 302503

696918
type: SpeciesReference
stoichiometry: 1.0
species: 302504

303273
type: Reaction
kinetic law: 703207
product: 703195
reactant: 703183
notes: Abbreviation: R_EX_ac_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : ac <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Acetate exchange

304330
type: LocalParameter
value: 0.0

304329
type: LocalParameter
value: 0.0

304328
type: LocalParameter
value: 999999.0

304327
type: LocalParameter
value: 0.0

703195
type: SpeciesReference
stoichiometry: 1.0
species: 303003

703183
type: SpeciesReference
stoichiometry: 1.0
species: 302477

303535
type: Reaction
reactant: 710706
name: NADH dehydrogenase (menaquinone-8 & 2 protons)
fast: false
product: 710718
reactant: 710682
kinetic law: 710754
product: 710742
notes: Abbreviation: R_NADH7 Synonyms: _0 EC Number: 1.6.5.3 SUBSYSTEM: Oxidative Phosphorylation Equation: (3) h[c] + mqn8[c] + nadh[c] --> (2) h[e] + mql8[c] + nad[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_193#ABBREVIATION:ndh#ECNUMBERS:1.16.1.-,-!-,1.6.99.3# proteins: NAME:NADH dehydrogenase II#ABBREVIATION:Ndh# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_193)
product: 710730
reversible: false
reactant: 710694

710706
type: SpeciesReference
stoichiometry: 1.0
species: 302720

710718
type: SpeciesReference
stoichiometry: 2.0
species: 302660

710682
type: SpeciesReference
stoichiometry: 3.0
species: 302659

304913
type: LocalParameter
value: 0.0

304912
type: LocalParameter
value: 0.0

304911
type: LocalParameter
value: 999999.0

304909
type: LocalParameter
value: 0.0

710742
type: SpeciesReference
stoichiometry: 1.0
species: 302719

710730
type: SpeciesReference
stoichiometry: 1.0
species: 302709

710694
type: SpeciesReference
stoichiometry: 1.0
species: 302710

303141
type: Reaction
product: 697483
product: 697507
product: 697471
reversible: false
fast: false
product: 697495
reactant: 697433
name: L-arginine transport via ABC system
kinetic law: 697520
reactant: 697446
reactant: 697458
notes: Abbreviation: R_ARGabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: arg-L[e] + atp[c] + h2o[c] --> adp[c] + arg-L[c] + h[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:

697483
type: SpeciesReference
stoichiometry: 1.0
species: 302516

697507
type: SpeciesReference
stoichiometry: 1.0
species: 302853

697471
type: SpeciesReference
stoichiometry: 1.0
species: 302493

697495
type: SpeciesReference
stoichiometry: 1.0
species: 302659

697433
type: SpeciesReference
stoichiometry: 1.0
species: 302517

304004
type: LocalParameter
value: 0.0

304003
type: LocalParameter
value: 0.0

304002
type: LocalParameter
value: 999999.0

304001
type: LocalParameter
value: 0.0

697446
type: SpeciesReference
stoichiometry: 1.0
species: 302526

697458
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303798
type: Reaction
product: 721755
reversible: false
reactant: 721743
reactant: 721731
notes: Abbreviation: R_UHGADA Synonyms: _0 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : h2o + u3aga --> ac + u3hga Confidence Level: 2 tc genes: LOCUS:BLBBGE_037#ABBREVIATION:lpxC#ECNUMBERS:3.5.1.-# proteins: NAME:UDP-3-O-acyl-N-acetylglucosamine deacetylase#ABBREVIATION:LpxC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_037)
fast: false
kinetic law: 721779
name: UDP-3-O-acetylglucosamine deacetylase
product: 721767

721755
type: SpeciesReference
stoichiometry: 1.0
species: 302475

721743
type: SpeciesReference
stoichiometry: 1.0
species: 302958

721731
type: SpeciesReference
stoichiometry: 1.0
species: 302655

305789
type: LocalParameter
value: 0.0

305788
type: LocalParameter
value: 0.0

305787
type: LocalParameter
value: 999999.0

305786
type: LocalParameter
value: 0.0

721767
type: SpeciesReference
stoichiometry: 1.0
species: 302959

303693
type: Reaction
kinetic law: 715984
product: 715972
reactant: 715960
reactant: 715948
notes: Abbreviation: R_PRAMPC Synonyms: _0 EC Number: 3.5.4.19 SUBSYSTEM: Histidine Metabolism Equation: [c] : h2o + prbamp --> prfp Confidence Level: 2 genes: LOCUS:BLBBGE_440#ABBREVIATION:hisI#ECNUMBERS:3.5.4.19,-!-,3.6.1.31# proteins: NAME:Phosphoribosyl-ATP pyrophosphatase and -AMP cyclohydrolase#ABBREVIATION:HisI# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_440)
fast: false
reversible: false
name: phosphoribosyl-AMP cyclohydrolase

305377
type: LocalParameter
value: 0.0

305376
type: LocalParameter
value: 0.0

305375
type: LocalParameter
value: 999999.0

305374
type: LocalParameter
value: 0.0

715972
type: SpeciesReference
stoichiometry: 1.0
species: 302874

715960
type: SpeciesReference
stoichiometry: 1.0
species: 302870

715948
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303753
type: Reaction
fast: false
kinetic law: 719218
reversible: true
reactant: 719170
notes: Abbreviation: R_SUCD4 Synonyms: _0 SUBSYSTEM: Oxidative Phosphorylation Equation: [c] : fadh2 + mqn8 <==> fad + mql8 Confidence Level: 2 JLR genes: LOCUS:BLBBGE_151#ABBREVIATION:sdhC# LOCUS:BLBBGE_152#ABBREVIATION:sdhA#ECNUMBERS:1.3.99.1# LOCUS:BLBBGE_153#ABBREVIATION:sdhB#ECNUMBERS:1.3.99.1# proteins: NAME:succinate dehydrogenase#ABBREVIATION:Sdh# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_151 and BLBBGE_152 and BLBBGE_153)
product: 719194
name: succinate dehydrogenase
product: 719206
reactant: 719182

305620
type: LocalParameter
value: 0.0

305619
type: LocalParameter
value: 0.0

305617
type: LocalParameter
value: 999999.0

305616
type: LocalParameter
value: -999999.0

719170
type: SpeciesReference
stoichiometry: 1.0
species: 302600

719194
type: SpeciesReference
stoichiometry: 1.0
species: 302598

719206
type: SpeciesReference
stoichiometry: 1.0
species: 302709

719182
type: SpeciesReference
stoichiometry: 1.0
species: 302710

303093
type: Reaction
reactant: 695458
notes: Abbreviation: R_ACt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: ac[e] + h[e] <==> ac[c] + h[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
reversible: true
reactant: 695470
fast: false
name: acetate reversible transport via proton symport
product: 695482
product: 695494
kinetic law: 695506

695458
type: SpeciesReference
stoichiometry: 1.0
species: 302477

695470
type: SpeciesReference
stoichiometry: 1.0
species: 302660

695482
type: SpeciesReference
stoichiometry: 1.0
species: 302475

695494
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303864
type: LocalParameter
value: 0.0

303863
type: LocalParameter
value: 0.0

303862
type: LocalParameter
value: 999999.0

303860
type: LocalParameter
value: -999999.0

303156
type: Reaction
product: 698039
notes: Abbreviation: R_ASPt2 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: asp-L[e] + h[e] --> asp-L[c] + h[c] Confidence Level: 2 genes: LOCUS:BLBBGE_358#ABBREVIATION:gltP# proteins: NAME:DAACS, glutamate or aspartate symport#ABBREVIATION:GltP# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_358)
name: L-aspartate transport in via proton symport
kinetic law: 698052
reversible: false
reactant: 698015
fast: false
product: 698027
reactant: 698003

698039
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stoichiometry: 1.0
species: 302659

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value: 0.0

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value: 999999.0

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species: 302660

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species: 302522

698003
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stoichiometry: 1.0
species: 302523

303666
type: Reaction
product: 715033
reactant: 715009
product: 715021
notes: Abbreviation: R_PMEVKx Synonyms: _0 EC Number: 2.7.4.2 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : 5pmev + atp --> 5dpmev + adp Confidence Level: 2 genes: LOCUS:BLBBGE_085#ABBREVIATION:mvaK#ECNUMBERS:2.7.4.2# proteins: NAME:phosphomevalonate kinase#ABBREVIATION:mvaK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_085)
name: phosphomevalonate kinase
kinetic law: 715045
reversible: false
reactant: 714997
fast: false

715033
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stoichiometry: 1.0
species: 302493

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stoichiometry: 1.0
species: 302526

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species: 302466

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species: 302472

303455
type: Reaction
reactant: 707884
fast: false
kinetic law: 707932
product: 707920
product: 707908
notes: Abbreviation: R_HSTPT Synonyms: _0 EC Number: 2.6.1.9 SUBSYSTEM: Histidine Metabolism Equation: [c] : glu-L + imacp <==> akg + hisp Confidence Level: 2 genes: LOCUS:BLBBGE_435#ABBREVIATION:hisC#ECNUMBERS:2.6.1.9# proteins: NAME:Histidinol phosphate aminotransferase#ABBREVIATION:HisC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_435)
name: histidinol-phosphate transaminase
reversible: true
reactant: 707896

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species: 302633

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species: 302668

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species: 302500

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species: 302682

303768
type: Reaction
product: 720078
reactant: 720054
reactant: 720066
fast: false
notes: Abbreviation: R_TMDK1 Synonyms: _0 EC Number: 2.7.1.21 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + thymd --> adp + dtmp + h Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 720102
product: 720090
reversible: false
name: thymidine kinase (ATP:thymidine)
kinetic law: 720114

720078
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stoichiometry: 1.0
species: 302493

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stoichiometry: 1.0
species: 302526

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species: 302945

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species: 302659

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species: 302584

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303707
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reactant: 716765
reactant: 716789
fast: false
notes: Abbreviation: R_PTPATi Synonyms: _0 EC Number: 2.7.7.3 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + h + pan4p --> dpcoa + ppi Confidence Level: 2 JLR- irreversible form of PTPAT genes: LOCUS:BLBBGE_286#ABBREVIATION:coaD#ECNUMBERS:2.7.7.3# proteins: NAME:phosphopantetheine adenyltransferase#ABBREVIATION:CoaD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_286)
kinetic law: 716826
name: pantetheine-phosphate adenylyltransferase
reactant: 716777
reversible: false
product: 716814
product: 716802

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species: 302526

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species: 302753

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species: 302659

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species: 302581

303373
type: Reaction
product: 705105
reactant: 705069
fast: false
name: iron (II) transport via ABC system
reversible: false
kinetic law: 705142
notes: Abbreviation: R_FE2abc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + fe2[e] + h2o[c] --> adp[c] + fe2[c] + h[c] + pi[c] Confidence Level: 2 genes: LOCUS:BLBBGE_127#ABBREVIATION:feoB# proteins: NAME:Iron(II) transport protein#ABBREVIATION:FeoB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_127)
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reactant: 705057
product: 705093
product: 705130
reactant: 705081

705105
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stoichiometry: 1.0
species: 302602

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stoichiometry: 1.0
species: 302604

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Fe2+_Fe

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value: 999999.0

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species: 302659

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stoichiometry: 1.0
species: 302526

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species: 302493

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stoichiometry: 1.0
species: 302853

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species: 302655

303301
type: Reaction
kinetic law: 703714
product: 703701
reactant: 703689
notes: Abbreviation: R_EX_glu_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : glu-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Glutamate exchange

304394
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value: 0.0

304393
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value: 0.0

304392
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value: 999999.0

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stoichiometry: 1.0
species: 303025

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species: 302634

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type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Glutamate_C5H8NO4

303808
type: Reaction
reversible: true
reactant: 722251
reactant: 722239
notes: Abbreviation: R_VALTA Synonyms: _0 EC Number: 2.6.1.42 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : akg + val-L <==> 3mob + glu-L Confidence Level: 2 genes: LOCUS:BLBBGE_455#ABBREVIATION:ilvE#ECNUMBERS:2.6.1.42,-!-,2.6.1.2# proteins: NAME:Branched-chain-amino-acid aminotransferase#ABBREVIATION:IlvE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_455)
product: 722275
product: 722263
fast: false
name: valine transaminase
kinetic law: 722287

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species: 302993

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species: 302500

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species: 302633

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species: 302444

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value: 0.0

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value: 999999.0

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value: -999999.0

303474
type: Reaction
kinetic law: 708541
reactant: 708480
notes: Abbreviation: R_IMPD Synonyms: _0 EC Number: 1.1.1.205 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : h2o + imp + nad --> h + nadh + xmp Confidence Level: 2 genes: LOCUS:BLBBGE_160#ABBREVIATION:guaB#ECNUMBERS:1.1.1.205# proteins: NAME:Inosine-5'-monophosphate dehydrogenase#ABBREVIATION:GuaB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_160)
fast: false
product: 708516
product: 708528
reactant: 708492
reactant: 708468
reversible: false
product: 708504
name: IMP dehydrogenase

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value: 0.0

304771
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value: 999999.0

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value: 0.0

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species: 302683

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stoichiometry: 1.0
species: 302720

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stoichiometry: 1.0
species: 302998

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stoichiometry: 1.0
species: 302719

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type: SpeciesReference
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species: 302655

708504
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303734
type: Reaction
reversible: false
name: succinyl-diaminopimelate desuccinylase
reactant: 718214
notes: Abbreviation: R_SDPDS Synonyms: _0 EC Number: 3.5.1.18 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : h2o + sl26da --> 26dap-LL + succ Confidence Level: 2 genes: LOCUS:BLBBGE_320#ABBREVIATION:dapE#ECNUMBERS:3.5.1.18# proteins: NAME:Succinyl-diaminopimelate desuccinylase#ABBREVIATION:DapE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_320)
fast: false
product: 718238
reactant: 718202
product: 718226
kinetic law: 718250

718214
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stoichiometry: 1.0
species: 302913

718238
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718202
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species: 302655

718226
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species: 302416

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305544
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value: 0.0

305543
type: LocalParameter
value: 999999.0

305541
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value: 0.0

303365
type: Reaction
kinetic law: 704889
product: 704877
reactant: 704865
notes: Abbreviation: R_EX_val_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : val-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Valine exchange

304538
type: LocalParameter
value: 0.0

304537
type: LocalParameter
value: 0.0

304536
type: LocalParameter
value: 999999.0

304535
type: LocalParameter
value: 0.0

704877
type: SpeciesReference
stoichiometry: 1.0
species: 303077

704865
type: SpeciesReference
stoichiometry: 1.0
species: 302994

303527
type: Reaction
reversible: false
product: 710478
fast: false
reactant: 710453
notes: Abbreviation: R_NACODA Synonyms: _0 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : acg5sa + h2o --> ac + glu5sa Confidence Level: 0 JLR genes: LOCUS:BLBBGE_320#ABBREVIATION:argE#ECNUMBERS:3.5.1.16# proteins: NAME:acetylornithine deacetylase#ABBREVIATION:ArgE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_320)
reactant: 710440
product: 710466
kinetic law: 710490
name: N-acetylornithine deacetylase

710478
type: SpeciesReference
stoichiometry: 1.0
species: 302630

302630
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Glutamate 5-semialdehyde_C5H9NO3

710453
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stoichiometry: 1.0
species: 302655

710440
type: SpeciesReference
stoichiometry: 1.0
species: 302482

710466
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species: 302475

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304894
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304893
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value: 999999.0

304891
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303413
type: Reaction
kinetic law: 706461
fast: false
reactant: 706413
reversible: false
notes: Abbreviation: R_GLUt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: glu-L[e] + h[e] --> glu-L[c] + h[c] Confidence Level: 2 NCD genes: LOCUS:BLBBGE_358#ABBREVIATION:gltP# proteins: NAME:DAACS, glutamate or aspartate symport#ABBREVIATION:GltP# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_358)
reactant: 706425
product: 706449
product: 706437
name: L-glutamate transport via proton symport

304641
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value: 0.0

304640
type: LocalParameter
value: 0.0

304639
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value: 999999.0

304637
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value: 0.0

706413
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stoichiometry: 1.0
species: 302634

706425
type: SpeciesReference
stoichiometry: 1.0
species: 302660

706449
type: SpeciesReference
stoichiometry: 1.0
species: 302659

706437
type: SpeciesReference
stoichiometry: 1.0
species: 302633

303602
type: Reaction
product: 712873
product: 712897
product: 712885
reactant: 712849
kinetic law: 712910
reactant: 712861
fast: false
name: Nucleoside triphosphate pyrophosphorylase (dctp)
notes: Abbreviation: R_NTPP3 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dctp + h2o --> dcmp + h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
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712873
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species: 302556

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type: SpeciesReference
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species: 302659

712849
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species: 302557

305059
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value: 0.0

305058
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value: 0.0

305057
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value: 999999.0

305056
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value: 0.0

712861
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303050
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Nicotinate_C6H4NO2

303306
type: Reaction
kinetic law: 703824
product: 703812
reactant: 703800
notes: Abbreviation: R_EX_glyc_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : glyc <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Glycerol exchange

304408
type: LocalParameter
value: 0.0

304407
type: LocalParameter
value: 0.0

304406
type: LocalParameter
value: 999999.0

304404
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value: 0.0

703812
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stoichiometry: 1.0
species: 303030

703800
type: SpeciesReference
stoichiometry: 1.0
species: 302644

303554
type: Reaction
product: 711421
product: 711409
name: nucleoside-diphosphate kinase (ATP:CDP)
reversible: true
fast: false
reactant: 711397
kinetic law: 711433
reactant: 711385
notes: Abbreviation: R_NDPK3 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + cdp <==> adp + ctp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)

711421
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species: 302541

711409
type: SpeciesReference
stoichiometry: 1.0
species: 302493

711397
type: SpeciesReference
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species: 302528

304953
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304952
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304951
type: LocalParameter
value: 999999.0

304949
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value: -999999.0

711385
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species: 302526

303167
type: Reaction
reactant: 699043
product: 699127
name: Fatty acid biosynthesis (n-C14:0)
reactant: 699055
fast: false
product: 699103
reversible: false
reactant: 699031
kinetic law: 699139
product: 699091
product: 699079
reactant: 699067
product: 699115
notes: Abbreviation: R_C140SN Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : actACP + (17) h + (5) malACP + (12) nadph --> (5) ACP + (5) co2 + (6) h2o + myrsACP + (12) nadp Confidence Level: 2 tvNeidhardt genes: LOCUS:BLBBGE_037#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-# LOCUS:BLBBGE_346#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9# LOCUS:BLBBGE_057#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100# LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.179# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabG# NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI# NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_037) and (BLBBGE_079) and (BLBBGE_346) and (BLBBGE_057)

699043
type: SpeciesReference
stoichiometry: 17.0
species: 302659

699127
type: SpeciesReference
stoichiometry: 12.0
species: 302723

699055
type: SpeciesReference
stoichiometry: 5.0
species: 302697

699103
type: SpeciesReference
stoichiometry: 6.0
species: 302655

699031
type: SpeciesReference
stoichiometry: 1.0
species: 302489

304072
type: LocalParameter
value: 0.0

304071
type: LocalParameter
value: 0.0

304070
type: LocalParameter
value: 999999.0

304069
type: LocalParameter
value: 0.0

699091
type: SpeciesReference
stoichiometry: 5.0
species: 302536

699079
type: SpeciesReference
stoichiometry: 5.0
species: 302487

699067
type: SpeciesReference
stoichiometry: 12.0
species: 302724

699115
type: SpeciesReference
stoichiometry: 1.0
species: 302712

303466
type: Reaction
product: 708212
notes: Abbreviation: R_IGPS Synonyms: _0 EC Number: 4.1.1.48 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : 2cpr5p + h --> 3ig3p + co2 + h2o Confidence Level: 2 genes: LOCUS:BLBBGE_424#ABBREVIATION:trpC#ECNUMBERS:5.3.1.24,-!-,4.1.1.48# proteins: NAME:indole-3-glycerol-phosphate synthase#ABBREVIATION:TrpC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_424)
product: 708224
kinetic law: 708249
reactant: 708200
reactant: 708188
reversible: false
name: indole-3-glycerol-phosphate synthase
fast: false
product: 708236

708212
type: SpeciesReference
stoichiometry: 1.0
species: 302442

708224
type: SpeciesReference
stoichiometry: 1.0
species: 302536

304755
type: LocalParameter
value: 0.0

304754
type: LocalParameter
value: 0.0

304753
type: LocalParameter
value: 999999.0

304752
type: LocalParameter
value: 0.0

708200
type: SpeciesReference
stoichiometry: 1.0
species: 302659

708188
type: SpeciesReference
stoichiometry: 1.0
species: 302420

708236
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303772
type: Reaction
product: 720282
reversible: false
product: 720294
reactant: 720258
fast: false
reactant: 720270
notes: Abbreviation: R_TMDS Synonyms: _4 EC Number: 2.1.1.45 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dump + mlthf --> dhf + dtmp Confidence Level: 2 genes: LOCUS:BLBBGE_498#ABBREVIATION:thyA#ECNUMBERS:2.1.1.45# proteins: NAME:thymidylate synthetase#ABBREVIATION:ThyA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_498)
name: thymidylate synthase
kinetic law: 720306

720282
type: SpeciesReference
stoichiometry: 1.0
species: 302567

720294
type: SpeciesReference
stoichiometry: 1.0
species: 302584

720258
type: SpeciesReference
stoichiometry: 1.0
species: 302588

720270
type: SpeciesReference
stoichiometry: 1.0
species: 302708

305692
type: LocalParameter
value: 0.0

305691
type: LocalParameter
value: 0.0

305690
type: LocalParameter
value: 999999.0

305689
type: LocalParameter
value: 0.0

303216
type: Reaction
fast: false
product: 701162
notes: Abbreviation: R_DB4PS Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : ru5p-D --> db4p + for + h Confidence Level: 2 No EC number: ribA in B. subtilis catalyzes two reactions (GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase) genes: LOCUS:BLBBGE_323#ABBREVIATION:ribBA#ECNUMBERS:3.5.4.25,-!-,4.1.99.12# proteins: NAME:_bifunctional 3,4 dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II#ABBREVIATION:RibBA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_323)
kinetic law: 701199
product: 701187
product: 701175
reversible: false
name: _3,4-Dihydroxy-2-butanone-4-phosphate synthase
reactant: 701150

701162
type: SpeciesReference
stoichiometry: 1.0
species: 302552

304192
type: LocalParameter
value: 0.0

304191
type: LocalParameter
value: 0.0

304190
type: LocalParameter
value: 999999.0

304188
type: LocalParameter
value: 0.0

701187
type: SpeciesReference
stoichiometry: 1.0
species: 302659

701175
type: SpeciesReference
stoichiometry: 1.0
species: 302608

701150
type: SpeciesReference
stoichiometry: 1.0
species: 302900

303618
type: Reaction
kinetic law: 713431
product: 713419
reactant: 713407
notes: Abbreviation: R_O2t Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: o2[e] <==> o2[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: o2 transport (diffusion)

305190
type: LocalParameter
value: 0.0

305189
type: LocalParameter
value: 0.0

305188
type: LocalParameter
value: 999999.0

305187
type: LocalParameter
value: -999999.0

713419
type: SpeciesReference
stoichiometry: 1.0
species: 302733

713407
type: SpeciesReference
stoichiometry: 1.0
species: 302734

303382
type: Reaction
product: 705384
notes: Abbreviation: R_FTHFCL Synonyms: _0 EC Number: 6.3.3.2 SUBSYSTEM: Cofactor Metabolism Equation: [c] : 5fthf + atp --> adp + methf + pi Confidence Level: 2 NCD genes: LOCUS:BLBBGE_130#ABBREVIATION:ygfA#ECNUMBERS:6.3.3.2# proteins: NAME:5-formyltetrahydrofolate cyclo-ligase#ABBREVIATION:YgfA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_130)
kinetic law: 705421
product: 705397
reactant: 705372
product: 705409
reversible: false
reactant: 705360
fast: false
name: _5-formethyltetrahydrofolate cyclo-ligase

705384
type: SpeciesReference
stoichiometry: 1.0
species: 302493

304576
type: LocalParameter
value: 0.0

304575
type: LocalParameter
value: 0.0

304574
type: LocalParameter
value: 999999.0

304573
type: LocalParameter
value: 0.0

705397
type: SpeciesReference
stoichiometry: 1.0
species: 302705

705372
type: SpeciesReference
stoichiometry: 1.0
species: 302526

705409
type: SpeciesReference
stoichiometry: 1.0
species: 302853

705360
type: SpeciesReference
stoichiometry: 1.0
species: 302469

303317
type: Reaction
kinetic law: 704006
product: 703994
reactant: 703982
notes: Abbreviation: R_EX_ile_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : ile-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Isoleucine exchange

304430
type: LocalParameter
value: 0.0

304429
type: LocalParameter
value: 0.0

304428
type: LocalParameter
value: 999999.0

304427
type: LocalParameter
value: 0.0

703994
type: SpeciesReference
stoichiometry: 1.0
species: 303037

703982
type: SpeciesReference
stoichiometry: 1.0
species: 302680

303310
type: Reaction
kinetic law: 703898
product: 703885
reactant: 703872
notes: Abbreviation: R_EX_h2o_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : h2o <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: H2O exchange

304416
type: LocalParameter
value: 0.0

304415
type: LocalParameter
value: 0.0

304414
type: LocalParameter
value: 999999.0

304413
type: LocalParameter
value: -999999.0

703885
type: SpeciesReference
stoichiometry: 1.0
species: 303032

703872
type: SpeciesReference
stoichiometry: 1.0
species: 302656

303175
type: Reaction
reactant: 699511
fast: false
product: 699572
reactant: 699536
kinetic law: 699620
product: 699560
name: Fatty acid biosynthesis (n-C18:1)
reactant: 699523
reversible: false
product: 699608
product: 699596
product: 699584
notes: Abbreviation: R_C181SN Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : actACP + (22) h + (7) malACP + (15) nadph --> (7) ACP + (7) co2 + (8) h2o + (15) nadp + octeACP Confidence Level: 2 tv genes: LOCUS:BLBBGE_037#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-# LOCUS:none#ABBREVIATION:fabA#ECNUMBERS:4.2.1.60# LOCUS:BLBBGE_346#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9# LOCUS:BLBBGE_057#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100# LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.41# LOCUS:BLBBGE_111#ABBREVIATION:fabH#ECNUMBERS:2.3.1.41# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase#ABBREVIATION:FabH# NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabG# NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI# NAME:beta-hydroxydecanoyl thioester dehydrase#ABBREVIATION:FabA# NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_037) and (BLBBGE_079) or (BLBBGE_111) and (BLBBGE_057) and (BLBBGE_346)
reactant: 699548

699511
type: SpeciesReference
stoichiometry: 1.0
species: 302489

699572
type: SpeciesReference
stoichiometry: 7.0
species: 302536

699536
type: SpeciesReference
stoichiometry: 7.0
species: 302697

304090
type: LocalParameter
value: 0.0

304089
type: LocalParameter
value: 0.0

304088
type: LocalParameter
value: 999999.0

304086
type: LocalParameter
value: 0.0

699560
type: SpeciesReference
stoichiometry: 7.0
species: 302487

699523
type: SpeciesReference
stoichiometry: 22.0
species: 302659

699608
type: SpeciesReference
stoichiometry: 1.0
species: 302740

699596
type: SpeciesReference
stoichiometry: 15.0
species: 302723

699584
type: SpeciesReference
stoichiometry: 8.0
species: 302655

699548
type: SpeciesReference
stoichiometry: 15.0
species: 302724

302909
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Shikimate 5-phosphate_C7H8O8P

303663
type: Reaction
product: 714973
name: pyrimidine phosphatase
fast: false
kinetic law: 714985
notes: Abbreviation: R_PMDPHT Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 5aprbu + h2o --> 4r5au + pi Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 714961
reactant: 714949
reversible: false
reactant: 714937

714973
type: SpeciesReference
stoichiometry: 1.0
species: 302853

305305
type: LocalParameter
value: 0.0

305304
type: LocalParameter
value: 0.0

305303
type: LocalParameter
value: 999999.0

305302
type: LocalParameter
value: 0.0

714961
type: SpeciesReference
stoichiometry: 1.0
species: 302460

714949
type: SpeciesReference
stoichiometry: 1.0
species: 302655

714937
type: SpeciesReference
stoichiometry: 1.0
species: 302463

303393
type: Reaction
fast: false
product: 705691
kinetic law: 705727
name: L-glutamate 5-semialdehyde dehydratase (spontaneous)
reactant: 705679
product: 705703
reversible: false
product: 705715
notes: Abbreviation: R_G5SADs Synonyms: _0 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : glu5sa --> 1pyr5c + h + h2o Confidence Level: 1 Needed in L-proline biosynthesis genes: none proteins: none citations: none GENE ASSOCIATION:

705691
type: SpeciesReference
stoichiometry: 1.0
species: 302409

304598
type: LocalParameter
value: 0.0

304597
type: LocalParameter
value: 0.0

304596
type: LocalParameter
value: 999999.0

304595
type: LocalParameter
value: 0.0

705679
type: SpeciesReference
stoichiometry: 1.0
species: 302630

705703
type: SpeciesReference
stoichiometry: 1.0
species: 302659

705715
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303704
type: Reaction
notes: Abbreviation: R_PSERT Synonyms: _0 EC Number: 2.6.1.52 SUBSYSTEM: Glycine and Serine Metabolism Equation: [c] : 3php + glu-L <==> akg + pser-L Confidence Level: 2 genes: LOCUS:BLBBGE_428#ABBREVIATION:serC#ECNUMBERS:2.6.1.52# LOCUS:BLBBGE_144#ABBREVIATION:serC#ECNUMBERS:2.6.1.52# proteins: NAME:Phosphoserine aminotransferase#ABBREVIATION:SerC# NAME:Phosphoserine aminotransferase#ABBREVIATION:SerC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_428) or (BLBBGE_144)
reactant: 716573
kinetic law: 716621
reactant: 716585
fast: false
reversible: true
product: 716609
product: 716597
name: phosphoserine transaminase

716573
type: SpeciesReference
stoichiometry: 1.0
species: 302447

305425
type: LocalParameter
value: 0.0

305423
type: LocalParameter
value: 0.0

305422
type: LocalParameter
value: 999999.0

305420
type: LocalParameter
value: -999999.0

716585
type: SpeciesReference
stoichiometry: 1.0
species: 302633

716609
type: SpeciesReference
stoichiometry: 1.0
species: 302884

716597
type: SpeciesReference
stoichiometry: 1.0
species: 302500

303582
type: Reaction
name: _5'-nucleotidase (UMP)
notes: Abbreviation: R_NTD2 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : h2o + ump --> pi + uri Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 712255
fast: false
reactant: 712218
reactant: 712230
kinetic law: 712267
reversible: false
product: 712243

712255
type: SpeciesReference
stoichiometry: 1.0
species: 302989

712218
type: SpeciesReference
stoichiometry: 1.0
species: 302655

712230
type: SpeciesReference
stoichiometry: 1.0
species: 302980

305015
type: LocalParameter
value: 0.0

305014
type: LocalParameter
value: 0.0

305013
type: LocalParameter
value: 999999.0

305012
type: LocalParameter
value: 0.0

712243
type: SpeciesReference
stoichiometry: 1.0
species: 302853

303243
type: Reaction
reactant: 702120
product: 702156
name: diaminohydroxyphosphoribosylaminopryrimidine deaminase (25drapp)
product: 702168
reactant: 702132
notes: Abbreviation: R_DHPPDA2 Synonyms: _0 EC Number: 3.5.4.26 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 25drapp + h + h2o --> 5apru + nh4 Confidence Level: 2 Riboflavin-specific deaminaseAR genes: LOCUS:BLBBGE_143#ABBREVIATION:ribD#ECNUMBERS:3.5.4.26,-!-,1.1.1.193# proteins: NAME:pyrimidine deaminase and pyrimidine reductase#ABBREVIATION:RibD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_143)
kinetic law: 702180
reactant: 702144
reversible: false
fast: false

702120
type: SpeciesReference
stoichiometry: 1.0
species: 302415

702156
type: SpeciesReference
stoichiometry: 1.0
species: 302464

702168
type: SpeciesReference
stoichiometry: 1.0
species: 302725

702132
type: SpeciesReference
stoichiometry: 1.0
species: 302659

304258
type: LocalParameter
value: 0.0

304257
type: LocalParameter
value: 0.0

304256
type: LocalParameter
value: 999999.0

304254
type: LocalParameter
value: 0.0

702144
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303754
type: Reaction
reactant: 719230
reversible: true
product: 719278
reactant: 719254
name: succinyl-CoA synthetase (ADP-forming)
fast: false
product: 719266
notes: Abbreviation: R_SUCOAS Synonyms: _0 EC Number: 6.2.1.5 SUBSYSTEM: Citric Acid Cycle Equation: [c] : atp + coa + succ <==> adp + pi + succoa Confidence Level: 2 genes: LOCUS:BLBBGE_591#ABBREVIATION:sucC#ECNUMBERS:6.2.1.5# LOCUS:BLBBGE_039#ABBREVIATION:sucD#ECNUMBERS:6.2.1.5# proteins: NAME:succinyl-CoA synthetase alpha chain#ABBREVIATION:SucD# NAME:succinyl-CoA synthetase beta chain#ABBREVIATION:SucC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_591 and BLBBGE_039)
kinetic law: 719302
product: 719290
reactant: 719242

719230
type: SpeciesReference
stoichiometry: 1.0
species: 302526

719278
type: SpeciesReference
stoichiometry: 1.0
species: 302853

719254
type: SpeciesReference
stoichiometry: 1.0
species: 302924

719266
type: SpeciesReference
stoichiometry: 1.0
species: 302493

305624
type: LocalParameter
value: 0.0

305623
type: LocalParameter
value: 0.0

305622
type: LocalParameter
value: 999999.0

305621
type: LocalParameter
value: -999999.0

719290
type: SpeciesReference
stoichiometry: 1.0
species: 302928

719242
type: SpeciesReference
stoichiometry: 1.0
species: 302538

303506
type: Reaction
notes: Abbreviation: R_MALt2_2 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: (2) h[e] + mal-L[e] --> (2) h[c] + mal-L[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_358#ABBREVIATION:dctA# proteins: NAME:C4-dicarboxylate transporter#ABBREVIATION:DctA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_358)
reversible: false
name: Malate transport via proton symport (2 H)
kinetic law: 709703
product: 709690
reactant: 709666
reactant: 709653
product: 709678
fast: false

304845
type: LocalParameter
value: 0.0

304844
type: LocalParameter
value: 0.0

304843
type: LocalParameter
value: 999999.0

304842
type: LocalParameter
value: 0.0

709690
type: SpeciesReference
stoichiometry: 1.0
species: 302698

302698
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Malate_C4H4O5

709666
type: SpeciesReference
stoichiometry: 1.0
species: 302700

709653
type: SpeciesReference
stoichiometry: 2.0
species: 302660

709678
type: SpeciesReference
stoichiometry: 2.0
species: 302659

303410
type: Reaction
kinetic law: 706401
product: 706389
reactant: 706377
notes: Abbreviation: R_GLUR Synonyms: _0 EC Number: 5.1.1.3 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : glu-D <==> glu-L Confidence Level: 2 genes: LOCUS:BLBBGE_411#ABBREVIATION:murI#ECNUMBERS:5.1.1.3# proteins: NAME:glutamate racemase#ABBREVIATION:MurI# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_411)
fast: false
reversible: true
name: glutamate racemase

304635
type: LocalParameter
value: 0.0

304634
type: LocalParameter
value: 0.0

304633
type: LocalParameter
value: 999999.0

304632
type: LocalParameter
value: -999999.0

706389
type: SpeciesReference
stoichiometry: 1.0
species: 302633

706377
type: SpeciesReference
stoichiometry: 1.0
species: 302632

303622
type: Reaction
name: Octaprenyl pyrophosphate synthase
reversible: false
fast: false
product: 713539
reactant: 713527
notes: Abbreviation: R_OCTDPS Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : frdp + (5) ipdp --> octdp + (5) ppi Confidence Level: 2 JLR- EC 2.5.1.- genes: LOCUS:BLBBGE_303#ABBREVIATION:ispB#ECNUMBERS:2.5.1.-# proteins: NAME:Octaprenyl-diphosphate synthase#ABBREVIATION:IspB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_303)
reactant: 713515
kinetic law: 713563
product: 713551

713539
type: SpeciesReference
stoichiometry: 1.0
species: 302739

713527
type: SpeciesReference
stoichiometry: 5.0
species: 302687

713515
type: SpeciesReference
stoichiometry: 1.0
species: 302613

305201
type: LocalParameter
value: 0.0

305200
type: LocalParameter
value: 0.0

305199
type: LocalParameter
value: 999999.0

305198
type: LocalParameter
value: 0.0

713551
type: SpeciesReference
stoichiometry: 5.0
species: 302865

302689
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: potassium_K

303374
type: Reaction
reversible: false
reactant: 705154
fast: false
product: 705203
name: FMN adenylyltransferase
reactant: 705179
notes: Abbreviation: R_FMNAT Synonyms: _0 EC Number: 2.7.7.2 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + fmn + h --> fad + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_072#ABBREVIATION:ribF#ECNUMBERS:2.7.1.26,-!-,2.7.7.2# proteins: NAME:Flavokinase and FAD synthetase#ABBREVIATION:RibF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_072)
kinetic law: 705215
product: 705191
reactant: 705166

705154
type: SpeciesReference
stoichiometry: 1.0
species: 302526

705203
type: SpeciesReference
stoichiometry: 1.0
species: 302865

705179
type: SpeciesReference
stoichiometry: 1.0
species: 302659

304560
type: LocalParameter
value: 0.0

304559
type: LocalParameter
value: 0.0

304558
type: LocalParameter
value: 999999.0

304556
type: LocalParameter
value: 0.0

705191
type: SpeciesReference
stoichiometry: 1.0
species: 302598

705166
type: SpeciesReference
stoichiometry: 1.0
species: 302606

303555
type: Reaction
reversible: true
product: 711469
product: 711481
name: nucleoside-diphosphate kinase (ATP:dTDP)
notes: Abbreviation: R_NDPK4 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dtdp <==> adp + dttp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions. genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)
reactant: 711445
reactant: 711457
fast: false
kinetic law: 711493

711469
type: SpeciesReference
stoichiometry: 1.0
species: 302493

711481
type: SpeciesReference
stoichiometry: 1.0
species: 302585

711445
type: SpeciesReference
stoichiometry: 1.0
species: 302526

711457
type: SpeciesReference
stoichiometry: 1.0
species: 302583

304957
type: LocalParameter
value: 0.0

304956
type: LocalParameter
value: 0.0

304955
type: LocalParameter
value: 999999.0

304954
type: LocalParameter
value: -999999.0

303309
type: Reaction
kinetic law: 703860
product: 703848
reactant: 703836
notes: Abbreviation: R_EX_glyclt_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : glyclt <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Glycolate exchange

304412
type: LocalParameter
value: 0.0

304411
type: LocalParameter
value: 0.0

304410
type: LocalParameter
value: 999999.0

304409
type: LocalParameter
value: 0.0

703848
type: SpeciesReference
stoichiometry: 1.0
species: 303031

703836
type: SpeciesReference
stoichiometry: 1.0
species: 302646

302646
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Glycolate_C2H3O3

303574
type: Reaction
kinetic law: 712023
product: 712011
product: 711999
reactant: 711987
notes: Abbreviation: R_NPHS Synonyms: _0 EC Number: 4.1.3.36 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : sbzcoa --> coa + dhna Confidence Level: 2 genes: LOCUS:BLBBGE_267#ABBREVIATION:menB#ECNUMBERS:4.1.3.36# proteins: NAME:Napthoate synthase#ABBREVIATION:MenB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_267)
fast: false
reversible: false
name: naphthoate synthase

304997
type: LocalParameter
value: 0.0

304996
type: LocalParameter
value: 0.0

304995
type: LocalParameter
value: 999999.0

304994
type: LocalParameter
value: 0.0

712011
type: SpeciesReference
stoichiometry: 1.0
species: 302569

711999
type: SpeciesReference
stoichiometry: 1.0
species: 302538

711987
type: SpeciesReference
stoichiometry: 1.0
species: 302904

303220
type: Reaction
reactant: 701296
reversible: false
notes: Abbreviation: R_DCYTD Synonyms: _0 EC Number: 3.5.4.14 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dcyt + h + h2o --> duri + nh4 Confidence Level: 2 genes: LOCUS:BLBBGE_495#ABBREVIATION:cdd#ECNUMBERS:3.5.4.5# proteins: NAME:cytidine/deoxycytidine deaminase#ABBREVIATION:Cdd# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_495)
fast: false
kinetic law: 701344
product: 701320
reactant: 701309
reactant: 701284
product: 701332
name: deoxycytidine deaminase

701296
type: SpeciesReference
stoichiometry: 1.0
species: 302659

304200
type: LocalParameter
value: 0.0

304199
type: LocalParameter
value: 0.0

304198
type: LocalParameter
value: 999999.0

304197
type: LocalParameter
value: 0.0

701320
type: SpeciesReference
stoichiometry: 1.0
species: 302589

701309
type: SpeciesReference
stoichiometry: 1.0
species: 302655

701284
type: SpeciesReference
stoichiometry: 1.0
species: 302559

701332
type: SpeciesReference
stoichiometry: 1.0
species: 302725

303235
type: Reaction
reactant: 701890
product: 701915
product: 701927
product: 701939
fast: false
reactant: 701902
kinetic law: 701963
product: 701951
reversible: false
notes: Abbreviation: R_DHNAOT Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : dhna + octdp --> 2dmmq8 + co2 + h + ppi Confidence Level: 2 EC 2.5.1-;Reaction is uncharged the loss of 2H (conversion from quinol to quinone form is thought to be spontaneous) genes: LOCUS:BLBBGE_268#ABBREVIATION:menA#ECNUMBERS:2.5.1.-# proteins: NAME:_1,4 dihydroxy-2-napthoate octaprenyltransferase#ABBREVIATION:MenA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_268)
name: _1,4-dihydroxy-2-naphthoate octaprenyltransferase

701890
type: SpeciesReference
stoichiometry: 1.0
species: 302569

701915
type: SpeciesReference
stoichiometry: 1.0
species: 302422

701927
type: SpeciesReference
stoichiometry: 1.0
species: 302536

701939
type: SpeciesReference
stoichiometry: 1.0
species: 302659

701902
type: SpeciesReference
stoichiometry: 1.0
species: 302739

304240
type: LocalParameter
value: 0.0

304239
type: LocalParameter
value: 0.0

304238
type: LocalParameter
value: 999999.0

304236
type: LocalParameter
value: 0.0

701951
type: SpeciesReference
stoichiometry: 1.0
species: 302865

303194
type: Reaction
kinetic law: 700415
name: cysteine synthase
product: 700391
reactant: 700355
reactant: 700367
fast: false
product: 700403
product: 700379
reversible: false
notes: Abbreviation: R_CYSS Synonyms: _8 SUBSYSTEM: Cysteine Metabolism Equation: [c] : acser + h2s --> ac + cys-L + h Confidence Level: 2 EC changed to 2.5.1.47 from 4.2.99.8 genes: LOCUS:BLBBGE_277#ABBREVIATION:cysK#ECNUMBERS:2.5.1.47# proteins: NAME:Cysteine synthase A#ABBREVIATION:CysK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_277)

304138
type: LocalParameter
value: 0.0

304137
type: LocalParameter
value: 0.0

304136
type: LocalParameter
value: 999999.0

304135
type: LocalParameter
value: 0.0

700391
type: SpeciesReference
stoichiometry: 1.0
species: 302542

700355
type: SpeciesReference
stoichiometry: 1.0
species: 302488

700367
type: SpeciesReference
stoichiometry: 1.0
species: 302658

700403
type: SpeciesReference
stoichiometry: 1.0
species: 302659

700379
type: SpeciesReference
stoichiometry: 1.0
species: 302475

303225
type: Reaction
kinetic law: 701526
product: 701514
product: 701502
reactant: 701489
notes: Abbreviation: R_DHAD1 Synonyms: _0 EC Number: 4.2.1.9 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 23dhmb --> 3mob + h2o Confidence Level: 2 genes: LOCUS:BLBBGE_557#ABBREVIATION:ilvD#ECNUMBERS:4.2.1.9# proteins: NAME:dihidroxy acid dehydratase#ABBREVIATION:IlvD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_557)
fast: false
reversible: false
name: dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate)

304212
type: LocalParameter
value: 0.0

304211
type: LocalParameter
value: 0.0

304210
type: LocalParameter
value: 999999.0

304209
type: LocalParameter
value: 0.0

701514
type: SpeciesReference
stoichiometry: 1.0
species: 302655

701502
type: SpeciesReference
stoichiometry: 1.0
species: 302444

701489
type: SpeciesReference
stoichiometry: 1.0
species: 302411

303103
type: Reaction
product: 695867
name: adentylate kinase (GTP)
product: 695855
reactant: 695831
fast: false
kinetic law: 695879
reactant: 695843
reversible: true
notes: Abbreviation: R_ADK3 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : amp + gtp <==> adp + gdp Confidence Level: 2 JLR genes: LOCUS:BLBBGE_215#ABBREVIATION:adk#ECNUMBERS:2.7.4.3# proteins: NAME:Adenylate kinase#ABBREVIATION:Adk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_215)

695867
type: SpeciesReference
stoichiometry: 1.0
species: 302626

695855
type: SpeciesReference
stoichiometry: 1.0
species: 302493

695831
type: SpeciesReference
stoichiometry: 1.0
species: 302511

303890
type: LocalParameter
value: 0.0

303889
type: LocalParameter
value: 0.0

303888
type: LocalParameter
value: 999999.0

303887
type: LocalParameter
value: -999999.0

695843
type: SpeciesReference
stoichiometry: 1.0
species: 302651

303321
type: Reaction
kinetic law: 704078
product: 704066
reactant: 704054
notes: Abbreviation: R_EX_leu_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : leu-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Leucine exchange

304438
type: LocalParameter
value: 0.0

304437
type: LocalParameter
value: 0.0

304436
type: LocalParameter
value: 999999.0

304435
type: LocalParameter
value: 0.0

704066
type: SpeciesReference
stoichiometry: 1.0
species: 303041

704054
type: SpeciesReference
stoichiometry: 1.0
species: 302693

302470
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Methyltetrahydrofolate_C20H24N7O6

303184
type: Reaction
product: 699923
kinetic law: 699935
product: 699911
reversible: false
reactant: 699887
name: CMP nucleosidase
notes: Abbreviation: R_CMPN Synonyms: _0 EC Number: 3.2.2.10 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : cmp + h2o --> csn + r5p Confidence Level: 1 JLR - also acts on dUMP, dCMP,dTMP, and presumably TMP and UMP genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reactant: 699899

699923
type: SpeciesReference
stoichiometry: 1.0
species: 302898

304112
type: LocalParameter
value: 0.0

304111
type: LocalParameter
value: 0.0

304110
type: LocalParameter
value: 999999.0

304108
type: LocalParameter
value: 0.0

699911
type: SpeciesReference
stoichiometry: 1.0
species: 302539

699887
type: SpeciesReference
stoichiometry: 1.0
species: 302534

699899
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303510
type: Reaction
reactant: 709788
product: 709800
product: 709812
name: malate dehydrogenase
reactant: 709776
notes: Abbreviation: R_MDH Synonyms: _0 EC Number: 1.1.1.37 SUBSYSTEM: Citric Acid Cycle Equation: [c] : mal-L + nad <==> h + nadh + oaa Confidence Level: 2 genes: LOCUS:BLBBGE_617#ABBREVIATION:mdh#ECNUMBERS:1.1.1.37# proteins: NAME:malate dehydrogenase#ABBREVIATION:Mdh# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_617)
product: 709825
reversible: true
kinetic law: 709837
fast: false

709788
type: SpeciesReference
stoichiometry: 1.0
species: 302719

709800
type: SpeciesReference
stoichiometry: 1.0
species: 302659

709812
type: SpeciesReference
stoichiometry: 1.0
species: 302720

709776
type: SpeciesReference
stoichiometry: 1.0
species: 302698

709825
type: SpeciesReference
stoichiometry: 1.0
species: 302738

304853
type: LocalParameter
value: 0.0

304852
type: LocalParameter
value: 0.0

304851
type: LocalParameter
value: 999999.0

304850
type: LocalParameter
value: -999999.0

303385
type: Reaction
kinetic law: 705469
product: 705457
reactant: 705445
reactant: 705433
notes: Abbreviation: R_FUM Synonyms: _0 EC Number: 4.2.1.2 SUBSYSTEM: Citric Acid Cycle Equation: [c] : fum + h2o <==> mal-L Confidence Level: 2 genes: LOCUS:BLBBGE_536#ABBREVIATION:fumC#ECNUMBERS:4.2.1.2# proteins: NAME:fumarase C#ABBREVIATION:FumC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_536)
fast: false
reversible: true
name: fumarase

304580
type: LocalParameter
value: 0.0

304579
type: LocalParameter
value: 0.0

304578
type: LocalParameter
value: 999999.0

304577
type: LocalParameter
value: -999999.0

705457
type: SpeciesReference
stoichiometry: 1.0
species: 302698

705445
type: SpeciesReference
stoichiometry: 1.0
species: 302655

705433
type: SpeciesReference
stoichiometry: 1.0
species: 302617

303547
type: Reaction
notes: Abbreviation: R_NAt3_1 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h[e] + na1[c] <==> h[c] + na1[e] Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 711201
product: 711225
product: 711237
fast: false
reversible: true
reactant: 711213
kinetic law: 711250
name: sodium proton antiporter (H:NA is 1:1)

711201
type: SpeciesReference
stoichiometry: 1.0
species: 302660

711225
type: SpeciesReference
stoichiometry: 1.0
species: 302659

711237
type: SpeciesReference
stoichiometry: 1.0
species: 302714

711213
type: SpeciesReference
stoichiometry: 1.0
species: 302713

304939
type: LocalParameter
value: 0.0

304938
type: LocalParameter
value: 0.0

304937
type: LocalParameter
value: 999999.0

304936
type: LocalParameter
value: -999999.0

303108
type: Reaction
fast: false
name: adenylyl-sulfate kinase
notes: Abbreviation: R_ADSK Synonyms: _0 EC Number: 2.7.1.25 SUBSYSTEM: Cysteine Metabolism Equation: [c] : aps + atp --> adp + h + paps Confidence Level: 2 genes: LOCUS:BLBBGE_275#ABBREVIATION:cysC#ECNUMBERS:2.7.1.25# proteins: NAME:adenosine 5'-phosphosulfate kinase#ABBREVIATION:CysC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_275)
product: 696047
reversible: false
product: 696071
product: 696059
kinetic law: 696083
reactant: 696035
reactant: 696023

696047
type: SpeciesReference
stoichiometry: 1.0
species: 302493

696071
type: SpeciesReference
stoichiometry: 1.0
species: 302755

696059
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303906
type: LocalParameter
value: 0.0

303905
type: LocalParameter
value: 0.0

303904
type: LocalParameter
value: 999999.0

303902
type: LocalParameter
value: 0.0

696035
type: SpeciesReference
stoichiometry: 1.0
species: 302526

696023
type: SpeciesReference
stoichiometry: 1.0
species: 302514

303278
type: Reaction
kinetic law: 703315
product: 703303
reactant: 703291
notes: Abbreviation: R_EX_arg_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : arg-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Arginine exchange

304344
type: LocalParameter
value: 0.0

304343
type: LocalParameter
value: 0.0

304342
type: LocalParameter
value: 999999.0

304341
type: LocalParameter
value: 0.0

703303
type: SpeciesReference
stoichiometry: 1.0
species: 303008

703291
type: SpeciesReference
stoichiometry: 1.0
species: 302517

303326
type: Reaction
kinetic law: 704188
product: 704176
reactant: 704163
notes: Abbreviation: R_EX_met_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : met-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Methionine exchange

304452
type: LocalParameter
value: 0.0

304451
type: LocalParameter
value: 0.0

304450
type: LocalParameter
value: 999999.0

304449
type: LocalParameter
value: 0.0

704176
type: SpeciesReference
stoichiometry: 1.0
species: 303046

704163
type: SpeciesReference
stoichiometry: 1.0
species: 302704

303146
type: Reaction
notes: Abbreviation: R_ARGN Synonyms: _0 EC Number: 3.5.3.1 SUBSYSTEM: Urea cycle/amino group metabolism Equation: [c] : arg-L + h2o --> orn + urea Confidence Level: 2 genes: LOCUS:BLBBGE_059#ABBREVIATION:rocF,speB#ECNUMBERS:3.5.3.1# proteins: NAME:agmatinase#ABBREVIATION:rocF,speB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_059)
name: arginase
reactant: 697592
reactant: 697604
fast: false
product: 697628
kinetic law: 697640
product: 697616
reversible: false

697592
type: SpeciesReference
stoichiometry: 1.0
species: 302516

697604
type: SpeciesReference
stoichiometry: 1.0
species: 302655

697628
type: SpeciesReference
stoichiometry: 1.0
species: 302985

304014
type: LocalParameter
value: 0.0

304013
type: LocalParameter
value: 0.0

304012
type: LocalParameter
value: 999999.0

304010
type: LocalParameter
value: 0.0

697616
type: SpeciesReference
stoichiometry: 1.0
species: 302744

303120
type: Reaction
reversible: false
reactant: 696553
fast: false
product: 696613
product: 696601
reactant: 696577
notes: Abbreviation: R_AIRC2 Synonyms: _0 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : air + atp + hco3 --> 5caiz + adp + h + pi Confidence Level: 1 JLR- reaction according to Neidhardt pg 563 and 569. According to Meyer et al. Biochemistry 38: 3012-3018pp, this pathway is used in prokaryotes and uses hco3 instead of co2 genes: none proteins: none citations: none GENE ASSOCIATION:
kinetic law: 696637
product: 696625
product: 696589
reactant: 696565
name: phosphoribosylaminoimidazole carboxylase

696553
type: SpeciesReference
stoichiometry: 1.0
species: 302499

696613
type: SpeciesReference
stoichiometry: 1.0
species: 302659

696601
type: SpeciesReference
stoichiometry: 1.0
species: 302493

696577
type: SpeciesReference
stoichiometry: 1.0
species: 302662

303944
type: LocalParameter
value: 0.0

303943
type: LocalParameter
value: 0.0

303942
type: LocalParameter
value: 999999.0

303941
type: LocalParameter
value: 0.0

696625
type: SpeciesReference
stoichiometry: 1.0
species: 302853

696589
type: SpeciesReference
stoichiometry: 1.0
species: 302465

696565
type: SpeciesReference
stoichiometry: 1.0
species: 302526

303217
type: Reaction
reactant: 701236
reactant: 701212
fast: false
notes: Abbreviation: R_DCMPDA Synonyms: _1 EC Number: 3.5.4.12 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dcmp + h + h2o <==> dump + nh4 Confidence Level: 2 genes: LOCUS:BLBBGE_505#ABBREVIATION:comEB#ECNUMBERS:3.5.4.12# proteins: NAME:dCMP deaminase#ABBREVIATION:ComEB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_505)
reactant: 701224
product: 701248
name: _dCMP deaminase
product: 701260
kinetic law: 701272
reversible: true

701236
type: SpeciesReference
stoichiometry: 1.0
species: 302655

701212
type: SpeciesReference
stoichiometry: 1.0
species: 302556

701224
type: SpeciesReference
stoichiometry: 1.0
species: 302659

701248
type: SpeciesReference
stoichiometry: 1.0
species: 302588

701260
type: SpeciesReference
stoichiometry: 1.0
species: 302725

304196
type: LocalParameter
value: 0.0

304195
type: LocalParameter
value: 0.0

304194
type: LocalParameter
value: 999999.0

304193
type: LocalParameter
value: -999999.0

303751
type: Reaction
product: 719086
name: succinate transport via proton symport (2 H)
notes: Abbreviation: R_SUCCt2_2 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: (2) h[e] + succ[e] --> (2) h[c] + succ[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_358#ABBREVIATION:dctA# proteins: NAME:C4-dicarboxylate transporter#ABBREVIATION:DctA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_358)
reactant: 719050
kinetic law: 719098
product: 719074
fast: false
reactant: 719062
reversible: false

719086
type: SpeciesReference
stoichiometry: 1.0
species: 302924

719050
type: SpeciesReference
stoichiometry: 2.0
species: 302660

305610
type: LocalParameter
value: 0.0

305609
type: LocalParameter
value: 0.0

305608
type: LocalParameter
value: 999999.0

305607
type: LocalParameter
value: 0.0

719074
type: SpeciesReference
stoichiometry: 2.0
species: 302659

719062
type: SpeciesReference
stoichiometry: 1.0
species: 302925

303318
type: Reaction
kinetic law: 704042
product: 704030
reactant: 704018
notes: Abbreviation: R_EX_k_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : k <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: K+ exchange

304434
type: LocalParameter
value: 0.0

304433
type: LocalParameter
value: 0.0

304432
type: LocalParameter
value: 999999.0

304431
type: LocalParameter
value: -999999.0

704030
type: SpeciesReference
stoichiometry: 1.0
species: 303040

704018
type: SpeciesReference
stoichiometry: 1.0
species: 302691

303131
type: Reaction
reactant: 697016
kinetic law: 697066
notes: Abbreviation: R_ALATA_L Synonyms: _0 EC Number: 2.6.1.2 SUBSYSTEM: Glutamate metabolism Equation: [c] : akg + ala-L <==> glu-L + pyr Confidence Level: 2 genes: LOCUS:BLBBGE_455#ABBREVIATION:ilvE#ECNUMBERS:2.6.1.42,-!-,2.6.1.2# proteins: NAME:Branched-chain-amino-acid aminotransferase#ABBREVIATION:IlvE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_455)
product: 697053
name: L-alanine transaminase
reactant: 697028
fast: false
reversible: true
product: 697041

697016
type: SpeciesReference
stoichiometry: 1.0
species: 302500

303976
type: LocalParameter
value: 0.0

303975
type: LocalParameter
value: 0.0

303974
type: LocalParameter
value: 999999.0

303973
type: LocalParameter
value: -999999.0

697053
type: SpeciesReference
stoichiometry: 1.0
species: 302893

697028
type: SpeciesReference
stoichiometry: 1.0
species: 302504

697041
type: SpeciesReference
stoichiometry: 1.0
species: 302633

303176
type: Reaction
kinetic law: 699669
product: 699657
product: 699645
reactant: 699632
notes: Abbreviation: R_CAT Synonyms: _4 EC Number: 1.11.1.6 SUBSYSTEM: Unassigned Equation: [c] : (2) h2o2 --> (2) h2o + o2 Confidence Level: 2 JLR genes: LOCUS:BLBBGE_349#ABBREVIATION:ahpC#ECNUMBERS:1.11.1.6# proteins: NAME:peroxiredoxin#ABBREVIATION:ahpC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_349)
fast: false
reversible: false
name: catalase

304094
type: LocalParameter
value: 0.0

304093
type: LocalParameter
value: 0.0

304092
type: LocalParameter
value: 999999.0

304091
type: LocalParameter
value: 0.0

699657
type: SpeciesReference
stoichiometry: 1.0
species: 302733

699645
type: SpeciesReference
stoichiometry: 2.0
species: 302655

699632
type: SpeciesReference
stoichiometry: 2.0
species: 302654

303430
type: Reaction
kinetic law: 707039
notes: Abbreviation: R_GTPCI Synonyms: _0 EC Number: 3.5.4.16 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : gtp + h2o --> ahdt + for Confidence Level: 2 The reaction involves hydrolysis of two C-N bonds and isomerization of the pentose unit; the recyclization may be non-enzymic genes: LOCUS:BLBBGE_570#ABBREVIATION:folE#ECNUMBERS:3.5.4.16# proteins: NAME:GTP cyclohydrolase I#ABBREVIATION:FolE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_570)
product: 707015
reversible: false
fast: false
reactant: 707003
product: 707027
reactant: 706991
name: GTP cyclohydrolase I

304679
type: LocalParameter
value: 0.0

304678
type: LocalParameter
value: 0.0

304677
type: LocalParameter
value: 999999.0

304676
type: LocalParameter
value: 0.0

707015
type: SpeciesReference
stoichiometry: 1.0
species: 302497

707003
type: SpeciesReference
stoichiometry: 1.0
species: 302655

707027
type: SpeciesReference
stoichiometry: 1.0
species: 302608

706991
type: SpeciesReference
stoichiometry: 1.0
species: 302651

303290
type: Reaction
kinetic law: 703533
product: 703521
reactant: 703509
notes: Abbreviation: R_EX_fe2_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : fe2 <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Fe2+ exchange

304372
type: LocalParameter
value: 0.0

304371
type: LocalParameter
value: 0.0

304370
type: LocalParameter
value: 999999.0

304368
type: LocalParameter
value: -999999.0

703521
type: SpeciesReference
stoichiometry: 1.0
species: 303018

303018
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Fe2+_Fe

703509
type: SpeciesReference
stoichiometry: 1.0
species: 302604

303788
type: Reaction
kinetic law: 721149
reversible: false
product: 721125
product: 721137
name: UDP-N-acetylglucosamine diphosphorylase
reactant: 721101
reactant: 721113
fast: false
reactant: 721089
notes: Abbreviation: R_UAGDP Synonyms: _0 EC Number: 2.7.7.23 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : acgam1p + h + utp --> ppi + uacgam Confidence Level: 2 genes: LOCUS:BLBBGE_605#ABBREVIATION:galU#ECNUMBERS:2.7.7.23# proteins: NAME:UTP-glucose-1-phosphate uridylyltransferase#ABBREVIATION:galU# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_605)

305753
type: LocalParameter
value: 0.0

305752
type: LocalParameter
value: 0.0

305751
type: LocalParameter
value: 999999.0

305750
type: LocalParameter
value: 0.0

721125
type: SpeciesReference
stoichiometry: 1.0
species: 302865

721137
type: SpeciesReference
stoichiometry: 1.0
species: 302964

721101
type: SpeciesReference
stoichiometry: 1.0
species: 302659

721113
type: SpeciesReference
stoichiometry: 1.0
species: 302990

721089
type: SpeciesReference
stoichiometry: 1.0
species: 302483

303394
type: Reaction
product: 705775
reactant: 705763
product: 705799
reactant: 705751
name: glyceraldehyde-3-phosphate dehydrogenase
fast: false
reactant: 705739
product: 705787
kinetic law: 705811
notes: Abbreviation: R_GAPD Synonyms: _0 EC Number: 1.2.1.12 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : g3p + nad + pi <==> 13dpg + h + nadh Confidence Level: 2 SMP genes: LOCUS:BLBBGE_043#ABBREVIATION:gapA#ECNUMBERS:1.2.1.12# proteins: NAME:glyceraldehyde-3-phosphate dehydrogenase A#ABBREVIATION:GapA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_043)
reversible: true

705775
type: SpeciesReference
stoichiometry: 1.0
species: 302408

705763
type: SpeciesReference
stoichiometry: 1.0
species: 302853

705799
type: SpeciesReference
stoichiometry: 1.0
species: 302720

705751
type: SpeciesReference
stoichiometry: 1.0
species: 302719

705739
type: SpeciesReference
stoichiometry: 1.0
species: 302620

705787
type: SpeciesReference
stoichiometry: 1.0
species: 302659

304602
type: LocalParameter
value: 0.0

304601
type: LocalParameter
value: 0.0

304600
type: LocalParameter
value: 999999.0

304599
type: LocalParameter
value: -999999.0

303119
type: Reaction
notes: Abbreviation: R_AICART Synonyms: _0 EC Number: 2.1.2.3 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : 10fthf + aicar --> fprica + thf Confidence Level: 2 genes: LOCUS:BLBBGE_480#ABBREVIATION:purH#ECNUMBERS:3.5.4.10,-!-,2.1.2.3# proteins: NAME:AICAR transformylase and IMP cyclohydrolase#ABBREVIATION:PurH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_480)
product: 696517
reactant: 696505
fast: false
kinetic law: 696541
name: phosphoribosylaminoimidazolecarboxamide formyltransferase
reactant: 696492
reversible: false
product: 696529

696517
type: SpeciesReference
stoichiometry: 1.0
species: 302612

696505
type: SpeciesReference
stoichiometry: 1.0
species: 302498

303940
type: LocalParameter
value: 0.0

303939
type: LocalParameter
value: 0.0

303938
type: LocalParameter
value: 999999.0

303936
type: LocalParameter
value: 0.0

696492
type: SpeciesReference
stoichiometry: 1.0
species: 302407

696529
type: SpeciesReference
stoichiometry: 1.0
species: 302934

303112
type: Reaction
kinetic law: 696180
product: 696168
product: 696156
reactant: 696144
notes: Abbreviation: R_ADSL2r Synonyms: _0 EC Number: 4.3.2.2 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : 25aics --> aicar + fum Confidence Level: 2 JLR- added reversible form of ADSL2 genes: LOCUS:BLBBGE_487#ABBREVIATION:purB#ECNUMBERS:4.3.2.2# proteins: NAME:Adenylosuccinate lyase#ABBREVIATION:PurB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_487)
fast: false
reversible: false
name: adenylosuccinate lyase

303916
type: LocalParameter
value: 0.0

303915
type: LocalParameter
value: 0.0

303914
type: LocalParameter
value: 999999.0

303912
type: LocalParameter
value: 0.0

696168
type: SpeciesReference
stoichiometry: 1.0
species: 302617

696156
type: SpeciesReference
stoichiometry: 1.0
species: 302498

696144
type: SpeciesReference
stoichiometry: 1.0
species: 302413

303337
type: Reaction
kinetic law: 704369
product: 704357
reactant: 704345
notes: Abbreviation: R_EX_phe_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : phe-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Phenylalanine exchange

304474
type: LocalParameter
value: 0.0

304473
type: LocalParameter
value: 0.0

304472
type: LocalParameter
value: 999999.0

304471
type: LocalParameter
value: 0.0

704357
type: SpeciesReference
stoichiometry: 1.0
species: 303055

704345
type: SpeciesReference
stoichiometry: 1.0
species: 302765

303330
type: Reaction
kinetic law: 704261
product: 704249
reactant: 704237
notes: Abbreviation: R_EX_nac_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : nac <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Nicotinate exchange

304462
type: LocalParameter
value: 0.0

304461
type: LocalParameter
value: 0.0

304460
type: LocalParameter
value: 999999.0

304458
type: LocalParameter
value: -999999.0

704249
type: SpeciesReference
stoichiometry: 1.0
species: 303050

704237
type: SpeciesReference
stoichiometry: 1.0
species: 302718

303195
type: Reaction
reversible: false
name: cystathionine b-lyase
kinetic law: 700487
product: 700463
product: 700451
reactant: 700427
notes: Abbreviation: R_CYSTL Synonyms: _0 EC Number: 4.4.1.8 SUBSYSTEM: Methionine Metabolism Equation: [c] : cyst-L + h2o --> hcys-L + nh4 + pyr Confidence Level: 2 genes: LOCUS:BLBBGE_568#ABBREVIATION:metBC#ECNUMBERS:4.4.1.8# proteins: NAME:Cystathionine gamma-synthase-cystathionine beta-lyase#ABBREVIATION:MetC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_568)
fast: false
product: 700475
reactant: 700439

304142
type: LocalParameter
value: 0.0

304141
type: LocalParameter
value: 0.0

304140
type: LocalParameter
value: 999999.0

304139
type: LocalParameter
value: 0.0

700463
type: SpeciesReference
stoichiometry: 1.0
species: 302725

700451
type: SpeciesReference
stoichiometry: 1.0
species: 302663

700427
type: SpeciesReference
stoichiometry: 1.0
species: 302544

700475
type: SpeciesReference
stoichiometry: 1.0
species: 302893

700439
type: SpeciesReference
stoichiometry: 1.0
species: 302655

302914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-Succinyl-2-L-amino-6-oxoheptanedioate_C11H12NO8

303418
type: Reaction
reactant: 706605
fast: false
name: glycolate transport via proton symport, reversible
product: 706642
reactant: 706618
notes: Abbreviation: R_GLYCLTt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: glyclt[e] + h[e] <==> glyclt[c] + h[c] Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
reversible: true
kinetic law: 706654
product: 706630

706605
type: SpeciesReference
stoichiometry: 1.0
species: 302646

706642
type: SpeciesReference
stoichiometry: 1.0
species: 302659

706618
type: SpeciesReference
stoichiometry: 1.0
species: 302660

304653
type: LocalParameter
value: 0.0

304652
type: LocalParameter
value: 0.0

304651
type: LocalParameter
value: 999999.0

304650
type: LocalParameter
value: -999999.0

706630
type: SpeciesReference
stoichiometry: 1.0
species: 302645

303683
type: Reaction
reversible: false
reactant: 715600
kinetic law: 715649
notes: Abbreviation: R_PPNDH Synonyms: _0 EC Number: 4.2.1.51 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : h + pphn --> co2 + h2o + phpyr Confidence Level: 2 genes: LOCUS:BLBBGE_341#ABBREVIATION:pheA#ECNUMBERS:5.4.99.5,-!-,4.2.1.51# proteins: NAME:Chorismate mutase P#ABBREVIATION:PheA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_341)
product: 715612
reactant: 715588
name: prephenate dehydratase
fast: false
product: 715637
product: 715624

715600
type: SpeciesReference
stoichiometry: 1.0
species: 302864

305354
type: LocalParameter
value: 0.0

305353
type: LocalParameter
value: 0.0

305352
type: LocalParameter
value: 999999.0

305351
type: LocalParameter
value: 0.0

715612
type: SpeciesReference
stoichiometry: 1.0
species: 302536

715588
type: SpeciesReference
stoichiometry: 1.0
species: 302659

715637
type: SpeciesReference
stoichiometry: 1.0
species: 302769

715624
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303724
type: Reaction
notes: Abbreviation: R_RBFSa Synonyms: _0 EC Number: 2.5.1.9 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 4r5au + db4p --> dmlz + (2) h2o + pi Confidence Level: 2 genes: LOCUS:BLBBGE_076#ABBREVIATION:ribC#ECNUMBERS:2.5.1.9# proteins: NAME:_6,7-dimethyl-8-ribityllumazine synthase#ABBREVIATION:RibC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_076)
product: 717649
product: 717661
name: riboflavin synthase
kinetic law: 717673
product: 717637
reactant: 717613
reversible: false
fast: false
reactant: 717625

717649
type: SpeciesReference
stoichiometry: 2.0
species: 302655

717661
type: SpeciesReference
stoichiometry: 1.0
species: 302853

305501
type: LocalParameter
value: 0.0

305500
type: LocalParameter
value: 0.0

305499
type: LocalParameter
value: 999999.0

305498
type: LocalParameter
value: 0.0

717637
type: SpeciesReference
stoichiometry: 1.0
species: 302577

717613
type: SpeciesReference
stoichiometry: 1.0
species: 302460

717625
type: SpeciesReference
stoichiometry: 1.0
species: 302552

303511
type: Reaction
kinetic law: 709911
reactant: 709849
fast: false
notes: Abbreviation: R_ME2 Synonyms: _6 EC Number: 1.1.1.40 SUBSYSTEM: Anaplerotic reactions Equation: [c] : mal-L + nadp --> co2 + nadph + pyr Confidence Level: 2 genes: LOCUS:BLBBGE_412#ABBREVIATION:maeB# proteins: NAME:Malic enzyme (NADP)#ABBREVIATION:Mae# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_412)
product: 709899
product: 709886
name: malic enzyme (NADP)
reactant: 709862
reversible: false
product: 709874

304859
type: LocalParameter
value: 0.0

304858
type: LocalParameter
value: 0.0

304857
type: LocalParameter
value: 999999.0

304855
type: LocalParameter
value: 0.0

709849
type: SpeciesReference
stoichiometry: 1.0
species: 302698

709899
type: SpeciesReference
stoichiometry: 1.0
species: 302893

709886
type: SpeciesReference
stoichiometry: 1.0
species: 302724

709862
type: SpeciesReference
stoichiometry: 1.0
species: 302723

709874
type: SpeciesReference
stoichiometry: 1.0
species: 302536

303282
type: Reaction
kinetic law: 703387
product: 703375
reactant: 703363
notes: Abbreviation: R_EX_asp_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : asp-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Aspartate exchange

304354
type: LocalParameter
value: 0.0

304353
type: LocalParameter
value: 0.0

304352
type: LocalParameter
value: 999999.0

304350
type: LocalParameter
value: 0.0

703375
type: SpeciesReference
stoichiometry: 1.0
species: 303010

703363
type: SpeciesReference
stoichiometry: 1.0
species: 302523

303792
type: Reaction
fast: false
reactant: 721343
kinetic law: 721416
name: UDP-N-acetylmuramoyl-L-alanine synthetase
reactant: 721355
product: 721368
product: 721404
reversible: false
reactant: 721331
notes: Abbreviation: R_UAMAS Synonyms: _0 EC Number: 6.3.2.8 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : ala-L + atp + uamr --> adp + h + pi + uama Confidence Level: 2 genes: LOCUS:BLBBGE_385#ABBREVIATION:murC#ECNUMBERS:6.3.2.8# proteins: NAME:UDP-N-acetylmuramate-alanine ligase#ABBREVIATION:MurC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_385)
product: 721380
product: 721392

721343
type: SpeciesReference
stoichiometry: 1.0
species: 302526

305765
type: LocalParameter
value: 0.0

305764
type: LocalParameter
value: 0.0

305763
type: LocalParameter
value: 999999.0

305762
type: LocalParameter
value: 0.0

721355
type: SpeciesReference
stoichiometry: 1.0
species: 302970

721368
type: SpeciesReference
stoichiometry: 1.0
species: 302493

721404
type: SpeciesReference
stoichiometry: 1.0
species: 302968

721331
type: SpeciesReference
stoichiometry: 1.0
species: 302504

721380
type: SpeciesReference
stoichiometry: 1.0
species: 302659

721392
type: SpeciesReference
stoichiometry: 1.0
species: 302853

303716
type: Reaction
fast: false
product: 717236
kinetic law: 717249
reversible: true
name: purine-nucleoside phosphorylase (Xanthosine)
product: 717224
reactant: 717200
notes: Abbreviation: R_PUNP7 Synonyms: _0 EC Number: 2.4.2.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : pi + xtsn <==> r1p + xan Confidence Level: 2 Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferasextsn genes: LOCUS:BLBBGE_377#ABBREVIATION:pndA#ECNUMBERS:2.4.2.1# proteins: NAME:purine-nucleoside phosphorylase#ABBREVIATION:PndA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)
reactant: 717212

717236
type: SpeciesReference
stoichiometry: 1.0
species: 302995

305471
type: LocalParameter
value: 0.0

305470
type: LocalParameter
value: 0.0

305469
type: LocalParameter
value: 999999.0

305468
type: LocalParameter
value: -999999.0

717224
type: SpeciesReference
stoichiometry: 1.0
species: 302895

717200
type: SpeciesReference
stoichiometry: 1.0
species: 302853

717212
type: SpeciesReference
stoichiometry: 1.0
species: 302999

303567
type: Reaction
kinetic law: 711831
product: 711819
reactant: 711807
notes: Abbreviation: R_NH4t Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: nh4[e] <==> nh4[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: ammonia reversible transport

304983
type: LocalParameter
value: 0.0

304982
type: LocalParameter
value: 0.0

304981
type: LocalParameter
value: 999999.0

304980
type: LocalParameter
value: -999999.0

711819
type: SpeciesReference
stoichiometry: 1.0
species: 302725

711807
type: SpeciesReference
stoichiometry: 1.0
species: 302728

303701
type: Reaction
reversible: false
fast: false
name: _3-phosphoshikimate 1-carboxyvinyltransferase
product: 716477
reactant: 716453
notes: Abbreviation: R_PSCVT Synonyms: _0 EC Number: 2.5.1.19 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : pep + skm5p --> 3psme + pi Confidence Level: 2 genes: LOCUS:BLBBGE_406#ABBREVIATION:aroA#ECNUMBERS:2.5.1.19# proteins: NAME:_3-phosphoshikimate 1-carboxyvinyltransferase#ABBREVIATION:AroA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_406)
reactant: 716465
product: 716489
kinetic law: 716501

716477
type: SpeciesReference
stoichiometry: 1.0
species: 302449

716453
type: SpeciesReference
stoichiometry: 1.0
species: 302760

716465
type: SpeciesReference
stoichiometry: 1.0
species: 302909

716489
type: SpeciesReference
stoichiometry: 1.0
species: 302853

305414
type: LocalParameter
value: 0.0

305412
type: LocalParameter
value: 0.0

305411
type: LocalParameter
value: 999999.0

305409
type: LocalParameter
value: 0.0

303329
type: Reaction
kinetic law: 704225
product: 704213
reactant: 704200
notes: Abbreviation: R_EX_na1_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : na1 <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Sodium exchange

304456
type: LocalParameter
value: 0.0

304455
type: LocalParameter
value: 0.0

304454
type: LocalParameter
value: 999999.0

304453
type: LocalParameter
value: -999999.0

704213
type: SpeciesReference
stoichiometry: 1.0
species: 303047

303047
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Sodium_Na

704200
type: SpeciesReference
stoichiometry: 1.0
species: 302714

303802
type: Reaction
kinetic law: 721961
product: 721937
reactant: 721901
fast: false
notes: Abbreviation: R_UREA Synonyms: _0 EC Number: 3.5.1.5 Equation: [c] : (2) h + h2o + urea --> co2 + (2) nh4 Confidence Level: 4 genes: LOCUS:BLBBGE_502#ABBREVIATION:ureAB#ECNUMBERS:3.5.1.5# LOCUS:BLBBGE_503#ABBREVIATION:ureC#ECNUMBERS:3.5.1.5# proteins: NAME:Urease, alpha subunit#ABBREVIATION:UreC# NAME:Urease beta gamma subunit#ABBREVIATION:UreAB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_502) and (BLBBGE_503)
reactant: 721913
name: urease
product: 721949
reversible: false
reactant: 721925

305805
type: LocalParameter
value: 0.0

305804
type: LocalParameter
value: 0.0

305803
type: LocalParameter
value: 999999.0

305802
type: LocalParameter
value: 0.0

721937
type: SpeciesReference
stoichiometry: 1.0
species: 302536

721901
type: SpeciesReference
stoichiometry: 2.0
species: 302659

721913
type: SpeciesReference
stoichiometry: 1.0
species: 302655

721949
type: SpeciesReference
stoichiometry: 2.0
species: 302725

721925
type: SpeciesReference
stoichiometry: 1.0
species: 302985

303518
type: Reaction
reversible: true
kinetic law: 710152
notes: Abbreviation: R_METS Synonyms: _0 EC Number: 2.1.1.14 SUBSYSTEM: Methionine Metabolism Equation: [c] : 5mthf + hcys-L <==> met-L + thf Confidence Level: 2 genes: LOCUS:BLBBGE_114#ABBREVIATION:metE#ECNUMBERS:2.1.1.14# proteins: NAME:Cobalamin independent methionine synthase#ABBREVIATION:MetE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_114)
reactant: 710116
reactant: 710104
product: 710140
name: methionine synthase
product: 710128
fast: false

304871
type: LocalParameter
value: 0.0

304870
type: LocalParameter
value: 0.0

304869
type: LocalParameter
value: 999999.0

304868
type: LocalParameter
value: -999999.0

710116
type: SpeciesReference
stoichiometry: 1.0
species: 302663

710104
type: SpeciesReference
stoichiometry: 1.0
species: 302470

710140
type: SpeciesReference
stoichiometry: 1.0
species: 302934

710128
type: SpeciesReference
stoichiometry: 1.0
species: 302702

303140
type: Reaction
kinetic law: 697421
reversible: false
fast: false
notes: Abbreviation: R_APRAUR Synonyms: _0 EC Number: 1.1.1.193 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 5apru + h + nadph --> 5aprbu + nadp Confidence Level: 2 genes: LOCUS:BLBBGE_143#ABBREVIATION:ribD#ECNUMBERS:3.5.4.26,-!-,1.1.1.193# proteins: NAME:pyrimidine deaminase and pyrimidine reductase#ABBREVIATION:RibD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_143)
name: _5-amino-6-(5-phosphoribosylamino)uracil reductase
reactant: 697360
product: 697396
reactant: 697372
reactant: 697384
product: 697408

304000
type: LocalParameter
value: 0.0

303999
type: LocalParameter
value: 0.0

303998
type: LocalParameter
value: 999999.0

303996
type: LocalParameter
value: 0.0

697360
type: SpeciesReference
stoichiometry: 1.0
species: 302464

697396
type: SpeciesReference
stoichiometry: 1.0
species: 302463

697372
type: SpeciesReference
stoichiometry: 1.0
species: 302659

697384
type: SpeciesReference
stoichiometry: 1.0
species: 302724

697408
type: SpeciesReference
stoichiometry: 1.0
species: 302723

303422
type: Reaction
product: 706751
product: 706739
reversible: false
fast: false
product: 706727
notes: Abbreviation: R_GLYK Synonyms: _0 EC Number: 2.7.1.30 SUBSYSTEM: Alternate Carbon Metabolism Equation: [c] : atp + glyc --> adp + glyc3p + h Confidence Level: 2 genes: LOCUS:BLBBGE_459#ABBREVIATION:glpK#ECNUMBERS:2.7.1.30# proteins: NAME:glycerol kinase#ABBREVIATION:GlpK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_459)
reactant: 706715
name: glycerol kinase
kinetic law: 706763
reactant: 706703

706751
type: SpeciesReference
stoichiometry: 1.0
species: 302659

706739
type: SpeciesReference
stoichiometry: 1.0
species: 302641

706727
type: SpeciesReference
stoichiometry: 1.0
species: 302493

706715
type: SpeciesReference
stoichiometry: 1.0
species: 302642

304661
type: LocalParameter
value: 0.0

304660
type: LocalParameter
value: 0.0

304659
type: LocalParameter
value: 999999.0

304658
type: LocalParameter
value: 0.0

706703
type: SpeciesReference
stoichiometry: 1.0
species: 302526

303675
type: Reaction
product: 715321
notes: Abbreviation: R_PPCK Synonyms: _0 EC Number: 4.1.1.49 SUBSYSTEM: Anaplerotic reactions Equation: [c] : atp + oaa --> adp + co2 + pep Confidence Level: 2 genes: LOCUS:BLBBGE_077#ABBREVIATION:pck#ECNUMBERS:4.1.1.49# proteins: NAME:phosphoenolpyruvate carboxykinase#ABBREVIATION:Pck# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_077)
reactant: 715285
product: 715333
fast: false
product: 715309
reversible: false
reactant: 715297
kinetic law: 715345
name: phosphoenolpyruvate carboxykinase

715321
type: SpeciesReference
stoichiometry: 1.0
species: 302536

715285
type: SpeciesReference
stoichiometry: 1.0
species: 302526

715333
type: SpeciesReference
stoichiometry: 1.0
species: 302760

715309
type: SpeciesReference
stoichiometry: 1.0
species: 302493

715297
type: SpeciesReference
stoichiometry: 1.0
species: 302738

305338
type: LocalParameter
value: 0.0

305337
type: LocalParameter
value: 0.0

305335
type: LocalParameter
value: 999999.0

305334
type: LocalParameter
value: 0.0

303092
type: Reaction
product: 695421
product: 695409
reactant: 695397
fast: false
product: 695433
kinetic law: 695445
notes: Abbreviation: R_ACPS1 Synonyms: _0 EC Number: 2.7.8.7 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : apoACP + coa --> ACP + h + pap Confidence Level: 4 JLR genes: LOCUS:BLBBGE_379#ABBREVIATION:acpT#ECNUMBERS:2.7.8.7# proteins: NAME:holo-(acyl carrier protein) synthase 2#ABBREVIATION:AcpT# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_379)
reversible: false
reactant: 695384
name: acyl-carrier protein synthase

695421
type: SpeciesReference
stoichiometry: 1.0
species: 302659

695409
type: SpeciesReference
stoichiometry: 1.0
species: 302487

695397
type: SpeciesReference
stoichiometry: 1.0
species: 302538

695433
type: SpeciesReference
stoichiometry: 1.0
species: 302754

303858
type: LocalParameter
value: 0.0

303857
type: LocalParameter
value: 0.0

303856
type: LocalParameter
value: 999999.0

303855
type: LocalParameter
value: 0.0

695384
type: SpeciesReference
stoichiometry: 1.0
species: 302513

303341
type: Reaction
kinetic law: 704443
product: 704430
reactant: 704417
notes: Abbreviation: R_EX_pnto_R_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : pnto-R <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: (R)-Pantothenate exchange

304484
type: LocalParameter
value: 0.0

304483
type: LocalParameter
value: 0.0

304482
type: LocalParameter
value: 999999.0

304481
type: LocalParameter
value: -999999.0

704430
type: SpeciesReference
stoichiometry: 1.0
species: 303057

704417
type: SpeciesReference
stoichiometry: 1.0
species: 302859

303594
type: Reaction
kinetic law: 712632
name: _5'-nucleotidase (dGMP)
reactant: 712596
product: 712620
product: 712608
reactant: 712584
notes: Abbreviation: R_NTD8 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dgmp + h2o --> dgsn + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
reversible: false
fast: false

305041
type: LocalParameter
value: 0.0

305040
type: LocalParameter
value: 0.0

305039
type: LocalParameter
value: 999999.0

305038
type: LocalParameter
value: 0.0

712596
type: SpeciesReference
stoichiometry: 1.0
species: 302655

712620
type: SpeciesReference
stoichiometry: 1.0
species: 302853

712608
type: SpeciesReference
stoichiometry: 1.0
species: 302564

712584
type: SpeciesReference
stoichiometry: 1.0
species: 302562

303503
type: Reaction
notes: Abbreviation: R_LYSabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + lys-L[e] --> adp[c] + h[c] + lys-L[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 709581
kinetic law: 709641
reversible: false
product: 709605
name: L-lysine transport via ABC system
product: 709629
reactant: 709557
reactant: 709569
fast: false
product: 709593
product: 709617

709581
type: SpeciesReference
stoichiometry: 1.0
species: 302696

304841
type: LocalParameter
value: 0.0

304840
type: LocalParameter
value: 0.0

304839
type: LocalParameter
value: 999999.0

304837
type: LocalParameter
value: 0.0

709605
type: SpeciesReference
stoichiometry: 1.0
species: 302659

709629
type: SpeciesReference
stoichiometry: 1.0
species: 302853

709557
type: SpeciesReference
stoichiometry: 1.0
species: 302526

709569
type: SpeciesReference
stoichiometry: 1.0
species: 302655

709593
type: SpeciesReference
stoichiometry: 1.0
species: 302493

709617
type: SpeciesReference
stoichiometry: 1.0
species: 302694

303706
type: Reaction
kinetic law: 716753
product: 716717
name: Phosphatidylserine syntase
reactant: 716693
reversible: false
reactant: 716705
product: 716741
notes: Abbreviation: R_PSSA_Bge Synonyms: _0 EC Number: 2.7.8.8 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : (0.02) cdpdag_Bge + ser-L --> cmp + h + (0.02) ps_Bge Confidence Level: 2 tv genes: LOCUS:BLBBGE_532#ABBREVIATION:pssA#ECNUMBERS:2.7.8.8# proteins: NAME:Phosphatidylserine synthase#ABBREVIATION:PssA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_532)
fast: false
product: 716729

305433
type: LocalParameter
value: 0.0

305432
type: LocalParameter
value: 0.0

305431
type: LocalParameter
value: 999999.0

305430
type: LocalParameter
value: 0.0

716717
type: SpeciesReference
stoichiometry: 1.0
species: 302534

716693
type: SpeciesReference
stoichiometry: 0.02
species: 302529

716705
type: SpeciesReference
stoichiometry: 1.0
species: 302905

716741
type: SpeciesReference
stoichiometry: 0.02
species: 302883

716729
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303807
type: Reaction
product: 722179
product: 722215
reactant: 722155
reactant: 722143
product: 722191
notes: Abbreviation: R_VALabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + val-L[e] --> adp[c] + h[c] + pi[c] + val-L[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
kinetic law: 722227
reversible: false
name: L-valine transport via ABC system
reactant: 722167
product: 722203

722179
type: SpeciesReference
stoichiometry: 1.0
species: 302493

722215
type: SpeciesReference
stoichiometry: 1.0
species: 302993

722155
type: SpeciesReference
stoichiometry: 1.0
species: 302655

722143
type: SpeciesReference
stoichiometry: 1.0
species: 302526

722191
type: SpeciesReference
stoichiometry: 1.0
species: 302659

305825
type: LocalParameter
value: 0.0

305823
type: LocalParameter
value: 0.0

305821
type: LocalParameter
value: 999999.0

305819
type: LocalParameter
value: 0.0

722167
type: SpeciesReference
stoichiometry: 1.0
species: 302994

722203
type: SpeciesReference
stoichiometry: 1.0
species: 302853

302944
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Thymine_C5H6N2O2

303139
type: Reaction
reactant: 697274
product: 697322
fast: false
name: anthranilate synthase
reversible: false
product: 697310
product: 697335
reactant: 697286
product: 697298
kinetic law: 697347
notes: Abbreviation: R_ANS Synonyms: _0 EC Number: 4.1.3.27 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : chor + gln-L --> anth + glu-L + h + pyr Confidence Level: 2 genes: LOCUS:BLBBGE_422#ABBREVIATION:trpD#ECNUMBERS:4.1.3.27,-!-,2.4.2.18# LOCUS:BLBBGE_421#ABBREVIATION:trpE#ECNUMBERS:4.1.3.27# proteins: NAME:Anthranilate synthase I#ABBREVIATION:TrpE# NAME:anthranilate synthase II#ABBREVIATION:TrpD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_421) and (BLBBGE_422)

697274
type: SpeciesReference
stoichiometry: 1.0
species: 302531

697322
type: SpeciesReference
stoichiometry: 1.0
species: 302659

697310
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stoichiometry: 1.0
species: 302633

697335
type: SpeciesReference
stoichiometry: 1.0
species: 302893

697286
type: SpeciesReference
stoichiometry: 1.0
species: 302628

697298
type: SpeciesReference
stoichiometry: 1.0
species: 302512

303994
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value: 0.0

303993
type: LocalParameter
value: 0.0

303992
type: LocalParameter
value: 999999.0

303991
type: LocalParameter
value: 0.0

303759
type: Reaction
reactant: 719557
reactant: 719581
reversible: true
kinetic law: 719617
fast: false
product: 719593
product: 719605
reactant: 719569
name: tetrahydrodipicolinate succinylase
notes: Abbreviation: R_THDPS Synonyms: _0 EC Number: 2.3.1.117 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : h2o + succoa + thdp <==> coa + sl2a6o Confidence Level: 2 genes: LOCUS:BLBBGE_467#ABBREVIATION:dapD#ECNUMBERS:2.3.1.117# proteins: NAME:Tetrahydrodipicolinate N-succinultransferase#ABBREVIATION:DapD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_467)

719557
type: SpeciesReference
stoichiometry: 1.0
species: 302655

719581
type: SpeciesReference
stoichiometry: 1.0
species: 302933

305643
type: LocalParameter
value: 0.0

305641
type: LocalParameter
value: 0.0

305640
type: LocalParameter
value: 999999.0

305638
type: LocalParameter
value: -999999.0

719593
type: SpeciesReference
stoichiometry: 1.0
species: 302538

719605
type: SpeciesReference
stoichiometry: 1.0
species: 302914

719569
type: SpeciesReference
stoichiometry: 1.0
species: 302928

303526
type: Reaction
product: 710416
reversible: true
name: _5,10-methylenetetrahydrofolate reductase (NADH)
reactant: 710379
reactant: 710392
product: 710404
kinetic law: 710428
reactant: 710366
fast: false
notes: Abbreviation: R_MTHFR2 Synonyms: _0 SUBSYSTEM: Folate Metabolism Equation: [c] : h + mlthf + nadh <==> 5mthf + nad Confidence Level: 2 tv genes: LOCUS:BLBBGE_445#ABBREVIATION:metF#ECNUMBERS:1.7.99.5# proteins: NAME:Methylenetetrahydrofolate reductase#ABBREVIATION:MetF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_445)

710416
type: SpeciesReference
stoichiometry: 1.0
species: 302719

710379
type: SpeciesReference
stoichiometry: 1.0
species: 302708

710392
type: SpeciesReference
stoichiometry: 1.0
species: 302720

710404
type: SpeciesReference
stoichiometry: 1.0
species: 302470

304889
type: LocalParameter
value: 0.0

304888
type: LocalParameter
value: 0.0

304887
type: LocalParameter
value: 999999.0

304886
type: LocalParameter
value: -999999.0

710366
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303438
type: Reaction
fast: false
name: HCO3 equilibration reaction
kinetic law: 707292
reactant: 707244
product: 707280
reversible: true
product: 707268
reactant: 707256
notes: Abbreviation: R_HCO3E Synonyms: _7 EC Number: 4.2.1.1 SUBSYSTEM: Unassigned Equation: [c] : co2 + h2o <==> h + hco3 Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:

304695
type: LocalParameter
value: 0.0

304694
type: LocalParameter
value: 0.0

304693
type: LocalParameter
value: 999999.0

304692
type: LocalParameter
value: -999999.0

707244
type: SpeciesReference
stoichiometry: 1.0
species: 302536

707280
type: SpeciesReference
stoichiometry: 1.0
species: 302662

707268
type: SpeciesReference
stoichiometry: 1.0
species: 302659

707256
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303298
type: Reaction
kinetic law: 703677
product: 703665
reactant: 703653
notes: Abbreviation: R_EX_gln_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : gln-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Glutamine exchange

304390
type: LocalParameter
value: 0.0

304389
type: LocalParameter
value: 0.0

304388
type: LocalParameter
value: 999999.0

304386
type: LocalParameter
value: -999999.0

703665
type: SpeciesReference
stoichiometry: 1.0
species: 303024

703653
type: SpeciesReference
stoichiometry: 1.0
species: 302629

303431
type: Reaction
name: GTP cyclohydrolase II (25drapp)
kinetic law: 707124
notes: Abbreviation: R_GTPCII2 Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : gtp + (3) h2o --> 25drapp + for + (2) h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_323#ABBREVIATION:ribBA#ECNUMBERS:3.5.4.25,-!-,4.1.99.12# proteins: NAME:_bifunctional 3,4 dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II#ABBREVIATION:RibBA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_323)
reversible: false
product: 707075
product: 707099
product: 707112
fast: false
product: 707087
reactant: 707063
reactant: 707051

304683
type: LocalParameter
value: 0.0

304682
type: LocalParameter
value: 0.0

304681
type: LocalParameter
value: 999999.0

304680
type: LocalParameter
value: 0.0

707075
type: SpeciesReference
stoichiometry: 1.0
species: 302415

707099
type: SpeciesReference
stoichiometry: 2.0
species: 302659

707112
type: SpeciesReference
stoichiometry: 1.0
species: 302865

707087
type: SpeciesReference
stoichiometry: 1.0
species: 302608

707063
type: SpeciesReference
stoichiometry: 3.0
species: 302655

707051
type: SpeciesReference
stoichiometry: 1.0
species: 302651

303744
type: Reaction
reactant: 718721
fast: false
kinetic law: 718771
product: 718745
name: shikimate kinase
product: 718758
product: 718733
notes: Abbreviation: R_SHKK Synonyms: _0 EC Number: 2.7.1.71 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : atp + skm --> adp + h + skm5p Confidence Level: 2 genes: LOCUS:BLBBGE_430#ABBREVIATION:aroK#ECNUMBERS:2.7.1.71# proteins: NAME:Skikimic acid kinase I#ABBREVIATION:AroK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_430)
reversible: false
reactant: 718709

718721
type: SpeciesReference
stoichiometry: 1.0
species: 302910

305584
type: LocalParameter
value: 0.0

305583
type: LocalParameter
value: 0.0

305582
type: LocalParameter
value: 999999.0

305581
type: LocalParameter
value: 0.0

718745
type: SpeciesReference
stoichiometry: 1.0
species: 302659

718758
type: SpeciesReference
stoichiometry: 1.0
species: 302909

718733
type: SpeciesReference
stoichiometry: 1.0
species: 302493

718709
type: SpeciesReference
stoichiometry: 1.0
species: 302526

303627
type: Reaction
reactant: 713708
reactant: 713720
name: _2-Oxo-4-methyl-3-carboxypentanoate decarboxylation
kinetic law: 713756
reversible: false
notes: Abbreviation: R_OMCDC Synonyms: _0 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 3c4mop + h --> 4mop + co2 Confidence Level: 2 Continuation of EC 1.1.1.85 reaction genes: LOCUS:BLBBGE_070#ABBREVIATION:leuB#ECNUMBERS:1.1.1.85# proteins: NAME:Isopropylmalate dehydrogenase#ABBREVIATION:LeuB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_070)
fast: false
product: 713732
product: 713744

713708
type: SpeciesReference
stoichiometry: 1.0
species: 302437

713720
type: SpeciesReference
stoichiometry: 1.0
species: 302659

305215
type: LocalParameter
value: 0.0

305214
type: LocalParameter
value: 0.0

305213
type: LocalParameter
value: 999999.0

305212
type: LocalParameter
value: 0.0

713732
type: SpeciesReference
stoichiometry: 1.0
species: 302454

713744
type: SpeciesReference
stoichiometry: 1.0
species: 302536

303084
type: Reaction
kinetic law: 695215
product: 695191
product: 695203
reversible: false
name: Acetyl-CoA ACP transacylase
fast: false
reactant: 695179
notes: Abbreviation: R_ACOATA Synonyms: _0 EC Number: 2.3.1.38 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : ACP + accoa --> acACP + coa Confidence Level: 2 tvrxn is now charge balanced; removed h - NCD genes: LOCUS:BLBBGE_111#ABBREVIATION:fabH#ECNUMBERS:2.3.1.41# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase#ABBREVIATION:FabH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_111)
reactant: 695167

303840
type: LocalParameter
value: 0.0

303839
type: LocalParameter
value: 0.0

303838
type: LocalParameter
value: 999999.0

303837
type: LocalParameter
value: 0.0

695191
type: SpeciesReference
stoichiometry: 1.0
species: 302478

695203
type: SpeciesReference
stoichiometry: 1.0
species: 302538

695179
type: SpeciesReference
stoichiometry: 1.0
species: 302479

695167
type: SpeciesReference
stoichiometry: 1.0
species: 302487

303450
type: Reaction
name: homoserine dehydrogenase (NADPH)
fast: false
notes: Abbreviation: R_HSDy Synonyms: _0 EC Number: 1.1.1.3 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : aspsa + h + nadph --> hom-L + nadp Confidence Level: 2 genes: LOCUS:BLBBGE_501#ABBREVIATION:thrA#ECNUMBERS:2.7.2.4,-!-,1.1.1.3# proteins: NAME:Homoserine dehydrogenase#ABBREVIATION:MetL# NAME:Aspartate kinase I#ABBREVIATION:ThrA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_501)
product: 707725
reactant: 707677
reactant: 707689
reversible: false
reactant: 707701
product: 707713
kinetic law: 707737

707725
type: SpeciesReference
stoichiometry: 1.0
species: 302723

707677
type: SpeciesReference
stoichiometry: 1.0
species: 302524

707689
type: SpeciesReference
stoichiometry: 1.0
species: 302659

707701
type: SpeciesReference
stoichiometry: 1.0
species: 302724

707713
type: SpeciesReference
stoichiometry: 1.0
species: 302672

304721
type: LocalParameter
value: 0.0

304720
type: LocalParameter
value: 0.0

304719
type: LocalParameter
value: 999999.0

304718
type: LocalParameter
value: 0.0

303166
type: Reaction
reactant: 698909
product: 698957
reactant: 698945
fast: false
reversible: false
product: 698970
name: Fatty acid biosynthesis (n-C12:0)
product: 698982
reactant: 698933
product: 699007
product: 698994
reactant: 698921
notes: Abbreviation: R_C120SN Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : actACP + (14) h + (4) malACP + (10) nadph --> (4) ACP + (4) co2 + ddcaACP + (5) h2o + (10) nadp Confidence Level: 2 TV, JRNeidhard pg. 615 genes: LOCUS:BLBBGE_037#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-# LOCUS:BLBBGE_346#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9# LOCUS:BLBBGE_057#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100# LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.179# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabG# NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI# NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_037) and (BLBBGE_079) and (BLBBGE_346) and (BLBBGE_057)
kinetic law: 699019

698909
type: SpeciesReference
stoichiometry: 1.0
species: 302489

698957
type: SpeciesReference
stoichiometry: 4.0
species: 302487

698945
type: SpeciesReference
stoichiometry: 10.0
species: 302724

698970
type: SpeciesReference
stoichiometry: 4.0
species: 302536

698982
type: SpeciesReference
stoichiometry: 1.0
species: 302560

698933
type: SpeciesReference
stoichiometry: 4.0
species: 302697

699007
type: SpeciesReference
stoichiometry: 10.0
species: 302723

698994
type: SpeciesReference
stoichiometry: 5.0
species: 302655

698921
type: SpeciesReference
stoichiometry: 14.0
species: 302659

304068
type: LocalParameter
value: 0.0

304067
type: LocalParameter
value: 0.0

304066
type: LocalParameter
value: 999999.0

304064
type: LocalParameter
value: 0.0

303717
type: Reaction
product: 717297
reactant: 717285
kinetic law: 717334
name: pyridoxamine 5'-phosphate oxidase
product: 717309
fast: false
reactant: 717273
product: 717321
reversible: false
notes: Abbreviation: R_PYAM5PO Synonyms: _0 EC Number: 1.4.3.5 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : h2o + o2 + pyam5p --> h2o2 + nh4 + pydx5p Confidence Level: 2 NCD genes: LOCUS:BLBBGE_050#ABBREVIATION:pdxH#ECNUMBERS:1.4.3.5# proteins: NAME:Pyridoxine 5-phosphate oxidase#ABBREVIATION:PdxH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_050)
reactant: 717261

717297
type: SpeciesReference
stoichiometry: 1.0
species: 302654

717285
type: SpeciesReference
stoichiometry: 1.0
species: 302888

305478
type: LocalParameter
value: 0.0

305476
type: LocalParameter
value: 0.0

305475
type: LocalParameter
value: 999999.0

305473
type: LocalParameter
value: 0.0

717309
type: SpeciesReference
stoichiometry: 1.0
species: 302725

717273
type: SpeciesReference
stoichiometry: 1.0
species: 302733

717321
type: SpeciesReference
stoichiometry: 1.0
species: 302889

717261
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303490
type: Reaction
notes: Abbreviation: R_KAS14 Synonyms: _0 EC Number: 2.3.1.41 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : acACP + h + malACP --> ACP + actACP + co2 Confidence Level: 2 tvAMF genes: LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.179# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_079)
product: 709037
kinetic law: 709062
product: 709025
reactant: 709001
reactant: 708989
product: 709050
name: beta-ketoacyl-ACP synthase
reactant: 709013
reversible: false
fast: false

709037
type: SpeciesReference
stoichiometry: 1.0
species: 302489

304809
type: LocalParameter
value: 0.0

304808
type: LocalParameter
value: 0.0

304807
type: LocalParameter
value: 999999.0

304806
type: LocalParameter
value: 0.0

709025
type: SpeciesReference
stoichiometry: 1.0
species: 302487

709001
type: SpeciesReference
stoichiometry: 1.0
species: 302659

708989
type: SpeciesReference
stoichiometry: 1.0
species: 302478

709050
type: SpeciesReference
stoichiometry: 1.0
species: 302536

709013
type: SpeciesReference
stoichiometry: 1.0
species: 302697

303771
type: Reaction
product: 720234
notes: Abbreviation: R_TMDPP Synonyms: _0 EC Number: 2.4.2.4 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : pi + thymd <==> 2dr1p + thym Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
reactant: 720198
kinetic law: 720246
name: thymidine phosphorylase
product: 720222
reactant: 720210

720234
type: SpeciesReference
stoichiometry: 1.0
species: 302944

720198
type: SpeciesReference
stoichiometry: 1.0
species: 302853

305688
type: LocalParameter
value: 0.0

305686
type: LocalParameter
value: 0.0

305685
type: LocalParameter
value: 999999.0

305683
type: LocalParameter
value: -999999.0

720222
type: SpeciesReference
stoichiometry: 1.0
species: 302425

720210
type: SpeciesReference
stoichiometry: 1.0
species: 302945

303710
type: Reaction
reactant: 716910
kinetic law: 716947
reactant: 716898
name: purine-nucleoside phosphorylase (Deoxyadenosine)
notes: Abbreviation: R_PUNP2 Synonyms: _0 EC Number: 2.4.2.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dad-2 + pi <==> 2dr1p + ade Confidence Level: 2 Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase genes: LOCUS:BLBBGE_377#ABBREVIATION:pndA#ECNUMBERS:2.4.2.1# proteins: NAME:purine-nucleoside phosphorylase#ABBREVIATION:PndA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)
reversible: true
product: 716934
product: 716922
fast: false

716910
type: SpeciesReference
stoichiometry: 1.0
species: 302853

305448
type: LocalParameter
value: 0.0

305447
type: LocalParameter
value: 0.0

305446
type: LocalParameter
value: 999999.0

305445
type: LocalParameter
value: -999999.0

716898
type: SpeciesReference
stoichiometry: 1.0
species: 302547

716934
type: SpeciesReference
stoichiometry: 1.0
species: 302490

716922
type: SpeciesReference
stoichiometry: 1.0
species: 302425

303338
type: Reaction
kinetic law: 704405
product: 704393
reactant: 704381
notes: Abbreviation: R_EX_pi_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : pi <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Phosphate exchange

304480
type: LocalParameter
value: 0.0

304479
type: LocalParameter
value: 0.0

304478
type: LocalParameter
value: 999999.0

304476
type: LocalParameter
value: -999999.0

704393
type: SpeciesReference
stoichiometry: 1.0
species: 303056

303056
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Phosphate_HO4P

704381
type: SpeciesReference
stoichiometry: 1.0
species: 302855

303073
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Tyrosine_C9H11NO3

303151
type: Reaction
reactant: 697822
fast: false
product: 697834
notes: Abbreviation: R_ASAD Synonyms: _0 EC Number: 1.2.1.11 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : 4pasp + h + nadph --> aspsa + nadp + pi Confidence Level: 2 genes: LOCUS:BLBBGE_299#ABBREVIATION:asd#ECNUMBERS:1.2.1.11# proteins: NAME:Aspartate-semialdehyde dehydrogenase#ABBREVIATION:Asd# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_299)
name: aspartate-semialdehyde dehydrogenase
reactant: 697798
kinetic law: 697870
reversible: false
reactant: 697810
product: 697858
product: 697846

697822
type: SpeciesReference
stoichiometry: 1.0
species: 302724

697834
type: SpeciesReference
stoichiometry: 1.0
species: 302524

697798
type: SpeciesReference
stoichiometry: 1.0
species: 302455

304026
type: LocalParameter
value: 0.0

304025
type: LocalParameter
value: 0.0

304024
type: LocalParameter
value: 999999.0

304023
type: LocalParameter
value: 0.0

697810
type: SpeciesReference
stoichiometry: 1.0
species: 302659

697858
type: SpeciesReference
stoichiometry: 1.0
species: 302853

697846
type: SpeciesReference
stoichiometry: 1.0
species: 302723

303206
type: Reaction
product: 700825
kinetic law: 700837
product: 700812
notes: Abbreviation: R_CYTK2 Synonyms: _0 EC Number: 2.7.4.14 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dcmp <==> adp + dcdp Confidence Level: 2 genes: LOCUS:BLBBGE_058#ABBREVIATION:cmk#ECNUMBERS:2.7.4.14# proteins: NAME:cytidine monophosphate kinase#ABBREVIATION:Cmk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_058)
name: cytidylate kinase (dCMP)
reactant: 700787
fast: false
reversible: true
reactant: 700800

700825
type: SpeciesReference
stoichiometry: 1.0
species: 302555

304164
type: LocalParameter
value: 0.0

304163
type: LocalParameter
value: 0.0

304162
type: LocalParameter
value: 999999.0

304161
type: LocalParameter
value: -999999.0

700812
type: SpeciesReference
stoichiometry: 1.0
species: 302493

700787
type: SpeciesReference
stoichiometry: 1.0
species: 302526

700800
type: SpeciesReference
stoichiometry: 1.0
species: 302556

303519
type: Reaction
fast: false
kinetic law: 710225
product: 710213
reversible: false
product: 710189
product: 710201
reactant: 710165
name: _mevalonate kinase
notes: Abbreviation: R_MEVK1x Synonyms: _0 EC Number: 2.7.1.36 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c]: atp + mev-R --> 5pmev + adp + (2) h Confidence Level: 2 genes: LOCUS:BLBBGE_085#ABBREVIATION:mvaK#ECNUMBERS:2.7.1.36# proteins: NAME:_mevalonate kinase#ABBREVIATION:MvaK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_085)
reactant: 710177

304877
type: LocalParameter
value: 0.0

304876
type: LocalParameter
value: 0.0

304875
type: LocalParameter
value: 999999.0

304873
type: LocalParameter
value: 0.0

710213
type: SpeciesReference
stoichiometry: 2.0
species: 302659

710189
type: SpeciesReference
stoichiometry: 1.0
species: 302493

710201
type: SpeciesReference
stoichiometry: 1.0
species: 302472

710165
type: SpeciesReference
stoichiometry: 1.0
species: 302526

710177
type: SpeciesReference
stoichiometry: 1.0
species: 302706

303530
type: Reaction
kinetic law: 710526
product: 710514
reactant: 710502
notes: Abbreviation: R_NACUP Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: nac[e] --> nac[c] Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: false
name: Nicotinic acid uptake

304899
type: LocalParameter
value: 0.0

304898
type: LocalParameter
value: 0.0

304897
type: LocalParameter
value: 999999.0

304896
type: LocalParameter
value: 0.0

710514
type: SpeciesReference
stoichiometry: 1.0
species: 302717

302717
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Nicotinate_C6H4NO2

710502
type: SpeciesReference
stoichiometry: 1.0
species: 302718

303442
type: Reaction
product: 707437
product: 707461
reversible: false
fast: false
reactant: 707413
notes: Abbreviation: R_HISTD Synonyms: _0 EC Number: 1.1.1.23 SUBSYSTEM: Histidine Metabolism Equation: [c] : h2o + histd + (2) nad --> (3) h + his-L + (2) nadh Confidence Level: 2 genes: LOCUS:BLBBGE_434#ABBREVIATION:hisD#ECNUMBERS:1.1.1.23# proteins: NAME:Histidinol dehydrogenase#ABBREVIATION:HisD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_434)
product: 707449
reactant: 707425
name: histidinol dehydrogenase
kinetic law: 707473
reactant: 707401

707437
type: SpeciesReference
stoichiometry: 3.0
species: 302659

707461
type: SpeciesReference
stoichiometry: 2.0
species: 302720

707413
type: SpeciesReference
stoichiometry: 1.0
species: 302670

707449
type: SpeciesReference
stoichiometry: 1.0
species: 302666

707425
type: SpeciesReference
stoichiometry: 2.0
species: 302719

304705
type: LocalParameter
value: 0.0

304704
type: LocalParameter
value: 0.0

304703
type: LocalParameter
value: 999999.0

304701
type: LocalParameter
value: 0.0

707401
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303695
type: Reaction
product: 716116
kinetic law: 716152
fast: false
reactant: 716104
product: 716140
notes: Abbreviation: R_PRATPP Synonyms: _0 EC Number: 3.6.1.31 SUBSYSTEM: Histidine Metabolism Equation: [c] : h2o + prbatp --> h + ppi + prbamp Confidence Level: 2 genes: LOCUS:BLBBGE_440#ABBREVIATION:hisI#ECNUMBERS:3.5.4.19,-!-,3.6.1.31# proteins: NAME:Phosphoribosyl-ATP pyrophosphatase and -AMP cyclohydrolase#ABBREVIATION:HisI# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_440)
reactant: 716092
reversible: false
product: 716128
name: phosphoribosyl-ATP pyrophosphatase

716116
type: SpeciesReference
stoichiometry: 1.0
species: 302659

305388
type: LocalParameter
value: 0.0

305387
type: LocalParameter
value: 0.0

305386
type: LocalParameter
value: 999999.0

305385
type: LocalParameter
value: 0.0

716104
type: SpeciesReference
stoichiometry: 1.0
species: 302873

716140
type: SpeciesReference
stoichiometry: 1.0
species: 302870

716092
type: SpeciesReference
stoichiometry: 1.0
species: 302655

716128
type: SpeciesReference
stoichiometry: 1.0
species: 302865

303248
type: Reaction
kinetic law: 702349
product: 702337
product: 702325
reactant: 702313
notes: Abbreviation: R_DHQS Synonyms: _0 EC Number: 4.2.3.4 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : 2dda7p --> 3dhq + pi Confidence Level: 2 Previously EC 4.6.1.3. now EC 4.2.3.4, 3-dehydroquinate synthase genes: LOCUS:BLBBGE_493#ABBREVIATION:aroB#ECNUMBERS:4.6.1.3# proteins: NAME:_3-dehydroquinate synthase#ABBREVIATION:AroB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_493)
fast: false
reversible: false
name: _3-dehydroquinate synthase

304272
type: LocalParameter
value: 0.0

304271
type: LocalParameter
value: 0.0

304270
type: LocalParameter
value: 999999.0

304268
type: LocalParameter
value: 0.0

702337
type: SpeciesReference
stoichiometry: 1.0
species: 302853

702325
type: SpeciesReference
stoichiometry: 1.0
species: 302438

702313
type: SpeciesReference
stoichiometry: 1.0
species: 302421

303709
type: Reaction
fast: false
reactant: 716838
reactant: 716850
name: purine-nucleoside phosphorylase (Adenosine)
product: 716862
product: 716874
notes: Abbreviation: R_PUNP1 Synonyms: _0 EC Number: 2.4.2.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : adn + pi <==> ade + r1p Confidence Level: 2 Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase genes: LOCUS:BLBBGE_377#ABBREVIATION:pndA#ECNUMBERS:2.4.2.1# proteins: NAME:purine-nucleoside phosphorylase#ABBREVIATION:PndA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)
reversible: true
kinetic law: 716886

716838
type: SpeciesReference
stoichiometry: 1.0
species: 302492

716850
type: SpeciesReference
stoichiometry: 1.0
species: 302853

716862
type: SpeciesReference
stoichiometry: 1.0
species: 302490

716874
type: SpeciesReference
stoichiometry: 1.0
species: 302895

305444
type: LocalParameter
value: 0.0

305442
type: LocalParameter
value: 0.0

305441
type: LocalParameter
value: 999999.0

305439
type: LocalParameter
value: -999999.0

303763
type: Reaction
kinetic law: 719860
product: 719847
product: 719835
reactant: 719823
notes: Abbreviation: R_THRD_L Synonyms: _1 EC Number: 4.3.1.19 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : thr-L --> 2obut + nh4 Confidence Level: 2 Previous EC number: 4.2.1.16. New EC number 4.3.1.19. Can't enter this.... genes: LOCUS:BLBBGE_553#ABBREVIATION:ilvA#ECNUMBERS:4.3.1.19# proteins: NAME:threonine deaminase#ABBREVIATION:IlvA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_553)
fast: false
reversible: false
name: L-threonine deaminase

305658
type: LocalParameter
value: 0.0

305656
type: LocalParameter
value: 0.0

305655
type: LocalParameter
value: 999999.0

305653
type: LocalParameter
value: 0.0

719847
type: SpeciesReference
stoichiometry: 1.0
species: 302725

719835
type: SpeciesReference
stoichiometry: 1.0
species: 302427

719823
type: SpeciesReference
stoichiometry: 1.0
species: 302940

303346
type: Reaction
kinetic law: 704552
product: 704540
reactant: 704528
notes: Abbreviation: R_EX_pyr_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : pyr <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Pyruvate exchange

304498
type: LocalParameter
value: 0.0

304497
type: LocalParameter
value: 0.0

304496
type: LocalParameter
value: 999999.0

304495
type: LocalParameter
value: 0.0

704540
type: SpeciesReference
stoichiometry: 1.0
species: 303062

704528
type: SpeciesReference
stoichiometry: 1.0
species: 302894

303447
type: Reaction
kinetic law: 707665
name: _6-hydroxymethyl-dihydropterin pyrophosphokinase
notes: Abbreviation: R_HPPK2 Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 6hmhpt + atp --> 6hmhptpp + amp + h Confidence Level: 2 JLR- Neidhardt pg 667 genes: LOCUS:BLBBGE_627#ABBREVIATION:folK#ECNUMBERS:2.7.6.3# proteins: NAME:_7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase#ABBREVIATION:FolK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_627)
product: 707653
reactant: 707617
reactant: 707605
fast: false
product: 707641
product: 707629
reversible: false

304717
type: LocalParameter
value: 0.0

304716
type: LocalParameter
value: 0.0

304715
type: LocalParameter
value: 999999.0

304714
type: LocalParameter
value: 0.0

707653
type: SpeciesReference
stoichiometry: 1.0
species: 302659

707617
type: SpeciesReference
stoichiometry: 1.0
species: 302526

707605
type: SpeciesReference
stoichiometry: 1.0
species: 302473

707641
type: SpeciesReference
stoichiometry: 1.0
species: 302511

707629
type: SpeciesReference
stoichiometry: 1.0
species: 302474

303736
type: Reaction
product: 718298
product: 718286
notes: Abbreviation: R_SDPTA Synonyms: _0 EC Number: 2.6.1.17 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : akg + sl26da <==> glu-L + sl2a6o Confidence Level: 2 genes: LOCUS:BLBBGE_315#ABBREVIATION:dapC#ECNUMBERS:2.6.1.11,-!-,2.6.1.17# LOCUS:BLBBGE_623#ABBREVIATION:dapC#ECNUMBERS:2.6.1.11,-!-,2.6.1.17# proteins: NAME:bifunctional acetylornithine transaminase/N-succinyldiaminopimelate aminotransferase#ABBREVIATION:DapC# NAME:N-succinyldiaminopimelate aminotransferase#ABBREVIATION:DapC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_315) or (BLBBGE_623)
name: succinyldiaminopimelate transaminase
reactant: 718274
reactant: 718262
reversible: true
fast: false
kinetic law: 718311

718298
type: SpeciesReference
stoichiometry: 1.0
species: 302914

718286
type: SpeciesReference
stoichiometry: 1.0
species: 302633

718274
type: SpeciesReference
stoichiometry: 1.0
species: 302913

718262
type: SpeciesReference
stoichiometry: 1.0
species: 302500

305550
type: LocalParameter
value: 0.0

305549
type: LocalParameter
value: 0.0

305548
type: LocalParameter
value: 999999.0

305547
type: LocalParameter
value: -999999.0

303631
type: Reaction
product: 713866
product: 713854
reactant: 713842
notes: Abbreviation: R_ORPT Synonyms: _0 EC Number: 2.4.2.10 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : orot + prpp --> orot5p + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_512#ABBREVIATION:pyrFE#ECNUMBERS:2.4.2.10# proteins: NAME:Orotidine 5'-phosphate decarboxylase-Orotate phosphoribosyltransferase#ABBREVIATION:PyrFE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_512)
kinetic law: 713878
reactant: 713830
reversible: false
fast: false
name: orotate phosphoribosyltransferase

713866
type: SpeciesReference
stoichiometry: 1.0
species: 302865

713854
type: SpeciesReference
stoichiometry: 1.0
species: 302745

713842
type: SpeciesReference
stoichiometry: 1.0
species: 302880

305223
type: LocalParameter
value: 0.0

305222
type: LocalParameter
value: 0.0

305221
type: LocalParameter
value: 999999.0

305220
type: LocalParameter
value: 0.0

713830
type: SpeciesReference
stoichiometry: 1.0
species: 302748

303487
type: Reaction
reversible: false
reactant: 708941
notes: Abbreviation: R_KARA2i Synonyms: _0 EC Number: 1.1.1.86 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 2ahbut + h + nadph --> 23dhmp + nadp Confidence Level: 2 JLR - added irreversible form of KARA2 genes: LOCUS:BLBBGE_554#ABBREVIATION:ilvC#ECNUMBERS:1.1.1.86# proteins: NAME:acetohydroxy acid isomeroreductase#ABBREVIATION:IlvC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_554)
product: 708965
reactant: 708916
reactant: 708928
kinetic law: 708977
name: ketol-acid reductoisomerase (2-Aceto-2-hydroxybutanoate)
fast: false
product: 708953

708941
type: SpeciesReference
stoichiometry: 1.0
species: 302724

708965
type: SpeciesReference
stoichiometry: 1.0
species: 302723

708916
type: SpeciesReference
stoichiometry: 1.0
species: 302418

708928
type: SpeciesReference
stoichiometry: 1.0
species: 302659

304805
type: LocalParameter
value: 0.0

304804
type: LocalParameter
value: 0.0

304803
type: LocalParameter
value: 999999.0

304801
type: LocalParameter
value: 0.0

708953
type: SpeciesReference
stoichiometry: 1.0
species: 302412

303148
type: Reaction
product: 697774
product: 697749
fast: false
name: argininosuccinate synthase
reactant: 697701
kinetic law: 697786
product: 697737
notes: Abbreviation: R_ARGSS Synonyms: _0 EC Number: 6.3.4.5 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : asp-L + atp + citr-L --> amp + argsuc + h + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_313#ABBREVIATION:argG#ECNUMBERS:6.3.4.5# proteins: NAME:argininosuccinate synthetase#ABBREVIATION:ArgG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_313)
product: 697761
reactant: 697725
reversible: false
reactant: 697713

697774
type: SpeciesReference
stoichiometry: 1.0
species: 302865

697749
type: SpeciesReference
stoichiometry: 1.0
species: 302518

697701
type: SpeciesReference
stoichiometry: 1.0
species: 302522

304022
type: LocalParameter
value: 0.0

304021
type: LocalParameter
value: 0.0

304020
type: LocalParameter
value: 999999.0

304019
type: LocalParameter
value: 0.0

697737
type: SpeciesReference
stoichiometry: 1.0
species: 302511

697761
type: SpeciesReference
stoichiometry: 1.0
species: 302659

697725
type: SpeciesReference
stoichiometry: 1.0
species: 302533

697713
type: SpeciesReference
stoichiometry: 1.0
species: 302526

303721
type: Reaction
kinetic law: 717527
notes: Abbreviation: R_PYRt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h[e] + pyr[e] <==> h[c] + pyr[c] Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
product: 717515
reactant: 717491
reactant: 717479
fast: false
product: 717503
reversible: true
name: pyruvate reversible transport via proton symport

305490
type: LocalParameter
value: 0.0

305489
type: LocalParameter
value: 0.0

305488
type: LocalParameter
value: 999999.0

305487
type: LocalParameter
value: -999999.0

717515
type: SpeciesReference
stoichiometry: 1.0
species: 302893

717491
type: SpeciesReference
stoichiometry: 1.0
species: 302894

717479
type: SpeciesReference
stoichiometry: 1.0
species: 302660

717503
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303234
type: Reaction
notes: Abbreviation: R_DHFS Synonyms: _0 EC Number: 6.3.2.12 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + dhpt + glu-L --> adp + dhf + pi Confidence Level: 2 genes: LOCUS:BLBBGE_182#ABBREVIATION:folC#ECNUMBERS:6.3.2.12,-!-,6.3.2.17# proteins: NAME:folypolyglutamate synthase and dihydrofolate synthase#ABBREVIATION:FolC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_182)
fast: false
product: 701841
reactant: 701805
product: 701866
name: dihydrofolate synthase
reactant: 701817
reversible: false
reactant: 701829
kinetic law: 701878
product: 701853

701841
type: SpeciesReference
stoichiometry: 1.0
species: 302493

701805
type: SpeciesReference
stoichiometry: 1.0
species: 302526

701866
type: SpeciesReference
stoichiometry: 1.0
species: 302853

701817
type: SpeciesReference
stoichiometry: 1.0
species: 302575

701829
type: SpeciesReference
stoichiometry: 1.0
species: 302633

304234
type: LocalParameter
value: 0.0

304233
type: LocalParameter
value: 0.0

304232
type: LocalParameter
value: 999999.0

304231
type: LocalParameter
value: 0.0

701853
type: SpeciesReference
stoichiometry: 1.0
species: 302567

303357
type: Reaction
kinetic law: 704744
product: 704732
reactant: 704719
notes: Abbreviation: R_EX_thr_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : thr-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Threonine exchange

304520
type: LocalParameter
value: 0.0

304519
type: LocalParameter
value: 0.0

304518
type: LocalParameter
value: 999999.0

304517
type: LocalParameter
value: 0.0

704732
type: SpeciesReference
stoichiometry: 1.0
species: 303071

704719
type: SpeciesReference
stoichiometry: 1.0
species: 302943

303193
type: Reaction
product: 700331
kinetic law: 700343
reactant: 700271
reactant: 700259
fast: false
product: 700307
reversible: false
notes: Abbreviation: R_CYSabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + cys-L[e] + h2o[c] --> adp[c] + cys-L[c] + h[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 700319
reactant: 700283
name: L-cysteine transport via ABC system
product: 700295

700331
type: SpeciesReference
stoichiometry: 1.0
species: 302853

304134
type: LocalParameter
value: 0.0

304133
type: LocalParameter
value: 0.0

304132
type: LocalParameter
value: 999999.0

304131
type: LocalParameter
value: 0.0

700271
type: SpeciesReference
stoichiometry: 1.0
species: 302543

700259
type: SpeciesReference
stoichiometry: 1.0
species: 302526

700307
type: SpeciesReference
stoichiometry: 1.0
species: 302542

700319
type: SpeciesReference
stoichiometry: 1.0
species: 302659

700283
type: SpeciesReference
stoichiometry: 1.0
species: 302655

700295
type: SpeciesReference
stoichiometry: 1.0
species: 302493

303439
type: Reaction
reversible: false
name: L-histidine transport via ABC system
product: 707377
product: 707365
fast: false
notes: Abbreviation: R_HISabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + his-L[e] --> adp[c] + h[c] + his-L[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 707316
reactant: 707304
product: 707340
reactant: 707328
kinetic law: 707389
product: 707353

707377
type: SpeciesReference
stoichiometry: 1.0
species: 302853

707365
type: SpeciesReference
stoichiometry: 1.0
species: 302666

707316
type: SpeciesReference
stoichiometry: 1.0
species: 302655

707304
type: SpeciesReference
stoichiometry: 1.0
species: 302526

707340
type: SpeciesReference
stoichiometry: 1.0
species: 302493

707328
type: SpeciesReference
stoichiometry: 1.0
species: 302667

304699
type: LocalParameter
value: 0.0

304698
type: LocalParameter
value: 0.0

304697
type: LocalParameter
value: 999999.0

304696
type: LocalParameter
value: 0.0

707353
type: SpeciesReference
stoichiometry: 1.0
species: 302659

303102
type: Reaction
kinetic law: 695819
product: 695807
reactant: 695795
reactant: 695783
notes: Abbreviation: R_ADK1 Synonyms: _0 EC Number: 2.7.4.3 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : amp + atp <==> (2) adp Confidence Level: 2 Inorganic triphosphate can also act as donor genes: LOCUS:BLBBGE_215#ABBREVIATION:adk#ECNUMBERS:2.7.4.3# proteins: NAME:Adenylate kinase#ABBREVIATION:Adk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_215)
fast: false
reversible: true
name: adenylate kinase

303886
type: LocalParameter
value: 0.0

303885
type: LocalParameter
value: 0.0

303884
type: LocalParameter
value: 999999.0

303883
type: LocalParameter
value: -999999.0

695807
type: SpeciesReference
stoichiometry: 2.0
species: 302493

695795
type: SpeciesReference
stoichiometry: 1.0
species: 302526

695783
type: SpeciesReference
stoichiometry: 1.0
species: 302511

303350
type: Reaction
kinetic law: 704628
product: 704615
reactant: 704602
notes: Abbreviation: R_EX_so4_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : so4 <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Sulfate exchange

304506
type: LocalParameter
value: 0.0

304505
type: LocalParameter
value: 0.0

304504
type: LocalParameter
value: 999999.0

304503
type: LocalParameter
value: -999999.0

704615
type: SpeciesReference
stoichiometry: 1.0
species: 303066

704602
type: SpeciesReference
stoichiometry: 1.0
species: 302919

303211
type: Reaction
kinetic law: 701030
product: 701018
reversible: false
name: diaminopimelate decarboxylase
reactant: 700982
notes: Abbreviation: R_DAPDC Synonyms: _0 EC Number: 4.1.1.20 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : 26dap-M + h --> co2 + lys-L Confidence Level: 2 genes: LOCUS:BLBBGE_331#ABBREVIATION:lysA#ECNUMBERS:4.1.1.20# proteins: NAME:Diaminopimelate decarboxylase#ABBREVIATION:LysA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_331)
reactant: 700994
product: 701006
fast: false

304178
type: LocalParameter
value: 0.0

304177
type: LocalParameter
value: 0.0

304176
type: LocalParameter
value: 999999.0

304175
type: LocalParameter
value: 0.0

701018
type: SpeciesReference
stoichiometry: 1.0
species: 302694

700982
type: SpeciesReference
stoichiometry: 1.0
species: 302417

700994
type: SpeciesReference
stoichiometry: 1.0
species: 302659

701006
type: SpeciesReference
stoichiometry: 1.0
species: 302536

303498
type: Reaction
product: 709364
reactant: 709339
product: 709376
reversible: true
name: potassium reversible transport via proton symport
reactant: 709351
notes: Abbreviation: R_Kt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h[e] + k[e] <==> h[c] + k[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_574#ABBREVIATION:ktrB# LOCUS:BLBBGE_575#ABBREVIATION:ktrA# proteins: NAME:K+ uptake transporter subunit KtrB#ABBREVIATION:KtrB# NAME:K+ uptake transporter subunit KtrA#ABBREVIATION:KtrA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_574) and (BLBBGE_575)
fast: false
kinetic law: 709388

709364
type: SpeciesReference
stoichiometry: 1.0
species: 302659

709339
type: SpeciesReference
stoichiometry: 1.0
species: 302660

709376
type: SpeciesReference
stoichiometry: 1.0
species: 302689

709351
type: SpeciesReference
stoichiometry: 1.0
species: 302691

304827
type: LocalParameter
value: 0.0

304826
type: LocalParameter
value: 0.0

304825
type: LocalParameter
value: 999999.0

304824
type: LocalParameter
value: -999999.0

303779
type: Reaction
kinetic law: 720674
product: 720661
product: 720648
reactant: 720635
notes: Abbreviation: R_TRPS3 Synonyms: _0 EC Number: 4.2.1.20 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : 3ig3p --> g3p + indole Confidence Level: 2 JLR genes: LOCUS:BLBBGE_426#ABBREVIATION:trpA#ECNUMBERS:4.2.1.20# LOCUS:BLBBGE_425#ABBREVIATION:trpB#ECNUMBERS:4.2.1.20# proteins: NAME:Tryptophan synthase#ABBREVIATION:TrpA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_426 and BLBBGE_425)
fast: false
reversible: false
name: tryptophan synthase (indoleglycerol phosphate)

305722
type: LocalParameter
value: 0.0

305720
type: LocalParameter
value: 0.0

305719
type: LocalParameter
value: 999999.0

305717
type: LocalParameter
value: 0.0

720661
type: SpeciesReference
stoichiometry: 1.0
species: 302684

720648
type: SpeciesReference
stoichiometry: 1.0
species: 302620

720635
type: SpeciesReference
stoichiometry: 1.0
species: 302442

303491
type: Reaction
reactant: 709074
fast: false
reactant: 709086
product: 709122
reversible: false
product: 709110
name: beta-ketoacyl-ACP synthase (2)
kinetic law: 709147
product: 709134
reactant: 709098
notes: Abbreviation: R_KAS15 Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : accoa + h + malACP --> actACP + co2 + coa Confidence Level: 2 tvAMF genes: LOCUS:BLBBGE_111#ABBREVIATION:fabH#ECNUMBERS:2.3.1.41# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase#ABBREVIATION:FabH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_111)

709074
type: SpeciesReference
stoichiometry: 1.0
species: 302479

709086
type: SpeciesReference
stoichiometry: 1.0
species: 302659

709122
type: SpeciesReference
stoichiometry: 1.0
species: 302536

709110
type: SpeciesReference
stoichiometry: 1.0
species: 302489

304813
type: LocalParameter
value: 0.0

304812
type: LocalParameter
value: 0.0

304811
type: LocalParameter
value: 999999.0

304810
type: LocalParameter
value: 0.0

709134
type: SpeciesReference
stoichiometry: 1.0
species: 302538

709098
type: SpeciesReference
stoichiometry: 1.0
species: 302697

303546
type: Reaction
notes: Abbreviation: R_NAMNPP Synonyms: _1 EC Number: 2.4.2.11 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + h2o + nac + prpp --> adp + nicrnt + pi + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_208#ABBREVIATION:pncB#ECNUMBERS:2.4.2.11# proteins: NAME:Nicotinate phosphoribosyltransferase#ABBREVIATION:PncB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_208)
fast: false
product: 711141
reactant: 711117
reactant: 711105
name: nicotinic acid mononucleotide pyrophosphorylase
reversible: false
product: 711177
reactant: 711093
product: 711165
kinetic law: 711189
reactant: 711129
product: 711153

711141
type: SpeciesReference
stoichiometry: 1.0
species: 302493

711117
type: SpeciesReference
stoichiometry: 1.0
species: 302717

711105
type: SpeciesReference
stoichiometry: 1.0
species: 302655

711177
type: SpeciesReference
stoichiometry: 1.0
species: 302865

711093
type: SpeciesReference
stoichiometry: 1.0
species: 302526

711165
type: SpeciesReference
stoichiometry: 1.0
species: 302853

304935
type: LocalParameter
value: 0.0

304934
type: LocalParameter
value: 0.0

304933
type: LocalParameter
value: 999999.0

304932
type: LocalParameter
value: 0.0

711129
type: SpeciesReference
stoichiometry: 1.0
species: 302880

711153
type: SpeciesReference
stoichiometry: 1.0
species: 302729

303458
type: Reaction
notes: Abbreviation: R_ICDHyr Synonyms: _0 EC Number: 1.1.1.42 SUBSYSTEM: Citric Acid Cycle Equation: [c] : icit + nadp --> akg + co2 + nadph Confidence Level: 2 Two reactions (ICDH1 and ICDH2) for isocitrate dehydrogenase genes: LOCUS:BLBBGE_272#ABBREVIATION:icd#ECNUMBERS:1.1.1.42# proteins: NAME:isocitrate dehydrogenase#ABBREVIATION:Icd# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_272)
reversible: false
fast: false
reactant: 707944
product: 707969
name: isocitrate dehydrogenase (NADP)
reactant: 707957
kinetic law: 708006
product: 707982
product: 707994

707944
type: SpeciesReference
stoichiometry: 1.0
species: 302676

707969
type: SpeciesReference
stoichiometry: 1.0
species: 302500

707957
type: SpeciesReference
stoichiometry: 1.0
species: 302723

304737
type: LocalParameter
value: 0.0

304736
type: LocalParameter
value: 0.0

304735
type: LocalParameter
value: 999999.0

304734
type: LocalParameter
value: 0.0

707982
type: SpeciesReference
stoichiometry: 1.0
species: 302536

707994
type: SpeciesReference
stoichiometry: 1.0
species: 302724

303152
type: Reaction
product: 697906
notes: Abbreviation: R_ASNt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: asn-L[e] + h[e] <==> asn-L[c] + h[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 697894
fast: false
name: L-asparagine reversible transport via proton symport
reversible: true
product: 697918
kinetic law: 697930
reactant: 697882

697906
type: SpeciesReference
stoichiometry: 1.0
species: 302519

697894
type: SpeciesReference
stoichiometry: 1.0
species: 302660

697918
type: SpeciesReference
stoichiometry: 1.0
species: 302659

304032
type: LocalParameter
value: 0.0

304031
type: LocalParameter
value: 0.0

304030
type: LocalParameter
value: 999999.0

304028
type: LocalParameter
value: -999999.0

697882
type: SpeciesReference
stoichiometry: 1.0
species: 302521

303170
type: Reaction
name: Fatty acid biosynthesis (n-C14:1)
notes: Abbreviation: R_C141SN Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : actACP + (16) h + (5) malACP + (11) nadph --> (5) ACP + (5) co2 + (6) h2o + (11) nadp + tdeACP Confidence Level: 2 tv genes: LOCUS:BLBBGE_037#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-# LOCUS:none#ABBREVIATION:fabA#ECNUMBERS:4.2.1.60# LOCUS:BLBBGE_346#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9# LOCUS:BLBBGE_057#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100# LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.179# LOCUS:BLBBGE_111#ABBREVIATION:fabH#ECNUMBERS:2.3.1.41# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase#ABBREVIATION:FabH# NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabG# NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI# NAME:beta-hydroxydecanoyl thioester dehydrase#ABBREVIATION:FabA# NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_037) and (BLBBGE_346) and (BLBBGE_057) and (BLBBGE_079) or (BLBBGE_111)
product: 699199
kinetic law: 699259
reactant: 699151
product: 699235
reversible: false
product: 699211
product: 699247
reactant: 699187
product: 699223
reactant: 699175
reactant: 699163
fast: false

699199
type: SpeciesReference
stoichiometry: 5.0
species: 302487

304076
type: LocalParameter
value: 0.0

304075
type: LocalParameter
value: 0.0

304074
type: LocalParameter
value: 999999.0

304073
type: LocalParameter
value: 0.0

699151
type: SpeciesReference
stoichiometry: 1.0
species: 302489

699235
type: SpeciesReference
stoichiometry: 11.0
species: 302723

699211
type: SpeciesReference
stoichiometry: 5.0
species: 302536

699247
type: SpeciesReference
stoichiometry: 1.0
species: 302930

699187
type: SpeciesReference
stoichiometry: 11.0
species: 302724

699223
type: SpeciesReference
stoichiometry: 6.0
species: 302655

699175
type: SpeciesReference
stoichiometry: 5.0
species: 302697

699163
type: SpeciesReference
stoichiometry: 16.0
species: 302659

303451
type: Reaction
product: 707773
reversible: false
product: 707785
product: 707798
name: homoserine kinase
reactant: 707761
reactant: 707749
notes: Abbreviation: R_HSK Synonyms: _0 EC Number: 2.7.1.39 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : atp + hom-L --> adp + h + phom Confidence Level: 2 genes: LOCUS:BLBBGE_500#ABBREVIATION:thrB#ECNUMBERS:2.7.1.39# proteins: NAME:Homoserine kinase#ABBREVIATION:ThrB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_500)
fast: false
kinetic law: 707810

707773
type: SpeciesReference
stoichiometry: 1.0
species: 302493

707785
type: SpeciesReference
stoichiometry: 1.0
species: 302659

707798
type: SpeciesReference
stoichiometry: 1.0
species: 302768

707761
type: SpeciesReference
stoichiometry: 1.0
species: 302672

707749
type: SpeciesReference
stoichiometry: 1.0
species: 302526

304725
type: LocalParameter
value: 0.0

304724
type: LocalParameter
value: 0.0

304723
type: LocalParameter
value: 999999.0

304722
type: LocalParameter
value: 0.0

303764
type: Reaction
fast: false
kinetic law: 719920
reversible: false
product: 719908
name: threonine synthase
product: 719896
notes: Abbreviation: R_THRS Synonyms: _0 EC Number: 4.2.3.1 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : h2o + phom --> pi + thr-L Confidence Level: 2 genes: LOCUS:BLBBGE_499#ABBREVIATION:thrC#ECNUMBERS:4.2.3.1# proteins: NAME:Threonine synthase#ABBREVIATION:ThrC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_499)
reactant: 719884
reactant: 719872

305662
type: LocalParameter
value: 0.0

305661
type: LocalParameter
value: 0.0

305660
type: LocalParameter
value: 999999.0

305659
type: LocalParameter
value: 0.0

719908
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stoichiometry: 1.0
species: 302940

719896
type: SpeciesReference
stoichiometry: 1.0
species: 302853

719884
type: SpeciesReference
stoichiometry: 1.0
species: 302768

719872
type: SpeciesReference
stoichiometry: 1.0
species: 302655

303647
type: Reaction
fast: false
reactant: 714493
notes: Abbreviation: R_PERD Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 4per + nad <==> h + nadh + ohpb Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
reversible: true
name: Erythronate 4-phosphate (4per) dehydrogenase
reactant: 714481
product: 714505
product: 714517
kinetic law: 714541
product: 714529

714493
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stoichiometry: 1.0
species: 302719

714481
type: SpeciesReference
stoichiometry: 1.0
species: 302456

714505
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stoichiometry: 1.0
species: 302659

714517
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stoichiometry: 1.0
species: 302720

305264
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value: 0.0

305262
type: LocalParameter
value: 0.0

305261
type: LocalParameter
value: 999999.0

305259
type: LocalParameter
value: -999999.0

714529
type: SpeciesReference
stoichiometry: 1.0
species: 302743

303349
type: Reaction
kinetic law: 704589
product: 704577
reactant: 704565
notes: Abbreviation: R_EX_ser_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : ser-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Serine exchange

304502
type: LocalParameter
value: 0.0

304501
type: LocalParameter
value: 0.0

304500
type: LocalParameter
value: 999999.0

304499
type: LocalParameter
value: 0.0

704577
type: SpeciesReference
stoichiometry: 1.0
species: 303063

704565
type: SpeciesReference
stoichiometry: 1.0
species: 302908

303538
type: Reaction
name: NADH dehydrogenase (demethylmenaquinone-8 & 2.8 protons)
product: 710802
reactant: 710766
reactant: 710778
product: 710827
notes: Abbreviation: R_NADH8 Synonyms: _0 EC Number: 1.6.5.3 SUBSYSTEM: Oxidative Phosphorylation Equation: _2dmmq8[c] + (3.8) h[c] + nadh[c] --> 2dmmql8[c] + (2.8) h[e] + nad[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_193#ABBREVIATION:ndh#ECNUMBERS:1.16.1.-,-!-,1.6.99.3# proteins: NAME:NADH dehydrogenase II#ABBREVIATION:Ndh# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_193)
product: 710814
reversible: false
fast: false
kinetic law: 710839
reactant: 710790

710802
type: SpeciesReference
stoichiometry: 1.0
species: 302423

710766
type: SpeciesReference
stoichiometry: 1.0
species: 302422

710778
type: SpeciesReference
stoichiometry: 3.8
species: 302659

710827
type: SpeciesReference
stoichiometry: 1.0
species: 302719

710814
type: SpeciesReference
stoichiometry: 2.8
species: 302660

304917
type: LocalParameter
value: 0.0

304916
type: LocalParameter
value: 0.0

304915
type: LocalParameter
value: 999999.0

304914
type: LocalParameter
value: 0.0

710790
type: SpeciesReference
stoichiometry: 1.0
species: 302720

303470
type: Reaction
reversible: true
product: 708395
reactant: 708371
notes: Abbreviation: R_ILETA Synonyms: _0 EC Number: 2.6.1.42 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : akg + ile-L <==> 3mop + glu-L Confidence Level: 2 genes: LOCUS:BLBBGE_455#ABBREVIATION:ilvE#ECNUMBERS:2.6.1.42,-!-,2.6.1.2# proteins: NAME:Branched-chain-amino-acid aminotransferase#ABBREVIATION:IlvE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_455)
product: 708383
kinetic law: 708407
name: isoleucine transaminase
reactant: 708359
fast: false

708395
type: SpeciesReference
stoichiometry: 1.0
species: 302633

708371
type: SpeciesReference
stoichiometry: 1.0
species: 302679

708383
type: SpeciesReference
stoichiometry: 1.0
species: 302445

304763
type: LocalParameter
value: 0.0

304762
type: LocalParameter
value: 0.0

304761
type: LocalParameter
value: 999999.0

304760
type: LocalParameter
value: -999999.0

708359
type: SpeciesReference
stoichiometry: 1.0
species: 302500

303756
type: Reaction
fast: false
product: 719376
reactant: 719315
kinetic law: 719400
reactant: 719339
product: 719364
notes: Abbreviation: R_SULabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + so4[e] --> adp[c] + h[c] + pi[c] + so4[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 719351
reactant: 719327
reversible: false
name: sulfate transport via ABC system
product: 719388

719376
type: SpeciesReference
stoichiometry: 1.0
species: 302853

719315
type: SpeciesReference
stoichiometry: 1.0
species: 302526

305628
type: LocalParameter
value: 0.0

305627
type: LocalParameter
value: 0.0

305626
type: LocalParameter
value: 999999.0

305625
type: LocalParameter
value: 0.0

719339
type: SpeciesReference
stoichiometry: 1.0
species: 302919

719364
type: SpeciesReference
stoichiometry: 1.0
species: 302659

719351
type: SpeciesReference
stoichiometry: 1.0
species: 302493

719327
type: SpeciesReference
stoichiometry: 1.0
species: 302655

719388
type: SpeciesReference
stoichiometry: 1.0
species: 302918

303361
type: Reaction
kinetic law: 704816
product: 704804
reactant: 704792
notes: Abbreviation: R_EX_tyr_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : tyr-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Tyrosine exchange

304528
type: LocalParameter
value: 0.0

304527
type: LocalParameter
value: 0.0

304526
type: LocalParameter
value: 999999.0

304525
type: LocalParameter
value: 0.0

704804
type: SpeciesReference
stoichiometry: 1.0
species: 303073

704792
type: SpeciesReference
stoichiometry: 1.0
species: 302955

303523
type: Reaction
reactant: 710287
reversible: true
reactant: 710301
notes: Abbreviation: R_MTHFD Synonyms: _0 EC Number: 1.5.1.5 SUBSYSTEM: Folate Metabolism Equation: [c] : mlthf + nadp <==> h + methf + nadph Confidence Level: 2 genes: LOCUS:BLBBGE_442#ABBREVIATION:folD#ECNUMBERS:1.5.1.5,-!-,3.5.4.9# proteins: NAME:Methylene-tetrahydrofolate dehydrogenase#ABBREVIATION:FolD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_442)
product: 710340
name: methylenetetrahydrofolate dehydrogenase (NADP)
fast: false
product: 710327
kinetic law: 710353
product: 710314

710287
type: SpeciesReference
stoichiometry: 1.0
species: 302708

710301
type: SpeciesReference
stoichiometry: 1.0
species: 302723

710340
type: SpeciesReference
stoichiometry: 1.0
species: 302724

710327
type: SpeciesReference
stoichiometry: 1.0
species: 302705

304885
type: LocalParameter
value: 0.0

304884
type: LocalParameter
value: 0.0

304883
type: LocalParameter
value: 999999.0

304882
type: LocalParameter
value: -999999.0

710314
type: SpeciesReference
stoichiometry: 1.0
species: 302659