MODEL1109150000
type: SBMLModel
reaction: COPASI81
species: 843039
rule: 845209
species: 843217
parameter: COPASI57
reaction: COPASI125
species: 843278
time units: MODEL1105180000#
parameter: 845345
reaction: COPASI153
reaction: COPASI146
parameter: COPASI53
species: 843248
reaction: COPASI121
species: COPASI23
reaction: COPASI101
species: COPASI17
species: 843271
reaction: COPASI167
reaction: COPASI107
species: COPASI12
reaction: COPASI97
rule: 845200
species: 843108
species: 843276
function def: COPASI174
parameter: COPASI48
species: COPASI10
reaction: COPASI103
species: 843033
parameter: COPASI70
reaction: COPASI127
reaction: COPASI93
species: COPASI24
species: COPASI15
parameter: COPASI69
species: 843671
initial assignment: MODEL1109150000#
parameter: COPASI44
rule: 845199
reaction: COPASI148
reaction: COPASI165
species: COPASI22
reaction: COPASI130
species: 843242
reaction: COPASI158
reaction: COPASI123
reaction: COPASI129
parameter: COPASI65
species: 843273
species: 843041
reaction: COPASI109
reaction: COPASI113
name: Rate Law for Inflow
parameter: COPASI40
reaction: COPASI151
reaction: COPASI144
name: Rate Law for Membrane binding
reaction: COPASI161
reaction: COPASI74
species: 843320
rule: 845194
parameter: COPASI61
reaction: COPASI84
reaction: COPASI105
reaction: COPASI77
species: COPASI27
species: COPASI5
reaction: COPASI139
reaction: COPASI90
parameter: COPASI46
reaction: COPASI80
rule: 845191
species: 843272
species: COPASI13
parameter: COPASI67
reaction: COPASI142
species: 843043
reaction: COPASI135

COPASI81
type: Reaction
kinetic law: 655828
product: 655816
reactant: 655804
reactant: 655792
fast: false
reversible: true
name: S: TF:VIIa binding of IX

845070
type: LocalParameter
value: 1.0
name: k2

845068
type: LocalParameter
value: 8950000.0
name: k1

655816
type: SpeciesReference
stoichiometry: 1.0
species: COPASI9

COPASI9
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z9_E7m

COPASI2
type: Compartment
constant: true
size: 1.0
spatial dimensions: 3.0
name: plasma

655804
type: SpeciesReference
stoichiometry: 1.0
species: COPASI8

COPASI8
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 9.0E-8
initial amount: NaN
in compartment: COPASI2
name: Z9

655792
type: SpeciesReference
stoichiometry: 1.0
species: 843034

843034
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: E7m

843039
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z7m_E10

843217
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: APC_E5m

COPASI57
type: Parameter
constant: true
value: 6.25E7
name: kp_flow

COPASI125
type: Reaction
kinetic law: 657899
reactant: 657887
fast: false
reversible: false
name: IR: ATIII inactivation of IXa

845164
type: LocalParameter
value: 0.1
name: k1

657887
type: SpeciesReference
stoichiometry: 1.0
species: 843108

843108
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: E9

843278
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: E9m

845345
type: Parameter
constant: true
value: 2.5E-9
name: TFPIout

COPASI153
type: Reaction
kinetic law: 658715
reactant: 658703
fast: false
reversible: false
name: MF: VII

658703
type: SpeciesReference
stoichiometry: 1.0
species: 843033

843033
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z7m

COPASI146
type: Reaction
kinetic law: 658547
reactant: 658535
fast: false
reversible: false
name: Flow: APC

658535
type: SpeciesReference
stoichiometry: 1.0
species: 843194

843194
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: APC

COPASI53
type: Parameter
constant: true
value: 1.0E-5
name: L

843248
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z5m

COPASI121
type: Reaction
kinetic law: 657742
product: 657730
reactant: 657718
reactant: 657706
fast: false
reversible: true
name: IR: APC binding of Va

845156
type: LocalParameter
value: 1.0
name: k2

845154
type: LocalParameter
value: 1.2E8
name: k1

657730
type: SpeciesReference
stoichiometry: 1.0
species: 843217

657718
type: SpeciesReference
stoichiometry: 1.0
species: 843220

843220
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: E5m

657706
type: SpeciesReference
stoichiometry: 1.0
species: 843194

COPASI23
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z2m_PRO

COPASI101
type: Reaction
kinetic law: 656789
modifier: 656777
product: 656765
reactant: 656753
fast: false
reversible: true
name: BPS: Factors IIa

845115
type: LocalParameter
value: 5.9
name: k2

845114
type: LocalParameter
value: 1.0E7
name: k1

COPASI34
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: P2

656765
type: SpeciesReference
stoichiometry: 1.0
species: COPASI16

COPASI16
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: E2m

656753
type: SpeciesReference
stoichiometry: 1.0
species: 843041

843041
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: E2

COPASI17
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: TEN

843271
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z5m_E2m

COPASI167
type: Reaction
kinetic law: 659063
product: 659051
fast: false
reversible: false
name: Inflow: IX

659051
type: SpeciesReference
stoichiometry: 1.0
species: COPASI8

COPASI107
type: Reaction
kinetic law: 657078
product: 657066
product: 657054
reactant: 657042
fast: false
reversible: false
name: RPS: Xa activation of VIII

845126
type: LocalParameter
value: 0.023
name: k1

657066
type: SpeciesReference
stoichiometry: 1.0
species: 843246

843246
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: E10m

657054
type: SpeciesReference
stoichiometry: 1.0
species: COPASI14

COPASI14
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: E8m

657042
type: SpeciesReference
stoichiometry: 1.0
species: 843273

843273
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z8m_E10m

COPASI12
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.2E-10
initial amount: NaN
in compartment: COPASI2
name: Psub

COPASI97
type: Reaction
kinetic law: 656597
modifier: 656585
product: 656573
reactant: 656561
fast: false
reversible: true
name: BPS: Factors Va

845105
type: LocalParameter
value: 0.17
name: k2

845104
type: LocalParameter
value: 5.7E7
name: k1

COPASI28
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: P5

656573
type: SpeciesReference
stoichiometry: 1.0
species: 843220

656561
type: SpeciesReference
stoichiometry: 1.0
species: COPASI30

COPASI30
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: E5

843276
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z8m_E2m

COPASI48
type: Parameter
constant: true
value: 3000.0
name: N5pl

COPASI10
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: PL

COPASI103
type: Reaction
kinetic law: 656886
product: 656874
product: 656862
reactant: 656850
fast: false
reversible: false
name: RPS: Xa activation of V

845118
type: LocalParameter
value: 0.046
name: k1

656874
type: SpeciesReference
stoichiometry: 1.0
species: 843246

656862
type: SpeciesReference
stoichiometry: 1.0
species: 843220

656850
type: SpeciesReference
stoichiometry: 1.0
species: 843250

843250
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z5m_E10m

COPASI70
type: Parameter
constant: false
value: 0.0
name: Z7_mtot

COPASI127
type: Reaction
kinetic law: 657947
reactant: 657935
fast: false
reversible: false
name: IR: ATIII inactivation of IIa

845166
type: LocalParameter
value: 0.2
name: k1

657935
type: SpeciesReference
stoichiometry: 1.0
species: 843041

COPASI93
type: Reaction
kinetic law: 656405
modifier: 656393
product: 656381
reactant: 656369
fast: false
reversible: true
name: BPS: Factors IXa*

845096
type: LocalParameter
value: 0.0
name: Z_MTOT

845095
type: LocalParameter
value: 0.025
name: k2

845094
type: LocalParameter
value: 1.0E7
name: k1

COPASI26
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: P9*

656381
type: SpeciesReference
stoichiometry: 1.0
species: COPASI18

COPASI18
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: E9m*

656369
type: SpeciesReference
stoichiometry: 1.0
species: 843108

COPASI24
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: P9

COPASI15
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.5E-9
initial amount: NaN
in compartment: COPASI2
name: TFPI

COPASI69
type: Parameter
constant: false
value: 0.0
name: E10_mtot

843671
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z7_E10

COPASI55
type: Parameter
constant: true
value: 2.03581321244618E-5
name: hbar

COPASI5
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.0E-8
initial amount: NaN
in compartment: COPASI2
name: Z7

COPASI6
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.0E-10
initial amount: NaN
in compartment: COPASI2
name: E7

COPASI32
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.0E-9
initial amount: NaN
in compartment: COPASI2
name: Z8

COPASI35
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.4E-6
initial amount: NaN
in compartment: COPASI2
name: Z2

COPASI38
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 7.36806299728077E-12
initial amount: NaN
in compartment: COPASI4
name: TF

COPASI4
type: Compartment
constant: true
size: 1.0
spatial dimensions: 3.0
name: subendothelium

COPASI29
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.0E-8
initial amount: NaN
in compartment: COPASI2
name: Z5

COPASI7
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.7E-7
initial amount: NaN
in compartment: COPASI2
name: Z10

COPASI56
type: Parameter
constant: true
value: 508.953303111545
name: kc_flow

COPASI44
type: Parameter
constant: true
value: 9.0E-8
name: Z9out

COPASI148
type: Reaction
kinetic law: 658595
reactant: 658583
fast: false
reversible: false
name: Flow: VII:IIa complex

658583
type: SpeciesReference
stoichiometry: 1.0
species: COPASI36

COPASI36
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z7_E2

COPASI165
type: Reaction
kinetic law: 659015
product: 659003
fast: false
reversible: false
name: Inflow: VIIa

659003
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

COPASI22
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z10m_TEN*

COPASI130
type: Reaction
kinetic law: 658091
product: 658079
reactant: 658067
reactant: 658055
fast: false
reversible: false
name: PR: Platelet activation by platelet in solution

845172
type: LocalParameter
value: 3.0E8
name: k1

658079
type: SpeciesReference
stoichiometry: 2.0
species: COPASI13

COPASI13
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: PLav

658067
type: SpeciesReference
stoichiometry: 1.0
species: COPASI13

658055
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

843242
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: TFPI_E10

COPASI158
type: Reaction
kinetic law: 658835
reactant: 658823
fast: false
reversible: false
name: MF: X:VIIa complex

658823
type: SpeciesReference
stoichiometry: 1.0
species: 843065

843065
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z10_E7m

COPASI123
type: Reaction
kinetic law: 657826
product: 657814
reactant: 657802
reactant: 657790
fast: false
reversible: true
name: IR: TFPI binding with Xa

845160
type: LocalParameter
value: 3.3E-4
name: k2

845158
type: LocalParameter
value: 1.6E7
name: k1

657814
type: SpeciesReference
stoichiometry: 1.0
species: 843242

657802
type: SpeciesReference
stoichiometry: 1.0
species: 843037

843037
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: E10

657790
type: SpeciesReference
stoichiometry: 1.0
species: COPASI15

COPASI129
type: Reaction
kinetic law: 658043
product: 658031
reactant: 658019
reactant: 658007
fast: false
reversible: true
name: PR: Activated platelet binding to SE

845170
type: LocalParameter
value: 0.0
name: k2

845169
type: LocalParameter
value: 2.0E10
name: k1

658031
type: SpeciesReference
stoichiometry: 1.0
species: COPASI11

COPASI11
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: PLas

658019
type: SpeciesReference
stoichiometry: 1.0
species: COPASI12

658007
type: SpeciesReference
stoichiometry: 1.0
species: COPASI13

COPASI65
type: Parameter
constant: false
value: 0.0
name: Z9_mtot

COPASI109
type: Reaction
kinetic law: 657175
product: 657163
product: 657151
reactant: 657139
fast: false
reversible: false
name: RPS: IIa activation of VIII

845130
type: LocalParameter
value: 0.9
name: k1

657163
type: SpeciesReference
stoichiometry: 1.0
species: COPASI16

657151
type: SpeciesReference
stoichiometry: 1.0
species: COPASI14

657139
type: SpeciesReference
stoichiometry: 1.0
species: 843276

COPASI113
type: Reaction
kinetic law: 657368
product: 657356
reactant: 657344
reactant: 657332
fast: false
reversible: true
name: RPS: VIIIa:IXa binding of X

845140
type: LocalParameter
value: 1.0
name: k2

845139
type: LocalParameter
value: 1.31E8
name: k1

657356
type: SpeciesReference
stoichiometry: 1.0
species: COPASI20

COPASI20
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z10m_TEN

657344
type: SpeciesReference
stoichiometry: 1.0
species: COPASI17

657332
type: SpeciesReference
stoichiometry: 1.0
species: COPASI19

COPASI19
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z10m

COPASI40
type: Parameter
constant: true
value: 1.0E-8
name: Z5out

COPASI151
type: Reaction
kinetic law: 658667
reactant: 658655
fast: false
reversible: false
name: Flow: PL

658655
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

COPASI144
type: Reaction
kinetic law: 658499
reactant: 658487
fast: false
reversible: false
name: Flow: Xa

658487
type: SpeciesReference
stoichiometry: 1.0
species: 843037

COPASI161
type: Reaction
kinetic law: 658919
modifier: 658907
product: 658895
fast: false
reversible: false
name: MF: V release

658895
type: SpeciesReference
stoichiometry: 1.0
species: COPASI29

COPASI74
type: Reaction
kinetic law: 655489
modifier: 655477
product: 655465
reactant: 655453
fast: false
reversible: true
name: S: VIIa binding with TF

845056
type: LocalParameter
value: 0.005
name: k2

845055
type: LocalParameter
value: 5.0E7
name: k1

655465
type: SpeciesReference
stoichiometry: 1.0
species: 843034

655453
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

843320
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: PRO

COPASI61
type: Parameter
constant: false
value: 0.0
name: Z5_mtot

COPASI84
type: Reaction
kinetic law: 655973
product: 655960
product: 655948
reactant: 655936
fast: false
reversible: false
name: P: Xa activation of VII

845075
type: LocalParameter
value: 5.0
name: k1

655960
type: SpeciesReference
stoichiometry: 1.0
species: 843037

655948
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

655936
type: SpeciesReference
stoichiometry: 1.0
species: 843671

COPASI105
type: Reaction
kinetic law: 656982
product: 656970
product: 656958
reactant: 656946
fast: false
reversible: false
name: RPS: IIa activation of V

845122
type: LocalParameter
value: 0.23
name: k1

656970
type: SpeciesReference
stoichiometry: 1.0
species: COPASI16

656958
type: SpeciesReference
stoichiometry: 1.0
species: 843220

656946
type: SpeciesReference
stoichiometry: 1.0
species: 843271

COPASI77
type: Reaction
kinetic law: 655634
product: 655622
reactant: 655610
reactant: 655597
fast: false
reversible: true
name: S: IIa binding of TF:VII

845062
type: LocalParameter
value: 1.0
name: k2

845060
type: LocalParameter
value: 392000.0
name: k1

655622
type: SpeciesReference
stoichiometry: 1.0
species: 843043

843043
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z7m_E2

655610
type: SpeciesReference
stoichiometry: 1.0
species: 843033

655597
type: SpeciesReference
stoichiometry: 1.0
species: 843041

COPASI27
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: P10

COPASI139
type: Reaction
kinetic law: 658379
reactant: 658367
fast: false
reversible: false
name: Flow: VIII

658367
type: SpeciesReference
stoichiometry: 1.0
species: COPASI32

COPASI90
type: Reaction
kinetic law: 656261
product: 656249
product: 656237
reactant: 656225
fast: false
reversible: false
name: P: IIa activation of VIII

845087
type: LocalParameter
value: 0.9
name: k1

656249
type: SpeciesReference
stoichiometry: 1.0
species: 843041

656237
type: SpeciesReference
stoichiometry: 1.0
species: COPASI33

COPASI33
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: E8

656225
type: SpeciesReference
stoichiometry: 1.0
species: COPASI37

COPASI37
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z8_E2

COPASI46
type: Parameter
constant: true
value: 250000.0
name: PLout

COPASI80
type: Reaction
kinetic law: 655780
product: 655767
product: 655754
reactant: 655742
fast: false
reversible: false
name: S: TF:VIIa activation of X

845067
type: LocalParameter
value: 1.15
name: k1

655767
type: SpeciesReference
stoichiometry: 1.0
species: 843034

655754
type: SpeciesReference
stoichiometry: 1.0
species: 843037

655742
type: SpeciesReference
stoichiometry: 1.0
species: 843065

843272
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z8m

COPASI67
type: Parameter
constant: false
value: 0.0
name: E9*_mtot

COPASI142
type: Reaction
kinetic law: 658451
reactant: 658439
fast: false
reversible: false
name: Flow: IXa

658439
type: SpeciesReference
stoichiometry: 1.0
species: 843108

COPASI135
type: Reaction
kinetic law: 658283
reactant: 658271
fast: false
reversible: false
name: Flow: V

658271
type: SpeciesReference
stoichiometry: 1.0
species: COPASI29

COPASI115
type: Reaction
kinetic law: 657465
product: 657453
reactant: 657441
reactant: 657429
fast: false
reversible: true
name: RPS: VIIIa:IXa* binding of X

845144
type: LocalParameter
value: 1.0
name: k2

845142
type: LocalParameter
value: 1.31E8
name: k1

657453
type: SpeciesReference
stoichiometry: 1.0
species: COPASI22

657441
type: SpeciesReference
stoichiometry: 1.0
species: COPASI21

COPASI21
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: TEN*

657429
type: SpeciesReference
stoichiometry: 1.0
species: COPASI19

COPASI42
type: Parameter
constant: true
value: 1.0E-10
name: E7out

COPASI163
type: Reaction
kinetic law: 658967
product: 658955
fast: false
reversible: false
name: Inflow: V

658955
type: SpeciesReference
stoichiometry: 1.0
species: COPASI29

COPASI156
type: Reaction
kinetic law: 658787
reactant: 658775
fast: false
reversible: false
name: MF: VII:Xa complex

658775
type: SpeciesReference
stoichiometry: 1.0
species: 843039

COPASI63
type: Parameter
constant: false
value: 0.0
name: Z8_mtot

COPASI86
type: Reaction
kinetic law: 656069
product: 656057
product: 656045
reactant: 656033
fast: false
reversible: false
name: P: IIa activation of VII

845079
type: LocalParameter
value: 0.061
name: k1

656057
type: SpeciesReference
stoichiometry: 1.0
species: 843041

656045
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

656033
type: SpeciesReference
stoichiometry: 1.0
species: COPASI36

COPASI131
type: Reaction
kinetic law: 658151
product: 658139
product: 658127
reactant: 658115
reactant: 658103
fast: false
reversible: false
name: PR: Platelet activation by platelet on SE

845173
type: LocalParameter
value: 3.0E8
name: k1

658139
type: SpeciesReference
stoichiometry: 1.0
species: COPASI11

658127
type: SpeciesReference
stoichiometry: 1.0
species: COPASI13

658115
type: SpeciesReference
stoichiometry: 1.0
species: COPASI11

658103
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

COPASI79
type: Reaction
kinetic law: 655730
product: 655718
reactant: 655706
reactant: 655694
fast: false
reversible: true
name: S: TF:VIIa binding of X

845066
type: LocalParameter
value: 1.0
name: k2

845064
type: LocalParameter
value: 8950000.0
name: k1

655718
type: SpeciesReference
stoichiometry: 1.0
species: 843065

655706
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

655694
type: SpeciesReference
stoichiometry: 1.0
species: 843034

COPASI111
type: Reaction
kinetic law: 657271
product: 657259
reactant: 657247
reactant: 657235
fast: false
reversible: true
name: RPS: VIIIa binding with IXa*

845135
type: LocalParameter
value: 0.01
name: k2

845134
type: LocalParameter
value: 1.0E8
name: k1

657259
type: SpeciesReference
stoichiometry: 1.0
species: COPASI21

657247
type: SpeciesReference
stoichiometry: 1.0
species: COPASI18

657235
type: SpeciesReference
stoichiometry: 1.0
species: COPASI14

COPASI117
type: Reaction
kinetic law: 657562
product: 657550
reactant: 657538
reactant: 657526
fast: false
reversible: true
name: RPS: Va:Xa binding of II

845148
type: LocalParameter
value: 1.0
name: k2

845146
type: LocalParameter
value: 1.03E8
name: k1

657550
type: SpeciesReference
stoichiometry: 1.0
species: COPASI23

657538
type: SpeciesReference
stoichiometry: 1.0
species: 843320

657526
type: SpeciesReference
stoichiometry: 1.0
species: 843405

843405
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z2m

W3 CDTF: Thu Sep 15 14:30:54 BST 2011

COPASI82
type: Reaction
kinetic law: 655876
product: 655864
product: 655852
reactant: 655840
fast: false
reversible: false
name: S: TF:VIIa activation of IX

845071
type: LocalParameter
value: 1.15
name: k1

655864
type: SpeciesReference
stoichiometry: 1.0
species: 843034

655852
type: SpeciesReference
stoichiometry: 1.0
species: 843108

655840
type: SpeciesReference
stoichiometry: 1.0
species: COPASI9

COPASI58
type: Parameter
constant: true
value: 500.0
name: shear_rate

COPASI137
type: Reaction
kinetic law: 658331
reactant: 658319
fast: false
reversible: false
name: Flow: VII

658319
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

COPASI154
type: Reaction
kinetic law: 658739
reactant: 658727
fast: false
reversible: false
name: MF: VIIa

658727
type: SpeciesReference
stoichiometry: 1.0
species: 843034

COPASI147
type: Reaction
kinetic law: 658571
reactant: 658559
fast: false
reversible: false
name: Flow: V:IIa complex

658559
type: SpeciesReference
stoichiometry: 1.0
species: 843692

843692
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z5_E2

COPASI54
type: Parameter
constant: true
value: 5.0E-7
name: D

COPASI102
type: Reaction
kinetic law: 656838
product: 656826
reactant: 656813
reactant: 656801
fast: false
reversible: true
name: RPS: Xa binding of V

845117
type: LocalParameter
value: 1.0
name: k2

845116
type: LocalParameter
value: 1.0E8
name: k1

656826
type: SpeciesReference
stoichiometry: 1.0
species: 843250

656813
type: SpeciesReference
stoichiometry: 1.0
species: 843246

656801
type: SpeciesReference
stoichiometry: 1.0
species: 843248

COPASI140
type: Reaction
kinetic law: 658403
reactant: 658391
fast: false
reversible: false
name: Flow: VIIIa

658391
type: SpeciesReference
stoichiometry: 1.0
species: COPASI33

COPASI168
type: Reaction
kinetic law: 659087
product: 659075
fast: false
reversible: false
name: Inflow: X

659075
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

COPASI133
type: Reaction
kinetic law: 658235
reactant: 658223
fast: false
reversible: false
name: Flow: II

658223
type: SpeciesReference
stoichiometry: 1.0
species: COPASI35

W3 CDTF: Thu Sep 15 14:31:35 BST 2011

COPASI150
type: Reaction
kinetic law: 658643
reactant: 658631
fast: false
reversible: false
name: Flow: VIII:IIa complex

658631
type: SpeciesReference
stoichiometry: 1.0
species: COPASI37

COPASI119
type: Reaction
kinetic law: 657658
product: 657646
reactant: 657634
reactant: 657622
fast: false
reversible: true
name: IR: APC binding of VIIIa

845152
type: LocalParameter
value: 1.0
name: k2

845150
type: LocalParameter
value: 1.2E8
name: k1

657646
type: SpeciesReference
stoichiometry: 1.0
species: 843195

843195
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: APC_E8m

657634
type: SpeciesReference
stoichiometry: 1.0
species: COPASI14

657622
type: SpeciesReference
stoichiometry: 1.0
species: 843194

COPASI98
type: Reaction
kinetic law: 656645
modifier: 656633
product: 656621
reactant: 656609
fast: false
reversible: true
name: BPS: Factors VIII

845108
type: LocalParameter
value: 0.17
name: k2

845107
type: LocalParameter
value: 5.0E7
name: k1

COPASI31
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: P8

656621
type: SpeciesReference
stoichiometry: 1.0
species: 843272

656609
type: SpeciesReference
stoichiometry: 1.0
species: COPASI32

COPASI143
type: Reaction
kinetic law: 658475
reactant: 658463
fast: false
reversible: false
name: Flow: X

658463
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

COPASI50
type: Parameter
constant: true
value: 250.0
name: N9pl

COPASI73
type: Reaction
kinetic law: 655441
modifier: 655428
product: 655416
reactant: 655404
fast: false
reversible: true
name: S: VII binding with TF

845053
type: LocalParameter
value: 0.005
name: k2

845052
type: LocalParameter
value: 5.0E7
name: k1

655416
type: SpeciesReference
stoichiometry: 1.0
species: 843033

655404
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

COPASI71
type: Parameter
constant: false
value: 0.0
name: E7_mtot

COPASI94
type: Reaction
kinetic law: 656453
modifier: 656441
product: 656429
reactant: 656417
fast: false
reversible: true
name: BPS: Factors X

845098
type: LocalParameter
value: 0.025
name: k2

845097
type: LocalParameter
value: 1.0E7
name: k1

656429
type: SpeciesReference
stoichiometry: 1.0
species: COPASI19

656417
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

COPASI149
type: Reaction
kinetic law: 658619
reactant: 658607
fast: false
reversible: false
name: Flow: VII:X complex

658607
type: SpeciesReference
stoichiometry: 1.0
species: 843671

COPASI124
type: Reaction
kinetic law: 657875
product: 657863
reactant: 657851
reactant: 657838
fast: false
reversible: true
name: IR: TFPI:Xa binding with TF:VIIa

845162
type: LocalParameter
value: 0.0011
name: k2

845161
type: LocalParameter
value: 1.0E7
name: k1

657863
type: SpeciesReference
stoichiometry: 1.0
species: 843244

843244
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: TFPI_E10_E7m

657851
type: SpeciesReference
stoichiometry: 1.0
species: 843034

657838
type: SpeciesReference
stoichiometry: 1.0
species: 843242

COPASI66
type: Parameter
constant: false
value: 0.0
name: E9_mtot

COPASI114
type: Reaction
kinetic law: 657417
product: 657404
product: 657392
reactant: 657380
fast: false
reversible: false
name: RPS: VIIIa:IXa activation of X

845141
type: LocalParameter
value: 20.0
name: k1

657404
type: SpeciesReference
stoichiometry: 1.0
species: COPASI17

657392
type: SpeciesReference
stoichiometry: 1.0
species: 843246

657380
type: SpeciesReference
stoichiometry: 1.0
species: COPASI20

COPASI152
type: Reaction
kinetic law: 658691
reactant: 658679
fast: false
reversible: false
name: Flow: TFPI:Xa complex

658679
type: SpeciesReference
stoichiometry: 1.0
species: 843242

COPASI145
type: Reaction
kinetic law: 658523
reactant: 658511
fast: false
reversible: false
name: Flow: TFPI

658511
type: SpeciesReference
stoichiometry: 1.0
species: COPASI15

COPASI52
type: Parameter
constant: true
value: 2700.0
name: N10pl

COPASI75
type: Reaction
kinetic law: 655537
product: 655525
reactant: 655513
reactant: 655501
fast: false
reversible: true
name: S: Xa binding of TF:VII

845058
type: LocalParameter
value: 1.0
name: k2

845057
type: LocalParameter
value: 5000000.0
name: k1

655525
type: SpeciesReference
stoichiometry: 1.0
species: 843039

655513
type: SpeciesReference
stoichiometry: 1.0
species: 843033

655501
type: SpeciesReference
stoichiometry: 1.0
species: 843037

COPASI120
type: Reaction
kinetic law: 657694
product: 657682
reactant: 657670
fast: false
reversible: false
name: IR: APC inactivation of VIIIa

845153
type: LocalParameter
value: 0.5
name: k1

657682
type: SpeciesReference
stoichiometry: 1.0
species: 843194

657670
type: SpeciesReference
stoichiometry: 1.0
species: 843195

COPASI100
type: Reaction
kinetic law: 656741
modifier: 656729
product: 656717
reactant: 656705
fast: false
reversible: true
name: BPS: Factors II

845112
type: LocalParameter
value: 5.9
name: k2

845111
type: LocalParameter
value: 1.0E7
name: k1

656717
type: SpeciesReference
stoichiometry: 1.0
species: 843405

656705
type: SpeciesReference
stoichiometry: 1.0
species: COPASI35

COPASI62
type: Parameter
constant: false
value: 0.0
name: E5_mtot

COPASI106
type: Reaction
kinetic law: 657030
product: 657018
reactant: 657006
reactant: 656994
fast: false
reversible: true
name: RPS: Xa binding of VIII

845125
type: LocalParameter
value: 1.0
name: k2

845123
type: LocalParameter
value: 5.1E7
name: k1

657018
type: SpeciesReference
stoichiometry: 1.0
species: 843273

657006
type: SpeciesReference
stoichiometry: 1.0
species: 843246

656994
type: SpeciesReference
stoichiometry: 1.0
species: 843272

COPASI110
type: Reaction
kinetic law: 657223
product: 657211
reactant: 657199
reactant: 657187
fast: false
reversible: true
name: RPS: VIIIa binding with IXa

845133
type: LocalParameter
value: 0.01
name: k2

845131
type: LocalParameter
value: 1.0E8
name: k1

657211
type: SpeciesReference
stoichiometry: 1.0
species: COPASI17

657199
type: SpeciesReference
stoichiometry: 1.0
species: 843278

657187
type: SpeciesReference
stoichiometry: 1.0
species: COPASI14

COPASI96
type: Reaction
kinetic law: 656549
modifier: 656537
product: 656525
reactant: 656513
fast: false
reversible: true
name: BPS: Factors V

845103
type: LocalParameter
value: 0.17
name: k2

845102
type: LocalParameter
value: 5.7E7
name: k1

656525
type: SpeciesReference
stoichiometry: 1.0
species: 843248

656513
type: SpeciesReference
stoichiometry: 1.0
species: COPASI29

COPASI89
type: Reaction
kinetic law: 656213
product: 656201
reactant: 656189
reactant: 656177
fast: false
reversible: true
name: P: IIa binding of VIII

845086
type: LocalParameter
value: 1.0
name: k2

845084
type: LocalParameter
value: 2.64E7
name: k1

656201
type: SpeciesReference
stoichiometry: 1.0
species: COPASI37

656189
type: SpeciesReference
stoichiometry: 1.0
species: 843041

656177
type: SpeciesReference
stoichiometry: 1.0
species: COPASI32

COPASI91
type: Reaction
kinetic law: 656309
modifier: 656297
product: 656285
reactant: 656273
fast: false
reversible: true
name: BPS: Factors IX

845090
type: LocalParameter
value: 0.025
name: k2

845088
type: LocalParameter
value: 1.0E7
name: k1

656285
type: SpeciesReference
stoichiometry: 1.0
species: COPASI25

COPASI25
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Z9m

656273
type: SpeciesReference
stoichiometry: 1.0
species: COPASI8

COPASI47
type: Parameter
constant: true
value: 2000.0
name: N2pl

COPASI126
type: Reaction
kinetic law: 657923
reactant: 657911
fast: false
reversible: false
name: IR: ATIII inactivation of Xa

845165
type: LocalParameter
value: 0.1
name: k1

657911
type: SpeciesReference
stoichiometry: 1.0
species: 843037

COPASI92
type: Reaction
kinetic law: 656357
modifier: 656345
product: 656333
reactant: 656321
fast: false
reversible: true
name: BPS: Factors IXa

845092
type: LocalParameter
value: 0.025
name: k2

845091
type: LocalParameter
value: 1.0E7
name: k1

656333
type: SpeciesReference
stoichiometry: 1.0
species: 843278

656321
type: SpeciesReference
stoichiometry: 1.0
species: 843108

W3 CDTF: Thu Sep 15 14:31:35 BST 2011

COPASI68
type: Parameter
constant: false
value: 0.0
name: Z10_mtot

COPASI136
type: Reaction
kinetic law: 658307
reactant: 658295
fast: false
reversible: false
name: Flow: Va

658295
type: SpeciesReference
stoichiometry: 1.0
species: COPASI30

COPASI43
type: Parameter
constant: true
value: 1.0E-9
name: Z8out

COPASI164
type: Reaction
kinetic law: 658991
product: 658979
fast: false
reversible: false
name: Inflow: VII

658979
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

COPASI157
type: Reaction
kinetic law: 658811
reactant: 658799
fast: false
reversible: false
name: MF: IX:VIIa complex

658799
type: SpeciesReference
stoichiometry: 1.0
species: COPASI9

COPASI122
type: Reaction
kinetic law: 657778
product: 657766
reactant: 657754
fast: false
reversible: false
name: IR: APC inactivation of Va

845157
type: LocalParameter
value: 0.5
name: k1

657766
type: SpeciesReference
stoichiometry: 1.0
species: 843194

657754
type: SpeciesReference
stoichiometry: 1.0
species: 843217

COPASI128
type: Reaction
kinetic law: 657995
product: 657983
reactant: 657971
reactant: 657959
fast: false
reversible: true
name: PR: Unactivated platelet binding to SE

845168
type: LocalParameter
value: 0.0
name: k2

845167
type: LocalParameter
value: 2.0E10
name: k1

657983
type: SpeciesReference
stoichiometry: 1.0
species: COPASI11

657971
type: SpeciesReference
stoichiometry: 1.0
species: COPASI12

657959
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

COPASI64
type: Parameter
constant: false
value: 0.0
name: E8_mtot

COPASI108
type: Reaction
kinetic law: 657127
product: 657115
reactant: 657103
reactant: 657090
fast: false
reversible: true
name: RPS: IIa binding of VIII

845129
type: LocalParameter
value: 1.0
name: k2

845127
type: LocalParameter
value: 2.64E7
name: k1

657115
type: SpeciesReference
stoichiometry: 1.0
species: 843276

657103
type: SpeciesReference
stoichiometry: 1.0
species: COPASI16

657090
type: SpeciesReference
stoichiometry: 1.0
species: 843272

COPASI87
type: Reaction
kinetic law: 656117
product: 656105
reactant: 656093
reactant: 656081
fast: false
reversible: true
name: P: IIa binding of V

845082
type: LocalParameter
value: 1.0
name: k2

845080
type: LocalParameter
value: 1.73E7
name: k1

656105
type: SpeciesReference
stoichiometry: 1.0
species: 843692

656093
type: SpeciesReference
stoichiometry: 1.0
species: 843041

656081
type: SpeciesReference
stoichiometry: 1.0
species: COPASI29

COPASI132
type: Reaction
kinetic law: 658211
product: 658199
product: 658187
reactant: 658175
reactant: 658163
fast: false
reversible: false
name: PR: Platelet activation by thrombin

845174
type: LocalParameter
value: 0.5
name: kc2_act_times_Ae2

658199
type: SpeciesReference
stoichiometry: 1.0
species: 843041

658187
type: SpeciesReference
stoichiometry: 1.0
species: COPASI13

658175
type: SpeciesReference
stoichiometry: 1.0
species: 843041

658163
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

COPASI3
type: Compartment
constant: true
size: 1.0
spatial dimensions: 3.0
name: platelet_surface

COPASI112
type: Reaction
kinetic law: 657320
product: 657308
reactant: 657296
reactant: 657283
fast: false
reversible: true
name: RPS: Va binding with Xa

845138
type: LocalParameter
value: 0.01
name: k2

845137
type: LocalParameter
value: 1.0E8
name: k1

657308
type: SpeciesReference
stoichiometry: 1.0
species: 843320

657296
type: SpeciesReference
stoichiometry: 1.0
species: 843246

657283
type: SpeciesReference
stoichiometry: 1.0
species: 843220

COPASI170
type: Reaction
kinetic law: 659135
product: 659123
fast: false
reversible: false
name: Inflow: PL

659123
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

COPASI118
type: Reaction
kinetic law: 657610
product: 657598
product: 657586
reactant: 657574
fast: false
reversible: false
name: RPS: Va:Xa activation of II

845149
type: LocalParameter
value: 30.0
name: k1

657598
type: SpeciesReference
stoichiometry: 1.0
species: 843320

657586
type: SpeciesReference
stoichiometry: 1.0
species: COPASI16

657574
type: SpeciesReference
stoichiometry: 1.0
species: COPASI23

COPASI160
type: Reaction
kinetic law: 658883
reactant: 658871
fast: false
reversible: false
name: MF: TF

658871
type: SpeciesReference
stoichiometry: 1.0
species: COPASI38

ORG:
  orgname: EBI
n:
  given: Michael
  family: Schubert

COPASI49
type: Parameter
constant: true
value: 450.0
name: N8pl

COPASI60
type: Parameter
constant: false
value: 0.0
name: E2_mtot

COPASI83
type: Reaction
kinetic law: 655924
product: 655912
reactant: 655900
reactant: 655888
fast: false
reversible: true
name: P: Xa binding of VII

845074
type: LocalParameter
value: 1.0
name: k2

845072
type: LocalParameter
value: 5000000.0
name: k1

655912
type: SpeciesReference
stoichiometry: 1.0
species: 843671

655900
type: SpeciesReference
stoichiometry: 1.0
species: 843037

655888
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

COPASI104
type: Reaction
kinetic law: 656934
product: 656922
reactant: 656910
reactant: 656898
fast: false
reversible: true
name: RPS: IIa binding of V

845121
type: LocalParameter
value: 1.0
name: k2

845119
type: LocalParameter
value: 1.73E7
name: k1

656922
type: SpeciesReference
stoichiometry: 1.0
species: 843271

656910
type: SpeciesReference
stoichiometry: 1.0
species: COPASI16

656898
type: SpeciesReference
stoichiometry: 1.0
species: 843248

COPASI76
type: Reaction
kinetic law: 655585
product: 655573
product: 655561
reactant: 655549
fast: false
reversible: false
name: S: Xa activation of TF:VII

845059
type: LocalParameter
value: 5.0
name: k1

655573
type: SpeciesReference
stoichiometry: 1.0
species: 843037

655561
type: SpeciesReference
stoichiometry: 1.0
species: 843034

655549
type: SpeciesReference
stoichiometry: 1.0
species: 843039

COPASI59
type: Parameter
constant: false
value: 0.0
name: Z2_mtot

COPASI138
type: Reaction
kinetic law: 658355
reactant: 658343
fast: false
reversible: false
name: Flow: VIIa

658343
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

ORG:
  orgname: EBI
n:
  given: Michael
  family: Schubert

COPASI45
type: Parameter
constant: true
value: 1.7E-7
name: Z10out

COPASI166
type: Reaction
kinetic law: 659039
product: 659027
fast: false
reversible: false
name: Inflow: VIII

659027
type: SpeciesReference
stoichiometry: 1.0
species: COPASI32

COPASI159
type: Reaction
kinetic law: 658859
reactant: 658847
fast: false
reversible: false
name: MF: TFPI:Xa:VIIa complex

658847
type: SpeciesReference
stoichiometry: 1.0
species: 843244

COPASI141
type: Reaction
kinetic law: 658427
reactant: 658415
fast: false
reversible: false
name: Flow: IX

658415
type: SpeciesReference
stoichiometry: 1.0
species: COPASI8

COPASI169
type: Reaction
kinetic law: 659111
product: 659099
fast: false
reversible: false
name: Inflow: TFPI

659099
type: SpeciesReference
stoichiometry: 1.0
species: COPASI15

COPASI134
type: Reaction
kinetic law: 658259
reactant: 658247
fast: false
reversible: false
name: Flow: IIa

658247
type: SpeciesReference
stoichiometry: 1.0
species: 843041

COPASI39
type: Parameter
constant: true
value: 1.4E-6
name: Z2out

COPASI41
type: Parameter
constant: true
value: 1.0E-8
name: Z7out

COPASI99
type: Reaction
kinetic law: 656693
modifier: 656681
product: 656669
reactant: 656657
fast: false
reversible: true
name: BPS: Factors VIIIa

845110
type: LocalParameter
value: 0.17
name: k2

845109
type: LocalParameter
value: 5.0E7
name: k1

656669
type: SpeciesReference
stoichiometry: 1.0
species: COPASI14

656657
type: SpeciesReference
stoichiometry: 1.0
species: COPASI33

COPASI162
type: Reaction
kinetic law: 658943
product: 658931
fast: false
reversible: false
name: Inflow: II

658931
type: SpeciesReference
stoichiometry: 1.0
species: COPASI35

COPASI51
type: Parameter
constant: true
value: 250.0
name: N9pl*

COPASI155
type: Reaction
kinetic law: 658763
reactant: 658751
fast: false
reversible: false
name: MF: VII:IIa complex

658751
type: SpeciesReference
stoichiometry: 1.0
species: 843043

COPASI85
type: Reaction
kinetic law: 656021
product: 656009
reactant: 655997
reactant: 655985
fast: false
reversible: true
name: P: IIa binding of VII

845078
type: LocalParameter
value: 1.0
name: k2

845076
type: LocalParameter
value: 392000.0
name: k1

656009
type: SpeciesReference
stoichiometry: 1.0
species: COPASI36

655997
type: SpeciesReference
stoichiometry: 1.0
species: 843041

655985
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

COPASI78
type: Reaction
kinetic law: 655682
product: 655670
product: 655658
reactant: 655646
fast: false
reversible: false
name: S: IIa activation of TF:VII

845063
type: LocalParameter
value: 0.061
name: k1

655670
type: SpeciesReference
stoichiometry: 1.0
species: 843041

655658
type: SpeciesReference
stoichiometry: 1.0
species: 843034

655646
type: SpeciesReference
stoichiometry: 1.0
species: 843043

COPASI72
type: Parameter
constant: true
value: 0.0
name: p_prime/(1-p)

COPASI116
type: Reaction
kinetic law: 657514
product: 657502
product: 657489
reactant: 657477
fast: false
reversible: false
name: RPS: VIIIa:IXa* activation of X

845145
type: LocalParameter
value: 20.0
name: k1

657502
type: SpeciesReference
stoichiometry: 1.0
species: COPASI21

657489
type: SpeciesReference
stoichiometry: 1.0
species: 843246

657477
type: SpeciesReference
stoichiometry: 1.0
species: COPASI22

COPASI95
type: Reaction
kinetic law: 656501
modifier: 656489
product: 656477
reactant: 656465
fast: false
reversible: true
name: BPS: Factors Xa

845101
type: LocalParameter
value: 0.025
name: k2

845100
type: LocalParameter
value: 1.0E7
name: k1

656477
type: SpeciesReference
stoichiometry: 1.0
species: 843246

656465
type: SpeciesReference
stoichiometry: 1.0
species: 843037

COPASI88
type: Reaction
kinetic law: 656165
product: 656153
product: 656141
reactant: 656129
fast: false
reversible: false
name: P: IIa activation of V

845083
type: LocalParameter
value: 0.23
name: k1

656153
type: SpeciesReference
stoichiometry: 1.0
species: 843041

656141
type: SpeciesReference
stoichiometry: 1.0
species: COPASI30

656129
type: SpeciesReference
stoichiometry: 1.0
species: 843692

ORG:
  orgname: EBI
n:
  given: Michael
  family: Schubert

W3 CDTF: Thu Sep 15 14:31:35 BST 2011