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species: 286768
species: 283758
reaction: 288992
reaction: 290308
reaction: 287818
species: 286156
species: 285844
reaction: 289309
species: 283587
reaction: 290274
reaction: 289872
reaction: 288427
species: 285511
reaction: 288983
reaction: 288376
reaction: 289275
reaction: 290226
species: 284454
reaction: 287935
species: 285919
reaction: 289990
reaction: 290574
species: 286741
reaction: 287455
species: 283530
reaction: 288911
species: 285168
species: 286819
reaction: 289313
species: 285318
species: 284753
reaction: 288319
reaction: 289447
reaction: 287785
reaction: 289217
species: 284472
species: 283701
species: 284397
species: 285892
species: 284271
reaction: 287361
species: 284388
reaction: 290482
reaction: 287713
reaction: 287346
species: 283302
reaction: 287848
species: 286474
reaction: 288458
reaction: 289628
species: 286090
reaction: 288584
reaction: 290816
species: 286888
reaction: 290830
species: 282950
species: 284824
species: 286726
species: 285074
species: 284687
species: 283755
reaction: 287965
reaction: 290256
reaction: 288575
reaction: 289029
reaction: 288941
reaction: 289632
species: 285718
species: 284337
reaction: 289822
reaction: 289233
reaction: 287917
species: 285757
reaction: 290406
species: 285165
reaction: 290518
reaction: 288503
reaction: 290532
reaction: 288638

286768
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constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Glutamine_C5H10N2O3

282870
type: Compartment
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size: NaN
spatial dimensions: 3.0

283758
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Arabinose_C5H10O5

288992
type: Reaction
fast: false
reversible: true
product: 380654
product: 380667
reactant: 380642
notes: GENE_ASSOCIATION: ( YKL182W and YPL231W ) PROTEIN_ASSOCIATION: Fas SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 3.1.2.14
product: 380679
kinetic law: 380692
reactant: 380630
name: R_fatty_acyl_ACP_hydrolase

380654
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species: 283416

283416
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_acyl_carrier_protein_C11H21N2O7PRS

282871
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

380667
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stoichiometry: 1.0
species: 284787

284787
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: M_H_H

380642
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stoichiometry: 1.0
species: 286156

286156
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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380679
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species: 286411

286411
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_tetradecenoate__n_C141__C14H25O2

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380630
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stoichiometry: 1.0
species: 284757

284757
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_H2O_H2O

290308
type: Reaction
reactant: 425400
kinetic law: 425448
product: 425424
reversible: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 4.1.1.36
name: R_phosphopantothenoylcysteine_decarboxylase
fast: false
product: 425436
reactant: 425412

425400
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stoichiometry: 1.0
species: 283353

283353
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N___R__4_Phosphopantothenoyl__L_cysteine_C12H20N2O9PS

302130
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value: 0.0

302128
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302127
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302125
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value: 999999.0

302124
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value: 0.0

425424
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stoichiometry: 1.0
species: 283992

283992
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_CO2_CO2

425436
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stoichiometry: 1.0
species: 285640

285640
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: M_Pantetheine_4__phosphate_C11H21N2O7PS

425412
type: SpeciesReference
stoichiometry: 1.0
species: 284787

287818
type: Reaction
notes: GENE_ASSOCIATION: ( ( YCR024C-A and YEL017C-A and YGL008C ) or ( YCR024C-A and YEL017C-A and YPL036W ) ) PROTEIN_ASSOCIATION: ( Pma1 ) or ( Pma2 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: 3.6.3.6
fast: false
product: 359771
product: 359759
reactant: 359735
name: R_ATPase__cytosolic
product: 359783
reactant: 359747
kinetic law: 359795
reversible: false

359771
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stoichiometry: 1.0
species: 285751

285751
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Phosphate_HO4P

359759
type: SpeciesReference
stoichiometry: 1.0
species: 283602

283602
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_ADP_C10H12N5O10P2

359735
type: SpeciesReference
stoichiometry: 1.0
species: 283830

283830
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_ATP_C10H12N5O13P3

359783
type: SpeciesReference
stoichiometry: 1.0
species: 284790

284790
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_H_H

359747
type: SpeciesReference
stoichiometry: 1.0
species: 284757

293209
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value: -0.011879

293207
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value: 0.0

293205
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value: 0.0

293203
type: LocalParameter
value: 999999.0

293201
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value: 0.0

285844
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Proline_C5H9NO2

289309
type: Reaction
fast: false
name: R_glycine_cleavage_system__lipoamide__irreversible__mitochondrial
reversible: false
product: 393307
reactant: 393259
product: 393295
kinetic law: 393319
reactant: 393271
notes: GENE_ASSOCIATION: ( YDR019C and YMR189W and YAL044C and YFL018C ) PROTEIN_ASSOCIATION: ( Gcv1-m and Gcv2-m and Gcv3-m and PdE3-m ) SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 2.1.2.10
product: 393283

393307
type: SpeciesReference
stoichiometry: 1.0
species: 285460

285460
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Ammonium_H4N

282879
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

393259
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stoichiometry: 1.0
species: 283689

283689
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_S_aminomethyldihydrolipoamide_C9H21N2OS2

393295
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stoichiometry: 1.0
species: 285360

285360
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_5_10_Methylenetetrahydrofolate_C20H21N7O6

298331
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value: -0.011285

298329
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value: 0.0

298328
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value: 0.0

298326
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value: 999999.0

298325
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value: 0.0

393271
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stoichiometry: 1.0
species: 286174

286174
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_5_6_7_8_Tetrahydrofolate_C19H21N7O6

393283
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stoichiometry: 1.0
species: 284208

284208
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Dihydrolipoamide_C8H17NOS2

283587
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Adenine_C5H5N5

290274
type: Reaction
fast: false
kinetic law: 424289
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Riboflavin_Metabolism PROTEIN_CLASS:
name: R_pyrimidine_phosphatase
reversible: false
reactant: 424241
reactant: 424253
product: 424265
product: 424277

302012
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value: 0.0

302011
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value: 2.85E-4

302009
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302008
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302006
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424241
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stoichiometry: 1.0
species: 283371

283371
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_Amino_6__5__phosphoribitylamino_uracil_C9H15N4O9P

424253
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stoichiometry: 1.0
species: 284757

424265
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stoichiometry: 1.0
species: 283356

283356
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4__1_D_Ribitylamino__5_aminouracil_C9H16N4O6

424277
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stoichiometry: 1.0
species: 285751

289872
type: Reaction
kinetic law: 411522
product: 411509
reactant: 411497
notes: GENE_ASSOCIATION: YJL153C PROTEIN_ASSOCIATION: Ino1 SUBSYSTEM: S_Phospholipid_Biosynthesis PROTEIN_CLASS: 5.5.1.4
fast: false
reversible: false
name: R_myo_Inositol_1_phosphate_synthase

300300
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300299
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value: 0.001526

300297
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300296
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300294
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411509
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stoichiometry: 1.0
species: 285309

285309
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_1D_myo_Inositol_1_phosphate_C6H11O9P

411497
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stoichiometry: 1.0
species: 284523

284523
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Glucose_6_phosphate_C6H11O9P

288427
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reactant: 372979
reactant: 372967
reactant: 373015
reactant: 373003
notes: GENE_ASSOCIATION: YCR048W PROTEIN_ASSOCIATION: Are1 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS:
kinetic law: 373051
reactant: 372991
reactant: 372955
fast: false
reversible: false
product: 373039
product: 373027
name: R_Acyl_CoAepisterol_acyltransferase__yeast_specific
reactant: 372943

372979
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stoichiometry: 0.27
species: 285577

285577
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

372967
type: SpeciesReference
stoichiometry: 0.01
species: 284876

284876
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

373015
type: SpeciesReference
stoichiometry: 0.015
species: 286150

286150
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

373003
type: SpeciesReference
stoichiometry: 0.03
species: 286099

286099
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

295614
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value: 0.0

295611
type: LocalParameter
value: 0.0

295608
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value: 0.0

295605
type: LocalParameter
value: 999999.0

295602
type: LocalParameter
value: 0.0

372991
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stoichiometry: 0.02
species: 285775

285775
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

372955
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stoichiometry: 0.655
species: 284846

284846
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

373039
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stoichiometry: 0.01
species: 284340

284340
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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373027
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stoichiometry: 1.0
species: 284013

284013
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Coenzyme_A_C21H32N7O16P3S

372943
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stoichiometry: 0.01
species: 284334

284334
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_episterol_C28H46O

285511
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Oxaloacetate_C4H2O5

282885
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

288983
type: Reaction
kinetic law: 380486
product: 380474
reactant: 380462
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acyl_ACP_mitochondrial_transport

297241
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value: -0.079589

297239
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value: 0.0

297238
type: LocalParameter
value: 0.0

297237
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value: 999999.0

297235
type: LocalParameter
value: 0.0

380474
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stoichiometry: 1.0
species: 285372

285372
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

380462
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stoichiometry: 1.0
species: 285375

285375
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

288376
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fast: false
reversible: true
notes: GENE_ASSOCIATION: YKL217W PROTEIN_ASSOCIATION: Jen1 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
reactant: 372097
kinetic law: 372134
product: 372110
reactant: 372085
product: 372122
name: R_D_lactate_transport_via_proton_symport

372097
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stoichiometry: 1.0
species: 285110

285110
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Lactate_C3H5O3

295393
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value: 0.0

295390
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value: 0.0

295387
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value: 0.0

295384
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295381
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372110
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species: 284787

372085
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stoichiometry: 1.0
species: 284790

372122
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stoichiometry: 1.0
species: 285107

285107
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Lactate_C3H5O3

289275
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kinetic law: 392135
product: 392123
reactant: 392111
notes: GENE_ASSOCIATION: YBR196C PROTEIN_ASSOCIATION: Pgi1 SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 5.3.1.9
fast: false
reversible: true
name: R_Glucose_6_phosphate_isomerase

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298219
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value: 0.0

298217
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298216
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298215
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392123
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stoichiometry: 1.0
species: 284403

284403
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Fructose_6_phosphate_C6H11O9P

392111
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species: 284520

284520
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_beta_D_glucose_6_phosphate_C6H11O9P

290226
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product: 422418
reactant: 422406
reactant: 422382
reactant: 422394
product: 422442
fast: false
kinetic law: 422455
name: R_phenylalanyl_tRNA_synthetase__mitochondrial
product: 422430
reversible: false
notes: GENE_ASSOCIATION: YPR047W PROTEIN_ASSOCIATION: Msf1-m SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.20

422418
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stoichiometry: 1.0
species: 283716

283716
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_AMP_C10H12N5O7P

422406
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species: 286339

286339
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_tRNA_Phe__R

422382
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species: 283836

283836
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_ATP_C10H12N5O13P3

422394
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stoichiometry: 1.0
species: 285724

285724
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Phenylalanine_C9H11NO2

422442
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stoichiometry: 1.0
species: 285799

285799
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Diphosphate_HO7P2

301829
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value: -0.089488

301828
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value: 0.0

301825
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value: 0.0

301824
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value: 999999.0

301821
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422430
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stoichiometry: 1.0
species: 285739

285739
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Phenylalanyl_tRNA_Phe__C9H10NOR

284454
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_FMN_C17H19N4O9P

287935
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reactant: 362435
fast: false
product: 362447
kinetic law: 362471
notes: GENE_ASSOCIATION: ( YPL087W or YBR183W ) PROTEIN_ASSOCIATION: ( Ydc1 ) or ( Ypc1 ) SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
reactant: 362423
name: R_alkaline_ceramidase__ceramide_2___endoplasmic_reticulum
reactant: 362411
reversible: false
product: 362459

362435
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stoichiometry: 1.0
species: 284802

284802
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_H_H

282873
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

362447
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stoichiometry: 1.0
species: 284879

284879
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873

293578
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293576
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value: 0.0

293574
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293572
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value: 999999.0

293569
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362423
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stoichiometry: 1.0
species: 284022

284022
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Coenzyme_A_C21H32N7O16P3S

362411
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stoichiometry: 1.0
species: 283923

283923
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Ceramide_2__Phytosphingosinen_C260__C44H89NO4

362459
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species: 285886

285886
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Phytosphingosine_C18H40NO3

285919
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

289990
type: Reaction
notes: GENE_ASSOCIATION: YKL067W PROTEIN_ASSOCIATION: Ynk1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6
fast: false
product: 415455
reactant: 415442
product: 415467
kinetic law: 415479
reactant: 415430
reversible: true
name: R_nucleoside_diphosphate_kinase__ATPGDP_

415455
type: SpeciesReference
stoichiometry: 1.0
species: 283602

415442
type: SpeciesReference
stoichiometry: 1.0
species: 284562

284562
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_GDP_C10H12N5O11P2

415467
type: SpeciesReference
stoichiometry: 1.0
species: 284732

284732
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_GTP_C10H12N5O14P3

300782
type: LocalParameter
value: 0.0

300780
type: LocalParameter
value: 0.0

300779
type: LocalParameter
value: 0.0

300776
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value: 999999.0

300775
type: LocalParameter
value: -999999.0

415430
type: SpeciesReference
stoichiometry: 1.0
species: 283830

290574
type: Reaction
product: 433978
reversible: false
kinetic law: 434014
product: 433990
reactant: 433954
reactant: 433966
fast: false
name: R_Spermidine_acetyltransferase
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.3.1.57
product: 434002

433978
type: SpeciesReference
stoichiometry: 1.0
species: 283443

283443
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N1_Acetylspermidine_C9H23N3O

303061
type: LocalParameter
value: -0.061572

303059
type: LocalParameter
value: 0.0

303058
type: LocalParameter
value: 0.0

303056
type: LocalParameter
value: 999999.0

303055
type: LocalParameter
value: 0.0

433990
type: SpeciesReference
stoichiometry: 1.0
species: 284013

433954
type: SpeciesReference
stoichiometry: 1.0
species: 283521

283521
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Acetyl_CoA_C23H34N7O17P3S

433966
type: SpeciesReference
stoichiometry: 1.0
species: 286075

286075
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Spermidine_C7H22N3

434002
type: SpeciesReference
stoichiometry: 1.0
species: 284787

286741
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Fructose_C6H12O6

287455
type: Reaction
kinetic law: 351576
fast: false
reactant: 351527
product: 351551
name: R_adenosine_transport_in_via_proton_symport
reversible: false
notes: GENE_ASSOCIATION: YAL022C PROTEIN_ASSOCIATION: Fun26 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
product: 351563
reactant: 351539

292107
type: LocalParameter
value: 0.0

292105
type: LocalParameter
value: 0.0

292103
type: LocalParameter
value: 0.0

292101
type: LocalParameter
value: 999999.0

292099
type: LocalParameter
value: 0.0

351527
type: SpeciesReference
stoichiometry: 1.0
species: 283596

283596
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Adenosine_C10H13N5O4

351551
type: SpeciesReference
stoichiometry: 1.0
species: 283593

283593
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Adenosine_C10H13N5O4

351563
type: SpeciesReference
stoichiometry: 1.0
species: 284787

351539
type: SpeciesReference
stoichiometry: 1.0
species: 284790

283530
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Acetyl_CoA_C23H34N7O17P3S

288911
type: Reaction
kinetic law: 379542
product: 379530
reactant: 379518
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Thiamin_monophosphate_exchange

297050
type: LocalParameter
value: -0.123145

297048
type: LocalParameter
value: 0.0

297047
type: LocalParameter
value: 0.0

297046
type: LocalParameter
value: 999999.0

297044
type: LocalParameter
value: 0.0

379530
type: SpeciesReference
stoichiometry: 1.0
species: 286996

286996
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Thiamin_monophosphate_C12H16N4O4PS

379518
type: SpeciesReference
stoichiometry: 1.0
species: 286189

286189
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Thiamin_monophosphate_C12H16N4O4PS

285168
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Lysine_C6H15N2O2

286819
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Isoamyl_alcohol_C5H12O

289313
type: Reaction
reactant: 393417
name: R_glycine_cleavage_complex__lipoylprotein___mitochondrial
fast: false
reversible: true
kinetic law: 393465
product: 393453
notes: GENE_ASSOCIATION: ( YDR019C and YMR189W and YAL044C and YFL018C ) PROTEIN_ASSOCIATION: ( Gcv1-m and Gcv2-m and Gcv3-m and PdE3-m ) SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 1.4.4.2
reactant: 393429
product: 393441
reactant: 393405

393417
type: SpeciesReference
stoichiometry: 1.0
species: 284796

284796
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_H_H

298344
type: LocalParameter
value: 0.0

298342
type: LocalParameter
value: 0.0

298341
type: LocalParameter
value: 0.0

298339
type: LocalParameter
value: 999999.0

298338
type: LocalParameter
value: -999999.0

393453
type: SpeciesReference
stoichiometry: 1.0
species: 284001

284001
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_CO2_CO2

393429
type: SpeciesReference
stoichiometry: 1.0
species: 285165

285165
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Lipoylprotein_S2X

393441
type: SpeciesReference
stoichiometry: 1.0
species: 283692

283692
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_S_Aminomethyldihydrolipoylprotein_CH6NS2X

393405
type: SpeciesReference
stoichiometry: 1.0
species: 284663

284663
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Glycine_C2H5NO2

285318
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_myo_Inositol_hexakisphosphate_C6H6O24P6

282882
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

284753
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_Hydrogen_peroxide_H2O2

288319
type: Reaction
product: 370852
kinetic law: 370888
reversible: false
name: R_dephospho_CoA_kinase
reactant: 370828
fast: false
reactant: 370840
product: 370864
product: 370876
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 2.7.1.24

370852
type: SpeciesReference
stoichiometry: 1.0
species: 283602

295146
type: LocalParameter
value: 0.0

295143
type: LocalParameter
value: 0.0

295140
type: LocalParameter
value: 0.0

295137
type: LocalParameter
value: 999999.0

295134
type: LocalParameter
value: 0.0

370828
type: SpeciesReference
stoichiometry: 1.0
species: 283830

370840
type: SpeciesReference
stoichiometry: 1.0
species: 284268

284268
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Dephospho_CoA_C21H33N7O13P2S

370864
type: SpeciesReference
stoichiometry: 1.0
species: 284013

370876
type: SpeciesReference
stoichiometry: 1.0
species: 284787

289447
type: Reaction
kinetic law: 397803
product: 397791
reactant: 397778
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: false
name: R_oxidized_glutathione_irreversible_uniport

298801
type: LocalParameter
value: 0.0

298800
type: LocalParameter
value: 0.0

298798
type: LocalParameter
value: 0.0

298797
type: LocalParameter
value: 999999.0

298796
type: LocalParameter
value: 0.0

397791
type: SpeciesReference
stoichiometry: 1.0
species: 284711

284711
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Oxidized_glutathione_C20H30N6O12S2

397778
type: SpeciesReference
stoichiometry: 1.0
species: 284714

284714
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Oxidized_glutathione_C20H30N6O12S2

287785
type: Reaction
reactant: 358997
notes: GENE_ASSOCIATION: ( YFL055W or YKR039W or YPL265W ) PROTEIN_ASSOCIATION: ( Agp3 ) or ( Gap1 ) or ( Dip5 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
kinetic law: 359045
reactant: 359009
product: 359021
reversible: true
product: 359033
name: R_L_aspartate_reversible_transport_via_proton_symport
fast: false

358997
type: SpeciesReference
stoichiometry: 1.0
species: 283803

283803
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Aspartate_C4H6NO4

293110
type: LocalParameter
value: 0.0

293108
type: LocalParameter
value: 0.0

293106
type: LocalParameter
value: 0.0

293104
type: LocalParameter
value: 999999.0

293102
type: LocalParameter
value: -999999.0

359009
type: SpeciesReference
stoichiometry: 1.0
species: 284790

359021
type: SpeciesReference
stoichiometry: 1.0
species: 283800

283800
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Aspartate_C4H6NO4

359033
type: SpeciesReference
stoichiometry: 1.0
species: 284787

289217
type: Reaction
product: 390215
fast: false
reactant: 390179
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Fructose_and_Mannose_Metabolism PROTEIN_CLASS: 2.7.1.56
reactant: 390191
kinetic law: 390239
name: R_fructose_1_phosphate_kinase
product: 390203
reversible: false
product: 390227

390215
type: SpeciesReference
stoichiometry: 1.0
species: 284418

284418
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Fructose_1_6_bisphosphate_C6H10O12P2

390179
type: SpeciesReference
stoichiometry: 1.0
species: 283830

390191
type: SpeciesReference
stoichiometry: 1.0
species: 284397

284397
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Fructose_1_phosphate_C6H11O9P

298032
type: LocalParameter
value: -0.007721

298030
type: LocalParameter
value: 0.0

298029
type: LocalParameter
value: 0.0

298027
type: LocalParameter
value: 999999.0

298026
type: LocalParameter
value: 0.0

390203
type: SpeciesReference
stoichiometry: 1.0
species: 283602

390227
type: SpeciesReference
stoichiometry: 1.0
species: 284787

284472
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Formate_CH1O2

283701
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_S_Adenosyl_L_methionine_C15H23N6O5S

285892
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

284271
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Dephospho_CoA_C21H33N7O13P2S

287361
type: Reaction
kinetic law: 349737
product: 349725
reactant: 349713
notes: GENE_ASSOCIATION: YLR304C PROTEIN_ASSOCIATION: Aco1 SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: 4.2.1.3
fast: false
reversible: true
name: R_aconitase

291817
type: LocalParameter
value: 0.0

291815
type: LocalParameter
value: 0.266055

291813
type: LocalParameter
value: 0.0

291811
type: LocalParameter
value: 999999.0

291809
type: LocalParameter
value: -999999.0

349725
type: SpeciesReference
stoichiometry: 1.0
species: 284984

284984
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Isocitrate_C6H5O7

349713
type: SpeciesReference
stoichiometry: 1.0
species: 283962

283962
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Citrate_C6H5O7

284388
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ethanol_C2H6O

290482
type: Reaction
name: R_ribonucleoside_diphosphate_reductase__ADP_
reactant: 430915
kinetic law: 430963
reversible: false
product: 430939
notes: GENE_ASSOCIATION: ( ( ( YIL066C and YJL026W ) and YLR043C ) or ( ( YIL066C and YJL026W ) and YGR209C ) or ( ( YER070W and YJL026W ) and YLR043C ) or ( ( YER070W and YJL026W ) and YGR209C ) ) PROTEIN_ASSOCIATION: ( Rnr32 and Trx1 ) or ( Rnr32 and Trx2 ) or ( Rnr12 and Trx1 ) or ( Rnr12 and Trx2 ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 1.17.4.1
product: 430951
product: 430927
reactant: 430903
fast: false

430915
type: SpeciesReference
stoichiometry: 1.0
species: 286243

286243
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Reduced_thioredoxin_XH2

302739
type: LocalParameter
value: 0.0

302737
type: LocalParameter
value: 0.0

302736
type: LocalParameter
value: 0.0

302734
type: LocalParameter
value: 999999.0

302733
type: LocalParameter
value: 0.0

430939
type: SpeciesReference
stoichiometry: 1.0
species: 284757

430951
type: SpeciesReference
stoichiometry: 1.0
species: 286231

286231
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Oxidized_thioredoxin_X

430927
type: SpeciesReference
stoichiometry: 1.0
species: 284085

284085
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_dADP_C10H12N5O9P2

430903
type: SpeciesReference
stoichiometry: 1.0
species: 283602

287713
type: Reaction
name: R_L_arganine_reversible_transport_via_proton_symport
kinetic law: 357390
product: 357366
notes: GENE_ASSOCIATION: ( YKR039W or YEL063C or YNL270C ) PROTEIN_ASSOCIATION: ( Gap1 ) or ( Can1 ) or ( Alp1 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
product: 357378
reversible: true
fast: false
reactant: 357354
reactant: 357342

292892
type: LocalParameter
value: 0.0

292890
type: LocalParameter
value: 0.0

292888
type: LocalParameter
value: 0.0

292886
type: LocalParameter
value: 999999.0

292884
type: LocalParameter
value: -999999.0

357366
type: SpeciesReference
stoichiometry: 1.0
species: 283761

283761
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Arginine_C6H15N4O2

357378
type: SpeciesReference
stoichiometry: 1.0
species: 284787

357354
type: SpeciesReference
stoichiometry: 1.0
species: 284790

357342
type: SpeciesReference
stoichiometry: 1.0
species: 283764

283764
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Arginine_C6H15N4O2

287346
type: Reaction
reactant: 349422
notes: GENE_ASSOCIATION: YGL205W PROTEIN_ASSOCIATION: Pox1-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 1.3.3.6
kinetic law: 349458
reversible: false
product: 349434
reactant: 349410
fast: false
product: 349446
name: R_acyl_CoA_oxidase__octadecanoyl_CoA___peroxisomal

349422
type: SpeciesReference
stoichiometry: 1.0
species: 286102

286102
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

291772
type: LocalParameter
value: 0.0

291770
type: LocalParameter
value: 0.0

291768
type: LocalParameter
value: 0.0

291766
type: LocalParameter
value: 999999.0

291765
type: LocalParameter
value: 0.0

349434
type: SpeciesReference
stoichiometry: 1.0
species: 284754

284754
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Hydrogen_peroxide_H2O2

349410
type: SpeciesReference
stoichiometry: 1.0
species: 285499

285499
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_O2_O2

349446
type: SpeciesReference
stoichiometry: 1.0
species: 285574

285574
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

283302
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Hydroxybenzoate_C7H5O3

287848
type: Reaction
kinetic law: 360525
reactant: 360489
product: 360513
notes: GENE_ASSOCIATION: YGR065C PROTEIN_ASSOCIATION: Vht1 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
name: R_Biotin_uptake
reactant: 360476
product: 360501
reversible: false

293300
type: LocalParameter
value: 0.0

293298
type: LocalParameter
value: 0.0

293296
type: LocalParameter
value: 0.0

293294
type: LocalParameter
value: 999999.0

293292
type: LocalParameter
value: 0.0

360489
type: SpeciesReference
stoichiometry: 1.0
species: 284790

360513
type: SpeciesReference
stoichiometry: 1.0
species: 284787

360476
type: SpeciesReference
stoichiometry: 1.0
species: 283863

283863
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Biotin_C10H15N2O3S

360501
type: SpeciesReference
stoichiometry: 1.0
species: 283860

283860
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Biotin_C10H15N2O3S

286474
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_____Ureidoglycolate_C3H5N2O4

288458
type: Reaction
kinetic law: 373979
product: 373967
reactant: 373955
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Endoplasmic_Reticular PROTEIN_CLASS:
fast: false
reversible: true
name: R_Ergosta_5_6_22_24__28__tetraen_3beta_ol_endoplamic_reticular_transport

295757
type: LocalParameter
value: 0.0

295754
type: LocalParameter
value: 2.02E-4

295751
type: LocalParameter
value: 0.0

295748
type: LocalParameter
value: 999999.0

295745
type: LocalParameter
value: -999999.0

373967
type: SpeciesReference
stoichiometry: 1.0
species: 284370

284370
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Ergosta_5_7_22_24__28__tetraen_3beta_ol_C28H42O

373955
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stoichiometry: 1.0
species: 284367

284367
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ergosta_5_7_22_24__28__tetraen_3beta_ol_C28H42O

289628
type: Reaction
kinetic law: 403332
product: 403320
reactant: 403308
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_Indoleacetaldehyde_transport__extracellular_

299416
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value: 0.0

299414
type: LocalParameter
value: 0.0

299413
type: LocalParameter
value: 0.0

299411
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value: 999999.0

299410
type: LocalParameter
value: -999999.0

403320
type: SpeciesReference
stoichiometry: 1.0
species: 284996

284996
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Indole_3_acetaldehyde_C10H9NO

403308
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stoichiometry: 1.0
species: 284993

284993
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Indole_3_acetaldehyde_C10H9NO

286090
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Squalene_C30H50

288584
type: Reaction
kinetic law: 375573
product: 375561
reactant: 375548
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Carnitine_exchange

296178
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value: 0.0

296176
type: LocalParameter
value: 0.0

296175
type: LocalParameter
value: 0.0

296174
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value: 999999.0

296172
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value: 0.0

375561
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stoichiometry: 1.0
species: 286669

286669
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Carnitine_C7H15NO3

375548
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stoichiometry: 1.0
species: 284037

284037
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Carnitine_C7H15NO3

290816
type: Reaction
reactant: 442001
reactant: 441989
fast: false
product: 442050
notes: GENE_ASSOCIATION: YGR094W PROTEIN_ASSOCIATION: Vas1-m SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.9
kinetic law: 442062
product: 442026
reversible: false
reactant: 442014
product: 442038
name: R_valyl_tRNA_synthetase__mitochondrial

442001
type: SpeciesReference
stoichiometry: 1.0
species: 286369

286369
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_tRNA_Val__R

441989
type: SpeciesReference
stoichiometry: 1.0
species: 283836

442050
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stoichiometry: 1.0
species: 286507

286507
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Valyl_tRNA_Val__C5H10NOR

303918
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value: -0.029103

303917
type: LocalParameter
value: 0.0

303915
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value: 0.0

303914
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value: 999999.0

303912
type: LocalParameter
value: 0.0

442026
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stoichiometry: 1.0
species: 283716

442014
type: SpeciesReference
stoichiometry: 1.0
species: 286501

286501
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Valine_C5H11NO2

442038
type: SpeciesReference
stoichiometry: 1.0
species: 285799

286888
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870

290830
type: Reaction
fast: false
product: 442462
reversible: false
kinetic law: 442486
notes: GENE_ASSOCIATION: YHR104W PROTEIN_ASSOCIATION: Gre3 SUBSYSTEM: S_Xylose_Metabolism PROTEIN_CLASS: 1.1.1.21
product: 442474
reactant: 442450
name: R_xylose_reductase
reactant: 442425
reactant: 442438

442462
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stoichiometry: 1.0
species: 285421

285421
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

303967
type: LocalParameter
value: 0.0

303966
type: LocalParameter
value: 0.0

303964
type: LocalParameter
value: 0.0

303963
type: LocalParameter
value: 999999.0

303961
type: LocalParameter
value: 0.0

442474
type: SpeciesReference
stoichiometry: 1.0
species: 286534

286534
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Xylitol_C5H12O5

442450
type: SpeciesReference
stoichiometry: 1.0
species: 286528

286528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Xylose_C5H10O5

442425
type: SpeciesReference
stoichiometry: 1.0
species: 284787

442438
type: SpeciesReference
stoichiometry: 1.0
species: 285436

285436
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

282950
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_3_Disphospho_D_glycerate_C3H3O10P2

284824
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Homocysteine_C4H9NO2S

286726
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Fe2_Fe

285074
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

284687
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Glycyl_tRNA_Gly__C2H4NOR

283755
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Arabinose_C5H10O5

287965
type: Reaction
product: 363229
product: 363205
reversible: false
reactant: 363180
notes: GENE_ASSOCIATION: ( YHL003C or YKL008C or YBR183W ) PROTEIN_ASSOCIATION: ( Lag1 ) or ( Lac1 ) or ( Ypc1 ) SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
product: 363217
kinetic law: 363241
name: R_Ceramide_2_synthase__26C___endoplasmic_reticular
reactant: 363193
fast: false

363229
type: SpeciesReference
stoichiometry: 1.0
species: 284802

363205
type: SpeciesReference
stoichiometry: 1.0
species: 283923

363180
type: SpeciesReference
stoichiometry: 1.0
species: 284879

363217
type: SpeciesReference
stoichiometry: 1.0
species: 284022

293679
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value: 0.0

293677
type: LocalParameter
value: 0.0

293675
type: LocalParameter
value: 0.0

293673
type: LocalParameter
value: 999999.0

293670
type: LocalParameter
value: 0.0

363193
type: SpeciesReference
stoichiometry: 1.0
species: 285886

290256
type: Reaction
name: R_phosphate_peroxisomal_transport_via_proton_symport
product: 423452
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
product: 423440
reversible: true
reactant: 423416
reactant: 423428
kinetic law: 423464

423452
type: SpeciesReference
stoichiometry: 1.0
species: 285772

285772
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Phosphate_HO4P

423440
type: SpeciesReference
stoichiometry: 1.0
species: 284808

284808
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_H_H

423416
type: SpeciesReference
stoichiometry: 1.0
species: 284787

423428
type: SpeciesReference
stoichiometry: 1.0
species: 285751

301949
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value: 0.0

301948
type: LocalParameter
value: 0.0

301946
type: LocalParameter
value: 0.0

301945
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value: 999999.0

301943
type: LocalParameter
value: -999999.0

288575
type: Reaction
kinetic law: 375464
product: 375452
reactant: 375440
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Choline_exchange

296154
type: LocalParameter
value: -0.129876

296152
type: LocalParameter
value: 0.0

296151
type: LocalParameter
value: 0.0

296150
type: LocalParameter
value: 999999.0

296148
type: LocalParameter
value: 0.0

375452
type: SpeciesReference
stoichiometry: 1.0
species: 286660

286660
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Choline_C5H14NO

375440
type: SpeciesReference
stoichiometry: 1.0
species: 283953

283953
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Choline_C5H14NO

289029
type: Reaction
kinetic law: 381547
reactant: 381487
product: 381523
reactant: 381475
reversible: false
fast: false
notes: GENE_ASSOCIATION: ( YPL147W and YKL188C ) PROTEIN_ASSOCIATION: ( Pxa1-p and Pxa2-p ) SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
name: R_fatty_acyl_CoA_transport_via_ABC_system
product: 381511
product: 381535
reactant: 381463
product: 381499

297367
type: LocalParameter
value: -0.032073

297365
type: LocalParameter
value: 0.0

297364
type: LocalParameter
value: 0.0

297363
type: LocalParameter
value: 999999.0

297361
type: LocalParameter
value: 0.0

381487
type: SpeciesReference
stoichiometry: 1.0
species: 284778

284778
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_H2O_H2O

381523
type: SpeciesReference
stoichiometry: 1.0
species: 285772

381475
type: SpeciesReference
stoichiometry: 1.0
species: 283845

283845
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_ATP_C10H12N5O13P3

381511
type: SpeciesReference
stoichiometry: 1.0
species: 284808

381535
type: SpeciesReference
stoichiometry: 1.0
species: 286102

381463
type: SpeciesReference
stoichiometry: 1.0
species: 286099

381499
type: SpeciesReference
stoichiometry: 1.0
species: 283617

283617
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_ADP_C10H12N5O10P2

288941
type: Reaction
kinetic law: 379906
product: 379894
reactant: 379881
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Urea_exchange

297129
type: LocalParameter
value: -0.063552

297127
type: LocalParameter
value: 0.0

297126
type: LocalParameter
value: 0.0

297125
type: LocalParameter
value: 999999.0

297123
type: LocalParameter
value: 0.0

379894
type: SpeciesReference
stoichiometry: 1.0
species: 287026

287026
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Urea_CH4N2O

379881
type: SpeciesReference
stoichiometry: 1.0
species: 286480

286480
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Urea_CH4N2O

289632
type: Reaction
product: 403404
fast: false
product: 403428
reactant: 403380
name: R_Imidazole_glycerol_3_phosphate_synthase
product: 403416
notes: GENE_ASSOCIATION: YBR248C PROTEIN_ASSOCIATION: His7 SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS:
reactant: 403392
product: 403440
reversible: false
kinetic law: 403452

403404
type: SpeciesReference
stoichiometry: 1.0
species: 283635

283635
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_Amino_1__5_Phospho_D_ribosyl_imidazole_4_carboxamide_C9H13N4O8P

403428
type: SpeciesReference
stoichiometry: 1.0
species: 284618

284618
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Glutamate_C5H8NO4

403380
type: SpeciesReference
stoichiometry: 1.0
species: 284595

284595
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Glutamine_C5H10N2O3

403416
type: SpeciesReference
stoichiometry: 1.0
species: 284331

284331
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_erythro_1__Imidazol_4_yl_glycerol_3_phosphate_C6H9N2O6P

403392
type: SpeciesReference
stoichiometry: 1.0
species: 285838

285838
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

403440
type: SpeciesReference
stoichiometry: 1.0
species: 284787

299430
type: LocalParameter
value: 0.0

299428
type: LocalParameter
value: 0.019085

299427
type: LocalParameter
value: 0.0

299425
type: LocalParameter
value: 999999.0

299424
type: LocalParameter
value: 0.0

285718
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Phenylalanine_C9H11NO2

284337
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_episterol_C28H46O

289822
type: Reaction
product: 409809
reactant: 409785
name: R_malic_enzyme__NAD___mitochondrial
fast: false
product: 409821
product: 409797
kinetic law: 409833
reversible: false
notes: GENE_ASSOCIATION: YKL029C PROTEIN_ASSOCIATION: Mae1-m SUBSYSTEM: S_Anaplerotic_reactions PROTEIN_CLASS: 1.1.1.38
reactant: 409773

409809
type: SpeciesReference
stoichiometry: 1.0
species: 285412

285412
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

409785
type: SpeciesReference
stoichiometry: 1.0
species: 285399

285399
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

409821
type: SpeciesReference
stoichiometry: 1.0
species: 285949

285949
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Pyruvate_C3H3O3

409797
type: SpeciesReference
stoichiometry: 1.0
species: 284001

300120
type: LocalParameter
value: -0.008909

300119
type: LocalParameter
value: 0.0

300116
type: LocalParameter
value: 0.0

300115
type: LocalParameter
value: 999999.0

300112
type: LocalParameter
value: 0.0

409773
type: SpeciesReference
stoichiometry: 1.0
species: 285213

285213
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Malate_C4H4O5

289233
type: Reaction
product: 390807
product: 390795
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 3.7.1.2
reactant: 390771
product: 390819
name: R_fumarylacetoacetase
reversible: false
reactant: 390783
kinetic law: 390832
fast: false

390807
type: SpeciesReference
stoichiometry: 1.0
species: 284493

284493
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Fumarate_C4H2O4

390795
type: SpeciesReference
stoichiometry: 1.0
species: 283509

283509
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Acetoacetate_C4H5O3

390771
type: SpeciesReference
stoichiometry: 1.0
species: 283284

283284
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Fumarylacetoacetate_C8H6O6

390819
type: SpeciesReference
stoichiometry: 1.0
species: 284787

390783
type: SpeciesReference
stoichiometry: 1.0
species: 284757

298084
type: LocalParameter
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298082
type: LocalParameter
value: 0.0

298081
type: LocalParameter
value: 0.0

298079
type: LocalParameter
value: 999999.0

298078
type: LocalParameter
value: 0.0

287917
type: Reaction
kinetic law: 362108
product: 362096
reactant: 362084
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Endoplasmic_Reticular PROTEIN_CLASS:
fast: false
reversible: true
name: R_ceramide_1__C26__endoplasmic_reticular_transport

293518
type: LocalParameter
value: 0.0

293516
type: LocalParameter
value: 0.0

293514
type: LocalParameter
value: 0.0

293512
type: LocalParameter
value: 999999.0

293509
type: LocalParameter
value: -999999.0

362096
type: SpeciesReference
stoichiometry: 1.0
species: 283911

283911
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Ceramide_1__Sphinganinen_C260__C44H89NO3

362084
type: SpeciesReference
stoichiometry: 1.0
species: 283908

283908
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_1__Sphinganinen_C260__C44H89NO3

285757
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282876
name: M_Phosphate_HO4P

282876
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

290406
type: Reaction
fast: false
kinetic law: 428572
reversible: false
reactant: 428520
product: 428546
reactant: 428533
product: 428559
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 2.7.7.3
reactant: 428508
name: R_panthetheine_phosphate_adenylyltransferase

302473
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302471
type: LocalParameter
value: 0.0

302470
type: LocalParameter
value: 0.0

302468
type: LocalParameter
value: 999999.0

302467
type: LocalParameter
value: 0.0

428520
type: SpeciesReference
stoichiometry: 1.0
species: 284796

428546
type: SpeciesReference
stoichiometry: 1.0
species: 284271

428533
type: SpeciesReference
stoichiometry: 1.0
species: 285643

285643
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Pantetheine_4__phosphate_C11H21N2O7PS

428559
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stoichiometry: 1.0
species: 285799

428508
type: SpeciesReference
stoichiometry: 1.0
species: 283836

290518
type: Reaction
product: 432222
name: R_S_adenosyl_methionine_delta_24_sterol_c_methyltransferase
product: 432210
kinetic law: 432246
fast: false
reactant: 432198
reversible: false
notes: GENE_ASSOCIATION: YML008C PROTEIN_ASSOCIATION: Erg6 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS: 2.1.1.41
product: 432234
reactant: 432186

432222
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species: 284430

284430
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_fecosterol_C28H46O

432210
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stoichiometry: 1.0
species: 283626

283626
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_S_Adenosyl_L_homocysteine_C14H20N6O5S

302865
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302863
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value: 0.0

302862
type: LocalParameter
value: 0.0

302860
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302859
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432198
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stoichiometry: 1.0
species: 286549

286549
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_zymosterol_C27H44O

432234
type: SpeciesReference
stoichiometry: 1.0
species: 284787

432186
type: SpeciesReference
stoichiometry: 1.0
species: 283695

283695
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_S_Adenosyl_L_methionine_C15H23N6O5S

288503
type: Reaction
kinetic law: 374595
product: 374583
reactant: 374571
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_3mop_exchange

295952
type: LocalParameter
value: -0.043754

295949
type: LocalParameter
value: 0.0

295946
type: LocalParameter
value: 0.0

295943
type: LocalParameter
value: 999999.0

295940
type: LocalParameter
value: 0.0

374583
type: SpeciesReference
stoichiometry: 1.0
species: 286588

286588
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M__S__3_Methyl_2_oxopentanoate_C6H9O3

374571
type: SpeciesReference
stoichiometry: 1.0
species: 283203

283203
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M__S__3_Methyl_2_oxopentanoate_C6H9O3

290532
type: Reaction
kinetic law: 432658
product: 432646
reactant: 432634
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_sorbitol_transport_via_passive_diffusion

302914
type: LocalParameter
value: 0.0

302912
type: LocalParameter
value: 0.0

302911
type: LocalParameter
value: 0.0

302909
type: LocalParameter
value: 999999.0

302908
type: LocalParameter
value: -999999.0

432646
type: SpeciesReference
stoichiometry: 1.0
species: 286018

286018
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Sorbitol_C6H14O6

432634
type: SpeciesReference
stoichiometry: 1.0
species: 286021

286021
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Sorbitol_C6H14O6

288638
type: Reaction
kinetic law: 376224
product: 376212
reactant: 376200
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Ethanol_exchange

296322
type: LocalParameter
value: 0.0

296320
type: LocalParameter
value: 15.815475

296319
type: LocalParameter
value: 0.0

296318
type: LocalParameter
value: 999999.0

296316
type: LocalParameter
value: 0.0

376212
type: SpeciesReference
stoichiometry: 1.0
species: 286723

286723
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Ethanol_C2H6O

376200
type: SpeciesReference
stoichiometry: 1.0
species: 284391

284391
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Ethanol_C2H6O

288340
type: Reaction
reactant: 371346
product: 371382
kinetic law: 371394
name: R_2_5_diamino_6_ribosylamino_4_3H__pyrimidinone_5__phosphate_reductase__nadph_
fast: false
reactant: 371334
reactant: 371358
product: 371370
notes: GENE_ASSOCIATION: YBR153W PROTEIN_ASSOCIATION: Rib7 SUBSYSTEM: S_Riboflavin_Metabolism PROTEIN_CLASS:
reversible: false

371346
type: SpeciesReference
stoichiometry: 1.0
species: 284787

371382
type: SpeciesReference
stoichiometry: 1.0
species: 285421

295237
type: LocalParameter
value: 0.0

295234
type: LocalParameter
value: 2.85E-4

295231
type: LocalParameter
value: 0.0

295228
type: LocalParameter
value: 999999.0

295225
type: LocalParameter
value: 0.0

371334
type: SpeciesReference
stoichiometry: 1.0
species: 282956

282956
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_5_Diamino_6_hydroxy_4__5__phosphoribosylamino__pyrimidine_C9H14N5O8P

371358
type: SpeciesReference
stoichiometry: 1.0
species: 285436

371370
type: SpeciesReference
stoichiometry: 1.0
species: 282959

282959
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_5_diamino_6_ribitylamino_4_3H__pyrimidinone_5__phosphate_C9H16N5O8P

290722
type: Reaction
reactant: 438914
reactant: 438987
product: 439024
reversible: false
reactant: 438975
reactant: 438927
reactant: 438999
notes: GENE_ASSOCIATION: ( YOR245C or YCR048W or YNR019W ) PROTEIN_ASSOCIATION: ( Dga1 ) or ( Are1 ) or ( Are2 ) SUBSYSTEM: S_Glycerolipid_Metabolism PROTEIN_CLASS:
name: R_triglycerol_synthesis
reactant: 438902
kinetic law: 439036
reactant: 438939
reactant: 438963
fast: false
product: 439012
reactant: 438951

438914
type: SpeciesReference
stoichiometry: 0.02
species: 284124

284124
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

438987
type: SpeciesReference
stoichiometry: 0.05
species: 286099

439024
type: SpeciesReference
stoichiometry: 0.01
species: 286267

286267
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

438975
type: SpeciesReference
stoichiometry: 0.27
species: 285775

438927
type: SpeciesReference
stoichiometry: 0.06
species: 284169

284169
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

438999
type: SpeciesReference
stoichiometry: 0.1
species: 286150

438902
type: SpeciesReference
stoichiometry: 0.01
species: 282893

282893
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

303589
type: LocalParameter
value: 0.0

303588
type: LocalParameter
value: 0.0

303586
type: LocalParameter
value: 0.0

303585
type: LocalParameter
value: 999999.0

303583
type: LocalParameter
value: 0.0

438939
type: SpeciesReference
stoichiometry: 0.17
species: 284846

438963
type: SpeciesReference
stoichiometry: 0.24
species: 285577

439012
type: SpeciesReference
stoichiometry: 1.0
species: 284013

438951
type: SpeciesReference
stoichiometry: 0.09
species: 285556

285556
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

285171
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Lysine_C6H15N2O2

284529
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_alpha_D_Galactose_1_phosphate_C6H11O9P

286930
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Phenylalanine_C9H11NO2

286414
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_tetradecenoate__n_C141__C14H25O2

289485
type: Reaction
kinetic law: 398974
product: 398962
reactant: 398950
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_H2O_transport__mitochondrial

298931
type: LocalParameter
value: 0.0

298929
type: LocalParameter
value: -7.468244

298928
type: LocalParameter
value: 0.0

298926
type: LocalParameter
value: 999999.0

298925
type: LocalParameter
value: -999999.0

398962
type: SpeciesReference
stoichiometry: 1.0
species: 284766

284766
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_H2O_H2O

398950
type: SpeciesReference
stoichiometry: 1.0
species: 284757

285291
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_1D_myo_Inositol_1_3_4_5_6_pentakisphosphate_C6H7O21P5

290306
type: Reaction
reversible: false
fast: false
product: 425364
reactant: 425340
name: R_porphobilinogen_synthase
product: 425376
kinetic law: 425388
product: 425352
notes: GENE_ASSOCIATION: YGL040C PROTEIN_ASSOCIATION: Hem2 SUBSYSTEM: S_Porphyrin_and_Chlorophyll_Metabolism PROTEIN_CLASS: 4.2.1.24

425364
type: SpeciesReference
stoichiometry: 2.0
species: 284757

425340
type: SpeciesReference
stoichiometry: 2.0
species: 283362

283362
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_Amino_4_oxopentanoate_C5H9NO3

425376
type: SpeciesReference
stoichiometry: 1.0
species: 285787

285787
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Porphobilinogen_C10H13N2O4

302123
type: LocalParameter
value: 0.0

302121
type: LocalParameter
value: 0.0

302120
type: LocalParameter
value: 0.0

302118
type: LocalParameter
value: 999999.0

302117
type: LocalParameter
value: 0.0

425352
type: SpeciesReference
stoichiometry: 1.0
species: 284787

284741
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Guanine_C5H5N5O

289411
type: Reaction
kinetic law: 396555
product: 396543
reactant: 396531
notes: GENE_ASSOCIATION: YLL043W PROTEIN_ASSOCIATION: Fps1 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_glycerol_transport_via_channel

298673
type: LocalParameter
value: 0.0

298671
type: LocalParameter
value: 0.0

298670
type: LocalParameter
value: 0.0

298668
type: LocalParameter
value: 999999.0

298667
type: LocalParameter
value: -999999.0

396543
type: SpeciesReference
stoichiometry: 1.0
species: 284678

284678
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Glycerol_C3H8O3

396531
type: SpeciesReference
stoichiometry: 1.0
species: 284675

284675
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Glycerol_C3H8O3

282974
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_2_Amino_3_oxobutanoate_C4H7NO3

287878
type: Reaction
name: R_C_4_sterol_methyl_oxidase__4_4_dimethylzymosterol_
reactant: 361274
reactant: 361286
product: 361334
product: 361310
reactant: 361261
kinetic law: 361346
fast: false
reversible: false
notes: GENE_ASSOCIATION: YGR060W PROTEIN_ASSOCIATION: Erg25 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS:
product: 361322
reactant: 361298

361274
type: SpeciesReference
stoichiometry: 3.0
species: 284787

361286
type: SpeciesReference
stoichiometry: 3.0
species: 285436

361334
type: SpeciesReference
stoichiometry: 3.0
species: 285421

361310
type: SpeciesReference
stoichiometry: 1.0
species: 283341

283341
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Methylzymosterol_intermediate_1_C29H46O3

361261
type: SpeciesReference
stoichiometry: 1.0
species: 283245

283245
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_4_dimethylzymosterol_C29H48O

293392
type: LocalParameter
value: 0.0

293390
type: LocalParameter
value: 6.33E-4

293388
type: LocalParameter
value: 0.0

293386
type: LocalParameter
value: 999999.0

293383
type: LocalParameter
value: 0.0

361322
type: SpeciesReference
stoichiometry: 4.0
species: 284757

361298
type: SpeciesReference
stoichiometry: 3.0
species: 285487

285487
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_O2_O2

288488
type: Reaction
kinetic law: 374415
product: 374403
reactant: 374390
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_methyl_1_butanol_exchange

295887
type: LocalParameter
value: 0.0

295884
type: LocalParameter
value: 0.0

295881
type: LocalParameter
value: 0.0

295878
type: LocalParameter
value: 999999.0

295875
type: LocalParameter
value: 0.0

374403
type: SpeciesReference
stoichiometry: 1.0
species: 286573

286573
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_2_methyl_1_butanol_C5H12O

374390
type: SpeciesReference
stoichiometry: 1.0
species: 283056

283056
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_2_methyl_1_butanol_C5H12O

289069
type: Reaction
reactant: 382933
reactant: 382958
name: R_fatty_acid__CoA_ligase__octadecanoate_
product: 382994
reversible: true
kinetic law: 383006
product: 382970
notes: GENE_ASSOCIATION: ( YOR317W or YIL009W or YMR246W ) PROTEIN_ASSOCIATION: ( Faa1 ) or ( Faa3 ) or ( Faa4 ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 6.2.1.3
product: 382982
reactant: 382945
fast: false

382933
type: SpeciesReference
stoichiometry: 1.0
species: 283830

382958
type: SpeciesReference
stoichiometry: 1.0
species: 285529

285529
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_octadecanoate__n_C180__C18H35O2

382994
type: SpeciesReference
stoichiometry: 1.0
species: 286099

297527
type: LocalParameter
value: 0.0

297525
type: LocalParameter
value: 8.06E-4

297524
type: LocalParameter
value: 0.0

297523
type: LocalParameter
value: 999999.0

297521
type: LocalParameter
value: -999999.0

382970
type: SpeciesReference
stoichiometry: 1.0
species: 283713

283713
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_AMP_C10H12N5O7P

382982
type: SpeciesReference
stoichiometry: 1.0
species: 285796

285796
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Diphosphate_HO7P2

382945
type: SpeciesReference
stoichiometry: 1.0
species: 284013

289658
type: Reaction
kinetic law: 404252
product: 404240
reactant: 404228
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_indole_3_acetate_mitochondrial_transport_via_diffusion

299521
type: LocalParameter
value: 0.0

299519
type: LocalParameter
value: 0.0

299518
type: LocalParameter
value: 0.0

299516
type: LocalParameter
value: 999999.0

299515
type: LocalParameter
value: -999999.0

404240
type: SpeciesReference
stoichiometry: 1.0
species: 285035

285035
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Indole_3_acetate_C10H8NO2

404228
type: SpeciesReference
stoichiometry: 1.0
species: 285032

285032
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Indole_3_acetate_C10H8NO2

289672
type: Reaction
name: R_inositol_phosphorylceramide__ceramide_1__24C__phospholipase_C
product: 404625
notes: GENE_ASSOCIATION: YER019W PROTEIN_ASSOCIATION: Isc1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
product: 404637
reversible: false
fast: false
kinetic law: 404662
reactant: 404599
product: 404649
reactant: 404612

404625
type: SpeciesReference
stoichiometry: 1.0
species: 283902

283902
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_1__Sphinganinen_C240__C42H85NO3

404637
type: SpeciesReference
stoichiometry: 1.0
species: 284787

299570
type: LocalParameter
value: -0.023758

299568
type: LocalParameter
value: 0.0

299567
type: LocalParameter
value: 0.0

299565
type: LocalParameter
value: 999999.0

299564
type: LocalParameter
value: 0.0

404599
type: SpeciesReference
stoichiometry: 1.0
species: 284757

404649
type: SpeciesReference
stoichiometry: 1.0
species: 285309

404612
type: SpeciesReference
stoichiometry: 0.01
species: 285065

285065
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

287305
type: Reaction
kinetic law: 348602
product: 348590
reactant: 348578
notes: GENE_ASSOCIATION: YEL058W PROTEIN_ASSOCIATION: Pcm1 SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 5.4.2.3
fast: false
reversible: true
name: R_phosphoacetylglucosamine_mutase

291656
type: LocalParameter
value: 0.0

291654
type: LocalParameter
value: 0.0

291652
type: LocalParameter
value: 0.0

291650
type: LocalParameter
value: 999999.0

291648
type: LocalParameter
value: -999999.0

348590
type: SpeciesReference
stoichiometry: 1.0
species: 283545

283545
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N_Acetyl_D_glucosamine_1_phosphate_C8H14NO9P

348578
type: SpeciesReference
stoichiometry: 1.0
species: 283548

283548
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N_Acetyl_D_glucosamine_6_phosphate_C8H14NO9P

284346
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Epimelibiose_C12H22O11

290446
type: Reaction
fast: false
reactant: 429826
notes: GENE_ASSOCIATION: YHR037W PROTEIN_ASSOCIATION: Put2-m SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 1.5.1.12
reactant: 429814
kinetic law: 429886
product: 429850
reactant: 429838
product: 429862
product: 429874
name: R_D1_pyrroline_5_carboxylate_dehydrogenase__mitochondrial
reversible: false

429826
type: SpeciesReference
stoichiometry: 1.0
species: 284766

429814
type: SpeciesReference
stoichiometry: 1.0
species: 284615

284615
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Glutamate_5_semialdehyde_C5H9NO3

302613
type: LocalParameter
value: -0.014849

302611
type: LocalParameter
value: 0.0

302610
type: LocalParameter
value: 0.0

302608
type: LocalParameter
value: 999999.0

302607
type: LocalParameter
value: 0.0

429850
type: SpeciesReference
stoichiometry: 1.0
species: 284624

284624
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Glutamate_C5H8NO4

429838
type: SpeciesReference
stoichiometry: 1.0
species: 285427

285427
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

429862
type: SpeciesReference
stoichiometry: 2.0
species: 284796

429874
type: SpeciesReference
stoichiometry: 1.0
species: 285439

285439
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

290558
type: Reaction
product: 433515
product: 433540
product: 433552
kinetic law: 433564
fast: false
name: R_O_succinylhomoserine_lyase__elimination___reversible
product: 433527
reactant: 433491
reactant: 433503
notes: GENE_ASSOCIATION: YML082W PROTEIN_ASSOCIATION: Cgs1 SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 4.2.99.9
reversible: true

433515
type: SpeciesReference
stoichiometry: 1.0
species: 283074

283074
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Oxobutanoate_C4H5O3

433540
type: SpeciesReference
stoichiometry: 1.0
species: 285454

285454
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ammonium_H4N

433552
type: SpeciesReference
stoichiometry: 1.0
species: 286105

286105
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Succinate_C4H4O4

303005
type: LocalParameter
value: 0.0

303003
type: LocalParameter
value: 0.0

303002
type: LocalParameter
value: 0.0

303000
type: LocalParameter
value: 999999.0

302999
type: LocalParameter
value: -999999.0

433527
type: SpeciesReference
stoichiometry: 1.0
species: 284787

433491
type: SpeciesReference
stoichiometry: 1.0
species: 284757

433503
type: SpeciesReference
stoichiometry: 1.0
species: 286117

286117
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_O_Succinyl_L_homoserine_C8H12NO6

285766
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Phosphate_HO4P

284385
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ethanolamine_phosphate_C2H7NO4P

283569
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_O_Acetylcarnitine_C9H17NO4

286432
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Tyrosyl_tRNA_Tyr__C9H10NO2R

288430
type: Reaction
name: R_episterol_ester_hydrolase__yeast_specific
reactant: 373063
fast: false
product: 373171
product: 373087
product: 373111
kinetic law: 373183
product: 373123
reactant: 373075
product: 373135
product: 373147
reversible: false
notes: GENE_ASSOCIATION: ( YLL012W or YKL140W ) PROTEIN_ASSOCIATION: ( Yeh1 ) or ( Tgl1 ) SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS:
product: 373159
product: 373099

373063
type: SpeciesReference
stoichiometry: 0.01
species: 284340

373171
type: SpeciesReference
stoichiometry: 0.015
species: 286402

286402
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_tetradecanoate__n_C140__C14H27O2

373087
type: SpeciesReference
stoichiometry: 0.01
species: 284334

373111
type: SpeciesReference
stoichiometry: 0.02
species: 284828

284828
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Hexadecanoate__n_C160__C16H31O2

295627
type: LocalParameter
value: -0.024958

295624
type: LocalParameter
value: 0.0

295621
type: LocalParameter
value: 0.0

295618
type: LocalParameter
value: 999999.0

295615
type: LocalParameter
value: 0.0

373123
type: SpeciesReference
stoichiometry: 0.655
species: 284837

284837
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Hexadecenoate__n_C161__C16H29O2

373075
type: SpeciesReference
stoichiometry: 1.0
species: 284757

373135
type: SpeciesReference
stoichiometry: 0.01
species: 284867

284867
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_hexacosanoate__n_C260__C26H51O2

373147
type: SpeciesReference
stoichiometry: 0.03
species: 285529

373159
type: SpeciesReference
stoichiometry: 0.27
species: 285538

285538
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_octadecenoate__n_C181__C18H33O2

373099
type: SpeciesReference
stoichiometry: 1.0
species: 284787

287995
type: Reaction
kinetic law: 364014
product: 364002
product: 363990
reactant: 363978
notes: GENE_ASSOCIATION: YGL148W PROTEIN_ASSOCIATION: Aro2 SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.3.5
fast: false
reversible: false
name: R_chorismate_synthase

293783
type: LocalParameter
value: 0.0

293781
type: LocalParameter
value: 0.076083

293779
type: LocalParameter
value: 0.0

293777
type: LocalParameter
value: 999999.0

293774
type: LocalParameter
value: 0.0

364002
type: SpeciesReference
stoichiometry: 1.0
species: 285751

363990
type: SpeciesReference
stoichiometry: 1.0
species: 283959

283959
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_chorismate_C10H8O6

363978
type: SpeciesReference
stoichiometry: 1.0
species: 283239

283239
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_O__1_Carboxyvinyl__3_phosphoshikimate_C10H9O10P

289311
type: Reaction
reactant: 393331
name: R_glycine_cleavage_complex__lipoamide___mitochondrial
reactant: 393343
product: 393356
product: 393381
product: 393369
fast: false
reversible: true
kinetic law: 393393
notes: GENE_ASSOCIATION: ( YDR019C and YMR189W and YAL044C and YFL018C ) PROTEIN_ASSOCIATION: ( Gcv1-m and Gcv2-m and Gcv3-m and PdE3-m ) SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 1.8.1.4

393331
type: SpeciesReference
stoichiometry: 1.0
species: 284208

393343
type: SpeciesReference
stoichiometry: 1.0
species: 285399

393356
type: SpeciesReference
stoichiometry: 1.0
species: 284796

393381
type: SpeciesReference
stoichiometry: 1.0
species: 285412

393369
type: SpeciesReference
stoichiometry: 1.0
species: 285162

285162
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Lipoamide_C8H15NOS2

298337
type: LocalParameter
value: 0.0

298336
type: LocalParameter
value: 0.221001

298334
type: LocalParameter
value: 0.0

298333
type: LocalParameter
value: 999999.0

298332
type: LocalParameter
value: -999999.0

285363
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_S_Methyl_L_methionine_C6H14NO2S

286348
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_tRNA_Thr__R

286702
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_dTTP_C10H13N2O14P3

285279
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Methionyl_tRNA__Met__C5H10NOSR

287394
type: Reaction
reactant: 350340
fast: false
reactant: 350352
product: 350376
notes: GENE_ASSOCIATION: YCR032W PROTEIN_ASSOCIATION: Bph1 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
kinetic law: 350388
reversible: true
product: 350364
name: R_acetate_reversible_transport_via_proton_symport

350340
type: SpeciesReference
stoichiometry: 1.0
species: 283500

283500
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Acetate_C2H3O2

350352
type: SpeciesReference
stoichiometry: 1.0
species: 284790

350376
type: SpeciesReference
stoichiometry: 1.0
species: 284787

291916
type: LocalParameter
value: 0.0

291914
type: LocalParameter
value: -1.506442

291912
type: LocalParameter
value: 0.0

291910
type: LocalParameter
value: 999999.0

291908
type: LocalParameter
value: -999999.0

350364
type: SpeciesReference
stoichiometry: 1.0
species: 283497

283497
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Acetate_C2H3O2

289263
type: Reaction
product: 391737
name: R_glutamate_5_semialdehyde_dehydrogenase
fast: false
product: 391761
kinetic law: 391773
reversible: false
notes: GENE_ASSOCIATION: YOR323C PROTEIN_ASSOCIATION: Pro2 SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.2.1.41
product: 391749
reactant: 391701
reactant: 391713
reactant: 391725

391737
type: SpeciesReference
stoichiometry: 1.0
species: 284612

284612
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Glutamate_5_semialdehyde_C5H9NO3

391761
type: SpeciesReference
stoichiometry: 1.0
species: 285751

298181
type: LocalParameter
value: -0.004158

298180
type: LocalParameter
value: 0.0

298178
type: LocalParameter
value: 0.0

298177
type: LocalParameter
value: 999999.0

298176
type: LocalParameter
value: 0.0

391749
type: SpeciesReference
stoichiometry: 1.0
species: 285421

391701
type: SpeciesReference
stoichiometry: 1.0
species: 284609

284609
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Glutamate_5_phosphate_C5H8NO7P

391713
type: SpeciesReference
stoichiometry: 1.0
species: 284787

391725
type: SpeciesReference
stoichiometry: 1.0
species: 285436

284684
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_glycogen_C6H10O5

282888
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

288421
type: Reaction
kinetic law: 372883
product: 372871
product: 372859
reactant: 372847
notes: GENE_ASSOCIATION: ( YPL281C or YGR254W or YHR174W or YOR393W or YMR323W ) PROTEIN_ASSOCIATION: ( Err2 ) or ( Eno1 ) or ( Eno2 ) or ( Err1 ) or ( Err3 ) SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 4.2.1.11
fast: false
reversible: true
name: R_enolase

295588
type: LocalParameter
value: 0.0

295585
type: LocalParameter
value: 17.874156

295582
type: LocalParameter
value: 0.0

295579
type: LocalParameter
value: 999999.0

295576
type: LocalParameter
value: -999999.0

372871
type: SpeciesReference
stoichiometry: 1.0
species: 285700

285700
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Phosphoenolpyruvate_C3H2O6P

372859
type: SpeciesReference
stoichiometry: 1.0
species: 284757

372847
type: SpeciesReference
stoichiometry: 1.0
species: 283086

283086
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Glycerate_2_phosphate_C3H4O7P

283512
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Acetaldehyde_C2H4O

290562
type: Reaction
kinetic law: 433710
product: 433698
product: 433674
reversible: false
name: R_sphingolipid_long_chain_base_kinase__phytosphingosine_
reactant: 433649
product: 433686
notes: GENE_ASSOCIATION: ( YOR171C or YLR260W ) PROTEIN_ASSOCIATION: ( Lcb4 ) or ( Lcb5 ) SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
fast: false
reactant: 433662

303019
type: LocalParameter
value: -0.044942

303017
type: LocalParameter
value: 0.0

303016
type: LocalParameter
value: 0.0

303014
type: LocalParameter
value: 999999.0

303013
type: LocalParameter
value: 0.0

433698
type: SpeciesReference
stoichiometry: 1.0
species: 285877

285877
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Phytosphingosine_1_phosphate_C18H39NO6P

433674
type: SpeciesReference
stoichiometry: 1.0
species: 283602

433649
type: SpeciesReference
stoichiometry: 1.0
species: 283830

433686
type: SpeciesReference
stoichiometry: 1.0
species: 284787

433662
type: SpeciesReference
stoichiometry: 1.0
species: 285883

285883
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Phytosphingosine_C18H40NO3

290214
type: Reaction
product: 422020
kinetic law: 422044
product: 422032
fast: false
reactant: 421996
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Phospholipid_Biosynthesis PROTEIN_CLASS: 3.1.3.27
name: R_phosphatidylglycerol_phosphate_phosphatase_A__yeast_specific__mitochondrial
reactant: 422008
reversible: false

422020
type: SpeciesReference
stoichiometry: 0.01
species: 285712

285712
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

301775
type: LocalParameter
value: -0.712984

301774
type: LocalParameter
value: 0.0

301771
type: LocalParameter
value: 0.0

301770
type: LocalParameter
value: 999999.0

301767
type: LocalParameter
value: 0.0

422032
type: SpeciesReference
stoichiometry: 1.0
species: 285760

285760
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Phosphate_HO4P

421996
type: SpeciesReference
stoichiometry: 1.0
species: 284766

422008
type: SpeciesReference
stoichiometry: 0.01
species: 285715

285715
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

288370
type: Reaction
product: 372001
reversible: false
kinetic law: 372013
reactant: 371977
reactant: 371965
name: R_D_lactate_dehydrogenase__cytosolicmitochondrial
fast: false
product: 371989
notes: GENE_ASSOCIATION: ( ( YJR048W and YDL174C ) or ( YEL039C and YDL174C ) or ( YJR048W and YEL071W ) or ( YEL039C and YEL071W ) ) PROTEIN_ASSOCIATION: ( Cyc1-m and Dld1-m ) or ( Cyc7-m and Dld1-m ) or ( Cyc1-m and Dld3 ) or ( Cyc7-m and Dld3 ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.2.4

372001
type: SpeciesReference
stoichiometry: 2.0
species: 284463

284463
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Ferrocytochrome_c_C42H53FeN8O6S2

295367
type: LocalParameter
value: -0.004455

295364
type: LocalParameter
value: 0.0

295361
type: LocalParameter
value: 0.0

295358
type: LocalParameter
value: 999999.0

295355
type: LocalParameter
value: 0.0

371977
type: SpeciesReference
stoichiometry: 2.0
species: 284445

284445
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Ferricytochrome_c_C42H52FeN8O6S2

371965
type: SpeciesReference
stoichiometry: 1.0
species: 285107

371989
type: SpeciesReference
stoichiometry: 1.0
species: 285943

285943
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Pyruvate_C3H3O3

288533
type: Reaction
kinetic law: 374958
product: 374946
reactant: 374934
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Adenine_exchange

296036
type: LocalParameter
value: -0.122155

296034
type: LocalParameter
value: 0.0

296033
type: LocalParameter
value: 0.0

296032
type: LocalParameter
value: 999999.0

296030
type: LocalParameter
value: 0.0

374946
type: SpeciesReference
stoichiometry: 1.0
species: 286618

286618
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Adenine_C5H5N5

374934
type: SpeciesReference
stoichiometry: 1.0
species: 283587

287509
type: Reaction
kinetic law: 352814
reversible: true
name: R_alpha_ketoglutaratemalate_transporter
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reactant: 352766
product: 352790
reactant: 352778
product: 352802

292270
type: LocalParameter
value: 0.0

292268
type: LocalParameter
value: 0.0

292266
type: LocalParameter
value: 0.0

292264
type: LocalParameter
value: 999999.0

292262
type: LocalParameter
value: -999999.0

352766
type: SpeciesReference
stoichiometry: 1.0
species: 283641

283641
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Oxoglutarate_C5H4O5

352790
type: SpeciesReference
stoichiometry: 1.0
species: 285207

285207
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Malate_C4H4O5

352778
type: SpeciesReference
stoichiometry: 1.0
species: 285210

285210
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Malate_C4H4O5

352802
type: SpeciesReference
stoichiometry: 1.0
species: 283644

283644
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_2_Oxoglutarate_C5H4O5

288668
type: Reaction
kinetic law: 376590
product: 376578
reactant: 376565
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_Galactose_exchange

296402
type: LocalParameter
value: -0.023758

296400
type: LocalParameter
value: 0.0

296399
type: LocalParameter
value: 0.0

296398
type: LocalParameter
value: 999999.0

296396
type: LocalParameter
value: 0.0

376578
type: SpeciesReference
stoichiometry: 1.0
species: 286753

286753
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Galactose_C6H12O6

376565
type: SpeciesReference
stoichiometry: 1.0
species: 284535

284535
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Galactose_C6H12O6

283995
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_CO2_CO2

286639
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Arabinose_C5H10O5

288079
type: Reaction
reactant: 365467
reactant: 365479
product: 365503
name: R_carnitine_O_aceyltransferase__mitochondrial
fast: false
notes: GENE_ASSOCIATION: YML042W PROTEIN_ASSOCIATION: Cat2-m SUBSYSTEM: S_Fatty_Acid_Metabolism PROTEIN_CLASS: 2.3.1.7
reversible: true
kinetic law: 365515
product: 365491

365467
type: SpeciesReference
stoichiometry: 1.0
species: 283569

365479
type: SpeciesReference
stoichiometry: 1.0
species: 284016

284016
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Coenzyme_A_C21H32N7O16P3S

365503
type: SpeciesReference
stoichiometry: 1.0
species: 284040

284040
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Carnitine_C7H15NO3

294106
type: LocalParameter
value: 0.0

294103
type: LocalParameter
value: 0.0

294100
type: LocalParameter
value: 0.0

294097
type: LocalParameter
value: 999999.0

294094
type: LocalParameter
value: -999999.0

365491
type: SpeciesReference
stoichiometry: 1.0
species: 283524

283524
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Acetyl_CoA_C23H34N7O17P3S

284811
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_Hydroxybutane_1_2_4_tricarboxylate_C7H7O7

284972
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_isobutyl_acetate_C6H12O2

283629
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_S_Adenosyl_L_homocysteine_C14H20N6O5S

283428
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_2_Aminoadipate_C6H10NO4

289437
type: Reaction
fast: false
kinetic law: 397500
notes: GENE_ASSOCIATION: YJL167W PROTEIN_ASSOCIATION: Erg20 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS: 2.5.1.10
product: 397476
name: R_geranyltranstransferase
product: 397488
reactant: 397464
reactant: 397452
reversible: false

298767
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value: 0.0

298766
type: LocalParameter
value: 0.001267

298764
type: LocalParameter
value: 0.0

298763
type: LocalParameter
value: 999999.0

298762
type: LocalParameter
value: 0.0

397476
type: SpeciesReference
stoichiometry: 1.0
species: 284481

284481
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Farnesyl_diphosphate_C15H25O7P2

397488
type: SpeciesReference
stoichiometry: 1.0
species: 285796

397464
type: SpeciesReference
stoichiometry: 1.0
species: 285083

285083
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Isopentenyl_diphosphate_C5H9O7P2

397452
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stoichiometry: 1.0
species: 284699

284699
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Geranyl_diphosphate_C10H17O7P2

288118
type: Reaction
reactant: 366501
notes: GENE_ASSOCIATION: YAL012W PROTEIN_ASSOCIATION: Cys3 SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 4.4.1.1
reversible: false
reactant: 366513
name: R_cystathionine_g_lyase
product: 366550
product: 366526
product: 366538
fast: false
kinetic law: 366562

366501
type: SpeciesReference
stoichiometry: 1.0
species: 284064

284064
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Cystathionine_C7H14N2O4S

366513
type: SpeciesReference
stoichiometry: 1.0
species: 284757

366550
type: SpeciesReference
stoichiometry: 1.0
species: 285454

366526
type: SpeciesReference
stoichiometry: 1.0
species: 283074

366538
type: SpeciesReference
stoichiometry: 1.0
species: 284058

284058
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Cysteine_C3H7NO2S

294275
type: LocalParameter
value: 0.0

294272
type: LocalParameter
value: 0.0019

294269
type: LocalParameter
value: 0.0

294266
type: LocalParameter
value: 999999.0

294263
type: LocalParameter
value: 0.0

289389
type: Reaction
reactant: 395915
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Nuclear PROTEIN_CLASS:
reversible: true
fast: false
product: 395939
name: R_glutamate_nuclear_transport_via_proton_symport
product: 395951
kinetic law: 395963
reactant: 395927

395915
type: SpeciesReference
stoichiometry: 1.0
species: 284618

395939
type: SpeciesReference
stoichiometry: 1.0
species: 284627

284627
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_L_Glutamate_C5H8NO4

395951
type: SpeciesReference
stoichiometry: 1.0
species: 284799

284799
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_H_H

298598
type: LocalParameter
value: 0.0

298596
type: LocalParameter
value: 0.0

298595
type: LocalParameter
value: 0.0

298593
type: LocalParameter
value: 999999.0

298592
type: LocalParameter
value: -999999.0

395927
type: SpeciesReference
stoichiometry: 1.0
species: 284787

286612
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Acetaldehyde_C2H4O

286147
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

290354
type: Reaction
name: R_phosphoribosylpyrophosphate_synthetase
reversible: true
product: 426968
reactant: 426956
kinetic law: 427004
fast: false
notes: GENE_ASSOCIATION: ( YER099C or YOL061W or YBL068W or YHL011C or YKL181W ) PROTEIN_ASSOCIATION: ( Prs2 ) or ( Prs5 ) or ( Prs4 ) or ( Prs3 ) or ( Prs1 ) SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 2.7.6.1
reactant: 426944
product: 426992
product: 426980

426968
type: SpeciesReference
stoichiometry: 1.0
species: 283713

426956
type: SpeciesReference
stoichiometry: 1.0
species: 285973

285973
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_alpha_D_Ribose_5_phosphate_C5H9O8P

302291
type: LocalParameter
value: 0.0

302289
type: LocalParameter
value: 0.087595

302288
type: LocalParameter
value: 0.0

302286
type: LocalParameter
value: 999999.0

302285
type: LocalParameter
value: -999999.0

426944
type: SpeciesReference
stoichiometry: 1.0
species: 283830

426992
type: SpeciesReference
stoichiometry: 1.0
species: 285853

285853
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_Phospho_alpha_D_ribose_1_diphosphate_C5H8O14P3

426980
type: SpeciesReference
stoichiometry: 1.0
species: 284787

290466
type: Reaction
reversible: false
notes: GENE_ASSOCIATION: YDR236C PROTEIN_ASSOCIATION: Fmn1 SUBSYSTEM: S_Riboflavin_Metabolism PROTEIN_CLASS: 2.7.1.26
product: 430432
product: 430457
product: 430445
kinetic law: 430469
reactant: 430420
name: R_riboflavin_kinase
fast: false
reactant: 430408

430432
type: SpeciesReference
stoichiometry: 1.0
species: 283602

430457
type: SpeciesReference
stoichiometry: 1.0
species: 284787

430445
type: SpeciesReference
stoichiometry: 1.0
species: 284451

284451
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_FMN_C17H19N4O9P

302683
type: LocalParameter
value: -0.28846

302681
type: LocalParameter
value: 0.0

302680
type: LocalParameter
value: 0.0

302678
type: LocalParameter
value: 999999.0

302677
type: LocalParameter
value: 0.0

430420
type: SpeciesReference
stoichiometry: 1.0
species: 285985

285985
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Riboflavin_C17H20N4O6

430408
type: SpeciesReference
stoichiometry: 1.0
species: 283830

288274
type: Reaction
notes: GENE_ASSOCIATION: YNL256W PROTEIN_ASSOCIATION: Fol1-m SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 2.5.1.15
name: R_dihydropteroate_synthase__mitochondrial
product: 369924
kinetic law: 369948
reactant: 369898
reversible: false
reactant: 369911
product: 369936
fast: false

369924
type: SpeciesReference
stoichiometry: 1.0
species: 284229

284229
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Dihydropteroate_C14H13N6O3

294951
type: LocalParameter
value: -0.035241

294948
type: LocalParameter
value: 0.0

294945
type: LocalParameter
value: 0.0

294942
type: LocalParameter
value: 999999.0

294939
type: LocalParameter
value: 0.0

369898
type: SpeciesReference
stoichiometry: 1.0
species: 282968

282968
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_Amino_4_hydroxy_6_hydroxymethyl_7_8_dihydropteridine_C7H9N5O2

369911
type: SpeciesReference
stoichiometry: 1.0
species: 283272

283272
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_4_Aminobenzoate_C7H6NO2

369936
type: SpeciesReference
stoichiometry: 1.0
species: 284766

289554
type: Reaction
product: 401000
product: 401012
fast: false
reactant: 400976
kinetic law: 401024
reactant: 400988
reversible: false
notes: GENE_ASSOCIATION: YFR025C PROTEIN_ASSOCIATION: His2 SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 3.1.3.15
name: R_histidinol_phosphatase

401000
type: SpeciesReference
stoichiometry: 1.0
species: 284912

284912
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Histidinol_C6H12N3O

401012
type: SpeciesReference
stoichiometry: 1.0
species: 285751

400976
type: SpeciesReference
stoichiometry: 1.0
species: 284757

299158
type: LocalParameter
value: 0.0

299157
type: LocalParameter
value: 0.019085

299155
type: LocalParameter
value: 0.0

299154
type: LocalParameter
value: 999999.0

299152
type: LocalParameter
value: 0.0

400988
type: SpeciesReference
stoichiometry: 1.0
species: 284909

284909
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Histidinol_phosphate_C6H11N3O4P

287146
type: Reaction
kinetic law: 345665
product: 345653
product: 345641
reactant: 345629
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Quinone_Biosynthesis PROTEIN_CLASS:
fast: false
reversible: false
name: R_3_Hexaprenyl_4_hydroxy_5_methoxybenzoate_decarboxylase__mitochondrial

291175
type: LocalParameter
value: 0.0

291173
type: LocalParameter
value: 0.0

291171
type: LocalParameter
value: 0.0

291169
type: LocalParameter
value: 999999.0

291167
type: LocalParameter
value: 0.0

345653
type: SpeciesReference
stoichiometry: 1.0
species: 284001

345641
type: SpeciesReference
stoichiometry: 1.0
species: 283020

283020
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_Hexaprenyl_6_methoxyphenol_C37H56O2

345629
type: SpeciesReference
stoichiometry: 1.0
species: 283170

283170
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_3_Hexaprenyl_4_hydroxy_5_methoxybenzoate_C38H55O4

283770
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_L_Arginine_C6H15N4O2

284079
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Deoxyadenosine_C10H13N5O3

285228
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Maltose_C12H22O11

287336
type: Reaction
name: R_acyl_CoA_oxidase__decanoyl_CoA___peroxisomal
notes: GENE_ASSOCIATION: YGL205W PROTEIN_ASSOCIATION: Pox1-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 1.3.3.6
product: 349204
product: 349192
fast: false
reactant: 349180
reactant: 349168
kinetic law: 349216
reversible: false

349204
type: SpeciesReference
stoichiometry: 1.0
species: 284754

349192
type: SpeciesReference
stoichiometry: 1.0
species: 284109

284109
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_trans_Dec_2_enoyl_CoA_C31H48N7O17P3S

349180
type: SpeciesReference
stoichiometry: 1.0
species: 285499

349168
type: SpeciesReference
stoichiometry: 1.0
species: 284127

284127
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

291737
type: LocalParameter
value: 0.0

291735
type: LocalParameter
value: 0.0

291733
type: LocalParameter
value: 0.0

291731
type: LocalParameter
value: 999999.0

291729
type: LocalParameter
value: 0.0

289205
type: Reaction
kinetic law: 389913
product: 389901
reactant: 389889
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_formate_transport_via_diffusion

297992
type: LocalParameter
value: 0.0

297991
type: LocalParameter
value: -0.001488

297990
type: LocalParameter
value: 0.0

297988
type: LocalParameter
value: 999999.0

297987
type: LocalParameter
value: -999999.0

389901
type: SpeciesReference
stoichiometry: 1.0
species: 284466

284466
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Formate_CH1O2

389889
type: SpeciesReference
stoichiometry: 1.0
species: 284469

284469
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Formate_CH1O2

286069
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Sphinganine_C18H40NO2

290616
type: Reaction
product: 435356
kinetic law: 435368
reversible: false
name: R_sucrose_transport_in_via_proton_symport
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
reactant: 435332
product: 435344
reactant: 435320
fast: false

435356
type: SpeciesReference
stoichiometry: 1.0
species: 286120

286120
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Sucrose_C12H22O11

303218
type: LocalParameter
value: -0.047516

303216
type: LocalParameter
value: 0.0

303215
type: LocalParameter
value: 0.0

303213
type: LocalParameter
value: 999999.0

303212
type: LocalParameter
value: 0.0

435332
type: SpeciesReference
stoichiometry: 1.0
species: 286123

286123
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Sucrose_C12H22O11

435344
type: SpeciesReference
stoichiometry: 1.0
species: 284787

435320
type: SpeciesReference
stoichiometry: 1.0
species: 284790

289688
type: Reaction
reactant: 405170
kinetic law: 405206
reactant: 405158
notes: GENE_ASSOCIATION: YKL004W PROTEIN_ASSOCIATION: Aur1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
product: 405182
fast: false
reversible: false
name: R_Inositol_phosphorylceramide_synthase__ceramide_2__24C___yeast_specific
product: 405194

405170
type: SpeciesReference
stoichiometry: 0.01
species: 285898

285898
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

299628
type: LocalParameter
value: 0.0

299626
type: LocalParameter
value: 0.0

299625
type: LocalParameter
value: 0.0

299622
type: LocalParameter
value: 999999.0

299621
type: LocalParameter
value: 0.0

405158
type: SpeciesReference
stoichiometry: 1.0
species: 283914

283914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_2__Phytosphingosinen_C240__C42H85NO4

405182
type: SpeciesReference
stoichiometry: 0.01
species: 282893

405194
type: SpeciesReference
stoichiometry: 0.01
species: 285071

285071
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

283686
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Allantoate_C4H7N4O4

284490
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Fructose_C6H12O6

290820
type: Reaction
reactant: 442147
fast: false
reversible: true
kinetic law: 442183
name: R_L_valine_reversible_transport_via_proton_symport
notes: GENE_ASSOCIATION: ( YKR039W or YCL025C or YDR046C or YBR069C or YBR068C ) PROTEIN_ASSOCIATION: ( Gap1 ) or ( Agp1 ) or ( Bap3 ) or ( Tat1 ) or ( Bap2 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
product: 442171
product: 442159
reactant: 442134

442147
type: SpeciesReference
stoichiometry: 1.0
species: 286498

286498
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Valine_C5H11NO2

303932
type: LocalParameter
value: 0.0

303931
type: LocalParameter
value: 0.0

303929
type: LocalParameter
value: 0.0

303928
type: LocalParameter
value: 999999.0

303926
type: LocalParameter
value: -999999.0

442171
type: SpeciesReference
stoichiometry: 1.0
species: 286495

286495
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Valine_C5H11NO2

442159
type: SpeciesReference
stoichiometry: 1.0
species: 284787

442134
type: SpeciesReference
stoichiometry: 1.0
species: 284790

284921
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Hydroxymethylbilane_C40H38N4O17

283113
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3__5__Cyclic_dAMP_C10H11N5O5P

290470
type: Reaction
product: 430602
fast: false
reversible: false
reactant: 430566
notes: GENE_ASSOCIATION: YOL143C PROTEIN_ASSOCIATION: Rib4 SUBSYSTEM: S_Riboflavin_Metabolism PROTEIN_CLASS: 2.5.1.9
product: 430578
reactant: 430553
product: 430590
name: R_riboflavin_synthase
kinetic law: 430614

430602
type: SpeciesReference
stoichiometry: 1.0
species: 285751

430566
type: SpeciesReference
stoichiometry: 1.0
species: 284106

284106
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3_4_dihydroxy_2_butanone_4_phosphate_C4H7O6P

430578
type: SpeciesReference
stoichiometry: 1.0
species: 284241

284241
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_6_7_Dimethyl_8__1_D_ribityl_lumazine_C13H18N4O6

430553
type: SpeciesReference
stoichiometry: 1.0
species: 283356

430590
type: SpeciesReference
stoichiometry: 2.0
species: 284757

302697
type: LocalParameter
value: 0.0

302695
type: LocalParameter
value: 5.7E-4

302694
type: LocalParameter
value: 0.0

302692
type: LocalParameter
value: 999999.0

302691
type: LocalParameter
value: 0.0

282932
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_1_Pyrroline_3_hydroxy_5_carboxylate_C5H6NO3

285763
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_Phosphate_HO4P

289616
type: Reaction
kinetic law: 402956
product: 402944
reactant: 402932
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_isobutyl_alcohol_transport__mitochondrial_

299374
type: LocalParameter
value: 0.0

299372
type: LocalParameter
value: 0.0

299371
type: LocalParameter
value: 0.0

299369
type: LocalParameter
value: 999999.0

299368
type: LocalParameter
value: -999999.0

402944
type: SpeciesReference
stoichiometry: 1.0
species: 284981

284981
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_isobutyl_alcohol_C4H10O

402932
type: SpeciesReference
stoichiometry: 1.0
species: 284975

284975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_isobutyl_alcohol_C4H10O

286693
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Dodecanoate__n_C120__C12H23O2

285790
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Propanoyl_CoA_C24H36N7O17P3S

289630
type: Reaction
kinetic law: 403368
product: 403356
reactant: 403344
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_indole_3_acetaldehyde_mitochondrial_transport_via_diffusion

299423
type: LocalParameter
value: 0.0

299421
type: LocalParameter
value: 0.0

299420
type: LocalParameter
value: 0.0

299418
type: LocalParameter
value: 999999.0

299417
type: LocalParameter
value: -999999.0

403356
type: SpeciesReference
stoichiometry: 1.0
species: 284999

284999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Indole_3_acetaldehyde_C10H9NO

403344
type: SpeciesReference
stoichiometry: 1.0
species: 284993

284669
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Glycerol_3_phosphate_C3H7O6P

289453
type: Reaction
product: 397974
reactant: 397949
fast: false
product: 397986
notes: GENE_ASSOCIATION: YPL059W PROTEIN_ASSOCIATION: Grx5-m SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 1.11.1.9
reactant: 397961
kinetic law: 397998
reversible: true
name: R_glutathione_peroxidase__mitochondria

397974
type: SpeciesReference
stoichiometry: 1.0
species: 284717

284717
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Oxidized_glutathione_C20H30N6O12S2

397949
type: SpeciesReference
stoichiometry: 2.0
species: 284726

284726
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Reduced_glutathione_C10H16N3O6S

397986
type: SpeciesReference
stoichiometry: 2.0
species: 284766

397961
type: SpeciesReference
stoichiometry: 1.0
species: 284750

284750
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Hydrogen_peroxide_H2O2

298821
type: LocalParameter
value: 0.0

298820
type: LocalParameter
value: 0.0

298818
type: LocalParameter
value: 0.0

298817
type: LocalParameter
value: 999999.0

298816
type: LocalParameter
value: -999999.0

287842
type: Reaction
reversible: true
kinetic law: 360427
name: R__R_R__butanediol_dehydrogenase
reactant: 360367
product: 360403
reactant: 360379
product: 360415
notes: GENE_ASSOCIATION: YAL060W PROTEIN_ASSOCIATION: Bdh1 SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.4
product: 360391
fast: false

293282
type: LocalParameter
value: 0.0

293280
type: LocalParameter
value: 0.0

293278
type: LocalParameter
value: 0.0

293276
type: LocalParameter
value: 999999.0

293274
type: LocalParameter
value: -999999.0

360367
type: SpeciesReference
stoichiometry: 1.0
species: 283854

283854
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M__R_R__2_3_Butanediol_C4H10O2

360403
type: SpeciesReference
stoichiometry: 1.0
species: 284787

360379
type: SpeciesReference
stoichiometry: 1.0
species: 285396

285396
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

360415
type: SpeciesReference
stoichiometry: 1.0
species: 285409

285409
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

360391
type: SpeciesReference
stoichiometry: 1.0
species: 283578

283578
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M__R__Acetoin_C4H8O2

285784
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M__R__Pantothenate_C9H16NO5

290404
type: Reaction
product: 428483
product: 428471
reversible: false
name: R_pantetheine_phosphate_adenylyltransferase
reactant: 428447
reactant: 428435
reactant: 428459
fast: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 2.7.7.3
kinetic law: 428495

428483
type: SpeciesReference
stoichiometry: 1.0
species: 285796

428471
type: SpeciesReference
stoichiometry: 1.0
species: 284268

428447
type: SpeciesReference
stoichiometry: 1.0
species: 284787

428435
type: SpeciesReference
stoichiometry: 1.0
species: 283830

428459
type: SpeciesReference
stoichiometry: 1.0
species: 285640

302466
type: LocalParameter
value: -0.041576

302464
type: LocalParameter
value: 0.0

302463
type: LocalParameter
value: 0.0

302461
type: LocalParameter
value: 999999.0

302460
type: LocalParameter
value: 0.0

284343
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870

283212
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_3_Oxododecanoyl_CoA_C33H52N7O18P3S

286882
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Sodium_Na

286516
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Xanthosine_5__phosphate_C10H11N4O9P

289018
type: Reaction
kinetic law: 381211
product: 381199
reactant: 381187
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acyl_ACP_mitochondrial_transport

297328
type: LocalParameter
value: 0.0

297327
type: LocalParameter
value: 0.0

297326
type: LocalParameter
value: 0.0

297324
type: LocalParameter
value: 999999.0

297323
type: LocalParameter
value: 0.0

381199
type: SpeciesReference
stoichiometry: 1.0
species: 284855

284855
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

381187
type: SpeciesReference
stoichiometry: 1.0
species: 284858

284858
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

284259
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Dolichyl_phosphate_D_mannose_C21H38O9P

287539
type: Reaction
kinetic law: 353429
product: 353417
reactant: 353405
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_Alanine_transport_from_mitochondia_to_cytoplasm

292361
type: LocalParameter
value: -0.00297

292358
type: LocalParameter
value: 0.0

292356
type: LocalParameter
value: 0.0

292354
type: LocalParameter
value: 999999.0

292352
type: LocalParameter
value: 0.0

353417
type: SpeciesReference
stoichiometry: 1.0
species: 283659

283659
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Alanine_C3H7NO2

353405
type: SpeciesReference
stoichiometry: 1.0
species: 283665

283665
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Alanine_C3H7NO2

289570
type: Reaction
reactant: 401529
product: 401553
fast: false
reactant: 401505
reversible: true
product: 401565
product: 401541
name: R_Hydroxymethylglutaryl_CoA_reductase
kinetic law: 401577
notes: GENE_ASSOCIATION: ( YLR450W or YML075C ) PROTEIN_ASSOCIATION: ( Hmg2 ) or ( Hmg1 ) SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS: 1.1.1.34
reactant: 401517

401529
type: SpeciesReference
stoichiometry: 2.0
species: 285421

401553
type: SpeciesReference
stoichiometry: 1.0
species: 284924

284924
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

401505
type: SpeciesReference
stoichiometry: 1.0
species: 284013

401565
type: SpeciesReference
stoichiometry: 2.0
species: 285436

401541
type: SpeciesReference
stoichiometry: 2.0
species: 284787

299213
type: LocalParameter
value: 0.0

299212
type: LocalParameter
value: -0.0038

299210
type: LocalParameter
value: 0.0

299209
type: LocalParameter
value: 999999.0

299207
type: LocalParameter
value: -999999.0

401517
type: SpeciesReference
stoichiometry: 1.0
species: 285285

285285
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M__R__Mevalonate_C6H11O4

286345
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_tRNA_Ser__R

286636
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_S_Adenosyl_L_methionine_C15H23N6O5S

285442
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873

285237
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Mannose_6_phosphate_C6H11O9P

290656
type: Reaction
kinetic law: 436760
product: 436748
product: 436736
reactant: 436724
notes: GENE_ASSOCIATION: YEL046C PROTEIN_ASSOCIATION: Gly1 SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.1.2.5
fast: false
reversible: false
name: R_L_allo_Threonine_Aldolase

303358
type: LocalParameter
value: -0.023758

303356
type: LocalParameter
value: 0.0

303355
type: LocalParameter
value: 0.0

303353
type: LocalParameter
value: 999999.0

303352
type: LocalParameter
value: 0.0

436748
type: SpeciesReference
stoichiometry: 1.0
species: 284657

284657
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Glycine_C2H5NO2

436736
type: SpeciesReference
stoichiometry: 1.0
species: 283512

436724
type: SpeciesReference
stoichiometry: 1.0
species: 283827

283827
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Allo_threonine_C4H9NO3

288626
type: Reaction
kinetic law: 376080
product: 376068
reactant: 376056
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_episterol_ester__yeast_specific_exchange

296290
type: LocalParameter
value: -32.49596

296288
type: LocalParameter
value: 0.0

296287
type: LocalParameter
value: 0.0

296286
type: LocalParameter
value: 999999.0

296284
type: LocalParameter
value: 0.0

376068
type: SpeciesReference
stoichiometry: 1.0
species: 286711

286711
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870

376056
type: SpeciesReference
stoichiometry: 1.0
species: 284343

290496
type: Reaction
notes: GENE_ASSOCIATION: ( ( ( YER070W and YGR180C ) and YLR043C ) or ( ( YER070W and YGR180C ) and YGR209C ) ) PROTEIN_ASSOCIATION: ( Rnr14-n and Trx1 ) or ( Rnr14-n and Trx2 ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 1.17.4.1
product: 431460
reversible: false
product: 431436
product: 431448
fast: false
reactant: 431411
kinetic law: 431472
reactant: 431424
name: R_ribonucleoside_diphosphate_reductase__UDP___nuclear

431460
type: SpeciesReference
stoichiometry: 1.0
species: 286237

286237
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_Oxidized_thioredoxin_X

431436
type: SpeciesReference
stoichiometry: 1.0
species: 284298

284298
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_dUDP_C9H11N2O11P2

431448
type: SpeciesReference
stoichiometry: 1.0
species: 284769

284769
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_H2O_H2O

431411
type: SpeciesReference
stoichiometry: 1.0
species: 286249

286249
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_Reduced_thioredoxin_XH2

302788
type: LocalParameter
value: -0.17759

302786
type: LocalParameter
value: 0.0

302785
type: LocalParameter
value: 0.0

302783
type: LocalParameter
value: 999999.0

302782
type: LocalParameter
value: 0.0

431424
type: SpeciesReference
stoichiometry: 1.0
species: 286441

286441
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_UDP_C9H11N2O12P2

283929
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_2___Sphinganinen_C260OH__C44H89NO4

290360
type: Reaction
reactant: 427113
reversible: false
kinetic law: 427161
product: 427149
reactant: 427125
product: 427137
notes: GENE_ASSOCIATION: YGR170W PROTEIN_ASSOCIATION: Psd2-g SUBSYSTEM: S_Phospholipid_Biosynthesis PROTEIN_CLASS: 4.1.1.65
fast: false
name: R_phosphatidylserine_decarboxylase__yeast_specific__Golgi

427113
type: SpeciesReference
stoichiometry: 1.0
species: 284793

284793
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282876
name: M_H_H

302312
type: LocalParameter
value: -0.00297

302310
type: LocalParameter
value: 0.0

302309
type: LocalParameter
value: 0.0

302307
type: LocalParameter
value: 999999.0

302306
type: LocalParameter
value: 0.0

427149
type: SpeciesReference
stoichiometry: 0.01
species: 285682

285682
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282876

427125
type: SpeciesReference
stoichiometry: 0.01
species: 285862

285862
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282876

427137
type: SpeciesReference
stoichiometry: 1.0
species: 283998

283998
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282876
name: M_CO2_CO2

285628
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Phenylacetaldehyde_C8H8O

288043
type: Reaction
kinetic law: 364875
product: 364862
reactant: 364850
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: true
name: R_CO2_peroxisomal_transport

293951
type: LocalParameter
value: 0.0

293948
type: LocalParameter
value: 0.0

293945
type: LocalParameter
value: 0.0

293944
type: LocalParameter
value: 999999.0

293943
type: LocalParameter
value: -999999.0

364862
type: SpeciesReference
stoichiometry: 1.0
species: 284010

284010
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_CO2_CO2

364850
type: SpeciesReference
stoichiometry: 1.0
species: 283992

289361
type: Reaction
fast: false
product: 394877
reactant: 394865
name: R_L_glutamine_transport_in_via_proton_antiport__vacuolar_
product: 394890
notes: GENE_ASSOCIATION: YJR001W PROTEIN_ASSOCIATION: Avt1-v SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
kinetic law: 394902
reversible: false
reactant: 394853

394877
type: SpeciesReference
stoichiometry: 1.0
species: 284787

394865
type: SpeciesReference
stoichiometry: 1.0
species: 284805

284805
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_H_H

394890
type: SpeciesReference
stoichiometry: 1.0
species: 284602

284602
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_L_Glutamine_C5H10N2O3

298503
type: LocalParameter
value: 0.0

298502
type: LocalParameter
value: 0.0

298500
type: LocalParameter
value: 0.0

298499
type: LocalParameter
value: 999999.0

298498
type: LocalParameter
value: 0.0

394853
type: SpeciesReference
stoichiometry: 1.0
species: 284595

284076
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Cytidine_C9H13N3O5

290660
type: Reaction
kinetic law: 436857
product: 436845
product: 436833
reactant: 436821
notes: GENE_ASSOCIATION: ( YCL064C or YKL218C ) PROTEIN_ASSOCIATION: ( Cha1 ) or ( Sry1 ) SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.3.1.19
fast: false
reversible: false
name: R_L_threonine_deaminase

303372
type: LocalParameter
value: 0.0

303370
type: LocalParameter
value: 0.053572

303369
type: LocalParameter
value: 0.0

303367
type: LocalParameter
value: 999999.0

303366
type: LocalParameter
value: 0.0

436845
type: SpeciesReference
stoichiometry: 1.0
species: 285454

436833
type: SpeciesReference
stoichiometry: 1.0
species: 283074

436821
type: SpeciesReference
stoichiometry: 1.0
species: 286204

286204
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Threonine_C4H9NO3

289109
type: Reaction
reactant: 385195
product: 385244
reactant: 385208
product: 385268
notes: GENE_ASSOCIATION: ( YKL192C and YER061C and YHR067W and YOR221C and YBR026C and YKL055C ) PROTEIN_ASSOCIATION: ( Acp1-m and Cem1-m and Htd2-m and Mct1-m and Mrf1-m and Oar1-m ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS:
product: 385220
reactant: 385171
product: 385232
kinetic law: 385280
fast: false
reactant: 385183
name: R_fatty_acyl_ACP_synthase__n_C100ACP___mitochondrial
reversible: false
product: 385256

385195
type: SpeciesReference
stoichiometry: 2.0
species: 285439

385244
type: SpeciesReference
stoichiometry: 1.0
species: 284112

284112
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

385208
type: SpeciesReference
stoichiometry: 1.0
species: 285514

285514
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Octanoyl_ACP__n_C80ACP__C19H35N2O8PRS

385268
type: SpeciesReference
stoichiometry: 2.0
species: 285427

385220
type: SpeciesReference
stoichiometry: 1.0
species: 283419

283419
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_acyl_carrier_protein_C11H21N2O7PRS

385171
type: SpeciesReference
stoichiometry: 3.0
species: 284796

385232
type: SpeciesReference
stoichiometry: 1.0
species: 284001

297671
type: LocalParameter
value: 0.0

297670
type: LocalParameter
value: 0.0

297668
type: LocalParameter
value: 0.0

297667
type: LocalParameter
value: 999999.0

297666
type: LocalParameter
value: 0.0

385183
type: SpeciesReference
stoichiometry: 1.0
species: 285204

285204
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

385256
type: SpeciesReference
stoichiometry: 1.0
species: 284766

287491
type: Reaction
notes: GENE_ASSOCIATION: YLR303W PROTEIN_ASSOCIATION: Met17 SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 4.2.99.10
reversible: false
name: R_O_acetylhomoserine__thiol__lyase
reactant: 352382
product: 352418
product: 352394
fast: false
reactant: 352370
kinetic law: 352430
product: 352406

352382
type: SpeciesReference
stoichiometry: 1.0
species: 283941

283941
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Methanethiol_CH4S

352418
type: SpeciesReference
stoichiometry: 1.0
species: 285264

285264
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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species: 283497

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species: 283554

283554
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initial amount: NaN
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292214
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292212
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292210
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292208
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352406
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species: 284787

289512
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reactant: 399638
name: R_homocitrate_synthase
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reversible: false
fast: false
product: 399674
product: 399699
product: 399686
reactant: 399650

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299012
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299011
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299009
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299008
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399638
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399662
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399674
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399699
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399686
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283647
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287881
type: Reaction
product: 361430
reactant: 361382
product: 361406
reactant: 361394
reactant: 361358
fast: false
name: R_C_4_sterol_methyl_oxidase__4_methylzymosterol_
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kinetic law: 361442
notes: GENE_ASSOCIATION: YGR060W PROTEIN_ASSOCIATION: Erg25 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS:
product: 361418
reversible: false

361430
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species: 286543

286543
type: Species
constant: false
boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_zymosterol_intermediate_1_C28H44O3

361382
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species: 285436

361406
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species: 284757

361394
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361358
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species: 283338

283338
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_methylzymosterol_C28H46O

361370
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species: 284787

293401
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293399
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293397
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293393
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361418
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species: 285421

287239
type: Reaction
reactant: 347287
notes: GENE_ASSOCIATION: ( YBR115C and YGL154C ) PROTEIN_ASSOCIATION: Lys25 SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 1.2.1.31
reactant: 347250
fast: false
kinetic law: 347348
product: 347299
reactant: 347262
reactant: 347274
product: 347324
product: 347312
reversible: false
name: R_L_aminoadipate_semialdehyde_dehydrogenase__NADH_
product: 347336

347287
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347250
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species: 283428

291459
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291457
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291455
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291453
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291451
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347299
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species: 283425

283425
type: Species
constant: false
boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_2_Aminoadipate_6_semialdehyde_C6H11NO3

347262
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stoichiometry: 1.0
species: 283830

347274
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347324
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347312
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347336
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species: 285796

288788
type: Reaction
kinetic law: 378054
product: 378042
reactant: 378030
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Melibiose_exchange

296722
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296720
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296719
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296718
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296716
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378042
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species: 286873

286873
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Melibiose_C12H22O11

378030
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species: 285258

285258
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Melibiose_C12H22O11

290300
type: Reaction
product: 425184
product: 425196
reactant: 425148
kinetic law: 425208
reactant: 425160
product: 425172
notes: GENE_ASSOCIATION: YMR020W PROTEIN_ASSOCIATION: Fms1 SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 1.5.3.11
reactant: 425136
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fast: false
reversible: false

425184
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species: 284747

284747
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Hydrogen_peroxide_H2O2

425196
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stoichiometry: 1.0
species: 286075

425148
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species: 285487

302102
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302100
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302099
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302097
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302096
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425160
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species: 286081

286081
type: Species
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initial concentration: NaN
initial amount: NaN
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name: M_Spermine_C10H30N4

425172
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species: 283737

283737
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3_Aminopropanal_C3H8NO

425136
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species: 284757

287188
type: Reaction
kinetic law: 346259
product: 346247
reactant: 346235
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_4_Aminobenzoate_mitochondrial_transport_via_diffusion

291306
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291304
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291302
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291300
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291298
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346247
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species: 283272

346235
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species: 283266

283266
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Aminobenzoate_C7H6NO2

285661
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initial amount: NaN
in compartment: 282879

287011
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Trehalose_C12H22O11

286690
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Deoxycytidine_C9H13N3O4

290434
type: Reaction
reactant: 429389
kinetic law: 429449
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Pyridoxine_Metabolism PROTEIN_CLASS: 2.7.1.35
fast: false
product: 429425
product: 429413
reactant: 429401
reversible: false
name: R_pyridoxal_kinase
product: 429437

429389
type: SpeciesReference
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species: 283830

302571
type: LocalParameter
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302569
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302568
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302566
type: LocalParameter
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302565
type: LocalParameter
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429425
type: SpeciesReference
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species: 284787

429413
type: SpeciesReference
stoichiometry: 1.0
species: 283602

429401
type: SpeciesReference
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species: 285937

285937
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Pyridoxal_C8H9NO3

429437
type: SpeciesReference
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species: 285934

285934
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Pyridoxal_5__phosphate_C8H8NO6P

287872
type: Reaction
fast: false
notes: GENE_ASSOCIATION: YLR100W PROTEIN_ASSOCIATION: Erg27 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS:
name: R_C_3_sterol_keto_reductase__4_methylzymosterol_
reversible: false
product: 361163
reactant: 361139
reactant: 361115
product: 361151
kinetic law: 361175
reactant: 361127

361163
type: SpeciesReference
stoichiometry: 1.0
species: 285421

361139
type: SpeciesReference
stoichiometry: 1.0
species: 285436

361115
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species: 283344

283344
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Methylzymosterol_intermediate_2_C28H44O

361151
type: SpeciesReference
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species: 283338

293373
type: LocalParameter
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293371
type: LocalParameter
value: 6.33E-4

293369
type: LocalParameter
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293367
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293365
type: LocalParameter
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361127
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species: 284787

289049
type: Reaction
product: 382139
product: 382126
product: 382114
reactant: 382090
fast: false
notes: GENE_ASSOCIATION: YER015W PROTEIN_ASSOCIATION: Faa2-p SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 6.2.1.3
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reactant: 382102
kinetic law: 382151
reversible: true
reactant: 382078

382139
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species: 285805

285805
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Diphosphate_HO7P2

382126
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stoichiometry: 1.0
species: 284127

382114
type: SpeciesReference
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species: 283722

283722
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_AMP_C10H12N5O7P

382090
type: SpeciesReference
stoichiometry: 1.0
species: 284025

284025
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Coenzyme_A_C21H32N7O16P3S

382102
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species: 284121

284121
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Decanoate__n_C100__C10H19O2

297441
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297439
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297438
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297437
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297435
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382078
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species: 283845

283089
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initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_phenylethanol_C8H10O

289063
type: Reaction
reactant: 382705
reversible: true
reactant: 382681
product: 382729
fast: false
notes: GENE_ASSOCIATION: YER015W PROTEIN_ASSOCIATION: Faa2-p SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 6.2.1.3
product: 382717
kinetic law: 382753
product: 382741
reactant: 382693
name: R_fatty_acid__CoA_ligase__hexadecanoate___peroxisomal

382705
type: SpeciesReference
stoichiometry: 1.0
species: 284834

284834
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Hexadecanoate__n_C160__C16H31O2

382681
type: SpeciesReference
stoichiometry: 1.0
species: 283845

382729
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species: 285778

285778
type: Species
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boundary condition: false
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382717
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species: 283722

297503
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297501
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297500
type: LocalParameter
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297499
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297497
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382741
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species: 285805

382693
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species: 284025

283674
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Allophanate_C2H3N2O3

285781
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M__R__Pantothenate_C9H16NO5

289253
type: Reaction
product: 391461
reactant: 391424
name: R_glycerol_3_phosphate_dehydrogenase__FAD___mitochondrial
kinetic law: 391473
notes: GENE_ASSOCIATION: YIL155C PROTEIN_ASSOCIATION: Gut2-m SUBSYSTEM: S_Glycerolipid_Metabolism PROTEIN_CLASS: 1.1.99.5
reversible: false
fast: false
product: 391449
reactant: 391437

391461
type: SpeciesReference
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species: 284412

284412
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

391424
type: SpeciesReference
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species: 284409

284409
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

298149
type: LocalParameter
value: 0.0

298147
type: LocalParameter
value: 3.700069

298146
type: LocalParameter
value: 0.0

298144
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298143
type: LocalParameter
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391449
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species: 284199

284199
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Dihydroxyacetone_phosphate_C3H5O6P

391437
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species: 284672

284672
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Glycerol_3_phosphate_C3H7O6P

287179
type: Reaction
kinetic law: 346151
product: 346139
reactant: 346126
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_4_aminobutanal_mitochondrial_transport_via_diffusion

291279
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291277
type: LocalParameter
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291275
type: LocalParameter
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291273
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291271
type: LocalParameter
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346139
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species: 283263

283263
type: Species
constant: false
boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_4_Aminobutanal_C4H10NO

346126
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species: 283260

283260
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Aminobutanal_C4H10NO

290204
type: Reaction
kinetic law: 421790
product: 421778
reactant: 421766
notes: GENE_ASSOCIATION: YBR196C PROTEIN_ASSOCIATION: Pgi1 SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 5.3.1.9
fast: false
reversible: true
name: R_glucose_6_phosphate_isomerase

301730
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301729
type: LocalParameter
value: 8.706604

301726
type: LocalParameter
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301725
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301722
type: LocalParameter
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421778
type: SpeciesReference
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species: 284403

421766
type: SpeciesReference
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species: 284523

283359
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_amino_1__5_phospho_D_ribosyl_imidazole_4_carboxylate_C9H11N3O9P

286450
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_UDPgalactose_C15H22N2O17P2

290552
type: Reaction
fast: false
product: 433310
reversible: false
notes: GENE_ASSOCIATION: YDR127W PROTEIN_ASSOCIATION: Aro1 SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 1.1.1.25
product: 433322
kinetic law: 433335
reactant: 433298
reactant: 433286
reactant: 433274
name: R_shikimate_dehydrogenase

433310
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species: 285421

433322
type: SpeciesReference
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species: 286048

286048
type: Species
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initial concentration: NaN
initial amount: NaN
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name: M_Shikimate_C7H9O5

302984
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302982
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value: 0.076083

302981
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302979
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302978
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433298
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species: 285436

433286
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433274
type: SpeciesReference
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species: 283149

283149
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3_Dehydroshikimate_C7H7O5

289197
type: Reaction
reversible: false
reactant: 389635
fast: false
reactant: 389611
name: R_FMN_adenylyltransferase
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Riboflavin_Metabolism PROTEIN_CLASS: 2.7.7.2
kinetic law: 389671
product: 389659
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reactant: 389623

389635
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389611
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species: 283836

297967
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297965
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297964
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297962
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297961
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389659
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species: 285799

389647
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389623
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species: 284457

284457
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_FMN_C17H19N4O9P

285152
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boundary condition: false
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initial amount: NaN
in compartment: 282871
name: M_L_Leucyl_tRNA_Leu__C6H12NOR

284256
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Dolichol_C15H28O

287800
type: Reaction
product: 359348
kinetic law: 359373
fast: false
reactant: 359312
notes: GENE_ASSOCIATION: YDR530C PROTEIN_ASSOCIATION: Apa2 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.7.7.53
reactant: 359324
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reversible: false
product: 359360
reactant: 359336

359348
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stoichiometry: 1.0
species: 283728

283728
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constant: false
boundary condition: false
has only substance units: false
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initial amount: NaN
in compartment: 282871

293155
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293153
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value: 0.0

293151
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value: 0.0

293149
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293147
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359312
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species: 283602

359324
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stoichiometry: 1.0
species: 283830

359360
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species: 285751

359336
type: SpeciesReference
stoichiometry: 1.0
species: 284787

287433
type: Reaction
notes: GENE_ASSOCIATION: YDR226W PROTEIN_ASSOCIATION: Adk1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS:
product: 351077
product: 351065
reactant: 351053
name: R_adentylate_kinase__GTP_
fast: false
kinetic law: 351089
reactant: 351041
reversible: true

351077
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species: 284562

351065
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species: 283602

351053
type: SpeciesReference
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species: 284732

292035
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292033
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value: -0.266906

292031
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292029
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value: 999999.0

292027
type: LocalParameter
value: -999999.0

351041
type: SpeciesReference
stoichiometry: 1.0
species: 283713

288704
type: Reaction
kinetic law: 377037
product: 377024
reactant: 377011
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Reduced_glutathione_exchange

296498
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296496
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296495
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296494
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296492
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377024
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species: 286789

286789
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constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Reduced_glutathione_C10H16N3O6S

377011
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species: 284723

284723
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Reduced_glutathione_C10H16N3O6S

289387
type: Reaction
product: 395891
product: 395867
kinetic law: 395903
reactant: 395843
product: 395879
fast: false
name: R_glutamyl_tRNA_synthetase__mitochondrial
notes: GENE_ASSOCIATION: YOL033W PROTEIN_ASSOCIATION: Mse1-m SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.17
reversible: false
reactant: 395831
reactant: 395855

395891
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stoichiometry: 1.0
species: 285799

395867
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stoichiometry: 1.0
species: 283716

298591
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298590
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298588
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value: 0.0

298587
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value: 999999.0

298586
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395843
type: SpeciesReference
stoichiometry: 1.0
species: 284624

395879
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stoichiometry: 1.0
species: 284645

284645
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Glutamyl_tRNA_Glu__C5H7NO3R

395831
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species: 283836

395855
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stoichiometry: 1.0
species: 286300

286300
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_tRNA__Glu__R

290338
type: Reaction
kinetic law: 426449
fast: false
reactant: 426364
reactant: 426376
product: 426412
notes: GENE_ASSOCIATION: YAR015W PROTEIN_ASSOCIATION: Ade1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.2.6
reactant: 426388
reversible: true
product: 426425
product: 426437
name: R_phosphoribosylaminoimidazolesuccinocarboxamide_synthase
product: 426400

302235
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value: 0.0

302233
type: LocalParameter
value: 0.028496

302232
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value: 0.0

302230
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value: 999999.0

302229
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value: -999999.0

426364
type: SpeciesReference
stoichiometry: 1.0
species: 283359

426376
type: SpeciesReference
stoichiometry: 1.0
species: 283800

426412
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stoichiometry: 1.0
species: 283602

426388
type: SpeciesReference
stoichiometry: 1.0
species: 283830

426425
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stoichiometry: 1.0
species: 284787

426437
type: SpeciesReference
stoichiometry: 1.0
species: 285751

426400
type: SpeciesReference
stoichiometry: 1.0
species: 282953

282953
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M__S__2_5_Amino_1__5_phospho_D_ribosyl_imidazole_4_carboxamidosuccinate_C13H15N4O12P

290686
type: Reaction
reversible: false
product: 437887
product: 437862
reactant: 437838
notes: GENE_ASSOCIATION: YOR143C PROTEIN_ASSOCIATION: Thi80 SUBSYSTEM: S_Thiamine_Metabolism PROTEIN_CLASS: 2.7.6.2
fast: false
name: R_thiamine_diphosphokinase
product: 437875
reactant: 437850
kinetic law: 437899

437887
type: SpeciesReference
stoichiometry: 1.0
species: 286192

286192
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Thiamine_diphosphate_C12H16N4O7P2S

437862
type: SpeciesReference
stoichiometry: 1.0
species: 283713

437838
type: SpeciesReference
stoichiometry: 1.0
species: 283830

437875
type: SpeciesReference
stoichiometry: 1.0
species: 284787

437850
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stoichiometry: 1.0
species: 286180

286180
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Thiamin_C12H17N4OS

303463
type: LocalParameter
value: -0.011879

303462
type: LocalParameter
value: 0.0

303460
type: LocalParameter
value: 0.0

303459
type: LocalParameter
value: 999999.0

303457
type: LocalParameter
value: 0.0

287382
type: Reaction
kinetic law: 350074
product: 350062
reactant: 350050
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: false
name: R_acetylcarnitine_transport_out_of_peroxisome

291880
type: LocalParameter
value: 0.0

291878
type: LocalParameter
value: 0.0

291876
type: LocalParameter
value: 0.0

291874
type: LocalParameter
value: 999999.0

291872
type: LocalParameter
value: 0.0

350062
type: SpeciesReference
stoichiometry: 1.0
species: 283566

283566
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_O_Acetylcarnitine_C9H17NO4

350050
type: SpeciesReference
stoichiometry: 1.0
species: 283572

283572
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_O_Acetylcarnitine_C9H17NO4

284532
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Galactose_C6H12O6

286840
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Inosine_C10H12N4O5

288671
type: Reaction
kinetic law: 376626
product: 376614
reactant: 376602
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_Galacturonate_exchange

296410
type: LocalParameter
value: 0.0

296408
type: LocalParameter
value: 0.0

296407
type: LocalParameter
value: 0.0

296406
type: LocalParameter
value: 999999.0

296404
type: LocalParameter
value: 0.0

376614
type: SpeciesReference
stoichiometry: 1.0
species: 286756

286756
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Galacturonate_C6H9O7

376602
type: SpeciesReference
stoichiometry: 1.0
species: 284538

284538
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Galacturonate_C6H9O7

288494
type: Reaction
kinetic law: 374487
product: 374475
reactant: 374463
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_phenylethanol_exchange

295913
type: LocalParameter
value: 0.0

295910
type: LocalParameter
value: 0.0

295907
type: LocalParameter
value: 0.0

295904
type: LocalParameter
value: 999999.0

295901
type: LocalParameter
value: 0.0

374475
type: SpeciesReference
stoichiometry: 1.0
species: 286579

286579
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_2_phenylethanol_C8H10O

374463
type: SpeciesReference
stoichiometry: 1.0
species: 283092

283092
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_2_phenylethanol_C8H10O

284061
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Cysteine_C3H7NO2S

289552
type: Reaction
reactant: 400904
fast: false
kinetic law: 400964
reactant: 400916
notes: GENE_ASSOCIATION: YCL030C PROTEIN_ASSOCIATION: His4 SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 1.1.1.23
reactant: 400892
product: 400940
name: R_histidinol_dehydrogenase
reversible: false
product: 400952
product: 400928

400904
type: SpeciesReference
stoichiometry: 1.0
species: 284912

299151
type: LocalParameter
value: 0.0

299150
type: LocalParameter
value: 0.019085

299148
type: LocalParameter
value: 0.0

299147
type: LocalParameter
value: 999999.0

299146
type: LocalParameter
value: 0.0

400916
type: SpeciesReference
stoichiometry: 2.0
species: 285396

400892
type: SpeciesReference
stoichiometry: 1.0
species: 284757

400940
type: SpeciesReference
stoichiometry: 1.0
species: 284897

284897
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Histidine_C6H9N3O2

400952
type: SpeciesReference
stoichiometry: 2.0
species: 285409

400928
type: SpeciesReference
stoichiometry: 3.0
species: 284787

287097
type: Reaction
kinetic law: 344835
product: 344823
reactant: 344811
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_methylpropanal_transport__extracellular_

291025
type: LocalParameter
value: 0.0

291023
type: LocalParameter
value: 0.0

291022
type: LocalParameter
value: 0.0

291021
type: LocalParameter
value: 999999.0

291019
type: LocalParameter
value: -999999.0

344823
type: SpeciesReference
stoichiometry: 1.0
species: 283068

283068
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_2_methylpropanal_C4H8O

344811
type: SpeciesReference
stoichiometry: 1.0
species: 283065

283065
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_methylpropanal_C4H8O

289425
type: Reaction
name: R_glycine_mitochondrial_transport_via_proton_symport
reactant: 397005
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
product: 397041
fast: false
reactant: 397017
kinetic law: 397053
reversible: true
product: 397029

397005
type: SpeciesReference
stoichiometry: 1.0
species: 284657

397041
type: SpeciesReference
stoichiometry: 1.0
species: 284796

397017
type: SpeciesReference
stoichiometry: 1.0
species: 284787

298728
type: LocalParameter
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298727
type: LocalParameter
value: 0.0

298725
type: LocalParameter
value: 0.0

298724
type: LocalParameter
value: 999999.0

298723
type: LocalParameter
value: -999999.0

397029
type: SpeciesReference
stoichiometry: 1.0
species: 284663

290614
type: Reaction
product: 435284
reactant: 435272
fast: false
reversible: false
kinetic law: 435308
name: R_sucrose_hydrolyzing_enxyme__extracellular
reactant: 435260
product: 435296
notes: GENE_ASSOCIATION: YIL162W PROTEIN_ASSOCIATION: Suc2-e SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.26

435284
type: SpeciesReference
stoichiometry: 1.0
species: 284490

435272
type: SpeciesReference
stoichiometry: 1.0
species: 286123

303211
type: LocalParameter
value: 0.0

303209
type: LocalParameter
value: 0.0

303208
type: LocalParameter
value: 0.0

303206
type: LocalParameter
value: 999999.0

303205
type: LocalParameter
value: 0.0

435260
type: SpeciesReference
stoichiometry: 1.0
species: 284760

284760
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_H2O_H2O

435296
type: SpeciesReference
stoichiometry: 1.0
species: 284589

284589
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Glucose_C6H12O6

290088
type: Reaction
reactant: 418319
reversible: false
product: 418381
reactant: 418344
fast: false
kinetic law: 418394
name: R_2_Oxobutanoate_dehydrogenase
product: 418356
reactant: 418331
product: 418368
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 1.2.7.2

418319
type: SpeciesReference
stoichiometry: 1.0
species: 283077

283077
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_Oxobutanoate_C4H5O3

418381
type: SpeciesReference
stoichiometry: 1.0
species: 285790

418344
type: SpeciesReference
stoichiometry: 1.0
species: 285399

301206
type: LocalParameter
value: 0.0

301203
type: LocalParameter
value: 0.0

301202
type: LocalParameter
value: 0.0

301199
type: LocalParameter
value: 999999.0

301198
type: LocalParameter
value: 0.0

418356
type: SpeciesReference
stoichiometry: 1.0
species: 284001

418331
type: SpeciesReference
stoichiometry: 1.0
species: 284016

418368
type: SpeciesReference
stoichiometry: 1.0
species: 285412

285059
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Inosine_C10H12N4O5

288073
type: Reaction
kinetic law: 365419
product: 365407
reactant: 365395
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_L_carnitine_transport_out_of_mitochondria_via_diffusion

294080
type: LocalParameter
value: 0.0

294077
type: LocalParameter
value: 0.0

294074
type: LocalParameter
value: 0.0

294071
type: LocalParameter
value: 999999.0

294068
type: LocalParameter
value: 0.0

365407
type: SpeciesReference
stoichiometry: 1.0
species: 284034

284034
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Carnitine_C7H15NO3

365395
type: SpeciesReference
stoichiometry: 1.0
species: 284040

283623
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_ADPribose_C15H21N5O14P2

289391
type: Reaction
name: R_L_glutamate_transport_via_proton_symport__reversible
reactant: 395987
notes: GENE_ASSOCIATION: ( YFL055W or YDR536W or YKR039W or YCL025C or YPL265W ) PROTEIN_ASSOCIATION: ( Agp3 ) or ( Stl1 ) or ( Gap1 ) or ( Agp1 ) or ( Dip5 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
product: 396011
reactant: 395975
fast: false
product: 395999
kinetic law: 396023
reversible: true

395987
type: SpeciesReference
stoichiometry: 1.0
species: 284790

396011
type: SpeciesReference
stoichiometry: 1.0
species: 284787

395975
type: SpeciesReference
stoichiometry: 1.0
species: 284621

284621
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Glutamate_C5H8NO4

395999
type: SpeciesReference
stoichiometry: 1.0
species: 284618

298606
type: LocalParameter
value: 0.0

298605
type: LocalParameter
value: 0.0

298603
type: LocalParameter
value: 0.0

298602
type: LocalParameter
value: 999999.0

298600
type: LocalParameter
value: -999999.0

288310
type: Reaction
product: 370671
kinetic law: 370696
fast: false
name: R_Dolichyl_phosphate_mannose__protein_mannosyltransferase__endoplasmic_reticular
product: 370684
notes: GENE_ASSOCIATION: ( ( YDL095W and YAL023C ) or YOR321W or YJR143C or YDL093W or YGR199W ) PROTEIN_ASSOCIATION: ( Pmt1-er and Pmt2-er ) or ( Pmt3-er ) or ( Pmt4-er ) or ( Pmt5-er ) or ( Pmt6-er ) SUBSYSTEM: S_Glycoprotein_Metabolism PROTEIN_CLASS: 2.4.1.109
reactant: 370647
reversible: false
product: 370659

370671
type: SpeciesReference
stoichiometry: 1.0
species: 284802

295107
type: LocalParameter
value: 0.0

295104
type: LocalParameter
value: 0.232567

295101
type: LocalParameter
value: 0.0

295098
type: LocalParameter
value: 999999.0

295095
type: LocalParameter
value: 0.0

370684
type: SpeciesReference
stoichiometry: 1.0
species: 285252

285252
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Mannan_C6H10O5

370647
type: SpeciesReference
stoichiometry: 1.0
species: 284259

370659
type: SpeciesReference
stoichiometry: 1.0
species: 284265

284265
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Dolichol_phosphate_C15H27O4P

286366
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_tRNA_Val__R

290342
type: Reaction
kinetic law: 426643
product: 426631
name: R_phosphoribosylformylglycinamidine_synthase
product: 426594
reactant: 426534
reactant: 426546
product: 426582
fast: false
reactant: 426558
reversible: false
product: 426618
reactant: 426570
product: 426606
notes: GENE_ASSOCIATION: YGR061C PROTEIN_ASSOCIATION: Ade6 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.5.3

302249
type: LocalParameter
value: 0.0

302247
type: LocalParameter
value: 0.028496

302246
type: LocalParameter
value: 0.0

302244
type: LocalParameter
value: 999999.0

302243
type: LocalParameter
value: 0.0

426631
type: SpeciesReference
stoichiometry: 1.0
species: 285751

426594
type: SpeciesReference
stoichiometry: 1.0
species: 284475

284475
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2__Formamido__N1__5_phospho_D_ribosyl_acetamidine_C8H15N3O8P

426534
type: SpeciesReference
stoichiometry: 1.0
species: 283830

426546
type: SpeciesReference
stoichiometry: 1.0
species: 284442

284442
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N2_Formyl_N1__5_phospho_D_ribosyl_glycinamide_C8H13N2O9P

426582
type: SpeciesReference
stoichiometry: 1.0
species: 283602

426558
type: SpeciesReference
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species: 284595

426618
type: SpeciesReference
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species: 284787

426570
type: SpeciesReference
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species: 284757

426606
type: SpeciesReference
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species: 284618

289089
type: Reaction
reactant: 383915
reactant: 383879
product: 383963
name: R_Fatty_acid_oxidation
reactant: 383855
product: 383975
product: 383939
kinetic law: 383987
product: 383951
product: 383927
reactant: 383867
notes: GENE_ASSOCIATION: ( ( YLR284C and YKR009C and YIL160C and YGL205W and YNL202W ) or ( YOR180C and YKR009C and YIL160C and YGL205W and YNL202W ) or ( YOR180C and YLR284C and YKR009C and YIL160C and YGL205W and YNL202W ) ) PROTEIN_ASSOCIATION: ( Eci1-p and Fox2-p and Pot1-p and Pox1-p and Sps19-p ) or ( Dci1-p and Fox2-p and Pot1-p and Pox1-p and Sps19-p ) or ( Dci1-p and Eci1-p and Fox2-p and Pot1-p and Pox1-p and Sps19-p ) SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS:
reversible: false
reactant: 383891
fast: false
reactant: 383903

383915
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stoichiometry: 7.0
species: 285499

383879
type: SpeciesReference
stoichiometry: 1.0
species: 284849

284849
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

383963
type: SpeciesReference
stoichiometry: 7.0
species: 285418

285418
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

383855
type: SpeciesReference
stoichiometry: 7.0
species: 284025

383975
type: SpeciesReference
stoichiometry: 1.0
species: 285433

285433
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

383939
type: SpeciesReference
stoichiometry: 6.0
species: 284808

297603
type: LocalParameter
value: 0.0

297600
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value: 0.0

297599
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value: 0.0

297598
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value: 999999.0

297596
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value: 0.0

383951
type: SpeciesReference
stoichiometry: 7.0
species: 284754

383927
type: SpeciesReference
stoichiometry: 8.0
species: 283530

383867
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stoichiometry: 7.0
species: 284778

383891
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stoichiometry: 7.0
species: 285406

285406
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

383903
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stoichiometry: 1.0
species: 285445

285445
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

290690
type: Reaction
reactant: 437971
reactant: 437984
name: R_thiamine_diphosphate_kinase
notes: GENE_ASSOCIATION: YOR143C PROTEIN_ASSOCIATION: Thi80 SUBSYSTEM: S_Thiamine_Metabolism PROTEIN_CLASS: 2.7.4.15
reversible: false
kinetic law: 438020
product: 437996
product: 438008
fast: false

437971
type: SpeciesReference
stoichiometry: 1.0
species: 283830

437984
type: SpeciesReference
stoichiometry: 1.0
species: 286192

303477
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value: -0.146903

303476
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value: 0.0

303474
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value: 0.0

303473
type: LocalParameter
value: 999999.0

303471
type: LocalParameter
value: 0.0

437996
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stoichiometry: 1.0
species: 283602

438008
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stoichiometry: 1.0
species: 286201

286201
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Thiamin_triphosphate_C12H16N4O10P3S

286948
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Putrescine_C4H14N2

287269
type: Reaction
product: 347906
name: R_acetyl_CoA_C_acetyltransferase__dodecanoyl___peroxisomal
fast: false
reactant: 347894
kinetic law: 347930
reactant: 347882
reversible: false
product: 347918
notes: GENE_ASSOCIATION: YIL160C PROTEIN_ASSOCIATION: Pot1-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 2.3.1.16

347906
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stoichiometry: 1.0
species: 283530

347894
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stoichiometry: 1.0
species: 284025

291548
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291546
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291544
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value: 0.0

291542
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291540
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value: 0.0

347882
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stoichiometry: 1.0
species: 283230

283230
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_3_Oxotetradecanoyl_CoA_C35H56N7O18P3S

347918
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stoichiometry: 1.0
species: 284172

284172
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

290460
type: Reaction
product: 430285
reversible: false
name: R_Quinolinate_Synthase__Eukaryotic_
fast: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Quinone_Biosynthesis PROTEIN_CLASS:
product: 430260
reactant: 430248
kinetic law: 430298
product: 430273

430285
type: SpeciesReference
stoichiometry: 1.0
species: 285961

285961
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Quinolinate_C7H3NO4

430260
type: SpeciesReference
stoichiometry: 1.0
species: 284787

430248
type: SpeciesReference
stoichiometry: 1.0
species: 283989

283989
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Amino_3_carboxymuconate_semialdehyde_C7H6NO5

302662
type: LocalParameter
value: 0.0

302660
type: LocalParameter
value: 0.0

302659
type: LocalParameter
value: 0.0

302657
type: LocalParameter
value: 999999.0

302656
type: LocalParameter
value: 0.0

430273
type: SpeciesReference
stoichiometry: 1.0
species: 284757

289988
type: Reaction
notes: GENE_ASSOCIATION: YER005W PROTEIN_ASSOCIATION: Ynd1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.6.1.6
product: 415393
product: 415406
reactant: 415357
reactant: 415369
fast: false
name: R_nucleoside_diphosphatase__UDP_
product: 415381
kinetic law: 415418
reversible: false

415393
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stoichiometry: 1.0
species: 285751

415406
type: SpeciesReference
stoichiometry: 1.0
species: 286456

286456
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_UMP_C9H11N2O9P

415357
type: SpeciesReference
stoichiometry: 1.0
species: 284757

415369
type: SpeciesReference
stoichiometry: 1.0
species: 286438

286438
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_UDP_C9H11N2O12P2

415381
type: SpeciesReference
stoichiometry: 1.0
species: 284787

300774
type: LocalParameter
value: -0.011879

300771
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value: 0.0

300770
type: LocalParameter
value: 0.0

300767
type: LocalParameter
value: 999999.0

300766
type: LocalParameter
value: 0.0

285475
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_NMN_C11H14N2O8P

287473
type: Reaction
reactant: 351913
reactant: 351937
reactant: 351925
notes: GENE_ASSOCIATION: YDL052C PROTEIN_ASSOCIATION: Slc1 SUBSYSTEM: S_Phospholipid_Biosynthesis PROTEIN_CLASS: 2.3.1.51
reactant: 351961
fast: false
reactant: 351997
reactant: 352009
kinetic law: 352045
name: R_1_Acyl_glycerol_3_phosphate_acyltransferase__yeast_specific
reactant: 351949
product: 352021
product: 352033
reactant: 351973
reactant: 351985
reversible: false

351913
type: SpeciesReference
stoichiometry: 0.01
species: 282917

282917
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

351937
type: SpeciesReference
stoichiometry: 0.06
species: 284169

351925
type: SpeciesReference
stoichiometry: 0.02
species: 284124

351961
type: SpeciesReference
stoichiometry: 0.09
species: 285556

351997
type: SpeciesReference
stoichiometry: 0.05
species: 286099

352009
type: SpeciesReference
stoichiometry: 0.1
species: 286150

292162
type: LocalParameter
value: 0.0

292160
type: LocalParameter
value: 0.00711

292158
type: LocalParameter
value: 0.0

292156
type: LocalParameter
value: 999999.0

292154
type: LocalParameter
value: 0.0

351949
type: SpeciesReference
stoichiometry: 0.17
species: 284846

352021
type: SpeciesReference
stoichiometry: 1.0
species: 284013

352033
type: SpeciesReference
stoichiometry: 0.01
species: 285613

285613
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

351973
type: SpeciesReference
stoichiometry: 0.24
species: 285577

351985
type: SpeciesReference
stoichiometry: 0.27
species: 285775

289606
type: Reaction
kinetic law: 402775
product: 402763
reactant: 402751
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: false
name: R_Isoamyl_acetate_transport__extracellular_

299339
type: LocalParameter
value: -0.023956

299337
type: LocalParameter
value: 0.0

299336
type: LocalParameter
value: 0.0

299334
type: LocalParameter
value: 999999.0

299333
type: LocalParameter
value: 0.0

402763
type: SpeciesReference
stoichiometry: 1.0
species: 284954

284954
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_isoamyl_acetate_C7H14O2

402751
type: SpeciesReference
stoichiometry: 1.0
species: 284951

284951
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_isoamyl_acetate_C7H14O2

290282
type: Reaction
product: 424544
name: R_5_diphosphoinositol_1_2_3_4_6_pentakisphosphate_synthase
product: 424532
reactant: 424508
kinetic law: 424556
notes: GENE_ASSOCIATION: YDR017C PROTEIN_ASSOCIATION: Kcs1 SUBSYSTEM: S_Phospholipid_Metabolism PROTEIN_CLASS:
fast: false
reversible: false
reactant: 424520

424544
type: SpeciesReference
stoichiometry: 1.0
species: 285808

285808
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_Diphosphoinositol_pentakisphosphate_C6H6O27P7

424532
type: SpeciesReference
stoichiometry: 1.0
species: 283602

424508
type: SpeciesReference
stoichiometry: 1.0
species: 283830

302040
type: LocalParameter
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302039
type: LocalParameter
value: 0.0

302037
type: LocalParameter
value: 0.0

302036
type: LocalParameter
value: 999999.0

302034
type: LocalParameter
value: 0.0

424520
type: SpeciesReference
stoichiometry: 1.0
species: 285315

285315
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_myo_Inositol_hexakisphosphate_C6H6O24P6

290594
type: Reaction
kinetic law: 434681
product: 434668
reactant: 434656
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Endoplasmic_Reticular PROTEIN_CLASS:
fast: false
reversible: true
name: R_squalene_endoplamic_reticular_transport

303130
type: LocalParameter
value: 0.0

303129
type: LocalParameter
value: 6.33E-4

303127
type: LocalParameter
value: 0.0

303126
type: LocalParameter
value: 999999.0

303125
type: LocalParameter
value: -999999.0

434668
type: SpeciesReference
stoichiometry: 1.0
species: 286090

434656
type: SpeciesReference
stoichiometry: 1.0
species: 286087

286087
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Squalene_C30H50

289093
type: Reaction
reactant: 384132
reactant: 384180
product: 384216
reactant: 384144
reactant: 384120
product: 384228
notes: GENE_ASSOCIATION: ( ( YLR284C and YKR009C and YIL160C and YGL205W and YNL202W ) or ( YOR180C and YKR009C and YIL160C and YGL205W and YNL202W ) or ( YOR180C and YLR284C and YKR009C and YIL160C and YGL205W and YNL202W ) ) PROTEIN_ASSOCIATION: ( Eci1-p and Fox2-p and Pot1-p and Pox1-p and Sps19-p ) or ( Dci1-p and Fox2-p and Pot1-p and Pox1-p and Sps19-p ) or ( Dci1-p and Eci1-p and Fox2-p and Pot1-p and Pox1-p and Sps19-p ) SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS:
product: 384204
product: 384240
reactant: 384156
kinetic law: 384252
product: 384192
reversible: false
fast: false
name: R_Fatty_acid_oxidation
reactant: 384168

384132
type: SpeciesReference
stoichiometry: 8.0
species: 284778

384180
type: SpeciesReference
stoichiometry: 1.0
species: 285580

285580
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

384216
type: SpeciesReference
stoichiometry: 8.0
species: 284754

384144
type: SpeciesReference
stoichiometry: 8.0
species: 285406

384120
type: SpeciesReference
stoichiometry: 8.0
species: 284025

384228
type: SpeciesReference
stoichiometry: 8.0
species: 285418

384204
type: SpeciesReference
stoichiometry: 7.0
species: 284808

384240
type: SpeciesReference
stoichiometry: 1.0
species: 285433

384156
type: SpeciesReference
stoichiometry: 1.0
species: 285445

297618
type: LocalParameter
value: -0.067116

297617
type: LocalParameter
value: 0.0

297615
type: LocalParameter
value: 0.0

297614
type: LocalParameter
value: 999999.0

297612
type: LocalParameter
value: 0.0

384192
type: SpeciesReference
stoichiometry: 9.0
species: 283530

384168
type: SpeciesReference
stoichiometry: 8.0
species: 285499

283680
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Allantoin_C4H6N4O3

287464
type: Reaction
kinetic law: 351757
product: 351745
product: 351733
reactant: 351721
notes: GENE_ASSOCIATION: YLR359W PROTEIN_ASSOCIATION: Ade13 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 4.3.2.2
fast: false
reversible: true
name: R_adenylsuccinate_lyase

292135
type: LocalParameter
value: 0.0

292133
type: LocalParameter
value: 0.033364

292131
type: LocalParameter
value: 0.0

292128
type: LocalParameter
value: 999999.0

292126
type: LocalParameter
value: -999999.0

351745
type: SpeciesReference
stoichiometry: 1.0
species: 284493

351733
type: SpeciesReference
stoichiometry: 1.0
species: 283713

351721
type: SpeciesReference
stoichiometry: 1.0
species: 284130

284130
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N6__1_2_Dicarboxyethyl__AMP_C14H14N5O11P

290234
type: Reaction
name: R_phosphatidylinositol_3_phosphate_4_kinase__yeast_specific
product: 422694
reactant: 422658
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Phospholipid_Biosynthesis PROTEIN_CLASS:
reversible: false
product: 422706
fast: false
product: 422682
reactant: 422670
kinetic law: 422718

422694
type: SpeciesReference
stoichiometry: 1.0
species: 284787

422658
type: SpeciesReference
stoichiometry: 1.0
species: 283830

422706
type: SpeciesReference
stoichiometry: 0.01
species: 285889

285889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

422682
type: SpeciesReference
stoichiometry: 1.0
species: 283602

422670
type: SpeciesReference
stoichiometry: 0.01
species: 285910

285910
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

301865
type: LocalParameter
value: -0.756738

301864
type: LocalParameter
value: 0.0

301861
type: LocalParameter
value: 0.0

301860
type: LocalParameter
value: 999999.0

301857
type: LocalParameter
value: 0.0

286183
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Thiamin_C12H17N4OS

287830
type: Reaction
reactant: 360064
product: 360101
name: R_ADPATP_transporter__mitochondrial
kinetic law: 360137
product: 360125
reactant: 360089
reactant: 360077
product: 360113
reversible: false
notes: GENE_ASSOCIATION: ( YBR085W or YBL030C or YMR056C ) PROTEIN_ASSOCIATION: ( Aac3-m ) or ( Pet9-m ) or ( Aac1-m ) SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false

360064
type: SpeciesReference
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species: 283602

360101
type: SpeciesReference
stoichiometry: 1.0
species: 283830

293245
type: LocalParameter
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293243
type: LocalParameter
value: 4.455985

293241
type: LocalParameter
value: 0.0

293239
type: LocalParameter
value: 999999.0

293237
type: LocalParameter
value: 0.0

360125
type: SpeciesReference
stoichiometry: 1.0
species: 284796

360089
type: SpeciesReference
stoichiometry: 1.0
species: 283836

360077
type: SpeciesReference
stoichiometry: 1.0
species: 284787

360113
type: SpeciesReference
stoichiometry: 1.0
species: 283608

283608
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_ADP_C10H12N5O10P2

288734
type: Reaction
kinetic law: 377397
product: 377385
reactant: 377373
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Isoamyl_alcohol_exchange

296578
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value: 0.0

296576
type: LocalParameter
value: 0.0

296575
type: LocalParameter
value: 0.0

296574
type: LocalParameter
value: 999999.0

296572
type: LocalParameter
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377385
type: SpeciesReference
stoichiometry: 1.0
species: 286819

377373
type: SpeciesReference
stoichiometry: 1.0
species: 284962

284962
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Isoamyl_alcohol_C5H12O

287152
type: Reaction
kinetic law: 345763
product: 345751
reactant: 345739
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_3_methylbutanal_transport__extracellular_

291193
type: LocalParameter
value: 0.0

291191
type: LocalParameter
value: 0.0

291189
type: LocalParameter
value: 0.0

291187
type: LocalParameter
value: 999999.0

291185
type: LocalParameter
value: -999999.0

345751
type: SpeciesReference
stoichiometry: 1.0
species: 283188

283188
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_3_Methylbutanal_C5H10O

345739
type: SpeciesReference
stoichiometry: 1.0
species: 283185

283185
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3_Methylbutanal_C5H10O

289904
type: Reaction
reactant: 412526
fast: false
notes: GENE_ASSOCIATION: YER019W PROTEIN_ASSOCIATION: Isc1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
product: 412562
reversible: false
kinetic law: 412574
product: 412550
product: 412538
name: R_Mannose_inositol_phosphorylceramide__ceramide_2__24C__phospholipase_C
reactant: 412514

412526
type: SpeciesReference
stoichiometry: 0.01
species: 285345

285345
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

412562
type: SpeciesReference
stoichiometry: 1.0
species: 285246

285246
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_mannose_1D_myo_Inositol_1_phosphate_C12H21O14P1

300427
type: LocalParameter
value: -0.033063

300426
type: LocalParameter
value: 0.0

300424
type: LocalParameter
value: 0.0

300423
type: LocalParameter
value: 999999.0

300420
type: LocalParameter
value: 0.0

412550
type: SpeciesReference
stoichiometry: 1.0
species: 284787

412538
type: SpeciesReference
stoichiometry: 1.0
species: 283914

412514
type: SpeciesReference
stoichiometry: 1.0
species: 284757

289610
type: Reaction
kinetic law: 402848
product: 402836
reactant: 402824
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_isoamyl_alcohol_transport__mitochondrial_

299353
type: LocalParameter
value: 0.0

299351
type: LocalParameter
value: 0.0

299350
type: LocalParameter
value: 0.0

299348
type: LocalParameter
value: 999999.0

299347
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value: -999999.0

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species: 284963

284963
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Isoamyl_alcohol_C5H12O

402824
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species: 284961

284961
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Isoamyl_alcohol_C5H12O

288869
type: Reaction
kinetic law: 379036
product: 379024
reactant: 379012
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_Ribose_exchange

296938
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value: -0.019798

296936
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value: 0.0

296935
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value: 0.0

296934
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value: 999999.0

296932
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value: 0.0

379024
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stoichiometry: 1.0
species: 286954

286954
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Ribose_C5H10O5

379012
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stoichiometry: 1.0
species: 285982

285982
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Ribose_C5H10O5

283431
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Cystine_C6H12N2O4S2

290368
type: Reaction
reactant: 427380
fast: false
product: 427416
notes: GENE_ASSOCIATION: YER026C PROTEIN_ASSOCIATION: Cho1-m SUBSYSTEM: S_Phospholipid_Biosynthesis PROTEIN_CLASS: 2.7.8.8
product: 427392
reactant: 427368
product: 427404
name: R_phosphatidylserine_synthase__yeast_specific__mitochondrial
kinetic law: 427428
reversible: true

427380
type: SpeciesReference
stoichiometry: 1.0
species: 286036

286036
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Serine_C3H7NO3

427416
type: SpeciesReference
stoichiometry: 0.01
species: 285865

285865
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

427392
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stoichiometry: 1.0
species: 283986

283986
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_CMP_C9H12N3O8P

427368
type: SpeciesReference
stoichiometry: 0.01
species: 283896

283896
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

427404
type: SpeciesReference
stoichiometry: 1.0
species: 284796

302340
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value: 0.0

302338
type: LocalParameter
value: 0.0

302337
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value: 0.0

302335
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value: 999999.0

302334
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value: -999999.0

289211
type: Reaction
fast: false
reversible: false
reactant: 389999
notes: GENE_ASSOCIATION: YEL047C PROTEIN_ASSOCIATION: Frds1 SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS: 1.3.99.1
kinetic law: 390047
product: 390035
reactant: 390011
product: 390023
name: R_fumarate_reductase__cytosolicmitochondrial

389999
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stoichiometry: 1.0
species: 284493

298012
type: LocalParameter
value: 0.0

298011
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value: 0.0

298009
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value: 0.0

298008
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value: 999999.0

298006
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value: 0.0

390035
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stoichiometry: 1.0
species: 284409

390011
type: SpeciesReference
stoichiometry: 1.0
species: 284412

390023
type: SpeciesReference
stoichiometry: 1.0
species: 286105

289694
type: Reaction
name: R_Inositol_phosphorylceramide_synthase__ceramide_3__26C___yeast_specific
notes: GENE_ASSOCIATION: YKL004W PROTEIN_ASSOCIATION: Aur1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
reversible: false
product: 405363
kinetic law: 405388
product: 405376
fast: false
reactant: 405339
reactant: 405351

405363
type: SpeciesReference
stoichiometry: 0.01
species: 282893

299650
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value: 0.0

299648
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value: 0.0

299647
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value: 0.0

299646
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value: 999999.0

299644
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value: 0.0

405376
type: SpeciesReference
stoichiometry: 0.01
species: 285080

285080
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

405339
type: SpeciesReference
stoichiometry: 1.0
species: 283935

283935
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_3__Phytosphingosinen_C260OH__C44H89NO5

405351
type: SpeciesReference
stoichiometry: 0.01
species: 285898

290510
type: Reaction
kinetic law: 431907
product: 431895
reactant: 431883
notes: GENE_ASSOCIATION: YOR095C PROTEIN_ASSOCIATION: Rki1 SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 5.3.1.6
fast: false
reversible: true
name: R_ribose_5_phosphate_isomerase

302837
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value: 0.0

302835
type: LocalParameter
value: -0.351057

302834
type: LocalParameter
value: 0.0

302832
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value: 999999.0

302831
type: LocalParameter
value: -999999.0

431895
type: SpeciesReference
stoichiometry: 1.0
species: 285997

285997
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Ribulose_5_phosphate_C5H9O8P

431883
type: SpeciesReference
stoichiometry: 1.0
species: 285973

285655
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

285002
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_IDP_C10H11N4O11P2

284214
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Dihydroneopterin_C9H13N5O4

283599
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Adenosine_C10H13N5O4

285634
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

289147
type: Reaction
name: R_fatty_acyl_ACP_synthase__n_C181ACP___mitochondrial
fast: false
reactant: 387575
product: 387623
notes: GENE_ASSOCIATION: ( YKL192C and YER061C and YHR067W and YOR221C and YBR026C and YKL055C ) PROTEIN_ASSOCIATION: ( Acp1-m and Cem1-m and Htd2-m and Mct1-m and Mrf1-m and Oar1-m ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS:
reactant: 387538
reactant: 387551
reversible: false
reactant: 387526
reactant: 387563
product: 387599
product: 387611
product: 387635
kinetic law: 387647
product: 387587

387575
type: SpeciesReference
stoichiometry: 1.0
species: 285637

285637
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

387623
type: SpeciesReference
stoichiometry: 3.0
species: 285427

387538
type: SpeciesReference
stoichiometry: 1.0
species: 285204

387551
type: SpeciesReference
stoichiometry: 3.0
species: 285439

387526
type: SpeciesReference
stoichiometry: 4.0
species: 284796

387563
type: SpeciesReference
stoichiometry: 1.0
species: 285493

285493
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_O2_O2

387599
type: SpeciesReference
stoichiometry: 1.0
species: 284001

387611
type: SpeciesReference
stoichiometry: 3.0
species: 284766

387635
type: SpeciesReference
stoichiometry: 1.0
species: 285571

285571
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

297797
type: LocalParameter
value: 0.0

297796
type: LocalParameter
value: 0.0

297794
type: LocalParameter
value: 0.0

297793
type: LocalParameter
value: 999999.0

297792
type: LocalParameter
value: 0.0

387587
type: SpeciesReference
stoichiometry: 1.0
species: 283419

283437
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Formylkynurenine_C11H12N2O4

288262
type: Reaction
fast: false
product: 369677
reactant: 369653
kinetic law: 369702
reversible: false
name: R_dihydoorotic_acid__ubiquinone_6___irreversible
notes: GENE_ASSOCIATION: YKL216W PROTEIN_ASSOCIATION: Ura1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 1.3.3.1
product: 369689
reactant: 369665

369677
type: SpeciesReference
stoichiometry: 1.0
species: 285604

285604
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Orotate_C5H3N2O4

369653
type: SpeciesReference
stoichiometry: 1.0
species: 284220

284220
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M__S__Dihydroorotate_C5H5N2O4

294899
type: LocalParameter
value: 0.0

294896
type: LocalParameter
value: 0.031838

294893
type: LocalParameter
value: 0.0

294890
type: LocalParameter
value: 999999.0

294887
type: LocalParameter
value: 0.0

369689
type: SpeciesReference
stoichiometry: 1.0
species: 285958

285958
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Ubiquinol_6_C39H60O4

369665
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stoichiometry: 1.0
species: 285955

285955
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Ubiquinone_6_C39H58O4

289766
type: Reaction
kinetic law: 408133
product: 408121
name: R_Lysyl_tRNA_synthetase__mitochondrial
reactant: 408085
fast: false
reactant: 408060
reversible: false
reactant: 408072
product: 408097
notes: GENE_ASSOCIATION: YNL073W PROTEIN_ASSOCIATION: Msk1-m SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.6
product: 408109

299905
type: LocalParameter
value: -0.073451

299903
type: LocalParameter
value: 0.0

299902
type: LocalParameter
value: 0.0

299900
type: LocalParameter
value: 999999.0

299899
type: LocalParameter
value: 0.0

408121
type: SpeciesReference
stoichiometry: 1.0
species: 285799

408085
type: SpeciesReference
stoichiometry: 1.0
species: 286327

286327
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_tRNA_Lys__R

408060
type: SpeciesReference
stoichiometry: 1.0
species: 283836

408072
type: SpeciesReference
stoichiometry: 1.0
species: 285174

285174
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Lysine_C6H15N2O2

408097
type: SpeciesReference
stoichiometry: 1.0
species: 283716

408109
type: SpeciesReference
stoichiometry: 1.0
species: 285183

285183
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Lysine_tRNA__Lys__C6H14N2OR

285231
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Mannose_1_phosphate_C6H11O9P

286216
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Threonyl_tRNA_Thr__C4H8NO2R

288031
type: Reaction
kinetic law: 364729
product: 364717
reactant: 364705
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_CO2_transporter_via_diffusion

293913
type: LocalParameter
value: 0.0

293910
type: LocalParameter
value: -18.021084

293907
type: LocalParameter
value: 0.0

293906
type: LocalParameter
value: 999999.0

293905
type: LocalParameter
value: -999999.0

364717
type: SpeciesReference
stoichiometry: 1.0
species: 283992

364705
type: SpeciesReference
stoichiometry: 1.0
species: 283995

288620
type: Reaction
kinetic law: 376008
product: 375996
reactant: 375984
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Deoxyuridine_exchange

296274
type: LocalParameter
value: -0.099387

296272
type: LocalParameter
value: 0.0

296271
type: LocalParameter
value: 0.0

296270
type: LocalParameter
value: 999999.0

296268
type: LocalParameter
value: 0.0

375996
type: SpeciesReference
stoichiometry: 1.0
species: 286705

286705
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Deoxyuridine_C9H12N2O5

375984
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stoichiometry: 1.0
species: 284310

284310
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Deoxyuridine_C9H12N2O5

283026
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_hexaprenyl_3_methyl_6_methoxy_1_4_benzoquinone_C38H56O3

288166
type: Reaction
reversible: false
product: 367563
fast: false
reactant: 367514
kinetic law: 367575
name: R_diacylglycerol_cholinephosphotransferase__yeast_specific
reactant: 367526
product: 367538
notes: GENE_ASSOCIATION: ( YNL130C or YHR123W ) PROTEIN_ASSOCIATION: ( Cpt1 ) or ( Ept1 ) SUBSYSTEM: S_Phospholipid_Biosynthesis PROTEIN_CLASS: 2.7.8.2
product: 367551

367563
type: SpeciesReference
stoichiometry: 0.01
species: 285670

285670
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

367514
type: SpeciesReference
stoichiometry: 0.01
species: 282893

294483
type: LocalParameter
value: 0.0

294480
type: LocalParameter
value: 0.0

294477
type: LocalParameter
value: 0.0

294474
type: LocalParameter
value: 999999.0

294471
type: LocalParameter
value: 0.0

367526
type: SpeciesReference
stoichiometry: 1.0
species: 283890

283890
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_CDPcholine_C14H25N4O11P2

367538
type: SpeciesReference
stoichiometry: 1.0
species: 283983

283983
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_CMP_C9H12N3O8P

367551
type: SpeciesReference
stoichiometry: 1.0
species: 284787

289047
type: Reaction
kinetic law: 382066
product: 382054
reactant: 382042
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acid_peroxisomal_transport

297433
type: LocalParameter
value: -0.071867

297431
type: LocalParameter
value: 0.0

297430
type: LocalParameter
value: 0.0

297429
type: LocalParameter
value: 999999.0

297427
type: LocalParameter
value: 0.0

382054
type: SpeciesReference
stoichiometry: 1.0
species: 285565

285565
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_octanoate__n_C80__C8H15O2

382042
type: SpeciesReference
stoichiometry: 1.0
species: 285562

285562
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_octanoate__n_C80__C8H15O2

284840
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Hexadecenoate__n_C161__C16H29O2

289650
type: Reaction
product: 404022
fast: false
reversible: false
notes: GENE_ASSOCIATION: ( YKL146W or YNL101W ) PROTEIN_ASSOCIATION: ( Avt3-v ) or ( Avt4-v ) SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
kinetic law: 404047
reactant: 403998
reactant: 404010
product: 404034
name: R_L_isoleucine_transport_out_via_proton_symport__vacuolar

404022
type: SpeciesReference
stoichiometry: 1.0
species: 284787

299493
type: LocalParameter
value: 0.0

299491
type: LocalParameter
value: 0.0

299490
type: LocalParameter
value: 0.0

299488
type: LocalParameter
value: 999999.0

299487
type: LocalParameter
value: 0.0

403998
type: SpeciesReference
stoichiometry: 1.0
species: 284805

404010
type: SpeciesReference
stoichiometry: 1.0
species: 285017

285017
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_L_Isoleucine_C6H13NO2

404034
type: SpeciesReference
stoichiometry: 1.0
species: 285008

285008
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Isoleucine_C6H13NO2

288205
type: Reaction
reactant: 368421
reactant: 368409
name: R_2_deoxy_D_arabino_heptulosonate_7_phosphate_synthetase__mitochondrial
product: 368433
notes: GENE_ASSOCIATION: YDR035W PROTEIN_ASSOCIATION: Aro3-m SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.1.2.15
fast: false
kinetic law: 368457
product: 368445
reactant: 368397
reversible: false

368421
type: SpeciesReference
stoichiometry: 1.0
species: 285703

285703
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Phosphoenolpyruvate_C3H2O6P

368409
type: SpeciesReference
stoichiometry: 1.0
species: 284766

368433
type: SpeciesReference
stoichiometry: 1.0
species: 282987

282987
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_Dehydro_3_deoxy_D_arabino_heptonate_7_phosphate_C7H10O10P

294652
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value: 0.0

294649
type: LocalParameter
value: 0.076083

294646
type: LocalParameter
value: 0.0

294643
type: LocalParameter
value: 999999.0

294640
type: LocalParameter
value: 0.0

368445
type: SpeciesReference
stoichiometry: 1.0
species: 285760

368397
type: SpeciesReference
stoichiometry: 1.0
species: 284328

284328
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_D_Erythrose_4_phosphate_C4H7O7P

286285
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_tRNA_Asp__R

290424
type: Reaction
reversible: true
product: 429075
reactant: 429051
notes: GENE_ASSOCIATION: YLR209C PROTEIN_ASSOCIATION: Pnp1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.1
name: R_purine_nucleoside_phosphorylase__Inosine_
kinetic law: 429099
fast: false
reactant: 429063
product: 429087

429075
type: SpeciesReference
stoichiometry: 1.0
species: 284936

284936
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Hypoxanthine_C5H4N4O

429051
type: SpeciesReference
stoichiometry: 1.0
species: 285059

302536
type: LocalParameter
value: 0.0

302534
type: LocalParameter
value: 0.0

302533
type: LocalParameter
value: 0.0

302531
type: LocalParameter
value: 999999.0

302530
type: LocalParameter
value: -999999.0

429063
type: SpeciesReference
stoichiometry: 1.0
species: 285751

429087
type: SpeciesReference
stoichiometry: 1.0
species: 285967

285967
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
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in compartment: 282871
name: M_alpha_D_Ribose_1_phosphate_C5H9O8P

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_Methylthio_5_deoxy_D_ribulose_1_phosphate_C6H11O7PS

288157
type: Reaction
kinetic law: 367406
reactant: 367357
fast: false
product: 367381
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.11
reactant: 367369
reversible: true
product: 367394
name: R_deoxyadenylate_kinase

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294441
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294438
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value: 0.0

294435
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294432
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367357
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species: 283830

367381
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stoichiometry: 1.0
species: 283602

367369
type: SpeciesReference
stoichiometry: 1.0
species: 284094

284094
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_dAMP_C10H12N5O6P

367394
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stoichiometry: 1.0
species: 284085

288776
type: Reaction
kinetic law: 377907
product: 377895
reactant: 377883
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Lysine_exchange

296690
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296688
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296687
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296686
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296684
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377895
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species: 286861

286861
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constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Lysine_C6H15N2O2

377883
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stoichiometry: 1.0
species: 285171

290186
type: Reaction
kinetic law: 421283
product: 421271
reactant: 421259
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Golgi_Apparatus PROTEIN_CLASS:
fast: false
reversible: true
name: R_phosphatidylethanolamine_Golgi_transport__yeast_specific

301642
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301641
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301638
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301637
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301634
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421271
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stoichiometry: 1.0
species: 285682

421259
type: SpeciesReference
stoichiometry: 1.0
species: 285679

285679
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

287584
type: Reaction
reactant: 354457
product: 354505
kinetic law: 354517
notes: GENE_ASSOCIATION: YMR083W PROTEIN_ASSOCIATION: Adh3-m SUBSYSTEM: S_Complex_Alcohol_Metabolism PROTEIN_CLASS:
fast: false
reactant: 354481
reversible: false
name: R_aldehyde_dehydrogenase__tryptophol__NAD___mitochondrial
reactant: 354469
product: 354493

354457
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stoichiometry: 1.0
species: 284796

354505
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stoichiometry: 1.0
species: 285399

292503
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292501
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292499
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292497
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292495
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354481
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stoichiometry: 1.0
species: 285412

354469
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species: 284999

354493
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species: 285047

285047
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Indole_3_ethanol_C10H11NO

284484
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Farnesyl_diphosphate_C15H25O7P2

283968
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Citrate_C6H5O7

287233
type: Reaction
reactant: 347055
fast: false
reactant: 347079
product: 347091
reactant: 347067
product: 347103
kinetic law: 347127
reversible: false
name: R_Aminoacetoneoxygen_oxidoreductase_deaminating__flavin_containing_
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS:
product: 347115

347055
type: SpeciesReference
stoichiometry: 1.0
species: 283482

283482
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Aminoacetone_C3H8NO

347079
type: SpeciesReference
stoichiometry: 1.0
species: 285487

347091
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stoichiometry: 1.0
species: 284747

347067
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stoichiometry: 1.0
species: 284757

347103
type: SpeciesReference
stoichiometry: 1.0
species: 285369

285369
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Methylglyoxal_C3H4O2

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291439
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value: 0.0

291437
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291435
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value: 999999.0

291433
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347115
type: SpeciesReference
stoichiometry: 1.0
species: 285454

289187
type: Reaction
kinetic law: 389346
product: 389334
reactant: 389322
notes: GENE_ASSOCIATION: ( YOR011W or YIL013C ) PROTEIN_ASSOCIATION: ( Aus1 ) or ( Pdr11 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_fecosterol_reversible_transport

297934
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297933
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297931
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297930
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297929
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389334
type: SpeciesReference
stoichiometry: 1.0
species: 284430

389322
type: SpeciesReference
stoichiometry: 1.0
species: 284433

284433
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_fecosterol_C28H46O

283491
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Acetyl_ACP_C13H23N2O8PRS

290138
type: Reaction
kinetic law: 419832
product: 419820
reactant: 419808
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_Phenylacetaldehyde_transport__mitochondrial_

301426
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301425
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301422
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301421
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301418
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419820
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stoichiometry: 1.0
species: 285628

419808
type: SpeciesReference
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species: 285622

285622
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Phenylacetaldehyde_C8H8O

287182
type: Reaction
kinetic law: 346187
product: 346175
reactant: 346163
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_4_aminobutanoate_mitochondrial_transport_via_diffusion

291288
type: LocalParameter
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291286
type: LocalParameter
value: 0.0

291284
type: LocalParameter
value: 0.0

291282
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291280
type: LocalParameter
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346175
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stoichiometry: 1.0
species: 283257

283257
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_4_Aminobutanoate_C4H9NO2

346163
type: SpeciesReference
stoichiometry: 1.0
species: 283251

283251
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Aminobutanoate_C4H9NO2

289934
type: Reaction
kinetic law: 413600
reversible: true
product: 413587
name: R_methylenetetrahydrofolate_dehydrogenase__NADP_
fast: false
product: 413575
reactant: 413563
reactant: 413550
notes: GENE_ASSOCIATION: YGR204W PROTEIN_ASSOCIATION: Ade3 SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 1.5.1.5

300547
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300546
type: LocalParameter
value: 0.076077

300544
type: LocalParameter
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300543
type: LocalParameter
value: 999999.0

300540
type: LocalParameter
value: -999999.0

413587
type: SpeciesReference
stoichiometry: 1.0
species: 285436

413575
type: SpeciesReference
stoichiometry: 1.0
species: 285273

285273
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_10_Methenyltetrahydrofolate_C20H20N7O6

413563
type: SpeciesReference
stoichiometry: 1.0
species: 285421

413550
type: SpeciesReference
stoichiometry: 1.0
species: 285357

285357
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_10_Methylenetetrahydrofolate_C20H21N7O6

285532
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_octadecanoate__n_C180__C18H35O2

284238
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_3_diketo_5_methylthio_1_phosphopentane_C6H9O6PS

283044
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_methylbutyraldehyde_C5H10O

287575
type: Reaction
product: 354287
kinetic law: 354299
name: R_aldehyde_dehydrogenase__2_phenylethanol__NAD___mitochondrial
reactant: 354239
reversible: false
notes: GENE_ASSOCIATION: YMR083W PROTEIN_ASSOCIATION: Adh3-m SUBSYSTEM: S_Complex_Alcohol_Metabolism PROTEIN_CLASS:
reactant: 354263
reactant: 354251
fast: false
product: 354275

354287
type: SpeciesReference
stoichiometry: 1.0
species: 285399

292476
type: LocalParameter
value: -0.067512

292474
type: LocalParameter
value: 0.0

292472
type: LocalParameter
value: 0.0

292470
type: LocalParameter
value: 999999.0

292468
type: LocalParameter
value: 0.0

354239
type: SpeciesReference
stoichiometry: 1.0
species: 284796

354263
type: SpeciesReference
stoichiometry: 1.0
species: 285628

354251
type: SpeciesReference
stoichiometry: 1.0
species: 285412

354275
type: SpeciesReference
stoichiometry: 1.0
species: 283095

283095
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_phenylethanol_C8H10O

285378
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N4_Acetylaminobutanal_C6H11NO2

290540
type: Reaction
fast: false
product: 432900
reversible: false
name: R_Seryl_tRNA_synthetase
reactant: 432888
notes: GENE_ASSOCIATION: ( YHR011W or YDR023W ) PROTEIN_ASSOCIATION: ( Dia4 ) or ( Ses1 ) SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.11
product: 432912
reactant: 432863
reactant: 432876
product: 432924
kinetic law: 432936

432900
type: SpeciesReference
stoichiometry: 1.0
species: 283713

432888
type: SpeciesReference
stoichiometry: 1.0
species: 286345

432912
type: SpeciesReference
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species: 285796

432863
type: SpeciesReference
stoichiometry: 1.0
species: 283830

432876
type: SpeciesReference
stoichiometry: 1.0
species: 286030

286030
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Serine_C3H7NO3

432924
type: SpeciesReference
stoichiometry: 1.0
species: 286039

286039
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Seryl_tRNA_Ser__C3H6NO2R

302942
type: LocalParameter
value: -0.041972

302940
type: LocalParameter
value: 0.0

302939
type: LocalParameter
value: 0.0

302937
type: LocalParameter
value: 999999.0

302936
type: LocalParameter
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283314
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_trans_4_Hydroxy_L_proline_C5H9NO3

290380
type: Reaction
kinetic law: 427766
product: 427754
reactant: 427742
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Golgi_Apparatus PROTEIN_CLASS:
fast: false
reversible: true
name: R_phosphatidylserine_Golgi_transport__yeast_specific

302382
type: LocalParameter
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302380
type: LocalParameter
value: 0.0

302379
type: LocalParameter
value: 0.0

302377
type: LocalParameter
value: 999999.0

302376
type: LocalParameter
value: -999999.0

427754
type: SpeciesReference
stoichiometry: 1.0
species: 285862

427742
type: SpeciesReference
stoichiometry: 1.0
species: 285859

285859
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

288827
type: Reaction
kinetic law: 378530
product: 378518
reactant: 378506
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Ornithine_exchange

296826
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value: -0.034251

296824
type: LocalParameter
value: 0.0

296823
type: LocalParameter
value: 0.0

296822
type: LocalParameter
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296820
type: LocalParameter
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378518
type: SpeciesReference
stoichiometry: 1.0
species: 286912

286912
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Ornithine_C5H13N2O2

378506
type: SpeciesReference
stoichiometry: 1.0
species: 285595

285595
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Ornithine_C5H13N2O2

287119
type: Reaction
reactant: 345160
reversible: true
kinetic law: 345208
fast: false
product: 345184
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
reactant: 345172
product: 345196
name: R_3__4_hydroxyphenyl_pyruvate_mitochondrial_transport_via_proton_symport

345160
type: SpeciesReference
stoichiometry: 1.0
species: 283101

283101
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3__4_Hydroxyphenyl_pyruvate_C9H7O4

291092
type: LocalParameter
value: 0.0

291090
type: LocalParameter
value: 0.0

291087
type: LocalParameter
value: 0.0

291086
type: LocalParameter
value: 999999.0

291085
type: LocalParameter
value: -999999.0

345184
type: SpeciesReference
stoichiometry: 1.0
species: 283104

283104
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_3__4_Hydroxyphenyl_pyruvate_C9H7O4

345172
type: SpeciesReference
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species: 284787

345196
type: SpeciesReference
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species: 284796

284705
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Guanosine_C10H13N5O5

289191
type: Reaction
kinetic law: 389454
notes: GENE_ASSOCIATION: YDR428C PROTEIN_ASSOCIATION: Bna3 SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 3.5.1.9
product: 389430
reactant: 389394
reactant: 389406
fast: false
product: 389442
name: R_N_Formyl_L_kynurenine_amidohydrolase
reversible: false
product: 389418

297947
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value: 0.0

297946
type: LocalParameter
value: 0.0

297944
type: LocalParameter
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297943
type: LocalParameter
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297942
type: LocalParameter
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389430
type: SpeciesReference
stoichiometry: 1.0
species: 284466

389394
type: SpeciesReference
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species: 283437

389406
type: SpeciesReference
stoichiometry: 1.0
species: 284757

389442
type: SpeciesReference
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species: 284787

389418
type: SpeciesReference
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species: 283440

283440
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Kynurenine_C10H12N2O3

285631
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Phenylacetamide_C8H9NO

286561
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_1_3_beta_D_Glucan_C6H10O5

289381
type: Reaction
notes: GENE_ASSOCIATION: YMR300C PROTEIN_ASSOCIATION: Ade4 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.4.2.14
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reversible: false
product: 395615
product: 395639
reactant: 395603
reactant: 395591
product: 395627
reactant: 395579
fast: false
kinetic law: 395651

395615
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species: 284618

395639
type: SpeciesReference
stoichiometry: 1.0
species: 285823

285823
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_Phospho_beta_D_ribosylamine_C5H11NO7P

395603
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species: 285853

395591
type: SpeciesReference
stoichiometry: 1.0
species: 284757

395627
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species: 285796

395579
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species: 284595

298571
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298570
type: LocalParameter
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298568
type: LocalParameter
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298567
type: LocalParameter
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298566
type: LocalParameter
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290332
type: Reaction
reactant: 426196
product: 426220
name: R_phosphoribosylaminoimidazole_synthase
kinetic law: 426268
notes: GENE_ASSOCIATION: YGL234W PROTEIN_ASSOCIATION: Ade5,7 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.3.1
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product: 426232
product: 426256
product: 426244
fast: false
reactant: 426208

426196
type: SpeciesReference
stoichiometry: 1.0
species: 283830

426220
type: SpeciesReference
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species: 283602

302214
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302212
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302211
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302209
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302208
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426232
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stoichiometry: 1.0
species: 283638

283638
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_amino_1__5_phospho_D_ribosyl_imidazole_C8H12N3O7P

426256
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species: 285751

426244
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species: 284787

426208
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species: 284475

287085
type: Reaction
kinetic law: 344689
product: 344677
reactant: 344665
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
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reversible: true
name: R_2_Methylbutanal_transport__extracellular_

290991
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290989
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290987
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290985
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290983
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344677
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species: 283047

283047
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_2_methylbutyraldehyde_C5H10O

344665
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species: 283044

290680
type: Reaction
notes: GENE_ASSOCIATION: ( YBR117C or YPR074C ) PROTEIN_ASSOCIATION: ( Tkl2 ) or ( Tkl1 ) SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 2.2.1.1
reversible: true
reactant: 437645
fast: false
kinetic law: 437693
product: 437681
name: R_transketolase
reactant: 437657
product: 437669

437645
type: SpeciesReference
stoichiometry: 1.0
species: 285973

303442
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value: 0.0

303440
type: LocalParameter
value: 0.263463

303439
type: LocalParameter
value: 0.0

303437
type: LocalParameter
value: 999999.0

303436
type: LocalParameter
value: -999999.0

437681
type: SpeciesReference
stoichiometry: 1.0
species: 286003

286003
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Sedoheptulose_7_phosphate_C7H13O10P

437657
type: SpeciesReference
stoichiometry: 1.0
species: 286525

286525
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Xylulose_5_phosphate_C5H9O8P

437669
type: SpeciesReference
stoichiometry: 1.0
species: 284505

284505
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Glyceraldehyde_3_phosphate_C3H5O6P

285652
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M__R__Pantoate_C6H11O4

289129
type: Reaction
reversible: false
product: 386491
reactant: 386443
kinetic law: 386515
name: R_fatty_acid_synthase__n_C160_
reactant: 386419
product: 386503
fast: false
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.85
reactant: 386407
product: 386455
reactant: 386431
product: 386479
product: 386467

386491
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stoichiometry: 1.0
species: 284828

386443
type: SpeciesReference
stoichiometry: 1.0
species: 286402

297735
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value: 0.0

297733
type: LocalParameter
value: 0.013219

297732
type: LocalParameter
value: 0.0

297731
type: LocalParameter
value: 999999.0

297729
type: LocalParameter
value: 0.0

386419
type: SpeciesReference
stoichiometry: 1.0
species: 285219

285219
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Malonyl_CoA_C24H33N7O19P3S

386503
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stoichiometry: 2.0
species: 285421

386407
type: SpeciesReference
stoichiometry: 3.0
species: 284787

386455
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stoichiometry: 1.0
species: 283992

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stoichiometry: 2.0
species: 285436

386479
type: SpeciesReference
stoichiometry: 1.0
species: 284757

386467
type: SpeciesReference
stoichiometry: 1.0
species: 284013

288244
type: Reaction
reversible: false
fast: false
product: 369314
reactant: 369290
notes: GENE_ASSOCIATION: YOR236W PROTEIN_ASSOCIATION: Dfr1 SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 1.5.1.3
reactant: 369278
kinetic law: 369338
name: R_dihydrofolate_reductase__irreversible_
reactant: 369302
product: 369326

369314
type: SpeciesReference
stoichiometry: 1.0
species: 285421

369290
type: SpeciesReference
stoichiometry: 1.0
species: 284787

369278
type: SpeciesReference
stoichiometry: 1.0
species: 284202

284202
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_7_8_Dihydrofolate_C19H19N7O6

294821
type: LocalParameter
value: 0.0

294818
type: LocalParameter
value: 0.001036

294815
type: LocalParameter
value: 0.0

294812
type: LocalParameter
value: 999999.0

294809
type: LocalParameter
value: 0.0

369302
type: SpeciesReference
stoichiometry: 1.0
species: 285436

369326
type: SpeciesReference
stoichiometry: 1.0
species: 286171

286171
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_6_7_8_Tetrahydrofolate_C19H21N7O6

284211
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Dihydrolipolprotein_H2S2X

287626
type: Reaction
reversible: true
reactant: 355581
reactant: 355569
kinetic law: 355617
product: 355593
fast: false
name: R_allantoinase__reversible_reaction
product: 355605
notes: GENE_ASSOCIATION: YIR027C PROTEIN_ASSOCIATION: Dal1 SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 3.5.2.5

355581
type: SpeciesReference
stoichiometry: 1.0
species: 284757

355569
type: SpeciesReference
stoichiometry: 1.0
species: 283677

283677
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Allantoin_C4H6N4O3

292631
type: LocalParameter
value: 0.0

292629
type: LocalParameter
value: 0.0

292627
type: LocalParameter
value: 0.0

292625
type: LocalParameter
value: 999999.0

292623
type: LocalParameter
value: -999999.0

355593
type: SpeciesReference
stoichiometry: 1.0
species: 283683

283683
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Allantoate_C4H7N4O4

355605
type: SpeciesReference
stoichiometry: 1.0
species: 284787

284827
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_L_Homocysteine_C4H9NO2S

288196
type: Reaction
reactant: 368204
name: R_deoxycytidine_deaminase
product: 368240
notes: GENE_ASSOCIATION: YLR245C PROTEIN_ASSOCIATION: Cdd1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.5.4.14
reactant: 368192
reversible: false
fast: false
product: 368228
reactant: 368216
kinetic law: 368252

368204
type: SpeciesReference
stoichiometry: 1.0
species: 284787

368240
type: SpeciesReference
stoichiometry: 1.0
species: 285454

368192
type: SpeciesReference
stoichiometry: 1.0
species: 284145

284145
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Deoxycytidine_C9H13N3O4

368228
type: SpeciesReference
stoichiometry: 1.0
species: 284307

284307
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Deoxyuridine_C9H12N2O5

368216
type: SpeciesReference
stoichiometry: 1.0
species: 284757

294613
type: LocalParameter
value: -0.011879

294610
type: LocalParameter
value: 0.0

294607
type: LocalParameter
value: 0.0

294604
type: LocalParameter
value: 999999.0

294601
type: LocalParameter
value: 0.0

290082
type: Reaction
kinetic law: 418211
product: 418199
reactant: 418187
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_O2_transport__diffusion_

301179
type: LocalParameter
value: 0.0

301176
type: LocalParameter
value: 1.983954

301175
type: LocalParameter
value: 0.0

301172
type: LocalParameter
value: 999999.0

301171
type: LocalParameter
value: -999999.0

418199
type: SpeciesReference
stoichiometry: 1.0
species: 285493

418187
type: SpeciesReference
stoichiometry: 1.0
species: 285487

288235
type: Reaction
kinetic law: 369157
product: 369145
product: 369133
reactant: 369121
notes: GENE_ASSOCIATION: YJR016C PROTEIN_ASSOCIATION: Ilv3-m SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS:
fast: false
reversible: false
name: R_dihydroxy_acid_dehydratase__2_3_dihydroxy_3_methylpentanoate___mitochondrial

294782
type: LocalParameter
value: 0.0

294779
type: LocalParameter
value: 0.055472

294776
type: LocalParameter
value: 0.0

294773
type: LocalParameter
value: 999999.0

294770
type: LocalParameter
value: 0.0

369145
type: SpeciesReference
stoichiometry: 1.0
species: 284766

369133
type: SpeciesReference
stoichiometry: 1.0
species: 283206

283206
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M__S__3_Methyl_2_oxopentanoate_C6H9O3

369121
type: SpeciesReference
stoichiometry: 1.0
species: 282947

282947
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M__R__2_3_Dihydroxy_3_methylpentanoate_C6H11O4

288719
type: Reaction
kinetic law: 377217
product: 377205
reactant: 377193
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_hexadecenoate__n_C161__exchange

296538
type: LocalParameter
value: -0.311822

296536
type: LocalParameter
value: 0.0

296535
type: LocalParameter
value: 0.0

296534
type: LocalParameter
value: 999999.0

296532
type: LocalParameter
value: 0.0

377205
type: SpeciesReference
stoichiometry: 1.0
species: 286804

286804
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Hexadecenoate__n_C161__C16H29O2

377193
type: SpeciesReference
stoichiometry: 1.0
species: 284840

284292
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_dTTP_C10H13N2O14P3

283383
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_Methylthio_5_deoxy_D_ribose_1_phosphate_C6H11O7PS

286276
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_tRNA_Arg__R

283014
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Hydroxy_hexadecanal_C16H32O2

288004
type: Reaction
product: 364160
reversible: false
reactant: 364148
product: 364172
name: R_chitin_synthase
kinetic law: 364197
fast: false
product: 364185
notes: GENE_ASSOCIATION: ( YNL192W or YBR038W or YBR023C ) PROTEIN_ASSOCIATION: ( Chs1 ) or ( Chs2 ) or ( Chs3 ) SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 2.4.1.16

364160
type: SpeciesReference
stoichiometry: 1.0
species: 283944

283944
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Chitin__monomer__C8H13NO5

364148
type: SpeciesReference
stoichiometry: 1.0
species: 286444

286444
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

364172
type: SpeciesReference
stoichiometry: 1.0
species: 284787

293813
type: LocalParameter
value: -0.08335

293811
type: LocalParameter
value: 0.0

293809
type: LocalParameter
value: 0.0

293807
type: LocalParameter
value: 999999.0

293804
type: LocalParameter
value: 0.0

364185
type: SpeciesReference
stoichiometry: 1.0
species: 286438

283299
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_4_Hydroxy_2_oxoglutarate_C5H4O6

288139
type: Reaction
fast: false
notes: GENE_ASSOCIATION: YLR245C PROTEIN_ASSOCIATION: Cdd1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 3.5.4.5
name: R_cytidine_deaminase
reactant: 366961
product: 367009
reversible: false
reactant: 366973
kinetic law: 367021
reactant: 366985
product: 366997

366961
type: SpeciesReference
stoichiometry: 1.0
species: 284073

284073
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Cytidine_C9H13N3O5

367009
type: SpeciesReference
stoichiometry: 1.0
species: 286483

286483
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Uridine_C9H12N2O6

366973
type: SpeciesReference
stoichiometry: 1.0
species: 284787

294366
type: LocalParameter
value: -0.023758

294363
type: LocalParameter
value: 0.0

294360
type: LocalParameter
value: 0.0

294357
type: LocalParameter
value: 999999.0

294354
type: LocalParameter
value: 0.0

366985
type: SpeciesReference
stoichiometry: 1.0
species: 284757

366997
type: SpeciesReference
stoichiometry: 1.0
species: 285454

290168
type: Reaction
reactant: 420677
product: 420689
kinetic law: 420713
fast: false
name: R_3__5__cyclic_nucleotide_phosphodiesterase
product: 420701
reactant: 420665
reversible: false
notes: GENE_ASSOCIATION: YOR360C PROTEIN_ASSOCIATION: Pde2 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 3.1.4.17

420677
type: SpeciesReference
stoichiometry: 1.0
species: 284757

420689
type: SpeciesReference
stoichiometry: 1.0
species: 283983

301561
type: LocalParameter
value: 0.0

301560
type: LocalParameter
value: 0.0

301557
type: LocalParameter
value: 0.0

301556
type: LocalParameter
value: 999999.0

301553
type: LocalParameter
value: 0.0

420701
type: SpeciesReference
stoichiometry: 1.0
species: 284787

420665
type: SpeciesReference
stoichiometry: 1.0
species: 283110

283110
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3__5__Cyclic_CMP_C9H11N3O7P

285586
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_hydroxide_ion_HO

282902
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_1_3_Diaminopropane_C3H12N2

287005
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Thymine_C5H6N2O2

289010
type: Reaction
name: R_fatty_acyl_CoA_peroxisomal_transport_via_ABC_system
product: 381054
reversible: false
reactant: 380981
reactant: 381005
fast: false
product: 381042
kinetic law: 381067
reactant: 380993
notes: GENE_ASSOCIATION: ( YPL147W and YKL188C ) PROTEIN_ASSOCIATION: ( Pxa1-p and Pxa2-p ) SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
product: 381017
product: 381030

381054
type: SpeciesReference
stoichiometry: 1.0
species: 285778

380981
type: SpeciesReference
stoichiometry: 1.0
species: 285775

381005
type: SpeciesReference
stoichiometry: 1.0
species: 284778

381042
type: SpeciesReference
stoichiometry: 1.0
species: 285772

297308
type: LocalParameter
value: -0.016037

297306
type: LocalParameter
value: 0.0

297305
type: LocalParameter
value: 0.0

297304
type: LocalParameter
value: 999999.0

297302
type: LocalParameter
value: 0.0

380993
type: SpeciesReference
stoichiometry: 1.0
species: 283845

381017
type: SpeciesReference
stoichiometry: 1.0
species: 283617

381030
type: SpeciesReference
stoichiometry: 1.0
species: 284808

284903
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Histidine_C6H9N3O2

289145
type: Reaction
fast: false
product: 387465
kinetic law: 387514
name: R_fatty_acid_synthase__n_C181_
product: 387477
product: 387453
notes: GENE_ASSOCIATION: YJL196C PROTEIN_ASSOCIATION: Elo1 SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.85
reactant: 387393
product: 387489
reactant: 387441
reversible: false
reactant: 387417
product: 387502
reactant: 387405
reactant: 387429

387465
type: SpeciesReference
stoichiometry: 1.0
species: 284013

297791
type: LocalParameter
value: 0.0

297789
type: LocalParameter
value: 0.00532

297788
type: LocalParameter
value: 0.0

297787
type: LocalParameter
value: 999999.0

297785
type: LocalParameter
value: 0.0

387477
type: SpeciesReference
stoichiometry: 3.0
species: 284757

387453
type: SpeciesReference
stoichiometry: 1.0
species: 283992

387393
type: SpeciesReference
stoichiometry: 4.0
species: 284787

387489
type: SpeciesReference
stoichiometry: 3.0
species: 285421

387441
type: SpeciesReference
stoichiometry: 1.0
species: 285487

387417
type: SpeciesReference
stoichiometry: 1.0
species: 285219

387502
type: SpeciesReference
stoichiometry: 1.0
species: 285538

387405
type: SpeciesReference
stoichiometry: 1.0
species: 284828

387429
type: SpeciesReference
stoichiometry: 3.0
species: 285436

284358
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Ergosterol_C28H44O

287140
type: Reaction
name: R_3_Dehydrosphinganine_reductase
reactant: 345509
notes: GENE_ASSOCIATION: YBR265W PROTEIN_ASSOCIATION: Tsc10 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS: 1.1.1.102
fast: false
product: 345545
product: 345533
reactant: 345497
reversible: false
kinetic law: 345557
reactant: 345521

345509
type: SpeciesReference
stoichiometry: 1.0
species: 284787

345545
type: SpeciesReference
stoichiometry: 1.0
species: 286069

345533
type: SpeciesReference
stoichiometry: 1.0
species: 285421

345497
type: SpeciesReference
stoichiometry: 1.0
species: 283152

283152
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3_Dehydrosphinganine_C18H38NO2

291157
type: LocalParameter
value: 0.0

291155
type: LocalParameter
value: 0.0

291153
type: LocalParameter
value: 0.0

291151
type: LocalParameter
value: 999999.0

291149
type: LocalParameter
value: 0.0

345521
type: SpeciesReference
stoichiometry: 1.0
species: 285436

288857
type: Reaction
kinetic law: 378892
product: 378880
reactant: 378868
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Proline_exchange

296906
type: LocalParameter
value: -0.033063

296904
type: LocalParameter
value: 0.0

296903
type: LocalParameter
value: 0.0

296902
type: LocalParameter
value: 999999.0

296900
type: LocalParameter
value: 0.0

378880
type: SpeciesReference
stoichiometry: 1.0
species: 286942

286942
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Proline_C5H9NO2

378868
type: SpeciesReference
stoichiometry: 1.0
species: 285844

287275
type: Reaction
product: 348035
reversible: false
name: R_acetyl_CoA_acyltransferase__hexadecanoyl_CoA___peroxisomal
notes: GENE_ASSOCIATION: YIL160C PROTEIN_ASSOCIATION: Pot1-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 2.3.1.16
reactant: 348009
fast: false
product: 348048
kinetic law: 348061
reactant: 348022

348035
type: SpeciesReference
stoichiometry: 1.0
species: 283530

348009
type: SpeciesReference
stoichiometry: 1.0
species: 283218

283218
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_3_Oxooctadecanoyl_CoA_C39H64N7O18P3S

348048
type: SpeciesReference
stoichiometry: 1.0
species: 285778

291566
type: LocalParameter
value: 0.0

291564
type: LocalParameter
value: 0.0

291562
type: LocalParameter
value: 0.0

291560
type: LocalParameter
value: 999999.0

291558
type: LocalParameter
value: 0.0

348022
type: SpeciesReference
stoichiometry: 1.0
species: 284025

289756
type: Reaction
kinetic law: 407674
product: 407661
reactant: 407649
notes: GENE_ASSOCIATION: YHR072W PROTEIN_ASSOCIATION: Erg7 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS: 5.4.99.7
fast: false
reversible: false
name: R_lanosterol_synthase

299869
type: LocalParameter
value: 0.0

299867
type: LocalParameter
value: 6.33E-4

299866
type: LocalParameter
value: 0.0

299864
type: LocalParameter
value: 999999.0

299863
type: LocalParameter
value: 0.0

407661
type: SpeciesReference
stoichiometry: 1.0
species: 285128

285128
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Lanosterol_C30H50O

407649
type: SpeciesReference
stoichiometry: 1.0
species: 283464

283464
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M__S__Squalene_2_3_epoxide_C30H50O

290634
type: Reaction
fast: false
reactant: 436056
product: 436093
product: 436105
reversible: true
kinetic law: 436117
product: 436080
name: R_TetrahydrofolateL_glutamate_gamma_ligase__ADP_forming_
reactant: 436032
notes: GENE_ASSOCIATION: ( YKL132C or YOR241W or YMR113W ) PROTEIN_ASSOCIATION: ( Rma1 ) or ( Met7 ) or ( Fol3 ) SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 6.3.2.17
reactant: 436044
product: 436068

436056
type: SpeciesReference
stoichiometry: 1.0
species: 286171

436093
type: SpeciesReference
stoichiometry: 1.0
species: 285751

436105
type: SpeciesReference
stoichiometry: 1.0
species: 286177

286177
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Tetrahydrofolyl_Glu_2__C24H27N8O9

303281
type: LocalParameter
value: 0.0

303279
type: LocalParameter
value: 0.0

303278
type: LocalParameter
value: 0.0

303276
type: LocalParameter
value: 999999.0

303275
type: LocalParameter
value: -999999.0

436080
type: SpeciesReference
stoichiometry: 1.0
species: 284787

436032
type: SpeciesReference
stoichiometry: 1.0
species: 283830

436044
type: SpeciesReference
stoichiometry: 1.0
species: 284618

436068
type: SpeciesReference
stoichiometry: 1.0
species: 283602

286939
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M__R__Pantothenate_C9H16NO5

284541
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Glucosamine_1_phosphate_C6H13NO8P

290362
type: Reaction
product: 427211
reactant: 427173
product: 427199
reactant: 427186
fast: false
notes: GENE_ASSOCIATION: YNL169C PROTEIN_ASSOCIATION: Psd1-m SUBSYSTEM: S_Phospholipid_Biosynthesis PROTEIN_CLASS: 4.1.1.65
reversible: false
kinetic law: 427223
name: R_phosphatidylserine_decarboxylase__yeast_specific__mitochondrial

427211
type: SpeciesReference
stoichiometry: 0.01
species: 285685

285685
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

427173
type: SpeciesReference
stoichiometry: 1.0
species: 284796

427199
type: SpeciesReference
stoichiometry: 1.0
species: 284001

427186
type: SpeciesReference
stoichiometry: 0.01
species: 285865

302319
type: LocalParameter
value: 0.0

302317
type: LocalParameter
value: 0.003023

302316
type: LocalParameter
value: 0.0

302314
type: LocalParameter
value: 999999.0

302313
type: LocalParameter
value: 0.0

283248
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Acetamidobutanoate_C6H10NO3

287521
type: Reaction
name: R_alkaline_phosphatase__Dihydroneopterin_
fast: false
kinetic law: 353042
notes: GENE_ASSOCIATION: YDR481C PROTEIN_ASSOCIATION: Pho8 SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 3.1.3.1
product: 353018
reversible: false
reactant: 352994
reactant: 352982
product: 353030
product: 353006

292306
type: LocalParameter
value: -0.214216

292304
type: LocalParameter
value: 0.0

292302
type: LocalParameter
value: 0.0

292300
type: LocalParameter
value: 999999.0

292298
type: LocalParameter
value: 0.0

353018
type: SpeciesReference
stoichiometry: 2.0
species: 284787

352994
type: SpeciesReference
stoichiometry: 3.0
species: 284757

352982
type: SpeciesReference
stoichiometry: 1.0
species: 283632

283632
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Amino_4_hydroxy_6__erythro_1_2_3_trihydroxypropyl_dihydropteridine_triphosphate_C9H12N5O13P3

353030
type: SpeciesReference
stoichiometry: 3.0
species: 285751

353006
type: SpeciesReference
stoichiometry: 1.0
species: 284214

287656
type: Reaction
reactant: 356136
name: R_Adenosine_monophosphate_deaminase
product: 356148
product: 356160
kinetic law: 356172
fast: false
reactant: 356112
reversible: false
notes: GENE_ASSOCIATION: YML035C PROTEIN_ASSOCIATION: Amd1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS:
reactant: 356124

356136
type: SpeciesReference
stoichiometry: 1.0
species: 284757

356148
type: SpeciesReference
stoichiometry: 1.0
species: 285029

285029
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_IMP_C10H11N4O8P

356160
type: SpeciesReference
stoichiometry: 1.0
species: 285454

292721
type: LocalParameter
value: -0.016037

292719
type: LocalParameter
value: 0.0

292717
type: LocalParameter
value: 0.0

292715
type: LocalParameter
value: 999999.0

292713
type: LocalParameter
value: 0.0

356112
type: SpeciesReference
stoichiometry: 1.0
species: 283713

356124
type: SpeciesReference
stoichiometry: 1.0
species: 284787

283227
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_3_Hexaprenyl_4_hydroxybenzoate_C37H53O3

284400
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Fructose_2_6_bisphosphate_C6H10O12P2

290590
type: Reaction
reversible: false
reactant: 434499
kinetic law: 434560
name: R_Squalene_epoxidase__endoplasmic_reticular__NAD_
reactant: 434487
product: 434548
fast: false
product: 434523
reactant: 434475
notes: GENE_ASSOCIATION: ( ( YIL043C and YNL111C and YGR175C ) or ( YNL111C and YGR175C and YKL150W ) ) PROTEIN_ASSOCIATION: ( Cbr1 and Cyb5 and Erg1-er ) or ( Cyb5 and Erg1-er and Mcr1-m ) SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS: 1.14.99.7
reactant: 434511
product: 434536

434499
type: SpeciesReference
stoichiometry: 1.0
species: 285496

285496
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_O2_O2

303117
type: LocalParameter
value: 0.0

303115
type: LocalParameter
value: 0.0

303114
type: LocalParameter
value: 0.0

303112
type: LocalParameter
value: 999999.0

303111
type: LocalParameter
value: 0.0

434487
type: SpeciesReference
stoichiometry: 1.0
species: 285415

285415
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873

434548
type: SpeciesReference
stoichiometry: 1.0
species: 285405

285405
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873

434523
type: SpeciesReference
stoichiometry: 1.0
species: 283467

283467
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M__S__Squalene_2_3_epoxide_C30H50O

434475
type: SpeciesReference
stoichiometry: 1.0
species: 284802

434511
type: SpeciesReference
stoichiometry: 1.0
species: 286090

434536
type: SpeciesReference
stoichiometry: 1.0
species: 284772

284772
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_H2O_H2O

286957
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Riboflavin_C17H20N4O6

287054
type: Reaction
product: 343936
product: 343961
fast: false
kinetic law: 343973
reversible: false
notes: GENE_ASSOCIATION: ( ( ( YCR034W and YGR032W ) and YLR343W ) or ( ( YCR034W and YGR032W ) and YMR215W ) or ( ( YCR034W and YMR306W ) and YMR215W ) or ( ( YCR034W and YLR342W ) and YOL132W ) or ( ( YCR034W and YMR306W ) and YOL132W ) or ( ( YCR034W and YGR032W ) and YOL030W ) or ( ( YCR034W and YLR342W ) and YOL030W ) or ( ( YCR034W and YMR306W ) and YOL030W ) or ( ( YCR034W and YLR342W ) and YLR343W ) or ( ( YCR034W and YMR306W ) and YLR343W ) or ( ( YCR034W and YGR032W ) and YOL132W ) or ( ( YCR034W and YLR342W ) and YMR215W ) or ( ( YCR034W and YGR032W ) and YMR307W ) or ( ( YCR034W and YLR342W ) and YMR307W ) or ( ( YCR034W and YMR306W ) and YMR307W ) ) PROTEIN_ASSOCIATION: ( Bdgs1 and Gas2 ) or ( Bdgs1 and Gas3 ) or ( Bdgs3 and Gas3 ) or ( Bdgs2 and Gas4 ) or ( Bdgs3 and Gas4 ) or ( Bdgs1 and Gas5 ) or ( Bdgs2 and Gas5 ) or ( Bdgs3 and Gas5 ) or ( Bdgs2 and Gas2 ) or ( Bdgs3 and Gas2 ) or ( Bdgs1 and Gas4 ) or ( Bdgs2 and Gas3 ) or ( Bdgs1 and Gas1 ) or ( Bdgs2 and Gas1 ) or ( Bdgs3 and Gas1 ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.34
reactant: 343924
name: R_1_3_beta_glucan_synthase
product: 343948

343936
type: SpeciesReference
stoichiometry: 1.0
species: 282896

282896
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_1_3_beta_D_Glucan_C6H10O5

343961
type: SpeciesReference
stoichiometry: 1.0
species: 286438

290874
type: LocalParameter
value: 0.0

290872
type: LocalParameter
value: 0.32667

290870
type: LocalParameter
value: 0.0

290868
type: LocalParameter
value: 999999.0

290866
type: LocalParameter
value: 0.0

343924
type: SpeciesReference
stoichiometry: 1.0
species: 286447

286447
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_UDPglucose_C15H22N2O17P2

343948
type: SpeciesReference
stoichiometry: 1.0
species: 284787

289806
type: Reaction
kinetic law: 409289
product: 409277
product: 409265
reactant: 409253
notes: GENE_ASSOCIATION: YPR006C PROTEIN_ASSOCIATION: Icl2-m SUBSYSTEM: S_Anaplerotic_reactions PROTEIN_CLASS: 4.1.3.30
fast: false
reversible: false
name: R_methylisocitrate_lyase

300048
type: LocalParameter
value: 0.0

300047
type: LocalParameter
value: 0.0

300046
type: LocalParameter
value: 0.0

300045
type: LocalParameter
value: 999999.0

300043
type: LocalParameter
value: 0.0

409277
type: SpeciesReference
stoichiometry: 1.0
species: 286111

286111
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Succinate_C4H4O4

409265
type: SpeciesReference
stoichiometry: 1.0
species: 285949

409253
type: SpeciesReference
stoichiometry: 1.0
species: 285312

285312
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_methylisocitrate_C7H7O7

285149
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_L_Leucine_C6H13NO2

286624
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_2_Oxoglutarate_C5H4O5

290040
type: Reaction
notes: GENE_ASSOCIATION: YFR047C PROTEIN_ASSOCIATION: Bna6 SUBSYSTEM: S_NAD_Biosynthesis PROTEIN_CLASS: 2.4.2.19
product: 416899
reactant: 416875
name: R_nicotinate_nucleotide_diphosphorylase__carboxylating_
reactant: 416862
product: 416923
product: 416911
fast: false
kinetic law: 416935
reactant: 416887
reversible: false

416899
type: SpeciesReference
stoichiometry: 1.0
species: 283992

416875
type: SpeciesReference
stoichiometry: 1.0
species: 285853

416862
type: SpeciesReference
stoichiometry: 2.0
species: 284787

416923
type: SpeciesReference
stoichiometry: 1.0
species: 285796

416911
type: SpeciesReference
stoichiometry: 1.0
species: 285469

285469
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Nicotinate_D_ribonucleotide_C11H12NO9P

301003
type: LocalParameter
value: 0.0

301002
type: LocalParameter
value: 0.0

301000
type: LocalParameter
value: 0.0

300999
type: LocalParameter
value: 999999.0

300998
type: LocalParameter
value: 0.0

416887
type: SpeciesReference
stoichiometry: 1.0
species: 285961

288160
type: Reaction
name: R_deoxyadenosine_transport_in_via_proton_symport
fast: false
kinetic law: 367466
reactant: 367418
product: 367454
product: 367442
reactant: 367430
reversible: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:

294457
type: LocalParameter
value: 0.0

294454
type: LocalParameter
value: 0.0

294451
type: LocalParameter
value: 0.0

294448
type: LocalParameter
value: 999999.0

294445
type: LocalParameter
value: 0.0

367418
type: SpeciesReference
stoichiometry: 1.0
species: 284082

284082
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Deoxyadenosine_C10H13N5O3

367454
type: SpeciesReference
stoichiometry: 1.0
species: 284787

367442
type: SpeciesReference
stoichiometry: 1.0
species: 284079

367430
type: SpeciesReference
stoichiometry: 1.0
species: 284790

290412
type: Reaction
name: R_purine_nucleoside_phosphorylase__Adenosine_
notes: GENE_ASSOCIATION: YLR209C PROTEIN_ASSOCIATION: Pnp1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.1
reactant: 428700
reversible: true
product: 428712
product: 428724
reactant: 428688
kinetic law: 428736
fast: false

428700
type: SpeciesReference
stoichiometry: 1.0
species: 285751

428712
type: SpeciesReference
stoichiometry: 1.0
species: 283584

283584
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Adenine_C5H5N5

428724
type: SpeciesReference
stoichiometry: 1.0
species: 285967

428688
type: SpeciesReference
stoichiometry: 1.0
species: 283593

302494
type: LocalParameter
value: 0.0

302492
type: LocalParameter
value: 0.0

302491
type: LocalParameter
value: 0.0

302489
type: LocalParameter
value: 999999.0

302488
type: LocalParameter
value: -999999.0

289041
type: Reaction
reactant: 381898
product: 381946
fast: false
product: 381934
kinetic law: 381958
reactant: 381874
product: 381910
product: 381922
reactant: 381886
name: R_fatty_acyl_CoA_peroxisomal_transport_via_ABC_system
reversible: false
notes: GENE_ASSOCIATION: ( YPL147W and YKL188C ) PROTEIN_ASSOCIATION: ( Pxa1-p and Pxa2-p ) SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:

381898
type: SpeciesReference
stoichiometry: 1.0
species: 284778

381946
type: SpeciesReference
stoichiometry: 1.0
species: 285772

381934
type: SpeciesReference
stoichiometry: 1.0
species: 285559

285559
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

297412
type: LocalParameter
value: 0.0

297410
type: LocalParameter
value: 0.0

297409
type: LocalParameter
value: 0.0

297408
type: LocalParameter
value: 999999.0

297407
type: LocalParameter
value: 0.0

381874
type: SpeciesReference
stoichiometry: 1.0
species: 285556

381910
type: SpeciesReference
stoichiometry: 1.0
species: 283617

381922
type: SpeciesReference
stoichiometry: 1.0
species: 284808

381886
type: SpeciesReference
stoichiometry: 1.0
species: 283845

284406
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

286234
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Oxidized_thioredoxin_X

286900
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Oxaloacetate_C4H2O5

289175
type: Reaction
kinetic law: 388849
reactant: 388813
product: 388837
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.2.2.1
name: R_formate__dehydrogenase__cytosolicmitochondrial
reactant: 388789
reversible: false
fast: false
reactant: 388801
product: 388825

297895
type: LocalParameter
value: -0.002178

297894
type: LocalParameter
value: 0.0

297892
type: LocalParameter
value: 0.0

297891
type: LocalParameter
value: 999999.0

297889
type: LocalParameter
value: 0.0

388813
type: SpeciesReference
stoichiometry: 1.0
species: 285955

388837
type: SpeciesReference
stoichiometry: 1.0
species: 285958

388789
type: SpeciesReference
stoichiometry: 1.0
species: 284466

388801
type: SpeciesReference
stoichiometry: 1.0
species: 284787

388825
type: SpeciesReference
stoichiometry: 1.0
species: 283992

286816
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_isoamyl_acetate_C7H14O2

289810
type: Reaction
reactant: 409386
kinetic law: 409435
reactant: 409398
reversible: true
notes: GENE_ASSOCIATION: ( YKL182W and YPL231W ) PROTEIN_ASSOCIATION: Fas SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.39
product: 409411
name: R_Malonyl_CoA_ACP_transacylase
fast: false
product: 409423

409386
type: SpeciesReference
stoichiometry: 1.0
species: 283416

300072
type: LocalParameter
value: 0.0

300071
type: LocalParameter
value: 0.0

300069
type: LocalParameter
value: 0.0

300068
type: LocalParameter
value: 999999.0

300066
type: LocalParameter
value: -999999.0

409398
type: SpeciesReference
stoichiometry: 1.0
species: 285219

409411
type: SpeciesReference
stoichiometry: 1.0
species: 284013

409423
type: SpeciesReference
stoichiometry: 1.0
species: 285201

285201
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

290126
type: Reaction
reversible: true
notes: GENE_ASSOCIATION: ( YML106W or YMR271C ) PROTEIN_ASSOCIATION: ( Ura5 ) or ( Ura10 ) SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.4.2.10
product: 419469
kinetic law: 419481
reactant: 419445
name: R_orotate_phosphoribosyltransferase
reactant: 419433
fast: false
product: 419457

419469
type: SpeciesReference
stoichiometry: 1.0
species: 285853

301372
type: LocalParameter
value: 0.0

301371
type: LocalParameter
value: -0.031838

301368
type: LocalParameter
value: 0.0

301367
type: LocalParameter
value: 999999.0

301364
type: LocalParameter
value: -999999.0

419445
type: SpeciesReference
stoichiometry: 1.0
species: 285796

419433
type: SpeciesReference
stoichiometry: 1.0
species: 285601

285601
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Orotidine_5__phosphate_C10H10N2O11P

419457
type: SpeciesReference
stoichiometry: 1.0
species: 285604

283296
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_4_Hydroxy_2_oxoglutarate_C5H4O6

290714
type: Reaction
kinetic law: 438722
product: 438710
reactant: 438698
reactant: 438686
notes: GENE_ASSOCIATION: ( YDR001C or YBR001C ) PROTEIN_ASSOCIATION: ( Nth1 ) or ( Nth2 ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.28
fast: false
reversible: false
name: R_alpha_alpha_trehalase

303561
type: LocalParameter
value: -0.035637

303560
type: LocalParameter
value: 0.0

303558
type: LocalParameter
value: 0.0

303557
type: LocalParameter
value: 999999.0

303555
type: LocalParameter
value: 0.0

438710
type: SpeciesReference
stoichiometry: 2.0
species: 284586

284586
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Glucose_C6H12O6

438698
type: SpeciesReference
stoichiometry: 1.0
species: 286258

286258
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Trehalose_C12H22O11

438686
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species: 284757

289786
type: Reaction
reversible: false
fast: false
name: R_malate_synthase
reactant: 408710
notes: GENE_ASSOCIATION: ( YIR031C or YNL117W ) PROTEIN_ASSOCIATION: ( Dal7-p ) or ( Mls1-p ) SUBSYSTEM: S_Anaplerotic_reactions PROTEIN_CLASS: 4.1.3.2
product: 408747
reactant: 408686
product: 408735
product: 408723
reactant: 408698
kinetic law: 408759

408710
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stoichiometry: 1.0
species: 284778

408747
type: SpeciesReference
stoichiometry: 1.0
species: 285216

285216
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_L_Malate_C4H4O5

408686
type: SpeciesReference
stoichiometry: 1.0
species: 283530

408735
type: SpeciesReference
stoichiometry: 1.0
species: 284808

408723
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stoichiometry: 1.0
species: 284025

408698
type: SpeciesReference
stoichiometry: 1.0
species: 284654

284654
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Glyoxylate_C2H1O3

299977
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299976
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value: 0.0

299975
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value: 0.0

299973
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value: 999999.0

299972
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value: 0.0

285053
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_myo_Inositol_C6H12O6

283062
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_Methylcitrate_C7H7O7

287698
type: Reaction
kinetic law: 357005
product: 356993
product: 356981
reactant: 356969
notes: GENE_ASSOCIATION: YHR018C PROTEIN_ASSOCIATION: Arg4 SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 4.3.2.1
fast: false
reversible: true
name: R_argininosuccinate_lyase

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value: 0.0

292845
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value: 0.04626

292843
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value: 0.0

292841
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value: 999999.0

292839
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value: -999999.0

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stoichiometry: 1.0
species: 284493

356981
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stoichiometry: 1.0
species: 283761

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species: 283773

283773
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N_omega___L_Arginino_succinate_C10H17N4O6

287075
type: Reaction
product: 344469
name: R_2_Hexaprenyl_6_methoxyphenol_monooxygenase__mitochondrial
kinetic law: 344493
reactant: 344445
product: 344481
reactant: 344457
notes: GENE_ASSOCIATION: ( YOL096C and YDR204W and YML110C and YGR255C and YOR125C and YGL119W and YLR201C ) PROTEIN_ASSOCIATION: ( Coq3-m and Coq4-m and Coq5-m and Coq6-m and Coq7-m and Coq8-m and Coq9-m ) SUBSYSTEM: S_Quinone_Biosynthesis PROTEIN_CLASS:
reversible: false
fast: false

344469
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stoichiometry: 1.0
species: 283017

283017
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_Hexaprenyl_6_methoxy_1_4_benzoquinone_C37H54O3

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value: 0.0

290953
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value: 0.0

290951
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value: 0.0

290949
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290947
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value: 0.0

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stoichiometry: 1.0
species: 283020

344481
type: SpeciesReference
stoichiometry: 1.0
species: 284766

344457
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stoichiometry: 1.0
species: 285493

287122
type: Reaction
reactant: 345220
product: 345256
kinetic law: 345268
name: R_3__4_hydroxyphenyl_pyruvate_peroxisomal_transport_via_proton_symport
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
product: 345244
fast: false
reactant: 345232
reversible: true

345220
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stoichiometry: 1.0
species: 283101

345256
type: SpeciesReference
stoichiometry: 1.0
species: 284808

291100
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291098
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value: 0.0

291095
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value: 0.0

291094
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value: 999999.0

291093
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value: -999999.0

345244
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stoichiometry: 1.0
species: 283107

283107
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_3__4_Hydroxyphenyl_pyruvate_C9H7O4

345232
type: SpeciesReference
stoichiometry: 1.0
species: 284787

290848
type: Reaction
reactant: 443706
reactant: 443596
reactant: 443223
reactant: 443668
reactant: 443332
reactant: 443718
reactant: 443404
reactant: 443344
reactant: 443488
reactant: 443608
reactant: 443307
reactant: 443754
reactant: 443416
product: 443802
reactant: 443127
reactant: 443766
reactant: 443428
reactant: 443681
reactant: 443139
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS:
reversible: false
reactant: 443271
reactant: 443620
name: R_biomass_published
reactant: 443560
reactant: 443283
reactant: 443572
reactant: 443295
kinetic law: 443814
reactant: 443500
reactant: 443730
reactant: 443512
reactant: 443452
reactant: 443742
reactant: 443524
reactant: 443464
reactant: 443235
reactant: 443694
reactant: 443536
reactant: 443476
reactant: 443247
reactant: 443356
reactant: 443548
reactant: 443259
reactant: 443368
fast: false
reactant: 443151
reactant: 443163
product: 443778
reactant: 443175
reactant: 443380
reactant: 443187
reactant: 443392
reactant: 443632
product: 443790
reactant: 443319
reactant: 443199
reactant: 443644
reactant: 443584
reactant: 443440
reactant: 443211
reactant: 443656

443706
type: SpeciesReference
stoichiometry: 6.6E-5
species: 286267

443596
type: SpeciesReference
stoichiometry: 5.3E-5
species: 285898

443223
type: SpeciesReference
stoichiometry: 1.0E-6
species: 283944

443668
type: SpeciesReference
stoichiometry: 1.0E-6
species: 286201

443332
type: SpeciesReference
stoichiometry: 1.0E-6
species: 284406

443718
type: SpeciesReference
stoichiometry: 0.0284
species: 286372

286372
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Tryptophan_C11H12N2O2

443404
type: SpeciesReference
stoichiometry: 1.0E-6
species: 284720

284720
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Reduced_glutathione_C10H16N3O6S

443344
type: SpeciesReference
stoichiometry: 0.1054
species: 284595

443488
type: SpeciesReference
stoichiometry: 0.0507
species: 285264

443608
type: SpeciesReference
stoichiometry: 1.0E-6
species: 285955

443307
type: SpeciesReference
stoichiometry: 0.0036
species: 284286

284286
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_dTMP_C10H13N2O8P

443754
type: SpeciesReference
stoichiometry: 0.2646
species: 286495

443416
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stoichiometry: 59.276
species: 284757

443802
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species: 285751

443127
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stoichiometry: 1.1348
species: 282896

443766
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stoichiometry: 0.0015
species: 286549

443428
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stoichiometry: 0.0663
species: 284897

443681
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stoichiometry: 0.1914
species: 286204

443139
type: SpeciesReference
stoichiometry: 0.4588
species: 283659

443271
type: SpeciesReference
stoichiometry: 0.0036
species: 284094

443620
type: SpeciesReference
stoichiometry: 9.9E-4
species: 285985

443560
type: SpeciesReference
stoichiometry: 1.0E-6
species: 285733

285733
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: M_Protoheme_C34H30FeN4O4

443283
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species: 284139

284139
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: M_dCMP_C9H12N3O7P

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species: 285841

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type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Proline_C5H9NO2

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species: 284181

284181
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_dGMP_C10H12N5O7P

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304029
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value: 0.0

304027
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304026
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304024
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443500
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stoichiometry: 1.0E-6
species: 285396

443730
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stoichiometry: 0.102
species: 286417

286417
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Tyrosine_C9H11NO3

443512
type: SpeciesReference
stoichiometry: 6.0E-6
species: 285613

443452
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stoichiometry: 0.2964
species: 285140

285140
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Leucine_C6H13NO2

443742
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stoichiometry: 0.0599
species: 286456

443524
type: SpeciesReference
stoichiometry: 6.0E-5
species: 285670

443464
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stoichiometry: 0.2862
species: 285168

443235
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stoichiometry: 0.0447
species: 283983

443694
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stoichiometry: 0.0234
species: 286258

443536
type: SpeciesReference
stoichiometry: 4.5E-5
species: 285679

443476
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stoichiometry: 0.8079
species: 285249

285249
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Mannan_C6H10O5

443247
type: SpeciesReference
stoichiometry: 1.0E-6
species: 284013

443356
type: SpeciesReference
stoichiometry: 0.3018
species: 284618

443548
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species: 285718

443259
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stoichiometry: 0.0066
species: 284058

443368
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stoichiometry: 0.2904
species: 284657

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species: 283713

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species: 283761

443778
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species: 283602

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species: 283782

283782
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Asparagine_C4H8N2O3

443380
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species: 284681

284681
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_glycogen_C6H10O5

443187
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species: 283800

443392
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species: 284690

284690
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_GMP_C10H12N5O8P

443632
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species: 286030

443790
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stoichiometry: 58.70001
species: 284787

443319
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stoichiometry: 7.0E-4
species: 284352

284352
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ergosterol_C28H44O

443199
type: SpeciesReference
stoichiometry: 59.276
species: 283830

443644
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stoichiometry: 0.02
species: 286057

286057
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Sulfate_O4S

443584
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stoichiometry: 1.7E-5
species: 285859

443440
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stoichiometry: 0.1927
species: 285008

443211
type: SpeciesReference
stoichiometry: 1.0E-6
species: 283866

283866
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_cAMP_C10H11N5O6P

443656
type: SpeciesReference
stoichiometry: 1.0E-6
species: 286171

289714
type: Reaction
reactant: 405969
reactant: 405993
fast: false
reversible: false
notes: GENE_ASSOCIATION: YLR355C PROTEIN_ASSOCIATION: Ilv5-m SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 1.1.1.86
product: 406005
name: R_ketol_acid_reductoisomerase__2_Aceto_2_hydroxybutanoate___mitochondrial
kinetic law: 406030
reactant: 405981
product: 406018

405969
type: SpeciesReference
stoichiometry: 1.0
species: 282962

282962
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M__S__2_Aceto_2_hydroxybutanoate_C6H9O4

405993
type: SpeciesReference
stoichiometry: 1.0
species: 285439

406005
type: SpeciesReference
stoichiometry: 1.0
species: 282947

299722
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299720
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value: 0.055472

299719
type: LocalParameter
value: 0.0

299717
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299716
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405981
type: SpeciesReference
stoichiometry: 1.0
species: 284796

406018
type: SpeciesReference
stoichiometry: 1.0
species: 285427

290066
type: Reaction
product: 417736
reactant: 417699
reversible: false
kinetic law: 417748
name: R_5__nucleotidase__GMP_
fast: false
reactant: 417711
product: 417723
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.3.5

417736
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species: 285751

417699
type: SpeciesReference
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species: 284690

301108
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301107
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value: 0.0

301105
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value: 0.0

301104
type: LocalParameter
value: 999999.0

301103
type: LocalParameter
value: 0.0

417711
type: SpeciesReference
stoichiometry: 1.0
species: 284757

417723
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stoichiometry: 1.0
species: 284702

284702
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Guanosine_C10H13N5O5

290080
type: Reaction
kinetic law: 418174
product: 418161
reactant: 418149
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Endoplasmic_Reticular PROTEIN_CLASS:
fast: false
reversible: true
name: R_O2__transport__endoplasmic_reticulum

301170
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301167
type: LocalParameter
value: 6.33E-4

301166
type: LocalParameter
value: 0.0

301163
type: LocalParameter
value: 999999.0

301162
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418161
type: SpeciesReference
stoichiometry: 1.0
species: 285496

418149
type: SpeciesReference
stoichiometry: 1.0
species: 285487

288821
type: Reaction
kinetic law: 378457
product: 378445
reactant: 378433
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_octadecenoate__n_C181__exchange

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value: -0.351616

296808
type: LocalParameter
value: 0.0

296807
type: LocalParameter
value: 0.0

296806
type: LocalParameter
value: 999999.0

296804
type: LocalParameter
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378445
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stoichiometry: 1.0
species: 286906

286906
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_octadecenoate__n_C181__C18H33O2

378433
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species: 285541

285541
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_octadecenoate__n_C181__C18H33O2

287113
type: Reaction
name: R_3__4_hydroxyphenyl__lactate_formation
fast: false
kinetic law: 345088
product: 345076
reversible: false
reactant: 345027
product: 345064
reactant: 345052
reactant: 345039
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Quinone_Biosynthesis PROTEIN_CLASS:

291076
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291073
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291072
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291071
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291070
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345076
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species: 285399

345027
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species: 283104

345064
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species: 283098

283098
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_3__4_Hydroxyphenyl_lactate_C9H9O4

345052
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stoichiometry: 1.0
species: 285412

345039
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species: 284796

290320
type: Reaction
fast: false
reactant: 425822
notes: GENE_ASSOCIATION: YNL316C PROTEIN_ASSOCIATION: Pha2 SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.1.51
reversible: false
kinetic law: 425870
name: R_prephenate_dehydratase
product: 425834
reactant: 425810
product: 425846
product: 425858

425822
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stoichiometry: 1.0
species: 285793

285793
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Prephenate_C10H8O6

302172
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value: 0.0

302170
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value: 0.038545

302169
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302167
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value: 999999.0

302166
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425834
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species: 283992

425810
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species: 284787

425846
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species: 284757

425858
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species: 285745

285745
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Phenylpyruvate_C9H7O3

287248
type: Reaction
kinetic law: 347505
product: 347493
reactant: 347481
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_arabinitol_transport_via_passive_diffusion

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291484
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291482
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291480
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291478
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species: 283485

283485
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Arabinitol_C5H12O5

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species: 283488

283488
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: M_L_Arabinitol_C5H12O5

289117
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product: 385753
reactant: 385691
product: 385716
reactant: 385654
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.86
reactant: 385667
product: 385741
product: 385704
kinetic law: 385765
product: 385728
reactant: 385679
name: R_fatty_acyl_CoA_synthase__n_C120CoA_
reversible: false
fast: false

385753
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385691
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species: 285436

385716
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385654
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385667
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species: 284787

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species: 283992

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297695
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297694
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297693
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297691
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385679
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286168
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N_Tetradecanoylglycylpeptide_C18H32N2O4R

290018
type: Reaction
kinetic law: 416212
product: 416200
reactant: 416188
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Nuclear PROTEIN_CLASS:
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reversible: true
name: R_ammonia_nuclear_transport

300907
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300904
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300903
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value: 0.0

300900
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300899
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416200
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species: 285463

285463
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_Ammonium_H4N

416188
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stoichiometry: 1.0
species: 285454

287614
type: Reaction
reactant: 355253
name: R_aldehyde_dehydrogenase__acetylaldehyde__NAD___mitochondrial
kinetic law: 355326
reversible: false
product: 355289
product: 355301
reactant: 355265
reactant: 355277
product: 355314
notes: GENE_ASSOCIATION: YOR374W PROTEIN_ASSOCIATION: Ald4-m SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: 1.2.1.3
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355253
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species: 283518

283518
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Acetaldehyde_C2H4O

292595
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292593
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292591
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292589
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292587
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355289
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species: 283503

283503
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has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Acetate_C2H3O2

355301
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species: 284796

355265
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355277
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355314
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species: 285412

283551
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has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_N_Acetyl_L_glutamate_C7H9NO5

289966
type: Reaction
kinetic law: 414617
product: 414605
reactant: 414593
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
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300680
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300677
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300676
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300673
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300672
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414605
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species: 285424

285424
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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414593
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stoichiometry: 1.0
species: 285421

285523
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

289980
type: Reaction
product: 415090
kinetic law: 415127
reversible: false
fast: false
name: R_nucleoside_diphosphatase__ADP_
reactant: 415065
reactant: 415077
product: 415102
notes: GENE_ASSOCIATION: YER005W PROTEIN_ASSOCIATION: Ynd1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.6.1.6
product: 415115

415090
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species: 283713

300741
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300739
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300738
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300735
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300734
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415065
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species: 283602

415077
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species: 284757

415102
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species: 284787

415115
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species: 285751

286885
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boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Nicotinate_C6H4NO2

286909
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constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_octadecadienoate__n_C182__C18H31O2

290754
type: Reaction
reactant: 440018
kinetic law: 440067
product: 440054
name: R_tyrosine_mitochondrial_transport_via_proton_symport
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
reactant: 440030
reversible: true
fast: false
product: 440042

440018
type: SpeciesReference
stoichiometry: 1.0
species: 284787

303701
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303700
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303698
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303697
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303695
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440054
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stoichiometry: 1.0
species: 286423

286423
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Tyrosine_C9H11NO3

440030
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stoichiometry: 1.0
species: 286417

440042
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stoichiometry: 1.0
species: 284796

288190
type: Reaction
kinetic law: 368107
notes: GENE_ASSOCIATION: YHR144C PROTEIN_ASSOCIATION: Dcd1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 3.5.4.12
reactant: 368071
reactant: 368047
fast: false
reactant: 368059
product: 368083
product: 368095
reversible: true
name: R_dCMP_deaminase

294587
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294584
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value: -6.91E-4

294581
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value: 0.0

294578
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294575
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value: -999999.0

368071
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stoichiometry: 1.0
species: 284757

368047
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stoichiometry: 1.0
species: 284139

368059
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stoichiometry: 1.0
species: 284787

368083
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species: 284301

284301
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_dUMP_C9H11N2O8P

368095
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species: 285454

283305
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_4_Hydroxybenzoate_C7H5O3

289071
type: Reaction
kinetic law: 383091
reactant: 383043
fast: false
reversible: true
product: 383079
name: R_fatty_acid__CoA_ligase__octadecenoate_
reactant: 383030
notes: GENE_ASSOCIATION: ( YOR317W or YIL009W or YMR246W ) PROTEIN_ASSOCIATION: ( Faa1 ) or ( Faa3 ) or ( Faa4 ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 6.2.1.3
product: 383055
product: 383067
reactant: 383018

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297532
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297531
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297529
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383043
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species: 285538

383079
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species: 285796

383030
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species: 284013

383055
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species: 283713

383067
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species: 285577

383018
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stoichiometry: 1.0
species: 283830

290022
type: Reaction
product: 416308
fast: false
name: R_nicotinamide_nucleotide_adenylyltransferase
product: 416296
reactant: 416284
notes: GENE_ASSOCIATION: (YLR328W or YGR010W) PROTEIN_ASSOCIATION: ( Nma1 ) or ( Nma2 ) SUBSYSTEM: S_NAD_Biosynthesis PROTEIN_CLASS: 2.7.7.1
reversible: false
reactant: 416260
reactant: 416272
kinetic law: 416320

416308
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stoichiometry: 1.0
species: 285796

416296
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stoichiometry: 1.0
species: 285396

416284
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species: 285475

416260
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species: 283830

416272
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stoichiometry: 1.0
species: 284787

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300921
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300918
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300917
type: LocalParameter
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285146
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Leucine_C6H13NO2

283977
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

286084
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Spermine_C10H30N4

283233
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3_Phospho_D_glycerate_C3H4O7P

287023
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boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Uracil_C4H4N2O2

284163
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Dodecanoate__n_C120__C12H23O2

288241
type: Reaction
kinetic law: 369266
product: 369253
reactant: 369241
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
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294808
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294805
type: LocalParameter
value: 3.700069

294802
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value: 0.0

294799
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value: 999999.0

294796
type: LocalParameter
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369253
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stoichiometry: 1.0
species: 284196

284196
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Dihydroxyacetone_phosphate_C3H5O6P

369241
type: SpeciesReference
stoichiometry: 1.0
species: 284199

288860
type: Reaction
kinetic law: 378928
product: 378916
reactant: 378904
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_phosphatidyl_1D_myo_inositol__yeast_specific_exchange

296914
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value: -57.421487

296912
type: LocalParameter
value: 0.0

296911
type: LocalParameter
value: 0.0

296910
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value: 999999.0

296908
type: LocalParameter
value: 0.0

378916
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stoichiometry: 1.0
species: 286945

286945
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870

378904
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stoichiometry: 1.0
species: 285901

285901
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870

286153
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

283254
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_4_Aminobutanoate_C4H9NO2

283920
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_2__Phytosphingosinen_C260__C44H89NO4

289125
type: Reaction
reactant: 386179
product: 386251
product: 386203
fast: false
product: 386227
kinetic law: 386263
reactant: 386191
reactant: 386155
reactant: 386167
reversible: false
name: R_fatty_acid_synthase__n_C141_
notes: GENE_ASSOCIATION: YJL196C PROTEIN_ASSOCIATION: Elo1 SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.85
product: 386239
product: 386215
reactant: 386142

386179
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stoichiometry: 3.0
species: 285436

386251
type: SpeciesReference
stoichiometry: 1.0
species: 286411

386203
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species: 283992

386227
type: SpeciesReference
stoichiometry: 3.0
species: 284757

297722
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297721
type: LocalParameter
value: 0.0

297719
type: LocalParameter
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297718
type: LocalParameter
value: 999999.0

297717
type: LocalParameter
value: 0.0

386191
type: SpeciesReference
stoichiometry: 1.0
species: 285487

386155
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stoichiometry: 4.0
species: 284787

386167
type: SpeciesReference
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species: 285219

386239
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species: 285421

386215
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stoichiometry: 1.0
species: 284013

386142
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stoichiometry: 1.0
species: 284160

284160
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Dodecanoate__n_C120__C12H23O2

289744
type: Reaction
notes: GENE_ASSOCIATION: ( YBR069C or YKR039W or YCL025C or YBR068C or YDR046C or YDR508C ) PROTEIN_ASSOCIATION: ( Tat1 ) or ( Gap1 ) or ( Agp1 ) or ( Bap2 ) or ( Bap3 ) or ( Gnp1 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
name: R_L_leucine_reversible_transport_via_proton_symport
reactant: 407201
product: 407225
kinetic law: 407249
reversible: true
fast: false
reactant: 407213
product: 407237

407201
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stoichiometry: 1.0
species: 284790

407225
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stoichiometry: 1.0
species: 284787

299826
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299824
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value: 0.0

299823
type: LocalParameter
value: 0.0

299821
type: LocalParameter
value: 999999.0

299820
type: LocalParameter
value: -999999.0

407213
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stoichiometry: 1.0
species: 285143

285143
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Leucine_C6H13NO2

407237
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stoichiometry: 1.0
species: 285140

284978
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_isobutyl_alcohol_C4H10O

288851
type: Reaction
kinetic law: 378819
product: 378807
reactant: 378795
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Phosphate_exchange

296890
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value: 0.0

296888
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value: -0.056911

296887
type: LocalParameter
value: 0.0

296886
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value: 999999.0

296884
type: LocalParameter
value: -999999.0

378807
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stoichiometry: 1.0
species: 286936

286936
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Phosphate_HO4P

378795
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stoichiometry: 1.0
species: 285754

285754
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Phosphate_HO4P

288010
type: Reaction
fast: false
reversible: true
name: R_citrate_transport__mitochondrial
reactant: 364270
notes: GENE_ASSOCIATION: YBR291C PROTEIN_ASSOCIATION: Ctp1-m SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
product: 364294
reactant: 364282
product: 364306
kinetic law: 364318

364270
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species: 283962

364294
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species: 285207

364282
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species: 285213

364306
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species: 283968

293833
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293831
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293829
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293827
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293824
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289329
type: Reaction
fast: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Quinone_Biosynthesis PROTEIN_CLASS:
product: 393935
reactant: 393911
name: R_geranylgeranyltranstransferase
reversible: false
product: 393923
reactant: 393899
kinetic law: 393947

393935
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stoichiometry: 1.0
species: 285796

393911
type: SpeciesReference
stoichiometry: 1.0
species: 285083

393923
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stoichiometry: 1.0
species: 285694

285694
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_all_trans_Pentaprenyl_diphosphate_C25H41O7P2

393899
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stoichiometry: 1.0
species: 284580

284580
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Geranylgeranyl_diphosphate_C20H33O7P2

298396
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298394
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value: 0.0

298393
type: LocalParameter
value: 0.0

298391
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298390
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288397
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kinetic law: 372461
product: 372449
product: 372437
reactant: 372425
notes: GENE_ASSOCIATION: YKR009C PROTEIN_ASSOCIATION: Fox2-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 4.2.1.17
fast: false
reversible: true
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295484
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295481
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value: 0.0

295478
type: LocalParameter
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295475
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295472
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372449
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stoichiometry: 1.0
species: 284778

372437
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stoichiometry: 1.0
species: 284109

372425
type: SpeciesReference
stoichiometry: 1.0
species: 283158

283158
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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283050
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_methylbutyraldehyde_C5H10O

285330
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

289884
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reversible: false
notes: GENE_ASSOCIATION: YER019W PROTEIN_ASSOCIATION: Isc1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
kinetic law: 411921
product: 411897
reactant: 411861
name: R_Mannose__inositol_P_2_ceramide__ceramide_3__24C__phospholipase_C
product: 411885
product: 411909
fast: false
reactant: 411873

300346
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300345
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300343
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300342
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300339
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411897
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species: 284787

411861
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stoichiometry: 1.0
species: 284757

411885
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species: 283932

283932
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_3__Phytosphingosinen_C240OH__C42H85NO5

411909
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species: 285234

285234
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initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Mannose__inositol_P_2_C18H31O22P2

411873
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species: 285333

285333
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

289996
type: Reaction
reactant: 415611
fast: false
name: R_nucleoside_diphosphate_kinase__ATPdTDP_
product: 415647
kinetic law: 415659
product: 415635
notes: GENE_ASSOCIATION: YKL067W PROTEIN_ASSOCIATION: Ynk1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6
reversible: true
reactant: 415623

415611
type: SpeciesReference
stoichiometry: 1.0
species: 283830

415647
type: SpeciesReference
stoichiometry: 1.0
species: 284289

284289
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_dTTP_C10H13N2O14P3

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value: 0.0

300806
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value: 0.0

300805
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value: 0.0

300802
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value: 999999.0

300801
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value: -999999.0

415635
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stoichiometry: 1.0
species: 283602

415623
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stoichiometry: 1.0
species: 284283

284283
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_dTDP_C10H13N2O11P2

288388
type: Reaction
kinetic law: 372328
product: 372316
reactant: 372304
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_erythro_4_hydroxyglutamate_peroxisomal_transport_via_diffusion

295445
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value: 0.0

295442
type: LocalParameter
value: 0.0

295439
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value: 0.0

295436
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value: 999999.0

295433
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value: -999999.0

372316
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stoichiometry: 1.0
species: 284322

284322
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_L_erythro_4_Hydroxyglutamate_C5H8NO5

372304
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stoichiometry: 1.0
species: 284316

284316
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_erythro_4_Hydroxyglutamate_C5H8NO5

287206
type: Reaction
kinetic law: 346633
name: R_L_4_hydroxyglutamate_semialdehyde_dehydrogenase__mitochondrial
fast: false
product: 346597
product: 346621
reactant: 346573
reactant: 346561
product: 346609
reversible: true
reactant: 346585
notes: GENE_ASSOCIATION: YHR037W PROTEIN_ASSOCIATION: Put2-m SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.12

291360
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291358
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value: 0.0

291356
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value: 0.0

291354
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value: 999999.0

291352
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value: -999999.0

346597
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stoichiometry: 1.0
species: 284319

284319
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_erythro_4_Hydroxyglutamate_C5H8NO5

346621
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stoichiometry: 1.0
species: 285412

346573
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stoichiometry: 1.0
species: 284766

346561
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stoichiometry: 1.0
species: 283311

283311
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_4_Hydroxyglutamate_semialdehyde_C5H9NO4

346609
type: SpeciesReference
stoichiometry: 2.0
species: 284796

346585
type: SpeciesReference
stoichiometry: 1.0
species: 285399

288755
type: Reaction
kinetic law: 377653
product: 377641
reactant: 377629
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Inosine_exchange

296634
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value: -0.137795

296632
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value: 0.0

296631
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value: 0.0

296630
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value: 999999.0

296628
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value: 0.0

377641
type: SpeciesReference
stoichiometry: 1.0
species: 286840

377629
type: SpeciesReference
stoichiometry: 1.0
species: 285062

285062
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Inosine_C10H12N4O5

290784
type: Reaction
kinetic law: 440950
product: 440938
product: 440926
reactant: 440914
notes: GENE_ASSOCIATION: YOR278W PROTEIN_ASSOCIATION: Hem4 SUBSYSTEM: S_Porphyrin_and_Chlorophyll_Metabolism PROTEIN_CLASS: 4.2.1.75
fast: false
reversible: false
name: R_uroporphyrinogen_III_synthase

303806
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value: 0.0

303805
type: LocalParameter
value: 0.0

303803
type: LocalParameter
value: 0.0

303802
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value: 999999.0

303800
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value: 0.0

440938
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stoichiometry: 1.0
species: 286465

286465
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Uroporphyrinogen_III_C40H36N4O16

440926
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stoichiometry: 1.0
species: 284757

440914
type: SpeciesReference
stoichiometry: 1.0
species: 284921

290164
type: Reaction
product: 420568
reactant: 420544
product: 420580
reactant: 420556
notes: GENE_ASSOCIATION: YOR360C PROTEIN_ASSOCIATION: Pde2 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 3.1.4.17
fast: false
name: R_3__5__cyclic_nucleotide_phosphodiesterase
kinetic law: 420592
reversible: false

420568
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stoichiometry: 1.0
species: 284787

420544
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stoichiometry: 1.0
species: 283119

283119
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3__5__Cyclic_IMP_C10H10N4O7P

420580
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stoichiometry: 1.0
species: 285029

420556
type: SpeciesReference
stoichiometry: 1.0
species: 284757

301543
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301542
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value: 0.0

301539
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value: 0.0

301538
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value: 999999.0

301535
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value: 0.0

286843
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_potassium_K

290712
type: Reaction
fast: false
product: 438661
product: 438637
notes: GENE_ASSOCIATION: ( ( YBR126C and YDR074W and YML100W ) or ( YBR126C and YDR074W and YMR261C ) ) PROTEIN_ASSOCIATION: ( TpsI ) or ( Tps3 ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.15
reversible: false
kinetic law: 438673
name: R_alpha_alpha_trehalose_phosphate_synthase__UDP_forming_
reactant: 438613
product: 438649
reactant: 438625

438661
type: SpeciesReference
stoichiometry: 1.0
species: 286438

438637
type: SpeciesReference
stoichiometry: 1.0
species: 284787

303554
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value: 0.0

303553
type: LocalParameter
value: 0.006736

303551
type: LocalParameter
value: 0.0

303550
type: LocalParameter
value: 999999.0

303548
type: LocalParameter
value: 0.0

438613
type: SpeciesReference
stoichiometry: 1.0
species: 284523

438649
type: SpeciesReference
stoichiometry: 1.0
species: 286255

286255
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_alpha_alpha__Trehalose_6_phosphate_C12H21O14P

438625
type: SpeciesReference
stoichiometry: 1.0
species: 286447

289165
type: Reaction
kinetic law: 388534
product: 388522
product: 388510
reactant: 388497
notes: GENE_ASSOCIATION: YKL060C PROTEIN_ASSOCIATION: Fba1 SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 4.1.2.13
fast: false
reversible: true
name: R_Sedoheptulose_1_7_bisphosphate_D_glyceraldehyde_3_phosphate_lyase

297861
type: LocalParameter
value: 0.0

297859
type: LocalParameter
value: 0.0

297858
type: LocalParameter
value: 0.0

297857
type: LocalParameter
value: 999999.0

297855
type: LocalParameter
value: -999999.0

388522
type: SpeciesReference
stoichiometry: 1.0
species: 284325

284325
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Erythrose_4_phosphate_C4H7O7P

388510
type: SpeciesReference
stoichiometry: 1.0
species: 284196

388497
type: SpeciesReference
stoichiometry: 1.0
species: 286000

286000
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Sedoheptulose_1_7_bisphosphate_C7H12O13P2

289784
type: Reaction
product: 408662
reactant: 408614
fast: false
reactant: 408602
name: R_malate_synthase
product: 408650
product: 408638
kinetic law: 408674
notes: GENE_ASSOCIATION: ( YIR031C or YNL117W ) PROTEIN_ASSOCIATION: ( Dal7 ) or ( Mls1 ) SUBSYSTEM: S_Anaplerotic_Reactions PROTEIN_CLASS: 4.1.3.2
reversible: false
reactant: 408626

408662
type: SpeciesReference
stoichiometry: 1.0
species: 285207

408614
type: SpeciesReference
stoichiometry: 1.0
species: 284648

284648
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Glyoxylate_C2H1O3

408602
type: SpeciesReference
stoichiometry: 1.0
species: 283521

408650
type: SpeciesReference
stoichiometry: 1.0
species: 284787

408638
type: SpeciesReference
stoichiometry: 1.0
species: 284013

299971
type: LocalParameter
value: -0.023758

299970
type: LocalParameter
value: 0.0

299969
type: LocalParameter
value: 0.0

299966
type: LocalParameter
value: 999999.0

299965
type: LocalParameter
value: 0.0

408626
type: SpeciesReference
stoichiometry: 1.0
species: 284757

285769
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_Phosphate_HO4P

289800
type: Reaction
kinetic law: 409133
product: 409121
reactant: 409109
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Endoplasmic_Reticular PROTEIN_CLASS:
fast: false
reversible: true
name: R_mannan_endoplasmic_reticulum_transport_via_diffusion

300027
type: LocalParameter
value: 0.0

300025
type: LocalParameter
value: -0.232567

300024
type: LocalParameter
value: 0.0

300021
type: LocalParameter
value: 999999.0

300020
type: LocalParameter
value: -999999.0

409121
type: SpeciesReference
stoichiometry: 1.0
species: 285252

409109
type: SpeciesReference
stoichiometry: 1.0
species: 285249

290116
type: Reaction
fast: false
name: R_Ornithine_Decarboxylase
product: 419167
reactant: 419130
product: 419154
reversible: false
kinetic law: 419179
notes: GENE_ASSOCIATION: YKL184W PROTEIN_ASSOCIATION: Spe1 SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 4.1.1.17
reactant: 419142

419167
type: SpeciesReference
stoichiometry: 1.0
species: 285922

285922
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Putrescine_C4H14N2

419130
type: SpeciesReference
stoichiometry: 1.0
species: 284787

419154
type: SpeciesReference
stoichiometry: 1.0
species: 283992

301327
type: LocalParameter
value: 0.0

301326
type: LocalParameter
value: 0.0

301323
type: LocalParameter
value: 0.0

301322
type: LocalParameter
value: 999999.0

301319
type: LocalParameter
value: 0.0

419142
type: SpeciesReference
stoichiometry: 1.0
species: 285592

285592
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ornithine_C5H13N2O2

289912
type: Reaction
name: R_mannose_inositiol_phophorylceramide_synthase__ceramide_1__24C___yeast_specific
kinetic law: 412865
product: 412853
reactant: 412816
reversible: false
fast: false
product: 412841
notes: GENE_ASSOCIATION: ( ( YBR036C and YPL057C ) or ( YBR036C and YBR161W ) ) PROTEIN_ASSOCIATION: ( Mipcs1 ) or ( Mipcs2 ) SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
reactant: 412804
product: 412828

300461
type: LocalParameter
value: -0.10691

300460
type: LocalParameter
value: 0.0

300457
type: LocalParameter
value: 0.0

300456
type: LocalParameter
value: 999999.0

300453
type: LocalParameter
value: 0.0

412853
type: SpeciesReference
stoichiometry: 0.01
species: 285339

285339
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

412816
type: SpeciesReference
stoichiometry: 0.01
species: 285065

412841
type: SpeciesReference
stoichiometry: 1.0
species: 284787

412804
type: SpeciesReference
stoichiometry: 1.0
species: 284574

284574
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_GDP_D_mannose_C16H23N5O16P2

412828
type: SpeciesReference
stoichiometry: 1.0
species: 284562

289237
type: Reaction
reactant: 390905
reactant: 390893
product: 390929
product: 390917
reversible: true
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
kinetic law: 390941
name: R_fumarate_reversible_transport_via_symport

390905
type: SpeciesReference
stoichiometry: 1.0
species: 284790

390893
type: SpeciesReference
stoichiometry: 1.0
species: 284496

284496
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Fumarate_C4H2O4

390929
type: SpeciesReference
stoichiometry: 1.0
species: 284787

390917
type: SpeciesReference
stoichiometry: 1.0
species: 284493

298097
type: LocalParameter
value: 0.0

298095
type: LocalParameter
value: 0.0

298094
type: LocalParameter
value: 0.0

298092
type: LocalParameter
value: 999999.0

298091
type: LocalParameter
value: -999999.0

282981
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_1__2_Carboxyphenylamino__1_deoxy_D_ribulose_5_phosphate_C12H13NO9P

283878
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Carbamoyl_phosphate_CH2NO5P

287367
type: Reaction
kinetic law: 349810
product: 349798
reactant: 349786
notes: GENE_ASSOCIATION: ( YLR304C or YJL200C ) PROTEIN_ASSOCIATION: ( Aco1-m ) or ( Aco2-m ) SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: 4.2.1.3
fast: false
reversible: true
name: R_Aconitate_hydratase

291835
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value: 0.0

291833
type: LocalParameter
value: 0.263224

291831
type: LocalParameter
value: 0.0

291829
type: LocalParameter
value: 999999.0

291827
type: LocalParameter
value: -999999.0

349798
type: SpeciesReference
stoichiometry: 1.0
species: 284987

284987
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Isocitrate_C6H5O7

349786
type: SpeciesReference
stoichiometry: 1.0
species: 283968

290120
type: Reaction
reactant: 419252
reactant: 419264
kinetic law: 419300
fast: false
product: 419276
name: R_ornithine_transacetylase__irreversible__mitochondrial
product: 419288
reversible: false
notes: GENE_ASSOCIATION: YMR062C PROTEIN_ASSOCIATION: Ecm40-m SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.3.1.35

419252
type: SpeciesReference
stoichiometry: 1.0
species: 283563

283563
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_N2_Acetyl_L_ornithine_C7H14N2O3

419264
type: SpeciesReference
stoichiometry: 1.0
species: 284624

301345
type: LocalParameter
value: 0.0

301344
type: LocalParameter
value: 0.04626

301341
type: LocalParameter
value: 0.0

301340
type: LocalParameter
value: 999999.0

301337
type: LocalParameter
value: 0.0

419276
type: SpeciesReference
stoichiometry: 1.0
species: 283551

419288
type: SpeciesReference
stoichiometry: 1.0
species: 285598

285598
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Ornithine_C5H13N2O2

285288
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_Methyltetrahydropteroyltri_L_glutamate_C25H36N8O12

283167
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

289838
type: Reaction
reactant: 410375
name: R_methionyl_tRNA_synthetase__mitochondrial
kinetic law: 410423
reversible: false
product: 410411
reactant: 410351
fast: false
reactant: 410363
notes: GENE_ASSOCIATION: YGR171C PROTEIN_ASSOCIATION: Msm1-m SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.10
product: 410399
product: 410387

410375
type: SpeciesReference
stoichiometry: 1.0
species: 286333

286333
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_tRNA_Met__R

300180
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value: -0.107504

300179
type: LocalParameter
value: 0.0

300177
type: LocalParameter
value: 0.0

300176
type: LocalParameter
value: 999999.0

300174
type: LocalParameter
value: 0.0

410411
type: SpeciesReference
stoichiometry: 1.0
species: 285799

410351
type: SpeciesReference
stoichiometry: 1.0
species: 283836

410363
type: SpeciesReference
stoichiometry: 1.0
species: 285270

285270
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Methionine_C5H11NO2S

410399
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stoichiometry: 1.0
species: 285282

285282
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Methionyl_tRNA__Met__C5H10NOSR

410387
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stoichiometry: 1.0
species: 283716

288794
type: Reaction
kinetic law: 378127
product: 378115
reactant: 378103
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_S_Methyl_L_methionine_exchange

296738
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value: 0.0

296736
type: LocalParameter
value: 0.0

296735
type: LocalParameter
value: 0.0

296734
type: LocalParameter
value: 999999.0

296732
type: LocalParameter
value: 0.0

378115
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stoichiometry: 1.0
species: 286879

286879
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_S_Methyl_L_methionine_C6H14NO2S

378103
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stoichiometry: 1.0
species: 285366

285366
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_S_Methyl_L_methionine_C6H14NO2S

287986
type: Reaction
notes: GENE_ASSOCIATION: YGL077C PROTEIN_ASSOCIATION: Hnm1 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
kinetic law: 363857
product: 363845
product: 363833
name: R_choline_transport_via_proton_symport
reactant: 363809
reactant: 363821
fast: false
reversible: false

293753
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293751
type: LocalParameter
value: 0.0

293749
type: LocalParameter
value: 0.0

293747
type: LocalParameter
value: 999999.0

293744
type: LocalParameter
value: 0.0

363845
type: SpeciesReference
stoichiometry: 1.0
species: 284787

363833
type: SpeciesReference
stoichiometry: 1.0
species: 283950

283950
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Choline_C5H14NO

363809
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stoichiometry: 1.0
species: 283953

363821
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species: 284790

286708
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initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_episterol_C28H46O

283173
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

288962
type: Reaction
kinetic law: 380160
product: 380148
reactant: 380136
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_zymosterol_exchange

297185
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value: -0.664229

297183
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value: 0.0

297182
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value: 0.0

297181
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value: 999999.0

297179
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value: 0.0

380148
type: SpeciesReference
stoichiometry: 1.0
species: 287047

287047
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_zymosterol_C27H44O

380136
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species: 286552

286552
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_zymosterol_C27H44O

287418
type: Reaction
reactant: 350775
name: R_adenine_transport_in_via_proton_symport
fast: false
reversible: false
product: 350812
product: 350799
notes: GENE_ASSOCIATION: ( YER056C or YER060W or YER060W-A or YGL186C ) PROTEIN_ASSOCIATION: ( Fcy2 ) or ( Fcy21 ) or ( Fcy22 ) or ( Fcy23 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
kinetic law: 350824
reactant: 350787

350775
type: SpeciesReference
stoichiometry: 1.0
species: 283587

350812
type: SpeciesReference
stoichiometry: 1.0
species: 284787

350799
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stoichiometry: 1.0
species: 283584

291990
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value: 0.0

291988
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value: 0.0

291986
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value: 0.0

291984
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value: 999999.0

291981
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value: 0.0

350787
type: SpeciesReference
stoichiometry: 1.0
species: 284790

286960
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Sorbitol_C6H14O6

290060
type: Reaction
kinetic law: 417565
product: 417540
reactant: 417528
reversible: false
fast: false
product: 417553
reactant: 417515
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.3.5
name: R_5__nucleotidase__dAMP_

301085
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301084
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value: 0.0

301082
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value: 0.0

301081
type: LocalParameter
value: 999999.0

301080
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value: 0.0

417540
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stoichiometry: 1.0
species: 284079

417528
type: SpeciesReference
stoichiometry: 1.0
species: 284757

417553
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stoichiometry: 1.0
species: 285751

417515
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stoichiometry: 1.0
species: 284094

284226
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Dihydropteroate_C14H13N6O3

285005
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_IDP_C10H11N4O11P2

288524
type: Reaction
kinetic law: 374850
product: 374838
reactant: 374826
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Acetate_exchange

296012
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value: -1.98E-4

296010
type: LocalParameter
value: 0.0

296009
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value: 0.0

296008
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value: 999999.0

296006
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374838
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stoichiometry: 1.0
species: 286609

286609
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Acetate_C2H3O2

374826
type: SpeciesReference
stoichiometry: 1.0
species: 283500

289792
type: Reaction
product: 408916
name: R_L_malate_reversible_transport_via_proton_symport
reactant: 408892
reactant: 408880
product: 408904
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
reversible: true
fast: false
kinetic law: 408928

408916
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stoichiometry: 1.0
species: 285207

408892
type: SpeciesReference
stoichiometry: 1.0
species: 285210

408880
type: SpeciesReference
stoichiometry: 1.0
species: 284790

408904
type: SpeciesReference
stoichiometry: 1.0
species: 284787

299996
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value: 0.0

299994
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value: 0.0

299993
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value: 0.0

299992
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value: 999999.0

299991
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value: -999999.0

287593
type: Reaction
kinetic law: 354737
reactant: 354700
reversible: false
name: R_alcohol_dehydrogenase__reverse_rxn__acetaldehyde___ethanol___mitochondrial
product: 354713
product: 354725
notes: GENE_ASSOCIATION: YMR083W PROTEIN_ASSOCIATION: Adh3-m SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: 1.1.1.1
reactant: 354675
fast: false
reactant: 354688

292531
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292529
type: LocalParameter
value: 1.011777

292527
type: LocalParameter
value: 0.0

292525
type: LocalParameter
value: 999999.0

292523
type: LocalParameter
value: 0.0

354700
type: SpeciesReference
stoichiometry: 1.0
species: 285412

354713
type: SpeciesReference
stoichiometry: 1.0
species: 284394

284394
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Ethanol_C2H6O

354725
type: SpeciesReference
stoichiometry: 1.0
species: 285399

354675
type: SpeciesReference
stoichiometry: 1.0
species: 283518

354688
type: SpeciesReference
stoichiometry: 1.0
species: 284796

289842
type: Reaction
reversible: true
kinetic law: 410543
reactant: 410507
fast: false
product: 410519
name: R_L_methionine_reversible_transport_via_proton_symport
reactant: 410495
notes: GENE_ASSOCIATION: ( YKR039W or YCL025C or YDR508C or YBR068C or YDR046C or YGR055W or YHL036W ) PROTEIN_ASSOCIATION: ( Gap1 ) or ( Agp1 ) or ( Gnp1 ) or ( Bap2 ) or ( Bap3 ) or ( Mup1 ) or ( Mup3 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
product: 410531

300194
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300193
type: LocalParameter
value: 0.0

300191
type: LocalParameter
value: 0.0

300190
type: LocalParameter
value: 999999.0

300188
type: LocalParameter
value: -999999.0

410507
type: SpeciesReference
stoichiometry: 1.0
species: 285267

285267
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Methionine_C5H11NO2S

410519
type: SpeciesReference
stoichiometry: 1.0
species: 284787

410495
type: SpeciesReference
stoichiometry: 1.0
species: 284790

410531
type: SpeciesReference
stoichiometry: 1.0
species: 285264

286312
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_tRNA_Ile__R

290194
type: Reaction
kinetic law: 421500
name: R_6_phosphofructo_2_kinase
product: 421464
product: 421488
product: 421476
reversible: false
reactant: 421452
reactant: 421440
notes: GENE_ASSOCIATION: ( YIL107C or YOL136C ) PROTEIN_ASSOCIATION: ( Pfk26 ) or ( Pfk27 ) SUBSYSTEM: S_Fructose_and_Mannose_Metabolism PROTEIN_CLASS: 2.7.1.105
fast: false

301678
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value: -0.011879

301677
type: LocalParameter
value: 0.0

301674
type: LocalParameter
value: 0.0

301673
type: LocalParameter
value: 999999.0

301670
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value: 0.0

421464
type: SpeciesReference
stoichiometry: 1.0
species: 283602

421488
type: SpeciesReference
stoichiometry: 1.0
species: 284787

421476
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stoichiometry: 1.0
species: 284400

421452
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stoichiometry: 1.0
species: 284403

421440
type: SpeciesReference
stoichiometry: 1.0
species: 283830

285243
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Mannose_C6H12O6

290728
type: Reaction
fast: false
reversible: true
reactant: 439169
product: 439193
notes: GENE_ASSOCIATION: ( YGL202W or YHR137W ) PROTEIN_ASSOCIATION: ( Aro8 ) or ( Aro9 ) SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS:
product: 439205
name: R_tryptophan_transaminase
kinetic law: 439217
reactant: 439181

439169
type: SpeciesReference
stoichiometry: 1.0
species: 283641

439193
type: SpeciesReference
stoichiometry: 1.0
species: 284618

439205
type: SpeciesReference
stoichiometry: 1.0
species: 285050

285050
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Indolepyruvate_C11H8NO3

303610
type: LocalParameter
value: 0.0

303609
type: LocalParameter
value: 0.0

303607
type: LocalParameter
value: 0.0

303606
type: LocalParameter
value: 999999.0

303604
type: LocalParameter
value: -999999.0

439181
type: SpeciesReference
stoichiometry: 1.0
species: 286372

290742
type: Reaction
reactant: 439603
fast: false
notes: GENE_ASSOCIATION: YDR403W PROTEIN_ASSOCIATION: Dit1 SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.1.2.3
name: R_L_tyrosine_N_formyltransferase
reactant: 439591
kinetic law: 439652
product: 439628
reversible: false
product: 439640
product: 439616

439603
type: SpeciesReference
stoichiometry: 1.0
species: 286417

439591
type: SpeciesReference
stoichiometry: 1.0
species: 282889

282889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_10_Formyltetrahydrofolate_C20H21N7O7

303659
type: LocalParameter
value: -0.073253

303658
type: LocalParameter
value: 0.0

303656
type: LocalParameter
value: 0.0

303655
type: LocalParameter
value: 999999.0

303653
type: LocalParameter
value: 0.0

439628
type: SpeciesReference
stoichiometry: 1.0
species: 284787

439640
type: SpeciesReference
stoichiometry: 1.0
species: 286171

439616
type: SpeciesReference
stoichiometry: 1.0
species: 283458

283458
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N_Formyl_L_tyrosine_C10H10NO4

290146
type: Reaction
kinetic law: 420061
product: 420049
reactant: 420037
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_pantothenate_mitochondrial_transport

301462
type: LocalParameter
value: 0.0

301461
type: LocalParameter
value: 0.0

301458
type: LocalParameter
value: 0.0

301457
type: LocalParameter
value: 999999.0

301454
type: LocalParameter
value: -999999.0

420049
type: SpeciesReference
stoichiometry: 1.0
species: 285652

420037
type: SpeciesReference
stoichiometry: 1.0
species: 285649

285649
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M__R__Pantoate_C6H11O4

286006
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Sulfur_S

289379
type: Reaction
product: 395543
fast: false
name: R_glutaminase
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Glutamine_Metabolism PROTEIN_CLASS: 3.5.1.2
reactant: 395519
reactant: 395531
kinetic law: 395567
product: 395555
reversible: false

395543
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stoichiometry: 1.0
species: 284618

395519
type: SpeciesReference
stoichiometry: 1.0
species: 284595

395531
type: SpeciesReference
stoichiometry: 1.0
species: 284757

298565
type: LocalParameter
value: -0.011879

298563
type: LocalParameter
value: 0.0

298562
type: LocalParameter
value: 0.0

298560
type: LocalParameter
value: 999999.0

298559
type: LocalParameter
value: 0.0

395555
type: SpeciesReference
stoichiometry: 1.0
species: 285454

284823
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_Bicarbonate_CHO3

289123
type: Reaction
reactant: 386045
reactant: 386058
reactant: 386032
reversible: false
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.86
product: 386082
fast: false
product: 386094
product: 386106
product: 386118
name: R_fatty_acyl_CoA_synthase__n_C140CoA_
reactant: 386020
product: 386070
kinetic law: 386130

386045
type: SpeciesReference
stoichiometry: 1.0
species: 285219

386058
type: SpeciesReference
stoichiometry: 2.0
species: 285436

386032
type: SpeciesReference
stoichiometry: 3.0
species: 284787

386082
type: SpeciesReference
stoichiometry: 1.0
species: 284013

386094
type: SpeciesReference
stoichiometry: 1.0
species: 284757

386106
type: SpeciesReference
stoichiometry: 2.0
species: 285421

386118
type: SpeciesReference
stoichiometry: 1.0
species: 286150

386020
type: SpeciesReference
stoichiometry: 1.0
species: 284169

386070
type: SpeciesReference
stoichiometry: 1.0
species: 283992

297716
type: LocalParameter
value: 0.0

297714
type: LocalParameter
value: 0.014831

297713
type: LocalParameter
value: 0.0

297712
type: LocalParameter
value: 999999.0

297710
type: LocalParameter
value: 0.0

287764
type: Reaction
reactant: 358535
fast: false
reversible: true
name: R_aspartate_transaminase
notes: GENE_ASSOCIATION: YLR027C PROTEIN_ASSOCIATION: Aat2 SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism PROTEIN_CLASS: 2.6.1.1
product: 358559
kinetic law: 358571
reactant: 358523
product: 358547

358535
type: SpeciesReference
stoichiometry: 1.0
species: 283800

358559
type: SpeciesReference
stoichiometry: 1.0
species: 285502

285502
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Oxaloacetate_C4H2O5

293046
type: LocalParameter
value: 0.0

293044
type: LocalParameter
value: -0.386134

293042
type: LocalParameter
value: 0.0

293040
type: LocalParameter
value: 999999.0

293038
type: LocalParameter
value: -999999.0

358523
type: SpeciesReference
stoichiometry: 1.0
species: 283641

358547
type: SpeciesReference
stoichiometry: 1.0
species: 284618

289544
type: Reaction
kinetic law: 400712
product: 400700
reactant: 400688
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: true
name: R_fatty_acid_intracellular_transport

299124
type: LocalParameter
value: 0.0

299122
type: LocalParameter
value: 0.0

299121
type: LocalParameter
value: 0.0

299119
type: LocalParameter
value: 999999.0

299118
type: LocalParameter
value: -999999.0

400700
type: SpeciesReference
stoichiometry: 1.0
species: 284882

284882
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

400688
type: SpeciesReference
stoichiometry: 1.0
species: 284876

287899
type: Reaction
fast: false
product: 361818
notes: GENE_ASSOCIATION: ( ( YJR109C and YOR303W ) or YJL130C ) PROTEIN_ASSOCIATION: ( Cpa ) or ( Ura2 ) SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 6.3.5.5
reactant: 361720
reactant: 361757
reactant: 361732
kinetic law: 361830
reactant: 361744
product: 361781
name: R_carbamoyl_phosphate_synthase__glutamine_hydrolysing_
reversible: false
product: 361806
product: 361769
product: 361793

361818
type: SpeciesReference
stoichiometry: 1.0
species: 285751

361720
type: SpeciesReference
stoichiometry: 2.0
species: 283830

361757
type: SpeciesReference
stoichiometry: 1.0
species: 284817

284817
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Bicarbonate_CHO3

361732
type: SpeciesReference
stoichiometry: 1.0
species: 284595

293457
type: LocalParameter
value: 0.0

293455
type: LocalParameter
value: 0.078098

293453
type: LocalParameter
value: 0.0

293451
type: LocalParameter
value: 999999.0

293448
type: LocalParameter
value: 0.0

361744
type: SpeciesReference
stoichiometry: 1.0
species: 284757

361781
type: SpeciesReference
stoichiometry: 1.0
species: 283878

361806
type: SpeciesReference
stoichiometry: 2.0
species: 284787

361769
type: SpeciesReference
stoichiometry: 2.0
species: 283602

361793
type: SpeciesReference
stoichiometry: 1.0
species: 284618

285101
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_potassium_K

286825
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constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_isobutyl_alcohol_C4H10O

289734
type: Reaction
kinetic law: 406897
fast: false
product: 406885
product: 406873
reactant: 406861
name: R_L_cystine_transport_via_proton_symport__vacuolar_
reactant: 406849
reversible: false
notes: GENE_ASSOCIATION: YCR075C PROTEIN_ASSOCIATION: Ers1-v SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:

299791
type: LocalParameter
value: 0.0

299789
type: LocalParameter
value: 0.0

299788
type: LocalParameter
value: 0.0

299786
type: LocalParameter
value: 999999.0

299785
type: LocalParameter
value: 0.0

406885
type: SpeciesReference
stoichiometry: 1.0
species: 284787

406873
type: SpeciesReference
stoichiometry: 1.0
species: 283431

406861
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stoichiometry: 1.0
species: 284805

406849
type: SpeciesReference
stoichiometry: 1.0
species: 283434

283434
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_L_Cystine_C6H12N2O4S2

290318
type: Reaction
reversible: false
fast: false
reactant: 425749
reactant: 425737
product: 425774
product: 425761
notes: GENE_ASSOCIATION: YBR166C PROTEIN_ASSOCIATION: Tyr1 SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 1.3.1.13
product: 425786
kinetic law: 425798
name: R_prephenate_dehydrogenase__NADP_

425749
type: SpeciesReference
stoichiometry: 1.0
species: 285793

425737
type: SpeciesReference
stoichiometry: 1.0
species: 285421

425774
type: SpeciesReference
stoichiometry: 1.0
species: 283992

425761
type: SpeciesReference
stoichiometry: 1.0
species: 283101

425786
type: SpeciesReference
stoichiometry: 1.0
species: 285436

302165
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value: 0.0

302163
type: LocalParameter
value: 0.029362

302162
type: LocalParameter
value: 0.0

302160
type: LocalParameter
value: 999999.0

302159
type: LocalParameter
value: 0.0

287326
type: Reaction
name: R_acetolactate_synthase__mitochondrial
reactant: 349036
product: 349072
kinetic law: 349084
notes: GENE_ASSOCIATION: ( YCL009C and YMR108W ) PROTEIN_ASSOCIATION: Ilv26-m SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 4.1.3.18
fast: false
reactant: 349048
product: 349060
reversible: false

349036
type: SpeciesReference
stoichiometry: 1.0
species: 284796

349072
type: SpeciesReference
stoichiometry: 1.0
species: 284001

291719
type: LocalParameter
value: 0.0

291717
type: LocalParameter
value: 0.161493

291715
type: LocalParameter
value: 0.0

291713
type: LocalParameter
value: 999999.0

291711
type: LocalParameter
value: 0.0

349048
type: SpeciesReference
stoichiometry: 2.0
species: 285949

349060
type: SpeciesReference
stoichiometry: 1.0
species: 283668

283668
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M__S__2_Acetolactate_C5H7O4

288917
type: Reaction
kinetic law: 379616
product: 379604
reactant: 379591
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Threonine_exchange

297066
type: LocalParameter
value: -0.039596

297064
type: LocalParameter
value: 0.0

297063
type: LocalParameter
value: 0.0

297062
type: LocalParameter
value: 999999.0

297060
type: LocalParameter
value: 0.0

379604
type: SpeciesReference
stoichiometry: 1.0
species: 287002

287002
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Threonine_C4H9NO3

379591
type: SpeciesReference
stoichiometry: 1.0
species: 286207

286207
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Threonine_C4H9NO3

289678
type: Reaction
notes: GENE_ASSOCIATION: YER019W PROTEIN_ASSOCIATION: Isc1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
kinetic law: 404881
product: 404844
name: R_inositol_phosphorylceramide__ceramide_2__26C__phospholipase_C
reactant: 404819
reversible: false
product: 404868
product: 404856
fast: false
reactant: 404832

299591
type: LocalParameter
value: -0.023758

299589
type: LocalParameter
value: 0.0

299588
type: LocalParameter
value: 0.0

299586
type: LocalParameter
value: 999999.0

299585
type: LocalParameter
value: 0.0

404844
type: SpeciesReference
stoichiometry: 1.0
species: 283920

404819
type: SpeciesReference
stoichiometry: 1.0
species: 284757

404868
type: SpeciesReference
stoichiometry: 1.0
species: 285309

404856
type: SpeciesReference
stoichiometry: 1.0
species: 284787

404832
type: SpeciesReference
stoichiometry: 0.01
species: 285074

289868
type: Reaction
kinetic law: 411424
product: 411412
reactant: 411400
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Nuclear PROTEIN_CLASS:
fast: false
reversible: true
name: R_1D_myo_Inositol_1_4_5_trisphosphate_nuclear_transport_via_diffusion

300286
type: LocalParameter
value: 0.0

300285
type: LocalParameter
value: 0.0

300283
type: LocalParameter
value: 0.0

300282
type: LocalParameter
value: 999999.0

300280
type: LocalParameter
value: -999999.0

411412
type: SpeciesReference
stoichiometry: 1.0
species: 285306

285306
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_1D_myo_Inositol_1_4_5_trisphosphate_C6H9O15P3

411400
type: SpeciesReference
stoichiometry: 1.0
species: 285303

285303
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_1D_myo_Inositol_1_4_5_trisphosphate_C6H9O15P3

289882
type: Reaction
name: R_Mannose__inositol_P_2_ceramide__ceramide_2__26C__phospholipase_C
product: 411813
kinetic law: 411849
reactant: 411789
product: 411825
reversible: false
reactant: 411801
product: 411837
notes: GENE_ASSOCIATION: YER019W PROTEIN_ASSOCIATION: Isc1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
fast: false

411813
type: SpeciesReference
stoichiometry: 1.0
species: 283920

300338
type: LocalParameter
value: -0.033063

300337
type: LocalParameter
value: 0.0

300335
type: LocalParameter
value: 0.0

300334
type: LocalParameter
value: 999999.0

300331
type: LocalParameter
value: 0.0

411789
type: SpeciesReference
stoichiometry: 1.0
species: 284757

411825
type: SpeciesReference
stoichiometry: 1.0
species: 284787

411801
type: SpeciesReference
stoichiometry: 0.01
species: 285330

411837
type: SpeciesReference
stoichiometry: 1.0
species: 285234

288563
type: Reaction
kinetic law: 375320
product: 375308
reactant: 375296
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Asparagine_exchange

296122
type: LocalParameter
value: -0.051673

296120
type: LocalParameter
value: 0.0

296119
type: LocalParameter
value: 0.0

296118
type: LocalParameter
value: 999999.0

296116
type: LocalParameter
value: 0.0

375308
type: SpeciesReference
stoichiometry: 1.0
species: 286648

286648
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Asparagine_C4H8N2O3

375296
type: SpeciesReference
stoichiometry: 1.0
species: 283785

283785
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Asparagine_C4H8N2O3

286024
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_sirohydrochlorin_C42H39N4O16

290768
type: Reaction
kinetic law: 440460
product: 440447
reactant: 440434
notes: GENE_ASSOCIATION: YPL244C PROTEIN_ASSOCIATION: Hut1-g SUBSYSTEM: S_Transport__Golgi_Apparatus PROTEIN_CLASS:
fast: false
reversible: false
name: R_UDPgalactose_transport__Golgi_apparatus_

303750
type: LocalParameter
value: -0.168681

303749
type: LocalParameter
value: 0.0

303747
type: LocalParameter
value: 0.0

303746
type: LocalParameter
value: 999999.0

303744
type: LocalParameter
value: 0.0

440447
type: SpeciesReference
stoichiometry: 1.0
species: 286453

286453
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282876
name: M_UDPgalactose_C15H22N2O17P2

440434
type: SpeciesReference
stoichiometry: 1.0
species: 286450

282938
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_1_Pyrroline_5_carboxylate_C5H6NO2

284933
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Tetrahydropteroyltri_L_glutamate_C24H34N8O12

284511
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_sn_Glycero_3_phosphocholine_C8H20NO6P

283125
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3_Carboxy_3_hydroxy_4_methylpentanoate_C7H10O5

284487
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Fructose_C6H12O6

287944
type: Reaction
name: R_Ceramide_1_synthase__24C_
reactant: 362675
kinetic law: 362736
fast: false
reactant: 362687
product: 362700
product: 362712
product: 362724
reversible: false
notes: GENE_ASSOCIATION: ( YKL008C or YHL003C ) PROTEIN_ASSOCIATION: ( Lac1 ) or ( Lag1 ) SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:

362675
type: SpeciesReference
stoichiometry: 1.0
species: 286069

293609
type: LocalParameter
value: -0.405269

293607
type: LocalParameter
value: 0.0

293605
type: LocalParameter
value: 0.0

293603
type: LocalParameter
value: 999999.0

293600
type: LocalParameter
value: 0.0

362687
type: SpeciesReference
stoichiometry: 1.0
species: 286393

286393
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

362700
type: SpeciesReference
stoichiometry: 1.0
species: 283902

362712
type: SpeciesReference
stoichiometry: 1.0
species: 284013

362724
type: SpeciesReference
stoichiometry: 1.0
species: 284787

288554
type: Reaction
kinetic law: 375211
product: 375199
reactant: 375187
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_Arabinose_exchange

296098
type: LocalParameter
value: 0.0

296096
type: LocalParameter
value: 0.0

296095
type: LocalParameter
value: 0.0

296094
type: LocalParameter
value: 999999.0

296092
type: LocalParameter
value: 0.0

375199
type: SpeciesReference
stoichiometry: 1.0
species: 286639

375187
type: SpeciesReference
stoichiometry: 1.0
species: 283752

283752
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Arabinose_C5H10O5

286774
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Glyoxylate_C2H1O3

288689
type: Reaction
kinetic law: 376845
product: 376832
reactant: 376820
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Glyoxylate_exchange

296458
type: LocalParameter
value: -0.011681

296456
type: LocalParameter
value: 0.0

296455
type: LocalParameter
value: 0.0

296454
type: LocalParameter
value: 999999.0

296452
type: LocalParameter
value: 0.0

376832
type: SpeciesReference
stoichiometry: 1.0
species: 286774

376820
type: SpeciesReference
stoichiometry: 1.0
species: 284651

284651
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Glyoxylate_C2H1O3

289323
type: Reaction
kinetic law: 393766
product: 393754
reactant: 393742
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Nuclear PROTEIN_CLASS:
fast: false
reversible: true
name: R_GDP_nuclear_transport

298376
type: LocalParameter
value: 0.0

298375
type: LocalParameter
value: 0.0

298373
type: LocalParameter
value: 0.0

298372
type: LocalParameter
value: 999999.0

298371
type: LocalParameter
value: -999999.0

393754
type: SpeciesReference
stoichiometry: 1.0
species: 284571

284571
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_GDP_C10H12N5O11P2

393742
type: SpeciesReference
stoichiometry: 1.0
species: 284562

288391
type: Reaction
kinetic law: 372364
product: 372352
reactant: 372340
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_erythrose_4_phosphate_mtiochondrial_transport_via_diffusion

295458
type: LocalParameter
value: 0.0

295455
type: LocalParameter
value: 0.076083

295452
type: LocalParameter
value: 0.0

295449
type: LocalParameter
value: 999999.0

295446
type: LocalParameter
value: -999999.0

372352
type: SpeciesReference
stoichiometry: 1.0
species: 284328

372340
type: SpeciesReference
stoichiometry: 1.0
species: 284325

285988
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Riboflavin_C17H20N4O6

287719
type: Reaction
notes: GENE_ASSOCIATION: YBR034C PROTEIN_ASSOCIATION: Hmt1 SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS:
product: 357510
reactant: 357462
fast: false
reversible: false
product: 357486
reactant: 357474
product: 357498
kinetic law: 357522
name: R_hnRNP_arginine_N_methyltransferase

357510
type: SpeciesReference
stoichiometry: 1.0
species: 284787

357462
type: SpeciesReference
stoichiometry: 1.0
species: 283695

357486
type: SpeciesReference
stoichiometry: 1.0
species: 283449

283449
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N_pai__Methyl_L_histidine_C7H11N3O2

357474
type: SpeciesReference
stoichiometry: 1.0
species: 284897

357498
type: SpeciesReference
stoichiometry: 1.0
species: 283626

292910
type: LocalParameter
value: -0.158188

292908
type: LocalParameter
value: 0.0

292906
type: LocalParameter
value: 0.0

292904
type: LocalParameter
value: 999999.0

292902
type: LocalParameter
value: 0.0

289457
type: Reaction
kinetic law: 398131
product: 398119
reactant: 398107
notes: GENE_ASSOCIATION: YJL212C PROTEIN_ASSOCIATION: Opt1 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: false
name: R_glutathione_transport

298835
type: LocalParameter
value: 0.0

298833
type: LocalParameter
value: 0.0

298832
type: LocalParameter
value: 0.0

298830
type: LocalParameter
value: 999999.0

298829
type: LocalParameter
value: 0.0

398119
type: SpeciesReference
stoichiometry: 1.0
species: 284720

398107
type: SpeciesReference
stoichiometry: 1.0
species: 284723

283884
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_CDP_C9H12N3O11P2

286894
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_NMN_C11H14N2O8P

287551
type: Reaction
product: 353695
notes: GENE_ASSOCIATION: ( YDR368W or YMR318C or YBR036C ) PROTEIN_ASSOCIATION: ( Ypr1 ) or ( Adh6 ) or ( Adh7 ) SUBSYSTEM: S_Complex_Alcohol_Metabolism PROTEIN_CLASS:
reactant: 353671
fast: false
reactant: 353683
reactant: 353659
product: 353707
kinetic law: 353719
name: R_aldehyde_dehydrogenase__2_methylbutanol__NADP_
reversible: false

353695
type: SpeciesReference
stoichiometry: 1.0
species: 283053

283053
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_methyl_1_butanol_C5H12O

353671
type: SpeciesReference
stoichiometry: 1.0
species: 284787

353683
type: SpeciesReference
stoichiometry: 1.0
species: 285436

353659
type: SpeciesReference
stoichiometry: 1.0
species: 283044

353707
type: SpeciesReference
stoichiometry: 1.0
species: 285421

292397
type: LocalParameter
value: -0.045734

292395
type: LocalParameter
value: 0.0

292393
type: LocalParameter
value: 0.0

292391
type: LocalParameter
value: 999999.0

292389
type: LocalParameter
value: 0.0

287200
type: Reaction
reactant: 346464
product: 346488
reactant: 346452
product: 346476
reversible: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Quinone_Biosynthesis PROTEIN_CLASS:
fast: false
name: R_4_hydroxybenzoate_formation
product: 346500
kinetic law: 346512

346464
type: SpeciesReference
stoichiometry: 1.0
species: 284766

346488
type: SpeciesReference
stoichiometry: 1.0
species: 284016

346452
type: SpeciesReference
stoichiometry: 1.0
species: 283308

283308
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_4_hydroxybenoyl_CoA_C28H36N7O18P3S

346476
type: SpeciesReference
stoichiometry: 1.0
species: 283305

346500
type: SpeciesReference
stoichiometry: 1.0
species: 284796

291342
type: LocalParameter
value: 0.0

291340
type: LocalParameter
value: 0.0

291338
type: LocalParameter
value: 0.0

291336
type: LocalParameter
value: 999999.0

291334
type: LocalParameter
value: 0.0

283980
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_3_Carboxy_3__methylammonio_propyl_L_histidine_C11H18N4O4

288328
type: Reaction
notes: GENE_ASSOCIATION: YNR043W PROTEIN_ASSOCIATION: Mvd1 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS: 4.1.1.33
product: 371081
product: 371045
reactant: 371021
product: 371057
kinetic law: 371094
reversible: false
fast: false
name: R_diphosphomevalonate_decarboxylase
product: 371069
reactant: 371033

371081
type: SpeciesReference
stoichiometry: 1.0
species: 285751

371045
type: SpeciesReference
stoichiometry: 1.0
species: 283602

371021
type: SpeciesReference
stoichiometry: 1.0
species: 283374

283374
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M__R__5_Diphosphomevalonate_C6H10O10P2

371057
type: SpeciesReference
stoichiometry: 1.0
species: 283992

295185
type: LocalParameter
value: 0.0

295182
type: LocalParameter
value: 0.0038

295179
type: LocalParameter
value: 0.0

295176
type: LocalParameter
value: 999999.0

295173
type: LocalParameter
value: 0.0

371069
type: SpeciesReference
stoichiometry: 1.0
species: 285083

371033
type: SpeciesReference
stoichiometry: 1.0
species: 283830

285970
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_alpha_D_Ribose_1_phosphate_C5H9O8P

288605
type: Reaction
kinetic law: 375826
product: 375814
reactant: 375802
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Deoxycytidine_exchange

296234
type: LocalParameter
value: -0.111266

296232
type: LocalParameter
value: 0.0

296231
type: LocalParameter
value: 0.0

296230
type: LocalParameter
value: 999999.0

296228
type: LocalParameter
value: 0.0

375814
type: SpeciesReference
stoichiometry: 1.0
species: 286690

375802
type: SpeciesReference
stoichiometry: 1.0
species: 284148

284148
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Deoxycytidine_C9H13N3O4

290104
type: Reaction
name: R_Alcohol_Acetyltransferase__isobutyl_alcohol_
reactant: 418780
fast: false
product: 418792
notes: GENE_ASSOCIATION: ( YOR377W or YGR177C ) PROTEIN_ASSOCIATION: ( Atf1 ) or ( Atf2 ) SUBSYSTEM: S_Complex_Alcohol_Metabolism PROTEIN_CLASS: 2.3.1.84
reversible: false
reactant: 418768
kinetic law: 418816
product: 418804

418780
type: SpeciesReference
stoichiometry: 1.0
species: 284975

418792
type: SpeciesReference
stoichiometry: 1.0
species: 284013

418768
type: SpeciesReference
stoichiometry: 1.0
species: 283521

301275
type: LocalParameter
value: 0.0

301273
type: LocalParameter
value: 0.0

301272
type: LocalParameter
value: 0.0

301271
type: LocalParameter
value: 999999.0

301269
type: LocalParameter
value: 0.0

418804
type: SpeciesReference
stoichiometry: 1.0
species: 284969

284969
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_isobutyl_acetate_C6H12O2

288947
type: Reaction
kinetic law: 379978
product: 379966
reactant: 379954
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Valine_exchange

297145
type: LocalParameter
value: -0.011285

297143
type: LocalParameter
value: 0.0

297142
type: LocalParameter
value: 0.0

297141
type: LocalParameter
value: 999999.0

297139
type: LocalParameter
value: 0.0

379966
type: SpeciesReference
stoichiometry: 1.0
species: 287032

287032
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Valine_C5H11NO2

379954
type: SpeciesReference
stoichiometry: 1.0
species: 286498

290826
type: Reaction
reversible: false
reactant: 442292
product: 442328
name: R_xanthosine_transport_in_via_proton_symport
product: 442316
kinetic law: 442340
fast: false
reactant: 442304
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:

442292
type: SpeciesReference
stoichiometry: 1.0
species: 284790

442328
type: SpeciesReference
stoichiometry: 1.0
species: 286519

286519
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Xanthosine_C10H12N4O6

442316
type: SpeciesReference
stoichiometry: 1.0
species: 284787

303953
type: LocalParameter
value: 0.0

303952
type: LocalParameter
value: 0.0

303950
type: LocalParameter
value: 0.0

303949
type: LocalParameter
value: 999999.0

303947
type: LocalParameter
value: 0.0

442304
type: SpeciesReference
stoichiometry: 1.0
species: 286522

286522
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Xanthosine_C10H12N4O6

290840
type: Reaction
reactant: 442703
notes: GENE_ASSOCIATION: YCR048W PROTEIN_ASSOCIATION: Are1 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS:
reactant: 442763
reactant: 442715
name: R_Acyl_CoAzymosterol_acyltransferase__yeast_specific
fast: false
reactant: 442751
product: 442787
reactant: 442727
reactant: 442739
reversible: false
kinetic law: 442811
reactant: 442775
product: 442799

442703
type: SpeciesReference
stoichiometry: 0.655
species: 284846

442763
type: SpeciesReference
stoichiometry: 0.015
species: 286150

442715
type: SpeciesReference
stoichiometry: 0.01
species: 284876

442751
type: SpeciesReference
stoichiometry: 0.03
species: 286099

442787
type: SpeciesReference
stoichiometry: 1.0
species: 284013

442727
type: SpeciesReference
stoichiometry: 0.27
species: 285577

442739
type: SpeciesReference
stoichiometry: 0.02
species: 285775

304002
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value: 0.0

304001
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value: 0.0

303999
type: LocalParameter
value: 0.0

303998
type: LocalParameter
value: 999999.0

303996
type: LocalParameter
value: 0.0

442775
type: SpeciesReference
stoichiometry: 0.01
species: 286549

442799
type: SpeciesReference
stoichiometry: 0.01
species: 286555

286555
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

289502
type: Reaction
notes: GENE_ASSOCIATION: YKR009C PROTEIN_ASSOCIATION: Fox2-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 1.1.1.35
product: 399349
name: R_3_Hydroxyacyl_CoA_dehydrogenase__3_oxotetradecanoyl_CoA___peroxisomal
kinetic law: 399373
fast: false
reactant: 399313
product: 399361
reactant: 399337
reactant: 399325
reversible: true

399349
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stoichiometry: 1.0
species: 283173

298978
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value: 0.0

298976
type: LocalParameter
value: 0.0

298975
type: LocalParameter
value: 0.0

298973
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value: 999999.0

298972
type: LocalParameter
value: -999999.0

399313
type: SpeciesReference
stoichiometry: 1.0
species: 283230

399361
type: SpeciesReference
stoichiometry: 1.0
species: 285406

399337
type: SpeciesReference
stoichiometry: 1.0
species: 285418

399325
type: SpeciesReference
stoichiometry: 1.0
species: 284808

288467
type: Reaction
kinetic law: 374161
product: 374149
reactant: 374137
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_ethanolamine_transport_via_diffusion__extracellular_

295796
type: LocalParameter
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295793
type: LocalParameter
value: 0.0

295790
type: LocalParameter
value: 0.0

295787
type: LocalParameter
value: 999999.0

295784
type: LocalParameter
value: -999999.0

374149
type: SpeciesReference
stoichiometry: 1.0
species: 284379

284379
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ethanolamine_C2H8NO

374137
type: SpeciesReference
stoichiometry: 1.0
species: 284382

284382
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Ethanolamine_C2H8NO

289586
type: Reaction
notes: GENE_ASSOCIATION: YHR037W PROTEIN_ASSOCIATION: Put2-m SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.12
product: 402121
reactant: 402097
name: R_L_hydroxyproline_dehydrogenase__NAD___mitochondrial
product: 402133
product: 402109
fast: false
reactant: 402084
kinetic law: 402146
reversible: false

402121
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stoichiometry: 2.0
species: 284796

402097
type: SpeciesReference
stoichiometry: 1.0
species: 285399

402133
type: SpeciesReference
stoichiometry: 1.0
species: 285412

402109
type: SpeciesReference
stoichiometry: 1.0
species: 282932

402084
type: SpeciesReference
stoichiometry: 1.0
species: 283317

283317
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_trans_4_Hydroxy_L_proline_C5H9NO3

299269
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value: -0.004158

299267
type: LocalParameter
value: 0.0

299266
type: LocalParameter
value: 0.0

299264
type: LocalParameter
value: 999999.0

299263
type: LocalParameter
value: 0.0

283749
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Arabinose_C5H10O5

290266
type: Reaction
product: 423937
product: 423865
reactant: 423829
product: 423901
name: R_phospholipase_B__phosphatidylcholine___yeast_specific
product: 423841
reversible: false
product: 423889
product: 423925
notes: GENE_ASSOCIATION: YML059C PROTEIN_ASSOCIATION: Nte1 SUBSYSTEM: S_Phospholipid_Metabolism PROTEIN_CLASS:
product: 423853
product: 423949
fast: false
kinetic law: 423961
product: 423913
product: 423877
reactant: 423817

423937
type: SpeciesReference
stoichiometry: 0.09
species: 285550

285550
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_octadecadienoate__n_C182__C18H31O2

423865
type: SpeciesReference
stoichiometry: 0.5
species: 284508

284508
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_sn_Glycero_3_phosphocholine_C8H20NO6P

423829
type: SpeciesReference
stoichiometry: 0.005
species: 285670

423901
type: SpeciesReference
stoichiometry: 0.17
species: 284837

423841
type: SpeciesReference
stoichiometry: 0.02
species: 284115

284115
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Decanoate__n_C100__C10H19O2

423889
type: SpeciesReference
stoichiometry: 0.27
species: 284828

423925
type: SpeciesReference
stoichiometry: 0.24
species: 285538

423853
type: SpeciesReference
stoichiometry: 0.06
species: 284160

423949
type: SpeciesReference
stoichiometry: 0.1
species: 286402

301984
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value: 0.0

301983
type: LocalParameter
value: 0.0

301981
type: LocalParameter
value: 0.0

301980
type: LocalParameter
value: 999999.0

301978
type: LocalParameter
value: 0.0

423913
type: SpeciesReference
stoichiometry: 0.05
species: 285529

423877
type: SpeciesReference
stoichiometry: 1.0
species: 284787

423817
type: SpeciesReference
stoichiometry: 1.0
species: 284757

287809
type: Reaction
product: 359554
fast: false
product: 359578
product: 359566
reversible: false
reactant: 359530
name: R_ATP_diphosphohydrolase
reactant: 359542
kinetic law: 359590
notes: GENE_ASSOCIATION: YER005W PROTEIN_ASSOCIATION: Ynd1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.6.1.5

359554
type: SpeciesReference
stoichiometry: 1.0
species: 283713

359578
type: SpeciesReference
stoichiometry: 2.0
species: 285751

359566
type: SpeciesReference
stoichiometry: 2.0
species: 284787

359530
type: SpeciesReference
stoichiometry: 1.0
species: 283830

359542
type: SpeciesReference
stoichiometry: 2.0
species: 284757

293182
type: LocalParameter
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293180
type: LocalParameter
value: 0.0

293178
type: LocalParameter
value: 0.0

293176
type: LocalParameter
value: 999999.0

293174
type: LocalParameter
value: 0.0

285673
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870

289243
type: Reaction
product: 391147
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Glycoprotein_Metabolism PROTEIN_CLASS: 2.4.1.132
reactant: 391110
product: 391134
reversible: false
name: R_Glycolipid_1_3_alpha_D_mannosyltransferase__Golgi_apparatus
kinetic law: 391159
fast: false
product: 391122
reactant: 391098

391147
type: SpeciesReference
stoichiometry: 1.0
species: 285186

285186
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282876

391110
type: SpeciesReference
stoichiometry: 1.0
species: 285198

285198
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282876

391134
type: SpeciesReference
stoichiometry: 1.0
species: 284793

298116
type: LocalParameter
value: 0.0

298115
type: LocalParameter
value: 0.0

298113
type: LocalParameter
value: 0.0

298112
type: LocalParameter
value: 999999.0

298110
type: LocalParameter
value: 0.0

391122
type: SpeciesReference
stoichiometry: 1.0
species: 284565

284565
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282876
name: M_GDP_C10H12N5O11P2

391098
type: SpeciesReference
stoichiometry: 1.0
species: 284577

284577
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282876
name: M_GDP_D_mannose_C16H23N5O16P2

286771
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Glutamate_C5H8NO4

285589
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Oxo_3_hydroxy_4_phosphobutanoate_C4H4O8P

290528
type: Reaction
notes: GENE_ASSOCIATION: YHR104W PROTEIN_ASSOCIATION: Gre3 SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.21
reactant: 432548
product: 432572
reactant: 432524
reversible: false
kinetic law: 432585
fast: false
reactant: 432536
product: 432560
name: R_D_sorbitol_reductase

432548
type: SpeciesReference
stoichiometry: 1.0
species: 285436

432572
type: SpeciesReference
stoichiometry: 1.0
species: 286012

286012
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Sorbitol_C6H14O6

432524
type: SpeciesReference
stoichiometry: 1.0
species: 284586

302900
type: LocalParameter
value: 0.0

302898
type: LocalParameter
value: 0.0

302897
type: LocalParameter
value: 0.0

302895
type: LocalParameter
value: 999999.0

302894
type: LocalParameter
value: 0.0

432536
type: SpeciesReference
stoichiometry: 1.0
species: 284787

432560
type: SpeciesReference
stoichiometry: 1.0
species: 285421

287008
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Thymidine_C10H14N2O5

283539
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_N_Acetyl_L_glutamyl_5_phosphate_C7H9NO8P

290732
type: Reaction
reactant: 439314
fast: false
reactant: 439338
product: 439362
product: 439374
product: 439350
name: R_Tryptophanyl_tRNA_synthetase__mitochondrial
notes: GENE_ASSOCIATION: YDR268W PROTEIN_ASSOCIATION: Msw1-m SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.2
reversible: false
kinetic law: 439386
reactant: 439326

439314
type: SpeciesReference
stoichiometry: 1.0
species: 283836

439338
type: SpeciesReference
stoichiometry: 1.0
species: 286378

286378
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Tryptophan_C11H12N2O2

439362
type: SpeciesReference
stoichiometry: 1.0
species: 285799

439374
type: SpeciesReference
stoichiometry: 1.0
species: 286384

286384
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Tryptophanyl_tRNA_Trp__C11H11N2OR

439350
type: SpeciesReference
stoichiometry: 1.0
species: 283716

303624
type: LocalParameter
value: -0.147101

303623
type: LocalParameter
value: 0.0

303621
type: LocalParameter
value: 0.0

303620
type: LocalParameter
value: 999999.0

303618
type: LocalParameter
value: 0.0

439326
type: SpeciesReference
stoichiometry: 1.0
species: 286357

286357
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_tRNA_Trp__R

286570
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_2_methylbutyraldehyde_C5H10O

287749
type: Reaction
reversible: false
notes: GENE_ASSOCIATION: ( YKL146W or YNL101W ) PROTEIN_ASSOCIATION: ( Avt3-v ) or ( Avt4-v ) SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
fast: false
kinetic law: 358258
name: R_L_asparagine_transport_out_via_proton_symport__vacuolar
reactant: 358209
product: 358233
product: 358246
reactant: 358221

293000
type: LocalParameter
value: 0.0

292998
type: LocalParameter
value: 0.0

292996
type: LocalParameter
value: 0.0

292994
type: LocalParameter
value: 999999.0

292992
type: LocalParameter
value: 0.0

358209
type: SpeciesReference
stoichiometry: 1.0
species: 283791

283791
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_L_Asparagine_C4H8N2O3

358233
type: SpeciesReference
stoichiometry: 1.0
species: 283782

358246
type: SpeciesReference
stoichiometry: 1.0
species: 284787

358221
type: SpeciesReference
stoichiometry: 1.0
species: 284805

289377
type: Reaction
fast: false
reversible: false
product: 395483
name: R_Glucokinase
product: 395495
kinetic law: 395507
notes: GENE_ASSOCIATION: YCL040W PROTEIN_ASSOCIATION: Glk1 SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 2.7.1.2
reactant: 395447
product: 395471
reactant: 395459

395483
type: SpeciesReference
stoichiometry: 1.0
species: 284520

395495
type: SpeciesReference
stoichiometry: 1.0
species: 284787

298558
type: LocalParameter
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298557
type: LocalParameter
value: 0.0

298555
type: LocalParameter
value: 0.0

298554
type: LocalParameter
value: 999999.0

298552
type: LocalParameter
value: 0.0

395447
type: SpeciesReference
stoichiometry: 1.0
species: 283830

395471
type: SpeciesReference
stoichiometry: 1.0
species: 283602

395459
type: SpeciesReference
stoichiometry: 1.0
species: 284586

283122
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3_Carboxy_2_hydroxy_4_methylpentanoate_C7H10O5

286687
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Decanoate__n_C100__C10H19O2

288512
type: Reaction
kinetic law: 374704
product: 374692
reactant: 374680
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_5_Amino_4_oxopentanoate_exchange

295980
type: LocalParameter
value: 0.0

295978
type: LocalParameter
value: 0.0

295977
type: LocalParameter
value: 0.0

295976
type: LocalParameter
value: 999999.0

295974
type: LocalParameter
value: 0.0

374692
type: SpeciesReference
stoichiometry: 1.0
species: 286597

286597
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_5_Amino_4_oxopentanoate_C5H9NO3

374680
type: SpeciesReference
stoichiometry: 1.0
species: 283365

283365
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_5_Amino_4_oxopentanoate_C5H9NO3

284784
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3_Hydroxy_L_kynurenine_C10H12N2O4

289780
type: Reaction
kinetic law: 408530
product: 408518
reactant: 408506
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 5.2.1.2
fast: false
reversible: false
name: R_maleylacetoacetate_isomerase

299956
type: LocalParameter
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299954
type: LocalParameter
value: 0.0

299953
type: LocalParameter
value: 0.0

299951
type: LocalParameter
value: 999999.0

299950
type: LocalParameter
value: 0.0

408518
type: SpeciesReference
stoichiometry: 1.0
species: 283284

408506
type: SpeciesReference
stoichiometry: 1.0
species: 283326

283326
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Maleylacetoacetate_C8H6O6

288647
type: Reaction
kinetic law: 376333
product: 376321
reactant: 376309
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_fecosterol_ester__yeast_specific_exchange

296346
type: LocalParameter
value: -32.49596

296344
type: LocalParameter
value: 0.0

296343
type: LocalParameter
value: 0.0

296342
type: LocalParameter
value: 999999.0

296340
type: LocalParameter
value: 0.0

376321
type: SpeciesReference
stoichiometry: 1.0
species: 286732

286732
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870

376309
type: SpeciesReference
stoichiometry: 1.0
species: 284439

284439
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870

283704
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_S_Adenosylmethioninamine_C14H24N6O3S

288358
type: Reaction
name: R_deoxyuridine_phosphorylase
kinetic law: 371735
product: 371711
notes: GENE_ASSOCIATION: YLR209C PROTEIN_ASSOCIATION: Pnp1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS:
reversible: true
reactant: 371699
fast: false
product: 371723
reactant: 371687

295315
type: LocalParameter
value: 0.0

295312
type: LocalParameter
value: 0.0

295309
type: LocalParameter
value: 0.0

295306
type: LocalParameter
value: 999999.0

295303
type: LocalParameter
value: -999999.0

371711
type: SpeciesReference
stoichiometry: 1.0
species: 283002

283002
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Deoxy_D_ribose_1_phosphate_C5H9O7P

371699
type: SpeciesReference
stoichiometry: 1.0
species: 285751

371723
type: SpeciesReference
stoichiometry: 1.0
species: 286468

286468
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Uracil_C4H4N2O2

371687
type: SpeciesReference
stoichiometry: 1.0
species: 284307

289528
type: Reaction
kinetic law: 400191
product: 400179
reactant: 400167
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: false
name: R_Hexadecanoate__n_C160__transport_in_via_uniport

299066
type: LocalParameter
value: 0.0

299065
type: LocalParameter
value: 0.0

299063
type: LocalParameter
value: 0.0

299062
type: LocalParameter
value: 999999.0

299060
type: LocalParameter
value: 0.0

400179
type: SpeciesReference
stoichiometry: 1.0
species: 284828

400167
type: SpeciesReference
stoichiometry: 1.0
species: 284831

284831
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Hexadecanoate__n_C160__C16H31O2

289542
type: Reaction
fast: false
product: 400651
reactant: 400615
name: R_hexokinase__D_fructoseATP_
reactant: 400627
kinetic law: 400676
product: 400664
product: 400639
notes: GENE_ASSOCIATION: ( YFR053C or YGL253W ) PROTEIN_ASSOCIATION: ( Hxk1 ) or ( Hxk2 ) SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 2.7.1.1
reversible: false

400651
type: SpeciesReference
stoichiometry: 1.0
species: 284403

400615
type: SpeciesReference
stoichiometry: 1.0
species: 283830

400627
type: SpeciesReference
stoichiometry: 1.0
species: 284487

299117
type: LocalParameter
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299115
type: LocalParameter
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299114
type: LocalParameter
value: 0.0

299112
type: LocalParameter
value: 999999.0

299109
type: LocalParameter
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400664
type: SpeciesReference
stoichiometry: 1.0
species: 284787

400639
type: SpeciesReference
stoichiometry: 1.0
species: 283602

289495
type: Reaction
kinetic law: 399083
product: 399071
reactant: 399059
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
fast: false
reversible: true
name: R_H2O_transport__vacuolar

298950
type: LocalParameter
value: 0.0

298949
type: LocalParameter
value: 0.0

298947
type: LocalParameter
value: 0.0

298946
type: LocalParameter
value: 999999.0

298945
type: LocalParameter
value: -999999.0

399071
type: SpeciesReference
stoichiometry: 1.0
species: 284775

284775
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_H2O_H2O

399059
type: SpeciesReference
stoichiometry: 1.0
species: 284757

284544
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Glucosamine_6_phosphate_C6H13NO8P

290316
type: Reaction
reversible: false
product: 425701
product: 425689
fast: false
product: 425713
reactant: 425664
kinetic law: 425725
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 1.3.1.12
reactant: 425676
name: R_prephenate_dehydrogenase

425701
type: SpeciesReference
stoichiometry: 1.0
species: 283992

425689
type: SpeciesReference
stoichiometry: 1.0
species: 283101

425713
type: SpeciesReference
stoichiometry: 1.0
species: 285409

425664
type: SpeciesReference
stoichiometry: 1.0
species: 285396

302158
type: LocalParameter
value: -0.004158

302156
type: LocalParameter
value: 0.0

302155
type: LocalParameter
value: 0.0

302153
type: LocalParameter
value: 999999.0

302152
type: LocalParameter
value: 0.0

425676
type: SpeciesReference
stoichiometry: 1.0
species: 285793

286978
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Spermine_C10H30N4

289494
type: Reaction
kinetic law: 399047
product: 399035
reactant: 399023
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: true
name: R_H2O_transport__peroxisomal

298944
type: LocalParameter
value: 0.0

298942
type: LocalParameter
value: 0.0

298941
type: LocalParameter
value: 0.0

298939
type: LocalParameter
value: 999999.0

298938
type: LocalParameter
value: -999999.0

399035
type: SpeciesReference
stoichiometry: 1.0
species: 284778

399023
type: SpeciesReference
stoichiometry: 1.0
species: 284757

288049
type: Reaction
notes: GENE_ASSOCIATION: YLR151C PROTEIN_ASSOCIATION: Pcd1-p SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS:
reactant: 364935
fast: false
reversible: false
name: R_CoA_hydrolase__peroxisomal_
reactant: 364923
product: 364959
kinetic law: 364984
product: 364947
product: 364972

364935
type: SpeciesReference
stoichiometry: 1.0
species: 284778

364923
type: SpeciesReference
stoichiometry: 1.0
species: 284025

364959
type: SpeciesReference
stoichiometry: 1.0
species: 285646

285646
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Pantetheine_4__phosphate_C11H21N2O7PS

293975
type: LocalParameter
value: 0.0

293972
type: LocalParameter
value: 0.0

293969
type: LocalParameter
value: 0.0

293966
type: LocalParameter
value: 999999.0

293963
type: LocalParameter
value: 0.0

364947
type: SpeciesReference
stoichiometry: 2.0
species: 284808

364972
type: SpeciesReference
stoichiometry: 1.0
species: 285664

285664
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

283881
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_Carbamoyl_phosphate_CH2NO5P

283797
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879

289668
type: Reaction
fast: false
reversible: false
name: R_inositol_transport_in_via_proton_symport
product: 404496
reactant: 404483
reactant: 404470
notes: GENE_ASSOCIATION: ( YDR497C or YOL103W ) PROTEIN_ASSOCIATION: ( Itr1 ) or ( Itr2 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
product: 404508
kinetic law: 404521

404496
type: SpeciesReference
stoichiometry: 1.0
species: 284787

404483
type: SpeciesReference
stoichiometry: 1.0
species: 285056

285056
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_myo_Inositol_C6H12O6

404470
type: SpeciesReference
stoichiometry: 1.0
species: 284790

404508
type: SpeciesReference
stoichiometry: 1.0
species: 285053

299556
type: LocalParameter
value: 0.0

299554
type: LocalParameter
value: 0.0

299553
type: LocalParameter
value: 0.0

299551
type: LocalParameter
value: 999999.0

299550
type: LocalParameter
value: 0.0

288977
type: Reaction
kinetic law: 380378
product: 380366
reactant: 380354
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acid_peroxisomal_transport

297225
type: LocalParameter
value: -0.080183

297223
type: LocalParameter
value: 0.0

297222
type: LocalParameter
value: 0.0

297221
type: LocalParameter
value: 999999.0

297219
type: LocalParameter
value: 0.0

380366
type: SpeciesReference
stoichiometry: 1.0
species: 284166

284166
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Dodecanoate__n_C120__C12H23O2

380354
type: SpeciesReference
stoichiometry: 1.0
species: 284160

285023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Isoleucyl_tRNA_Ile__C6H12NOR

282990
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Deoxy_D_glucose_C6H12O5

288539
type: Reaction
kinetic law: 375031
product: 375019
reactant: 375007
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_Oxoglutarate_exchange

296052
type: LocalParameter
value: -0.019402

296050
type: LocalParameter
value: 0.0

296049
type: LocalParameter
value: 0.0

296048
type: LocalParameter
value: 999999.0

296046
type: LocalParameter
value: 0.0

375019
type: SpeciesReference
stoichiometry: 1.0
species: 286624

375007
type: SpeciesReference
stoichiometry: 1.0
species: 283644

290568
type: Reaction
kinetic law: 433858
product: 433846
reactant: 433833
notes: GENE_ASSOCIATION: ( YBR294W or YLR092W or YGR125W ) PROTEIN_ASSOCIATION: ( Sul1 ) or ( Sul2 ) or ( Sul3 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: false
name: R_sulfate_irreversible_uniport

303040
type: LocalParameter
value: 0.0

303038
type: LocalParameter
value: 0.022252

303037
type: LocalParameter
value: 0.0

303035
type: LocalParameter
value: 999999.0

303034
type: LocalParameter
value: 0.0

433846
type: SpeciesReference
stoichiometry: 1.0
species: 286057

433833
type: SpeciesReference
stoichiometry: 1.0
species: 286060

286060
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Sulfate_O4S

284894
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Homoisocitrate_C7H7O7

287449
type: Reaction
reversible: false
fast: false
reactant: 351406
name: R_adenosine_kinase
product: 351418
product: 351430
reactant: 351394
kinetic law: 351454
product: 351442
notes: GENE_ASSOCIATION: YJR105W PROTEIN_ASSOCIATION: Ado1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.1.20

351406
type: SpeciesReference
stoichiometry: 1.0
species: 283830

351418
type: SpeciesReference
stoichiometry: 1.0
species: 283602

351430
type: SpeciesReference
stoichiometry: 1.0
species: 283713

351394
type: SpeciesReference
stoichiometry: 1.0
species: 283593

292089
type: LocalParameter
value: 0.0

292087
type: LocalParameter
value: 0.005383

292085
type: LocalParameter
value: 0.0

292083
type: LocalParameter
value: 999999.0

292081
type: LocalParameter
value: 0.0

351442
type: SpeciesReference
stoichiometry: 1.0
species: 284787

287893
type: Reaction
kinetic law: 361671
product: 361659
product: 361647
reactant: 361635
notes: GENE_ASSOCIATION: YDR256C PROTEIN_ASSOCIATION: Cta1-p SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 1.11.1.6
fast: false
reversible: false
name: R_catalase_A__peroxisomal

293438
type: LocalParameter
value: 0.0

293436
type: LocalParameter
value: 0.0

293434
type: LocalParameter
value: 0.0

293432
type: LocalParameter
value: 999999.0

293430
type: LocalParameter
value: 0.0

361659
type: SpeciesReference
stoichiometry: 1.0
species: 285499

361647
type: SpeciesReference
stoichiometry: 2.0
species: 284778

361635
type: SpeciesReference
stoichiometry: 2.0
species: 284754

290808
type: Reaction
kinetic law: 441772
name: R_UTPUMP_antiport
product: 441748
reactant: 441700
fast: false
product: 441760
reactant: 441712
notes: GENE_ASSOCIATION: YBR192W PROTEIN_ASSOCIATION: Rim2-m SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
product: 441736
reactant: 441724
reversible: false

303890
type: LocalParameter
value: -0.029697

303889
type: LocalParameter
value: 0.0

303887
type: LocalParameter
value: 0.0

303886
type: LocalParameter
value: 999999.0

303884
type: LocalParameter
value: 0.0

441748
type: SpeciesReference
stoichiometry: 2.0
species: 284796

441700
type: SpeciesReference
stoichiometry: 2.0
species: 284787

441760
type: SpeciesReference
stoichiometry: 1.0
species: 286492

286492
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_UTP_C9H11N2O15P3

441712
type: SpeciesReference
stoichiometry: 1.0
species: 286489

286489
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_UTP_C9H11N2O15P3

441736
type: SpeciesReference
stoichiometry: 1.0
species: 286456

441724
type: SpeciesReference
stoichiometry: 1.0
species: 286459

286459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_UMP_C9H11N2O9P

288905
type: Reaction
kinetic law: 379470
product: 379458
reactant: 379446
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Taurine_exchange

297034
type: LocalParameter
value: 0.0

297032
type: LocalParameter
value: 0.0

297031
type: LocalParameter
value: 0.0

297030
type: LocalParameter
value: 999999.0

297028
type: LocalParameter
value: 0.0

379458
type: SpeciesReference
stoichiometry: 1.0
species: 286990

286990
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Taurine_C2H7NO3S

379446
type: SpeciesReference
stoichiometry: 1.0
species: 286138

286138
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Taurine_C2H7NO3S

289307
type: Reaction
kinetic law: 393247
reactant: 393187
product: 393223
name: R_glycine_cleavage_complex__lipoamide___mitochondrial
reversible: true
fast: false
reactant: 393199
product: 393235
reactant: 393211
notes: GENE_ASSOCIATION: ( YDR019C and YMR189W and YAL044C and YFL018C ) PROTEIN_ASSOCIATION: ( Gcv1-m and Gcv2-m and Gcv3-m and PdE3-m ) SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 1.4.4.2

298324
type: LocalParameter
value: 0.0

298323
type: LocalParameter
value: 0.0

298321
type: LocalParameter
value: 0.0

298320
type: LocalParameter
value: 999999.0

298319
type: LocalParameter
value: -999999.0

393187
type: SpeciesReference
stoichiometry: 1.0
species: 284663

393223
type: SpeciesReference
stoichiometry: 1.0
species: 283689

393199
type: SpeciesReference
stoichiometry: 1.0
species: 284796

393235
type: SpeciesReference
stoichiometry: 1.0
species: 284001

393211
type: SpeciesReference
stoichiometry: 1.0
species: 285162

290272
type: Reaction
kinetic law: 424229
product: 424217
reactant: 424205
notes: GENE_ASSOCIATION: YFL045C PROTEIN_ASSOCIATION: Sec53 SUBSYSTEM: S_Fructose_and_Mannose_Metabolism PROTEIN_CLASS: 5.4.2.8
fast: false
reversible: true
name: R_phosphomannomutase

302005
type: LocalParameter
value: 0.0

302004
type: LocalParameter
value: -0.232567

302002
type: LocalParameter
value: 0.0

302001
type: LocalParameter
value: 999999.0

301999
type: LocalParameter
value: -999999.0

424217
type: SpeciesReference
stoichiometry: 1.0
species: 285237

424205
type: SpeciesReference
stoichiometry: 1.0
species: 285231

289321
type: Reaction
product: 393718
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Golgi_Apparatus PROTEIN_CLASS:
kinetic law: 393730
reversible: true
reactant: 393694
name: R_GDP_Golgi_transport_via_proton_anitport
reactant: 393682
fast: false
product: 393706

393718
type: SpeciesReference
stoichiometry: 1.0
species: 284793

298370
type: LocalParameter
value: 0.0

298368
type: LocalParameter
value: 0.0

298367
type: LocalParameter
value: 0.0

298365
type: LocalParameter
value: 999999.0

298364
type: LocalParameter
value: -999999.0

393694
type: SpeciesReference
stoichiometry: 1.0
species: 284565

393682
type: SpeciesReference
stoichiometry: 1.0
species: 284787

393706
type: SpeciesReference
stoichiometry: 1.0
species: 284562

289259
type: Reaction
reactant: 391581
name: R_L_glutamate_5_semialdehyde_dehydratase__reversible
product: 391617
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS:
kinetic law: 391629
product: 391593
product: 391605
fast: false
reversible: true

391581
type: SpeciesReference
stoichiometry: 1.0
species: 284612

391617
type: SpeciesReference
stoichiometry: 1.0
species: 284757

298168
type: LocalParameter
value: 0.0

298167
type: LocalParameter
value: 0.047411

298165
type: LocalParameter
value: 0.0

298164
type: LocalParameter
value: 999999.0

298163
type: LocalParameter
value: -999999.0

391593
type: SpeciesReference
stoichiometry: 1.0
species: 282935

282935
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_1_Pyrroline_5_carboxylate_C5H6NO2

391605
type: SpeciesReference
stoichiometry: 1.0
species: 284787

289862
type: Reaction
product: 411232
reactant: 411182
fast: false
product: 411219
name: R_inositol_1_4_5_6__tetrakisphosphate_3_kinase__nucleus
reactant: 411195
product: 411207
reversible: false
notes: GENE_ASSOCIATION: YDR173C PROTEIN_ASSOCIATION: Arg82-n SUBSYSTEM: S_Phospholipid_Biosynthesis PROTEIN_CLASS: 2.7.1.151
kinetic law: 411244

411232
type: SpeciesReference
stoichiometry: 1.0
species: 285294

285294
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_1D_myo_Inositol_1_3_4_5_6_pentakisphosphate_C6H7O21P5

411182
type: SpeciesReference
stoichiometry: 1.0
species: 283839

283839
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_ATP_C10H12N5O13P3

411219
type: SpeciesReference
stoichiometry: 1.0
species: 284799

411195
type: SpeciesReference
stoichiometry: 1.0
species: 285300

285300
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_1D_myo_Inositol_1_4_5_6_tetrakisphosphate_C6H8O18P4

411207
type: SpeciesReference
stoichiometry: 1.0
species: 283611

283611
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_ADP_C10H12N5O10P2

300265
type: LocalParameter
value: 0.0

300264
type: LocalParameter
value: 0.0

300262
type: LocalParameter
value: 0.0

300261
type: LocalParameter
value: 999999.0

300259
type: LocalParameter
value: 0.0

289273
type: Reaction
kinetic law: 392099
product: 392086
reactant: 392074
notes: GENE_ASSOCIATION: YBR196C PROTEIN_ASSOCIATION: Pgi1 SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 5.3.1.9
fast: false
reversible: true
name: R_Glucose_6_phosphate_isomerase

298214
type: LocalParameter
value: 0.0

298212
type: LocalParameter
value: 0.0

298211
type: LocalParameter
value: 0.0

298209
type: LocalParameter
value: 999999.0

298208
type: LocalParameter
value: -999999.0

392086
type: SpeciesReference
stoichiometry: 1.0
species: 284520

392074
type: SpeciesReference
stoichiometry: 1.0
species: 284523

286042
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Siroheme_C42H36FeN4O16

286810
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Histidine_C6H9N3O2

290224
type: Reaction
reactant: 422322
product: 422334
product: 422358
reactant: 422298
reversible: false
kinetic law: 422370
product: 422346
reactant: 422310
name: R_Phenylalanyl_tRNA_synthetase
notes: GENE_ASSOCIATION: ( YFL022C and YLR060W ) PROTEIN_ASSOCIATION: Frs SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.20
fast: false

422322
type: SpeciesReference
stoichiometry: 1.0
species: 286336

286336
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_tRNA_Phe__R

422334
type: SpeciesReference
stoichiometry: 1.0
species: 283713

422358
type: SpeciesReference
stoichiometry: 1.0
species: 285796

422298
type: SpeciesReference
stoichiometry: 1.0
species: 283830

301820
type: LocalParameter
value: -0.095427

301819
type: LocalParameter
value: 0.0

301816
type: LocalParameter
value: 0.0

301815
type: LocalParameter
value: 999999.0

301812
type: LocalParameter
value: 0.0

422346
type: SpeciesReference
stoichiometry: 1.0
species: 285736

285736
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Phenylalanyl_tRNA_Phe__C9H10NOR

422310
type: SpeciesReference
stoichiometry: 1.0
species: 285718

290572
type: Reaction
kinetic law: 433942
product: 433930
product: 433918
reactant: 433906
notes: GENE_ASSOCIATION: YDR294C PROTEIN_ASSOCIATION: Dpl1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
fast: false
reversible: false
name: R_sphinganine_phosphate_lyase

303054
type: LocalParameter
value: 0.0

303052
type: LocalParameter
value: 0.0

303051
type: LocalParameter
value: 0.0

303049
type: LocalParameter
value: 999999.0

303048
type: LocalParameter
value: 0.0

433930
type: SpeciesReference
stoichiometry: 1.0
species: 284945

284945
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Hexadecanal_C16H32O

433918
type: SpeciesReference
stoichiometry: 1.0
species: 284385

433906
type: SpeciesReference
stoichiometry: 1.0
species: 286063

286063
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Sphinganine_1_phosphate_C18H39NO5P

290762
type: Reaction
notes: GENE_ASSOCIATION: ( YKL146W or YNL101W ) PROTEIN_ASSOCIATION: ( Avt3-v ) or ( Avt4-v ) SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
reactant: 440272
name: R_L_tyrosine_transport_out_via_proton_symport__vacuolar
reversible: false
kinetic law: 440308
product: 440296
product: 440284
reactant: 440260
fast: false

440272
type: SpeciesReference
stoichiometry: 1.0
species: 286426

286426
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_L_Tyrosine_C9H11NO3

303729
type: LocalParameter
value: 0.0

303728
type: LocalParameter
value: 0.0

303726
type: LocalParameter
value: 0.0

303725
type: LocalParameter
value: 999999.0

303723
type: LocalParameter
value: 0.0

440296
type: SpeciesReference
stoichiometry: 1.0
species: 286417

440284
type: SpeciesReference
stoichiometry: 1.0
species: 284787

440260
type: SpeciesReference
stoichiometry: 1.0
species: 284805

288692
type: Reaction
kinetic law: 376882
product: 376870
reactant: 376858
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Glycine_exchange

296466
type: LocalParameter
value: -0.013661

296464
type: LocalParameter
value: 0.0

296463
type: LocalParameter
value: 0.0

296462
type: LocalParameter
value: 999999.0

296460
type: LocalParameter
value: 0.0

376870
type: SpeciesReference
stoichiometry: 1.0
species: 286777

286777
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Glycine_C2H5NO2

376858
type: SpeciesReference
stoichiometry: 1.0
species: 284660

284660
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Glycine_C2H5NO2

289550
type: Reaction
product: 400844
kinetic law: 400880
notes: GENE_ASSOCIATION: YIL094C PROTEIN_ASSOCIATION: Lys12-m SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 1.1.1.155
reactant: 400832
product: 400856
fast: false
name: R_homoisocitrate_dehydrogenase
reactant: 400820
reversible: true
product: 400868

400844
type: SpeciesReference
stoichiometry: 1.0
species: 284796

299145
type: LocalParameter
value: 0.0

299143
type: LocalParameter
value: 0.082387

299142
type: LocalParameter
value: 0.0

299140
type: LocalParameter
value: 999999.0

299139
type: LocalParameter
value: -999999.0

400832
type: SpeciesReference
stoichiometry: 1.0
species: 285399

400856
type: SpeciesReference
stoichiometry: 1.0
species: 285412

400820
type: SpeciesReference
stoichiometry: 1.0
species: 284894

400868
type: SpeciesReference
stoichiometry: 1.0
species: 285610

285610
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Oxaloglutarate_C7H5O7

287779
type: Reaction
fast: false
product: 358900
reactant: 358888
product: 358912
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
name: R_aspartate_mitochondrial_transport_via_proton_symport
reactant: 358876
kinetic law: 358924
reversible: true

358900
type: SpeciesReference
stoichiometry: 1.0
species: 283806

283806
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Aspartate_C4H6NO4

358888
type: SpeciesReference
stoichiometry: 1.0
species: 284787

358912
type: SpeciesReference
stoichiometry: 1.0
species: 284796

358876
type: SpeciesReference
stoichiometry: 1.0
species: 283800

293091
type: LocalParameter
value: 0.0

293089
type: LocalParameter
value: 0.006097

293087
type: LocalParameter
value: 0.0

293085
type: LocalParameter
value: 999999.0

293083
type: LocalParameter
value: -999999.0

286363
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_tRNA_Tyr__R

284639
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_gamma_L_Glutamyl_L_cysteine_C8H13N2O5S

288677
type: Reaction
kinetic law: 376698
product: 376686
reactant: 376674
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Glycolaldehyde_exchange

296426
type: LocalParameter
value: 0.0

296424
type: LocalParameter
value: 0.0

296423
type: LocalParameter
value: 0.0

296422
type: LocalParameter
value: 999999.0

296420
type: LocalParameter
value: 0.0

376686
type: SpeciesReference
stoichiometry: 1.0
species: 286762

286762
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Glycolaldehyde_C2H4O2

376674
type: SpeciesReference
stoichiometry: 1.0
species: 284556

284556
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Glycolaldehyde_C2H4O2

288881
type: Reaction
kinetic law: 379181
product: 379169
reactant: 379157
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Serine_exchange

296970
type: LocalParameter
value: -0.018214

296968
type: LocalParameter
value: 0.0

296967
type: LocalParameter
value: 0.0

296966
type: LocalParameter
value: 999999.0

296964
type: LocalParameter
value: 0.0

379169
type: SpeciesReference
stoichiometry: 1.0
species: 286966

286966
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Serine_C3H7NO3

379157
type: SpeciesReference
stoichiometry: 1.0
species: 286033

286033
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Serine_C3H7NO3

288127
type: Reaction
fast: false
notes: GENE_ASSOCIATION: YNL247W PROTEIN_ASSOCIATION: Cyt1 SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.16
reactant: 366742
product: 366780
reactant: 366718
name: R_Cysteinyl_tRNA_synthetase
reactant: 366730
reversible: false
product: 366767
product: 366755
kinetic law: 366792

366742
type: SpeciesReference
stoichiometry: 1.0
species: 286291

286291
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_tRNA_Cys__R

366780
type: SpeciesReference
stoichiometry: 1.0
species: 285796

366718
type: SpeciesReference
stoichiometry: 1.0
species: 283830

366730
type: SpeciesReference
stoichiometry: 1.0
species: 284058

366767
type: SpeciesReference
stoichiometry: 1.0
species: 284070

284070
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Cysteinyl_tRNA_Cys__C3H6NOSR

366755
type: SpeciesReference
stoichiometry: 1.0
species: 283713

294314
type: LocalParameter
value: -0.085528

294311
type: LocalParameter
value: 0.0

294308
type: LocalParameter
value: 0.0

294305
type: LocalParameter
value: 999999.0

294302
type: LocalParameter
value: 0.0

284598
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Glutamine_C5H10N2O3

290476
type: Reaction
kinetic law: 430795
fast: false
reactant: 430759
product: 430783
name: R_riboflavin_transport_in_via_proton_symport
reversible: false
reactant: 430747
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
product: 430771

302718
type: LocalParameter
value: 0.0

302716
type: LocalParameter
value: 0.0

302715
type: LocalParameter
value: 0.0

302713
type: LocalParameter
value: 999999.0

302712
type: LocalParameter
value: 0.0

430759
type: SpeciesReference
stoichiometry: 1.0
species: 285988

430783
type: SpeciesReference
stoichiometry: 1.0
species: 285985

430747
type: SpeciesReference
stoichiometry: 1.0
species: 284790

430771
type: SpeciesReference
stoichiometry: 1.0
species: 284787

286645
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Arginine_C6H15N4O2

288331
type: Reaction
kinetic law: 371167
product: 371143
fast: false
reactant: 371130
name: R_2_dehydropantoate_2_reductase
reversible: false
reactant: 371106
product: 371155
reactant: 371118
notes: GENE_ASSOCIATION: YHR063C PROTEIN_ASSOCIATION: Pan5 SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 1.1.1.169

295198
type: LocalParameter
value: -0.015839

295195
type: LocalParameter
value: 0.0

295192
type: LocalParameter
value: 0.0

295189
type: LocalParameter
value: 999999.0

295186
type: LocalParameter
value: 0.0

371143
type: SpeciesReference
stoichiometry: 1.0
species: 285421

371130
type: SpeciesReference
stoichiometry: 1.0
species: 285436

371106
type: SpeciesReference
stoichiometry: 1.0
species: 282993

282993
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Dehydropantoate_C6H9O4

371155
type: SpeciesReference
stoichiometry: 1.0
species: 285649

371118
type: SpeciesReference
stoichiometry: 1.0
species: 284787

286684
type: Species
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_7_8_Diaminononanoate_C9H21N2O2

285868
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888

284781
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Hydrogen_sulfide_H2S

290298
type: Reaction
product: 425100
product: 425088
kinetic law: 425124
reactant: 425064
product: 425112
reactant: 425076
reversible: false
notes: GENE_ASSOCIATION: YMR020W PROTEIN_ASSOCIATION: Fms1 SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 1.5.3.11
reactant: 425052
fast: false
name: R_poylamine_oxidase

425100
type: SpeciesReference
stoichiometry: 1.0
species: 283737

425088
type: SpeciesReference
stoichiometry: 1.0
species: 283443

302095
type: LocalParameter
value: -0.172343

302093
type: LocalParameter
value: 0.0

302092
type: LocalParameter
value: 0.0

302090
type: LocalParameter
value: 999999.0

302089
type: LocalParameter
value: 0.0

425064
type: SpeciesReference
stoichiometry: 1.0
species: 284757

425112
type: SpeciesReference
stoichiometry: 1.0
species: 284747

425076
type: SpeciesReference
stoichiometry: 1.0
species: 285487

425052
type: SpeciesReference
stoichiometry: 1.0
species: 283446

283446
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N1_Acetylspermine_C12H31N4O

284427
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Fe2_Fe

289215
type: Reaction
product: 390155
reversible: false
product: 390143
reactant: 390119
reactant: 390131
name: R_farnesyltranstransferase
notes: GENE_ASSOCIATION: YPL069C PROTEIN_ASSOCIATION: Bts1 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS: 2.5.1.29
kinetic law: 390167
fast: false

390155
type: SpeciesReference
stoichiometry: 1.0
species: 285796

390143
type: SpeciesReference
stoichiometry: 1.0
species: 284580

390119
type: SpeciesReference
stoichiometry: 1.0
species: 284481

390131
type: SpeciesReference
stoichiometry: 1.0
species: 285083

298025
type: LocalParameter
value: 0.0

298024
type: LocalParameter
value: 0.0

298022
type: LocalParameter
value: 0.0

298021
type: LocalParameter
value: 999999.0

298019
type: LocalParameter
value: 0.0

288283
type: Reaction
kinetic law: 370080
product: 370068
product: 370056
reactant: 370044
notes: GENE_ASSOCIATION: YDR127W PROTEIN_ASSOCIATION: Aro1 SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.1.10
fast: false
reversible: false
name: R_3_dehydroquinate_dehydratase__irreversible

294990
type: LocalParameter
value: 0.0

294987
type: LocalParameter
value: 0.076083

294984
type: LocalParameter
value: 0.0

294981
type: LocalParameter
value: 999999.0

294978
type: LocalParameter
value: 0.0

370068
type: SpeciesReference
stoichiometry: 1.0
species: 284757

370056
type: SpeciesReference
stoichiometry: 1.0
species: 283149

370044
type: SpeciesReference
stoichiometry: 1.0
species: 283146

283146
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3_Dehydroquinate_C7H9O6

290626
type: Reaction
fast: false
product: 435803
notes: GENE_ASSOCIATION: YLL057C PROTEIN_ASSOCIATION: Jlp1 SUBSYSTEM: S_Taurine_Metabolism PROTEIN_CLASS: 1.14.11.17
reactant: 435755
product: 435791
reversible: false
name: R_Taurine_dioxygenase
kinetic law: 435827
product: 435779
reactant: 435743
product: 435815
product: 435767
reactant: 435730

435803
type: SpeciesReference
stoichiometry: 1.0
species: 286051

286051
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Sulfite_O3S

435755
type: SpeciesReference
stoichiometry: 1.0
species: 286135

286135
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Taurine_C2H7NO3S

435791
type: SpeciesReference
stoichiometry: 1.0
species: 284787

303253
type: LocalParameter
value: -0.015047

303251
type: LocalParameter
value: 0.0

303250
type: LocalParameter
value: 0.0

303248
type: LocalParameter
value: 999999.0

303247
type: LocalParameter
value: 0.0

435779
type: SpeciesReference
stoichiometry: 1.0
species: 283992

435743
type: SpeciesReference
stoichiometry: 1.0
species: 285487

435815
type: SpeciesReference
stoichiometry: 1.0
species: 286105

435767
type: SpeciesReference
stoichiometry: 1.0
species: 283473

283473
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Aminoacetaldehyde_C2H6NO

435730
type: SpeciesReference
stoichiometry: 1.0
species: 283641

289698
type: Reaction
kinetic law: 405460
product: 405448
reactant: 405436
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_Isopentenyl_diphosphate_transport__mitochondrial

299664
type: LocalParameter
value: 0.0

299662
type: LocalParameter
value: 0.0

299661
type: LocalParameter
value: 0.0

299659
type: LocalParameter
value: 999999.0

299658
type: LocalParameter
value: -999999.0

405448
type: SpeciesReference
stoichiometry: 1.0
species: 285086

285086
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Isopentenyl_diphosphate_C5H9O7P2

405436
type: SpeciesReference
stoichiometry: 1.0
species: 285083

287680
type: Reaction
reactant: 356643
reversible: true
product: 356667
fast: false
name: R_D_arabinono_1_4_lactone_oxidase
product: 356655
notes: GENE_ASSOCIATION: YML086C PROTEIN_ASSOCIATION: Alo1-m SUBSYSTEM: S_Arabinose_Metabolism PROTEIN_CLASS:
reactant: 356631
kinetic law: 356679

356643
type: SpeciesReference
stoichiometry: 1.0
species: 285487

356667
type: SpeciesReference
stoichiometry: 1.0
species: 284747

356655
type: SpeciesReference
stoichiometry: 1.0
species: 284376

284376
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_erythro_Ascorbate_C5H6O5

356631
type: SpeciesReference
stoichiometry: 1.0
species: 283422

283422
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Arabinono_1_4_lactone_C5H8O5

292793
type: LocalParameter
value: 0.0

292791
type: LocalParameter
value: 0.0

292789
type: LocalParameter
value: 0.0

292787
type: LocalParameter
value: 999999.0

292785
type: LocalParameter
value: -999999.0

288322
type: Reaction
reactant: 370912
product: 370948
product: 370936
product: 370924
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 2.7.1.24
reactant: 370900
name: R_dephospho_CoA_kinase__mitochondrial
reversible: false
fast: false
kinetic law: 370961

370912
type: SpeciesReference
stoichiometry: 1.0
species: 284271

370948
type: SpeciesReference
stoichiometry: 1.0
species: 284796

370936
type: SpeciesReference
stoichiometry: 1.0
species: 284016

370924
type: SpeciesReference
stoichiometry: 1.0
species: 283608

370900
type: SpeciesReference
stoichiometry: 1.0
species: 283836

295159
type: LocalParameter
value: 0.0

295156
type: LocalParameter
value: 0.0

295153
type: LocalParameter
value: 0.0

295150
type: LocalParameter
value: 999999.0

295147
type: LocalParameter
value: 0.0

289299
type: Reaction
reactant: 392921
reactant: 393017
name: R_glycerol_3_phosphate_acyltransferase__glycerone_phosphate___yeast_specific
fast: false
reactant: 392957
kinetic law: 393053
reactant: 393005
reactant: 392981
reactant: 392969
reactant: 392933
reactant: 392993
reactant: 392945
product: 393041
reversible: false
product: 393029
notes: GENE_ASSOCIATION: ( YKR067W or YBL011W ) PROTEIN_ASSOCIATION: ( Gpt2 ) or ( Sct1 ) SUBSYSTEM: S_Phospholipid_Biosynthesis PROTEIN_CLASS:

392921
type: SpeciesReference
stoichiometry: 0.02
species: 284124

393017
type: SpeciesReference
stoichiometry: 0.1
species: 286150

392957
type: SpeciesReference
stoichiometry: 0.17
species: 284846

298298
type: LocalParameter
value: -0.004158

298297
type: LocalParameter
value: 0.0

298295
type: LocalParameter
value: 0.0

298294
type: LocalParameter
value: 999999.0

298293
type: LocalParameter
value: 0.0

393005
type: SpeciesReference
stoichiometry: 0.05
species: 286099

392981
type: SpeciesReference
stoichiometry: 0.24
species: 285577

392969
type: SpeciesReference
stoichiometry: 0.09
species: 285556

392933
type: SpeciesReference
stoichiometry: 0.06
species: 284169

392993
type: SpeciesReference
stoichiometry: 0.27
species: 285775

392945
type: SpeciesReference
stoichiometry: 1.0
species: 284196

393041
type: SpeciesReference
stoichiometry: 1.0
species: 284013

393029
type: SpeciesReference
stoichiometry: 0.01
species: 282920

282920
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871

287494
type: Reaction
kinetic law: 352502
fast: false
reactant: 352454
name: R_O_acetylhomoserine__thiol__lyase
reversible: false
reactant: 352442
product: 352466
product: 352478
notes: GENE_ASSOCIATION: YLR303W PROTEIN_ASSOCIATION: Met17 SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 4.2.99.8
product: 352490

292225
type: LocalParameter
value: 0.0

292223
type: LocalParameter
value: 0.016495

292221
type: LocalParameter
value: 0.0

292219
type: LocalParameter
value: 999999.0

292217
type: LocalParameter
value: 0.0

352454
type: SpeciesReference
stoichiometry: 1.0
species: 284781

352442
type: SpeciesReference
stoichiometry: 1.0
species: 283554

352466
type: SpeciesReference
stoichiometry: 1.0
species: 283497

352478
type: SpeciesReference
stoichiometry: 1.0
species: 284787

352490
type: SpeciesReference
stoichiometry: 1.0
species: 284824

287959
type: Reaction
product: 363072
kinetic law: 363096
notes: GENE_ASSOCIATION: ( YHL003C or YKL008C or YBR183W ) PROTEIN_ASSOCIATION: ( Lag1 ) or ( Lac1 ) or ( Ypc1 ) SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
product: 363060
reactant: 363048
reactant: 363036
product: 363084
name: R_Ceramide_2_synthase__24C___endoplasmic_reticular
reversible: false
fast: false

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stoichiometry: 1.0
species: 284022

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value: 0.0

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value: 0.0

293655
type: LocalParameter
value: 0.0

293653
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value: 999999.0

293650
type: LocalParameter
value: 0.0

363060
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stoichiometry: 1.0
species: 283917

283917
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Ceramide_2__Phytosphingosinen_C240__C42H85NO4

363048
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stoichiometry: 1.0
species: 286396

286396
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873

363036
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stoichiometry: 1.0
species: 285886

363084
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stoichiometry: 1.0
species: 284802

286435
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Tyrosyl_tRNA_Tyr__C9H10NO2R

285811
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Diphosphoinositol_tetrakisphosphate_C6H7O24P6

289626
type: Reaction
kinetic law: 403295
product: 403283
product: 403271
reactant: 403258
notes: GENE_ASSOCIATION: YER065C PROTEIN_ASSOCIATION: Icl1 SUBSYSTEM: S_Anaplerotic_reactions PROTEIN_CLASS: 4.1.3.1
fast: false
reversible: false
name: R_Isocitrate_lyase

299409
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value: 0.0

299407
type: LocalParameter
value: 0.015001

299406
type: LocalParameter
value: 0.0

299404
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value: 999999.0

299403
type: LocalParameter
value: 0.0

403283
type: SpeciesReference
stoichiometry: 1.0
species: 286105

403271
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stoichiometry: 1.0
species: 284648

403258
type: SpeciesReference
stoichiometry: 1.0
species: 284984

289467
type: Reaction
product: 398493
fast: false
product: 398481
notes: GENE_ASSOCIATION: YER005W PROTEIN_ASSOCIATION: Ynd1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.6.1.5
reversible: false
reactant: 398469
name: R_GTP_diphosphohydrolase
product: 398505
reactant: 398457
kinetic law: 398517

398493
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stoichiometry: 2.0
species: 284787

398481
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stoichiometry: 1.0
species: 284690

398469
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stoichiometry: 2.0
species: 284757

398505
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stoichiometry: 2.0
species: 285751

398457
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stoichiometry: 1.0
species: 284732

298870
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value: -0.023758

298868
type: LocalParameter
value: 0.0

298867
type: LocalParameter
value: 0.0

298865
type: LocalParameter
value: 999999.0

298864
type: LocalParameter
value: 0.0

289463
type: Reaction
product: 398348
kinetic law: 398360
name: R_GTP_cyclohydrolase_I
notes: GENE_ASSOCIATION: YGR267C PROTEIN_ASSOCIATION: Fol2 SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 3.5.4.16
reversible: false
fast: false
reactant: 398311
product: 398324
product: 398336
reactant: 398299

398348
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stoichiometry: 1.0
species: 284787

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value: 0.0

298854
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value: 0.0

298853
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value: 0.0

298851
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value: 999999.0

298850
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value: 0.0

398311
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stoichiometry: 1.0
species: 284757

398324
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stoichiometry: 1.0
species: 283632

398336
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stoichiometry: 1.0
species: 284466

398299
type: SpeciesReference
stoichiometry: 1.0
species: 284732

285727
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Phenethyl_acetate_C10H12O2

290526
type: Reaction
product: 432500
product: 432487
fast: false
kinetic law: 432512
reactant: 432451
notes: GENE_ASSOCIATION: YJR159W PROTEIN_ASSOCIATION: Sor1 SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.14
reactant: 432463
name: R_L_sorbitol_dehydrogenase__L_sorbose_producing_
product: 432475
reversible: false

432500
type: SpeciesReference
stoichiometry: 1.0
species: 286093

286093
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Sorbose_C6H12O6

432487
type: SpeciesReference
stoichiometry: 1.0
species: 285409

302893
type: LocalParameter
value: -0.002178

302891
type: LocalParameter
value: 0.0

302890
type: LocalParameter
value: 0.0

302888
type: LocalParameter
value: 999999.0

302887
type: LocalParameter
value: 0.0

432451
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stoichiometry: 1.0
species: 285396

432463
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stoichiometry: 1.0
species: 286018

432475
type: SpeciesReference
stoichiometry: 1.0
species: 284787

284852
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885

287851
type: Reaction
notes: GENE_ASSOCIATION: YGR286C PROTEIN_ASSOCIATION: Bio2 SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 2.8.1.6
fast: false
product: 360574
kinetic law: 360587
reversible: true
product: 360562
reactant: 360550
name: R_biotin_synthase
reactant: 360538

360574
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stoichiometry: 2.0
species: 284787

293309
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value: 0.0

293307
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value: 0.0

293305
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value: 0.0