MODEL1012110001
type: SBMLModel
name: function_4_pyruvate kinase
species: COPASI8
function def: 170110
compartment: COPASI2
species: COPASI16
species: COPASI19
name: function_4_phosphoglycerate mutase
species: COPASI30
reaction: COPASI43
species: COPASI26
function def: 170116
name: function_4_phosphofructokinase
species: COPASI29
name: function_4_hexokinase (D-glucose:ATP)
reaction: COPASI37
function def: 170101
reaction: COPASI42
reaction: COPASI35
volume units: volume
function def: 170122
species: COPASI33
species: COPASI12
function def: 170119
species: COPASI21
reaction: COPASI38
species: COPASI15
name: function_4_glyceraldehyde-3-phosphate dehydrogenase
species: COPASI7
species: COPASI25
reaction: COPASI44
compartment: COPASI3
area units: area
species: COPASI18
is described by: http://identifiers.org/pubmed/21114840
species: COPASI10
species: COPASI32
species: COPASI28
function def: 170097
name: function_4_phosphoglycerate kinase
species: COPASI20
species: COPASI23
species: COPASI6
reaction: COPASI39
length unit: length
species: COPASI11
name: function_4_fructose-bisphosphate aldolase
function def: 170104
species: COPASI14
function def: 170113
function def: 170107
species: COPASI17
time units: time
name: function_4_enolase
compartment: COPASI4
species: COPASI24
species: COPASI9
name: function_4_pyruvate decarboxylase
name: Li2010_YeastGlycolysis
species: COPASI27
name: function_4_glucose-6-phosphate isomerase
curated: false
reaction: COPASI40
substance units: substance
notes: This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer toCC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. . To cite BioModels Database, please use:Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
species: COPASI31
function def: 170098
species: COPASI34
reaction: COPASI36
reaction: COPASI41
species: COPASI13
species: COPASI22
species: COPASI5

COPASI8
type: Species
is: CHEBI:15954
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: D-Glucose 6-phosphate

COPASI2
type: Compartment
is: GO:0005737
constant: true
size: 1.0
spatial dimensions: 3.0
name: Cytoplasm

COPASI16
type: Species
is: CHEBI:17794
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 3-Phospho-D-glycerate

COPASI19
type: Species
is: CHEBI:15361
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Pyruvate

COPASI30
type: Species
initial amount: NaN
is: P00360
name: YJL052W
boundary condition: false
is: S000003588
has only substance units: false
constant: false
initial concentration: 0.03453452445155
in compartment: COPASI2

COPASI43
type: Reaction
is described by: http://identifiers.org/ec-code/2.7.1.40
reversible: true
is described by: http://identifiers.org/pubmed/6185493
product: 988195
reactant: 988147
modifier: 988207
reactant: 988159
fast: false
name: pyruvate kinase
kinetic law: 988219
product: 988183
reactant: 988171

988195
type: SpeciesReference
stoichiometry: 1.0
species: COPASI19

988147
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

COPASI10
type: Species
is: CHEBI:16761
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: ADP

COPASI33
type: Species
initial concentration: 0.29788672074056
constant: false
initial amount: NaN
is: P00549
in compartment: COPASI2
name: YAL038W
has only substance units: false
is: S000000036
boundary condition: false

988159
type: SpeciesReference
stoichiometry: 1.0
species: COPASI17

COPASI17
type: Species
is: CHEBI:15378
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.0
initial amount: NaN
in compartment: COPASI2
name: H+

170093
type: LocalParameter
value: 1.0
name: k4

988183
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

COPASI6
type: Species
is: CHEBI:15422
constant: false
boundary condition: false
has only substance units: false
initial concentration: 3.5
initial amount: NaN
in compartment: COPASI2
name: ATP

988171
type: SpeciesReference
stoichiometry: 1.0
species: COPASI18

COPASI18
type: Species
is: CHEBI:18021
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Phosphoenolpyruvate

COPASI26
type: Species
constant: false
boundary condition: false
is: P16861
name: YGR240C:YMR205C
initial amount: NaN
initial concentration: 0.00337856838203
in compartment: COPASI2
has only substance units: false
is: P16862

COPASI29
type: Species
is: S000003486
in compartment: COPASI2
boundary condition: false
is: P00924
name: YGR254W
constant: false
initial amount: NaN
initial concentration: 0.09259970021451
has only substance units: false

COPASI37
type: Reaction
reactant: 987738
is described by: http://identifiers.org/ec-code/5.3.1.9
product: 987750
reversible: true
is described by: http://identifiers.org/pubmed/8435847
kinetic law: 987774
fast: false
modifier: 987762
name: glucose-6-phosphate isomerase

987738
type: SpeciesReference
stoichiometry: 1.0
species: COPASI8

987750
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

COPASI7
type: Species
is: CHEBI:15946
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: D-Fructose 6-phosphate

170081
type: LocalParameter
value: 0.0
name: Vmax

170078
type: LocalParameter
value: 0.86
name: Km

170075
type: LocalParameter
value: 1.9
name: Ki

170074
type: LocalParameter
value: 0.0
name: I

COPASI27
type: Species
in compartment: COPASI2
constant: false
is: S000000400
initial amount: NaN
name: YBR196C
has only substance units: false
initial concentration: 0.01103966864816
is: P12709
boundary condition: false

COPASI42
type: Reaction
is described by: http://identifiers.org/ec-code/5.4.2.1
modifier: 988123
kinetic law: 988135
reactant: 988099
is described by: http://identifiers.org/pubmed/3033435
product: 988111
name: phosphoglycerate mutase
reversible: true
fast: false

COPASI32
type: Species
name: YKL152C
initial concentration: 0.06322939301798
is: P00950
constant: false
boundary condition: false
is: S000001635
initial amount: NaN
has only substance units: false
in compartment: COPASI2

170092
type: LocalParameter
value: 1.0
name: k3

988099
type: SpeciesReference
stoichiometry: 1.0
species: COPASI16

988111
type: SpeciesReference
stoichiometry: 1.0
species: COPASI11

COPASI11
type: Species
is: CHEBI:17835
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: D-Glycerate 2-phosphate

COPASI35
type: Reaction
is described by: http://identifiers.org/ec-code/4.1.2.13
kinetic law: 987642
is described by: http://identifiers.org/pubmed/8435847
reversible: true
product: 987606
fast: false
modifier: 987630
reactant: 987594
name: fructose-bisphosphate aldolase
product: 987618

170072
type: LocalParameter
value: 4.13856
name: kcat

170069
type: LocalParameter
value: 0.450701
name: Ks

170068
type: LocalParameter
value: 4.0625E-5
name: Et

987606
type: SpeciesReference
stoichiometry: 1.0
species: COPASI20

COPASI20
type: Species
is: CHEBI:16108
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Dihydroxyacetone phosphate

COPASI25
type: Species
boundary condition: false
constant: false
is: P14540
initial concentration: 0.18915046668062
name: YKL060C
is: S000001543
initial amount: NaN
in compartment: COPASI2
has only substance units: false

987594
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

COPASI5
type: Species
is: CHEBI:16905
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: D-Fructose 1,6-bisphosphate

987618
type: SpeciesReference
stoichiometry: 1.0
species: COPASI12

COPASI12
type: Species
is: CHEBI:29052
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Glyceraldehyde 3-phosphate

COPASI21
type: Species
is: CHEBI:15377
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: H2O

COPASI38
type: Reaction
name: phosphoglycerate kinase
is described by: http://identifiers.org/ec-code/2.7.2.3
reactant: 987786
is described by: http://identifiers.org/pubmed/6347186
modifier: 987834
reactant: 987798
reversible: true
product: 987810
kinetic law: 987846
fast: false
product: 987822

987786
type: SpeciesReference
stoichiometry: 1.0
species: COPASI9

COPASI9
type: Species
is: CHEBI:16001
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 3-Phospho-D-glyceroyl phosphate

COPASI28
type: Species
name: YCR012W
is: P00560
boundary condition: false
constant: false
initial amount: NaN
has only substance units: false
is: S000000605
in compartment: COPASI2
initial concentration: 0.05511025068489

987798
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

987810
type: SpeciesReference
stoichiometry: 1.0
species: COPASI16

170085
type: LocalParameter
value: 343.5
name: kcat

170082
type: LocalParameter
value: 0.77
name: Km

987822
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

COPASI15
type: Species
is: CHEBI:17634
constant: false
boundary condition: false
has only substance units: false
initial concentration: 50.0
initial amount: NaN
in compartment: COPASI2
name: D-Glucose

COPASI44
type: Reaction
name: pyruvate decarboxylase
modifier: 988279
kinetic law: 988291
is described by: http://identifiers.org/ec-code/4.1.1.1
product: 988267
fast: false
reversible: true
reactant: 988231
product: 988255
reactant: 988243

COPASI34
type: Species
has only substance units: false
is: P06169
initial concentration: 0.09520868848003
boundary condition: false
constant: false
name: YLR044C
in compartment: COPASI2
initial amount: NaN
is: S000004034

170094
type: LocalParameter
value: 1.0
name: k5

988267
type: SpeciesReference
stoichiometry: 1.0
species: COPASI24

COPASI24
type: Species
is: CHEBI:16526
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: CO2

988231
type: SpeciesReference
stoichiometry: 1.0
species: COPASI17

988255
type: SpeciesReference
stoichiometry: 1.0
species: COPASI23

COPASI23
type: Species
is: CHEBI:15343
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Acetaldehyde

988243
type: SpeciesReference
stoichiometry: 1.0
species: COPASI19

COPASI3
type: Compartment
is: GO:0005886
constant: true
size: 1.0
spatial dimensions: 3.0
name: Plasma membrane

COPASI39
type: Reaction
fast: false
product: 987870
is described by: http://identifiers.org/ec-code/4.2.1.11
reversible: true
is described by: http://identifiers.org/pubmed/7520111
reactant: 987858
modifier: 987894
kinetic law: 987906
product: 987882
name: enolase

987870
type: SpeciesReference
stoichiometry: 1.0
species: COPASI21

987858
type: SpeciesReference
stoichiometry: 1.0
species: COPASI11

170089
type: LocalParameter
value: 42.0
name: Vmax

170086
type: LocalParameter
value: 48.0
name: Km

987882
type: SpeciesReference
stoichiometry: 1.0
species: COPASI18

COPASI14
type: Species
is: CHEBI:18367
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.0
initial amount: NaN
in compartment: COPASI2
name: Phosphate

COPASI4
type: Compartment
is: GO:0005576
constant: true
size: 1.0
spatial dimensions: 3.0
name: Extracellular

COPASI40
type: Reaction
reversible: true
reactant: 987918
product: 987954
name: glyceraldehyde-3-phosphate dehydrogenase
modifier: 987991
fast: false
reactant: 987942
reactant: 987930
kinetic law: 988003
product: 987966
product: 987979
is described by: http://identifiers.org/ec-code/1.2.1.12
is described by: http://identifiers.org/pubmed/3905788

987918
type: SpeciesReference
stoichiometry: 1.0
species: COPASI12

987954
type: SpeciesReference
stoichiometry: 1.0
species: COPASI9

987942
type: SpeciesReference
stoichiometry: 1.0
species: COPASI14

987930
type: SpeciesReference
stoichiometry: 1.0
species: COPASI13

COPASI13
type: Species
is: CHEBI:15846
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.0
initial amount: NaN
in compartment: COPASI2
name: Nicotinamide adenine dinucleotide

170090
type: LocalParameter
value: 1.0
name: k1

987966
type: SpeciesReference
stoichiometry: 1.0
species: COPASI17

987979
type: SpeciesReference
stoichiometry: 1.0
species: COPASI22

COPASI22
type: Species
is: CHEBI:16908
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Nicotinamide adenine dinucleotide - reduced

COPASI31
type: Species
is: P04806
is: S000001949
constant: false
has only substance units: false
in compartment: COPASI2
initial amount: NaN
boundary condition: false
initial concentration: 0.00166468793545
name: YFR053C

COPASI36
type: Reaction
modifier: 987714
reactant: 987654
fast: false
is described by: http://identifiers.org/ec-code/2.7.1.11
kinetic law: 987726
product: 987702
name: phosphofructokinase
reactant: 987666
product: 987690
reversible: true
is described by: http://identifiers.org/pubmed/3007939
product: 987678

987654
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

170073
type: LocalParameter
value: 1.0
name: k0

987702
type: SpeciesReference
stoichiometry: 1.0
species: COPASI17

987666
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

987690
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

987678
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

COPASI41
type: Reaction
reversible: true
is described by: http://identifiers.org/ec-code/2.7.1.1
modifier: 988075
fast: false
is described by: http://identifiers.org/pubmed/6394965
product: 988063
name: hexokinase (D-glucose:ATP)
kinetic law: 988087
product: 988051
reactant: 988015
product: 988039
reactant: 988027

988063
type: SpeciesReference
stoichiometry: 1.0
species: COPASI17

170091
type: LocalParameter
value: 1.0
name: k2

988051
type: SpeciesReference
stoichiometry: 1.0
species: COPASI8

988015
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

988039
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

988027
type: SpeciesReference
stoichiometry: 1.0
species: COPASI15