MODEL1011080004
type: SBMLModel
reaction: 378969
reaction: 379035
species: 377691
species: 377772
species: 378065
species: 378566
species: 378146
reaction: 379266
species: 378515
reaction: 379596
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species: 378404
species: 377939
reaction: 379812
species: 378482
reaction: 379512
species: 377643
reaction: 379761
reaction: 379776
species: 378296
species: 378089
is described by: http://identifiers.org/pubmed/20957118
reaction: 379581
reaction: 379527
reaction: 379614
reaction: 379620
reaction: 379497
reaction: 379452
species: 377874
species: 377823
reaction: 379755
species: 378248
species: 378443
species: 377978
reaction: 379683
species: 378158
reaction: 379827
species: 377682
species: 377649
reaction: 378780
reaction: 379179
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reaction: 378795
species: 378314
reaction: 378816
species: 377914
reaction: 379458
reaction: 379629
species: 377619
reaction: 379158
species: 377751
reaction: 378774
reaction: 378690
species: 378044
species: 378545
species: 378125
reaction: 378636
reaction: 378924
species: 377951
reaction: 379068
reaction: 378972
species: 378560
species: 378353
species: 377694
reaction: 379314
species: 377721
species: 378068
reaction: 378753
reaction: 378903
reaction: 379215
species: 377559
reaction: 378918
reaction: 379545
reaction: 379389
reaction: 379047
reaction: 379053
species: 378011
species: 378083
reaction: 379329

378969
type: Reaction
name: dehydro-L-gulonatedecarboxylase
reactant: 312485
reactant: 312473
reversible: true
kinetic law: 312521
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Pentose and Glucuronate Interconversions
product: 312497
product: 312509

312485
type: SpeciesReference
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species: 378077

378077
type: Species
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initial concentration: NaN
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name: H+

377545
type: Compartment
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spatial dimensions: 3.0
name: Cytoplasm

312473
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species: 377613

377613
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initial concentration: NaN
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in compartment: 377545
name: 3-Dehydro-L-gulonate

381314
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304615
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multipler: 2.77777777777778E-4
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304603
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381311
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381308
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value: 1000.0

381305
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312497
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species: 377817

377817
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name: CO2

312509
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species: 378560

378560
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name: L-Xylulose

379035
type: Reaction
fast: false
kinetic law: 313935
reversible: false
product: 313911
reactant: 313887
product: 313923
reactant: 313875
notes: GENE_ASSOCIATION: (5297.1) SUBSYSTEM: Inositol Phosphate Metabolism
name: phosphatidylinositol-5-phosphate4-kinase
product: 313899

381534
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value: 0.0

381531
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381528
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381525
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313911
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313887
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species: 378320

378320
type: Species
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initial concentration: NaN
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name: 1-Phosphatidyl-1D-myo-inositol 5-phosphate (Homo sapiens)

313923
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species: 378308

378308
type: Species
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initial concentration: NaN
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name: phosphatidylinositol 4,5-bisphosphate (Homo sapiens)

313875
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species: 377769

377769
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name: ATP

313899
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species: 377700

377700
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initial concentration: NaN
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name: ADP

377691
type: Species
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initial concentration: NaN
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in compartment: 377546
name: Adenine

377546
type: Compartment
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size: 1.0
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name: Extracellular

377772
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initial concentration: NaN
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in compartment: 377549
name: ATP

377549
type: Compartment
constant: true
size: 1.0
spatial dimensions: 3.0
name: Mitochondrion

378065
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initial concentration: NaN
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name: H2O

378566
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initial concentration: NaN
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in compartment: 377546

378146
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
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in compartment: 377545
name: L-Lactate

379266
type: Reaction
product: 318337
reactant: 318300
product: 318324
kinetic law: 318349
reactant: 318312
fast: false
notes: GENE_ASSOCIATION: (11001.1) SUBSYSTEM: Transport, Extracellular
reversible: true
name: fattyacidelectroneutraltransport

318337
type: SpeciesReference
stoichiometry: 1.0
species: 378209

378209
type: Species
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initial concentration: NaN
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in compartment: 377546
name: Sodium

318300
type: SpeciesReference
stoichiometry: 1.0
species: 377844

377844
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: cervonic acid, C22:6 n-3

318324
type: SpeciesReference
stoichiometry: 1.0
species: 377847

377847
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: cervonic acid, C22:6 n-3

382090
type: LocalParameter
units: 304591
value: 0.0

382088
type: LocalParameter
units: 304591
value: 0.0

382086
type: LocalParameter
units: 304591
value: 1000.0

382084
type: LocalParameter
units: 304591
value: -1000.0

318312
type: SpeciesReference
stoichiometry: 1.0
species: 378206

378206
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Sodium

378515
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Tyrosine

379596
type: Reaction
kinetic law: 324382
reactant: 324370
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382875
type: LocalParameter
units: 304591
value: 0.0

382873
type: LocalParameter
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value: 0.0

382871
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units: 304591
value: 13.5135135135135

382869
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units: 304591
value: 0.0

324370
type: SpeciesReference
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species: 378530

378530
type: Species
constant: false
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initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Urea

377972
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-Glutamate 5-phosphate

378404
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Pyruvate

377939
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: GDP

379812
type: Reaction
kinetic law: 326118
reactant: 326106
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Valineexchange

383182
type: LocalParameter
units: 304591
value: 0.0

383181
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value: 0.0

383180
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units: 304591
value: 0.0

383179
type: LocalParameter
units: 304591
value: -1000.0

326106
type: SpeciesReference
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species: 378539

378539
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Valine

378482
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Sphingosine 1-phosphate

377555
type: Compartment
constant: true
size: 1.0
spatial dimensions: 3.0
name: Endoplasmic_reticulum

379512
type: Reaction
reversible: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Inositol Phosphate Metabolism
product: 322697
name: phosphatidylinositol-4-phosphate4-phosphatase,nuclear
kinetic law: 322709
fast: false
reactant: 322672
product: 322685
reactant: 322660

322697
type: SpeciesReference
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species: 378347

378347
type: Species
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initial concentration: NaN
initial amount: NaN
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name: Phosphate

377552
type: Compartment
constant: true
size: 1.0
spatial dimensions: 3.0
name: Nucleus

382679
type: LocalParameter
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value: 0.0

382677
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value: 0.0

382675
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value: 1000.0

382673
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units: 304591
value: 0.0

322672
type: SpeciesReference
stoichiometry: 1.0
species: 378317

378317
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: 1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)

322685
type: SpeciesReference
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species: 378326

378326
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: phosphatidylinositol (homo sapiens)

322660
type: SpeciesReference
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species: 378068

378068
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: H2O

377643
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: R group 6 Coenzyme A homo sapiens

379761
type: Reaction
kinetic law: 325708
reactant: 325696
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Reducedglutathioneexchange

383114
type: LocalParameter
units: 304591
value: 0.0

383113
type: LocalParameter
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value: 0.0

383112
type: LocalParameter
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383111
type: LocalParameter
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value: -1000.0

325696
type: SpeciesReference
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species: 378020

378020
type: Species
constant: false
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has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Reduced glutathione

379776
type: Reaction
kinetic law: 325828
reactant: 325816
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Acetaldehydeexchange

383134
type: LocalParameter
units: 304591
value: 0.0

383133
type: LocalParameter
units: 304591
value: 0.0

383132
type: LocalParameter
units: 304591
value: 13.5135135135135

383131
type: LocalParameter
units: 304591
value: -1000.0

325816
type: SpeciesReference
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species: 377664

377664
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Acetaldehyde

378296
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: 4-oxo-retonoic acid

378089
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: H+

377558
type: Compartment
constant: true
size: 1.0
spatial dimensions: 3.0
name: Peroxisome

379581
type: Reaction
kinetic law: 324261
reactant: 324249
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382840
type: LocalParameter
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value: 0.0

382838
type: LocalParameter
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value: 0.0

382836
type: LocalParameter
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value: 13.5135135135135

382834
type: LocalParameter
units: 304591
value: 0.0

324249
type: SpeciesReference
stoichiometry: 1.0
species: 378512

378512
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Tryptamine

379527
type: Reaction
reversible: false
name: D-Lactaldehyde:NAD+1-oxidoreductase
kinetic law: 322986
fast: false
product: 322973
reactant: 322937
product: 322961
reactant: 322949
notes: GENE_ASSOCIATION: (8574.1) SUBSYSTEM: Pyruvate Metabolism
reactant: 322925

382714
type: LocalParameter
units: 304591
value: 0.0

382712
type: LocalParameter
units: 304591
value: 0.0

382710
type: LocalParameter
units: 304591
value: 1000.0

382708
type: LocalParameter
units: 304591
value: 0.0

322973
type: SpeciesReference
stoichiometry: 1.0
species: 378212

378212
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Nicotinamide adenine dinucleotide

322937
type: SpeciesReference
stoichiometry: 1.0
species: 378200

378200
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Methylglyoxal

322961
type: SpeciesReference
stoichiometry: 1.0
species: 378152

378152
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Lactaldehyde

322949
type: SpeciesReference
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species: 378218

378218
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Nicotinamide adenine dinucleotide - reduced

322925
type: SpeciesReference
stoichiometry: 1.0
species: 378077

379614
type: Reaction
kinetic law: 324526
reactant: 324514
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382915
type: LocalParameter
units: 304591
value: 0.0

382914
type: LocalParameter
units: 304591
value: 0.0

382913
type: LocalParameter
units: 304591
value: 13.5135135135135

382911
type: LocalParameter
units: 304591
value: 0.0

324514
type: SpeciesReference
stoichiometry: 1.0
species: 378506

378506
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Tryptophan

379620
type: Reaction
kinetic law: 324574
reactant: 324562
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382925
type: LocalParameter
units: 304591
value: 0.0

382924
type: LocalParameter
units: 304591
value: 0.0

382923
type: LocalParameter
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value: 13.5135135135135

382922
type: LocalParameter
units: 304591
value: 0.0

324562
type: SpeciesReference
stoichiometry: 1.0
species: 378455

378455
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Serine

379497
type: Reaction
kinetic law: 322480
product: 322468
reactant: 322456
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: ribosetransportviadiffusion

382644
type: LocalParameter
units: 304591
value: 0.0

382642
type: LocalParameter
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value: 0.0

382640
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value: 1000.0

382638
type: LocalParameter
units: 304591
value: -1000.0

322468
type: SpeciesReference
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species: 378434

378434
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Ribose

322456
type: SpeciesReference
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species: 378437

378437
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: D-Ribose

379452
type: Reaction
kinetic law: 321692
product: 321680
reactant: 321668
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: false
name: NADtransporter,peroxisome

382539
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units: 304591
value: 0.0

382537
type: LocalParameter
units: 304591
value: 0.0

382535
type: LocalParameter
units: 304591
value: 1000.0

382534
type: LocalParameter
units: 304591
value: 0.0

321680
type: SpeciesReference
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species: 378218

321668
type: SpeciesReference
stoichiometry: 1.0
species: 378224

378224
type: Species
constant: false
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has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Nicotinamide adenine dinucleotide - reduced

377874
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Dehydroascorbate

377823
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: CO2

379755
type: Reaction
kinetic law: 325660
reactant: 325648
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Calciumexchange

383106
type: LocalParameter
units: 304591
value: 0.0

383105
type: LocalParameter
units: 304591
value: 0.0

383104
type: LocalParameter
units: 304591
value: 0.0

383103
type: LocalParameter
units: 304591
value: -1000.0

325648
type: SpeciesReference
stoichiometry: 1.0
species: 377784

377784
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Calcium

378248
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Ammonium

378443
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Sedoheptulose 7-phosphate

377978
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Glutamate

379683
type: Reaction
kinetic law: 325079
reactant: 325067
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

383010
type: LocalParameter
units: 304591
value: 0.0

383009
type: LocalParameter
units: 304591
value: 0.0

383008
type: LocalParameter
units: 304591
value: 13.5135135135135

383007
type: LocalParameter
units: 304591
value: 0.0

325067
type: SpeciesReference
stoichiometry: 1.0
species: 378338

378338
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Phosphate

378158
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Leucine

379827
type: Reaction
kinetic law: 326238
reactant: 326226
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Phenylalanineexchange

383202
type: LocalParameter
units: 304591
value: 0.0

383201
type: LocalParameter
units: 304591
value: 0.0

383200
type: LocalParameter
units: 304591
value: 0.0

383199
type: LocalParameter
units: 304591
value: -1000.0

326226
type: SpeciesReference
stoichiometry: 1.0
species: 378335

378335
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Phenylalanine

377682
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Acetylcholine

377649
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: R total Coenzyme A

378780
type: Reaction
kinetic law: 308509
product: 308497
reactant: 308485
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: hydrogenperoxideperoxisomaltransportviadiffusion

380684
type: LocalParameter
units: 304591
value: 0.0

380681
type: LocalParameter
units: 304591
value: 0.0

380678
type: LocalParameter
units: 304591
value: 1000.0

380675
type: LocalParameter
units: 304591
value: -1000.0

308497
type: SpeciesReference
stoichiometry: 1.0
species: 378056

378056
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Hydrogen peroxide

308485
type: SpeciesReference
stoichiometry: 1.0
species: 378047

378047
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Hydrogen peroxide

379179
type: Reaction
product: 316767
product: 316755
reversible: true
reactant: 316743
notes: GENE_ASSOCIATION: (6540.1) SUBSYSTEM: Transport, Extracellular
kinetic law: 316779
fast: false
reactant: 316731

316767
type: SpeciesReference
stoichiometry: 2.0
species: 378206

316755
type: SpeciesReference
stoichiometry: 1.0
species: 377619

377619
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 4-Aminobutanoate

316743
type: SpeciesReference
stoichiometry: 2.0
species: 378209

381887
type: LocalParameter
units: 304591
value: 0.0

381885
type: LocalParameter
units: 304591
value: 0.0

381883
type: LocalParameter
units: 304591
value: 1000.0

381881
type: LocalParameter
units: 304591
value: -1000.0

316731
type: SpeciesReference
stoichiometry: 1.0
species: 377622

377622
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: 4-Aminobutanoate

378263
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: nervonic acid

378795
type: Reaction
kinetic law: 308763
reversible: false
reactant: 308727
notes: GENE_ASSOCIATION: (51.1) or (51.2) SUBSYSTEM: Fatty Acid Metabolism
product: 308751
fast: false
product: 308739
name: acyl-CoAoxidase(hexadecanoyl-CoA),peroxisomal
reactant: 308715

380734
type: LocalParameter
units: 304591
value: 0.0

380731
type: LocalParameter
units: 304591
value: 0.0

380728
type: LocalParameter
units: 304591
value: 1000.0

380725
type: LocalParameter
units: 304591
value: 0.0

308727
type: SpeciesReference
stoichiometry: 1.0
species: 378356

378356
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Palmitoyl-CoA (n-C16:0CoA)

308751
type: SpeciesReference
stoichiometry: 1.0
species: 378101

378101
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: trans-Hexadec-2-enoyl-CoA

308739
type: SpeciesReference
stoichiometry: 1.0
species: 378056

308715
type: SpeciesReference
stoichiometry: 1.0
species: 378278

378278
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: O2

378314
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)

378816
type: Reaction
kinetic law: 309162
product: 309150
reactant: 309138
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: H2Oendoplasmicreticulumtransport

380804
type: LocalParameter
units: 304591
value: 0.0

380801
type: LocalParameter
units: 304591
value: 0.0

380798
type: LocalParameter
units: 304591
value: 1000.0

380795
type: LocalParameter
units: 304591
value: -1000.0

309150
type: SpeciesReference
stoichiometry: 1.0
species: 378071

378071
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: H2O

309138
type: SpeciesReference
stoichiometry: 1.0
species: 378059

378059
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: H2O

377914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Fructose 1,6-bisphosphate

379458
type: Reaction
notes: GENE_ASSOCIATION: (5743.1) SUBSYSTEM: Eicosanoid Metabolism
name: ProstaglandinG/Hsynthase
product: 321848
reactant: 321800
reactant: 321812
product: 321872
fast: false
product: 321860
reactant: 321824
reversible: false
kinetic law: 321885
reactant: 321836

321848
type: SpeciesReference
stoichiometry: 1.0
species: 378071

321800
type: SpeciesReference
stoichiometry: 1.0
species: 377745

377745
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: arachidonic acid

321812
type: SpeciesReference
stoichiometry: 1.0
species: 378086

378086
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: H+

321872
type: SpeciesReference
stoichiometry: 1.0
species: 378392

378392
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Prostaglandin H2

321860
type: SpeciesReference
stoichiometry: 1.0
species: 378233

378233
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Nicotinamide adenine dinucleotide phosphate

321824
type: SpeciesReference
stoichiometry: 1.0
species: 378242

378242
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Nicotinamide adenine dinucleotide phosphate - reduced

382553
type: LocalParameter
units: 304591
value: 0.0

382551
type: LocalParameter
units: 304591
value: 0.0

382549
type: LocalParameter
units: 304591
value: 1000.0

382547
type: LocalParameter
units: 304591
value: 0.0

321836
type: SpeciesReference
stoichiometry: 2.0
species: 378275

378275
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: O2

379629
type: Reaction
kinetic law: 324646
reactant: 324634
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382938
type: LocalParameter
units: 304591
value: 0.0

382937
type: LocalParameter
units: 304591
value: 0.0

382936
type: LocalParameter
units: 304591
value: 13.5135135135135

382935
type: LocalParameter
units: 304591
value: 0.0

324634
type: SpeciesReference
stoichiometry: 1.0
species: 378188

378188
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Methionine

379158
type: Reaction
reversible: false
product: 316477
reactant: 316453
product: 316489
fast: false
name: phosphatetransportin/outviathreeNa+symporter(irreversible)
notes: GENE_ASSOCIATION: (10786.1) SUBSYSTEM: Transport, Extracellular
kinetic law: 316501
reactant: 316465

316477
type: SpeciesReference
stoichiometry: 3.0
species: 378206

316453
type: SpeciesReference
stoichiometry: 3.0
species: 378209

316489
type: SpeciesReference
stoichiometry: 1.0
species: 378338

381838
type: LocalParameter
units: 304591
value: 0.0

381836
type: LocalParameter
units: 304591
value: 0.0

381834
type: LocalParameter
units: 304591
value: 1000.0

381832
type: LocalParameter
units: 304591
value: 0.0

316465
type: SpeciesReference
stoichiometry: 1.0
species: 378341

378341
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Phosphate

377751
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Arginine

378774
type: Reaction
kinetic law: 308389
product: 308377
reactant: 308365
notes: GENE_ASSOCIATION: (6584.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: L-carnitinereversibletransport

380664
type: LocalParameter
units: 304591
value: 0.0

380661
type: LocalParameter
units: 304591
value: 0.0

380658
type: LocalParameter
units: 304591
value: 1000.0

380655
type: LocalParameter
units: 304591
value: -1000.0

308377
type: SpeciesReference
stoichiometry: 1.0
species: 377838

377838
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Carnitine

308365
type: SpeciesReference
stoichiometry: 1.0
species: 377841

377841
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Carnitine

378690
type: Reaction
kinetic law: 306941
product: 306928
reactant: 306916
reactant: 306904
notes: GENE_ASSOCIATION: (2739.1) SUBSYSTEM: Pyruvate Metabolism
fast: false
reversible: false
name: lactoylglutathionelyase

380384
type: LocalParameter
units: 304591
value: 0.0

380381
type: LocalParameter
units: 304591
value: 0.0

380378
type: LocalParameter
units: 304591
value: 1000.0

380375
type: LocalParameter
units: 304591
value: 0.0

306928
type: SpeciesReference
stoichiometry: 1.0
species: 378170

378170
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: (R)-S-Lactoylglutathione

306916
type: SpeciesReference
stoichiometry: 1.0
species: 378200

306904
type: SpeciesReference
stoichiometry: 1.0
species: 378017

378017
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Reduced glutathione

378044
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: carbonic acid

378545
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Xanthine

378125
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Isoleucine

378636
type: Reaction
kinetic law: 305850
product: 305837
reactant: 305825
notes: GENE_ASSOCIATION: (5236.1) SUBSYSTEM: Pentose Phosphate Pathway
fast: false
reversible: true
name: phosphopentomutase

380110
type: LocalParameter
units: 304591
value: 0.0

380107
type: LocalParameter
units: 304591
value: 0.0

380104
type: LocalParameter
units: 304591
value: 1000.0

380101
type: LocalParameter
units: 304591
value: 0.0

305837
type: SpeciesReference
stoichiometry: 1.0
species: 378419

378419
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: alpha-D-Ribose 5-phosphate

305825
type: SpeciesReference
stoichiometry: 1.0
species: 378416

378416
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: alpha-D-Ribose 1-phosphate

378924
type: Reaction
reactant: 311544
notes: GENE_ASSOCIATION: (1644.1) SUBSYSTEM: Tryptophan metabolism
name: L-Tryptophandecarboxy-lyase
product: 311580
product: 311568
reversible: false
fast: false
reactant: 311556
kinetic law: 311592

311544
type: SpeciesReference
stoichiometry: 1.0
species: 378077

311580
type: SpeciesReference
stoichiometry: 1.0
species: 378512

311568
type: SpeciesReference
stoichiometry: 1.0
species: 377817

311556
type: SpeciesReference
stoichiometry: 1.0
species: 378506

381164
type: LocalParameter
units: 304591
value: 0.0

381161
type: LocalParameter
units: 304591
value: 0.0

381158
type: LocalParameter
units: 304591
value: 1000.0

381155
type: LocalParameter
units: 304591
value: 0.0

377951
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Glucose

379068
type: Reaction
kinetic law: 314641
product: 314629
reactant: 314617
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: false
name: 25-hydroxyvitaminD3transportincytoplasm

381629
type: LocalParameter
units: 304591
value: 0.0

381627
type: LocalParameter
units: 304591
value: 0.0

381625
type: LocalParameter
units: 304591
value: 1000.0

381623
type: LocalParameter
units: 304591
value: 0.0

314629
type: SpeciesReference
stoichiometry: 1.0
species: 377595

377595
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 25-Hydroxyvitamin D3

314617
type: SpeciesReference
stoichiometry: 1.0
species: 377598

377598
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: 25-Hydroxyvitamin D3

378972
type: Reaction
kinetic law: 312595
product: 312570
reactant: 312545
reactant: 312533
notes: GENE_ASSOCIATION: (51181.1) SUBSYSTEM: Pentose and Glucuronate Interconversions
reactant: 312558
name: xylulosereductase
fast: false
reversible: true
product: 312583

381324
type: LocalParameter
units: 304591
value: 0.0

381321
type: LocalParameter
units: 304591
value: 0.0

381318
type: LocalParameter
units: 304591
value: 1000.0

381315
type: LocalParameter
units: 304591
value: -1000.0

312570
type: SpeciesReference
stoichiometry: 1.0
species: 378227

378227
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Nicotinamide adenine dinucleotide phosphate

312545
type: SpeciesReference
stoichiometry: 1.0
species: 378236

378236
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Nicotinamide adenine dinucleotide phosphate - reduced

312533
type: SpeciesReference
stoichiometry: 1.0
species: 378077

312558
type: SpeciesReference
stoichiometry: 1.0
species: 378560

312583
type: SpeciesReference
stoichiometry: 1.0
species: 378554

378554
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Xylitol

378353
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Palmitoyl-CoA (n-C16:0CoA)

377694
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Adenosine

379314
type: Reaction
kinetic law: 319194
product: 319182
reactant: 319170
notes: GENE_ASSOCIATION: SUBSYSTEM: R Group Synthesis
fast: false
reversible: true
name: Rgrouptopalmitateconversion

382202
type: LocalParameter
units: 304591
value: 0.0

382200
type: LocalParameter
units: 304591
value: 0.0

382198
type: LocalParameter
units: 304591
value: 1000.0

382196
type: LocalParameter
units: 304591
value: -1000.0

319182
type: SpeciesReference
stoichiometry: 1.0
species: 378353

319170
type: SpeciesReference
stoichiometry: 1.0
species: 377649

377721
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: D-Alanine

378753
type: Reaction
kinetic law: 308017
product: 308005
reactant: 307992
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: acetaldehydereversibletransport

380594
type: LocalParameter
units: 304591
value: 0.0

380591
type: LocalParameter
units: 304591
value: 0.0

380588
type: LocalParameter
units: 304591
value: 1000.0

380585
type: LocalParameter
units: 304591
value: -1000.0

308005
type: SpeciesReference
stoichiometry: 1.0
species: 377661

377661
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Acetaldehyde

307992
type: SpeciesReference
stoichiometry: 1.0
species: 377664

378903
type: Reaction
product: 311069
reversible: false
product: 311081
reactant: 311057
notes: GENE_ASSOCIATION: (81537.1) SUBSYSTEM: Sphingolipid Metabolism
reactant: 311045
fast: false
kinetic law: 311094
name: sphingoidbase-phosphatephosphatase(sphinganine1-phosphatase),endoplasmicreticulum

311069
type: SpeciesReference
stoichiometry: 1.0
species: 378350

378350
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Phosphate

311081
type: SpeciesReference
stoichiometry: 1.0
species: 378470

378470
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Sphinganine

311057
type: SpeciesReference
stoichiometry: 1.0
species: 378464

378464
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Sphinganine 1-phosphate

311045
type: SpeciesReference
stoichiometry: 1.0
species: 378071

381094
type: LocalParameter
units: 304591
value: 0.0

381091
type: LocalParameter
units: 304591
value: 0.0

381088
type: LocalParameter
units: 304591
value: 1000.0

381085
type: LocalParameter
units: 304591
value: 0.0

379215
type: Reaction
reactant: 317453
name: inositoltransportviasodiumsymport
reactant: 317441
product: 317465
notes: GENE_ASSOCIATION: (6526.1) SUBSYSTEM: Transport, Extracellular
reversible: true
kinetic law: 317489
fast: false
product: 317477

317453
type: SpeciesReference
stoichiometry: 1.0
species: 378209

317441
type: SpeciesReference
stoichiometry: 1.0
species: 378131

378131
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: myo-Inositol

317465
type: SpeciesReference
stoichiometry: 1.0
species: 378128

378128
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: myo-Inositol

381971
type: LocalParameter
units: 304591
value: 0.0

381969
type: LocalParameter
units: 304591
value: 0.0

381967
type: LocalParameter
units: 304591
value: 1000.0

381965
type: LocalParameter
units: 304591
value: -1000.0

317477
type: SpeciesReference
stoichiometry: 1.0
species: 378206

377559
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 10-Formyltetrahydrofolate

378918
type: Reaction
notes: GENE_ASSOCIATION: (2746.1) SUBSYSTEM: Glutamate metabolism
reactant: 311384
reactant: 311396
reversible: true
product: 311420
fast: false
kinetic law: 311456
name: glutamatedehydrogenase(NADP),mitochondrial
product: 311408
product: 311444
product: 311432
reactant: 311372

311384
type: SpeciesReference
stoichiometry: 1.0
species: 378065

311396
type: SpeciesReference
stoichiometry: 1.0
species: 378230

378230
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Nicotinamide adenine dinucleotide phosphate

311420
type: SpeciesReference
stoichiometry: 1.0
species: 378083

378083
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: H+

381144
type: LocalParameter
units: 304591
value: 0.0

381141
type: LocalParameter
units: 304591
value: 0.0

381138
type: LocalParameter
units: 304591
value: 1000.0

381135
type: LocalParameter
units: 304591
value: -1000.0

311408
type: SpeciesReference
stoichiometry: 1.0
species: 377715

377715
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: 2-Oxoglutarate

311444
type: SpeciesReference
stoichiometry: 1.0
species: 378251

378251
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Ammonium

311432
type: SpeciesReference
stoichiometry: 1.0
species: 378239

378239
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Nicotinamide adenine dinucleotide phosphate - reduced

311372
type: SpeciesReference
stoichiometry: 1.0
species: 377984

377984
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-Glutamate

379545
type: Reaction
fast: false
reactant: 323234
product: 323260
notes: GENE_ASSOCIATION: (8574.1) SUBSYSTEM: Pyruvate Metabolism
product: 323247
reversible: false
name: Propane-1,2-diol:NAD+1-oxidoreductase
reactant: 323221
kinetic law: 323272
reactant: 323208

323234
type: SpeciesReference
stoichiometry: 1.0
species: 378218

323260
type: SpeciesReference
stoichiometry: 1.0
species: 378212

323247
type: SpeciesReference
stoichiometry: 1.0
species: 377562

377562
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: (R)-Propane-1,2-diol

323221
type: SpeciesReference
stoichiometry: 1.0
species: 378152

382756
type: LocalParameter
units: 304591
value: 0.0

382754
type: LocalParameter
units: 304591
value: 0.0

382752
type: LocalParameter
units: 304591
value: 1000.0

382750
type: LocalParameter
units: 304591
value: 0.0

323208
type: SpeciesReference
stoichiometry: 1.0
species: 378077

379389
type: Reaction
kinetic law: 320595
product: 320583
reactant: 320571
notes: GENE_ASSOCIATION: SUBSYSTEM: R Group Synthesis
fast: false
reversible: false
name: Rtotalflux

382377
type: LocalParameter
units: 304591
value: 0.0

382375
type: LocalParameter
units: 304591
value: 0.0

382373
type: LocalParameter
units: 304591
value: 1000.0

382371
type: LocalParameter
units: 304591
value: 0.0

320583
type: SpeciesReference
stoichiometry: 1.0
species: 377649

320571
type: SpeciesReference
stoichiometry: 1.0
species: 377643

379047
type: Reaction
name: pyridoxaldehydrogenase
reactant: 314127
reactant: 314139
notes: GENE_ASSOCIATION: (316.1) SUBSYSTEM: Vitamin B6 Metabolism
fast: false
reactant: 314115
kinetic law: 314175
product: 314163
reversible: false
product: 314151

314127
type: SpeciesReference
stoichiometry: 1.0
species: 378266

378266
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: O2

314139
type: SpeciesReference
stoichiometry: 1.0
species: 378398

378398
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Pyridoxal

314115
type: SpeciesReference
stoichiometry: 1.0
species: 378059

381573
type: LocalParameter
units: 304591
value: 0.0

381571
type: LocalParameter
units: 304591
value: 0.0

381568
type: LocalParameter
units: 304591
value: 1000.0

381565
type: LocalParameter
units: 304591
value: 0.0

314163
type: SpeciesReference
stoichiometry: 1.0
species: 378047

314151
type: SpeciesReference
stoichiometry: 1.0
species: 377628

377628
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 4-Pyridoxate

379053
type: Reaction
reactant: 314302
product: 314327
reactant: 314289
reversible: false
fast: false
name: phosphatidylinositol-4,5-bisphosphate4-phosphatase
notes: GENE_ASSOCIATION: SUBSYSTEM: Inositol Phosphate Metabolism
kinetic law: 314339
product: 314315

314302
type: SpeciesReference
stoichiometry: 1.0
species: 378308

314327
type: SpeciesReference
stoichiometry: 1.0
species: 378338

314289
type: SpeciesReference
stoichiometry: 1.0
species: 378059

381591
type: LocalParameter
units: 304591
value: 0.0

381588
type: LocalParameter
units: 304591
value: 0.0

381585
type: LocalParameter
units: 304591
value: 1000.0

381582
type: LocalParameter
units: 304591
value: 0.0

314315
type: SpeciesReference
stoichiometry: 1.0
species: 378320

378011
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Oxidized glutathione

379329
type: Reaction
reactant: 319508
reversible: false
notes: GENE_ASSOCIATION: (3795.1) or (3795.2) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
reactant: 319520
product: 319544
name: ketohexokinase(D-xylulose)
kinetic law: 319568
fast: false
product: 319556
product: 319532

319508
type: SpeciesReference
stoichiometry: 1.0
species: 377769

319520
type: SpeciesReference
stoichiometry: 1.0
species: 378557

378557
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Xylulose

319544
type: SpeciesReference
stoichiometry: 1.0
species: 378077

382237
type: LocalParameter
units: 304591
value: 0.0

382235
type: LocalParameter
units: 304591
value: 0.0

382233
type: LocalParameter
units: 304591
value: 1000.0

382231
type: LocalParameter
units: 304591
value: 0.0

319556
type: SpeciesReference
stoichiometry: 1.0
species: 378548

378548
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Xylulose 1-phosphate

319532
type: SpeciesReference
stoichiometry: 1.0
species: 377700

379284
type: Reaction
reactant: 318627
product: 318663
kinetic law: 318687
product: 318675
reversible: true
reactant: 318615
reactant: 318639
name: Na+-K+-Cl-cotransport
fast: false
notes: GENE_ASSOCIATION: (6557.1) SUBSYSTEM: Transport, Extracellular
product: 318651

318627
type: SpeciesReference
stoichiometry: 1.0
species: 378143

378143
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: potassium

318663
type: SpeciesReference
stoichiometry: 1.0
species: 378140

378140
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: potassium

382132
type: LocalParameter
units: 304591
value: 0.0

382130
type: LocalParameter
units: 304591
value: 0.0

382128
type: LocalParameter
units: 304591
value: 1000.0

382126
type: LocalParameter
units: 304591
value: 0.0

318675
type: SpeciesReference
stoichiometry: 1.0
species: 378206

318615
type: SpeciesReference
stoichiometry: 2.0
species: 377814

377814
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Chloride

318639
type: SpeciesReference
stoichiometry: 1.0
species: 378209

318651
type: SpeciesReference
stoichiometry: 2.0
species: 377811

377811
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Chloride

379299
type: Reaction
kinetic law: 319001
product: 318989
reactant: 318977
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: false
name: gulonolactoneendoplasmicreticulartransport

382167
type: LocalParameter
units: 304591
value: 0.0

382165
type: LocalParameter
units: 304591
value: 0.0

382163
type: LocalParameter
units: 304591
value: 1000.0

382161
type: LocalParameter
units: 304591
value: 0.0

318989
type: SpeciesReference
stoichiometry: 1.0
species: 378035

378035
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: L-Gulono-1,4-lactone

318977
type: SpeciesReference
stoichiometry: 1.0
species: 378032

378032
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Gulono-1,4-lactone

377990
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Glyoxylate

378422
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: cis-13-retinal

378299
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Oxalate

377957
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: D-Glucose

378038
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Gulonate

379524
type: Reaction
kinetic law: 322913
product: 322901
reactant: 322889
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: intracellulartransport

382707
type: LocalParameter
units: 304591
value: 0.0

382705
type: LocalParameter
units: 304591
value: 0.0

382703
type: LocalParameter
units: 304591
value: 1000.0

382701
type: LocalParameter
units: 304591
value: -1000.0

322901
type: SpeciesReference
stoichiometry: 1.0
species: 377745

322889
type: SpeciesReference
stoichiometry: 1.0
species: 377739

377739
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: arachidonic acid

377580
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 3-Phospho-D-glyceroyl phosphate

379530
type: Reaction
reactant: 322998
reversible: false
reactant: 323010
product: 323022
kinetic law: 323046
product: 323034
notes: GENE_ASSOCIATION: SUBSYSTEM: Pyrimidine Catabolism
fast: false
name: 2-deoxy-D-ribose1-phosphatephosphorylase

322998
type: SpeciesReference
stoichiometry: 1.0
species: 377604

377604
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 2-Deoxy-D-ribose 1-phosphate

323010
type: SpeciesReference
stoichiometry: 1.0
species: 378059

323022
type: SpeciesReference
stoichiometry: 1.0
species: 377886

377886
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Deoxyribose

382721
type: LocalParameter
units: 304591
value: 0.0

382719
type: LocalParameter
units: 304591
value: 0.0

382717
type: LocalParameter
units: 304591
value: 1000.0

382715
type: LocalParameter
units: 304591
value: 0.0

323034
type: SpeciesReference
stoichiometry: 1.0
species: 378338

379788
type: Reaction
kinetic law: 325925
reactant: 325913
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Lysineexchange

383150
type: LocalParameter
units: 304591
value: 0.0

383149
type: LocalParameter
units: 304591
value: 0.0

383148
type: LocalParameter
units: 304591
value: 0.0

383147
type: LocalParameter
units: 304591
value: -1000.0

325913
type: SpeciesReference
stoichiometry: 1.0
species: 378176

378176
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Lysine

379308
type: Reaction
kinetic law: 319110
product: 319098
reactant: 319086
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: O2transport,peroxisomal

382188
type: LocalParameter
units: 304591
value: 0.0

382186
type: LocalParameter
units: 304591
value: 0.0

382184
type: LocalParameter
units: 304591
value: 1000.0

382182
type: LocalParameter
units: 304591
value: -1000.0

319098
type: SpeciesReference
stoichiometry: 1.0
species: 378278

319086
type: SpeciesReference
stoichiometry: 1.0
species: 378266

379401
type: Reaction
reversible: false
reactant: 320799
notes: GENE_ASSOCIATION: (116255.1) or (80168.1) SUBSYSTEM: Triacylglycerol Synthesis
reactant: 320811
kinetic law: 320847
product: 320823
fast: false
product: 320835
name: monoacylglycerolacyltransferase

320799
type: SpeciesReference
stoichiometry: 1.0
species: 377649

320811
type: SpeciesReference
stoichiometry: 1.0
species: 378179

378179
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: monoacylglycerol 2 (homo sapiens)

382405
type: LocalParameter
units: 304591
value: 0.0

382403
type: LocalParameter
units: 304591
value: 0.0

382401
type: LocalParameter
units: 304591
value: 1000.0

382399
type: LocalParameter
units: 304591
value: 0.0

320823
type: SpeciesReference
stoichiometry: 1.0
species: 377826

377826
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Coenzyme A

320835
type: SpeciesReference
stoichiometry: 1.0
species: 377862

377862
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: diacylglycerol (homo sapiens)

379278
type: Reaction
kinetic law: 318542
product: 318530
reactant: 318518
notes: GENE_ASSOCIATION: (117247.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: L-tryptophantransport

382118
type: LocalParameter
units: 304591
value: 0.0

382116
type: LocalParameter
units: 304591
value: 0.0

382114
type: LocalParameter
units: 304591
value: 1000.0

382112
type: LocalParameter
units: 304591
value: 0.0

318530
type: SpeciesReference
stoichiometry: 1.0
species: 378506

318518
type: SpeciesReference
stoichiometry: 1.0
species: 378509

378509
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Tryptophan

379593
type: Reaction
kinetic law: 324358
reactant: 324346
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382868
type: LocalParameter
units: 304591
value: 0.0

382866
type: LocalParameter
units: 304591
value: 0.0

382864
type: LocalParameter
units: 304591
value: 13.5135135135135

382862
type: LocalParameter
units: 304591
value: 0.0

324346
type: SpeciesReference
stoichiometry: 1.0
species: 378569

378569
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545

377927
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Fructose

379632
type: Reaction
kinetic law: 324671
reactant: 324659
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382942
type: LocalParameter
units: 304591
value: 0.0

382941
type: LocalParameter
units: 304591
value: 0.0

382940
type: LocalParameter
units: 304591
value: 13.5135135135135

382939
type: LocalParameter
units: 304591
value: 0.0

324659
type: SpeciesReference
stoichiometry: 1.0
species: 378173

378173
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Lysine

379470
type: Reaction
reactant: 322006
name: catalaseA,peroxisomal(ethanol)
product: 322043
reversible: false
product: 322030
notes: GENE_ASSOCIATION: (847.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
kinetic law: 322055
reactant: 322018

322006
type: SpeciesReference
stoichiometry: 1.0
species: 377901

377901
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Ethanol

322043
type: SpeciesReference
stoichiometry: 2.0
species: 378074

378074
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: H2O

322030
type: SpeciesReference
stoichiometry: 1.0
species: 377670

377670
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Acetaldehyde

382581
type: LocalParameter
units: 304591
value: 0.0

382579
type: LocalParameter
units: 304591
value: 0.0

382577
type: LocalParameter
units: 304591
value: 1000.0

382575
type: LocalParameter
units: 304591
value: 0.0

322018
type: SpeciesReference
stoichiometry: 1.0
species: 378056

378582
type: Reaction
reversible: false
kinetic law: 304771
name: fructose-bisphosphatase
product: 304759
notes: GENE_ASSOCIATION: (2203.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
reactant: 304735
product: 304747
reactant: 304723

379930
type: LocalParameter
units: 304591
value: 0.0

379927
type: LocalParameter
units: 304591
value: 0.0

379924
type: LocalParameter
units: 304591
value: 1000.0

379921
type: LocalParameter
units: 304591
value: 0.0

304759
type: SpeciesReference
stoichiometry: 1.0
species: 378338

304735
type: SpeciesReference
stoichiometry: 1.0
species: 378059

304747
type: SpeciesReference
stoichiometry: 1.0
species: 377905

377905
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Fructose 6-phosphate

304723
type: SpeciesReference
stoichiometry: 1.0
species: 377914

378618
type: Reaction
reversible: true
name: transketolase
reactant: 305389
fast: false
product: 305425
kinetic law: 305437
notes: GENE_ASSOCIATION: (7086.1) SUBSYSTEM: Pentose Phosphate Pathway
reactant: 305401
product: 305413

305389
type: SpeciesReference
stoichiometry: 1.0
species: 377892

377892
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Erythrose 4-phosphate

305425
type: SpeciesReference
stoichiometry: 1.0
species: 377933

377933
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Glyceraldehyde 3-phosphate

380050
type: LocalParameter
units: 304591
value: 0.0

380047
type: LocalParameter
units: 304591
value: 0.0

380044
type: LocalParameter
units: 304591
value: 1000.0

380041
type: LocalParameter
units: 304591
value: 0.0

305401
type: SpeciesReference
stoichiometry: 1.0
species: 378551

378551
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Xylulose 5-phosphate

305413
type: SpeciesReference
stoichiometry: 1.0
species: 377905

377631
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: 4-Pyridoxate

379767
type: Reaction
kinetic law: 325756
reactant: 325744
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Oxidizedglutathioneexchange

383122
type: LocalParameter
units: 304591
value: 0.0

383121
type: LocalParameter
units: 304591
value: 0.0

383120
type: LocalParameter
units: 304591
value: 13.5135135135135

383119
type: LocalParameter
units: 304591
value: -1000.0

325744
type: SpeciesReference
stoichiometry: 1.0
species: 378014

378014
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Oxidized glutathione

379773
type: Reaction
kinetic law: 325804
reactant: 325792
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Deoxyguanosineexchange

383130
type: LocalParameter
units: 304591
value: 0.0

383129
type: LocalParameter
units: 304591
value: 0.0

383128
type: LocalParameter
units: 304591
value: 13.5135135135135

383127
type: LocalParameter
units: 304591
value: -1000.0

325792
type: SpeciesReference
stoichiometry: 1.0
species: 377868

377868
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Deoxyguanosine

378185
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-Malate

378005
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Glycolate

378576
type: Reaction
kinetic law: 304663
product: 304651
product: 304639
reactant: 304627
notes: GENE_ASSOCIATION: (2023.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
reversible: true
name: enolase

379910
type: LocalParameter
units: 304591
value: 0.0

379907
type: LocalParameter
units: 304591
value: 0.0

379904
type: LocalParameter
units: 304591
value: 1000.0

379901
type: LocalParameter
units: 304591
value: -1000.0

304651
type: SpeciesReference
stoichiometry: 1.0
species: 378329

378329
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Phosphoenolpyruvate

304639
type: SpeciesReference
stoichiometry: 1.0
species: 378059

304627
type: SpeciesReference
stoichiometry: 1.0
species: 377610

377610
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Glycerate 2-phosphate

379539
type: Reaction
kinetic law: 323156
product: 323144
reactant: 323131
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: sph1pintracellulartransport

382742
type: LocalParameter
units: 304591
value: 0.0

382740
type: LocalParameter
units: 304591
value: 0.0

382738
type: LocalParameter
units: 304591
value: 1000.0

382736
type: LocalParameter
units: 304591
value: -1000.0

323144
type: SpeciesReference
stoichiometry: 1.0
species: 378464

323131
type: SpeciesReference
stoichiometry: 1.0
species: 378461

378461
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Sphinganine 1-phosphate

378603
type: Reaction
kinetic law: 305182
product: 305170
reactant: 305158
notes: GENE_ASSOCIATION: (7167.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
reversible: true
name: triose-phosphateisomerase

380000
type: LocalParameter
units: 304591
value: 0.0

379997
type: LocalParameter
units: 304591
value: 0.0

379994
type: LocalParameter
units: 304591
value: 1000.0

379991
type: LocalParameter
units: 304591
value: -1000.0

305170
type: SpeciesReference
stoichiometry: 1.0
species: 377933

305158
type: SpeciesReference
stoichiometry: 1.0
species: 377871

377871
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Dihydroxyacetone phosphate

378332
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Phenylalanine

377829
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Coenzyme A

379350
type: Reaction
kinetic law: 319833
product: 319821
reactant: 319809
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: glycinepassivetransporttoperoxisome

382286
type: LocalParameter
units: 304591
value: 0.0

382284
type: LocalParameter
units: 304591
value: 0.0

382282
type: LocalParameter
units: 304591
value: 1000.0

382280
type: LocalParameter
units: 304591
value: -1000.0

319821
type: SpeciesReference
stoichiometry: 1.0
species: 377999

377999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Glycine

319809
type: SpeciesReference
stoichiometry: 1.0
species: 377993

377993
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Glycine

379107
type: Reaction
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
kinetic law: 315390
reactant: 315340
reversible: true
name: D-Serine/Glutaminereversibleexchange
product: 315377
fast: false
product: 315365
reactant: 315353

381720
type: LocalParameter
units: 304591
value: 0.0

381718
type: LocalParameter
units: 304591
value: 0.0

381716
type: LocalParameter
units: 304591
value: 1000.0

381714
type: LocalParameter
units: 304591
value: -1000.0

315340
type: SpeciesReference
stoichiometry: 1.0
species: 377966

377966
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Glutamine

315377
type: SpeciesReference
stoichiometry: 1.0
species: 378449

378449
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Serine

315365
type: SpeciesReference
stoichiometry: 1.0
species: 377969

377969
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Glutamine

315353
type: SpeciesReference
stoichiometry: 1.0
species: 378452

378452
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: D-Serine

378633
type: Reaction
notes: GENE_ASSOCIATION: (64080.1) SUBSYSTEM: Pentose Phosphate Pathway
product: 305776
reactant: 305764
reactant: 305752
kinetic law: 305812
product: 305788
name: ribokinase
product: 305800
reversible: false
fast: false

305776
type: SpeciesReference
stoichiometry: 1.0
species: 377700

305764
type: SpeciesReference
stoichiometry: 1.0
species: 378434

305752
type: SpeciesReference
stoichiometry: 1.0
species: 377769

380100
type: LocalParameter
units: 304591
value: 0.0

380097
type: LocalParameter
units: 304591
value: 0.0

380094
type: LocalParameter
units: 304591
value: 1000.0

380091
type: LocalParameter
units: 304591
value: 0.0

305788
type: SpeciesReference
stoichiometry: 1.0
species: 378077

305800
type: SpeciesReference
stoichiometry: 1.0
species: 378419

378834
type: Reaction
product: 309488
reversible: false
notes: GENE_ASSOCIATION: (6647.1) SUBSYSTEM: ROS Detoxification
reactant: 309476
reactant: 309464
product: 309500
kinetic law: 309512
name: superoxidedismutase
fast: false

309488
type: SpeciesReference
stoichiometry: 1.0
species: 378047

309476
type: SpeciesReference
stoichiometry: 2.0
species: 378281

378281
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Superoxide anion

309464
type: SpeciesReference
stoichiometry: 2.0
species: 378077

309500
type: SpeciesReference
stoichiometry: 1.0
species: 378266

380864
type: LocalParameter
units: 304591
value: 0.0

380861
type: LocalParameter
units: 304591
value: 0.0

380858
type: LocalParameter
units: 304591
value: 1000.0

380855
type: LocalParameter
units: 304591
value: 0.0

378921
type: Reaction
reactant: 311469
fast: false
name: alcoholdehydrogenase(ethanol,NADP),forwardreaction
product: 311507
reversible: false
product: 311519
notes: GENE_ASSOCIATION: (10327.1) or (10327.2) SUBSYSTEM: Glycolysis/Gluconeogenesis
kinetic law: 311532
reactant: 311481
product: 311494

311469
type: SpeciesReference
stoichiometry: 1.0
species: 377895

377895
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Ethanol

311507
type: SpeciesReference
stoichiometry: 1.0
species: 378077

311519
type: SpeciesReference
stoichiometry: 1.0
species: 378236

381154
type: LocalParameter
units: 304591
value: 0.0

381151
type: LocalParameter
units: 304591
value: 0.0

381148
type: LocalParameter
units: 304591
value: 1000.0

381145
type: LocalParameter
units: 304591
value: 0.0

311481
type: SpeciesReference
stoichiometry: 1.0
species: 378227

311494
type: SpeciesReference
stoichiometry: 1.0
species: 377661

378849
type: Reaction
kinetic law: 309793
product: 309769
product: 309756
notes: GENE_ASSOCIATION: (5105.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
reversible: false
reactant: 309743
name: Phosphoenolpyruvatecarboxykinase(GTP)
fast: false
reactant: 309730
product: 309781

380914
type: LocalParameter
units: 304591
value: 0.0

380911
type: LocalParameter
units: 304591
value: 0.0

380908
type: LocalParameter
units: 304591
value: 1000.0

380905
type: LocalParameter
units: 304591
value: 0.0

309769
type: SpeciesReference
stoichiometry: 1.0
species: 377939

309756
type: SpeciesReference
stoichiometry: 1.0
species: 377817

309743
type: SpeciesReference
stoichiometry: 1.0
species: 378290

378290
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Oxaloacetate

309730
type: SpeciesReference
stoichiometry: 1.0
species: 378023

378023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: GTP

309781
type: SpeciesReference
stoichiometry: 1.0
species: 378329

379221
type: Reaction
kinetic law: 317612
reversible: true
notes: GENE_ASSOCIATION: (9058.1) SUBSYSTEM: Transport, Extracellular
reactant: 317563
reactant: 317575
fast: false
product: 317599
name: citratetransportviasodiumsymport
product: 317587

381985
type: LocalParameter
units: 304591
value: 0.0

381983
type: LocalParameter
units: 304591
value: 0.0

381981
type: LocalParameter
units: 304591
value: 1000.0

381979
type: LocalParameter
units: 304591
value: 0.0

317563
type: SpeciesReference
stoichiometry: 1.0
species: 377805

377805
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Citrate

317575
type: SpeciesReference
stoichiometry: 2.0
species: 378209

317599
type: SpeciesReference
stoichiometry: 2.0
species: 378206

317587
type: SpeciesReference
stoichiometry: 1.0
species: 377802

377802
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Citrate

377688
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Adenine

377637
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Cystine

378705
type: Reaction
reactant: 307159
reversible: true
fast: false
kinetic law: 307196
name: citratetransport,mitochondrial
product: 307183
reactant: 307147
product: 307171
notes: GENE_ASSOCIATION: (6576.1) SUBSYSTEM: Transport, Mitochondrial

307159
type: SpeciesReference
stoichiometry: 1.0
species: 378185

380434
type: LocalParameter
units: 304591
value: 0.0

380431
type: LocalParameter
units: 304591
value: 0.0

380428
type: LocalParameter
units: 304591
value: 1000.0

380425
type: LocalParameter
units: 304591
value: -1000.0

307183
type: SpeciesReference
stoichiometry: 1.0
species: 378182

378182
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Malate

307147
type: SpeciesReference
stoichiometry: 1.0
species: 377802

307171
type: SpeciesReference
stoichiometry: 1.0
species: 377808

377808
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Citrate

378792
type: Reaction
kinetic law: 308703
product: 308691
reactant: 308679
notes: GENE_ASSOCIATION: (6523.1) or (8170.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: Ureatransportviafacilitatediffusion

380724
type: LocalParameter
units: 304591
value: 0.0

380721
type: LocalParameter
units: 304591
value: 0.0

380718
type: LocalParameter
units: 304591
value: 1000.0

380715
type: LocalParameter
units: 304591
value: 0.0

308691
type: SpeciesReference
stoichiometry: 1.0
species: 378530

308679
type: SpeciesReference
stoichiometry: 1.0
species: 378533

378533
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Urea

378062
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: H2O

378563
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545

378302
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Oxalate

379002
type: Reaction
kinetic law: 313259
product: 313247
reactant: 313234
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: deoxyadenosinetransportviadiffusion

381424
type: LocalParameter
units: 304591
value: 0.0

381421
type: LocalParameter
units: 304591
value: 0.0

381418
type: LocalParameter
units: 304591
value: 1000.0

381415
type: LocalParameter
units: 304591
value: -1000.0

313247
type: SpeciesReference
stoichiometry: 1.0
species: 377856

377856
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Deoxyadenosine

313234
type: SpeciesReference
stoichiometry: 1.0
species: 377859

377859
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Deoxyadenosine

379428
type: Reaction
kinetic law: 321390
product: 321378
reactant: 321366
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: retinoicacidtransport

382468
type: LocalParameter
units: 304591
value: 0.0

382466
type: LocalParameter
units: 304591
value: 0.0

382464
type: LocalParameter
units: 304591
value: 1000.0

382462
type: LocalParameter
units: 304591
value: -1000.0

321378
type: SpeciesReference
stoichiometry: 1.0
species: 378431

378431
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Retinoate

321366
type: SpeciesReference
stoichiometry: 1.0
species: 378428

378428
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Retinoate

379017
type: Reaction
product: 313513
reactant: 313489
product: 313525
reversible: false
name: Glycolateoxidase,peroxisome
reactant: 313501
fast: false
kinetic law: 313537
notes: GENE_ASSOCIATION: (51179.1) or (51179.2) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism

313513
type: SpeciesReference
stoichiometry: 1.0
species: 377990

313489
type: SpeciesReference
stoichiometry: 1.0
species: 378008

378008
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Glycolate

313525
type: SpeciesReference
stoichiometry: 1.0
species: 378056

313501
type: SpeciesReference
stoichiometry: 1.0
species: 378278

381474
type: LocalParameter
units: 304591
value: 0.0

381471
type: LocalParameter
units: 304591
value: 0.0

381468
type: LocalParameter
units: 304591
value: 1000.0

381465
type: LocalParameter
units: 304591
value: 0.0

379332
type: Reaction
kinetic law: 319616
product: 319604
product: 319592
reactant: 319580
notes: GENE_ASSOCIATION: (226.2) or (229.1) or (226.3) or (226.1) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
fast: false
reversible: true
name: D-Fructose1-phosphateD-glyceraldehyde-3-phosphate-lyase

382244
type: LocalParameter
units: 304591
value: 0.0

382242
type: LocalParameter
units: 304591
value: 0.0

382240
type: LocalParameter
units: 304591
value: 1000.0

382238
type: LocalParameter
units: 304591
value: -1000.0

319604
type: SpeciesReference
stoichiometry: 1.0
species: 377936

377936
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Glycolaldehyde

319592
type: SpeciesReference
stoichiometry: 1.0
species: 377871

319580
type: SpeciesReference
stoichiometry: 1.0
species: 378548

379086
type: Reaction
product: 314918
name: L-methioninetransportinviasodiumsymport
reactant: 314894
fast: false
reactant: 314882
notes: GENE_ASSOCIATION: (54407.1) or (6584.1) SUBSYSTEM: Transport, Extracellular
kinetic law: 314930
reversible: false
product: 314906

314918
type: SpeciesReference
stoichiometry: 1.0
species: 378206

314894
type: SpeciesReference
stoichiometry: 1.0
species: 378209

314882
type: SpeciesReference
stoichiometry: 1.0
species: 378191

378191
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Methionine

381671
type: LocalParameter
units: 304591
value: 0.0

381669
type: LocalParameter
units: 304591
value: 0.0

381667
type: LocalParameter
units: 304591
value: 1000.0

381665
type: LocalParameter
units: 304591
value: 0.0

314906
type: SpeciesReference
stoichiometry: 1.0
species: 378188

378828
type: Reaction
product: 309356
notes: GENE_ASSOCIATION: (5151.4) or (5151.5) or (5151.3) or (5151.1) or (5151.2) SUBSYSTEM: Nucleotides
product: 309368
reactant: 309332
name: 3',5'-cyclic-nucleotidephosphodiesterase
fast: false
kinetic law: 309380
reactant: 309344
reversible: false

309356
type: SpeciesReference
stoichiometry: 1.0
species: 377730

377730
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: AMP

309368
type: SpeciesReference
stoichiometry: 1.0
species: 378077

309332
type: SpeciesReference
stoichiometry: 1.0
species: 377787

377787
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: cAMP

380844
type: LocalParameter
units: 304591
value: 0.0

380841
type: LocalParameter
units: 304591
value: 0.0

380838
type: LocalParameter
units: 304591
value: 1000.0

380835
type: LocalParameter
units: 304591
value: 0.0

309344
type: SpeciesReference
stoichiometry: 1.0
species: 378059

378990
type: Reaction
reactant: 312945
reactant: 312957
fast: false
kinetic law: 313005
reversible: false
product: 312993
product: 312981
name: dehydroascorbatereductase
reactant: 312969
notes: GENE_ASSOCIATION: (2745.1) SUBSYSTEM: Ascorbate and Aldarate Metabolism

312945
type: SpeciesReference
stoichiometry: 1.0
species: 377874

312957
type: SpeciesReference
stoichiometry: 1.0
species: 378077

381384
type: LocalParameter
units: 304591
value: 0.0

381381
type: LocalParameter
units: 304591
value: 0.0

381378
type: LocalParameter
units: 304591
value: 1000.0

381375
type: LocalParameter
units: 304591
value: 0.0

312993
type: SpeciesReference
stoichiometry: 1.0
species: 378227

312981
type: SpeciesReference
stoichiometry: 1.0
species: 377754

377754
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Ascorbate

312969
type: SpeciesReference
stoichiometry: 1.0
species: 378236

379659
type: Reaction
kinetic law: 324887
reactant: 324875
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382978
type: LocalParameter
units: 304591
value: 0.0

382977
type: LocalParameter
units: 304591
value: 0.0

382976
type: LocalParameter
units: 304591
value: 13.5135135135135

382975
type: LocalParameter
units: 304591
value: 0.0

324875
type: SpeciesReference
stoichiometry: 1.0
species: 377757

377757
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Asparagine

378389
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Prostaglandin H2

379248
type: Reaction
kinetic law: 318060
product: 318048
reactant: 318036
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: fattyacidtransportviadiffusion

382048
type: LocalParameter
units: 304591
value: 0.0

382046
type: LocalParameter
units: 304591
value: 0.0

382044
type: LocalParameter
units: 304591
value: 1000.0

382042
type: LocalParameter
units: 304591
value: -1000.0

318048
type: SpeciesReference
stoichiometry: 1.0
species: 378260

378260
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: nervonic acid

318036
type: SpeciesReference
stoichiometry: 1.0
species: 378263

379839
type: Reaction
kinetic law: 326334
reactant: 326322
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: K+exchange

383218
type: LocalParameter
units: 304591
value: 0.0

383217
type: LocalParameter
units: 304591
value: 0.0

383216
type: LocalParameter
units: 304591
value: 0.0

383215
type: LocalParameter
units: 304591
value: -1000.0

326322
type: SpeciesReference
stoichiometry: 1.0
species: 378143

379326
type: Reaction
notes: GENE_ASSOCIATION: (51179.2) or (51179.1) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
fast: false
name: glyoxylateoxidase,peroxisomal
reactant: 319424
product: 319484
kinetic law: 319496
reactant: 319448
reactant: 319436
product: 319472
reversible: false
product: 319460

319424
type: SpeciesReference
stoichiometry: 1.0
species: 377990

319484
type: SpeciesReference
stoichiometry: 1.0
species: 378305

378305
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Oxalate

382230
type: LocalParameter
units: 304591
value: 0.0

382228
type: LocalParameter
units: 304591
value: 0.0

382226
type: LocalParameter
units: 304591
value: 1000.0

382224
type: LocalParameter
units: 304591
value: 0.0

319448
type: SpeciesReference
stoichiometry: 1.0
species: 378278

319436
type: SpeciesReference
stoichiometry: 1.0
species: 378074

319472
type: SpeciesReference
stoichiometry: 1.0
species: 378089

319460
type: SpeciesReference
stoichiometry: 1.0
species: 378056

378293
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 4-oxo-retonoic acid

378113
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: 4 hydroxy retinoic acid

378648
type: Reaction
reactant: 306048
reactant: 306036
reversible: false
notes: GENE_ASSOCIATION: (132.1) or (132.2) SUBSYSTEM: Nucleotides
kinetic law: 306096
fast: false
product: 306060
product: 306084
product: 306072
name: adenosinekinase

306048
type: SpeciesReference
stoichiometry: 1.0
species: 377769

306036
type: SpeciesReference
stoichiometry: 1.0
species: 377694

380150
type: LocalParameter
units: 304591
value: 0.0

380147
type: LocalParameter
units: 304591
value: 0.0

380144
type: LocalParameter
units: 304591
value: 1000.0

380141
type: LocalParameter
units: 304591
value: 0.0

306060
type: SpeciesReference
stoichiometry: 1.0
species: 377700

306084
type: SpeciesReference
stoichiometry: 1.0
species: 378077

306072
type: SpeciesReference
stoichiometry: 1.0
species: 377730

378936
type: Reaction
reactant: 311832
reactant: 311856
product: 311892
name: glutamate-5-semialdehydedehydrogenase(m)
kinetic law: 311904
reversible: false
fast: false
product: 311868
product: 311880
notes: GENE_ASSOCIATION: (5832.1) SUBSYSTEM: Urea cycle/amino group metabolism
reactant: 311844

311832
type: SpeciesReference
stoichiometry: 1.0
species: 377972

311856
type: SpeciesReference
stoichiometry: 1.0
species: 378239

311892
type: SpeciesReference
stoichiometry: 1.0
species: 378344

378344
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Phosphate

381204
type: LocalParameter
units: 304591
value: 0.0

381201
type: LocalParameter
units: 304591
value: 0.0

381198
type: LocalParameter
units: 304591
value: 1000.0

381195
type: LocalParameter
units: 304591
value: 0.0

311868
type: SpeciesReference
stoichiometry: 1.0
species: 377975

377975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-Glutamate 5-semialdehyde

311880
type: SpeciesReference
stoichiometry: 1.0
species: 378230

311844
type: SpeciesReference
stoichiometry: 1.0
species: 378083

379065
type: Reaction
kinetic law: 314605
product: 314593
reactant: 314581
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: false

381622
type: LocalParameter
units: 304591
value: 0.0

381620
type: LocalParameter
units: 304591
value: 0.0

381618
type: LocalParameter
units: 304591
value: 1000.0

381616
type: LocalParameter
units: 304591
value: 0.0

314593
type: SpeciesReference
stoichiometry: 1.0
species: 377598

314581
type: SpeciesReference
stoichiometry: 1.0
species: 377595

378681
type: Reaction
notes: GENE_ASSOCIATION: (8802.1 and 8801.1) SUBSYSTEM: Citric Acid Cycle
product: 306735
reactant: 306723
reversible: true
kinetic law: 306771
product: 306747
reactant: 306699
product: 306759
reactant: 306711
name: Succinate--CoAligase(GDP-forming)
fast: false

306735
type: SpeciesReference
stoichiometry: 1.0
species: 377942

377942
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: GDP

306723
type: SpeciesReference
stoichiometry: 1.0
species: 378491

378491
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Succinate

380354
type: LocalParameter
units: 304591
value: 0.0

380351
type: LocalParameter
units: 304591
value: 0.0

380348
type: LocalParameter
units: 304591
value: 0.0

380345
type: LocalParameter
units: 304591
value: -1000.0

306747
type: SpeciesReference
stoichiometry: 1.0
species: 378344

306699
type: SpeciesReference
stoichiometry: 1.0
species: 377829

306759
type: SpeciesReference
stoichiometry: 1.0
species: 378494

378494
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Succinyl-CoA

306711
type: SpeciesReference
stoichiometry: 1.0
species: 378026

378026
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: GTP

378359
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Diphosphate

379563
type: Reaction
kinetic law: 323488
product: 323476
reactant: 323464
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true

382798
type: LocalParameter
units: 304591
value: 0.0

382796
type: LocalParameter
units: 304591
value: 0.0

382794
type: LocalParameter
units: 304591
value: 1000.0

382792
type: LocalParameter
units: 304591
value: -1000.0

323476
type: SpeciesReference
stoichiometry: 1.0
species: 378566

323464
type: SpeciesReference
stoichiometry: 1.0
species: 378563

379311
type: Reaction
kinetic law: 319158
product: 319146
reactant: 319134
reactant: 319122
notes: GENE_ASSOCIATION: SUBSYSTEM: R Group Synthesis
fast: false
reversible: true
name: Rgroupcoenzymealigase

382195
type: LocalParameter
units: 304591
value: 0.0

382193
type: LocalParameter
units: 304591
value: 0.0

382191
type: LocalParameter
units: 304591
value: 1000.0

382189
type: LocalParameter
units: 304591
value: -1000.0

319146
type: SpeciesReference
stoichiometry: 1.0
species: 377649

319134
type: SpeciesReference
stoichiometry: 1.0
species: 377826

319122
type: SpeciesReference
stoichiometry: 1.0
species: 377646

377646
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: R total

379227
type: Reaction
product: 317721
product: 317709
reversible: true
kinetic law: 317733
fast: false
reactant: 317685
notes: GENE_ASSOCIATION: (64849.1) or (64849.2) SUBSYSTEM: Transport, Extracellular
reactant: 317697
name: succinatetransportviasodiumsymport

317721
type: SpeciesReference
stoichiometry: 1.0
species: 378485

378485
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Succinate

317709
type: SpeciesReference
stoichiometry: 3.0
species: 378206

381999
type: LocalParameter
units: 304591
value: 0.0

381997
type: LocalParameter
units: 304591
value: 0.0

381995
type: LocalParameter
units: 304591
value: 1000.0

381993
type: LocalParameter
units: 304591
value: -1000.0

317685
type: SpeciesReference
stoichiometry: 3.0
species: 378209

317697
type: SpeciesReference
stoichiometry: 1.0
species: 378488

378488
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Succinate

379542
type: Reaction
kinetic law: 323195
product: 323182
reactant: 323169
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: sphingosine-1-phosphatetransport

382749
type: LocalParameter
units: 304591
value: 0.0

382747
type: LocalParameter
units: 304591
value: 0.0

382745
type: LocalParameter
units: 304591
value: 1000.0

382743
type: LocalParameter
units: 304591
value: -1000.0

323182
type: SpeciesReference
stoichiometry: 1.0
species: 378482

323169
type: SpeciesReference
stoichiometry: 1.0
species: 378479

378479
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Sphingosine 1-phosphate

379557
type: Reaction
kinetic law: 323416
product: 323404
reactant: 323392
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: hydrogenperoxidetransportviadiffusion

382784
type: LocalParameter
units: 304591
value: 0.0

382782
type: LocalParameter
units: 304591
value: 0.0

382780
type: LocalParameter
units: 304591
value: 1000.0

382778
type: LocalParameter
units: 304591
value: -1000.0

323404
type: SpeciesReference
stoichiometry: 1.0
species: 378047

323392
type: SpeciesReference
stoichiometry: 1.0
species: 378050

378050
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Hydrogen peroxide

379059
type: Reaction
reactant: 314436
notes: GENE_ASSOCIATION: (81537.1) SUBSYSTEM: Sphingolipid Metabolism
name: sphingoidbase-phosphatephosphatase(sphinganine1-phosphatase),endoplasmicreticulum
reversible: false
reactant: 314423
product: 314448
kinetic law: 314472
fast: false
product: 314460

314436
type: SpeciesReference
stoichiometry: 1.0
species: 378482

314423
type: SpeciesReference
stoichiometry: 1.0
species: 378071

314448
type: SpeciesReference
stoichiometry: 1.0
species: 378350

381608
type: LocalParameter
units: 304591
value: 0.0

381606
type: LocalParameter
units: 304591
value: 0.0

381604
type: LocalParameter
units: 304591
value: 1000.0

381601
type: LocalParameter
units: 304591
value: 0.0

314460
type: SpeciesReference
stoichiometry: 1.0
species: 378476

378476
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Sphingosine

378621
type: Reaction
reactant: 305462
reactant: 305449
kinetic law: 305498
fast: false
product: 305486
notes: GENE_ASSOCIATION: (10840.1) SUBSYSTEM: Fatty Acid Metabolism
name: formatedehydrogenase
product: 305474
reversible: false

305462
type: SpeciesReference
stoichiometry: 1.0
species: 378212

305449
type: SpeciesReference
stoichiometry: 1.0
species: 377923

377923
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Formate

380060
type: LocalParameter
units: 304591
value: 0.0

380057
type: LocalParameter
units: 304591
value: 0.0

380054
type: LocalParameter
units: 304591
value: 1000.0

380051
type: LocalParameter
units: 304591
value: 0.0

305486
type: SpeciesReference
stoichiometry: 1.0
species: 378218

305474
type: SpeciesReference
stoichiometry: 1.0
species: 377817

379296
type: Reaction
product: 318941
reversible: true
reactant: 318917
product: 318953
reactant: 318892
name: Na+-K+-Cl-cotransport(NH4+)
fast: false
notes: GENE_ASSOCIATION: (6557.1) SUBSYSTEM: Transport, Extracellular
reactant: 318905
kinetic law: 318965
product: 318929

318941
type: SpeciesReference
stoichiometry: 1.0
species: 378206

318917
type: SpeciesReference
stoichiometry: 1.0
species: 378248

318953
type: SpeciesReference
stoichiometry: 1.0
species: 378245

378245
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Ammonium

318892
type: SpeciesReference
stoichiometry: 2.0
species: 377814

318905
type: SpeciesReference
stoichiometry: 1.0
species: 378209

382160
type: LocalParameter
units: 304591
value: 0.0

382158
type: LocalParameter
units: 304591
value: 0.0

382156
type: LocalParameter
units: 304591
value: 1000.0

382154
type: LocalParameter
units: 304591
value: -1000.0

318929
type: SpeciesReference
stoichiometry: 2.0
species: 377811

378852
type: Reaction
reversible: false
reactant: 309817
kinetic law: 309866
notes: GENE_ASSOCIATION: (8574.1) or (231.1) or (10327.2) or (10327.1) SUBSYSTEM: Fructose and Mannose Metabolism
reactant: 309829
fast: false
name: D-sorbitolreductase
product: 309842
product: 309854
reactant: 309805

309817
type: SpeciesReference
stoichiometry: 1.0
species: 378077

380924
type: LocalParameter
units: 304591
value: 0.0

380921
type: LocalParameter
units: 304591
value: 0.0

380918
type: LocalParameter
units: 304591
value: 1000.0

380915
type: LocalParameter
units: 304591
value: 0.0

309829
type: SpeciesReference
stoichiometry: 1.0
species: 378236

309842
type: SpeciesReference
stoichiometry: 1.0
species: 378227

309854
type: SpeciesReference
stoichiometry: 1.0
species: 378446

378446
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Sorbitol

309805
type: SpeciesReference
stoichiometry: 1.0
species: 377951

377996
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Glycine

378215
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Nicotinamide adenine dinucleotide

378410
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Ubiquinone-10

378287
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Superoxide anion

377945
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-glucurono-6,3-lactone

377911
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Flavin adenine dinucleotide reduced

379152
type: Reaction
kinetic law: 316381
notes: GENE_ASSOCIATION: (1103.4) or (1103.2) or (1103.3) or (1103.1) SUBSYSTEM: Glycerophospholipid Metabolism
fast: false
name: CholineO-acetyltransferase
product: 316357
product: 316369
reactant: 316333
reversible: true
reactant: 316345

381824
type: LocalParameter
units: 304591
value: 0.0

381822
type: LocalParameter
units: 304591
value: 0.0

381820
type: LocalParameter
units: 304591
value: 1000.0

381818
type: LocalParameter
units: 304591
value: -1000.0

316357
type: SpeciesReference
stoichiometry: 1.0
species: 377682

316369
type: SpeciesReference
stoichiometry: 1.0
species: 377826

316333
type: SpeciesReference
stoichiometry: 1.0
species: 377673

377673
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Acetyl-CoA

316345
type: SpeciesReference
stoichiometry: 1.0
species: 377793

377793
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Choline

377778
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Bilirubin monoglucuronide

379536
type: Reaction
kinetic law: 323118
product: 323106
reactant: 323094
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: hdd2coaintracellulartransport

382735
type: LocalParameter
units: 304591
value: 0.0

382733
type: LocalParameter
units: 304591
value: 0.0

382731
type: LocalParameter
units: 304591
value: 1000.0

382729
type: LocalParameter
units: 304591
value: -1000.0

323106
type: SpeciesReference
stoichiometry: 1.0
species: 378101

323094
type: SpeciesReference
stoichiometry: 1.0
species: 378098

378098
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: trans-Hexadec-2-enoyl-CoA

378594
type: Reaction
kinetic law: 305049
product: 305037
product: 305025
reactant: 305012
notes: GENE_ASSOCIATION: SUBSYSTEM: Pyruvate Metabolism
fast: false
reversible: false
name: methylglyoxalsynthase

379970
type: LocalParameter
units: 304591
value: 0.0

379967
type: LocalParameter
units: 304591
value: 0.0

379964
type: LocalParameter
units: 304591
value: 1000.0

379961
type: LocalParameter
units: 304591
value: 0.0

305037
type: SpeciesReference
stoichiometry: 1.0
species: 378338

305025
type: SpeciesReference
stoichiometry: 1.0
species: 378200

305012
type: SpeciesReference
stoichiometry: 1.0
species: 377871

377667
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Acetaldehyde

379785
type: Reaction
kinetic law: 325900
reactant: 325888
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Serineexchange

383146
type: LocalParameter
units: 304591
value: 0.0

383145
type: LocalParameter
units: 304591
value: 0.0

383144
type: LocalParameter
units: 304591
value: 0.0

383143
type: LocalParameter
units: 304591
value: -1000.0

325888
type: SpeciesReference
stoichiometry: 1.0
species: 378458

378458
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Serine

377616
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 3-Phospho-D-glycerate

379431
type: Reaction
kinetic law: 321427
product: 321415
reactant: 321402
notes: GENE_ASSOCIATION: (2944.1) or (2944.2) SUBSYSTEM: Vitamin A Metabolism
fast: false
reversible: true
name: 13-cis-retinoicacidisomerase

382475
type: LocalParameter
units: 304591
value: 0.0

382473
type: LocalParameter
units: 304591
value: 0.0

382471
type: LocalParameter
units: 304591
value: 1000.0

382469
type: LocalParameter
units: 304591
value: -1000.0

321415
type: SpeciesReference
stoichiometry: 1.0
species: 377574

377574
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 13-cis-retinoate

321402
type: SpeciesReference
stoichiometry: 1.0
species: 378428

378831
type: Reaction
fast: false
notes: GENE_ASSOCIATION: (56848.1) SUBSYSTEM: Sphingolipid Metabolism
reactant: 309392
reactant: 309404
product: 309428
reversible: false
product: 309416
kinetic law: 309452
product: 309440

309392
type: SpeciesReference
stoichiometry: 1.0
species: 377769

309404
type: SpeciesReference
stoichiometry: 1.0
species: 378467

378467
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Sphinganine

309428
type: SpeciesReference
stoichiometry: 1.0
species: 378077

309416
type: SpeciesReference
stoichiometry: 1.0
species: 377700

380854
type: LocalParameter
units: 304591
value: 0.0

380851
type: LocalParameter
units: 304591
value: 0.0

380848
type: LocalParameter
units: 304591
value: 1000.0

380845
type: LocalParameter
units: 304591
value: 0.0

309440
type: SpeciesReference
stoichiometry: 1.0
species: 378461

378615
type: Reaction
reversible: true
product: 305365
fast: false
reactant: 305341
notes: GENE_ASSOCIATION: (7086.1) SUBSYSTEM: Pentose Phosphate Pathway
product: 305353
reactant: 305329
name: transketolase
kinetic law: 305377

305365
type: SpeciesReference
stoichiometry: 1.0
species: 378443

305341
type: SpeciesReference
stoichiometry: 1.0
species: 378551

305353
type: SpeciesReference
stoichiometry: 1.0
species: 377933

305329
type: SpeciesReference
stoichiometry: 1.0
species: 378419

380040
type: LocalParameter
units: 304591
value: 0.0

380037
type: LocalParameter
units: 304591
value: 0.0

380034
type: LocalParameter
units: 304591
value: 1000.0

380031
type: LocalParameter
units: 304591
value: 0.0

379677
type: Reaction
kinetic law: 325031
reactant: 325019
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

383002
type: LocalParameter
units: 304591
value: 0.0

383001
type: LocalParameter
units: 304591
value: 0.0

383000
type: LocalParameter
units: 304591
value: 13.5135135135135

382999
type: LocalParameter
units: 304591
value: 0.0

325019
type: SpeciesReference
stoichiometry: 1.0
species: 378092

378092
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Bicarbonate

377898
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Ethanol

377880
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Deoxyinosine

379779
type: Reaction
kinetic law: 325852
reactant: 325840
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Ureaexchange

383138
type: LocalParameter
units: 304591
value: 0.0

383137
type: LocalParameter
units: 304591
value: 0.0

383136
type: LocalParameter
units: 304591
value: 13.5135135135135

383135
type: LocalParameter
units: 304591
value: -1000.0

325840
type: SpeciesReference
stoichiometry: 1.0
species: 378533

379383
type: Reaction
kinetic law: 320498
product: 320486
reactant: 320473
notes: GENE_ASSOCIATION: SUBSYSTEM: R Group Synthesis
fast: false
reversible: false
name: Rtotalflux

382363
type: LocalParameter
units: 304591
value: 0.0

382361
type: LocalParameter
units: 304591
value: 0.0

382359
type: LocalParameter
units: 304591
value: 1000.0

382357
type: LocalParameter
units: 304591
value: 0.0

320486
type: SpeciesReference
stoichiometry: 1.0
species: 377649

320473
type: SpeciesReference
stoichiometry: 1.0
species: 377640

377640
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: R group 1 Coenzyme A homo sapiens

378254
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Ammonium

378651
type: Reaction
kinetic law: 306144
product: 306132
reactant: 306120
reactant: 306108
notes: GENE_ASSOCIATION: (203.1) SUBSYSTEM: Nucleotides
fast: false
reversible: true
name: adenylatekinase

380160
type: LocalParameter
units: 304591
value: 0.0

380157
type: LocalParameter
units: 304591
value: 0.0

380154
type: LocalParameter
units: 304591
value: 1000.0

380151
type: LocalParameter
units: 304591
value: 0.0

306132
type: SpeciesReference
stoichiometry: 2.0
species: 377700

306120
type: SpeciesReference
stoichiometry: 1.0
species: 377769

306108
type: SpeciesReference
stoichiometry: 1.0
species: 377730

378867
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Arginine and Proline Metabolism
name: L-glutamate5-semialdehydedehydratase,reversible,mitochondrial
product: 310224
fast: false
reactant: 310188
reversible: true
kinetic law: 310236
product: 310200
product: 310212

310224
type: SpeciesReference
stoichiometry: 1.0
species: 378083

310188
type: SpeciesReference
stoichiometry: 1.0
species: 377975

380974
type: LocalParameter
units: 304591
value: 0.0

380971
type: LocalParameter
units: 304591
value: 0.0

380968
type: LocalParameter
units: 304591
value: 1000.0

380965
type: LocalParameter
units: 304591
value: -1000.0

310200
type: SpeciesReference
stoichiometry: 1.0
species: 377589

377589
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: 1-Pyrroline-5-carboxylate

310212
type: SpeciesReference
stoichiometry: 1.0
species: 378065

379846
type: Reaction
kinetic law: 326407
reactant: 326395
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Glutamateexchange

383230
type: LocalParameter
units: 304591
value: 0.0

383229
type: LocalParameter
units: 304591
value: 0.0

383228
type: LocalParameter
units: 304591
value: 0.0

383227
type: LocalParameter
units: 304591
value: -1000.0

326395
type: SpeciesReference
stoichiometry: 1.0
species: 377981

377981
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Glutamate

379662
type: Reaction
kinetic law: 324911
reactant: 324899
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382982
type: LocalParameter
units: 304591
value: 0.0

382981
type: LocalParameter
units: 304591
value: 0.0

382980
type: LocalParameter
units: 304591
value: 13.5135135135135

382979
type: LocalParameter
units: 304591
value: 0.0

324899
type: SpeciesReference
stoichiometry: 1.0
species: 377748

377748
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Arginine

379362
type: Reaction
name: aldosereductase(methylglyoxal)
product: 320051
reactant: 320002
reactant: 320014
fast: false
kinetic law: 320063
reversible: false
product: 320039
reactant: 320027
notes: GENE_ASSOCIATION: (10327.2) or (8574.1) or (10327.1) or (231.1) SUBSYSTEM: Pyruvate Metabolism

320051
type: SpeciesReference
stoichiometry: 1.0
species: 378227

320002
type: SpeciesReference
stoichiometry: 1.0
species: 378077

320014
type: SpeciesReference
stoichiometry: 1.0
species: 378200

382314
type: LocalParameter
units: 304591
value: 0.0

382312
type: LocalParameter
units: 304591
value: 0.0

382310
type: LocalParameter
units: 304591
value: 1000.0

382308
type: LocalParameter
units: 304591
value: 0.0

320039
type: SpeciesReference
stoichiometry: 1.0
species: 377679

377679
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Acetol

320027
type: SpeciesReference
stoichiometry: 1.0
species: 378236

378630
type: Reaction
reactant: 305680
reversible: false
notes: GENE_ASSOCIATION: (223.1) or (224.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
kinetic law: 305740
fast: false
product: 305704
name: aldehydedehydrogenase(acetaldehyde,NADP)
product: 305716
reactant: 305668
reactant: 305692
product: 305728

305680
type: SpeciesReference
stoichiometry: 1.0
species: 378059

380090
type: LocalParameter
units: 304591
value: 0.0

380087
type: LocalParameter
units: 304591
value: 0.0

380084
type: LocalParameter
units: 304591
value: 1000.0

380081
type: LocalParameter
units: 304591
value: 0.0

305704
type: SpeciesReference
stoichiometry: 1.0
species: 377652

377652
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Acetate

305716
type: SpeciesReference
stoichiometry: 2.0
species: 378077

305668
type: SpeciesReference
stoichiometry: 1.0
species: 377661

305692
type: SpeciesReference
stoichiometry: 1.0
species: 378227

305728
type: SpeciesReference
stoichiometry: 1.0
species: 378236

379029
type: Reaction
fast: false
notes: GENE_ASSOCIATION: (4952.1) or (4952.2) SUBSYSTEM: Inositol Phosphate Metabolism
product: 313779
reactant: 313767
reversible: false
name: phosphatidylinositol-4,5-bisphosphate5-phosphatase
kinetic law: 313803
reactant: 313754
product: 313791

313779
type: SpeciesReference
stoichiometry: 1.0
species: 378314

313767
type: SpeciesReference
stoichiometry: 1.0
species: 378308

381514
type: LocalParameter
units: 304591
value: 0.0

381511
type: LocalParameter
units: 304591
value: 0.0

381508
type: LocalParameter
units: 304591
value: 1000.0

381505
type: LocalParameter
units: 304591
value: 0.0

313754
type: SpeciesReference
stoichiometry: 1.0
species: 378059

313791
type: SpeciesReference
stoichiometry: 1.0
species: 378338

379119
type: Reaction
product: 315608
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
reversible: true
reactant: 315584
fast: false
reactant: 315596
product: 315620
name: L-alanine/glutaminereversibleexchange
kinetic law: 315632

315608
type: SpeciesReference
stoichiometry: 1.0
species: 377718

377718
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Alanine

315584
type: SpeciesReference
stoichiometry: 1.0
species: 377721

315596
type: SpeciesReference
stoichiometry: 1.0
species: 377966

315620
type: SpeciesReference
stoichiometry: 1.0
species: 377969

381748
type: LocalParameter
units: 304591
value: 0.0

381746
type: LocalParameter
units: 304591
value: 0.0

381744
type: LocalParameter
units: 304591
value: 1000.0

381742
type: LocalParameter
units: 304591
value: -1000.0

378645
type: Reaction
reactant: 305976
name: L-alaninetransaminase
reversible: true
product: 306012
fast: false
kinetic law: 306024
product: 306000
reactant: 305988
notes: GENE_ASSOCIATION: (2875.1) SUBSYSTEM: Glutamate metabolism

305976
type: SpeciesReference
stoichiometry: 1.0
species: 377712

377712
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 2-Oxoglutarate

306012
type: SpeciesReference
stoichiometry: 1.0
species: 378404

380140
type: LocalParameter
units: 304591
value: 0.0

380137
type: LocalParameter
units: 304591
value: 0.0

380134
type: LocalParameter
units: 304591
value: 1000.0

380131
type: LocalParameter
units: 304591
value: -1000.0

306000
type: SpeciesReference
stoichiometry: 1.0
species: 377978

305988
type: SpeciesReference
stoichiometry: 1.0
species: 377724

377724
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Alanine

378846
type: Reaction
kinetic law: 309718
product: 309706
product: 309694
reactant: 309682
notes: GENE_ASSOCIATION: (5223.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
reversible: true
name: Diphosphoglyceromutase

380904
type: LocalParameter
units: 304591
value: 0.0

380901
type: LocalParameter
units: 304591
value: 0.0

380898
type: LocalParameter
units: 304591
value: 1000.0

380895
type: LocalParameter
units: 304591
value: -1000.0

309706
type: SpeciesReference
stoichiometry: 1.0
species: 378077

309694
type: SpeciesReference
stoichiometry: 1.0
species: 377592

377592
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 2,3-Disphospho-D-glycerate

309682
type: SpeciesReference
stoichiometry: 1.0
species: 377580

379608
type: Reaction
kinetic law: 324478
reactant: 324466
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382903
type: LocalParameter
units: 304591
value: 0.0

382901
type: LocalParameter
units: 304591
value: 0.0

382899
type: LocalParameter
units: 304591
value: 13.5135135135135

382897
type: LocalParameter
units: 304591
value: 0.0

324466
type: SpeciesReference
stoichiometry: 1.0
species: 378536

378536
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Valine

378518
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Tyrosine

379014
type: Reaction
product: 313465
reversible: false
notes: GENE_ASSOCIATION: (3939.1) or (3945.1 and 3939.1) or (3945.1) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
product: 313453
reactant: 313429
fast: false
kinetic law: 313477
reactant: 313417
product: 313441
name: glyoxylateoxidase
reactant: 313404

313465
type: SpeciesReference
stoichiometry: 1.0
species: 378299

313453
type: SpeciesReference
stoichiometry: 1.0
species: 378218

313429
type: SpeciesReference
stoichiometry: 1.0
species: 378212

381464
type: LocalParameter
units: 304591
value: 0.0

381461
type: LocalParameter
units: 304591
value: 0.0

381458
type: LocalParameter
units: 304591
value: 1000.0

381455
type: LocalParameter
units: 304591
value: 0.0

313417
type: SpeciesReference
stoichiometry: 1.0
species: 378059

313441
type: SpeciesReference
stoichiometry: 2.0
species: 378077

313404
type: SpeciesReference
stoichiometry: 1.0
species: 377987

377987
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Glyoxylate

379344
type: Reaction
kinetic law: 319761
product: 319749
reactant: 319737
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: Diphosphatetransporter,endoplasmicreticulum

382272
type: LocalParameter
units: 304591
value: 0.0

382270
type: LocalParameter
units: 304591
value: 0.0

382268
type: LocalParameter
units: 304591
value: 1000.0

382266
type: LocalParameter
units: 304591
value: -1000.0

319749
type: SpeciesReference
stoichiometry: 1.0
species: 378362

378362
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Diphosphate

319737
type: SpeciesReference
stoichiometry: 1.0
species: 378359

378693
type: Reaction
kinetic law: 306978
product: 306966
reactant: 306954
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: true
name: CO2transport(diffusion),mitochondrial

380394
type: LocalParameter
units: 304591
value: 0.0

380391
type: LocalParameter
units: 304591
value: 0.0

380388
type: LocalParameter
units: 304591
value: 1000.0

380385
type: LocalParameter
units: 304591
value: -1000.0

306966
type: SpeciesReference
stoichiometry: 1.0
species: 377823

306954
type: SpeciesReference
stoichiometry: 1.0
species: 377817

379098
type: Reaction
reactant: 315158
kinetic law: 315207
fast: false
product: 315195
reactant: 315170
reversible: true
product: 315182
name: L-Serine/Glycinereversibleexchange
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular

315158
type: SpeciesReference
stoichiometry: 1.0
species: 377993

381699
type: LocalParameter
units: 304591
value: 0.0

381697
type: LocalParameter
units: 304591
value: 0.0

381695
type: LocalParameter
units: 304591
value: 1000.0

381693
type: LocalParameter
units: 304591
value: -1000.0

315195
type: SpeciesReference
stoichiometry: 1.0
species: 378455

315170
type: SpeciesReference
stoichiometry: 1.0
species: 378458

315182
type: SpeciesReference
stoichiometry: 1.0
species: 377996

379008
type: Reaction
kinetic law: 313332
product: 313320
reactant: 313308
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: deoxyinosinetransportviadiffusion

381444
type: LocalParameter
units: 304591
value: 0.0

381441
type: LocalParameter
units: 304591
value: 0.0

381438
type: LocalParameter
units: 304591
value: 1000.0

381435
type: LocalParameter
units: 304591
value: -1000.0

313320
type: SpeciesReference
stoichiometry: 1.0
species: 377877

377877
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Deoxyinosine

313308
type: SpeciesReference
stoichiometry: 1.0
species: 377880

378377
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Proline

379575
type: Reaction
reactant: 323620
product: 323644
kinetic law: 323668
reversible: false
product: 323656
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM:
product: 323632
reactant: 323608

323620
type: SpeciesReference
stoichiometry: 1.0
species: 378059

323644
type: SpeciesReference
stoichiometry: 1.0
species: 378077

382826
type: LocalParameter
units: 304591
value: 0.0

382824
type: LocalParameter
units: 304591
value: 0.0

382822
type: LocalParameter
units: 304591
value: 1000.0

382820
type: LocalParameter
units: 304591
value: 0.0

323656
type: SpeciesReference
stoichiometry: 1.0
species: 378338

323632
type: SpeciesReference
stoichiometry: 1.0
species: 377700

323608
type: SpeciesReference
stoichiometry: 1.0
species: 377769

379323
type: Reaction
kinetic law: 319412
product: 319400
reactant: 319388
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: D-glucurono-6,3-lactonetransport,endoplasmicreticulum

382223
type: LocalParameter
units: 304591
value: 0.0

382221
type: LocalParameter
units: 304591
value: 0.0

382219
type: LocalParameter
units: 304591
value: 1000.0

382217
type: LocalParameter
units: 304591
value: -1000.0

319400
type: SpeciesReference
stoichiometry: 1.0
species: 377948

377948
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: D-glucurono-6,3-lactone

319388
type: SpeciesReference
stoichiometry: 1.0
species: 377945

379338
type: Reaction
kinetic law: 319688
product: 319676
reactant: 319664
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: false
name: NADPHtransporter,endoplasmicreticulum

382258
type: LocalParameter
units: 304591
value: 0.0

382256
type: LocalParameter
units: 304591
value: 0.0

382254
type: LocalParameter
units: 304591
value: 1000.0

382252
type: LocalParameter
units: 304591
value: 0.0

319676
type: SpeciesReference
stoichiometry: 1.0
species: 378242

319664
type: SpeciesReference
stoichiometry: 1.0
species: 378236

378735
type: Reaction
kinetic law: 307751
product: 307739
reactant: 307727
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: glyoxylatetransport,peroxisomal

380534
type: LocalParameter
units: 304591
value: 0.0

380531
type: LocalParameter
units: 304591
value: 0.0

380528
type: LocalParameter
units: 304591
value: 1000.0

380525
type: LocalParameter
units: 304591
value: -1000.0

307739
type: SpeciesReference
stoichiometry: 1.0
species: 377990

307727
type: SpeciesReference
stoichiometry: 1.0
species: 377987

378002
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Glyceraldehyde

379707
type: Reaction
kinetic law: 325274
reactant: 325261
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true

383042
type: LocalParameter
units: 304591
value: 0.0

383041
type: LocalParameter
units: 304591
value: 0.0

383040
type: LocalParameter
units: 304591
value: 13.5135135135135

383039
type: LocalParameter
units: 304591
value: 0.0

325261
type: SpeciesReference
stoichiometry: 1.0
species: 378572

378572
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546

378639
type: Reaction
kinetic law: 305902
product: 305889
product: 305876
reactant: 305863
notes: GENE_ASSOCIATION: SUBSYSTEM: Pentose Phosphate Pathway
fast: false
reversible: false
name: deoxyribose-phosphatealdolase

380120
type: LocalParameter
units: 304591
value: 0.0

380117
type: LocalParameter
units: 304591
value: 0.0

380114
type: LocalParameter
units: 304591
value: 1000.0

380111
type: LocalParameter
units: 304591
value: 0.0

305889
type: SpeciesReference
stoichiometry: 1.0
species: 377933

305876
type: SpeciesReference
stoichiometry: 1.0
species: 377661

305863
type: SpeciesReference
stoichiometry: 1.0
species: 377607

377607
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 2-Deoxy-D-ribose 5-phosphate

379239
type: Reaction
product: 317939
fast: false
kinetic law: 317951
reactant: 317903
name: oxalatetransportviabicarbonatecountertransport
notes: GENE_ASSOCIATION: (1836.1) SUBSYSTEM: Transport, Extracellular
product: 317927
reactant: 317915
reversible: false

317939
type: SpeciesReference
stoichiometry: 1.0
species: 378299

382027
type: LocalParameter
units: 304591
value: 0.0

382025
type: LocalParameter
units: 304591
value: 0.0

382023
type: LocalParameter
units: 304591
value: 1000.0

382021
type: LocalParameter
units: 304591
value: 0.0

317903
type: SpeciesReference
stoichiometry: 2.0
species: 378092

317927
type: SpeciesReference
stoichiometry: 2.0
species: 378095

378095
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Bicarbonate

317915
type: SpeciesReference
stoichiometry: 1.0
species: 378302

379569
type: Reaction
kinetic law: 323560
product: 323548
reactant: 323536
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true

382812
type: LocalParameter
units: 304591
value: 0.0

382810
type: LocalParameter
units: 304591
value: 0.0

382808
type: LocalParameter
units: 304591
value: 1000.0

382806
type: LocalParameter
units: 304591
value: -1000.0

323548
type: SpeciesReference
stoichiometry: 1.0
species: 378572

323536
type: SpeciesReference
stoichiometry: 1.0
species: 378569

378966
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Pentose and Glucuronate Interconversions
fast: false
product: 312437
name: L-gulonate3-dehydrogenase
reversible: true
product: 312449
reactant: 312413
reactant: 312401
product: 312425
kinetic law: 312461

312437
type: SpeciesReference
stoichiometry: 1.0
species: 378077

312449
type: SpeciesReference
stoichiometry: 1.0
species: 378218

312413
type: SpeciesReference
stoichiometry: 1.0
species: 378212

312401
type: SpeciesReference
stoichiometry: 1.0
species: 378038

312425
type: SpeciesReference
stoichiometry: 1.0
species: 377613

381304
type: LocalParameter
units: 304591
value: 0.0

381301
type: LocalParameter
units: 304591
value: 0.0

381298
type: LocalParameter
units: 304591
value: 1000.0

381295
type: LocalParameter
units: 304591
value: -1000.0

379077
type: Reaction
fast: false
kinetic law: 314774
notes: GENE_ASSOCIATION: (54407.1) SUBSYSTEM: Transport, Extracellular
product: 314750
product: 314762
reactant: 314726
reactant: 314738
name: L-asparaginetransportinviasodiumsymport
reversible: false

381650
type: LocalParameter
units: 304591
value: 0.0

381648
type: LocalParameter
units: 304591
value: 0.0

381646
type: LocalParameter
units: 304591
value: 1000.0

381644
type: LocalParameter
units: 304591
value: 0.0

314750
type: SpeciesReference
stoichiometry: 1.0
species: 377757

314762
type: SpeciesReference
stoichiometry: 1.0
species: 378206

314726
type: SpeciesReference
stoichiometry: 1.0
species: 377760

377760
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Asparagine

314738
type: SpeciesReference
stoichiometry: 1.0
species: 378209

377727
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Alanine

379900
type: Reaction
kinetic law: 326841
reactant: 326829
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: D-Glucoseexchange

383302
type: LocalParameter
units: 304591
value: 0.0

383301
type: LocalParameter
units: 304591
value: 0.0

383300
type: LocalParameter
units: 304591
value: 0.0

383299
type: LocalParameter
units: 304591
value: -1000.0

326829
type: SpeciesReference
stoichiometry: 1.0
species: 377954

377954
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: D-Glucose

378870
type: Reaction
name: prolineoxidase(NAD),mitochondrial
fast: false
product: 310296
reversible: false
product: 310284
product: 310272
notes: GENE_ASSOCIATION: (5625.1) SUBSYSTEM: Arginine and Proline Metabolism
reactant: 310248
reactant: 310260
kinetic law: 310308

310296
type: SpeciesReference
stoichiometry: 1.0
species: 378221

378221
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Nicotinamide adenine dinucleotide - reduced

310284
type: SpeciesReference
stoichiometry: 2.0
species: 378083

310272
type: SpeciesReference
stoichiometry: 1.0
species: 377589

310248
type: SpeciesReference
stoichiometry: 1.0
species: 378215

310260
type: SpeciesReference
stoichiometry: 1.0
species: 378383

378383
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-Proline

380984
type: LocalParameter
units: 304591
value: 0.0

380981
type: LocalParameter
units: 304591
value: 0.0

380978
type: LocalParameter
units: 304591
value: 1000.0

380975
type: LocalParameter
units: 304591
value: 0.0

379101
type: Reaction
reactant: 315219
fast: false
name: L-Serine/Glutaminereversibleexchange
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
reactant: 315231
kinetic law: 315268
reversible: true
product: 315243
product: 315255

315219
type: SpeciesReference
stoichiometry: 1.0
species: 377966

315231
type: SpeciesReference
stoichiometry: 1.0
species: 378458

381706
type: LocalParameter
units: 304591
value: 0.0

381704
type: LocalParameter
units: 304591
value: 0.0

381702
type: LocalParameter
units: 304591
value: 1000.0

381700
type: LocalParameter
units: 304591
value: -1000.0

315243
type: SpeciesReference
stoichiometry: 1.0
species: 377969

315255
type: SpeciesReference
stoichiometry: 1.0
species: 378455

379170
type: Reaction
kinetic law: 316646
product: 316634
reactant: 316622
notes: GENE_ASSOCIATION: (124935.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true

381866
type: LocalParameter
units: 304591
value: 0.0

381864
type: LocalParameter
units: 304591
value: 0.0

381862
type: LocalParameter
units: 304591
value: 1000.0

381860
type: LocalParameter
units: 304591
value: -1000.0

316634
type: SpeciesReference
stoichiometry: 1.0
species: 378188

316622
type: SpeciesReference
stoichiometry: 1.0
species: 378191

379554
type: Reaction
kinetic law: 323380
product: 323368
reactant: 323356
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: true
name: hydrogenperoxidemitochondrialtransport

382777
type: LocalParameter
units: 304591
value: 0.0

382775
type: LocalParameter
units: 304591
value: 0.0

382773
type: LocalParameter
units: 304591
value: 1000.0

382771
type: LocalParameter
units: 304591
value: -1000.0

323368
type: SpeciesReference
stoichiometry: 1.0
species: 378053

378053
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Hydrogen peroxide

323356
type: SpeciesReference
stoichiometry: 1.0
species: 378047

379548
type: Reaction
kinetic law: 323308
product: 323296
reactant: 323284
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true

382763
type: LocalParameter
units: 304591
value: 0.0

382761
type: LocalParameter
units: 304591
value: 0.0

382759
type: LocalParameter
units: 304591
value: 1000.0

382757
type: LocalParameter
units: 304591
value: -1000.0

323296
type: SpeciesReference
stoichiometry: 1.0
species: 378287

323284
type: SpeciesReference
stoichiometry: 1.0
species: 378281

379464
type: Reaction
kinetic law: 321957
product: 321945
reactant: 321933
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: false
name: urateexportfromperoxisome

382567
type: LocalParameter
units: 304591
value: 0.0

382565
type: LocalParameter
units: 304591
value: 0.0

382563
type: LocalParameter
units: 304591
value: 1000.0

382561
type: LocalParameter
units: 304591
value: 0.0

321945
type: SpeciesReference
stoichiometry: 1.0
species: 378521

378521
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Urate

321933
type: SpeciesReference
stoichiometry: 1.0
species: 378527

378527
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Urate

377685
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: Acetylcholine

378864
type: Reaction
reactant: 310139
kinetic law: 310176
reversible: true
reactant: 310151
product: 310163
notes: GENE_ASSOCIATION: SUBSYSTEM: Arginine and Proline Metabolism
reactant: 310126
fast: false
name: L-1-Pyrroline-3-hydroxy-5-carboxylatespontaneousconversiontoL-4-Hydroxyglutamatesemialdehyde,mitochondrial

310139
type: SpeciesReference
stoichiometry: 1.0
species: 378065

380964
type: LocalParameter
units: 304591
value: 0.0

380961
type: LocalParameter
units: 304591
value: 0.0

380958
type: LocalParameter
units: 304591
value: 1000.0

380955
type: LocalParameter
units: 304591
value: -1000.0

310151
type: SpeciesReference
stoichiometry: 1.0
species: 378083

310163
type: SpeciesReference
stoichiometry: 1.0
species: 377625

377625
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-4-Hydroxyglutamate semialdehyde

310126
type: SpeciesReference
stoichiometry: 1.0
species: 377586

377586
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-1-Pyrroline-3-hydroxy-5-carboxylate

378203
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Methylglyoxal

379611
type: Reaction
kinetic law: 324502
reactant: 324490
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382910
type: LocalParameter
units: 304591
value: 0.0

382908
type: LocalParameter
units: 304591
value: 0.0

382906
type: LocalParameter
units: 304591
value: 13.5135135135135

382904
type: LocalParameter
units: 304591
value: 0.0

324490
type: SpeciesReference
stoichiometry: 1.0
species: 378515

379164
type: Reaction
kinetic law: 316574
product: 316562
reactant: 316550
notes: GENE_ASSOCIATION: (124935.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true

381852
type: LocalParameter
units: 304591
value: 0.0

381850
type: LocalParameter
units: 304591
value: 0.0

381848
type: LocalParameter
units: 304591
value: 1000.0

381846
type: LocalParameter
units: 304591
value: -1000.0

316562
type: SpeciesReference
stoichiometry: 1.0
species: 378122

378122
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Isoleucine

316550
type: SpeciesReference
stoichiometry: 1.0
species: 378125

379843
type: Reaction
kinetic law: 326383
reactant: 326371
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Histidineexchange

383226
type: LocalParameter
units: 304591
value: 0.0

383225
type: LocalParameter
units: 304591
value: 0.0

383224
type: LocalParameter
units: 304591
value: 0.0

383223
type: LocalParameter
units: 304591
value: -1000.0

326371
type: SpeciesReference
stoichiometry: 1.0
species: 378107

378107
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Histidine

379191
type: Reaction
fast: false
reversible: true
product: 316984
kinetic law: 316996
product: 316972
name: D-glucosetransportinviaprotonsymport
notes: GENE_ASSOCIATION: (6524.1) SUBSYSTEM: Transport, Extracellular
reactant: 316948
reactant: 316960

316984
type: SpeciesReference
stoichiometry: 1.0
species: 378077

381915
type: LocalParameter
units: 304591
value: 0.0

381913
type: LocalParameter
units: 304591
value: 0.0

381911
type: LocalParameter
units: 304591
value: 1000.0

381909
type: LocalParameter
units: 304591
value: -1000.0

316972
type: SpeciesReference
stoichiometry: 1.0
species: 377951

316948
type: SpeciesReference
stoichiometry: 1.0
species: 377954

316960
type: SpeciesReference
stoichiometry: 1.0
species: 378080

378080
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: H+

377655
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Acetate

379797
type: Reaction
kinetic law: 325997
reactant: 325985
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Cysteineexchange

383162
type: LocalParameter
units: 304591
value: 0.0

383161
type: LocalParameter
units: 304591
value: 0.0

383160
type: LocalParameter
units: 304591
value: 0.0

383159
type: LocalParameter
units: 304591
value: -1000.0

325985
type: SpeciesReference
stoichiometry: 1.0
species: 377853

377853
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Cysteine

379395
type: Reaction
kinetic law: 320703
product: 320691
reactant: 320679
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: false

382391
type: LocalParameter
units: 304591
value: 0.0

382389
type: LocalParameter
units: 304591
value: 0.0

382387
type: LocalParameter
units: 304591
value: 1000.0

382385
type: LocalParameter
units: 304591
value: 0.0

320691
type: SpeciesReference
stoichiometry: 1.0
species: 378203

320679
type: SpeciesReference
stoichiometry: 1.0
species: 378200

379680
type: Reaction
kinetic law: 325055
reactant: 325043
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

383006
type: LocalParameter
units: 304591
value: 0.0

383005
type: LocalParameter
units: 304591
value: 0.0

383004
type: LocalParameter
units: 304591
value: 13.5135135135135

383003
type: LocalParameter
units: 304591
value: 0.0

325043
type: SpeciesReference
stoichiometry: 1.0
species: 378059

378879
type: Reaction
reversible: false
product: 310538
fast: false
reactant: 310489
name: NADHdehydrogenase,mitochondrial
notes: GENE_ASSOCIATION: (4715.1) and (4720.1) and (4719.1) and (4700.1) and (55967.1) and (4709.1) and (4710.1) and (4726.1) and (4718.1) and (4696.1) and (4694.1) and (374291.1) and (4728.1) and (4712.2) and (4717.1) and (4705.1) and (4725.1) and (4716.1) and (4537.1) and (7991.1) and (4722.1) and (4541.1) and (4539.1) and (4707.1) and (4701.1) and (4723.1) and (4698.1) and (4538.1) and (4697.1) and (51079.1) and (4714.1) and (4704.1) and (126328.1) and (4711.1) and (4724.1) and (4713.1) and (4536.1) and (4695.1) and (4702.1) and (4708.1) and (4706.1) and (4535.1) and (4731.2) and (4729.1) and (4540.1) or (4715.1) and (4720.1) and (4719.1) and (4700.1) and (55967.1) and (4709.1) and (4710.1) and (4726.1) and (4696.1) and (4718.1) and (4694.1) and (374291.1) and (4728.1) and (7991.2) and (4717.1) and (4731.1) and (4705.1) and (4725.1) and (4537.1) and (4716.1) and (4722.1) and (4541.1) and (4539.1) and (4712.1) and (4707.1) and (4701.1) and (4723.1) and (4698.1) and (4538.1) and (4697.1) and (51079.1) and (4714.1) and (4704.1) and (126328.1) and (4711.1) and (4724.1) and (4713.1) and (4536.1) and (4695.1) and (4702.1) and (4708.1) and (4535.1) and (4706.1) and (4540.1) and (4729.1) or (4715.1) and (4720.1) and (4719.1) and (4700.1) and (55967.1) and (4709.1) and (4710.1) and (4726.1) and (4718.1) and (4696.1) and (374291.1) and (4694.1) and (4728.1) and (7991.2) and (4712.2) and (4717.1) and (4705.1) and (4725.1) and (4716.1) and (4537.1) and (4722.1) and (4541.1) and (4539.1) and (4707.1) and (4701.1) and (4698.1) and (4723.1) and (4538.1) and (4697.1) and (51079.1) and (4714.1) and (4704.1) and (4711.1) and (126328.1) and (4724.1) and (4536.1) and (4713.1) and (4695.1) and (4702.1) and (4708.1) and (4731.2) and (4706.1) and (4535.1) and (4540.1) and (4729.1) or (4715.1) and (4720.1) and (4719.1) and (4700.1) and (55967.1) and (4709.1) and (4710.1) and (4726.1) and (4718.1) and (4696.1) and (374291.1) and (4694.1) and (4728.1) and (4717.1) and (4705.1) and (4725.1) and (…
reactant: 310513
product: 310550
product: 310526
kinetic law: 310562
reactant: 310501

310538
type: SpeciesReference
stoichiometry: 1.0
species: 378215

310489
type: SpeciesReference
stoichiometry: 5.0
species: 378083

310513
type: SpeciesReference
stoichiometry: 1.0
species: 378410

310550
type: SpeciesReference
stoichiometry: 1.0
species: 378413

378413
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Ubiquinol-10

310526
type: SpeciesReference
stoichiometry: 4.0
species: 378077

381014
type: LocalParameter
units: 304591
value: 0.0

381011
type: LocalParameter
units: 304591
value: 0.0

381008
type: LocalParameter
units: 304591
value: 1000.0

381005
type: LocalParameter
units: 304591
value: 0.0

310501
type: SpeciesReference
stoichiometry: 1.0
species: 378221

379695
type: Reaction
kinetic law: 325176
reactant: 325164
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

383026
type: LocalParameter
units: 304591
value: 0.0

383025
type: LocalParameter
units: 304591
value: 0.0

383024
type: LocalParameter
units: 304591
value: 13.5135135135135

383023
type: LocalParameter
units: 304591
value: 0.0

325164
type: SpeciesReference
stoichiometry: 1.0
species: 377811

379443
type: Reaction
kinetic law: 321583
product: 321571
reactant: 321559
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: 13-cis-4-oxo-retinoicacidtransport,Nuclear

382503
type: LocalParameter
units: 304591
value: 0.0

382501
type: LocalParameter
units: 304591
value: 0.0

382499
type: LocalParameter
units: 304591
value: 1000.0

382497
type: LocalParameter
units: 304591
value: -1000.0

321571
type: SpeciesReference
stoichiometry: 1.0
species: 377571

377571
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: 13-cis-oxo-retinoic acid

321559
type: SpeciesReference
stoichiometry: 1.0
species: 377568

377568
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 13-cis-oxo-retinoic acid

378843
type: Reaction
kinetic law: 309670
product: 309658
product: 309645
reactant: 309632
notes: GENE_ASSOCIATION: (847.1) SUBSYSTEM: Miscellaneous
fast: false
reversible: false
name: catalaseA,peroxisomal

380894
type: LocalParameter
units: 304591
value: 0.0

380891
type: LocalParameter
units: 304591
value: 0.0

380888
type: LocalParameter
units: 304591
value: 1000.0

380885
type: LocalParameter
units: 304591
value: 0.0

309658
type: SpeciesReference
stoichiometry: 1.0
species: 378278

309645
type: SpeciesReference
stoichiometry: 2.0
species: 378074

309632
type: SpeciesReference
stoichiometry: 2.0
species: 378056

379858
type: Reaction
kinetic law: 326503
reactant: 326491
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Arginineexchange

383246
type: LocalParameter
units: 304591
value: 0.0

383245
type: LocalParameter
units: 304591
value: 0.0

383244
type: LocalParameter
units: 304591
value: 0.0

383243
type: LocalParameter
units: 304591
value: -1000.0

326491
type: SpeciesReference
stoichiometry: 1.0
species: 377751

379891
type: Reaction
kinetic law: 326769
reactant: 326757
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: H+exchange

383290
type: LocalParameter
units: 304591
value: 0.0

383289
type: LocalParameter
units: 304591
value: 0.0

383288
type: LocalParameter
units: 304591
value: 0.0

383287
type: LocalParameter
units: 304591
value: -1000.0

326757
type: SpeciesReference
stoichiometry: 1.0
species: 378080

379689
type: Reaction
kinetic law: 325128
reactant: 325115
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

383018
type: LocalParameter
units: 304591
value: 0.0

383017
type: LocalParameter
units: 304591
value: 0.0

383016
type: LocalParameter
units: 304591
value: 13.5135135135135

383015
type: LocalParameter
units: 304591
value: 0.0

325115
type: SpeciesReference
stoichiometry: 1.0
species: 377923

379674
type: Reaction
kinetic law: 325007
reactant: 324995
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382998
type: LocalParameter
units: 304591
value: 0.0

382997
type: LocalParameter
units: 304591
value: 0.0

382996
type: LocalParameter
units: 304591
value: 13.5135135135135

382995
type: LocalParameter
units: 304591
value: 0.0

324995
type: SpeciesReference
stoichiometry: 1.0
species: 377652

378786
type: Reaction
reactant: 308570
fast: false
name: Na+/Proline-Lsymporter
product: 308595
reversible: false
reactant: 308558
kinetic law: 308607
product: 308583
notes: GENE_ASSOCIATION: (54407.1) SUBSYSTEM: Transport, Extracellular

308570
type: SpeciesReference
stoichiometry: 1.0
species: 378380

378380
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Proline

308595
type: SpeciesReference
stoichiometry: 1.0
species: 378377

308558
type: SpeciesReference
stoichiometry: 1.0
species: 378209

380704
type: LocalParameter
units: 304591
value: 0.0

380701
type: LocalParameter
units: 304591
value: 0.0

380698
type: LocalParameter
units: 304591
value: 1000.0

380695
type: LocalParameter
units: 304591
value: 0.0

308583
type: SpeciesReference
stoichiometry: 1.0
species: 378206

378627
type: Reaction
kinetic law: 305656
product: 305620
name: aldehydedehydrogenase(acetaldehyde,NAD)
notes: GENE_ASSOCIATION: (224.1) or (216.1) or (223.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
reversible: false
product: 305644
product: 305632
reactant: 305583
reactant: 305596
fast: false
reactant: 305608

380080
type: LocalParameter
units: 304591
value: 0.0

380077
type: LocalParameter
units: 304591
value: 0.0

380074
type: LocalParameter
units: 304591
value: 1000.0

380071
type: LocalParameter
units: 304591
value: 0.0

305620
type: SpeciesReference
stoichiometry: 1.0
species: 377652

305644
type: SpeciesReference
stoichiometry: 1.0
species: 378218

305632
type: SpeciesReference
stoichiometry: 2.0
species: 378077

305583
type: SpeciesReference
stoichiometry: 1.0
species: 377661

305596
type: SpeciesReference
stoichiometry: 1.0
species: 378059

305608
type: SpeciesReference
stoichiometry: 1.0
species: 378212

377835
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Coenzyme A

379374
type: Reaction
fast: false
notes: GENE_ASSOCIATION: (128.1) SUBSYSTEM: Pyruvate Metabolism
reversible: false
name: alcoholdehydrogenase(D-lactaldehyde)
reactant: 320304
product: 320340
product: 320328
product: 320316
reactant: 320292
kinetic law: 320353

320304
type: SpeciesReference
stoichiometry: 1.0
species: 378212

320340
type: SpeciesReference
stoichiometry: 1.0
species: 378218

320328
type: SpeciesReference
stoichiometry: 1.0
species: 378200

320316
type: SpeciesReference
stoichiometry: 1.0
species: 378077

320292
type: SpeciesReference
stoichiometry: 1.0
species: 378152

382342
type: LocalParameter
units: 304591
value: 0.0

382340
type: LocalParameter
units: 304591
value: 0.0

382338
type: LocalParameter
units: 304591
value: 1000.0

382336
type: LocalParameter
units: 304591
value: 0.0

379380
type: Reaction
kinetic law: 320461
product: 320449
reactant: 320437
notes: GENE_ASSOCIATION: SUBSYSTEM: R Group Synthesis
fast: false
reversible: false
name: Rgroupartificialflux

382356
type: LocalParameter
units: 304591
value: 0.0

382354
type: LocalParameter
units: 304591
value: 0.0

382352
type: LocalParameter
units: 304591
value: 1000.0

382350
type: LocalParameter
units: 304591
value: 0.0

320449
type: SpeciesReference
stoichiometry: 1.0
species: 377640

320437
type: SpeciesReference
stoichiometry: 1.0
species: 378353

378657
type: Reaction
reversible: true
kinetic law: 306264
product: 306240
fast: false
reactant: 306216
notes: GENE_ASSOCIATION: (4860.1) SUBSYSTEM: Nucleotides
product: 306252
name: purine-nucleosidephosphorylase(Adenosine)
reactant: 306228

380180
type: LocalParameter
units: 304591
value: 0.0

380177
type: LocalParameter
units: 304591
value: 0.0

380174
type: LocalParameter
units: 304591
value: 1000.0

380171
type: LocalParameter
units: 304591
value: -1000.0

306240
type: SpeciesReference
stoichiometry: 1.0
species: 377688

306216
type: SpeciesReference
stoichiometry: 1.0
species: 377694

306252
type: SpeciesReference
stoichiometry: 1.0
species: 378416

306228
type: SpeciesReference
stoichiometry: 1.0
species: 378338

378663
type: Reaction
name: purine-nucleosidephosphorylase(Deoxyguanosine)
product: 306372
kinetic law: 306384
reactant: 306336
fast: false
product: 306360
notes: GENE_ASSOCIATION: (4860.1) SUBSYSTEM: Purine Catabolism
reversible: true
reactant: 306348

306372
type: SpeciesReference
stoichiometry: 1.0
species: 378029

378029
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Guanine

380200
type: LocalParameter
units: 304591
value: 0.0

380197
type: LocalParameter
units: 304591
value: 0.0

380194
type: LocalParameter
units: 304591
value: 1000.0

380191
type: LocalParameter
units: 304591
value: -1000.0

306336
type: SpeciesReference
stoichiometry: 1.0
species: 377865

377865
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Deoxyguanosine

306360
type: SpeciesReference
stoichiometry: 1.0
species: 377604

306348
type: SpeciesReference
stoichiometry: 1.0
species: 378338

378858
type: Reaction
product: 310006
product: 310018
reactant: 309980
name: 1-pyrroline-5-carboxylatedehydrogenase,mitochondrial
kinetic law: 310030
reversible: false
reactant: 309967
notes: GENE_ASSOCIATION: (8659.1) or (8659.2) SUBSYSTEM: Glutamate metabolism
product: 309994
reactant: 309954
fast: false

310006
type: SpeciesReference
stoichiometry: 1.0
species: 378083

310018
type: SpeciesReference
stoichiometry: 1.0
species: 378221

309980
type: SpeciesReference
stoichiometry: 1.0
species: 378215

380944
type: LocalParameter
units: 304591
value: 0.0

380941
type: LocalParameter
units: 304591
value: 0.0

380938
type: LocalParameter
units: 304591
value: 1000.0

380935
type: LocalParameter
units: 304591
value: 0.0

309967
type: SpeciesReference
stoichiometry: 2.0
species: 378065

309994
type: SpeciesReference
stoichiometry: 1.0
species: 377984

309954
type: SpeciesReference
stoichiometry: 1.0
species: 377589

378500
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Threonine

379080
type: Reaction
name: L-leucinetransportinviasodiumsymport
product: 314810
product: 314822
kinetic law: 314834
reactant: 314798
fast: false
notes: GENE_ASSOCIATION: (84889.1) or (6520.1) SUBSYSTEM: Transport, Extracellular
reversible: false
reactant: 314786

314810
type: SpeciesReference
stoichiometry: 1.0
species: 378158

314822
type: SpeciesReference
stoichiometry: 1.0
species: 378206

381657
type: LocalParameter
units: 304591
value: 0.0

381655
type: LocalParameter
units: 304591
value: 0.0

381653
type: LocalParameter
units: 304591
value: 1000.0

381651
type: LocalParameter
units: 304591
value: 0.0

314798
type: SpeciesReference
stoichiometry: 1.0
species: 378209

314786
type: SpeciesReference
stoichiometry: 1.0
species: 378161

378161
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Leucine

378984
type: Reaction
reversible: false
reactant: 312837
kinetic law: 312873
product: 312861
reactant: 312813
product: 312849
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Ascorbate and Aldarate Metabolism
name: ascorbicacidoxidase
reactant: 312825

312837
type: SpeciesReference
stoichiometry: 2.0
species: 378281

381364
type: LocalParameter
units: 304591
value: 0.0

381361
type: LocalParameter
units: 304591
value: 0.0

381358
type: LocalParameter
units: 304591
value: 1000.0

381355
type: LocalParameter
units: 304591
value: 0.0

312861
type: SpeciesReference
stoichiometry: 2.0
species: 378047

312813
type: SpeciesReference
stoichiometry: 1.0
species: 377754

312849
type: SpeciesReference
stoichiometry: 1.0
species: 377874

312825
type: SpeciesReference
stoichiometry: 2.0
species: 378077

378894
type: Reaction
reversible: false
reactant: 310864
name: superoxidedismutase
product: 310877
product: 310889
reactant: 310852
kinetic law: 310901
fast: false
notes: GENE_ASSOCIATION: (6648.1) SUBSYSTEM: ROS Detoxification

310864
type: SpeciesReference
stoichiometry: 2.0
species: 378284

378284
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Superoxide anion

310877
type: SpeciesReference
stoichiometry: 1.0
species: 378053

310889
type: SpeciesReference
stoichiometry: 1.0
species: 378272

378272
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: O2

310852
type: SpeciesReference
stoichiometry: 2.0
species: 378083

381064
type: LocalParameter
units: 304591
value: 0.0

381061
type: LocalParameter
units: 304591
value: 0.0

381058
type: LocalParameter
units: 304591
value: 1000.0

381055
type: LocalParameter
units: 304591
value: 0.0

377706
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: adrenic acid

379026
type: Reaction
product: 313718
notes: GENE_ASSOCIATION: (5297.1) SUBSYSTEM: Glycerophospholipid Metabolism
fast: false
product: 313706
reactant: 313694
product: 313730
reactant: 313682
name: phosphatidylinositol4-kinase
reversible: false
kinetic law: 313743

313718
type: SpeciesReference
stoichiometry: 1.0
species: 378077

313706
type: SpeciesReference
stoichiometry: 1.0
species: 377700

313694
type: SpeciesReference
stoichiometry: 1.0
species: 378323

378323
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: phosphatidylinositol (homo sapiens)

313730
type: SpeciesReference
stoichiometry: 1.0
species: 378314

313682
type: SpeciesReference
stoichiometry: 1.0
species: 377769

381504
type: LocalParameter
units: 304591
value: 0.0

381501
type: LocalParameter
units: 304591
value: 0.0

381498
type: LocalParameter
units: 304591
value: 1000.0

381495
type: LocalParameter
units: 304591
value: 0.0

379710
type: Reaction
kinetic law: 325298
reactant: 325286
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true

383046
type: LocalParameter
units: 304591
value: 0.0

383045
type: LocalParameter
units: 304591
value: 0.0

383044
type: LocalParameter
units: 304591
value: 0.0

383043
type: LocalParameter
units: 304591
value: -1000.0

325286
type: SpeciesReference
stoichiometry: 1.0
species: 378575

378575
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546

378642
type: Reaction
notes: GENE_ASSOCIATION: (2805.1) SUBSYSTEM: Alanine and Aspartate Metabolism
reversible: true
reactant: 305928
fast: false
product: 305940
kinetic law: 305964
name: aspartatetransaminase
product: 305952
reactant: 305915

305928
type: SpeciesReference
stoichiometry: 1.0
species: 377763

377763
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Aspartate

305940
type: SpeciesReference
stoichiometry: 1.0
species: 377978

380130
type: LocalParameter
units: 304591
value: 0.0

380127
type: LocalParameter
units: 304591
value: 0.0

380124
type: LocalParameter
units: 304591
value: 0.0

380121
type: LocalParameter
units: 304591
value: -1000.0

305952
type: SpeciesReference
stoichiometry: 1.0
species: 378290

305915
type: SpeciesReference
stoichiometry: 1.0
species: 377712

378747
type: Reaction
product: 307920
kinetic law: 307944
product: 307932
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
reactant: 307908
reactant: 307896
reversible: true
name: acetatereversibletransportviaprotonsymport
fast: false

307920
type: SpeciesReference
stoichiometry: 1.0
species: 377652

380574
type: LocalParameter
units: 304591
value: 0.0

380571
type: LocalParameter
units: 304591
value: 0.0

380568
type: LocalParameter
units: 304591
value: 1000.0

380565
type: LocalParameter
units: 304591
value: 0.0

307932
type: SpeciesReference
stoichiometry: 1.0
species: 378077

307908
type: SpeciesReference
stoichiometry: 1.0
species: 378080

307896
type: SpeciesReference
stoichiometry: 1.0
species: 377655

379725
type: Reaction
kinetic law: 325419
reactant: 325407
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Urateexchange

383066
type: LocalParameter
units: 304591
value: 0.0

383065
type: LocalParameter
units: 304591
value: 0.0

383064
type: LocalParameter
units: 304591
value: 13.5135135135135

383063
type: LocalParameter
units: 304591
value: 0.0

325407
type: SpeciesReference
stoichiometry: 1.0
species: 378524

378524
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Urate

379503
type: Reaction
kinetic law: 322552
product: 322540
reactant: 322528
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: phosphatidylinositol4-phosphatenucleartransport(diffusion)

382658
type: LocalParameter
units: 304591
value: 0.0

382656
type: LocalParameter
units: 304591
value: 0.0

382654
type: LocalParameter
units: 304591
value: 1000.0

382652
type: LocalParameter
units: 304591
value: -1000.0

322540
type: SpeciesReference
stoichiometry: 1.0
species: 378317

322528
type: SpeciesReference
stoichiometry: 1.0
species: 378314

378915
type: Reaction
kinetic law: 311360
product: 311348
reactant: 311287
fast: false
reactant: 311275
product: 311323
product: 311311
reactant: 311299
reversible: true
notes: GENE_ASSOCIATION: (2746.1) SUBSYSTEM: Glutamate metabolism
product: 311336

381134
type: LocalParameter
units: 304591
value: 0.0

381131
type: LocalParameter
units: 304591
value: 0.0

381128
type: LocalParameter
units: 304591
value: 1000.0

381125
type: LocalParameter
units: 304591
value: -1000.0

311348
type: SpeciesReference
stoichiometry: 1.0
species: 378251

311287
type: SpeciesReference
stoichiometry: 1.0
species: 378065

311275
type: SpeciesReference
stoichiometry: 1.0
species: 377984

311323
type: SpeciesReference
stoichiometry: 1.0
species: 378083

311311
type: SpeciesReference
stoichiometry: 1.0
species: 377715

311299
type: SpeciesReference
stoichiometry: 1.0
species: 378215

311336
type: SpeciesReference
stoichiometry: 1.0
species: 378221

379341
type: Reaction
kinetic law: 319725
product: 319712
reactant: 319700
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: false
name: NADPtransporter,endoplasmicreticulum

382265
type: LocalParameter
units: 304591
value: 0.0

382263
type: LocalParameter
units: 304591
value: 0.0

382261
type: LocalParameter
units: 304591
value: 1000.0

382259
type: LocalParameter
units: 304591
value: 0.0

319712
type: SpeciesReference
stoichiometry: 1.0
species: 378227

319700
type: SpeciesReference
stoichiometry: 1.0
species: 378233

379089
type: Reaction
reactant: 314954
notes: GENE_ASSOCIATION: (54407.1) SUBSYSTEM: Transport, Extracellular
reversible: false
fast: false
reactant: 314942
kinetic law: 314990
product: 314966
product: 314978
name: L-histidinetransportinviasodiumsymport

314954
type: SpeciesReference
stoichiometry: 1.0
species: 378209

314942
type: SpeciesReference
stoichiometry: 1.0
species: 378107

381678
type: LocalParameter
units: 304591
value: 0.0

381676
type: LocalParameter
units: 304591
value: 0.0

381674
type: LocalParameter
units: 304591
value: 1000.0

381672
type: LocalParameter
units: 304591
value: 0.0

314966
type: SpeciesReference
stoichiometry: 1.0
species: 378104

378104
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Histidine

314978
type: SpeciesReference
stoichiometry: 1.0
species: 378206

377963
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: D-Glucuronate

378999
type: Reaction
product: 313198
notes: GENE_ASSOCIATION: SUBSYSTEM: Ascorbate and Aldarate Metabolism
reactant: 313186
reactant: 313174
product: 313210
name: uronolactonase,endoplasmicreticulum
reversible: true
fast: false
kinetic law: 313222

313198
type: SpeciesReference
stoichiometry: 1.0
species: 377948

313186
type: SpeciesReference
stoichiometry: 1.0
species: 378086

313174
type: SpeciesReference
stoichiometry: 1.0
species: 377963

313210
type: SpeciesReference
stoichiometry: 1.0
species: 378071

381414
type: LocalParameter
units: 304591
value: 0.0

381411
type: LocalParameter
units: 304591
value: 0.0

381408
type: LocalParameter
units: 304591
value: 1000.0

381405
type: LocalParameter
units: 304591
value: -1000.0

377796
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Choline

378473
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Sphingosine

379413
type: Reaction
product: 321111
reversible: true
reactant: 321075
product: 321099
kinetic law: 321135
product: 321123
name: retinaldehydrogenase(NADPH)
reactant: 321087
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
reactant: 321063

321111
type: SpeciesReference
stoichiometry: 1.0
species: 378236

321075
type: SpeciesReference
stoichiometry: 1.0
species: 378227

321099
type: SpeciesReference
stoichiometry: 2.0
species: 378077

382433
type: LocalParameter
units: 304591
value: 0.0

382431
type: LocalParameter
units: 304591
value: 0.0

382429
type: LocalParameter
units: 304591
value: 1000.0

382427
type: LocalParameter
units: 304591
value: -1000.0

321123
type: SpeciesReference
stoichiometry: 1.0
species: 378428

321087
type: SpeciesReference
stoichiometry: 1.0
species: 378425

378425
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Retinal

321063
type: SpeciesReference
stoichiometry: 1.0
species: 378059

378909
type: Reaction
product: 311191
product: 311179
fast: false
reactant: 311166
notes: GENE_ASSOCIATION: (6569.1) SUBSYSTEM: Transport, Extracellular
reactant: 311154
reversible: true
kinetic law: 311203
name: phosphatetransportin/outviathreeNa+symporter

311191
type: SpeciesReference
stoichiometry: 1.0
species: 378338

311179
type: SpeciesReference
stoichiometry: 3.0
species: 378206

311166
type: SpeciesReference
stoichiometry: 1.0
species: 378341

311154
type: SpeciesReference
stoichiometry: 3.0
species: 378209

381114
type: LocalParameter
units: 304591
value: 0.0

381111
type: LocalParameter
units: 304591
value: 0.0

381108
type: LocalParameter
units: 304591
value: 1000.0

381105
type: LocalParameter
units: 304591
value: 0.0

377634
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Cystine

379587
type: Reaction
kinetic law: 324310
reactant: 324298
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382854
type: LocalParameter
units: 304591
value: 0.0

382852
type: LocalParameter
units: 304591
value: 0.0

382850
type: LocalParameter
units: 304591
value: 13.5135135135135

382848
type: LocalParameter
units: 304591
value: 0.0

324298
type: SpeciesReference
stoichiometry: 1.0
species: 378521

379335
type: Reaction
kinetic law: 319652
product: 319640
reactant: 319628
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: Htransporter,endoplasmicreticulum

382251
type: LocalParameter
units: 304591
value: 0.0

382249
type: LocalParameter
units: 304591
value: 0.0

382247
type: LocalParameter
units: 304591
value: 1000.0

382245
type: LocalParameter
units: 304591
value: -1000.0

319640
type: SpeciesReference
stoichiometry: 1.0
species: 378086

319628
type: SpeciesReference
stoichiometry: 1.0
species: 378077

378119
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Isocitrate

379113
type: Reaction
reactant: 315475
name: L-alanine/glutaminereversibleexchange
fast: false
reactant: 315463
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
kinetic law: 315511
reversible: true
product: 315499
product: 315487

315475
type: SpeciesReference
stoichiometry: 1.0
species: 377966

315463
type: SpeciesReference
stoichiometry: 1.0
species: 377727

381734
type: LocalParameter
units: 304591
value: 0.0

381732
type: LocalParameter
units: 304591
value: 0.0

381730
type: LocalParameter
units: 304591
value: 1000.0

381728
type: LocalParameter
units: 304591
value: -1000.0

315499
type: SpeciesReference
stoichiometry: 1.0
species: 377969

315487
type: SpeciesReference
stoichiometry: 1.0
species: 377724

379704
type: Reaction
kinetic law: 325249
reactant: 325237
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true

383038
type: LocalParameter
units: 304591
value: 0.0

383037
type: LocalParameter
units: 304591
value: 0.0

383036
type: LocalParameter
units: 304591
value: 13.5135135135135

383035
type: LocalParameter
units: 304591
value: 0.0

325237
type: SpeciesReference
stoichiometry: 1.0
species: 378566

379719
type: Reaction
kinetic law: 325371
reactant: 325359
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
name: 13-cis-retinoatedemand

383058
type: LocalParameter
units: 304591
value: 0.0

383057
type: LocalParameter
units: 304591
value: 0.0

383056
type: LocalParameter
units: 304591
value: 13.5135135135135

383055
type: LocalParameter
units: 304591
value: 0.0

325359
type: SpeciesReference
stoichiometry: 1.0
species: 377577

377577
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: 13-cis-retinoate

379566
type: Reaction
kinetic law: 323524
product: 323512
reactant: 323500
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true

382805
type: LocalParameter
units: 304591
value: 0.0

382803
type: LocalParameter
units: 304591
value: 0.0

382801
type: LocalParameter
units: 304591
value: 1000.0

382799
type: LocalParameter
units: 304591
value: -1000.0

323512
type: SpeciesReference
stoichiometry: 1.0
species: 378569

323500
type: SpeciesReference
stoichiometry: 1.0
species: 377583

377583
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: 1-alpha,25-Dihydroxyvitamin D3

378978
type: Reaction
kinetic law: 312740
product: 312716
notes: GENE_ASSOCIATION: SUBSYSTEM: Pentose and Glucuronate Interconversions
fast: false
reactant: 312679
reactant: 312692
reversible: true
reactant: 312704
name: gulonatedehydrogenase,endoplasmicreticulum
product: 312728

381344
type: LocalParameter
units: 304591
value: 0.0

381341
type: LocalParameter
units: 304591
value: 0.0

381338
type: LocalParameter
units: 304591
value: 1000.0

381335
type: LocalParameter
units: 304591
value: -1000.0

312716
type: SpeciesReference
stoichiometry: 1.0
species: 378041

378041
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: L-Gulonate

312679
type: SpeciesReference
stoichiometry: 1.0
species: 377963

312692
type: SpeciesReference
stoichiometry: 1.0
species: 378086

312704
type: SpeciesReference
stoichiometry: 1.0
species: 378242

312728
type: SpeciesReference
stoichiometry: 1.0
species: 378233

377904
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Fructose 1-phosphate

378497
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 5,6,7,8-Tetrahydrofolate

378588
type: Reaction
reactant: 304867
product: 304915
kinetic law: 304927
fast: false
reactant: 304879
reversible: false
notes: GENE_ASSOCIATION: (5315.2) or (5315.1) or (5315.3) SUBSYSTEM: Glycolysis/Gluconeogenesis
product: 304903
reactant: 304891
name: pyruvatekinase

304867
type: SpeciesReference
stoichiometry: 1.0
species: 377700

304915
type: SpeciesReference
stoichiometry: 1.0
species: 378404

379950
type: LocalParameter
units: 304591
value: 0.0

379947
type: LocalParameter
units: 304591
value: 0.0

379944
type: LocalParameter
units: 304591
value: 1000.0

379941
type: LocalParameter
units: 304591
value: 0.0

304879
type: SpeciesReference
stoichiometry: 1.0
species: 378077

304903
type: SpeciesReference
stoichiometry: 1.0
species: 377769

304891
type: SpeciesReference
stoichiometry: 1.0
species: 378329

378876
type: Reaction
notes: GENE_ASSOCIATION: (4967.1) and (1738.1 and 8050.1) and (1743.1) or (4967.2) and (1738.1 and 8050.1) and (1743.1) SUBSYSTEM: Citric Acid Cycle
reactant: 310417
fast: false
product: 310453
reactant: 310429
product: 310465
name: 2-oxoglutaratedehydrogenase
reversible: false
product: 310441
kinetic law: 310477
reactant: 310405

310417
type: SpeciesReference
stoichiometry: 1.0
species: 377829

310453
type: SpeciesReference
stoichiometry: 1.0
species: 378221

310429
type: SpeciesReference
stoichiometry: 1.0
species: 378215

310465
type: SpeciesReference
stoichiometry: 1.0
species: 378494

310441
type: SpeciesReference
stoichiometry: 1.0
species: 377823

381004
type: LocalParameter
units: 304591
value: 0.0

381001
type: LocalParameter
units: 304591
value: 0.0

380998
type: LocalParameter
units: 304591
value: 1000.0

380995
type: LocalParameter
units: 304591
value: 0.0

310405
type: SpeciesReference
stoichiometry: 1.0
species: 377715

378882
type: Reaction
reactant: 310586
product: 310598
name: alpha-ketoglutarate/malatetransporter
kinetic law: 310622
product: 310610
reactant: 310574
reversible: true
notes: GENE_ASSOCIATION: (8402.1) SUBSYSTEM: Transport, Mitochondrial
fast: false

310586
type: SpeciesReference
stoichiometry: 1.0
species: 378182

310598
type: SpeciesReference
stoichiometry: 1.0
species: 377712

381024
type: LocalParameter
units: 304591
value: 0.0

381021
type: LocalParameter
units: 304591
value: 0.0

381018
type: LocalParameter
units: 304591
value: 0.0

381015
type: LocalParameter
units: 304591
value: -1000.0

310610
type: SpeciesReference
stoichiometry: 1.0
species: 378185

310574
type: SpeciesReference
stoichiometry: 1.0
species: 377715

379176
type: Reaction
kinetic law: 316719
product: 316707
reactant: 316695
notes: GENE_ASSOCIATION: (124935.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true

381880
type: LocalParameter
units: 304591
value: 0.0

381878
type: LocalParameter
units: 304591
value: 0.0

381876
type: LocalParameter
units: 304591
value: 1000.0

381874
type: LocalParameter
units: 304591
value: -1000.0

316707
type: SpeciesReference
stoichiometry: 1.0
species: 377850

377850
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Cysteine

316695
type: SpeciesReference
stoichiometry: 1.0
species: 377853

379182
type: Reaction
product: 316815
kinetic law: 316839
reactant: 316791
notes: GENE_ASSOCIATION: (6584.1) SUBSYSTEM: Transport, Extracellular
reactant: 316803
name: L-lysinetransportinviasodiumsymport
fast: false
reversible: false
product: 316827

316815
type: SpeciesReference
stoichiometry: 1.0
species: 378173

381894
type: LocalParameter
units: 304591
value: 0.0

381892
type: LocalParameter
units: 304591
value: 0.0

381890
type: LocalParameter
units: 304591
value: 1000.0

381888
type: LocalParameter
units: 304591
value: 0.0

316791
type: SpeciesReference
stoichiometry: 1.0
species: 378176

316803
type: SpeciesReference
stoichiometry: 1.0
species: 378209

316827
type: SpeciesReference
stoichiometry: 1.0
species: 378206

379644
type: Reaction
kinetic law: 324767
reactant: 324755
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382958
type: LocalParameter
units: 304591
value: 0.0

382957
type: LocalParameter
units: 304591
value: 0.0

382956
type: LocalParameter
units: 304591
value: 13.5135135135135

382955
type: LocalParameter
units: 304591
value: 0.0

324755
type: SpeciesReference
stoichiometry: 1.0
species: 377993

379861
type: Reaction
kinetic law: 326527
reactant: 326515
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Alanineexchange

383250
type: LocalParameter
units: 304591
value: 0.0

383249
type: LocalParameter
units: 304591
value: 0.0

383248
type: LocalParameter
units: 304591
value: 0.0

383247
type: LocalParameter
units: 304591
value: -1000.0

326515
type: SpeciesReference
stoichiometry: 1.0
species: 377727

379855
type: Reaction
kinetic law: 326479
reactant: 326467
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Asparagineexchange

383242
type: LocalParameter
units: 304591
value: 0.0

383241
type: LocalParameter
units: 304591
value: 0.0

383240
type: LocalParameter
units: 304591
value: 0.0

383239
type: LocalParameter
units: 304591
value: -1000.0

326467
type: SpeciesReference
stoichiometry: 1.0
species: 377760

379461
type: Reaction
kinetic law: 321921
product: 321909
reactant: 321897
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: fattyacidintracellulartransport

382560
type: LocalParameter
units: 304591
value: 0.0

382558
type: LocalParameter
units: 304591
value: 0.0

382556
type: LocalParameter
units: 304591
value: 1000.0

382554
type: LocalParameter
units: 304591
value: -1000.0

321909
type: SpeciesReference
stoichiometry: 1.0
species: 378356

321897
type: SpeciesReference
stoichiometry: 1.0
species: 378353

379476
type: Reaction
kinetic law: 322128
product: 322116
reactant: 322104
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: false
name: oxalatetransportoutofperoxisome

382595
type: LocalParameter
units: 304591
value: 0.0

382593
type: LocalParameter
units: 304591
value: 0.0

382591
type: LocalParameter
units: 304591
value: 1000.0

382589
type: LocalParameter
units: 304591
value: 0.0

322116
type: SpeciesReference
stoichiometry: 1.0
species: 378299

322104
type: SpeciesReference
stoichiometry: 1.0
species: 378305

379455
type: Reaction
product: 321776
reactant: 321704
product: 321752
name: ProstaglandinG/Hsynthase
kinetic law: 321788
reactant: 321740
product: 321764
notes: GENE_ASSOCIATION: (5743.1) SUBSYSTEM: Eicosanoid Metabolism
reversible: false
fast: false
reactant: 321716
reactant: 321728

321776
type: SpeciesReference
stoichiometry: 1.0
species: 378389

321704
type: SpeciesReference
stoichiometry: 1.0
species: 377739

321752
type: SpeciesReference
stoichiometry: 1.0
species: 378059

382546
type: LocalParameter
units: 304591
value: 0.0

382544
type: LocalParameter
units: 304591
value: 0.0

382542
type: LocalParameter
units: 304591
value: 1000.0

382540
type: LocalParameter
units: 304591
value: 0.0

321740
type: SpeciesReference
stoichiometry: 2.0
species: 378266

321764
type: SpeciesReference
stoichiometry: 1.0
species: 378227

321716
type: SpeciesReference
stoichiometry: 1.0
species: 378077

321728
type: SpeciesReference
stoichiometry: 1.0
species: 378236

378855
type: Reaction
kinetic law: 309941
fast: false
product: 309928
product: 309915
reactant: 309902
reactant: 309878
notes: GENE_ASSOCIATION: (9615.1) SUBSYSTEM: Purine Catabolism
name: guaninedeaminase
reversible: false
reactant: 309890

380934
type: LocalParameter
units: 304591
value: 0.0

380931
type: LocalParameter
units: 304591
value: 0.0

380928
type: LocalParameter
units: 304591
value: 1000.0

380925
type: LocalParameter
units: 304591
value: 0.0

309928
type: SpeciesReference
stoichiometry: 1.0
species: 378542

378542
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Xanthine

309915
type: SpeciesReference
stoichiometry: 1.0
species: 378245

309902
type: SpeciesReference
stoichiometry: 1.0
species: 378077

309878
type: SpeciesReference
stoichiometry: 1.0
species: 378029

309890
type: SpeciesReference
stoichiometry: 1.0
species: 378059

378861
type: Reaction
fast: false
product: 310090
reactant: 310042
notes: GENE_ASSOCIATION: (8659.1) or (8659.2) SUBSYSTEM: Arginine and Proline Metabolism
reversible: false
name: L-1-pyrroline-3-hydroxy-5-carboxylatedehydrogenase
product: 310102
product: 310078
kinetic law: 310114
reactant: 310054
reactant: 310066

310090
type: SpeciesReference
stoichiometry: 1.0
species: 378083

310042
type: SpeciesReference
stoichiometry: 1.0
species: 377586

310102
type: SpeciesReference
stoichiometry: 1.0
species: 378221

310078
type: SpeciesReference
stoichiometry: 1.0
species: 377889

377889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-erythro-4-Hydroxyglutamate

380954
type: LocalParameter
units: 304591
value: 0.0

380951
type: LocalParameter
units: 304591
value: 0.0

380948
type: LocalParameter
units: 304591
value: 1000.0

380945
type: LocalParameter
units: 304591
value: 0.0

310054
type: SpeciesReference
stoichiometry: 2.0
species: 378065

310066
type: SpeciesReference
stoichiometry: 1.0
species: 378215

379161
type: Reaction
kinetic law: 316538
product: 316525
reactant: 316513
notes: GENE_ASSOCIATION: (124935.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true

381845
type: LocalParameter
units: 304591
value: 0.0

381843
type: LocalParameter
units: 304591
value: 0.0

381841
type: LocalParameter
units: 304591
value: 1000.0

381839
type: LocalParameter
units: 304591
value: -1000.0

316525
type: SpeciesReference
stoichiometry: 1.0
species: 378158

316513
type: SpeciesReference
stoichiometry: 1.0
species: 378161

379623
type: Reaction
kinetic law: 324598
reactant: 324586
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382929
type: LocalParameter
units: 304591
value: 0.0

382928
type: LocalParameter
units: 304591
value: 0.0

382927
type: LocalParameter
units: 304591
value: 13.5135135135135

382926
type: LocalParameter
units: 304591
value: 0.0

324586
type: SpeciesReference
stoichiometry: 1.0
species: 378377

379840
type: Reaction
kinetic law: 326359
reactant: 326346
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Isoleucineexchange

383222
type: LocalParameter
units: 304591
value: 0.0

383221
type: LocalParameter
units: 304591
value: 0.0

383220
type: LocalParameter
units: 304591
value: 0.0

383219
type: LocalParameter
units: 304591
value: -1000.0

326346
type: SpeciesReference
stoichiometry: 1.0
species: 378125

379407
type: Reaction
kinetic law: 320967
product: 320955
reactant: 320943
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: pristcoaperoxisomaltransport

382419
type: LocalParameter
units: 304591
value: 0.0

382417
type: LocalParameter
units: 304591
value: 0.0

382415
type: LocalParameter
units: 304591
value: 1000.0

382413
type: LocalParameter
units: 304591
value: -1000.0

320955
type: SpeciesReference
stoichiometry: 1.0
species: 378371

378371
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: pristanoyl coa

320943
type: SpeciesReference
stoichiometry: 1.0
species: 378374

378374
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: pristanoyl coa

379392
type: Reaction
kinetic law: 320667
reversible: false
product: 320643
name: lipase
reactant: 320619
fast: false
product: 320655
product: 320631
notes: GENE_ASSOCIATION: (4023.1) SUBSYSTEM: Triacylglycerol Synthesis
reactant: 320607

382384
type: LocalParameter
units: 304591
value: 0.0

382382
type: LocalParameter
units: 304591
value: 0.0

382380
type: LocalParameter
units: 304591
value: 1000.0

382378
type: LocalParameter
units: 304591
value: 0.0

320643
type: SpeciesReference
stoichiometry: 1.0
species: 378077

320619
type: SpeciesReference
stoichiometry: 1.0
species: 378059

320655
type: SpeciesReference
stoichiometry: 1.0
species: 378179

320631
type: SpeciesReference
stoichiometry: 1.0
species: 377646

320607
type: SpeciesReference
stoichiometry: 1.0
species: 377862

378197
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 5,10-Methylenetetrahydrofolate

378807
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
product: 309042
name: acetatemitochondrialtransportviaprotonsymport
fast: false
reactant: 309018
reversible: true
reactant: 309006
kinetic law: 309054
product: 309030

309042
type: SpeciesReference
stoichiometry: 1.0
species: 378083

309018
type: SpeciesReference
stoichiometry: 1.0
species: 378077

309006
type: SpeciesReference
stoichiometry: 1.0
species: 377652

380774
type: LocalParameter
units: 304591
value: 0.0

380771
type: LocalParameter
units: 304591
value: 0.0

380768
type: LocalParameter
units: 304591
value: 1000.0

380765
type: LocalParameter
units: 304591
value: -1000.0

309030
type: SpeciesReference
stoichiometry: 1.0
species: 377658

377658
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Acetate

379071
type: Reaction
kinetic law: 314678
product: 314666
reactant: 314653
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: false

381636
type: LocalParameter
units: 304591
value: 0.0

381634
type: LocalParameter
units: 304591
value: 0.0

381632
type: LocalParameter
units: 304591
value: 1000.0

381630
type: LocalParameter
units: 304591
value: 0.0

314666
type: SpeciesReference
stoichiometry: 1.0
species: 377601

377601
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: 25-Hydroxyvitamin D3

314653
type: SpeciesReference
stoichiometry: 1.0
species: 377595

378675
type: Reaction
product: 306639
fast: false
reactant: 306590
name: nicotinate-nucleotideadenylyltransferase
product: 306627
kinetic law: 306651
reversible: false
reactant: 306614
notes: GENE_ASSOCIATION: (5168.1) SUBSYSTEM: NAD Metabolism
reactant: 306602

306639
type: SpeciesReference
stoichiometry: 1.0
species: 378359

306590
type: SpeciesReference
stoichiometry: 1.0
species: 377769

306627
type: SpeciesReference
stoichiometry: 1.0
species: 377883

377883
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Deamino-NAD+

380334
type: LocalParameter
units: 304591
value: 0.0

380331
type: LocalParameter
units: 304591
value: 0.0

380328
type: LocalParameter
units: 304591
value: 1000.0

380325
type: LocalParameter
units: 304591
value: 0.0

306614
type: SpeciesReference
stoichiometry: 1.0
species: 378257

378257
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Nicotinate D-ribonucleotide

306602
type: SpeciesReference
stoichiometry: 1.0
species: 378077

379692
type: Reaction
kinetic law: 325152
reactant: 325140
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

383022
type: LocalParameter
units: 304591
value: 0.0

383021
type: LocalParameter
units: 304591
value: 0.0

383020
type: LocalParameter
units: 304591
value: 13.5135135135135

383019
type: LocalParameter
units: 304591
value: 0.0

325140
type: SpeciesReference
stoichiometry: 1.0
species: 378140

379233
type: Reaction
product: 317818
reactant: 317793
reactant: 317781
name: L-carnitineinwardtransportbyNa+symport
kinetic law: 317831
reversible: false
fast: false
product: 317806
notes: GENE_ASSOCIATION: (6584.1) SUBSYSTEM: Transport, Extracellular

317818
type: SpeciesReference
stoichiometry: 1.0
species: 378206

317793
type: SpeciesReference
stoichiometry: 1.0
species: 378209

317781
type: SpeciesReference
stoichiometry: 1.0
species: 377841

382013
type: LocalParameter
units: 304591
value: 0.0

382011
type: LocalParameter
units: 304591
value: 0.0

382009
type: LocalParameter
units: 304591
value: 1000.0

382007
type: LocalParameter
units: 304591
value: 0.0

317806
type: SpeciesReference
stoichiometry: 1.0
species: 377838

378702
type: Reaction
kinetic law: 307135
product: 307123
reactant: 307111
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: true
name: O2transport(diffusion)

380424
type: LocalParameter
units: 304591
value: 0.0

380421
type: LocalParameter
units: 304591
value: 0.0

380418
type: LocalParameter
units: 304591
value: 1000.0

380415
type: LocalParameter
units: 304591
value: -1000.0

307123
type: SpeciesReference
stoichiometry: 1.0
species: 378272

307111
type: SpeciesReference
stoichiometry: 1.0
species: 378266

379305
type: Reaction
kinetic law: 319074
product: 319062
reactant: 319049
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: false
name: L-gulonateendoplasmicreticularexport

382181
type: LocalParameter
units: 304591
value: 0.0

382179
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units: 304591
value: 0.0

382177
type: LocalParameter
units: 304591
value: 1000.0

382175
type: LocalParameter
units: 304591
value: 0.0

319062
type: SpeciesReference
stoichiometry: 1.0
species: 378038

319049
type: SpeciesReference
stoichiometry: 1.0
species: 378041

378717
type: Reaction
reactant: 307353
name: lactaldehydedehydrogenase
kinetic law: 307426
reactant: 307365
product: 307401
reversible: false
product: 307414
product: 307389
notes: GENE_ASSOCIATION: (223.1) or (224.1) or (216.1) SUBSYSTEM: Pyruvate Metabolism
reactant: 307377
fast: false

307353
type: SpeciesReference
stoichiometry: 1.0
species: 378059

380474
type: LocalParameter
units: 304591
value: 0.0

380471
type: LocalParameter
units: 304591
value: 0.0

380468
type: LocalParameter
units: 304591
value: 1000.0

380465
type: LocalParameter
units: 304591
value: 0.0

307365
type: SpeciesReference
stoichiometry: 1.0
species: 378155

378155
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Lactaldehyde

307401
type: SpeciesReference
stoichiometry: 1.0
species: 378146

307414
type: SpeciesReference
stoichiometry: 1.0
species: 378218

307389
type: SpeciesReference
stoichiometry: 2.0
species: 378077

307377
type: SpeciesReference
stoichiometry: 1.0
species: 378212

377775
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Bilirubin monoglucuronide

379686
type: Reaction
kinetic law: 325103
reactant: 325091
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

383014
type: LocalParameter
units: 304591
value: 0.0

383013
type: LocalParameter
units: 304591
value: 0.0

383012
type: LocalParameter
units: 304591
value: 13.5135135135135

383011
type: LocalParameter
units: 304591
value: 0.0

325091
type: SpeciesReference
stoichiometry: 1.0
species: 378299

378798
type: Reaction
name: Glycolaldehydedehydrogenase
fast: false
product: 308836
reversible: false
notes: GENE_ASSOCIATION: (223.1) or (224.1) or (216.1) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
kinetic law: 308849
product: 308824
reactant: 308775
product: 308812
reactant: 308787
reactant: 308800

308836
type: SpeciesReference
stoichiometry: 1.0
species: 378218

380744
type: LocalParameter
units: 304591
value: 0.0

380741
type: LocalParameter
units: 304591
value: 0.0

380738
type: LocalParameter
units: 304591
value: 1000.0

380735
type: LocalParameter
units: 304591
value: 0.0

308824
type: SpeciesReference
stoichiometry: 2.0
species: 378077

308775
type: SpeciesReference
stoichiometry: 1.0
species: 377936

308812
type: SpeciesReference
stoichiometry: 1.0
species: 378005

308787
type: SpeciesReference
stoichiometry: 1.0
species: 378059

308800
type: SpeciesReference
stoichiometry: 1.0
species: 378212

378750
type: Reaction
kinetic law: 307980
product: 307968
reactant: 307956
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: ethanolreversibletransport

380584
type: LocalParameter
units: 304591
value: 0.0

380581
type: LocalParameter
units: 304591
value: 0.0

380578
type: LocalParameter
units: 304591
value: 1000.0

380575
type: LocalParameter
units: 304591
value: -1000.0

307968
type: SpeciesReference
stoichiometry: 1.0
species: 377895

307956
type: SpeciesReference
stoichiometry: 1.0
species: 377898

379722
type: Reaction
kinetic law: 325395
reactant: 325383
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
name: 13-cis-oxo-retinoicaciddemand

383062
type: LocalParameter
units: 304591
value: 0.0

383061
type: LocalParameter
units: 304591
value: 0.0

383060
type: LocalParameter
units: 304591
value: 13.5135135135135

383059
type: LocalParameter
units: 304591
value: 0.0

325383
type: SpeciesReference
stoichiometry: 1.0
species: 377571

379386
type: Reaction
reactant: 320510
product: 320534
reversible: false
reactant: 320522
notes: GENE_ASSOCIATION: SUBSYSTEM: R Group Synthesis
kinetic law: 320559
name: Rgroupartificialflux
product: 320546
fast: false

320510
type: SpeciesReference
stoichiometry: 1.0
species: 377911

320534
type: SpeciesReference
stoichiometry: 1.0
species: 377643

320522
type: SpeciesReference
stoichiometry: 1.0
species: 378098

382370
type: LocalParameter
units: 304591
value: 0.0

382368
type: LocalParameter
units: 304591
value: 0.0

382366
type: LocalParameter
units: 304591
value: 1000.0

382364
type: LocalParameter
units: 304591
value: 0.0

320546
type: SpeciesReference
stoichiometry: 1.0
species: 377908

377908
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Flavin adenine dinucleotide oxidized

378948
type: Reaction
kinetic law: 312146
product: 312134
reactant: 312122
notes: GENE_ASSOCIATION: (5730.1) SUBSYSTEM: Eicosanoid Metabolism
fast: false
reversible: true
name: Prostaglandin-H2D-isomerase[Precursor]

381244
type: LocalParameter
units: 304591
value: 0.0

381241
type: LocalParameter
units: 304591
value: 0.0

381238
type: LocalParameter
units: 304591
value: 1000.0

381235
type: LocalParameter
units: 304591
value: -1000.0

312134
type: SpeciesReference
stoichiometry: 1.0
species: 378386

378386
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Prostaglandin D2

312122
type: SpeciesReference
stoichiometry: 1.0
species: 378389

378660
type: Reaction
kinetic law: 306324
fast: false
reactant: 306276
reactant: 306288
product: 306312
product: 306300
notes: GENE_ASSOCIATION: (4860.1) SUBSYSTEM: Purine Catabolism
reversible: true
name: purine-nucleosidephosphorylase(Deoxyadenosine)

380190
type: LocalParameter
units: 304591
value: 0.0

380187
type: LocalParameter
units: 304591
value: 0.0

380184
type: LocalParameter
units: 304591
value: 1000.0

380181
type: LocalParameter
units: 304591
value: -1000.0

306276
type: SpeciesReference
stoichiometry: 1.0
species: 377856

306288
type: SpeciesReference
stoichiometry: 1.0
species: 378338

306312
type: SpeciesReference
stoichiometry: 1.0
species: 377688

306300
type: SpeciesReference
stoichiometry: 1.0
species: 377604

378981
type: Reaction
reactant: 312752
fast: false
product: 312776
kinetic law: 312801
reversible: true
product: 312788
notes: GENE_ASSOCIATION: SUBSYSTEM: Ascorbate and Aldarate Metabolism
reactant: 312764
name: gluconolactonase,endoplasmicreticulum

312752
type: SpeciesReference
stoichiometry: 1.0
species: 378041

312776
type: SpeciesReference
stoichiometry: 1.0
species: 378035

381354
type: LocalParameter
units: 304591
value: 0.0

381351
type: LocalParameter
units: 304591
value: 0.0

381348
type: LocalParameter
units: 304591
value: 1000.0

381345
type: LocalParameter
units: 304591
value: -1000.0

312788
type: SpeciesReference
stoichiometry: 1.0
species: 378071

312764
type: SpeciesReference
stoichiometry: 1.0
species: 378086

377790
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Carnosine

379092
type: Reaction
reactant: 315002
product: 315038
kinetic law: 315086
fast: false
product: 315062
reversible: false
reactant: 315014
product: 315050
product: 315074
notes: GENE_ASSOCIATION: (10840.1) SUBSYSTEM: Folate Metabolism
name: formyltetrahydrofolatedehydrogenase
reactant: 315026

315002
type: SpeciesReference
stoichiometry: 1.0
species: 377559

315038
type: SpeciesReference
stoichiometry: 1.0
species: 377817

381685
type: LocalParameter
units: 304591
value: 0.0

381683
type: LocalParameter
units: 304591
value: 0.0

381681
type: LocalParameter
units: 304591
value: 1000.0

381679
type: LocalParameter
units: 304591
value: 0.0

315062
type: SpeciesReference
stoichiometry: 1.0
species: 378236

315014
type: SpeciesReference
stoichiometry: 1.0
species: 378059

315050
type: SpeciesReference
stoichiometry: 1.0
species: 378077

315074
type: SpeciesReference
stoichiometry: 1.0
species: 378497

315026
type: SpeciesReference
stoichiometry: 1.0
species: 378227

378996
type: Reaction
reactant: 313102
fast: false
name: glucuronolactonereductase
product: 313138
notes: GENE_ASSOCIATION: SUBSYSTEM: Ascorbate and Aldarate Metabolism
reactant: 313114
reversible: true
kinetic law: 313162
product: 313150
product: 313126

313102
type: SpeciesReference
stoichiometry: 1.0
species: 378032

313138
type: SpeciesReference
stoichiometry: 1.0
species: 378077

313114
type: SpeciesReference
stoichiometry: 1.0
species: 378227

381404
type: LocalParameter
units: 304591
value: 0.0

381401
type: LocalParameter
units: 304591
value: 0.0

381398
type: LocalParameter
units: 304591
value: 1000.0

381395
type: LocalParameter
units: 304591
value: -1000.0

313150
type: SpeciesReference
stoichiometry: 1.0
species: 378236

313126
type: SpeciesReference
stoichiometry: 1.0
species: 377945

379281
type: Reaction
product: 318578
kinetic law: 318603
notes: GENE_ASSOCIATION: (6546.1) SUBSYSTEM: Transport, Extracellular
reversible: true
name: calcium/sodiumantiporter(1:3),reversible
product: 318591
fast: false
reactant: 318566
reactant: 318554

318578
type: SpeciesReference
stoichiometry: 1.0
species: 377784

382125
type: LocalParameter
units: 304591
value: 0.0

382123
type: LocalParameter
units: 304591
value: 0.0

382121
type: LocalParameter
units: 304591
value: 0.0

382119
type: LocalParameter
units: 304591
value: -1000.0

318591
type: SpeciesReference
stoichiometry: 3.0
species: 378206

318566
type: SpeciesReference
stoichiometry: 3.0
species: 378209

318554
type: SpeciesReference
stoichiometry: 1.0
species: 377781

377781
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Calcium

379849
type: Reaction
kinetic law: 326431
reactant: 326419
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Ethanolexchange

383234
type: LocalParameter
units: 304591
value: 0.0

383233
type: LocalParameter
units: 304591
value: 0.0

383232
type: LocalParameter
units: 304591
value: 13.5135135135135

383231
type: LocalParameter
units: 304591
value: -1000.0

326419
type: SpeciesReference
stoichiometry: 1.0
species: 377898

379200
type: Reaction
reversible: true
notes: GENE_ASSOCIATION: (8671.1) SUBSYSTEM: Transport, Extracellular
fast: false
name: bicarbonatetransport(Na/HCO31:3cotransport)
product: 317153
reactant: 317129
product: 317165
kinetic law: 317177
reactant: 317141

317153
type: SpeciesReference
stoichiometry: 3.0
species: 378092

317129
type: SpeciesReference
stoichiometry: 3.0
species: 378095

317165
type: SpeciesReference
stoichiometry: 1.0
species: 378206

381936
type: LocalParameter
units: 304591
value: 0.0

381934
type: LocalParameter
units: 304591
value: 0.0

381932
type: LocalParameter
units: 304591
value: 1000.0

381930
type: LocalParameter
units: 304591
value: -1000.0

317141
type: SpeciesReference
stoichiometry: 1.0
species: 378209

379791
type: Reaction
kinetic law: 325949
reactant: 325937
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Glycineexchange

383154
type: LocalParameter
units: 304591
value: 0.0

383153
type: LocalParameter
units: 304591
value: 0.0

383152
type: LocalParameter
units: 304591
value: 0.0

383151
type: LocalParameter
units: 304591
value: -1000.0

325937
type: SpeciesReference
stoichiometry: 1.0
species: 377996

377917
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Ferricytochrome c

378927
type: Reaction
kinetic law: 311664
product: 311628
reactant: 311616
product: 311640
product: 311652
notes: GENE_ASSOCIATION: (9380.1) SUBSYSTEM: Pyruvate Metabolism
name: D-lactaldehydedehydrogenase
fast: false
reversible: true
reactant: 311604

381174
type: LocalParameter
units: 304591
value: 0.0

381171
type: LocalParameter
units: 304591
value: 0.0

381168
type: LocalParameter
units: 304591
value: 1000.0

381165
type: LocalParameter
units: 304591
value: -1000.0

311628
type: SpeciesReference
stoichiometry: 1.0
species: 378077

311616
type: SpeciesReference
stoichiometry: 1.0
species: 378227

311640
type: SpeciesReference
stoichiometry: 1.0
species: 378200

311652
type: SpeciesReference
stoichiometry: 1.0
species: 378236

311604
type: SpeciesReference
stoichiometry: 1.0
species: 378152

379038
type: Reaction
notes: GENE_ASSOCIATION: (55586.1) SUBSYSTEM: Inositol Phosphate Metabolism
reactant: 313947
product: 313995
name: inositoloxygenase
fast: false
product: 313983
reversible: false
kinetic law: 314007
product: 313971
reactant: 313959

313947
type: SpeciesReference
stoichiometry: 1.0
species: 378128

313995
type: SpeciesReference
stoichiometry: 1.0
species: 378077

313983
type: SpeciesReference
stoichiometry: 1.0
species: 378059

381544
type: LocalParameter
units: 304591
value: 0.0

381541
type: LocalParameter
units: 304591
value: 0.0

381538
type: LocalParameter
units: 304591
value: 1000.0

381535
type: LocalParameter
units: 304591
value: 0.0

313971
type: SpeciesReference
stoichiometry: 1.0
species: 377960

377960
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Glucuronate

313959
type: SpeciesReference
stoichiometry: 1.0
species: 378266

378600
type: Reaction
reactant: 305097
name: phosphoglyceratekinase
notes: GENE_ASSOCIATION: (5230.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
product: 305122
fast: false
reactant: 305109
kinetic law: 305146
product: 305134
reversible: true

305097
type: SpeciesReference
stoichiometry: 1.0
species: 377616

305122
type: SpeciesReference
stoichiometry: 1.0
species: 377580

305109
type: SpeciesReference
stoichiometry: 1.0
species: 377769

379990
type: LocalParameter
units: 304591
value: 0.0

379987
type: LocalParameter
units: 304591
value: 0.0

379984
type: LocalParameter
units: 304591
value: 1000.0

379981
type: LocalParameter
units: 304591
value: -1000.0

305134
type: SpeciesReference
stoichiometry: 1.0
species: 377700

379599
type: Reaction
kinetic law: 324406
reactant: 324394
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382882
type: LocalParameter
units: 304591
value: 0.0

382880
type: LocalParameter
units: 304591
value: 0.0

382878
type: LocalParameter
units: 304591
value: 13.5135135135135

382876
type: LocalParameter
units: 304591
value: 0.0

324394
type: SpeciesReference
stoichiometry: 1.0
species: 378563

378759
type: Reaction
fast: false
reversible: true
kinetic law: 308125
notes: GENE_ASSOCIATION: (50808.1) SUBSYSTEM: Nucleotides
product: 308101
reactant: 308089
name: adentylatekinase(GTP)
reactant: 308077
product: 308113

380614
type: LocalParameter
units: 304591
value: 0.0

380611
type: LocalParameter
units: 304591
value: 0.0

380608
type: LocalParameter
units: 304591
value: 1000.0

380605
type: LocalParameter
units: 304591
value: -1000.0

308101
type: SpeciesReference
stoichiometry: 1.0
species: 377703

377703
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: ADP

308089
type: SpeciesReference
stoichiometry: 1.0
species: 378026

308077
type: SpeciesReference
stoichiometry: 1.0
species: 377736

377736
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: AMP

308113
type: SpeciesReference
stoichiometry: 1.0
species: 377942

379131
type: Reaction
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
reactant: 315825
reversible: true
product: 315850
product: 315862
name: L-cysteine/glycinereversibleexchanger
reactant: 315837
fast: false
kinetic law: 315874

315825
type: SpeciesReference
stoichiometry: 1.0
species: 377850

315850
type: SpeciesReference
stoichiometry: 1.0
species: 377853

315862
type: SpeciesReference
stoichiometry: 1.0
species: 377993

315837
type: SpeciesReference
stoichiometry: 1.0
species: 377996

381776
type: LocalParameter
units: 304591
value: 0.0

381774
type: LocalParameter
units: 304591
value: 0.0

381772
type: LocalParameter
units: 304591
value: 1000.0

381770
type: LocalParameter
units: 304591
value: -1000.0

304579
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 2.77777777777778E-4
kind: SECOND

304566
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: GRAM

304554
type: SBMLUnit
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE

379737
type: Reaction
kinetic law: 325516
reactant: 325503
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Bicarbonateexchange

383082
type: LocalParameter
units: 304591
value: 0.0

383081
type: LocalParameter
units: 304591
value: 0.0

383080
type: LocalParameter
units: 304591
value: 0.0

383079
type: LocalParameter
units: 304591
value: -1000.0

325503
type: SpeciesReference
stoichiometry: 1.0
species: 378095

379515
type: Reaction
kinetic law: 322745
product: 322733
reactant: 322721
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: sphingosineintracellulartransport

382686
type: LocalParameter
units: 304591
value: 0.0

382684
type: LocalParameter
units: 304591
value: 0.0

382682
type: LocalParameter
units: 304591
value: 1000.0

382680
type: LocalParameter
units: 304591
value: -1000.0

322733
type: SpeciesReference
stoichiometry: 1.0
species: 378476

322721
type: SpeciesReference
stoichiometry: 1.0
species: 378473

379770
type: Reaction
kinetic law: 325780
reactant: 325768
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Deoxyinosineexchange

383126
type: LocalParameter
units: 304591
value: 0.0

383125
type: LocalParameter
units: 304591
value: 0.0

383124
type: LocalParameter
units: 304591
value: 13.5135135135135

383123
type: LocalParameter
units: 304591
value: 0.0

325768
type: SpeciesReference
stoichiometry: 1.0
species: 377880

379410
type: Reaction
kinetic law: 321051
reversible: true
reactant: 321003
reactant: 320979
product: 321039
fast: false
reactant: 320991
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
product: 321015
product: 321027
name: retinaldehydrogenase

382426
type: LocalParameter
units: 304591
value: 0.0

382424
type: LocalParameter
units: 304591
value: 0.0

382422
type: LocalParameter
units: 304591
value: 1000.0

382420
type: LocalParameter
units: 304591
value: -1000.0

321003
type: SpeciesReference
stoichiometry: 1.0
species: 378425

320979
type: SpeciesReference
stoichiometry: 1.0
species: 378059

321039
type: SpeciesReference
stoichiometry: 1.0
species: 378428

320991
type: SpeciesReference
stoichiometry: 1.0
species: 378212

321015
type: SpeciesReference
stoichiometry: 2.0
species: 378077

321027
type: SpeciesReference
stoichiometry: 1.0
species: 378218

379425
type: Reaction
kinetic law: 321354
product: 321341
reactant: 321329
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: 4-oxo-retinoicacidtransport,Nuclear

382461
type: LocalParameter
units: 304591
value: 0.0

382459
type: LocalParameter
units: 304591
value: 0.0

382457
type: LocalParameter
units: 304591
value: 1000.0

382455
type: LocalParameter
units: 304591
value: -1000.0

321341
type: SpeciesReference
stoichiometry: 1.0
species: 378296

321329
type: SpeciesReference
stoichiometry: 1.0
species: 378293

378810
type: Reaction
kinetic law: 309090
product: 309078
reactant: 309066
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: H2Otransport,peroxisomal

380784
type: LocalParameter
units: 304591
value: 0.0

380781
type: LocalParameter
units: 304591
value: 0.0

380778
type: LocalParameter
units: 304591
value: 1000.0

380775
type: LocalParameter
units: 304591
value: -1000.0

309078
type: SpeciesReference
stoichiometry: 1.0
species: 378074

309066
type: SpeciesReference
stoichiometry: 1.0
species: 378059

379110
type: Reaction
name: L-alanine/glycinereversibleexchange
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
product: 315427
reversible: true
fast: false
product: 315439
reactant: 315402
reactant: 315415
kinetic law: 315451

315427
type: SpeciesReference
stoichiometry: 1.0
species: 377724

315439
type: SpeciesReference
stoichiometry: 1.0
species: 377996

315402
type: SpeciesReference
stoichiometry: 1.0
species: 377727

315415
type: SpeciesReference
stoichiometry: 1.0
species: 377993

381727
type: LocalParameter
units: 304591
value: 0.0

381725
type: LocalParameter
units: 304591
value: 0.0

381723
type: LocalParameter
units: 304591
value: 1000.0

381721
type: LocalParameter
units: 304591
value: -1000.0

379125
type: Reaction
reactant: 315704
name: L-threonine/glycinereversibleexchange
product: 315728
reversible: true
kinetic law: 315752
fast: false
reactant: 315716
product: 315740
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular

315704
type: SpeciesReference
stoichiometry: 1.0
species: 377966

315728
type: SpeciesReference
stoichiometry: 1.0
species: 377969

381762
type: LocalParameter
units: 304591
value: 0.0

381760
type: LocalParameter
units: 304591
value: 0.0

381758
type: LocalParameter
units: 304591
value: 1000.0

381756
type: LocalParameter
units: 304591
value: -1000.0

315716
type: SpeciesReference
stoichiometry: 1.0
species: 378503

378503
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Threonine

315740
type: SpeciesReference
stoichiometry: 1.0
species: 378500

379716
type: Reaction
kinetic law: 325347
reactant: 325335
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
name: 4hydroxyretinoicaciddemand

383054
type: LocalParameter
units: 304591
value: 0.0

383053
type: LocalParameter
units: 304591
value: 0.0

383052
type: LocalParameter
units: 304591
value: 13.5135135135135

383051
type: LocalParameter
units: 304591
value: 0.0

325335
type: SpeciesReference
stoichiometry: 1.0
species: 378113

379209
type: Reaction
reactant: 317333
reactant: 317321
product: 317357
product: 317345
kinetic law: 317369
notes: GENE_ASSOCIATION: (64078.1) SUBSYSTEM: Transport, Extracellular
fast: false
name: inosinetransportinviasodium(1:2)symport
reversible: false

317333
type: SpeciesReference
stoichiometry: 2.0
species: 378209

317321
type: SpeciesReference
stoichiometry: 1.0
species: 378137

378137
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Inosine

317357
type: SpeciesReference
stoichiometry: 2.0
species: 378206

317345
type: SpeciesReference
stoichiometry: 1.0
species: 378134

378134
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Inosine

381957
type: LocalParameter
units: 304591
value: 0.0

381955
type: LocalParameter
units: 304591
value: 0.0

381953
type: LocalParameter
units: 304591
value: 1000.0

381951
type: LocalParameter
units: 304591
value: 0.0

379194
type: Reaction
reactant: 317008
fast: false
name: bicarbonatetransport(Cl-/HCO3-exchange)
notes: GENE_ASSOCIATION: (6521.1) SUBSYSTEM: Transport, Extracellular
reactant: 317020
product: 317044
reversible: true
product: 317032
kinetic law: 317056

317008
type: SpeciesReference
stoichiometry: 1.0
species: 377811

317020
type: SpeciesReference
stoichiometry: 1.0
species: 378095

317044
type: SpeciesReference
stoichiometry: 1.0
species: 378092

317032
type: SpeciesReference
stoichiometry: 1.0
species: 377814

381922
type: LocalParameter
units: 304591
value: 0.0

381920
type: LocalParameter
units: 304591
value: 0.0

381918
type: LocalParameter
units: 304591
value: 1000.0

381916
type: LocalParameter
units: 304591
value: -1000.0

379656
type: Reaction
kinetic law: 324863
reactant: 324851
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382974
type: LocalParameter
units: 304591
value: 0.0

382973
type: LocalParameter
units: 304591
value: 0.0

382972
type: LocalParameter
units: 304591
value: 13.5135135135135

382971
type: LocalParameter
units: 304591
value: 0.0

324851
type: SpeciesReference
stoichiometry: 1.0
species: 377763

378609
type: Reaction
kinetic law: 305255
product: 305243
reactant: 305231
notes: GENE_ASSOCIATION: (6120.1) or (6120.2) SUBSYSTEM: Pentose Phosphate Pathway
fast: false
reversible: true
name: ribulose5-phosphate3-epimerase

380020
type: LocalParameter
units: 304591
value: 0.0

380017
type: LocalParameter
units: 304591
value: 0.0

380014
type: LocalParameter
units: 304591
value: 1000.0

380011
type: LocalParameter
units: 304591
value: 0.0

305243
type: SpeciesReference
stoichiometry: 1.0
species: 378551

305231
type: SpeciesReference
stoichiometry: 1.0
species: 378440

378440
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Ribulose 5-phosphate

379873
type: Reaction
kinetic law: 326623
reactant: 326611
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: CO2exchange

383266
type: LocalParameter
units: 304591
value: 0.0

383265
type: LocalParameter
units: 304591
value: 0.0

383264
type: LocalParameter
units: 304591
value: 13.5135135135135

383263
type: LocalParameter
units: 304591
value: -1000.0

326611
type: SpeciesReference
stoichiometry: 1.0
species: 377820

377820
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: CO2

378720
type: Reaction
reactant: 307450
name: alcoholdehydrogenase,forwardrxn(ethanol->acetaldehyde)
reactant: 307438
kinetic law: 307498
product: 307486
notes: GENE_ASSOCIATION: (128.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
product: 307462
fast: false
product: 307474
reversible: false

307450
type: SpeciesReference
stoichiometry: 1.0
species: 378212

307438
type: SpeciesReference
stoichiometry: 1.0
species: 377895

380484
type: LocalParameter
units: 304591
value: 0.0

380481
type: LocalParameter
units: 304591
value: 0.0

380478
type: LocalParameter
units: 304591
value: 1000.0

380475
type: LocalParameter
units: 304591
value: 0.0

307486
type: SpeciesReference
stoichiometry: 1.0
species: 378218

307462
type: SpeciesReference
stoichiometry: 1.0
species: 377661

307474
type: SpeciesReference
stoichiometry: 1.0
species: 378077

378591
type: Reaction
reactant: 304951
notes: GENE_ASSOCIATION: (5211.2) or (5213.1) or (5211.1) or (5211.1 and 5213.1) or (5213.1 and 5211.2) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
product: 304976
product: 304963
kinetic law: 305000
reversible: false
name: phosphofructokinase
reactant: 304939
product: 304988

304951
type: SpeciesReference
stoichiometry: 1.0
species: 377905

304976
type: SpeciesReference
stoichiometry: 1.0
species: 377914

304963
type: SpeciesReference
stoichiometry: 1.0
species: 377700

379960
type: LocalParameter
units: 304591
value: 0.0

379957
type: LocalParameter
units: 304591
value: 0.0

379954
type: LocalParameter
units: 304591
value: 1000.0

379951
type: LocalParameter
units: 304591
value: 0.0

304939
type: SpeciesReference
stoichiometry: 1.0
species: 377769

304988
type: SpeciesReference
stoichiometry: 1.0
species: 378077

379356
type: Reaction
kinetic law: 319917
product: 319905
reactant: 319893
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: false
name: xanthinediffusioninperoxisome

382300
type: LocalParameter
units: 304591
value: 0.0

382298
type: LocalParameter
units: 304591
value: 0.0

382296
type: LocalParameter
units: 304591
value: 1000.0

382294
type: LocalParameter
units: 304591
value: 0.0

319905
type: SpeciesReference
stoichiometry: 1.0
species: 378545

319893
type: SpeciesReference
stoichiometry: 1.0
species: 378542

379104
type: Reaction
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
product: 315304
kinetic law: 315328
name: D-Serine/Glycinereversibleexchange
reversible: true
reactant: 315292
fast: false
product: 315316
reactant: 315280

315304
type: SpeciesReference
stoichiometry: 1.0
species: 377996

381713
type: LocalParameter
units: 304591
value: 0.0

381711
type: LocalParameter
units: 304591
value: 0.0

381709
type: LocalParameter
units: 304591
value: 1000.0

381707
type: LocalParameter
units: 304591
value: -1000.0

315292
type: SpeciesReference
stoichiometry: 1.0
species: 378452

315316
type: SpeciesReference
stoichiometry: 1.0
species: 378449

315280
type: SpeciesReference
stoichiometry: 1.0
species: 377993

379020
type: Reaction
reversible: true
reactant: 313561
notes: GENE_ASSOCIATION: (285216.1) or (80068.1) SUBSYSTEM: Folate Metabolism
reactant: 313549
product: 313573
kinetic law: 313598
product: 313585
fast: false

313561
type: SpeciesReference
stoichiometry: 1.0
species: 378212

313549
type: SpeciesReference
stoichiometry: 1.0
species: 378197

313573
type: SpeciesReference
stoichiometry: 1.0
species: 378194

378194
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 5,10-Methenyltetrahydrofolate

381484
type: LocalParameter
units: 304591
value: 0.0

381481
type: LocalParameter
units: 304591
value: 0.0

381478
type: LocalParameter
units: 304591
value: 1000.0

381475
type: LocalParameter
units: 304591
value: -1000.0

313585
type: SpeciesReference
stoichiometry: 1.0
species: 378218

379404
type: Reaction
notes: GENE_ASSOCIATION: (11001.1) SUBSYSTEM: Fatty acid activation
name: fatty-acid--CoAligase
product: 320895
product: 320907
reactant: 320859
product: 320919
fast: false
reactant: 320871
reversible: false
kinetic law: 320931
reactant: 320883

320895
type: SpeciesReference
stoichiometry: 1.0
species: 377730

320907
type: SpeciesReference
stoichiometry: 1.0
species: 378359

320859
type: SpeciesReference
stoichiometry: 1.0
species: 377769

320919
type: SpeciesReference
stoichiometry: 1.0
species: 378371

320871
type: SpeciesReference
stoichiometry: 1.0
species: 377826

382412
type: LocalParameter
units: 304591
value: 0.0

382410
type: LocalParameter
units: 304591
value: 0.0

382408
type: LocalParameter
units: 304591
value: 1000.0

382406
type: LocalParameter
units: 304591
value: 0.0

320883
type: SpeciesReference
stoichiometry: 1.0
species: 378365

378365
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: pristanic acid

377565
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: (S)-Propane-1,2-diol

378585
type: Reaction
fast: false
product: 304843
reactant: 304795
notes: GENE_ASSOCIATION: (2597.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
product: 304819
reversible: true
kinetic law: 304855
name: glyceraldehyde-3-phosphatedehydrogenase
reactant: 304807
product: 304831
reactant: 304783

304843
type: SpeciesReference
stoichiometry: 1.0
species: 378218

304795
type: SpeciesReference
stoichiometry: 1.0
species: 378212

304819
type: SpeciesReference
stoichiometry: 1.0
species: 377580

379940
type: LocalParameter
units: 304591
value: 0.0

379937
type: LocalParameter
units: 304591
value: 0.0

379934
type: LocalParameter
units: 304591
value: 1000.0

379931
type: LocalParameter
units: 304591
value: -1000.0

304807
type: SpeciesReference
stoichiometry: 1.0
species: 378338

304831
type: SpeciesReference
stoichiometry: 1.0
species: 378077

304783
type: SpeciesReference
stoichiometry: 1.0
species: 377933

378873
type: Reaction
product: 310369
product: 310357
name: formate-tetrahydrofolateligase
fast: false
product: 310381
reactant: 310344
reactant: 310332
reversible: true
notes: GENE_ASSOCIATION: (4522.1) SUBSYSTEM: Folate Metabolism
reactant: 310320
kinetic law: 310393

310369
type: SpeciesReference
stoichiometry: 1.0
species: 377700

310357
type: SpeciesReference
stoichiometry: 1.0
species: 377559

310381
type: SpeciesReference
stoichiometry: 1.0
species: 378338

310344
type: SpeciesReference
stoichiometry: 1.0
species: 378497

310332
type: SpeciesReference
stoichiometry: 1.0
species: 377923

310320
type: SpeciesReference
stoichiometry: 1.0
species: 377769

380994
type: LocalParameter
units: 304591
value: 0.0

380991
type: LocalParameter
units: 304591
value: 0.0

380988
type: LocalParameter
units: 304591
value: 0.0

380985
type: LocalParameter
units: 304591
value: -1000.0

378888
type: Reaction
reactant: 310695
notes: GENE_ASSOCIATION: (7384.1) and (7388.1) and (4519.1) and (29796.2) and (10975.1) and (7385.1) and (7386.1) and (1537.1) and (27089.1) and (7381.1) or (7384.1) and (7388.1) and (4519.1) and (29796.1) and (10975.1) and (7385.1) and (1537.1) and (7386.1) and (27089.1) and (7381.1) SUBSYSTEM: Oxidative Phosphorylation
fast: false
product: 310743
product: 310719
reversible: false
kinetic law: 310755
product: 310731
reactant: 310707
reactant: 310683
name: ubiquinol-6cytochromecreductase,ComplexIII

310695
type: SpeciesReference
stoichiometry: 2.0
species: 378083

310743
type: SpeciesReference
stoichiometry: 1.0
species: 378410

310719
type: SpeciesReference
stoichiometry: 2.0
species: 377920

377920
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Ferrocytochrome C

381044
type: LocalParameter
units: 304591
value: 0.0

381041
type: LocalParameter
units: 304591
value: 0.0

381038
type: LocalParameter
units: 304591
value: 1000.0

381035
type: LocalParameter
units: 304591
value: 0.0

310731
type: SpeciesReference
stoichiometry: 4.0
species: 378077

310707
type: SpeciesReference
stoichiometry: 1.0
species: 378413

310683
type: SpeciesReference
stoichiometry: 2.0
species: 377917

379173
type: Reaction
kinetic law: 316683
product: 316670
reactant: 316658
notes: GENE_ASSOCIATION: (124935.1) or (117247.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true

381873
type: LocalParameter
units: 304591
value: 0.0

381871
type: LocalParameter
units: 304591
value: 0.0

381869
type: LocalParameter
units: 304591
value: 1000.0

381867
type: LocalParameter
units: 304591
value: -1000.0

316670
type: SpeciesReference
stoichiometry: 1.0
species: 378332

316658
type: SpeciesReference
stoichiometry: 1.0
species: 378335

379635
type: Reaction
kinetic law: 324695
reactant: 324683
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382946
type: LocalParameter
units: 304591
value: 0.0

382945
type: LocalParameter
units: 304591
value: 0.0

382944
type: LocalParameter
units: 304591
value: 13.5135135135135

382943
type: LocalParameter
units: 304591
value: 0.0

324683
type: SpeciesReference
stoichiometry: 1.0
species: 378158

379188
type: Reaction
kinetic law: 316936
product: 316924
product: 316911
reactant: 316899
reactant: 316887
fast: false
reversible: true
name: urea,watercotransport

381908
type: LocalParameter
units: 304591
value: 0.0

381906
type: LocalParameter
units: 304591
value: 0.0

381904
type: LocalParameter
units: 304591
value: 1000.0

381902
type: LocalParameter
units: 304591
value: 0.0

316924
type: SpeciesReference
stoichiometry: 1.0
species: 378530

316911
type: SpeciesReference
stoichiometry: 1.0
species: 378059

316899
type: SpeciesReference
stoichiometry: 1.0
species: 378533

316887
type: SpeciesReference
stoichiometry: 1.0
species: 378062

379852
type: Reaction
kinetic law: 326455
reactant: 326443
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Aspartateexchange

383238
type: LocalParameter
units: 304591
value: 0.0

383237
type: LocalParameter
units: 304591
value: 0.0

383236
type: LocalParameter
units: 304591
value: 0.0

383235
type: LocalParameter
units: 304591
value: -1000.0

326443
type: SpeciesReference
stoichiometry: 1.0
species: 377766

377766
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Aspartate

379867
type: Reaction
kinetic law: 326575
reactant: 326563
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: 4-Aminobutanoateexchange

383258
type: LocalParameter
units: 304591
value: 0.0

383257
type: LocalParameter
units: 304591
value: 0.0

383256
type: LocalParameter
units: 304591
value: 13.5135135135135

383255
type: LocalParameter
units: 304591
value: -1000.0

326563
type: SpeciesReference
stoichiometry: 1.0
species: 377622

379473
type: Reaction
kinetic law: 322092
product: 322079
reactant: 322067
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: acetaldehydeperoxisomaldiffusion

382588
type: LocalParameter
units: 304591
value: 0.0

382586
type: LocalParameter
units: 304591
value: 0.0

382584
type: LocalParameter
units: 304591
value: 1000.0

382582
type: LocalParameter
units: 304591
value: -1000.0

322079
type: SpeciesReference
stoichiometry: 1.0
species: 377661

322067
type: SpeciesReference
stoichiometry: 1.0
species: 377670

379419
type: Reaction
kinetic law: 321269
product: 321257
reactant: 321245
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: 4-hydroxyretinoicacidtransport,Nuclear

382447
type: LocalParameter
units: 304591
value: 0.0

382445
type: LocalParameter
units: 304591
value: 0.0

382443
type: LocalParameter
units: 304591
value: 1000.0

382441
type: LocalParameter
units: 304591
value: -1000.0

321257
type: SpeciesReference
stoichiometry: 1.0
species: 378113

321245
type: SpeciesReference
stoichiometry: 1.0
species: 378110

378110
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 4 hydroxy retinoic acid

379083
type: Reaction
kinetic law: 314870
product: 314858
reactant: 314846
notes: GENE_ASSOCIATION: (84889.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: false

381664
type: LocalParameter
units: 304591
value: 0.0

381662
type: LocalParameter
units: 304591
value: 0.0

381660
type: LocalParameter
units: 304591
value: 1000.0

381658
type: LocalParameter
units: 304591
value: 0.0

314858
type: SpeciesReference
stoichiometry: 1.0
species: 377748

314846
type: SpeciesReference
stoichiometry: 1.0
species: 377751

378819
type: Reaction
kinetic law: 309198
product: 309186
reactant: 309174
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: ammoniaperoxisomaltransport

380814
type: LocalParameter
units: 304591
value: 0.0

380811
type: LocalParameter
units: 304591
value: 0.0

380808
type: LocalParameter
units: 304591
value: 1000.0

380805
type: LocalParameter
units: 304591
value: -1000.0

309186
type: SpeciesReference
stoichiometry: 1.0
species: 378254

309174
type: SpeciesReference
stoichiometry: 1.0
species: 378245

378951
type: Reaction
kinetic law: 312182
product: 312170
reactant: 312158
notes: GENE_ASSOCIATION: (5740.1) SUBSYSTEM: Eicosanoid Metabolism
fast: false
reversible: true
name: ProstaglandinI2synthase

381254
type: LocalParameter
units: 304591
value: 0.0

381251
type: LocalParameter
units: 304591
value: 0.0

381248
type: LocalParameter
units: 304591
value: 1000.0

381245
type: LocalParameter
units: 304591
value: 0.0

312170
type: SpeciesReference
stoichiometry: 1.0
species: 378395

378395
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Prostaglandin I2

312158
type: SpeciesReference
stoichiometry: 1.0
species: 378392

379467
type: Reaction
kinetic law: 321994
product: 321982
reactant: 321969
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: false
name: urateexportfromcytosol

382574
type: LocalParameter
units: 304591
value: 0.0

382572
type: LocalParameter
units: 304591
value: 0.0

382570
type: LocalParameter
units: 304591
value: 1000.0

382568
type: LocalParameter
units: 304591
value: 0.0

321982
type: SpeciesReference
stoichiometry: 1.0
species: 378524

321969
type: SpeciesReference
stoichiometry: 1.0
species: 378521

379245
type: Reaction
kinetic law: 318024
product: 318012
reactant: 317999
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: fattyacidtransportviadiffusion

382041
type: LocalParameter
units: 304591
value: 0.0

382039
type: LocalParameter
units: 304591
value: 0.0

382037
type: LocalParameter
units: 304591
value: 1000.0

382035
type: LocalParameter
units: 304591
value: -1000.0

318012
type: SpeciesReference
stoichiometry: 1.0
species: 377706

317999
type: SpeciesReference
stoichiometry: 1.0
species: 377709

377709
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: adrenic acid

379251
type: Reaction
kinetic law: 318096
product: 318084
reactant: 318072
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: fattyacidtransportviadiffusion

382055
type: LocalParameter
units: 304591
value: 0.0

382053
type: LocalParameter
units: 304591
value: 0.0

382051
type: LocalParameter
units: 304591
value: 1000.0

382049
type: LocalParameter
units: 304591
value: -1000.0

318084
type: SpeciesReference
stoichiometry: 1.0
species: 377844

318072
type: SpeciesReference
stoichiometry: 1.0
species: 377847

379836
type: Reaction
kinetic law: 326310
reactant: 326298
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Lactateexchange

383214
type: LocalParameter
units: 304591
value: 0.0

383213
type: LocalParameter
units: 304591
value: 0.0

383212
type: LocalParameter
units: 304591
value: 13.5135135135135

383211
type: LocalParameter
units: 304591
value: -1000.0

326298
type: SpeciesReference
stoichiometry: 1.0
species: 378149

378149
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Lactate

378729
type: Reaction
kinetic law: 307630
product: 307618
reactant: 307606
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: o2transport(diffusion)

380514
type: LocalParameter
units: 304591
value: 0.0

380511
type: LocalParameter
units: 304591
value: 0.0

380508
type: LocalParameter
units: 304591
value: 1000.0

380505
type: LocalParameter
units: 304591
value: -1000.0

307618
type: SpeciesReference
stoichiometry: 1.0
species: 378266

307606
type: SpeciesReference
stoichiometry: 1.0
species: 378269

378269
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: O2

379698
type: Reaction
kinetic law: 325200
reactant: 325188
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

383030
type: LocalParameter
units: 304591
value: 0.0

383029
type: LocalParameter
units: 304591
value: 0.0

383028
type: LocalParameter
units: 304591
value: 13.5135135135135

383027
type: LocalParameter
units: 304591
value: 0.0

325188
type: SpeciesReference
stoichiometry: 1.0
species: 377781

379482
type: Reaction
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
name: retinaldehydrogenase
product: 322213
product: 322238
product: 322226
reactant: 322200
kinetic law: 322250
reversible: true
reactant: 322176
reactant: 322188

322213
type: SpeciesReference
stoichiometry: 1.0
species: 377574

322238
type: SpeciesReference
stoichiometry: 1.0
species: 378218

322226
type: SpeciesReference
stoichiometry: 2.0
species: 378077

322200
type: SpeciesReference
stoichiometry: 1.0
species: 378422

382609
type: LocalParameter
units: 304591
value: 0.0

382607
type: LocalParameter
units: 304591
value: 0.0

382605
type: LocalParameter
units: 304591
value: 1000.0

382603
type: LocalParameter
units: 304591
value: -1000.0

322176
type: SpeciesReference
stoichiometry: 1.0
species: 378059

322188
type: SpeciesReference
stoichiometry: 1.0
species: 378212

379740
type: Reaction
kinetic law: 325540
reactant: 325528
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Cystineexchange

383086
type: LocalParameter
units: 304591
value: 0.0

383085
type: LocalParameter
units: 304591
value: 0.0

383084
type: LocalParameter
units: 304591
value: 13.5135135135135

383083
type: LocalParameter
units: 304591
value: -1000.0

325528
type: SpeciesReference
stoichiometry: 1.0
species: 377637

378930
type: Reaction
reversible: true
name: D-Lactaldehyde:NAD+oxidoreductase(glutathione-formylating)
reactant: 311676
kinetic law: 311748
reactant: 311700
product: 311712
reactant: 311688
notes: GENE_ASSOCIATION: (128.1) SUBSYSTEM: Pyruvate Metabolism
product: 311724
fast: false
product: 311736

311676
type: SpeciesReference
stoichiometry: 1.0
species: 378017

381184
type: LocalParameter
units: 304591
value: 0.0

381181
type: LocalParameter
units: 304591
value: 0.0

381178
type: LocalParameter
units: 304591
value: 1000.0

381175
type: LocalParameter
units: 304591
value: -1000.0

311700
type: SpeciesReference
stoichiometry: 1.0
species: 378212

311712
type: SpeciesReference
stoichiometry: 1.0
species: 378077

311688
type: SpeciesReference
stoichiometry: 1.0
species: 378152

311724
type: SpeciesReference
stoichiometry: 1.0
species: 378170

311736
type: SpeciesReference
stoichiometry: 1.0
species: 378218

379230
type: Reaction
kinetic law: 317769
product: 317757
reactant: 317745
notes: GENE_ASSOCIATION: (6584.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: Cholineuniport

382006
type: LocalParameter
units: 304591
value: 0.0

382004
type: LocalParameter
units: 304591
value: 0.0

382002
type: LocalParameter
units: 304591
value: 1000.0

382000
type: LocalParameter
units: 304591
value: -1000.0

317757
type: SpeciesReference
stoichiometry: 1.0
species: 377793

317745
type: SpeciesReference
stoichiometry: 1.0
species: 377796

379560
type: Reaction
kinetic law: 323452
product: 323440
reactant: 323428
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true

382791
type: LocalParameter
units: 304591
value: 0.0

382789
type: LocalParameter
units: 304591
value: 0.0

382787
type: LocalParameter
units: 304591
value: 1000.0

382785
type: LocalParameter
units: 304591
value: -1000.0

323440
type: SpeciesReference
stoichiometry: 1.0
species: 378563

323428
type: SpeciesReference
stoichiometry: 1.0
species: 378395

378708
type: Reaction
kinetic law: 307233
product: 307221
reactant: 307208
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: H2Otransport,nuclear

380444
type: LocalParameter
units: 304591
value: 0.0

380441
type: LocalParameter
units: 304591
value: 0.0

380438
type: LocalParameter
units: 304591
value: 1000.0

380435
type: LocalParameter
units: 304591
value: -1000.0

307221
type: SpeciesReference
stoichiometry: 1.0
species: 378059

307208
type: SpeciesReference
stoichiometry: 1.0
species: 378068

377930
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Fumarate

379317
type: Reaction
fast: false
name: superoxidedismutase,peroxisome
reactant: 319206
product: 319230
reversible: false
product: 319242
reactant: 319218
notes: GENE_ASSOCIATION: (6647.1) SUBSYSTEM: ROS Detoxification
kinetic law: 319255

319206
type: SpeciesReference
stoichiometry: 2.0
species: 378089

319230
type: SpeciesReference
stoichiometry: 1.0
species: 378056

319242
type: SpeciesReference
stoichiometry: 1.0
species: 378278

319218
type: SpeciesReference
stoichiometry: 2.0
species: 378287

382209
type: LocalParameter
units: 304591
value: 0.0

382207
type: LocalParameter
units: 304591
value: 0.0

382205
type: LocalParameter
units: 304591
value: 1000.0

382203
type: LocalParameter
units: 304591
value: 0.0

378714
type: Reaction
product: 307329
kinetic law: 307341
product: 307317
notes: GENE_ASSOCIATION: (6389.1 and 6392.1 and 6391.1 and 6390.1) SUBSYSTEM: Citric Acid Cycle
reversible: true
name: succinatedehydrogenase
reactant: 307293
reactant: 307305
fast: false

307329
type: SpeciesReference
stoichiometry: 1.0
species: 377930

380464
type: LocalParameter
units: 304591
value: 0.0

380461
type: LocalParameter
units: 304591
value: 0.0

380458
type: LocalParameter
units: 304591
value: 1000.0

380455
type: LocalParameter
units: 304591
value: -1000.0

307317
type: SpeciesReference
stoichiometry: 1.0
species: 377911

307293
type: SpeciesReference
stoichiometry: 1.0
species: 377908

307305
type: SpeciesReference
stoichiometry: 1.0
species: 378491

379506
type: Reaction
kinetic law: 322588
product: 322576
reactant: 322564
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true

382665
type: LocalParameter
units: 304591
value: 0.0

382663
type: LocalParameter
units: 304591
value: 0.0

382661
type: LocalParameter
units: 304591
value: 1000.0

382659
type: LocalParameter
units: 304591
value: -1000.0

322576
type: SpeciesReference
stoichiometry: 1.0
species: 378326

322564
type: SpeciesReference
stoichiometry: 1.0
species: 378323

379734
type: Reaction
kinetic law: 325491
reactant: 325479
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Oxalateexchange

383078
type: LocalParameter
units: 304591
value: 0.0

383077
type: LocalParameter
units: 304591
value: 0.0

383076
type: LocalParameter
units: 304591
value: 0.0

383075
type: LocalParameter
units: 304591
value: -1000.0

325479
type: SpeciesReference
stoichiometry: 1.0
species: 378302

378612
type: Reaction
reactant: 305280
kinetic law: 305317
name: transaldolase
notes: GENE_ASSOCIATION: (6888.1) SUBSYSTEM: Pentose Phosphate Pathway
reversible: true
product: 305305
fast: false
product: 305292
reactant: 305268

305280
type: SpeciesReference
stoichiometry: 1.0
species: 378443

380030
type: LocalParameter
units: 304591
value: 0.0

380027
type: LocalParameter
units: 304591
value: 0.0

380024
type: LocalParameter
units: 304591
value: 1000.0

380021
type: LocalParameter
units: 304591
value: -1000.0

305305
type: SpeciesReference
stoichiometry: 1.0
species: 377905

305292
type: SpeciesReference
stoichiometry: 1.0
species: 377892

305268
type: SpeciesReference
stoichiometry: 1.0
species: 377933

378993
type: Reaction
product: 313054
reversible: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
product: 313066
reactant: 313029
kinetic law: 313090
fast: false
reactant: 313017
reactant: 313041
name: glycineoxidase,perixosomal
product: 313078

313054
type: SpeciesReference
stoichiometry: 1.0
species: 377990

313066
type: SpeciesReference
stoichiometry: 1.0
species: 378056

313029
type: SpeciesReference
stoichiometry: 1.0
species: 378074

381394
type: LocalParameter
units: 304591
value: 0.0

381391
type: LocalParameter
units: 304591
value: 0.0

381388
type: LocalParameter
units: 304591
value: 1000.0

381385
type: LocalParameter
units: 304591
value: 0.0

313017
type: SpeciesReference
stoichiometry: 1.0
species: 377999

313041
type: SpeciesReference
stoichiometry: 1.0
species: 378278

313078
type: SpeciesReference
stoichiometry: 1.0
species: 378254

379293
type: Reaction
product: 318853
kinetic law: 318879
reactant: 318827
name: K+-Cl-cotransporter(NH4+)
reactant: 318840
notes: GENE_ASSOCIATION: (10723.1) SUBSYSTEM: Transport, Extracellular
reversible: true
fast: false
product: 318866

318853
type: SpeciesReference
stoichiometry: 1.0
species: 377811

382153
type: LocalParameter
units: 304591
value: 0.0

382151
type: LocalParameter
units: 304591
value: 0.0

382149
type: LocalParameter
units: 304591
value: 1000.0

382147
type: LocalParameter
units: 304591
value: -1000.0

318827
type: SpeciesReference
stoichiometry: 1.0
species: 377814

318840
type: SpeciesReference
stoichiometry: 1.0
species: 378248

318866
type: SpeciesReference
stoichiometry: 1.0
species: 378245

379212
type: Reaction
notes: GENE_ASSOCIATION: (6526.1) or (159963.1) or (6524.1) SUBSYSTEM: Transport, Extracellular
reactant: 317393
name: glucosetransportviasodiumsymport
fast: false
reactant: 317381
product: 317417
kinetic law: 317429
product: 317405
reversible: true

317393
type: SpeciesReference
stoichiometry: 1.0
species: 378209

317381
type: SpeciesReference
stoichiometry: 1.0
species: 377954

317417
type: SpeciesReference
stoichiometry: 1.0
species: 378206

381964
type: LocalParameter
units: 304591
value: 0.0

381962
type: LocalParameter
units: 304591
value: 0.0

381960
type: LocalParameter
units: 304591
value: 1000.0

381958
type: LocalParameter
units: 304591
value: 0.0

317405
type: SpeciesReference
stoichiometry: 1.0
species: 377951

379749
type: Reaction
kinetic law: 325612
reactant: 325600
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: 4-Pyridoxateexchange

383098
type: LocalParameter
units: 304591
value: 0.0

383097
type: LocalParameter
units: 304591
value: 0.0

383096
type: LocalParameter
units: 304591
value: 13.5135135135135

383095
type: LocalParameter
units: 304591
value: -1000.0

325600
type: SpeciesReference
stoichiometry: 1.0
species: 377631

377832
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: Coenzyme A

378939
type: Reaction
product: 311953
notes: GENE_ASSOCIATION: (5832.1) SUBSYSTEM: Urea cycle/amino group metabolism
kinetic law: 311965
reactant: 311929
reversible: false
reactant: 311917
fast: false
product: 311941
name: glutamate5-kinase(m)

311953
type: SpeciesReference
stoichiometry: 1.0
species: 377972

381214
type: LocalParameter
units: 304591
value: 0.0

381211
type: LocalParameter
units: 304591
value: 0.0

381208
type: LocalParameter
units: 304591
value: 1000.0

381205
type: LocalParameter
units: 304591
value: 0.0

311929
type: SpeciesReference
stoichiometry: 1.0
species: 377984

311917
type: SpeciesReference
stoichiometry: 1.0
species: 377772

311941
type: SpeciesReference
stoichiometry: 1.0
species: 377703

379206
type: Reaction
reversible: false
kinetic law: 317309
notes: GENE_ASSOCIATION: (64078.1) SUBSYSTEM: Transport, Extracellular
fast: false
reactant: 317273
product: 317297
name: adenosinetransport(1:2Na/Adncotransport)
product: 317285
reactant: 317261

381950
type: LocalParameter
units: 304591
value: 0.0

381948
type: LocalParameter
units: 304591
value: 0.0

381946
type: LocalParameter
units: 304591
value: 1000.0

381944
type: LocalParameter
units: 304591
value: 0.0

317273
type: SpeciesReference
stoichiometry: 2.0
species: 378209

317297
type: SpeciesReference
stoichiometry: 2.0
species: 378206

317285
type: SpeciesReference
stoichiometry: 1.0
species: 377694

317261
type: SpeciesReference
stoichiometry: 1.0
species: 377697

377697
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Adenosine

379782
type: Reaction
kinetic law: 325876
reactant: 325864
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Tryptophanexchange

383142
type: LocalParameter
units: 304591
value: 0.0

383141
type: LocalParameter
units: 304591
value: 0.0

383140
type: LocalParameter
units: 304591
value: 0.0

383139
type: LocalParameter
units: 304591
value: -1000.0

325864
type: SpeciesReference
stoichiometry: 1.0
species: 378509

378801
type: Reaction
reactant: 308861
kinetic law: 308922
reactant: 308873
product: 308886
reversible: false
notes: GENE_ASSOCIATION: (64080.1) SUBSYSTEM: Pentose Phosphate Pathway
product: 308910
product: 308898
name: Deoxyribokinase
fast: false

308861
type: SpeciesReference
stoichiometry: 1.0
species: 377769

380754
type: LocalParameter
units: 304591
value: 0.0

380751
type: LocalParameter
units: 304591
value: 0.0

380748
type: LocalParameter
units: 304591
value: 1000.0

380745
type: LocalParameter
units: 304591
value: 0.0

308873
type: SpeciesReference
stoichiometry: 1.0
species: 377886

308886
type: SpeciesReference
stoichiometry: 1.0
species: 377607

308910
type: SpeciesReference
stoichiometry: 1.0
species: 378077

308898
type: SpeciesReference
stoichiometry: 1.0
species: 377700

379437
type: Reaction
kinetic law: 321511
product: 321499
reactant: 321487
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
fast: false
reversible: true
name: 13-cis-4-oxo-retinoicacidisomerase

382489
type: LocalParameter
units: 304591
value: 0.0

382487
type: LocalParameter
units: 304591
value: 0.0

382485
type: LocalParameter
units: 304591
value: 1000.0

382483
type: LocalParameter
units: 304591
value: -1000.0

321499
type: SpeciesReference
stoichiometry: 1.0
species: 377568

321487
type: SpeciesReference
stoichiometry: 1.0
species: 378293

379824
type: Reaction
kinetic law: 326214
reactant: 326202
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Prolineexchange

383198
type: LocalParameter
units: 304591
value: 0.0

383197
type: LocalParameter
units: 304591
value: 0.0

383196
type: LocalParameter
units: 304591
value: 0.0

383195
type: LocalParameter
units: 304591
value: -1000.0

326202
type: SpeciesReference
stoichiometry: 1.0
species: 378380

379728
type: Reaction
kinetic law: 325443
reactant: 325431
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Retinoateexchange

383070
type: LocalParameter
units: 304591
value: 0.0

383069
type: LocalParameter
units: 304591
value: 0.0

383068
type: LocalParameter
units: 304591
value: 13.5135135135135

383067
type: LocalParameter
units: 304591
value: -1000.0

325431
type: SpeciesReference
stoichiometry: 1.0
species: 378431

379137
type: Reaction
kinetic law: 315971
product: 315958
reactant: 315946
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: false
name: glucosetransportviamembranevesicle

381789
type: LocalParameter
units: 304591
value: 0.0

381787
type: LocalParameter
units: 304591
value: 0.0

381785
type: LocalParameter
units: 304591
value: 1000.0

381783
type: LocalParameter
units: 304591
value: 0.0

315958
type: SpeciesReference
stoichiometry: 1.0
species: 377954

315946
type: SpeciesReference
stoichiometry: 1.0
species: 377957

379143
type: Reaction
reactant: 316127
name: L-aspartatetransportviaNa,HsymportandKantiport
product: 316175
product: 316163
fast: false
kinetic law: 316187
product: 316139
reactant: 316103
reversible: false
reactant: 316091
reactant: 316115
notes: GENE_ASSOCIATION: (6505.1) SUBSYSTEM: Transport, Extracellular
product: 316151

316127
type: SpeciesReference
stoichiometry: 3.0
species: 378209

316175
type: SpeciesReference
stoichiometry: 3.0
species: 378206

316163
type: SpeciesReference
stoichiometry: 1.0
species: 378143

381803
type: LocalParameter
units: 304591
value: 0.0

381801
type: LocalParameter
units: 304591
value: 0.0

381799
type: LocalParameter
units: 304591
value: 1000.0

381797
type: LocalParameter
units: 304591
value: 0.0

316139
type: SpeciesReference
stoichiometry: 1.0
species: 377763

316103
type: SpeciesReference
stoichiometry: 1.0
species: 378080

316091
type: SpeciesReference
stoichiometry: 1.0
species: 377766

316115
type: SpeciesReference
stoichiometry: 1.0
species: 378140

316151
type: SpeciesReference
stoichiometry: 1.0
species: 378077

379422
type: Reaction
kinetic law: 321317
product: 321305
reactant: 321293
reactant: 321281
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
fast: false
reversible: false
name: 4-oxo-retinoicacidformation(oxidation)

382454
type: LocalParameter
units: 304591
value: 0.0

382452
type: LocalParameter
units: 304591
value: 0.0

382450
type: LocalParameter
units: 304591
value: 1000.0

382448
type: LocalParameter
units: 304591
value: 0.0

321305
type: SpeciesReference
stoichiometry: 2.0
species: 378293

321293
type: SpeciesReference
stoichiometry: 2.0
species: 378428

321281
type: SpeciesReference
stoichiometry: 1.0
species: 378266

379416
type: Reaction
name: retinoicacidhydroxylation(P450)
fast: false
reactant: 321171
product: 321221
reactant: 321183
kinetic law: 321233
product: 321208
product: 321196
reactant: 321147
reversible: false
reactant: 321159
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism

321171
type: SpeciesReference
stoichiometry: 1.0
species: 378266

321221
type: SpeciesReference
stoichiometry: 1.0
species: 378227

321183
type: SpeciesReference
stoichiometry: 1.0
species: 378428

382440
type: LocalParameter
units: 304591
value: 0.0

382438
type: LocalParameter
units: 304591
value: 0.0

382436
type: LocalParameter
units: 304591
value: 1000.0

382434
type: LocalParameter
units: 304591
value: 0.0

321208
type: SpeciesReference
stoichiometry: 1.0
species: 378110

321196
type: SpeciesReference
stoichiometry: 1.0
species: 378059

321147
type: SpeciesReference
stoichiometry: 1.0
species: 378077

321159
type: SpeciesReference
stoichiometry: 1.0
species: 378236

378822
type: Reaction
name: Glycolatedehydrogenase(NADP)
product: 309259
reactant: 309235
fast: false
reversible: false
reactant: 309223
notes: GENE_ASSOCIATION: (9380.1) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
reactant: 309210
product: 309247
kinetic law: 309271

309259
type: SpeciesReference
stoichiometry: 1.0
species: 378227

309235
type: SpeciesReference
stoichiometry: 1.0
species: 378236

309223
type: SpeciesReference
stoichiometry: 1.0
species: 378077

309210
type: SpeciesReference
stoichiometry: 1.0
species: 377987

309247
type: SpeciesReference
stoichiometry: 1.0
species: 378005

380824
type: LocalParameter
units: 304591
value: 0.0

380821
type: LocalParameter
units: 304591
value: 0.0

380818
type: LocalParameter
units: 304591
value: 1000.0

380815
type: LocalParameter
units: 304591
value: 0.0

379626
type: Reaction
kinetic law: 324622
reactant: 324610
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382934
type: LocalParameter
units: 304591
value: 0.0

382933
type: LocalParameter
units: 304591
value: 0.0

382932
type: LocalParameter
units: 304591
value: 13.5135135135135

382930
type: LocalParameter
units: 304591
value: 0.0

324610
type: SpeciesReference
stoichiometry: 1.0
species: 378332

378164
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: lignoceric acid

379122
type: Reaction
reactant: 315644
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
reactant: 315656
product: 315680
product: 315668
reversible: true
fast: false
name: L-threonine/glycinereversibleexchange
kinetic law: 315692

315644
type: SpeciesReference
stoichiometry: 1.0
species: 377993

315656
type: SpeciesReference
stoichiometry: 1.0
species: 378503

315680
type: SpeciesReference
stoichiometry: 1.0
species: 378500

315668
type: SpeciesReference
stoichiometry: 1.0
species: 377996

381755
type: LocalParameter
units: 304591
value: 0.0

381753
type: LocalParameter
units: 304591
value: 0.0

381751
type: LocalParameter
units: 304591
value: 1000.0

381749
type: LocalParameter
units: 304591
value: -1000.0

378765
type: Reaction
product: 308245
notes: GENE_ASSOCIATION: (7001.3) or (5052.3) or (2876.2) or (5052.2) or (2876.1) or (5052.1) or (7001.1) or (2879.1) or (7001.2) SUBSYSTEM: Glutathione Metabolism
reversible: true
name: glutathioneperidoxase
reactant: 308209
product: 308233
kinetic law: 308257
reactant: 308221
fast: false

308245
type: SpeciesReference
stoichiometry: 2.0
species: 378059

308209
type: SpeciesReference
stoichiometry: 2.0
species: 378017

308233
type: SpeciesReference
stoichiometry: 1.0
species: 378011

380634
type: LocalParameter
units: 304591
value: 0.0

380631
type: LocalParameter
units: 304591
value: 0.0

380628
type: LocalParameter
units: 304591
value: 1000.0

380625
type: LocalParameter
units: 304591
value: -1000.0

308221
type: SpeciesReference
stoichiometry: 1.0
species: 378047

379870
type: Reaction
kinetic law: 326599
reactant: 326587
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Adenineexchange

383262
type: LocalParameter
units: 304591
value: 0.0

383261
type: LocalParameter
units: 304591
value: 0.0

383260
type: LocalParameter
units: 304591
value: 13.5135135135135

383259
type: LocalParameter
units: 304591
value: -1000.0

326587
type: SpeciesReference
stoichiometry: 1.0
species: 377691

379668
type: Reaction
kinetic law: 324959
reactant: 324947
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382990
type: LocalParameter
units: 304591
value: 0.0

382989
type: LocalParameter
units: 304591
value: 0.0

382988
type: LocalParameter
units: 304591
value: 13.5135135135135

382987
type: LocalParameter
units: 304591
value: 0.0

324947
type: SpeciesReference
stoichiometry: 1.0
species: 377951

379885
type: Reaction
kinetic law: 326721
reactant: 326709
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Glutamineexchange

383282
type: LocalParameter
units: 304591
value: 0.0

383281
type: LocalParameter
units: 304591
value: 0.0

383280
type: LocalParameter
units: 304591
value: 0.0

383279
type: LocalParameter
units: 304591
value: -1000.0

326709
type: SpeciesReference
stoichiometry: 1.0
species: 377969

378732
type: Reaction
name: aldehydedehydrogenase(acetylaldehyde,NAD),mitochondrial
kinetic law: 307715
product: 307703
product: 307691
reactant: 307654
product: 307679
notes: GENE_ASSOCIATION: (217.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
reactant: 307666
fast: false
reactant: 307642
reversible: false

380524
type: LocalParameter
units: 304591
value: 0.0

380521
type: LocalParameter
units: 304591
value: 0.0

380518
type: LocalParameter
units: 304591
value: 1000.0

380515
type: LocalParameter
units: 304591
value: 0.0

307703
type: SpeciesReference
stoichiometry: 1.0
species: 378221

307691
type: SpeciesReference
stoichiometry: 2.0
species: 378083

307654
type: SpeciesReference
stoichiometry: 1.0
species: 378065

307679
type: SpeciesReference
stoichiometry: 1.0
species: 377658

307666
type: SpeciesReference
stoichiometry: 1.0
species: 378215

307642
type: SpeciesReference
stoichiometry: 1.0
species: 377667

379353
type: Reaction
kinetic law: 319881
product: 319869
product: 319857
reactant: 319845
notes: GENE_ASSOCIATION: SUBSYSTEM: Pyruvate Metabolism
fast: false
reversible: false
name: methyglyoxylatesynthase2(fromg3p)

382293
type: LocalParameter
units: 304591
value: 0.0

382291
type: LocalParameter
units: 304591
value: 0.0

382289
type: LocalParameter
units: 304591
value: 1000.0

382287
type: LocalParameter
units: 304591
value: 0.0

319869
type: SpeciesReference
stoichiometry: 1.0
species: 378338

319857
type: SpeciesReference
stoichiometry: 1.0
species: 378200

319845
type: SpeciesReference
stoichiometry: 1.0
species: 377933

379368
type: Reaction
reactant: 320159
notes: GENE_ASSOCIATION: (128.1) SUBSYSTEM: Pyruvate Metabolism
reversible: false
reactant: 320147
product: 320183
product: 320171
name: alcoholdehydrogenase(L-1,2-propanediol)
fast: false
kinetic law: 320208
product: 320195

320159
type: SpeciesReference
stoichiometry: 1.0
species: 378212

320147
type: SpeciesReference
stoichiometry: 1.0
species: 377565

320183
type: SpeciesReference
stoichiometry: 1.0
species: 378155

320171
type: SpeciesReference
stoichiometry: 1.0
species: 378077

382328
type: LocalParameter
units: 304591
value: 0.0

382326
type: LocalParameter
units: 304591
value: 0.0

382324
type: LocalParameter
units: 304591
value: 1000.0

382322
type: LocalParameter
units: 304591
value: 0.0

320195
type: SpeciesReference
stoichiometry: 1.0
species: 378218

379032
type: Reaction
reversible: true
name: glutathioneperoxidase(e)
product: 313839
reactant: 313827
product: 313851
kinetic law: 313863
reactant: 313815
fast: false
notes: GENE_ASSOCIATION: (2878.1) SUBSYSTEM: Glutathione Metabolism

313839
type: SpeciesReference
stoichiometry: 1.0
species: 378014

313827
type: SpeciesReference
stoichiometry: 1.0
species: 378050

313851
type: SpeciesReference
stoichiometry: 2.0
species: 378062

381524
type: LocalParameter
units: 304591
value: 0.0

381521
type: LocalParameter
units: 304591
value: 0.0

381518
type: LocalParameter
units: 304591
value: 1000.0

381515
type: LocalParameter
units: 304591
value: -1000.0

313815
type: SpeciesReference
stoichiometry: 2.0
species: 378020

377742
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: arachidonic acid

378963
type: Reaction
product: 312352
reactant: 312340
reversible: true
kinetic law: 312389
notes: GENE_ASSOCIATION: (3418.1) SUBSYSTEM: Citric Acid Cycle
reactant: 312328
name: Isocitratedehydrogenase(NADP+)
fast: false
product: 312364
product: 312376

312352
type: SpeciesReference
stoichiometry: 1.0
species: 377715

312340
type: SpeciesReference
stoichiometry: 1.0
species: 378230

381294
type: LocalParameter
units: 304591
value: 0.0

381291
type: LocalParameter
units: 304591
value: 0.0

381288
type: LocalParameter
units: 304591
value: 1000.0

381285
type: LocalParameter
units: 304591
value: -1000.0

312328
type: SpeciesReference
stoichiometry: 1.0
species: 378119

312364
type: SpeciesReference
stoichiometry: 1.0
species: 377823

312376
type: SpeciesReference
stoichiometry: 1.0
species: 378239

378597
type: Reaction
kinetic law: 305085
product: 305073
reactant: 305061
notes: GENE_ASSOCIATION: (5223.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
reversible: true
name: phosphoglyceratemutase

379980
type: LocalParameter
units: 304591
value: 0.0

379977
type: LocalParameter
units: 304591
value: 0.0

379974
type: LocalParameter
units: 304591
value: 1000.0

379971
type: LocalParameter
units: 304591
value: -1000.0

305073
type: SpeciesReference
stoichiometry: 1.0
species: 377616

305061
type: SpeciesReference
stoichiometry: 1.0
species: 377610

378116
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Hypoxanthine

378311
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: phosphatidylinositol 4,5-bisphosphate (Homo sapiens)

379263
type: Reaction
product: 318264
product: 318276
notes: GENE_ASSOCIATION: (11001.1) SUBSYSTEM: Transport, Extracellular
name: fattyacidelectroneutraltransport
fast: false
reversible: true
reactant: 318240
kinetic law: 318288
reactant: 318252

318264
type: SpeciesReference
stoichiometry: 1.0
species: 377709

318276
type: SpeciesReference
stoichiometry: 1.0
species: 378209

318240
type: SpeciesReference
stoichiometry: 1.0
species: 377706

382083
type: LocalParameter
units: 304591
value: 0.0

382081
type: LocalParameter
units: 304591
value: 0.0

382079
type: LocalParameter
units: 304591
value: 1000.0

382077
type: LocalParameter
units: 304591
value: -1000.0

318252
type: SpeciesReference
stoichiometry: 1.0
species: 378206

379647
type: Reaction
kinetic law: 324791
reactant: 324779
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382962
type: LocalParameter
units: 304591
value: 0.0

382961
type: LocalParameter
units: 304591
value: 0.0

382960
type: LocalParameter
units: 304591
value: 13.5135135135135

382959
type: LocalParameter
units: 304591
value: 0.0

324779
type: SpeciesReference
stoichiometry: 1.0
species: 377978

378711
type: Reaction
kinetic law: 307281
product: 307269
reactant: 307257
reactant: 307245
notes: GENE_ASSOCIATION: (771.1) or (771.2) or (760.1) SUBSYSTEM: Miscellaneous
fast: false
reversible: true
name: carboxylicaciddissociation

380454
type: LocalParameter
units: 304591
value: 0.0

380451
type: LocalParameter
units: 304591
value: 0.0

380448
type: LocalParameter
units: 304591
value: 1000.0

380445
type: LocalParameter
units: 304591
value: -1000.0

307269
type: SpeciesReference
stoichiometry: 1.0
species: 378044

307257
type: SpeciesReference
stoichiometry: 1.0
species: 378059

307245
type: SpeciesReference
stoichiometry: 1.0
species: 377817

379011
type: Reaction
kinetic law: 313392
product: 313380
reversible: false
product: 313368
reactant: 313344
notes: GENE_ASSOCIATION: (4907.1) SUBSYSTEM: Nucleotides
reactant: 313356
name: 5'-nucleotidase(AMP),extracellular
fast: false

381454
type: LocalParameter
units: 304591
value: 0.0

381451
type: LocalParameter
units: 304591
value: 0.0

381448
type: LocalParameter
units: 304591
value: 1000.0

381445
type: LocalParameter
units: 304591
value: 0.0

313380
type: SpeciesReference
stoichiometry: 1.0
species: 378341

313368
type: SpeciesReference
stoichiometry: 1.0
species: 377697

313344
type: SpeciesReference
stoichiometry: 1.0
species: 377733

377733
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: AMP

313356
type: SpeciesReference
stoichiometry: 1.0
species: 378062

378654
type: Reaction
kinetic law: 306204
reversible: true
fast: false
product: 306192
reactant: 306156
reactant: 306168
notes: GENE_ASSOCIATION: (4832.1) SUBSYSTEM: Nucleotides
name: nucleoside-diphosphatekinase(ATP:GDP)
product: 306180

380170
type: LocalParameter
units: 304591
value: 0.0

380167
type: LocalParameter
units: 304591
value: 0.0

380164
type: LocalParameter
units: 304591
value: 1000.0

380161
type: LocalParameter
units: 304591
value: -1000.0

306192
type: SpeciesReference
stoichiometry: 1.0
species: 378023

306156
type: SpeciesReference
stoichiometry: 1.0
species: 377769

306168
type: SpeciesReference
stoichiometry: 1.0
species: 377939

306180
type: SpeciesReference
stoichiometry: 1.0
species: 377700

379095
type: Reaction
name: L-cysteine/glycineexchanger
product: 315134
reactant: 315098
fast: false
reversible: false
notes: GENE_ASSOCIATION: (6520.1) and (23428.1) or (6520.1) and (23428.2) SUBSYSTEM: Transport, Extracellular
product: 315122
reactant: 315110
kinetic law: 315146

315134
type: SpeciesReference
stoichiometry: 1.0
species: 377993

315098
type: SpeciesReference
stoichiometry: 1.0
species: 377850

315122
type: SpeciesReference
stoichiometry: 1.0
species: 377853

315110
type: SpeciesReference
stoichiometry: 1.0
species: 377996

381692
type: LocalParameter
units: 304591
value: 0.0

381690
type: LocalParameter
units: 304591
value: 0.0

381688
type: LocalParameter
units: 304591
value: 1000.0

381686
type: LocalParameter
units: 304591
value: 0.0

378942
type: Reaction
product: 312026
reactant: 311989
reversible: false
kinetic law: 312038
reactant: 311977
product: 312014
reactant: 312002
name: Propane-1,2-diol:NADP+1-oxidoreductase
notes: GENE_ASSOCIATION: (8574.1) or (231.1) or (10327.2) or (10327.1) SUBSYSTEM: Pyruvate Metabolism
fast: false

312026
type: SpeciesReference
stoichiometry: 1.0
species: 378227

311989
type: SpeciesReference
stoichiometry: 1.0
species: 378152

381224
type: LocalParameter
units: 304591
value: 0.0

381221
type: LocalParameter
units: 304591
value: 0.0

381218
type: LocalParameter
units: 304591
value: 1000.0

381215
type: LocalParameter
units: 304591
value: 0.0

311977
type: SpeciesReference
stoichiometry: 1.0
species: 378077

312014
type: SpeciesReference
stoichiometry: 1.0
species: 377562

312002
type: SpeciesReference
stoichiometry: 1.0
species: 378236

379242
type: Reaction
kinetic law: 317987
product: 317975
reactant: 317963
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: fattyacidtransportviadiffusion

382034
type: LocalParameter
units: 304591
value: 0.0

382032
type: LocalParameter
units: 304591
value: 0.0

382030
type: LocalParameter
units: 304591
value: 1000.0

382028
type: LocalParameter
units: 304591
value: -1000.0

317975
type: SpeciesReference
stoichiometry: 1.0
species: 377739

317963
type: SpeciesReference
stoichiometry: 1.0
species: 377742

379257
type: Reaction
product: 318180
fast: false
product: 318168
kinetic law: 318192
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
reactant: 318144
name: L-lactatereversibletransportviasodiumsymport
reversible: true
reactant: 318156

318180
type: SpeciesReference
stoichiometry: 1.0
species: 378206

318168
type: SpeciesReference
stoichiometry: 1.0
species: 378146

382069
type: LocalParameter
units: 304591
value: 0.0

382067
type: LocalParameter
units: 304591
value: 0.0

382065
type: LocalParameter
units: 304591
value: 1000.0

382063
type: LocalParameter
units: 304591
value: -1000.0

318144
type: SpeciesReference
stoichiometry: 1.0
species: 378149

318156
type: SpeciesReference
stoichiometry: 1.0
species: 378209

379572
type: Reaction
kinetic law: 323596
product: 323584
reactant: 323572
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true

382819
type: LocalParameter
units: 304591
value: 0.0

382817
type: LocalParameter
units: 304591
value: 0.0

382815
type: LocalParameter
units: 304591
value: 1000.0

382813
type: LocalParameter
units: 304591
value: -1000.0

323584
type: SpeciesReference
stoichiometry: 1.0
species: 377790

323572
type: SpeciesReference
stoichiometry: 1.0
species: 378575

378726
type: Reaction
kinetic law: 307594
product: 307582
reactant: 307570
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: CO2transporterviadiffusion

380504
type: LocalParameter
units: 304591
value: 0.0

380501
type: LocalParameter
units: 304591
value: 0.0

380498
type: LocalParameter
units: 304591
value: 1000.0

380495
type: LocalParameter
units: 304591
value: -1000.0

307582
type: SpeciesReference
stoichiometry: 1.0
species: 377817

307570
type: SpeciesReference
stoichiometry: 1.0
species: 377820

377799
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: Choline

379488
type: Reaction
kinetic law: 322371
product: 322359
reactant: 322347
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: phosphatetransport,nuclear

382623
type: LocalParameter
units: 304591
value: 0.0

382621
type: LocalParameter
units: 304591
value: 0.0

382619
type: LocalParameter
units: 304591
value: 1000.0

382617
type: LocalParameter
units: 304591
value: -1000.0

322359
type: SpeciesReference
stoichiometry: 1.0
species: 378338

322347
type: SpeciesReference
stoichiometry: 1.0
species: 378347

379494
type: Reaction
kinetic law: 322444
product: 322431
reactant: 322419
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: Cholinetransport,nuclearthroughpores

382637
type: LocalParameter
units: 304591
value: 0.0

382635
type: LocalParameter
units: 304591
value: 0.0

382633
type: LocalParameter
units: 304591
value: 1000.0

382631
type: LocalParameter
units: 304591
value: -1000.0

322431
type: SpeciesReference
stoichiometry: 1.0
species: 377799

322419
type: SpeciesReference
stoichiometry: 1.0
species: 377793

379746
type: Reaction
kinetic law: 325588
reactant: 325576
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Pyridoxalexchange

383094
type: LocalParameter
units: 304591
value: 0.0

383093
type: LocalParameter
units: 304591
value: 0.0

383092
type: LocalParameter
units: 304591
value: 13.5135135135135

383091
type: LocalParameter
units: 304591
value: -1000.0

325576
type: SpeciesReference
stoichiometry: 1.0
species: 378401

378401
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Pyridoxal

379752
type: Reaction
kinetic law: 325636
reactant: 325624
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Chlorideexchange

383102
type: LocalParameter
units: 304591
value: 0.0

383101
type: LocalParameter
units: 304591
value: 0.0

383100
type: LocalParameter
units: 304591
value: 0.0

383099
type: LocalParameter
units: 304591
value: -1000.0

325624
type: SpeciesReference
stoichiometry: 1.0
species: 377814

379518
type: Reaction
kinetic law: 322781
product: 322769
reactant: 322757
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: sphinganineintracellulartransport

382693
type: LocalParameter
units: 304591
value: 0.0

382691
type: LocalParameter
units: 304591
value: 0.0

382689
type: LocalParameter
units: 304591
value: 1000.0

382687
type: LocalParameter
units: 304591
value: -1000.0

322769
type: SpeciesReference
stoichiometry: 1.0
species: 378467

322757
type: SpeciesReference
stoichiometry: 1.0
species: 378470

378669
type: Reaction
reactant: 306469
reversible: true
kinetic law: 306505
product: 306493
product: 306481
reactant: 306457
fast: false
name: purine-nucleosidephosphorylase(Deoxyinosine)
notes: GENE_ASSOCIATION: (4860.1) SUBSYSTEM: Purine Catabolism

306469
type: SpeciesReference
stoichiometry: 1.0
species: 378338

380314
type: LocalParameter
units: 304591
value: 0.0

380311
type: LocalParameter
units: 304591
value: 0.0

380308
type: LocalParameter
units: 304591
value: 1000.0

380305
type: LocalParameter
units: 304591
value: -1000.0

306493
type: SpeciesReference
stoichiometry: 1.0
species: 378116

306481
type: SpeciesReference
stoichiometry: 1.0
species: 377604

306457
type: SpeciesReference
stoichiometry: 1.0
species: 377877

379731
type: Reaction
kinetic law: 325467
reactant: 325455
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Methylglyoxalexchange

383074
type: LocalParameter
units: 304591
value: 0.0

383073
type: LocalParameter
units: 304591
value: 0.0

383072
type: LocalParameter
units: 304591
value: 13.5135135135135

383071
type: LocalParameter
units: 304591
value: -1000.0

325455
type: SpeciesReference
stoichiometry: 1.0
species: 378203

378624
type: Reaction
reactant: 305510
product: 305559
name: L-lactatedehydrogenase
kinetic law: 305571
reversible: true
product: 305535
notes: GENE_ASSOCIATION: (3945.1) or (3945.1 and 3939.1) or (3939.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
product: 305547
reactant: 305523
fast: false

305510
type: SpeciesReference
stoichiometry: 1.0
species: 378146

305559
type: SpeciesReference
stoichiometry: 1.0
species: 378404

380070
type: LocalParameter
units: 304591
value: 0.0

380067
type: LocalParameter
units: 304591
value: 0.0

380064
type: LocalParameter
units: 304591
value: 1000.0

380061
type: LocalParameter
units: 304591
value: -1000.0

305535
type: SpeciesReference
stoichiometry: 1.0
species: 378077

305547
type: SpeciesReference
stoichiometry: 1.0
species: 378218

305523
type: SpeciesReference
stoichiometry: 1.0
species: 378212

378813
type: Reaction
kinetic law: 309126
product: 309114
reactant: 309102
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: O2transport,endoplasmicreticulum

380794
type: LocalParameter
units: 304591
value: 0.0

380791
type: LocalParameter
units: 304591
value: 0.0

380788
type: LocalParameter
units: 304591
value: 1000.0

380785
type: LocalParameter
units: 304591
value: -1000.0

309114
type: SpeciesReference
stoichiometry: 1.0
species: 378275

309102
type: SpeciesReference
stoichiometry: 1.0
species: 378266

379155
type: Reaction
notes: GENE_ASSOCIATION: (1103.4) or (1103.1) or (1103.3) or (1103.2) SUBSYSTEM: Glycerophospholipid Metabolism
product: 316429
product: 316417
kinetic law: 316441
name: CholineO-acetyltransferase
fast: false
reactant: 316405
reactant: 316393
reversible: true

316429
type: SpeciesReference
stoichiometry: 1.0
species: 377832

316417
type: SpeciesReference
stoichiometry: 1.0
species: 377685

381831
type: LocalParameter
units: 304591
value: 0.0

381829
type: LocalParameter
units: 304591
value: 0.0

381827
type: LocalParameter
units: 304591
value: 1000.0

381825
type: LocalParameter
units: 304591
value: -1000.0

316405
type: SpeciesReference
stoichiometry: 1.0
species: 377799

316393
type: SpeciesReference
stoichiometry: 1.0
species: 377676

377676
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: Acetyl-CoA

379203
type: Reaction
kinetic law: 317249
reactant: 317189
name: xanthineoxidase,peroxisomal
product: 317225
fast: false
reactant: 317213
reactant: 317201
product: 317237
notes: GENE_ASSOCIATION: (7498.1) SUBSYSTEM: Purine Catabolism
reversible: false

381943
type: LocalParameter
units: 304591
value: 0.0

381941
type: LocalParameter
units: 304591
value: 0.0

381939
type: LocalParameter
units: 304591
value: 1000.0

381937
type: LocalParameter
units: 304591
value: 0.0

317189
type: SpeciesReference
stoichiometry: 1.0
species: 378074

317225
type: SpeciesReference
stoichiometry: 1.0
species: 378056

317213
type: SpeciesReference
stoichiometry: 1.0
species: 378545

317201
type: SpeciesReference
stoichiometry: 1.0
species: 378278

317237
type: SpeciesReference
stoichiometry: 1.0
species: 378527

378167
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: lignoceric acid

379578
type: Reaction
product: 324188
product: 324006
product: 323801
product: 324224
product: 324164
product: 323897
reactant: 323752
reactant: 323716
product: 323958
product: 324068
product: 324200
reactant: 323740
product: 324092
reactant: 323704
product: 324140
fast: false
product: 323873
reactant: 323728
product: 324018
product: 323909
product: 324116
product: 323921
notes: GENE_ASSOCIATION: SUBSYSTEM:
product: 323837
product: 324043
product: 323970
product: 323982
product: 323813
product: 324212
product: 323885
product: 324176
reactant: 323776
reversible: false
reactant: 323692
product: 323933
product: 323861
reactant: 323764
product: 324152
reactant: 323680
product: 323946
product: 324080
product: 324128
kinetic law: 324236
product: 323849
product: 324055
product: 323788
product: 324104
product: 323994
product: 323825
product: 324031

324188
type: SpeciesReference
stoichiometry: 1.0
species: 378509

324006
type: SpeciesReference
stoichiometry: 1.0
species: 378095

323801
type: SpeciesReference
stoichiometry: 1.0
species: 377700

324224
type: SpeciesReference
stoichiometry: 1.0
species: 378575

324164
type: SpeciesReference
stoichiometry: 1.0
species: 378458

323897
type: SpeciesReference
stoichiometry: 1.0
species: 377853

323752
type: SpeciesReference
stoichiometry: 1.0
species: 378530

323716
type: SpeciesReference
stoichiometry: 1.0
species: 378386

323958
type: SpeciesReference
stoichiometry: 1.0
species: 378020

324068
type: SpeciesReference
stoichiometry: 1.0
species: 378176

324200
type: SpeciesReference
stoichiometry: 1.0
species: 378518

323740
type: SpeciesReference
stoichiometry: 1.0
species: 378521

324092
type: SpeciesReference
stoichiometry: 1.0
species: 378209

323704
type: SpeciesReference
stoichiometry: 1.0
species: 378059

324140
type: SpeciesReference
stoichiometry: 1.0
species: 378341

323873
type: SpeciesReference
stoichiometry: 1.0
species: 377805

323728
type: SpeciesReference
stoichiometry: 1.0
species: 378512

324018
type: SpeciesReference
stoichiometry: 1.0
species: 378107

323909
type: SpeciesReference
stoichiometry: 1.0
species: 377954

324116
type: SpeciesReference
stoichiometry: 1.0
species: 378335

323921
type: SpeciesReference
stoichiometry: 1.0
species: 377969

323837
type: SpeciesReference
stoichiometry: 1.0
species: 377760

324043
type: SpeciesReference
stoichiometry: 1.0
species: 378143

323970
type: SpeciesReference
stoichiometry: 1.0
species: 378062

323982
type: SpeciesReference
stoichiometry: 1.0
species: 378077

323813
type: SpeciesReference
stoichiometry: 1.0
species: 377727

324212
type: SpeciesReference
stoichiometry: 1.0
species: 378539

323885
type: SpeciesReference
stoichiometry: 1.0
species: 377814

324176
type: SpeciesReference
stoichiometry: 1.0
species: 378503

323776
type: SpeciesReference
stoichiometry: 1.0
species: 378569

323692
type: SpeciesReference
stoichiometry: 1.0
species: 377787

323933
type: SpeciesReference
stoichiometry: 1.0
species: 377981

323861
type: SpeciesReference
stoichiometry: 1.0
species: 377784

323764
type: SpeciesReference
stoichiometry: 1.0
species: 378563

324152
type: SpeciesReference
stoichiometry: 1.0
species: 378380

323680
type: SpeciesReference
stoichiometry: 1.0
species: 377769

323946
type: SpeciesReference
stoichiometry: 1.0
species: 377996

324080
type: SpeciesReference
stoichiometry: 1.0
species: 378191

324128
type: SpeciesReference
stoichiometry: 1.0
species: 378338

382833
type: LocalParameter
units: 304591
value: 1.0

382831
type: LocalParameter
units: 304591
value: 0.0

382829
type: LocalParameter
units: 304591
value: 1000.0

382827
type: LocalParameter
units: 304591
value: 0.0

323849
type: SpeciesReference
stoichiometry: 1.0
species: 377766

324055
type: SpeciesReference
stoichiometry: 1.0
species: 378161

323788
type: SpeciesReference
stoichiometry: 1.0
species: 377655

324104
type: SpeciesReference
stoichiometry: 1.0
species: 378302

323994
type: SpeciesReference
stoichiometry: 1.0
species: 378080

323825
type: SpeciesReference
stoichiometry: 1.0
species: 377751

324031
type: SpeciesReference
stoichiometry: 1.0
species: 378125

379434
type: Reaction
kinetic law: 321475
product: 321463
reactant: 321451
reactant: 321439
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
fast: false
reversible: false
name: 13-cis-4-oxo-retinoicacidformation(oxidation)

382482
type: LocalParameter
units: 304591
value: 0.0

382480
type: LocalParameter
units: 304591
value: 0.0

382478
type: LocalParameter
units: 304591
value: 1000.0

382476
type: LocalParameter
units: 304591
value: 0.0

321463
type: SpeciesReference
stoichiometry: 2.0
species: 377568

321451
type: SpeciesReference
stoichiometry: 1.0
species: 378266

321439
type: SpeciesReference
stoichiometry: 2.0
species: 377574

379449
type: Reaction
kinetic law: 321656
product: 321643
reactant: 321631
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: false
name: NADHtransporter,peroxisome

382517
type: LocalParameter
units: 304591
value: 0.0

382515
type: LocalParameter
units: 304591
value: 0.0

382513
type: LocalParameter
units: 304591
value: 1000.0

382511
type: LocalParameter
units: 304591
value: 0.0

321643
type: SpeciesReference
stoichiometry: 1.0
species: 378224

321631
type: SpeciesReference
stoichiometry: 1.0
species: 378218

379638
type: Reaction
kinetic law: 324719
reactant: 324707
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382950
type: LocalParameter
units: 304591
value: 0.0

382949
type: LocalParameter
units: 304591
value: 0.0

382948
type: LocalParameter
units: 304591
value: 13.5135135135135

382947
type: LocalParameter
units: 304591
value: 0.0

324707
type: SpeciesReference
stoichiometry: 1.0
species: 378122

378744
type: Reaction
name: ribosetransportinviaprotonsymporter
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
reversible: false
fast: false
reactant: 307836
product: 307860
product: 307872
kinetic law: 307884
reactant: 307848

307836
type: SpeciesReference
stoichiometry: 1.0
species: 378080

307860
type: SpeciesReference
stoichiometry: 1.0
species: 378077

307872
type: SpeciesReference
stoichiometry: 1.0
species: 378434

380564
type: LocalParameter
units: 304591
value: 0.0

380561
type: LocalParameter
units: 304591
value: 0.0

380558
type: LocalParameter
units: 304591
value: 1000.0

380555
type: LocalParameter
units: 304591
value: 0.0

307848
type: SpeciesReference
stoichiometry: 1.0
species: 378437

379044
type: Reaction
kinetic law: 314103
product: 314091
reactant: 314079
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: pyridoxaltransportviadiffusion

381564
type: LocalParameter
units: 304591
value: 0.0

381561
type: LocalParameter
units: 304591
value: 0.0

381558
type: LocalParameter
units: 304591
value: 1000.0

381555
type: LocalParameter
units: 304591
value: -1000.0

314091
type: SpeciesReference
stoichiometry: 1.0
species: 378398

314079
type: SpeciesReference
stoichiometry: 1.0
species: 378401

379050
type: Reaction
product: 314263
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
kinetic law: 314276
reactant: 314187
fast: false
name: 4-Pyridoxalsecretion
product: 314237
reactant: 314199
reversible: false
product: 314224
reactant: 314211
product: 314250

314263
type: SpeciesReference
stoichiometry: 1.0
species: 378338

381581
type: LocalParameter
units: 304591
value: 0.0

381579
type: LocalParameter
units: 304591
value: 0.0

381576
type: LocalParameter
units: 304591
value: 1000.0

381574
type: LocalParameter
units: 304591
value: 0.0

314187
type: SpeciesReference
stoichiometry: 1.0
species: 377628

314237
type: SpeciesReference
stoichiometry: 1.0
species: 377700

314199
type: SpeciesReference
stoichiometry: 1.0
species: 377769

314224
type: SpeciesReference
stoichiometry: 1.0
species: 377631

314211
type: SpeciesReference
stoichiometry: 1.0
species: 378059

314250
type: SpeciesReference
stoichiometry: 1.0
species: 378077

378891
type: Reaction
notes: GENE_ASSOCIATION: (498.2 and 509.1 and 513.2 and 506.1 and 514.1 or 513.1 and 506.1 and 498.3 and 509.2 and 514.1 or 513.2 and 498.1 and 506.1 and 509.2 and 514.1 or 513.1 and 509.1 and 506.1 and 498.3 and 514.1 or 513.1 and 509.1 and 498.1 and 514.2 and 506.1 or 513.1 and 514.2 and 506.1 and 498.3 and 509.2 or 513.1 and 509.1 and 498.1 and 506.1 and 514.1 or 513.1 and 509.1 and 514.2 and 506.1 and 498.3 or 513.2 and 506.1 and 498.3 and 509.2 and 514.1 or 498.2 and 513.2 and 514.2 and 506.1 and 509.2 or 513.1 and 498.2 and 506.1 and 509.2 and 514.1 or 513.1 and 498.1 and 514.2 and 506.1 and 509.2 or 509.1 and 513.2 and 498.1 and 506.1 and 514.1 or 513.1 and 498.2 and 509.1 and 506.1 and 514.1 or 498.2 and 509.1 and 513.2 and 514.2 and 506.1 or 509.1 and 513.2 and 514.2 and 506.1 and 498.3 or 513.1 and 498.2 and 514.2 and 506.1 and 509.2 or 498.2 and 513.2 and 506.1 and 509.2 and 514.1 or 513.2 and 498.1 and 514.2 and 506.1 and 509.2 or 509.1 and 513.2 and 498.1 and 514.2 and 506.1 or 513.2 and 514.2 and 506.1 and 498.3 and 509.2 or 509.1 and 513.2 and 506.1 and 498.3 and 514.1 or 513.1 and 498.2 and 509.1 and 514.2 and 506.1) SUBSYSTEM: Oxidative Phosphorylation
product: 310828
kinetic law: 310840
reactant: 310779
reactant: 310767
fast: false
reversible: false
reactant: 310791
product: 310816
name: ATPsynthase(fourprotonsforoneATP)
product: 310803

310828
type: SpeciesReference
stoichiometry: 3.0
species: 378083

381054
type: LocalParameter
units: 304591
value: 0.0

381051
type: LocalParameter
units: 304591
value: 0.0

381048
type: LocalParameter
units: 304591
value: 1000.0

381045
type: LocalParameter
units: 304591
value: 0.0

310779
type: SpeciesReference
stoichiometry: 4.0
species: 378077

310767
type: SpeciesReference
stoichiometry: 1.0
species: 377703

310791
type: SpeciesReference
stoichiometry: 1.0
species: 378344

310816
type: SpeciesReference
stoichiometry: 1.0
species: 378065

310803
type: SpeciesReference
stoichiometry: 1.0
species: 377772

378777
type: Reaction
product: 308449
product: 308437
name: L-4-hydroxyglutamatesemialdehydedehydrogenase,mitochondrial
fast: false
reactant: 308401
notes: GENE_ASSOCIATION: (8659.1) or (8659.2) SUBSYSTEM: Arginine and Proline Metabolism
reactant: 308413
product: 308461
kinetic law: 308473
reactant: 308425
reversible: true

308449
type: SpeciesReference
stoichiometry: 2.0
species: 378083

308437
type: SpeciesReference
stoichiometry: 1.0
species: 377889

308401
type: SpeciesReference
stoichiometry: 1.0
species: 377625

308413
type: SpeciesReference
stoichiometry: 1.0
species: 378065

308461
type: SpeciesReference
stoichiometry: 1.0
species: 378221

380674
type: LocalParameter
units: 304591
value: 0.0

380671
type: LocalParameter
units: 304591
value: 0.0

380668
type: LocalParameter
units: 304591
value: 1000.0

380665
type: LocalParameter
units: 304591
value: -1000.0

308425
type: SpeciesReference
stoichiometry: 1.0
species: 378215

378723
type: Reaction
fast: false
reactant: 307510
notes: GENE_ASSOCIATION: (2571.1) or (2571.2) SUBSYSTEM: Glutamate metabolism
name: GlutamateDecarboxylase
kinetic law: 307558
reversible: false
reactant: 307522
product: 307534
product: 307546

307510
type: SpeciesReference
stoichiometry: 1.0
species: 377978

380494
type: LocalParameter
units: 304591
value: 0.0

380491
type: LocalParameter
units: 304591
value: 0.0

380488
type: LocalParameter
units: 304591
value: 1000.0

380485
type: LocalParameter
units: 304591
value: 0.0

307522
type: SpeciesReference
stoichiometry: 1.0
species: 378077

307534
type: SpeciesReference
stoichiometry: 1.0
species: 377619

307546
type: SpeciesReference
stoichiometry: 1.0
species: 377817

379701
type: Reaction
kinetic law: 325225
reactant: 325212
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

383034
type: LocalParameter
units: 304591
value: 0.0

383033
type: LocalParameter
units: 304591
value: 0.0

383032
type: LocalParameter
units: 304591
value: 13.5135135135135

383031
type: LocalParameter
units: 304591
value: 0.0

325212
type: SpeciesReference
stoichiometry: 1.0
species: 378206

379521
type: Reaction
product: 322853
product: 322841
fast: false
reactant: 322793
notes: GENE_ASSOCIATION: (4363.1) SUBSYSTEM: Transport, Extracellular
kinetic law: 322877
product: 322829
reactant: 322805
reactant: 322817
name: bilirubinmonoglucuronidetransportMDR
product: 322865
reversible: true

322853
type: SpeciesReference
stoichiometry: 1.0
species: 378077

322841
type: SpeciesReference
stoichiometry: 1.0
species: 377778

322793
type: SpeciesReference
stoichiometry: 1.0
species: 377769

382700
type: LocalParameter
units: 304591
value: 0.0

382698
type: LocalParameter
units: 304591
value: 0.0

382696
type: LocalParameter
units: 304591
value: 0.0

382694
type: LocalParameter
units: 304591
value: -1000.0

322829
type: SpeciesReference
stoichiometry: 1.0
species: 377700

322805
type: SpeciesReference
stoichiometry: 1.0
species: 377775

322817
type: SpeciesReference
stoichiometry: 1.0
species: 378059

322865
type: SpeciesReference
stoichiometry: 1.0
species: 378338

379023
type: Reaction
notes: GENE_ASSOCIATION: (8396.1) or (8396.2) SUBSYSTEM: Glycerophospholipid Metabolism
fast: false
product: 313646
name: phosphatidylinositol4-phosphate5-kinase
product: 313634
reactant: 313610
reversible: false
kinetic law: 313670
reactant: 313622
product: 313658

313646
type: SpeciesReference
stoichiometry: 1.0
species: 378077

313634
type: SpeciesReference
stoichiometry: 1.0
species: 377700

313610
type: SpeciesReference
stoichiometry: 1.0
species: 377769

381494
type: LocalParameter
units: 304591
value: 0.0

381491
type: LocalParameter
units: 304591
value: 0.0

381488
type: LocalParameter
units: 304591
value: 1000.0

381485
type: LocalParameter
units: 304591
value: 0.0

313622
type: SpeciesReference
stoichiometry: 1.0
species: 378314

313658
type: SpeciesReference
stoichiometry: 1.0
species: 378308

378933
type: Reaction
kinetic law: 311820
name: D-Lactaldehyde:NADP+1-oxidoreductase
reversible: false
reactant: 311772
reactant: 311760
fast: false
product: 311796
reactant: 311784
notes: GENE_ASSOCIATION: (10327.1) or (8574.1) or (10327.2) or (231.1) SUBSYSTEM: Pyruvate Metabolism
product: 311808

381194
type: LocalParameter
units: 304591
value: 0.0

381191
type: LocalParameter
units: 304591
value: 0.0

381188
type: LocalParameter
units: 304591
value: 1000.0

381185
type: LocalParameter
units: 304591
value: 0.0

311772
type: SpeciesReference
stoichiometry: 1.0
species: 378200

311760
type: SpeciesReference
stoichiometry: 1.0
species: 378077

311796
type: SpeciesReference
stoichiometry: 1.0
species: 378152

311784
type: SpeciesReference
stoichiometry: 1.0
species: 378236

311808
type: SpeciesReference
stoichiometry: 1.0
species: 378227

379398
type: Reaction
name: Aldosereductase
reactant: 320715
product: 320763
fast: false
reactant: 320739
product: 320751
reversible: false
kinetic law: 320787
reactant: 320727
product: 320775
notes: GENE_ASSOCIATION: (231.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism

320715
type: SpeciesReference
stoichiometry: 1.0
species: 378059

320763
type: SpeciesReference
stoichiometry: 1.0
species: 378236

320739
type: SpeciesReference
stoichiometry: 1.0
species: 378227

320751
type: SpeciesReference
stoichiometry: 2.0
species: 378077

382398
type: LocalParameter
units: 304591
value: 0.0

382396
type: LocalParameter
units: 304591
value: 0.0

382394
type: LocalParameter
units: 304591
value: 1000.0

382392
type: LocalParameter
units: 304591
value: 0.0

320727
type: SpeciesReference
stoichiometry: 1.0
species: 378200

320775
type: SpeciesReference
stoichiometry: 1.0
species: 378404

378672
type: Reaction
product: 306566
reversible: false
notes: GENE_ASSOCIATION: (5168.1) SUBSYSTEM: NAD Metabolism
name: DeaminidoNADdiphosphatase
reactant: 306530
product: 306554
product: 306542
fast: false
reactant: 306517
kinetic law: 306578

306566
type: SpeciesReference
stoichiometry: 1.0
species: 378257

306530
type: SpeciesReference
stoichiometry: 1.0
species: 378059

306554
type: SpeciesReference
stoichiometry: 2.0
species: 378077

306542
type: SpeciesReference
stoichiometry: 1.0
species: 377730

306517
type: SpeciesReference
stoichiometry: 1.0
species: 377883

380324
type: LocalParameter
units: 304591
value: 0.0

380321
type: LocalParameter
units: 304591
value: 0.0

380318
type: LocalParameter
units: 304591
value: 1000.0

380315
type: LocalParameter
units: 304591
value: 0.0

378687
type: Reaction
kinetic law: 306892
product: 306880
reactant: 306868
reactant: 306855
notes: GENE_ASSOCIATION: (2271.1) SUBSYSTEM: Citric Acid Cycle
fast: false
reversible: true
name: fumarase,mitochondrial

380374
type: LocalParameter
units: 304591
value: 0.0

380371
type: LocalParameter
units: 304591
value: 0.0

380368
type: LocalParameter
units: 304591
value: 1000.0

380365
type: LocalParameter
units: 304591
value: 0.0

306880
type: SpeciesReference
stoichiometry: 1.0
species: 378185

306868
type: SpeciesReference
stoichiometry: 1.0
species: 378065

306855
type: SpeciesReference
stoichiometry: 1.0
species: 377930

378975
type: Reaction
reactant: 312607
product: 312643
notes: GENE_ASSOCIATION: SUBSYSTEM: Pentose and Glucuronate Interconversions
product: 312655
product: 312631
kinetic law: 312667
reactant: 312619
name: xylitoldehydrogenase(D-xyulose-forming)
reversible: true
fast: false

312607
type: SpeciesReference
stoichiometry: 1.0
species: 378212

312643
type: SpeciesReference
stoichiometry: 1.0
species: 378218

312655
type: SpeciesReference
stoichiometry: 1.0
species: 378557

312631
type: SpeciesReference
stoichiometry: 1.0
species: 378077

381334
type: LocalParameter
units: 304591
value: 0.0

381331
type: LocalParameter
units: 304591
value: 0.0

381328
type: LocalParameter
units: 304591
value: 1000.0

381325
type: LocalParameter
units: 304591
value: -1000.0

312619
type: SpeciesReference
stoichiometry: 1.0
species: 378554

379260
type: Reaction
kinetic law: 318228
product: 318216
reactant: 318204
notes: GENE_ASSOCIATION: (3177.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: adeninereversibletransport,cytosol

382076
type: LocalParameter
units: 304591
value: 0.0

382074
type: LocalParameter
units: 304591
value: 0.0

382072
type: LocalParameter
units: 304591
value: 0.0

382070
type: LocalParameter
units: 304591
value: -1000.0

318216
type: SpeciesReference
stoichiometry: 1.0
species: 377688

318204
type: SpeciesReference
stoichiometry: 1.0
species: 377691

379269
type: Reaction
reactant: 318361
reactant: 318374
product: 318386
reversible: true
kinetic law: 318410
name: fattyacidelectroneutraltransport
notes: GENE_ASSOCIATION: (11001.1) SUBSYSTEM: Transport, Extracellular
fast: false
product: 318398

318361
type: SpeciesReference
stoichiometry: 1.0
species: 378164

318374
type: SpeciesReference
stoichiometry: 1.0
species: 378206

318386
type: SpeciesReference
stoichiometry: 1.0
species: 378167

382097
type: LocalParameter
units: 304591
value: 0.0

382095
type: LocalParameter
units: 304591
value: 0.0

382093
type: LocalParameter
units: 304591
value: 1000.0

382091
type: LocalParameter
units: 304591
value: -1000.0

318398
type: SpeciesReference
stoichiometry: 1.0
species: 378209

379275
type: Reaction
kinetic law: 318506
product: 318494
reactant: 318482
notes: GENE_ASSOCIATION: (117247.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: L-tyrosinetransport

382111
type: LocalParameter
units: 304591
value: 0.0

382109
type: LocalParameter
units: 304591
value: 0.0

382107
type: LocalParameter
units: 304591
value: 1000.0

382105
type: LocalParameter
units: 304591
value: 0.0

318494
type: SpeciesReference
stoichiometry: 1.0
species: 378515

318482
type: SpeciesReference
stoichiometry: 1.0
species: 378518

379590
type: Reaction
kinetic law: 324334
reactant: 324322
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382861
type: LocalParameter
units: 304591
value: 0.0

382859
type: LocalParameter
units: 304591
value: 0.0

382857
type: LocalParameter
units: 304591
value: 13.5135135135135

382855
type: LocalParameter
units: 304591
value: 0.0

324322
type: SpeciesReference
stoichiometry: 1.0
species: 378386

379500
type: Reaction
kinetic law: 322516
product: 322504
reactant: 322492
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: phosphatidylinositol4,5-bisphosphatenucleartransport(diffusion)

382651
type: LocalParameter
units: 304591
value: 0.0

382649
type: LocalParameter
units: 304591
value: 0.0

382647
type: LocalParameter
units: 304591
value: 1000.0

382645
type: LocalParameter
units: 304591
value: -1000.0

322504
type: SpeciesReference
stoichiometry: 1.0
species: 378311

322492
type: SpeciesReference
stoichiometry: 1.0
species: 378308

379764
type: Reaction
kinetic law: 325732
reactant: 325720
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: AMPexchange

383118
type: LocalParameter
units: 304591
value: 0.0

383117
type: LocalParameter
units: 304591
value: 0.0

383116
type: LocalParameter
units: 304591
value: 13.5135135135135

383115
type: LocalParameter
units: 304591
value: -1000.0

325720
type: SpeciesReference
stoichiometry: 1.0
species: 377733

378666
type: Reaction
reactant: 306408
reversible: true
fast: false
notes: GENE_ASSOCIATION: (4860.1) SUBSYSTEM: Purine Catabolism
product: 306420
reactant: 306396
kinetic law: 306444
name: purine-nucleosidephosphorylase(Inosine)
product: 306432

306408
type: SpeciesReference
stoichiometry: 1.0
species: 378338

306420
type: SpeciesReference
stoichiometry: 1.0
species: 378116

306396
type: SpeciesReference
stoichiometry: 1.0
species: 378134

380304
type: LocalParameter
units: 304591
value: 0.0

380301
type: LocalParameter
units: 304591
value: 0.0

380300
type: LocalParameter
units: 304591
value: 1000.0

380299
type: LocalParameter
units: 304591
value: -1000.0

306432
type: SpeciesReference
stoichiometry: 1.0
species: 378416

378954
type: Reaction
kinetic law: 312219
product: 312207
reactant: 312195
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: glucosetransport,endoplasmicreticulum

381264
type: LocalParameter
units: 304591
value: 0.0

381261
type: LocalParameter
units: 304591
value: 0.0

381258
type: LocalParameter
units: 304591
value: 1000.0

381255
type: LocalParameter
units: 304591
value: -1000.0

312207
type: SpeciesReference
stoichiometry: 1.0
species: 377957

312195
type: SpeciesReference
stoichiometry: 1.0
species: 377951

379254
type: Reaction
kinetic law: 318132
product: 318120
reactant: 318108
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: fattyacidtransportviadiffusion

382062
type: LocalParameter
units: 304591
value: 0.0

382060
type: LocalParameter
units: 304591
value: 0.0

382058
type: LocalParameter
units: 304591
value: 1000.0

382056
type: LocalParameter
units: 304591
value: -1000.0

318120
type: SpeciesReference
stoichiometry: 1.0
species: 378164

318108
type: SpeciesReference
stoichiometry: 1.0
species: 378167

379806
type: Reaction
kinetic law: 326069
reactant: 326057
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Adenosineexchange

383174
type: LocalParameter
units: 304591
value: 0.0

383173
type: LocalParameter
units: 304591
value: 0.0

383172
type: LocalParameter
units: 304591
value: 13.5135135135135

383171
type: LocalParameter
units: 304591
value: -1000.0

326057
type: SpeciesReference
stoichiometry: 1.0
species: 377697

379584
type: Reaction
kinetic law: 324286
reactant: 324273
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382847
type: LocalParameter
units: 304591
value: 0.0

382845
type: LocalParameter
units: 304591
value: 0.0

382843
type: LocalParameter
units: 304591
value: 13.5135135135135

382841
type: LocalParameter
units: 304591
value: 0.0

324273
type: SpeciesReference
stoichiometry: 1.0
species: 377787

378897
type: Reaction
reactant: 310913
product: 310949
name: cytochromecoxidase,mitochondrialComplexIV
reactant: 310925
product: 310973
product: 310985
reversible: false
reactant: 310937
fast: false
notes: GENE_ASSOCIATION: (1351.1) and (1329.1) and (1347.1) and (1327.1) and (9167.1) and (341947.1) and (4512.1) and (1350.1) and (1349.1) and (1339.1) and (4513.1) and (9377.1) and (1345.1) and (125965.1) and (4514.1) and (170712.1) and (1346.1) and (1340.1) and (1337.1) and (84701.1) SUBSYSTEM: Oxidative Phosphorylation
product: 310961
kinetic law: 310997

310913
type: SpeciesReference
stoichiometry: 4.0
species: 377920

310949
type: SpeciesReference
stoichiometry: 4.0
species: 377917

310925
type: SpeciesReference
stoichiometry: 7.92
species: 378083

310973
type: SpeciesReference
stoichiometry: 4.0
species: 378077

310985
type: SpeciesReference
stoichiometry: 0.02
species: 378284

310937
type: SpeciesReference
stoichiometry: 1.0
species: 378272

310961
type: SpeciesReference
stoichiometry: 1.96
species: 378065

381074
type: LocalParameter
units: 304591
value: 0.0

381071
type: LocalParameter
units: 304591
value: 0.0

381068
type: LocalParameter
units: 304591
value: 1000.0

381065
type: LocalParameter
units: 304591
value: 0.0

378738
type: Reaction
kinetic law: 307787
product: 307775
reactant: 307763
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: acetyl-CoAtransport,nuclear

380544
type: LocalParameter
units: 304591
value: 0.0

380541
type: LocalParameter
units: 304591
value: 0.0

380538
type: LocalParameter
units: 304591
value: 1000.0

380535
type: LocalParameter
units: 304591
value: -1000.0

307775
type: SpeciesReference
stoichiometry: 1.0
species: 377676

307763
type: SpeciesReference
stoichiometry: 1.0
species: 377673

379485
type: Reaction
product: 322323
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
reactant: 322262
product: 322298
reactant: 322286
name: retinaldehydrogenase(NADPH)
fast: false
reactant: 322274
kinetic law: 322335
product: 322310
reversible: true

322323
type: SpeciesReference
stoichiometry: 1.0
species: 378236

322262
type: SpeciesReference
stoichiometry: 1.0
species: 378059

322298
type: SpeciesReference
stoichiometry: 1.0
species: 377574

322286
type: SpeciesReference
stoichiometry: 1.0
species: 378422

322274
type: SpeciesReference
stoichiometry: 1.0
species: 378227

382616
type: LocalParameter
units: 304591
value: 0.0

382614
type: LocalParameter
units: 304591
value: 0.0

382612
type: LocalParameter
units: 304591
value: 1000.0

382610
type: LocalParameter
units: 304591
value: -1000.0

322310
type: SpeciesReference
stoichiometry: 2.0
species: 378077

379641
type: Reaction
kinetic law: 324743
reactant: 324731
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382954
type: LocalParameter
units: 304591
value: 0.0

382953
type: LocalParameter
units: 304591
value: 0.0

382952
type: LocalParameter
units: 304591
value: 13.5135135135135

382951
type: LocalParameter
units: 304591
value: 0.0

324731
type: SpeciesReference
stoichiometry: 1.0
species: 378104

378825
type: Reaction
kinetic law: 309320
product: 309307
product: 309295
reactant: 309283
notes: GENE_ASSOCIATION: (112.1) or (112.2) SUBSYSTEM: Nucleotides
fast: false
reversible: false
name: adenylatecyclase

380834
type: LocalParameter
units: 304591
value: 0.0

380831
type: LocalParameter
units: 304591
value: 0.0

380828
type: LocalParameter
units: 304591
value: 1000.0

380825
type: LocalParameter
units: 304591
value: 0.0

309307
type: SpeciesReference
stoichiometry: 1.0
species: 378359

309295
type: SpeciesReference
stoichiometry: 1.0
species: 377787

309283
type: SpeciesReference
stoichiometry: 1.0
species: 377769

378579
type: Reaction
kinetic law: 304711
product: 304699
product: 304687
reactant: 304675
notes: GENE_ASSOCIATION: (226.2) or (226.1) or (226.3) or (229.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
reversible: true
name: fructose-bisphosphatealdolase

379920
type: LocalParameter
units: 304591
value: 0.0

379917
type: LocalParameter
units: 304591
value: 0.0

379914
type: LocalParameter
units: 304591
value: 1000.0

379911
type: LocalParameter
units: 304591
value: -1000.0

304699
type: SpeciesReference
stoichiometry: 1.0
species: 377933

304687
type: SpeciesReference
stoichiometry: 1.0
species: 377871

304675
type: SpeciesReference
stoichiometry: 1.0
species: 377914

378768
type: Reaction
kinetic law: 308293
product: 308281
reactant: 308269
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: true
name: L-prolinetransport,mitochondrial

380644
type: LocalParameter
units: 304591
value: 0.0

380641
type: LocalParameter
units: 304591
value: 0.0

380638
type: LocalParameter
units: 304591
value: 1000.0

380635
type: LocalParameter
units: 304591
value: -1000.0

308281
type: SpeciesReference
stoichiometry: 1.0
species: 378383

308269
type: SpeciesReference
stoichiometry: 1.0
species: 378377

378407
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Pyruvate

378804
type: Reaction
product: 308982
reversible: false
fast: false
kinetic law: 308994
product: 308970
reactant: 308946
notes: GENE_ASSOCIATION: (6652.1) SUBSYSTEM: Fructose and Mannose Metabolism
reactant: 308934
name: D-sorbitoldehydrogenase(D-fructoseproducing)
product: 308958

308982
type: SpeciesReference
stoichiometry: 1.0
species: 378218

380764
type: LocalParameter
units: 304591
value: 0.0

380761
type: LocalParameter
units: 304591
value: 0.0

380758
type: LocalParameter
units: 304591
value: 1000.0

380755
type: LocalParameter
units: 304591
value: 0.0

308970
type: SpeciesReference
stoichiometry: 1.0
species: 378077

308946
type: SpeciesReference
stoichiometry: 1.0
species: 378446

308934
type: SpeciesReference
stoichiometry: 1.0
species: 378212

308958
type: SpeciesReference
stoichiometry: 1.0
species: 377927

379062
type: Reaction
fast: false
reversible: false
product: 314545
notes: GENE_ASSOCIATION: (1594.1) SUBSYSTEM: Vitamin D
kinetic law: 314569
reactant: 314496
product: 314533
product: 314557
reactant: 314509
reactant: 314484
name: 1-alpha-VitaminD-25-hydroxylase(D3)
reactant: 314521

314545
type: SpeciesReference
stoichiometry: 1.0
species: 378065

381615
type: LocalParameter
units: 304591
value: 0.0

381613
type: LocalParameter
units: 304591
value: 0.0

381611
type: LocalParameter
units: 304591
value: 1000.0

381609
type: LocalParameter
units: 304591
value: 0.0

314496
type: SpeciesReference
stoichiometry: 1.0
species: 378083

314533
type: SpeciesReference
stoichiometry: 1.0
species: 377583

314557
type: SpeciesReference
stoichiometry: 1.0
species: 378230

314509
type: SpeciesReference
stoichiometry: 1.0
species: 378239

314484
type: SpeciesReference
stoichiometry: 1.0
species: 377601

314521
type: SpeciesReference
stoichiometry: 1.0
species: 378272

379116
type: Reaction
name: D-alanine/glycinereversibleexchange
reactant: 315523
fast: false
reactant: 315535
reversible: true
kinetic law: 315572
product: 315559
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
product: 315547

315523
type: SpeciesReference
stoichiometry: 1.0
species: 377721

315535
type: SpeciesReference
stoichiometry: 1.0
species: 377993

381741
type: LocalParameter
units: 304591
value: 0.0

381739
type: LocalParameter
units: 304591
value: 0.0

381737
type: LocalParameter
units: 304591
value: 1000.0

381735
type: LocalParameter
units: 304591
value: -1000.0

315559
type: SpeciesReference
stoichiometry: 1.0
species: 377996

315547
type: SpeciesReference
stoichiometry: 1.0
species: 377718

379224
type: Reaction
reactant: 317636
notes: GENE_ASSOCIATION: (9058.1) SUBSYSTEM: Transport, Extracellular
reversible: true
kinetic law: 317673
product: 317649
reactant: 317624
name: succinatetransportviasodiumsymport
product: 317661
fast: false

317636
type: SpeciesReference
stoichiometry: 1.0
species: 378488

381992
type: LocalParameter
units: 304591
value: 0.0

381990
type: LocalParameter
units: 304591
value: 0.0

381988
type: LocalParameter
units: 304591
value: 1000.0

381986
type: LocalParameter
units: 304591
value: -1000.0

317649
type: SpeciesReference
stoichiometry: 2.0
species: 378206

317624
type: SpeciesReference
stoichiometry: 2.0
species: 378209

317661
type: SpeciesReference
stoichiometry: 1.0
species: 378485

378885
type: Reaction
kinetic law: 310671
product: 310659
product: 310646
reactant: 310634
notes: GENE_ASSOCIATION: (847.1) SUBSYSTEM: ROS Detoxification
fast: false
reversible: false
name: catalase

381034
type: LocalParameter
units: 304591
value: 0.0

381031
type: LocalParameter
units: 304591
value: 0.0

381028
type: LocalParameter
units: 304591
value: 1000.0

381025
type: LocalParameter
units: 304591
value: 0.0

310659
type: SpeciesReference
stoichiometry: 1.0
species: 378272

310646
type: SpeciesReference
stoichiometry: 2.0
species: 378065

310634
type: SpeciesReference
stoichiometry: 2.0
species: 378053

379347
type: Reaction
kinetic law: 319797
product: 319785
reactant: 319773
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: Htransporter,peroxisome

382279
type: LocalParameter
units: 304591
value: 0.0

382277
type: LocalParameter
units: 304591
value: 0.0

382275
type: LocalParameter
units: 304591
value: 1000.0

382273
type: LocalParameter
units: 304591
value: -1000.0

319785
type: SpeciesReference
stoichiometry: 1.0
species: 378089

319773
type: SpeciesReference
stoichiometry: 1.0
species: 378077

379302
type: Reaction
kinetic law: 319037
product: 319025
reactant: 319013
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: false
name: glucuronateendoplasmicreticulartransport

382174
type: LocalParameter
units: 304591
value: 0.0

382172
type: LocalParameter
units: 304591
value: 0.0

382170
type: LocalParameter
units: 304591
value: 1000.0

382168
type: LocalParameter
units: 304591
value: 0.0

319025
type: SpeciesReference
stoichiometry: 1.0
species: 377963

319013
type: SpeciesReference
stoichiometry: 1.0
species: 377960

379185
type: Reaction
kinetic law: 316875
product: 316863
reactant: 316851
notes: GENE_ASSOCIATION: (6526.1) or (6523.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: sodiumtransport(uniport)

381901
type: LocalParameter
units: 304591
value: 0.0

381899
type: LocalParameter
units: 304591
value: 0.0

381897
type: LocalParameter
units: 304591
value: 1000.0

381895
type: LocalParameter
units: 304591
value: 0.0

316863
type: SpeciesReference
stoichiometry: 1.0
species: 378206

316851
type: SpeciesReference
stoichiometry: 1.0
species: 378209

378789
type: Reaction
product: 308655
reactant: 308631
fast: false
reactant: 308619
notes: GENE_ASSOCIATION: (9123.1) SUBSYSTEM: Transport, Extracellular
reversible: true
product: 308643
name: pyruvatereversibletransportviaprotonsymport
kinetic law: 308667

308655
type: SpeciesReference
stoichiometry: 1.0
species: 378404

308631
type: SpeciesReference
stoichiometry: 1.0
species: 378407

308619
type: SpeciesReference
stoichiometry: 1.0
species: 378080

308643
type: SpeciesReference
stoichiometry: 1.0
species: 378077

380714
type: LocalParameter
units: 304591
value: 0.0

380711
type: LocalParameter
units: 304591
value: 0.0

380708
type: LocalParameter
units: 304591
value: 0.0

380705
type: LocalParameter
units: 304591
value: -1000.0

379864
type: Reaction
kinetic law: 326551
reactant: 326539
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Acetateexchange

383254
type: LocalParameter
units: 304591
value: 0.0

383253
type: LocalParameter
units: 304591
value: 0.0

383252
type: LocalParameter
units: 304591
value: 0.0

383251
type: LocalParameter
units: 304591
value: -1000.0

326539
type: SpeciesReference
stoichiometry: 1.0
species: 377655

378741
type: Reaction
kinetic law: 307824
product: 307812
reactant: 307800
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: coenzymeAtransport,nuclear

380554
type: LocalParameter
units: 304591
value: 0.0

380551
type: LocalParameter
units: 304591
value: 0.0

380548
type: LocalParameter
units: 304591
value: 1000.0

380545
type: LocalParameter
units: 304591
value: -1000.0

307812
type: SpeciesReference
stoichiometry: 1.0
species: 377832

307800
type: SpeciesReference
stoichiometry: 1.0
species: 377826

378756
type: Reaction
kinetic law: 308065
product: 308053
reactant: 308041
reactant: 308029
notes: GENE_ASSOCIATION: (205.1) or (205.3) or (205.2) SUBSYSTEM: Nucleotides
fast: false
reversible: true
name: adenylatekinase,mitochondrial

380604
type: LocalParameter
units: 304591
value: 0.0

380601
type: LocalParameter
units: 304591
value: 0.0

380598
type: LocalParameter
units: 304591
value: 1000.0

380595
type: LocalParameter
units: 304591
value: -1000.0

308053
type: SpeciesReference
stoichiometry: 2.0
species: 377703

308041
type: SpeciesReference
stoichiometry: 1.0
species: 377772

308029
type: SpeciesReference
stoichiometry: 1.0
species: 377736

379218
type: Reaction
name: choline,sodiumcotransport
reversible: true
reactant: 317501
reactant: 317513
kinetic law: 317551
product: 317525
product: 317538
fast: false
notes: GENE_ASSOCIATION: (60482.1) SUBSYSTEM: Transport, Extracellular

317501
type: SpeciesReference
stoichiometry: 1.0
species: 377796

317513
type: SpeciesReference
stoichiometry: 1.0
species: 378209

381978
type: LocalParameter
units: 304591
value: 0.0

381976
type: LocalParameter
units: 304591
value: 0.0

381974
type: LocalParameter
units: 304591
value: 1000.0

381972
type: LocalParameter
units: 304591
value: -1000.0

317525
type: SpeciesReference
stoichiometry: 1.0
species: 377793

317538
type: SpeciesReference
stoichiometry: 1.0
species: 378206

379041
type: Reaction
product: 314043
reactant: 314019
reactant: 314031
reversible: false
kinetic law: 314067
fast: false
product: 314055
name: phosphatidylinositol-4-phosphate4-phosphatase
notes: GENE_ASSOCIATION: SUBSYSTEM: Inositol Phosphate Metabolism

314043
type: SpeciesReference
stoichiometry: 1.0
species: 378323

314019
type: SpeciesReference
stoichiometry: 1.0
species: 378059

314031
type: SpeciesReference
stoichiometry: 1.0
species: 378314

381554
type: LocalParameter
units: 304591
value: 0.0

381551
type: LocalParameter
units: 304591
value: 0.0

381548
type: LocalParameter
units: 304591
value: 1000.0

381545
type: LocalParameter
units: 304591
value: 0.0

314055
type: SpeciesReference
stoichiometry: 1.0
species: 378338

378945
type: Reaction
notes: GENE_ASSOCIATION: (3795.1) or (3795.2) SUBSYSTEM: Fructose and Mannose Metabolism
fast: false
reactant: 312062
reactant: 312050
product: 312098
product: 312086
name: ketohexokinase
product: 312074
reversible: false
kinetic law: 312110

312062
type: SpeciesReference
stoichiometry: 1.0
species: 377927

312050
type: SpeciesReference
stoichiometry: 1.0
species: 377769

312098
type: SpeciesReference
stoichiometry: 1.0
species: 378077

312086
type: SpeciesReference
stoichiometry: 1.0
species: 377904

312074
type: SpeciesReference
stoichiometry: 1.0
species: 377700

381234
type: LocalParameter
units: 304591
value: 0.0

381231
type: LocalParameter
units: 304591
value: 0.0

381228
type: LocalParameter
units: 304591
value: 1000.0

381225
type: LocalParameter
units: 304591
value: 0.0

379056
type: Reaction
product: 314387
reactant: 314351
name: sphingosinekinase2
reactant: 314363
notes: GENE_ASSOCIATION: (56848.1) SUBSYSTEM: Sphingolipid Metabolism
product: 314399
product: 314375
kinetic law: 314411
reversible: false
fast: false

314387
type: SpeciesReference
stoichiometry: 1.0
species: 378077

314351
type: SpeciesReference
stoichiometry: 1.0
species: 377769

314363
type: SpeciesReference
stoichiometry: 1.0
species: 378473

314399
type: SpeciesReference
stoichiometry: 1.0
species: 378479

314375
type: SpeciesReference
stoichiometry: 1.0
species: 377700

381600
type: LocalParameter
units: 304591
value: 0.0

381597
type: LocalParameter
units: 304591
value: 0.0

381594
type: LocalParameter
units: 304591
value: 1000.0

381592
type: LocalParameter
units: 304591
value: 0.0

378699
type: Reaction
name: Diphosphoglyceratephosphatase
fast: false
product: 307075
reversible: false
reactant: 307051
kinetic law: 307099
reactant: 307063
notes: GENE_ASSOCIATION: (5223.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
product: 307087

307075
type: SpeciesReference
stoichiometry: 1.0
species: 377616

307051
type: SpeciesReference
stoichiometry: 1.0
species: 377592

380414
type: LocalParameter
units: 304591
value: 0.0

380411
type: LocalParameter
units: 304591
value: 0.0

380408
type: LocalParameter
units: 304591
value: 1000.0

380405
type: LocalParameter
units: 304591
value: 0.0

307063
type: SpeciesReference
stoichiometry: 1.0
species: 378059

307087
type: SpeciesReference
stoichiometry: 1.0
species: 378338

378987
type: Reaction
kinetic law: 312933
notes: GENE_ASSOCIATION: SUBSYSTEM: Ascorbate and Aldarate Metabolism
product: 312909
reactant: 312897
product: 312921
reversible: false
fast: false
reactant: 312885

381374
type: LocalParameter
units: 304591
value: 0.0

381371
type: LocalParameter
units: 304591
value: 0.0

381368
type: LocalParameter
units: 304591
value: 1000.0

381365
type: LocalParameter
units: 304591
value: 0.0

312909
type: SpeciesReference
stoichiometry: 1.0
species: 377754

312897
type: SpeciesReference
stoichiometry: 2.0
species: 378017

312921
type: SpeciesReference
stoichiometry: 1.0
species: 378011

312885
type: SpeciesReference
stoichiometry: 1.0
species: 377874

379287
type: Reaction
notes: GENE_ASSOCIATION: (6559.1) SUBSYSTEM: Transport, Extracellular
reversible: false
product: 318724
name: Na+-Cl-cotransport
reactant: 318712
product: 318736
kinetic law: 318749
reactant: 318699
fast: false

318724
type: SpeciesReference
stoichiometry: 1.0
species: 377811

318712
type: SpeciesReference
stoichiometry: 1.0
species: 378209

318736
type: SpeciesReference
stoichiometry: 1.0
species: 378206

382139
type: LocalParameter
units: 304591
value: 0.0

382137
type: LocalParameter
units: 304591
value: 0.0

382135
type: LocalParameter
units: 304591
value: 1000.0

382133
type: LocalParameter
units: 304591
value: 0.0

318699
type: SpeciesReference
stoichiometry: 1.0
species: 377814

379879
type: Reaction
kinetic law: 326672
reactant: 326659
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: D-Riboseexchange

383274
type: LocalParameter
units: 304591
value: 0.0

383273
type: LocalParameter
units: 304591
value: 0.0

383272
type: LocalParameter
units: 304591
value: 13.5135135135135

383271
type: LocalParameter
units: 304591
value: -1000.0

326659
type: SpeciesReference
stoichiometry: 1.0
species: 378437

379533
type: Reaction
kinetic law: 323082
product: 323070
reactant: 323058
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: ethanolreversibleperoxisomaltransport

382728
type: LocalParameter
units: 304591
value: 0.0

382726
type: LocalParameter
units: 304591
value: 0.0

382724
type: LocalParameter
units: 304591
value: 1000.0

382722
type: LocalParameter
units: 304591
value: -1000.0

323070
type: SpeciesReference
stoichiometry: 1.0
species: 377901

323058
type: SpeciesReference
stoichiometry: 1.0
species: 377895

379713
type: Reaction
kinetic law: 325323
reactant: 325311
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
name: 4-oxo-retonoicaciddemand

383050
type: LocalParameter
units: 304591
value: 0.0

383049
type: LocalParameter
units: 304591
value: 0.0

383048
type: LocalParameter
units: 304591
value: 13.5135135135135

383047
type: LocalParameter
units: 304591
value: 0.0

325311
type: SpeciesReference
stoichiometry: 1.0
species: 378296

378368
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: pristanic acid

378678
type: Reaction
kinetic law: 306687
product: 306675
reactant: 306663
notes: GENE_ASSOCIATION: (50.1) SUBSYSTEM: Citric Acid Cycle
fast: false
reversible: true
name: Aconitatehydratase

380344
type: LocalParameter
units: 304591
value: 0.0

380341
type: LocalParameter
units: 304591
value: 0.0

380338
type: LocalParameter
units: 304591
value: 1000.0

380335
type: LocalParameter
units: 304591
value: -1000.0

306675
type: SpeciesReference
stoichiometry: 1.0
species: 378119

306663
type: SpeciesReference
stoichiometry: 1.0
species: 377808

378684
type: Reaction
notes: GENE_ASSOCIATION: (4190.1) SUBSYSTEM: Citric Acid Cycle
kinetic law: 306843
name: malatedehydrogenase
product: 306819
reactant: 306795
product: 306831
product: 306807
reversible: true
reactant: 306783
fast: false

380364
type: LocalParameter
units: 304591
value: 0.0

380361
type: LocalParameter
units: 304591
value: 0.0

380358
type: LocalParameter
units: 304591
value: 1000.0

380355
type: LocalParameter
units: 304591
value: -1000.0

306819
type: SpeciesReference
stoichiometry: 1.0
species: 378218

306795
type: SpeciesReference
stoichiometry: 1.0
species: 378212

306831
type: SpeciesReference
stoichiometry: 1.0
species: 378290

306807
type: SpeciesReference
stoichiometry: 1.0
species: 378077

306783
type: SpeciesReference
stoichiometry: 1.0
species: 378182

379272
type: Reaction
product: 318446
reversible: true
notes: GENE_ASSOCIATION: (11001.1) SUBSYSTEM: Transport, Extracellular
reactant: 318434
fast: false
name: fattyacidelectroneutraltransport
reactant: 318422
kinetic law: 318470
product: 318458

318446
type: SpeciesReference
stoichiometry: 1.0
species: 378209

318434
type: SpeciesReference
stoichiometry: 1.0
species: 378260

318422
type: SpeciesReference
stoichiometry: 1.0
species: 378206

382104
type: LocalParameter
units: 304591
value: 0.0

382102
type: LocalParameter
units: 304591
value: 0.0

382100
type: LocalParameter
units: 304591
value: 1000.0

382098
type: LocalParameter
units: 304591
value: -1000.0

318458
type: SpeciesReference
stoichiometry: 1.0
species: 378263

379818
type: Reaction
kinetic law: 326166
reactant: 326154
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Threonineexchange

383190
type: LocalParameter
units: 304591
value: 0.0

383189
type: LocalParameter
units: 304591
value: 0.0

383188
type: LocalParameter
units: 304591
value: 0.0

383187
type: LocalParameter
units: 304591
value: -1000.0

326154
type: SpeciesReference
stoichiometry: 1.0
species: 378503

379803
type: Reaction
kinetic law: 326045
reactant: 326033
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Inosineexchange

383170
type: LocalParameter
units: 304591
value: 0.0

383169
type: LocalParameter
units: 304591
value: 0.0

383168
type: LocalParameter
units: 304591
value: 13.5135135135135

383167
type: LocalParameter
units: 304591
value: -1000.0

326033
type: SpeciesReference
stoichiometry: 1.0
species: 378137

379833
type: Reaction
kinetic law: 326286
reactant: 326274
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Leucineexchange

383210
type: LocalParameter
units: 304591
value: 0.0

383209
type: LocalParameter
units: 304591
value: 0.0

383208
type: LocalParameter
units: 304591
value: 0.0

383207
type: LocalParameter
units: 304591
value: -1000.0

326274
type: SpeciesReference
stoichiometry: 1.0
species: 378161

379653
type: Reaction
kinetic law: 324839
reactant: 324827
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382970
type: LocalParameter
units: 304591
value: 0.0

382969
type: LocalParameter
units: 304591
value: 0.0

382968
type: LocalParameter
units: 304591
value: 13.5135135135135

382967
type: LocalParameter
units: 304591
value: 0.0

324827
type: SpeciesReference
stoichiometry: 1.0
species: 377850

378771
type: Reaction
reversible: true
notes: GENE_ASSOCIATION: (79751.1) SUBSYSTEM: Transport, Mitochondrial
product: 308341
product: 308329
reactant: 308317
kinetic law: 308353
fast: false
name: L-glutamatereversibletransportviaprotonsymport,mitochondrial
reactant: 308305

308341
type: SpeciesReference
stoichiometry: 1.0
species: 378083

308329
type: SpeciesReference
stoichiometry: 1.0
species: 377984

308317
type: SpeciesReference
stoichiometry: 1.0
species: 378077

380654
type: LocalParameter
units: 304591
value: 0.0

380651
type: LocalParameter
units: 304591
value: 0.0

380648
type: LocalParameter
units: 304591
value: 0.0

380645
type: LocalParameter
units: 304591
value: -1000.0

308305
type: SpeciesReference
stoichiometry: 1.0
species: 377978

378606
type: Reaction
kinetic law: 305218
product: 305206
reactant: 305194
notes: GENE_ASSOCIATION: (22934.1) SUBSYSTEM: Pentose Phosphate Pathway
fast: false
reversible: true
name: ribose-5-phosphateisomerase

380010
type: LocalParameter
units: 304591
value: 0.0

380007
type: LocalParameter
units: 304591
value: 0.0

380004
type: LocalParameter
units: 304591
value: 1000.0

380001
type: LocalParameter
units: 304591
value: 0.0

305206
type: SpeciesReference
stoichiometry: 1.0
species: 378440

305194
type: SpeciesReference
stoichiometry: 1.0
species: 378419

379794
type: Reaction
kinetic law: 325973
reactant: 325961
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Deoxyadenosineexchange

383158
type: LocalParameter
units: 304591
value: 0.0

383157
type: LocalParameter
units: 304591
value: 0.0

383156
type: LocalParameter
units: 304591
value: 13.5135135135135

383155
type: LocalParameter
units: 304591
value: 0.0

325961
type: SpeciesReference
stoichiometry: 1.0
species: 377859

378837
type: Reaction
kinetic law: 309560
product: 309548
product: 309536
reactant: 309524
notes: GENE_ASSOCIATION: (226.2) or (226.1) or (226.3) or (229.1) SUBSYSTEM: Fructose and Mannose Metabolism
fast: false
reversible: true
name: D-Fructose1-phosphateD-glyceraldehyde-3-phosphate-lyase

380874
type: LocalParameter
units: 304591
value: 0.0

380871
type: LocalParameter
units: 304591
value: 0.0

380868
type: LocalParameter
units: 304591
value: 1000.0

380865
type: LocalParameter
units: 304591
value: -1000.0

309548
type: SpeciesReference
stoichiometry: 1.0
species: 378002

309536
type: SpeciesReference
stoichiometry: 1.0
species: 377871

309524
type: SpeciesReference
stoichiometry: 1.0
species: 377904

379605
type: Reaction
kinetic law: 324454
reactant: 324442
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382896
type: LocalParameter
units: 304591
value: 0.0

382894
type: LocalParameter
units: 304591
value: 0.0

382892
type: LocalParameter
units: 304591
value: 13.5135135135135

382890
type: LocalParameter
units: 304591
value: 0.0

324442
type: SpeciesReference
stoichiometry: 1.0
species: 377790

379134
type: Reaction
fast: false
product: 315922
kinetic law: 315934
reversible: true
product: 315910
reactant: 315898
reactant: 315886
notes: GENE_ASSOCIATION: SUBSYSTEM: Cysteine Metabolism
name: Glutathione:cystineoxidoreductase

315922
type: SpeciesReference
stoichiometry: 1.0
species: 378011

381782
type: LocalParameter
units: 304591
value: 0.0

381781
type: LocalParameter
units: 304591
value: 0.0

381779
type: LocalParameter
units: 304591
value: 1000.0

381777
type: LocalParameter
units: 304591
value: -1000.0

315910
type: SpeciesReference
stoichiometry: 2.0
species: 377850

315898
type: SpeciesReference
stoichiometry: 2.0
species: 378017

315886
type: SpeciesReference
stoichiometry: 1.0
species: 377634

379149
type: Reaction
product: 316296
name: L-cystine/glycineexchanger(cystinein)
reactant: 316284
notes: GENE_ASSOCIATION: (6519.1 and 11136.1) SUBSYSTEM: Transport, Extracellular
kinetic law: 316321
product: 316308
reversible: false
reactant: 316272
fast: false

316296
type: SpeciesReference
stoichiometry: 1.0
species: 377634

316284
type: SpeciesReference
stoichiometry: 1.0
species: 378455

381817
type: LocalParameter
units: 304591
value: 0.0

381815
type: LocalParameter
units: 304591
value: 0.0

381813
type: LocalParameter
units: 304591
value: 1000.0

381811
type: LocalParameter
units: 304591
value: 0.0

316308
type: SpeciesReference
stoichiometry: 1.0
species: 378458

316272
type: SpeciesReference
stoichiometry: 1.0
species: 377637

379897
type: Reaction
kinetic law: 326817
reactant: 326805
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: H2Oexchange

383298
type: LocalParameter
units: 304591
value: 0.0

383297
type: LocalParameter
units: 304591
value: 0.0

383296
type: LocalParameter
units: 304591
value: 0.0

383295
type: LocalParameter
units: 304591
value: -1000.0

326805
type: SpeciesReference
stoichiometry: 1.0
species: 378062

378900
type: Reaction
kinetic law: 311033
product: 311021
reactant: 311009
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: true
name: acetaldehydemitochondrialdiffusion

381084
type: LocalParameter
units: 304591
value: 0.0

381081
type: LocalParameter
units: 304591
value: 0.0

381078
type: LocalParameter
units: 304591
value: 1000.0

381075
type: LocalParameter
units: 304591
value: -1000.0

311021
type: SpeciesReference
stoichiometry: 1.0
species: 377661

311009
type: SpeciesReference
stoichiometry: 1.0
species: 377667

379005
type: Reaction
kinetic law: 313296
product: 313283
reactant: 313271
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: deoyguanosinetransportviadiffusion

381434
type: LocalParameter
units: 304591
value: 0.0

381431
type: LocalParameter
units: 304591
value: 0.0

381428
type: LocalParameter
units: 304591
value: 1000.0

381425
type: LocalParameter
units: 304591
value: -1000.0

313283
type: SpeciesReference
stoichiometry: 1.0
species: 377865

313271
type: SpeciesReference
stoichiometry: 1.0
species: 377868

379128
type: Reaction
reactant: 315777
reactant: 315765
reversible: true
product: 315801
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
kinetic law: 315813
product: 315789
fast: false
name: L-cysteine/L-glutaminereversibleexchanger

315777
type: SpeciesReference
stoichiometry: 1.0
species: 377966

315765
type: SpeciesReference
stoichiometry: 1.0
species: 377853

315801
type: SpeciesReference
stoichiometry: 1.0
species: 377969

381769
type: LocalParameter
units: 304591
value: 0.0

381767
type: LocalParameter
units: 304591
value: 0.0

381765
type: LocalParameter
units: 304591
value: 1000.0

381763
type: LocalParameter
units: 304591
value: -1000.0

315789
type: SpeciesReference
stoichiometry: 1.0
species: 377850

379197
type: Reaction
reactant: 317068
reversible: true
product: 317092
reactant: 317080
name: bicarbonatetransport(Na/HCO31:2cotransport)
kinetic law: 317117
product: 317104
notes: GENE_ASSOCIATION: (8671.1) SUBSYSTEM: Transport, Extracellular
fast: false

317068
type: SpeciesReference
stoichiometry: 2.0
species: 378095

317092
type: SpeciesReference
stoichiometry: 2.0
species: 378092

317080
type: SpeciesReference
stoichiometry: 1.0
species: 378209

381929
type: LocalParameter
units: 304591
value: 0.0

381927
type: LocalParameter
units: 304591
value: 0.0

381925
type: LocalParameter
units: 304591
value: 1000.0

381923
type: LocalParameter
units: 304591
value: -1000.0

317104
type: SpeciesReference
stoichiometry: 1.0
species: 378206

379290
type: Reaction
reactant: 318775
reversible: true
reactant: 318762
name: K+-Cl-cotransport
notes: GENE_ASSOCIATION: (10723.1) SUBSYSTEM: Transport, Extracellular
product: 318788
kinetic law: 318814
fast: false
product: 318801

318775
type: SpeciesReference
stoichiometry: 1.0
species: 378143

318762
type: SpeciesReference
stoichiometry: 1.0
species: 377814

318788
type: SpeciesReference
stoichiometry: 1.0
species: 377811

382146
type: LocalParameter
units: 304591
value: 0.0

382144
type: LocalParameter
units: 304591
value: 0.0

382142
type: LocalParameter
units: 304591
value: 1000.0

382140
type: LocalParameter
units: 304591
value: -1000.0

318801
type: SpeciesReference
stoichiometry: 1.0
species: 378140

379876
type: Reaction
kinetic law: 326647
reactant: 326635
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: O2exchange

383270
type: LocalParameter
units: 304591
value: 0.0

383269
type: LocalParameter
units: 304591
value: 0.0

383268
type: LocalParameter
units: 304591
value: 13.5135135135135

383267
type: LocalParameter
units: 304591
value: -1000.0

326635
type: SpeciesReference
stoichiometry: 1.0
species: 378269

379882
type: Reaction
kinetic law: 326696
reactant: 326684
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: myo-Inositolexchange

383278
type: LocalParameter
units: 304591
value: 0.0

383277
type: LocalParameter
units: 304591
value: 0.0

383276
type: LocalParameter
units: 304591
value: 13.5135135135135

383275
type: LocalParameter
units: 304591
value: -1000.0

326684
type: SpeciesReference
stoichiometry: 1.0
species: 378131

379365
type: Reaction
reversible: false
reactant: 320075
reactant: 320099
notes: GENE_ASSOCIATION: (10327.2) or (8574.1) or (10327.1) or (231.1) SUBSYSTEM: Pyruvate Metabolism
kinetic law: 320135
fast: false
product: 320111
reactant: 320087
product: 320123
name: aldosereductase(acetol)

320075
type: SpeciesReference
stoichiometry: 1.0
species: 377679

320099
type: SpeciesReference
stoichiometry: 1.0
species: 378236

382321
type: LocalParameter
units: 304591
value: 0.0

382319
type: LocalParameter
units: 304591
value: 0.0

382317
type: LocalParameter
units: 304591
value: 1000.0

382315
type: LocalParameter
units: 304591
value: 0.0

320111
type: SpeciesReference
stoichiometry: 1.0
species: 377565

320087
type: SpeciesReference
stoichiometry: 1.0
species: 378077

320123
type: SpeciesReference
stoichiometry: 1.0
species: 378227

379320
type: Reaction
product: 319340
name: Na+/K+exchangingATPase
reactant: 319303
reactant: 319291
product: 319315
notes: GENE_ASSOCIATION: (483.1 and 476.1) or (481.1 and 476.1) SUBSYSTEM: Transport, Extracellular
reversible: false
product: 319328
kinetic law: 319376
product: 319364
reactant: 319279
reactant: 319267
product: 319352
fast: false

319340
type: SpeciesReference
stoichiometry: 2.0
species: 378140

319303
type: SpeciesReference
stoichiometry: 3.0
species: 378206

319291
type: SpeciesReference
stoichiometry: 2.0
species: 378143

319315
type: SpeciesReference
stoichiometry: 1.0
species: 377700

319328
type: SpeciesReference
stoichiometry: 1.0
species: 378077

382216
type: LocalParameter
units: 304591
value: 0.0

382214
type: LocalParameter
units: 304591
value: 0.0

382212
type: LocalParameter
units: 304591
value: 1000.0

382210
type: LocalParameter
units: 304591
value: 0.0

319364
type: SpeciesReference
stoichiometry: 1.0
species: 378338

319279
type: SpeciesReference
stoichiometry: 1.0
species: 378059

319267
type: SpeciesReference
stoichiometry: 1.0
species: 377769

319352
type: SpeciesReference
stoichiometry: 3.0
species: 378209

379074
type: Reaction
kinetic law: 314714
product: 314702
reactant: 314690
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: false

381643
type: LocalParameter
units: 304591
value: 0.0

381641
type: LocalParameter
units: 304591
value: 0.0

381639
type: LocalParameter
units: 304591
value: 1000.0

381637
type: LocalParameter
units: 304591
value: 0.0

314702
type: SpeciesReference
stoichiometry: 1.0
species: 377595

314690
type: SpeciesReference
stoichiometry: 1.0
species: 377601

379236
type: Reaction
reversible: true
reactant: 317855
notes: GENE_ASSOCIATION: (28234.1) SUBSYSTEM: Transport, Extracellular
reactant: 317843
name: bilirubinmonoglucuronidetransportviabicarbonatecountertransport
kinetic law: 317891
product: 317879
product: 317867
fast: false

317855
type: SpeciesReference
stoichiometry: 1.0
species: 378092

317843
type: SpeciesReference
stoichiometry: 1.0
species: 377778

382020
type: LocalParameter
units: 304591
value: 0.0

382018
type: LocalParameter
units: 304591
value: 0.0

382016
type: LocalParameter
units: 304591
value: 0.0

382014
type: LocalParameter
units: 304591
value: -1000.0

317879
type: SpeciesReference
stoichiometry: 1.0
species: 378095

317867
type: SpeciesReference
stoichiometry: 1.0
species: 377775

379551
type: Reaction
kinetic law: 323344
product: 323332
reactant: 323320
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: true

382770
type: LocalParameter
units: 304591
value: 0.0

382768
type: LocalParameter
units: 304591
value: 0.0

382766
type: LocalParameter
units: 304591
value: 1000.0

382764
type: LocalParameter
units: 304591
value: -1000.0

323332
type: SpeciesReference
stoichiometry: 1.0
species: 378284

323320
type: SpeciesReference
stoichiometry: 1.0
species: 378281

379359
type: Reaction
name: peroxisomalacyl-CoAthioesterase
reactant: 319929
notes: GENE_ASSOCIATION: (10965.1) SUBSYSTEM: Fatty Acid Metabolism
fast: false
product: 319954
reactant: 319942
reversible: false
product: 319978
product: 319966
kinetic law: 319990

319929
type: SpeciesReference
stoichiometry: 1.0
species: 378074

319954
type: SpeciesReference
stoichiometry: 1.0
species: 377835

319942
type: SpeciesReference
stoichiometry: 1.0
species: 378374

319978
type: SpeciesReference
stoichiometry: 1.0
species: 378368

319966
type: SpeciesReference
stoichiometry: 1.0
species: 378089

382307
type: LocalParameter
units: 304591
value: 0.0

382305
type: LocalParameter
units: 304591
value: 0.0

382303
type: LocalParameter
units: 304591
value: 1000.0

382301
type: LocalParameter
units: 304591
value: 0.0

379821
type: Reaction
kinetic law: 326190
reactant: 326178
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Pyruvateexchange

383194
type: LocalParameter
units: 304591
value: 0.0

383193
type: LocalParameter
units: 304591
value: 0.0

383192
type: LocalParameter
units: 304591
value: 13.5135135135135

383191
type: LocalParameter
units: 304591
value: -1000.0

326178
type: SpeciesReference
stoichiometry: 1.0
species: 378407

378957
type: Reaction
kinetic law: 312256
product: 312244
reactant: 312231
notes: GENE_ASSOCIATION: (2544.1) SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: phosphatetransport,endoplasmicreticulum

381274
type: LocalParameter
units: 304591
value: 0.0

381271
type: LocalParameter
units: 304591
value: 0.0

381268
type: LocalParameter
units: 304591
value: 1000.0

381265
type: LocalParameter
units: 304591
value: -1000.0

312244
type: SpeciesReference
stoichiometry: 1.0
species: 378338

312231
type: SpeciesReference
stoichiometry: 1.0
species: 378350

378696
type: Reaction
reversible: true
product: 307014
notes: GENE_ASSOCIATION: (5250.4) or (5250.1) or (5250.3) or (5250.2) SUBSYSTEM: Transport, Mitochondrial
product: 307027
fast: false
reactant: 307002
reactant: 306990
kinetic law: 307039
name: phosphatetransporter,mitochondrial

307014
type: SpeciesReference
stoichiometry: 1.0
species: 378083

307027
type: SpeciesReference
stoichiometry: 1.0
species: 378344

307002
type: SpeciesReference
stoichiometry: 1.0
species: 378338

306990
type: SpeciesReference
stoichiometry: 1.0
species: 378077

380404
type: LocalParameter
units: 304591
value: 0.0

380401
type: LocalParameter
units: 304591
value: 0.0

380398
type: LocalParameter
units: 304591
value: 1000.0

380395
type: LocalParameter
units: 304591
value: -1000.0

379800
type: Reaction
kinetic law: 326021
reactant: 326009
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Methionineexchange

383166
type: LocalParameter
units: 304591
value: 0.0

383165
type: LocalParameter
units: 304591
value: 0.0

383164
type: LocalParameter
units: 304591
value: 0.0

383163
type: LocalParameter
units: 304591
value: -1000.0

326009
type: SpeciesReference
stoichiometry: 1.0
species: 378191

379440
type: Reaction
kinetic law: 321547
product: 321535
reactant: 321523
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: 13-cis-retinoicacidtransport,nuclear

382496
type: LocalParameter
units: 304591
value: 0.0

382494
type: LocalParameter
units: 304591
value: 0.0

382492
type: LocalParameter
units: 304591
value: 1000.0

382490
type: LocalParameter
units: 304591
value: -1000.0

321535
type: SpeciesReference
stoichiometry: 1.0
species: 377577

321523
type: SpeciesReference
stoichiometry: 1.0
species: 377574

379743
type: Reaction
kinetic law: 325564
reactant: 325552
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: 25-HydroxyvitaminD3exchange

383090
type: LocalParameter
units: 304591
value: 0.0

383089
type: LocalParameter
units: 304591
value: 0.0

383088
type: LocalParameter
units: 304591
value: 13.5135135135135

383087
type: LocalParameter
units: 304591
value: -1000.0

325552
type: SpeciesReference
stoichiometry: 1.0
species: 377598

379479
type: Reaction
kinetic law: 322164
product: 322152
reactant: 322140
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: false
name: glycolatetransportintoperoxisome

382602
type: LocalParameter
units: 304591
value: 0.0

382600
type: LocalParameter
units: 304591
value: 0.0

382598
type: LocalParameter
units: 304591
value: 1000.0

382596
type: LocalParameter
units: 304591
value: 0.0

322152
type: SpeciesReference
stoichiometry: 1.0
species: 378008

322140
type: SpeciesReference
stoichiometry: 1.0
species: 378005

379815
type: Reaction
kinetic law: 326142
reactant: 326130
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Tyrosineexchange

383186
type: LocalParameter
units: 304591
value: 0.0

383185
type: LocalParameter
units: 304591
value: 0.0

383184
type: LocalParameter
units: 304591
value: 0.0

383183
type: LocalParameter
units: 304591
value: -1000.0

326130
type: SpeciesReference
stoichiometry: 1.0
species: 378518

378840
type: Reaction
reactant: 309584
kinetic law: 309620
fast: false
reversible: false
name: ADP/ATPtransporter,mitochondrial
product: 309596
product: 309608
reactant: 309572
notes: GENE_ASSOCIATION: (291.1) or (293.1) or (292.1) SUBSYSTEM: Transport, Mitochondrial

309584
type: SpeciesReference
stoichiometry: 1.0
species: 377772

380884
type: LocalParameter
units: 304591
value: 0.0

380881
type: LocalParameter
units: 304591
value: 0.0

380878
type: LocalParameter
units: 304591
value: 1000.0

380875
type: LocalParameter
units: 304591
value: 0.0

309596
type: SpeciesReference
stoichiometry: 1.0
species: 377703

309608
type: SpeciesReference
stoichiometry: 1.0
species: 377769

309572
type: SpeciesReference
stoichiometry: 1.0
species: 377700

379509
type: Reaction
reversible: false
product: 322636
name: phosphatidylinositol-4,5-bisphosphate5-phosphatase,nuclear
reactant: 322600
reactant: 322612
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Inositol Phosphate Metabolism
kinetic law: 322648
product: 322624

322636
type: SpeciesReference
stoichiometry: 1.0
species: 378347

322600
type: SpeciesReference
stoichiometry: 1.0
species: 378068

322612
type: SpeciesReference
stoichiometry: 1.0
species: 378311

382672
type: LocalParameter
units: 304591
value: 0.0

382670
type: LocalParameter
units: 304591
value: 0.0

382668
type: LocalParameter
units: 304591
value: 1000.0

382666
type: LocalParameter
units: 304591
value: 0.0

322624
type: SpeciesReference
stoichiometry: 1.0
species: 378317

379140
type: Reaction
product: 316043
fast: false
notes: GENE_ASSOCIATION: (6505.1) SUBSYSTEM: Transport, Extracellular
reactant: 315983
kinetic law: 316079
product: 316067
product: 316031
reactant: 315995
product: 316055
reversible: false
reactant: 316019
reactant: 316007
name: GlutamatetransportviaNa,HsymportandKantiport

316043
type: SpeciesReference
stoichiometry: 1.0
species: 378077

315983
type: SpeciesReference
stoichiometry: 1.0
species: 377981

381796
type: LocalParameter
units: 304591
value: 0.0

381794
type: LocalParameter
units: 304591
value: 0.0

381792
type: LocalParameter
units: 304591
value: 1000.0

381790
type: LocalParameter
units: 304591
value: 0.0

316067
type: SpeciesReference
stoichiometry: 3.0
species: 378206

316031
type: SpeciesReference
stoichiometry: 1.0
species: 377978

315995
type: SpeciesReference
stoichiometry: 1.0
species: 378080

316055
type: SpeciesReference
stoichiometry: 1.0
species: 378143

316019
type: SpeciesReference
stoichiometry: 3.0
species: 378209

316007
type: SpeciesReference
stoichiometry: 1.0
species: 378140

379602
type: Reaction
kinetic law: 324430
reactant: 324418
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382889
type: LocalParameter
units: 304591
value: 0.0

382887
type: LocalParameter
units: 304591
value: 0.0

382885
type: LocalParameter
units: 304591
value: 13.5135135135135

382883
type: LocalParameter
units: 304591
value: 0.0

324418
type: SpeciesReference
stoichiometry: 1.0
species: 378077

378783
type: Reaction
kinetic law: 308546
product: 308533
reactant: 308521
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: coenzymeAtransport,peroxisomal

380694
type: LocalParameter
units: 304591
value: 0.0

380691
type: LocalParameter
units: 304591
value: 0.0

380688
type: LocalParameter
units: 304591
value: 1000.0

380685
type: LocalParameter
units: 304591
value: -1000.0

308533
type: SpeciesReference
stoichiometry: 1.0
species: 377835

308521
type: SpeciesReference
stoichiometry: 1.0
species: 377826

379371
type: Reaction
name: alcoholdehydrogenase(D-1,2-propanediol)
product: 320268
reactant: 320232
product: 320256
reversible: false
product: 320244
kinetic law: 320280
notes: GENE_ASSOCIATION: (128.1) SUBSYSTEM: Pyruvate Metabolism
reactant: 320220
fast: false

320268
type: SpeciesReference
stoichiometry: 1.0
species: 378218

320232
type: SpeciesReference
stoichiometry: 1.0
species: 378212

320256
type: SpeciesReference
stoichiometry: 1.0
species: 378152

320244
type: SpeciesReference
stoichiometry: 1.0
species: 378077

382335
type: LocalParameter
units: 304591
value: 0.0

382333
type: LocalParameter
units: 304591
value: 0.0

382331
type: LocalParameter
units: 304591
value: 1000.0

382329
type: LocalParameter
units: 304591
value: 0.0

320220
type: SpeciesReference
stoichiometry: 1.0
species: 377562

379671
type: Reaction
kinetic law: 324983
reactant: 324971
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382994
type: LocalParameter
units: 304591
value: 0.0

382993
type: LocalParameter
units: 304591
value: 0.0

382992
type: LocalParameter
units: 304591
value: 13.5135135135135

382991
type: LocalParameter
units: 304591
value: 0.0

324971
type: SpeciesReference
stoichiometry: 1.0
species: 377802

379809
type: Reaction
kinetic law: 326093
reactant: 326081
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Ammoniaexchange

383178
type: LocalParameter
units: 304591
value: 0.0

383177
type: LocalParameter
units: 304591
value: 0.0

383176
type: LocalParameter
units: 304591
value: 13.5135135135135

383175
type: LocalParameter
units: 304591
value: -1000.0

326081
type: SpeciesReference
stoichiometry: 1.0
species: 378248

379617
type: Reaction
kinetic law: 324550
reactant: 324538
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382920
type: LocalParameter
units: 304591
value: 0.0

382919
type: LocalParameter
units: 304591
value: 0.0

382917
type: LocalParameter
units: 304591
value: 13.5135135135135

382916
type: LocalParameter
units: 304591
value: 0.0

324538
type: SpeciesReference
stoichiometry: 1.0
species: 378500

379830
type: Reaction
kinetic law: 326262
reactant: 326250
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Sodiumexchange

383206
type: LocalParameter
units: 304591
value: 0.0

383205
type: LocalParameter
units: 304591
value: 0.0

383204
type: LocalParameter
units: 304591
value: 0.0

383203
type: LocalParameter
units: 304591
value: -1000.0

326250
type: SpeciesReference
stoichiometry: 1.0
species: 378209

379665
type: Reaction
kinetic law: 324935
reactant: 324923
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382986
type: LocalParameter
units: 304591
value: 0.0

382985
type: LocalParameter
units: 304591
value: 0.0

382984
type: LocalParameter
units: 304591
value: 13.5135135135135

382983
type: LocalParameter
units: 304591
value: 0.0

324923
type: SpeciesReference
stoichiometry: 1.0
species: 377724

379650
type: Reaction
kinetic law: 324815
reactant: 324803
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false

382966
type: LocalParameter
units: 304591
value: 0.0

382965
type: LocalParameter
units: 304591
value: 0.0

382964
type: LocalParameter
units: 304591
value: 13.5135135135135

382963
type: LocalParameter
units: 304591
value: 0.0

324803
type: SpeciesReference
stoichiometry: 1.0
species: 377966

378762
type: Reaction
reversible: true
product: 308161
product: 308185
kinetic law: 308197
fast: false
name: glycinehydroxymethyltransferase,reversible
reactant: 308149
product: 308173
reactant: 308137
notes: GENE_ASSOCIATION: (6470.1) or (6470.2) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism

308161
type: SpeciesReference
stoichiometry: 1.0
species: 377993

308185
type: SpeciesReference
stoichiometry: 1.0
species: 378197

380624
type: LocalParameter
units: 304591
value: 0.0

380621
type: LocalParameter
units: 304591
value: 0.0

380618
type: LocalParameter
units: 304591
value: 1000.0

380615
type: LocalParameter
units: 304591
value: -1000.0

308149
type: SpeciesReference
stoichiometry: 1.0
species: 378497

308173
type: SpeciesReference
stoichiometry: 1.0
species: 378059

308137
type: SpeciesReference
stoichiometry: 1.0
species: 378455

379167
type: Reaction
kinetic law: 316610
product: 316598
reactant: 316586
notes: GENE_ASSOCIATION: (124935.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true

381859
type: LocalParameter
units: 304591
value: 0.0

381857
type: LocalParameter
units: 304591
value: 0.0

381855
type: LocalParameter
units: 304591
value: 1000.0

381853
type: LocalParameter
units: 304591
value: -1000.0

316598
type: SpeciesReference
stoichiometry: 1.0
species: 378536

316586
type: SpeciesReference
stoichiometry: 1.0
species: 378539

379758
type: Reaction
kinetic law: 325684
reactant: 325672
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: nC20:4exchange

383110
type: LocalParameter
units: 304591
value: 0.0

383109
type: LocalParameter
units: 304591
value: 0.0

383108
type: LocalParameter
units: 304591
value: 13.5135135135135

383107
type: LocalParameter
units: 304591
value: -1000.0

325672
type: SpeciesReference
stoichiometry: 1.0
species: 377742

378960
type: Reaction
fast: false
reactant: 312268
name: inorganicdiphosphatase,endoplasmicreticulum
reversible: false
kinetic law: 312316
product: 312292
product: 312304
notes: GENE_ASSOCIATION: (92579.1) SUBSYSTEM: Miscellaneous
reactant: 312280

312268
type: SpeciesReference
stoichiometry: 1.0
species: 378071

381284
type: LocalParameter
units: 304591
value: 0.0

381281
type: LocalParameter
units: 304591
value: 0.0

381278
type: LocalParameter
units: 304591
value: 1000.0

381275
type: LocalParameter
units: 304591
value: 0.0

312292
type: SpeciesReference
stoichiometry: 1.0
species: 378086

312304
type: SpeciesReference
stoichiometry: 2.0
species: 378350

312280
type: SpeciesReference
stoichiometry: 1.0
species: 378362

379446
type: Reaction
kinetic law: 321619
product: 321607
reactant: 321595
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: pristperoxisomaltransport

382510
type: LocalParameter
units: 304591
value: 0.0

382508
type: LocalParameter
units: 304591
value: 0.0

382506
type: LocalParameter
units: 304591
value: 1000.0

382504
type: LocalParameter
units: 304591
value: -1000.0

321607
type: SpeciesReference
stoichiometry: 1.0
species: 378365

321595
type: SpeciesReference
stoichiometry: 1.0
species: 378368

379146
type: Reaction
name: triokinase
kinetic law: 316260
reactant: 316212
product: 316248
reversible: false
product: 316224
reactant: 316199
product: 316236
notes: GENE_ASSOCIATION: SUBSYSTEM: Fructose and Mannose Metabolism
fast: false

381810
type: LocalParameter
units: 304591
value: 0.0

381808
type: LocalParameter
units: 304591
value: 0.0

381806
type: LocalParameter
units: 304591
value: 1000.0

381804
type: LocalParameter
units: 304591
value: 0.0

316212
type: SpeciesReference
stoichiometry: 1.0
species: 378002

316248
type: SpeciesReference
stoichiometry: 1.0
species: 378077

316224
type: SpeciesReference
stoichiometry: 1.0
species: 377700

316199
type: SpeciesReference
stoichiometry: 1.0
species: 377769

316236
type: SpeciesReference
stoichiometry: 1.0
species: 377933

379894
type: Reaction
kinetic law: 326793
reactant: 326781
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Phosphateexchange

383294
type: LocalParameter
units: 304591
value: 0.0

383293
type: LocalParameter
units: 304591
value: 0.0

383292
type: LocalParameter
units: 304591
value: 0.0

383291
type: LocalParameter
units: 304591
value: -1000.0

326781
type: SpeciesReference
stoichiometry: 1.0
species: 378341

378906
type: Reaction
kinetic law: 311142
product: 311130
reactant: 311118
reactant: 311106
notes: GENE_ASSOCIATION: SUBSYSTEM: Miscellaneous
fast: false
reversible: true
name: carboxylicaciddissociation

381104
type: LocalParameter
units: 304591
value: 0.0

381101
type: LocalParameter
units: 304591
value: 0.0

381098
type: LocalParameter
units: 304591
value: 1000.0

381095
type: LocalParameter
units: 304591
value: -1000.0

311130
type: SpeciesReference
stoichiometry: 1.0
species: 378044

311118
type: SpeciesReference
stoichiometry: 1.0
species: 378092

311106
type: SpeciesReference
stoichiometry: 1.0
species: 378077

378912
type: Reaction
name: methenyltetrahydrofolatecyclohydrolase
fast: false
reactant: 311227
reactant: 311215
kinetic law: 311263
reversible: true
notes: GENE_ASSOCIATION: (4522.1) or (285216.1) or (80068.1) SUBSYSTEM: Folate Metabolism
product: 311239
product: 311251

311227
type: SpeciesReference
stoichiometry: 1.0
species: 378194

311215
type: SpeciesReference
stoichiometry: 1.0
species: 378059

381124
type: LocalParameter
units: 304591
value: 0.0

381121
type: LocalParameter
units: 304591
value: 0.0

381118
type: LocalParameter
units: 304591
value: 1000.0

381115
type: LocalParameter
units: 304591
value: 0.0

311239
type: SpeciesReference
stoichiometry: 1.0
species: 377559

311251
type: SpeciesReference
stoichiometry: 1.0
species: 378077

379377
type: Reaction
product: 320413
name: alcoholdehydrogenase(L-lactaldehyde)
reactant: 320365
kinetic law: 320425
product: 320401
fast: false
product: 320389
notes: GENE_ASSOCIATION: (128.1) SUBSYSTEM: Pyruvate Metabolism
reactant: 320377
reversible: false

320413
type: SpeciesReference
stoichiometry: 1.0
species: 378218

320365
type: SpeciesReference
stoichiometry: 1.0
species: 378155

382349
type: LocalParameter
units: 304591
value: 0.0

382347
type: LocalParameter
units: 304591
value: 0.0

382345
type: LocalParameter
units: 304591
value: 1000.0

382343
type: LocalParameter
units: 304591
value: 0.0

320401
type: SpeciesReference
stoichiometry: 1.0
species: 378200

320389
type: SpeciesReference
stoichiometry: 1.0
species: 378077

320377
type: SpeciesReference
stoichiometry: 1.0
species: 378212

379888
type: Reaction
kinetic law: 326745
reactant: 326733
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Citrateexchange

383286
type: LocalParameter
units: 304591
value: 0.0

383285
type: LocalParameter
units: 304591
value: 0.0

383284
type: LocalParameter
units: 304591
value: 0.0

383283
type: LocalParameter
units: 304591
value: -1000.0

326733
type: SpeciesReference
stoichiometry: 1.0
species: 377805

379491
type: Reaction
kinetic law: 322407
product: 322395
reactant: 322383
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: Acetylcholintransport,nucleartrhoughpores

382630
type: LocalParameter
units: 304591
value: 0.0

382628
type: LocalParameter
units: 304591
value: 0.0

382626
type: LocalParameter
units: 304591
value: 1000.0

382624
type: LocalParameter
units: 304591
value: -1000.0

322395
type: SpeciesReference
stoichiometry: 1.0
species: 377682

322383
type: SpeciesReference
stoichiometry: 1.0
species: 377685