MODEL1008120006
type: SBMLModel
reaction: 034276
reaction: 032402
species: 731948
species: 736243
species: 736801
reaction: 040260
species: 733503
species: 750695
species: 744096
species: 744700
reaction: 031753
species: 741947
species: 753700
species: 733678
species: 729738
species: 735059
species: 744277
reaction: 041154
species: 737215
reaction: 031717
reaction: 038489
species: 747613
species: 753834
reaction: 037460
species: 752569
species: 750116
reaction: 038318
reaction: 031162
reaction: 036229
species: 727807
species: 750878
reaction: 032811
species: 735865
species: 734103
species: 733165
species: 737163
species: 729416
reaction: 032078
species: 745435
reaction: 036965
species: 735999
species: 751615
species: 727492
reaction: 034517
species: 743396
species: 735950
reaction: 033209
species: 745868
reaction: 037158
species: 751094
species: 740421
species: 748073
reaction: 038064
species: 745880
reaction: 036338
species: 739987
species: 731030
reaction: 040308
reaction: 037170
species: 746327
species: 734902
species: 747430
species: 726343
species: 729078
reaction: 034926
species: 736183
species: 737955
reaction: 033064
species: 732465
species: 739389
species: 737127
reaction: 036350
reaction: 035119
species: 751687
reaction: 039695
reaction: 038876
reaction: 037435
species: 741995
species: 727214

034276
type: Reaction
is: http://identifiers.org/ec-code/3.1.6.8
name: Arylsulfatase A
reversible: false
product: 788433
reactant: 788409
product: 788445
fast: false
product: 788457
is: ENSCAFG00000000566.2
notes: R_ARSA subsystem: Sphingolipid Metabolism R_ARSA equation: [l] : h2o + sgalside_hs --> galside_hs + h + so4
reactant: 788421

788433
type: SpeciesReference
stoichiometry: 1.0
species: 751227

751227
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Sulfate_O4S

726101
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

788409
type: SpeciesReference
stoichiometry: 1.0
species: 751142

751142
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: sulfatide galactocerebroside (homo sapiens)_C24H45NO10SFULLRCO

788445
type: SpeciesReference
stoichiometry: 1.0
species: 741296

741296
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: H+_H

788457
type: SpeciesReference
stoichiometry: 1.0
species: 739377

739377
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: galactocerebroside (homo sapiens)_C24H46NO7FULLRCO

788421
type: SpeciesReference
stoichiometry: 1.0
species: 741187

741187
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: H2O_H2O

032402
type: Reaction
reversible: true
name: calcium / sodium antiporter (1:3), reversible
is: ENSCAFG00000023592.1
reactant: 772847
is: ENSCAFG00000004140.2
notes: R_CAt7r subsystem: Transport, Extracellular R_CAt7r equation: ca2[c] + (3) na1[e] <==> ca2[e] + (3) na1[c]
product: 772859
product: 772871
fast: false
is: ENSCAFG00000008218.2
is: ENSCAFG00000016611.2
is: ENSCAFG00000006475.2
reactant: 772835

772847
type: SpeciesReference
stoichiometry: 3.0
species: 746930

746930
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Sodium_Na

726077
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

772859
type: SpeciesReference
stoichiometry: 1.0
species: 733009

733009
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Calcium_Ca

772871
type: SpeciesReference
stoichiometry: 3.0
species: 746918

746918
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Sodium_Na

726053
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

772835
type: SpeciesReference
stoichiometry: 1.0
species: 732997

732997
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Calcium_Ca

731948
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: alpha-Pinene-oxide_C10H16O

736243
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dehydroascorbate_C6H6O6

736801
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Deamino-NAD+_C21H24N6O15P2

726125
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

040260
type: Reaction
notes: R_PIt7 subsystem: Transport, Extracellular R_PIt7 equation: (3) na1[e] + pi[e] <==> (3) na1[c] + pi[c]
reactant: 845283
reactant: 845295
reversible: true
fast: false
name: phosphate transport in/out via three Na+ symporter
is: ENSCAFG00000016417.2
product: 845319
product: 845307
is: ENSCAFG00000016412.2

845283
type: SpeciesReference
stoichiometry: 3.0
species: 746930

845295
type: SpeciesReference
stoichiometry: 1.0
species: 749213

749213
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Phosphate_HO4P

845319
type: SpeciesReference
stoichiometry: 3.0
species: 746918

845307
type: SpeciesReference
stoichiometry: 1.0
species: 749200

749200
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Phosphate_HO4P

733503
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137

726137
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

750695
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Ribulose 5-phosphate_C5H9O8P

744096
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked), degradation product 1_C70H113N5O59S3X

744700
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Lactaldehyde_C3H6O2

031753
type: Reaction
notes: R_ASP1DC subsystem: beta-Alanine metabolism R_ASP1DC equation: [c] : asp-L + h --> ala-B + co2 R_3SALACBOXL subsystem: Taurine and hypotaurine metabolism R_3SALACBOXL equation: [c] : 3sala + h --> co2 + hyptaur R_GLUDC subsystem: Glutamate metabolism R_GLUDC equation: [c] : glu-L + h --> 4abut + co2 R_LCYSTCBOXL subsystem: Taurine and hypotaurine metabolism R_LCYSTCBOXL equation: [c] : Lcyst + h --> co2 + taur
reactant: 766485
is: http://identifiers.org/ec-code/4.1.1.15
reactant: 766497
fast: false
product: 766570
reactant: 766509
product: 766594
is: ENSCAFG00000012560.2
reactant: 766534
reactant: 766521
product: 766546
is: ENSCAFG00000000089.2
product: 766582
product: 766558
is: http://identifiers.org/ec-code/4.1.1.11
reversible: false

766485
type: SpeciesReference
stoichiometry: 1.0
species: 729307

729307
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Cysteate_C3H6NO5S

766497
type: SpeciesReference
stoichiometry: 1.0
species: 727795

727795
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Sulfino-L-alanine_C3H5NO4S

766570
type: SpeciesReference
stoichiometry: 1.0
species: 742576

742576
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Hypotaurine_C2H6NO2S

766509
type: SpeciesReference
stoichiometry: 1.0
species: 739987

739987
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Glutamate_C5H8NO4

766594
type: SpeciesReference
stoichiometry: 1.0
species: 731465

731465
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: beta-Alanine_C3H7NO2

766534
type: SpeciesReference
stoichiometry: 4.0
species: 741259

741259
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: H+_H

766521
type: SpeciesReference
stoichiometry: 1.0
species: 732404

732404
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Aspartate_C4H6NO4

766546
type: SpeciesReference
stoichiometry: 1.0
species: 751796

751796
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Taurine_C2H7NO3S

766582
type: SpeciesReference
stoichiometry: 4.0
species: 733981

733981
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: CO2_CO2

766558
type: SpeciesReference
stoichiometry: 1.0
species: 727979

727979
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Aminobutanoate_C4H9NO2

741947
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: heptadecanoyl carnitine_C24H47NO4

753700
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: vaccenyl coenzyme A_C39H64N7O17P3S

733678
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Citrate_C6H5O7

729738
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: R total Coenzyme A_CO2FULLRC21H31N7O15P3S

735059
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate precursor (GalNAc-GlcA-(Gal)2-Xyl-L-Ser (protein))_C31H49NO25X

726089
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

744277
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 4_C53H86N4O38X

041154
type: Reaction
product: 855146
product: 855134
fast: false
reactant: 855122
product: 855170
reversible: false
notes: R_HMGLx subsystem: Cholesterol Metabolism R_HMGLx equation: [x] : hmgcoa --> acac + accoa R_HMGLm subsystem: Cholesterol Metabolism R_HMGLm equation: [m] : hmgcoa --> acac + accoa
is: ENSCAFG00000013085.2
is: http://identifiers.org/ec-code/4.1.3.4
reactant: 855110
product: 855158

855146
type: SpeciesReference
stoichiometry: 1.0
species: 730148

730148
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Acetyl-CoA_C23H34N7O17P3S

726113
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

855134
type: SpeciesReference
stoichiometry: 1.0
species: 730052

730052
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Acetoacetate_C4H5O3

855122
type: SpeciesReference
stoichiometry: 1.0
species: 741850

741850
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137

855170
type: SpeciesReference
stoichiometry: 1.0
species: 730184

730184
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Acetyl-CoA_C23H34N7O17P3S

855110
type: SpeciesReference
stoichiometry: 1.0
species: 741826

741826
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113

855158
type: SpeciesReference
stoichiometry: 1.0
species: 730064

730064
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Acetoacetate_C4H5O3

737215
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dTTP_C10H13N2O14P3

031717
type: Reaction
product: 765560
product: 765536
reactant: 765500
reactant: 765476
product: 765596
product: 765548
reversible: false
fast: false
is: ENSCAFG00000002873.2
is: ENSCAFG00000002871.2
product: 765572
reactant: 765512
notes: R_DOPASULT subsystem: Tyrosine metabolism R_DOPASULT equation: [c] : dopa + paps --> dopasf + h + pap R_4NPHSULT subsystem: CYP Metabolism R_4NPHSULT equation: [c] : 4nph + paps --> 4nphsf + h + pap R_TYMSULT subsystem: Tyrosine metabolism R_TYMSULT equation: [c] : paps + tym --> h + pap + tymsf R_NRPPHRSULT subsystem: Tyrosine metabolism R_NRPPHRSULT equation: [c] : nrpphr + paps --> h + nrpphrsf + pap
reactant: 765488
reactant: 765524
is: http://identifiers.org/ec-code/2.8.2.1
product: 765584

765560
type: SpeciesReference
stoichiometry: 1.0
species: 737019

737019
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dopamine 3-O-sulfate_C8H11NO5S

765536
type: SpeciesReference
stoichiometry: 4.0
species: 748651

748651
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Adenosine 3',5'-bisphosphate_C10H11N5O10P2

765500
type: SpeciesReference
stoichiometry: 1.0
species: 728269

728269
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Nitrophenol_C6H5NO3

765476
type: SpeciesReference
stoichiometry: 1.0
species: 753047

753047
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Tyramine_C8H12NO

765596
type: SpeciesReference
stoichiometry: 4.0
species: 741259

765548
type: SpeciesReference
stoichiometry: 1.0
species: 747577

747577
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Sulfate derivative of norepinephrine_C8H11NO6S

765572
type: SpeciesReference
stoichiometry: 1.0
species: 753059

753059
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Tyramine O-sulfate_C8H11NO4S

765512
type: SpeciesReference
stoichiometry: 1.0
species: 736983

736983
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dopamine_C8H12NO2

765488
type: SpeciesReference
stoichiometry: 1.0
species: 747553

747553
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Norepinephrine_C8H12NO3

765524
type: SpeciesReference
stoichiometry: 4.0
species: 748675

748675
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3'-Phosphoadenylyl sulfate_C10H11N5O13P2S

765584
type: SpeciesReference
stoichiometry: 1.0
species: 728281

728281
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Nitrophenyl sulfate_C6H4NO6S

038489
type: Reaction
is: http://identifiers.org/ec-code/2.7.4.3
reactant: 829506
is: ENSCAFG00000013746.2
is: ENSCAFG00000012522.2
name: adenylate kinase, mitochondrial
product: 829530
is: ENSCAFG00000010390.2
reversible: true
fast: false
is: ENSCAFG00000000211.1
notes: R_ADK1m subsystem: Nucleotides R_ADK1m equation: [m] : amp + atp <==> (2) adp
is: ENSCAFG00000015156.2
reactant: 829518
is: ENSCAFG00000018611.2

829506
type: SpeciesReference
stoichiometry: 1.0
species: 731803

731803
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: AMP_C10H12N5O7P

829530
type: SpeciesReference
stoichiometry: 2.0
species: 730946

730946
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: ADP_C10H12N5O10P2

829518
type: SpeciesReference
stoichiometry: 1.0
species: 732465

732465
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: ATP_C10H12N5O13P3

747613
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: nervonyl coenzyme A_C45H76N7O17P3S

753834
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: omega hydroxy hexadecanoate (n-C16:0)_C16H31O3

037460
type: Reaction
reactant: 818653
product: 818762
reactant: 818557
is: ENSCAFG00000002400.1
product: 818713
product: 818798
fast: false
reversible: false
reactant: 818593
reactant: 818581
product: 818822
reactant: 818629
is: http://identifiers.org/ec-code/1.2.1.21
is: http://identifiers.org/ec-code/1.2.1.3
reactant: 818641
product: 818834
is: ENSCAFG00000008683.2
product: 818810
product: 818749
product: 818786
reactant: 818689
reactant: 818677
product: 818774
reactant: 818617
product: 818846
product: 818725
product: 818859
reactant: 818665
reactant: 818701
reactant: 818605
reactant: 818569
notes: R_LCADim subsystem: Pyruvate Metabolism R_LCADim equation: [m] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDDm subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDDm equation: [m] : gcald + h2o + nad --> glyclt + (2) h + nadh R_BAMPPALDOXm subsystem: beta-Alanine metabolism R_BAMPPALDOXm equation: [m] : bamppald + h2o + nad --> ala-B + (2) h + nadh R_ALDD2xm subsystem: Glycolysis/Gluconeogenesis R_ALDD2xm equation: [m] : acald + h2o + nad --> ac + (2) h + nadh R_NABTNOm subsystem: Arginine and Proline Metabolism R_NABTNOm equation: [m] : h2o + n4abutn + nad --> 4aabutn + (2) h + nadh R_PYLALDOXm subsystem: Limonene and pinene degradation R_PYLALDOXm equation: [m] : h2o + nad + pylald --> (2) h + nadh + peracd R_LCADi_Dm subsystem: Pyruvate Metabolism R_LCADi_Dm equation: [m] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_IMACTD_m subsystem: Histidine Metabolism R_IMACTD_m equation: [m] : h2o + im4act + nad --> (2) h + im4ac + nadh R_ALDD20xm subsystem: Tryptophan metabolism R_ALDD20xm equation: [m] : h2o + id3acald + nad --> (2) h + ind3ac + nadh R_5HOXINDACTOXm subsystem: Tryptophan metabolism R_5HOXINDACTOXm equation: [m] : 5hoxindact + h2o + nad --> 5hoxindoa + (2) h + nadh R_GLACOm subsystem: Ascorbate and Aldarate Metabolism R_GLACOm equation: [m] : glac + (2) h2o + nad --> glcr + (3) h + nadh
product: 818737

818653
type: SpeciesReference
stoichiometry: 1.0
species: 739802

739802
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: D-glucurono-6,3-lactone_C6H8O6

818762
type: SpeciesReference
stoichiometry: 1.0
species: 730016

730016
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Acetate_C2H3O2

818557
type: SpeciesReference
stoichiometry: 1.0
species: 732549

732549
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: beta-Aminopropion aldehyde_C3H8NO

818713
type: SpeciesReference
stoichiometry: 1.0
species: 727967

727967
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _4-Acetamidobutanoate_C6H10NO3

818798
type: SpeciesReference
stoichiometry: 1.0
species: 731489

731489
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: beta-Alanine_C3H7NO2

818593
type: SpeciesReference
stoichiometry: 1.0
species: 746894

746894
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: N4-Acetylaminobutanal_C6H11NO2

818581
type: SpeciesReference
stoichiometry: 1.0
species: 730088

730088
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Acetaldehyde_C2H4O

818822
type: SpeciesReference
stoichiometry: 1.0
species: 744663

744663
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Lactate_C3H5O3

818629
type: SpeciesReference
stoichiometry: 1.0
species: 742672

742672
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Indole-3-acetaldehyde_C10H9NO

818641
type: SpeciesReference
stoichiometry: 1.0
species: 744688

744688
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: D-Lactaldehyde_C3H6O2

818834
type: SpeciesReference
stoichiometry: 23.0
species: 741308

741308
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: H+_H

818810
type: SpeciesReference
stoichiometry: 1.0
species: 742807

742807
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Imidazole-4-acetate_C5H5N2O2

818749
type: SpeciesReference
stoichiometry: 1.0
species: 744624

744624
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: D-Lactate_C3H5O3

818786
type: SpeciesReference
stoichiometry: 1.0
species: 748971

748971
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Perillic acid_C10H13O2

818689
type: SpeciesReference
stoichiometry: 11.0
species: 747002

747002
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

818677
type: SpeciesReference
stoichiometry: 1.0
species: 744712

744712
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Lactaldehyde_C3H6O2

818774
type: SpeciesReference
stoichiometry: 1.0
species: 742880

742880
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Indole-3-acetate_C10H8NO2

818617
type: SpeciesReference
stoichiometry: 1.0
species: 742831

742831
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Imidazole-4-acetaldehyde_C5H6N2O

818846
type: SpeciesReference
stoichiometry: 1.0
species: 739889

739889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: D-Glucarate_C6H8O8

818725
type: SpeciesReference
stoichiometry: 1.0
species: 740361

740361
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Glycolate_C2H3O3

818859
type: SpeciesReference
stoichiometry: 11.0
species: 747062

747062
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

818665
type: SpeciesReference
stoichiometry: 1.0
species: 750357

750357
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Perillyl aldehyde_C10H14O

818701
type: SpeciesReference
stoichiometry: 1.0
species: 739499

739499
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Glycolaldehyde_C2H4O2

818605
type: SpeciesReference
stoichiometry: 1.0
species: 728680

728680
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _5-Hydroxyindoleacetaldehyde_C10H9NO2

818569
type: SpeciesReference
stoichiometry: 12.0
species: 741199

741199
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: H2O_H2O

818737
type: SpeciesReference
stoichiometry: 1.0
species: 728704

728704
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _5-Hydroxyindoleacetate_C10H8NO3

752569
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Thymidine_C10H14N2O5

750116
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Propenoyl-CoA_C24H34N7O17P3S

038318
type: Reaction
product: 828098
fast: false
reactant: 828026
reactant: 828062
product: 828110
reactant: 828086
reactant: 828050
reversible: false
product: 828134
product: 828158
product: 828122
reactant: 828038
product: 828146
is: ENSCAFG00000011224.2
reactant: 828074
is: http://identifiers.org/ec-code/1.4.3.3
notes: R_DPROOp subsystem: Arginine and Proline Metabolism R_DPROOp equation: [x] : o2 + pro-D --> 1p2cbxl + h + h2o2 R_DALAOXx subsystem: D-alanine metabolism R_DALAOXx equation: [x] : ala-D + h2o + o2 --> h2o2 + nh4 + pyr R_DARGOp subsystem: D-arg and D-orn metabolism R_DARGOp equation: [x] : arg-D + h2o + o2 --> 5g2oxpt + h2o2 + nh4 R_DORNOp subsystem: D-arg and D-orn metabolism R_DORNOp equation: [x] : h2o + o2 + orn-D --> 5a2opntn + h2o2 + nh4
product: 828170

828098
type: SpeciesReference
stoichiometry: 1.0
species: 728426

728426
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _5-Amino-2-oxopentanoate_C5H9NO3

828026
type: SpeciesReference
stoichiometry: 3.0
species: 741235

741235
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: H2O_H2O

828062
type: SpeciesReference
stoichiometry: 1.0
species: 731537

731537
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: D-Alanine_C3H7NO2

828110
type: SpeciesReference
stoichiometry: 1.0
species: 728643

728643
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _5-Guanidino-2-oxopentanoate_C6H11N3O3

828086
type: SpeciesReference
stoichiometry: 1.0
species: 749863

749863
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: D-Proline_C5H9NO2

828050
type: SpeciesReference
stoichiometry: 1.0
species: 748194

748194
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: D-Ornithine_C5H13N2O2

828134
type: SpeciesReference
stoichiometry: 1.0
species: 726644

726644
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _1-Pyrroline-2-carboxylate_C5H6NO2

828158
type: SpeciesReference
stoichiometry: 3.0
species: 747355

747355
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Ammonium_H4N

828122
type: SpeciesReference
stoichiometry: 4.0
species: 741139

741139
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Hydrogen peroxide_H2O2

828038
type: SpeciesReference
stoichiometry: 4.0
species: 747758

747758
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: O2_O2

828146
type: SpeciesReference
stoichiometry: 1.0
species: 741344

741344
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: H+_H

828074
type: SpeciesReference
stoichiometry: 1.0
species: 732248

732248
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: D-Arginine_C6H15N4O2

828170
type: SpeciesReference
stoichiometry: 1.0
species: 750405

750405
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Pyruvate_C3H3O3

031162
type: Reaction
reactant: 760932
reactant: 760944
notes: R_M4BET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4BET2er equation: [r] : mem2emgacpail_hs + pe_hs --> dag_hs + m(em)3gacpail_hs R_H6_APOS_ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6_APOS_ET2er equation: [r] : em3gacpail_hs + pe_hs --> dag_hs + emem2gacpail_hs R_H7ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7ET2er equation: [r] : em2emgacpail_hs + pe_hs --> dag_hs + gpi_hs
product: 760993
reactant: 760908
product: 760956
product: 760980
fast: false
is: ENSCAFG00000016795.2
reactant: 760920
product: 760968
reversible: false

760932
type: SpeciesReference
stoichiometry: 1.0
species: 746146

746146
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: ({[(mannosyl),(phosphoethanolaminyl)]-dimannosyl},{phosphoethanolaminyl})-mannosyl-glucosaminyl-acylphosphatidylinositol (M4B)_C59H110N3O40P3FULLRCO2FULLR2CO2

726065
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

760944
type: SpeciesReference
stoichiometry: 1.0
species: 737618

737618
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (phosphoethanolaminyl-dimannosyl),(phosphoethanolaminyl)-mannosyl-glucosaminyl-acylphosphatidylinositol (H7)_C53H100N3O35P3FULLRCO2FULLR2CO2

760993
type: SpeciesReference
stoichiometry: 1.0
species: 745832

745832
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: mannosyl-3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol (M4A)_C61H116N4O43P4FULLRCO2FULLR2CO2

760908
type: SpeciesReference
stoichiometry: 1.0
species: 737642

737642
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: phosphoethanolaminyl-trimannosyl-glucosaminyl-acylphosphatidylinositol (H6')_C51H94N2O32P2FULLRCO2FULLR2CO2

760956
type: SpeciesReference
stoichiometry: 1.0
species: 740651

740651
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: glycophosphatidylinositol (GPI) anchor precursor (3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol) (H8)_C55H106N4O38P4FULLRCO2FULLR2CO2

760980
type: SpeciesReference
stoichiometry: 1.0
species: 737654

737654
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (phosphoethanolaminyl-mannosyl),(phosphoethanolaminyl)-dimannosyl-glucosaminyl-acylphosphatidylinositol (H7')_C53H100N3O35P3FULLRCO2FULLR2CO2

760920
type: SpeciesReference
stoichiometry: 3.0
species: 748886

748886
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2

760968
type: SpeciesReference
stoichiometry: 3.0
species: 735445

735445
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2

036229
type: Reaction
is: ENSCAFG00000011504.2
product: 807724
reactant: 807700
is: http://identifiers.org/ec-code/1.1.1.205
reversible: false
product: 807736
fast: false
is: ENSCAFG00000011933.2
product: 807748
notes: R_IMPD subsystem: Nucleotides R_IMPD equation: [c] : h2o + imp + nad --> h + nadh + xmp
reactant: 807688
name: IMP dehydrogenase
reactant: 807712

807724
type: SpeciesReference
stoichiometry: 1.0
species: 753894

753894
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Xanthosine 5'-phosphate_C10H11N4O9P

807700
type: SpeciesReference
stoichiometry: 1.0
species: 742843

742843
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: IMP_C10H11N4O8P

807736
type: SpeciesReference
stoichiometry: 1.0
species: 741259

807748
type: SpeciesReference
stoichiometry: 1.0
species: 747050

747050
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

807688
type: SpeciesReference
stoichiometry: 1.0
species: 746978

746978
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

807712
type: SpeciesReference
stoichiometry: 1.0
species: 741151

741151
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: H2O_H2O

727807
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3-Sulfino-L-alanine_C3H5NO4S

750878
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Sarcosine_C3H7NO2

032811
type: Reaction
is: http://identifiers.org/ec-code/2.5.1.17
modifier: 776514
modifier: 776526
product: 776478
modifier: 776502
is: ENSCAFG00000007682.2
notes: R_CBLATm subsystem: Vitamin B12 Metabolism R_CBLATm equation: [m] : atp + cbl1 + h <==> adocbl + pppi R_CBL2tm subsystem: Transport, Mitochondrial R_CBL2tm equation: cbl2[c] --> cbl2[m]
modifier: 776539
reversible: false
fast: false
reactant: 776466
modifier: 776490

733117
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Cob(I)alamin_C62H88CoN13O14P

749622
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Inorganic triphosphate_HO10P3

776478
type: SpeciesReference
stoichiometry: 1.0
species: 733141

733141
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Cob(II)alamin_C62H92CoN13O14P

730910
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Adenosylcobalamin_C72H100CoN18O17P

776466
type: SpeciesReference
stoichiometry: 1.0
species: 733129

733129
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Cob(II)alamin_C62H92CoN13O14P

735865
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: debrisoquine_C10H14N3

734103
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Coenzyme A_C21H32N7O16P3S

733165
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Carbamoyl phosphate_CH2NO5P

737163
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: dTMP_C10H13N2O8P

729416
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Protein N6,N6-dimethyl-L-lysine_C2H7X

032078
type: Reaction
fast: false
is: ENSCAFG00000001912.2
is: http://identifiers.org/ec-code/3.6.1.17
product: 769446
reactant: 769409
reactant: 769397
reversible: false
product: 769422
name: Ap4A hydrolase, asymmetrically
product: 769434
notes: R_AP4AH1 subsystem: Nucleotides R_AP4AH1 equation: [c] : ap4a + h2o --> amp + atp + (2) h

769446
type: SpeciesReference
stoichiometry: 2.0
species: 741259

769409
type: SpeciesReference
stoichiometry: 1.0
species: 731936

731936
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: P1,P4-Bis(5'-adenosyl) tetraphosphate_C20H24N10O19P4

769397
type: SpeciesReference
stoichiometry: 1.0
species: 741151

769422
type: SpeciesReference
stoichiometry: 1.0
species: 732441

732441
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: ATP_C10H12N5O13P3

769434
type: SpeciesReference
stoichiometry: 1.0
species: 731755

731755
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: AMP_C10H12N5O7P

745435
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: L-Lysine_C6H15N2O2

036965
type: Reaction
notes: R_UDPGLCtg subsystem: Transport, Golgi Apparatus R_UDPGLCtg equation: udpg[c] + ump[g] <==> udpg[g] + ump[c] R_UGLCNACtg subsystem: Transport, Golgi Apparatus R_UGLCNACtg equation: uacgam[c] + ump[g] <==> uacgam[g] + ump[c]
fast: false
reversible: true
reactant: 813288
reactant: 813312
product: 813349
reactant: 813300
is: ENSCAFG00000001216.2
product: 813337
product: 813325

813288
type: SpeciesReference
stoichiometry: 1.0
species: 753266

753266
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: UDPglucose_C15H22N2O17P2

813312
type: SpeciesReference
stoichiometry: 2.0
species: 753423

753423
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: UMP_C9H11N2O9P

813349
type: SpeciesReference
stoichiometry: 1.0
species: 753278

753278
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: UDPglucose_C15H22N2O17P2

813300
type: SpeciesReference
stoichiometry: 1.0
species: 753109

753109
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053

813337
type: SpeciesReference
stoichiometry: 1.0
species: 753121

753121
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089

813325
type: SpeciesReference
stoichiometry: 2.0
species: 753399

753399
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: UMP_C9H11N2O9P

735999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: dGMP_C10H12N5O7P

751615
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: stearidonyl carnitine_C25H41NO4

727492
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Hydroxy-N6,N6,N6-trimethyl-L-lysine_C9H20N2O3

034517
type: Reaction
notes: R_DHPR subsystem: Tetrahydrobiopterin R_DHPR equation: [c] : dhbpt + h + nadh --> nad + thbpt
reactant: 790738
product: 790786
reactant: 790750
reversible: false
fast: false
name: _6,7-dihydropteridine reductase
reactant: 790762
product: 790774
is: ENSCAFG00000015113.2

790738
type: SpeciesReference
stoichiometry: 1.0
species: 736135

736135
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _6,7-Dihydrobiopterin_C9H13N5O3

790786
type: SpeciesReference
stoichiometry: 1.0
species: 746978

790750
type: SpeciesReference
stoichiometry: 1.0
species: 741259

790762
type: SpeciesReference
stoichiometry: 1.0
species: 747050

790774
type: SpeciesReference
stoichiometry: 1.0
species: 752229

752229
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Tetrahydrobiopterin_C9H15N5O3

743396
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 30_C90H147N6O75S3

735950
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: dGDP_C10H12N5O10P2

033209
type: Reaction
fast: false
notes: R_PIter subsystem: Transport, Endoplasmic Reticular R_PIter equation: pi[r] <==> pi[c] R_G6Pter subsystem: Transport, Endoplasmic Reticular R_G6Pter equation: g6p[c] <==> g6p[r]
reversible: true
reactant: 779158
product: 779182
is: ENSCAFG00000012380.2
product: 779170
reactant: 779146

779158
type: SpeciesReference
stoichiometry: 1.0
species: 739027

739027
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Glucose 6-phosphate_C6H11O9P

779182
type: SpeciesReference
stoichiometry: 1.0
species: 739039

739039
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: D-Glucose 6-phosphate_C6H11O9P

779170
type: SpeciesReference
stoichiometry: 1.0
species: 749200

779146
type: SpeciesReference
stoichiometry: 1.0
species: 749273

749273
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Phosphate_HO4P

745868
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: monoacylglycerol 2 (homo sapiens)_C3H7O2FULLR2CO2

037158
type: Reaction
product: 815497
reactant: 815485
notes: R_FRUt1r subsystem: Transport, Extracellular R_FRUt1r equation: fru[e] <==> fru[c]
is: ENSCAFG00000016244.2
fast: false
reversible: true
name: D-fructose transport in via uniport

815497
type: SpeciesReference
stoichiometry: 1.0
species: 738474

738474
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Fructose_C6H12O6

815485
type: SpeciesReference
stoichiometry: 1.0
species: 738486

738486
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: D-Fructose_C6H12O6

751094
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Serine_C3H7NO3

740421
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: glycogen, structure 3 (glycogenin-7[1,4-Glc])_C42H71O36X

748073
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113

038064
type: Reaction
product: 826171
product: 826184
product: 826145
is: ENSCAFG00000020001.2
reactant: 826121
product: 826158
is: http://identifiers.org/ec-code/3.6.1.43
fast: false
reversible: false
reactant: 826133
reactant: 826109
notes: R_DOLDPP_Ler subsystem: N-Glycan Biosynthesis R_DOLDPP_Ler equation: [r] : (0.1) doldp_L + h2o --> (0.1) dolp_L + h + pi R_DOLDPP_Uer subsystem: N-Glycan Biosynthesis R_DOLDPP_Uer equation: [r] : (0.1) doldp_U + h2o --> (0.1) dolp_U + h + pi

826171
type: SpeciesReference
stoichiometry: 1.0
species: 736971

736971
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dolichol phosphate, human uterine homolog_C1025H1670O40P10

826184
type: SpeciesReference
stoichiometry: 2.0
species: 741332

741332
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: H+_H

826145
type: SpeciesReference
stoichiometry: 1.0
species: 736947

736947
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dolichol phosphate, human liver homolog_C1080H1758O40P10

826121
type: SpeciesReference
stoichiometry: 2.0
species: 741223

741223
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: H2O_H2O

826158
type: SpeciesReference
stoichiometry: 2.0
species: 749273

826133
type: SpeciesReference
stoichiometry: 1.0
species: 736825

736825
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dolichol diphosphate, human uterine homolog_C1025H1670O70P20

826109
type: SpeciesReference
stoichiometry: 1.0
species: 736813

736813
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dolichol diphosphate, human liver homolog_C1080H1758O70P20

745880
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Malonyl-[acyl-carrier protein]_C14H22N2O10PRS

036338
type: Reaction
product: 808409
fast: false
product: 808397
modifier: 808433
product: 808385
reactant: 808361
reversible: false
product: 808373
is: http://identifiers.org/ec-code/2.3.1.9
modifier: 808421
is: ENSCAFG00000000720.2
modifier: 808445
reactant: 808349
notes: R_ACACT1r subsystem: Tryptophan metabolism R_ACACT1r equation: [c] : (2) accoa <==> aacoa + coa R_ACACT1x subsystem: Cholesterol Metabolism R_ACACT1x equation: [x] : (2) accoa --> aacoa + coa R_ACACT1 subsystem: Cholesterol Metabolism R_ACACT1 equation: [c] : (2) accoa --> aacoa + coa

808409
type: SpeciesReference
stoichiometry: 1.0
species: 729931

729931
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Acetoacetyl-CoA_C25H36N7O18P3S

808397
type: SpeciesReference
stoichiometry: 1.0
species: 729907

729907
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Acetoacetyl-CoA_C25H36N7O18P3S

808385
type: SpeciesReference
stoichiometry: 1.0
species: 734127

734127
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Coenzyme A_C21H32N7O16P3S

808361
type: SpeciesReference
stoichiometry: 2.0
species: 730184

808373
type: SpeciesReference
stoichiometry: 1.0
species: 734054

734054
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Coenzyme A_C21H32N7O16P3S

730124
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Acetyl-CoA_C23H34N7O17P3S

808349
type: SpeciesReference
stoichiometry: 2.0
species: 730124

731030
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: ADPribose_C15H21N5O14P2

040308
type: Reaction
name: beta-D-Glucosyl-2-coumarinate glucohydrolase
is: http://identifiers.org/ec-code/3.2.1.21
product: 845487
reactant: 845451
fast: false
is: ENSCAFG00000016529.2
reactant: 845463
product: 845475
product: 845499
notes: R_BDG2HCGHD subsystem: Stilbene, coumarine and lignin biosynthesis R_BDG2HCGHD equation: [c] : bdg2hc + h2o --> 2coum + glc-D + h
reversible: false

845487
type: SpeciesReference
stoichiometry: 1.0
species: 739815

739815
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Glucose_C6H12O6

845451
type: SpeciesReference
stoichiometry: 1.0
species: 741151

845463
type: SpeciesReference
stoichiometry: 1.0
species: 732561

732561
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cis-beta-D-Glucosyl-2-hydroxycinnamate_C15H18O8

845475
type: SpeciesReference
stoichiometry: 1.0
species: 726826

726826
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cis-2-Hydroxy cinnamate_C9H7O3

845499
type: SpeciesReference
stoichiometry: 1.0
species: 741259

037170
type: Reaction
notes: R_AKR1D2 subsystem: Bile Acid Biosynthesis R_AKR1D2 equation: [c] : h + nadph + xoldiolone --> nadp + xoldioloneh R_AKR1D subsystem: Bile Acid Biosynthesis R_AKR1D equation: [c] : h + nadph + xol7aone --> nadp + xol7ah
product: 815557
reactant: 815533
reactant: 815521
product: 815569
is: ENSCAFG00000015184.2
reversible: false
reactant: 815545
fast: false
product: 815581
reactant: 815509

815557
type: SpeciesReference
stoichiometry: 1.0
species: 754015

754015
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _7alpha-Hydroxy-5beta-cholestan-3-one_C27H46O2

815533
type: SpeciesReference
stoichiometry: 2.0
species: 741259

815521
type: SpeciesReference
stoichiometry: 1.0
species: 754027

754027
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _7alpha-Hydroxycholest-4-en-3-one_C27H44O2

815569
type: SpeciesReference
stoichiometry: 2.0
species: 747099

747099
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

815545
type: SpeciesReference
stoichiometry: 2.0
species: 747173

747173
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

815581
type: SpeciesReference
stoichiometry: 1.0
species: 754075

754075
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one_C27H46O3

815509
type: SpeciesReference
stoichiometry: 1.0
species: 754051

754051
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _7alpha,12alpha-Dihydroxycholest-4-en-3-one_C27H44O3

746327
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _5,10-Methenyltetrahydrofolate_C20H20N7O6

734902
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 1_C45H65N2O52S5

747430
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C42H70N3O30X

726343
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _11-Deoxycortisol_C21H30O4

729078
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: hexaglutamyl folate (THF)_C44H51N12O21

034926
type: Reaction
reactant: 794103
reactant: 794115
product: 794223
fast: false
product: 794211
product: 794199
reactant: 794139
notes: R_S6T24g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T24g equation: [g] : cs_e_pre4 + paps --> cs_e_pre5b + h + pap R_S6T23g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T23g equation: [g] : cs_e_pre5a + paps --> cspg_e + h + pap R_S6T20g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T20g equation: [g] : cs_c_pre3 + paps --> cspg_c + h + pap R_S6T19g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T19g equation: [g] : cs_pre + (2) paps --> cs_c,d,e_pre1 + (2) h + (2) pap R_S6T22g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T22g equation: [g] : cs_a,b,e_pre1 + (2) paps --> cs_e_pre2 + (2) h + (2) pap R_S6T21g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T21g equation: [g] : cs_d_pre4 + paps --> cs_d_pre5 + h + pap
product: 794187
reactant: 794091
product: 794247
product: 794175
reactant: 794151
product: 794235
product: 794163
is: ENSCAFG00000014753.2
is: http://identifiers.org/ec-code/2.8.2.17
reactant: 794127
reactant: 794079
reversible: false

794103
type: SpeciesReference
stoichiometry: 1.0
species: 734755

734755
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate C (GalNAc6S-GlcA), precursor 3_C45H67N2O42S2X

794115
type: SpeciesReference
stoichiometry: 8.0
species: 748687

748687
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: _3'-Phosphoadenylyl sulfate_C10H11N5O13P2S

794223
type: SpeciesReference
stoichiometry: 1.0
species: 735047

735047
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5b_C45H64N2O51S5X

794211
type: SpeciesReference
stoichiometry: 8.0
species: 748663

748663
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Adenosine 3',5'-bisphosphate_C10H11N5O10P2

794199
type: SpeciesReference
stoichiometry: 1.0
species: 734890

734890
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 5_C45H65N2O48S4X

794139
type: SpeciesReference
stoichiometry: 1.0
species: 735059

794187
type: SpeciesReference
stoichiometry: 8.0
species: 741283

741283
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: H+_H

794091
type: SpeciesReference
stoichiometry: 1.0
species: 734477

734477
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate A (GalNAc4S-GlcA), B (IdoA2S-GalNAc4S), and E (GalNAc4,6diS-GlcA), precursor 1_C31H47NO31S2X

794247
type: SpeciesReference
stoichiometry: 1.0
species: 734999

734999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 2_C31H45NO37S4X

794175
type: SpeciesReference
stoichiometry: 1.0
species: 735119

735119
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate C (GalNAc6S-GlcA) proteoglycan_C45H66N2O45S3X

794151
type: SpeciesReference
stoichiometry: 1.0
species: 735023

735023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 4_C45H65N2O48S4X

794235
type: SpeciesReference
stoichiometry: 1.0
species: 735143

735143
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate E (GalNAc4,6diS-GlcA) proteoglycan_C45H63N2O54S6X

794163
type: SpeciesReference
stoichiometry: 1.0
species: 734658

734658
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate C (GalNAc6S-GlcA) and D (GlcNAc6S-GlcA2S), precursor 1_C31H47NO31S2X

794127
type: SpeciesReference
stoichiometry: 1.0
species: 735035

735035
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5a_C45H64N2O51S5X

794079
type: SpeciesReference
stoichiometry: 1.0
species: 734878

734878
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 4_C45H66N2O45S3X

736183
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065

737955
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Ethanol_C2H6O

033064
type: Reaction
product: 778384
reactant: 778360
reactant: 778348
product: 778372
is: ENSCAFG00000013498.2
is: ENSCAFG00000010165.2
name: glucose transport via sodium symport
is: ENSCAFG00000018237.2
reversible: true
fast: false
notes: R_GLCt4 subsystem: Transport, Extracellular R_GLCt4 equation: glc-D[e] + na1[e] <==> glc-D[c] + na1[c]

778384
type: SpeciesReference
stoichiometry: 1.0
species: 739815

778360
type: SpeciesReference
stoichiometry: 1.0
species: 739827

739827
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: D-Glucose_C6H12O6

778348
type: SpeciesReference
stoichiometry: 1.0
species: 746930

778372
type: SpeciesReference
stoichiometry: 1.0
species: 746918

739389
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Galactitol_C6H14O6

737127
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: dTDP_C10H13N2O11P2

036350
type: Reaction
notes: R_GLNtN1 subsystem: Transport, Extracellular R_GLNtN1 equation: gln-L[e] + h[c] + (2) na1[e] <==> gln-L[c] + h[e] + (2) na1[c] R_ASNtN1 subsystem: Transport, Extracellular R_ASNtN1 equation: asn-L[e] + h[c] + (2) na1[e] <==> asn-L[c] + h[e] + (2) na1[c] R_ALAtN1 subsystem: Transport, Extracellular R_ALAtN1 equation: ala-L[e] + h[c] + (2) na1[e] <==> ala-L[c] + h[e] + (2) na1[c] R_HIStN1 subsystem: Transport, Extracellular R_HIStN1 equation: h[c] + his-L[e] + (2) na1[e] <==> h[e] + his-L[c] + (2) na1[c]
reactant: 808517
reactant: 808457
reactant: 808481
reactant: 808493
product: 808589
reactant: 808505
product: 808577
fast: false
product: 808565
product: 808553
reversible: true
reactant: 808469
is: ENSCAFG00000010754.1
product: 808541
product: 808529

808517
type: SpeciesReference
stoichiometry: 4.0
species: 741259

808457
type: SpeciesReference
stoichiometry: 1.0
species: 741765

741765
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Histidine_C6H9N3O2

808481
type: SpeciesReference
stoichiometry: 1.0
species: 732344

732344
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Asparagine_C4H8N2O3

808493
type: SpeciesReference
stoichiometry: 8.0
species: 746930

808589
type: SpeciesReference
stoichiometry: 1.0
species: 731549

731549
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Alanine_C3H7NO2

808505
type: SpeciesReference
stoichiometry: 1.0
species: 739939

739939
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Glutamine_C5H10N2O3

808577
type: SpeciesReference
stoichiometry: 1.0
species: 732332

732332
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Asparagine_C4H8N2O3

808565
type: SpeciesReference
stoichiometry: 8.0
species: 746918

808553
type: SpeciesReference
stoichiometry: 1.0
species: 741753

741753
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Histidine_C6H9N3O2

808469
type: SpeciesReference
stoichiometry: 1.0
species: 731561

731561
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Alanine_C3H7NO2

808541
type: SpeciesReference
stoichiometry: 1.0
species: 739926

739926
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Glutamine_C5H10N2O3

808529
type: SpeciesReference
stoichiometry: 4.0
species: 741271

741271
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: H+_H

035119
type: Reaction
product: 795670
notes: R_FACOAL40im subsystem: Fatty acid activation R_FACOAL40im equation: [m] : atp + but + coa --> amp + btcoa + ppi
name: fatty-acid--CoA ligase (butanoate), mitochondrial
reactant: 795622
product: 795682
reactant: 795634
reactant: 795646
reversible: false
product: 795658
is: http://identifiers.org/ec-code/6.2.1.2
is: ENSCAFG00000024625.1
fast: false

795670
type: SpeciesReference
stoichiometry: 1.0
species: 732805

732805
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Butanoyl-CoA_C25H38N7O17P3S

795622
type: SpeciesReference
stoichiometry: 1.0
species: 732889

732889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Butyrate (n-C4:0)_C4H7O2

795682
type: SpeciesReference
stoichiometry: 1.0
species: 749478

749478
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Diphosphate_HO7P2

795634
type: SpeciesReference
stoichiometry: 1.0
species: 734091

734091
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Coenzyme A_C21H32N7O16P3S

795646
type: SpeciesReference
stoichiometry: 1.0
species: 732465

795658
type: SpeciesReference
stoichiometry: 1.0
species: 731803

751687
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Succinyl-CoA_C25H35N7O19P3S

039695
type: Reaction
name: D-sorbitol dehydrogenase (D-fructose producing)
reversible: false
fast: false
notes: R_SBTD_D2 subsystem: Fructose and Mannose Metabolism R_SBTD_D2 equation: [c] : nad + sbt-D --> fru + h + nadh
is: http://identifiers.org/ec-code/1.1.1.14
product: 840135
is: ENSCAFG00000013672.2
reactant: 840099
product: 840123
product: 840111
reactant: 840087

840135
type: SpeciesReference
stoichiometry: 1.0
species: 747050

840099
type: SpeciesReference
stoichiometry: 1.0
species: 750902

750902
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Sorbitol_C6H14O6

840123
type: SpeciesReference
stoichiometry: 1.0
species: 741259

840111
type: SpeciesReference
stoichiometry: 1.0
species: 738474

840087
type: SpeciesReference
stoichiometry: 1.0
species: 746978

038876
type: Reaction
name: phosphogluconate dehydrogenase
product: 832232
is: ENSCAFG00000016797.2
is: http://identifiers.org/ec-code/1.1.1.44
reversible: false
reactant: 832208
fast: false
reactant: 832220
product: 832256
notes: R_GND subsystem: Pentose Phosphate Pathway R_GND equation: [c] : 6pgc + nadp --> co2 + nadph + ru5p-D
product: 832244

832232
type: SpeciesReference
stoichiometry: 1.0
species: 750695

832208
type: SpeciesReference
stoichiometry: 1.0
species: 747099

832220
type: SpeciesReference
stoichiometry: 1.0
species: 728982

728982
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _6-Phospho-D-gluconate_C6H10O10P

832256
type: SpeciesReference
stoichiometry: 1.0
species: 747173

832244
type: SpeciesReference
stoichiometry: 1.0
species: 733981

037435
type: Reaction
reactant: 818425
product: 818449
reactant: 818413
fast: false
is: ENSCAFG00000015681.2
reactant: 818401
notes: R_UDPGALtg subsystem: Transport, Golgi Apparatus R_UDPGALtg equation: udpgal[c] + ump[g] <==> udpgal[g] + ump[c] R_UGALNACtg subsystem: Transport, Golgi Apparatus R_UGALNACtg equation: udpacgal[c] + ump[g] <==> udpacgal[g] + ump[c]
product: 818437
reversible: true
product: 818461

818425
type: SpeciesReference
stoichiometry: 1.0
species: 753218

753218
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053

818449
type: SpeciesReference
stoichiometry: 1.0
species: 753230

753230
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089

818413
type: SpeciesReference
stoichiometry: 2.0
species: 753423

818401
type: SpeciesReference
stoichiometry: 1.0
species: 753302

753302
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: UDPgalactose_C15H22N2O17P2

818437
type: SpeciesReference
stoichiometry: 2.0
species: 753399

818461
type: SpeciesReference
stoichiometry: 1.0
species: 753314

753314
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: UDPgalactose_C15H22N2O17P2

741995
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 10_C55H80N3O70S8

727214
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: _3',5'-Cyclic GMP_C10H11N5O7P

033706
type: Reaction
reversible: false
reactant: 783415
product: 783451
is: ENSCAFG00000024261.1
reactant: 783403
is: http://identifiers.org/ec-code/2.8.2.23
is: ENSCAFG00000017903.2
notes: R_S3T3g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T3g equation: [g] : hs_pre15 + paps --> h + hspg + pap
name: heparin-glucosamine 3-O-sulfotransferase
fast: false
product: 783439
product: 783427

783415
type: SpeciesReference
stoichiometry: 1.0
species: 748687

783451
type: SpeciesReference
stoichiometry: 1.0
species: 748663

783403
type: SpeciesReference
stoichiometry: 1.0
species: 742369

742369
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 15_C79H114N5O98S11X

783439
type: SpeciesReference
stoichiometry: 1.0
species: 742491

742491
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate proteoglycan_C79H113N5O101S12X

783427
type: SpeciesReference
stoichiometry: 1.0
species: 741283

731417
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _2-Oxoglutarate_C5H4O5

727881
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate_C10H8NO5

748242
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Orotidine 5'-phosphate_C10H10N2O11P

039068
type: Reaction
product: 833952
reactant: 833916
fast: false
notes: R_FRUt1r subsystem: Transport, Extracellular R_FRUt1r equation: fru[e] <==> fru[c] R_GLCt1r subsystem: Transport, Extracellular R_GLCt1r equation: glc-D[e] <==> glc-D[c]
reversible: true
product: 833940
reactant: 833928
is: ENSCAFG00000014082.2

833952
type: SpeciesReference
stoichiometry: 1.0
species: 739815

833916
type: SpeciesReference
stoichiometry: 1.0
species: 739827

833940
type: SpeciesReference
stoichiometry: 1.0
species: 738474

833928
type: SpeciesReference
stoichiometry: 1.0
species: 738486

738546
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Fucose 1-phosphate_C6H11O8P

729477
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: R group 1 Coenzyme A homo sapiens_XCO2C21H31N7O15P3S

032955
type: Reaction
reactant: 777458
reactant: 777421
reversible: true
product: 777495
fast: false
reactant: 777409
notes: R_D_DASH_LACt2 subsystem: Transport, Extracellular R_D_DASH_LACt2 equation: h[e] + lac-D[e] <==> h[c] + lac-D[c] R_L_DASH_LACt2r subsystem: Transport, Extracellular R_L_DASH_LACt2r equation: h[e] + lac-L[e] <==> h[c] + lac-L[c] R_PYRt2r subsystem: Transport, Extracellular R_PYRt2r equation: h[e] + pyr[e] <==> h[c] + pyr[c] R_ACETONEt2 subsystem: Transport, Extracellular R_ACETONEt2 equation: acetone[e] + h[e] <==> acetone[c] + h[c] R_2HBt2 subsystem: Transport, Extracellular R_2HBt2 equation: _2hb[e] + h[e] <==> 2hb[c] + h[c]
reactant: 777445
reactant: 777397
product: 777482
product: 777531
product: 777519
product: 777507
product: 777470
is: ENSCAFG00000006054.2
reactant: 777433

777458
type: SpeciesReference
stoichiometry: 1.0
species: 750381

750381
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Pyruvate_C3H3O3

777421
type: SpeciesReference
stoichiometry: 1.0
species: 744650

744650
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Lactate_C3H5O3

777495
type: SpeciesReference
stoichiometry: 1.0
species: 750369

750369
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Pyruvate_C3H3O3

777409
type: SpeciesReference
stoichiometry: 5.0
species: 741271

777445
type: SpeciesReference
stoichiometry: 1.0
species: 726924

726924
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _2-Hydroxybutyrate_C4H7O3

777397
type: SpeciesReference
stoichiometry: 1.0
species: 730221

730221
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Acetone_C3H6O

777482
type: SpeciesReference
stoichiometry: 1.0
species: 730209

730209
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Acetone_C3H6O

777531
type: SpeciesReference
stoichiometry: 5.0
species: 741259

777519
type: SpeciesReference
stoichiometry: 1.0
species: 744598

744598
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Lactate_C3H5O3

777507
type: SpeciesReference
stoichiometry: 1.0
species: 744637

744637
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Lactate_C3H5O3

777470
type: SpeciesReference
stoichiometry: 1.0
species: 726912

726912
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2-Hydroxybutyrate_C4H7O3

777433
type: SpeciesReference
stoichiometry: 1.0
species: 744611

744611
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: D-Lactate_C3H5O3

737606
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Elaidic carnitine_C25H47NO4

039803
type: Reaction
fast: false
is: ENSCAFG00000024323.1
is: ENSCAFG00000007081.2
is: ENSCAFG00000011634.1
is: ENSCAFG00000000734.2
is: ENSCAFG00000012453.2
is: ENSCAFG00000001401.2
is: ENSCAFG00000003395.2
is: ENSCAFG00000004552.2
is: ENSCAFG00000017823.2
is: ENSCAFG00000023339.1
is: ENSCAFG00000023331.1
is: ENSCAFG00000020173.2
name: glyceraldehyde-3-phosphate dehydrogenase
is: ENSCAFG00000012341.2
is: ENSCAFG00000015077.2
product: 841317
reactant: 841269
is: ENSCAFG00000023617.1
is: ENSCAFG00000008179.2
product: 841329
is: ENSCAFG00000000489.2
notes: R_GAPD subsystem: Glycolysis/Gluconeogenesis R_GAPD equation: [c] : g3p + nad + pi <==> 13dpg + h + nadh
is: ENSCAFG00000006986.2
is: ENSCAFG00000001135.2
is: ENSCAFG00000013374.2
is: http://identifiers.org/ec-code/1.2.1.12
is: ENSCAFG00000007185.2
is: ENSCAFG00000007743.2
is: ENSCAFG00000010472.2
is: ENSCAFG00000007639.2
is: ENSCAFG00000002182.2
is: ENSCAFG00000010618.1
product: 841305
is: ENSCAFG00000014037.2
is: ENSCAFG00000020229.1
reactant: 841281
is: ENSCAFG00000017475.2
reactant: 841293
reversible: true
is: ENSCAFG00000020145.2
is: ENSCAFG00000002325.2
is: ENSCAFG00000010116.2

841317
type: SpeciesReference
stoichiometry: 1.0
species: 741259

841269
type: SpeciesReference
stoichiometry: 1.0
species: 749200

841329
type: SpeciesReference
stoichiometry: 1.0
species: 747050

841305
type: SpeciesReference
stoichiometry: 1.0
species: 726500

726500
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Phospho-D-glyceroyl phosphate_C3H4O10P2

841281
type: SpeciesReference
stoichiometry: 1.0
species: 746978

841293
type: SpeciesReference
stoichiometry: 1.0
species: 739003

739003
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Glyceraldehyde 3-phosphate_C3H5O6P

033306
type: Reaction
reactant: 779916
product: 779953
product: 779941
is: ENSCAFG00000010640.2
reversible: true
fast: false
reactant: 779928
notes: R_GALt1r subsystem: Transport, Extracellular R_GALt1r equation: gal[e] <==> gal[c] R_GLCt1r subsystem: Transport, Extracellular R_GLCt1r equation: glc-D[e] <==> glc-D[c]

779916
type: SpeciesReference
stoichiometry: 1.0
species: 739135

739135
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: D-Galactose_C6H12O6

779953
type: SpeciesReference
stoichiometry: 1.0
species: 739815

779941
type: SpeciesReference
stoichiometry: 1.0
species: 739123

739123
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Galactose_C6H12O6

779928
type: SpeciesReference
stoichiometry: 1.0
species: 739827

033173
type: Reaction
product: 778976
is: ENSCAFG00000005354.2
reactant: 778940
product: 778964
fast: false
name: Ferrochelatase, mitochondrial
reactant: 778952
notes: R_FCLTm subsystem: Heme Biosynthesis R_FCLTm equation: [m] : fe2 + ppp9 --> (2) h + pheme
reversible: false
is: http://identifiers.org/ec-code/4.99.1.1

778976
type: SpeciesReference
stoichiometry: 2.0
species: 741308

778940
type: SpeciesReference
stoichiometry: 1.0
species: 749574

749574
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Protoporphyrin_C34H32N4O4

778964
type: SpeciesReference
stoichiometry: 1.0
species: 749091

749091
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Protoheme_C34H30FeN4O4

778952
type: SpeciesReference
stoichiometry: 1.0
species: 738207

738207
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Fe2+_Fe

032919
type: Reaction
fast: false
is: ENSCAFG00000017222.2
name: serine C-palmitoyltransferase
is: http://identifiers.org/ec-code/2.3.1.50
product: 777288
product: 777264
notes: R_SERPT subsystem: Sphingolipid Metabolism R_SERPT equation: [c] : h + pmtcoa + ser-L --> 3dsphgn + co2 + coa
is: ENSCAFG00000002160.1
reactant: 777252
reversible: false
reactant: 777228
product: 777276
reactant: 777240

777288
type: SpeciesReference
stoichiometry: 1.0
species: 727323

727323
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Dehydrosphinganine_C18H38NO2

777264
type: SpeciesReference
stoichiometry: 1.0
species: 734054

777252
type: SpeciesReference
stoichiometry: 1.0
species: 741259

777228
type: SpeciesReference
stoichiometry: 1.0
species: 751082

751082
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Serine_C3H7NO3

777276
type: SpeciesReference
stoichiometry: 1.0
species: 733981

777240
type: SpeciesReference
stoichiometry: 1.0
species: 749297

749297
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S

736147
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3alpha,7alpha-Dihydroxy-5beta-cholestanate_C27H45O4

739232
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Lc4Cer_C44H79N2O22FULLRCO

732841
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Biotin_C10H15N2O3S

039080
type: Reaction
reactant: 833976
reversible: false
modifier: 834048
product: 834000
fast: false
reactant: 833964
is: http://identifiers.org/ec-code/1.5.1.3
modifier: 834024
is: ENSCAFG00000001201.2
notes: R_DHFR subsystem: Folate Metabolism R_DHFR equation: [c] : dhf + h + nadph <==> nadp + thf R_FOLR2 subsystem: Folate Metabolism R_FOLR2 equation: [c] : fol + nadph --> dhf + nadp
modifier: 834036
product: 833988
modifier: 834060
modifier: 834012

833976
type: SpeciesReference
stoichiometry: 1.0
species: 747173

834000
type: SpeciesReference
stoichiometry: 1.0
species: 747099

833964
type: SpeciesReference
stoichiometry: 1.0
species: 738305

738305
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Folate_C19H18N7O6

736328
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _7,8-Dihydrofolate_C19H19N7O6

833988
type: SpeciesReference
stoichiometry: 1.0
species: 736328

752337
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5,6,7,8-Tetrahydrofolate_C19H21N7O6

742952
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Inosine_C10H12N4O5

750550
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cis-9-retinal_C20H28O

741802
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Hydroxymethylbilane_C40H38N4O17

747136
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

039212
type: Reaction
reactant: 836230
notes: R_UDPXYLtg subsystem: Transport, Golgi Apparatus R_UDPXYLtg equation: udpxyl[c] + ump[g] <==> udpxyl[g] + ump[c] R_UDPGLCtg subsystem: Transport, Golgi Apparatus R_UDPGLCtg equation: udpg[c] + ump[g] <==> udpg[g] + ump[c]
reversible: true
product: 836279
product: 836291
fast: false
reactant: 836242
reactant: 836255
is: ENSCAFG00000001300.2
product: 836267

836230
type: SpeciesReference
stoichiometry: 1.0
species: 753266

836279
type: SpeciesReference
stoichiometry: 2.0
species: 753399

836291
type: SpeciesReference
stoichiometry: 1.0
species: 753278

836242
type: SpeciesReference
stoichiometry: 1.0
species: 753362

753362
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: UDP-D-xylose_C14H20N2O16P2

836255
type: SpeciesReference
stoichiometry: 2.0
species: 753423

836267
type: SpeciesReference
stoichiometry: 1.0
species: 753374

753374
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: UDP-D-xylose_C14H20N2O16P2

740349
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Glycolate_C2H3O3

733762
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cardiolipin (homo sapiens)_C9H16O9P2FULLRCO2FULLR2CO2FULLRCO2FULLR2CO2

040128
type: Reaction
reactant: 843468
product: 843504
notes: R_CLI2tex subsystem: Transport, Extracellular R_CLI2tex equation: cl[e] + (2) i[c] --> cl[c] + (2) i[e] R_CLHCOtex subsystem: Transport, Extracellular R_CLHCOtex equation: cl[e] + (2) hco3[c] --> cl[c] + (2) hco3[e] R_CLFORtex subsystem: Transport, Extracellular R_CLFORtex equation: cl[e] + (2) for[c] --> cl[c] + (2) for[e]
is: ENSCAFG00000003891.2
reactant: 843480
reactant: 843456
product: 843528
reactant: 843444
product: 843492
fast: false
product: 843516
reversible: false

843468
type: SpeciesReference
stoichiometry: 2.0
species: 742588

742588
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Iodide_I

843504
type: SpeciesReference
stoichiometry: 3.0
species: 733738

733738
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Chloride_Cl

843480
type: SpeciesReference
stoichiometry: 3.0
species: 733750

733750
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Chloride_Cl

843456
type: SpeciesReference
stoichiometry: 2.0
species: 738329

738329
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Formate_CH1O2

843528
type: SpeciesReference
stoichiometry: 2.0
species: 741428

741428
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Bicarbonate_CHO3

843444
type: SpeciesReference
stoichiometry: 2.0
species: 741416

741416
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Bicarbonate_CHO3

843492
type: SpeciesReference
stoichiometry: 2.0
species: 738341

738341
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Formate_CH1O2

843516
type: SpeciesReference
stoichiometry: 2.0
species: 742600

742600
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Iodide_I

035588
type: Reaction
is: http://identifiers.org/ec-code/2.4.1.142
product: 801573
notes: R_BDMT_U subsystem: N-Glycan Biosynthesis R_BDMT_U equation: [c] : (0.1) chito2pdol_U + gdpmann --> gdp + h + (0.1) mpdol_U R_BDMT_L subsystem: N-Glycan Biosynthesis R_BDMT_L equation: [c] : (0.1) chito2pdol_L + gdpmann --> gdp + h + (0.1) mpdol_L
reactant: 801548
fast: false
product: 801612
is: ENSCAFG00000019111.2
reactant: 801560
product: 801586
reversible: false
reactant: 801536
product: 801599

801573
type: SpeciesReference
stoichiometry: 2.0
species: 739656

739656
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: GDP_C10H12N5O11P2

801548
type: SpeciesReference
stoichiometry: 2.0
species: 739754

739754
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: GDP-D-mannose_C16H23N5O16P2

801612
type: SpeciesReference
stoichiometry: 2.0
species: 741259

801560
type: SpeciesReference
stoichiometry: 1.0
species: 733299

733299
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N,N'-Diacetylchitobiosyldiphosphodolichol, human liver homolog_C1240H2028N20O170P20

801586
type: SpeciesReference
stoichiometry: 1.0
species: 746713

746713
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol, human liver homolog_C1300H2128N20O220P20

801536
type: SpeciesReference
stoichiometry: 1.0
species: 733311

733311
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N,N'-Diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1185H1940N20O170P20

801599
type: SpeciesReference
stoichiometry: 1.0
species: 746726

746726
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol, human uterine homolog_C1245H2040N20O220P20

730741
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N2-Acetyl-L-ornithine_C7H14N2O3

750890
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Sarcosine_C3H7NO2

747221
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

038585
type: Reaction
product: 830169
reactant: 830108
product: 830132
reactant: 830120
reactant: 830096
notes: R_NTPP11 subsystem: Nucleotides R_NTPP11 equation: [c] : h2o + xtp --> h + ppi + xmp R_NTPP10 subsystem: Nucleotides R_NTPP10 equation: [c] : ditp + h2o --> dimp + h + ppi R_NTPP9 subsystem: Nucleotides R_NTPP9 equation: [c] : h2o + itp --> h + imp + ppi
is: http://identifiers.org/ec-code/3.6.1.19
product: 830156
is: ENSCAFG00000006394.2
fast: false
product: 830181
reactant: 830083
product: 830144
reversible: false

830169
type: SpeciesReference
stoichiometry: 3.0
species: 741259

830108
type: SpeciesReference
stoichiometry: 3.0
species: 741151

830132
type: SpeciesReference
stoichiometry: 1.0
species: 753894

830120
type: SpeciesReference
stoichiometry: 1.0
species: 743024

743024
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: ITP_C10H11N4O14P3

830096
type: SpeciesReference
stoichiometry: 1.0
species: 736535

736535
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dITP_C10H11N4O13P3

830156
type: SpeciesReference
stoichiometry: 1.0
species: 742843

830181
type: SpeciesReference
stoichiometry: 3.0
species: 749466

749466
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Diphosphate_HO7P2

830083
type: SpeciesReference
stoichiometry: 1.0
species: 754220

754220
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: XTP_C10H11N4O15P3

830144
type: SpeciesReference
stoichiometry: 1.0
species: 736499

736499
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dIMP_C10H11N4O7P

738087
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

753918
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _25-Hydroxycholesterol_C27H46O2

036325
type: Reaction
reactant: 808325
notes: R_TRPO2 subsystem: Tryptophan metabolism R_TRPO2 equation: [c] : o2 + trp-L --> Lfmkynr
name: L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing)
is: ENSCAFG00000008591.2
fast: false
reactant: 808313
product: 808337
is: http://identifiers.org/ec-code/1.13.11.11
reversible: false

808325
type: SpeciesReference
stoichiometry: 1.0
species: 747698

747698
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: O2_O2

808313
type: SpeciesReference
stoichiometry: 1.0
species: 752829

752829
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Tryptophan_C11H12N2O2

808337
type: SpeciesReference
stoichiometry: 1.0
species: 729355

729355
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Formylkynurenine_C11H12N2O4

030873
type: Reaction
notes: R_PIt7ir subsystem: Transport, Extracellular R_PIt7ir equation: (3) na1[e] + pi[e] --> (3) na1[c] + pi[c]
reactant: 758399
is: ENSCAFG00000010583.2
fast: false
reactant: 758411
is: ENSCAFG00000010641.2
is: ENSCAFG00000010606.2
is: ENSCAFG00000024892.1
product: 758424
is: ENSCAFG00000011669.2
reversible: false
name: phosphate transport in/out via three Na+ symporter (irreversible)
product: 758436

758399
type: SpeciesReference
stoichiometry: 1.0
species: 749213

758411
type: SpeciesReference
stoichiometry: 3.0
species: 746930

758424
type: SpeciesReference
stoichiometry: 1.0
species: 749200

758436
type: SpeciesReference
stoichiometry: 3.0
species: 746918

737338
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Deoxyuridine_C9H12N2O5

726680
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _1-Pyrroline-5-carboxylate_C5H6NO2

733069
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Carnosine_C9H14N4O3

737067
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: disialyl-T antigen_C36H56N3O26X

036495
type: Reaction
fast: false
name: Fucokinase
is: ENSCAFG00000020144.2
product: 809422
notes: R_FK subsystem: Fructose and Mannose Metabolism R_FK equation: [c] : atp + fuc-L --> adp + fuc1p-L + h
product: 809434
reactant: 809398
product: 809410
reversible: false
is: http://identifiers.org/ec-code/2.7.1.52
reactant: 809386

809422
type: SpeciesReference
stoichiometry: 1.0
species: 730922

730922
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: ADP_C10H12N5O10P2

809434
type: SpeciesReference
stoichiometry: 1.0
species: 741259

809398
type: SpeciesReference
stoichiometry: 1.0
species: 738558

738558
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Fucose_C6H12O5

809410
type: SpeciesReference
stoichiometry: 1.0
species: 738546

809386
type: SpeciesReference
stoichiometry: 1.0
species: 732441

731176
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Adrenaline_C9H14NO3

032474
type: Reaction
name: phospholipase A2
notes: R_PLA2_2 subsystem: Glycerophospholipid Metabolism R_PLA2_2 equation: [c] : h2o + pchol_hs --> Rtotal2 + h + lpchol_hs
product: 773219
reactant: 773171
is: ENSCAFG00000001424.2
product: 773207
reversible: false
product: 773195
fast: false
is: http://identifiers.org/ec-code/3.1.1.4
reactant: 773183

773219
type: SpeciesReference
stoichiometry: 1.0
species: 741259

773171
type: SpeciesReference
stoichiometry: 1.0
species: 748699

748699
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

773207
type: SpeciesReference
stoichiometry: 1.0
species: 729513

729513
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: R total 2 position_CO2FULLR2

773195
type: SpeciesReference
stoichiometry: 1.0
species: 745339

745339
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: lysophosphatidylcholine (homo sapiens)_C8H19NO5PFULLRCO2

773183
type: SpeciesReference
stoichiometry: 1.0
species: 741151

748290
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Oxalate_C2O4

035732
type: Reaction
product: 802530
reactant: 802518
notes: R_DCIm subsystem: Fatty Acid Metabolism R_DCIm equation: [m] : dd2coa <==> dd3coa
is: ENSCAFG00000019399.2
is: http://identifiers.org/ec-code/5.3.3.8
fast: false
reversible: true
name: dodecenoyl-Coenzyme A delta isomerase

802530
type: SpeciesReference
stoichiometry: 1.0
species: 735793

735793
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3-dodecenoyl CoA_C33H52N7O17P3S

802518
type: SpeciesReference
stoichiometry: 1.0
species: 735781

735781
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: trans-Dodec-2-enoyl-CoA_C33H52N7O17P3S

040465
type: Reaction
name: phosphatidylinositol synthase (Homo sapiens)
product: 847341
reactant: 847293
is: http://identifiers.org/ec-code/2.7.8.11
reactant: 847305
product: 847317
product: 847329
reversible: true
is: ENSCAFG00000016979.2
fast: false
notes: R_CDIPTr subsystem: Glycerophospholipid Metabolism R_CDIPTr equation: [c] : cdpdag_hs + inost <==> cmp + h + pail_hs

847341
type: SpeciesReference
stoichiometry: 1.0
species: 741259

847293
type: SpeciesReference
stoichiometry: 1.0
species: 742892

742892
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: myo-Inositol_C6H12O6

847305
type: SpeciesReference
stoichiometry: 1.0
species: 733238

733238
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: CDP diacylglycerol (homo sapiens)_C12H17N3O11P2FULLRCO2FULLR2CO2

847317
type: SpeciesReference
stoichiometry: 1.0
species: 733859

733859
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: CMP_C9H12N3O8P

847329
type: SpeciesReference
stoichiometry: 1.0
species: 748591

748591
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphatidylinositol (homo sapiens)_C9H16O9PFULLRCO2FULLR2CO2

041057
type: Reaction
reversible: false
product: 854086
is: ENSCAFG00000011824.2
product: 854110
product: 854098
reactant: 854062
name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
reactant: 854074
fast: false
notes: R_B3GNT51g subsystem: Blood Group Biosynthesis R_B3GNT51g equation: [g] : galgluside_hs + uacgam --> acglcgalgluside_hs + h + udp

854086
type: SpeciesReference
stoichiometry: 1.0
species: 730500

730500
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)1 (Glc)1 (GlcNAc)1 (Cer)1_C38H69N2O17FULLRCO

854110
type: SpeciesReference
stoichiometry: 1.0
species: 741283

854098
type: SpeciesReference
stoichiometry: 1.0
species: 753157

753157
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: UDP_C9H11N2O12P2

854062
type: SpeciesReference
stoichiometry: 1.0
species: 753121

854074
type: SpeciesReference
stoichiometry: 1.0
species: 739341

739341
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: galactosyl glucosyl ceramide_C30H56NO12FULLRCO

746798
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: n2m2nmasn (w/o peptide linkage)_C58H97N5O41

039322
type: Reaction
modifier: 837158
reactant: 836930
modifier: 837195
product: 837098
reactant: 836990
product: 837038
notes: R_FAS180COA subsystem: Fatty acid elongation R_FAS180COA equation: [c] : (3) h + malcoa + (2) nadph + pmtcoa --> co2 + coa + h2o + (2) nadp + stcoa R_FAS140COA subsystem: Fatty acid elongation R_FAS140COA equation: [c] : ddcacoa + (3) h + malcoa + (2) nadph --> co2 + coa + h2o + (2) nadp + tdcoa R_FAS160COA subsystem: Fatty acid elongation R_FAS160COA equation: [c] : (3) h + malcoa + (2) nadph + tdcoa --> co2 + coa + h2o + (2) nadp + pmtcoa R_FAS100COA subsystem: Fatty acid elongation R_FAS100COA equation: [c] : (3) h + malcoa + (2) nadph + occoa --> co2 + coa + dcacoa + h2o + (2) nadp R_KAS8 subsystem: Fatty acid elongation R_KAS8 equation: [c] : accoa + (20) h + (7) malcoa + (14) nadph --> (7) co2 + (8) coa + (6) h2o + hdca + (14) nadp R_MCOATA subsystem: Fatty Acid Metabolism R_MCOATA equation: [c] : ACP + malcoa <==> coa + malACP R_FAS120COA subsystem: Fatty acid elongation R_FAS120COA equation: [c] : dcacoa + (3) h + malcoa + (2) nadph --> co2 + coa + ddcacoa + h2o + (2) nadp R_ACOATA subsystem: Fatty Acid Metabolism R_ACOATA equation: [c] : ACP + accoa <==> acACP + coa R_FAS80COA_L subsystem: Fatty acid elongation R_FAS80COA_L equation: [c] : accoa + (9) h + (3) malcoa + (6) nadph --> (3) co2 + (3) coa + (3) h2o + (6) nadp + occoa
modifier: 837146
reactant: 837002
product: 837026
product: 837014
reactant: 836954
fast: false
product: 837086
is: http://identifiers.org/ec-code/2.3.1.38
modifier: 837183
product: 837134
reactant: 836918
product: 837122
product: 837074
product: 837110
product: 837062
product: 837050
is: ENSCAFG00000006006.2
reactant: 836942
is: http://identifiers.org/ec-code/2.3.1.86
is: http://identifiers.org/ec-code/2.3.1.41
reversible: false
reactant: 836966
modifier: 837170
reactant: 836978
is: http://identifiers.org/ec-code/2.3.1.39
reactant: 836906
modifier: 837207

836930
type: SpeciesReference
stoichiometry: 15.0
species: 745928

745928
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Malonyl-CoA_C24H33N7O19P3S

837098
type: SpeciesReference
stoichiometry: 30.0
species: 747099

836990
type: SpeciesReference
stoichiometry: 44.0
species: 741259

837038
type: SpeciesReference
stoichiometry: 16.0
species: 734054

729967
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Acetyl-ACP_C13H23N2O8PRS

837002
type: SpeciesReference
stoichiometry: 30.0
species: 747173

837026
type: SpeciesReference
stoichiometry: 1.0
species: 735829

735829
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dodecanoyl-CoA (n-C12:0CoA)_C33H54N7O17P3S

837014
type: SpeciesReference
stoichiometry: 1.0
species: 741476

741476
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Hexadecanoate (n-C16:0)_C16H31O2

836954
type: SpeciesReference
stoichiometry: 1.0
species: 749297

837086
type: SpeciesReference
stoichiometry: 1.0
species: 751470

751470
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S

729210
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: acyl carrier protein_C11H21N2O7PRS

837134
type: SpeciesReference
stoichiometry: 14.0
species: 741151

836918
type: SpeciesReference
stoichiometry: 1.0
species: 751917

751917
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Tetradecanoyl-CoA (n-C14:0CoA)_C35H58N7O17P3S

837122
type: SpeciesReference
stoichiometry: 15.0
species: 733981

837074
type: SpeciesReference
stoichiometry: 1.0
species: 749297

837110
type: SpeciesReference
stoichiometry: 1.0
species: 747914

747914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Octanoyl-CoA (n-C8:0CoA)_C29H46N7O17P3S

837062
type: SpeciesReference
stoichiometry: 1.0
species: 735517

735517
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Decanoyl-CoA (n-C10:0CoA)_C31H50N7O17P3S

837050
type: SpeciesReference
stoichiometry: 1.0
species: 751917

836942
type: SpeciesReference
stoichiometry: 1.0
species: 735517

836966
type: SpeciesReference
stoichiometry: 1.0
species: 747914

836978
type: SpeciesReference
stoichiometry: 2.0
species: 730124

836906
type: SpeciesReference
stoichiometry: 1.0
species: 735829

742684
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Iduronate_C6H9O7

736219
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137

727275
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: _3'-AMP_C10H12N5O7P

031065
type: Reaction
modifier: 760322
reactant: 760138
modifier: 760248
is: ENSCAFG00000004928.2
is: ENSCAFG00000009239.2
modifier: 760285
is: ENSCAFG00000002071.2
product: 760236
product: 760211
reactant: 760175
reactant: 760151
reactant: 760126
modifier: 760260
is: ENSCAFG00000012195.2
modifier: 760309
notes: R_LDH_L subsystem: Glycolysis/Gluconeogenesis R_LDH_L equation: [c] : lac-L + nad <==> h + nadh + pyr R_MCLOR subsystem: Cysteine Metabolism R_MCLOR equation: [c] : mercplac + nad <==> h + mercppyr + nadh R_HPYRR2x subsystem: Glyoxylate and Dicarboxylate Metabolism R_HPYRR2x equation: [c] : h + hpyr + nadh --> glyc-S + nad R_2HBO subsystem: Propanoate Metabolism R_2HBO equation: [c] : 2hb + nad <==> 2obut + h + nadh R_GLXO1 subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO1 equation: [c] : glx + h2o + nad --> (2) h + nadh + oxa
is: http://identifiers.org/ec-code/1.1.1.27
reactant: 760163
modifier: 760297
modifier: 760334
product: 760187
reactant: 760114
fast: false
reversible: false
modifier: 760273
product: 760199
is: http://identifiers.org/ec-code/1.2.3.5
is: ENSCAFG00000006066.2
product: 760224
modifier: 760346

746243
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Mercaptopyruvate_C3H3O3S

760138
type: SpeciesReference
stoichiometry: 1.0
species: 741151

746231
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Mercaptolactate_C3H5O3S

760236
type: SpeciesReference
stoichiometry: 1.0
species: 747050

760211
type: SpeciesReference
stoichiometry: 1.0
species: 740301

740301
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (S)-Glycerate_C3H5O4

760175
type: SpeciesReference
stoichiometry: 1.0
species: 747050

760151
type: SpeciesReference
stoichiometry: 1.0
species: 740132

740132
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Glyoxylate_C2H1O3

760126
type: SpeciesReference
stoichiometry: 1.0
species: 741971

741971
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Hydroxypyruvate_C3H3O4

760163
type: SpeciesReference
stoichiometry: 1.0
species: 741259

727009
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2-Oxobutanoate_C4H5O3

760187
type: SpeciesReference
stoichiometry: 1.0
species: 748266

748266
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Oxalate_C2O4

760114
type: SpeciesReference
stoichiometry: 1.0
species: 746978

760199
type: SpeciesReference
stoichiometry: 1.0
species: 746978

760224
type: SpeciesReference
stoichiometry: 2.0
species: 741259

036095
type: Reaction
reactant: 806569
reversible: true
is: ENSCAFG00000009395.2
product: 806605
is: ENSCAFG00000010574.2
product: 806593
fast: false
reactant: 806581
product: 806617
notes: R_NRPPHRt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_NRPPHRt4_LPAREN_2_RPAREN_r equation: (2) na1[e] + nrpphr[e] <==> (2) na1[c] + nrpphr[c] R_DOPAt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_DOPAt4_LPAREN_2_RPAREN_r equation: dopa[e] + (2) na1[e] <==> dopa[c] + (2) na1[c]
reactant: 806557

806569
type: SpeciesReference
stoichiometry: 4.0
species: 746930

806605
type: SpeciesReference
stoichiometry: 4.0
species: 746918

806593
type: SpeciesReference
stoichiometry: 1.0
species: 747553

806581
type: SpeciesReference
stoichiometry: 1.0
species: 747565

747565
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Norepinephrine_C8H12NO3

806617
type: SpeciesReference
stoichiometry: 1.0
species: 736983

806557
type: SpeciesReference
stoichiometry: 1.0
species: 736995

736995
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Dopamine_C8H12NO2

743697
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 13_C143H231N10O111S3X

727360
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Hydroxyanthranilate_C7H7NO3

726368
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _11-Deoxycorticosterone_C21H30O3

728173
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Imidazolone-5-propanoate_C6H7N2O3

751808
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Taurine_C2H7NO3S

747589
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: nervonic acid_C24H45O2

745182
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Linoleyl carnitine_C25H45NO4

741512
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Hexadecanoate (n-C16:0)_C16H31O2

744585
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)2-Xyl-L-Ser (protein)_C17H29O14X

032907
type: Reaction
reactant: 777108
product: 777216
is: ENSCAFG00000002871.2
is: ENSCAFG00000017122.1
is: http://identifiers.org/ec-code/2.8.2.1
reactant: 777084
fast: false
product: 777144
is: ENSCAFG00000002873.2
product: 777180
product: 777168
reactant: 777132
product: 777156
product: 777192
is: http://identifiers.org/ec-code/2.8.2.4
reactant: 777096
notes: R_DOPASULT subsystem: Tyrosine metabolism R_DOPASULT equation: [c] : dopa + paps --> dopasf + h + pap R_4NPHSULT subsystem: CYP Metabolism R_4NPHSULT equation: [c] : 4nph + paps --> 4nphsf + h + pap R_TRIODTHYSULT subsystem: Tyrosine metabolism R_TRIODTHYSULT equation: [c] : paps + triodthy --> h + pap + triodthysuf R_ESTSULT subsystem: Steroid Metabolism R_ESTSULT equation: [c] : estrone + paps --> estrones + h + pap R_TYMSULT subsystem: Tyrosine metabolism R_TYMSULT equation: [c] : paps + tym --> h + pap + tymsf
reactant: 777072
reversible: false
product: 777204
reactant: 777120

777108
type: SpeciesReference
stoichiometry: 1.0
species: 728269

777216
type: SpeciesReference
stoichiometry: 5.0
species: 741259

777084
type: SpeciesReference
stoichiometry: 5.0
species: 748675

777144
type: SpeciesReference
stoichiometry: 1.0
species: 737846

737846
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Estrone 3-sulfate_C18H21O5S

777180
type: SpeciesReference
stoichiometry: 1.0
species: 728281

777168
type: SpeciesReference
stoichiometry: 1.0
species: 737019

777132
type: SpeciesReference
stoichiometry: 1.0
species: 736983

777156
type: SpeciesReference
stoichiometry: 5.0
species: 748651

777192
type: SpeciesReference
stoichiometry: 1.0
species: 753059

777096
type: SpeciesReference
stoichiometry: 1.0
species: 753047

777072
type: SpeciesReference
stoichiometry: 1.0
species: 737786

737786
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Estrone_C18H22O2

777204
type: SpeciesReference
stoichiometry: 1.0
species: 752816

752816
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Triiodothyronine sulfate_C15H11I3NO7S

777120
type: SpeciesReference
stoichiometry: 1.0
species: 752790

752790
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Triiodothyronine_C15H12I3NO4

032162
type: Reaction
product: 770401
product: 770389
is: http://identifiers.org/ec-code/2.8.2.23
reactant: 770377
product: 770413
is: ENSCAFG00000025345.1
reversible: false
name: heparin-glucosamine 3-O-sulfotransferase
reactant: 770365
fast: false
notes: R_S3T1g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T1g equation: [g] : hs_pre13 + paps --> h + hs_pre14 + pap

770401
type: SpeciesReference
stoichiometry: 1.0
species: 742357

742357
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 14_C79H115N5O95S10X

770389
type: SpeciesReference
stoichiometry: 1.0
species: 741283

770377
type: SpeciesReference
stoichiometry: 1.0
species: 742345

742345
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 13_C79H116N5O92S9X

770413
type: SpeciesReference
stoichiometry: 1.0
species: 748663

770365
type: SpeciesReference
stoichiometry: 1.0
species: 748687

036881
type: Reaction
fast: false
modifier: 812493
modifier: 812457
modifier: 812505
reactant: 812373
reactant: 812361
product: 812397
is: http://identifiers.org/ec-code/1.2.1.49
is: http://identifiers.org/ec-code/1.1.1.78
reactant: 812337
reactant: 812325
product: 812445
product: 812409
product: 812421
product: 812385
notes: R_ALCD22_D subsystem: Pyruvate Metabolism R_ALCD22_D equation: [c] : lald-D + nad --> h + mthgxl + nadh R_ALCD1 subsystem: Miscellaneous R_ALCD1 equation: [c] : meoh + nad <==> fald + h + nadh R_ALCD2if subsystem: Glycolysis/Gluconeogenesis R_ALCD2if equation: [c] : etoh + nad --> acald + h + nadh R_ALCD21_D subsystem: Pyruvate Metabolism R_ALCD21_D equation: [c] : 12ppd-R + nad --> h + lald-D + nadh R_ALCD22_L subsystem: Pyruvate Metabolism R_ALCD22_L equation: [c] : lald-L + nad --> h + mthgxl + nadh R_ALCD21_L subsystem: Pyruvate Metabolism R_ALCD21_L equation: [c] : 12ppd-S + nad --> h + lald-L + nadh
modifier: 812481
modifier: 812469
product: 812433
is: ENSCAFG00000000021.2
reactant: 812349
reversible: false
reactant: 812312
is: http://identifiers.org/ec-code/1.1.1.1

746183
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Methanol_CH4O1

812373
type: SpeciesReference
stoichiometry: 1.0
species: 744676

744676
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Lactaldehyde_C3H6O2

812361
type: SpeciesReference
stoichiometry: 1.0
species: 737943

737943
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Ethanol_C2H6O

812397
type: SpeciesReference
stoichiometry: 1.0
species: 744700

812337
type: SpeciesReference
stoichiometry: 1.0
species: 726428

726428
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (R)-Propane-1,2-diol_C3H8O2

812325
type: SpeciesReference
stoichiometry: 1.0
species: 744700

812445
type: SpeciesReference
stoichiometry: 5.0
species: 747050

812409
type: SpeciesReference
stoichiometry: 1.0
species: 730076

730076
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Acetaldehyde_C2H4O

812421
type: SpeciesReference
stoichiometry: 1.0
species: 744676

812385
type: SpeciesReference
stoichiometry: 2.0
species: 746750

746750
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Methylglyoxal_C3H4O2

738123
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Formaldehyde_CH2O

812433
type: SpeciesReference
stoichiometry: 5.0
species: 741259

812349
type: SpeciesReference
stoichiometry: 5.0
species: 746978

812312
type: SpeciesReference
stoichiometry: 1.0
species: 726440

726440
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (S)-Propane-1,2-diol_C3H8O2

750478
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: alpha-D-Ribose 1-phosphate_C5H9O8P

733213
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: CDP_C9H12N3O11P2

747674
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Trimethyl-2-aminoethylphosphonate_C5H13NO3P

W3 CDTF: Fri Feb 03 12:51:56 GMT 2012

749586
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Protoporphyrinogen IX_C34H38N4O4

727239
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3,5-Diiodo-L-tyrosine_C9H9I2NO3

034432
type: Reaction
product: 789747
reactant: 789735
notes: R_H2Otm subsystem: Transport, Mitochondrial R_H2Otm equation: h2o[c] <==> h2o[m]
is: ENSCAFG00000017480.2
fast: false
reversible: true
name: H2O transport, mitochondrial

789747
type: SpeciesReference
stoichiometry: 1.0
species: 741199

789735
type: SpeciesReference
stoichiometry: 1.0
species: 741151

730112
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Acetaldehyde_C2H4O

734030
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: CO2_CO2

745916
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Malate_C4H4O5

034793
type: Reaction
product: 793258
is: http://identifiers.org/ec-code/3.2.1.113
reactant: 793162
reactant: 793138
reactant: 793054
is: ENSCAFG00000012769.2
product: 793318
product: 793294
reactant: 793114
product: 793210
fast: false
reactant: 793126
product: 793234
reactant: 793090
is: ENSCAFG00000019511.2
product: 793270
product: 793198
notes: R_MM5bg subsystem: N-Glycan Biosynthesis R_MM5bg equation: [g] : h2o + m5masnB1 --> m4masn + man R_MM7Cbg subsystem: N-Glycan Biosynthesis R_MM7Cbg equation: [g] : h2o + m7masnC --> m6masnC + man R_MM6B2g subsystem: N-Glycan Biosynthesis R_MM6B2g equation: [g] : h2o + m6masnB2 --> m5masnB2 + man R_MM6bg subsystem: N-Glycan Biosynthesis R_MM6bg equation: [g] : h2o + m6masnC --> m5masnC + man R_MM8Ag subsystem: N-Glycan Biosynthesis R_MM8Ag equation: [g] : h2o + m8masn --> m7masnA + man R_MM6ag subsystem: N-Glycan Biosynthesis R_MM6ag equation: [g] : h2o + m6masnA --> m5masnC + man R_MM8Cg subsystem: N-Glycan Biosynthesis R_MM8Cg equation: [g] : h2o + m8masn --> m7masnC + man R_MM7Cag subsystem: N-Glycan Biosynthesis R_MM7Cag equation: [g] : h2o + m7masnA --> m6masnC + man R_MM6B1ag subsystem: N-Glycan Biosynthesis R_MM6B1ag equation: [g] : h2o + m6masnB1 --> m5masnB1 + man R_MM7Ag subsystem: N-Glycan Biosynthesis R_MM7Ag equation: [g] : h2o + m7masnA --> m6masnA + man R_MM7B2g subsystem: N-Glycan Biosynthesis R_MM7B2g equation: [g] : h2o + m7masnB --> m6masnB2 + man R_MM6B1bg subsystem: N-Glycan Biosynthesis R_MM6B1bg equation: [g] : h2o + m6masnB2 --> m5masnB1 + man R_MM5ag subsystem: N-Glycan Biosynthesis R_MM5ag equation: [g] : h2o + m5masnC --> m4masn + man R_MM5cg subsystem: N-Glycan Biosynthesis R_MM5cg equation: [g] : h2o + m5masnB2 --> m4masn + man R_MM7B1g subsystem: N-Glycan Biosynthesis R_MM7B1g equation: [g] : h2o + m7masnB --> m6masnB1 + man
product: 793246
reactant: 793066
reactant: 793102
reactant: 793186
reversible: false
product: 793222
product: 793306
product: 793282
reactant: 793078
reactant: 793174
reactant: 793150

793258
type: SpeciesReference
stoichiometry: 2.0
species: 745675

745675
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X

793162
type: SpeciesReference
stoichiometry: 2.0
species: 745784

745784
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C70H117N2O55X

793138
type: SpeciesReference
stoichiometry: 2.0
species: 745711

745711
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform A (protein)_C64H107N2O50X

793054
type: SpeciesReference
stoichiometry: 2.0
species: 745723

745723
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein)_C64H107N2O50X

793318
type: SpeciesReference
stoichiometry: 1.0
species: 745639

745639
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X

793294
type: SpeciesReference
stoichiometry: 15.0
species: 746086

746086
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: D-Mannose_C6H12O6

793114
type: SpeciesReference
stoichiometry: 1.0
species: 745651

745651
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X

793210
type: SpeciesReference
stoichiometry: 1.0
species: 745591

745591
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)5-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C52H87N2O40X

793126
type: SpeciesReference
stoichiometry: 1.0
species: 745675

793234
type: SpeciesReference
stoichiometry: 1.0
species: 745747

745747
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform C (protein)_C64H107N2O50X

793090
type: SpeciesReference
stoichiometry: 1.0
species: 745747

793270
type: SpeciesReference
stoichiometry: 1.0
species: 745711

793198
type: SpeciesReference
stoichiometry: 3.0
species: 745543

745543
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C46H77N2O35X

793246
type: SpeciesReference
stoichiometry: 1.0
species: 745651

793066
type: SpeciesReference
stoichiometry: 1.0
species: 745591

793102
type: SpeciesReference
stoichiometry: 15.0
species: 741175

741175
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: H2O_H2O

793186
type: SpeciesReference
stoichiometry: 1.0
species: 745639

793222
type: SpeciesReference
stoichiometry: 2.0
species: 745603

745603
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)5-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C52H87N2O40X

793306
type: SpeciesReference
stoichiometry: 2.0
species: 745579

745579
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)5-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C52H87N2O40X

793282
type: SpeciesReference
stoichiometry: 1.0
species: 745663

745663
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X

793078
type: SpeciesReference
stoichiometry: 1.0
species: 745603

793174
type: SpeciesReference
stoichiometry: 1.0
species: 745579

793150
type: SpeciesReference
stoichiometry: 2.0
species: 745663

730669
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: N-Acetylneuraminate_C11H18NO9

030453
type: Reaction
reactant: 754632
is: http://identifiers.org/ec-code/1.2.1.3
reactant: 754680
product: 754971
reactant: 754656
product: 754826
product: 754983
reactant: 754740
product: 754838
product: 754910
product: 754922
is: http://identifiers.org/ec-code/1.2.1.21
reactant: 754752
is: http://identifiers.org/ec-code/1.2.1.4
product: 754850
reactant: 754668
product: 754862
reactant: 754728
reactant: 754776
is: ENSCAFG00000011246.2
product: 754874
reactant: 754789
reversible: false
reactant: 754644
product: 754934
fast: false
reactant: 754801
reactant: 754692
product: 754946
is: ENSCAFG00000018166.2
product: 754958
reactant: 754704
product: 754886
product: 754813
product: 754898
reactant: 754716
notes: R_5HOXINDACTOX subsystem: Tryptophan metabolism R_5HOXINDACTOX equation: [c] : 5hoxindact + h2o + nad --> 5hoxindoa + (2) h + nadh R_BAMPPALDOX subsystem: beta-Alanine metabolism R_BAMPPALDOX equation: [c] : bamppald + h2o + nad --> ala-B + (2) h + nadh R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_ALDD21 subsystem: Fatty Acid Metabolism R_ALDD21 equation: [c] : h2o + nad + pristanal --> (2) h + nadh + prist R_IMACTD subsystem: Histidine Metabolism R_IMACTD equation: [c] : h2o + im4act + nad --> (2) h + im4ac + nadh R_ALDD2y subsystem: Glycolysis/Gluconeogenesis R_ALDD2y equation: [c] : acald + h2o + nadp --> ac + (2) h + nadph R_ALDD20x subsystem: Tryptophan metabolism R_ALDD20x equation: [c] : h2o + id3acald + nad --> (2) h + ind3ac + nadh R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_PYLALDOX subsystem: Limonene and pinene degradation R_PYLALDOX equation: [c] : h2o + nad + pylald --> (2) h + nadh + peracd R_NABTNO subsystem: Arginine and Proline Metabolism R_NABTNO equation: [c] : h2o + n4abutn + nad --> 4aabutn + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh
reactant: 754764

754632
type: SpeciesReference
stoichiometry: 1.0
species: 750345

750345
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Perillyl aldehyde_C10H14O

754680
type: SpeciesReference
stoichiometry: 1.0
species: 749779

749779
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: pristanal_C19H38O

754971
type: SpeciesReference
stoichiometry: 1.0
species: 744637

754656
type: SpeciesReference
stoichiometry: 1.0
species: 746882

746882
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N4-Acetylaminobutanal_C6H11NO2

754826
type: SpeciesReference
stoichiometry: 2.0
species: 729979

729979
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Acetate_C2H3O2

754983
type: SpeciesReference
stoichiometry: 1.0
species: 747173

754740
type: SpeciesReference
stoichiometry: 1.0
species: 744676

754838
type: SpeciesReference
stoichiometry: 1.0
species: 748959

748959
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Perillic acid_C10H13O2

754910
type: SpeciesReference
stoichiometry: 1.0
species: 742868

742868
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Indole-3-acetate_C10H8NO2

754922
type: SpeciesReference
stoichiometry: 1.0
species: 744598

754752
type: SpeciesReference
stoichiometry: 1.0
species: 742819

742819
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Imidazole-4-acetaldehyde_C5H6N2O

754850
type: SpeciesReference
stoichiometry: 1.0
species: 739877

739877
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Glucarate_C6H8O8

754668
type: SpeciesReference
stoichiometry: 1.0
species: 739486

739486
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Glycolaldehyde_C2H4O2

754862
type: SpeciesReference
stoichiometry: 1.0
species: 740349

754728
type: SpeciesReference
stoichiometry: 1.0
species: 739790

739790
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-glucurono-6,3-lactone_C6H8O6

754776
type: SpeciesReference
stoichiometry: 1.0
species: 747099

754874
type: SpeciesReference
stoichiometry: 1.0
species: 749755

749755
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: pristanic acid_C19H37O2

754789
type: SpeciesReference
stoichiometry: 1.0
species: 742660

742660
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Indole-3-acetaldehyde_C10H9NO

754644
type: SpeciesReference
stoichiometry: 12.0
species: 746978

754934
type: SpeciesReference
stoichiometry: 27.0
species: 741259

754801
type: SpeciesReference
stoichiometry: 1.0
species: 732537

732537
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: beta-Aminopropion aldehyde_C3H8NO

754692
type: SpeciesReference
stoichiometry: 1.0
species: 744700

754946
type: SpeciesReference
stoichiometry: 1.0
species: 727955

727955
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Acetamidobutanoate_C6H10NO3

754958
type: SpeciesReference
stoichiometry: 12.0
species: 747050

754704
type: SpeciesReference
stoichiometry: 14.0
species: 741151

754886
type: SpeciesReference
stoichiometry: 1.0
species: 728692

728692
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Hydroxyindoleacetate_C10H8NO3

754813
type: SpeciesReference
stoichiometry: 1.0
species: 742794

742794
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Imidazole-4-acetate_C5H5N2O2

754898
type: SpeciesReference
stoichiometry: 1.0
species: 731465

754716
type: SpeciesReference
stoichiometry: 2.0
species: 730076

754764
type: SpeciesReference
stoichiometry: 1.0
species: 728668

728668
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Hydroxyindoleacetaldehyde_C10H9NO2

743841
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 24_C191H306N13O158S7X

036422
type: Reaction
reactant: 808962
is: ENSCAFG00000023963.1
reversible: true
reactant: 808974
reactant: 808986
product: 808998
notes: R_CITtbm subsystem: Transport, Mitochondrial R_CITtbm equation: cit[c] + pep[m] <==> cit[m] + pep[c] R_CITtam subsystem: Transport, Mitochondrial R_CITtam equation: cit[c] + mal-L[m] <==> cit[m] + mal-L[c]
product: 809010
product: 809022
fast: false

808962
type: SpeciesReference
stoichiometry: 1.0
species: 748922

748922
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Phosphoenolpyruvate_C3H2O6P

808974
type: SpeciesReference
stoichiometry: 1.0
species: 745916

808986
type: SpeciesReference
stoichiometry: 2.0
species: 733678

808998
type: SpeciesReference
stoichiometry: 2.0
species: 733702

733702
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Citrate_C6H5O7

809010
type: SpeciesReference
stoichiometry: 1.0
species: 748910

748910
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Phosphoenolpyruvate_C3H2O6P

809022
type: SpeciesReference
stoichiometry: 1.0
species: 745904

745904
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Malate_C4H4O5

748146
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: hydroxide ion_HO

750068
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Prostaglandin H2_C20H31O5

039406
type: Reaction
reactant: 837832
is: ENSCAFG00000013439.2
reactant: 837856
fast: false
is: ENSCAFG00000018237.2
is: ENSCAFG00000023850.1
product: 837964
reactant: 837844
is: ENSCAFG00000013498.2
product: 837928
product: 837940
reactant: 837892
product: 837952
reactant: 837868
reactant: 837880
product: 837916
reversible: true
notes: R_H2Ot subsystem: Transport, Extracellular R_H2Ot equation: h2o[e] <==> h2o[c] R_UREAt5 subsystem: Transport, Extracellular R_UREAt5 equation: h2o[e] + urea[e] <==> h2o[c] + urea[c] R_GLCt4_2 subsystem: Transport, Extracellular R_GLCt4_2 equation: glc-D[e] + (2) na1[e] <==> glc-D[c] + (2) na1[c] R_GLCt2_2 subsystem: Transport, Extracellular R_GLCt2_2 equation: glc-D[e] + (2) h[e] <==> glc-D[c] + (2) h[c] R_UREAt subsystem: Transport, Extracellular R_UREAt equation: urea[e] <==> urea[c] R_GALt2_2 subsystem: Transport, Extracellular R_GALt2_2 equation: gal[e] + (2) h[e] <==> gal[c] + (2) h[c] R_GALt4_2 subsystem: Transport, Extracellular R_GALt4_2 equation: gal[e] + (2) na1[e] <==> gal[c] + (2) na1[c] R_NAt subsystem: Transport, Extracellular R_NAt equation: na1[e] <==> na1[c]
product: 837904

837832
type: SpeciesReference
stoichiometry: 2.0
species: 739135

837856
type: SpeciesReference
stoichiometry: 5.0
species: 746930

837964
type: SpeciesReference
stoichiometry: 2.0
species: 753543

753543
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Urea_CH4N2O

837844
type: SpeciesReference
stoichiometry: 4.0
species: 741271

837928
type: SpeciesReference
stoichiometry: 2.0
species: 741151

837940
type: SpeciesReference
stoichiometry: 2.0
species: 739815

837892
type: SpeciesReference
stoichiometry: 2.0
species: 753555

753555
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Urea_CH4N2O

837952
type: SpeciesReference
stoichiometry: 4.0
species: 741259

837868
type: SpeciesReference
stoichiometry: 2.0
species: 739827

837880
type: SpeciesReference
stoichiometry: 2.0
species: 741163

741163
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: H2O_H2O

837916
type: SpeciesReference
stoichiometry: 5.0
species: 746918

837904
type: SpeciesReference
stoichiometry: 2.0
species: 739123

033803
type: Reaction
is: ENSCAFG00000003841.2
product: 783860
reactant: 783836
is: ENSCAFG00000014397.2
is: http://identifiers.org/ec-code/3.2.1.26
reversible: false
reactant: 783824
reactant: 783812
is: http://identifiers.org/ec-code/3.2.1.3
product: 783885
reactant: 783788
notes: R_SUCRe subsystem: Galactose metabolism R_SUCRe equation: [e] : h2o + sucr --> fru + glc-D R_MLTG1e subsystem: Starch and Sucrose Metabolism R_MLTG1e equation: [e] : h2o + malttr --> glc-D + malt R_GAMYe subsystem: Starch and Sucrose Metabolism R_GAMYe equation: [e] : glygn5 + h2o --> Tyr-ggn + malt R_MALTe subsystem: Starch and Sucrose Metabolism R_MALTe equation: [e] : h2o + malt --> (2) glc-D
product: 783848
product: 783873
is: http://identifiers.org/ec-code/3.2.1.20
fast: false
reactant: 783800

783860
type: SpeciesReference
stoichiometry: 2.0
species: 745976

745976
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Maltose_C12H22O11

783836
type: SpeciesReference
stoichiometry: 1.0
species: 746013

746013
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Maltotriose_C18H32O16

783824
type: SpeciesReference
stoichiometry: 1.0
species: 740445

740445
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: glycogen, structure 5 (glycogenin-2[1,4-Glc])_C12H21O11X

783812
type: SpeciesReference
stoichiometry: 4.0
species: 741163

783885
type: SpeciesReference
stoichiometry: 1.0
species: 738486

783788
type: SpeciesReference
stoichiometry: 1.0
species: 751699

751699
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Sucrose_C12H22O11

783848
type: SpeciesReference
stoichiometry: 1.0
species: 729895

729895
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Tyr-194 of apo-glycogenin protein (primer for glycogen synthesis)_XOH

783873
type: SpeciesReference
stoichiometry: 4.0
species: 739827

783800
type: SpeciesReference
stoichiometry: 1.0
species: 745976

039599
type: Reaction
notes: R_GLXO2p subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO2p equation: [x] : glx + h2o + o2 --> h + h2o2 + oxa R_GLYCTO1p subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLYCTO1p equation: [x] : glyclt + o2 --> glx + h2o2
reactant: 839209
reactant: 839233
product: 839281
fast: false
reversible: false
is: ENSCAFG00000005890.2
product: 839269
reactant: 839197
product: 839245
reactant: 839221
product: 839257
is: ENSCAFG00000010027.2

839209
type: SpeciesReference
stoichiometry: 1.0
species: 741235

839233
type: SpeciesReference
stoichiometry: 1.0
species: 740156

740156
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Glyoxylate_C2H1O3

839281
type: SpeciesReference
stoichiometry: 1.0
species: 741344

839269
type: SpeciesReference
stoichiometry: 1.0
species: 748290

839197
type: SpeciesReference
stoichiometry: 1.0
species: 740373

740373
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Glycolate_C2H3O3

839245
type: SpeciesReference
stoichiometry: 2.0
species: 741139

839221
type: SpeciesReference
stoichiometry: 2.0
species: 747758

839257
type: SpeciesReference
stoichiometry: 1.0
species: 740156

030657
type: Reaction
notes: R_LGTHL subsystem: Pyruvate Metabolism R_LGTHL equation: [c] : gthrd + mthgxl --> lgt-S
name: lactoylglutathione lyase
product: 756394
reactant: 756382
is: http://identifiers.org/ec-code/4.4.1.5
fast: false
is: ENSCAFG00000001493.2
reactant: 756370
reversible: false

756394
type: SpeciesReference
stoichiometry: 1.0
species: 745013

745013
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (R)-S-Lactoylglutathione_C13H20N3O8S

756382
type: SpeciesReference
stoichiometry: 1.0
species: 746750

756370
type: SpeciesReference
stoichiometry: 1.0
species: 740922

740922
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Reduced glutathione_C10H16N3O6S

735385
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: dADP_C10H12N5O9P2

033973
type: Reaction
name: Serine/Lysine Na-dependent exchange (Ser in)
notes: R_SERLYSNaex subsystem: Transport, Extracellular R_SERLYSNaex equation: lys-L[c] + na1[e] + ser-L[e] --> lys-L[e] + na1[c] + ser-L[c]
reactant: 785343
is: ENSCAFG00000011177.2
reactant: 785331
reactant: 785355
product: 785379
fast: false
product: 785367
product: 785392
reversible: false

785343
type: SpeciesReference
stoichiometry: 1.0
species: 746930

785331
type: SpeciesReference
stoichiometry: 1.0
species: 745399

745399
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Lysine_C6H15N2O2

785355
type: SpeciesReference
stoichiometry: 1.0
species: 751094

785379
type: SpeciesReference
stoichiometry: 1.0
species: 746918

785367
type: SpeciesReference
stoichiometry: 1.0
species: 751082

785392
type: SpeciesReference
stoichiometry: 1.0
species: 745411

745411
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Lysine_C6H15N2O2

726973
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _2-Methylbutanoyl-CoA_C26H40N7O17P3S

036009
type: Reaction
reversible: false
reactant: 805466
reactant: 805442
is: ENSCAFG00000013729.2
product: 805478
fast: false
product: 805490
reactant: 805454
reactant: 805430
notes: R_CHTNASEe subsystem: Aminosugar Metabolism R_CHTNASEe equation: [e] : chtn + (2) h2o --> (3) acgam R_CHTNASE subsystem: Aminosugar Metabolism R_CHTNASE equation: [c] : chtn + (2) h2o --> (3) acgam
is: http://identifiers.org/ec-code/3.2.1.14

805466
type: SpeciesReference
stoichiometry: 1.0
species: 733666

733666
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: chitin_C24H41N3O16

805442
type: SpeciesReference
stoichiometry: 2.0
species: 741163

805478
type: SpeciesReference
stoichiometry: 3.0
species: 730403

730403
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Acetyl-D-glucosamine_C8H15NO6

805490
type: SpeciesReference
stoichiometry: 3.0
species: 730415

730415
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: N-Acetyl-D-glucosamine_C8H15NO6

805454
type: SpeciesReference
stoichiometry: 2.0
species: 741151

805430
type: SpeciesReference
stoichiometry: 1.0
species: 733654

733654
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: chitin_C24H41N3O16

743975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 34_C241H385N17O202S10X

726512
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _15-Hydroperoxyeicosatetraenoic acid_C20H31O4

732272
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Arginine_C6H15N4O2

750153
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: phosphatidylserine (homo sapiens)_C6H11NO6PFULLRCO2FULLR2CO2

038779
type: Reaction
fast: false
product: 831594
is: ENSCAFG00000008737.2
is: ENSCAFG00000015041.2
product: 831582
is: http://identifiers.org/ec-code/2.4.1.119
is: ENSCAFG00000011134.2
notes: R_DOLASNT_Ler subsystem: N-Glycan Biosynthesis R_DOLASNT_Ler equation: [r] : Asn-X-Ser/Thr + (0.1) g3m8mpdol_L --> (0.1) doldp_L + g3m8masn + h R_DOLASNT_Uer subsystem: N-Glycan Biosynthesis R_DOLASNT_Uer equation: [r] : Asn-X-Ser/Thr + (0.1) g3m8mpdol_U --> (0.1) doldp_U + g3m8masn + h
reactant: 831546
product: 831606
reversible: false
product: 831618
reactant: 831570
reactant: 831558
is: ENSCAFG00000004148.2

831594
type: SpeciesReference
stoichiometry: 2.0
species: 738967

738967
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C88H147N2O70X

831582
type: SpeciesReference
stoichiometry: 1.0
species: 736813

831546
type: SpeciesReference
stoichiometry: 2.0
species: 729246

729246
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: protein-linked asparagine residue (N-glycosylation site)_XH

831606
type: SpeciesReference
stoichiometry: 1.0
species: 736825

831618
type: SpeciesReference
stoichiometry: 2.0
species: 741332

831570
type: SpeciesReference
stoichiometry: 1.0
species: 738979

738979
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1960H3228N20O770P20

831558
type: SpeciesReference
stoichiometry: 1.0
species: 738991

738991
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1905H3140N20O770P20

754233
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Xanthosine_C10H12N4O6

032462
type: Reaction
reversible: false
fast: false
notes: R_ATPtm subsystem: Transport, Mitochondrial R_ATPtm equation: adp[c] + atp[m] --> adp[m] + atp[c]
name: ADP/ATP transporter, mitochondrial
reactant: 773123
reactant: 773135
product: 773159
is: ENSCAFG00000007596.2
is: ENSCAFG00000010987.2
is: ENSCAFG00000018384.2
product: 773147

773123
type: SpeciesReference
stoichiometry: 1.0
species: 730922

773135
type: SpeciesReference
stoichiometry: 1.0
species: 732465

773159
type: SpeciesReference
stoichiometry: 1.0
species: 730946

773147
type: SpeciesReference
stoichiometry: 1.0
species: 732441

736583
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dihomo-gamma-linolenyl coenzyme A_C41H64N7O17P3S

746388
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1D-myo-Inositol 1,3,4,5,6-pentakisphosphate_C6H7O21P5

751856
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: taurocholic acid_C26H45NO7S

748326
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

038379
type: Reaction
reactant: 828508
is: http://identifiers.org/ec-code/1.14.17.1
product: 828532
is: ENSCAFG00000000184.2
reactant: 828496
is: ENSCAFG00000019783.2
fast: false
reactant: 828484
reversible: false
product: 828520
product: 828544
notes: R_DOPABMO subsystem: Tyrosine metabolism R_DOPABMO equation: [c] : ascb-L + dopa + o2 --> dhdascb + h2o + nrpphr
name: dopamine beta-monooxygenase

828508
type: SpeciesReference
stoichiometry: 1.0
species: 732308

732308
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Ascorbate_C6H8O6

828532
type: SpeciesReference
stoichiometry: 1.0
species: 736243

828496
type: SpeciesReference
stoichiometry: 1.0
species: 747698

828484
type: SpeciesReference
stoichiometry: 1.0
species: 736983

828520
type: SpeciesReference
stoichiometry: 1.0
species: 747553

828544
type: SpeciesReference
stoichiometry: 1.0
species: 741151

038791
type: Reaction
reversible: false
product: 831678
name: retinyl ester hydrolase
notes: R_RETH subsystem: Vitamin A Metabolism R_RETH equation: [c] : h2o + retfa --> Rtotal2 + h + retinol
product: 831654
fast: false
reactant: 831642
is: ENSCAFG00000011294.1
reactant: 831630
product: 831666

831678
type: SpeciesReference
stoichiometry: 1.0
species: 741259

831654
type: SpeciesReference
stoichiometry: 1.0
species: 750610

750610
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Retinol_C20H30O

831642
type: SpeciesReference
stoichiometry: 1.0
species: 741151

831630
type: SpeciesReference
stoichiometry: 1.0
species: 750514

750514
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: fatty acid retinol_C20H29OFULLR2CO

831666
type: SpeciesReference
stoichiometry: 1.0
species: 729513

039707
type: Reaction
reactant: 840195
notes: R_LSTO1r subsystem: Cholesterol Metabolism R_LSTO1r equation: [r] : chlstol + h + nadph + o2 --> ddsmsterol + (2) h2o + nadp R_LSTO2r subsystem: Cholesterol Metabolism R_LSTO2r equation: [r] : h + lthstrl + nadph + o2 --> 7dhchsterol + (2) h2o + nadp
reactant: 840171
reactant: 840147
is: ENSCAFG00000011805.1
product: 840231
product: 840207
product: 840243
reactant: 840183
reactant: 840159
is: http://identifiers.org/ec-code/1.3.3.2
reversible: false
fast: false
product: 840219

840195
type: SpeciesReference
stoichiometry: 2.0
species: 741332

840171
type: SpeciesReference
stoichiometry: 1.0
species: 733323

733323
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Cholesta-7,24-dien-3beta-ol_C27H44O

840147
type: SpeciesReference
stoichiometry: 1.0
species: 745375

745375
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _5alpha-Cholest-7-en-3beta-ol_C27H46O

840231
type: SpeciesReference
stoichiometry: 2.0
species: 747148

747148
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

840207
type: SpeciesReference
stoichiometry: 4.0
species: 741223

840243
type: SpeciesReference
stoichiometry: 1.0
species: 729102

729102
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _7-Dehydrocholesterol_C27H44O

840183
type: SpeciesReference
stoichiometry: 2.0
species: 747209

747209
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

840159
type: SpeciesReference
stoichiometry: 2.0
species: 747746

747746
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: O2_O2

840219
type: SpeciesReference
stoichiometry: 1.0
species: 735853

735853
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _7-Dehydrodesmosterol_C27H42O

746473
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1D-myo-Inositol 1,4,5-trisphosphate_C6H9O15P3

751941
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Tetradecanoyl-CoA (n-C14:0CoA)_C35H58N7O17P3S

741596
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113

036119
type: Reaction
name: _3-Dehydrosphinganine reductase
reactant: 806785
reactant: 806761
product: 806809
fast: false
notes: R_3DSPHR subsystem: Sphingolipid Metabolism R_3DSPHR equation: [c] : 3dsphgn + h + nadph --> nadp + sphgn
is: http://identifiers.org/ec-code/1.1.1.102
is: ENSCAFG00000000067.2
reactant: 806773
reversible: false
product: 806797

806785
type: SpeciesReference
stoichiometry: 1.0
species: 747173

806761
type: SpeciesReference
stoichiometry: 1.0
species: 727323

806809
type: SpeciesReference
stoichiometry: 1.0
species: 747099

806773
type: SpeciesReference
stoichiometry: 1.0
species: 741259

806797
type: SpeciesReference
stoichiometry: 1.0
species: 751288

751288
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Sphinganine_C18H40NO2

750794
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: de-Fuc, reducing GlcNAc removed form of PA6 (w/o peptide linkage)_C76H123N5O57

745555
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Mannosyl)4-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1540H2528N20O420P20

748411
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)_C9H13O18P4FULLRCO2FULLR2CO2

036289
type: Reaction
reactant: 808133
product: 808169
reversible: false
fast: false
product: 808157
product: 808193
is: ENSCAFG00000000926.2
notes: R_34DHPHAMT subsystem: Tyrosine metabolism R_34DHPHAMT equation: [c] : 34dhpha + amet --> ahcys + h + homoval R_DOPAMT subsystem: Tyrosine metabolism R_DOPAMT equation: [c] : amet + dopa --> 3moxtyr + ahcys + h R_SALMCOM subsystem: Tyrosine metabolism R_SALMCOM equation: [c] : amet + nrpphr --> ahcys + h + normete-L
is: http://identifiers.org/ec-code/2.1.1.6
product: 808181
reactant: 808097
product: 808145
reactant: 808109
reactant: 808121

808133
type: SpeciesReference
stoichiometry: 1.0
species: 736983

808169
type: SpeciesReference
stoichiometry: 1.0
species: 747528

747528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Normetanephrine_C9H14NO3

808157
type: SpeciesReference
stoichiometry: 1.0
species: 741899

741899
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Homovanillate_C9H9O4

808193
type: SpeciesReference
stoichiometry: 3.0
species: 741259

808181
type: SpeciesReference
stoichiometry: 1.0
species: 727672

727672
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Methoxytyramine_C9H14NO2

808097
type: SpeciesReference
stoichiometry: 1.0
species: 747553

808145
type: SpeciesReference
stoichiometry: 3.0
species: 731273

731273
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

808109
type: SpeciesReference
stoichiometry: 3.0
species: 731694

731694
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: S-Adenosyl-L-methionine_C15H23N6O5S

808121
type: SpeciesReference
stoichiometry: 1.0
species: 727130

727130
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3,4-Dihydroxyphenylacetate_C8H7O4

750333
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Pyridoxine_C8H11NO3

039152
type: Reaction
fast: false
reactant: 835027
notes: R_UGALNACter subsystem: Transport, Endoplasmic Reticular R_UGALNACter equation: udpacgal[c] + ump[r] <==> udpacgal[r] + ump[c] R_UDPGLCAter subsystem: Transport, Endoplasmic Reticular R_UDPGLCAter equation: udpglcur[r] + ump[c] <==> udpglcur[c] + ump[r]
product: 835051
reactant: 835003
product: 835039
product: 835075
is: ENSCAFG00000018543.2
product: 835063
reactant: 834991
reversible: true
reactant: 835015

835027
type: SpeciesReference
stoichiometry: 1.0
species: 753218

835051
type: SpeciesReference
stoichiometry: 1.0
species: 753471

753471
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: UMP_C9H11N2O9P

835003
type: SpeciesReference
stoichiometry: 1.0
species: 753471

835039
type: SpeciesReference
stoichiometry: 1.0
species: 753399

835075
type: SpeciesReference
stoichiometry: 1.0
species: 753326

753326
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: UDP-D-glucuronate_C15H19N2O18P2

835063
type: SpeciesReference
stoichiometry: 1.0
species: 753254

753254
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065

834991
type: SpeciesReference
stoichiometry: 1.0
species: 753399

835015
type: SpeciesReference
stoichiometry: 1.0
species: 753350

753350
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: UDP-D-glucuronate_C15H19N2O18P2

037617
type: Reaction
product: 820655
product: 820691
product: 820679
product: 820667
notes: R_P45011B11m subsystem: Steroid Metabolism R_P45011B11m equation: [m] : 11docrtstrn + h + nadph + o2 --> crtstrn + h2o + nadp R_P45011B12m subsystem: Steroid Metabolism R_P45011B12m equation: [m] : 11docrtsl + h + nadph + o2 --> crtsl + h2o + nadp
reversible: false
reactant: 820630
is: http://identifiers.org/ec-code/1.14.15.4
reactant: 820606
reactant: 820618
is: ENSCAFG00000001285.2
fast: false
reactant: 820642
reactant: 820594

820655
type: SpeciesReference
stoichiometry: 1.0
species: 734405

734405
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Cortisol_C21H30O5

820691
type: SpeciesReference
stoichiometry: 2.0
species: 747123

747123
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

820679
type: SpeciesReference
stoichiometry: 1.0
species: 734429

734429
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Corticosterone_C21H30O4

820667
type: SpeciesReference
stoichiometry: 2.0
species: 741199

820630
type: SpeciesReference
stoichiometry: 2.0
species: 747722

747722
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: O2_O2

820606
type: SpeciesReference
stoichiometry: 1.0
species: 726343

820618
type: SpeciesReference
stoichiometry: 2.0
species: 747185

747185
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

820642
type: SpeciesReference
stoichiometry: 2.0
species: 741308

820594
type: SpeciesReference
stoichiometry: 1.0
species: 726368

744796
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Leucine_C6H13NO2

039116
type: Reaction
notes: R_ACS2 subsystem: Propanoate Metabolism R_ACS2 equation: [c] : atp + coa + ppa --> amp + ppcoa + ppi R_ACCOAL subsystem: Propanoate Metabolism R_ACCOAL equation: [c] : atp + coa + ppa --> adp + pi + ppcoa R_ACS subsystem: Glycolysis/Gluconeogenesis R_ACS equation: [c] : ac + atp + coa --> accoa + amp + ppi
reactant: 834566
product: 834665
reversible: false
fast: false
product: 834639
is: http://identifiers.org/ec-code/6.2.1.1
product: 834626
reactant: 834590
product: 834652
product: 834602
reactant: 834578
product: 834614
reactant: 834554
is: http://identifiers.org/ec-code/6.2.1.13
is: ENSCAFG00000007637.2

834566
type: SpeciesReference
stoichiometry: 1.0
species: 729979

834665
type: SpeciesReference
stoichiometry: 2.0
species: 749466

834639
type: SpeciesReference
stoichiometry: 1.0
species: 730124

834626
type: SpeciesReference
stoichiometry: 2.0
species: 749430

749430
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Propanoyl-CoA_C24H36N7O17P3S

834590
type: SpeciesReference
stoichiometry: 2.0
species: 749394

749394
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Propionate (n-C3:0)_C3H5O2

834652
type: SpeciesReference
stoichiometry: 2.0
species: 731755

834602
type: SpeciesReference
stoichiometry: 1.0
species: 749200

834578
type: SpeciesReference
stoichiometry: 3.0
species: 732441

834614
type: SpeciesReference
stoichiometry: 1.0
species: 730922

834554
type: SpeciesReference
stoichiometry: 3.0
species: 734054

726584
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _1-alpha,25-Dihydroxyvitamin D2_C28H44O3

735457
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dAMP_C10H12N5O6P

035469
type: Reaction
notes: R_ADSL2 subsystem: IMP Biosynthesis R_ADSL2 equation: [c] : 25aics --> aicar + fum R_ADSL1 subsystem: Nucleotides R_ADSL1 equation: [c] : dcamp --> amp + fum
product: 800714
product: 800738
is: ENSCAFG00000001206.2
product: 800726
fast: false
reversible: false
reactant: 800690
is: http://identifiers.org/ec-code/4.3.2.2
reactant: 800702

800714
type: SpeciesReference
stoichiometry: 1.0
species: 731345

731345
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide_C9H13N4O8P

800738
type: SpeciesReference
stoichiometry: 1.0
species: 731755

800726
type: SpeciesReference
stoichiometry: 2.0
species: 738822

738822
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Fumarate_C4H2O4

800690
type: SpeciesReference
stoichiometry: 1.0
species: 726742

726742
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate_C13H15N4O12P

800702
type: SpeciesReference
stoichiometry: 1.0
species: 735541

735541
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N6-(1,2-Dicarboxyethyl)-AMP_C14H14N5O11P

737774
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _16-Glucuronide-estriol_C24H32O9

737448
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _8,9 epxoy aflatoxin B1_C17H12O7

037026
type: Reaction
reactant: 813759
reactant: 813747
fast: false
product: 813808
product: 813784
notes: R_PROSTGF2t subsystem: Transport, Extracellular R_PROSTGF2t equation: prostgf2[e] <==> prostgf2[c] R_SRTNtu subsystem: Transport, Extracellular R_SRTNtu equation: srtn[e] <==> srtn[c] R_PROSTGE2t2 subsystem: Transport, Extracellular R_PROSTGE2t2 equation: prostge2[e] <==> prostge2[c]
is: ENSCAFG00000000750.2
product: 813796
reactant: 813772
reversible: true

813759
type: SpeciesReference
stoichiometry: 1.0
species: 750020

750020
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Prostaglandin E2_C20H31O5

813747
type: SpeciesReference
stoichiometry: 1.0
species: 751458

751458
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Serotonin_C10H13N2O

813808
type: SpeciesReference
stoichiometry: 1.0
species: 751446

751446
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Serotonin_C10H13N2O

813784
type: SpeciesReference
stoichiometry: 1.0
species: 750008

750008
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Prostaglandin E2_C20H31O5

813796
type: SpeciesReference
stoichiometry: 1.0
species: 750044

750044
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Prostaglandin F2alpha_C20H33O5

813772
type: SpeciesReference
stoichiometry: 1.0
species: 750056

750056
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Prostaglandin F2alpha_C20H33O5

731477
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: beta-Alanine_C3H7NO2

030429
type: Reaction
product: 754512
reactant: 754464
product: 754500
reactant: 754476
reversible: false
is: http://identifiers.org/ec-code/3.1.1.23
fast: false
name: lipase
product: 754488
is: ENSCAFG00000004093.2
notes: R_LPS3 subsystem: Triacylglycerol Synthesis R_LPS3 equation: [c] : h2o + mag_hs --> Rtotal2 + glyc + h

754512
type: SpeciesReference
stoichiometry: 1.0
species: 740313

740313
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Glycerol_C3H8O3

754464
type: SpeciesReference
stoichiometry: 1.0
species: 745856

745856
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: monoacylglycerol 2 (homo sapiens)_C3H7O2FULLR2CO2

754500
type: SpeciesReference
stoichiometry: 1.0
species: 741259

754476
type: SpeciesReference
stoichiometry: 1.0
species: 741151

754488
type: SpeciesReference
stoichiometry: 1.0
species: 729513

746653
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (S)-Methylmalonyl-CoA_C25H35N7O19P3S

742127
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 20_C45H68N2O43S2

754171
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane_C27H48O3

034577
type: Reaction
product: 791738
notes: R_GTHO subsystem: Glutamate metabolism R_GTHO equation: [c] : gthox + h + nadph --> (2) gthrd + nadp R_GTHOm subsystem: Glutamate metabolism R_GTHOm equation: [m] : gthox + h + nadph --> (2) gthrd + nadp
fast: false
reactant: 791678
is: http://identifiers.org/ec-code/1.8.1.7
product: 791726
product: 791714
is: ENSCAFG00000004386.2
reversible: false
reactant: 791666
reactant: 791642
reactant: 791654
reactant: 791630
reactant: 791690
product: 791702

791738
type: SpeciesReference
stoichiometry: 1.0
species: 747123

791678
type: SpeciesReference
stoichiometry: 1.0
species: 741259

791726
type: SpeciesReference
stoichiometry: 2.0
species: 740946

740946
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Reduced glutathione_C10H16N3O6S

791714
type: SpeciesReference
stoichiometry: 2.0
species: 740922

791666
type: SpeciesReference
stoichiometry: 1.0
species: 741308

791642
type: SpeciesReference
stoichiometry: 1.0
species: 740910

740910
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Oxidized glutathione_C20H30N6O12S2

791654
type: SpeciesReference
stoichiometry: 1.0
species: 747185

791630
type: SpeciesReference
stoichiometry: 1.0
species: 740886

740886
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Oxidized glutathione_C20H30N6O12S2

791690
type: SpeciesReference
stoichiometry: 1.0
species: 747173

791702
type: SpeciesReference
stoichiometry: 1.0
species: 747099

742467
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 8_C79H116N4O64X

740518
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: ganglioside GM3 (homo sapiens)_C41H72N2O20FULLRCO

035481
type: Reaction
product: 800786
reactant: 800762
reversible: false
reactant: 800750
is: http://identifiers.org/ec-code/3.1.3.46
is: ENSCAFG00000023446.1
fast: false
notes: R_FBP26 subsystem: Fructose and Mannose Metabolism R_FBP26 equation: [c] : f26bp + h2o --> f6p + pi R_FBP subsystem: Glycolysis/Gluconeogenesis R_FBP equation: [c] : fdp + h2o --> f6p + pi
reactant: 800774
is: ENSCAFG00000001305.2
is: http://identifiers.org/ec-code/3.1.3.11
product: 800798

800786
type: SpeciesReference
stoichiometry: 2.0
species: 749200

800762
type: SpeciesReference
stoichiometry: 1.0
species: 738171

738171
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Fructose 1,6-bisphosphate_C6H10O12P2

800750
type: SpeciesReference
stoichiometry: 1.0
species: 737991

737991
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Fructose 2,6-bisphosphate_C6H10O12P2

800774
type: SpeciesReference
stoichiometry: 2.0
species: 741151

800798
type: SpeciesReference
stoichiometry: 2.0
species: 738015

738015
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Fructose 6-phosphate_C6H11O9P

033390
type: Reaction
product: 781012
name: mevalonate kinase (atp)
product: 781024
reactant: 780988
is: http://identifiers.org/ec-code/2.7.1.36
fast: false
reactant: 781000
is: ENSCAFG00000010834.2
product: 781036
notes: R_MEVK1x subsystem: Cholesterol Metabolism R_MEVK1x equation: [x] : atp + mev-R --> 5pmev + adp + h
reversible: false

781012
type: SpeciesReference
stoichiometry: 1.0
species: 728848

728848
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: (R)-5-Phosphomevalonate_C6H10O7P

781024
type: SpeciesReference
stoichiometry: 1.0
species: 741344

780988
type: SpeciesReference
stoichiometry: 1.0
species: 732501

732501
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: ATP_C10H12N5O13P3

781000
type: SpeciesReference
stoichiometry: 1.0
species: 746352

746352
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: (R)-Mevalonate_C6H11O4

781036
type: SpeciesReference
stoichiometry: 1.0
species: 730982

730982
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: ADP_C10H12N5O10P2

034420
type: Reaction
is: ENSCAFG00000023358.1
product: 789723
reactant: 789663
product: 789699
fast: false
product: 789711
reactant: 789675
reactant: 789687
notes: R_NRPPHRtu subsystem: Transport, Extracellular R_NRPPHRtu equation: nrpphr[e] <==> nrpphr[c] R_DOPAtu subsystem: Transport, Extracellular R_DOPAtu equation: dopa[e] <==> dopa[c] R_HISTAtu subsystem: Transport, Extracellular R_HISTAtu equation: hista[e] <==> hista[c]
reversible: true

789723
type: SpeciesReference
stoichiometry: 1.0
species: 736983

789663
type: SpeciesReference
stoichiometry: 1.0
species: 736995

789699
type: SpeciesReference
stoichiometry: 1.0
species: 747553

789711
type: SpeciesReference
stoichiometry: 1.0
species: 741777

741777
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Histamine_C5H10N3

789675
type: SpeciesReference
stoichiometry: 1.0
species: 741790

741790
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Histamine_C5H10N3

789687
type: SpeciesReference
stoichiometry: 1.0
species: 747565

033900
type: Reaction
notes: R_PNTK subsystem: CoA Biosynthesis R_PNTK equation: [c] : atp + pnto-R --> 4ppan + adp + h
product: 784923
reversible: false
product: 784911
is: ENSCAFG00000017049.2
product: 784935
is: ENSCAFG00000019416.2
is: http://identifiers.org/ec-code/2.7.1.33
fast: false
is: ENSCAFG00000007165.2
reactant: 784887
name: pantothenate kinase
reactant: 784899

784923
type: SpeciesReference
stoichiometry: 1.0
species: 728293

728293
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-4'-Phosphopantothenate_C9H15NO8P

784911
type: SpeciesReference
stoichiometry: 1.0
species: 730922

784935
type: SpeciesReference
stoichiometry: 1.0
species: 741259

784887
type: SpeciesReference
stoichiometry: 1.0
species: 749358

749358
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (R)-Pantothenate_C9H16NO5

784899
type: SpeciesReference
stoichiometry: 1.0
species: 732441

752193
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Tetracosatetraenoyl carnitine_C31H53NO4

743781
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 1_C79H129N5O57X

747890
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _9-O-Acetylated GT3 (homo sapiens)_C65H106N4O37FULLRCO

731779
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: AMP_C10H12N5O7P

039262
type: Reaction
product: 836592
fast: false
reversible: true
product: 836556
is: http://identifiers.org/ec-code/2.6.1.42
product: 836580
product: 836568
reactant: 836520
reactant: 836508
reactant: 836544
reactant: 836532
is: ENSCAFG00000011487.2
notes: R_ILETA subsystem: Valine, Leucine, and Isoleucine Metabolism R_ILETA equation: [c] : akg + ile-L <==> 3mop + glu-L R_VALTA subsystem: Valine, Leucine, and Isoleucine Metabolism R_VALTA equation: [c] : akg + val-L <==> 3mob + glu-L R_LEUTA subsystem: Valine, Leucine, and Isoleucine Metabolism R_LEUTA equation: [c] : akg + leu-L <==> 4mop + glu-L
is: http://identifiers.org/ec-code/2.6.1.6

836592
type: SpeciesReference
stoichiometry: 1.0
species: 728197

728197
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Methyl-2-oxopentanoate_C6H9O3

836556
type: SpeciesReference
stoichiometry: 1.0
species: 727600

727600
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Methyl-2-oxobutanoate_C5H7O3

836580
type: SpeciesReference
stoichiometry: 3.0
species: 739987

836568
type: SpeciesReference
stoichiometry: 1.0
species: 727624

727624
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (S)-3-Methyl-2-oxopentanoate_C6H9O3

836520
type: SpeciesReference
stoichiometry: 1.0
species: 753750

753750
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Valine_C5H11NO2

836508
type: SpeciesReference
stoichiometry: 3.0
species: 731405

731405
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2-Oxoglutarate_C5H4O5

836544
type: SpeciesReference
stoichiometry: 1.0
species: 744784

744784
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Leucine_C6H13NO2

836532
type: SpeciesReference
stoichiometry: 1.0
species: 742758

742758
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Isoleucine_C6H13NO2

035636
type: Reaction
product: 802000
reactant: 801976
reactant: 801952
reversible: true
reactant: 801940
product: 801989
is: ENSCAFG00000005661.2
reactant: 801964
product: 802012
fast: false
notes: R_ECOAH1x subsystem: Tryptophan metabolism R_ECOAH1x equation: [x] : 3hbcoa <==> b2coa + h2o R_C2M26DCOAHLx subsystem: Limonene and pinene degradation R_C2M26DCOAHLx equation: [x] : c2m26dcoa + h2o <==> 3h26dm5coa R_T2M26DCOAHLx subsystem: Limonene and pinene degradation R_T2M26DCOAHLx equation: [x] : h2o + t2m26dcoa <==> 3h26dm5coa
is: http://identifiers.org/ec-code/4.2.1.17

802000
type: SpeciesReference
stoichiometry: 1.0
species: 732525

732525
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Crotonoyl-CoA_C25H36N7O17P3S

801976
type: SpeciesReference
stoichiometry: 1.0
species: 751735

751735
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137

801952
type: SpeciesReference
stoichiometry: 1.0
species: 732985

732985
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137

801940
type: SpeciesReference
stoichiometry: 2.0
species: 741235

801989
type: SpeciesReference
stoichiometry: 1.0
species: 741235

801964
type: SpeciesReference
stoichiometry: 1.0
species: 727396

727396
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137

802012
type: SpeciesReference
stoichiometry: 2.0
species: 727347

727347
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137

742552
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Hypoxanthine_C5H4N4O

749285
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Phosphate_HO4P

736740
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Dimethylallyl diphosphate_C5H9O7P2

746605
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5,10-Methylenetetrahydrofolate_C20H21N7O6

748483
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1-Phosphatidyl-1D-myo-inositol 3-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

034987
type: Reaction
reactant: 794670
product: 794707
notes: R_34HPPOR subsystem: Tyrosine metabolism R_34HPPOR equation: [c] : 34hpp + o2 --> co2 + hgentis R_PPOR subsystem: Phenylalanine metabolism R_PPOR equation: [c] : o2 + phpyr --> 2hyoxplac + co2
product: 794695
product: 794682
reactant: 794646
fast: false
reactant: 794658
is: ENSCAFG00000008093.2
is: http://identifiers.org/ec-code/1.13.11.27
reversible: false

794670
type: SpeciesReference
stoichiometry: 2.0
species: 747698

794707
type: SpeciesReference
stoichiometry: 2.0
species: 733981

794695
type: SpeciesReference
stoichiometry: 1.0
species: 726937

726937
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2-Hydroxyphenylacetate_C8H7O3

794682
type: SpeciesReference
stoichiometry: 1.0
species: 741741

741741
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Homogentisate_C8H7O4

794646
type: SpeciesReference
stoichiometry: 1.0
species: 749116

749116
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Phenylpyruvate_C9H7O3

794658
type: SpeciesReference
stoichiometry: 1.0
species: 727166

727166
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-(4-Hydroxyphenyl)pyruvate_C9H7O4

040368
type: Reaction
reversible: true
product: 846318
reactant: 846306
reactant: 846294
fast: false
is: http://identifiers.org/ec-code/1.1.1.105
is: ENSCAFG00000000148.2
name: retinol dehydrogenase (all-trans)
notes: R_RDH1 subsystem: Vitamin A Metabolism R_RDH1 equation: [c] : nad + retinol <==> h + nadh + retinal
product: 846330
product: 846342

846318
type: SpeciesReference
stoichiometry: 1.0
species: 750562

750562
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Retinal_C20H28O

846306
type: SpeciesReference
stoichiometry: 1.0
species: 750610

846294
type: SpeciesReference
stoichiometry: 1.0
species: 746978

846330
type: SpeciesReference
stoichiometry: 1.0
species: 741259

846342
type: SpeciesReference
stoichiometry: 1.0
species: 747050

744012
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 3_C93H152N6O67X

032246
type: Reaction
product: 771214
fast: false
reactant: 771166
is: http://identifiers.org/ec-code/1.2.3.1
is: ENSCAFG00000023664.1
product: 771239
reactant: 771190
reversible: false
reactant: 771178
product: 771226
reactant: 771202
notes: R_PYDXDH subsystem: Vitamin B6 Metabolism R_PYDXDH equation: [c] : h2o + o2 + pydx --> 4pyrdx + h2o2 R_5HOXINDACTO2OX subsystem: Tryptophan metabolism R_5HOXINDACTO2OX equation: [c] : 5hoxindact + h2o + o2 --> 5hoxindoa + h + h2o2
is: ENSCAFG00000025299.1
is: ENSCAFG00000011544.2
product: 771251

771214
type: SpeciesReference
stoichiometry: 1.0
species: 728692

771166
type: SpeciesReference
stoichiometry: 1.0
species: 750321

750321
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Pyridoxal_C8H9NO3

771239
type: SpeciesReference
stoichiometry: 2.0
species: 741078

741078
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Hydrogen peroxide_H2O2

771190
type: SpeciesReference
stoichiometry: 2.0
species: 741151

771178
type: SpeciesReference
stoichiometry: 1.0
species: 728668

771226
type: SpeciesReference
stoichiometry: 1.0
species: 728329

728329
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Pyridoxate_C8H9NO4

771202
type: SpeciesReference
stoichiometry: 2.0
species: 747698

771251
type: SpeciesReference
stoichiometry: 1.0
species: 741259

738231
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide_C8H13N2O9P

727540
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Methoxy-4-hydroxyphenylglycolaldehyde_C9H10O4

743168
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 14_C166H267N11O145S8

744928
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: lignoceric acid_C24H47O2

031427
type: Reaction
notes: R_B3GALT3g subsystem: Sphingolipid Metabolism R_B3GALT3g equation: [g] : thcrm_hs + udpacgal --> gbside_hs + h + udp
reversible: false
product: 763476
reactant: 763439
product: 763464
is: ENSCAFG00000014327.1
name: Beta-1,3-galactosyltransferase 3
fast: false
reactant: 763427
product: 763452
is: http://identifiers.org/ec-code/2.4.1.79

763476
type: SpeciesReference
stoichiometry: 1.0
species: 739462

739462
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: globoside (homo sapiens)_C44H79N2O22FULLRCO

763439
type: SpeciesReference
stoichiometry: 1.0
species: 752325

752325
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: trihexosyl ceramide (homo sapiens)_C36H66NO17FULLRCO

763464
type: SpeciesReference
stoichiometry: 1.0
species: 741283

763427
type: SpeciesReference
stoichiometry: 1.0
species: 753230

763452
type: SpeciesReference
stoichiometry: 1.0
species: 753157

728257
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _4-Methylzymosterol intermediate 2_C28H44O

747197
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

751263
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Sphinganine 1-phosphate_C18H39NO5P

750490
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: alpha-D-Ribose 5-phosphate_C5H9O8P

730439
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: beta GalNAc globoside (homo sapiens)_C52H92N3O27FULLRCO

035179
type: Reaction
fast: false
reversible: false
reactant: 796950
product: 796962
is: ENSCAFG00000004407.2
product: 796975
name: malic enzyme (NADP), mitochondrial
product: 796988
notes: R_ME2m subsystem: Pyruvate Metabolism R_ME2m equation: [m] : mal-L + nadp --> co2 + nadph + pyr
is: http://identifiers.org/ec-code/1.1.1.40
reactant: 796938

796950
type: SpeciesReference
stoichiometry: 1.0
species: 747123

796962
type: SpeciesReference
stoichiometry: 1.0
species: 734005

734005
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: CO2_CO2

796975
type: SpeciesReference
stoichiometry: 1.0
species: 750393

750393
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Pyruvate_C3H3O3

796988
type: SpeciesReference
stoichiometry: 1.0
species: 747185

796938
type: SpeciesReference
stoichiometry: 1.0
species: 745916

036507
type: Reaction
modifier: 809603
notes: R_RDH2a subsystem: Vitamin A Metabolism R_RDH2a equation: [c] : nadp + retinol-9-cis <==> h + nadph + retinal-cis-9 R_RDH3a subsystem: Vitamin A Metabolism R_RDH3a equation: [c] : nadp + retinol-cis-11 <==> h + nadph + retinal-11-cis R_RDH1a subsystem: Vitamin A Metabolism R_RDH1a equation: [c] : nadp + retinol <==> h + nadph + retinal R_NTD11 subsystem: Purine Catabolism R_NTD11 equation: [c] : h2o + imp --> ins + pi R_NTD3 subsystem: Pyrimidine Catabolism R_NTD3 equation: [c] : dcmp + h2o --> dcyt + pi R_NTD7 subsystem: Nucleotides R_NTD7 equation: [c] : amp + h2o --> adn + pi
product: 809519
modifier: 809639
modifier: 809591
modifier: 809567
reversible: false
product: 809495
reactant: 809459
modifier: 809627
fast: false
is: ENSCAFG00000003760.2
reactant: 809471
modifier: 809579
modifier: 809555
product: 809531
modifier: 809543
is: http://identifiers.org/ec-code/3.1.3.5
reactant: 809446
modifier: 809615
is: http://identifiers.org/ec-code/1.1.1.105
product: 809507
reactant: 809483

809519
type: SpeciesReference
stoichiometry: 1.0
species: 742916

742916
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Inosine_C10H12N4O5

809495
type: SpeciesReference
stoichiometry: 3.0
species: 749200

809459
type: SpeciesReference
stoichiometry: 3.0
species: 741151

750526
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cis-11-retinal_C20H28O

809471
type: SpeciesReference
stoichiometry: 1.0
species: 731755

750586
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cis-11-retinol_C20H30O

809531
type: SpeciesReference
stoichiometry: 1.0
species: 735745

735745
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Deoxycytidine_C9H13N3O4

750574
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _9-cis-retinol_C20H30O

809446
type: SpeciesReference
stoichiometry: 1.0
species: 742843

809507
type: SpeciesReference
stoichiometry: 1.0
species: 730862

730862
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Adenosine_C10H13N5O4

809483
type: SpeciesReference
stoichiometry: 1.0
species: 735601

735601
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dCMP_C9H12N3O7P

733081
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: beta-Carotene_C40H56

036676
type: Reaction
product: 810880
name: UDP-D-glucuronate:galactosylgalactosylxylose glucuronosyltransferase, Golgi apparatus
is: ENSCAFG00000009677.2
is: http://identifiers.org/ec-code/2.4.1.135
product: 810892
is: ENSCAFG00000002616.2
reactant: 810868
product: 810904
fast: false
notes: R_GLCATg subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCATg equation: [g] : l2xser + udpglcur --> cs,hs_linkage + h + udp
reactant: 810856
reversible: false
is: ENSCAFG00000015783.2

810880
type: SpeciesReference
stoichiometry: 1.0
species: 753157

810892
type: SpeciesReference
stoichiometry: 1.0
species: 741283

810868
type: SpeciesReference
stoichiometry: 1.0
species: 753338

753338
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: UDP-D-glucuronate_C15H19N2O18P2

810904
type: SpeciesReference
stoichiometry: 1.0
species: 734465

734465
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate/heparan sulfate linkage region (GlcA-(Gal)2-Xyl-L-Ser (protein))_C23H36O20X

810856
type: SpeciesReference
stoichiometry: 1.0
species: 744585

752866
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Testosterone_C19H28O2

752157
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosatetraenoyl coenzyme A_C45H70N7O17P3S

733542
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Choline phosphate_C5H13NO4P

753762
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Valine_C5H11NO2

730524
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053

745266
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: gamma-linolenoyl-CoA_C39H60N7O17P3S

035191
type: Reaction
product: 797036
product: 797060
reactant: 797012
is: ENSCAFG00000014423.2
notes: R_ST3GAL61g subsystem: Blood Group Biosynthesis R_ST3GAL61g equation: [g] : cmpacna + gal14acglcgalgluside_hs --> acngal14acglcgalgluside_hs + cmp + h R_ST3GAL62g subsystem: Blood Group Biosynthesis R_ST3GAL62g equation: [g] : cmpacna + galacglcgal14acglcgalgluside_hs --> acngalacglcgal14acglcgalgluside_hs + cmp + h
reactant: 797024
is: ENSCAFG00000004982.2
product: 797048
reversible: false
fast: false
reactant: 797000
product: 797072

797036
type: SpeciesReference
stoichiometry: 1.0
species: 730693

730693
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089

797060
type: SpeciesReference
stoichiometry: 1.0
species: 730705

730705
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: VI3NeuAc-nLc6Cer_C69H118N4O40FULLRCO

797012
type: SpeciesReference
stoichiometry: 2.0
species: 733933

733933
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: CMP-N-acetylneuraminate_C20H29N4O16P

797024
type: SpeciesReference
stoichiometry: 1.0
species: 739196

739196
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: i-antigen_C58H102N3O32FULLRCO

797048
type: SpeciesReference
stoichiometry: 2.0
species: 741283

797000
type: SpeciesReference
stoichiometry: 1.0
species: 739099

739099
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089

797072
type: SpeciesReference
stoichiometry: 2.0
species: 733884

733884
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: CMP_C9H12N3O8P

738846
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: glucosyl-(alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C64H107N2O50X

726839
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _2-Decaprenyl-6-methoxyphenol_C57H88O2

041238
type: Reaction
notes: R_SPRMS subsystem: Urea cycle/amino group metabolism R_SPRMS equation: [c] : ametam + spmd --> 5mta + h + sprm
reversible: false
product: 855689
product: 855665
reactant: 855641
reactant: 855653
is: ENSCAFG00000013284.2
is: http://identifiers.org/ec-code/2.5.1.22
product: 855677
name: spermine synthase
fast: false

855689
type: SpeciesReference
stoichiometry: 1.0
species: 741259

855665
type: SpeciesReference
stoichiometry: 1.0
species: 728800

728800
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Methylthioadenosine_C11H15N5O3S

855641
type: SpeciesReference
stoichiometry: 1.0
species: 751410

751410
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Spermidine_C7H22N3

855653
type: SpeciesReference
stoichiometry: 1.0
species: 731743

731743
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: S-Adenosylmethioninamine_C14H24N6O3S

855677
type: SpeciesReference
stoichiometry: 1.0
species: 751422

751422
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Spermine_C10H30N4

039995
type: Reaction
is: ENSCAFG00000007417.2
fast: false
reversible: false
product: 842326
reactant: 842302
is: http://identifiers.org/ec-code/3.2.1.114
notes: R_M1316Mg subsystem: N-Glycan Biosynthesis R_M1316Mg equation: [g] : (2) h2o + nm4masn --> (2) man + nm2masn
product: 842338
is: ENSCAFG00000012259.2
name: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
reactant: 842314

842326
type: SpeciesReference
stoichiometry: 1.0
species: 747430

842302
type: SpeciesReference
stoichiometry: 2.0
species: 741175

842338
type: SpeciesReference
stoichiometry: 2.0
species: 746086

842314
type: SpeciesReference
stoichiometry: 1.0
species: 747442

747442
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C54H90N3O40X

749249
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Phosphate_HO4P

039503
type: Reaction
product: 838613
notes: R_SPTix subsystem: Glycine, Serine, and Threonine Metabolism R_SPTix equation: [x] : pyr + ser-L --> ala-L + hpyr R_AGTix subsystem: Alanine and Aspartate Metabolism R_AGTix equation: [x] : ala-L + glx --> gly + pyr
is: http://identifiers.org/ec-code/2.6.1.44
fast: false
product: 838601
reactant: 838565
reactant: 838589
reversible: false
product: 838638
is: ENSCAFG00000012744.2
product: 838626
reactant: 838553
reactant: 838577

838613
type: SpeciesReference
stoichiometry: 1.0
species: 731597

731597
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: L-Alanine_C3H7NO2

838601
type: SpeciesReference
stoichiometry: 1.0
species: 741983

741983
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Hydroxypyruvate_C3H3O4

838565
type: SpeciesReference
stoichiometry: 1.0
species: 740156

838589
type: SpeciesReference
stoichiometry: 1.0
species: 750405

838638
type: SpeciesReference
stoichiometry: 1.0
species: 750405

838626
type: SpeciesReference
stoichiometry: 1.0
species: 740217

740217
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Glycine_C2H5NO2

838553
type: SpeciesReference
stoichiometry: 1.0
species: 731597

838577
type: SpeciesReference
stoichiometry: 1.0
species: 751118

751118
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: L-Serine_C3H7NO3

736704
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S

032065
type: Reaction
product: 769384
reversible: false
fast: false
product: 769348
product: 769360
reactant: 769324
is: http://identifiers.org/ec-code/3.5.1.26
reactant: 769300
is: ENSCAFG00000008381.2
notes: R_GASNASE2ly subsystem: N-Glycan Degradation R_GASNASE2ly equation: [l] : h2o + n2m2nmasn --> Asn-X-Ser/Thr + n2m2nm R_GASNASE3ly subsystem: Keratan sulfate degradation R_GASNASE3ly equation: [l] : h2o + ksi_deg1 --> Asn-X-Ser/Thr + ksi_deg2 R_GASNASEly subsystem: N-Glycan Degradation R_GASNASEly equation: [l] : h2o + s2l2n2m2masn --> Asn-X-Ser/Thr + s2l2n2m2m
product: 769372
reactant: 769336
reactant: 769312

769384
type: SpeciesReference
stoichiometry: 1.0
species: 750757

750757
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: de-Fuc form of PA6 (w/o peptide linkage)_C84H136N6O62

769348
type: SpeciesReference
stoichiometry: 1.0
species: 746810

746810
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: n2m2nmasn (w/o peptide linkage)_C58H97N5O41

769360
type: SpeciesReference
stoichiometry: 3.0
species: 729234

729234
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: protein-linked asparagine residue (N-glycosylation site)_XH

769324
type: SpeciesReference
stoichiometry: 3.0
species: 741187

769300
type: SpeciesReference
stoichiometry: 1.0
species: 746834

746834
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-(N-acetyl-beta-D-glucosaminyl-1,4)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R_C58H96N5O40X

769372
type: SpeciesReference
stoichiometry: 1.0
species: 743384

743384
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 2_C241H384N17O210S12

769336
type: SpeciesReference
stoichiometry: 1.0
species: 743252

743252
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 1_C241H383N17O209S12X

769312
type: SpeciesReference
stoichiometry: 1.0
species: 750781

750781
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: de-Fuc form of PA6_C84H135N6O61X

747503
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Methylserotonin_C11H15N2O

726416
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _12 hydroxy arachidonic acid_C20H31O3

040645
type: Reaction
product: 850791
product: 850779
reactant: 850755
reactant: 850743
is: ENSCAFG00000011241.2
is: ENSCAFG00000024024.1
product: 850803
notes: R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_PROSTGE2t subsystem: Transport, Extracellular R_PROSTGE2t equation: hco3[c] + prostge2[e] <==> hco3[e] + prostge2[c]
reversible: true
fast: false
reactant: 850767

850791
type: SpeciesReference
stoichiometry: 1.0
species: 750008

850779
type: SpeciesReference
stoichiometry: 1.0
species: 737846

850755
type: SpeciesReference
stoichiometry: 1.0
species: 750020

850743
type: SpeciesReference
stoichiometry: 2.0
species: 741416

850803
type: SpeciesReference
stoichiometry: 2.0
species: 741428

850767
type: SpeciesReference
stoichiometry: 1.0
species: 737858

737858
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Estrone 3-sulfate_C18H21O5S

753435
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: UMP_C9H11N2O9P

732176
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: arachidonic acid_C20H31O2

745351
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: lysophosphatidylcholine (homo sapiens)_C8H19NO5PFULLRCO2

753603
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Uridine_C9H12N2O6

742188
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 25_C23H37O21

037604
type: Reaction
reactant: 820509
is: ENSCAFG00000002532.2
fast: false
reactant: 820533
product: 820546
product: 820558
is: http://identifiers.org/ec-code/2.4.1.132
reversible: false
notes: R_G13MT_L subsystem: N-Glycan Biosynthesis R_G13MT_L equation: [c] : gdpmann + (0.1) mpdol_L --> gdp + h + (0.1) m1mpdol_L R_G13MT_U subsystem: N-Glycan Biosynthesis R_G13MT_U equation: [c] : gdpmann + (0.1) mpdol_U --> gdp + h + (0.1) m1mpdol_U
product: 820570
reactant: 820521
product: 820582

820509
type: SpeciesReference
stoichiometry: 2.0
species: 739754

820533
type: SpeciesReference
stoichiometry: 1.0
species: 746726

820546
type: SpeciesReference
stoichiometry: 2.0
species: 739656

820558
type: SpeciesReference
stoichiometry: 1.0
species: 745447

745447
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: alpha-D-mannosyl-beta-D-mannosyl-diacylchitobiosyldiphosphodolichol, human liver homolog_C1360H2228N20O270P20

820570
type: SpeciesReference
stoichiometry: 2.0
species: 741259

820521
type: SpeciesReference
stoichiometry: 1.0
species: 746713

820582
type: SpeciesReference
stoichiometry: 1.0
species: 745459

745459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: alpha-D-mannosyl-beta-D-mannosyl-diacylchitobiosyldiphosphodolichol, human uterine homolog_C1305H2140N20O270P20

750647
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: retinoyl glucuronide_C26H35O8

747516
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Nitric oxide_NO

034204
type: Reaction
notes: R_METtec subsystem: Transport, Extracellular R_METtec equation: met-L[e] <==> met-L[c] R_ILEtec subsystem: Transport, Extracellular R_ILEtec equation: ile-L[e] <==> ile-L[c] R_LEUtec subsystem: Transport, Extracellular R_LEUtec equation: leu-L[e] <==> leu-L[c] R_VALtec subsystem: Transport, Extracellular R_VALtec equation: val-L[e] <==> val-L[c]
reversible: true
product: 787904
reactant: 787832
reactant: 787868
product: 787916
product: 787892
fast: false
reactant: 787856
reactant: 787844
is: ENSCAFG00000007862.2
product: 787880

787904
type: SpeciesReference
stoichiometry: 1.0
species: 746291

746291
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Methionine_C5H11NO2S

787832
type: SpeciesReference
stoichiometry: 1.0
species: 744796

787868
type: SpeciesReference
stoichiometry: 1.0
species: 742770

742770
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Isoleucine_C6H13NO2

787916
type: SpeciesReference
stoichiometry: 1.0
species: 744784

787892
type: SpeciesReference
stoichiometry: 1.0
species: 742758

787856
type: SpeciesReference
stoichiometry: 1.0
species: 753762

787844
type: SpeciesReference
stoichiometry: 1.0
species: 746303

746303
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Methionine_C5H11NO2S

787880
type: SpeciesReference
stoichiometry: 1.0
species: 753750

744084
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 9_C121H196N8O93S2X

729726
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: R total Coenzyme A_CO2FULLRC21H31N7O15P3S

733395
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Choline_C5H14NO

040188
type: Reaction
notes: R_ST6GALNAC62 subsystem: Sphingolipid Metabolism R_ST6GALNAC62 equation: [g] : cmpacna + gt1b_hs --> cmp + gq1balpha_hs + h R_ST6GALNAC61 subsystem: Sphingolipid Metabolism R_ST6GALNAC61 equation: [g] : cmpacna + gd1a_hs --> cmp + gt1alpha_hs + h R_ST6GALNAC31 subsystem: Sphingolipid Metabolism R_ST6GALNAC31 equation: [g] : cmpacna + gm1b_hs --> cmp + gd1alpha_hs + h
is: ENSCAFG00000020103.2
fast: false
reactant: 844446
product: 844507
reversible: false
reactant: 844471
product: 844543
reactant: 844459
reactant: 844483
product: 844519
product: 844531
product: 844495

844446
type: SpeciesReference
stoichiometry: 1.0
species: 739547

739547
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GD1a (homo sapiens)_C66H111N4O38FULLRCO

844507
type: SpeciesReference
stoichiometry: 1.0
species: 740699

740699
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GQ1balpha (homo sapiens)_C88H143N6O54FULLRCO

844471
type: SpeciesReference
stoichiometry: 1.0
species: 740481

740481
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GM1b (homo sapiens)_C55H95N3O30FULLRCO

844543
type: SpeciesReference
stoichiometry: 3.0
species: 733884

844459
type: SpeciesReference
stoichiometry: 3.0
species: 733933

844483
type: SpeciesReference
stoichiometry: 1.0
species: 740825

740825
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GT1b (homo sapiens)_C77H127N5O46FULLRCO

844519
type: SpeciesReference
stoichiometry: 1.0
species: 739559

739559
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GD1a (homo sapiens)_C66H111N4O38FULLRCO

844531
type: SpeciesReference
stoichiometry: 1.0
species: 740812

740812
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GT1aalpha (homo sapiens)_C77H127N5O46FULLRCO

844495
type: SpeciesReference
stoichiometry: 3.0
species: 741283

730838
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: acyl-dihydroxyacetone phosphate_C3H4O6PFULLRCO

740775
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Guanosine_C10H13N5O5

038453
type: Reaction
reversible: false
notes: R_MI4PP subsystem: Inositol Phosphate Metabolism R_MI4PP equation: [c] : h2o + mi4p-D --> inost + pi R_MI3PP subsystem: Inositol Phosphate Metabolism R_MI3PP equation: [c] : h2o + mi3p-D --> inost + pi R_MI1PP subsystem: Inositol Phosphate Metabolism R_MI1PP equation: [c] : h2o + mi1p-D --> inost + pi
fast: false
reactant: 829313
reactant: 829277
reactant: 829289
is: http://identifiers.org/ec-code/3.1.3.25
product: 829337
reactant: 829301
product: 829325
is: ENSCAFG00000018807.2

829313
type: SpeciesReference
stoichiometry: 3.0
species: 741151

829277
type: SpeciesReference
stoichiometry: 1.0
species: 746521

746521
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1D-myo-Inositol 1-phosphate_C6H11O9P

829289
type: SpeciesReference
stoichiometry: 1.0
species: 746557

746557
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1D-myo-Inositol 3-phosphate_C6H11O9P

829337
type: SpeciesReference
stoichiometry: 3.0
species: 742892

829301
type: SpeciesReference
stoichiometry: 1.0
species: 746569

746569
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1D-myo-Inositol 4-phosphate_C6H11O9P

829325
type: SpeciesReference
stoichiometry: 3.0
species: 749200

747601
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: nervonic acid_C24H45O2

739522
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: glycocholate_C26H43NO6

729319
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Cysteate_C3H6NO5S

036386
type: Reaction
product: 808830
reactant: 808818
notes: R_TYRASE subsystem: Tyrosine metabolism R_TYRASE equation: [c] : 56dihindlcrbxlt --> melanin
is: ENSCAFG00000001478.2
fast: false
reversible: false
name: Tyrosinase

808830
type: SpeciesReference
stoichiometry: 1.0
species: 746122

746122
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Melanin_C9H6NO4

808818
type: SpeciesReference
stoichiometry: 1.0
species: 728378

728378
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5,6-Dihydroxyindole-2-carboxylate_C9H6NO4

734707
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 4_C31H49NO29S

032342
type: Reaction
product: 772013
reactant: 772001
notes: R_TXASr subsystem: Eicosanoid Metabolism R_TXASr equation: [r] : prostgh2 --> txa2
is: ENSCAFG00000004011.2
is: http://identifiers.org/ec-code/5.3.99.5
fast: false
reversible: false
name: Thromboxane-A synthase

772013
type: SpeciesReference
stoichiometry: 1.0
species: 753034

753034
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Thromboxane A2_C20H31O5

772001
type: SpeciesReference
stoichiometry: 1.0
species: 750080

750080
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Prostaglandin H2_C20H31O5

751518
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: stearoylcarnitine_C25H49NO4

741054
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: carbonic acid_H2CO3

037714
type: Reaction
product: 822213
reactant: 822153
reactant: 822165
notes: R_ST3GAL31g subsystem: Blood Group Biosynthesis R_ST3GAL31g equation: [g] : cmpacna + galacglcgalgluside_hs --> acngalacglcgalgluside_hs + cmp + h R_S23T3g subsystem: Keratan sulfate biosynthesis R_S23T3g equation: [g] : cmpacna + l2fn2m2masn --> cmp + h + ksi_pre1
product: 822177
reversible: false
is: ENSCAFG00000004887.2
product: 822189
product: 822201
fast: false
is: http://identifiers.org/ec-code/2.4.99.6
reactant: 822141

822213
type: SpeciesReference
stoichiometry: 2.0
species: 733884

822153
type: SpeciesReference
stoichiometry: 1.0
species: 744546

744546
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089

822165
type: SpeciesReference
stoichiometry: 1.0
species: 739232

822177
type: SpeciesReference
stoichiometry: 1.0
species: 743781

822189
type: SpeciesReference
stoichiometry: 2.0
species: 741283

822201
type: SpeciesReference
stoichiometry: 1.0
species: 730717

730717
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)3 (Glc)1 (GlcNAc)1 (Cer)1_C55H95N3O30FULLRCO

822141
type: SpeciesReference
stoichiometry: 2.0
species: 733933

735312
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Cytidine_C9H13N3O5

033475
type: Reaction
fast: false
product: 781710
product: 781698
product: 781686
notes: R_CEPTE subsystem: Glycerophospholipid Metabolism R_CEPTE equation: [c] : cdpea + dag_hs --> cmp + h + pe_hs R_CEPTC subsystem: Glycerophospholipid Metabolism R_CEPTC equation: [c] : cdpchol + dag_hs --> cmp + h + pchol_hs
product: 781674
reactant: 781662
reactant: 781650
is: ENSCAFG00000019766.2
reactant: 781638
reversible: false

781710
type: SpeciesReference
stoichiometry: 2.0
species: 741259

781698
type: SpeciesReference
stoichiometry: 1.0
species: 748847

748847
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2

781686
type: SpeciesReference
stoichiometry: 1.0
species: 748699

781674
type: SpeciesReference
stoichiometry: 2.0
species: 733859

781662
type: SpeciesReference
stoichiometry: 1.0
species: 733262

733262
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: CDPethanolamine_C11H19N4O11P2

781650
type: SpeciesReference
stoichiometry: 1.0
species: 733226

733226
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: CDPcholine_C14H25N4O11P2

781638
type: SpeciesReference
stoichiometry: 2.0
species: 735409

735409
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2

726900
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2-Deoxy-D-ribose 5-phosphate_C5H9O7P

745423
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Lysine_C6H15N2O2

738377
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Formate_CH1O2

744724
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Lanosterol_C30H50O

735926
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137

736959
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dolichol phosphate, human uterine homolog_C1025H1670O40P10

037122
type: Reaction
is: http://identifiers.org/ec-code/2.7.1.32
reactant: 814771
product: 814831
fast: false
notes: R_ETHAK subsystem: Glycerophospholipid Metabolism R_ETHAK equation: [c] : atp + etha --> adp + ethamp + h R_CHOLK subsystem: Glycerophospholipid Metabolism R_CHOLK equation: [c] : atp + chol --> adp + cholp + h
product: 814819
is: ENSCAFG00000010937.2
product: 814807
reversible: false
is: http://identifiers.org/ec-code/2.7.1.82
product: 814795
reactant: 814783
reactant: 814759

814771
type: SpeciesReference
stoichiometry: 2.0
species: 732441

814831
type: SpeciesReference
stoichiometry: 2.0
species: 741259

814819
type: SpeciesReference
stoichiometry: 2.0
species: 730922

814807
type: SpeciesReference
stoichiometry: 1.0
species: 733516

733516
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Choline phosphate_C5H13NO4P

814795
type: SpeciesReference
stoichiometry: 1.0
species: 737919

737919
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Ethanolamine phosphate_C2H7NO4P

814783
type: SpeciesReference
stoichiometry: 1.0
species: 733335

733335
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Choline_C5H14NO

814759
type: SpeciesReference
stoichiometry: 1.0
species: 737907

737907
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Ethanolamine_C2H8NO

732695
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Bilirubin_C33H34N4O6

752097
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: tetracosapentaenoyl coenzyme A, n-6_C45H68N7O17P3S

734271
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Creatine_C4H9N3O2

039779
type: Reaction
is: http://identifiers.org/ec-code/1.5.1.2
reactant: 841149
product: 841209
reactant: 841161
product: 841197
notes: R_PRO1x subsystem: Arginine and Proline Metabolism R_PRO1x equation: [c] : nad + pro-L --> 1pyr5c + (2) h + nadh R_PROD2 subsystem: Arginine and Proline Metabolism R_PROD2 equation: [c] : fad + pro-L --> 1pyr5c + fadh2 + h
is: ENSCAFG00000006758.2
product: 841185
fast: false
reactant: 841137
product: 841173
is: http://identifiers.org/ec-code/1.5.99.8
reversible: false

841149
type: SpeciesReference
stoichiometry: 1.0
species: 746978

841209
type: SpeciesReference
stoichiometry: 1.0
species: 747050

841161
type: SpeciesReference
stoichiometry: 2.0
species: 749875

749875
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Proline_C5H9NO2

841197
type: SpeciesReference
stoichiometry: 3.0
species: 741259

841185
type: SpeciesReference
stoichiometry: 2.0
species: 726668

726668
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1-Pyrroline-5-carboxylate_C5H6NO2

841137
type: SpeciesReference
stoichiometry: 1.0
species: 738027

738027
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

841173
type: SpeciesReference
stoichiometry: 1.0
species: 738075

738075
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

739063
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GA2 (homo sapiens)_C38H69N2O17FULLRCO

749827
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Proline_C5H9NO2

731634
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: lysophosphatidic acid (homo sapiens)_C3H6O5PFULLRCO2

032643
type: Reaction
reversible: false
fast: false
product: 774773
product: 774749
reactant: 774737
is: ENSCAFG00000003010.2
name: Ceramide glucosyltransferase
notes: R_UGCG subsystem: Sphingolipid Metabolism R_UGCG equation: [r] : crm_hs + udpg --> gluside_hs + h + udp
is: http://identifiers.org/ec-code/2.4.1.80
reactant: 774725
product: 774761

774773
type: SpeciesReference
stoichiometry: 1.0
species: 740107

740107
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO

774749
type: SpeciesReference
stoichiometry: 1.0
species: 753206

753206
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: UDP_C9H11N2O12P2

774737
type: SpeciesReference
stoichiometry: 1.0
species: 734321

734321
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

774725
type: SpeciesReference
stoichiometry: 1.0
species: 753290

753290
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: UDPglucose_C15H22N2O17P2

774761
type: SpeciesReference
stoichiometry: 1.0
species: 741332

736086
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: dGTP_C10H12N5O13P3

736644
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N,N-Dimethylglycine_C4H9NO2

033754
type: Reaction
product: 783655
product: 783643
is: ENSCAFG00000002852.2
reversible: false
name: electron transfer flavoprotein
notes: R_ETF subsystem: Fatty acid oxidation R_ETF equation: [m] : etfox + fadh2 --> etfrd + fad
reactant: 783631
fast: false
is: ENSCAFG00000018143.2
reactant: 783619

783655
type: SpeciesReference
stoichiometry: 1.0
species: 738039

738039
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

783643
type: SpeciesReference
stoichiometry: 1.0
species: 737895

737895
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Electron transfer flavoprotein reduced_RH2

783631
type: SpeciesReference
stoichiometry: 1.0
species: 738087

783619
type: SpeciesReference
stoichiometry: 1.0
species: 737882

737882
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Electron transfer flavoprotein oxidized_R

728908
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: haxglutamyl folate (DHF)_C44H49N12O21

041226
type: Reaction
fast: false
product: 855617
reactant: 855581
is: http://identifiers.org/ec-code/3.5.1.6
reversible: false
notes: R_BUP2 subsystem: Pyrimidine Catabolism R_BUP2 equation: [c] : 3uib + (2) h + h2o --> 3aib-D + co2 + nh4 R_UPPN subsystem: Pyrimidine Catabolism R_UPPN equation: [c] : cala + (2) h + h2o --> ala-B + co2 + nh4
product: 855629
is: ENSCAFG00000013843.2
reactant: 855557
product: 855593
reactant: 855545
reactant: 855569
product: 855605

855617
type: SpeciesReference
stoichiometry: 1.0
species: 731465

855581
type: SpeciesReference
stoichiometry: 4.0
species: 741259

855629
type: SpeciesReference
stoichiometry: 1.0
species: 727251

727251
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-3-Amino-isobutanoate_C4H9NO2

855557
type: SpeciesReference
stoichiometry: 1.0
species: 727868

727868
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Ureidoisobutyrate_C5H9N2O3

855593
type: SpeciesReference
stoichiometry: 2.0
species: 747294

747294
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Ammonium_H4N

855545
type: SpeciesReference
stoichiometry: 1.0
species: 733021

733021
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Carbamoyl-beta-alanine_C4H7N2O3

855569
type: SpeciesReference
stoichiometry: 2.0
species: 741151

855605
type: SpeciesReference
stoichiometry: 2.0
species: 733981

732780
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Biotinyl-5'-AMP_C20H27N7O9PS

037532
type: Reaction
is: ENSCAFG00000014595.2
product: 819268
product: 819280
reactant: 819208
is: http://identifiers.org/ec-code/2.4.1.1
reactant: 819232
product: 819292
is: ENSCAFG00000004380.2
product: 819256
notes: R_GLPASE2 subsystem: Starch and Sucrose Metabolism R_GLPASE2 equation: [c] : glygn3 + (7) h2o --> Tyr-ggn + (7) glc-D R_GLPASE1 subsystem: Starch and Sucrose Metabolism R_GLPASE1 equation: [c] : glygn2 + (3) pi --> dxtrn + (3) g1p
reactant: 819220
reactant: 819244
is: ENSCAFG00000014281.2
reversible: false
fast: false

819268
type: SpeciesReference
stoichiometry: 1.0
species: 737399

737399
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphorylase-limit dextrin (glycogenin-1,6{4[1,4-Glc], 4[1,4-Glc]})_C48H81O41X

819280
type: SpeciesReference
stoichiometry: 7.0
species: 739815

819208
type: SpeciesReference
stoichiometry: 1.0
species: 740397

740397
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]})_C66H111O56X

819232
type: SpeciesReference
stoichiometry: 3.0
species: 749200

819292
type: SpeciesReference
stoichiometry: 1.0
species: 729883

729883
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Tyr-194 of apo-glycogenin protein (primer for glycogen synthesis)_XOH

819256
type: SpeciesReference
stoichiometry: 3.0
species: 738918

738918
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Glucose 1-phosphate_C6H11O9P

819220
type: SpeciesReference
stoichiometry: 1.0
species: 740421

819244
type: SpeciesReference
stoichiometry: 7.0
species: 741151

727444
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Hydroxypropionyl-CoA_C24H36N7O18P3S

736171
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _3alpha,7alpha-Dihydroxy-5beta-cholestanate_C27H45O4

754207
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Xyl-L-Ser (protein)_C5H9O4X

031993
type: Reaction
is: ENSCAFG00000003922.2
product: 768915
reactant: 768855
reactant: 768879
product: 768891
reversible: true
reactant: 768843
product: 768903
notes: R_PHEtec subsystem: Transport, Extracellular R_PHEtec equation: phe-L[e] <==> phe-L[c] R_TYRt subsystem: Transport, Extracellular R_TYRt equation: tyr-L[e] <==> tyr-L[c] R_TRPt subsystem: Transport, Extracellular R_TRPt equation: trp-L[e] <==> trp-L[c] R_34DHPHEt subsystem: Transport, Extracellular R_34DHPHEt equation: _34dhphe[e] <==> 34dhphe[c]
fast: false
reactant: 768867
product: 768927

768915
type: SpeciesReference
stoichiometry: 1.0
species: 752829

768855
type: SpeciesReference
stoichiometry: 1.0
species: 727154

727154
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _3,4-Dihydroxy-L-phenylalanine_C9H11NO4

768879
type: SpeciesReference
stoichiometry: 1.0
species: 749043

749043
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Phenylalanine_C9H11NO2

768891
type: SpeciesReference
stoichiometry: 1.0
species: 727142

727142
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3,4-Dihydroxy-L-phenylalanine_C9H11NO4

768843
type: SpeciesReference
stoichiometry: 1.0
species: 752842

752842
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Tryptophan_C11H12N2O2

768903
type: SpeciesReference
stoichiometry: 1.0
species: 753072

753072
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Tyrosine_C9H11NO3

768867
type: SpeciesReference
stoichiometry: 1.0
species: 753084

753084
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Tyrosine_C9H11NO3

768927
type: SpeciesReference
stoichiometry: 1.0
species: 749031

749031
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Phenylalanine_C9H11NO2

753651
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: UTP_C9H11N2O15P3

034300
type: Reaction
is: ENSCAFG00000011762.2
is: ENSCAFG00000002077.2
reactant: 788661
name: carboxylic acid dissociation
is: ENSCAFG00000008702.2
fast: false
is: http://identifiers.org/ec-code/4.2.1.1
is: ENSCAFG00000025237.1
product: 788685
is: ENSCAFG00000020399.2
is: ENSCAFG00000008676.2
notes: R_H2CO3D subsystem: Miscellaneous R_H2CO3D equation: [c] : co2 + h2o <==> h2co3
reactant: 788673
reversible: true
is: ENSCAFG00000016990.2

788661
type: SpeciesReference
stoichiometry: 1.0
species: 733981

788685
type: SpeciesReference
stoichiometry: 1.0
species: 741054

788673
type: SpeciesReference
stoichiometry: 1.0
species: 741151

031957
type: Reaction
is: ENSCAFG00000012442.2
reactant: 768636
is: ENSCAFG00000004229.2
reactant: 768648
is: http://identifiers.org/ec-code/1.4.1.4
is: ENSCAFG00000016095.2
product: 768734
is: http://identifiers.org/ec-code/1.4.1.2
product: 768684
product: 768708
reactant: 768672
reactant: 768660
fast: false
notes: R_GLUDxm subsystem: Glutamate metabolism R_GLUDxm equation: [m] : glu-L + h2o + nad <==> akg + h + nadh + nh4 R_GLUDym subsystem: Glutamate metabolism R_GLUDym equation: [m] : glu-L + h2o + nadp <==> akg + h + nadph + nh4
product: 768721
reversible: true
product: 768696

768636
type: SpeciesReference
stoichiometry: 2.0
species: 741199

768648
type: SpeciesReference
stoichiometry: 2.0
species: 740023

740023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Glutamate_C5H8NO4

768734
type: SpeciesReference
stoichiometry: 1.0
species: 747062

768684
type: SpeciesReference
stoichiometry: 2.0
species: 747319

747319
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Ammonium_H4N

768708
type: SpeciesReference
stoichiometry: 1.0
species: 747185

768672
type: SpeciesReference
stoichiometry: 1.0
species: 747123

768660
type: SpeciesReference
stoichiometry: 1.0
species: 747002

768721
type: SpeciesReference
stoichiometry: 2.0
species: 741308

768696
type: SpeciesReference
stoichiometry: 2.0
species: 731429

731429
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _2-Oxoglutarate_C5H4O5

748025
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: octadecadienoate (n-C18:2)_C18H31O2

743348
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 27_C104H169N7O88S4

740277
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Glycerol 3-phosphate_C3H7O6P

750998
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Selenocystathionine_C7H14N2O4Se

729943
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Aminoacetone_C3H8NO

743516
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 3_C233H371N16O205S12

737460
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: epiandrosterone_C19H28O3

728884
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: pentaglutamyl folate (THF)_C39H45N11O18

747026
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

734018
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: CO2_CO2

735685
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: docosa-4,7,10,13,16-pentaenoyl carnitine_C29H47NO4

ORG:
  orgname: University of Missouri - Columbia
n:
  given: Conant
  family: Conant

033863
type: Reaction
product: 784515
notes: R_ADRNLPVESSEC subsystem: Transport, Extracellular R_ADRNLPVESSEC equation: (3) adrnl[c] + (2) atp[c] + (2) h2o[c] --> (2) adp[c] + (3) adrnl[e] + (2) h[c] + (2) pi[c] R_5HTRPVESSEC subsystem: Transport, Extracellular R_5HTRPVESSEC equation: (3) 5htrp[c] + (2) atp[c] + (2) h2o[c] --> (3) 5htrp[e] + (2) adp[c] + (2) h[c] + (2) pi[c] R_NRPPHRVESSEC subsystem: Transport, Extracellular R_NRPPHRVESSEC equation: (2) atp[c] + (2) h2o[c] + (3) nrpphr[c] --> (2) adp[c] + (2) h[c] + (3) nrpphr[e] + (2) pi[c] R_HISTAVESSEC subsystem: Transport, Extracellular R_HISTAVESSEC equation: (2) atp[c] + (2) h2o[c] + (3) hista[c] --> (2) adp[c] + (2) h[c] + (3) hista[e] + (2) pi[c] R_DOPAVESSEC subsystem: Transport, Extracellular R_DOPAVESSEC equation: (2) atp[c] + (3) dopa[c] + (2) h2o[c] --> (2) adp[c] + (3) dopa[e] + (2) h[c] + (2) pi[c]
reactant: 784406
reactant: 784455
reactant: 784479
is: ENSCAFG00000010147.2
reactant: 784443
product: 784551
reactant: 784467
fast: false
product: 784527
reversible: false
reactant: 784430
product: 784539
product: 784563
product: 784503
reactant: 784418
product: 784491
product: 784575
is: ENSCAFG00000011950.2

784515
type: SpeciesReference
stoichiometry: 3.0
species: 736995

784406
type: SpeciesReference
stoichiometry: 3.0
species: 747553

784455
type: SpeciesReference
stoichiometry: 3.0
species: 728728

728728
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Hydroxy-L-tryptophan_C11H12N2O3

784479
type: SpeciesReference
stoichiometry: 10.0
species: 741151

784443
type: SpeciesReference
stoichiometry: 3.0
species: 741777

784551
type: SpeciesReference
stoichiometry: 3.0
species: 747565

784467
type: SpeciesReference
stoichiometry: 3.0
species: 736983

784527
type: SpeciesReference
stoichiometry: 3.0
species: 741790

784430
type: SpeciesReference
stoichiometry: 10.0
species: 732441

784539
type: SpeciesReference
stoichiometry: 10.0
species: 730922

784563
type: SpeciesReference
stoichiometry: 3.0
species: 728740

728740
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _5-Hydroxy-L-tryptophan_C11H12N2O3

784503
type: SpeciesReference
stoichiometry: 3.0
species: 731176

784418
type: SpeciesReference
stoichiometry: 3.0
species: 731164

731164
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Adrenaline_C9H14NO3

784491
type: SpeciesReference
stoichiometry: 10.0
species: 749200

784575
type: SpeciesReference
stoichiometry: 10.0
species: 741259

034034
type: Reaction
reactant: 785693
product: 785741
product: 785717
notes: R_SAMHISTA subsystem: Histidine Metabolism R_SAMHISTA equation: [c] : amet + hista --> ahcys + h + mhista
is: ENSCAFG00000005178.2
name: S-Adenosyl-L-methionine:histamine N-tele-methyltransferase
reactant: 785705
reversible: false
product: 785729
is: http://identifiers.org/ec-code/2.1.1.8
fast: false

785693
type: SpeciesReference
stoichiometry: 1.0
species: 731694

785741
type: SpeciesReference
stoichiometry: 1.0
species: 741259

785717
type: SpeciesReference
stoichiometry: 1.0
species: 731273

785705
type: SpeciesReference
stoichiometry: 1.0
species: 741777

785729
type: SpeciesReference
stoichiometry: 1.0
species: 746376

746376
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Methylhistamine_C6H12N3

732744
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Biocytin_C16H28N4O4S

729465
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: R group 1 Coenzyme A homo sapiens_XCO2C21H31N7O15P3S

737594
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Elaidic carnitine_C25H47NO4

739668
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: GDP_C10H12N5O11P2

731706
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: S-Adenosyl-L-methionine_C15H23N6O5S

032330
type: Reaction
product: 771989
is: http://identifiers.org/ec-code/2.6.1.13
notes: R_ORNTArm subsystem: Urea cycle/amino group metabolism R_ORNTArm equation: [m] : akg + orn <==> glu-L + glu5sa
name: ornithine transaminase reversible (m)
is: ENSCAFG00000012743.2
reactant: 771964
fast: false
product: 771976
reactant: 771952
reversible: true

771989
type: SpeciesReference
stoichiometry: 1.0
species: 739975

739975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Glutamate 5-semialdehyde_C5H9NO3

771964
type: SpeciesReference
stoichiometry: 1.0
species: 731429

771976
type: SpeciesReference
stoichiometry: 1.0
species: 740023

771952
type: SpeciesReference
stoichiometry: 1.0
species: 748230

748230
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Ornithine_C5H13N2O2

748531
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

037206
type: Reaction
reversible: false
product: 815921
product: 815872
reactant: 815798
product: 815933
product: 815909
product: 815884
reactant: 815786
notes: R_PSFLIP subsystem: Transport, Extracellular R_PSFLIP equation: atp[c] + h2o[c] + ps_hs[e] --> adp[c] + h[c] + pi[c] + ps_hs[c] R_PEFLIP subsystem: Transport, Extracellular R_PEFLIP equation: atp[c] + h2o[c] + pe_hs[e] --> adp[c] + h[c] + pe_hs[c] + pi[c] R_PSFLIPm subsystem: Transport, Mitochondrial R_PSFLIPm equation: atp[c] + h2o[c] + ps_hs[c] --> adp[c] + h[c] + pi[c] + ps_hs[m] R_PEFLIPm subsystem: Transport, Mitochondrial R_PEFLIPm equation: atp[c] + h2o[c] + pe_hs[c] --> adp[c] + h[c] + pe_hs[m] + pi[c]
product: 815897
fast: false
reactant: 815847
reactant: 815823
product: 815859
is: ENSCAFG00000005501.2
reactant: 815835
reactant: 815811

815921
type: SpeciesReference
stoichiometry: 4.0
species: 741259

815872
type: SpeciesReference
stoichiometry: 1.0
species: 748873

748873
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2

815798
type: SpeciesReference
stoichiometry: 1.0
species: 748847

815933
type: SpeciesReference
stoichiometry: 1.0
species: 750141

750141
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphatidylserine (homo sapiens)_C6H11NO6PFULLRCO2FULLR2CO2

815909
type: SpeciesReference
stoichiometry: 1.0
species: 750165

750165
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: phosphatidylserine (homo sapiens)_C6H11NO6PFULLRCO2FULLR2CO2

815884
type: SpeciesReference
stoichiometry: 1.0
species: 748847

815786
type: SpeciesReference
stoichiometry: 4.0
species: 732441

815897
type: SpeciesReference
stoichiometry: 4.0
species: 730922

815847
type: SpeciesReference
stoichiometry: 1.0
species: 750141

815823
type: SpeciesReference
stoichiometry: 4.0
species: 741151

815859
type: SpeciesReference
stoichiometry: 4.0
species: 749200

815835
type: SpeciesReference
stoichiometry: 1.0
species: 750153

815811
type: SpeciesReference
stoichiometry: 1.0
species: 748860

748860
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2

037399
type: Reaction
product: 817850
product: 817862
product: 817838
notes: R_TMDK1 subsystem: Nucleotides R_TMDK1 equation: [c] : atp + thymd --> adp + dtmp + h R_DURIK1 subsystem: Nucleotides R_DURIK1 equation: [c] : atp + duri --> adp + dump + h
reversible: false
product: 817874
is: ENSCAFG00000005294.2
reactant: 817802
reactant: 817826
fast: false
reactant: 817814
is: http://identifiers.org/ec-code/2.7.1.21

817850
type: SpeciesReference
stoichiometry: 2.0
species: 730922

817862
type: SpeciesReference
stoichiometry: 1.0
species: 737151

737151
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dTMP_C10H13N2O8P

817838
type: SpeciesReference
stoichiometry: 1.0
species: 737290

737290
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dUMP_C9H11N2O8P

817874
type: SpeciesReference
stoichiometry: 2.0
species: 741259

817802
type: SpeciesReference
stoichiometry: 1.0
species: 737326

737326
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Deoxyuridine_C9H12N2O5

817826
type: SpeciesReference
stoichiometry: 1.0
species: 752533

752533
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Thymidine_C10H14N2O5

817814
type: SpeciesReference
stoichiometry: 2.0
species: 732441

034601
type: Reaction
reversible: true
product: 791931
reactant: 791871
fast: false
reactant: 791883
is: ENSCAFG00000005437.2
product: 791907
notes: R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_DHEASt subsystem: Transport, Extracellular R_DHEASt equation: dheas[e] + hco3[c] <==> dheas[c] + hco3[e]
reactant: 791895
product: 791919

791931
type: SpeciesReference
stoichiometry: 2.0
species: 741428

791871
type: SpeciesReference
stoichiometry: 1.0
species: 736303

736303
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Dehydroepiandrosterone sulfate_C19H27O5S

791883
type: SpeciesReference
stoichiometry: 2.0
species: 741416

791907
type: SpeciesReference
stoichiometry: 1.0
species: 737846

791895
type: SpeciesReference
stoichiometry: 1.0
species: 737858

791919
type: SpeciesReference
stoichiometry: 1.0
species: 736291

736291
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dehydroepiandrosterone sulfate_C19H27O5S

747111
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

733945
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: CMP-N-acetylneuraminate_C20H29N4O16P

031511
type: Reaction
name: hydroxymethylglutaryl-CoA lyase
is: http://identifiers.org/ec-code/4.1.3.4
notes: R_HMGLm subsystem: Cholesterol Metabolism R_HMGLm equation: [m] : hmgcoa --> acac + accoa
reversible: false
is: ENSCAFG00000002341.2
fast: false
product: 763984
reactant: 763972
product: 763996

763984
type: SpeciesReference
stoichiometry: 1.0
species: 730148

763972
type: SpeciesReference
stoichiometry: 1.0
species: 741826

763996
type: SpeciesReference
stoichiometry: 1.0
species: 730052

741705
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Hexacosanoyl-CoA (n-C26:0CoA)_C47H82N7O17P3S

742043
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 14_C57H84N3O62S5

033463
type: Reaction
product: 781601
product: 781553
product: 781626
is: http://identifiers.org/ec-code/3.6.1.9
reactant: 781456
reactant: 781493
reactant: 781505
product: 781589
is: ENSCAFG00000000001.2
reactant: 781517
is: http://identifiers.org/ec-code/2.7.7.18
product: 781565
reactant: 781468
product: 781613
product: 781541
reactant: 781480
notes: R_UDPGP subsystem: Starch and Sucrose Metabolism R_UDPGP equation: [c] : h2o + udpg --> g1p + (2) h + ump R_NNAT subsystem: NAD Metabolism R_NNAT equation: [c] : atp + h + nicrnt --> dnad + ppi R_DNADDP subsystem: NAD Metabolism R_DNADDP equation: [c] : dnad + h2o --> amp + (2) h + nicrnt R_FADDP subsystem: Riboflavin Metabolism R_FADDP equation: [c] : fad + h2o --> amp + fmn + (2) h
fast: false
is: ENSCAFG00000000367.2
product: 781577
reversible: false
reactant: 781529

781601
type: SpeciesReference
stoichiometry: 6.0
species: 741259

781553
type: SpeciesReference
stoichiometry: 1.0
species: 753399

781626
type: SpeciesReference
stoichiometry: 1.0
species: 749466

781456
type: SpeciesReference
stoichiometry: 1.0
species: 738027

781493
type: SpeciesReference
stoichiometry: 1.0
species: 732441

781505
type: SpeciesReference
stoichiometry: 3.0
species: 741151

781589
type: SpeciesReference
stoichiometry: 2.0
species: 731755

781517
type: SpeciesReference
stoichiometry: 1.0
species: 741259

781565
type: SpeciesReference
stoichiometry: 1.0
species: 738918

781468
type: SpeciesReference
stoichiometry: 1.0
species: 747379

747379
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Nicotinate D-ribonucleotide_C11H12NO9P

781613
type: SpeciesReference
stoichiometry: 1.0
species: 736777

736777
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Deamino-NAD+_C21H24N6O15P2

781541
type: SpeciesReference
stoichiometry: 1.0
species: 747379

781480
type: SpeciesReference
stoichiometry: 1.0
species: 753266

781577
type: SpeciesReference
stoichiometry: 1.0
species: 738255

738255
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: FMN_C17H19N4O9P

781529
type: SpeciesReference
stoichiometry: 1.0
species: 736777

037943
type: Reaction
product: 824312
is: ENSCAFG00000024345.1
reactant: 824216
is: ENSCAFG00000009477.2
reactant: 824192
reversible: false
notes: R_GLCAT9g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT9g equation: [g] : hs_pre7 + udpglcur --> h + hs_pre8 + udp R_GLCAT6g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT6g equation: [g] : hs_pre1 + udpglcur --> h + hs_pre2 + udp R_GLCNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT2g equation: [g] : hs_pre2 + uacgam --> h + hs_pre3 + udp R_GLCAT8g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT8g equation: [g] : hs_pre5 + udpglcur --> h + hs_pre6 + udp R_GLCNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT5g equation: [g] : hs_pre8 + uacgam --> h + hs_pre9 + udp R_GLCNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT3g equation: [g] : hs_pre4 + uacgam --> h + hs_pre5 + udp R_GLCAT7g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT7g equation: [g] : hs_pre3 + udpglcur --> h + hs_pre4 + udp R_GLCNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT4g equation: [g] : hs_pre6 + uacgam --> h + hs_pre7 + udp
reactant: 824240
reactant: 824204
product: 824397
product: 824385
reactant: 824228
product: 824348
product: 824360
fast: false
product: 824409
product: 824324
reactant: 824288
product: 824373
product: 824336
reactant: 824276
product: 824421
is: ENSCAFG00000000831.2
reactant: 824300
reactant: 824264
reactant: 824252

824312
type: SpeciesReference
stoichiometry: 1.0
species: 742479

742479
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 9_C87H129N5O69X

824216
type: SpeciesReference
stoichiometry: 1.0
species: 742419

742419
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 4_C51H76N2O42X

824192
type: SpeciesReference
stoichiometry: 1.0
species: 742382

742382
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 1_C31H49NO25X

824240
type: SpeciesReference
stoichiometry: 1.0
species: 742394

742394
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 2_C37H56NO31X

824204
type: SpeciesReference
stoichiometry: 4.0
species: 753121

824397
type: SpeciesReference
stoichiometry: 1.0
species: 742455

742455
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 7_C73H109N4O58X

824385
type: SpeciesReference
stoichiometry: 1.0
species: 742467

824228
type: SpeciesReference
stoichiometry: 4.0
species: 753338

824348
type: SpeciesReference
stoichiometry: 1.0
species: 742419

824360
type: SpeciesReference
stoichiometry: 1.0
species: 742394

824409
type: SpeciesReference
stoichiometry: 1.0
species: 742407

742407
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 3_C45H69N2O36X

824324
type: SpeciesReference
stoichiometry: 8.0
species: 753157

824288
type: SpeciesReference
stoichiometry: 1.0
species: 742407

824373
type: SpeciesReference
stoichiometry: 1.0
species: 742431

742431
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 5_C59H89N3O47X

824336
type: SpeciesReference
stoichiometry: 8.0
species: 741283

824276
type: SpeciesReference
stoichiometry: 1.0
species: 742455

824421
type: SpeciesReference
stoichiometry: 1.0
species: 742443

742443
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 6_C65H96N3O53X

824300
type: SpeciesReference
stoichiometry: 1.0
species: 742443

824264
type: SpeciesReference
stoichiometry: 1.0
species: 742467

824252
type: SpeciesReference
stoichiometry: 1.0
species: 742431

036579
type: Reaction
is: http://identifiers.org/ec-code/6.2.1.4
reactant: 810147
reactant: 810183
reactant: 810135
reactant: 810171
product: 810243
notes: R_SUCOAS1m subsystem: Citric Acid Cycle R_SUCOAS1m equation: [m] : coa + gtp + succ <==> gdp + pi + succoa R_MECOAS1m subsystem: C5-Branched dibasic acid metabolism R_MECOAS1m equation: [m] : coa + gtp + mescon <==> gdp + mescoa + pi R_ITCOAL1m subsystem: C5-Branched dibasic acid metabolism R_ITCOAL1m equation: [m] : coa + gtp + itacon <==> gdp + itaccoa + pi
product: 810207
reversible: true
is: ENSCAFG00000006612.2
reactant: 810159
fast: false
product: 810195
product: 810231
product: 810219

810147
type: SpeciesReference
stoichiometry: 3.0
species: 740994

740994
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: GTP_C10H12N5O14P3

810183
type: SpeciesReference
stoichiometry: 1.0
species: 743012

743012
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Itaconate_C5H4O4

810135
type: SpeciesReference
stoichiometry: 1.0
species: 746279

746279
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Mesaconate_C5H4O4

810171
type: SpeciesReference
stoichiometry: 3.0
species: 734091

810243
type: SpeciesReference
stoichiometry: 3.0
species: 739692

739692
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: GDP_C10H12N5O11P2

810207
type: SpeciesReference
stoichiometry: 1.0
species: 751687

810159
type: SpeciesReference
stoichiometry: 1.0
species: 751651

751651
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Succinate_C4H4O4

810195
type: SpeciesReference
stoichiometry: 1.0
species: 743000

743000
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Itaconyl-CoA_C26H35N7O19P3S

810231
type: SpeciesReference
stoichiometry: 3.0
species: 749249

810219
type: SpeciesReference
stoichiometry: 1.0
species: 746267

746267
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Mesaconyl-CoA_C26H35N7O19P3S

035816
type: Reaction
product: 803122
notes: R_PROt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_PROt4_LPAREN_2_RPAREN_r equation: (2) na1[e] + pro-L[e] <==> (2) na1[c] + pro-L[c]
fast: false
name: Proline transport (sodium symport) (2:1)
is: ENSCAFG00000018203.2
reactant: 803098
product: 803110
reversible: true
reactant: 803086

803122
type: SpeciesReference
stoichiometry: 1.0
species: 749875

803098
type: SpeciesReference
stoichiometry: 1.0
species: 749887

749887
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Proline_C5H9NO2

803110
type: SpeciesReference
stoichiometry: 2.0
species: 746918

803086
type: SpeciesReference
stoichiometry: 2.0
species: 746930

744169
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked), degradation product 7_C44H73N4O30X

732044
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Adenosine 5'-phosphosulfate_C10H12N5O10PS

030693
type: Reaction
reactant: 756557
product: 756617
fast: false
product: 756605
reactant: 756593
product: 756641
reactant: 756545
product: 756629
notes: R_TCHOLAt2 subsystem: Transport, Extracellular R_TCHOLAt2 equation: (2) na1[e] + tchola[e] --> (2) na1[c] + tchola[c] R_ESTRONESt2 subsystem: Transport, Extracellular R_ESTRONESt2 equation: estrones[e] + (2) na1[e] --> estrones[c] + (2) na1[c] R_CHOLATEt2 subsystem: Transport, Extracellular R_CHOLATEt2 equation: cholate[e] + (2) na1[e] --> cholate[c] + (2) na1[c] R_GCHOLAt2 subsystem: Transport, Extracellular R_GCHOLAt2 equation: gchola[e] + (2) na1[e] --> gchola[c] + (2) na1[c]
is: ENSCAFG00000016597.2
reversible: false
reactant: 756569
product: 756653
reactant: 756581

756557
type: SpeciesReference
stoichiometry: 1.0
species: 739522

756617
type: SpeciesReference
stoichiometry: 1.0
species: 733407

733407
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Cholate_C24H39O5

756605
type: SpeciesReference
stoichiometry: 1.0
species: 737846

756593
type: SpeciesReference
stoichiometry: 1.0
species: 733419

733419
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Cholate_C24H39O5

756641
type: SpeciesReference
stoichiometry: 1.0
species: 739510

739510
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: glycocholate_C26H43NO6

756545
type: SpeciesReference
stoichiometry: 1.0
species: 751856

756629
type: SpeciesReference
stoichiometry: 1.0
species: 751844

751844
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: taurocholic acid_C26H45NO7S

756569
type: SpeciesReference
stoichiometry: 8.0
species: 746930

756653
type: SpeciesReference
stoichiometry: 8.0
species: 746918

756581
type: SpeciesReference
stoichiometry: 1.0
species: 737858

040549
type: Reaction
product: 849356
reactant: 849091
reactant: 849152
reactant: 848909
reactant: 848885
reactant: 849140
reactant: 848727
reactant: 849176
fast: false
product: 849466
reactant: 848619
reactant: 848715
reactant: 849164
product: 849405
reactant: 849103
reactant: 848922
reactant: 848775
product: 849454
reactant: 848799
reactant: 849031
is: ENSCAFG00000017708.2
reactant: 848982
reactant: 848897
reactant: 848607
reactant: 848691
reactant: 848970
product: 849284
product: 849248
reactant: 848958
product: 849562
reactant: 848703
product: 849296
product: 849538
reactant: 848763
reactant: 848787
product: 849368
reactant: 848751
reactant: 848946
reactant: 849019
product: 849478
product: 849441
product: 849260
reactant: 848679
reactant: 848824
product: 849224
reactant: 848934
reactant: 849212
product: 849417
reactant: 848643
reactant: 849007
is: ENSCAFG00000008292.2
reactant: 849079
notes: R_AHEXASEly subsystem: N-Glycan Degradation R_AHEXASEly equation: [l] : (2) h2o + n2m2mn --> (2) acgam + m2mn R_NACHEX4ly subsystem: Chondroitin sulfate degradation R_NACHEX4ly equation: [l] : cs_c_deg1 + h2o --> acgal + cs_c_deg2 R_NACHEX14ly subsystem: Keratan sulfate degradation R_NACHEX14ly equation: [l] : h2o + ksi_deg19 --> acgam + ksi_deg20 R_NACHEXA13ly subsystem: Keratan sulfate degradation R_NACHEXA13ly equation: [l] : (2) h2o + ksi_deg18 --> acgam + h + ksi_deg20 + so4 R_NACHEX20ly subsystem: Keratan sulfate degradation R_NACHEX20ly equation: [l] : h2o + ksi_deg37 --> acgam + ksi_deg38 R_NACHEXA2ly subsystem: Chondroitin sulfate degradation R_NACHEXA2ly equation: [l] : cs_b + (2) h2o --> acgal + cs_b_deg2 + h + so4 R_NACHEX19ly subsystem: Keratan sulfate degradation R_NACHEX19ly equation: [l] : h2o + ksi_deg34 --> acgam + ksi_deg35 R_NACHEXA18ly subsystem: Keratan sulfate degradation R_NACHEXA18ly equation: [l] : (2) h2o + ksi_deg33 --> acgam + h + ksi_deg35 + so4 R_NACHEX21ly subsystem: Keratan sulfate degradation R_NACHEX21ly equation: [l] : h2o + ksi_deg39 --> acgam + ksi_deg40 R_NACHEXA22ly subsystem: Keratan sulfate degradation R_NACHEXA22ly equation: [l] : (3) h2o + ksii_core4_deg3 --> (2) acgam + h + ksii_core2_deg5 + so4 R_NACHEX23ly subsystem: Keratan sulfate degradation R_NACHEX23ly equation: [l] : h2o + ksii_core2_deg4 --> acgam + ksii_core2_deg5 R_NACHEX10ly subsystem: Keratan sulfate degradation R_NACHEX10ly equation: [l] : (2) h2o + ksi_deg7 --> (2) acgam + ksi_deg8 R_NACHEX5ly subsystem: Chondroitin sulfate degradation R_NACHEX5ly equation: [l] : cs_c_deg4 + h2o --> acgal + cs_c_deg5 R_NACHEX2ly subsystem: Chondroitin sulfate degradation R_NACHEX2ly equation: [l] : cs_a_deg4 + h2o --> acgal + cs_a_deg5 R_NACHEXA14ly subsystem: Keratan sulfate degradation R_NACHEXA14ly equation: [l] : (2) h2o + ksi_deg21 --> acgam + h + ksi_deg23 + so4 R_NACHEXA17ly subsystem: Keratan sulfate degradation R_NACHEXA17ly equation: [l] : (2) h2o + ksi_deg30 --> …
product: 849429
reactant: 848667
product: 849514
reactant: 849200
is: http://identifiers.org/ec-code/3.2.1.52
product: 849332
product: 849380
product: 849344
product: 849502
product: 849574
product: 849393
product: 849320
reactant: 848631
product: 849490
reactant: 849067
reversible: false
reactant: 848655
reactant: 848873
product: 849308
reactant: 848995
reactant: 849055
reactant: 848861
reactant: 848849
product: 849272
reactant: 848595
product: 849236

849356
type: SpeciesReference
stoichiometry: 2.0
species: 743264

743264
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 20_C138H223N9O119S6

849091
type: SpeciesReference
stoichiometry: 1.0
species: 744169

849152
type: SpeciesReference
stoichiometry: 1.0
species: 743276

743276
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 21_C132H213N9O114S6

848909
type: SpeciesReference
stoichiometry: 1.0
species: 744386

744386
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 4-linked), degradation product 4_C66H108N6O48SX

848885
type: SpeciesReference
stoichiometry: 1.0
species: 743192

743192
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 16_C160H258N11O137S7

849140
type: SpeciesReference
stoichiometry: 1.0
species: 741356

741356
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: hyaluronan degradation product 1_C22H33N2O16

848727
type: SpeciesReference
stoichiometry: 1.0
species: 744374

744374
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 4-linked), degradation product 3_C66H107N6O51S2X

849176
type: SpeciesReference
stoichiometry: 1.0
species: 743228

743228
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 19_C146H236N10O124S6

849466
type: SpeciesReference
stoichiometry: 2.0
species: 743492

743492
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 38_C54H91N3O41

848619
type: SpeciesReference
stoichiometry: 1.0
species: 743156

743156
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 13_C174H280N12O150S8

848715
type: SpeciesReference
stoichiometry: 1.0
species: 743588

743588
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 7_C210H337N15O181S10

849164
type: SpeciesReference
stoichiometry: 1.0
species: 743432

743432
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 33_C76H125N5O62S2

849405
type: SpeciesReference
stoichiometry: 4.0
species: 744145

744145
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked), degradation product 5_C50H82N4O38SX

849103
type: SpeciesReference
stoichiometry: 1.0
species: 743348

848922
type: SpeciesReference
stoichiometry: 1.0
species: 743144

743144
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 12_C174H279N12O153S9

848775
type: SpeciesReference
stoichiometry: 1.0
species: 734804

734804
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 4_C31H47NO35S3

849454
type: SpeciesReference
stoichiometry: 2.0
species: 743336

743336
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 26_C110H179N7O93S4

848799
type: SpeciesReference
stoichiometry: 1.0
species: 743540

743540
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 41_C34H58N2O26

849031
type: SpeciesReference
stoichiometry: 1.0
species: 743480

743480
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 37_C62H104N4O46

848982
type: SpeciesReference
stoichiometry: 1.0
species: 743468

743468
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 36_C62H103N4O49S1

848897
type: SpeciesReference
stoichiometry: 1.0
species: 744133

744133
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked), degradation product 4_C58H95N5O43SX

848607
type: SpeciesReference
stoichiometry: 1.0
species: 734695

734695
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 3_C31H48NO32S2

848691
type: SpeciesReference
stoichiometry: 1.0
species: 743288

743288
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 22_C132H214N9O111S5

848970
type: SpeciesReference
stoichiometry: 1.0
species: 743612

743612
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 9_C188H301N13O166S10

849284
type: SpeciesReference
stoichiometry: 1.0
species: 743528

743528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 40_C40H68N2O31

849248
type: SpeciesReference
stoichiometry: 2.0
species: 743420

743420
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 32_C82H135N5O67S2

848958
type: SpeciesReference
stoichiometry: 1.0
species: 734915

734915
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 2_C45H66N2O49S4

849562
type: SpeciesReference
stoichiometry: 2.0
species: 734927

734927
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 3_C37H53NO44S4

848703
type: SpeciesReference
stoichiometry: 1.0
species: 743360

743360
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 28_C104H170N7O85S3

849296
type: SpeciesReference
stoichiometry: 24.0
species: 751227

849538
type: SpeciesReference
stoichiometry: 41.0
species: 730427

730427
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: N-Acetyl-D-glucosamine_C8H15NO6

848763
type: SpeciesReference
stoichiometry: 1.0
species: 744193

744193
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked), degradation product 9_C30H50N3O20X

848787
type: SpeciesReference
stoichiometry: 1.0
species: 743444

743444
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 34_C76H126N5O59S1

849368
type: SpeciesReference
stoichiometry: 2.0
species: 734828

734828
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 6_C23H35O27S2

848751
type: SpeciesReference
stoichiometry: 1.0
species: 734670

734670
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 1_C45H68N2O43S2

848946
type: SpeciesReference
stoichiometry: 82.0
species: 741187

849019
type: SpeciesReference
stoichiometry: 1.0
species: 734731

734731
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate C (GalNAc6S-GlcA), free chain_C45H67N2O46S3

849478
type: SpeciesReference
stoichiometry: 3.0
species: 745507

745507
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: (alpha-D-mannosyl)2-beta-D-mannosyl-N-acetylglucosamine_C26H45NO21

849441
type: SpeciesReference
stoichiometry: 2.0
species: 743168

849260
type: SpeciesReference
stoichiometry: 1.0
species: 741404

741404
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: hyaluronan biosynthesis, precursor 1_C14H20NO11

848679
type: SpeciesReference
stoichiometry: 1.0
species: 734585

734585
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), degradation product 1_C45H67N2O46S3

848824
type: SpeciesReference
stoichiometry: 1.0
species: 743312

743312
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 24_C118H191N8O101S5

849224
type: SpeciesReference
stoichiometry: 2.0
species: 734525

734525
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 2_C37H55NO38S2

848934
type: SpeciesReference
stoichiometry: 1.0
species: 734816

734816
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 5_C31H48NO32S2

849212
type: SpeciesReference
stoichiometry: 1.0
species: 743576

743576
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 6_C210H336N15O184S11

849417
type: SpeciesReference
stoichiometry: 2.0
species: 734598

734598
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), degradation product 2_C37H54NO41S3

848643
type: SpeciesReference
stoichiometry: 1.0
species: 734963

734963
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 6_C31H48NO32S2

849007
type: SpeciesReference
stoichiometry: 1.0
species: 743180

743180
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 15_C160H257N11O140S8

849079
type: SpeciesReference
stoichiometry: 1.0
species: 744121

744121
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked), degradation product 3_C58H94N5O46S2X

849429
type: SpeciesReference
stoichiometry: 2.0
species: 743600

743600
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 8_C194H311N13O171S10

848667
type: SpeciesReference
stoichiometry: 1.0
species: 734841

734841
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), free chain_C45H65N2O52S5

849514
type: SpeciesReference
stoichiometry: 2.0
species: 734975

734975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 7_C23H35O27S2

849200
type: SpeciesReference
stoichiometry: 1.0
species: 734513

734513
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 1_C45H68N2O43S2

849332
type: SpeciesReference
stoichiometry: 24.0
species: 741296

849380
type: SpeciesReference
stoichiometry: 2.0
species: 743300

743300
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 23_C124H201N8O106S5

849344
type: SpeciesReference
stoichiometry: 2.0
species: 734779

734779
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 2_C37H53NO44S4

849502
type: SpeciesReference
stoichiometry: 2.0
species: 743456

743456
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 35_C68H113N4O54S1

849574
type: SpeciesReference
stoichiometry: 2.0
species: 734683

734683
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 2_C37H55NO38S2

849393
type: SpeciesReference
stoichiometry: 2.0
species: 743204

743204
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 17_C152H245N10O132S7

849320
type: SpeciesReference
stoichiometry: 2.0
species: 743372

743372
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 29_C96H157N6O80S3

848631
type: SpeciesReference
stoichiometry: 1.0
species: 734573

734573
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate A (GalNAc4S-GlcA), free chain_C45H67N2O46S3

849490
type: SpeciesReference
stoichiometry: 2.0
species: 734719

734719
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 5_C23H36O24S

849067
type: SpeciesReference
stoichiometry: 1.0
species: 734767

734767
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 1_C45H66N2O49S4

848655
type: SpeciesReference
stoichiometry: 1.0
species: 734939

734939
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 4_C31H46NO38S4

848873
type: SpeciesReference
stoichiometry: 1.0
species: 734622

734622
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), free chain_C45H66N2O49S4

849308
type: SpeciesReference
stoichiometry: 2.0
species: 744181

744181
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked), degradation product 8_C36H60N3O25X

848995
type: SpeciesReference
stoichiometry: 1.0
species: 734987

734987
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), free chain_C45H64N2O55S6

849055
type: SpeciesReference
stoichiometry: 1.0
species: 734707

848861
type: SpeciesReference
stoichiometry: 1.0
species: 743408

743408
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 31_C90H148N6O72S2

848849
type: SpeciesReference
stoichiometry: 1.0
species: 743504

743504
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 39_C48H81N3O36

849272
type: SpeciesReference
stoichiometry: 17.0
species: 730307

730307
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: N-Acetyl-D-galactosamine_C8H15NO6

848595
type: SpeciesReference
stoichiometry: 1.0
species: 734549

734549
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 4_C31H49NO29S

849236
type: SpeciesReference
stoichiometry: 1.0
species: 737967

737967
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: F1alpha_C22H37N2O15X

849550
type: SpeciesReference
stoichiometry: 2.0
species: 743132

743132
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 11_C180H289N12O158S9

848739
type: SpeciesReference
stoichiometry: 1.0
species: 743216

743216
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 18_C146H235N10O127S7

849188
type: SpeciesReference
stoichiometry: 1.0
species: 746786

746786
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: de-Fuc, reducing GlcNAc removed, de-Sia, de-Gal form of PA6 (w/o peptide linkage)_C42H71N3O31

849127
type: SpeciesReference
stoichiometry: 1.0
species: 743396

849043
type: SpeciesReference
stoichiometry: 1.0
species: 746858

746858
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: reducing GlcNAc removed form of n2m2nmasn (w/o peptide)_C50H84N4O36

849526
type: SpeciesReference
stoichiometry: 1.0
species: 734561

734561
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 5_C23H36O24S

848837
type: SpeciesReference
stoichiometry: 1.0
species: 744157

744157
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked), degradation product 6_C44H72N4O33SX

849115
type: SpeciesReference
stoichiometry: 1.0
species: 743324

743324
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 25_C118H192N8O98S4

848811
type: SpeciesReference
stoichiometry: 1.0
species: 743120

743120
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 10_C188H302N13O163S9

733250
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: CDP diacylglycerol (homo sapiens)_C12H17N3O11P2FULLRCO2FULLR2CO2

748711
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

034144
type: Reaction
modifier: 787482
modifier: 787374
modifier: 787146
modifier: 787506
modifier: 787470
modifier: 787134
product: 786774
modifier: 787038
modifier: 787122
reactant: 786750
modifier: 787026
modifier: 786846
modifier: 787110
modifier: 787098
modifier: 787326
modifier: 787182
fast: false
product: 786810
modifier: 787086
product: 786834
modifier: 787314
modifier: 787338
modifier: 787170
modifier: 787074
is: ENSCAFG00000007662.2
modifier: 787410
modifier: 787302
modifier: 787062
modifier: 787278
modifier: 787362
modifier: 787266
modifier: 786894
product: 786786
modifier: 787350
is: http://identifiers.org/ec-code/6.2.1.3
modifier: 787254
modifier: 786990
modifier: 787242
modifier: 787014
modifier: 786918
modifier: 787158
modifier: 787002
reversible: false
modifier: 786906
reactant: 786725
reactant: 786713
modifier: 786978
reactant: 786762
modifier: 787290
modifier: 786966
modifier: 786858
modifier: 787458
modifier: 787050
modifier: 787218
modifier: 786954
modifier: 786930
modifier: 787446
modifier: 787194
modifier: 787206
modifier: 786942
modifier: 787434
reactant: 786701
product: 786798
product: 786822
modifier: 787422
modifier: 786882
modifier: 787398
modifier: 786870
modifier: 787494
modifier: 787386
reactant: 786738
modifier: 787230
notes: R_FACOAL2252 subsystem: Fatty acid activation R_FACOAL2252 equation: [c] : atp + clpnd + coa <==> amp + clpndcoa + ppi R_FACOAL226 subsystem: Fatty acid activation R_FACOAL226 equation: [c] : atp + coa + crvnc <==> amp + c226coa + ppi R_FACOAL1812 subsystem: Fatty acid activation R_FACOAL1812 equation: [c] : atp + coa + vacc <==> amp + ppi + vacccoa R_FACOAL161 subsystem: Fatty acid activation R_FACOAL161 equation: [c] : atp + coa + hdcea <==> amp + hdcoa + ppi R_FACOAL2251 subsystem: Fatty acid activation R_FACOAL2251 equation: [c] : atp + coa + dcsptn1 <==> amp + dcsptn1coa + ppi R_FACOAL180i subsystem: Fatty acid activation R_FACOAL180i equation: [c] : atp + coa + ocdca --> amp + ppi + stcoa R_FACOAL260 subsystem: Fatty acid activation R_FACOAL260 equation: [c] : atp + coa + hexc <==> amp + hexccoa + ppi R_FACOAL241 subsystem: Fatty acid activation R_FACOAL241 equation: [c] : atp + coa + nrvnc <==> amp + nrvnccoa + ppi R_FACOAL181i subsystem: Fatty acid activation R_FACOAL181i equation: [c] : atp + coa + ocdcea --> amp + odecoa + ppi R_FACOAL245_2 subsystem: Fatty acid activation R_FACOAL245_2 equation: [c] : atp + coa + tetpent3 <==> amp + ppi + tetpent3coa R_FACOAL245_1 subsystem: Fatty acid activation R_FACOAL245_1 equation: [c] : atp + coa + tetpent6 <==> amp + ppi + tetpent6coa R_FACOAL2042 subsystem: Fatty acid activation R_FACOAL2042 equation: [c] : atp + coa + eicostet <==> amp + eicostetcoa + ppi R_FACOAL224 subsystem: Fatty acid activation R_FACOAL224 equation: [c] : adrn + atp + coa <==> adrncoa + amp + ppi R_FACOAL246_1 subsystem: Fatty acid activation R_FACOAL246_1 equation: [c] : atp + coa + tethex3 <==> amp + ppi + tethex3coa R_FACOAL204 subsystem: Fatty acid activation R_FACOAL204 equation: [c] : arachd + atp + coa <==> amp + arachdcoa + ppi R_FACOAL1831 subsystem: Fatty acid activation R_FACOAL1831 equation: [c] : atp + coa + lnlncg <==> amp + lnlncgcoa + ppi R_FACOAL203 subsystem: Fatty acid activation R_FACOAL203 equation: [c] : atp + coa + dln…

753688
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: vaccenic acid_C18H33O2

732068
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Arachidic acid_C20H39O2

745085
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: linoelaidyl coenzyme A_C39H62N7O17P3S

745073
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: linoelaidic acid (all trans C18:2)_C18H31O2

786774
type: SpeciesReference
stoichiometry: 1.0
species: 732188

732188
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: C20:4-CoA_C41H62N7O17P3S

750189
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: pentadecanoate_C15H29O2

731102
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: adrenyl coenzyme A_C43H66N7O17P3S

786750
type: SpeciesReference
stoichiometry: 1.0
species: 747963

747963
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: octadecanoate (n-C18:0)_C18H35O2

745146
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: linoleic coenzyme A_C39H62N7O17P3S

751977
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosahexaenoyl coenzyme A_C45H66N7O17P3S

752001
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosapentaenoic acid, n-3_C24H37O2

745206
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: alpha-Linolenoyl-CoA_C39H60N7O17P3S

737520
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: eicosatetranoic acid_C20H31O2

737581
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: elaidic acid_C18H33O2

786810
type: SpeciesReference
stoichiometry: 1.0
species: 751470

741669
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: hexacosanoate (n-C26:0)_C26H51O2

786834
type: SpeciesReference
stoichiometry: 4.0
species: 749466

733786
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: clupanodonyl CoA_C43H64N7O17P3S

736571
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dihomo-gamma-linolenic acid (n-6)_C20H33O2

741524
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Hexadecenoate (n-C16:1)_C16H29O2

752085
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosapentaenoyl coenzyme A, n-6_C45H68N7O17P3S

741923
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: heptadecanoyl coa_C38H64N7O17P3S

752642
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: timnodonyl coenzyme A_C41H60N7O17P3S

737533
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: eicosatetranoyl coenzyme A_C41H62N7O17P3S

752073
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosapentaenoic acid, n-6_C24H37O2

745134
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: linoleic acid (all cis C18:2) n-6_C18H31O2

752013
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosapentaenoyl coenzyme A, n-3_C45H68N7O17P3S

786786
type: SpeciesReference
stoichiometry: 1.0
species: 748085

748085
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Octadecenoyl-CoA (n-C18:1CoA)_C39H64N7O17P3S

744952
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: lignocericyl coenzyme A_C45H78N7O17P3S

735637
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: docosa-4,7,10,13,16-pentaenoic acid (n-6)_C22H33O2

741560
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Hexadecenoyl-CoA (n-C16:1CoA)_C37H60N7O17P3S

750201
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: pentadecanoyl Coenzyme A_C36H60N7O17P3S

748061
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053

786725
type: SpeciesReference
stoichiometry: 1.0
species: 732152

732152
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: arachidonic acid_C20H31O2

786713
type: SpeciesReference
stoichiometry: 4.0
species: 734054

732913
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cervonyl coenzyme A_C43H62N7O17P3S

786762
type: SpeciesReference
stoichiometry: 1.0
species: 747987

747987
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: octadecenoate (n-C18:1)_C18H33O2

735649
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: docosa-4,7,10,13,16-pentaenoyl coenzyme A_C43H64N7O17P3S

752145
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosatetraenoic acid n-6_C24H39O2

751554
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: stearidonic acid C18:4, n-3_C18H27O2

751566
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: stearidonyl coenzyme A_C39H58N7O17P3S

731066
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: adrenic acid_C22H35O2

741681
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Hexacosanoyl-CoA (n-C26:0CoA)_C47H82N7O17P3S

732092
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: arachidyl coenzyme A_C41H70N7O17P3S

752630
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: timnodonic acid C20:5, n-3_C20H29O2

734441
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cervonic acid, C22:6 n-3_C22H31O2

786701
type: SpeciesReference
stoichiometry: 1.0
species: 741476

786798
type: SpeciesReference
stoichiometry: 1.0
species: 749297

786822
type: SpeciesReference
stoichiometry: 4.0
species: 731755

745194
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: alpha-Linolenic acid, C18:3, n-3_C18H29O2

745254
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: gamma-linolenic acid_C18H29O2

733774
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: clupanodonic acid_C22H33O2

751965
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosahexaenoic acid, n-3_C24H35O2

786738
type: SpeciesReference
stoichiometry: 4.0
species: 732441

741911
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: heptadecanoate_C17H33O2

726392
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _12-Hydroperoxyeicosa-5,8,10,14-tetraenoate_C20H31O4

036179
type: Reaction
fast: false
product: 807135
notes: R_NAt3_1g subsystem: Transport, Golgi Apparatus R_NAt3_1g equation: h[g] + na1[c] <==> h[c] + na1[g] R_Kt3g subsystem: Transport, Golgi Apparatus R_Kt3g equation: h[g] + k[c] <==> h[c] + k[g]
reactant: 807098
product: 807159
reactant: 807123
reactant: 807110
is: ENSCAFG00000014767.2
is: ENSCAFG00000011460.2
reversible: true
product: 807147

807135
type: SpeciesReference
stoichiometry: 1.0
species: 743096

743096
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: potassium_K

807098
type: SpeciesReference
stoichiometry: 1.0
species: 743072

743072
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: potassium_K

807159
type: SpeciesReference
stoichiometry: 2.0
species: 741259

807123
type: SpeciesReference
stoichiometry: 1.0
species: 746918

807110
type: SpeciesReference
stoichiometry: 2.0
species: 741283

807147
type: SpeciesReference
stoichiometry: 1.0
species: 746942

746942
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Sodium_Na

038948
type: Reaction
is: ENSCAFG00000006838.2
notes: R_PPAP subsystem: Triacylglycerol Synthesis R_PPAP equation: [c] : h2o + pa_hs --> dag_hs + pi
fast: false
name: phosphatidic acid phosphatase
reversible: false
reactant: 832761
is: ENSCAFG00000023430.1
is: ENSCAFG00000019734.2
product: 832773
is: ENSCAFG00000018964.2
is: http://identifiers.org/ec-code/3.1.3.4
reactant: 832749
product: 832785

832761
type: SpeciesReference
stoichiometry: 1.0
species: 741151

832773
type: SpeciesReference
stoichiometry: 1.0
species: 735409

832749
type: SpeciesReference
stoichiometry: 1.0
species: 748302

748302
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

832785
type: SpeciesReference
stoichiometry: 1.0
species: 749200

036724
type: Reaction
product: 811240
reactant: 811204
notes: R_GLCNACPT_U subsystem: N-Glycan Biosynthesis R_GLCNACPT_U equation: [c] : (0.1) dolp_U + uacgam --> (0.1) naglc2p_U + ump R_GLCNACPT_L subsystem: N-Glycan Biosynthesis R_GLCNACPT_L equation: [c] : (0.1) dolp_L + uacgam --> (0.1) naglc2p_L + ump
product: 811216
fast: false
reversible: false
is: http://identifiers.org/ec-code/2.7.8.15
product: 811228
reactant: 811180
is: ENSCAFG00000012302.2
reactant: 811192

811240
type: SpeciesReference
stoichiometry: 1.0
species: 747233

747233
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Acetyl-D-glucosaminyldiphosphodolichol, human liver homolog_C1160H1898N10O120P20

811204
type: SpeciesReference
stoichiometry: 2.0
species: 753109

811216
type: SpeciesReference
stoichiometry: 1.0
species: 747245

747245
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Acetyl-D-glucosaminyldiphosphodolichol, human uterine homolog_C1105H1810N10O120P20

811228
type: SpeciesReference
stoichiometry: 2.0
species: 753399

811180
type: SpeciesReference
stoichiometry: 1.0
species: 736934

736934
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dolichol phosphate, human liver homolog_C1080H1758O40P10

811192
type: SpeciesReference
stoichiometry: 1.0
species: 736959

036591
type: Reaction
name: UTP-glucose-1-phosphate uridylyltransferase
product: 810291
notes: R_GALU subsystem: Galactose metabolism R_GALU equation: [c] : g1p + h + utp <==> ppi + udpg
fast: false
is: http://identifiers.org/ec-code/2.7.7.9
reactant: 810279
is: ENSCAFG00000003137.2
reactant: 810255
product: 810303
reversible: true
reactant: 810267

810291
type: SpeciesReference
stoichiometry: 1.0
species: 753266

810279
type: SpeciesReference
stoichiometry: 1.0
species: 753639

753639
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: UTP_C9H11N2O15P3

810255
type: SpeciesReference
stoichiometry: 1.0
species: 738918

810303
type: SpeciesReference
stoichiometry: 1.0
species: 749466

810267
type: SpeciesReference
stoichiometry: 1.0
species: 741259

731018
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: ADPribose 2'-phosphate_C15H20N5O17P3

735757
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Deoxycytidine_C9H13N3O4

729429
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Histone N6-methyl-L-lysine_CXH4

035359
type: Reaction
product: 799871
product: 799907
reactant: 799859
product: 799895
reactant: 799810
reactant: 799847
reactant: 799786
fast: false
is: ENSCAFG00000003532.2
product: 799919
product: 799943
reversible: false
product: 799883
reactant: 799798
reactant: 799834
is: http://identifiers.org/ec-code/1.5.1.8
notes: R_SACCD3m subsystem: Lysine Metabolism R_SACCD3m equation: [m] : akg + h + lys-L + nadph --> h2o + nadp + saccrp-L R_SACCD4m subsystem: Lysine Metabolism R_SACCD4m equation: [m] : h2o + nadp + saccrp-L --> L2aadp6sa + glu-L + h + nadph
reactant: 799822
product: 799931
is: http://identifiers.org/ec-code/1.5.1.10

799871
type: SpeciesReference
stoichiometry: 1.0
species: 741199

799907
type: SpeciesReference
stoichiometry: 1.0
species: 740023

799859
type: SpeciesReference
stoichiometry: 1.0
species: 741308

799895
type: SpeciesReference
stoichiometry: 1.0
species: 729258

729258
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-2-Aminoadipate 6-semialdehyde_C6H11NO3

799810
type: SpeciesReference
stoichiometry: 1.0
species: 745423

799847
type: SpeciesReference
stoichiometry: 1.0
species: 747185

799786
type: SpeciesReference
stoichiometry: 1.0
species: 741199

799919
type: SpeciesReference
stoichiometry: 1.0
species: 747123

799943
type: SpeciesReference
stoichiometry: 1.0
species: 741308

799883
type: SpeciesReference
stoichiometry: 1.0
species: 750854

750854
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Saccharopine_C11H19N2O6

799798
type: SpeciesReference
stoichiometry: 1.0
species: 750854

799834
type: SpeciesReference
stoichiometry: 1.0
species: 747123

799822
type: SpeciesReference
stoichiometry: 1.0
species: 731429

799931
type: SpeciesReference
stoichiometry: 1.0
species: 747185

735216
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Cysteine_C3H7NO2S

737055
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Deoxyribose_C5H10O4

740898
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Oxidized glutathione_C20H30N6O12S2

038960
type: Reaction
reactant: 832797
reactant: 832809
reversible: false
reactant: 832821
product: 832833
notes: R_FMNAT subsystem: Riboflavin Metabolism R_FMNAT equation: [c] : atp + fmn + h --> fad + ppi
name: FMN adenylyltransferase
fast: false
is: ENSCAFG00000017129.2
product: 832845
is: http://identifiers.org/ec-code/2.7.7.2

832797
type: SpeciesReference
stoichiometry: 1.0
species: 732441

832809
type: SpeciesReference
stoichiometry: 1.0
species: 738255

832821
type: SpeciesReference
stoichiometry: 1.0
species: 741259

832833
type: SpeciesReference
stoichiometry: 1.0
species: 738027

832845
type: SpeciesReference
stoichiometry: 1.0
species: 749466

745327
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Lipoamide_C8H15NOS2

742309
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 10_C79H121N5O77S4X

040827
type: Reaction
product: 852616
reactant: 852580
product: 852640
product: 852628
reversible: false
reactant: 852592
notes: R_2OXOADOXm subsystem: Lysine Metabolism R_2OXOADOXm equation: [m] : 2oxoadp + coa + nad --> co2 + glutcoa + nadh R_AKGDm subsystem: Citric Acid Cycle R_AKGDm equation: [m] : akg + coa + nad --> co2 + nadh + succoa
reactant: 852568
product: 852652
fast: false
is: ENSCAFG00000016989.2
reactant: 852604
is: http://identifiers.org/ec-code/1.2.4.2

852616
type: SpeciesReference
stoichiometry: 1.0
species: 751687

852580
type: SpeciesReference
stoichiometry: 2.0
species: 734091

852640
type: SpeciesReference
stoichiometry: 1.0
species: 740120

740120
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Glutaryl-CoA_C26H37N7O19P3S

852628
type: SpeciesReference
stoichiometry: 2.0
species: 734005

852592
type: SpeciesReference
stoichiometry: 1.0
species: 731429

852568
type: SpeciesReference
stoichiometry: 1.0
species: 727034

727034
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _2-Oxoadipate_C6H6O5

852652
type: SpeciesReference
stoichiometry: 2.0
species: 747062

852604
type: SpeciesReference
stoichiometry: 2.0
species: 747002

030489
type: Reaction
is: http://identifiers.org/ec-code/3.6.1.5
reactant: 755249
reactant: 755237
is: ENSCAFG00000005128.1
product: 755285
fast: false
is: ENSCAFG00000019522.1
reactant: 755225
product: 755261
is: ENSCAFG00000019892.2
is: ENSCAFG00000004371.2
is: ENSCAFG00000025238.1
reversible: false
product: 755273
notes: R_ATPH2e subsystem: Nucleotides R_ATPH2e equation: [e] : adp + h2o --> amp + h + pi R_ATPH1e subsystem: Nucleotides R_ATPH1e equation: [e] : atp + (2) h2o --> amp + (2) h + (2) pi

755249
type: SpeciesReference
stoichiometry: 3.0
species: 741163

755237
type: SpeciesReference
stoichiometry: 1.0
species: 730934

730934
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: ADP_C10H12N5O10P2

755285
type: SpeciesReference
stoichiometry: 3.0
species: 749213

755225
type: SpeciesReference
stoichiometry: 1.0
species: 732453

732453
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: ATP_C10H12N5O13P3

755261
type: SpeciesReference
stoichiometry: 2.0
species: 731767

731767
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: AMP_C10H12N5O7P

755273
type: SpeciesReference
stoichiometry: 3.0
species: 741271

752764
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Trehalose_C12H22O11

747770
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Superoxide anion_O2

035371
type: Reaction
reversible: false
is: http://identifiers.org/ec-code/3.6.1.7
notes: R_ACYP subsystem: Glycolysis/Gluconeogenesis R_ACYP equation: [c] : 13dpg + h2o --> 3pg + h + pi
product: 799991
is: ENSCAFG00000017020.2
is: ENSCAFG00000023070.1
product: 800003
fast: false
is: ENSCAFG00000002938.2
reactant: 799967
name: acylphosphatase
product: 799979
reactant: 799955

799991
type: SpeciesReference
stoichiometry: 1.0
species: 727771

727771
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Phospho-D-glycerate_C3H4O7P

800003
type: SpeciesReference
stoichiometry: 1.0
species: 741259

799967
type: SpeciesReference
stoichiometry: 1.0
species: 741151

799979
type: SpeciesReference
stoichiometry: 1.0
species: 749200

799955
type: SpeciesReference
stoichiometry: 1.0
species: 726500

743685
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 12_C135H218N9O106S3X

730597
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: sialyl (1,3) sialyl (2,6) galactosylgloboside (homo sapiens)_C72H121N4O43FULLRCO

754159
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _7-alpha,27-Dihydroxycholesterol_C27H46O3

733443
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137

741247
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Hydroxy-L-kynurenine_C10H12N2O4

752890
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: testosterone glucuronide_C25H36O8

752398
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Thiamin_C12H17N4OS

040236
type: Reaction
reversible: true
is: ENSCAFG00000005751.2
fast: false
product: 845184
product: 845172
is: ENSCAFG00000004623.2
is: ENSCAFG00000014228.2
notes: R_HCO3_CLt subsystem: Transport, Extracellular R_HCO3_CLt equation: cl[c] + hco3[e] <==> cl[e] + hco3[c]
reactant: 845148
is: ENSCAFG00000015723.2
name: bicarbonate transport (Cl-/HCO3- exchange)
reactant: 845160

845184
type: SpeciesReference
stoichiometry: 1.0
species: 733750

845172
type: SpeciesReference
stoichiometry: 1.0
species: 741416

845148
type: SpeciesReference
stoichiometry: 1.0
species: 733738

845160
type: SpeciesReference
stoichiometry: 1.0
species: 741428

730765
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: O-Acetylcarnitine_C9H17NO4

033547
type: Reaction
notes: R_PETHCT subsystem: Glycerophospholipid Metabolism R_PETHCT equation: [c] : ctp + ethamp + h --> cdpea + ppi R_EPCTX subsystem: Glycerophospholipid Metabolism R_EPCTX equation: [c] : 2ameph + ctp + h --> cmp2amep + ppi
product: 782138
is: http://identifiers.org/ec-code/2.7.7.14
fast: false
product: 782126
reactant: 782090
reactant: 782078
reactant: 782102
reactant: 782114
product: 782150
reversible: false
is: ENSCAFG00000005882.2

782138
type: SpeciesReference
stoichiometry: 1.0
species: 733847

733847
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053

782126
type: SpeciesReference
stoichiometry: 1.0
species: 733262

782090
type: SpeciesReference
stoichiometry: 1.0
species: 737919

782078
type: SpeciesReference
stoichiometry: 1.0
species: 726790

726790
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (2-Aminoethyl)phosphonate_C2H7NO3P

782102
type: SpeciesReference
stoichiometry: 2.0
species: 741259

782114
type: SpeciesReference
stoichiometry: 2.0
species: 735155

735155
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: CTP_C9H12N3O14P3

782150
type: SpeciesReference
stoichiometry: 2.0
species: 749466

731996
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Apocarboxylase (Lys residue)_C6H13N2OX

032114
type: Reaction
product: 769734
notes: R_S6T3g subsystem: Keratan sulfate biosynthesis R_S6T3g equation: [g] : ksii_core2_pre10 + paps --> h + ksii_core2 + pap R_S6T24g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T24g equation: [g] : cs_e_pre4 + paps --> cs_e_pre5b + h + pap R_S6T20g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T20g equation: [g] : cs_c_pre3 + paps --> cspg_c + h + pap R_S6T19g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T19g equation: [g] : cs_pre + (2) paps --> cs_c,d,e_pre1 + (2) h + (2) pap R_S6T18g subsystem: Keratan sulfate biosynthesis R_S6T18g equation: [g] : ksii_core4_pre10 + paps --> h + ksii_core4 + pap R_S6T15g subsystem: Keratan sulfate biosynthesis R_S6T15g equation: [g] : ksi_pre36 + paps --> h + ksi + pap R_S6T21g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T21g equation: [g] : cs_d_pre4 + paps --> cs_d_pre5 + h + pap
product: 769758
reactant: 769686
product: 769770
product: 769806
reactant: 769710
product: 769794
reactant: 769698
product: 769830
is: http://identifiers.org/ec-code/2.8.2.17
product: 769746
reversible: false
is: ENSCAFG00000014410.2
reactant: 769722
reactant: 769674
fast: false
reactant: 769638
reactant: 769662
product: 769782
product: 769818
reactant: 769650

769734
type: SpeciesReference
stoichiometry: 1.0
species: 743636

743636
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I_C247H393N17O213S12X

769758
type: SpeciesReference
stoichiometry: 1.0
species: 735119

769686
type: SpeciesReference
stoichiometry: 1.0
species: 735059

769770
type: SpeciesReference
stoichiometry: 8.0
species: 741283

769806
type: SpeciesReference
stoichiometry: 1.0
species: 744205

744205
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II (core 2-linked)_C81H129N6O67S3X

769710
type: SpeciesReference
stoichiometry: 1.0
species: 744000

744000
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 36_C247H394N17O210S11X

769794
type: SpeciesReference
stoichiometry: 8.0
species: 748663

769698
type: SpeciesReference
stoichiometry: 1.0
species: 735023

769830
type: SpeciesReference
stoichiometry: 1.0
species: 735047

769746
type: SpeciesReference
stoichiometry: 1.0
species: 734658

769722
type: SpeciesReference
stoichiometry: 1.0
species: 744229

744229
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 10_C81H130N6O64S2X

769674
type: SpeciesReference
stoichiometry: 8.0
species: 748687

769638
type: SpeciesReference
stoichiometry: 1.0
species: 744423

744423
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 10_C89H143N7O69S2X

769662
type: SpeciesReference
stoichiometry: 1.0
species: 734755

769782
type: SpeciesReference
stoichiometry: 1.0
species: 734890

769818
type: SpeciesReference
stoichiometry: 1.0
species: 744399

744399
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II (core 4-linked)_C89H142N7O72S3X

769650
type: SpeciesReference
stoichiometry: 1.0
species: 734878

726356
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _11-Deoxycortisol_C21H30O4

036833
type: Reaction
product: 812070
is: ENSCAFG00000010063.2
product: 812058
is: http://identifiers.org/ec-code/1.1.1.95
is: ENSCAFG00000023328.1
is: ENSCAFG00000025283.1
notes: R_PGCD subsystem: Glycine, Serine, and Threonine Metabolism R_PGCD equation: [c] : 3pg + nad --> 3php + h + nadh
is: ENSCAFG00000025426.1
is: ENSCAFG00000010843.2
reactant: 812034
product: 812082
fast: false
reactant: 812046
reversible: false
name: phosphoglycerate dehydrogenase

812070
type: SpeciesReference
stoichiometry: 1.0
species: 741259

812058
type: SpeciesReference
stoichiometry: 1.0
species: 727783

727783
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Phosphohydroxypyruvate_C3H2O7P

812034
type: SpeciesReference
stoichiometry: 1.0
species: 746978

812082
type: SpeciesReference
stoichiometry: 1.0
species: 747050

812046
type: SpeciesReference
stoichiometry: 1.0
species: 727771

746219
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Metanephrine_C10H16NO3

739147
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: D-Galactose_C6H12O6

746822
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-(N-acetyl-beta-D-glucosaminyl-1,4)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R_C58H96N5O40X

753676
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: UTP_C9H11N2O15P3

752483
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Threonine_C4H9NO3

734489
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate A (GalNAc4S-GlcA) and B (IdoA2S-GalNAc4S), precursor 2_C37H54NO37S2X

035047
type: Reaction
is: http://identifiers.org/ec-code/2.4.2.1
modifier: 795130
modifier: 795106
modifier: 795118
modifier: 795178
product: 795045
modifier: 795154
reactant: 795021
reversible: false
modifier: 795274
modifier: 795190
modifier: 795166
modifier: 795202
reactant: 795009
notes: R_PUNP5 subsystem: Purine Catabolism R_PUNP5 equation: [c] : ins + pi <==> hxan + r1p R_PUNP3 subsystem: Purine Catabolism R_PUNP3 equation: [c] : gsn + pi <==> gua + r1p R_PUNP4 subsystem: Purine Catabolism R_PUNP4 equation: [c] : dgsn + pi <==> 2dr1p + gua R_PUNP2 subsystem: Purine Catabolism R_PUNP2 equation: [c] : dad-2 + pi <==> 2dr1p + ade R_PUNP1 subsystem: Nucleotides R_PUNP1 equation: [c] : adn + pi <==> ade + r1p R_PUNP7 subsystem: Nucleotides R_PUNP7 equation: [c] : pi + xtsn <==> r1p + xan R_PUNP6 subsystem: Purine Catabolism R_PUNP6 equation: [c] : din + pi <==> 2dr1p + hxan R_DURIPP subsystem: Nucleotides R_DURIPP equation: [c] : duri + pi <==> 2dr1p + ura R_PNP subsystem: NAD Metabolism R_PNP equation: [c] : pi + rnam <==> h + ncam + r1p R_NP1 subsystem: NAD Metabolism R_NP1 equation: [c] : h + nac + r1p --> nicrns + pi
modifier: 795070
is: ENSCAFG00000005419.2
modifier: 795057
product: 795033
modifier: 795226
fast: false
modifier: 795142
modifier: 795214
reactant: 794997
modifier: 795094
modifier: 795262
modifier: 795082
modifier: 795238
modifier: 795250

736511
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Deoxyinosine_C10H12N4O4

726888
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2-Deoxy-D-ribose 1-phosphate_C5H9O7P

730801
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Adenine_C5H5N5

795045
type: SpeciesReference
stoichiometry: 1.0
species: 747367

747367
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Nicotinate D-ribonucleoside_C11H13NO6

795021
type: SpeciesReference
stoichiometry: 1.0
species: 741259

740749
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Guanosine_C10H13N5O5

753870
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Xanthine_C5H4N4O2

750683
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Ribosylnicotinamide_C11H15N2O5

795009
type: SpeciesReference
stoichiometry: 1.0
species: 746966

746966
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Nicotinate_C6H4NO2

741018
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Guanine_C5H5N5O

795033
type: SpeciesReference
stoichiometry: 1.0
species: 749200

742516
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Hypoxanthine_C5H4N4O

794997
type: SpeciesReference
stoichiometry: 1.0
species: 750478

736023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Deoxyguanosine_C10H13N5O4

735336
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Deoxyadenosine_C10H13N5O3

747258
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Nicotinamide_C6H6N2O

753495
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Uracil_C4H4N2O2

031487
type: Reaction
name: beta-galactoside alpha-2,6-sialyltransferase
product: 763864
notes: R_S26Tg subsystem: N-Glycan Biosynthesis R_S26Tg equation: [g] : (2) cmpacna + l2fn2m2masn --> (2) cmp + (2) h + s2l2fn2m2masn
is: http://identifiers.org/ec-code/2.4.99.1
reversible: false
fast: false
product: 763876
reactant: 763852
product: 763888
reactant: 763840
is: ENSCAFG00000013698.2

763864
type: SpeciesReference
stoichiometry: 2.0
species: 741283

763876
type: SpeciesReference
stoichiometry: 2.0
species: 733884

763852
type: SpeciesReference
stoichiometry: 1.0
species: 744546

763888
type: SpeciesReference
stoichiometry: 1.0
species: 750720

750720
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: PA6_C90H145N6O65X

763840
type: SpeciesReference
stoichiometry: 2.0
species: 733933

038634
type: Reaction
is: ENSCAFG00000008859.2
reactant: 830494
reactant: 830470
reversible: false
is: http://identifiers.org/ec-code/1.15.1.1
product: 830544
product: 830519
product: 830531
reactant: 830458
product: 830557
product: 830506
reactant: 830446
notes: R_SPODMn subsystem: ROS Detoxification R_SPODMn equation: [n] : (2) h + (2) o2s --> h2o2 + o2 R_SPODMx subsystem: ROS Detoxification R_SPODMx equation: [x] : (2) h + (2) o2s --> h2o2 + o2 R_SPODM subsystem: ROS Detoxification R_SPODM equation: [c] : (2) h + (2) o2s --> h2o2 + o2
product: 830570
fast: false
reactant: 830434
reactant: 830482

830494
type: SpeciesReference
stoichiometry: 2.0
species: 741259

830470
type: SpeciesReference
stoichiometry: 2.0
species: 747770

830544
type: SpeciesReference
stoichiometry: 1.0
species: 741139

830519
type: SpeciesReference
stoichiometry: 1.0
species: 741127

741127
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Hydrogen peroxide_H2O2

830531
type: SpeciesReference
stoichiometry: 1.0
species: 747734

747734
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: O2_O2

830458
type: SpeciesReference
stoichiometry: 2.0
species: 741320

741320
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: H+_H

830557
type: SpeciesReference
stoichiometry: 1.0
species: 741078

830506
type: SpeciesReference
stoichiometry: 1.0
species: 747758

830446
type: SpeciesReference
stoichiometry: 2.0
species: 747818

747818
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Superoxide anion_O2

830570
type: SpeciesReference
stoichiometry: 1.0
species: 747698

830434
type: SpeciesReference
stoichiometry: 2.0
species: 747806

747806
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Superoxide anion_O2

830482
type: SpeciesReference
stoichiometry: 2.0
species: 741344

738219
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Fe3+_Fe

749454
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Propanoyl-CoA_C24H36N7O17P3S

041106
type: Reaction
reactant: 854520
reactant: 854581
product: 854593
product: 854617
reversible: false
reactant: 854557
reactant: 854544
reactant: 854532
product: 854689
fast: false
product: 854677
product: 854653
reactant: 854508
reactant: 854569
is: ENSCAFG00000003180.2
product: 854629
product: 854605
notes: R_CYSTHRNaEx subsystem: Transport, Extracellular R_CYSTHRNaEx equation: cys-L[e] + na1[e] + thr-L[c] --> cys-L[c] + na1[c] + thr-L[e] R_THRSERNaEx subsystem: Transport, Extracellular R_THRSERNaEx equation: na1[e] + ser-L[c] + thr-L[e] --> na1[c] + ser-L[e] + thr-L[c] R_ALACYSNaEx subsystem: Transport, Extracellular R_ALACYSNaEx equation: ala-L[e] + cys-L[c] + na1[e] --> ala-L[c] + cys-L[e] + na1[c] R_THRALANaEx subsystem: Transport, Extracellular R_THRALANaEx equation: ala-L[c] + na1[e] + thr-L[e] --> ala-L[e] + na1[c] + thr-L[c] R_CYSALANaEx subsystem: Transport, Extracellular R_CYSALANaEx equation: ala-L[c] + cys-L[e] + na1[e] --> ala-L[e] + cys-L[c] + na1[c] R_SERTHRNaEx subsystem: Transport, Extracellular R_SERTHRNaEx equation: na1[e] + ser-L[e] + thr-L[c] --> na1[c] + ser-L[c] + thr-L[e] R_SERCYSNaEx subsystem: Transport, Extracellular R_SERCYSNaEx equation: cys-L[c] + na1[e] + ser-L[e] --> cys-L[e] + na1[c] + ser-L[c] R_ALASERNaEx subsystem: Transport, Extracellular R_ALASERNaEx equation: ala-L[e] + na1[e] + ser-L[c] --> ala-L[c] + na1[c] + ser-L[e] R_SERALANaEx subsystem: Transport, Extracellular R_SERALANaEx equation: ala-L[c] + na1[e] + ser-L[e] --> ala-L[e] + na1[c] + ser-L[c] R_ALATHRNaEx subsystem: Transport, Extracellular R_ALATHRNaEx equation: ala-L[e] + na1[e] + thr-L[c] --> ala-L[c] + na1[c] + thr-L[e] R_THRCYSNaEx subsystem: Transport, Extracellular R_THRCYSNaEx equation: cys-L[c] + na1[e] + thr-L[e] --> cys-L[e] + na1[c] + thr-L[c] R_CYSSERNaEx subsystem: Transport, Extracellular R_CYSSERNaEx equation: cys-L[e] + na1[e] + ser-L[c] --> cys-L[c] + na1[c] + ser-L[e]
product: 854665
product: 854641
reactant: 854484
reactant: 854496

854520
type: SpeciesReference
stoichiometry: 3.0
species: 735228

735228
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Cysteine_C3H7NO2S

854581
type: SpeciesReference
stoichiometry: 3.0
species: 731549

854593
type: SpeciesReference
stoichiometry: 3.0
species: 751082

854617
type: SpeciesReference
stoichiometry: 3.0
species: 731561

854557
type: SpeciesReference
stoichiometry: 3.0
species: 752483

854544
type: SpeciesReference
stoichiometry: 3.0
species: 752496

752496
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Threonine_C4H9NO3

854532
type: SpeciesReference
stoichiometry: 12.0
species: 746930

854689
type: SpeciesReference
stoichiometry: 3.0
species: 751094

854677
type: SpeciesReference
stoichiometry: 3.0
species: 731549

854653
type: SpeciesReference
stoichiometry: 3.0
species: 752496

854508
type: SpeciesReference
stoichiometry: 3.0
species: 731561

854569
type: SpeciesReference
stoichiometry: 3.0
species: 751094

854629
type: SpeciesReference
stoichiometry: 3.0
species: 735228

854605
type: SpeciesReference
stoichiometry: 3.0
species: 735216

854665
type: SpeciesReference
stoichiometry: 3.0
species: 752483

854641
type: SpeciesReference
stoichiometry: 12.0
species: 746918

854484
type: SpeciesReference
stoichiometry: 3.0
species: 735216

854496
type: SpeciesReference
stoichiometry: 3.0
species: 751082

033657
type: Reaction
fast: false
is: ENSCAFG00000016824.1
is: http://identifiers.org/ec-code/1.1.2.3
reversible: false
notes: R_L_DASH_LACDcm subsystem: Pyruvate Metabolism R_L_DASH_LACDcm equation: (2) ficytC[m] + lac-L[c] --> (2) focytC[m] + (2) h[c] + pyr[c]
product: 783135
name: L-Lactate dehydrogenase, cytosolic/mitochondrial
reactant: 783111
product: 783123
product: 783147
reactant: 783099

783135
type: SpeciesReference
stoichiometry: 1.0
species: 750369

783111
type: SpeciesReference
stoichiometry: 1.0
species: 744637

783123
type: SpeciesReference
stoichiometry: 2.0
species: 738292

738292
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Ferrocytochrome C_C42H54FeN8O6S2

783147
type: SpeciesReference
stoichiometry: 2.0
species: 741259

783099
type: SpeciesReference
stoichiometry: 2.0
species: 738243

738243
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Ferricytochrome c_C42H54FeN8O6S2

749996
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Prostaglandin E1_C20H33O5

730100
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Acetaldehyde_C2H4O

735288
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Cytidine_C9H13N3O5

726876
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _2-Decaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone_C58H88O4

039863
type: Reaction
product: 841641
product: 841629
reversible: false
is: http://identifiers.org/ec-code/4.2.1.24
notes: R_PPBNGS subsystem: Heme Biosynthesis R_PPBNGS equation: [c] : (2) 5aop --> h + (2) h2o + ppbng
reactant: 841617
fast: false
is: ENSCAFG00000003246.2
name: porphobilinogen synthase
product: 841653

841641
type: SpeciesReference
stoichiometry: 2.0
species: 741151

841629
type: SpeciesReference
stoichiometry: 1.0
species: 749418

749418
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Porphobilinogen_C10H13N2O4

841617
type: SpeciesReference
stoichiometry: 2.0
species: 728523

728523
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Amino-4-oxopentanoate_C5H9NO3

841653
type: SpeciesReference
stoichiometry: 1.0
species: 741259

736352
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: _7,8-Dihydrofolate_C19H19N7O6

031897
type: Reaction
product: 767690
fast: false
reactant: 767594
reactant: 767606
reversible: true
reactant: 767642
reactant: 767630
is: ENSCAFG00000016277.2
notes: R_HACD1m subsystem: Tryptophan metabolism R_HACD1m equation: [m] : aacoa + h + nadh <==> 3hbcoa + nad R_HACD9m subsystem: Valine, Leucine, and Isoleucine Metabolism R_HACD9m equation: [m] : 3hmbcoa + nad <==> 2maacoa + h + nadh
reactant: 767618
product: 767702
product: 767654
is: http://identifiers.org/ec-code/1.1.1.35
product: 767666
product: 767678

767690
type: SpeciesReference
stoichiometry: 1.0
species: 741308

767594
type: SpeciesReference
stoichiometry: 1.0
species: 729919

729919
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Acetoacetyl-CoA_C25H36N7O18P3S

767606
type: SpeciesReference
stoichiometry: 1.0
species: 747002

767642
type: SpeciesReference
stoichiometry: 1.0
species: 747062

767630
type: SpeciesReference
stoichiometry: 1.0
species: 741308

767618
type: SpeciesReference
stoichiometry: 1.0
species: 727420

727420
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113

767702
type: SpeciesReference
stoichiometry: 1.0
species: 747062

767654
type: SpeciesReference
stoichiometry: 1.0
species: 727384

727384
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113

767666
type: SpeciesReference
stoichiometry: 1.0
species: 726949

726949
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113

767678
type: SpeciesReference
stoichiometry: 1.0
species: 747002

038233
type: Reaction
fast: false
reactant: 827269
product: 827281
is: ENSCAFG00000005589.2
reversible: false
is: http://identifiers.org/ec-code/3.2.1.20
reactant: 827257
reactant: 827245
notes: R_MALTly subsystem: Starch and Sucrose Metabolism R_MALTly equation: [l] : h2o + malt --> (2) glc-D R_MLTG1ly subsystem: Starch and Sucrose Metabolism R_MLTG1ly equation: [l] : h2o + malttr --> glc-D + malt
product: 827293

827269
type: SpeciesReference
stoichiometry: 1.0
species: 745988

745988
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Maltose_C12H22O11

827281
type: SpeciesReference
stoichiometry: 3.0
species: 739852

739852
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: D-Glucose_C6H12O6

827257
type: SpeciesReference
stoichiometry: 2.0
species: 741187

827245
type: SpeciesReference
stoichiometry: 1.0
species: 746025

746025
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Maltotriose_C18H32O16

827293
type: SpeciesReference
stoichiometry: 1.0
species: 745988

035973
type: Reaction
product: 805020
reactant: 804587
reactant: 804743
reactant: 804731
product: 804984
product: 804875
product: 805153
product: 805165
reactant: 804767
product: 804887
reactant: 804623
product: 804911
product: 804839
is: ENSCAFG00000012076.1
product: 804899
reactant: 804539
reversible: false
reactant: 804454
product: 804923
product: 804851
reactant: 804659
reactant: 804647
reactant: 804382
product: 804791
product: 804863
product: 804935
reactant: 804478
reactant: 804707
product: 805032
product: 804947
product: 804959
reactant: 804406
reactant: 804575
reactant: 804695
reactant: 804683
product: 805081
fast: false
product: 805093
reactant: 804599
reactant: 804755
product: 805045
product: 805057
reactant: 804442
product: 805069
reactant: 804611
product: 804971
reactant: 804466
product: 805117
reactant: 804527
reactant: 804430
reactant: 804515
reactant: 804394
product: 805129
reactant: 804635
product: 804803
reactant: 804719
notes: R_RTOTALCRNt subsystem: Carnitine shuttle R_RTOTALCRNt equation: Rtotalcrn[c] --> Rtotalcrn[m] R_LNLNCGCRNt subsystem: Carnitine shuttle R_LNLNCGCRNt equation: lnlncgcrn[c] --> lnlncgcrn[m] R_ACRNtm subsystem: Transport, Mitochondrial R_ACRNtm equation: acrn[c] --> acrn[m] R_LNLNCACRNt subsystem: Carnitine shuttle R_LNLNCACRNt equation: lnlncacrn[c] --> lnlncacrn[m] R_DLNLCGCRNt subsystem: Carnitine shuttle R_DLNLCGCRNt equation: dlnlcgcrn[c] --> dlnlcgcrn[m] R_STRDNCCRNt subsystem: Carnitine shuttle R_STRDNCCRNt equation: strdnccrn[c] --> strdnccrn[m] R_CRNtim subsystem: Transport, Mitochondrial R_CRNtim equation: crn[m] --> crn[c] R_TETTET6CRNt subsystem: Carnitine shuttle R_TETTET6CRNt equation: tettet6crn[c] --> tettet6crn[m] R_RTOTAL2CRNt subsystem: Carnitine shuttle R_RTOTAL2CRNt equation: Rtotal2crn[c] --> Rtotal2crn[m] R_DCSPTN1CRNt subsystem: Carnitine shuttle R_DCSPTN1CRNt equation: dcsptn1crn[c] --> dcsptn1crn[m] R_C161CRN2t subsystem: Carnitine shuttle R_C161CRN2t equation: hdd2crn[c] --> hdd2crn[m] R_C181CRNt subsystem: Carnitine shuttle R_C181CRNt equation: odecrn[c] --> odecrn[m] R_EICOSTETCRNt subsystem: Carnitine shuttle R_EICOSTETCRNt equation: eicostetcrn[c] --> eicostetcrn[m] R_TTDCRNt subsystem: Carnitine shuttle R_TTDCRNt equation: ttdcrn[c] --> ttdcrn[m] R_TMNDNCCRNt subsystem: Carnitine shuttle R_TMNDNCCRNt equation: tmndnccrn[c] --> tmndnccrn[m] R_CLPNDCRNt subsystem: Carnitine shuttle R_CLPNDCRNt equation: clpndcrn[c] --> clpndcrn[m] R_LGNCCRNt subsystem: Carnitine shuttle R_LGNCCRNt equation: lgnccrn[c] --> lgnccrn[m] R_VACCCRNt subsystem: Carnitine shuttle R_VACCCRNt equation: vacccrn[c] --> vacccrn[m] R_ADRNCRNt subsystem: Carnitine shuttle R_ADRNCRNt equation: adrncrn[c] --> adrncrn[m] R_NRVNCCRNt subsystem: Carnitine shuttle R_NRVNCCRNt equation: nrvnccrn[c] --> nrvnccrn[m] R_TETPENT6CRNt subsystem: Carnitine shuttle R_TETPENT6CRNt equation: tetpent6crn[c] --> tetpent6crn[m] R_LNELDCCRNt subsystem: Carnitine shuttle R_LNELDCCRNt equati…
product: 804779
product: 805141
product: 804815
product: 804996
product: 804827
reactant: 804502
product: 805105
reactant: 804563
reactant: 804551
reactant: 804490
product: 805008
reactant: 804671
reactant: 804418

805020
type: SpeciesReference
stoichiometry: 1.0
species: 745001

745001
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: lignoceryl carnitine_C31H61NO4

804587
type: SpeciesReference
stoichiometry: 1.0
species: 751506

751506
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: stearoylcarnitine_C25H49NO4

804743
type: SpeciesReference
stoichiometry: 1.0
species: 745170

745170
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Linoleyl carnitine_C25H45NO4

804731
type: SpeciesReference
stoichiometry: 1.0
species: 741717

741717
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: hexacosanoyl carnitine_C33H65NO4

804984
type: SpeciesReference
stoichiometry: 1.0
species: 730765

804875
type: SpeciesReference
stoichiometry: 1.0
species: 741548

741548
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Hexadecenoyl carnitine_C23H43NO4

805153
type: SpeciesReference
stoichiometry: 1.0
species: 753738

753738
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Vaccenyl carnitine_C25H47NO4

805165
type: SpeciesReference
stoichiometry: 1.0
species: 741633

741633
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: trans-Hexadec-2-enoyl carnitine_C23H43NO4

804767
type: SpeciesReference
stoichiometry: 1.0
species: 741947

804887
type: SpeciesReference
stoichiometry: 1.0
species: 741959

741959
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: heptadecanoyl carnitine_C24H47NO4

804623
type: SpeciesReference
stoichiometry: 1.0
species: 732128

732128
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: arachidyl carnitine_C27H53NO4

804911
type: SpeciesReference
stoichiometry: 1.0
species: 733835

733835
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: clupanodonyl carnitine_C29H47NO4

804839
type: SpeciesReference
stoichiometry: 1.0
species: 729573

729573
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: R total 2 carnitine_CO2FULLR2C7H14NO2

804899
type: SpeciesReference
stoichiometry: 1.0
species: 741729

741729
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: hexacosanoyl carnitine_C33H65NO4

804539
type: SpeciesReference
stoichiometry: 1.0
species: 750225

750225
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: pendtadenoyl carnitine_C22H43NO4

804454
type: SpeciesReference
stoichiometry: 1.0
species: 741621

741621
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: trans-Hexadec-2-enoyl carnitine_C23H43NO4

804923
type: SpeciesReference
stoichiometry: 1.0
species: 747662

747662
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Nervonyl carnitine_C31H59NO4

804851
type: SpeciesReference
stoichiometry: 1.0
species: 737606

804659
type: SpeciesReference
stoichiometry: 1.0
species: 735685

804647
type: SpeciesReference
stoichiometry: 1.0
species: 752049

752049
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosapentaenoyl carnitine_C31H51NO4

804382
type: SpeciesReference
stoichiometry: 1.0
species: 745302

745302
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: gamma-linolenyl carnitine_C25H43NO4

804791
type: SpeciesReference
stoichiometry: 1.0
species: 732140

732140
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: arachidyl carnitine_C27H53NO4

804863
type: SpeciesReference
stoichiometry: 1.0
species: 751518

804935
type: SpeciesReference
stoichiometry: 1.0
species: 731152

731152
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Adrenyl carnitine_C29H49NO4

804478
type: SpeciesReference
stoichiometry: 1.0
species: 749334

749334
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Palmitoylcarnitine_C23H45NO4

804707
type: SpeciesReference
stoichiometry: 1.0
species: 745109

745109
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Linoelaidyl carnitine_C25H45NO4

805032
type: SpeciesReference
stoichiometry: 1.0
species: 750237

750237
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: pendtadenoyl carnitine_C22H43NO4

804947
type: SpeciesReference
stoichiometry: 1.0
species: 737569

737569
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Eicosatetranoyl carnitine_C27H45NO4

804959
type: SpeciesReference
stoichiometry: 1.0
species: 734345

734345
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Carnitine_C7H15NO3

804406
type: SpeciesReference
stoichiometry: 1.0
species: 752121

752121
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosapentaenoyl carnitine_C31H51NO4

804575
type: SpeciesReference
stoichiometry: 1.0
species: 737557

737557
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Eicosatetranoyl carnitine_C27H45NO4

804695
type: SpeciesReference
stoichiometry: 1.0
species: 753725

753725
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Vaccenyl carnitine_C25H47NO4

804683
type: SpeciesReference
stoichiometry: 1.0
species: 747650

747650
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Nervonyl carnitine_C31H59NO4

805081
type: SpeciesReference
stoichiometry: 1.0
species: 745242

745242
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: alpha-linolenyl carnitine_C25H43NO4

805093
type: SpeciesReference
stoichiometry: 1.0
species: 752133

752133
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: tetracosapentaenoyl carnitine_C31H51NO4

804599
type: SpeciesReference
stoichiometry: 1.0
species: 729561

729561
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: R total 2 carnitine_CO2FULLR2C7H14NO2

804755
type: SpeciesReference
stoichiometry: 1.0
species: 752193

805045
type: SpeciesReference
stoichiometry: 1.0
species: 753022

753022
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: tetradecanoyl carnitine_C21H41NO4

805057
type: SpeciesReference
stoichiometry: 1.0
species: 729648

729648
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: R total 3 carnitine_CO2FULLR3C7H14NO2

804442
type: SpeciesReference
stoichiometry: 1.0
species: 748121

748121
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: octadecenoyl carnitine_C25H47NO4

805069
type: SpeciesReference
stoichiometry: 1.0
species: 735697

735697
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: docosa-4,7,10,13,16-pentaenoyl carnitine_C29H47NO4

804611
type: SpeciesReference
stoichiometry: 1.0
species: 733822

733822
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: clupanodonyl carnitine_C29H47NO4

804971
type: SpeciesReference
stoichiometry: 1.0
species: 749346

749346
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Palmitoylcarnitine_C23H45NO4

804466
type: SpeciesReference
stoichiometry: 1.0
species: 731139

731139
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Adrenyl carnitine_C29H49NO4

805117
type: SpeciesReference
stoichiometry: 1.0
species: 752205

752205
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Tetracosatetraenoyl carnitine_C31H53NO4

804527
type: SpeciesReference
stoichiometry: 1.0
species: 752679

752679
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Timnodonyl carnitine_C27H43NO4

804430
type: SpeciesReference
stoichiometry: 1.0
species: 741536

741536
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Hexadecenoyl carnitine_C23H43NO4

804515
type: SpeciesReference
stoichiometry: 1.0
species: 753010

753010
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetradecanoyl carnitine_C21H41NO4

804394
type: SpeciesReference
stoichiometry: 1.0
species: 744989

744989
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: lignoceryl carnitine_C31H61NO4

805129
type: SpeciesReference
stoichiometry: 1.0
species: 736620

736620
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: dihomo-gamma-linolenyl carnitine_C27H47NO4

804635
type: SpeciesReference
stoichiometry: 1.0
species: 734369

734369
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Carnitine_C7H15NO3

804803
type: SpeciesReference
stoichiometry: 1.0
species: 745122

745122
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Linoelaidyl carnitine_C25H45NO4

804719
type: SpeciesReference
stoichiometry: 1.0
species: 751603

751603
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: stearidonyl carnitine_C25H41NO4

804779
type: SpeciesReference
stoichiometry: 1.0
species: 729762

729762
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: R total carnitine_CO2FULLRC7H14NO2

805141
type: SpeciesReference
stoichiometry: 1.0
species: 745182

804815
type: SpeciesReference
stoichiometry: 1.0
species: 752691

752691
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Timnodonyl carnitine_C27H43NO4

804996
type: SpeciesReference
stoichiometry: 1.0
species: 752061

752061
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: tetracosapentaenoyl carnitine_C31H51NO4

804827
type: SpeciesReference
stoichiometry: 1.0
species: 745315

745315
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: gamma-linolenyl carnitine_C25H43NO4

804502
type: SpeciesReference
stoichiometry: 1.0
species: 745230

745230
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: alpha-linolenyl carnitine_C25H43NO4

805105
type: SpeciesReference
stoichiometry: 1.0
species: 748133

748133
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: octadecenoyl carnitine_C25H47NO4

804563
type: SpeciesReference
stoichiometry: 1.0
species: 730753

730753
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: O-Acetylcarnitine_C9H17NO4

804551
type: SpeciesReference
stoichiometry: 1.0
species: 737594

804490
type: SpeciesReference
stoichiometry: 1.0
species: 729750

729750
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: R total carnitine_CO2FULLRC7H14NO2

805008
type: SpeciesReference
stoichiometry: 1.0
species: 751615

804671
type: SpeciesReference
stoichiometry: 1.0
species: 729635

729635
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: R total 3 carnitine_CO2FULLR3C7H14NO2

804418
type: SpeciesReference
stoichiometry: 1.0
species: 736608

736608
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dihomo-gamma-linolenyl carnitine_C27H47NO4

738438
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Farnesyl diphosphate_C15H25O7P2

728994
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _6-Phospho-D-gluconate_C6H10O10P

039563
type: Reaction
product: 839017
reactant: 839005
reactant: 838993
fast: false
reversible: false
is: ENSCAFG00000017836.1
name: glucosaminylphosphatidyl inositol acetyltransferase
notes: R_GPIAT subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIAT equation: [c] : gpail_hs + pmtcoa --> coa + gacpail_hs
product: 839029

839017
type: SpeciesReference
stoichiometry: 1.0
species: 734054

839005
type: SpeciesReference
stoichiometry: 1.0
species: 740639

740639
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053

838993
type: SpeciesReference
stoichiometry: 1.0
species: 749297

839029
type: SpeciesReference
stoichiometry: 1.0
species: 739075

739075
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053

736486
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Digalactosylceramide_C30H56NO12FULLRCO

726961
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113

751759
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: triacylglycerol (homo sapiens)_C3H5FULLRCO2FULLR2CO2FULLR3CO2

037303
type: Reaction
reversible: true
fast: false
product: 816801
product: 816837
reactant: 816789
reactant: 816765
reactant: 816777
notes: R_DCK1n subsystem: Nucleotides R_DCK1n equation: [n] : atp + dcyt <==> adp + dcmp + h R_DCK2n subsystem: Nucleotides R_DCK2n equation: [n] : dcyt + utp <==> dcmp + h + udp
product: 816813
is: http://identifiers.org/ec-code/2.7.1.74
product: 816825
is: ENSCAFG00000002931.2

816801
type: SpeciesReference
stoichiometry: 2.0
species: 741320

816837
type: SpeciesReference
stoichiometry: 2.0
species: 735625

735625
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: dCMP_C9H12N3O7P

816789
type: SpeciesReference
stoichiometry: 1.0
species: 732477

732477
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: ATP_C10H12N5O13P3

816765
type: SpeciesReference
stoichiometry: 2.0
species: 735769

735769
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Deoxycytidine_C9H13N3O4

816777
type: SpeciesReference
stoichiometry: 1.0
species: 753676

816813
type: SpeciesReference
stoichiometry: 1.0
species: 753194

753194
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: UDP_C9H11N2O12P2

816825
type: SpeciesReference
stoichiometry: 1.0
species: 730958

730958
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: ADP_C10H12N5O10P2

744892
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Leukotriene C4_C30H45N3O9S

031005
type: Reaction
reversible: false
reactant: 759690
reactant: 759702
fast: false
product: 759787
reactant: 759714
is: ENSCAFG00000024513.1
is: http://identifiers.org/ec-code/2.7.1.137
is: ENSCAFG00000009661.2
product: 759799
reactant: 759630
product: 759824
product: 759836
product: 759811
reactant: 759642
notes: R_PI4P3K subsystem: Inositol Phosphate Metabolism R_PI4P3K equation: [c] : atp + pail4p_hs --> adp + h + pail34p_hs R_PIK3er subsystem: Inositol Phosphate Metabolism R_PIK3er equation: [r] : atp + pail_hs --> adp + h + pail3p_hs R_PIK3 subsystem: Inositol Phosphate Metabolism R_PIK3 equation: [c] : atp + pail_hs --> adp + h + pail3p_hs R_PI5P3Ker subsystem: Inositol Phosphate Metabolism R_PI5P3Ker equation: [r] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI5P3K subsystem: Inositol Phosphate Metabolism R_PI5P3K equation: [c] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI4P3Ker subsystem: Inositol Phosphate Metabolism R_PI4P3Ker equation: [r] : atp + pail4p_hs --> adp + h + pail34p_hs
product: 759763
reactant: 759654
product: 759726
product: 759751
product: 759739
reactant: 759678
reactant: 759666
product: 759775

759690
type: SpeciesReference
stoichiometry: 3.0
species: 732441

759702
type: SpeciesReference
stoichiometry: 1.0
species: 748555

748555
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

759787
type: SpeciesReference
stoichiometry: 1.0
species: 748459

748459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphatidylinositol-3,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

759714
type: SpeciesReference
stoichiometry: 3.0
species: 732489

732489
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: ATP_C10H12N5O13P3

759799
type: SpeciesReference
stoichiometry: 1.0
species: 748447

748447
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: phosphatidylinositol-3,4-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

759630
type: SpeciesReference
stoichiometry: 1.0
species: 748591

759824
type: SpeciesReference
stoichiometry: 3.0
species: 741332

759836
type: SpeciesReference
stoichiometry: 3.0
species: 741259

759811
type: SpeciesReference
stoichiometry: 1.0
species: 748495

748495
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _1-Phosphatidyl-1D-myo-inositol 3-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

759642
type: SpeciesReference
stoichiometry: 1.0
species: 748531

759763
type: SpeciesReference
stoichiometry: 3.0
species: 730970

730970
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: ADP_C10H12N5O10P2

759654
type: SpeciesReference
stoichiometry: 1.0
species: 748567

748567
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1-Phosphatidyl-1D-myo-inositol 5-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

759726
type: SpeciesReference
stoichiometry: 1.0
species: 748435

748435
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphatidylinositol-3,4-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

759751
type: SpeciesReference
stoichiometry: 1.0
species: 748471

748471
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: phosphatidylinositol-3,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

759739
type: SpeciesReference
stoichiometry: 3.0
species: 730922

759678
type: SpeciesReference
stoichiometry: 1.0
species: 748579

748579
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _1-Phosphatidyl-1D-myo-inositol 5-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

759666
type: SpeciesReference
stoichiometry: 1.0
species: 748615

748615
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: phosphatidylinositol (homo sapiens)_C9H16O9PFULLRCO2FULLR2CO2

759775
type: SpeciesReference
stoichiometry: 1.0
species: 748483

735553
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dCDP_C9H12N3O10P2

737870
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Estrone 3-sulfate_C18H21O5S

732901
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Benzoate_C7H5O2

741380
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: hyaluronan_C28H40N2O22

036809
type: Reaction
reactant: 811866
notes: R_AMETt2m subsystem: Transport, Mitochondrial R_AMETt2m equation: ahcys[m] + amet[c] <==> ahcys[c] + amet[m]
product: 811890
product: 811902
reactant: 811878
name: S-Adenosyl-L-methionine reversible transport, mitochondrial
is: ENSCAFG00000006689.2
reversible: true
fast: false

811866
type: SpeciesReference
stoichiometry: 1.0
species: 731285

731285
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

811890
type: SpeciesReference
stoichiometry: 1.0
species: 731273

811902
type: SpeciesReference
stoichiometry: 1.0
species: 731706

811878
type: SpeciesReference
stoichiometry: 1.0
species: 731694

745699
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Mannosyl)6-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1605H2640N20O520P20

726162
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19

737423
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-erythro-4-Hydroxyglutamate_C5H8NO5

032823
type: Reaction
notes: R_PROAKGOX1r subsystem: Arginine and Proline Metabolism R_PROAKGOX1r equation: [r] : akg + o2 + pro-L --> 4hpro-LT + co2 + succ
is: ENSCAFG00000000824.2
product: 776588
fast: false
reactant: 776551
is: ENSCAFG00000005859.2
is: ENSCAFG00000014573.2
reactant: 776575
is: http://identifiers.org/ec-code/1.14.11.2
name: L-Proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) (ER)
reversible: false
product: 776612
reactant: 776563
product: 776600

776588
type: SpeciesReference
stoichiometry: 1.0
species: 728161

728161
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: trans-4-Hydroxy-L-proline_C5H9NO3

776551
type: SpeciesReference
stoichiometry: 1.0
species: 747746

776575
type: SpeciesReference
stoichiometry: 1.0
species: 749923

749923
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: L-Proline_C5H9NO2

776612
type: SpeciesReference
stoichiometry: 1.0
species: 751663

751663
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Succinate_C4H4O4

776563
type: SpeciesReference
stoichiometry: 1.0
species: 731441

731441
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _2-Oxoglutarate_C5H4O5

776600
type: SpeciesReference
stoichiometry: 1.0
species: 734018

743084
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: potassium_K

738618
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089

726814
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2-Carboxy-2,3-dihydro-5,6-dihydroxyindole_C9H8NO4

737678
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Estradiol_C18H24O2

038343
type: Reaction
is: ENSCAFG00000018766.2
reversible: false
notes: R_Htm subsystem: Transport, Mitochondrial R_Htm equation: h[c] --> h[m]
is: ENSCAFG00000005559.2
product: 828278
reactant: 828266
name: Uncoupling protein
is: ENSCAFG00000005564.2
fast: false
is: ENSCAFG00000002029.2
is: ENSCAFG00000003684.2

828278
type: SpeciesReference
stoichiometry: 1.0
species: 741308

828266
type: SpeciesReference
stoichiometry: 1.0
species: 741259

728088
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _4-Hydroxybenzoate_C7H5O3

035792
type: Reaction
reactant: 802929
product: 803049
is: ENSCAFG00000023593.1
reactant: 802953
product: 803025
reactant: 802965
product: 802989
fast: false
product: 803037
reversible: false
reactant: 802977
product: 803001
is: ENSCAFG00000023467.1
is: ENSCAFG00000002590.2
notes: R_PTE2x subsystem: Fatty Acid Metabolism R_PTE2x equation: [x] : h2o + pmtcoa --> coa + h + hdca R_PTE5x subsystem: Fatty Acid Metabolism R_PTE5x equation: [x] : adrncoa + h2o --> adrn + coa + h R_PTE3x subsystem: Fatty Acid Metabolism R_PTE3x equation: [x] : h2o + pristcoa --> coa + h + prist R_PTE4x subsystem: Fatty Acid Metabolism R_PTE4x equation: [x] : h2o + phytcoa --> coa + h + phyt
is: ENSCAFG00000016848.2
product: 803013
reactant: 802941

802929
type: SpeciesReference
stoichiometry: 1.0
species: 749322

749322
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S

803049
type: SpeciesReference
stoichiometry: 1.0
species: 741512

802953
type: SpeciesReference
stoichiometry: 4.0
species: 741235

803025
type: SpeciesReference
stoichiometry: 4.0
species: 741344

802965
type: SpeciesReference
stoichiometry: 1.0
species: 731127

731127
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: adrenyl coenzyme A_C43H66N7O17P3S

802989
type: SpeciesReference
stoichiometry: 1.0
species: 731090

731090
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: adrenic acid_C22H35O2

803037
type: SpeciesReference
stoichiometry: 1.0
species: 749767

749767
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: pristanic acid_C19H37O2

802977
type: SpeciesReference
stoichiometry: 1.0
species: 749188

749188
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: phytanyl coa_C41H70N7O17P3S

803001
type: SpeciesReference
stoichiometry: 1.0
species: 749164

749164
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: phytanic acid_C20H39O2

803013
type: SpeciesReference
stoichiometry: 4.0
species: 734127

802941
type: SpeciesReference
stoichiometry: 1.0
species: 749815

749815
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: pristanoyl coa_C40H68N7O17P3S

ORG:
  orgname: University of Missouri
n:
  given: Michaël
  family: Bekaert

741584
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053

036253
type: Reaction
reversible: false
notes: R_NNMT subsystem: NAD Metabolism R_NNMT equation: [c] : amet + ncam --> 1mncam + ahcys
product: 807857
is: ENSCAFG00000011591.2
product: 807845
is: http://identifiers.org/ec-code/2.1.1.1
reactant: 807833
fast: false
reactant: 807821
name: Nicotinamide N-methyltransferase

807857
type: SpeciesReference
stoichiometry: 1.0
species: 726620

726620
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1-Methylnicotinamide_C7H9N2O

807845
type: SpeciesReference
stoichiometry: 1.0
species: 731273

807833
type: SpeciesReference
stoichiometry: 1.0
species: 747258

807821
type: SpeciesReference
stoichiometry: 1.0
species: 731694

726572
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _18 hydroxy arachidonic acid_C20H31O3

031583
type: Reaction
reactant: 764528
is: ENSCAFG00000010793.2
product: 764564
reactant: 764516
product: 764552
notes: R_KCC2t subsystem: Transport, Extracellular R_KCC2t equation: cl[e] + nh4[e] <==> cl[c] + nh4[c] R_KCCt subsystem: Transport, Extracellular R_KCCt equation: cl[e] + k[e] <==> cl[c] + k[c]
is: ENSCAFG00000020329.2
reversible: true
is: ENSCAFG00000007885.2
fast: false
reactant: 764540
product: 764576

764528
type: SpeciesReference
stoichiometry: 1.0
species: 747307

747307
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Ammonium_H4N

764564
type: SpeciesReference
stoichiometry: 2.0
species: 733738

764516
type: SpeciesReference
stoichiometry: 1.0
species: 743084

764552
type: SpeciesReference
stoichiometry: 1.0
species: 743072

764540
type: SpeciesReference
stoichiometry: 2.0
species: 733750

764576
type: SpeciesReference
stoichiometry: 1.0
species: 747294

742782
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Isoleucine_C6H13NO2

748182
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: naphthalene epoxide_C10H8O

038076
type: Reaction
reactant: 826210
product: 826299
is: http://identifiers.org/ec-code/2.7.1.137
is: http://identifiers.org/ec-code/2.7.1.153
product: 826262
is: ENSCAFG00000014978.2
is: ENSCAFG00000004331.2
is: ENSCAFG00000007579.2
reactant: 826236
is: ENSCAFG00000017387.2
reversible: false
product: 826287
notes: R_PI45P3K subsystem: Inositol Phosphate Metabolism R_PI45P3K equation: [c] : atp + pail45p_hs --> adp + h + pail345p_hs R_PIK3 subsystem: Inositol Phosphate Metabolism R_PIK3 equation: [c] : atp + pail_hs --> adp + h + pail3p_hs R_PI5P3K subsystem: Inositol Phosphate Metabolism R_PI5P3K equation: [c] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI4P3K subsystem: Inositol Phosphate Metabolism R_PI4P3K equation: [c] : atp + pail4p_hs --> adp + h + pail34p_hs
is: ENSCAFG00000003977.2
reactant: 826223
reactant: 826197
product: 826275
is: ENSCAFG00000007626.2
product: 826323
product: 826311
fast: false
is: ENSCAFG00000004468.2
is: ENSCAFG00000011212.2
reactant: 826249

826210
type: SpeciesReference
stoichiometry: 4.0
species: 732441

826299
type: SpeciesReference
stoichiometry: 4.0
species: 730922

826262
type: SpeciesReference
stoichiometry: 1.0
species: 748411

826236
type: SpeciesReference
stoichiometry: 1.0
species: 748591

826287
type: SpeciesReference
stoichiometry: 1.0
species: 748435

826223
type: SpeciesReference
stoichiometry: 1.0
species: 748507

748507
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphatidylinositol 4,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

826197
type: SpeciesReference
stoichiometry: 1.0
species: 748567

826275
type: SpeciesReference
stoichiometry: 1.0
species: 748459

826323
type: SpeciesReference
stoichiometry: 4.0
species: 741259

826311
type: SpeciesReference
stoichiometry: 1.0
species: 748483

826249
type: SpeciesReference
stoichiometry: 1.0
species: 748531

039647
type: Reaction
product: 839534
reactant: 839522
notes: R_RAI3 subsystem: Vitamin A Metabolism R_RAI3 equation: [c] : retn <==> 13-cis-retn
is: ENSCAFG00000019812.2
fast: false
reversible: true
name: _13-cis-retinoic acid isomerase

839534
type: SpeciesReference
stoichiometry: 1.0
species: 726452

726452
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _13-cis-retinoate_C20H27O2

839522
type: SpeciesReference
stoichiometry: 1.0
species: 750622

750622
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Retinoate_C20H27O2

035900
type: Reaction
is: ENSCAFG00000023379.1
name: sodium proton antiporter (H:NA is 1:1)
notes: R_NAt3_1 subsystem: Transport, Extracellular R_NAt3_1 equation: h[e] + na1[c] <==> h[c] + na1[e]
product: 803821
reversible: true
reactant: 803784
is: ENSCAFG00000001672.2
product: 803809
fast: false
reactant: 803796

803821
type: SpeciesReference
stoichiometry: 1.0
species: 741259

803784
type: SpeciesReference
stoichiometry: 1.0
species: 741271

803809
type: SpeciesReference
stoichiometry: 1.0
species: 746930

803796
type: SpeciesReference
stoichiometry: 1.0
species: 746918

745615
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Mannosyl)5-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1600H2628N20O470P20

739729
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: GDP-L-fucose_C16H23N5O15P2

032511
type: Reaction
product: 773957
reactant: 773908
product: 773944
reversible: false
product: 773981
is: ENSCAFG00000001649.1
product: 773969
reactant: 773932
is: http://identifiers.org/ec-code/2.4.1.102
notes: R_CORE2GTg subsystem: O-Glycan Biosynthesis R_CORE2GTg equation: [g] : T_antigen + uacgam --> core2 + h + udp R_CORE6GTg subsystem: O-Glycan Biosynthesis R_CORE6GTg equation: [g] : Tn_antigen + uacgam --> core6 + h + udp
fast: false
reactant: 773920

773957
type: SpeciesReference
stoichiometry: 2.0
species: 741283

773908
type: SpeciesReference
stoichiometry: 2.0
species: 753121

773944
type: SpeciesReference
stoichiometry: 2.0
species: 753157

773981
type: SpeciesReference
stoichiometry: 1.0
species: 734151

734151
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Core 2_C22H37N2O15X

773969
type: SpeciesReference
stoichiometry: 1.0
species: 734187

734187
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Core 6_C16H27N2O10X

773932
type: SpeciesReference
stoichiometry: 1.0
species: 729858

729858
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Tn antigen_C8H14NO5X

773920
type: SpeciesReference
stoichiometry: 1.0
species: 729846

729846
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: T antigen (core 1)_C14H24NO10X

738762
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)1 (Cer)1_C78H135N4O46FULLRCO

748934
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Peptidyl-L-lysine_XH

030741
type: Reaction
reactant: 757467
reactant: 757455
product: 757516
is: ENSCAFG00000019517.2
fast: false
reactant: 757443
reversible: false
product: 757480
reactant: 757432
is: http://identifiers.org/ec-code/3.2.1.113
product: 757504
notes: R_MAN1_7Ber subsystem: N-Glycan Biosynthesis R_MAN1_7Ber equation: [r] : g1m8masn + h2o --> g1m7masnB + man R_MAN1_6B1er subsystem: N-Glycan Biosynthesis R_MAN1_6B1er equation: [r] : g1m7masnC + h2o --> g1m6masnB1 + man R_MM8Ber subsystem: N-Glycan Biosynthesis R_MM8Ber equation: [r] : h2o + m8masn --> m7masnB + man
product: 757492

757467
type: SpeciesReference
stoichiometry: 1.0
species: 738882

738882
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Glucosyl)-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C76H127N2O60X

757455
type: SpeciesReference
stoichiometry: 3.0
species: 741223

757516
type: SpeciesReference
stoichiometry: 1.0
species: 745735

745735
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein)_C64H107N2O50X

757443
type: SpeciesReference
stoichiometry: 1.0
species: 738870

738870
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: glucosyl-(alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform C (protein)_C70H117N2O55X

757480
type: SpeciesReference
stoichiometry: 3.0
species: 746110

746110
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: D-Mannose_C6H12O6

757432
type: SpeciesReference
stoichiometry: 1.0
species: 745796

745796
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C70H117N2O55X

757504
type: SpeciesReference
stoichiometry: 1.0
species: 738846

757492
type: SpeciesReference
stoichiometry: 1.0
species: 738858

738858
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: glucosyl-(alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein)_C70H117N2O55X

741102
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Hydrogen peroxide_H2O2

033644
type: Reaction
product: 783075
product: 783039
reactant: 782931
reactant: 782847
product: 783003
is: ENSCAFG00000008339.2
reactant: 782859
is: http://identifiers.org/ec-code/1.2.1.38
is: http://identifiers.org/ec-code/2.7.2.11
product: 782979
fast: false
reactant: 782955
reactant: 782943
reactant: 782883
product: 782967
is: http://identifiers.org/ec-code/1.2.1.41
is: http://identifiers.org/ec-code/1.2.1.21
product: 783063
reactant: 782895
product: 783027
reactant: 782919
reactant: 782871
reactant: 782907
reversible: false
product: 782991
product: 783087
product: 783015
reactant: 782835
notes: R_LCADim subsystem: Pyruvate Metabolism R_LCADim equation: [m] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDDm subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDDm equation: [m] : gcald + h2o + nad --> glyclt + (2) h + nadh R_G5SDym subsystem: Urea cycle/amino group metabolism R_G5SDym equation: [m] : glu5p + h + nadph --> glu5sa + nadp + pi R_GLU5Km subsystem: Urea cycle/amino group metabolism R_GLU5Km equation: [m] : atp + glu-L --> adp + glu5p R_AGPRim subsystem: Urea cycle/amino group metabolism R_AGPRim equation: [m] : acg5p + h + nadph --> acg5sa + nadp + pi R_LCADi_Dm subsystem: Pyruvate Metabolism R_LCADi_Dm equation: [m] : h2o + lald-D + nad --> (2) h + lac-D + nadh
product: 783051

783075
type: SpeciesReference
stoichiometry: 6.0
species: 741308

783039
type: SpeciesReference
stoichiometry: 1.0
species: 739975

782931
type: SpeciesReference
stoichiometry: 2.0
species: 747185

782847
type: SpeciesReference
stoichiometry: 3.0
species: 741199

783003
type: SpeciesReference
stoichiometry: 2.0
species: 749249

782859
type: SpeciesReference
stoichiometry: 1.0
species: 744688

782979
type: SpeciesReference
stoichiometry: 1.0
species: 730259

730259
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: N-Acetyl-L-glutamate 5-semialdehyde_C7H10NO4

782955
type: SpeciesReference
stoichiometry: 1.0
species: 739499

782943
type: SpeciesReference
stoichiometry: 2.0
species: 741308

782883
type: SpeciesReference
stoichiometry: 1.0
species: 732465

782967
type: SpeciesReference
stoichiometry: 1.0
species: 739963

739963
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Glutamate 5-phosphate_C5H8NO7P

783063
type: SpeciesReference
stoichiometry: 2.0
species: 747123

782895
type: SpeciesReference
stoichiometry: 1.0
species: 730246

730246
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: N-Acetyl-L-glutamyl 5-phosphate_C7H9NO8P

783027
type: SpeciesReference
stoichiometry: 1.0
species: 744624

782919
type: SpeciesReference
stoichiometry: 3.0
species: 747002

782871
type: SpeciesReference
stoichiometry: 1.0
species: 740023

782907
type: SpeciesReference
stoichiometry: 1.0
species: 744712

782991
type: SpeciesReference
stoichiometry: 1.0
species: 740361

783087
type: SpeciesReference
stoichiometry: 3.0
species: 747062

783015
type: SpeciesReference
stoichiometry: 1.0
species: 730946

782835
type: SpeciesReference
stoichiometry: 1.0
species: 739963

783051
type: SpeciesReference
stoichiometry: 1.0
species: 744663

734259
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Creatine_C4H9N3O2

038719
type: Reaction
fast: false
reactant: 831174
reactant: 831150
product: 831222
product: 831210
product: 831198
is: http://identifiers.org/ec-code/4.4.1.1
notes: R_SELCYSTGL subsystem: Selenoamino acid metabolism R_SELCYSTGL equation: [c] : h2o + selcyst --> 2obut + nh4 + selcys R_CYSTGL subsystem: Cysteine Metabolism R_CYSTGL equation: [c] : cyst-L + h2o --> 2obut + cys-L + nh4
reversible: false
reactant: 831162
is: ENSCAFG00000020417.2
product: 831186

831174
type: SpeciesReference
stoichiometry: 2.0
species: 741151

831150
type: SpeciesReference
stoichiometry: 1.0
species: 735264

735264
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Cystathionine_C7H14N2O4S

831222
type: SpeciesReference
stoichiometry: 2.0
species: 747294

831210
type: SpeciesReference
stoichiometry: 1.0
species: 750986

750986
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Selenocysteine_C3H7NO2Se

831198
type: SpeciesReference
stoichiometry: 2.0
species: 727009

831162
type: SpeciesReference
stoichiometry: 1.0
species: 750998

831186
type: SpeciesReference
stoichiometry: 1.0
species: 735216

744534
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 9_C83H133N7O64S2X

726211
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _10-formyltetrahydrofolate-[Glu](6)_C45H51N12O22

031693
type: Reaction
reversible: false
product: 765368
notes: R_HGNTOR subsystem: Tyrosine metabolism R_HGNTOR equation: [c] : hgentis + o2 --> 4mlacac + h
name: Homogentisate:oxygen 1,2-oxidoreductase (decyclizing)
is: http://identifiers.org/ec-code/1.13.11.5
reactant: 765343
product: 765380
fast: false
reactant: 765356
is: ENSCAFG00000011254.2

765368
type: SpeciesReference
stoichiometry: 1.0
species: 728185

728185
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Maleylacetoacetate_C8H6O6

765343
type: SpeciesReference
stoichiometry: 1.0
species: 741741

765380
type: SpeciesReference
stoichiometry: 1.0
species: 741259

765356
type: SpeciesReference
stoichiometry: 1.0
species: 747698

753531
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Urocanate_C6H5N2O2

031825
type: Reaction
reactant: 767063
is: ENSCAFG00000009138.2
reactant: 767075
fast: false
reactant: 767051
product: 767087
name: dimethylglycine dehydrogenase, mitochondrial
product: 767099
notes: R_DMGDHm subsystem: Glycine, Serine, and Threonine Metabolism R_DMGDHm equation: [m] : dmgly + fad + h2o --> fadh2 + fald + sarcs
is: http://identifiers.org/ec-code/1.5.99.2
reversible: false
product: 767111

767063
type: SpeciesReference
stoichiometry: 1.0
species: 741199

767075
type: SpeciesReference
stoichiometry: 1.0
species: 738039

767051
type: SpeciesReference
stoichiometry: 1.0
species: 736656

736656
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: N,N-Dimethylglycine_C4H9NO2

767087
type: SpeciesReference
stoichiometry: 1.0
species: 738087

767099
type: SpeciesReference
stoichiometry: 1.0
species: 750878

767111
type: SpeciesReference
stoichiometry: 1.0
species: 738147

738147
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Formaldehyde_CH2O

737702
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: estradiol glucuronide_C24H32O8

726608
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _1 acyl phosphoglycerol_C6H13O7PFULLRCO2

731864
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Androsterone_C19H30O2

040899
type: Reaction
reversible: false
product: 853145
product: 853133
notes: R_SARDHm subsystem: Urea cycle/amino group metabolism R_SARDHm equation: [m] : fad + sarcs + thf --> fadh2 + gly + mlthf
is: ENSCAFG00000019794.2
product: 853157
is: http://identifiers.org/ec-code/1.5.99.1
reactant: 853097
name: Sarcosine dehydrogenase (m)
reactant: 853109
reactant: 853121
fast: false

853145
type: SpeciesReference
stoichiometry: 1.0
species: 740205

740205
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Glycine_C2H5NO2

853133
type: SpeciesReference
stoichiometry: 1.0
species: 738087

853157
type: SpeciesReference
stoichiometry: 1.0
species: 746617

746617
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _5,10-Methylenetetrahydrofolate_C20H21N7O6

853097
type: SpeciesReference
stoichiometry: 1.0
species: 750878

853109
type: SpeciesReference
stoichiometry: 1.0
species: 752374

752374
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _5,6,7,8-Tetrahydrofolate_C19H21N7O6

853121
type: SpeciesReference
stoichiometry: 1.0
species: 738039

727759
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053

751434
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Squalene_C30H50

037858
type: Reaction
product: 823262
reactant: 823226
fast: false
reversible: true
product: 823250
is: http://identifiers.org/ec-code/1.1.1.272
product: 823238
product: 823274
is: ENSCAFG00000013438.2
notes: R_SLDx subsystem: Cysteine Metabolism R_SLDx equation: [c] : nad + sl-L <==> 3spyr + h + nadh R_MDH subsystem: Citric Acid Cycle R_MDH equation: [c] : mal-L + nad <==> h + nadh + oaa
is: http://identifiers.org/ec-code/1.1.1.37
is: ENSCAFG00000003129.2
reactant: 823214
reactant: 823202

823262
type: SpeciesReference
stoichiometry: 2.0
species: 741259

823226
type: SpeciesReference
stoichiometry: 1.0
species: 751154

751154
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-sulfolactate_C3H4O6S

823250
type: SpeciesReference
stoichiometry: 1.0
species: 747830

747830
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Oxaloacetate_C4H2O5

823238
type: SpeciesReference
stoichiometry: 1.0
species: 727843

727843
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Sulfopyruvate_C3H2O6S

823274
type: SpeciesReference
stoichiometry: 2.0
species: 747050

823214
type: SpeciesReference
stoichiometry: 1.0
species: 745904

823202
type: SpeciesReference
stoichiometry: 2.0
species: 746978

734417
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Cortisol_C21H30O5

726319
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: _10-Formyltetrahydrofolate_C20H21N7O7

729822
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (S)-Squalene-2,3-epoxide_C30H50O

743733
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 16_C157H253N11O124S4X

033318
type: Reaction
reactant: 779965
is: ENSCAFG00000002064.2
reversible: true
product: 780001
reactant: 779977
fast: false
name: choline, sodium cotransport
notes: R_CHOLt4 subsystem: Transport, Extracellular R_CHOLt4 equation: chol[e] + na1[e] <==> chol[c] + na1[c]
product: 779989

779965
type: SpeciesReference
stoichiometry: 1.0
species: 746930

780001
type: SpeciesReference
stoichiometry: 1.0
species: 746918

779977
type: SpeciesReference
stoichiometry: 1.0
species: 733347

733347
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Choline_C5H14NO

779989
type: SpeciesReference
stoichiometry: 1.0
species: 733335

738834
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Fumarate_C4H2O4

030549
type: Reaction
is: http://identifiers.org/ec-code/3.1.3.7
product: 755634
reactant: 755598
product: 755646
reactant: 755622
reversible: false
product: 755658
reactant: 755610
is: ENSCAFG00000010927.2
fast: false
notes: R_BPNT2 subsystem: Nucleotides R_BPNT2 equation: [c] : h2o + paps --> aps + pi R_BPNT subsystem: Nucleotides R_BPNT equation: [c] : h2o + pap --> amp + pi

755634
type: SpeciesReference
stoichiometry: 2.0
species: 749200

755598
type: SpeciesReference
stoichiometry: 1.0
species: 748651

755646
type: SpeciesReference
stoichiometry: 1.0
species: 732044

755622
type: SpeciesReference
stoichiometry: 2.0
species: 741151

755658
type: SpeciesReference
stoichiometry: 1.0
species: 731755

755610
type: SpeciesReference
stoichiometry: 1.0
species: 748675

037267
type: Reaction
reactant: 816415
is: http://identifiers.org/ec-code/3.1.3.5
product: 816500
reactant: 816366
reactant: 816342
notes: R_NTD7l subsystem: Nucleic acid degradation R_NTD7l equation: [l] : amp + h2o --> adn + pi R_NTD9l subsystem: Nucleic acid degradation R_NTD9l equation: [l] : gmp + h2o --> gsn + pi R_NTD4l subsystem: Nucleic acid degradation R_NTD4l equation: [l] : cmp + h2o --> cytd + pi R_NTD3l subsystem: Nucleic acid degradation R_NTD3l equation: [l] : dcmp + h2o --> dcyt + pi R_NTD8l subsystem: Nucleic acid degradation R_NTD8l equation: [l] : dgmp + h2o --> dgsn + pi R_NTD2l subsystem: Nucleic acid degradation R_NTD2l equation: [l] : h2o + ump --> pi + uri R_LAPCOAl subsystem: CoA Catabolism R_LAPCOAl equation: [l] : coa + h2o --> dpcoa + pi R_NTD5l subsystem: Nucleic acid degradation R_NTD5l equation: [l] : dtmp + h2o --> pi + thymd R_3NTD7l subsystem: Nucleic acid degradation R_3NTD7l equation: [l] : 3amp + h2o --> adn + pi R_NTD6l subsystem: Nucleic acid degradation R_NTD6l equation: [l] : damp + h2o --> dad-2 + pi
reactant: 816452
is: ENSCAFG00000008833.2
fast: false
product: 816512
reactant: 816439
reactant: 816330
product: 816464
product: 816524
reversible: false
product: 816476
reactant: 816379
product: 816536
reactant: 816403
reactant: 816354
product: 816560
product: 816488
product: 816548
product: 816572
reactant: 816391
reactant: 816427

816415
type: SpeciesReference
stoichiometry: 1.0
species: 734079

734079
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Coenzyme A_C21H32N7O16P3S

816500
type: SpeciesReference
stoichiometry: 1.0
species: 753603

816366
type: SpeciesReference
stoichiometry: 1.0
species: 735613

735613
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: dCMP_C9H12N3O7P

816342
type: SpeciesReference
stoichiometry: 1.0
species: 731791

731791
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: AMP_C10H12N5O7P

816452
type: SpeciesReference
stoichiometry: 1.0
species: 735469

735469
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: dAMP_C10H12N5O6P

816512
type: SpeciesReference
stoichiometry: 1.0
species: 737043

737043
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Dephospho-CoA_C21H33N7O13P2S

816439
type: SpeciesReference
stoichiometry: 1.0
species: 727275

816330
type: SpeciesReference
stoichiometry: 1.0
species: 733896

733896
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: CMP_C9H12N3O8P

816464
type: SpeciesReference
stoichiometry: 10.0
species: 749237

749237
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Phosphate_HO4P

816524
type: SpeciesReference
stoichiometry: 1.0
species: 735300

735300
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Cytidine_C9H13N3O5

816476
type: SpeciesReference
stoichiometry: 1.0
species: 736036

736036
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Deoxyguanosine_C10H13N5O4

816379
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species: 740566

740566
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boundary condition: false
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initial amount: NaN
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name: GMP_C10H12N5O8P

816536
type: SpeciesReference
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species: 735757

816403
type: SpeciesReference
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species: 741187

816354
type: SpeciesReference
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species: 753435

816560
type: SpeciesReference
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species: 730886

730886
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Adenosine_C10H13N5O4

816488
type: SpeciesReference
stoichiometry: 1.0
species: 735360

735360
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Deoxyadenosine_C10H13N5O3

816548
type: SpeciesReference
stoichiometry: 1.0
species: 740775

816572
type: SpeciesReference
stoichiometry: 1.0
species: 752557

752557
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Thymidine_C10H14N2O5

816391
type: SpeciesReference
stoichiometry: 1.0
species: 735986

735986
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: dGMP_C10H12N5O7P

816427
type: SpeciesReference
stoichiometry: 1.0
species: 737163

038537
type: Reaction
reactant: 829818
reactant: 829794
reactant: 829806
reactant: 829782
fast: false
is: ENSCAFG00000008695.2
product: 829854
notes: R_PIK3 subsystem: Inositol Phosphate Metabolism R_PIK3 equation: [c] : atp + pail_hs --> adp + h + pail3p_hs R_PI5P3K subsystem: Inositol Phosphate Metabolism R_PI5P3K equation: [c] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI4P3K subsystem: Inositol Phosphate Metabolism R_PI4P3K equation: [c] : atp + pail4p_hs --> adp + h + pail34p_hs
is: ENSCAFG00000012564.2
product: 829830
product: 829842
product: 829866
product: 829878
reversible: false
is: http://identifiers.org/ec-code/2.7.1.137

829818
type: SpeciesReference
stoichiometry: 1.0
species: 748531

829794
type: SpeciesReference
stoichiometry: 3.0
species: 732441

829806
type: SpeciesReference
stoichiometry: 1.0
species: 748591

829782
type: SpeciesReference
stoichiometry: 1.0
species: 748567

829854
type: SpeciesReference
stoichiometry: 3.0
species: 730922

829830
type: SpeciesReference
stoichiometry: 1.0
species: 748459

829842
type: SpeciesReference
stoichiometry: 1.0
species: 748435

829866
type: SpeciesReference
stoichiometry: 1.0
species: 748483

829878
type: SpeciesReference
stoichiometry: 3.0
species: 741259

726404
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _12R-Hydroperoxyeicosatetraenoate_C20H31O4

732164
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: arachidonic acid_C20H31O2

031210
type: Reaction
fast: false
reversible: false
notes: R_CORE3GTg subsystem: O-Glycan Biosynthesis R_CORE3GTg equation: [g] : Tn_antigen + uacgam --> core3 + h + udp
product: 761343
is: ENSCAFG00000005189.2
name: Core 3 beta-GlcNAc-transferase, Golgi apparatus
product: 761355
reactant: 761319
is: http://identifiers.org/ec-code/2.4.1.147
product: 761331
reactant: 761307

761343
type: SpeciesReference
stoichiometry: 1.0
species: 741283

761355
type: SpeciesReference
stoichiometry: 1.0
species: 734163

734163
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Core 3_C16H27N2O10X

761319
type: SpeciesReference
stoichiometry: 1.0
species: 729858

761331
type: SpeciesReference
stoichiometry: 1.0
species: 753157

761307
type: SpeciesReference
stoichiometry: 1.0
species: 753121

034661
type: Reaction
reversible: true
is: ENSCAFG00000019667.2
is: ENSCAFG00000000212.2
reactant: 792269
name: glucose transport (uniport)
fast: false
notes: R_GLCt1r subsystem: Transport, Extracellular R_GLCt1r equation: glc-D[e] <==> glc-D[c]
product: 792281
is: ENSCAFG00000015634.2

792269
type: SpeciesReference
stoichiometry: 1.0
species: 739827

792281
type: SpeciesReference
stoichiometry: 1.0
species: 739815

031571
type: Reaction
product: 764492
reversible: true
is: ENSCAFG00000019451.2
reactant: 764444
reactant: 764456
is: ENSCAFG00000008647.2
fast: false
notes: R_TKT2 subsystem: Pentose Phosphate Pathway R_TKT2 equation: [c] : e4p + xu5p-D <==> f6p + g3p R_TKT1 subsystem: Pentose Phosphate Pathway R_TKT1 equation: [c] : r5p + xu5p-D <==> g3p + s7p
product: 764480
product: 764504
reactant: 764468
is: http://identifiers.org/ec-code/2.2.1.1

764492
type: SpeciesReference
stoichiometry: 1.0
species: 738015

764444
type: SpeciesReference
stoichiometry: 1.0
species: 737436

737436
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Erythrose 4-phosphate_C4H7O7P

764456
type: SpeciesReference
stoichiometry: 1.0
species: 750490

764480
type: SpeciesReference
stoichiometry: 2.0
species: 739003

764504
type: SpeciesReference
stoichiometry: 1.0
species: 750818

750818
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Sedoheptulose 7-phosphate_C7H13O10P

764468
type: SpeciesReference
stoichiometry: 2.0
species: 754257

754257
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Xylulose 5-phosphate_C5H9O8P

749658
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: glycophosphatidylinositol (GPI)-anchored protein precursor_XY

729549
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: R total 2 coenzyme A_CO2FULLR2C21H31N7O15P3S

030561
type: Reaction
is: ENSCAFG00000014303.2
is: http://identifiers.org/ec-code/2.1.2.3
reactant: 755695
is: http://identifiers.org/ec-code/3.5.4.10
reactant: 755670
product: 755731
fast: false
reversible: true
notes: R_IMPC subsystem: IMP Biosynthesis R_IMPC equation: [c] : h2o + imp <==> fprica R_AICART subsystem: IMP Biosynthesis R_AICART equation: [c] : 10fthf + aicar <==> fprica + thf
product: 755719
reactant: 755682
reactant: 755707

755695
type: SpeciesReference
stoichiometry: 1.0
species: 726295

726295
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _10-Formyltetrahydrofolate_C20H21N7O7

755670
type: SpeciesReference
stoichiometry: 1.0
species: 731345

755731
type: SpeciesReference
stoichiometry: 2.0
species: 738426

738426
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide_C10H13N4O9P

755719
type: SpeciesReference
stoichiometry: 1.0
species: 752337

755682
type: SpeciesReference
stoichiometry: 1.0
species: 741151

755707
type: SpeciesReference
stoichiometry: 1.0
species: 742843

040417
type: Reaction
product: 847143
reactant: 846900
product: 846936
reactant: 846742
notes: R_S6TASE23ly subsystem: Keratan sulfate degradation R_S6TASE23ly equation: [l] : h2o + ksii_core2_deg3 <==> h + ksii_core2_deg4 + so4 R_S6TASE15ly subsystem: Keratan sulfate degradation R_S6TASE15ly equation: [l] : h2o + ksi_deg18 <==> h + ksi_deg19 + so4 R_S6TASE13ly subsystem: Keratan sulfate degradation R_S6TASE13ly equation: [l] : h2o + ksi_deg12 <==> h + ksi_deg13 + so4 R_S6TASE26ly subsystem: Keratan sulfate degradation R_S6TASE26ly equation: [l] : h2o + ksii_core4_deg3 <==> h + ksii_core4_deg4 + so4 R_S6TASE12ly subsystem: Keratan sulfate degradation R_S6TASE12ly equation: [l] : h2o + ksi_deg9 <==> h + ksi_deg10 + so4 R_S6TASE20ly subsystem: Keratan sulfate degradation R_S6TASE20ly equation: [l] : h2o + ksi_deg33 <==> h + ksi_deg34 + so4 R_S6TASE17ly subsystem: Keratan sulfate degradation R_S6TASE17ly equation: [l] : h2o + ksi_deg24 <==> h + ksi_deg25 + so4 R_S6TASE21ly subsystem: Keratan sulfate degradation R_S6TASE21ly equation: [l] : h2o + ksi_deg36 <==> h + ksi_deg37 + so4 R_S6TASE11ly subsystem: Keratan sulfate degradation R_S6TASE11ly equation: [l] : h2o + ksi_deg6 <==> h + ksi_deg7 + so4 R_S6TASE3ly subsystem: Heparan sulfate degradation R_S6TASE3ly equation: [l] : h2o + hs_deg11 <==> h + hs_deg12 + so4 R_S6TASE1ly subsystem: Heparan sulfate degradation R_S6TASE1ly equation: [l] : h2o + hs <==> h + hs_deg1 + so4 R_S6TASE24ly subsystem: Keratan sulfate degradation R_S6TASE24ly equation: [l] : h2o + ksii_core2_deg6 <==> h + ksii_core2_deg7 + so4 R_S6TASE2ly subsystem: Heparan sulfate degradation R_S6TASE2ly equation: [l] : h2o + hs_deg5 <==> h + hs_deg6 + so4 R_S6TASE16ly subsystem: Keratan sulfate degradation R_S6TASE16ly equation: [l] : h2o + ksi_deg21 <==> h + ksi_deg22 + so4 R_S6TASE14ly subsystem: Keratan sulfate degradation R_S6TASE14ly equation: [l] : h2o + ksi_deg15 <==> h + ksi_deg16 + so4 R_S6TASE19ly subsystem: Keratan sulfate degradation R_S6TASE19ly equation: [l] : h2o + ksi_deg30 <==> h + ksi_deg31 + so4 R_S6TASE18ly subsystem: Keratan sulf…
product: 847068
reactant: 846730
reactant: 846804
reactant: 846852
product: 846984
reactant: 846840
product: 847104
product: 846924
product: 847080
product: 847092
product: 847032
is: http://identifiers.org/ec-code/3.1.6.14
product: 847117
reactant: 846779
product: 846948
reactant: 846767
product: 846996
is: ENSCAFG00000000359.2
reactant: 846791
product: 847044
product: 847056
reactant: 846888
fast: false
product: 846972
reactant: 846718
reactant: 846706
reactant: 846754
reactant: 846876
reactant: 846828
product: 847020
reversible: true
product: 847008
product: 847130
reactant: 846816
reactant: 846864
reactant: 846912
product: 846960

847143
type: SpeciesReference
stoichiometry: 1.0
species: 743228

846900
type: SpeciesReference
stoichiometry: 1.0
species: 743432

846936
type: SpeciesReference
stoichiometry: 17.0
species: 751227

846742
type: SpeciesReference
stoichiometry: 1.0
species: 743216

847068
type: SpeciesReference
stoichiometry: 1.0
species: 744386

846730
type: SpeciesReference
stoichiometry: 1.0
species: 744374

846804
type: SpeciesReference
stoichiometry: 1.0
species: 743612

846852
type: SpeciesReference
stoichiometry: 1.0
species: 743348

846984
type: SpeciesReference
stoichiometry: 1.0
species: 743444

846840
type: SpeciesReference
stoichiometry: 1.0
species: 744121

847104
type: SpeciesReference
stoichiometry: 1.0
species: 743480

846924
type: SpeciesReference
stoichiometry: 1.0
species: 743156

847080
type: SpeciesReference
stoichiometry: 1.0
species: 742019

742019
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 12_C55H82N3O64S6

847092
type: SpeciesReference
stoichiometry: 1.0
species: 742248

742248
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 6_C67H98N4O83S9

847032
type: SpeciesReference
stoichiometry: 1.0
species: 743408

847117
type: SpeciesReference
stoichiometry: 1.0
species: 744169

846779
type: SpeciesReference
stoichiometry: 1.0
species: 743144

846948
type: SpeciesReference
stoichiometry: 1.0
species: 743360

846767
type: SpeciesReference
stoichiometry: 1.0
species: 743312

846996
type: SpeciesReference
stoichiometry: 1.0
species: 743120

846791
type: SpeciesReference
stoichiometry: 17.0
species: 741187

847044
type: SpeciesReference
stoichiometry: 1.0
species: 743192

847056
type: SpeciesReference
stoichiometry: 1.0
species: 744133

846888
type: SpeciesReference
stoichiometry: 1.0
species: 743276

846972
type: SpeciesReference
stoichiometry: 1.0
species: 743588

846718
type: SpeciesReference
stoichiometry: 1.0
species: 742007

742007
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 11_C55H81N3O67S7

846706
type: SpeciesReference
stoichiometry: 1.0
species: 742236

742236
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 5_C67H97N4O86S10

846754
type: SpeciesReference
stoichiometry: 1.0
species: 744157

846876
type: SpeciesReference
stoichiometry: 1.0
species: 743396

846828
type: SpeciesReference
stoichiometry: 1.0
species: 743180

847020
type: SpeciesReference
stoichiometry: 1.0
species: 742115

742115
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 1_C79H115N5O99S11

847008
type: SpeciesReference
stoichiometry: 17.0
species: 741296

847130
type: SpeciesReference
stoichiometry: 1.0
species: 743324

846816
type: SpeciesReference
stoichiometry: 1.0
species: 743468

846864
type: SpeciesReference
stoichiometry: 1.0
species: 742296

742296
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, free chain_C79H114N5O102S12

846912
type: SpeciesReference
stoichiometry: 1.0
species: 743576

846960
type: SpeciesReference
stoichiometry: 1.0
species: 743288

032787
type: Reaction
fast: false
product: 776356
reactant: 776320
product: 776381
is: ENSCAFG00000016814.2
reversible: true
reactant: 776308
notes: R_PDX5PO subsystem: Vitamin B6 Metabolism R_PDX5PO equation: [c] : o2 + pdx5p <==> h2o2 + pydx5p R_PYAM5POr subsystem: Vitamin B6 Metabolism R_PYAM5POr equation: [c] : h2o + o2 + pyam5p <==> h2o2 + nh4 + pydx5p
product: 776368
reactant: 776332
reactant: 776344
is: http://identifiers.org/ec-code/1.4.3.5

776356
type: SpeciesReference
stoichiometry: 1.0
species: 747294

776320
type: SpeciesReference
stoichiometry: 1.0
species: 750285

750285
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Pyridoxamine 5'-phosphate_C8H12N2O5P

776381
type: SpeciesReference
stoichiometry: 2.0
species: 750309

750309
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Pyridoxal 5'-phosphate_C8H8NO6P

776308
type: SpeciesReference
stoichiometry: 1.0
species: 748834

748834
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Pyridoxine 5'-phosphate_C8H10NO6P

776368
type: SpeciesReference
stoichiometry: 2.0
species: 741078

776332
type: SpeciesReference
stoichiometry: 1.0
species: 741151

776344
type: SpeciesReference
stoichiometry: 2.0
species: 747698

752410
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Thiamin monophosphate_C12H16N4O4PS

030525
type: Reaction
name: Hydroxymethylglutaryl CoA synthase (ir)
reactant: 755417
notes: R_HMGCOASi subsystem: Cholesterol Metabolism R_HMGCOASi equation: [c] : aacoa + accoa + h2o --> coa + h + hmgcoa
is: ENSCAFG00000018572.2
reactant: 755405
reactant: 755393
fast: false
reversible: false
product: 755441
product: 755453
product: 755429
is: http://identifiers.org/ec-code/4.1.3.5

755417
type: SpeciesReference
stoichiometry: 1.0
species: 729907

755405
type: SpeciesReference
stoichiometry: 1.0
species: 741151

755393
type: SpeciesReference
stoichiometry: 1.0
species: 730124

755441
type: SpeciesReference
stoichiometry: 1.0
species: 741814

741814
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053

755453
type: SpeciesReference
stoichiometry: 1.0
species: 741259

755429
type: SpeciesReference
stoichiometry: 1.0
species: 734054

729675
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: R total_CO2FULLR

035876
type: Reaction
fast: false
is: ENSCAFG00000007098.2
reactant: 803604
notes: R_P4507A1r subsystem: Bile Acid Biosynthesis R_P4507A1r equation: [r] : chsterol + h + nadph + o2 --> h2o + nadp + xol7a
product: 803664
reactant: 803592
name: cytochrome P450, family 7, subfamily A, polypeptide 1
product: 803652
product: 803640
is: http://identifiers.org/ec-code/1.14.13.17
reversible: false
reactant: 803616
reactant: 803628

803604
type: SpeciesReference
stoichiometry: 1.0
species: 733618

733618
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Cholesterol_C27H46O

803664
type: SpeciesReference
stoichiometry: 1.0
species: 747148

803592
type: SpeciesReference
stoichiometry: 1.0
species: 747746

803652
type: SpeciesReference
stoichiometry: 1.0
species: 741223

803640
type: SpeciesReference
stoichiometry: 1.0
species: 753955

753955
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _7 alpha-Hydroxycholesterol_C27H46O2

803616
type: SpeciesReference
stoichiometry: 1.0
species: 747209

803628
type: SpeciesReference
stoichiometry: 1.0
species: 741332

038816
type: Reaction
reactant: 831763
reactant: 831751
notes: R_CRNtuIR subsystem: Transport, Extracellular R_CRNtuIR equation: crn[e] --> crn[c] R_CRNtHa subsystem: Transport, Extracellular R_CRNtHa equation: crn[c] + h[e] --> crn[e] + h[c]
product: 831775
reactant: 831739
reversible: false
is: ENSCAFG00000000840.2
product: 831787
fast: false
product: 831799

831763
type: SpeciesReference
stoichiometry: 1.0
species: 734345

831751
type: SpeciesReference
stoichiometry: 1.0
species: 734357

734357
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Carnitine_C7H15NO3

831775
type: SpeciesReference
stoichiometry: 1.0
species: 734357

831739
type: SpeciesReference
stoichiometry: 1.0
species: 741271

831787
type: SpeciesReference
stoichiometry: 1.0
species: 734345

831799
type: SpeciesReference
stoichiometry: 1.0
species: 741259

032487
type: Reaction
reactant: 773231
product: 773331
reactant: 773294
is: ENSCAFG00000020420.2
is: http://identifiers.org/ec-code/2.7.1.21
product: 773355
product: 773379
product: 773307
reactant: 773244
product: 773391
reactant: 773282
reactant: 773270
reactant: 773257
notes: R_DURIK1m subsystem: Nucleotides R_DURIK1m equation: [m] : atp + duri --> adp + dump + h R_TMDK1 subsystem: Nucleotides R_TMDK1 equation: [c] : atp + thymd --> adp + dtmp + h R_DURIK1 subsystem: Nucleotides R_DURIK1 equation: [c] : atp + duri --> adp + dump + h R_TMDK1m subsystem: Nucleotides R_TMDK1m equation: [m] : atp + thymd --> adp + dtmp + h
product: 773343
reversible: false
fast: false
product: 773367
product: 773319

773231
type: SpeciesReference
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species: 737326

773331
type: SpeciesReference
stoichiometry: 1.0
species: 737290

773294
type: SpeciesReference
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species: 732465

773355
type: SpeciesReference
stoichiometry: 1.0
species: 737151

773379
type: SpeciesReference
stoichiometry: 2.0
species: 741259

773307
type: SpeciesReference
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species: 737176

737176
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: dTMP_C10H13N2O8P

773244
type: SpeciesReference
stoichiometry: 1.0
species: 737338

773391
type: SpeciesReference
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species: 741308

773282
type: SpeciesReference
stoichiometry: 1.0
species: 752533

773270
type: SpeciesReference
stoichiometry: 2.0
species: 732441

773257
type: SpeciesReference
stoichiometry: 1.0
species: 752569

773343
type: SpeciesReference
stoichiometry: 2.0
species: 730922

773367
type: SpeciesReference
stoichiometry: 1.0
species: 737302

737302
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: dUMP_C9H11N2O8P

773319
type: SpeciesReference
stoichiometry: 2.0
species: 730946

741488
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Hexadecanoate (n-C16:0)_C16H31O2

742212
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 3_C81H117N5O97S10

035227
type: Reaction
reactant: 797578
reversible: true
reactant: 797590
product: 797650
is: http://identifiers.org/ec-code/2.7.1.107
is: ENSCAFG00000009248.2
is: ENSCAFG00000003373.2
product: 797674
product: 797638
reactant: 797614
reactant: 797602
fast: false
notes: R_DAGK_hs subsystem: Glycerophospholipid Metabolism R_DAGK_hs equation: [c] : atp + dag_hs <==> adp + h + pa_hs R_DAGKn_hs subsystem: Glycerophospholipid Metabolism R_DAGKn_hs equation: [n] : atp + dag_hs <==> adp + h + pa_hs
product: 797686
product: 797662
product: 797626

797578
type: SpeciesReference
stoichiometry: 1.0
species: 735409

797590
type: SpeciesReference
stoichiometry: 1.0
species: 732441

797650
type: SpeciesReference
stoichiometry: 1.0
species: 748302

797674
type: SpeciesReference
stoichiometry: 1.0
species: 730958

797638
type: SpeciesReference
stoichiometry: 1.0
species: 741320

797614
type: SpeciesReference
stoichiometry: 1.0
species: 732477

797602
type: SpeciesReference
stoichiometry: 1.0
species: 735433

735433
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2

797686
type: SpeciesReference
stoichiometry: 1.0
species: 741259

797662
type: SpeciesReference
stoichiometry: 1.0
species: 730922

797626
type: SpeciesReference
stoichiometry: 1.0
species: 748338

748338
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

740603
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GlcNAc-alpha-1,4-Core 2_C30H50N3O20X

736728
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dimethylallyl diphosphate_C5H9O7P2

751178
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Sulfite_O3S

744459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 3_C55H89N5O38X

031681
type: Reaction
reversible: false
fast: false
is: ENSCAFG00000018753.2
is: ENSCAFG00000005861.2
notes: R_NADH2_DASH_u10m subsystem: Oxidative Phosphorylation R_NADH2_DASH_u10m equation: (5) h[m] + nadh[m] + q10[m] --> (4) h[c] + nad[m] + q10h2[m]
is: ENSCAFG00000010193.2
is: http://identifiers.org/ec-code/1.6.99.3
is: ENSCAFG00000008411.2
is: ENSCAFG00000018686.2
is: ENSCAFG00000012591.2
is: ENSCAFG00000014244.2
is: ENSCAFG00000016258.2
is: ENSCAFG00000017259.2
is: ENSCAFG00000010508.2
is: ENSCAFG00000001045.2
is: ENSCAFG00000020282.2
is: ENSCAFG00000003134.2
is: ENSCAFG00000003185.2
is: ENSCAFG00000003930.2
is: ENSCAFG00000009698.2
reactant: 765269
is: ENSCAFG00000010903.2
is: ENSCAFG00000017667.2
product: 765319
is: ENSCAFG00000015306.1
is: ENSCAFG00000012850.2
is: ENSCAFG00000011083.2
is: ENSCAFG00000000982.2
product: 765331
product: 765307
reactant: 765282
name: NADH dehydrogenase, mitochondrial
is: ENSCAFG00000012111.2
is: ENSCAFG00000011204.2
is: ENSCAFG00000006232.2
is: ENSCAFG00000019476.2
is: ENSCAFG00000015320.2
is: ENSCAFG00000006815.2
is: ENSCAFG00000018399.2
is: ENSCAFG00000003724.2
is: ENSCAFG00000011109.2
is: ENSCAFG00000004842.2
is: ENSCAFG00000018497.2
is: ENSCAFG00000013333.2
reactant: 765295
is: ENSCAFG00000010444.2

765269
type: SpeciesReference
stoichiometry: 1.0
species: 750429

750429
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Ubiquinone-10_C59H90O4

765319
type: SpeciesReference
stoichiometry: 1.0
species: 747002

765331
type: SpeciesReference
stoichiometry: 4.0
species: 741259

765307
type: SpeciesReference
stoichiometry: 1.0
species: 750454

750454
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Ubiquinol-10_C59H92O4

765282
type: SpeciesReference
stoichiometry: 5.0
species: 741308

765295
type: SpeciesReference
stoichiometry: 1.0
species: 747062

753459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: UMP_C9H11N2O9P

726476
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _13-cis-retinoyl glucuronide_C26H35O8

031077
type: Reaction
is: ENSCAFG00000017384.2
is: http://identifiers.org/ec-code/2.7.1.107
product: 760394
is: ENSCAFG00000024940.1
name: Diacylglycerol phosphate kinase (homo sapiens)
product: 760382
reactant: 760358
is: ENSCAFG00000016708.2
is: ENSCAFG00000000852.2
reactant: 760370
notes: R_DAGK_hs subsystem: Glycerophospholipid Metabolism R_DAGK_hs equation: [c] : atp + dag_hs <==> adp + h + pa_hs
is: ENSCAFG00000013503.2
product: 760406
fast: false
is: ENSCAFG00000000078.2
reversible: true
is: ENSCAFG00000011816.2
is: ENSCAFG00000004733.2

760394
type: SpeciesReference
stoichiometry: 1.0
species: 741259

760382
type: SpeciesReference
stoichiometry: 1.0
species: 730922

760358
type: SpeciesReference
stoichiometry: 1.0
species: 735409

760370
type: SpeciesReference
stoichiometry: 1.0
species: 732441

760406
type: SpeciesReference
stoichiometry: 1.0
species: 748302

729162
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: heptaglutamyl folate (THF)_C49H57N13O24

736413
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (S)-Dihydroorotate_C5H5N2O4

731369
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1-alkyl 2-lysoglycerol 3-phosphocholine_C10H21O5NPFULLR

040717
type: Reaction
reactant: 851285
notes: R_GPIDAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIDAer equation: [r] : gpi_prot_hs + h2o --> dgpi_prot_hs + h + hdca R_GPIDA2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIDA2er equation: [r] : em2emgacpail_prot_hs + h2o --> dem2emgacpail_prot_hs + h + hdca
fast: false
is: ENSCAFG00000010742.2
product: 851311
reversible: false
product: 851337
product: 851298
reactant: 851273
product: 851324
reactant: 851261

851285
type: SpeciesReference
stoichiometry: 1.0
species: 737630

737630
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065

851311
type: SpeciesReference
stoichiometry: 1.0
species: 735901

735901
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065

851337
type: SpeciesReference
stoichiometry: 2.0
species: 741332

851298
type: SpeciesReference
stoichiometry: 2.0
species: 741500

741500
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Hexadecanoate (n-C16:0)_C16H31O2

851273
type: SpeciesReference
stoichiometry: 1.0
species: 740663

740663
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: glycophosphatidylinositol (GPI)-anchored protein_C55H106N4O38P4FULLRCO2FULLR2CO2X

851324
type: SpeciesReference
stoichiometry: 1.0
species: 736011

736011
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: deacylated-glycophosphatidylinositol (GPI)-anchored protein_C39H76N4O37P4FULLRCO2FULLR2CO2X

851261
type: SpeciesReference
stoichiometry: 2.0
species: 741223

746545
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1D-myo-Inositol 3,4-bisphosphate_C6H10O12P2

031090
type: Reaction
reactant: 760418
is: http://identifiers.org/ec-code/2.5.1.6
is: ENSCAFG00000017181.2
reactant: 760454
reactant: 760442
is: ENSCAFG00000015807.2
product: 760466
reactant: 760430
product: 760490
reversible: false
fast: false
product: 760502
notes: R_METAT subsystem: Methionine Metabolism R_METAT equation: [c] : atp + h2o + met-L --> amet + pi + ppi R_SELMETAT subsystem: Selenoamino acid metabolism R_SELMETAT equation: [c] : atp + h2o + selmeth --> pi + ppi + seasmet
is: ENSCAFG00000007755.1
product: 760478

760418
type: SpeciesReference
stoichiometry: 1.0
species: 746291

760454
type: SpeciesReference
stoichiometry: 1.0
species: 751022

751022
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Selenomethionine_C5H11NO2Se

760442
type: SpeciesReference
stoichiometry: 2.0
species: 732441

760466
type: SpeciesReference
stoichiometry: 2.0
species: 749200

760430
type: SpeciesReference
stoichiometry: 2.0
species: 741151

760490
type: SpeciesReference
stoichiometry: 1.0
species: 731694

760502
type: SpeciesReference
stoichiometry: 2.0
species: 749466

760478
type: SpeciesReference
stoichiometry: 1.0
species: 750938

750938
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Se-Adenosylselenomethionine_C15H23N6O5Se

039020
type: Reaction
is: http://identifiers.org/ec-code/2.7.7.15
product: 833506
reactant: 833470
fast: false
reactant: 833482
product: 833518
notes: R_CHLPCTD subsystem: Glycerophospholipid Metabolism R_CHLPCTD equation: [c] : cholp + ctp + h --> cdpchol + ppi R_CPCTDTX subsystem: Glycerophospholipid Metabolism R_CPCTDTX equation: [c] : ctp + h + ntm2amep --> cmpntm2amep + ppi
reversible: false
reactant: 833494
is: ENSCAFG00000013493.2
product: 833530
is: ENSCAFG00000012967.2
reactant: 833458

833506
type: SpeciesReference
stoichiometry: 1.0
species: 733226

833470
type: SpeciesReference
stoichiometry: 1.0
species: 747674

833482
type: SpeciesReference
stoichiometry: 2.0
species: 741259

833518
type: SpeciesReference
stoichiometry: 1.0
species: 733957

733957
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053

833494
type: SpeciesReference
stoichiometry: 2.0
species: 735155

833530
type: SpeciesReference
stoichiometry: 2.0
species: 749466

833458
type: SpeciesReference
stoichiometry: 1.0
species: 733516

036760
type: Reaction
product: 811698
reactant: 811626
reactant: 811602
is: ENSCAFG00000006150.2
notes: R_PNTK subsystem: CoA Biosynthesis R_PNTK equation: [c] : atp + pnto-R --> 4ppan + adp + h R_PNTKm subsystem: CoA Biosynthesis R_PNTKm equation: [m] : atp + pnto-R --> 4ppan + adp + h
is: http://identifiers.org/ec-code/2.7.1.33
product: 811650
product: 811662
reactant: 811614
fast: false
product: 811686
reversible: false
product: 811674
reactant: 811590
product: 811638

811698
type: SpeciesReference
stoichiometry: 1.0
species: 741259

811626
type: SpeciesReference
stoichiometry: 1.0
species: 732465

811602
type: SpeciesReference
stoichiometry: 1.0
species: 732441

811650
type: SpeciesReference
stoichiometry: 1.0
species: 730946

811662
type: SpeciesReference
stoichiometry: 1.0
species: 730922

811614
type: SpeciesReference
stoichiometry: 1.0
species: 749382

749382
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: (R)-Pantothenate_C9H16NO5

811686
type: SpeciesReference
stoichiometry: 1.0
species: 741308

811674
type: SpeciesReference
stoichiometry: 1.0
species: 728293

811590
type: SpeciesReference
stoichiometry: 1.0
species: 749358

811638
type: SpeciesReference
stoichiometry: 1.0
species: 728305

728305
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: D-4'-Phosphopantothenate_C9H15NO8P

735083
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Cytosine_C4H5N3O

032005
type: Reaction
product: 769011
reactant: 768939
product: 769047
is: ENSCAFG00000002500.2
reactant: 768951
reactant: 768975
notes: R_GALt1r subsystem: Transport, Extracellular R_GALt1r equation: gal[e] <==> gal[c] R_GAMt1r subsystem: Transport, Extracellular R_GAMt1r equation: gam[e] <==> gam[c] R_GLCt1r subsystem: Transport, Extracellular R_GLCt1r equation: glc-D[e] <==> glc-D[c] R_DHAAt1r subsystem: Transport, Extracellular R_DHAAt1r equation: dhdascb[e] <==> dhdascb[c] R_MANt1r subsystem: Transport, Extracellular R_MANt1r equation: man[e] <==> man[c] R_GLCtg subsystem: Transport, Golgi Apparatus R_GLCtg equation: glc-D[c] <==> glc-D[g]
reactant: 768987
reactant: 768963
fast: false
product: 769023
reversible: true
product: 769059
product: 769071
reactant: 768999
product: 769035

769011
type: SpeciesReference
stoichiometry: 1.0
species: 736243

768939
type: SpeciesReference
stoichiometry: 1.0
species: 746074

746074
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: D-Mannose_C6H12O6

769047
type: SpeciesReference
stoichiometry: 1.0
species: 739123

768951
type: SpeciesReference
stoichiometry: 1.0
species: 739135

768975
type: SpeciesReference
stoichiometry: 1.0
species: 736255

736255
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Dehydroascorbate_C6H6O6

768987
type: SpeciesReference
stoichiometry: 1.0
species: 739438

739438
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: D-Glucosamine_C6H14NO5

768963
type: SpeciesReference
stoichiometry: 1.0
species: 739827

769023
type: SpeciesReference
stoichiometry: 1.0
species: 746061

746061
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Mannose_C6H12O6

769059
type: SpeciesReference
stoichiometry: 1.0
species: 739426

739426
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Glucosamine_C6H14NO5

769071
type: SpeciesReference
stoichiometry: 1.0
species: 739815

768999
type: SpeciesReference
stoichiometry: 1.0
species: 739815

769035
type: SpeciesReference
stoichiometry: 1.0
species: 739839

739839
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: D-Glucose_C6H12O6

747282
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Formylanthranilate_C8H6NO3

034745
type: Reaction
fast: false
product: 792811
reactant: 792727
reactant: 792715
product: 792799
reactant: 792739
product: 792835
product: 792823
is: ENSCAFG00000000083.2
notes: R_H6_APOS_ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6_APOS_ETer equation: [r] : em3gacpail_hs + pe_hs --> dag_hs + em2emgacpail_hs R_H3ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3ETer equation: [r] : m2gacpail_hs + pe_hs --> dag_hs + memgacpail_hs R_H4ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H4ETer equation: [r] : m3gacpail_hs + pe_hs --> dag_hs + m2emgacpail_hs R_H7_APOS_ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7_APOS_ETer equation: [r] : emem2gacpail_hs + pe_hs --> dag_hs + gpi_hs R_H2ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H2ETer equation: [r] : mgacpail_hs + pe_hs --> dag_hs + emgacpail_hs
reactant: 792763
reactant: 792751
product: 792787
reversible: false
product: 792847
reactant: 792775

792811
type: SpeciesReference
stoichiometry: 1.0
species: 740651

792727
type: SpeciesReference
stoichiometry: 1.0
species: 745531

745531
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: trimannosyl-glucosaminyl-acylphosphatidylinositol (H4)_C49H88NO29PFULLRCO2FULLR2CO2

792715
type: SpeciesReference
stoichiometry: 1.0
species: 737642

792799
type: SpeciesReference
stoichiometry: 1.0
species: 737618

792739
type: SpeciesReference
stoichiometry: 1.0
species: 737654

792835
type: SpeciesReference
stoichiometry: 1.0
species: 745471

745471
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (dimannosyl),(phosphoethanolaminyl)-mannosyl-glucosylaminyl-acylphosphatidylinositol (H6)_C51H94N2O32P2FULLRCO2FULLR2CO2

792823
type: SpeciesReference
stoichiometry: 5.0
species: 735445

792763
type: SpeciesReference
stoichiometry: 5.0
species: 748886

792751
type: SpeciesReference
stoichiometry: 1.0
species: 745483

745483
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: dimannosyl-glucosaminyl-acylphosphatidylinositol (H3)_C43H78NO24PFULLRCO2FULLR2CO2

792787
type: SpeciesReference
stoichiometry: 1.0
species: 746170

746170
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (mannosyl),(phosphoethanolaminyl)-mannosyl-glucosylaminyl-acylphosphatidylinositol (B)_C45H84N2O27P2FULLRCO2FULLR2CO2

792847
type: SpeciesReference
stoichiometry: 1.0
species: 737666

737666
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: phosphoethanolaminyl-mannosyl-glucosylaminyl-acylphosphatidylinositol (H5)_C39H74N2O22P2FULLRCO2FULLR2CO2

792775
type: SpeciesReference
stoichiometry: 1.0
species: 746364

746364
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: mannosyl-glucosaminyl-acylphosphatidylinositiol (H2)_C37H68NO19PFULLRCO2FULLR2CO2

726656
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-1-Pyrroline-3-hydroxy-5-carboxylate_C5H6NO3

753979
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3alpha,7alpha-Dihydroxy-5beta-cholestane_C27H48O2

728015
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _4-Aminobutanoate_C4H9NO2

033925
type: Reaction
reactant: 785079
reactant: 785067
product: 785103
product: 785091
reactant: 785031
is: ENSCAFG00000005370.2
reversible: false
product: 785115
product: 785127
reactant: 785043
reactant: 785055
notes: R_P4508B13r subsystem: Bile Acid Biosynthesis R_P4508B13r equation: [r] : h + nadh + o2 + xol7aone --> h2o + nad + xoldiolone R_P4508B11r subsystem: Bile Acid Biosynthesis R_P4508B11r equation: [r] : h + nadph + o2 + xol7aone --> h2o + nadp + xoldiolone
fast: false

785079
type: SpeciesReference
stoichiometry: 2.0
species: 741332

785067
type: SpeciesReference
stoichiometry: 1.0
species: 747209

785103
type: SpeciesReference
stoichiometry: 1.0
species: 747148

785091
type: SpeciesReference
stoichiometry: 2.0
species: 741223

785031
type: SpeciesReference
stoichiometry: 2.0
species: 747746

785115
type: SpeciesReference
stoichiometry: 2.0
species: 754063

754063
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _7alpha,12alpha-Dihydroxycholest-4-en-3-one_C27H44O3

785127
type: SpeciesReference
stoichiometry: 1.0
species: 747026

785043
type: SpeciesReference
stoichiometry: 2.0
species: 754039

754039
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _7alpha-Hydroxycholest-4-en-3-one_C27H44O2

785055
type: SpeciesReference
stoichiometry: 1.0
species: 747074

747074
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

031355
type: Reaction
product: 762844
reactant: 762711
reactant: 762784
reactant: 762651
product: 762931
product: 762870
reactant: 762735
reactant: 762687
product: 762992
reactant: 762639
reactant: 762832
product: 762882
reactant: 762675
product: 762894
fast: false
is: ENSCAFG00000018266.2
product: 762857
reactant: 762808
product: 762944
product: 762907
reactant: 762772
product: 762919
product: 763004
product: 763016
product: 762980
product: 762956
reactant: 762723
product: 762968
reactant: 762627
reactant: 762820
reactant: 762796
reactant: 762663
reactant: 762747
reversible: false
product: 763053
reactant: 762699
notes: R_VALt4 subsystem: Transport, Extracellular R_VALt4 equation: na1[e] + val-L[e] --> na1[c] + val-L[c] R_THRt4 subsystem: Transport, Extracellular R_THRt4 equation: na1[e] + thr-L[e] --> na1[c] + thr-L[c] R_ILEt4 subsystem: Transport, Extracellular R_ILEt4 equation: ile-L[e] + na1[e] --> ile-L[c] + na1[c] R_METt4 subsystem: Transport, Extracellular R_METt4 equation: met-L[e] + na1[e] --> met-L[c] + na1[c] R_HISt4 subsystem: Transport, Extracellular R_HISt4 equation: his-L[e] + na1[e] --> his-L[c] + na1[c] R_LEUt4 subsystem: Transport, Extracellular R_LEUt4 equation: leu-L[e] + na1[e] --> leu-L[c] + na1[c] R_SERt4 subsystem: Transport, Extracellular R_SERt4 equation: na1[e] + ser-L[e] --> na1[c] + ser-L[c] R_ALAt4 subsystem: Transport, Extracellular R_ALAt4 equation: ala-L[e] + na1[e] --> ala-L[c] + na1[c] R_TYRt4 subsystem: Transport, Extracellular R_TYRt4 equation: na1[e] + tyr-L[e] --> na1[c] + tyr-L[c] R_CYSt4 subsystem: Transport, Extracellular R_CYSt4 equation: cys-L[e] + na1[e] --> cys-L[c] + na1[c] R_ARGt4 subsystem: Transport, Extracellular R_ARGt4 equation: arg-L[e] + na1[e] --> arg-L[c] + na1[c] R_ASNt4 subsystem: Transport, Extracellular R_ASNt4 equation: asn-L[e] + na1[e] --> asn-L[c] + na1[c] R_TRPt4 subsystem: Transport, Extracellular R_TRPt4 equation: na1[e] + trp-L[e] --> na1[c] + trp-L[c] R_GLYt4 subsystem: Transport, Extracellular R_GLYt4 equation: gly[e] + na1[e] --> gly[c] + na1[c] R_PHEt4 subsystem: Transport, Extracellular R_PHEt4 equation: na1[e] + phe-L[e] --> na1[c] + phe-L[c] R_GLNt4 subsystem: Transport, Extracellular R_GLNt4 equation: gln-L[e] + na1[e] --> gln-L[c] + na1[c] R_LYSt4 subsystem: Transport, Extracellular R_LYSt4 equation: lys-L[e] + na1[e] --> lys-L[c] + na1[c]
reactant: 762760
product: 763041
product: 763028

762844
type: SpeciesReference
stoichiometry: 1.0
species: 732332

762711
type: SpeciesReference
stoichiometry: 1.0
species: 744796

762784
type: SpeciesReference
stoichiometry: 1.0
species: 746303

762651
type: SpeciesReference
stoichiometry: 1.0
species: 745411

762931
type: SpeciesReference
stoichiometry: 1.0
species: 746291

762870
type: SpeciesReference
stoichiometry: 1.0
species: 745399

762735
type: SpeciesReference
stoichiometry: 1.0
species: 731561

762687
type: SpeciesReference
stoichiometry: 1.0
species: 752496

762992
type: SpeciesReference
stoichiometry: 1.0
species: 742758

762639
type: SpeciesReference
stoichiometry: 1.0
species: 740180

740180
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Glycine_C2H5NO2

762832
type: SpeciesReference
stoichiometry: 1.0
species: 742770

762882
type: SpeciesReference
stoichiometry: 1.0
species: 740168

740168
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Glycine_C2H5NO2

762675
type: SpeciesReference
stoichiometry: 1.0
species: 741765

762894
type: SpeciesReference
stoichiometry: 1.0
species: 735216

762857
type: SpeciesReference
stoichiometry: 1.0
species: 732260

732260
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Arginine_C6H15N4O2

762808
type: SpeciesReference
stoichiometry: 1.0
species: 753762

762944
type: SpeciesReference
stoichiometry: 1.0
species: 744784

762907
type: SpeciesReference
stoichiometry: 1.0
species: 751082

762772
type: SpeciesReference
stoichiometry: 1.0
species: 732344

762919
type: SpeciesReference
stoichiometry: 1.0
species: 753072

763004
type: SpeciesReference
stoichiometry: 1.0
species: 739926

763016
type: SpeciesReference
stoichiometry: 1.0
species: 749031

762980
type: SpeciesReference
stoichiometry: 1.0
species: 731549

762956
type: SpeciesReference
stoichiometry: 1.0
species: 752483

762723
type: SpeciesReference
stoichiometry: 1.0
species: 753084

762968
type: SpeciesReference
stoichiometry: 1.0
species: 753750

762627
type: SpeciesReference
stoichiometry: 1.0
species: 732272

762820
type: SpeciesReference
stoichiometry: 17.0
species: 746930

762796
type: SpeciesReference
stoichiometry: 1.0
species: 749043

762663
type: SpeciesReference
stoichiometry: 1.0
species: 752842

762747
type: SpeciesReference
stoichiometry: 1.0
species: 735228

763053
type: SpeciesReference
stoichiometry: 17.0
species: 746918

762699
type: SpeciesReference
stoichiometry: 1.0
species: 739939

762760
type: SpeciesReference
stoichiometry: 1.0
species: 751094

763041
type: SpeciesReference
stoichiometry: 1.0
species: 741753

763028
type: SpeciesReference
stoichiometry: 1.0
species: 752829

737350
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Deoxyuridine_C9H12N2O5

737278
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: dUDP_C9H11N2O11P2

738630
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Ley glycolipid_C56H99N2O30FULLRCO

737690
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Estradiol_C18H24O2

W3 CDTF: Fri Feb 03 12:51:56 GMT 2012

728149
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: trans-4-Hydroxy-L-proline_C5H9NO3

728462
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5alpha-Dihydrotestosterone glucuronide_C25H38O8

038694
type: Reaction
notes: R_URCN subsystem: Histidine Metabolism R_URCN equation: [c] : h2o + urcan --> 4izp
product: 831017
is: ENSCAFG00000003843.2
reactant: 830993
name: urocanase
fast: false
is: http://identifiers.org/ec-code/4.2.1.49
reactant: 831005
reversible: false

831017
type: SpeciesReference
stoichiometry: 1.0
species: 728173

830993
type: SpeciesReference
stoichiometry: 1.0
species: 753531

831005
type: SpeciesReference
stoichiometry: 1.0
species: 741151

743926
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 30_C219H350N15O184S9X

034288
type: Reaction
product: 788601
product: 788625
reactant: 788541
reactant: 788505
reactant: 788517
reactant: 788493
product: 788613
product: 788565
product: 788637
reactant: 788469
reactant: 788481
product: 788577
notes: R_CHOLtu subsystem: Transport, Extracellular R_CHOLtu equation: chol[e] <==> chol[c] R_PROSTGF2t subsystem: Transport, Extracellular R_PROSTGF2t equation: prostgf2[e] <==> prostgf2[c] R_NRPPHRtu subsystem: Transport, Extracellular R_NRPPHRtu equation: nrpphr[e] <==> nrpphr[c] R_DEBRISOQUINEt subsystem: Transport, Extracellular R_DEBRISOQUINEt equation: debrisoquine[e] <==> debrisoquine[c] R_SRTNtu subsystem: Transport, Extracellular R_SRTNtu equation: srtn[e] <==> srtn[c] R_PROSTGE2t2 subsystem: Transport, Extracellular R_PROSTGE2t2 equation: prostge2[e] <==> prostge2[c] R_DOPAtu subsystem: Transport, Extracellular R_DOPAtu equation: dopa[e] <==> dopa[c] R_HISTAtu subsystem: Transport, Extracellular R_HISTAtu equation: hista[e] <==> hista[c]
product: 788589
product: 788649
reactant: 788529
is: ENSCAFG00000000757.2
fast: false
reactant: 788553
reversible: true

788601
type: SpeciesReference
stoichiometry: 1.0
species: 733335

788625
type: SpeciesReference
stoichiometry: 1.0
species: 751446

788541
type: SpeciesReference
stoichiometry: 1.0
species: 733347

788505
type: SpeciesReference
stoichiometry: 1.0
species: 741790

788517
type: SpeciesReference
stoichiometry: 1.0
species: 750020

788493
type: SpeciesReference
stoichiometry: 1.0
species: 751458

788613
type: SpeciesReference
stoichiometry: 1.0
species: 750044

788565
type: SpeciesReference
stoichiometry: 1.0
species: 747553

788637
type: SpeciesReference
stoichiometry: 1.0
species: 741777

788469
type: SpeciesReference
stoichiometry: 1.0
species: 736995

788481
type: SpeciesReference
stoichiometry: 1.0
species: 735877

735877
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: debrisoquine_C10H14N3

788577
type: SpeciesReference
stoichiometry: 1.0
species: 750008

788589
type: SpeciesReference
stoichiometry: 1.0
species: 735865

788649
type: SpeciesReference
stoichiometry: 1.0
species: 736983

788529
type: SpeciesReference
stoichiometry: 1.0
species: 747565

788553
type: SpeciesReference
stoichiometry: 1.0
species: 750056

032414
type: Reaction
product: 772895
reactant: 772883
notes: R_ACGAMPM subsystem: Aminosugar Metabolism R_ACGAMPM equation: [c] : acgam6p <==> acgam1p
is: ENSCAFG00000002929.2
is: http://identifiers.org/ec-code/5.4.2.3
fast: false
reversible: true
name: phosphoacetylglucosamine mutase

772895
type: SpeciesReference
stoichiometry: 1.0
species: 730379

730379
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Acetyl-D-glucosamine 1-phosphate_C8H14NO9P

772883
type: SpeciesReference
stoichiometry: 1.0
species: 730391

730391
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Acetyl-D-glucosamine 6-phosphate_C8H14NO9P

736231
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dihydroceramide (homo sapiens)_C18H38NO2FULLRCO

040272
type: Reaction
product: 845343
reactant: 845331
notes: R_RPI subsystem: Pentose Phosphate Pathway R_RPI equation: [c] : r5p <==> ru5p-D
is: ENSCAFG00000007374.2
is: http://identifiers.org/ec-code/5.3.1.6
fast: false
reversible: true
name: ribose-5-phosphate isomerase

845343
type: SpeciesReference
stoichiometry: 1.0
species: 750695

845331
type: SpeciesReference
stoichiometry: 1.0
species: 750490

732513
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Crotonoyl-CoA_C25H36N7O17P3S

036434
type: Reaction
is: ENSCAFG00000009546.1
notes: R_GLCt4 subsystem: Transport, Extracellular R_GLCt4 equation: glc-D[e] + na1[e] <==> glc-D[c] + na1[c] R_INSTt4 subsystem: Transport, Extracellular R_INSTt4 equation: inost[e] + na1[e] <==> inost[c] + na1[c] R_NAt subsystem: Transport, Extracellular R_NAt equation: na1[e] <==> na1[c]
product: 809072
is: ENSCAFG00000018237.2
product: 809096
reactant: 809047
fast: false
is: ENSCAFG00000013498.2
reversible: true
product: 809084
reactant: 809034
reactant: 809060

809072
type: SpeciesReference
stoichiometry: 3.0
species: 746918

809096
type: SpeciesReference
stoichiometry: 1.0
species: 739815

809047
type: SpeciesReference
stoichiometry: 1.0
species: 739827

809084
type: SpeciesReference
stoichiometry: 1.0
species: 742892

809034
type: SpeciesReference
stoichiometry: 3.0
species: 746930

809060
type: SpeciesReference
stoichiometry: 1.0
species: 742904

742904
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: myo-Inositol_C6H12O6

742928
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Inosine_C10H12N4O5

734333
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Ceramide 1-phosphate_C18H35NO5PFULLRCO

031765
type: Reaction
product: 766654
product: 766678
reactant: 766618
product: 766690
reactant: 766630
is: ENSCAFG00000005466.2
product: 766702
fast: false
reversible: false
is: http://identifiers.org/ec-code/3.7.1.3
reactant: 766642
notes: R_HKYNH subsystem: Tryptophan metabolism R_HKYNH equation: [c] : h2o + hLkynr --> 3hanthrn + ala-L R_LFORKYNHYD subsystem: Tryptophan metabolism R_LFORKYNHYD equation: [c] : Lfmkynr + h2o --> ala-L + h + nformanth R_KYN subsystem: Tryptophan metabolism R_KYN equation: [c] : Lkynr + h2o --> ala-L + anth + h
product: 766666
reactant: 766606

766654
type: SpeciesReference
stoichiometry: 1.0
species: 747282

766678
type: SpeciesReference
stoichiometry: 1.0
species: 727360

766618
type: SpeciesReference
stoichiometry: 1.0
species: 729355

766690
type: SpeciesReference
stoichiometry: 3.0
species: 731549

766630
type: SpeciesReference
stoichiometry: 1.0
species: 729368

729368
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Kynurenine_C10H12N2O3

766702
type: SpeciesReference
stoichiometry: 2.0
species: 741259

766642
type: SpeciesReference
stoichiometry: 3.0
species: 741151

766666
type: SpeciesReference
stoichiometry: 1.0
species: 731912

731912
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Anthranilate_C7H6NO2

766606
type: SpeciesReference
stoichiometry: 1.0
species: 741247

038124
type: Reaction
reactant: 826651
is: http://identifiers.org/ec-code/3.2.1.49
product: 826687
reversible: false
product: 826712
reactant: 826663
product: 826699
reactant: 826675
fast: false
notes: R_NAGAly subsystem: Sphingolipid Metabolism R_NAGAly equation: [l] : acgagbside_hs + h + udp --> gbside_hs + udpacgal R_NAGA2ly subsystem: Keratan sulfate degradation R_NAGA2ly equation: [l] : Tn_antigen + h + udp --> Ser/Thr + udpacgal
is: ENSCAFG00000019874.2
reactant: 826639

826651
type: SpeciesReference
stoichiometry: 1.0
species: 730283

730283
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: alpha GalNAc globoside (homo sapiens)_C52H92N3O27FULLRCO

826687
type: SpeciesReference
stoichiometry: 1.0
species: 729798

729798
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: protein-linked serine or threonine residue (O-glycosylation site)_XH

826712
type: SpeciesReference
stoichiometry: 1.0
species: 739474

739474
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: globoside (homo sapiens)_C44H79N2O22FULLRCO

826663
type: SpeciesReference
stoichiometry: 1.0
species: 729871

729871
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Tn antigen_C8H14NO5X

826699
type: SpeciesReference
stoichiometry: 2.0
species: 753242

753242
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101

826675
type: SpeciesReference
stoichiometry: 2.0
species: 753169

753169
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: UDP_C9H11N2O12P2

826639
type: SpeciesReference
stoichiometry: 2.0
species: 741296

038294
type: Reaction
is: ENSCAFG00000002994.2
is: http://identifiers.org/ec-code/3.1.3.5
product: 827990
notes: R_NTD7e subsystem: Nucleotides R_NTD7e equation: [e] : amp + h2o --> adn + pi R_NTD2e subsystem: Nucleotides R_NTD2e equation: [e] : h2o + ump --> pi + uri R_NTD9e subsystem: Nucleotides R_NTD9e equation: [e] : gmp + h2o --> gsn + pi R_NTD4e subsystem: Nucleotides R_NTD4e equation: [e] : cmp + h2o --> cytd + pi
fast: false
reactant: 827930
reactant: 827906
reactant: 827882
product: 827978
product: 827942
reactant: 827918
reversible: false
reactant: 827894
product: 827966
product: 827954

827990
type: SpeciesReference
stoichiometry: 1.0
species: 740762

740762
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Guanosine_C10H13N5O5

827930
type: SpeciesReference
stoichiometry: 1.0
species: 753411

753411
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: UMP_C9H11N2O9P

827906
type: SpeciesReference
stoichiometry: 1.0
species: 731767

827882
type: SpeciesReference
stoichiometry: 1.0
species: 740542

740542
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: GMP_C10H12N5O8P

827978
type: SpeciesReference
stoichiometry: 1.0
species: 730874

730874
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Adenosine_C10H13N5O4

827942
type: SpeciesReference
stoichiometry: 1.0
species: 753591

753591
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Uridine_C9H12N2O6

827918
type: SpeciesReference
stoichiometry: 4.0
species: 741163

827894
type: SpeciesReference
stoichiometry: 1.0
species: 733871

733871
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: CMP_C9H12N3O8P

827966
type: SpeciesReference
stoichiometry: 1.0
species: 735288

827954
type: SpeciesReference
stoichiometry: 4.0
species: 749213

749007
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: phosphatidylglycerol (homo sapiens)_C6H12O6PFULLRCO2FULLR2CO2

744265
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 3_C47H76N4O33X

041166
type: Reaction
reversible: false
product: 855231
notes: R_RBK subsystem: Pentose Phosphate Pathway R_RBK equation: [c] : atp + rib-D --> adp + h + r5p R_DRBK subsystem: Pentose Phosphate Pathway R_DRBK equation: [c] : atp + drib --> 2dr5p + adp + h
reactant: 855206
reactant: 855182
product: 855255
is: http://identifiers.org/ec-code/2.7.1.15
reactant: 855194
is: ENSCAFG00000005191.2
fast: false
product: 855219
product: 855243

855231
type: SpeciesReference
stoichiometry: 2.0
species: 730922

855206
type: SpeciesReference
stoichiometry: 1.0
species: 737055

855182
type: SpeciesReference
stoichiometry: 1.0
species: 750659

750659
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Ribose_C5H10O5

855255
type: SpeciesReference
stoichiometry: 2.0
species: 741259

855194
type: SpeciesReference
stoichiometry: 2.0
species: 732441

855219
type: SpeciesReference
stoichiometry: 1.0
species: 750490

855243
type: SpeciesReference
stoichiometry: 1.0
species: 726900

753096
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Tyrosine_C9H11NO3

031729
type: Reaction
reactant: 765620
product: 765644
name: choline dehydrogenase (FAD acceptor), mitochondrial
is: http://identifiers.org/ec-code/1.1.99.1
product: 765632
notes: R_CHOLD2m subsystem: Glycine, Serine, and Threonine Metabolism R_CHOLD2m equation: [m] : chol + fad --> betald + fadh2
fast: false
reversible: false
is: ENSCAFG00000008296.2
reactant: 765608

765620
type: SpeciesReference
stoichiometry: 1.0
species: 733371

733371
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Choline_C5H14NO

765644
type: SpeciesReference
stoichiometry: 1.0
species: 738087

765632
type: SpeciesReference
stoichiometry: 1.0
species: 732587

732587
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Betaine aldehyde_C5H12NO

765608
type: SpeciesReference
stoichiometry: 1.0
species: 738039

745158
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: linoleic coenzyme A_C39H62N7O17P3S

738738
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Type IIIH glycolipid_C70H122N3O40FULLRCO

747014
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

036034
type: Reaction
reactant: 806027
name: L-asparaginase (mitochondrial)
product: 806039
is: http://identifiers.org/ec-code/3.5.1.1
product: 806051
notes: R_ASNNm subsystem: Alanine and Aspartate Metabolism R_ASNNm equation: [m] : asn-L + h2o --> asp-L + nh4
is: ENSCAFG00000015868.2
fast: false
reactant: 806015
reversible: false

806027
type: SpeciesReference
stoichiometry: 1.0
species: 732356

732356
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Asparagine_C4H8N2O3

806039
type: SpeciesReference
stoichiometry: 1.0
species: 747319

806051
type: SpeciesReference
stoichiometry: 1.0
species: 732429

732429
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Aspartate_C4H6NO4

806015
type: SpeciesReference
stoichiometry: 1.0
species: 741199

735673
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: docosa-4,7,10,13,16-pentaenoyl coenzyme A_C43H64N7O17P3S

031174
type: Reaction
is: ENSCAFG00000016098.2
fast: false
is: ENSCAFG00000003774.2
is: http://identifiers.org/ec-code/4.2.1.11
name: enolase
is: ENSCAFG00000019697.2
product: 761017
product: 761029
reactant: 761005
reversible: true
notes: R_ENO subsystem: Glycolysis/Gluconeogenesis R_ENO equation: [c] : 2pg <==> h2o + pep
is: ENSCAFG00000015802.2

761017
type: SpeciesReference
stoichiometry: 1.0
species: 741151

761029
type: SpeciesReference
stoichiometry: 1.0
species: 748910

761005
type: SpeciesReference
stoichiometry: 1.0
species: 727045

727045
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Glycerate 2-phosphate_C3H4O7P

750866
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Sarcosine_C3H7NO2

744350
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 4-linked), degradation product 1_C78H126N6O64S3X

753181
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: UDP_C9H11N2O12P2

037363
type: Reaction
product: 817547
is: http://identifiers.org/ec-code/2.4.1.148
reactant: 817523
is: http://identifiers.org/ec-code/2.4.1.102
is: ENSCAFG00000016661.1
product: 817559
reactant: 817511
notes: R_CORE2GTg subsystem: O-Glycan Biosynthesis R_CORE2GTg equation: [g] : T_antigen + uacgam --> core2 + h + udp R_CORE4GTg subsystem: O-Glycan Biosynthesis R_CORE4GTg equation: [g] : core3 + uacgam --> core4 + h + udp
product: 817571
fast: false
product: 817535
reversible: false
reactant: 817499

817547
type: SpeciesReference
stoichiometry: 2.0
species: 753157

817523
type: SpeciesReference
stoichiometry: 1.0
species: 729846

817559
type: SpeciesReference
stoichiometry: 2.0
species: 741283

817511
type: SpeciesReference
stoichiometry: 1.0
species: 734163

817571
type: SpeciesReference
stoichiometry: 1.0
species: 734151

817535
type: SpeciesReference
stoichiometry: 1.0
species: 734175

734175
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Core 4_C24H40N3O15X

817499
type: SpeciesReference
stoichiometry: 2.0
species: 753121

727929
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4,6-Dihydroxyquinoline_C9H7NO2

744484
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 5_C69H112N6O48X

742031
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 13_C55H83N3O61S5

733153
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Carbamoyl phosphate_CH2NO5P

735529
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Decanoyl-CoA (n-C10:0CoA)_C31H50N7O17P3S

729404
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Acetylserotonin_C12H14N2O2

727480
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Hydroxypropanoate_C3H5O3

034529
type: Reaction
product: 790823
notes: R_ACOAD8m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ACOAD8m equation: [m] : fad + ivcoa --> 3mb2coa + fadh2
reactant: 790798
is: ENSCAFG00000023724.1
is: ENSCAFG00000003954.2
name: acyl-CoA dehydrogenase (isovaleryl-CoA), mitochondrial
reversible: false
fast: false
is: ENSCAFG00000000578.2
reactant: 790811
product: 790835
is: http://identifiers.org/ec-code/1.3.99.10

790823
type: SpeciesReference
stoichiometry: 1.0
species: 727552

727552
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3-Methylbut-2-enoyl-CoA_C26H38N7O17P3S

790798
type: SpeciesReference
stoichiometry: 1.0
species: 743060

743060
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Isovaleryl-CoA_C26H40N7O17P3S

790811
type: SpeciesReference
stoichiometry: 1.0
species: 738039

790835
type: SpeciesReference
stoichiometry: 1.0
species: 738087

036869
type: Reaction
product: 812300
is: ENSCAFG00000016423.2
is: http://identifiers.org/ec-code/2.4.1.198
reversible: false
is: ENSCAFG00000009702.2
reactant: 812251
is: ENSCAFG00000014703.2
name: phosphatidylinositol N-acetylglucosaminyltransferase
product: 812275
is: ENSCAFG00000019662.2
reactant: 812263
product: 812288
fast: false
is: ENSCAFG00000011932.2
notes: R_PIACGT subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_PIACGT equation: [c] : pail_hs + uacgam --> acgpail_hs + h + udp

812300
type: SpeciesReference
stoichiometry: 1.0
species: 741259

812251
type: SpeciesReference
stoichiometry: 1.0
species: 748591

812275
type: SpeciesReference
stoichiometry: 1.0
species: 753133

753133
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: UDP_C9H11N2O12P2

812263
type: SpeciesReference
stoichiometry: 1.0
species: 753109

812288
type: SpeciesReference
stoichiometry: 1.0
species: 730524

732032
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Acetylputrescine_C6H15N2O

736559
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: dITP_C10H11N4O13P3

040513
type: Reaction
reactant: 847594
product: 847618
notes: R_HCO3_NAt subsystem: Transport, Extracellular R_HCO3_NAt equation: hco3[e] + na1[e] <==> hco3[c] + na1[c]
product: 847630
is: ENSCAFG00000024704.1
fast: false
reactant: 847606
reversible: true
is: ENSCAFG00000005613.2
name: bicarbonate transport (Na/HCO3 cotransport)

847594
type: SpeciesReference
stoichiometry: 1.0
species: 746930

847618
type: SpeciesReference
stoichiometry: 1.0
species: 741416

847630
type: SpeciesReference
stoichiometry: 1.0
species: 746918

847606
type: SpeciesReference
stoichiometry: 1.0
species: 741428

032883
type: Reaction
reactant: 776915
is: ENSCAFG00000019901.2
reversible: false
notes: R_METLEUex subsystem: Transport, Extracellular R_METLEUex equation: leu-L[c] + met-L[e] --> leu-L[e] + met-L[c]
fast: false
product: 776939
product: 776927
reactant: 776903
name: Methionine/Leucine exchange (Met in)

776915
type: SpeciesReference
stoichiometry: 1.0
species: 744784

776939
type: SpeciesReference
stoichiometry: 1.0
species: 746291

776927
type: SpeciesReference
stoichiometry: 1.0
species: 744796

776903
type: SpeciesReference
stoichiometry: 1.0
species: 746303

036143
type: Reaction
reversible: false
notes: R_SPODMe subsystem: ROS Detoxification R_SPODMe equation: [e] : (2) h + (2) o2s --> h2o2 + o2
reactant: 806905
is: http://identifiers.org/ec-code/1.15.1.1
name: superoxide dismutase, extracellular
product: 806929
fast: false
product: 806941
is: ENSCAFG00000016498.2
reactant: 806917

806905
type: SpeciesReference
stoichiometry: 2.0
species: 741271

806929
type: SpeciesReference
stoichiometry: 1.0
species: 747710

747710
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: O2_O2

806941
type: SpeciesReference
stoichiometry: 1.0
species: 741090

741090
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Hydrogen peroxide_H2O2

806917
type: SpeciesReference
stoichiometry: 2.0
species: 747782

747782
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Superoxide anion_O2

038912
type: Reaction
reactant: 832544
notes: R_CGLYt3_LPAREN_2_RPAREN_ subsystem: Transport, Extracellular R_CGLYt3_LPAREN_2_RPAREN_ equation: cgly[e] + (2) h[e] --> cgly[c] + (2) h[c]
reversible: false
reactant: 832532
name: Cys-Gly transport in via proton symport
fast: false
product: 832568
is: ENSCAFG00000011672.2
product: 832556

832544
type: SpeciesReference
stoichiometry: 1.0
species: 733286

733286
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Cys-Gly_C5H10N2O3S

832532
type: SpeciesReference
stoichiometry: 2.0
species: 741271

832568
type: SpeciesReference
stoichiometry: 2.0
species: 741259

832556
type: SpeciesReference
stoichiometry: 1.0
species: 733274

733274
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Cys-Gly_C5H10N2O3S

033233
type: Reaction
reversible: false
is: ENSCAFG00000001056.2
notes: R_SQLEr subsystem: Cholesterol Metabolism R_SQLEr equation: [r] : h + nadph + o2 + sql --> Ssq23epx + h2o + nadp
reactant: 779303
fast: false
product: 779339
product: 779327
reactant: 779267
reactant: 779291
name: Squalene epoxidase, endoplasmic reticular (NADP)
product: 779315
is: http://identifiers.org/ec-code/1.14.99.7
reactant: 779279

779303
type: SpeciesReference
stoichiometry: 1.0
species: 741332

779339
type: SpeciesReference
stoichiometry: 1.0
species: 747148

779327
type: SpeciesReference
stoichiometry: 1.0
species: 741223

779267
type: SpeciesReference
stoichiometry: 1.0
species: 747746

779291
type: SpeciesReference
stoichiometry: 1.0
species: 747209

779315
type: SpeciesReference
stoichiometry: 1.0
species: 729822

779279
type: SpeciesReference
stoichiometry: 1.0
species: 751434

748387
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens)_C11H23O4NPFULLRCO2

742624
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Isocitrate_C6H5O7

732768
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Biocytin_C16H28N4O4S

744314
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 7_C67H108N5O51SX

746315
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5,10-Methenyltetrahydrofolate_C20H20N7O6

738135
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Formaldehyde_CH2O

726331
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _10-Formyltetrahydrofolate_C20H21N7O7

729066
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: hexaglutamyl folate (THF)_C44H51N12O21

735204
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Hydrogen cyanide_CHN

746449
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1D-myo-Inositol 1,3,4-trisphosphate_C6H9O15P3

737115
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: dTDP_C10H13N2O11P2

731224
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _3alpha-Hydroxy-5beta-androstan-17-one_C19H30O2

740970
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: GTP_C10H12N5O14P3

746400
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: _1D-myo-Inositol 1,3,4,5,6-pentakisphosphate_C6H7O21P5

751046
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Selenophosphate_H2O3PSe

751214
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Sulfate_O4S

032210
type: Reaction
reactant: 770777
product: 770950
reactant: 770803
fast: false
is: ENSCAFG00000024037.1
reactant: 770913
reactant: 770938
reactant: 770790
reactant: 770827
reactant: 770876
product: 771010
reactant: 770839
product: 770974
reactant: 770901
reactant: 770851
notes: R_DALAt2r subsystem: Transport, Extracellular R_DALAt2r equation: ala-D[e] + h[e] <==> ala-D[c] + h[c] R_ALAt2rL subsystem: Transport, Lysosomal R_ALAt2rL equation: ala-L[l] + h[l] <==> ala-L[c] + h[c] R_DALAt2rL subsystem: Transport, Lysosomal R_DALAt2rL equation: ala-D[l] + h[l] <==> ala-D[c] + h[c] R_ABUTt2r subsystem: Transport, Extracellular R_ABUTt2r equation: _4abut[e] + h[e] <==> 4abut[c] + h[c] R_PROt2r subsystem: Transport, Extracellular R_PROt2r equation: h[e] + pro-L[e] <==> h[c] + pro-L[c] R_ALAt2r subsystem: Transport, Extracellular R_ALAt2r equation: ala-L[e] + h[e] <==> ala-L[c] + h[c] R_GLYt2r subsystem: Transport, Extracellular R_GLYt2r equation: gly[e] + h[e] <==> gly[c] + h[c] R_PRODt2rL subsystem: Transport, Lysosomal R_PRODt2rL equation: h[l] + pro-D[l] <==> h[c] + pro-D[c] R_PROt2rL subsystem: Transport, Lysosomal R_PROt2rL equation: h[l] + pro-L[l] <==> h[c] + pro-L[c] R_PRODt2r subsystem: Transport, Extracellular R_PRODt2r equation: h[e] + pro-D[e] <==> h[c] + pro-D[c] R_ABUTt2rL subsystem: Transport, Lysosomal R_ABUTt2rL equation: _4abut[l] + h[l] <==> 4abut[c] + h[c] R_GLYt2rL subsystem: Transport, Lysosomal R_GLYt2rL equation: gly[l] + h[l] <==> gly[c] + h[c]
reactant: 770815
product: 771022
product: 770998
product: 770962
reactant: 770925
reactant: 770864
reversible: true
product: 770986
reactant: 770888

770777
type: SpeciesReference
stoichiometry: 1.0
species: 749839

749839
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: D-Proline_C5H9NO2

770950
type: SpeciesReference
stoichiometry: 2.0
species: 727979

770803
type: SpeciesReference
stoichiometry: 6.0
species: 741271

770913
type: SpeciesReference
stoichiometry: 1.0
species: 731525

731525
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: D-Alanine_C3H7NO2

770938
type: SpeciesReference
stoichiometry: 1.0
species: 749851

749851
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: D-Proline_C5H9NO2

770790
type: SpeciesReference
stoichiometry: 1.0
species: 731513

731513
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: D-Alanine_C3H7NO2

770827
type: SpeciesReference
stoichiometry: 1.0
species: 731561

770876
type: SpeciesReference
stoichiometry: 1.0
species: 740180

771010
type: SpeciesReference
stoichiometry: 2.0
species: 731501

731501
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Alanine_C3H7NO2

770839
type: SpeciesReference
stoichiometry: 6.0
species: 741296

770974
type: SpeciesReference
stoichiometry: 2.0
species: 749827

770901
type: SpeciesReference
stoichiometry: 1.0
species: 727991

727991
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _4-Aminobutanoate_C4H9NO2

770851
type: SpeciesReference
stoichiometry: 1.0
species: 749887

770815
type: SpeciesReference
stoichiometry: 1.0
species: 731573

731573
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: L-Alanine_C3H7NO2

771022
type: SpeciesReference
stoichiometry: 12.0
species: 741259

770998
type: SpeciesReference
stoichiometry: 2.0
species: 749875

770962
type: SpeciesReference
stoichiometry: 2.0
species: 740168

770925
type: SpeciesReference
stoichiometry: 1.0
species: 740193

740193
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Glycine_C2H5NO2

770864
type: SpeciesReference
stoichiometry: 1.0
species: 749899

749899
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: L-Proline_C5H9NO2

770986
type: SpeciesReference
stoichiometry: 2.0
species: 731549

770888
type: SpeciesReference
stoichiometry: 1.0
species: 728003

728003
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: _4-Aminobutanoate_C4H9NO2

038888
type: Reaction
reactant: 832280
reversible: false
is: ENSCAFG00000010466.2
reactant: 832268
reactant: 832304
product: 832352
product: 832328
product: 832340
reactant: 832292
notes: R_DOLPGT3_Ler subsystem: N-Glycan Biosynthesis R_DOLPGT3_Ler equation: [r] : (0.1) dolglcp_L + (0.1) g2m8mpdol_L --> (0.1) dolp_L + (0.1) g3m8mpdol_L + h R_DOLPGT3_Uer subsystem: N-Glycan Biosynthesis R_DOLPGT3_Uer equation: [r] : (0.1) dolglcp_U + (0.1) g2m8mpdol_U --> (0.1) dolp_U + (0.1) g3m8mpdol_U + h
fast: false
product: 832364
product: 832316

832280
type: SpeciesReference
stoichiometry: 1.0
species: 736849

736849
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dolichyl beta-D-glucosyl phosphate, human liver homolog_C1140H1868O90P10

832268
type: SpeciesReference
stoichiometry: 1.0
species: 738955

738955
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1845H3040N20O720P20

832304
type: SpeciesReference
stoichiometry: 1.0
species: 738943

738943
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1900H3128N20O720P20

832352
type: SpeciesReference
stoichiometry: 1.0
species: 738979

832328
type: SpeciesReference
stoichiometry: 1.0
species: 738991

832340
type: SpeciesReference
stoichiometry: 1.0
species: 736971

832292
type: SpeciesReference
stoichiometry: 1.0
species: 736874

736874
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dolichyl beta-D-glucosyl phosphate, human uterine homolog_C1085H1780O90P10

832364
type: SpeciesReference
stoichiometry: 2.0
species: 741332

832316
type: SpeciesReference
stoichiometry: 1.0
species: 736947

032571
type: Reaction
modifier: 774253
product: 774229
reactant: 774217
notes: R_L_DASH_LACtcm subsystem: Transport, Mitochondrial R_L_DASH_LACtcm equation: lac-L[c] --> lac-L[m] R_UREAtm subsystem: Urea cycle/amino group metabolism R_UREAtm equation: urea[c] <==> urea[m]
fast: false
is: ENSCAFG00000016556.1
modifier: 774241
reversible: false

753567
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Urea_CH4N2O

774229
type: SpeciesReference
stoichiometry: 1.0
species: 744663

774217
type: SpeciesReference
stoichiometry: 1.0
species: 744637

037447
type: Reaction
reversible: false
reactant: 818485
fast: false
is: http://identifiers.org/ec-code/2.4.1.11
product: 818533
notes: R_GLGNS1 subsystem: Starch and Sucrose Metabolism R_GLGNS1 equation: [c] : ggn + (3) udpg --> glygn1 + (3) h + (3) udp R_GGNG subsystem: Starch and Sucrose Metabolism R_GGNG equation: [c] : Tyr-ggn + (8) udpg --> ggn + (8) h + (8) udp
product: 818545
is: ENSCAFG00000008249.2
reactant: 818473
is: ENSCAFG00000011113.2
product: 818509
is: ENSCAFG00000025047.1
product: 818521
is: ENSCAFG00000003858.2
reactant: 818497

818485
type: SpeciesReference
stoichiometry: 1.0
species: 739778

739778
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: primed glycogenin (glycogenin-8[1,4-Glc])_C48H81O41X

818533
type: SpeciesReference
stoichiometry: 11.0
species: 753133

818545
type: SpeciesReference
stoichiometry: 11.0
species: 741259

818473
type: SpeciesReference
stoichiometry: 11.0
species: 753266

818509
type: SpeciesReference
stoichiometry: 1.0
species: 740385

740385
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: glycogen, structure 1 (glycogenin-11[1,4-Glc])_C66H111O56X

818521
type: SpeciesReference
stoichiometry: 1.0
species: 739778

818497
type: SpeciesReference
stoichiometry: 1.0
species: 729883

038731
type: Reaction
product: 831258
product: 831270
notes: R_SIAT9g subsystem: Sphingolipid Metabolism R_SIAT9g equation: [g] : cmpacna + galgluside_hs --> cmp + gm3_hs + h
reactant: 831234
is: http://identifiers.org/ec-code/2.4.99.9
fast: false
name: Lactosylceramide alpha-2,3-sialyltransferase, Golgi apparatus
product: 831282
is: ENSCAFG00000007653.2
reactant: 831246
reversible: false

831258
type: SpeciesReference
stoichiometry: 1.0
species: 741283

831270
type: SpeciesReference
stoichiometry: 1.0
species: 733884

831234
type: SpeciesReference
stoichiometry: 1.0
species: 733933

831282
type: SpeciesReference
stoichiometry: 1.0
species: 740518

831246
type: SpeciesReference
stoichiometry: 1.0
species: 739341

752386
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Thiamin_C12H17N4OS

033511
type: Reaction
product: 781921
notes: R_THMt3 subsystem: Transport, Extracellular R_THMt3 equation: h[c] + thm[e] <==> h[e] + thm[c]
reversible: true
product: 781909
is: ENSCAFG00000025024.1
reactant: 781897
is: ENSCAFG00000006857.2
reactant: 781885
fast: false
name: Thiamine transport in via proton antiport

781921
type: SpeciesReference
stoichiometry: 1.0
species: 752386

781909
type: SpeciesReference
stoichiometry: 1.0
species: 741271

781897
type: SpeciesReference
stoichiometry: 1.0
species: 741259

781885
type: SpeciesReference
stoichiometry: 1.0
species: 752398

753991
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al_C27H46O3

751348
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO

745495
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (alpha-D-mannosyl)2-beta-D-mannosyl-N-acetylglucosamine_C26H45NO21

727202
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _3',5'-Cyclic GMP_C10H11N5O7P

034841
type: Reaction
reactant: 793606
product: 793630
product: 793642
modifier: 793702
is: ENSCAFG00000018253.2
modifier: 793690
reactant: 793618
is: http://identifiers.org/ec-code/2.1.2.1
modifier: 793678
modifier: 793654
fast: false
modifier: 793666
reversible: false
notes: R_GHMT3 subsystem: Lysine Metabolism R_GHMT3 equation: [c] : 3htmelys + h --> 4tmeabut + gly R_GHMT2r subsystem: Glycine, Serine, and Threonine Metabolism R_GHMT2r equation: [c] : ser-L + thf <==> gly + h2o + mlthf

793606
type: SpeciesReference
stoichiometry: 1.0
species: 727492

793630
type: SpeciesReference
stoichiometry: 1.0
species: 740168

793642
type: SpeciesReference
stoichiometry: 1.0
species: 728342

728342
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Trimethylammoniobutanal_C7H16NO

793618
type: SpeciesReference
stoichiometry: 1.0
species: 741259

738534
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Lea glycolipid_C50H89N2O26FULLRCO

036519
type: Reaction
is: ENSCAFG00000016019.2
reactant: 809701
product: 809749
product: 809713
reactant: 809676
reversible: false
product: 809725
reactant: 809651
is: http://identifiers.org/ec-code/1.14.19.1
notes: R_DESAT20_1 subsystem: Fatty acid elongation R_DESAT20_1 equation: [c] : dlnlcgcoa + h + nadh + o2 --> arachdcoa + (2) h2o + nad R_DESAT20_2 subsystem: Fatty acid elongation R_DESAT20_2 equation: [c] : eicostetcoa + h + nadh + o2 --> (2) h2o + nad + tmndnccoa
reactant: 809664
is: ENSCAFG00000025083.1
fast: false
product: 809737
reactant: 809688

809701
type: SpeciesReference
stoichiometry: 2.0
species: 747050

809749
type: SpeciesReference
stoichiometry: 4.0
species: 741151

809713
type: SpeciesReference
stoichiometry: 1.0
species: 732188

809676
type: SpeciesReference
stoichiometry: 2.0
species: 747698

809725
type: SpeciesReference
stoichiometry: 2.0
species: 746978

809651
type: SpeciesReference
stoichiometry: 1.0
species: 736583

809664
type: SpeciesReference
stoichiometry: 1.0
species: 737533

809737
type: SpeciesReference
stoichiometry: 1.0
species: 752642

809688
type: SpeciesReference
stoichiometry: 2.0
species: 741259

032967
type: Reaction
reactant: 777555
is: ENSCAFG00000025347.1
reactant: 777543
fast: false
name: protein lysine peptidase (endoplasmic reticulum)
is: ENSCAFG00000008927.2
notes: R_PLYSPSer subsystem: Lysine Metabolism R_PLYSPSer equation: [r] : Ntmelys + h2o --> pepslys + tmlys
product: 777567
reversible: false
is: ENSCAFG00000005457.2
is: ENSCAFG00000000100.2
product: 777579
is: ENSCAFG00000012889.2

777555
type: SpeciesReference
stoichiometry: 1.0
species: 741223

777543
type: SpeciesReference
stoichiometry: 1.0
species: 729453

729453
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Protein N6,N6,N6-trimethyl-L-lysine_C3H10X

777567
type: SpeciesReference
stoichiometry: 1.0
species: 748947

748947
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: peptide sans lysine_X

777579
type: SpeciesReference
stoichiometry: 1.0
species: 752617

752617
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: N6,N6,N6-Trimethyl-L-lysine_C9H20N2O2

753507
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Uracil_C4H4N2O2

729138
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heptaglutamyl folate (DHF)_C49H55N13O24

039092
type: Reaction
product: 834349
product: 834325
is: http://identifiers.org/ec-code/1.2.1.21
product: 834253
notes: R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD20x subsystem: Tryptophan metabolism R_ALDD20x equation: [c] : h2o + id3acald + nad --> (2) h + ind3ac + nadh R_BAMPPALDOX subsystem: beta-Alanine metabolism R_BAMPPALDOX equation: [c] : bamppald + h2o + nad --> ala-B + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_IMACTD subsystem: Histidine Metabolism R_IMACTD equation: [c] : h2o + im4act + nad --> (2) h + im4ac + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_PYLALDOX subsystem: Limonene and pinene degradation R_PYLALDOX equation: [c] : h2o + nad + pylald --> (2) h + nadh + peracd R_NABTNO subsystem: Arginine and Proline Metabolism R_NABTNO equation: [c] : h2o + n4abutn + nad --> 4aabutn + (2) h + nadh R_5HOXINDACTOX subsystem: Tryptophan metabolism R_5HOXINDACTOX equation: [c] : 5hoxindact + h2o + nad --> 5hoxindoa + (2) h + nadh R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh
product: 834337
reactant: 834132
product: 834313
product: 834241
reversible: false
reactant: 834084
product: 834301
product: 834361
fast: false
product: 834289
reactant: 834096
reactant: 834192
reactant: 834204
reactant: 834168
product: 834373
reactant: 834108
is: http://identifiers.org/ec-code/1.2.1.3
product: 834229
reactant: 834072
reactant: 834144
product: 834277
reactant: 834180
reactant: 834156
product: 834265
is: ENSCAFG00000001791.2
reactant: 834216
reactant: 834120

834349
type: SpeciesReference
stoichiometry: 1.0
species: 744598

834325
type: SpeciesReference
stoichiometry: 1.0
species: 748959

834253
type: SpeciesReference
stoichiometry: 1.0
species: 742868

834337
type: SpeciesReference
stoichiometry: 1.0
species: 731465

834132
type: SpeciesReference
stoichiometry: 1.0
species: 739486

834313
type: SpeciesReference
stoichiometry: 1.0
species: 744637

834241
type: SpeciesReference
stoichiometry: 1.0
species: 740349

834084
type: SpeciesReference
stoichiometry: 1.0
species: 746882

834301
type: SpeciesReference
stoichiometry: 1.0
species: 728692

834361
type: SpeciesReference
stoichiometry: 23.0
species: 741259

834289
type: SpeciesReference
stoichiometry: 1.0
species: 739877

834096
type: SpeciesReference
stoichiometry: 1.0
species: 742819

834192
type: SpeciesReference
stoichiometry: 12.0
species: 741151

834204
type: SpeciesReference
stoichiometry: 1.0
species: 739790

834168
type: SpeciesReference
stoichiometry: 1.0
species: 728668

834373
type: SpeciesReference
stoichiometry: 11.0
species: 747050

834108
type: SpeciesReference
stoichiometry: 1.0
species: 750345

834229
type: SpeciesReference
stoichiometry: 1.0
species: 742794

834072
type: SpeciesReference
stoichiometry: 1.0
species: 744700

834144
type: SpeciesReference
stoichiometry: 1.0
species: 730076

834277
type: SpeciesReference
stoichiometry: 1.0
species: 727955

834180
type: SpeciesReference
stoichiometry: 1.0
species: 742660

834156
type: SpeciesReference
stoichiometry: 1.0
species: 732537

834265
type: SpeciesReference
stoichiometry: 1.0
species: 729979

834216
type: SpeciesReference
stoichiometry: 1.0
species: 744676

834120
type: SpeciesReference
stoichiometry: 11.0
species: 746978

742940
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Inosine_C10H12N4O5

747490
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Methylputrescine_C5H16N2

749984
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Prostaglandin E1_C20H33O5

740337
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Glycerol_C3H8O3

734634
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate B (IdoA2S-GalNAc4S), precursor 4_C45H67N2O42S2X

736340
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _7,8-Dihydrofolate_C19H19N7O6

031861
type: Reaction
product: 767376
product: 767327
reactant: 767291
notes: R_HEX10 subsystem: Aminosugar Metabolism R_HEX10 equation: [c] : atp + gam --> adp + gam6p + h R_HEX4 subsystem: Fructose and Mannose Metabolism R_HEX4 equation: [c] : atp + man --> adp + h + man6p R_HEX7 subsystem: Fructose and Mannose Metabolism R_HEX7 equation: [c] : atp + fru --> adp + f6p + h R_HEX1 subsystem: Glycolysis/Gluconeogenesis R_HEX1 equation: [c] : atp + glc-D --> adp + g6p + h
product: 767364
product: 767351
is: ENSCAFG00000002944.2
reactant: 767315
product: 767388
reactant: 767267
is: ENSCAFG00000008265.2
reactant: 767279
is: http://identifiers.org/ec-code/2.7.1.7
is: http://identifiers.org/ec-code/2.7.1.1
reactant: 767303
is: ENSCAFG00000016584.2
fast: false
reversible: false
is: ENSCAFG00000013917.2
product: 767339

767376
type: SpeciesReference
stoichiometry: 1.0
species: 746049

746049
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Mannose 6-phosphate_C6H11O9P

767327
type: SpeciesReference
stoichiometry: 1.0
species: 739414

739414
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Glucosamine 6-phosphate_C6H13NO8P

767291
type: SpeciesReference
stoichiometry: 1.0
species: 738474

767364
type: SpeciesReference
stoichiometry: 1.0
species: 738015

767351
type: SpeciesReference
stoichiometry: 4.0
species: 730922

767315
type: SpeciesReference
stoichiometry: 1.0
species: 739815

767388
type: SpeciesReference
stoichiometry: 4.0
species: 741259

767267
type: SpeciesReference
stoichiometry: 4.0
species: 732441

767279
type: SpeciesReference
stoichiometry: 1.0
species: 746061

767303
type: SpeciesReference
stoichiometry: 1.0
species: 739426

767339
type: SpeciesReference
stoichiometry: 1.0
species: 739027

038598
type: Reaction
reactant: 830241
product: 830337
product: 830265
is: http://identifiers.org/ec-code/3.1.6.12
is: ENSCAFG00000009168.2
reversible: true
product: 830277
reactant: 830217
product: 830289
product: 830301
reactant: 830253
reactant: 830205
notes: R_S4TASE2ly subsystem: Chondroitin sulfate degradation R_S4TASE2ly equation: [l] : cs_a_deg3 + h2o <==> cs_a_deg4 + h + so4 R_S4TASE3ly subsystem: Chondroitin sulfate degradation R_S4TASE3ly equation: [l] : cs_b + h2o <==> cs_b_deg1 + h + so4 R_S4TASE1ly subsystem: Chondroitin sulfate degradation R_S4TASE1ly equation: [l] : cs_a + h2o <==> cs_a_deg1 + h + so4 R_S4TASE5ly subsystem: Chondroitin sulfate degradation R_S4TASE5ly equation: [l] : cs_e_deg4 + h2o <==> cs_e_deg5 + h + so4 R_S4TASE4ly subsystem: Chondroitin sulfate degradation R_S4TASE4ly equation: [l] : cs_e + h2o <==> cs_e_deg1 + h + so4
product: 830313
fast: false
product: 830325
reactant: 830229
reactant: 830193

830241
type: SpeciesReference
stoichiometry: 1.0
species: 734537

734537
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 3_C31H48NO32S2

830337
type: SpeciesReference
stoichiometry: 1.0
species: 734513

830265
type: SpeciesReference
stoichiometry: 1.0
species: 734549

830277
type: SpeciesReference
stoichiometry: 1.0
species: 734585

830217
type: SpeciesReference
stoichiometry: 1.0
species: 734622

830289
type: SpeciesReference
stoichiometry: 5.0
species: 751227

830301
type: SpeciesReference
stoichiometry: 5.0
species: 741296

830253
type: SpeciesReference
stoichiometry: 1.0
species: 734987

830205
type: SpeciesReference
stoichiometry: 1.0
species: 734939

830313
type: SpeciesReference
stoichiometry: 1.0
species: 734951

734951
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 5_C31H47NO35S3

830325
type: SpeciesReference
stoichiometry: 1.0
species: 734902

830229
type: SpeciesReference
stoichiometry: 5.0
species: 741187

830193
type: SpeciesReference
stoichiometry: 1.0
species: 734573

033378
type: Reaction
reactant: 780952
is: http://identifiers.org/ec-code/1.5.1.20
reactant: 780940
product: 780976
fast: false
is: ENSCAFG00000016558.2
name: _5,10-methylenetetrahydrofolatereductase (NADPH)
product: 780964
reversible: false
notes: R_MTHFR3 subsystem: Folate Metabolism R_MTHFR3 equation: [c] : (2) h + mlthf + nadph --> 5mthf + nadp
reactant: 780928

780952
type: SpeciesReference
stoichiometry: 1.0
species: 747173

780940
type: SpeciesReference
stoichiometry: 2.0
species: 741259

780976
type: SpeciesReference
stoichiometry: 1.0
species: 728812

728812
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Methyltetrahydrofolate_C20H24N7O6

780964
type: SpeciesReference
stoichiometry: 1.0
species: 747099

780928
type: SpeciesReference
stoichiometry: 1.0
species: 746605

033221
type: Reaction
name: Phytanoyl-CoA dioxygenase, peroxisomal
reversible: false
product: 779230
is: http://identifiers.org/ec-code/1.14.11.18
is: ENSCAFG00000023441.1
reactant: 779218
is: ENSCAFG00000023349.1
is: ENSCAFG00000004747.2
product: 779242
notes: R_PHYHx subsystem: Fatty acid oxidation, peroxisome R_PHYHx equation: [x] : akg + o2 + phytcoa --> co2 + phyt2ohcoa + succ
reactant: 779194
product: 779254
reactant: 779206
fast: false

779230
type: SpeciesReference
stoichiometry: 1.0
species: 734030

779218
type: SpeciesReference
stoichiometry: 1.0
species: 731453

731453
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _2-Oxoglutarate_C5H4O5

779242
type: SpeciesReference
stoichiometry: 1.0
species: 751675

751675
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Succinate_C4H4O4

779194
type: SpeciesReference
stoichiometry: 1.0
species: 747758

779254
type: SpeciesReference
stoichiometry: 1.0
species: 749140

749140
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _2-Hydroxyphytanoyl-CoA_C41H70N7O18P3S

779206
type: SpeciesReference
stoichiometry: 1.0
species: 749188

753906
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _24-Hydroxycholesterol_C27H46O2

031270
type: Reaction
reactant: 761573
product: 761659
fast: false
reversible: false
product: 761732
product: 761671
reactant: 761635
reactant: 761598
product: 761695
product: 761683
is: ENSCAFG00000002632.2
product: 761719
reactant: 761585
notes: R_M4BET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4BET2er equation: [r] : mem2emgacpail_hs + pe_hs --> dag_hs + m(em)3gacpail_hs R_H6ET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6ET3er equation: [r] : m2emgacpail_hs + pe_hs --> dag_hs + em2emgacpail_hs R_H6_APOS_ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6_APOS_ET2er equation: [r] : em3gacpail_hs + pe_hs --> dag_hs + emem2gacpail_hs R_H7ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7ET2er equation: [r] : em2emgacpail_hs + pe_hs --> dag_hs + gpi_hs R_H4ET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H4ET3er equation: [r] : m3gacpail_hs + pe_hs --> dag_hs + em3gacpail_hs R_M4CET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4CET3er equation: [r] : m3emgacpail_hs + pe_hs --> dag_hs + mem2emgacpail_hs
product: 761707
reactant: 761610
reactant: 761647
reactant: 761623

761573
type: SpeciesReference
stoichiometry: 1.0
species: 737642

761659
type: SpeciesReference
stoichiometry: 1.0
species: 737642

761732
type: SpeciesReference
stoichiometry: 1.0
species: 737618

761671
type: SpeciesReference
stoichiometry: 1.0
species: 740651

761635
type: SpeciesReference
stoichiometry: 1.0
species: 745519

745519
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (trimannosyl),(phosphoethanolaminyl)-mannosyl-glucosaminyl-acylphosphatidylinositol (M4C)_C57H104N2O37P2FULLRCO2FULLR2CO2

761598
type: SpeciesReference
stoichiometry: 1.0
species: 745471

761695
type: SpeciesReference
stoichiometry: 1.0
species: 746146

761683
type: SpeciesReference
stoichiometry: 6.0
species: 735445

761719
type: SpeciesReference
stoichiometry: 1.0
species: 745832

761585
type: SpeciesReference
stoichiometry: 6.0
species: 748886

761707
type: SpeciesReference
stoichiometry: 1.0
species: 737654

761610
type: SpeciesReference
stoichiometry: 1.0
species: 745531

761647
type: SpeciesReference
stoichiometry: 1.0
species: 737618

761623
type: SpeciesReference
stoichiometry: 1.0
species: 746146

744880
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Leukotriene C4_C30H45N3O9S

747343
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Ammonium_H4N

753579
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Uridine_C9H12N2O6

035744
type: Reaction
notes: R_GLYOX subsystem: Pyruvate Metabolism R_GLYOX equation: [c] : h2o + lgt-S --> gthrd + h + lac-D R_GLYOXm subsystem: Pyruvate Metabolism R_GLYOXm equation: [m] : h2o + lgt-S --> gthrd + h + lac-D
is: ENSCAFG00000019490.2
reactant: 802579
reactant: 802567
product: 802628
product: 802592
reactant: 802554
reactant: 802542
fast: false
is: http://identifiers.org/ec-code/3.1.2.6
product: 802616
product: 802652
product: 802604
product: 802640
reversible: false

802579
type: SpeciesReference
stoichiometry: 1.0
species: 745025

745025
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: (R)-S-Lactoylglutathione_C13H20N3O8S

802567
type: SpeciesReference
stoichiometry: 1.0
species: 741151

802628
type: SpeciesReference
stoichiometry: 1.0
species: 741308

802592
type: SpeciesReference
stoichiometry: 1.0
species: 744624

802554
type: SpeciesReference
stoichiometry: 1.0
species: 745013

802542
type: SpeciesReference
stoichiometry: 1.0
species: 741199

802616
type: SpeciesReference
stoichiometry: 1.0
species: 740946

802652
type: SpeciesReference
stoichiometry: 1.0
species: 741259

802604
type: SpeciesReference
stoichiometry: 1.0
species: 740922

802640
type: SpeciesReference
stoichiometry: 1.0
species: 744598

040477
type: Reaction
notes: R_SPMS subsystem: Urea cycle/amino group metabolism R_SPMS equation: [c] : ametam + ptrc --> 5mta + h + spmd
fast: false
is: ENSCAFG00000016733.2
product: 847378
reactant: 847353
product: 847390
name: spermidine synthase
reversible: false
is: http://identifiers.org/ec-code/2.5.1.16
reactant: 847365
product: 847402

847378
type: SpeciesReference
stoichiometry: 1.0
species: 728800

847353
type: SpeciesReference
stoichiometry: 1.0
species: 750249

750249
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Putrescine_C4H14N2

847390
type: SpeciesReference
stoichiometry: 1.0
species: 751410

847365
type: SpeciesReference
stoichiometry: 1.0
species: 731743

847402
type: SpeciesReference
stoichiometry: 1.0
species: 741259

729282
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-2-Aminoadipate_C6H10NO4

040043
type: Reaction
is: ENSCAFG00000010279.2
reactant: 842614
reactant: 842578
product: 842712
product: 842651
reactant: 842566
product: 842675
reversible: false
reactant: 842639
fast: false
reactant: 842602
product: 842724
notes: R_P45017A4r subsystem: Steroid Metabolism R_P45017A4r equation: [r] : 17ahprgstrn + h + nadph + (0.5) o2 --> acald + andrstndn + h2o + nadp R_P45017A2r subsystem: Steroid Metabolism R_P45017A2r equation: [r] : 17ahprgnlone + h + nadph + (0.5) o2 --> acald + dhea + h2o + nadp R_P45017A1r subsystem: Steroid Metabolism R_P45017A1r equation: [r] : h + nadph + o2 + prgnlone --> 17ahprgnlone + h2o + nadp R_P45017A3r subsystem: Steroid Metabolism R_P45017A3r equation: [r] : h + nadph + o2 + prgstrn --> 17ahprgstrn + h2o + nadp
reactant: 842590
product: 842663
is: http://identifiers.org/ec-code/1.14.99.9
product: 842700
reactant: 842626
product: 842687

842614
type: SpeciesReference
stoichiometry: 1.0
species: 726536

726536
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _17alpha-Hydroxypregnenolone_C21H32O3

842578
type: SpeciesReference
stoichiometry: 1.0
species: 749743

749743
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Progesterone_C21H30O2

842712
type: SpeciesReference
stoichiometry: 1.0
species: 726536

842651
type: SpeciesReference
stoichiometry: 2.0
species: 730100

842566
type: SpeciesReference
stoichiometry: 3.0
species: 747746

842675
type: SpeciesReference
stoichiometry: 4.0
species: 741223

842639
type: SpeciesReference
stoichiometry: 1.0
species: 726560

726560
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _17alpha-Hydroxyprogesterone_C21H30O3

842602
type: SpeciesReference
stoichiometry: 4.0
species: 747209

842724
type: SpeciesReference
stoichiometry: 1.0
species: 726560

842590
type: SpeciesReference
stoichiometry: 1.0
species: 749695

749695
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Pregnenolone_C21H32O2

842663
type: SpeciesReference
stoichiometry: 1.0
species: 736279

736279
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dehydroepiandrosterone_C19H28O2

842700
type: SpeciesReference
stoichiometry: 4.0
species: 747148

842626
type: SpeciesReference
stoichiometry: 4.0
species: 741332

842687
type: SpeciesReference
stoichiometry: 1.0
species: 731852

731852
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Androstenedione_C19H26O2

728956
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _6-Hydroxymelatonin_C13H16N2O3

745687
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Mannosyl)6-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1660H2728N20O520P20

737411
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-erythro-4-Hydroxyglutamate_C5H8NO5

749502
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Diphosphate_HO7P2

038706
type: Reaction
reactant: 831042
modifier: 831066
modifier: 831114
modifier: 831090
notes: R_ECOAH12m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ECOAH12m equation: [m] : 2mp2coa + h2o <==> 3hibutcoa R_PRPNCOAHYDm subsystem: beta-Alanine metabolism R_PRPNCOAHYDm equation: [m] : h2o + prpncoa --> 3hpcoa R_ECOAH9m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ECOAH9m equation: [m] : 2mb2coa + h2o <==> 3hmbcoa R_ECOAH1m subsystem: Tryptophan metabolism R_ECOAH1m equation: [m] : 3hbcoa <==> b2coa + h2o
is: http://identifiers.org/ec-code/4.2.1.17
is: ENSCAFG00000013411.2
fast: false
modifier: 831078
product: 831054
modifier: 831126
modifier: 831102
reactant: 831029
reversible: false
modifier: 831138

831042
type: SpeciesReference
stoichiometry: 1.0
species: 750104

750104
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Propenoyl-CoA_C24H34N7O17P3S

727408
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113

831054
type: SpeciesReference
stoichiometry: 1.0
species: 727456

727456
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3-Hydroxypropionyl-CoA_C24H36N7O18P3S

726997
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113

831029
type: SpeciesReference
stoichiometry: 1.0
species: 741199

732599
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: (R)-3-Hydroxybutanoate_C4H7O3

041081
type: Reaction
reversible: false
is: ENSCAFG00000006607.2
is: http://identifiers.org/ec-code/3.5.2.2
product: 854412
name: dihydropyrimidinase (5,6-dihydrouracil)
notes: R_DHPM1 subsystem: Pyrimidine Catabolism R_DHPM1 equation: [c] : 56dura + h2o --> cala + h
is: ENSCAFG00000000676.2
is: ENSCAFG00000008753.2
fast: false
reactant: 854400
reactant: 854388
product: 854424

854412
type: SpeciesReference
stoichiometry: 1.0
species: 733021

854400
type: SpeciesReference
stoichiometry: 1.0
species: 741151

854388
type: SpeciesReference
stoichiometry: 1.0
species: 728402

728402
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5,6-dihydrouracil_C4H6N2O2

854424
type: SpeciesReference
stoichiometry: 1.0
species: 741259

749490
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Diphosphate_HO7P2

748783
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Phosphocreatine_C4H9N3O5P

742528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Hypoxanthine_C5H4N4O

740493
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: ganglioside GM2 (homo sapiens)_C49H85N3O25FULLRCO

744844
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Leukotriene B4_C20H31O4

032174
type: Reaction
is: ENSCAFG00000009034.2
reactant: 770425
notes: R_NCCt subsystem: Transport, Extracellular R_NCCt equation: cl[e] + na1[e] --> cl[c] + na1[c]
product: 770462
reversible: false
product: 770449
name: Na+-Cl- cotransport
reactant: 770437
fast: false

770425
type: SpeciesReference
stoichiometry: 1.0
species: 746930

770462
type: SpeciesReference
stoichiometry: 1.0
species: 746918

770449
type: SpeciesReference
stoichiometry: 1.0
species: 733738

770437
type: SpeciesReference
stoichiometry: 1.0
species: 733750

747878
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: _9-O-Acetylated GD3 (homo sapiens)_C54H90N3O29FULLRCO

735505
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: dATP_C10H12N5O12P3

730355
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)3 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)1 (Cer)1_C72H125N4O41FULLRCO

750466
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Quinolinate_C7H3NO4

733201
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: CDP_C9H12N3O11P2

742708
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: IDP_C10H11N4O11P2

730657
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: N-Acetylneuraminate_C11H18NO9

031246
type: Reaction
fast: false
reactant: 761477
is: http://identifiers.org/ec-code/3.1.1.47
product: 761489
is: ENSCAFG00000011135.1
product: 761513
reactant: 761465
product: 761501
reversible: false
name: Platelet-activating factor acetylhydrolase
notes: R_PAFHe subsystem: Glycerophospholipid Metabolism R_PAFHe equation: [e] : h2o + paf_hs --> ac + ak2lgchol_hs + h

761477
type: SpeciesReference
stoichiometry: 1.0
species: 741163

761489
type: SpeciesReference
stoichiometry: 1.0
species: 729991

729991
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Acetate_C2H3O2

761513
type: SpeciesReference
stoichiometry: 1.0
species: 731381

731381
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _1-alkyl 2-lysoglycerol 3-phosphocholine_C10H21O5NPFULLR

761465
type: SpeciesReference
stoichiometry: 1.0
species: 748399

748399
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens)_C11H23O4NPFULLRCO2

761501
type: SpeciesReference
stoichiometry: 1.0
species: 741271

727528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Iodo-L-tyrosine_C9H10INO3

752241
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Tetrahydrobiopterin_C9H15N5O3

740059
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: gamma-L-Glutamyl-L-cysteine_C8H13N2O5S

031921
type: Reaction
is: ENSCAFG00000003837.1
modifier: 768282
is: http://identifiers.org/ec-code/1.2.1.25
reactant: 768090
is: http://identifiers.org/ec-code/1.2.4.2
reversible: false
product: 768222
is: http://identifiers.org/ec-code/1.8.1.4
product: 768162
reactant: 768126
modifier: 768294
reactant: 768029
modifier: 768330
product: 768198
notes: R_GCCbim subsystem: Glycine, Serine, and Threonine Metabolism R_GCCbim equation: [m] : alpro + thf --> dhlpro + mlthf + nh4 R_PDHm subsystem: Glycolysis/Gluconeogenesis R_PDHm equation: [m] : coa + nad + pyr --> accoa + co2 + nadh R_OIVD2m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD2m equation: [m] : 3mob + coa + nad --> co2 + ibcoa + nadh R_2OXOADOXm subsystem: Lysine Metabolism R_2OXOADOXm equation: [m] : 2oxoadp + coa + nad --> co2 + glutcoa + nadh R_GCCcm subsystem: Glycine, Serine, and Threonine Metabolism R_GCCcm equation: [m] : dhlpro + nad <==> h + lpro + nadh R_GCC2bim subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2bim equation: [m] : alpam + thf --> dhlam + mlthf + nh4 R_OIVD3m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD3m equation: [m] : 3mop + coa + nad --> 2mbcoa + co2 + nadh R_GCCam subsystem: Glycine, Serine, and Threonine Metabolism R_GCCam equation: [m] : gly + h + lpro <==> alpro + co2 R_GCC2cm subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2cm equation: [m] : dhlam + nad <==> h + lpam + nadh R_OIVD1m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD1m equation: [m] : 4mop + coa + nad --> co2 + ivcoa + nadh R_GCC2am subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2am equation: [m] : gly + h + lpam <==> alpam + co2 R_AKGDm subsystem: Citric Acid Cycle R_AKGDm equation: [m] : akg + coa + nad --> co2 + nadh + succoa
reactant: 768005
product: 768246
modifier: 768342
product: 768258
modifier: 768366
modifier: 768354
modifier: 768402
product: 768210
reactant: 768078
modifier: 768378
reactant: 768017
reactant: 768102
reactant: 768114
is: http://identifiers.org/ec-code/2.1.2.10
product: 768150
reactant: 768041
modifier: 768306
product: 768138
product: 768186
modifier: 768318
is: http://identifiers.org/ec-code/1.2.4.1
product: 768174
product: 768270
is: http://identifiers.org/ec-code/1.4.4.2
product: 768234
fast: false
reactant: 768054
reactant: 768066
modifier: 768390

731670
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: S-Aminomethyldihydrolipoylprotein_CH6NS2X

768090
type: SpeciesReference
stoichiometry: 2.0
species: 752374

768222
type: SpeciesReference
stoichiometry: 1.0
species: 730148

768162
type: SpeciesReference
stoichiometry: 1.0
species: 726973

768126
type: SpeciesReference
stoichiometry: 6.0
species: 747002

736376
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Dihydrolipoamide_C8H17NOS2

768029
type: SpeciesReference
stoichiometry: 1.0
species: 731658

731658
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: S-aminomethyldihydrolipoamide_C9H21N2OS2

768198
type: SpeciesReference
stoichiometry: 1.0
species: 736388

736388
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Dihydrolipolprotein_H2S2X

768005
type: SpeciesReference
stoichiometry: 1.0
species: 727034

768246
type: SpeciesReference
stoichiometry: 1.0
species: 742612

742612
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Isobutyryl-CoA_C25H38N7O17P3S

768258
type: SpeciesReference
stoichiometry: 2.0
species: 746617

745363
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Lipoylprotein_S2X

768210
type: SpeciesReference
stoichiometry: 2.0
species: 747319

768078
type: SpeciesReference
stoichiometry: 1.0
species: 731429

768017
type: SpeciesReference
stoichiometry: 1.0
species: 728209

728209
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _4-Methyl-2-oxopentanoate_C6H9O3

768102
type: SpeciesReference
stoichiometry: 1.0
species: 750393

768114
type: SpeciesReference
stoichiometry: 1.0
species: 727636

727636
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: (S)-3-Methyl-2-oxopentanoate_C6H9O3

768150
type: SpeciesReference
stoichiometry: 1.0
species: 743060

768041
type: SpeciesReference
stoichiometry: 1.0
species: 731670

768138
type: SpeciesReference
stoichiometry: 1.0
species: 751687

768186
type: SpeciesReference
stoichiometry: 1.0
species: 740120

768174
type: SpeciesReference
stoichiometry: 6.0
species: 734005

768270
type: SpeciesReference
stoichiometry: 6.0
species: 747062

768234
type: SpeciesReference
stoichiometry: 1.0
species: 736376

768054
type: SpeciesReference
stoichiometry: 1.0
species: 727612

727612
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3-Methyl-2-oxobutanoate_C5H7O3

768066
type: SpeciesReference
stoichiometry: 6.0
species: 734091

734247
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Creatine_C4H9N3O2

035529
type: Reaction
product: 801088
fast: false
reactant: 801064
product: 801100
is: http://identifiers.org/ec-code/3.5.4.12
reactant: 801052
is: ENSCAFG00000007951.2
reversible: true
name: dCMP deaminase
reactant: 801076
notes: R_DCMPDA subsystem: Pyrimidine Catabolism R_DCMPDA equation: [c] : dcmp + h + h2o <==> dump + nh4

801088
type: SpeciesReference
stoichiometry: 1.0
species: 747294

801064
type: SpeciesReference
stoichiometry: 1.0
species: 735601

801100
type: SpeciesReference
stoichiometry: 1.0
species: 737290

801052
type: SpeciesReference
stoichiometry: 1.0
species: 741151

801076
type: SpeciesReference
stoichiometry: 1.0
species: 741259

033815
type: Reaction
is: ENSCAFG00000000644.2
reactant: 783922
fast: false
product: 783947
notes: R_PI345P5P subsystem: Inositol Phosphate Metabolism R_PI345P5P equation: [c] : h2o + pail345p_hs --> pail34p_hs + pi R_PI45P5P subsystem: Inositol Phosphate Metabolism R_PI45P5P equation: [c] : h2o + pail45p_hs --> pail4p_hs + pi
reactant: 783897
is: http://identifiers.org/ec-code/3.1.3.36
reactant: 783910
reversible: false
product: 783934
product: 783959

783922
type: SpeciesReference
stoichiometry: 2.0
species: 741151

783947
type: SpeciesReference
stoichiometry: 1.0
species: 748531

783897
type: SpeciesReference
stoichiometry: 1.0
species: 748411

783910
type: SpeciesReference
stoichiometry: 1.0
species: 748507

783934
type: SpeciesReference
stoichiometry: 2.0
species: 749200

783959
type: SpeciesReference
stoichiometry: 1.0
species: 748435

030597
type: Reaction
reactant: 755996
product: 756056
is: ENSCAFG00000003961.2
product: 756044
product: 756032
reactant: 756020
notes: R_SLCBK1 subsystem: Sphingolipid Metabolism R_SLCBK1 equation: [c] : atp + sphgn --> adp + h + sph1p R_SPHK21c subsystem: Sphingolipid Metabolism R_SPHK21c equation: [c] : atp + sphings --> adp + h + sphs1p
fast: false
reactant: 756008
product: 756068
reversible: false

755996
type: SpeciesReference
stoichiometry: 2.0
species: 732441

756056
type: SpeciesReference
stoichiometry: 2.0
species: 730922

756044
type: SpeciesReference
stoichiometry: 1.0
species: 751385

751385
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Sphingosine 1-phosphate_C18H37NO5P

756032
type: SpeciesReference
stoichiometry: 1.0
species: 751263

756020
type: SpeciesReference
stoichiometry: 1.0
species: 751288

756008
type: SpeciesReference
stoichiometry: 1.0
species: 751312

751312
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Sphingosine_C18H38NO2

756068
type: SpeciesReference
stoichiometry: 2.0
species: 741259

738930
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C82H137N2O65X

735373
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dADP_C10H12N5O9P2

743963
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 33_C233H372N16O197S10X

040140
type: Reaction
product: 843612
reactant: 843552
is: ENSCAFG00000012081.2
reversible: false
product: 843600
product: 843588
reactant: 843564
fast: false
notes: R_PCm subsystem: Pyruvate Metabolism R_PCm equation: [m] : atp + hco3 + pyr --> adp + h + oaa + pi
name: pyruvate carboxylase
is: http://identifiers.org/ec-code/6.4.1.1
product: 843576
reactant: 843540

843612
type: SpeciesReference
stoichiometry: 1.0
species: 741308

843552
type: SpeciesReference
stoichiometry: 1.0
species: 732465

843600
type: SpeciesReference
stoichiometry: 1.0
species: 730946

843588
type: SpeciesReference
stoichiometry: 1.0
species: 749249

843564
type: SpeciesReference
stoichiometry: 1.0
species: 750393

843576
type: SpeciesReference
stoichiometry: 1.0
species: 747842

747842
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Oxaloacetate_C4H2O5

843540
type: SpeciesReference
stoichiometry: 1.0
species: 741440

741440
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Bicarbonate_CHO3

040104
type: Reaction
product: 843322
product: 843310
reversible: false
product: 843238
product: 843226
product: 843274
product: 843262
notes: R_THRt4 subsystem: Transport, Extracellular R_THRt4 equation: na1[e] + thr-L[e] --> na1[c] + thr-L[c] R_LEUt4 subsystem: Transport, Extracellular R_LEUt4 equation: leu-L[e] + na1[e] --> leu-L[c] + na1[c] R_SERt4 subsystem: Transport, Extracellular R_SERt4 equation: na1[e] + ser-L[e] --> na1[c] + ser-L[c] R_ALAt4 subsystem: Transport, Extracellular R_ALAt4 equation: ala-L[e] + na1[e] --> ala-L[c] + na1[c] R_PROt4 subsystem: Transport, Extracellular R_PROt4 equation: na1[e] + pro-L[e] --> na1[c] + pro-L[c] R_ASNt4 subsystem: Transport, Extracellular R_ASNt4 equation: asn-L[e] + na1[e] --> asn-L[c] + na1[c] R_METt4 subsystem: Transport, Extracellular R_METt4 equation: met-L[e] + na1[e] --> met-L[c] + na1[c] R_GLYt4 subsystem: Transport, Extracellular R_GLYt4 equation: gly[e] + na1[e] --> gly[c] + na1[c] R_PHEt4 subsystem: Transport, Extracellular R_PHEt4 equation: na1[e] + phe-L[e] --> na1[c] + phe-L[c] R_GLNt4 subsystem: Transport, Extracellular R_GLNt4 equation: gln-L[e] + na1[e] --> gln-L[c] + na1[c]
reactant: 843116
reactant: 843190
reactant: 843080
fast: false
product: 843298
product: 843214
reactant: 843129
product: 843250
reactant: 843166
reactant: 843202
product: 843334
reactant: 843104
reactant: 843141
is: ENSCAFG00000009286.2
reactant: 843092
product: 843286
reactant: 843153
reactant: 843178

843322
type: SpeciesReference
stoichiometry: 1.0
species: 749031

843310
type: SpeciesReference
stoichiometry: 1.0
species: 731549

843238
type: SpeciesReference
stoichiometry: 1.0
species: 739926

843226
type: SpeciesReference
stoichiometry: 1.0
species: 751082

843274
type: SpeciesReference
stoichiometry: 1.0
species: 746291

843262
type: SpeciesReference
stoichiometry: 1.0
species: 732332

843116
type: SpeciesReference
stoichiometry: 1.0
species: 746303

843190
type: SpeciesReference
stoichiometry: 1.0
species: 751094

843080
type: SpeciesReference
stoichiometry: 1.0
species: 744796

843298
type: SpeciesReference
stoichiometry: 1.0
species: 752483

843214
type: SpeciesReference
stoichiometry: 1.0
species: 740168

843129
type: SpeciesReference
stoichiometry: 10.0
species: 746930

843250
type: SpeciesReference
stoichiometry: 10.0
species: 746918

843166
type: SpeciesReference
stoichiometry: 1.0
species: 752496

843202
type: SpeciesReference
stoichiometry: 1.0
species: 749043

843334
type: SpeciesReference
stoichiometry: 1.0
species: 749875

843104
type: SpeciesReference
stoichiometry: 1.0
species: 732344

843141
type: SpeciesReference
stoichiometry: 1.0
species: 749887

843092
type: SpeciesReference
stoichiometry: 1.0
species: 731561

843286
type: SpeciesReference
stoichiometry: 1.0
species: 744784

843153
type: SpeciesReference
stoichiometry: 1.0
species: 740180

843178
type: SpeciesReference
stoichiometry: 1.0
species: 739939

727709
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _3-Oxohexadecanoyl-CoA_C37H60N7O18P3S

737202
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dithiothreitol_C4H10O2S2

732829
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Biotin_C10H15N2O3S

037822
type: Reaction
reactant: 822899
product: 822935
fast: false
reactant: 822923
notes: R_ACSRTNMT subsystem: Tryptophan metabolism R_ACSRTNMT equation: [c] : Nacsertn + amet --> ahcys + h + melatn R_ACSOMT subsystem: Tryptophan metabolism R_ACSOMT equation: [c] : 5hoxindoa + amet --> 5moxact + ahcys + h
reactant: 822911
product: 822948
is: ENSCAFG00000024670.1
product: 822960
is: http://identifiers.org/ec-code/2.1.1.4
reversible: false
product: 822972

822899
type: SpeciesReference
stoichiometry: 2.0
species: 731694

822935
type: SpeciesReference
stoichiometry: 2.0
species: 731273

822923
type: SpeciesReference
stoichiometry: 1.0
species: 728692

822911
type: SpeciesReference
stoichiometry: 1.0
species: 729404

822948
type: SpeciesReference
stoichiometry: 1.0
species: 746134

746134
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Melatonin_C13H16N2O2

822960
type: SpeciesReference
stoichiometry: 1.0
species: 728788

728788
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Methoxyindoleacetate_C11H10NO3

822972
type: SpeciesReference
stoichiometry: 2.0
species: 741259

729810
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: S-Formylglutathione_C11H16N3O7S

728752
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Hydroxykynurenine_C10H12N2O4

752777
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Trehalose_C12H22O11

746461
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: _1D-myo-Inositol 1,4,5,6-tetrakisphosphate_C6H8O18P4

748097
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Octadecenoyl-CoA (n-C18:1CoA)_C39H64N7O17P3S

035275
type: Reaction
notes: R_PDE4g subsystem: Nucleotides R_PDE4g equation: [g] : 35cgmp + h2o --> gmp + h R_PDE1 subsystem: Nucleotides R_PDE1 equation: [c] : camp + h2o --> amp + h R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h R_PDE1g subsystem: Nucleotides R_PDE1g equation: [g] : camp + h2o --> amp + h
reactant: 799040
reactant: 799028
fast: false
reactant: 798992
product: 799076
product: 799052
product: 799100
is: ENSCAFG00000000795.2
reactant: 798980
reversible: false
reactant: 799004
is: http://identifiers.org/ec-code/3.1.4.17
product: 799088
product: 799064
product: 799112
reactant: 799016

799040
type: SpeciesReference
stoichiometry: 2.0
species: 741151

799028
type: SpeciesReference
stoichiometry: 1.0
species: 727190

727190
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3',5'-Cyclic GMP_C10H11N5O7P

798992
type: SpeciesReference
stoichiometry: 1.0
species: 727214

799076
type: SpeciesReference
stoichiometry: 2.0
species: 741283

799052
type: SpeciesReference
stoichiometry: 1.0
species: 740530

740530
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: GMP_C10H12N5O8P

799100
type: SpeciesReference
stoichiometry: 1.0
species: 731755

798980
type: SpeciesReference
stoichiometry: 1.0
species: 733033

733033
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cAMP_C10H11N5O6P

799004
type: SpeciesReference
stoichiometry: 2.0
species: 741175

799088
type: SpeciesReference
stoichiometry: 1.0
species: 740554

740554
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GMP_C10H12N5O8P

799064
type: SpeciesReference
stoichiometry: 1.0
species: 731779

799112
type: SpeciesReference
stoichiometry: 2.0
species: 741259

799016
type: SpeciesReference
stoichiometry: 1.0
species: 733057

733057
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: cAMP_C10H11N5O6P

752313
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: trihexosyl ceramide (homo sapiens)_C36H66NO17FULLRCO

039731
type: Reaction
product: 840327
reactant: 840303
fast: false
product: 840339
notes: R_GMPR subsystem: Nucleotides R_GMPR equation: [c] : gmp + (2) h + nadph --> imp + nadp + nh4
product: 840351
name: GMP reductase
reactant: 840315
is: ENSCAFG00000012127.2
is: http://identifiers.org/ec-code/1.7.1.7
is: ENSCAFG00000009920.2
reactant: 840291
reversible: false

840327
type: SpeciesReference
stoichiometry: 1.0
species: 747294

840303
type: SpeciesReference
stoichiometry: 2.0
species: 741259

840339
type: SpeciesReference
stoichiometry: 1.0
species: 747099

840351
type: SpeciesReference
stoichiometry: 1.0
species: 742843

840315
type: SpeciesReference
stoichiometry: 1.0
species: 747173

840291
type: SpeciesReference
stoichiometry: 1.0
species: 740530

737762
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _16-Glucuronide-estriol_C24H32O9

032751
type: Reaction
is: ENSCAFG00000006034.2
reactant: 775812
fast: false
modifier: 775946
modifier: 775910
is: http://identifiers.org/ec-code/6.2.1.3
reactant: 775824
modifier: 775934
product: 775848
reversible: false
modifier: 775885
is: ENSCAFG00000018063.2
product: 775860
product: 775836
reactant: 775800
modifier: 775922
modifier: 775872
modifier: 775958
modifier: 775898
notes: R_FACOAL150 subsystem: Fatty acid activation R_FACOAL150 equation: [c] : atp + coa + ptdca <==> amp + ppi + ptdcacoa R_FACOAL204i subsystem: Fatty acid activation R_FACOAL204i equation: [c] : arachd + atp + coa --> amp + arachdcoa + ppi R_FACOAL170 subsystem: Fatty acid activation R_FACOAL170 equation: [c] : atp + coa + hpdca <==> amp + hpdcacoa + ppi

775812
type: SpeciesReference
stoichiometry: 1.0
species: 732152

775824
type: SpeciesReference
stoichiometry: 1.0
species: 732441

775848
type: SpeciesReference
stoichiometry: 1.0
species: 731755

775860
type: SpeciesReference
stoichiometry: 1.0
species: 749466

775836
type: SpeciesReference
stoichiometry: 1.0
species: 732188

775800
type: SpeciesReference
stoichiometry: 1.0
species: 734054

030981
type: Reaction
reactant: 759341
reversible: true
product: 759353
product: 759378
name: phosphatidylcholine transporter
notes: R_PCt subsystem: Transport, Extracellular R_PCt equation: atp[c] + h2o[c] + pchol_hs[c] <==> adp[c] + h[c] + pchol_hs[e] + pi[c]
is: ENSCAFG00000001833.2
product: 759366
fast: false
product: 759390
reactant: 759317
reactant: 759329

759341
type: SpeciesReference
stoichiometry: 1.0
species: 732441

759353
type: SpeciesReference
stoichiometry: 1.0
species: 730922

759378
type: SpeciesReference
stoichiometry: 1.0
species: 748711

759366
type: SpeciesReference
stoichiometry: 1.0
species: 749200

759390
type: SpeciesReference
stoichiometry: 1.0
species: 741259

759317
type: SpeciesReference
stoichiometry: 1.0
species: 748699

759329
type: SpeciesReference
stoichiometry: 1.0
species: 741151

037641
type: Reaction
reactant: 821113
reactant: 821016
is: ENSCAFG00000014435.2
reactant: 821028
reactant: 821052
product: 821270
product: 821161
product: 821137
reactant: 820980
is: http://identifiers.org/ec-code/1.4.3.6
product: 821173
product: 821149
fast: false
reactant: 821077
reactant: 821101
product: 821197
product: 821185
product: 821282
reactant: 821125
reactant: 821089
product: 821258
reactant: 820968
product: 821294
is: http://identifiers.org/ec-code/1.4.3.4
product: 821245
reactant: 820992
notes: R_3MOXTYROX subsystem: Tyrosine metabolism R_3MOXTYROX equation: [c] : 3moxtyr + h2o + o2 --> 3mox4hpac + h2o2 + nh4 R_MAOLNOR subsystem: Tyrosine metabolism R_MAOLNOR equation: [c] : h2o + normete-L + o2 --> 3m4hpga + h2o2 + nh4 R_APRTO2 subsystem: Arginine and Proline Metabolism R_APRTO2 equation: [c] : aprut + h2o + o2 --> h2o2 + n4abutn + nh4 R_42A12BOOX subsystem: Tyrosine metabolism R_42A12BOOX equation: [c] : dopa + h2o + o2 --> 34dhpac + h2o2 + nh4 R_PEAMNO subsystem: Phenylalanine metabolism R_PEAMNO equation: [c] : h2o + o2 + peamn --> h2o2 + nh4 + pacald R_3HXKYNOXDA subsystem: Tryptophan metabolism R_3HXKYNOXDA equation: [c] : 3hxkynam + o2 --> 48dhoxquin + h2o2 + nh4 R_41R2A1H12BOOX subsystem: Tyrosine metabolism R_41R2A1H12BOOX equation: [c] : h2o + nrpphr + o2 --> 34dhmald + h2o2 + nh4 R_TRYPTAOX subsystem: Tryptophan metabolism R_TRYPTAOX equation: [c] : h2o + o2 + trypta --> h2o2 + id3acald + nh4 R_5HXKYNOXDA subsystem: Tryptophan metabolism R_5HXKYNOXDA equation: [c] : 5hxkynam + o2 --> 46dhoxquin + h2o2 + nh4 R_TYROXDAc subsystem: Tyrosine metabolism R_TYROXDAc equation: [c] : h2o + o2 + tym --> 4hoxpacd + h2o2 + nh4 R_5HOXINOXDA subsystem: Tryptophan metabolism R_5HOXINOXDA equation: [c] : h2o + o2 + srtn --> 5hoxindact + h2o2 + nh4 R_41R1H2MAE12BOOX subsystem: Tyrosine metabolism R_41R1H2MAE12BOOX equation: [c] : adrnl + h2o + o2 --> 34dhmald + h2o2 + mma
product: 821209
reactant: 821064
product: 821221
reactant: 821004
reversible: false
reactant: 821040
product: 821233

821113
type: SpeciesReference
stoichiometry: 12.0
species: 747698

821016
type: SpeciesReference
stoichiometry: 1.0
species: 753047

821028
type: SpeciesReference
stoichiometry: 1.0
species: 727672

821052
type: SpeciesReference
stoichiometry: 1.0
species: 728764

728764
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Hydroxykynurenamine_C9H13N2O2

821270
type: SpeciesReference
stoichiometry: 1.0
species: 727942

727942
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4,8-Dihydroxyquinoline_C9H7NO2

821161
type: SpeciesReference
stoichiometry: 1.0
species: 728125

728125
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Hydroxyphenylacetaldehyde_C8H8O2

821137
type: SpeciesReference
stoichiometry: 1.0
species: 727660

727660
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Methoxy-4-hydroxyphenylacetaldehyde_C9H10O3

820980
type: SpeciesReference
stoichiometry: 1.0
species: 747528

821173
type: SpeciesReference
stoichiometry: 1.0
species: 727118

727118
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3,4-Dihydroxyphenylacetaldehyde_C8H8O3

821149
type: SpeciesReference
stoichiometry: 1.0
species: 746882

821077
type: SpeciesReference
stoichiometry: 1.0
species: 727516

727516
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Hydroxykynurenamine_C9H13N2O2

821101
type: SpeciesReference
stoichiometry: 10.0
species: 741151

821197
type: SpeciesReference
stoichiometry: 1.0
species: 746629

746629
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Methylamine_C1H6N

821185
type: SpeciesReference
stoichiometry: 11.0
species: 747294

821282
type: SpeciesReference
stoichiometry: 2.0
species: 727082

727082
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3,4-Dihydroxymandelaldehyde_C8H8O4

821125
type: SpeciesReference
stoichiometry: 1.0
species: 732032

821089
type: SpeciesReference
stoichiometry: 1.0
species: 736983

821258
type: SpeciesReference
stoichiometry: 1.0
species: 742660

820968
type: SpeciesReference
stoichiometry: 1.0
species: 747553

821294
type: SpeciesReference
stoichiometry: 1.0
species: 727929

821245
type: SpeciesReference
stoichiometry: 12.0
species: 741078

820992
type: SpeciesReference
stoichiometry: 1.0
species: 731164

821209
type: SpeciesReference
stoichiometry: 1.0
species: 727540

821064
type: SpeciesReference
stoichiometry: 1.0
species: 751446

821221
type: SpeciesReference
stoichiometry: 1.0
species: 728668

821004
type: SpeciesReference
stoichiometry: 1.0
species: 752854

752854
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Tryptamine_C10H13N2

821040
type: SpeciesReference
stoichiometry: 1.0
species: 748898

748898
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Phenethylamine_C8H12N

821233
type: SpeciesReference
stoichiometry: 1.0
species: 748375

748375
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Phenylacetaldehyde_C8H8O

746641
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: (R)-Methylmalonyl-CoA_C25H35N7O19P3S

034589
type: Reaction
is: http://identifiers.org/ec-code/2.7.7.3
product: 791798
reactant: 791762
fast: false
modifier: 791822
notes: R_PTPAT subsystem: CoA Biosynthesis R_PTPAT equation: [c] : atp + h + pan4p <==> dpcoa + ppi R_DPCOAK subsystem: CoA Biosynthesis R_DPCOAK equation: [c] : atp + dpcoa --> adp + coa + h
modifier: 791810
product: 791774
reversible: false
product: 791786
modifier: 791847
is: http://identifiers.org/ec-code/2.7.1.24
modifier: 791835
is: ENSCAFG00000014948.2
reactant: 791750
modifier: 791859

791798
type: SpeciesReference
stoichiometry: 1.0
species: 741259

791762
type: SpeciesReference
stoichiometry: 1.0
species: 732441

737031
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dephospho-CoA_C21H33N7O13P2S

791774
type: SpeciesReference
stoichiometry: 1.0
species: 734054

791786
type: SpeciesReference
stoichiometry: 1.0
species: 730922

748639
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Pantetheine 4'-phosphate_C11H21N2O7PS

791750
type: SpeciesReference
stoichiometry: 1.0
species: 737031

730028
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Acetoacetate_C4H5O3

729392
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Acetyl-L-aspartate_C6H7NO5

040573
type: Reaction
fast: false
product: 849743
notes: R_GLCAT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT5g equation: [g] : cs_e_pre2 + udpglcur --> cs_e_pre3 + h + udp R_GLCAT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT3g equation: [g] : cs_c,d,e_pre1 + udpglcur --> cs_c_pre2 + h + udp R_GLCAT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT4g equation: [g] : cs_d_pre2 + udpglcur --> cs_d_pre3 + h + udp R_GLCAT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT2g equation: [g] : cs_a,b,e_pre1 + udpglcur --> cs_a,b_pre2 + h + udp
reactant: 849683
reactant: 849671
product: 849731
is: ENSCAFG00000004853.2
reversible: false
reactant: 849658
product: 849779
product: 849719
reactant: 849707
reactant: 849695
product: 849767
product: 849755

849743
type: SpeciesReference
stoichiometry: 4.0
species: 753157

849683
type: SpeciesReference
stoichiometry: 1.0
species: 734853

734853
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate D (GlcNAc6S-GlcA2S) precursor 2_C31H46NO34S3X

849671
type: SpeciesReference
stoichiometry: 1.0
species: 734477

849731
type: SpeciesReference
stoichiometry: 1.0
species: 734743

734743
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate C (GalNAc6S-GlcA), precursor 2_C37H54NO37S2X

849658
type: SpeciesReference
stoichiometry: 1.0
species: 734658

849779
type: SpeciesReference
stoichiometry: 1.0
species: 734489

849719
type: SpeciesReference
stoichiometry: 1.0
species: 734866

734866
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 3_C37H53NO40S3X

849707
type: SpeciesReference
stoichiometry: 1.0
species: 734999

849695
type: SpeciesReference
stoichiometry: 4.0
species: 753338

849767
type: SpeciesReference
stoichiometry: 1.0
species: 735011

735011
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 3_C37H52NO43S4X

849755
type: SpeciesReference
stoichiometry: 4.0
species: 741283

752181
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: tetracosatetraenoyl coenzyme A_C45H70N7O17P3S

743757
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 18_C163H262N11O132S5X

742200
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 2_C79H116N5O96S10

742540
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Hypoxanthine_C5H4N4O

037098
type: Reaction
product: 814601
product: 814564
is: ENSCAFG00000001290.2
reactant: 814504
product: 814614
reactant: 814516
notes: R_ARABR subsystem: Pentose and Glucuronate Interconversions R_ARABR equation: [c] : arab-L + h + nadph --> abt + nadp R_LALDO2 subsystem: Pyruvate Metabolism R_LALDO2 equation: [c] : h + mthgxl + nadph --> lald-D + nadp R_ALR3 subsystem: Pyruvate Metabolism R_ALR3 equation: [c] : acetol + h + nadph --> 12ppd-S + nadp R_ALR subsystem: Glycine, Serine, and Threonine Metabolism R_ALR equation: [c] : h2o + mthgxl + nadp --> (2) h + nadph + pyr R_SBTR subsystem: Fructose and Mannose Metabolism R_SBTR equation: [c] : glc-D + h + nadph --> nadp + sbt-D R_GALOR subsystem: Galactose metabolism R_GALOR equation: [c] : gal + h + nadph <==> galt + nadp R_ALR2 subsystem: Pyruvate Metabolism R_ALR2 equation: [c] : h + mthgxl + nadph --> acetol + nadp R_PPDOy subsystem: Pyruvate Metabolism R_PPDOy equation: [c] : h + lald-D + nadph --> 12ppd-R + nadp
modifier: 814699
is: ENSCAFG00000025304.1
reactant: 814456
product: 814552
product: 814540
product: 814639
modifier: 814687
modifier: 814651
product: 814589
product: 814528
reactant: 814444
is: http://identifiers.org/ec-code/1.1.1.2
fast: false
reversible: false
reactant: 814492
modifier: 814675
reactant: 814432
reactant: 814420
product: 814627
modifier: 814663
is: ENSCAFG00000024828.1
reactant: 814480
product: 814577
is: http://identifiers.org/ec-code/1.1.1.21
reactant: 814468

814601
type: SpeciesReference
stoichiometry: 1.0
species: 750902

814564
type: SpeciesReference
stoichiometry: 1.0
species: 750369

814504
type: SpeciesReference
stoichiometry: 6.0
species: 741259

814614
type: SpeciesReference
stoichiometry: 1.0
species: 730196

730196
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Acetol_C3H6O2

814516
type: SpeciesReference
stoichiometry: 6.0
species: 747173

814456
type: SpeciesReference
stoichiometry: 1.0
species: 741151

814552
type: SpeciesReference
stoichiometry: 1.0
species: 726428

814540
type: SpeciesReference
stoichiometry: 1.0
species: 729955

729955
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Arabinitol_C5H12O5

814639
type: SpeciesReference
stoichiometry: 1.0
species: 747173

814589
type: SpeciesReference
stoichiometry: 1.0
species: 744676

814528
type: SpeciesReference
stoichiometry: 1.0
species: 726440

814444
type: SpeciesReference
stoichiometry: 1.0
species: 732056

732056
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Arabinose_C5H10O5

814492
type: SpeciesReference
stoichiometry: 1.0
species: 730196

814432
type: SpeciesReference
stoichiometry: 1.0
species: 747099

814420
type: SpeciesReference
stoichiometry: 3.0
species: 746750

814627
type: SpeciesReference
stoichiometry: 2.0
species: 741259

814480
type: SpeciesReference
stoichiometry: 1.0
species: 744676

814577
type: SpeciesReference
stoichiometry: 6.0
species: 747099

814468
type: SpeciesReference
stoichiometry: 1.0
species: 739815

035517
type: Reaction
is: ENSCAFG00000010388.2
reactant: 800967
product: 800992
reactant: 800943
fast: false
product: 801028
is: http://identifiers.org/ec-code/6.3.5.1
reactant: 800980
reactant: 800955
product: 801040
notes: R_NADS2 subsystem: NAD Metabolism R_NADS2 equation: [c] : atp + dnad + gln-L + h2o --> amp + glu-L + h + nad + ppi
reversible: false
product: 801016
product: 801004
name: NAD synthase (glutamine-hydrolysing)

800967
type: SpeciesReference
stoichiometry: 1.0
species: 741151

800992
type: SpeciesReference
stoichiometry: 1.0
species: 746978

800943
type: SpeciesReference
stoichiometry: 1.0
species: 739926

801028
type: SpeciesReference
stoichiometry: 1.0
species: 741259

800980
type: SpeciesReference
stoichiometry: 1.0
species: 736777

800955
type: SpeciesReference
stoichiometry: 1.0
species: 732441

801040
type: SpeciesReference
stoichiometry: 1.0
species: 749466

801016
type: SpeciesReference
stoichiometry: 1.0
species: 731755

801004
type: SpeciesReference
stoichiometry: 1.0
species: 739987

040839
type: Reaction
reactant: 852664
reversible: true
reactant: 852688
product: 852724
reactant: 852676
product: 852712
notes: R_GK1 subsystem: Nucleotides R_GK1 equation: [c] : atp + gmp <==> adp + gdp R_DGK1 subsystem: Nucleotides R_DGK1 equation: [c] : atp + dgmp <==> adp + dgdp
is: ENSCAFG00000001174.2
is: http://identifiers.org/ec-code/2.7.4.8
product: 852700
fast: false

852664
type: SpeciesReference
stoichiometry: 1.0
species: 735974

735974
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dGMP_C10H12N5O7P

852688
type: SpeciesReference
stoichiometry: 2.0
species: 732441

852724
type: SpeciesReference
stoichiometry: 1.0
species: 735938

735938
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dGDP_C10H12N5O10P2

852676
type: SpeciesReference
stoichiometry: 1.0
species: 740530

852712
type: SpeciesReference
stoichiometry: 2.0
species: 730922

852700
type: SpeciesReference
stoichiometry: 1.0
species: 739656

035660
type: Reaction
product: 802181
reactant: 802157
is: ENSCAFG00000001946.2
notes: R_GALT subsystem: Galactose metabolism R_GALT equation: [c] : gal1p + h + utp <==> ppi + udpgal R_UGLT subsystem: Galactose metabolism R_UGLT equation: [c] : gal1p + udpg <==> g1p + udpgal
product: 802193
reactant: 802133
reversible: true
is: http://identifiers.org/ec-code/2.7.7.12
reactant: 802145
fast: false
product: 802169
is: http://identifiers.org/ec-code/2.7.7.10
reactant: 802121

802181
type: SpeciesReference
stoichiometry: 1.0
species: 738918

802157
type: SpeciesReference
stoichiometry: 1.0
species: 753639

802193
type: SpeciesReference
stoichiometry: 1.0
species: 749466

802133
type: SpeciesReference
stoichiometry: 2.0
species: 739111

739111
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: alpha-D-Galactose 1-phosphate_C6H11O9P

802145
type: SpeciesReference
stoichiometry: 1.0
species: 741259

802169
type: SpeciesReference
stoichiometry: 2.0
species: 753302

802121
type: SpeciesReference
stoichiometry: 1.0
species: 753266

031439
type: Reaction
is: ENSCAFG00000014308.2
name: _5-aminolevulinate synthase
is: ENSCAFG00000009881.2
reactant: 763500
notes: R_ALASm subsystem: Glycine, Serine, and Threonine Metabolism R_ALASm equation: [m] : gly + h + succoa --> 5aop + co2 + coa
product: 763548
reactant: 763512
product: 763536
product: 763524
reversible: false
is: http://identifiers.org/ec-code/2.3.1.37
fast: false
reactant: 763488

763500
type: SpeciesReference
stoichiometry: 1.0
species: 740205

763548
type: SpeciesReference
stoichiometry: 1.0
species: 734005

763512
type: SpeciesReference
stoichiometry: 1.0
species: 741308

763536
type: SpeciesReference
stoichiometry: 1.0
species: 734091

763524
type: SpeciesReference
stoichiometry: 1.0
species: 728535

728535
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _5-Amino-4-oxopentanoate_C5H9NO3

763488
type: SpeciesReference
stoichiometry: 1.0
species: 751687

728245
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _4-Methylzymosterol intermediate 1_C29H46O3

033402
type: Reaction
notes: R_LYSMTF3n subsystem: Lysine Metabolism R_LYSMTF3n equation: [n] : Ndmelys + amet --> Ntmelys + ahcys R_LYSMTF1n subsystem: Lysine Metabolism R_LYSMTF1n equation: [n] : amet + peplys --> Nmelys + ahcys R_LYSMTF2n subsystem: Lysine Metabolism R_LYSMTF2n equation: [n] : Nmelys + amet --> Ndmelys + ahcys R_UREAt subsystem: Transport, Extracellular R_UREAt equation: urea[e] <==> urea[c]
reactant: 781084
modifier: 781156
is: http://identifiers.org/ec-code/2.1.1.43
is: ENSCAFG00000017672.2
product: 781096
reactant: 781060
fast: false
product: 781120
reactant: 781072
product: 781132
reactant: 781048
product: 781108
modifier: 781144
reversible: false

781084
type: SpeciesReference
stoichiometry: 3.0
species: 731718

731718
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: S-Adenosyl-L-methionine_C15H23N6O5S

781096
type: SpeciesReference
stoichiometry: 1.0
species: 729416

781060
type: SpeciesReference
stoichiometry: 1.0
species: 748934

781120
type: SpeciesReference
stoichiometry: 1.0
species: 729441

729441
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Protein N6,N6,N6-trimethyl-L-lysine_C3H10X

781072
type: SpeciesReference
stoichiometry: 1.0
species: 729429

781132
type: SpeciesReference
stoichiometry: 3.0
species: 731297

731297
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

781048
type: SpeciesReference
stoichiometry: 1.0
species: 729416

781108
type: SpeciesReference
stoichiometry: 1.0
species: 729429

735071
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Cytosine_C4H5N3O

032270
type: Reaction
is: ENSCAFG00000011862.2
notes: R_CMPSASn subsystem: Aminosugar Metabolism R_CMPSASn equation: [n] : acnam + ctp --> cmpacna + ppi R_CMPSAS subsystem: Aminosugar Metabolism R_CMPSAS equation: [c] : acnam + ctp --> cmpacna + ppi
reactant: 771445
is: http://identifiers.org/ec-code/2.7.7.43
product: 771517
product: 771493
fast: false
reactant: 771469
reversible: false
product: 771481
reactant: 771457
reactant: 771433
product: 771505

771445
type: SpeciesReference
stoichiometry: 1.0
species: 730645

730645
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Acetylneuraminate_C11H18NO9

771517
type: SpeciesReference
stoichiometry: 1.0
species: 749466

771493
type: SpeciesReference
stoichiometry: 1.0
species: 749490

771469
type: SpeciesReference
stoichiometry: 1.0
species: 735155

771481
type: SpeciesReference
stoichiometry: 1.0
species: 733921

733921
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: CMP-N-acetylneuraminate_C20H29N4O16P

771457
type: SpeciesReference
stoichiometry: 1.0
species: 730669

771433
type: SpeciesReference
stoichiometry: 1.0
species: 735180

735180
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: CTP_C9H12N3O14P3

771505
type: SpeciesReference
stoichiometry: 1.0
species: 733945

751892
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Thiocyanate_CNS

729585
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: R total 3 position_CO2FULLR3

747270
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Nicotinamide_C6H6N2O

737253
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dUDP_C9H11N2O11P2

031451
type: Reaction
reversible: false
is: http://identifiers.org/ec-code/3.1.1.3
reactant: 763584
product: 763609
fast: false
product: 763597
product: 763621
product: 763646
is: ENSCAFG00000010161.2
reactant: 763572
product: 763634
notes: R_LPS2 subsystem: Triacylglycerol Synthesis R_LPS2 equation: [c] : dag_hs + h2o --> Rtotal + h + mag_hs R_LPS subsystem: Triacylglycerol Synthesis R_LPS equation: [c] : h2o + tag_hs --> Rtotal3 + dag_hs + h
reactant: 763560

763584
type: SpeciesReference
stoichiometry: 2.0
species: 741151

763609
type: SpeciesReference
stoichiometry: 1.0
species: 735409

763597
type: SpeciesReference
stoichiometry: 1.0
species: 745856

763621
type: SpeciesReference
stoichiometry: 1.0
species: 729662

729662
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: R total_CO2FULLR

763646
type: SpeciesReference
stoichiometry: 2.0
species: 741259

763572
type: SpeciesReference
stoichiometry: 1.0
species: 751759

763634
type: SpeciesReference
stoichiometry: 1.0
species: 729585

763560
type: SpeciesReference
stoichiometry: 1.0
species: 735409

035059
type: Reaction
reactant: 795298
fast: false
reactant: 795310
reversible: false
is: http://identifiers.org/ec-code/1.2.4.1
is: ENSCAFG00000007340.2
is: ENSCAFG00000013030.2
product: 795334
is: ENSCAFG00000014016.2
product: 795322
notes: R_PDHm subsystem: Glycolysis/Gluconeogenesis R_PDHm equation: [m] : coa + nad + pyr --> accoa + co2 + nadh
name: pyruvate dehydrogenase
reactant: 795286
product: 795346

795298
type: SpeciesReference
stoichiometry: 1.0
species: 750393

795310
type: SpeciesReference
stoichiometry: 1.0
species: 747002

795334
type: SpeciesReference
stoichiometry: 1.0
species: 730148

795322
type: SpeciesReference
stoichiometry: 1.0
species: 734005

795286
type: SpeciesReference
stoichiometry: 1.0
species: 734091

795346
type: SpeciesReference
stoichiometry: 1.0
species: 747062

753967
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3alpha,7alpha-Dihydroxy-5beta-cholestane_C27H48O2

730512
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: N-Acetyl-L-glutamate_C7H9NO5

036688
type: Reaction
is: ENSCAFG00000020332.2
fast: false
product: 810952
reversible: false
reactant: 810916
notes: R_LCAT1e subsystem: Fatty Acid Metabolism R_LCAT1e equation: [e] : chsterol + pchol_hs --> lpchol_hs + xolest2_hs
name: Lecithin-cholesterol acyltransferase
is: http://identifiers.org/ec-code/2.3.1.43
reactant: 810928
product: 810940

810952
type: SpeciesReference
stoichiometry: 1.0
species: 754087

754087
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: cholesterol ester (from FULLR2)_C27H45FULLR2CO2

810916
type: SpeciesReference
stoichiometry: 1.0
species: 748711

810928
type: SpeciesReference
stoichiometry: 1.0
species: 733568

733568
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Cholesterol_C27H46O

810940
type: SpeciesReference
stoichiometry: 1.0
species: 745351

035925
type: Reaction
product: 803919
reactant: 803882
product: 803944
is: ENSCAFG00000012145.2
product: 803956
product: 803932
reactant: 803907
fast: false
reactant: 803894
notes: R_PMI1346PHn subsystem: Inositol Phosphate Metabolism R_PMI1346PHn equation: [n] : h2o + ppmi1346p --> h + mi13456p + pi R_PMI12346PHn subsystem: Inositol Phosphate Metabolism R_PMI12346PHn equation: [n] : h2o + ppmi12346p --> h + minohp + pi
is: http://identifiers.org/ec-code/3.6.1.52
reversible: false

803919
type: SpeciesReference
stoichiometry: 2.0
species: 741320

803882
type: SpeciesReference
stoichiometry: 2.0
species: 741211

741211
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: H2O_H2O

803944
type: SpeciesReference
stoichiometry: 2.0
species: 749261

749261
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Phosphate_HO4P

803956
type: SpeciesReference
stoichiometry: 1.0
species: 746593

746593
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: myo-Inositol hexakisphosphate_C6H6O24P6

803932
type: SpeciesReference
stoichiometry: 1.0
species: 746400

803907
type: SpeciesReference
stoichiometry: 1.0
species: 749562

749562
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Diphosphoinositol tetrakisphosphate_C6H7O24P6

803894
type: SpeciesReference
stoichiometry: 1.0
species: 749538

749538
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: _5-Diphosphoinositol pentakisphosphate_C6H6O27P7

743829
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 23_C185H296N13O153S7X

036531
type: Reaction
product: 809840
is: ENSCAFG00000015545.2
reactant: 809801
fast: false
reversible: false
product: 809814
reactant: 809762
product: 809853
reactant: 809788
reactant: 809775
is: http://identifiers.org/ec-code/2.1.1.43
product: 809827
is: ENSCAFG00000004696.2
is: ENSCAFG00000004955.2
notes: R_LYSMTF3n subsystem: Lysine Metabolism R_LYSMTF3n equation: [n] : Ndmelys + amet --> Ntmelys + ahcys R_LYSMTF1n subsystem: Lysine Metabolism R_LYSMTF1n equation: [n] : amet + peplys --> Nmelys + ahcys R_LYSMTF2n subsystem: Lysine Metabolism R_LYSMTF2n equation: [n] : Nmelys + amet --> Ndmelys + ahcys
is: ENSCAFG00000016783.2
is: ENSCAFG00000019420.2
is: ENSCAFG00000003703.2
is: ENSCAFG00000004341.2
is: ENSCAFG00000015087.2
is: ENSCAFG00000019390.2
is: ENSCAFG00000007493.2

809840
type: SpeciesReference
stoichiometry: 1.0
species: 729441

809801
type: SpeciesReference
stoichiometry: 3.0
species: 731718

809814
type: SpeciesReference
stoichiometry: 1.0
species: 729416

809762
type: SpeciesReference
stoichiometry: 1.0
species: 729416

809853
type: SpeciesReference
stoichiometry: 3.0
species: 731297

809788
type: SpeciesReference
stoichiometry: 1.0
species: 729429

809775
type: SpeciesReference
stoichiometry: 1.0
species: 748934

809827
type: SpeciesReference
stoichiometry: 1.0
species: 729429

039515
type: Reaction
is: http://identifiers.org/ec-code/2.1.4.1
fast: false
is: ENSCAFG00000013733.2
notes: R_GLYAMDTRc subsystem: Urea cycle/amino group metabolism R_GLYAMDTRc equation: [c] : arg-L + gly <==> gudac + orn
product: 838689
reactant: 838650
reactant: 838663
name: glycine amidinotransferase (c)
reversible: true
product: 838676

838689
type: SpeciesReference
stoichiometry: 1.0
species: 748206

748206
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Ornithine_C5H13N2O2

838650
type: SpeciesReference
stoichiometry: 1.0
species: 740168

838663
type: SpeciesReference
stoichiometry: 1.0
species: 732260

838676
type: SpeciesReference
stoichiometry: 1.0
species: 741042

741042
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Guanidinoacetate_C3H7N3O2

731622
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: hydroxy alkyl chain_C2H5OFULLR

030957
type: Reaction
reactant: 758991
product: 759123
product: 759087
reactant: 759051
product: 759135
product: 759099
reactant: 759075
reactant: 759015
product: 759147
reversible: false
reactant: 759003
reactant: 759027
is: ENSCAFG00000013659.2
product: 759159
product: 759184
product: 759171
reactant: 759063
notes: R_HSD3B3r subsystem: Steroid Metabolism R_HSD3B3r equation: [r] : eandrstrn + h + nadph --> andrstandn + h2o + nadp R_HSD3B2r subsystem: Steroid Metabolism R_HSD3B2r equation: [r] : eandrstrn + h + nadh --> andrstandn + h2o + nad R_HSD3B11r subsystem: Steroid Metabolism R_HSD3B11r equation: [r] : nad + prgnlone --> h + nadh + prgstrn R_HSD3B12r subsystem: Steroid Metabolism R_HSD3B12r equation: [r] : dhea + nad --> andrstndn + h + nadh R_HSD3B13r subsystem: Steroid Metabolism R_HSD3B13r equation: [r] : 17ahprgnlone + nad --> 17ahprgstrn + h + nadh
reactant: 759039
product: 759111
fast: false

758991
type: SpeciesReference
stoichiometry: 1.0
species: 749695

759123
type: SpeciesReference
stoichiometry: 1.0
species: 731852

759087
type: SpeciesReference
stoichiometry: 2.0
species: 741223

759051
type: SpeciesReference
stoichiometry: 2.0
species: 741332

759135
type: SpeciesReference
stoichiometry: 1.0
species: 747148

759099
type: SpeciesReference
stoichiometry: 2.0
species: 731840

731840
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: androstanedione_C19H28O2

759075
type: SpeciesReference
stoichiometry: 2.0
species: 737460

759015
type: SpeciesReference
stoichiometry: 1.0
species: 726536

759147
type: SpeciesReference
stoichiometry: 1.0
species: 747026

759003
type: SpeciesReference
stoichiometry: 1.0
species: 747209

759027
type: SpeciesReference
stoichiometry: 3.0
species: 747026

759159
type: SpeciesReference
stoichiometry: 3.0
species: 741332

759184
type: SpeciesReference
stoichiometry: 1.0
species: 726560

759171
type: SpeciesReference
stoichiometry: 3.0
species: 747074

759063
type: SpeciesReference
stoichiometry: 1.0
species: 747074

759039
type: SpeciesReference
stoichiometry: 1.0
species: 736279

759111
type: SpeciesReference
stoichiometry: 1.0
species: 749743

040657
type: Reaction
name: xylulose reductase
reversible: true
is: http://identifiers.org/ec-code/1.1.1.10
product: 850863
reactant: 850827
reactant: 850815
product: 850851
is: ENSCAFG00000005927.2
reactant: 850839
notes: R_XYLUR subsystem: Pentose and Glucuronate Interconversions R_XYLUR equation: [c] : h + nadph + xylu-L <==> nadp + xylt
fast: false

850863
type: SpeciesReference
stoichiometry: 1.0
species: 754293

754293
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Xylitol_C5H12O5

850827
type: SpeciesReference
stoichiometry: 1.0
species: 741259

850815
type: SpeciesReference
stoichiometry: 1.0
species: 754318

754318
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Xylulose_C5H10O5

850851
type: SpeciesReference
stoichiometry: 1.0
species: 747099

850839
type: SpeciesReference
stoichiometry: 1.0
species: 747173

750635
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Retinoate_C20H27O2

744072
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 8_C115H186N8O88S2X

750769
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: de-Fuc form of PA6_C84H135N6O61X

729714
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: R total Coenzyme A_CO2FULLRC21H31N7O15P3S

035311
type: Reaction
is: ENSCAFG00000000249.1
is: ENSCAFG00000016574.2
is: ENSCAFG00000013718.2
reactant: 799485
name: phosphatidylinositol 4-phosphate 5-kinase
reactant: 799497
reversible: false
is: ENSCAFG00000004186.2
product: 799509
is: ENSCAFG00000013684.2
product: 799533
notes: R_PI4P5K subsystem: Glycerophospholipid Metabolism R_PI4P5K equation: [c] : atp + pail4p_hs --> adp + h + pail45p_hs
is: http://identifiers.org/ec-code/2.7.1.68
product: 799521
fast: false

799485
type: SpeciesReference
stoichiometry: 1.0
species: 732441

799497
type: SpeciesReference
stoichiometry: 1.0
species: 748531

799509
type: SpeciesReference
stoichiometry: 1.0
species: 748507

799533
type: SpeciesReference
stoichiometry: 1.0
species: 741259

799521
type: SpeciesReference
stoichiometry: 1.0
species: 730922

731078
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: adrenic acid_C22H35O2

744253
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 2_C39H63N3O28X

730826
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Adenine_C5H5N5

747478
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: NMN_C11H14N2O8P

736789
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Deamino-NAD+_C21H24N6O15P2

036398
type: Reaction
name: deoxyguanosine kinase
reactant: 808854
notes: R_DGNSKm subsystem: Nucleotides R_DGNSKm equation: [m] : atp + dgsn --> adp + dgmp + h
reversible: false
fast: false
is: http://identifiers.org/ec-code/2.7.1.113
product: 808878
product: 808890
reactant: 808842
is: ENSCAFG00000008747.2
product: 808866

808854
type: SpeciesReference
stoichiometry: 1.0
species: 732465

808878
type: SpeciesReference
stoichiometry: 1.0
species: 735999

808890
type: SpeciesReference
stoichiometry: 1.0
species: 741308

808842
type: SpeciesReference
stoichiometry: 1.0
species: 736049

736049
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Deoxyguanosine_C10H13N5O4

808866
type: SpeciesReference
stoichiometry: 1.0
species: 730946

746038
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Mannose 1-phosphate_C6H11O9P

037726
type: Reaction
notes: R_HBZOPT10m subsystem: Ubiquinone Biosynthesis R_HBZOPT10m equation: [m] : 4hbz + decdp --> 3dphb + ppi
product: 822249
reactant: 822225
reversible: false
is: ENSCAFG00000009090.2
product: 822261
reactant: 822237
name: Hydroxybenzoate Decaprenyltransferase
fast: false

822249
type: SpeciesReference
stoichiometry: 1.0
species: 727311

727311
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3-Decaprenyl-4-hydroxybenzoate_C57H85O3

822225
type: SpeciesReference
stoichiometry: 1.0
species: 735889

735889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: all trans Decaprenyl diphosphate_C50H81O7P2

822261
type: SpeciesReference
stoichiometry: 1.0
species: 749478

822237
type: SpeciesReference
stoichiometry: 1.0
species: 728088

735841
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Dodecanoyl-CoA (n-C12:0CoA)_C33H54N7O17P3S

741693
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Hexacosanoyl-CoA (n-C26:0CoA)_C47H82N7O17P3S

738365
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Formate_CH1O2

742988
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Isopentenyl diphosphate_C5H9O7P2

744217
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked)_C81H129N6O67S3X

751276
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Sphinganine 1-phosphate_C18H39NO5P

738450
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Farnesyl diphosphate_C15H25O7P2

745097
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: linoelaidyl coenzyme A_C39H62N7O17P3S

032655
type: Reaction
is: ENSCAFG00000020040.2
reactant: 774785
reversible: false
fast: false
name: glycogen debranching enzyme
is: http://identifiers.org/ec-code/3.2.1.33
notes: R_GLDBRAN subsystem: Starch and Sucrose Metabolism R_GLDBRAN equation: [c] : dxtrn + h2o --> glc-D + glygn3
reactant: 774797
product: 774821
product: 774809

774785
type: SpeciesReference
stoichiometry: 1.0
species: 737399

774797
type: SpeciesReference
stoichiometry: 1.0
species: 741151

774821
type: SpeciesReference
stoichiometry: 1.0
species: 739815

774809
type: SpeciesReference
stoichiometry: 1.0
species: 740421

034228
type: Reaction
product: 788048
reactant: 788036
notes: R_MACACI subsystem: Tyrosine metabolism R_MACACI equation: [c] : 4mlacac --> 4fumacac
is: ENSCAFG00000001923.2
is: http://identifiers.org/ec-code/5.2.1.2
fast: false
reversible: false
name: maleylacetoacetate isomerase

788048
type: SpeciesReference
stoichiometry: 1.0
species: 728052

728052
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Fumarylacetoacetate_C8H6O6

788036
type: SpeciesReference
stoichiometry: 1.0
species: 728185

033766
type: Reaction
is: http://identifiers.org/ec-code/2.4.1.17
name: UDP-glucuronosyltransferase 1-10 precursor, microsomal
product: 783704
reversible: false
is: ENSCAFG00000002831.2
is: ENSCAFG00000025101.1
reactant: 783668
fast: false
is: ENSCAFG00000002836.2
notes: R_UGT1A3r subsystem: Steroid Metabolism R_UGT1A3r equation: [r] : andrstrn + udpglcur --> andrstrnglc + udp
is: ENSCAFG00000024705.1
is: ENSCAFG00000024836.1
is: ENSCAFG00000025306.1
is: ENSCAFG00000014300.2
product: 783692
is: ENSCAFG00000014306.2
is: ENSCAFG00000025592.1
is: ENSCAFG00000002857.2
reactant: 783680

783704
type: SpeciesReference
stoichiometry: 1.0
species: 753206

783668
type: SpeciesReference
stoichiometry: 1.0
species: 753350

783692
type: SpeciesReference
stoichiometry: 1.0
species: 731900

731900
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: androsterone glucuronide_C25H38O8

783680
type: SpeciesReference
stoichiometry: 1.0
species: 731864

744572
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: de-Fuc, reducing GlcNAc removed, de-Sia form of PA6 (w/o peptide linkage)_C54H91N3O41

729054
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: hexaglutamyl folate (THF)_C44H51N12O21

033040
type: Reaction
reactant: 778227
reactant: 778203
notes: R_P4502D6 subsystem: CYP Metabolism R_P4502D6 equation: [c] : debrisoquine + h + nadph + o2 --> 4hdebrisoquine + h2o + nadp
is: ENSCAFG00000000980.2
product: 778239
reactant: 778215
product: 778264
product: 778252
name: cytochrome P450 2D6
reversible: false
fast: false
reactant: 778191

778227
type: SpeciesReference
stoichiometry: 1.0
species: 747173

778203
type: SpeciesReference
stoichiometry: 1.0
species: 747698

778239
type: SpeciesReference
stoichiometry: 1.0
species: 747099

778215
type: SpeciesReference
stoichiometry: 1.0
species: 741259

778264
type: SpeciesReference
stoichiometry: 1.0
species: 741151

778252
type: SpeciesReference
stoichiometry: 1.0
species: 728101

728101
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4 hydroxy debrisoquine_C10H14N3O

778191
type: SpeciesReference
stoichiometry: 1.0
species: 735865

737931
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Ethanolamine phosphate_C2H7NO4P

739365
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: galactocerebroside (homo sapiens)_C24H46NO7FULLRCO

737103
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dTDP_C10H13N2O11P2

031114
type: Reaction
product: 760647
is: ENSCAFG00000009385.2
reactant: 760611
fast: false
product: 760683
reactant: 760623
reversible: false
product: 760671
product: 760659
reactant: 760599
reactant: 760635
notes: R_S6T3g subsystem: Keratan sulfate biosynthesis R_S6T3g equation: [g] : ksii_core2_pre10 + paps --> h + ksii_core2 + pap R_S6T18g subsystem: Keratan sulfate biosynthesis R_S6T18g equation: [g] : ksii_core4_pre10 + paps --> h + ksii_core4 + pap R_S6T15g subsystem: Keratan sulfate biosynthesis R_S6T15g equation: [g] : ksi_pre36 + paps --> h + ksi + pap
product: 760695

760647
type: SpeciesReference
stoichiometry: 1.0
species: 743636

760611
type: SpeciesReference
stoichiometry: 1.0
species: 744000

760683
type: SpeciesReference
stoichiometry: 1.0
species: 744399

760623
type: SpeciesReference
stoichiometry: 3.0
species: 748687

760671
type: SpeciesReference
stoichiometry: 1.0
species: 744205

760659
type: SpeciesReference
stoichiometry: 3.0
species: 748663

760599
type: SpeciesReference
stoichiometry: 1.0
species: 744423

760635
type: SpeciesReference
stoichiometry: 1.0
species: 744229

760695
type: SpeciesReference
stoichiometry: 3.0
species: 741283

741935
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: heptadecanoyl coa_C38H64N7O17P3S

740265
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Glycerol 3-phosphate_C3H7O6P

033876
type: Reaction
product: 784671
reactant: 784635
reactant: 784599
notes: R_PMI1346PHn subsystem: Inositol Phosphate Metabolism R_PMI1346PHn equation: [n] : h2o + ppmi1346p --> h + mi13456p + pi R_PMI1346PH subsystem: Inositol Phosphate Metabolism R_PMI1346PH equation: [c] : h2o + ppmi1346p --> h + mi13456p + pi R_PMI12346PHn subsystem: Inositol Phosphate Metabolism R_PMI12346PHn equation: [n] : h2o + ppmi12346p --> h + minohp + pi R_PMI12346PH subsystem: Inositol Phosphate Metabolism R_PMI12346PH equation: [c] : h2o + ppmi12346p --> h + minohp + pi
is: ENSCAFG00000011226.2
product: 784731
product: 784719
product: 784707
product: 784743
reactant: 784611
fast: false
is: http://identifiers.org/ec-code/3.6.1.52
product: 784659
reactant: 784587
reactant: 784647
reactant: 784623
product: 784683
product: 784695
reversible: false

784671
type: SpeciesReference
stoichiometry: 1.0
species: 746581

746581
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: myo-Inositol hexakisphosphate_C6H6O24P6

784635
type: SpeciesReference
stoichiometry: 1.0
species: 749538

784599
type: SpeciesReference
stoichiometry: 1.0
species: 749550

749550
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Diphosphoinositol tetrakisphosphate_C6H7O24P6

784731
type: SpeciesReference
stoichiometry: 2.0
species: 749261

784719
type: SpeciesReference
stoichiometry: 2.0
species: 741259

784707
type: SpeciesReference
stoichiometry: 1.0
species: 746388

784743
type: SpeciesReference
stoichiometry: 1.0
species: 746593

784611
type: SpeciesReference
stoichiometry: 2.0
species: 741151

784659
type: SpeciesReference
stoichiometry: 2.0
species: 749200

784587
type: SpeciesReference
stoichiometry: 1.0
species: 749526

749526
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Diphosphoinositol pentakisphosphate_C6H6O27P7

784647
type: SpeciesReference
stoichiometry: 1.0
species: 749562

784623
type: SpeciesReference
stoichiometry: 2.0
species: 741211

784683
type: SpeciesReference
stoichiometry: 2.0
species: 741320

784695
type: SpeciesReference
stoichiometry: 1.0
species: 746400

753822
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: omega hydroxy dodecanoate (n-C12:0)_C12H23O3

031981
type: Reaction
is: ENSCAFG00000000211.1
reactant: 768806
product: 768831
is: ENSCAFG00000012522.2
name: adentylate kinase (GTP)
reversible: true
product: 768818
is: ENSCAFG00000015156.2
notes: R_ADK3m subsystem: Nucleotides R_ADK3m equation: [m] : amp + gtp <==> adp + gdp
is: ENSCAFG00000002083.2
is: ENSCAFG00000013746.2
reactant: 768794
fast: false

768806
type: SpeciesReference
stoichiometry: 1.0
species: 731803

768831
type: SpeciesReference
stoichiometry: 1.0
species: 739692

768818
type: SpeciesReference
stoichiometry: 1.0
species: 730946

768794
type: SpeciesReference
stoichiometry: 1.0
species: 740994

728872
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: pentaglutamyl folate (THF)_C39H45N11O18

039911
type: Reaction
product: 841917
reactant: 841905
notes: R_ACGAM2E subsystem: Aminosugar Metabolism R_ACGAM2E equation: [c] : acgam <==> acmana
is: ENSCAFG00000019419.2
is: http://identifiers.org/ec-code/5.1.3.8
fast: false
reversible: true
name: N-acetylglucosamine 2-epimerase

841917
type: SpeciesReference
stoichiometry: 1.0
species: 730573

730573
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Acetyl-D-mannosamine_C8H15NO6

841905
type: SpeciesReference
stoichiometry: 1.0
species: 730403

036917
type: Reaction
is: ENSCAFG00000023408.1
product: 813084
is: ENSCAFG00000006545.2
reversible: true
fast: false
reactant: 813060
product: 813096
name: phosphate transporter, mitochondrial
reactant: 813072
notes: R_PIt2m subsystem: Transport, Mitochondrial R_PIt2m equation: h[c] + pi[c] <==> h[m] + pi[m]

813084
type: SpeciesReference
stoichiometry: 1.0
species: 749249

813060
type: SpeciesReference
stoichiometry: 1.0
species: 749200

813096
type: SpeciesReference
stoichiometry: 1.0
species: 741308

813072
type: SpeciesReference
stoichiometry: 1.0
species: 741259

034046
type: Reaction
notes: R_PPCOAOm subsystem: Propanoate Metabolism R_PPCOAOm equation: [m] : fad + ppcoa --> fadh2 + prpncoa R_ACOAD1fm subsystem: Butanoate Metabolism R_ACOAD1fm equation: [m] : btcoa + fad --> b2coa + fadh2
product: 785801
product: 785789
reactant: 785777
is: ENSCAFG00000008627.2
is: ENSCAFG00000023835.1
reactant: 785765
is: ENSCAFG00000006362.2
reversible: false
is: http://identifiers.org/ec-code/1.3.99.2
product: 785814
fast: false
is: http://identifiers.org/ec-code/1.3.99.3
is: ENSCAFG00000004350.2
reactant: 785753

785801
type: SpeciesReference
stoichiometry: 1.0
species: 750104

785789
type: SpeciesReference
stoichiometry: 2.0
species: 738087

785777
type: SpeciesReference
stoichiometry: 2.0
species: 738039

785765
type: SpeciesReference
stoichiometry: 1.0
species: 749442

749442
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Propanoyl-CoA_C24H36N7O17P3S

785814
type: SpeciesReference
stoichiometry: 1.0
species: 732513

785753
type: SpeciesReference
stoichiometry: 1.0
species: 732805

738522
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: III3Fuc-nLc6Cer_C64H112N3O36FULLRCO

752938
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Thiosulfate_O3S2

732732
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Biocytin_C16H28N4O4S

034613
type: Reaction
product: 792052
notes: R_PETOHMm_hs subsystem: Glycerophospholipid Metabolism R_PETOHMm_hs equation: [m] : (3) amet + pe_hs --> (3) ahcys + (3) h + pchol_hs R_PETOHMr_hs subsystem: Glycerophospholipid Metabolism R_PETOHMr_hs equation: [r] : (3) amet + pe_hs --> (3) ahcys + (3) h + pchol_hs
reactant: 791955
fast: false
reactant: 791979
reactant: 791967
product: 792004
reactant: 791943
product: 792028
reversible: false
product: 792040
product: 791991
product: 792016
is: http://identifiers.org/ec-code/2.1.1.17
is: ENSCAFG00000018444.2

792052
type: SpeciesReference
stoichiometry: 1.0
species: 748747

748747
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

791955
type: SpeciesReference
stoichiometry: 3.0
species: 731706

791979
type: SpeciesReference
stoichiometry: 3.0
species: 731731

731731
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: S-Adenosyl-L-methionine_C15H23N6O5S

791967
type: SpeciesReference
stoichiometry: 1.0
species: 748886

792004
type: SpeciesReference
stoichiometry: 3.0
species: 731309

731309
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

791943
type: SpeciesReference
stoichiometry: 1.0
species: 748873

792028
type: SpeciesReference
stoichiometry: 3.0
species: 741332

792040
type: SpeciesReference
stoichiometry: 3.0
species: 741308

791991
type: SpeciesReference
stoichiometry: 3.0
species: 731285

792016
type: SpeciesReference
stoichiometry: 1.0
species: 748735

748735
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

031523
type: Reaction
product: 764118
reversible: false
product: 764178
product: 764154
is: http://identifiers.org/ec-code/2.4.99.8
reactant: 764070
reactant: 764022
product: 764094
product: 764130
reactant: 764034
reactant: 764082
notes: R_ST8SIA53g subsystem: Sphingolipid Metabolism R_ST8SIA53g equation: [g] : cmpacna + gd1a_hs --> cmp + gt1a_hs + h R_ST8SIA51g subsystem: Sphingolipid Metabolism R_ST8SIA51g equation: [g] : cmpacna + gd3_hs --> cmp + gt3_hs + h R_ST8SIA56g subsystem: Blood Group Biosynthesis R_ST8SIA56g equation: [g] : acngal14acglcgalgluside_hs + cmpacna --> acnacngal14acglcgalgluside_hs + cmp + h R_ST8SIA52g subsystem: Sphingolipid Metabolism R_ST8SIA52g equation: [g] : cmpacna + gt1b_hs --> cmp + gq1b_hs + h R_ST8SIA54g subsystem: Sphingolipid Metabolism R_ST8SIA54g equation: [g] : cmpacna + gm1b_hs --> cmp + gd1c_hs + h R_ST8SIA55g subsystem: Sphingolipid Metabolism R_ST8SIA55g equation: [g] : cmpacna + gq1c_hs --> cmp + gp1calpha_hs + h
product: 764106
is: ENSCAFG00000017615.2
product: 764166
product: 764142
reactant: 764058
fast: false
reactant: 764046
reactant: 764009

764118
type: SpeciesReference
stoichiometry: 1.0
species: 730621

730621
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: _3',8'-LD1_C66H111N4O38FULLRCO

764178
type: SpeciesReference
stoichiometry: 1.0
species: 740874

740874
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GT3 (homo sapiens)_C63H104N4O36FULLRCO

764154
type: SpeciesReference
stoichiometry: 1.0
species: 739595

739595
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GD1c (homo sapiens)_C66H111N4O38FULLRCO

764070
type: SpeciesReference
stoichiometry: 1.0
species: 740825

764022
type: SpeciesReference
stoichiometry: 1.0
species: 740481

764094
type: SpeciesReference
stoichiometry: 1.0
species: 740627

740627
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GP1c alpha (homo sapiens)_C99H159N7O62FULLRCO

764130
type: SpeciesReference
stoichiometry: 6.0
species: 741283

764034
type: SpeciesReference
stoichiometry: 6.0
species: 733933

764082
type: SpeciesReference
stoichiometry: 1.0
species: 739631

739631
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GD3 (homo sapiens)_C52H88N3O28FULLRCO

764106
type: SpeciesReference
stoichiometry: 1.0
species: 740799

740799
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GT1a (homo sapiens)_C77H127N5O46FULLRCO

764166
type: SpeciesReference
stoichiometry: 1.0
species: 740687

740687
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GQ1b (homo sapiens)_C88H143N6O54FULLRCO

764142
type: SpeciesReference
stoichiometry: 6.0
species: 733884

764058
type: SpeciesReference
stoichiometry: 1.0
species: 740711

740711
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GQ1c (homo sapiens)_C88H143N6O54FULLRCO

764046
type: SpeciesReference
stoichiometry: 1.0
species: 730693

764009
type: SpeciesReference
stoichiometry: 1.0
species: 739547

736123
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Dihydroxyacetone phosphate_C3H5O6P

739329
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: galactosyl glucosyl ceramide_C30H56NO12FULLRCO

739741
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GDP-L-fucose_C16H23N5O15P2

748995
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphatidylglycerol (homo sapiens)_C6H12O6PFULLRCO2FULLR2CO2

035565
type: Reaction
name: _3-oxoacid CoA-transferase
product: 801330
reversible: true
is: ENSCAFG00000018589.2
reactant: 801305
product: 801318
notes: R_OCOAT1m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OCOAT1m equation: [m] : acac + succoa <==> aacoa + succ
fast: false
reactant: 801293
is: http://identifiers.org/ec-code/2.8.3.5

801330
type: SpeciesReference
stoichiometry: 1.0
species: 751651

801305
type: SpeciesReference
stoichiometry: 1.0
species: 730052

801318
type: SpeciesReference
stoichiometry: 1.0
species: 729919

801293
type: SpeciesReference
stoichiometry: 1.0
species: 751687

034156
type: Reaction
notes: R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h
name: _3',5'-cyclic-nucleotide phosphodiesterase
is: http://identifiers.org/ec-code/3.1.4.17
reversible: false
product: 787542
reactant: 787518
reactant: 787530
product: 787554
is: ENSCAFG00000007908.2
is: ENSCAFG00000012874.2
is: ENSCAFG00000005767.1
fast: false
is: ENSCAFG00000016782.2
is: ENSCAFG00000011104.2
is: ENSCAFG00000018251.2

787542
type: SpeciesReference
stoichiometry: 1.0
species: 740530

787518
type: SpeciesReference
stoichiometry: 1.0
species: 727190

787530
type: SpeciesReference
stoichiometry: 1.0
species: 741151

787554
type: SpeciesReference
stoichiometry: 1.0
species: 741259

726380
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _11-Deoxycorticosterone_C21H30O3

030729
type: Reaction
product: 757404
reactant: 756982
reactant: 757018
reactant: 757188
fast: false
reactant: 757054
reactant: 756970
product: 757368
reactant: 756958
product: 757332
reactant: 757151
product: 757356
reactant: 757030
product: 757320
reactant: 757102
reactant: 757127
is: http://identifiers.org/ec-code/1.3.3.6
product: 757344
reactant: 757090
reactant: 757078
reactant: 756994
reactant: 757006
reactant: 757163
reactant: 757115
reactant: 757066
product: 757284
product: 757272
notes: R_FAOXC2251836x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2251836x equation: [x] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_FAOXC180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC180x equation: [x] : coa + h2o + nad + o2 + stcoa --> accoa + h + h2o2 + nadh + pmtcoa R_FAOXC241181x subsystem: Fatty acid oxidation, peroxisome R_FAOXC241181x equation: [x] : (3) coa + (3) h2o + (3) nad + nrvnccoa + (3) o2 --> (3) accoa + (3) h + (3) h2o2 + (3) nadh + odecoa R_FAOXC2051843x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2051843x equation: [x] : coa + h2o + nad + tmndnccoa --> accoa + h + nadh + strdnccoa R_FAOXC2452253x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2452253x equation: [x] : coa + h2o + nad + o2 + tetpent3coa --> accoa + clpndcoa + h + h2o2 + nadh R_FAOXC2252053x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2252053x equation: [x] : coa + dcsptn1coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + tmndnccoa R_FAOXC183806x subsystem: Fatty acid oxidation, peroxisome R_FAOXC183806x equation: [x] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC200180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC200180x equation: [x] : arachcoa + coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + stcoa R_FAOXC16080x subsystem: Fatty acid oxidation, peroxisome R_FAOXC16080x equation: [x] : (4) coa + (4) h2o + (4) nad + (4) o2 + pmtcoa --> (4) accoa + (4) h + (4) h2o2 + (4) nadh + occoa R_FAOXC2242046x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2242046x equation: [x] : adrncoa + coa + h2o + nad + o2 --> accoa + arachdcoa + h + h2o2 + nadh R_FAOXC246226x subsystem: Fatty acid oxidation, peroxisome R_FAOXC246226x equation: [x] : coa + h2o + nad + o2 + tethex3coa --> accoa + c226coa + h + h2o2 + nadh R_ACOAO7p subsystem: Fatty Acid Metabolism R_ACOAO7p equation: [x] : o2 + pmtcoa --> h2o2 + hdd2coa R_FAOXC18480x subsystem: Fatty acid …
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reactant: 757139
product: 757260
is: ENSCAFG00000004989.2
product: 757248
product: 757236
product: 757200
product: 757392
product: 757224
is: http://identifiers.org/ec-code/1.3.99.3
product: 757380
product: 757212
reactant: 757175
product: 757416
product: 757296
product: 757308
reversible: false

757404
type: SpeciesReference
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species: 741139

756982
type: SpeciesReference
stoichiometry: 1.0
species: 744976

744976
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: lignocericyl coenzyme A_C45H78N7O17P3S

757018
type: SpeciesReference
stoichiometry: 32.0
species: 747038

747038
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

757188
type: SpeciesReference
stoichiometry: 1.0
species: 752109

752109
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: tetracosapentaenoyl coenzyme A, n-6_C45H68N7O17P3S

757054
type: SpeciesReference
stoichiometry: 2.0
species: 735673

756970
type: SpeciesReference
stoichiometry: 1.0
species: 747638

747638
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: nervonyl coenzyme A_C45H76N7O17P3S

757368
type: SpeciesReference
stoichiometry: 1.0
species: 741609

741609
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137

756958
type: SpeciesReference
stoichiometry: 2.0
species: 749322

757332
type: SpeciesReference
stoichiometry: 1.0
species: 751494

751494
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S

757151
type: SpeciesReference
stoichiometry: 1.0
species: 745290

745290
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: gamma-linolenoyl-CoA_C39H60N7O17P3S

757356
type: SpeciesReference
stoichiometry: 1.0
species: 732937

732937
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: cervonyl coenzyme A_C43H62N7O17P3S

757030
type: SpeciesReference
stoichiometry: 1.0
species: 751591

751591
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: stearidonyl coenzyme A_C39H58N7O17P3S

757320
type: SpeciesReference
stoichiometry: 32.0
species: 741344

757102
type: SpeciesReference
stoichiometry: 32.0
species: 734127

757127
type: SpeciesReference
stoichiometry: 1.0
species: 752181

757344
type: SpeciesReference
stoichiometry: 1.0
species: 745290

757090
type: SpeciesReference
stoichiometry: 1.0
species: 752667

752667
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: timnodonyl coenzyme A_C41H60N7O17P3S

757078
type: SpeciesReference
stoichiometry: 1.0
species: 732116

732116
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: arachidyl coenzyme A_C41H70N7O17P3S

756994
type: SpeciesReference
stoichiometry: 32.0
species: 741235

757006
type: SpeciesReference
stoichiometry: 1.0
species: 752037

752037
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: tetracosapentaenoyl coenzyme A, n-3_C45H68N7O17P3S

757163
type: SpeciesReference
stoichiometry: 1.0
species: 731127

757115
type: SpeciesReference
stoichiometry: 1.0
species: 751494

757066
type: SpeciesReference
stoichiometry: 1.0
species: 751989

751989
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: tetracosahexaenoyl coenzyme A_C45H66N7O17P3S

757284
type: SpeciesReference
stoichiometry: 1.0
species: 748109

748109
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Octadecenoyl-CoA (n-C18:1CoA)_C39H64N7O17P3S

757272
type: SpeciesReference
stoichiometry: 32.0
species: 747087

747087
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

757042
type: SpeciesReference
stoichiometry: 22.0
species: 747758

757139
type: SpeciesReference
stoichiometry: 1.0
species: 732937

757260
type: SpeciesReference
stoichiometry: 3.0
species: 747938

747938
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Octanoyl-CoA (n-C8:0CoA)_C29H46N7O17P3S

757248
type: SpeciesReference
stoichiometry: 1.0
species: 735673

757236
type: SpeciesReference
stoichiometry: 1.0
species: 751591

757200
type: SpeciesReference
stoichiometry: 1.0
species: 733810

733810
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: clupanodonyl CoA_C43H64N7O17P3S

757392
type: SpeciesReference
stoichiometry: 1.0
species: 731127

757224
type: SpeciesReference
stoichiometry: 1.0
species: 744976

757380
type: SpeciesReference
stoichiometry: 32.0
species: 730184

757212
type: SpeciesReference
stoichiometry: 1.0
species: 749322

757175
type: SpeciesReference
stoichiometry: 1.0
species: 741705

757416
type: SpeciesReference
stoichiometry: 1.0
species: 732212

732212
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: C20:4-CoA_C41H62N7O17P3S

757296
type: SpeciesReference
stoichiometry: 1.0
species: 732116

757308
type: SpeciesReference
stoichiometry: 2.0
species: 752667

738063
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

039791
type: Reaction
reactant: 841233
is: ENSCAFG00000012811.2
product: 841245
fast: false
name: protoporphyrinogen oxidase, mitochondrial
reactant: 841221
is: http://identifiers.org/ec-code/1.3.3.4
product: 841257
notes: R_PPPGOm subsystem: Heme Biosynthesis R_PPPGOm equation: [m] : (3) o2 + (2) pppg9 --> (6) h2o + (2) ppp9
reversible: false

841233
type: SpeciesReference
stoichiometry: 3.0
species: 747722

841245
type: SpeciesReference
stoichiometry: 6.0
species: 741199

841221
type: SpeciesReference
stoichiometry: 2.0
species: 749598

749598
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Protoporphyrinogen IX_C34H38N4O4

841257
type: SpeciesReference
stoichiometry: 2.0
species: 749574

744940
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: lignoceric acid_C24H47O2

038972
type: Reaction
reactant: 832965
is: ENSCAFG00000009873.2
reversible: false
reactant: 832857
product: 833050
reactant: 832953
product: 833014
product: 833062
is: http://identifiers.org/ec-code/3.2.1.113
product: 833026
reactant: 832905
reactant: 832977
reactant: 832893
product: 833074
product: 833038
reactant: 832869
is: ENSCAFG00000019511.2
product: 832989
reactant: 832929
product: 833001
product: 833086
reactant: 832941
notes: R_MM5bg subsystem: N-Glycan Biosynthesis R_MM5bg equation: [g] : h2o + m5masnB1 --> m4masn + man R_MM7Cbg subsystem: N-Glycan Biosynthesis R_MM7Cbg equation: [g] : h2o + m7masnC --> m6masnC + man R_MM6B2g subsystem: N-Glycan Biosynthesis R_MM6B2g equation: [g] : h2o + m6masnB2 --> m5masnB2 + man R_MM6bg subsystem: N-Glycan Biosynthesis R_MM6bg equation: [g] : h2o + m6masnC --> m5masnC + man R_MM8Ag subsystem: N-Glycan Biosynthesis R_MM8Ag equation: [g] : h2o + m8masn --> m7masnA + man R_MM8Cg subsystem: N-Glycan Biosynthesis R_MM8Cg equation: [g] : h2o + m8masn --> m7masnC + man R_MM7Cag subsystem: N-Glycan Biosynthesis R_MM7Cag equation: [g] : h2o + m7masnA --> m6masnC + man R_MM6B1ag subsystem: N-Glycan Biosynthesis R_MM6B1ag equation: [g] : h2o + m6masnB1 --> m5masnB1 + man R_MM7B2g subsystem: N-Glycan Biosynthesis R_MM7B2g equation: [g] : h2o + m7masnB --> m6masnB2 + man R_MM6B1bg subsystem: N-Glycan Biosynthesis R_MM6B1bg equation: [g] : h2o + m6masnB2 --> m5masnB1 + man R_MM5ag subsystem: N-Glycan Biosynthesis R_MM5ag equation: [g] : h2o + m5masnC --> m4masn + man R_MM5cg subsystem: N-Glycan Biosynthesis R_MM5cg equation: [g] : h2o + m5masnB2 --> m4masn + man R_MM7B1g subsystem: N-Glycan Biosynthesis R_MM7B1g equation: [g] : h2o + m7masnB --> m6masnB1 + man
fast: false
reactant: 832917
product: 833098
reactant: 832881

832965
type: SpeciesReference
stoichiometry: 2.0
species: 745784

832857
type: SpeciesReference
stoichiometry: 2.0
species: 745723

833050
type: SpeciesReference
stoichiometry: 2.0
species: 745675

832953
type: SpeciesReference
stoichiometry: 2.0
species: 745663

833014
type: SpeciesReference
stoichiometry: 1.0
species: 745603

833062
type: SpeciesReference
stoichiometry: 1.0
species: 745711

833026
type: SpeciesReference
stoichiometry: 1.0
species: 745747

832905
type: SpeciesReference
stoichiometry: 13.0
species: 741175

832977
type: SpeciesReference
stoichiometry: 1.0
species: 745579

832893
type: SpeciesReference
stoichiometry: 1.0
species: 745747

833074
type: SpeciesReference
stoichiometry: 1.0
species: 745663

833038
type: SpeciesReference
stoichiometry: 1.0
species: 745651

832869
type: SpeciesReference
stoichiometry: 1.0
species: 745591

832989
type: SpeciesReference
stoichiometry: 3.0
species: 745543

832929
type: SpeciesReference
stoichiometry: 1.0
species: 745675

833001
type: SpeciesReference
stoichiometry: 1.0
species: 745591

833086
type: SpeciesReference
stoichiometry: 13.0
species: 746086

832941
type: SpeciesReference
stoichiometry: 1.0
species: 745711

832917
type: SpeciesReference
stoichiometry: 1.0
species: 745651

833098
type: SpeciesReference
stoichiometry: 2.0
species: 745579

832881
type: SpeciesReference
stoichiometry: 1.0
species: 745603

040441
type: Reaction
product: 847209
reactant: 847196
reactant: 847183
product: 847221
is: ENSCAFG00000017195.2
fast: false
notes: R_TRIODTHYt2 subsystem: Transport, Extracellular R_TRIODTHYt2 equation: triodthy[e] <==> triodthy[c] R_THYOXt2 subsystem: Transport, Extracellular R_THYOXt2 equation: thyox-L[e] <==> thyox-L[c]
reversible: true

847209
type: SpeciesReference
stoichiometry: 1.0
species: 752581

752581
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Thyroxine_C15H11I4NO4

847196
type: SpeciesReference
stoichiometry: 1.0
species: 752803

752803
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Triiodothyronine_C15H12I3NO4

847183
type: SpeciesReference
stoichiometry: 1.0
species: 752593

752593
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Thyroxine_C15H11I4NO4

847221
type: SpeciesReference
stoichiometry: 1.0
species: 752790

729270
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-2-Aminoadipate_C6H10NO4

752752
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Reduced thioredoxin_XH2

730585
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Acetyl-D-mannosamine 6-phosphate_C8H14NO9P

754147
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _7-alpha,25-Dihydroxycholesterol_C27H46O3

040851
type: Reaction
product: 852820
is: ENSCAFG00000016988.2
reversible: false
reactant: 852736
product: 852784
reactant: 852772
product: 852796
is: http://identifiers.org/ec-code/3.2.1.45
notes: R_GBAl subsystem: Sphingolipid Metabolism R_GBAl equation: [l] : gluside_hs + h2o --> crm_hs + glc-D R_GBA subsystem: Sphingolipid Metabolism R_GBA equation: [c] : gluside_hs + h2o --> crm_hs + glc-D
reactant: 852748
product: 852808
reactant: 852760
fast: false

852820
type: SpeciesReference
stoichiometry: 1.0
species: 739815

852736
type: SpeciesReference
stoichiometry: 1.0
species: 740071

740071
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO

852784
type: SpeciesReference
stoichiometry: 1.0
species: 734308

734308
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

852772
type: SpeciesReference
stoichiometry: 1.0
species: 740095

740095
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO

852796
type: SpeciesReference
stoichiometry: 1.0
species: 739852

852748
type: SpeciesReference
stoichiometry: 1.0
species: 741187

852808
type: SpeciesReference
stoichiometry: 1.0
species: 734283

734283
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

852760
type: SpeciesReference
stoichiometry: 1.0
species: 741151

731984
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Apocarboxylase (Lys residue)_C6H13N2OX

040729
type: Reaction
modifier: 851521
reversible: false
is: http://identifiers.org/ec-code/1.1.1.27
product: 851401
modifier: 851485
reactant: 851350
is: http://identifiers.org/ec-code/1.2.3.5
is: ENSCAFG00000009323.2
modifier: 851461
product: 851389
modifier: 851497
reactant: 851376
modifier: 851437
product: 851413
modifier: 851425
notes: R_LDH_L subsystem: Glycolysis/Gluconeogenesis R_LDH_L equation: [c] : lac-L + nad <==> h + nadh + pyr R_MCLOR subsystem: Cysteine Metabolism R_MCLOR equation: [c] : mercplac + nad <==> h + mercppyr + nadh R_2HBO subsystem: Propanoate Metabolism R_2HBO equation: [c] : 2hb + nad <==> 2obut + h + nadh R_GLXO1 subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO1 equation: [c] : glx + h2o + nad --> (2) h + nadh + oxa
fast: false
modifier: 851473
reactant: 851363
modifier: 851509
modifier: 851449

851401
type: SpeciesReference
stoichiometry: 2.0
species: 741259

851350
type: SpeciesReference
stoichiometry: 1.0
species: 746978

851389
type: SpeciesReference
stoichiometry: 1.0
species: 748266

851376
type: SpeciesReference
stoichiometry: 1.0
species: 741151

851413
type: SpeciesReference
stoichiometry: 1.0
species: 747050

851363
type: SpeciesReference
stoichiometry: 1.0
species: 740132

039466
type: Reaction
reversible: false
is: ENSCAFG00000001945.2
product: 838349
product: 838373
is: http://identifiers.org/ec-code/1.14.14.1
name: cytochrome P450 lanosterol 14-alpha-demethylase
fast: false
product: 838361
notes: R_LNS14DMr subsystem: Cholesterol Metabolism R_LNS14DMr equation: [r] : (2) h + lanost + (3) nadph + (3) o2 --> 44mctr + for + (4) h2o + (3) nadp
reactant: 838313
product: 838337
reactant: 838325
reactant: 838289
reactant: 838301

838349
type: SpeciesReference
stoichiometry: 4.0
species: 741223

838373
type: SpeciesReference
stoichiometry: 1.0
species: 727905

727905
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _4,4-dimethylcholesta-8,14,24-trienol_C29H46O

838361
type: SpeciesReference
stoichiometry: 3.0
species: 747148

838313
type: SpeciesReference
stoichiometry: 3.0
species: 747209

838337
type: SpeciesReference
stoichiometry: 1.0
species: 738377

838325
type: SpeciesReference
stoichiometry: 2.0
species: 741332

838289
type: SpeciesReference
stoichiometry: 3.0
species: 747746

838301
type: SpeciesReference
stoichiometry: 1.0
species: 744736

744736
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Lanosterol_C30H50O

746207
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Methanol_CH4O1

037798
type: Reaction
product: 822791
product: 822827
reversible: false
reactant: 822743
is: ENSCAFG00000001937.2
product: 822815
reactant: 822755
reactant: 822731
fast: false
is: ENSCAFG00000013713.2
reactant: 822719
product: 822803
notes: R_GLYKm subsystem: Glycerophospholipid Metabolism R_GLYKm equation: [m] : atp + glyc --> adp + glyc3p + h R_GLYK subsystem: Glycerophospholipid Metabolism R_GLYK equation: [c] : atp + glyc --> adp + glyc3p + h
product: 822779
is: http://identifiers.org/ec-code/2.7.1.30
product: 822767
is: ENSCAFG00000000233.2

822791
type: SpeciesReference
stoichiometry: 1.0
species: 730922

822827
type: SpeciesReference
stoichiometry: 1.0
species: 741308

822743
type: SpeciesReference
stoichiometry: 1.0
species: 732465

822815
type: SpeciesReference
stoichiometry: 1.0
species: 741259

822755
type: SpeciesReference
stoichiometry: 1.0
species: 740313

822731
type: SpeciesReference
stoichiometry: 1.0
species: 740337

822719
type: SpeciesReference
stoichiometry: 1.0
species: 732441

822803
type: SpeciesReference
stoichiometry: 1.0
species: 740265

822779
type: SpeciesReference
stoichiometry: 1.0
species: 730946

822767
type: SpeciesReference
stoichiometry: 1.0
species: 740277

737007
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dopaquinone_C9H9NO4

038646
type: Reaction
reactant: 830596
reactant: 830583
reversible: false
is: http://identifiers.org/ec-code/2.1.2.5
product: 830669
product: 830633
product: 830645
notes: R_GluForTx subsystem: Histidine Metabolism R_GluForTx equation: [c] : forglu + h + thf --> 5forthf + glu-L R_FTCD subsystem: Folate Metabolism R_FTCD equation: [c] : 5forthf + (2) h --> methf + nh4
reactant: 830621
product: 830657
is: http://identifiers.org/ec-code/4.3.1.4
fast: false
reactant: 830609
is: ENSCAFG00000011926.2

830596
type: SpeciesReference
stoichiometry: 1.0
species: 738389

738389
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Formimidoyl-L-glutamate_C6H8N2O4

830583
type: SpeciesReference
stoichiometry: 1.0
species: 752337

830669
type: SpeciesReference
stoichiometry: 1.0
species: 728607

728607
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Formiminotetrahydrofolate_C20H22N8O6

830633
type: SpeciesReference
stoichiometry: 1.0
species: 747294

830645
type: SpeciesReference
stoichiometry: 1.0
species: 746315

830621
type: SpeciesReference
stoichiometry: 3.0
species: 741259

830657
type: SpeciesReference
stoichiometry: 1.0
species: 739987

830609
type: SpeciesReference
stoichiometry: 1.0
species: 728607

740862
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: GT3 (homo sapiens)_C63H104N4O36FULLRCO

739220
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Gal-GlcNAc-Gal globoside (homo sapiens)_C64H112N3O37FULLRCO

739913
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: D-Glucuronate_C6H9O7

751106
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Serine_C3H7NO3

735276
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Cytidine_C9H13N3O5

030825
type: Reaction
product: 758110
notes: R_MDHm subsystem: Citric Acid Cycle R_MDHm equation: [m] : mal-L + nad <==> h + nadh + oaa R_SLDxm subsystem: Cysteine Metabolism R_SLDxm equation: [m] : nad + sl-L <==> 3spyr + h + nadh
is: http://identifiers.org/ec-code/1.1.1.37
product: 758074
reactant: 758062
fast: false
reactant: 758050
is: http://identifiers.org/ec-code/1.1.1.272
product: 758086
reversible: true
reactant: 758037
product: 758098
is: ENSCAFG00000010414.2

758110
type: SpeciesReference
stoichiometry: 2.0
species: 747062

758074
type: SpeciesReference
stoichiometry: 1.0
species: 727856

727856
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3-Sulfopyruvate_C3H2O6S

758062
type: SpeciesReference
stoichiometry: 1.0
species: 745916

758050
type: SpeciesReference
stoichiometry: 2.0
species: 747002

758086
type: SpeciesReference
stoichiometry: 1.0
species: 747842

758037
type: SpeciesReference
stoichiometry: 1.0
species: 751166

751166
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-sulfolactate_C3H4O6S

758098
type: SpeciesReference
stoichiometry: 2.0
species: 741308

035985
type: Reaction
fast: false
product: 805333
reactant: 805189
product: 805261
reactant: 805201
product: 805309
product: 805321
reactant: 805225
notes: R_PCFLOPm subsystem: Transport, Mitochondrial R_PCFLOPm equation: atp[c] + h2o[c] + pchol_hs[m] --> adp[c] + h[c] + pchol_hs[c] + pi[c] R_PSFLIP subsystem: Transport, Extracellular R_PSFLIP equation: atp[c] + h2o[c] + ps_hs[e] --> adp[c] + h[c] + pi[c] + ps_hs[c] R_PEFLIP subsystem: Transport, Extracellular R_PEFLIP equation: atp[c] + h2o[c] + pe_hs[e] --> adp[c] + h[c] + pe_hs[c] + pi[c] R_PSFLIPm subsystem: Transport, Mitochondrial R_PSFLIPm equation: atp[c] + h2o[c] + ps_hs[c] --> adp[c] + h[c] + pi[c] + ps_hs[m] R_PEFLIPm subsystem: Transport, Mitochondrial R_PEFLIPm equation: atp[c] + h2o[c] + pe_hs[c] --> adp[c] + h[c] + pe_hs[m] + pi[c]
is: ENSCAFG00000010085.2
product: 805345
reactant: 805213
product: 805297
reversible: false
reactant: 805177
reactant: 805237
product: 805273
product: 805285
reactant: 805249

805333
type: SpeciesReference
stoichiometry: 5.0
species: 741259

805189
type: SpeciesReference
stoichiometry: 1.0
species: 748847

805261
type: SpeciesReference
stoichiometry: 5.0
species: 749200

805201
type: SpeciesReference
stoichiometry: 1.0
species: 748860

805309
type: SpeciesReference
stoichiometry: 5.0
species: 730922

805321
type: SpeciesReference
stoichiometry: 1.0
species: 750165

805225
type: SpeciesReference
stoichiometry: 1.0
species: 750153

805345
type: SpeciesReference
stoichiometry: 1.0
species: 750141

805213
type: SpeciesReference
stoichiometry: 5.0
species: 741151

805297
type: SpeciesReference
stoichiometry: 1.0
species: 748847

805177
type: SpeciesReference
stoichiometry: 5.0
species: 732441

805237
type: SpeciesReference
stoichiometry: 1.0
species: 748735

805273
type: SpeciesReference
stoichiometry: 1.0
species: 748699

805285
type: SpeciesReference
stoichiometry: 1.0
species: 748873

805249
type: SpeciesReference
stoichiometry: 1.0
species: 750141

031608
type: Reaction
is: ENSCAFG00000017655.2
fast: false
product: 764685
is: ENSCAFG00000016959.2
reactant: 764661
is: ENSCAFG00000010413.2
product: 764673
reversible: false
notes: R_PYK subsystem: Glycolysis/Gluconeogenesis R_PYK equation: [c] : adp + h + pep --> atp + pyr
reactant: 764637
is: http://identifiers.org/ec-code/2.7.1.40
reactant: 764649
name: pyruvate kinase

764685
type: SpeciesReference
stoichiometry: 1.0
species: 732441

764661
type: SpeciesReference
stoichiometry: 1.0
species: 741259

764673
type: SpeciesReference
stoichiometry: 1.0
species: 750369

764637
type: SpeciesReference
stoichiometry: 1.0
species: 730922

764649
type: SpeciesReference
stoichiometry: 1.0
species: 748910

040284
type: Reaction
is: ENSCAFG00000011944.1
fast: false
is: ENSCAFG00000011947.2
reversible: true
is: http://identifiers.org/ec-code/1.11.1.9
reactant: 845367
reactant: 845355
notes: R_GTHPe subsystem: Glutathione Metabolism R_GTHPe equation: [e] : (2) gthrd + h2o2 <==> gthox + (2) h2o
product: 845379
name: glutathione peroxidase (e)
product: 845391

845367
type: SpeciesReference
stoichiometry: 1.0
species: 741090

845355
type: SpeciesReference
stoichiometry: 2.0
species: 740934

740934
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Reduced glutathione_C10H16N3O6S

845379
type: SpeciesReference
stoichiometry: 1.0
species: 740898

845391
type: SpeciesReference
stoichiometry: 2.0
species: 741163

041009
type: Reaction
reactant: 853807
is: ENSCAFG00000018788.2
product: 853844
fast: false
is: ENSCAFG00000015085.2
product: 853832
is: ENSCAFG00000011425.2
product: 853820
is: ENSCAFG00000023246.1
is: ENSCAFG00000023233.1
reactant: 853795
is: http://identifiers.org/ec-code/3.1.1.4
notes: R_PLA2_2e subsystem: Glycerophospholipid Metabolism R_PLA2_2e equation: [e] : h2o + pchol_hs --> Rtotal2 + h + lpchol_hs
is: ENSCAFG00000010263.2
is: ENSCAFG00000015097.2
reversible: false
name: phospholipase A2

853807
type: SpeciesReference
stoichiometry: 1.0
species: 741163

853844
type: SpeciesReference
stoichiometry: 1.0
species: 729525

729525
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: R total 2 position_CO2FULLR2

853832
type: SpeciesReference
stoichiometry: 1.0
species: 741271

853820
type: SpeciesReference
stoichiometry: 1.0
species: 745351

853795
type: SpeciesReference
stoichiometry: 1.0
species: 748711

039575
type: Reaction
reactant: 839065
fast: false
reactant: 839077
reversible: false
product: 839113
product: 839089
reactant: 839041
product: 839101
reactant: 839053
is: ENSCAFG00000010814.2
notes: R_CH25H subsystem: Bile Acid Biosynthesis R_CH25H equation: [r] : chsterol + h + nadph + o2 --> h2o + nadp + xol25oh
name: cholesterol 25-hydroxylase

839065
type: SpeciesReference
stoichiometry: 1.0
species: 747209

839077
type: SpeciesReference
stoichiometry: 1.0
species: 741332

839113
type: SpeciesReference
stoichiometry: 1.0
species: 747148

839089
type: SpeciesReference
stoichiometry: 1.0
species: 741223

839041
type: SpeciesReference
stoichiometry: 1.0
species: 747746

839101
type: SpeciesReference
stoichiometry: 1.0
species: 753918

839053
type: SpeciesReference
stoichiometry: 1.0
species: 733618

037315
type: Reaction
product: 816885
reactant: 816861
is: ENSCAFG00000015340.2
reactant: 816849
is: http://identifiers.org/ec-code/2.7.1.20
name: adenosine kinase
product: 816897
reversible: false
product: 816873
notes: R_ADNK1 subsystem: Nucleotides R_ADNK1 equation: [c] : adn + atp --> adp + amp + h
fast: false

816885
type: SpeciesReference
stoichiometry: 1.0
species: 731755

816861
type: SpeciesReference
stoichiometry: 1.0
species: 730862

816849
type: SpeciesReference
stoichiometry: 1.0
species: 732441

816897
type: SpeciesReference
stoichiometry: 1.0
species: 741259

816873
type: SpeciesReference
stoichiometry: 1.0
species: 730922

744868
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: w-hydroxyl leukotriene B4_C20H31O5

031017
type: Reaction
product: 759886
product: 759873
is: ENSCAFG00000014033.2
reactant: 759849
reactant: 759861
notes: R_PPA subsystem: Oxidative Phosphorylation R_PPA equation: [c] : h2o + ppi --> h + (2) pi
is: http://identifiers.org/ec-code/3.6.1.1
fast: false
reversible: false
name: inorganic diphosphatase

759886
type: SpeciesReference
stoichiometry: 1.0
species: 741259

759873
type: SpeciesReference
stoichiometry: 2.0
species: 749200

759849
type: SpeciesReference
stoichiometry: 1.0
species: 741151

759861
type: SpeciesReference
stoichiometry: 1.0
species: 749466

727178
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3-(4-Hydroxyphenyl)pyruvate_C9H7O4

031620
type: Reaction
fast: false
notes: R_CYSTGLUex subsystem: Transport, Extracellular R_CYSTGLUex equation: Lcystin[e] + glu-L[c] --> Lcystin[c] + glu-L[e]
reversible: false
reactant: 764697
name: L-cystine/L-glutamate exchanger
reactant: 764709
product: 764721
is: ENSCAFG00000003749.2
product: 764733

764697
type: SpeciesReference
stoichiometry: 1.0
species: 739987

764709
type: SpeciesReference
stoichiometry: 1.0
species: 729343

729343
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Cystine_C6H12N2O4S2

764721
type: SpeciesReference
stoichiometry: 1.0
species: 739999

739999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Glutamate_C5H8NO4

764733
type: SpeciesReference
stoichiometry: 1.0
species: 729331

729331
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Cystine_C6H12N2O4S2

728655
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5 hydroxy omeprazole_C17H19N3O4S

041021
type: Reaction
reactant: 853856
reversible: false
name: N-acylsphingosine amidohydrolase
fast: false
is: ENSCAFG00000005297.2
product: 853892
notes: R_ASAH1 subsystem: Sphingolipid Metabolism R_ASAH1 equation: [l] : crm_hs + h2o --> Rtotal + sphings
product: 853880
is: http://identifiers.org/ec-code/3.5.1.23
is: ENSCAFG00000023252.1
reactant: 853868
is: ENSCAFG00000023222.1

853856
type: SpeciesReference
stoichiometry: 1.0
species: 734308

853892
type: SpeciesReference
stoichiometry: 1.0
species: 729688

729688
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: R total_CO2FULLR

853880
type: SpeciesReference
stoichiometry: 1.0
species: 751324

751324
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Sphingosine_C18H38NO2

853868
type: SpeciesReference
stoichiometry: 1.0
species: 741187

751832
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: paclitaxel_C47H31NO14

033136
type: Reaction
notes: R_SUCCt4_3 subsystem: Transport, Extracellular R_SUCCt4_3 equation: (3) na1[e] + succ[e] <==> (3) na1[c] + succ[c] R_AKGt4_3 subsystem: Transport, Extracellular R_AKGt4_3 equation: akg[e] + (3) na1[e] <==> akg[c] + (3) na1[c]
reactant: 778650
is: ENSCAFG00000010486.2
product: 778674
product: 778662
fast: false
reactant: 778638
reactant: 778626
reversible: true
product: 778686

778650
type: SpeciesReference
stoichiometry: 1.0
species: 731417

778674
type: SpeciesReference
stoichiometry: 1.0
species: 731405

778662
type: SpeciesReference
stoichiometry: 1.0
species: 751627

751627
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Succinate_C4H4O4

778638
type: SpeciesReference
stoichiometry: 1.0
species: 751639

751639
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Succinate_C4H4O4

778626
type: SpeciesReference
stoichiometry: 6.0
species: 746930

778686
type: SpeciesReference
stoichiometry: 6.0
species: 746918

736207
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065

727263
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-3-Amino-isobutanoate_C4H9NO2

032835
type: Reaction
reactant: 776648
fast: false
is: http://identifiers.org/ec-code/2.6.1.7
product: 776685
notes: R_3HKYNAKGAT subsystem: Tryptophan metabolism R_3HKYNAKGAT equation: [c] : akg + hLkynr --> 42A3HP24DB + glu-L R_KYNAKGAT subsystem: Tryptophan metabolism R_KYNAKGAT equation: [c] : Lkynr + akg --> 4aphdob + glu-L
reactant: 776636
is: ENSCAFG00000020030.2
reversible: false
reactant: 776624
product: 776673
product: 776661

776648
type: SpeciesReference
stoichiometry: 1.0
species: 729368

776685
type: SpeciesReference
stoichiometry: 1.0
species: 727881

776636
type: SpeciesReference
stoichiometry: 1.0
species: 741247

776624
type: SpeciesReference
stoichiometry: 2.0
species: 731405

776673
type: SpeciesReference
stoichiometry: 2.0
species: 739987

776661
type: SpeciesReference
stoichiometry: 1.0
species: 728040

728040
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-(2-Aminophenyl)-2,4-dioxobutanoate_C10H8NO4

738606
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089

728076
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _4-Hydroxy-2-oxoglutarate_C5H4O6

738279
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Formyl-N-acetyl-5-methoxykynurenamine_C13H16N2O4

727588
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Methylimidazole acetaldehyde_C6H8N2O

741572
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Hexadecenoyl-CoA (n-C16:1CoA)_C37H60N7O17P3S

745772
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Mannosyl)7-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1665H2740N20O570P20

746738
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Malonate semialdehyde_C3H3O3

743987
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 35_C241H384N17O205S11X

037786
type: Reaction
reactant: 822598
product: 822683
product: 822647
fast: false
notes: R_H6MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6MTer_L equation: [r] : (0.1) dolmanp_L + m2emgacpail_hs --> (0.1) dolp_L + h + m3emgacpail_hs R_H8MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8MTer_L equation: [r] : (0.1) dolmanp_L + gpi_hs --> (0.1) dolp_L + h + m(em)3gacpail_hs R_H6MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6MTer_U equation: [r] : (0.1) dolmanp_U + m2emgacpail_hs --> (0.1) dolp_U + h + m3emgacpail_hs R_H7MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7MTer_U equation: [r] : (0.1) dolmanp_U + em2emgacpail_hs --> (0.1) dolp_U + h + mem2emgacpail_hs R_H7MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7MTer_L equation: [r] : (0.1) dolmanp_L + em2emgacpail_hs --> (0.1) dolp_L + h + mem2emgacpail_hs R_H8MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8MTer_U equation: [r] : (0.1) dolmanp_U + gpi_hs --> (0.1) dolp_U + h + m(em)3gacpail_hs
is: ENSCAFG00000013105.2
reactant: 822635
reactant: 822586
reversible: false
product: 822707
product: 822695
reactant: 822610
product: 822671
product: 822659
reactant: 822622

822598
type: SpeciesReference
stoichiometry: 2.0
species: 740651

822683
type: SpeciesReference
stoichiometry: 2.0
species: 746146

822647
type: SpeciesReference
stoichiometry: 1.0
species: 736947

822635
type: SpeciesReference
stoichiometry: 1.0
species: 736898

736898
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dolichyl phosphate D-mannose, human liver homolog_C1140H1868O90P10

822586
type: SpeciesReference
stoichiometry: 2.0
species: 737618

822707
type: SpeciesReference
stoichiometry: 6.0
species: 741332

822695
type: SpeciesReference
stoichiometry: 2.0
species: 745519

822610
type: SpeciesReference
stoichiometry: 1.0
species: 736922

736922
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dolichyl phosphate D-mannose, human uterine homolog_C1085H1780O90P10

822671
type: SpeciesReference
stoichiometry: 1.0
species: 736971

822659
type: SpeciesReference
stoichiometry: 2.0
species: 745832

822622
type: SpeciesReference
stoichiometry: 2.0
species: 745471

729295
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Dopachrome_C9H6NO4

038088
type: Reaction
product: 826383
reactant: 826371
is: ENSCAFG00000003574.2
reversible: false
notes: R_PGLer subsystem: Pentose Phosphate Pathway R_PGLer equation: [r] : 6pgl + h2o --> 6pgc + h R_G6PDH2rer subsystem: Pentose Phosphate Pathway R_G6PDH2rer equation: [r] : g6p + nadp <==> 6pgl + h + nadph R_G6PDH1rer subsystem: Pentose Phosphate Pathway R_G6PDH1rer equation: [r] : g6p + nad <==> 6pgl + h + nadh R_G6PDH1er subsystem: Pentose Phosphate Pathway R_G6PDH1er equation: [r] : g6p + nad --> 6pgl + h + nadh
reactant: 826335
is: http://identifiers.org/ec-code/3.1.1.31
modifier: 826482
modifier: 826432
reactant: 826359
modifier: 826506
fast: false
modifier: 826470
modifier: 826494
modifier: 826457
product: 826395
modifier: 826444
product: 826419
reactant: 826347
product: 826407

826383
type: SpeciesReference
stoichiometry: 1.0
species: 728994

826371
type: SpeciesReference
stoichiometry: 1.0
species: 747026

826335
type: SpeciesReference
stoichiometry: 1.0
species: 729018

729018
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _6-phospho-D-glucono-1,5-lactone_C6H9O9P

826359
type: SpeciesReference
stoichiometry: 1.0
species: 741223

826395
type: SpeciesReference
stoichiometry: 1.0
species: 729018

826419
type: SpeciesReference
stoichiometry: 2.0
species: 741332

826347
type: SpeciesReference
stoichiometry: 1.0
species: 739039

826407
type: SpeciesReference
stoichiometry: 1.0
species: 747074

729380
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: L-Pipecolate_C6H11NO2

749176
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phytanyl coa_C41H70N7O17P3S

739717
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053

030609
type: Reaction
product: 756176
reactant: 756104
is: http://identifiers.org/ec-code/3.6.1.6
reversible: false
is: http://identifiers.org/ec-code/3.6.1.15
product: 756164
product: 756224
product: 756152
reactant: 756140
product: 756212
notes: R_NTP3e subsystem: Nucleotides R_NTP3e equation: [e] : gtp + h2o --> gdp + h + pi R_NDP7ex subsystem: Nucleotides R_NDP7ex equation: [e] : h2o + udp --> h + pi + ump R_NDP10ex subsystem: Nucleotides R_NDP10ex equation: [e] : h2o + idp --> h + imp + pi R_NDP3ex subsystem: Nucleotides R_NDP3ex equation: [e] : gdp + h2o --> gmp + h + pi R_NDP8ex subsystem: Nucleotides R_NDP8ex equation: [e] : h2o + utp --> h + pi + udp
reactant: 756092
reactant: 756080
product: 756200
is: ENSCAFG00000005540.2
reactant: 756116
product: 756188
reactant: 756128
fast: false

756176
type: SpeciesReference
stoichiometry: 1.0
species: 742856

742856
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: IMP_C10H11N4O8P

756104
type: SpeciesReference
stoichiometry: 1.0
species: 742720

742720
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: IDP_C10H11N4O11P2

756164
type: SpeciesReference
stoichiometry: 1.0
species: 753145

753145
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: UDP_C9H11N2O12P2

756224
type: SpeciesReference
stoichiometry: 1.0
species: 739668

756152
type: SpeciesReference
stoichiometry: 1.0
species: 740542

756140
type: SpeciesReference
stoichiometry: 1.0
species: 740982

740982
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: GTP_C10H12N5O14P3

756212
type: SpeciesReference
stoichiometry: 5.0
species: 749213

756092
type: SpeciesReference
stoichiometry: 1.0
species: 753145

756080
type: SpeciesReference
stoichiometry: 1.0
species: 753651

756200
type: SpeciesReference
stoichiometry: 5.0
species: 741271

756116
type: SpeciesReference
stoichiometry: 1.0
species: 739668

756188
type: SpeciesReference
stoichiometry: 1.0
species: 753411

756128
type: SpeciesReference
stoichiometry: 5.0
species: 741163

032523
type: Reaction
reversible: false
product: 774029
name: beta-mannosidase, lysosomal
fast: false
is: ENSCAFG00000010769.2
reactant: 774005
is: http://identifiers.org/ec-code/3.2.1.25
product: 774017
notes: R_B_MANNASEly subsystem: N-Glycan Degradation R_B_MANNASEly equation: [l] : h2o + mn --> acgam + man
reactant: 773993

774029
type: SpeciesReference
stoichiometry: 1.0
species: 730427

774005
type: SpeciesReference
stoichiometry: 1.0
species: 741187

774017
type: SpeciesReference
stoichiometry: 1.0
species: 746098

746098
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: D-Mannose_C6H12O6

773993
type: SpeciesReference
stoichiometry: 1.0
species: 746701

746701
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: beta-1,4-mannose-N-acetylglucosamine_C14H25NO11

727227
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: _3',5'-Cyclic GMP_C10H11N5O7P

738750
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)4 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)2 (Cer)1_C84H145N4O50FULLRCO

040381
type: Reaction
modifier: 846512
product: 846402
modifier: 846462
is: http://identifiers.org/ec-code/6.2.1.1
modifier: 846474
reactant: 846390
reactant: 846378
product: 846426
modifier: 846499
is: http://identifiers.org/ec-code/6.2.1.16
fast: false
notes: R_AACOAT subsystem: Propanoate Metabolism R_AACOAT equation: [c] : acac + atp + coa <==> aacoa + amp + ppi R_ACS2 subsystem: Propanoate Metabolism R_ACS2 equation: [c] : atp + coa + ppa --> amp + ppcoa + ppi R_ACS subsystem: Glycolysis/Gluconeogenesis R_ACS equation: [c] : ac + atp + coa --> accoa + amp + ppi
is: ENSCAFG00000006931.2
product: 846414
modifier: 846487
modifier: 846450
reversible: false
reactant: 846354
product: 846438
reactant: 846366

846402
type: SpeciesReference
stoichiometry: 1.0
species: 749430

846390
type: SpeciesReference
stoichiometry: 1.0
species: 749394

846378
type: SpeciesReference
stoichiometry: 2.0
species: 732441

846426
type: SpeciesReference
stoichiometry: 2.0
species: 731755

846414
type: SpeciesReference
stoichiometry: 1.0
species: 730124

846354
type: SpeciesReference
stoichiometry: 2.0
species: 734054

846438
type: SpeciesReference
stoichiometry: 2.0
species: 749466

846366
type: SpeciesReference
stoichiometry: 1.0
species: 729979

035612
type: Reaction
product: 801903
is: ENSCAFG00000025306.1
is: ENSCAFG00000024705.1
is: ENSCAFG00000025592.1
reactant: 801807
product: 801855
is: ENSCAFG00000002857.2
is: ENSCAFG00000024836.1
notes: R_UGT1A9r subsystem: Steroid Metabolism R_UGT1A9r equation: [r] : 5adtststerone + udpglcur --> 5adtststeroneglc + udp R_UGT1A4r subsystem: Steroid Metabolism R_UGT1A4r equation: [r] : tststerone + udpglcur --> tststeroneglc + udp R_UGT1A8r subsystem: Steroid Metabolism R_UGT1A8r equation: [r] : estriol + udpglcur --> estriolglc + udp R_UGT1A3r subsystem: Steroid Metabolism R_UGT1A3r equation: [r] : andrstrn + udpglcur --> andrstrnglc + udp
is: ENSCAFG00000014306.2
reactant: 801831
is: http://identifiers.org/ec-code/2.4.1.17
reactant: 801819
fast: false
is: ENSCAFG00000002836.2
reactant: 801795
product: 801891
is: ENSCAFG00000014300.2
product: 801879
reversible: false
reactant: 801843
product: 801867
is: ENSCAFG00000002831.2

801903
type: SpeciesReference
stoichiometry: 1.0
species: 737774

801807
type: SpeciesReference
stoichiometry: 1.0
species: 737738

737738
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: estriol_C18H24O3

801855
type: SpeciesReference
stoichiometry: 1.0
species: 752914

752914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: testosterone glucuronide_C25H36O8

801831
type: SpeciesReference
stoichiometry: 4.0
species: 753350

801819
type: SpeciesReference
stoichiometry: 1.0
species: 731864

801795
type: SpeciesReference
stoichiometry: 1.0
species: 752878

752878
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Testosterone_C19H28O2

801891
type: SpeciesReference
stoichiometry: 4.0
species: 753206

801879
type: SpeciesReference
stoichiometry: 1.0
species: 728486

728486
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _5alpha-Dihydrotestosterone glucuronide_C25H38O8

801843
type: SpeciesReference
stoichiometry: 1.0
species: 728450

728450
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _5alpha-Dihydrotestosterone_C19H30O2

801867
type: SpeciesReference
stoichiometry: 1.0
species: 731900

752458
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Thiamin triphosphate_C12H16N4O10P3S

744522
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 8_C83H134N7O61SX

740144
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Glyoxylate_C2H1O3

728595
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: (R)-5-Diphosphomevalonate_C6H10O10P2

728233
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4 hydroxy tolbutamide_C12H18N2O4S

727747
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _3-Oxotetradecanoyl-CoA_C35H56N7O18P3S

742139
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 21_C37H55NO38S2

037472
type: Reaction
notes: R_NDP8 subsystem: Nucleotides R_NDP8 equation: [c] : dudp + h2o --> dump + h + pi R_DTMPK subsystem: Nucleotides R_DTMPK equation: [c] : atp + dtmp <==> adp + dtdp
product: 818895
is: ENSCAFG00000013076.2
modifier: 818967
modifier: 818943
fast: false
is: http://identifiers.org/ec-code/3.6.1.6
reactant: 818883
product: 818907
is: http://identifiers.org/ec-code/2.7.4.9
reversible: false
modifier: 818955
modifier: 818931
product: 818919
reactant: 818871

818895
type: SpeciesReference
stoichiometry: 1.0
species: 749200

818883
type: SpeciesReference
stoichiometry: 1.0
species: 741151

818907
type: SpeciesReference
stoichiometry: 1.0
species: 737290

818919
type: SpeciesReference
stoichiometry: 1.0
species: 741259

818871
type: SpeciesReference
stoichiometry: 1.0
species: 737253

751880
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Thiocyanate_CNS

754355
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Zymostenol_C27H46O

748314
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

030909
type: Reaction
reactant: 758666
product: 758678
notes: R_RBFK subsystem: Riboflavin Metabolism R_RBFK equation: [c] : atp + ribflv --> adp + fmn + h
name: riboflavin kinase
product: 758702
is: http://identifiers.org/ec-code/2.7.1.26
reversible: false
fast: false
reactant: 758654
is: ENSCAFG00000001650.2
product: 758690

758666
type: SpeciesReference
stoichiometry: 1.0
species: 732441

758678
type: SpeciesReference
stoichiometry: 1.0
species: 730922

758702
type: SpeciesReference
stoichiometry: 1.0
species: 741259

758654
type: SpeciesReference
stoichiometry: 1.0
species: 750671

750671
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Riboflavin_C17H20N4O6

758690
type: SpeciesReference
stoichiometry: 1.0
species: 738255

735131
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate D (GlcNAc6S-GlcA2S) proteoglycan_C45H64N2O51S5X

743721
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 15_C149H240N10O119S4X

039971
type: Reaction
product: 842230
reactant: 842218
notes: R_COAtm subsystem: Transport, Mitochondrial R_COAtm equation: coa[c] <==> coa[m]
is: ENSCAFG00000013726.2
fast: false
reversible: true
name: CoA transporter

842230
type: SpeciesReference
stoichiometry: 1.0
species: 734091

842218
type: SpeciesReference
stoichiometry: 1.0
species: 734054

749225
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Phosphate_HO4P

037882
type: Reaction
reactant: 823696
product: 823780
fast: false
is: ENSCAFG00000009417.2
reactant: 823720
reactant: 823732
product: 823744
reversible: false
product: 823756
product: 823768
is: ENSCAFG00000018240.2
notes: R_OXAHCOtex subsystem: Transport, Extracellular R_OXAHCOtex equation: (2) hco3[c] + oxa[e] --> (2) hco3[e] + oxa[c] R_SO4HCOtex subsystem: Transport, Extracellular R_SO4HCOtex equation: (2) hco3[c] + so4[e] --> (2) hco3[e] + so4[c] R_CLHCOtex subsystem: Transport, Extracellular R_CLHCOtex equation: cl[e] + (2) hco3[c] --> cl[c] + (2) hco3[e]
reactant: 823708

823696
type: SpeciesReference
stoichiometry: 6.0
species: 741416

823780
type: SpeciesReference
stoichiometry: 6.0
species: 741428

823720
type: SpeciesReference
stoichiometry: 1.0
species: 751214

823732
type: SpeciesReference
stoichiometry: 1.0
species: 733750

823744
type: SpeciesReference
stoichiometry: 1.0
species: 748266

823756
type: SpeciesReference
stoichiometry: 1.0
species: 733738

823768
type: SpeciesReference
stoichiometry: 1.0
species: 751202

751202
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Sulfate_O4S

823708
type: SpeciesReference
stoichiometry: 1.0
species: 748278

748278
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Oxalate_C2O4

750538
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cis-13-retinal_C20H28O

030921
type: Reaction
is: http://identifiers.org/ec-code/2.1.3.3
name: ornithine carbamoyltransferase, irreversible
is: ENSCAFG00000014023.2
product: 758739
reactant: 758714
product: 758751
reactant: 758727
fast: false
notes: R_OCBTm subsystem: Urea cycle/amino group metabolism R_OCBTm equation: [m] : cbp + orn --> citr-L + h + pi
product: 758763
reversible: false

758739
type: SpeciesReference
stoichiometry: 1.0
species: 749249

758714
type: SpeciesReference
stoichiometry: 1.0
species: 748230

758751
type: SpeciesReference
stoichiometry: 1.0
species: 733726

733726
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Citrulline_C6H13N3O3

758727
type: SpeciesReference
stoichiometry: 1.0
species: 733165

758763
type: SpeciesReference
stoichiometry: 1.0
species: 741308

034673
type: Reaction
reactant: 792306
product: 792330
fast: false
reversible: false
notes: R_HSD17B3r subsystem: Steroid Metabolism R_HSD17B3r equation: [r] : andrstndn + h + nadph --> nadp + tststerone
reactant: 792318
is: ENSCAFG00000001218.2
name: testicular 17-beta-hydroxysteroid dehydrogenase
product: 792342
is: http://identifiers.org/ec-code/1.1.1.62
reactant: 792294

792306
type: SpeciesReference
stoichiometry: 1.0
species: 731852

792330
type: SpeciesReference
stoichiometry: 1.0
species: 752878

792318
type: SpeciesReference
stoichiometry: 1.0
species: 741332

792342
type: SpeciesReference
stoichiometry: 1.0
species: 747148

792294
type: SpeciesReference
stoichiometry: 1.0
species: 747209

749646
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Phospho-beta-D-ribosylamine_C5H11NO7P

728559
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: pentaglutamyl folate (DHF)_C39H43N11O18

035433
type: Reaction
fast: false
notes: R_AKGMALtm subsystem: Transport, Mitochondrial R_AKGMALtm equation: akg[m] + mal-L[c] <==> akg[c] + mal-L[m]
product: 800544
product: 800532
name: alpha-ketoglutarate/malate transporter
reactant: 800508
reactant: 800520
reversible: true
is: ENSCAFG00000015836.2

800544
type: SpeciesReference
stoichiometry: 1.0
species: 745916

800532
type: SpeciesReference
stoichiometry: 1.0
species: 731405

800508
type: SpeciesReference
stoichiometry: 1.0
species: 745904

800520
type: SpeciesReference
stoichiometry: 1.0
species: 731429

731393
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _1-alkyldihydroxyacetone phosphate_C3H4O6PFULLRC2H4

728510
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate_C9H11N3O9P

749731
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Progesterone_C21H30O2

732008
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (+)-alpha-Pinene_C10H16

729622
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: R total 3 Coenzyme A_CO2FULLR3C21H31N7O15P3S

730295
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: N-Acetyl-D-galactosamine_C8H15NO6

037182
type: Reaction
reactant: 815630
product: 815726
fast: false
product: 815702
notes: R_GLCNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT2g equation: [g] : hs_pre2 + uacgam --> h + hs_pre3 + udp R_GLCNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT5g equation: [g] : hs_pre8 + uacgam --> h + hs_pre9 + udp R_GLCNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT3g equation: [g] : hs_pre4 + uacgam --> h + hs_pre5 + udp R_GLCNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT4g equation: [g] : hs_pre6 + uacgam --> h + hs_pre7 + udp R_GLCNACT1g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT1g equation: [g] : cs,hs_linkage + uacgam --> h + hs_pre1 + udp
product: 815738
product: 815678
product: 815690
is: ENSCAFG00000008284.2
product: 815714
reactant: 815642
reactant: 815594
reversible: false
reactant: 815654
reactant: 815606
product: 815666
reactant: 815618

815630
type: SpeciesReference
stoichiometry: 1.0
species: 734465

815726
type: SpeciesReference
stoichiometry: 1.0
species: 742455

815702
type: SpeciesReference
stoichiometry: 5.0
species: 741283

815738
type: SpeciesReference
stoichiometry: 1.0
species: 742407

815678
type: SpeciesReference
stoichiometry: 1.0
species: 742479

815690
type: SpeciesReference
stoichiometry: 5.0
species: 753157

815714
type: SpeciesReference
stoichiometry: 1.0
species: 742431

815642
type: SpeciesReference
stoichiometry: 1.0
species: 742467

815594
type: SpeciesReference
stoichiometry: 5.0
species: 753121

815654
type: SpeciesReference
stoichiometry: 1.0
species: 742443

815606
type: SpeciesReference
stoichiometry: 1.0
species: 742419

815666
type: SpeciesReference
stoichiometry: 1.0
species: 742382

815618
type: SpeciesReference
stoichiometry: 1.0
species: 742394

032499
type: Reaction
modifier: 773752
reactant: 773535
is: http://identifiers.org/ec-code/3.2.1.1
product: 773703
reactant: 773415
product: 773691
modifier: 773836
product: 773559
product: 773595
modifier: 773739
modifier: 773860
reactant: 773475
reactant: 773451
reversible: false
reactant: 773403
product: 773607
modifier: 773788
reactant: 773499
product: 773619
product: 773643
reactant: 773523
reactant: 773439
modifier: 773727
modifier: 773896
modifier: 773824
modifier: 773884
product: 773655
product: 773667
reactant: 773547
product: 773679
product: 773571
modifier: 773812
modifier: 773800
product: 773583
modifier: 773848
reactant: 773463
modifier: 773776
reactant: 773487
reactant: 773511
reactant: 773427
modifier: 773715
fast: false
modifier: 773872
product: 773631
notes: R_SERGLYexR subsystem: Transport, Extracellular R_SERGLYexR equation: gly[c] + ser-L[e] <==> gly[e] + ser-L[c] R_THRGLNexR subsystem: Transport, Extracellular R_THRGLNexR equation: gln-L[c] + thr-L[e] <==> gln-L[e] + thr-L[c] R_ALAGLYexR subsystem: Transport, Extracellular R_ALAGLYexR equation: ala-L[e] + gly[c] <==> ala-L[c] + gly[e] R_SERGLNexR subsystem: Transport, Extracellular R_SERGLNexR equation: gln-L[c] + ser-L[e] <==> gln-L[e] + ser-L[c] R_LEUt4 subsystem: Transport, Extracellular R_LEUt4 equation: leu-L[e] + na1[e] --> leu-L[c] + na1[c] R_AMY1e subsystem: Starch and Sucrose Metabolism R_AMY1e equation: [e] : (8) h2o + strch1 --> (8) glc-D + strch2 R_CYSTGLUex subsystem: Transport, Extracellular R_CYSTGLUex equation: Lcystin[e] + glu-L[c] --> Lcystin[c] + glu-L[e] R_THRGLYexR subsystem: Transport, Extracellular R_THRGLYexR equation: gly[c] + thr-L[e] <==> gly[e] + thr-L[c] R_METLEUex subsystem: Transport, Extracellular R_METLEUex equation: leu-L[c] + met-L[e] --> leu-L[e] + met-L[c] R_ALADGLNexR subsystem: Transport, Extracellular R_ALADGLNexR equation: ala-D[e] + gln-L[c] <==> ala-D[c] + gln-L[e] R_CYSGLYex subsystem: Transport, Extracellular R_CYSGLYex equation: cys-L[c] + gly[e] --> cys-L[e] + gly[c] R_AMY2e subsystem: Starch and Sucrose Metabolism R_AMY2e equation: [e] : glygn2 + (8) h2o --> (8) glc-D + glygn4 R_CYSGLUexR subsystem: Transport, Extracellular R_CYSGLUexR equation: cys-L[e] + gln-L[c] <==> cys-L[c] + gln-L[e] R_SERDGLNexR subsystem: Transport, Extracellular R_SERDGLNexR equation: gln-L[c] + ser-D[e] <==> gln-L[e] + ser-D[c] R_ALADGLYexR subsystem: Transport, Extracellular R_ALADGLYexR equation: ala-D[e] + gly[c] <==> ala-D[c] + gly[e] R_SERDGLYexR subsystem: Transport, Extracellular R_SERDGLYexR equation: gly[c] + ser-D[e] <==> gly[e] + ser-D[c] R_ALAGLNexR subsystem: Transport, Extracellular R_ALAGLNexR equation: ala-L[e] + gln-L[c] <==> ala-L[c] + gln-L[e] R_ARGLYSex subsystem: Transport, Extracellular R_ARGLYSex equation: arg-L[e] + ly…
modifier: 773764
is: ENSCAFG00000015495.2

773535
type: SpeciesReference
stoichiometry: 1.0
species: 751530

751530
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: starch, structure 1 (1,6-{7[1,4-Glc], 4[1,4-Glc]})_C66H112O56

773703
type: SpeciesReference
stoichiometry: 1.0
species: 740433

740433
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: glycogen, structure 4 (glycogenin-1,6-{2[1,4-Glc], [1,4-Glc]})_C18H31O16X

773415
type: SpeciesReference
stoichiometry: 1.0
species: 745399

773691
type: SpeciesReference
stoichiometry: 1.0
species: 739999

751058
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Serine_C3H7NO3

773559
type: SpeciesReference
stoichiometry: 1.0
species: 740168

773595
type: SpeciesReference
stoichiometry: 1.0
species: 729331

751070
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: D-Serine_C3H7NO3

773475
type: SpeciesReference
stoichiometry: 16.0
species: 741163

773451
type: SpeciesReference
stoichiometry: 1.0
species: 746303

773403
type: SpeciesReference
stoichiometry: 1.0
species: 729343

773607
type: SpeciesReference
stoichiometry: 16.0
species: 739827

773499
type: SpeciesReference
stoichiometry: 1.0
species: 740180

773619
type: SpeciesReference
stoichiometry: 1.0
species: 746918

773643
type: SpeciesReference
stoichiometry: 1.0
species: 732260

773523
type: SpeciesReference
stoichiometry: 1.0
species: 744784

773439
type: SpeciesReference
stoichiometry: 1.0
species: 744796

773655
type: SpeciesReference
stoichiometry: 1.0
species: 751542

751542
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: starch, structure 2 (1,6-{2[1,4-Glc], [1,4-Glc]})_C18H32O16

773667
type: SpeciesReference
stoichiometry: 1.0
species: 746291

773547
type: SpeciesReference
stoichiometry: 1.0
species: 740409

740409
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]})_C66H111O56X

773679
type: SpeciesReference
stoichiometry: 1.0
species: 744784

773571
type: SpeciesReference
stoichiometry: 1.0
species: 744796

773583
type: SpeciesReference
stoichiometry: 1.0
species: 735228

773463
type: SpeciesReference
stoichiometry: 1.0
species: 746930

773487
type: SpeciesReference
stoichiometry: 1.0
species: 732272

773511
type: SpeciesReference
stoichiometry: 1.0
species: 739987

773427
type: SpeciesReference
stoichiometry: 1.0
species: 735216

773631
type: SpeciesReference
stoichiometry: 1.0
species: 745411

040923
type: Reaction
product: 853446
product: 853374
product: 853422
notes: R_BACCL subsystem: Biotin Metabolism R_BACCL equation: [c] : atp + btn + h --> btamp + ppi R_BTNPLm subsystem: Biotin Metabolism R_BTNPLm equation: [m] : apoC-Lys + btamp --> amp + apoC-Lys_btn + h R_BTNPL subsystem: Biotin Metabolism R_BTNPL equation: [c] : apoC-Lys + btamp --> amp + apoC-Lys_btn + h R_BACCLm subsystem: Biotin Metabolism R_BACCLm equation: [m] : atp + btn + h --> btamp + ppi
reversible: false
reactant: 853290
is: ENSCAFG00000009689.2
reactant: 853338
product: 853458
reactant: 853230
reactant: 853266
product: 853350
fast: false
product: 853386
reactant: 853326
product: 853434
reactant: 853278
reactant: 853242
is: ENSCAFG00000023909.1
reactant: 853302
is: http://identifiers.org/ec-code/6.3.4.15
reactant: 853254
reactant: 853314
product: 853398
product: 853362
product: 853410

853446
type: SpeciesReference
stoichiometry: 1.0
species: 741308

853374
type: SpeciesReference
stoichiometry: 1.0
species: 732793

732793
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Biotinyl-5'-AMP_C20H27N7O9PS

853422
type: SpeciesReference
stoichiometry: 1.0
species: 732780

853290
type: SpeciesReference
stoichiometry: 1.0
species: 732465

853338
type: SpeciesReference
stoichiometry: 1.0
species: 731996

853458
type: SpeciesReference
stoichiometry: 1.0
species: 749466

853230
type: SpeciesReference
stoichiometry: 1.0
species: 731984

853266
type: SpeciesReference
stoichiometry: 1.0
species: 732793

853350
type: SpeciesReference
stoichiometry: 1.0
species: 731803

853386
type: SpeciesReference
stoichiometry: 1.0
species: 731972

731972
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Holocarboxylase (biotin covalent bound to Lys residue of apoC)_C16H27N4O3SX

853326
type: SpeciesReference
stoichiometry: 1.0
species: 741259

853434
type: SpeciesReference
stoichiometry: 1.0
species: 741259

853278
type: SpeciesReference
stoichiometry: 1.0
species: 732817

732817
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Biotin_C10H15N2O3S

853242
type: SpeciesReference
stoichiometry: 1.0
species: 732441

853302
type: SpeciesReference
stoichiometry: 1.0
species: 732780

853254
type: SpeciesReference
stoichiometry: 1.0
species: 732841

853314
type: SpeciesReference
stoichiometry: 1.0
species: 741308

853398
type: SpeciesReference
stoichiometry: 1.0
species: 749478

853362
type: SpeciesReference
stoichiometry: 1.0
species: 731960

731960
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Holocarboxylase (biotin covalent bound to Lys residue of apoC)_C16H27N4O3SX

853410
type: SpeciesReference
stoichiometry: 1.0
species: 731755

034938
type: Reaction
is: ENSCAFG00000001333.2
reactant: 794271
product: 794295
reactant: 794259
name: GDP-L-fucose synthase
notes: R_GFUCS subsystem: Fructose and Mannose Metabolism R_GFUCS equation: [c] : gdpddman + h + nadph --> gdpfuc + nadp
is: http://identifiers.org/ec-code/1.1.1.271
reversible: false
fast: false
product: 794307
reactant: 794283

794271
type: SpeciesReference
stoichiometry: 1.0
species: 741259

794295
type: SpeciesReference
stoichiometry: 1.0
species: 739729

794259
type: SpeciesReference
stoichiometry: 1.0
species: 739717

794307
type: SpeciesReference
stoichiometry: 1.0
species: 747099

794283
type: SpeciesReference
stoichiometry: 1.0
species: 747173

033076
type: Reaction
product: 778409
reactant: 778396
notes: R_MAN6PI subsystem: Fructose and Mannose Metabolism R_MAN6PI equation: [c] : man6p <==> f6p
is: ENSCAFG00000017973.2
is: http://identifiers.org/ec-code/5.3.1.8
fast: false
reversible: true
name: mannose-6-phosphate isomerase

778409
type: SpeciesReference
stoichiometry: 1.0
species: 738015

778396
type: SpeciesReference
stoichiometry: 1.0
species: 746049

037991
type: Reaction
reactant: 825459
notes: R_AMPTASECGe subsystem: Glutathione Metabolism R_AMPTASECGe equation: [e] : cgly + h2o --> cys-L + gly R_AMPTASECG subsystem: Glutathione Metabolism R_AMPTASECG equation: [c] : cgly + h2o --> cys-L + gly
product: 825507
is: http://identifiers.org/ec-code/3.4.11.2
reactant: 825495
product: 825519
reactant: 825483
fast: false
product: 825543
product: 825531
is: ENSCAFG00000012013.2
reversible: false
reactant: 825471

825459
type: SpeciesReference
stoichiometry: 1.0
species: 733274

825507
type: SpeciesReference
stoichiometry: 1.0
species: 740168

825495
type: SpeciesReference
stoichiometry: 1.0
species: 733286

825519
type: SpeciesReference
stoichiometry: 1.0
species: 735216

825483
type: SpeciesReference
stoichiometry: 1.0
species: 741151

825543
type: SpeciesReference
stoichiometry: 1.0
species: 740180

825531
type: SpeciesReference
stoichiometry: 1.0
species: 735228

825471
type: SpeciesReference
stoichiometry: 1.0
species: 741163

036362
type: Reaction
product: 808662
product: 808638
reactant: 808601
notes: R_GAMt1r subsystem: Transport, Extracellular R_GAMt1r equation: gam[e] <==> gam[c] R_GLCt1r subsystem: Transport, Extracellular R_GLCt1r equation: glc-D[e] <==> glc-D[c] R_DHAAt1r subsystem: Transport, Extracellular R_DHAAt1r equation: dhdascb[e] <==> dhdascb[c]
reactant: 808613
product: 808650
fast: false
is: ENSCAFG00000016126.2
reactant: 808626
reversible: true

808662
type: SpeciesReference
stoichiometry: 1.0
species: 739815

808638
type: SpeciesReference
stoichiometry: 1.0
species: 736243

808601
type: SpeciesReference
stoichiometry: 1.0
species: 739827

808613
type: SpeciesReference
stoichiometry: 1.0
species: 736255

808650
type: SpeciesReference
stoichiometry: 1.0
species: 739426

808626
type: SpeciesReference
stoichiometry: 1.0
species: 739438

736716
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _4,8 dimethylnonanoyl carnitine_C18H37NO4

034348
type: Reaction
product: 789289
reversible: false
reactant: 789253
fast: false
is: http://identifiers.org/ec-code/2.7.1.105
is: ENSCAFG00000005194.2
is: ENSCAFG00000012493.2
is: http://identifiers.org/ec-code/3.1.3.46
is: ENSCAFG00000016476.2
product: 789301
reactant: 789265
product: 789313
is: ENSCAFG00000011550.2
product: 789325
product: 789277
reactant: 789241
reactant: 789228
notes: R_FBP26 subsystem: Fructose and Mannose Metabolism R_FBP26 equation: [c] : f26bp + h2o --> f6p + pi R_PFK26 subsystem: Fructose and Mannose Metabolism R_PFK26 equation: [c] : atp + f6p --> adp + f26bp + h

789289
type: SpeciesReference
stoichiometry: 1.0
species: 749200

789253
type: SpeciesReference
stoichiometry: 1.0
species: 738015

789301
type: SpeciesReference
stoichiometry: 1.0
species: 730922

789265
type: SpeciesReference
stoichiometry: 1.0
species: 741151

789313
type: SpeciesReference
stoichiometry: 1.0
species: 738015

789325
type: SpeciesReference
stoichiometry: 1.0
species: 741259

789277
type: SpeciesReference
stoichiometry: 1.0
species: 737991

789241
type: SpeciesReference
stoichiometry: 1.0
species: 732441

789228
type: SpeciesReference
stoichiometry: 1.0
species: 737991

744447
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II boisynthesis, precursor 2_C47H76N4O33X

741030
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Guanine_C5H5N5O

753447
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: UMP_C9H11N2O9P

038840
type: Reaction
is: ENSCAFG00000007869.2
reactant: 831932
notes: R_ATPS4m subsystem: Oxidative Phosphorylation R_ATPS4m equation: adp[m] + (4) h[c] + pi[m] --> atp[m] + (3) h[m] + h2o[m]
is: ENSCAFG00000023984.1
is: ENSCAFG00000017407.2
is: ENSCAFG00000011783.2
is: ENSCAFG00000017648.2
is: ENSCAFG00000013366.2
is: ENSCAFG00000018265.2
reversible: false
is: ENSCAFG00000012218.2
is: ENSCAFG00000006490.2
fast: false
is: ENSCAFG00000023681.1
name: ATP synthase (four protons for one ATP)
is: ENSCAFG00000019536.2
is: http://identifiers.org/ec-code/3.6.3.14
is: ENSCAFG00000000377.1
is: ENSCAFG00000001530.2
is: ENSCAFG00000004703.2
is: ENSCAFG00000006136.2
product: 831944
product: 831956
is: ENSCAFG00000023193.1
is: ENSCAFG00000025386.1
is: ENSCAFG00000000136.2
is: ENSCAFG00000006712.2
reactant: 831920
is: ENSCAFG00000019738.2
is: ENSCAFG00000007108.2
is: ENSCAFG00000024321.1
is: ENSCAFG00000005024.2
is: ENSCAFG00000013494.2
is: ENSCAFG00000009682.2
product: 831968
reactant: 831908
is: ENSCAFG00000016880.2
is: ENSCAFG00000005930.2

831932
type: SpeciesReference
stoichiometry: 4.0
species: 741259

831944
type: SpeciesReference
stoichiometry: 1.0
species: 741199

831956
type: SpeciesReference
stoichiometry: 1.0
species: 732465

831920
type: SpeciesReference
stoichiometry: 1.0
species: 730946

831968
type: SpeciesReference
stoichiometry: 3.0
species: 741308

831908
type: SpeciesReference
stoichiometry: 1.0
species: 749249

040332
type: Reaction
product: 845559
reversible: true
reactant: 845535
is: ENSCAFG00000020105.2
fast: false
reactant: 845547
is: ENSCAFG00000017744.2
is: http://identifiers.org/ec-code/2.7.4.3
name: adenylate kinase
notes: R_ADK1 subsystem: Nucleotides R_ADK1 equation: [c] : amp + atp <==> (2) adp

845559
type: SpeciesReference
stoichiometry: 2.0
species: 730922

845535
type: SpeciesReference
stoichiometry: 1.0
species: 732441

845547
type: SpeciesReference
stoichiometry: 1.0
species: 731755

752715
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Oxidized thioredoxin_X

729150
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: heptaglutamyl folate (DHF)_C49H55N13O24

034950
type: Reaction
is: http://identifiers.org/ec-code/2.7.8.11
product: 794343
name: phosphatidyl-CMP: glycerophosphate phosphatidyltransferase
product: 794355
reversible: false
notes: R_PGPPT subsystem: Glycerophospholipid Metabolism R_PGPPT equation: [c] : cdpdag_hs + glyc3p --> cmp + h + pgp_hs
fast: false
reactant: 794319
reactant: 794331
is: ENSCAFG00000005312.2
product: 794367

794343
type: SpeciesReference
stoichiometry: 1.0
species: 749019

749019
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphatidyl glycerol phosphate (homo sapiens)_C6H11O9P2FULLRCO2FULLR2CO2

794355
type: SpeciesReference
stoichiometry: 1.0
species: 733859

794319
type: SpeciesReference
stoichiometry: 1.0
species: 740265

794331
type: SpeciesReference
stoichiometry: 1.0
species: 733238

794367
type: SpeciesReference
stoichiometry: 1.0
species: 741259

744916
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Leukotriene D4_C25H39N2O6S

731357
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-amino-1-(5-phospho-D-ribosyl)imidazole_C8H12N3O7P

751251
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Sulfate_O4S

746533
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: _1D-myo-Inositol 1-phosphate_C6H11O9P

738353
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Formate_CH1O2

035143
type: Reaction
product: 796260
reactant: 796236
reversible: false
reactant: 796212
fast: false
product: 796284
product: 796272
is: ENSCAFG00000018994.2
notes: R_DHCR243r subsystem: Cholesterol Metabolism R_DHCR243r equation: [r] : dsmsterol + fadh2 --> chsterol + fad R_DHCR242r subsystem: Cholesterol Metabolism R_DHCR242r equation: [r] : chlstol + fadh2 --> fad + lthstrl R_DHCR241r subsystem: Cholesterol Metabolism R_DHCR241r equation: [r] : fadh2 + zymst --> fad + zymstnl
product: 796296
reactant: 796224
reactant: 796248

796260
type: SpeciesReference
stoichiometry: 1.0
species: 745375

796236
type: SpeciesReference
stoichiometry: 3.0
species: 738099

738099
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

796212
type: SpeciesReference
stoichiometry: 1.0
species: 737079

737079
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Desmosterol_C27H44O

796284
type: SpeciesReference
stoichiometry: 1.0
species: 733618

796272
type: SpeciesReference
stoichiometry: 3.0
species: 738051

738051
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

796296
type: SpeciesReference
stoichiometry: 1.0
species: 754355

796224
type: SpeciesReference
stoichiometry: 1.0
species: 754343

754343
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: zymosterol_C27H44O

796248
type: SpeciesReference
stoichiometry: 1.0
species: 733323

036772
type: Reaction
product: 811734
notes: R_CERT2rt subsystem: Transport, Endoplasmic Reticular R_CERT2rt equation: gluside_hs[c] <==> gluside_hs[r] R_CERT1gt subsystem: Transport, Golgi Apparatus R_CERT1gt equation: crm_hs[c] <==> crm_hs[g] R_CERT2gt subsystem: Transport, Golgi Apparatus R_CERT2gt equation: gluside_hs[c] <==> gluside_hs[g] R_CERT1rt subsystem: Transport, Endoplasmic Reticular R_CERT1rt equation: crm_hs[c] <==> crm_hs[r]
fast: false
product: 811758
product: 811746
is: ENSCAFG00000009478.2
reactant: 811710
reversible: true
reactant: 811722
product: 811770

811734
type: SpeciesReference
stoichiometry: 1.0
species: 734321

811758
type: SpeciesReference
stoichiometry: 1.0
species: 734296

734296
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

811746
type: SpeciesReference
stoichiometry: 1.0
species: 740083

740083
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO

811710
type: SpeciesReference
stoichiometry: 2.0
species: 740071

811722
type: SpeciesReference
stoichiometry: 2.0
species: 734283

811770
type: SpeciesReference
stoichiometry: 1.0
species: 740107

039947
type: Reaction
product: 842050
reactant: 842026
is: ENSCAFG00000019606.2
reactant: 842038
name: hydroxyacylglutathione hydrolase
product: 842062
is: http://identifiers.org/ec-code/3.1.2.6
reversible: false
fast: false
product: 842074
notes: R_GLYOX subsystem: Pyruvate Metabolism R_GLYOX equation: [c] : h2o + lgt-S --> gthrd + h + lac-D

842050
type: SpeciesReference
stoichiometry: 1.0
species: 740922

842026
type: SpeciesReference
stoichiometry: 1.0
species: 745013

842038
type: SpeciesReference
stoichiometry: 1.0
species: 741151

842062
type: SpeciesReference
stoichiometry: 1.0
species: 744598

842074
type: SpeciesReference
stoichiometry: 1.0
species: 741259

750806
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: de-Fuc, reducing GlcNAc removed form of PA6 (w/o peptide linkage)_C76H123N5O57

032017
type: Reaction
name: dihydoorotic acid dehydrogenase (quinone10)
reactant: 769083
product: 769119
fast: false
notes: R_DHORD9 subsystem: Pyrimidine Biosynthesis R_DHORD9 equation: dhor-S[c] + q10[m] --> orot[c] + q10h2[m]
is: ENSCAFG00000020218.2
reversible: false
product: 769107
reactant: 769095

769083
type: SpeciesReference
stoichiometry: 1.0
species: 736413

769119
type: SpeciesReference
stoichiometry: 1.0
species: 748254

748254
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Orotate_C5H3N2O4

769107
type: SpeciesReference
stoichiometry: 1.0
species: 750454

769095
type: SpeciesReference
stoichiometry: 1.0
species: 750429

740578
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: GMP_C10H12N5O8P

743108
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2-keto-3-deoxy-D-glycero-D-galactononic acid 9-phosphate_C9H14O12P

040741
type: Reaction
reactant: 851533
is: http://identifiers.org/ec-code/1.14.13.9
product: 851605
product: 851581
notes: R_KYN3OX subsystem: Tryptophan metabolism R_KYN3OX equation: [c] : Lkynr + h + nadph + o2 --> h2o + hLkynr + nadp
fast: false
product: 851593
is: ENSCAFG00000015726.2
reactant: 851545
name: kynurenine 3-monooxygenase
reversible: false
reactant: 851569
reactant: 851557

851533
type: SpeciesReference
stoichiometry: 1.0
species: 729368

851605
type: SpeciesReference
stoichiometry: 1.0
species: 741151

851581
type: SpeciesReference
stoichiometry: 1.0
species: 741247

851593
type: SpeciesReference
stoichiometry: 1.0
species: 747099

851545
type: SpeciesReference
stoichiometry: 1.0
species: 747698

851569
type: SpeciesReference
stoichiometry: 1.0
species: 747173

851557
type: SpeciesReference
stoichiometry: 1.0
species: 741259

752470
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _2,3,4,5-Tetrahydropyridine-2-carboxylate_C6H8NO2

033730
type: Reaction
is: http://identifiers.org/ec-code/2.4.2.7
reversible: false
product: 783535
is: ENSCAFG00000019865.2
reactant: 783511
name: adenine phosphoribosyltransferase
fast: false
product: 783523
reactant: 783499
notes: R_ADPT subsystem: Salvage Pathway R_ADPT equation: [c] : ade + prpp --> amp + ppi

783535
type: SpeciesReference
stoichiometry: 1.0
species: 749466

783511
type: SpeciesReference
stoichiometry: 1.0
species: 750128

750128
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Phospho-alpha-D-ribose 1-diphosphate_C5H8O14P3

783523
type: SpeciesReference
stoichiometry: 1.0
species: 731755

783499
type: SpeciesReference
stoichiometry: 1.0
species: 730801

739680
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GDP_C10H12N5O11P2

728137
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Hydroxyphenylacetate_C8H7O3

741838
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065

742176
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 24_C31H50NO26

033330
type: Reaction
product: 780025
reversible: true
is: http://identifiers.org/ec-code/4.2.1.3
is: ENSCAFG00000001766.2
reactant: 780013
is: ENSCAFG00000001786.2
name: aconitase
notes: R_ACONT subsystem: Citric Acid Cycle R_ACONT equation: [c] : cit <==> icit
fast: false

780025
type: SpeciesReference
stoichiometry: 1.0
species: 742624

780013
type: SpeciesReference
stoichiometry: 1.0
species: 733678

743914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 2_C87H142N6O62X

748759
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Procollagen 5-hydroxy-L-lysine_C6H14N2O3

036446
type: Reaction
is: http://identifiers.org/ec-code/2.8.2.23
is: ENSCAFG00000017700.2
fast: false
product: 809158
reactant: 809120
notes: R_S3T2g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T2g equation: [g] : hs_pre14 + paps --> h + hs_pre15 + pap
reversible: false
product: 809134
reactant: 809108
name: heparin-glucosamine 3-O-sulfotransferase
product: 809146

809158
type: SpeciesReference
stoichiometry: 1.0
species: 748663

809120
type: SpeciesReference
stoichiometry: 1.0
species: 742357

809134
type: SpeciesReference
stoichiometry: 1.0
species: 741283

809108
type: SpeciesReference
stoichiometry: 1.0
species: 748687

809146
type: SpeciesReference
stoichiometry: 1.0
species: 742369

748218
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Ornithine_C5H13N2O2

740253
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Glycine betaine_C5H11NO2

750974
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Selenate_O4Se

038136
type: Reaction
product: 826736
reactant: 826724
notes: R_TPI subsystem: Glycolysis/Gluconeogenesis R_TPI equation: [c] : dhap <==> g3p
is: ENSCAFG00000014553.2
is: http://identifiers.org/ec-code/5.3.1.1
fast: false
reversible: true
name: triose-phosphate isomerase

826736
type: SpeciesReference
stoichiometry: 1.0
species: 739003

826724
type: SpeciesReference
stoichiometry: 1.0
species: 736111

736111
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dihydroxyacetone phosphate_C3H5O6P

037967
type: Reaction
is: ENSCAFG00000007985.2
reactant: 825302
is: ENSCAFG00000014542.2
is: ENSCAFG00000013924.2
reversible: false
notes: R_PI4PLC subsystem: Inositol Phosphate Metabolism R_PI4PLC equation: [c] : h2o + pail4p_hs --> dag_hs + h + mi14p R_PI45PLC subsystem: Inositol Phosphate Metabolism R_PI45PLC equation: [c] : h2o + pail45p_hs --> dag_hs + h + mi145p R_PIPLC subsystem: Inositol Phosphate Metabolism R_PIPLC equation: [c] : h2o + pail_hs --> dag_hs + h + mi1p-D
product: 825387
reactant: 825326
reactant: 825314
is: ENSCAFG00000014832.2
is: ENSCAFG00000019405.2
is: ENSCAFG00000004760.2
is: ENSCAFG00000004931.2
is: ENSCAFG00000005760.2
is: http://identifiers.org/ec-code/3.1.4.3
is: ENSCAFG00000019989.2
is: ENSCAFG00000010953.2
product: 825338
is: ENSCAFG00000009036.2
is: ENSCAFG00000012538.2
reactant: 825290
fast: false
product: 825375
is: http://identifiers.org/ec-code/3.1.4.11
is: ENSCAFG00000008746.2
is: ENSCAFG00000009082.2
product: 825363
product: 825350
is: ENSCAFG00000010394.2

825302
type: SpeciesReference
stoichiometry: 1.0
species: 748591

825387
type: SpeciesReference
stoichiometry: 3.0
species: 741259

825326
type: SpeciesReference
stoichiometry: 3.0
species: 741151

825314
type: SpeciesReference
stoichiometry: 1.0
species: 748531

825338
type: SpeciesReference
stoichiometry: 3.0
species: 735409

825290
type: SpeciesReference
stoichiometry: 1.0
species: 748507

825375
type: SpeciesReference
stoichiometry: 1.0
species: 746497

746497
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1D-myo-Inositol 1,4-bisphosphate_C6H10O12P2

825363
type: SpeciesReference
stoichiometry: 1.0
species: 746473

825350
type: SpeciesReference
stoichiometry: 1.0
species: 746521

733383
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Choline_C5H14NO

040152
type: Reaction
reactant: 843624
name: sialidase
product: 843648
is: ENSCAFG00000011606.2
fast: false
is: http://identifiers.org/ec-code/3.2.1.18
is: ENSCAFG00000024826.1
notes: R_SIAASE subsystem: N-Glycan Degradation R_SIAASE equation: [c] : (2) h2o + s2l2n2m2mn --> (2) acnam + l2n2m2mn
reactant: 843636
reversible: false
product: 843660

843624
type: SpeciesReference
stoichiometry: 1.0
species: 750794

843648
type: SpeciesReference
stoichiometry: 1.0
species: 744559

744559
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: de-Fuc, reducing GlcNAc removed, de-Sia form of PA6 (w/o peptide linkage)_C54H91N3O41

843636
type: SpeciesReference
stoichiometry: 2.0
species: 741151

843660
type: SpeciesReference
stoichiometry: 2.0
species: 730645

030885
type: Reaction
product: 758496
reversible: false
fast: false
is: http://identifiers.org/ec-code/2.7.1.3
reactant: 758472
product: 758532
product: 758520
is: ENSCAFG00000004673.2
reactant: 758484
reactant: 758460
notes: R_KHK3 subsystem: Galactose metabolism R_KHK3 equation: [c] : atp + tagat-D --> adp + h + tag1p-D R_KHK2 subsystem: Glyoxylate and Dicarboxylate Metabolism R_KHK2 equation: [c] : atp + xylu-D --> adp + h + xu1p-D R_KHK subsystem: Fructose and Mannose Metabolism R_KHK equation: [c] : atp + fru --> adp + f1p + h
product: 758508
reactant: 758448
product: 758544

758496
type: SpeciesReference
stoichiometry: 1.0
species: 754245

754245
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Xylulose 1-phosphate_C5H9O8P

758472
type: SpeciesReference
stoichiometry: 3.0
species: 732441

758532
type: SpeciesReference
stoichiometry: 1.0
species: 737979

737979
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Fructose 1-phosphate_C6H11O9P

758520
type: SpeciesReference
stoichiometry: 3.0
species: 730922

758484
type: SpeciesReference
stoichiometry: 1.0
species: 751783

751783
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Tagatose_C6H12O6

758460
type: SpeciesReference
stoichiometry: 1.0
species: 738474

758508
type: SpeciesReference
stoichiometry: 1.0
species: 751747

751747
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Tagatose 1-phosphate_C6H11O9P

758448
type: SpeciesReference
stoichiometry: 1.0
species: 754305

754305
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Xylulose_C5H10O5

758544
type: SpeciesReference
stoichiometry: 3.0
species: 741259

728860
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: pentaglutamyl folate (THF)_C39H45N11O18

036046
type: Reaction
modifier: 806220
reactant: 806088
modifier: 806292
reactant: 806112
modifier: 806316
reactant: 806124
product: 806196
modifier: 806280
modifier: 806268
product: 806148
reactant: 806063
notes: R_ALCD22_D subsystem: Pyruvate Metabolism R_ALCD22_D equation: [c] : lald-D + nad --> h + mthgxl + nadh R_34DHOXPEGOX subsystem: Tyrosine metabolism R_34DHOXPEGOX equation: [c] : 34dhmald + h + nadh <==> 34dhoxpeg + nad R_ALCD1 subsystem: Miscellaneous R_ALCD1 equation: [c] : meoh + nad <==> fald + h + nadh R_ALCD2if subsystem: Glycolysis/Gluconeogenesis R_ALCD2if equation: [c] : etoh + nad --> acald + h + nadh R_ALCD21_D subsystem: Pyruvate Metabolism R_ALCD21_D equation: [c] : 12ppd-R + nad --> h + lald-D + nadh R_ALCD22_L subsystem: Pyruvate Metabolism R_ALCD22_L equation: [c] : lald-L + nad --> h + mthgxl + nadh R_LALDO subsystem: Pyruvate Metabolism R_LALDO equation: [c] : gthrd + lald-D + nad <==> h + lgt-S + nadh R_ALCD21_L subsystem: Pyruvate Metabolism R_ALCD21_L equation: [c] : 12ppd-S + nad --> h + lald-L + nadh R_FALDH subsystem: Tyrosine metabolism R_FALDH equation: [c] : fald + gthrd + nad <==> Sfglutth + h + nadh
modifier: 806328
is: ENSCAFG00000013007.2
modifier: 806304
is: http://identifiers.org/ec-code/1.1.1.78
modifier: 806256
product: 806136
reactant: 806075
product: 806160
is: http://identifiers.org/ec-code/1.2.1.49
is: http://identifiers.org/ec-code/1.1.1.1
modifier: 806232
is: http://identifiers.org/ec-code/1.2.1.1
modifier: 806244
fast: false
product: 806184
reversible: false
modifier: 806208
reactant: 806100
product: 806172

727106
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3,4-Dihydroxyphenylethyleneglycol_C8H10O4

806088
type: SpeciesReference
stoichiometry: 1.0
species: 726428