MODEL1008120005
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species: 600731
species: 606600
reaction: 010086
species: 594492
species: 604064
species: 608519
reaction: 015607
reaction: 019368
species: 588130
species: 587791
species: 598832
species: 611188
species: 606917
species: 595932
reaction: 009537
reaction: 016615
reaction: 014659
species: 608604
species: 584955
species: 585926
species: 601623
species: 586652
species: 600671
species: 591628
reaction: 017421
species: 585065
species: 588820
species: 609485
species: 585876
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species: 585415
species: 604307
species: 592800
species: 605912
species: 611660
species: 603084
species: 609752
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species: 611126
reaction: 010326
species: 593064
species: 597808
species: 610921
species: 608774
species: 607050
species: 598760
species: 601695
reaction: 018959
species: 605852
reaction: 013718
species: 606540
species: 608247
species: 590053
species: 596612
species: 594468
species: 592872
species: 599000
species: 597047
species: 611066
species: 587152
species: 589374
species: 605358
species: 605708
species: 599325
reaction: 011366
reaction: 018346
species: 593790
species: 600249
species: 595666
reaction: 015403
species: 600200
species: 588530
reaction: 016901
species: 605187
reaction: 019163
species: 600382
reaction: 012535
reaction: 017589

591385
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: (E)-carveol_C10H16O

584341
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

600731
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: heparan sulfate, precursor 7_C73H109N4O58X

584377
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

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type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

584413
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

010086
type: Reaction
is: http://identifiers.org/ec-code/1.4.1.2
product: 626884
product: 626920
reversible: true
product: 626896
reactant: 626848
product: 626932
is: http://identifiers.org/ec-code/1.4.1.4
reactant: 626860
notes: R_GLUDxm subsystem: Glutamate metabolism R_GLUDxm equation: [m] : glu-L + h2o + nad <==> akg + h + nadh + nh4 R_GLUDym subsystem: Glutamate metabolism R_GLUDym equation: [m] : glu-L + h2o + nadp <==> akg + h + nadph + nh4
reactant: 626872
is: ENSECAG00000007371.1
is: ENSECAG00000000539.1
reactant: 626836
fast: false
product: 626908

626884
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species: 605587

605587
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Ammonium_H4N

584401
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

626920
type: SpeciesReference
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species: 599581

599581
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: H+_H

626896
type: SpeciesReference
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species: 589712

589712
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _2-Oxoglutarate_C5H4O5

626848
type: SpeciesReference
stoichiometry: 2.0
species: 598301

598301
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Glutamate_C5H8NO4

626932
type: SpeciesReference
stoichiometry: 1.0
species: 605334

605334
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

626860
type: SpeciesReference
stoichiometry: 1.0
species: 605272

605272
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

626872
type: SpeciesReference
stoichiometry: 1.0
species: 605394

605394
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

626836
type: SpeciesReference
stoichiometry: 2.0
species: 599469

599469
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: H2O_H2O

626908
type: SpeciesReference
stoichiometry: 1.0
species: 605454

605454
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

594492
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353

584353
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

604064
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: (alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C70H117N2O55X

608519
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Putrescine_C4H14N2

015607
type: Reaction
is: ENSECAG00000000263.1
reactant: 677948
reactant: 677924
product: 677984
product: 677960
reactant: 677936
notes: R_UDPGALtg subsystem: Transport, Golgi Apparatus R_UDPGALtg equation: udpgal[c] + ump[g] <==> udpgal[g] + ump[c] R_UGALNACtg subsystem: Transport, Golgi Apparatus R_UGALNACtg equation: udpacgal[c] + ump[g] <==> udpacgal[g] + ump[c]
product: 677972
fast: false
reversible: true

677948
type: SpeciesReference
stoichiometry: 1.0
species: 611477

611477
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341

677924
type: SpeciesReference
stoichiometry: 1.0
species: 611562

611562
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: UDPgalactose_C15H22N2O17P2

677984
type: SpeciesReference
stoichiometry: 1.0
species: 611574

611574
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: UDPgalactose_C15H22N2O17P2

677960
type: SpeciesReference
stoichiometry: 2.0
species: 611660

611660
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: UMP_C9H11N2O9P

677936
type: SpeciesReference
stoichiometry: 2.0
species: 611684

611684
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: UMP_C9H11N2O9P

677972
type: SpeciesReference
stoichiometry: 1.0
species: 611489

611489
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377

019368
type: Reaction
reactant: 715430
product: 715479
notes: R_SMPD3g subsystem: Sphingolipid Metabolism R_SMPD3g equation: [g] : h2o + sphmyln_hs --> cholp + crm_hs + h R_SMPD3l subsystem: Sphingolipid Metabolism R_SMPD3l equation: [l] : h2o + sphmyln_hs --> cholp + crm_hs + h
product: 715515
is: ENSECAG00000000185.1
reactant: 715454
product: 715491
product: 715539
reactant: 715442
product: 715503
reversible: false
fast: false
reactant: 715466
product: 715527

715430
type: SpeciesReference
stoichiometry: 1.0
species: 609629

609629
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO

715479
type: SpeciesReference
stoichiometry: 1.0
species: 599556

599556
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: H+_H

715515
type: SpeciesReference
stoichiometry: 1.0
species: 591821

591821
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Choline phosphate_C5H13NO4P

715454
type: SpeciesReference
stoichiometry: 1.0
species: 599445

599445
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: H2O_H2O

715491
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stoichiometry: 1.0
species: 599568

599568
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: H+_H

584389
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

715539
type: SpeciesReference
stoichiometry: 1.0
species: 592583

592583
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

715442
type: SpeciesReference
stoichiometry: 1.0
species: 609641

609641
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO

715503
type: SpeciesReference
stoichiometry: 1.0
species: 592595

592595
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

715466
type: SpeciesReference
stoichiometry: 1.0
species: 599457

599457
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: H2O_H2O

715527
type: SpeciesReference
stoichiometry: 1.0
species: 591833

591833
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Choline phosphate_C5H13NO4P

588130
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: T antigen (core 1)_C14H24NO10X

587791
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: R group 2 Coenzyme A homo sapiens_XCO2C21H31N7O15P3S

598832
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GMP_C10H12N5O8P

611188
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: testosterone sulfate_C19H27O5S

606917
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Adenosine 3',5'-bisphosphate_C10H11N5O10P2

595932
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: (phosphoethanolaminyl-mannosyl),(phosphoethanolaminyl)-dimannosyl-glucosaminyl-acylphosphatidylinositol (H7')_C53H100N3O35P3FULLRCO2FULLR2CO2

009537
type: Reaction
is: ENSECAG00000001612.1
reversible: true
is: http://identifiers.org/ec-code/1.1.1.105
reactant: 621587
product: 621635
product: 621647
fast: false
product: 621611
notes: R_RDH2a subsystem: Vitamin A Metabolism R_RDH2a equation: [c] : nadp + retinol-9-cis <==> h + nadph + retinal-cis-9 R_RDH1a subsystem: Vitamin A Metabolism R_RDH1a equation: [c] : nadp + retinol <==> h + nadph + retinal
product: 621623
reactant: 621575
reactant: 621599

621587
type: SpeciesReference
stoichiometry: 1.0
species: 608847

608847
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _9-cis-retinol_C20H30O

621635
type: SpeciesReference
stoichiometry: 2.0
species: 599531

599531
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: H+_H

621647
type: SpeciesReference
stoichiometry: 2.0
species: 605442

605442
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

621611
type: SpeciesReference
stoichiometry: 1.0
species: 608835

608835
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Retinal_C20H28O

621623
type: SpeciesReference
stoichiometry: 1.0
species: 608823

608823
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: cis-9-retinal_C20H28O

621575
type: SpeciesReference
stoichiometry: 2.0
species: 605370

605370
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

621599
type: SpeciesReference
stoichiometry: 1.0
species: 608883

608883
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Retinol_C20H30O

016615
type: Reaction
reactant: 688792
product: 688914
product: 688878
product: 688950
product: 688938
reversible: true
product: 688974
product: 688902
notes: R_THYOXt subsystem: Transport, Extracellular R_THYOXt equation: hco3[c] + thyox-L[e] <==> hco3[e] + thyox-L[c] R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_GCHOLAt subsystem: Transport, Extracellular R_GCHOLAt equation: gchola[e] + hco3[c] <==> gchola[c] + hco3[e] R_PROSTGE2t subsystem: Transport, Extracellular R_PROSTGE2t equation: hco3[c] + prostge2[e] <==> hco3[e] + prostge2[c] R_CHOLATEt subsystem: Transport, Extracellular R_CHOLATEt equation: cholate[e] + hco3[c] <==> cholate[c] + hco3[e] R_TRIODTHYt subsystem: Transport, Extracellular R_TRIODTHYt equation: hco3[c] + triodthy[e] <==> hco3[e] + triodthy[c] R_DHEASt subsystem: Transport, Extracellular R_DHEASt equation: dheas[e] + hco3[c] <==> dheas[c] + hco3[e] R_TCHOLAt subsystem: Transport, Extracellular R_TCHOLAt equation: hco3[c] + tchola[e] <==> hco3[e] + tchola[c] R_ESTRADIOLGLCt subsystem: Transport, Extracellular R_ESTRADIOLGLCt equation: estradiolglc[e] + hco3[c] <==> estradiolglc[c] + hco3[e]
reactant: 688841
product: 688926
reactant: 688866
reactant: 688804
product: 688962
reactant: 688780
fast: false
is: ENSECAG00000017481.1
product: 688986
reactant: 688853
reactant: 688829
reactant: 688768
product: 688890
reactant: 688816
reactant: 688756

688792
type: SpeciesReference
stoichiometry: 1.0
species: 610860

610860
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Thyroxine_C15H11I4NO4

584365
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

688914
type: SpeciesReference
stoichiometry: 1.0
species: 594576

594576
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dehydroepiandrosterone sulfate_C19H27O5S

688878
type: SpeciesReference
stoichiometry: 1.0
species: 596125

596125
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Estrone 3-sulfate_C18H21O5S

688950
type: SpeciesReference
stoichiometry: 1.0
species: 597795

597795
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: glycocholate_C26H43NO6

688938
type: SpeciesReference
stoichiometry: 1.0
species: 610848

610848
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Thyroxine_C15H11I4NO4

688974
type: SpeciesReference
stoichiometry: 1.0
species: 611054

611054
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Triiodothyronine_C15H12I3NO4

688902
type: SpeciesReference
stoichiometry: 1.0
species: 595980

595980
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: estradiol glucuronide_C24H32O8

688841
type: SpeciesReference
stoichiometry: 1.0
species: 611066

611066
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Triiodothyronine_C15H12I3NO4

688926
type: SpeciesReference
stoichiometry: 1.0
species: 610115

610115
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: taurocholic acid_C26H45NO7S

688866
type: SpeciesReference
stoichiometry: 1.0
species: 596138

596138
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Estrone 3-sulfate_C18H21O5S

688804
type: SpeciesReference
stoichiometry: 1.0
species: 597808

597808
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: glycocholate_C26H43NO6

688962
type: SpeciesReference
stoichiometry: 1.0
species: 591700

591700
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Cholate_C24H39O5

688780
type: SpeciesReference
stoichiometry: 9.0
species: 599689

599689
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Bicarbonate_CHO3

688986
type: SpeciesReference
stoichiometry: 9.0
species: 599701

599701
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Bicarbonate_CHO3

688853
type: SpeciesReference
stoichiometry: 1.0
species: 595992

595992
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: estradiol glucuronide_C24H32O8

688829
type: SpeciesReference
stoichiometry: 1.0
species: 591712

591712
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Cholate_C24H39O5

688768
type: SpeciesReference
stoichiometry: 1.0
species: 594588

594588
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Dehydroepiandrosterone sulfate_C19H27O5S

688890
type: SpeciesReference
stoichiometry: 1.0
species: 608271

608271
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Prostaglandin E2_C20H31O5

688816
type: SpeciesReference
stoichiometry: 1.0
species: 608283

608283
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Prostaglandin E2_C20H31O5

688756
type: SpeciesReference
stoichiometry: 1.0
species: 610127

610127
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: taurocholic acid_C26H45NO7S

014659
type: Reaction
reversible: false
name: Fucokinase
product: 668616
notes: R_FK subsystem: Fructose and Mannose Metabolism R_FK equation: [c] : atp + fuc-L --> adp + fuc1p-L + h
reactant: 668604
product: 668628
product: 668640
fast: false
reactant: 668592
is: http://identifiers.org/ec-code/2.7.1.52
is: ENSECAG00000012351.1

668616
type: SpeciesReference
stoichiometry: 1.0
species: 596829

596829
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Fucose 1-phosphate_C6H11O8P

668604
type: SpeciesReference
stoichiometry: 1.0
species: 596841

596841
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Fucose_C6H12O5

668628
type: SpeciesReference
stoichiometry: 1.0
species: 589206

589206
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: ADP_C10H12N5O10P2

668640
type: SpeciesReference
stoichiometry: 1.0
species: 599531

668592
type: SpeciesReference
stoichiometry: 1.0
species: 590727

590727
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: ATP_C10H12N5O13P3

608604
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Pyridoxine_C8H11NO3

584955
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _1-Pyrroline-5-carboxylate_C5H6NO2

585926
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: (S)-3-Methyl-2-oxopentanoate_C6H9O3

601623
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 27_C104H169N7O88S4

586652
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _4-Trimethylammoniobutanoate_C7H15NO2

600671
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: heparan sulfate, precursor 2_C37H56NO31X

591628
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Choline_C5H14NO

017421
type: Reaction
reactant: 696577
product: 696637
is: ENSECAG00000001013.1
reactant: 696589
reactant: 696565
fast: false
product: 696601
product: 696625
product: 696613
notes: R_BMTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_BMTer_L equation: [r] : (0.1) dolmanp_L + memgacpail_hs --> (0.1) dolp_L + h + m2emgacpail_hs R_BMTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_BMTer_U equation: [r] : (0.1) dolmanp_U + memgacpail_hs --> (0.1) dolp_U + h + m2emgacpail_hs R_H3MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3MTer_L equation: [r] : (0.1) dolmanp_L + m2gacpail_hs --> (0.1) dolp_L + h + m3gacpail_hs R_H3MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3MTer_U equation: [r] : (0.1) dolmanp_U + m2gacpail_hs --> (0.1) dolp_U + h + m3gacpail_hs
product: 696649
reactant: 696553
reversible: false

696577
type: SpeciesReference
stoichiometry: 1.0
species: 595206

595206
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Dolichyl phosphate D-mannose, human uterine homolog_C1085H1780O90P10

696637
type: SpeciesReference
stoichiometry: 2.0
species: 603734

603734
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: (dimannosyl),(phosphoethanolaminyl)-mannosyl-glucosylaminyl-acylphosphatidylinositol (H6)_C51H94N2O32P2FULLRCO2FULLR2CO2

696589
type: SpeciesReference
stoichiometry: 1.0
species: 595181

595181
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Dolichyl phosphate D-mannose, human liver homolog_C1140H1868O90P10

696565
type: SpeciesReference
stoichiometry: 2.0
species: 603746

603746
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: dimannosyl-glucosaminyl-acylphosphatidylinositol (H3)_C43H78NO24PFULLRCO2FULLR2CO2

696601
type: SpeciesReference
stoichiometry: 1.0
species: 595230

595230
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Dolichol phosphate, human liver homolog_C1080H1758O40P10

696625
type: SpeciesReference
stoichiometry: 1.0
species: 595254

595254
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Dolichol phosphate, human uterine homolog_C1025H1670O40P10

696613
type: SpeciesReference
stoichiometry: 2.0
species: 603794

603794
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: trimannosyl-glucosaminyl-acylphosphatidylinositol (H4)_C49H88NO29PFULLRCO2FULLR2CO2

696649
type: SpeciesReference
stoichiometry: 4.0
species: 599605

599605
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: H+_H

696553
type: SpeciesReference
stoichiometry: 2.0
species: 604439

604439
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: (mannosyl),(phosphoethanolaminyl)-mannosyl-glucosylaminyl-acylphosphatidylinositol (B)_C45H84N2O27P2FULLRCO2FULLR2CO2

585065
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _2-Aminoacrylate_C3H5NO2

588820
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Acetylcholine_C7H16NO2

609485
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Sulfate_O4S

585876
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Methylimidazole acetaldehyde_C6H8N2O

585415
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3,4-Dihydroxyphenylacetate_C8H7O4

604307
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Mannose 1-phosphate_C6H11O9P

592800
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 1_C45H68N2O43S2

605912
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Nervonyl carnitine_C31H59NO4

603084
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Leukotriene A4_C20H29O3

609752
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S

596276
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Fructose 2,6-bisphosphate_C6H10O12P2

611126
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Testosterone_C19H28O2

010326
type: Reaction
product: 628936
product: 628875
reactant: 628790
reactant: 628851
product: 628949
product: 628887
is: http://identifiers.org/ec-code/2.3.1.7
reactant: 628766
product: 628924
reactant: 628839
product: 628899
reversible: true
reactant: 628802
reactant: 628778
product: 628962
product: 628911
notes: R_CSNATp subsystem: Fatty Acid Metabolism R_CSNATp equation: [x] : accoa + crn <==> acrn + coa R_CSNATer subsystem: Fatty Acid Metabolism R_CSNATer equation: [r] : accoa + crn <==> acrn + coa R_CSNAT3x subsystem: Carnitine shuttle R_CSNAT3x equation: [x] : crn + ppcoa <==> coa + pcrn R_CSNAT2m subsystem: Carnitine shuttle R_CSNAT2m equation: [m] : coa + pcrn <==> crn + ppcoa R_CSNAT2x subsystem: Fatty Acid Metabolism R_CSNAT2x equation: [x] : crn + dmnoncoa <==> coa + dmnoncrn R_CSNATm subsystem: Fatty Acid Metabolism R_CSNATm equation: [m] : acrn + coa <==> accoa + crn
reactant: 628754
reactant: 628815
fast: false
is: ENSECAG00000010205.1
reactant: 628827
product: 628863

628936
type: SpeciesReference
stoichiometry: 1.0
species: 607703

607703
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Propanoyl-CoA_C24H36N7O17P3S

628875
type: SpeciesReference
stoichiometry: 1.0
species: 592402

592402
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Coenzyme A_C21H32N7O16P3S

628790
type: SpeciesReference
stoichiometry: 1.0
species: 589049

589049
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: O-Acetylcarnitine_C9H17NO4

628851
type: SpeciesReference
stoichiometry: 1.0
species: 592668

592668
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: L-Carnitine_C7H15NO3

628949
type: SpeciesReference
stoichiometry: 1.0
species: 595000

595000
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: _4,8 dimethylnonanoyl carnitine_C18H37NO4

584425
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

628887
type: SpeciesReference
stoichiometry: 1.0
species: 589061

589061
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: O-Acetylcarnitine_C9H17NO4

628766
type: SpeciesReference
stoichiometry: 1.0
species: 607074

607074
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: propionyl-carnitine_C10H19NO4

628924
type: SpeciesReference
stoichiometry: 1.0
species: 589073

589073
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: O-Acetylcarnitine_C9H17NO4

628839
type: SpeciesReference
stoichiometry: 1.0
species: 588470

588470
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Acetyl-CoA_C23H34N7O17P3S

628899
type: SpeciesReference
stoichiometry: 1.0
species: 607086

607086
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: propionyl-carnitine_C10H19NO4

628802
type: SpeciesReference
stoichiometry: 1.0
species: 588457

588457
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Acetyl-CoA_C23H34N7O17P3S

628778
type: SpeciesReference
stoichiometry: 1.0
species: 607715

607715
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Propanoyl-CoA_C24H36N7O17P3S

628962
type: SpeciesReference
stoichiometry: 2.0
species: 592656

592656
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Carnitine_C7H15NO3

628911
type: SpeciesReference
stoichiometry: 1.0
species: 588432

588432
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Acetyl-CoA_C23H34N7O17P3S

628754
type: SpeciesReference
stoichiometry: 1.0
species: 594988

594988
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S

628815
type: SpeciesReference
stoichiometry: 2.0
species: 592378

592378
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Coenzyme A_C21H32N7O16P3S

628827
type: SpeciesReference
stoichiometry: 3.0
species: 592680

592680
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: L-Carnitine_C7H15NO3

628863
type: SpeciesReference
stoichiometry: 3.0
species: 592414

592414
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Coenzyme A_C21H32N7O16P3S

593064
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 2_C37H53NO44S4

610921
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: timnodonyl coenzyme A_C41H60N7O17P3S

608774
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: alpha-D-Ribose 5-phosphate_C5H9O8P

607050
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Phosphocreatine_C4H9N3O5P

598760
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GM1b (homo sapiens)_C55H95N3O30FULLRCO

601695
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 32_C82H135N5O67S2

018959
type: Reaction
product: 711921
reactant: 711885
product: 711933
notes: R_GPIDAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIDAer equation: [r] : gpi_prot_hs + h2o --> dgpi_prot_hs + h + hdca R_GPIDA2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIDA2er equation: [r] : em2emgacpail_prot_hs + h2o --> dem2emgacpail_prot_hs + h + hdca
fast: false
reversible: false
reactant: 711873
product: 711897
is: ENSECAG00000019980.1
product: 711909
reactant: 711861

711921
type: SpeciesReference
stoichiometry: 1.0
species: 594300

594300
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: deacylated-glycophosphatidylinositol (GPI)-anchored protein_C39H76N4O37P4FULLRCO2FULLR2CO2X

711885
type: SpeciesReference
stoichiometry: 1.0
species: 595908

595908
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353

711933
type: SpeciesReference
stoichiometry: 2.0
species: 599605

711873
type: SpeciesReference
stoichiometry: 1.0
species: 598940

598940
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: glycophosphatidylinositol (GPI)-anchored protein_C55H106N4O38P4FULLRCO2FULLR2CO2X

711897
type: SpeciesReference
stoichiometry: 2.0
species: 599773

599773
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Hexadecanoate (n-C16:0)_C16H31O2

711909
type: SpeciesReference
stoichiometry: 1.0
species: 594190

594190
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353

711861
type: SpeciesReference
stoichiometry: 2.0
species: 599493

599493
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: H2O_H2O

605852
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: nervonic acid_C24H45O2

013718
type: Reaction
product: 660454
fast: false
product: 660418
is: http://identifiers.org/ec-code/2.3.1.9
product: 660442
product: 660430
reactant: 660394
reversible: true
is: ENSECAG00000020128.1
reactant: 660406
notes: R_ACACT10m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ACACT10m equation: [m] : 2maacoa + coa <==> accoa + ppcoa R_ACACT1rm subsystem: Tryptophan metabolism R_ACACT1rm equation: [m] : (2) accoa <==> aacoa + coa
reactant: 660382

660454
type: SpeciesReference
stoichiometry: 1.0
species: 607703

660418
type: SpeciesReference
stoichiometry: 1.0
species: 588203

588203
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Acetoacetyl-CoA_C25H36N7O18P3S

660442
type: SpeciesReference
stoichiometry: 1.0
species: 592378

660430
type: SpeciesReference
stoichiometry: 1.0
species: 588432

660394
type: SpeciesReference
stoichiometry: 1.0
species: 585235

585235
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401

660406
type: SpeciesReference
stoichiometry: 1.0
species: 592378

660382
type: SpeciesReference
stoichiometry: 2.0
species: 588432

606540
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Oxalate_C2O4

608247
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Prostaglandin E1_C20H33O5

590053
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: AMP_C10H12N5O7P

596612
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Formate_CH1O2

594468
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353

592872
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), degradation product 1_C45H67N2O46S3

599000
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Geranyl diphosphate_C10H17O7P2

597047
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)1 (Cer)1_C78H135N4O46FULLRCO

587152
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: pentaglutamyl folate (THF)_C39H45N11O18

589374
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: adrenic acid_C22H35O2

605358
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

605708
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C54H90N3O40X

599325
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: carbonic acid_H2CO3

011366
type: Reaction
reactant: 637575
is: http://identifiers.org/ec-code/1.14.11.18
product: 637623
is: ENSECAG00000017688.1
name: Phytanoyl-CoA dioxygenase, peroxisomal
reversible: false
product: 637611
is: ENSECAG00000004121.1
fast: false
product: 637599
reactant: 637563
notes: R_PHYHx subsystem: Fatty acid oxidation, peroxisome R_PHYHx equation: [x] : akg + o2 + phytcoa --> co2 + phyt2ohcoa + succ
reactant: 637587

637575
type: SpeciesReference
stoichiometry: 1.0
species: 607450

607450
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: phytanyl coa_C41H70N7O17P3S

637623
type: SpeciesReference
stoichiometry: 1.0
species: 607401

607401
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: _2-Hydroxyphytanoyl-CoA_C41H70N7O18P3S

637611
type: SpeciesReference
stoichiometry: 1.0
species: 609945

609945
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Succinate_C4H4O4

637599
type: SpeciesReference
stoichiometry: 1.0
species: 592318

592318
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: CO2_CO2

637563
type: SpeciesReference
stoichiometry: 1.0
species: 606021

606021
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: O2_O2

637587
type: SpeciesReference
stoichiometry: 1.0
species: 589736

589736
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: _2-Oxoglutarate_C5H4O5

018346
type: Reaction
product: 703928
product: 703868
reactant: 703748
reactant: 703736
product: 703904
reactant: 703796
product: 703844
reactant: 703724
product: 703952
reactant: 703808
reactant: 703784
reactant: 703772
product: 703880
reversible: false
reactant: 703760
reactant: 703712
product: 703856
product: 703892
reactant: 703700
product: 703832
notes: R_THRt4 subsystem: Transport, Extracellular R_THRt4 equation: na1[e] + thr-L[e] --> na1[c] + thr-L[c] R_LEUt4 subsystem: Transport, Extracellular R_LEUt4 equation: leu-L[e] + na1[e] --> leu-L[c] + na1[c] R_SERt4 subsystem: Transport, Extracellular R_SERt4 equation: na1[e] + ser-L[e] --> na1[c] + ser-L[c] R_ALAt4 subsystem: Transport, Extracellular R_ALAt4 equation: ala-L[e] + na1[e] --> ala-L[c] + na1[c] R_PROt4 subsystem: Transport, Extracellular R_PROt4 equation: na1[e] + pro-L[e] --> na1[c] + pro-L[c] R_ASNt4 subsystem: Transport, Extracellular R_ASNt4 equation: asn-L[e] + na1[e] --> asn-L[c] + na1[c] R_METt4 subsystem: Transport, Extracellular R_METt4 equation: met-L[e] + na1[e] --> met-L[c] + na1[c] R_GLYt4 subsystem: Transport, Extracellular R_GLYt4 equation: gly[e] + na1[e] --> gly[c] + na1[c] R_PHEt4 subsystem: Transport, Extracellular R_PHEt4 equation: na1[e] + phe-L[e] --> na1[c] + phe-L[c] R_GLNt4 subsystem: Transport, Extracellular R_GLNt4 equation: gln-L[e] + na1[e] --> gln-L[c] + na1[c]
product: 703916
product: 703940
fast: false
is: ENSECAG00000007576.1
reactant: 703820

703928
type: SpeciesReference
stoichiometry: 1.0
species: 589834

589834
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Alanine_C3H7NO2

703868
type: SpeciesReference
stoichiometry: 10.0
species: 605187

605187
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Sodium_Na

703748
type: SpeciesReference
stoichiometry: 10.0
species: 605200

605200
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Sodium_Na

703736
type: SpeciesReference
stoichiometry: 1.0
species: 604572

604572
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Methionine_C5H11NO2S

703904
type: SpeciesReference
stoichiometry: 1.0
species: 603048

603048
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Leucine_C6H13NO2

703796
type: SpeciesReference
stoichiometry: 1.0
species: 598217

598217
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Glutamine_C5H10N2O3

703844
type: SpeciesReference
stoichiometry: 1.0
species: 609352

609352
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Serine_C3H7NO3

703724
type: SpeciesReference
stoichiometry: 1.0
species: 590631

590631
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Asparagine_C4H8N2O3

703952
type: SpeciesReference
stoichiometry: 1.0
species: 608138

608138
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Proline_C5H9NO2

703808
type: SpeciesReference
stoichiometry: 1.0
species: 609364

609364
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Serine_C3H7NO3

703784
type: SpeciesReference
stoichiometry: 1.0
species: 610764

610764
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Threonine_C4H9NO3

703772
type: SpeciesReference
stoichiometry: 1.0
species: 598458

598458
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Glycine_C2H5NO2

703880
type: SpeciesReference
stoichiometry: 1.0
species: 590619

590619
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Asparagine_C4H8N2O3

703760
type: SpeciesReference
stoichiometry: 1.0
species: 608150

608150
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Proline_C5H9NO2

703712
type: SpeciesReference
stoichiometry: 1.0
species: 589847

589847
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Alanine_C3H7NO2

703856
type: SpeciesReference
stoichiometry: 1.0
species: 598205

598205
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Glutamine_C5H10N2O3

703892
type: SpeciesReference
stoichiometry: 1.0
species: 604560

604560
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Methionine_C5H11NO2S

703700
type: SpeciesReference
stoichiometry: 1.0
species: 603060

603060
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Leucine_C6H13NO2

703832
type: SpeciesReference
stoichiometry: 1.0
species: 598446

598446
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Glycine_C2H5NO2

703916
type: SpeciesReference
stoichiometry: 1.0
species: 610752

610752
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Threonine_C4H9NO3

703940
type: SpeciesReference
stoichiometry: 1.0
species: 607292

607292
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Phenylalanine_C9H11NO2

703820
type: SpeciesReference
stoichiometry: 1.0
species: 607304

607304
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Phenylalanine_C9H11NO2

593790
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: dATP_C10H12N5O12P3

600249
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Hydroxypyruvate_C3H3O4

595666
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: dUTP_C9H11N2O14P3

015403
type: Reaction
reactant: 675711
fast: false
is: http://identifiers.org/ec-code/2.3.2.2
reactant: 675723
name: Gamma-glutamyltransferase 5
notes: R_GGT5r subsystem: Eicosanoid Metabolism R_GGT5r equation: [r] : h2o + leuktrC4 <==> glu-L + leuktrD4
product: 675747
reversible: true
is: ENSECAG00000021670.1
product: 675735

675711
type: SpeciesReference
stoichiometry: 1.0
species: 603168

603168
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Leukotriene C4_C30H45N3O9S

675723
type: SpeciesReference
stoichiometry: 1.0
species: 599493

675747
type: SpeciesReference
stoichiometry: 1.0
species: 598314

598314
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: L-Glutamate_C5H8NO4

675735
type: SpeciesReference
stoichiometry: 1.0
species: 603180

603180
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Leukotriene D4_C25H39N2O6S

600200
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: heptadecanoyl coa_C38H64N7O17P3S

588530
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: N-Acetyl-L-glutamyl 5-phosphate_C7H9NO8P

016901
type: Reaction
reversible: false
product: 691050
product: 691038
product: 691014
reactant: 690990
is: ENSECAG00000015059.1
is: ENSECAG00000007898.1
reactant: 690978
notes: R_PRGNLONESULT subsystem: Steroid Metabolism R_PRGNLONESULT equation: [c] : paps + prgnlone --> h + pap + prgnlones R_CHSTEROLSULT subsystem: Steroid Metabolism R_CHSTEROLSULT equation: [c] : chsterol + paps --> chsterols + h + pap
reactant: 691002
is: http://identifiers.org/ec-code/2.8.2.2
fast: false
product: 691026

691050
type: SpeciesReference
stoichiometry: 2.0
species: 599531

691038
type: SpeciesReference
stoichiometry: 1.0
species: 607970

607970
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: pregnenolone sulfate_C21H31O5S

691014
type: SpeciesReference
stoichiometry: 2.0
species: 606917

690990
type: SpeciesReference
stoichiometry: 2.0
species: 606941

606941
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3'-Phosphoadenylyl sulfate_C10H11N5O13P2S

690978
type: SpeciesReference
stoichiometry: 1.0
species: 607934

607934
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Pregnenolone_C21H32O2

691002
type: SpeciesReference
stoichiometry: 1.0
species: 591845

591845
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Cholesterol_C27H46O

691026
type: SpeciesReference
stoichiometry: 1.0
species: 591917

591917
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: cholesterol sulfate_C27H45O4S

019163
type: Reaction
name: lysophospholipase
product: 713945
notes: R_LPASE subsystem: Glycerophospholipid Metabolism R_LPASE equation: [c] : h2o + lpchol_hs --> Rtotal + g3pc + h
product: 713933
reversible: false
fast: false
product: 713921
is: ENSECAG00000024810.1
reactant: 713897
reactant: 713909

713945
type: SpeciesReference
stoichiometry: 1.0
species: 599531

713933
type: SpeciesReference
stoichiometry: 1.0
species: 597300

597300
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: sn-Glycero-3-phosphocholine_C8H20NO6P

713921
type: SpeciesReference
stoichiometry: 1.0
species: 587949

587949
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: R total_CO2FULLR

713897
type: SpeciesReference
stoichiometry: 1.0
species: 599421

599421
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: H2O_H2O

713909
type: SpeciesReference
stoichiometry: 1.0
species: 603602

603602
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: lysophosphatidylcholine (homo sapiens)_C8H19NO5PFULLRCO2

600382
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: heparan sulfate, degradation product 19_C43H67N2O42S2

012535
type: Reaction
is: ENSECAG00000016577.1
reactant: 648191
product: 648217
notes: R_URIK1 subsystem: Pyrimidine Biosynthesis R_URIK1 equation: [c] : atp + uri --> adp + h + ump R_CYTDK1 subsystem: Nucleotides R_CYTDK1 equation: [c] : atp + cytd --> adp + cmp + h
product: 648229
is: http://identifiers.org/ec-code/2.7.1.48
is: ENSECAG00000015649.1
product: 648241
reactant: 648165
fast: false
reactant: 648178
reversible: false
product: 648204

648191
type: SpeciesReference
stoichiometry: 1.0
species: 611841

611841
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Uridine_C9H12N2O6

648217
type: SpeciesReference
stoichiometry: 1.0
species: 611660

648229
type: SpeciesReference
stoichiometry: 2.0
species: 589206

648241
type: SpeciesReference
stoichiometry: 2.0
species: 599531

648165
type: SpeciesReference
stoichiometry: 2.0
species: 590727

648178
type: SpeciesReference
stoichiometry: 1.0
species: 593560

593560
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Cytidine_C9H13N3O5

648204
type: SpeciesReference
stoichiometry: 1.0
species: 592147

592147
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: CMP_C9H12N3O8P

017589
type: Reaction
modifier: 698098
is: ENSECAG00000002116.1
modifier: 698074
modifier: 697989
notes: R_THFt2 subsystem: Transport, Extracellular R_THFt2 equation: oh1[c] + thf[e] <==> oh1[e] + thf[c] R_FOLt2 subsystem: Transport, Extracellular R_FOLt2 equation: fol[e] + oh1[c] <==> fol[c] + oh1[e] R_5MTHFt2 subsystem: Transport, Extracellular R_5MTHFt2 equation: _5mthf[e] + oh1[c] <==> 5mthf[c] + oh1[e] R_THMMPt4 subsystem: Transport, Extracellular R_THMMPt4 equation: oh1[c] + thmmp[e] <==> oh1[e] + thmmp[c] R_THMTPt subsystem: Transport, Extracellular R_THMTPt equation: (3) oh1[e] + thmtp[c] --> (3) oh1[c] + thmtp[e] R_5FTHFt2 subsystem: Transport, Extracellular R_5FTHFt2 equation: _5fthf[e] + oh1[c] <==> 5fthf[c] + oh1[e]
modifier: 698013
modifier: 698049
modifier: 697965
reactant: 697929
product: 697941
reactant: 697917
product: 697953
modifier: 698086
fast: false
reversible: false
modifier: 698025
modifier: 698062
modifier: 697977
modifier: 698001
modifier: 698037

587104
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5-Methyltetrahydrofolate_C20H24N7O6

606407
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: hydroxide ion_HO

610680
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Thiamin monophosphate_C12H16N4O4PS

586910
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5-Formyltetrahydrofolate_C20H21N7O7

610692
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Thiamin monophosphate_C12H16N4O4PS

587116
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: _5-Methyltetrahydrofolate_C20H24N7O6

697929
type: SpeciesReference
stoichiometry: 3.0
species: 606419

606419
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: hydroxide ion_HO

697941
type: SpeciesReference
stoichiometry: 1.0
species: 610728

610728
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Thiamin triphosphate_C12H16N4O10P3S

697917
type: SpeciesReference
stoichiometry: 1.0
species: 610716

610716
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Thiamin triphosphate_C12H16N4O10P3S

697953
type: SpeciesReference
stoichiometry: 3.0
species: 606407

610620
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: _5,6,7,8-Tetrahydrofolate_C19H21N7O6

596600
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Folate_C19H18N7O6

596588
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Folate_C19H18N7O6

610608
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5,6,7,8-Tetrahydrofolate_C19H21N7O6

586923
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: _5-Formyltetrahydrofolate_C20H21N7O7

593463
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: CTP_C9H12N3O14P3

600334
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: heparan sulfate, degradation product 15_C49H71N2O57S5

609196
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: Se-Adenosylselenohomocysteine_C14H20N6O5Se

609848
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: stearidonyl coenzyme A_C39H58N7O17P3S

591965
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Citrate_C6H5O7

590787
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: ATP_C10H12N5O13P3

600779
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: hydroxylated taxol_C47H31NO15

010146
type: Reaction
product: 627317
is: ENSECAG00000000603.1
fast: false
product: 627305
reactant: 627281
name: dihydoorotic acid dehydrogenase (quinone10)
reactant: 627293
notes: R_DHORD9 subsystem: Pyrimidine Biosynthesis R_DHORD9 equation: dhor-S[c] + q10[m] --> orot[c] + q10h2[m]
reversible: false

627317
type: SpeciesReference
stoichiometry: 1.0
species: 606516

606516
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Orotate_C5H3N2O4

627305
type: SpeciesReference
stoichiometry: 1.0
species: 608726

608726
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Ubiquinol-10_C59H92O4

627281
type: SpeciesReference
stoichiometry: 1.0
species: 594696

594696
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: (S)-Dihydroorotate_C5H5N2O4

627293
type: SpeciesReference
stoichiometry: 1.0
species: 608702

608702
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Ubiquinone-10_C59H90O4

607679
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Porphobilinogen_C10H13N2O4

019429
type: Reaction
notes: R_RBK subsystem: Pentose Phosphate Pathway R_RBK equation: [c] : atp + rib-D --> adp + h + r5p R_DRBK subsystem: Pentose Phosphate Pathway R_DRBK equation: [c] : atp + drib --> 2dr5p + adp + h
product: 716213
reversible: false
reactant: 716165
product: 716177
product: 716201
reactant: 716153
is: http://identifiers.org/ec-code/2.7.1.15
reactant: 716141
is: ENSECAG00000020582.1
fast: false
product: 716189

716213
type: SpeciesReference
stoichiometry: 2.0
species: 599531

716165
type: SpeciesReference
stoichiometry: 1.0
species: 595339

595339
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Deoxyribose_C5H10O4

716177
type: SpeciesReference
stoichiometry: 1.0
species: 608762

608762
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: alpha-D-Ribose 5-phosphate_C5H9O8P

716201
type: SpeciesReference
stoichiometry: 1.0
species: 585187

585187
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _2-Deoxy-D-ribose 5-phosphate_C5H9O7P

716153
type: SpeciesReference
stoichiometry: 2.0
species: 590727

716141
type: SpeciesReference
stoichiometry: 1.0
species: 608932

608932
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Ribose_C5H10O5

716189
type: SpeciesReference
stoichiometry: 2.0
species: 589206

611889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: Uridine_C9H12N2O6

604778
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: _1D-myo-Inositol 1,4-bisphosphate_C6H10O12P2

609136
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Sarcosine_C3H7NO2

594020
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: dCTP_C9H12N3O13P3

014466
type: Reaction
reactant: 667446
reversible: false
reactant: 667434
name: Core 2 acetylglucosaminyltransferase, Golgi apparatus
notes: R_CORE2GTg subsystem: O-Glycan Biosynthesis R_CORE2GTg equation: [g] : T_antigen + uacgam --> core2 + h + udp
is: http://identifiers.org/ec-code/2.4.1.102
is: ENSECAG00000005515.1
product: 667458
product: 667482
fast: false
product: 667470

667446
type: SpeciesReference
stoichiometry: 1.0
species: 588130

667434
type: SpeciesReference
stoichiometry: 1.0
species: 611381

611381
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377

667458
type: SpeciesReference
stoichiometry: 1.0
species: 611417

611417
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: UDP_C9H11N2O12P2

667482
type: SpeciesReference
stoichiometry: 1.0
species: 592438

592438
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Core 2_C22H37N2O15X

667470
type: SpeciesReference
stoichiometry: 1.0
species: 599556

608404
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: phosphatidylserine (homo sapiens)_C6H11NO6PFULLRCO2FULLR2CO2

012645
type: Reaction
product: 649382
reactant: 649369
notes: R_RPE subsystem: Pentose Phosphate Pathway R_RPE equation: [c] : ru5p-D <==> xu5p-D
is: ENSECAG00000000002.1
is: http://identifiers.org/ec-code/5.1.3.1
fast: false
reversible: true
name: ribulose 5-phosphate 3-epimerase

649382
type: SpeciesReference
stoichiometry: 1.0
species: 612524

612524
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Xylulose 5-phosphate_C5H9O8P

649369
type: SpeciesReference
stoichiometry: 1.0
species: 608968

608968
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Ribulose 5-phosphate_C5H9O8P

603710
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: alpha-D-mannosyl-beta-D-mannosyl-diacylchitobiosyldiphosphodolichol, human liver homolog_C1360H2228N20O270P20

606636
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Phenylacetaldehyde_C8H8O

589797
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: D-Alanine_C3H7NO2

604499
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Mercaptolactate_C3H5O3S

584533
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _10-formyltetrahydrofolate-[Glu](7)_C50H57N13O25

011751
type: Reaction
notes: R_N3Tg subsystem: O-Glycan Biosynthesis R_N3Tg equation: [g] : Tn_antigen + udpgal --> T_antigen + h + udp
reversible: false
is: http://identifiers.org/ec-code/2.4.1.122
reactant: 641043
name: N-acetylgalactosamine 3-beta-galactosyltransferase, Golgi apparatus
product: 641079
is: ENSECAG00000013002.1
product: 641067
fast: false
product: 641055
reactant: 641031

641043
type: SpeciesReference
stoichiometry: 1.0
species: 588142

588142
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Tn antigen_C8H14NO5X

641079
type: SpeciesReference
stoichiometry: 1.0
species: 588130

641067
type: SpeciesReference
stoichiometry: 1.0
species: 599556

641055
type: SpeciesReference
stoichiometry: 1.0
species: 611417

641031
type: SpeciesReference
stoichiometry: 1.0
species: 611574

601032
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Isoleucine_C6H13NO2

605563
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Ammonium_H4N

605792
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Normetanephrine_C9H14NO3

605515
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-Acetyl-D-glucosaminyldiphosphodolichol, human uterine homolog_C1105H1810N10O120P20

016511
type: Reaction
is: ENSECAG00000000302.1
fast: false
name: phosphomannomutase
notes: R_PMANM subsystem: Fructose and Mannose Metabolism R_PMANM equation: [c] : man1p <==> man6p
is: ENSECAG00000019902.1
reactant: 688116
product: 688129
reversible: true
is: http://identifiers.org/ec-code/5.4.2.8

688116
type: SpeciesReference
stoichiometry: 1.0
species: 604307

688129
type: SpeciesReference
stoichiometry: 1.0
species: 604319

604319
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Mannose 6-phosphate_C6H11O9P

601166
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: myo-Inositol_C6H12O6

587453
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: heptaglutamyl folate (THF)_C49H57N13O24

585319
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _2-Oxoadipate_C6H6O5

609340
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: D-Serine_C3H7NO3

585731
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Hydroxypropionyl-CoA_C24H36N7O18P3S

610439
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: tetracosatetraenoyl coenzyme A_C45H70N7O17P3S

603324
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Lipoate_C8H14O2S2

607498
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Phosphate_HO4P

605236
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Nicotinate_C6H4NO2

585986
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: _3-Oxododecanoyl-CoA_C33H52N7O18P3S

588747
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: nLc5Cer_C52H92N3O27FULLRCO

600112
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353

W3 CDTF: Fri Feb 03 12:48:01 GMT 2012

603385
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Linoelaidyl carnitine_C25H45NO4

599713
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Bicarbonate_CHO3

009721
type: Reaction
product: 622854
notes: R_ORNDC subsystem: Urea cycle/amino group metabolism R_ORNDC equation: [c] : h + orn --> co2 + ptrc
fast: false
is: http://identifiers.org/ec-code/4.1.1.17
reversible: false
is: ENSECAG00000022690.1
product: 622842
reactant: 622830
name: Ornithine Decarboxylase
reactant: 622818

622854
type: SpeciesReference
stoichiometry: 1.0
species: 608519

622842
type: SpeciesReference
stoichiometry: 1.0
species: 592269

592269
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: CO2_CO2

622830
type: SpeciesReference
stoichiometry: 1.0
species: 599531

622818
type: SpeciesReference
stoichiometry: 1.0
species: 606467

606467
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Ornithine_C5H13N2O2

600828
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Hypoxanthine_C5H4N4O

589170
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Adenosine_C10H13N5O4

607728
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Diphosphate_HO7P2

588506
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Acetone_C3H6O

594708
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: dIDP_C10H11N4O10P2

611938
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: UTP_C9H11N2O15P3

592836
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 4_C31H49NO29S

018142
type: Reaction
name: Putrescine acetyltransferase
product: 702508
product: 702496
is: http://identifiers.org/ec-code/2.3.1.57
fast: false
is: ENSECAG00000021968.1
product: 702520
notes: R_PTRCAT1 subsystem: Arginine and Proline Metabolism R_PTRCAT1 equation: [c] : accoa + ptrc --> aprut + coa + h
is: ENSECAG00000007716.1
reactant: 702484
reactant: 702472
reversible: false

702508
type: SpeciesReference
stoichiometry: 1.0
species: 599531

702496
type: SpeciesReference
stoichiometry: 1.0
species: 592342

592342
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Coenzyme A_C21H32N7O16P3S

702520
type: SpeciesReference
stoichiometry: 1.0
species: 590319

590319
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-Acetylputrescine_C6H15N2O

702484
type: SpeciesReference
stoichiometry: 1.0
species: 608519

702472
type: SpeciesReference
stoichiometry: 1.0
species: 588408

588408
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Acetyl-CoA_C23H34N7O17P3S

611696
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: UMP_C9H11N2O9P

599192
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Reduced glutathione_C10H16N3O6S

593620
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Deoxyadenosine_C10H13N5O3

610884
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: N6,N6,N6-Trimethyl-L-lysine_C9H20N2O2

017493
type: Reaction
name: glycine reversible transport via sodium and chloride symport (2:1:1)
is: ENSECAG00000002225.1
reactant: 697071
product: 697095
notes: R_GLYt7_LPAREN_211_RPAREN_r subsystem: Transport, Extracellular R_GLYt7_LPAREN_211_RPAREN_r equation: cl[e] + gly[e] + (2) na1[e] <==> cl[c] + gly[c] + (2) na1[c]
fast: false
reactant: 697047
product: 697107
reactant: 697059
product: 697083
reversible: true

697071
type: SpeciesReference
stoichiometry: 1.0
species: 592039

592039
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Chloride_Cl

697095
type: SpeciesReference
stoichiometry: 1.0
species: 592027

592027
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Chloride_Cl

697047
type: SpeciesReference
stoichiometry: 2.0
species: 605200

697107
type: SpeciesReference
stoichiometry: 2.0
species: 605187

697059
type: SpeciesReference
stoichiometry: 1.0
species: 598458

697083
type: SpeciesReference
stoichiometry: 1.0
species: 598446

013334
type: Reaction
fast: false
product: 655979
product: 655991
is: http://identifiers.org/ec-code/1.1.1.40
reactant: 655955
notes: R_ME2m subsystem: Pyruvate Metabolism R_ME2m equation: [m] : mal-L + nadp --> co2 + nadph + pyr
is: ENSECAG00000007798.1
product: 656003
reactant: 655967
name: malic enzyme (NADP), mitochondrial
reversible: false

655979
type: SpeciesReference
stoichiometry: 1.0
species: 592294

592294
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: CO2_CO2

655991
type: SpeciesReference
stoichiometry: 1.0
species: 608665

608665
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Pyruvate_C3H3O3

655955
type: SpeciesReference
stoichiometry: 1.0
species: 604185

604185
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Malate_C4H4O5

656003
type: SpeciesReference
stoichiometry: 1.0
species: 605454

655967
type: SpeciesReference
stoichiometry: 1.0
species: 605394

611200
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Thiosulfate_O3S2

009697
type: Reaction
product: 622722
reactant: 622686
reactant: 622674
fast: false
is: ENSECAG00000002749.1
product: 622710
notes: R_TKT2 subsystem: Pentose Phosphate Pathway R_TKT2 equation: [c] : e4p + xu5p-D <==> f6p + g3p R_TKT1 subsystem: Pentose Phosphate Pathway R_TKT1 equation: [c] : r5p + xu5p-D <==> g3p + s7p
reactant: 622698
reversible: true
is: http://identifiers.org/ec-code/2.2.1.1
is: ENSECAG00000021992.1
product: 622734
is: ENSECAG00000005863.1

622722
type: SpeciesReference
stoichiometry: 1.0
species: 596300

596300
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Fructose 6-phosphate_C6H11O9P

622686
type: SpeciesReference
stoichiometry: 1.0
species: 608762

622674
type: SpeciesReference
stoichiometry: 1.0
species: 595714

595714
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Erythrose 4-phosphate_C4H7O7P

622710
type: SpeciesReference
stoichiometry: 2.0
species: 597288

597288
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Glyceraldehyde 3-phosphate_C3H5O6P

622698
type: SpeciesReference
stoichiometry: 2.0
species: 612524

622734
type: SpeciesReference
stoichiometry: 1.0
species: 609088

609088
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Sedoheptulose 7-phosphate_C7H13O10P

017193
type: Reaction
fast: false
product: 693376
reactant: 693364
notes: R_PPAP subsystem: Triacylglycerol Synthesis R_PPAP equation: [c] : h2o + pa_hs --> dag_hs + pi
is: http://identifiers.org/ec-code/3.1.3.4
is: ENSECAG00000022423.1
is: ENSECAG00000008648.1
reversible: false
is: ENSECAG00000023296.1
name: phosphatidic acid phosphatase
reactant: 693352
product: 693389

693376
type: SpeciesReference
stoichiometry: 1.0
species: 593692

593692
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2

693364
type: SpeciesReference
stoichiometry: 1.0
species: 599421

693352
type: SpeciesReference
stoichiometry: 1.0
species: 606564

606564
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

693389
type: SpeciesReference
stoichiometry: 1.0
species: 607462

607462
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Phosphate_HO4P

604149
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Malonyl-[acyl-carrier protein]_C14H22N2O10PRS

018407
type: Reaction
is: ENSECAG00000022022.1
reactant: 704517
product: 704613
reactant: 704348
reactant: 704457
is: ENSECAG00000022249.1
is: ENSECAG00000025117.1
product: 704625
product: 704794
reactant: 704396
product: 704637
reactant: 704493
is: ENSECAG00000012393.1
product: 704649
product: 704553
reactant: 704445
reactant: 704288
reactant: 704529
product: 704589
reactant: 704409
reactant: 704312
product: 704770
reversible: false
product: 704661
reactant: 704384
product: 704782
is: http://identifiers.org/ec-code/2.4.1.38
product: 704673
reactant: 704505
reactant: 704360
product: 704710
product: 704685
product: 704565
product: 704722
product: 704697
product: 704577
product: 704734
reactant: 704433
fast: false
product: 704806
reactant: 704481
reactant: 704469
product: 704818
reactant: 704541
product: 704601
reactant: 704300
reactant: 704372
reactant: 704336
product: 704746
reactant: 704324
notes: R_G14Tg subsystem: N-Glycan Biosynthesis R_G14Tg equation: [g] : fn2m2masn + (2) udpgal --> (2) h + l2fn2m2masn + (2) udp R_G14T7g subsystem: Keratan sulfate biosynthesis R_G14T7g equation: [g] : ksi_pre5 + udpgal --> h + ksi_pre6 + udp R_G14T21g subsystem: Keratan sulfate biosynthesis R_G14T21g equation: [g] : ksii_core4_pre9 + udpgal --> h + ksii_core4_pre10 + udp R_G14T13g subsystem: Keratan sulfate biosynthesis R_G14T13g equation: [g] : ksi_pre23 + udpgal --> h + ksi_pre24 + udp R_G14T17g subsystem: Keratan sulfate biosynthesis R_G14T17g equation: [g] : ksi_pre35 + udpgal --> h + ksi_pre36 + udp R_G14T20g subsystem: Keratan sulfate biosynthesis R_G14T20g equation: [g] : ksii_core4_pre6 + udpgal --> h + ksii_core4_pre7 + udp R_G14T16g subsystem: Keratan sulfate biosynthesis R_G14T16g equation: [g] : ksi_pre32 + udpgal --> h + ksi_pre33 + udp R_G14T3g subsystem: Keratan sulfate biosynthesis R_G14T3g equation: [g] : ksii_core2_pre3 + udpgal --> h + ksii_core2_pre4 + udp R_G14T10g subsystem: Keratan sulfate biosynthesis R_G14T10g equation: [g] : ksi_pre14 + udpgal --> h + ksi_pre15 + udp R_G14T12g subsystem: Keratan sulfate biosynthesis R_G14T12g equation: [g] : ksi_pre20 + udpgal --> h + ksi_pre21 + udp R_G14T15g subsystem: Keratan sulfate biosynthesis R_G14T15g equation: [g] : ksi_pre29 + udpgal --> h + ksi_pre30 + udp R_G14T9g subsystem: Keratan sulfate biosynthesis R_G14T9g equation: [g] : ksi_pre11 + udpgal --> h + ksi_pre12 + udp R_G14T2g subsystem: Keratan sulfate biosynthesis R_G14T2g equation: [g] : ksii_core2_pre1 + udpgal --> h + ksii_core2_pre2 + udp R_G14T6g subsystem: Keratan sulfate biosynthesis R_G14T6g equation: [g] : ksi_pre2 + udpgal --> h + ksi_pre3 + udp R_G14T19g subsystem: Keratan sulfate biosynthesis R_G14T19g equation: [g] : ksii_core4_pre3 + udpgal --> h + ksii_core4_pre4 + udp R_G14T4g subsystem: Keratan sulfate biosynthesis R_G14T4g equation: [g] : ksii_core2_pre6 + udpgal --> h + ksii_core2_pre7 + udp R_G14T8g subsystem: Keratan sulfate …
reactant: 704421
product: 704758

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704613
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initial amount: NaN
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602518
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601961
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species: 602506

602506
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704445
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602543
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species: 602736

602736
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704529
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602616
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boundary condition: false
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602287
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602142
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704312
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602808
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602748
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602820
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initial concentration: NaN
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602555
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602348
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species: 601949

601949
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704710
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species: 602361

602361
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species: 602238

602238
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initial concentration: NaN
initial amount: NaN
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species: 602700

602700
type: Species
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initial concentration: NaN
initial amount: NaN
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name: keratan sulfate II biosynthesis, precursor 10_C89H143N7O69S2X

704722
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species: 602591

602591
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate II biosynthesis, precursor 7_C67H108N5O51SX

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species: 602034

602034
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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704577
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species: 602154

602154
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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704734
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species: 601998

601998
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: keratan sulfate I biosynthesis, precursor 15_C149H240N10O119S4X

704433
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species: 602226

602226
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: keratan sulfate I biosynthesis, precursor 32_C227H362N16O192S10X

704806
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species: 602323

602323
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boundary condition: false
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initial concentration: NaN
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name: keratan sulfate I biosynthesis, precursor 6_C107H174N7O80SX

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species: 602262

602262
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constant: false
boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: keratan sulfate I biosynthesis, precursor 35_C241H384N17O205S11X

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species: 602070

602070
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initial concentration: NaN
initial amount: NaN
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name: keratan sulfate I biosynthesis, precursor 20_C171H274N12O140S6X

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species: 602082

602082
type: Species
constant: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 21_C177H284N12O145S6X

704541
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species: 602772

602772
type: Species
constant: false
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initial concentration: NaN
initial amount: NaN
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name: keratan sulfate II biosynthesis, precursor 6_C69H111N6O51SX

704601
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species: 602784

602784
type: Species
constant: false
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initial concentration: NaN
initial amount: NaN
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name: keratan sulfate II biosynthesis, precursor 7_C75H121N6O56SX

704300
type: SpeciesReference
stoichiometry: 1.0
species: 592462

592462
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Core 4_C24H40N3O15X

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stoichiometry: 1.0
species: 596552

596552
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: N4-{N-Acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,3)-[N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,6)]-beta-D-mannosyl-(1,4)-N-acetyl-beta-D-glucosaminyl-(1,4)-[alpha-L-fucosyl-(1,6)]-N-acetyl-beta-D-glucosaminyl}asparagine_C56H93N4O39X

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species: 602022

602022
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 17_C157H252N11O127S5X

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type: SpeciesReference
stoichiometry: 1.0
species: 602275

602275
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 36_C247H394N17O210S11X

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species: 602311

602311
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 5_C101H164N7O75SX

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species: 602190

602190
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 2_C87H142N6O62X

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stoichiometry: 1.0
species: 602530

602530
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate II biosynthesis, precursor 2_C39H63N3O28X

584629
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _11-Deoxycortisol_C21H30O4

594648
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _7,8-Dihydrofolate_C19H19N7O6

586960
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5-Hydroxyindoleacetaldehyde_C10H9NO2

605888
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: nervonyl coenzyme A_C45H76N7O17P3S

011896
type: Reaction
notes: R_ETF subsystem: Fatty acid oxidation R_ETF equation: [m] : etfox + fadh2 --> etfrd + fad
reversible: false
name: electron transfer flavoprotein
product: 642091
reactant: 642067
product: 642079
is: ENSECAG00000002611.1
reactant: 642055
fast: false
is: ENSECAG00000015091.1

642091
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stoichiometry: 1.0
species: 596324

596324
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

642067
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stoichiometry: 1.0
species: 596372

596372
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

642079
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stoichiometry: 1.0
species: 596174

596174
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Electron transfer flavoprotein reduced_RH2

642055
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species: 596162

596162
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Electron transfer flavoprotein oxidized_R

587020
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5-Hydroxy-L-tryptophan_C11H12N2O3

598326
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: _5-L-Glutamyl-L-alanine_C8H13N2O5

587188
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: pentaglutamyl folate (THF)_C39H45N11O18

008668
type: Reaction
reactant: 613745
product: 613805
product: 613841
reactant: 613757
reactant: 613769
reactant: 613781
product: 613829
is: ENSECAG00000015421.1
reversible: false
product: 613853
is: http://identifiers.org/ec-code/2.3.1.65
product: 613793
is: ENSECAG00000012860.1
fast: false
notes: R_BAAT1x subsystem: Bile Acid Biosynthesis R_BAAT1x equation: [x] : cholcoa + gly --> coa + gchola R_BAAT4x subsystem: Bile Acid Biosynthesis R_BAAT4x equation: [x] : dcholcoa + gly --> coa + gdchola R_BAAT2x subsystem: Bile Acid Biosynthesis R_BAAT2x equation: [x] : cholcoa + taur --> coa + tchola R_BAAT3x subsystem: Bile Acid Biosynthesis R_BAAT3x equation: [x] : dgcholcoa + gly --> coa + dgchol R_BAAT5x subsystem: Bile Acid Biosynthesis R_BAAT5x equation: [x] : dcholcoa + taur --> coa + tdchola
reactant: 613733
product: 613817

613745
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stoichiometry: 1.0
species: 594215

594215
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425

613805
type: SpeciesReference
stoichiometry: 5.0
species: 592414

613841
type: SpeciesReference
stoichiometry: 1.0
species: 597928

597928
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: glycochenodeoxycholate_C26H43NO5

613757
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stoichiometry: 3.0
species: 598494

598494
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Glycine_C2H5NO2

613769
type: SpeciesReference
stoichiometry: 2.0
species: 610091

610091
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Taurine_C2H7NO3S

613781
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stoichiometry: 2.0
species: 593875

593875
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: chenodeoxycholoyl coenzyme a_C45H70N7O19P3S

613829
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stoichiometry: 1.0
species: 610175

610175
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: taurochenodeoxycholate_C26H45NO6S

613853
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stoichiometry: 1.0
species: 594202

594202
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Chenodeoxyglycocholate_C26H43NO5

613793
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stoichiometry: 1.0
species: 610139

610139
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: taurocholic acid_C26H45NO7S

613733
type: SpeciesReference
stoichiometry: 2.0
species: 591724

591724
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Choloyl-CoA_C45H70N7O20P3S

613817
type: SpeciesReference
stoichiometry: 1.0
species: 597820

597820
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: glycocholate_C26H43NO6

010508
type: Reaction
name: phosphoserine transaminase
notes: R_PSERT subsystem: Glycine, Serine, and Threonine Metabolism R_PSERT equation: [c] : 3php + glu-L --> akg + pser-L
product: 630788
product: 630800
reversible: false
reactant: 630776
is: http://identifiers.org/ec-code/2.6.1.52
reactant: 630764
is: ENSECAG00000017903.1
fast: false

630788
type: SpeciesReference
stoichiometry: 1.0
species: 589688

589688
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _2-Oxoglutarate_C5H4O5

630800
type: SpeciesReference
stoichiometry: 1.0
species: 608441

608441
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: O-Phospho-L-serine_C3H6NO6P

630776
type: SpeciesReference
stoichiometry: 1.0
species: 598265

598265
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Glutamate_C5H8NO4

630764
type: SpeciesReference
stoichiometry: 1.0
species: 586070

586070
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Phosphohydroxypyruvate_C3H2O7P

014261
type: Reaction
product: 665832
reactant: 665796
reactant: 665784
is: ENSECAG00000011520.1
is: ENSECAG00000024615.1
reversible: true
reactant: 665808
notes: R_NRPPHRt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_NRPPHRt4_LPAREN_2_RPAREN_r equation: (2) na1[e] + nrpphr[e] <==> (2) na1[c] + nrpphr[c] R_DOPAt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_DOPAt4_LPAREN_2_RPAREN_r equation: dopa[e] + (2) na1[e] <==> dopa[c] + (2) na1[c]
product: 665844
fast: false
product: 665820

665832
type: SpeciesReference
stoichiometry: 4.0
species: 605187

665796
type: SpeciesReference
stoichiometry: 4.0
species: 605200

665784
type: SpeciesReference
stoichiometry: 1.0
species: 595279

595279
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Dopamine_C8H12NO2

665808
type: SpeciesReference
stoichiometry: 1.0
species: 605828

605828
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Norepinephrine_C8H12NO3

665844
type: SpeciesReference
stoichiometry: 1.0
species: 595266

595266
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dopamine_C8H12NO2

665820
type: SpeciesReference
stoichiometry: 1.0
species: 605816

605816
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Norepinephrine_C8H12NO3

019236
type: Reaction
product: 714464
is: ENSECAG00000015009.1
fast: false
notes: R_UDPGD subsystem: Starch and Sucrose Metabolism R_UDPGD equation: [c] : h2o + (2) nad + udpg --> (3) h + (2) nadh + udpglcur
name: UDPglucose 6-dehydrogenase
reactant: 714404
reactant: 714428
product: 714452
reactant: 714416
reversible: false
product: 714440
is: http://identifiers.org/ec-code/1.1.1.22

714464
type: SpeciesReference
stoichiometry: 2.0
species: 605322

605322
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

714404
type: SpeciesReference
stoichiometry: 2.0
species: 605248

605248
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

714428
type: SpeciesReference
stoichiometry: 1.0
species: 599421

714452
type: SpeciesReference
stoichiometry: 3.0
species: 599531

714416
type: SpeciesReference
stoichiometry: 1.0
species: 611525

611525
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: UDPglucose_C15H22N2O17P2

714440
type: SpeciesReference
stoichiometry: 1.0
species: 611586

611586
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: UDP-D-glucuronate_C15H19N2O18P2

010677
type: Reaction
reactant: 632307
name: glutamine-fructose-6-phosphate transaminase
is: ENSECAG00000019938.1
product: 632331
is: ENSECAG00000009303.1
reactant: 632295
fast: false
notes: R_GF6PTA subsystem: Aminosugar Metabolism R_GF6PTA equation: [c] : f6p + gln-L --> gam6p + glu-L
reversible: false
is: http://identifiers.org/ec-code/2.6.1.16
product: 632319

632307
type: SpeciesReference
stoichiometry: 1.0
species: 596300

632331
type: SpeciesReference
stoichiometry: 1.0
species: 598265

632295
type: SpeciesReference
stoichiometry: 1.0
species: 598205

632319
type: SpeciesReference
stoichiometry: 1.0
species: 597698

597698
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Glucosamine 6-phosphate_C6H13NO8P

611745
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Uroporphyrinogen III_C40H36N4O16

011269
type: Reaction
reactant: 636959
reversible: true
notes: R_SUCCt4_3 subsystem: Transport, Extracellular R_SUCCt4_3 equation: (3) na1[e] + succ[e] <==> (3) na1[c] + succ[c] R_AKGt4_3 subsystem: Transport, Extracellular R_AKGt4_3 equation: akg[e] + (3) na1[e] <==> akg[c] + (3) na1[c]
product: 636995
is: ENSECAG00000010298.1
product: 636983
product: 637007
reactant: 636971
reactant: 636947
fast: false

636959
type: SpeciesReference
stoichiometry: 1.0
species: 609908

609908
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Succinate_C4H4O4

636995
type: SpeciesReference
stoichiometry: 1.0
species: 589688

636983
type: SpeciesReference
stoichiometry: 1.0
species: 609896

609896
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Succinate_C4H4O4

637007
type: SpeciesReference
stoichiometry: 6.0
species: 605187

636971
type: SpeciesReference
stoichiometry: 1.0
species: 589700

589700
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: _2-Oxoglutarate_C5H4O5

636947
type: SpeciesReference
stoichiometry: 6.0
species: 605200

599965
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Hexacosanoyl-CoA (n-C26:0CoA)_C47H82N7O17P3S

011474
type: Reaction
reactant: 638381
notes: R_ACONT subsystem: Citric Acid Cycle R_ACONT equation: [c] : cit <==> icit
product: 638393
is: ENSECAG00000014846.1
fast: false
is: http://identifiers.org/ec-code/4.2.1.3
reversible: true
is: ENSECAG00000016731.1
name: aconitase

638381
type: SpeciesReference
stoichiometry: 1.0
species: 591965

638393
type: SpeciesReference
stoichiometry: 1.0
species: 600900

600900
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Isocitrate_C6H5O7

595364
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Desmosterol_C27H44O

592920
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: chondroitin sulfate B (IdoA2S-GalNAc4S), precursor 4_C45H67N2O42S2X

010881
type: Reaction
modifier: 634235
is: ENSECAG00000016854.1
reactant: 634115
modifier: 634163
reactant: 634103
fast: false
modifier: 634211
notes: R_FACOAL150 subsystem: Fatty acid activation R_FACOAL150 equation: [c] : atp + coa + ptdca <==> amp + ppi + ptdcacoa R_FACOAL204i subsystem: Fatty acid activation R_FACOAL204i equation: [c] : arachd + atp + coa --> amp + arachdcoa + ppi R_FACOAL170 subsystem: Fatty acid activation R_FACOAL170 equation: [c] : atp + coa + hpdca <==> amp + hpdcacoa + ppi
modifier: 634199
modifier: 634247
modifier: 634175
product: 634151
is: http://identifiers.org/ec-code/6.2.1.3
product: 634127
modifier: 634223
product: 634139
reversible: false
modifier: 634187
reactant: 634091

590041
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: AMP_C10H12N5O7P

634115
type: SpeciesReference
stoichiometry: 1.0
species: 590727

634103
type: SpeciesReference
stoichiometry: 1.0
species: 590439

590439
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: arachidonic acid_C20H31O2

608455
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: pentadecanoate_C15H29O2

600188
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: heptadecanoate_C17H33O2

634151
type: SpeciesReference
stoichiometry: 1.0
species: 607728

634127
type: SpeciesReference
stoichiometry: 1.0
species: 590475

590475
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: C20:4-CoA_C41H62N7O17P3S

634139
type: SpeciesReference
stoichiometry: 1.0
species: 590041

608468
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: pentadecanoyl Coenzyme A_C36H60N7O17P3S

634091
type: SpeciesReference
stoichiometry: 1.0
species: 592342

590235
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: alpha-Pinene-oxide_C10H16O

595498
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: dTTP_C10H13N2O14P3

016576
type: Reaction
reactant: 688480
product: 688576
product: 688528
reactant: 688492
product: 688588
product: 688552
is: ENSECAG00000015291.1
reactant: 688516
reactant: 688468
product: 688564
product: 688540
notes: R_CHOLATEt3 subsystem: Transport, Extracellular R_CHOLATEt3 equation: atp[c] + cholate[c] + h2o[c] --> adp[c] + cholate[e] + h[c] + pi[c] R_TCHOLAt3 subsystem: Transport, Extracellular R_TCHOLAt3 equation: atp[c] + h2o[c] + tchola[c] --> adp[c] + h[c] + pi[c] + tchola[e] R_GCHOLAt3 subsystem: Transport, Extracellular R_GCHOLAt3 equation: atp[c] + gchola[c] + h2o[c] --> adp[c] + gchola[e] + h[c] + pi[c]
reversible: false
reactant: 688504
fast: false

688480
type: SpeciesReference
stoichiometry: 1.0
species: 610115

688576
type: SpeciesReference
stoichiometry: 1.0
species: 591712

688528
type: SpeciesReference
stoichiometry: 1.0
species: 610127

688492
type: SpeciesReference
stoichiometry: 1.0
species: 597795

688588
type: SpeciesReference
stoichiometry: 3.0
species: 599531

688552
type: SpeciesReference
stoichiometry: 1.0
species: 597808

688516
type: SpeciesReference
stoichiometry: 3.0
species: 599421

688468
type: SpeciesReference
stoichiometry: 3.0
species: 590727

688564
type: SpeciesReference
stoichiometry: 3.0
species: 589206

688540
type: SpeciesReference
stoichiometry: 3.0
species: 607462

688504
type: SpeciesReference
stoichiometry: 1.0
species: 591700

587815
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: R total 2 position_CO2FULLR2

604633
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: mannosyl-glucosaminyl-acylphosphatidylinositiol (H2)_C37H68NO19PFULLRCO2FULLR2CO2

014526
type: Reaction
reversible: true
fast: false
reactant: 667830
reactant: 667818
product: 667866
reactant: 667806
product: 667842
is: ENSECAG00000007684.1
notes: R_GAMt1r subsystem: Transport, Extracellular R_GAMt1r equation: gam[e] <==> gam[c] R_GLCt1r subsystem: Transport, Extracellular R_GLCt1r equation: glc-D[e] <==> glc-D[c] R_DHAAt1r subsystem: Transport, Extracellular R_DHAAt1r equation: dhdascb[e] <==> dhdascb[c]
product: 667854

667830
type: SpeciesReference
stoichiometry: 1.0
species: 597723

597723
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: D-Glucosamine_C6H14NO5

667818
type: SpeciesReference
stoichiometry: 1.0
species: 594540

594540
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Dehydroascorbate_C6H6O6

667866
type: SpeciesReference
stoichiometry: 1.0
species: 598097

598097
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Glucose_C6H12O6

667806
type: SpeciesReference
stoichiometry: 1.0
species: 598109

598109
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: D-Glucose_C6H12O6

667842
type: SpeciesReference
stoichiometry: 1.0
species: 594528

594528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dehydroascorbate_C6H6O6

667854
type: SpeciesReference
stoichiometry: 1.0
species: 597710

597710
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Glucosamine_C6H14NO5

011414
type: Reaction
notes: R_GAO1g subsystem: Sphingolipid Metabolism R_GAO1g equation: [g] : accoa + gd3_hs --> coa + oagd3_hs R_ACCOAgt subsystem: Transport, Extracellular R_ACCOAgt equation: accoa[c] <==> accoa[g] R_GAO2g subsystem: Sphingolipid Metabolism R_GAO2g equation: [g] : accoa + gt3_hs --> coa + oagt3_hs R_GAO1 subsystem: Sphingolipid Metabolism R_GAO1 equation: [c] : accoa + gd3_hs --> coa + oagd3_hs R_GAO2 subsystem: Sphingolipid Metabolism R_GAO2 equation: [c] : accoa + gt3_hs --> coa + oagt3_hs R_ACODA subsystem: Urea cycle/amino group metabolism R_ACODA equation: [c] : acorn + h2o --> ac + orn R_ACCOAtr subsystem: Transport, Endoplasmic Reticular R_ACCOAtr equation: accoa[c] <==> accoa[r]
modifier: 638128
reactant: 637924
product: 638080
is: http://identifiers.org/ec-code/3.5.1.16
reactant: 637960
product: 638068
product: 638056
reversible: false
product: 638008
reactant: 637936
fast: false
reactant: 637996
modifier: 638116
modifier: 638104
product: 638092
reactant: 637972
reactant: 637984
product: 638044
is: ENSECAG00000022461.1
product: 638032
reactant: 637912
reactant: 637948
product: 638020

637924
type: SpeciesReference
stoichiometry: 1.0
species: 599144

599144
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GT3 (homo sapiens)_C63H104N4O36FULLRCO

638080
type: SpeciesReference
stoichiometry: 1.0
species: 606467

637960
type: SpeciesReference
stoichiometry: 1.0
species: 597904

597904
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: GD3 (homo sapiens)_C52H88N3O28FULLRCO

638068
type: SpeciesReference
stoichiometry: 1.0
species: 606167

606167
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: _9-O-Acetylated GT3 (homo sapiens)_C65H106N4O37FULLRCO

638056
type: SpeciesReference
stoichiometry: 1.0
species: 606143

606143
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: _9-O-Acetylated GD3 (homo sapiens)_C54H90N3O29FULLRCO

638008
type: SpeciesReference
stoichiometry: 2.0
species: 592354

592354
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Coenzyme A_C21H32N7O16P3S

637936
type: SpeciesReference
stoichiometry: 1.0
species: 589025

589025
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N2-Acetyl-L-ornithine_C7H14N2O3

637996
type: SpeciesReference
stoichiometry: 1.0
species: 597916

597916
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GD3 (homo sapiens)_C52H88N3O28FULLRCO

588420
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Acetyl-CoA_C23H34N7O17P3S

638092
type: SpeciesReference
stoichiometry: 1.0
species: 606155

606155
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _9-O-Acetylated GT3 (homo sapiens)_C65H106N4O37FULLRCO

637972
type: SpeciesReference
stoichiometry: 2.0
species: 588408

637984
type: SpeciesReference
stoichiometry: 1.0
species: 599421

638044
type: SpeciesReference
stoichiometry: 1.0
species: 588264

588264
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Acetate_C2H3O2

638032
type: SpeciesReference
stoichiometry: 1.0
species: 606130

606130
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _9-O-Acetylated GD3 (homo sapiens)_C54H90N3O29FULLRCO

637912
type: SpeciesReference
stoichiometry: 2.0
species: 588420

637948
type: SpeciesReference
stoichiometry: 1.0
species: 599132

599132
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: GT3 (homo sapiens)_C63H104N4O36FULLRCO

638020
type: SpeciesReference
stoichiometry: 2.0
species: 592342

608944
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Riboflavin_C17H20N4O6

010049
type: Reaction
modifier: 626608
product: 626344
notes: R_GCCbim subsystem: Glycine, Serine, and Threonine Metabolism R_GCCbim equation: [m] : alpro + thf --> dhlpro + mlthf + nh4 R_PDHm subsystem: Glycolysis/Gluconeogenesis R_PDHm equation: [m] : coa + nad + pyr --> accoa + co2 + nadh R_OIVD2m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD2m equation: [m] : 3mob + coa + nad --> co2 + ibcoa + nadh R_2OXOADOXm subsystem: Lysine Metabolism R_2OXOADOXm equation: [m] : 2oxoadp + coa + nad --> co2 + glutcoa + nadh R_GCCcm subsystem: Glycine, Serine, and Threonine Metabolism R_GCCcm equation: [m] : dhlpro + nad <==> h + lpro + nadh R_GCC2bim subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2bim equation: [m] : alpam + thf --> dhlam + mlthf + nh4 R_OIVD3m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD3m equation: [m] : 3mop + coa + nad --> 2mbcoa + co2 + nadh R_GCCam subsystem: Glycine, Serine, and Threonine Metabolism R_GCCam equation: [m] : gly + h + lpro <==> alpro + co2 R_GCC2cm subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2cm equation: [m] : dhlam + nad <==> h + lpam + nadh R_OIVD1m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD1m equation: [m] : 4mop + coa + nad --> co2 + ivcoa + nadh R_GCC2am subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2am equation: [m] : gly + h + lpam <==> alpam + co2 R_AKGDm subsystem: Citric Acid Cycle R_AKGDm equation: [m] : akg + coa + nad --> co2 + nadh + succoa
modifier: 626524
product: 626356
fast: false
reactant: 626260
reactant: 626332
reactant: 626212
modifier: 626584
modifier: 626572
product: 626428
is: ENSECAG00000000749.1
reactant: 626296
product: 626440
is: http://identifiers.org/ec-code/1.4.4.2
product: 626452
reactant: 626248
modifier: 626512
reactant: 626320
is: http://identifiers.org/ec-code/1.8.1.4
reactant: 626308
reactant: 626284
reversible: false
modifier: 626548
product: 626380
modifier: 626560
modifier: 626536
is: http://identifiers.org/ec-code/2.1.2.10
reactant: 626236
product: 626392
product: 626464
reactant: 626224
product: 626476
is: http://identifiers.org/ec-code/1.2.1.25
modifier: 626488
modifier: 626500
modifier: 626596
product: 626368
product: 626404
is: http://identifiers.org/ec-code/1.2.4.2
is: http://identifiers.org/ec-code/1.2.4.1
reactant: 626272
product: 626416

626344
type: SpeciesReference
stoichiometry: 1.0
species: 609957

609957
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Succinyl-CoA_C25H35N7O19P3S

594672
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Dihydrolipolprotein_H2S2X

626356
type: SpeciesReference
stoichiometry: 1.0
species: 601335

601335
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Isovaleryl-CoA_C26H40N7O17P3S

626260
type: SpeciesReference
stoichiometry: 1.0
species: 585902

585902
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _3-Methyl-2-oxobutanoate_C5H7O3

626332
type: SpeciesReference
stoichiometry: 6.0
species: 605272

626212
type: SpeciesReference
stoichiometry: 1.0
species: 585319

589944
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: S-aminomethyldihydrolipoamide_C9H21N2OS2

626428
type: SpeciesReference
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species: 588432

626296
type: SpeciesReference
stoichiometry: 2.0
species: 610644

610644
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _5,6,7,8-Tetrahydrofolate_C19H21N7O6

626440
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species: 594660

594660
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Dihydrolipoamide_C8H17NOS2

626452
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stoichiometry: 1.0
species: 600888

600888
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Isobutyryl-CoA_C25H38N7O17P3S

626248
type: SpeciesReference
stoichiometry: 1.0
species: 589956

589956
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: S-Aminomethyldihydrolipoylprotein_CH6NS2X

626320
type: SpeciesReference
stoichiometry: 1.0
species: 585926

626308
type: SpeciesReference
stoichiometry: 1.0
species: 608665

626284
type: SpeciesReference
stoichiometry: 1.0
species: 589712

603590
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Lipoamide_C8H15NOS2

626380
type: SpeciesReference
stoichiometry: 6.0
species: 592294

603626
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Lipoylprotein_S2X

626236
type: SpeciesReference
stoichiometry: 1.0
species: 589944

626392
type: SpeciesReference
stoichiometry: 1.0
species: 598398

598398
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Glutaryl-CoA_C26H37N7O19P3S

626464
type: SpeciesReference
stoichiometry: 2.0
species: 604886

604886
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _5,10-Methylenetetrahydrofolate_C20H21N7O6

626224
type: SpeciesReference
stoichiometry: 1.0
species: 586496

586496
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _4-Methyl-2-oxopentanoate_C6H9O3

626476
type: SpeciesReference
stoichiometry: 6.0
species: 605334

598482
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Glycine_C2H5NO2

626368
type: SpeciesReference
stoichiometry: 1.0
species: 585259

585259
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _2-Methylbutanoyl-CoA_C26H40N7O17P3S

626404
type: SpeciesReference
stoichiometry: 1.0
species: 594672

626272
type: SpeciesReference
stoichiometry: 6.0
species: 592378

626416
type: SpeciesReference
stoichiometry: 2.0
species: 605587

012499
type: Reaction
reactant: 648006
is: ENSECAG00000018632.1
product: 648042
reactant: 647981
notes: R_UREAt subsystem: Transport, Extracellular R_UREAt equation: urea[e] <==> urea[c] R_NAIt subsystem: Transport, Extracellular R_NAIt equation: i[e] + (2) na1[e] <==> i[c] + (2) na1[c] R_NAt subsystem: Transport, Extracellular R_NAt equation: na1[e] <==> na1[c]
product: 648018
reactant: 647994
reversible: true
fast: false
product: 648030

648006
type: SpeciesReference
stoichiometry: 1.0
species: 611817

611817
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Urea_CH4N2O

648042
type: SpeciesReference
stoichiometry: 1.0
species: 611805

611805
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Urea_CH4N2O

647981
type: SpeciesReference
stoichiometry: 3.0
species: 605200

648018
type: SpeciesReference
stoichiometry: 3.0
species: 605187

647994
type: SpeciesReference
stoichiometry: 1.0
species: 600876

600876
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Iodide_I

648030
type: SpeciesReference
stoichiometry: 1.0
species: 600864

600864
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Iodide_I

010254
type: Reaction
is: ENSECAG00000020669.1
fast: false
product: 628150
notes: R_LDH_L subsystem: Glycolysis/Gluconeogenesis R_LDH_L equation: [c] : lac-L + nad <==> h + nadh + pyr R_MCLOR subsystem: Cysteine Metabolism R_MCLOR equation: [c] : mercplac + nad <==> h + mercppyr + nadh R_HPYRR2x subsystem: Glyoxylate and Dicarboxylate Metabolism R_HPYRR2x equation: [c] : h + hpyr + nadh --> glyc-S + nad R_2HBO subsystem: Propanoate Metabolism R_2HBO equation: [c] : 2hb + nad <==> 2obut + h + nadh R_LDH_Lm subsystem: Pyruvate Metabolism R_LDH_Lm equation: [m] : lac-L + nad <==> h + nadh + pyr R_GLXO1 subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO1 equation: [c] : glx + h2o + nad --> (2) h + nadh + oxa R_CREATt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_CREATt4_LPAREN_2_RPAREN_r equation: creat[e] + (2) na1[e] <==> creat[c] + (2) na1[c]
product: 628126
reactant: 628054
product: 628114
reactant: 628090
is: http://identifiers.org/ec-code/1.2.3.5
modifier: 628284
modifier: 628234
reactant: 628066
reactant: 628041
reversible: false
modifier: 628368
modifier: 628308
modifier: 628246
modifier: 628186
modifier: 628344
is: http://identifiers.org/ec-code/1.1.1.27
modifier: 628198
reactant: 628078
product: 628138
reactant: 628102
modifier: 628356
modifier: 628296
modifier: 628210
modifier: 628259
modifier: 628222
modifier: 628380
modifier: 628320
modifier: 628174
modifier: 628332
modifier: 628272
product: 628162

628150
type: SpeciesReference
stoichiometry: 2.0
species: 599531

628126
type: SpeciesReference
stoichiometry: 1.0
species: 605248

628054
type: SpeciesReference
stoichiometry: 1.0
species: 600249

628114
type: SpeciesReference
stoichiometry: 1.0
species: 606528

606528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Oxalate_C2O4

628090
type: SpeciesReference
stoichiometry: 1.0
species: 599531

592547
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Creatine_C4H9N3O2

604511
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Mercaptopyruvate_C3H3O3S

628066
type: SpeciesReference
stoichiometry: 1.0
species: 598410

598410
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Glyoxylate_C2H1O3

628041
type: SpeciesReference
stoichiometry: 1.0
species: 605248

602904
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Lactate_C3H5O3

592535
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Creatine_C4H9N3O2

585199
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _2-Hydroxybutyrate_C4H7O3

628078
type: SpeciesReference
stoichiometry: 1.0
species: 599421

628138
type: SpeciesReference
stoichiometry: 1.0
species: 598578

598578
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: (S)-Glycerate_C3H5O4

628102
type: SpeciesReference
stoichiometry: 1.0
species: 605322

602928
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Lactate_C3H5O3

585295
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _2-Oxobutanoate_C4H5O3

608640
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Pyruvate_C3H3O3

628162
type: SpeciesReference
stoichiometry: 1.0
species: 605322

593390
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S) proteoglycan_C45H65N2O48S4X

010978
type: Reaction
is: http://identifiers.org/ec-code/2.6.1.7
product: 635054
reactant: 635018
product: 635030
product: 635042
reactant: 635006
reactant: 634994
is: ENSECAG00000022067.1
reversible: false
notes: R_3HKYNAKGAT subsystem: Tryptophan metabolism R_3HKYNAKGAT equation: [c] : akg + hLkynr --> 42A3HP24DB + glu-L R_KYNAKGAT subsystem: Tryptophan metabolism R_KYNAKGAT equation: [c] : Lkynr + akg --> 4aphdob + glu-L
fast: false

635054
type: SpeciesReference
stoichiometry: 1.0
species: 586168

586168
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate_C10H8NO5

635018
type: SpeciesReference
stoichiometry: 1.0
species: 587659

587659
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Kynurenine_C10H12N2O3

635030
type: SpeciesReference
stoichiometry: 1.0
species: 586327

586327
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _4-(2-Aminophenyl)-2,4-dioxobutanoate_C10H8NO4

635042
type: SpeciesReference
stoichiometry: 2.0
species: 598265

635006
type: SpeciesReference
stoichiometry: 1.0
species: 599519

599519
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Hydroxy-L-kynurenine_C10H12N2O4

634994
type: SpeciesReference
stoichiometry: 2.0
species: 589688

587357
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: hexaglutamyl folate (THF)_C44H51N12O21

589134
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: acyl-dihydroxyacetone phosphate_C3H4O6PFULLRCO

593766
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: dATP_C10H12N5O12P3

604994
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol, human uterine homolog_C1245H2040N20O220P20

598133
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: D-Glucose_C6H12O6

589459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Adrenaline_C9H14NO3

588857
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-Acetyl-D-mannosamine_C8H15NO6

009137
type: Reaction
reactant: 617811
is: http://identifiers.org/ec-code/2.6.1.3
notes: R_EHGLAT subsystem: Arginine and Proline Metabolism R_EHGLAT equation: [c] : akg + e4hglu --> 4h2oglt + glu-L R_LCYSTAT subsystem: Cysteine Metabolism R_LCYSTAT equation: [c] : Lcyst + akg <==> 3spyr + glu-L R_CYSTA subsystem: Cysteine Metabolism R_CYSTA equation: [c] : akg + cys-L <==> glu-L + mercppyr R_ASPTA subsystem: Alanine and Aspartate Metabolism R_ASPTA equation: [c] : akg + asp-L <==> glu-L + oaa R_3SALATAi subsystem: Cysteine Metabolism R_3SALATAi equation: [c] : 3sala + akg + h --> 3snpyr + glu-L R_TYRTA subsystem: Tyrosine metabolism R_TYRTA equation: [c] : akg + tyr-L <==> 34hpp + glu-L R_PHETA1 subsystem: Phenylalanine metabolism R_PHETA1 equation: [c] : akg + phe-L <==> glu-L + phpyr
modifier: 617969
modifier: 617932
reactant: 617835
is: http://identifiers.org/ec-code/2.6.1.5
modifier: 617945
modifier: 618005
modifier: 617896
product: 617884
modifier: 617981
modifier: 617993
modifier: 617957
fast: false
reactant: 617847
reactant: 617823
modifier: 617908
modifier: 618030
product: 617859
modifier: 618018
is: http://identifiers.org/ec-code/2.6.1.1
product: 617871
is: http://identifiers.org/ec-code/2.6.1.58
reversible: false
is: ENSECAG00000000095.1
modifier: 617920

617811
type: SpeciesReference
stoichiometry: 2.0
species: 589688

587599
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Cysteate_C3H6NO5S

617835
type: SpeciesReference
stoichiometry: 1.0
species: 599531

606094
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Oxaloacetate_C4H2O5

611333
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Tyrosine_C9H11NO3

590691
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Aspartate_C4H6NO4

617884
type: SpeciesReference
stoichiometry: 1.0
species: 586107

586107
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Sulfinopyruvate_C3H2O5S

585451
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-(4-Hydroxyphenyl)pyruvate_C9H7O4

593500
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Cysteine_C3H7NO2S

607376
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Phenylpyruvate_C9H7O3

617847
type: SpeciesReference
stoichiometry: 1.0
species: 586082

586082
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Sulfino-L-alanine_C3H5NO4S

617823
type: SpeciesReference
stoichiometry: 1.0
species: 595690

595690
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-erythro-4-Hydroxyglutamate_C5H8NO5

617859
type: SpeciesReference
stoichiometry: 2.0
species: 598265

617871
type: SpeciesReference
stoichiometry: 1.0
species: 586351

586351
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _4-Hydroxy-2-oxoglutarate_C5H4O6

586131
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Sulfopyruvate_C3H2O6S

592135
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341

599617
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: H+_H

591652
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Choline_C5H14NO

014827
type: Reaction
reactant: 669943
product: 670033
product: 670008
product: 670045
reactant: 669995
reactant: 669956
is: ENSECAG00000019369.1
reversible: false
reactant: 669982
reactant: 669969
notes: R_24_COMMA_25VITD3Hm subsystem: Vitamin D R_24_COMMA_25VITD3Hm equation: [m] : 25hvitd3 + h + nadph + o2 --> 2425dhvitd3 + h2o + nadp R_24_COMMA_25VITD2Hm subsystem: Vitamin D R_24_COMMA_25VITD2Hm equation: [m] : 25hvitd2 + h + nadph + o2 --> 2425dhvitd2 + h2o + nadp
fast: false
product: 670021

669943
type: SpeciesReference
stoichiometry: 1.0
species: 585041

585041
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _25-Hydroxyvitamin D2_C28H44O2

670033
type: SpeciesReference
stoichiometry: 1.0
species: 585005

585005
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _24R,25-Dihydroxyvitamin D3_C27H44O3

670008
type: SpeciesReference
stoichiometry: 2.0
species: 599469

670045
type: SpeciesReference
stoichiometry: 2.0
species: 605394

669995
type: SpeciesReference
stoichiometry: 2.0
species: 599581

669956
type: SpeciesReference
stoichiometry: 1.0
species: 585053

585053
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _25-Hydroxyvitamin D3_C27H44O2

669982
type: SpeciesReference
stoichiometry: 2.0
species: 605984

605984
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: O2_O2

669969
type: SpeciesReference
stoichiometry: 2.0
species: 605454

670021
type: SpeciesReference
stoichiometry: 1.0
species: 584992

584992
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _24R,25-Dihyoxyvitamin D2_C28H44O3

011715
type: Reaction
product: 640755
reactant: 640695
fast: false
product: 640743
reactant: 640719
reactant: 640707
reversible: false
is: http://identifiers.org/ec-code/4.1.1.15
notes: R_3SALACBOXL subsystem: Taurine and hypotaurine metabolism R_3SALACBOXL equation: [c] : 3sala + h --> co2 + hyptaur R_GLUDC subsystem: Glutamate metabolism R_GLUDC equation: [c] : glu-L + h --> 4abut + co2 R_LCYSTCBOXL subsystem: Taurine and hypotaurine metabolism R_LCYSTCBOXL equation: [c] : Lcyst + h --> co2 + taur
reactant: 640682
product: 640731
is: ENSECAG00000009017.1
is: ENSECAG00000000006.1
product: 640767

640755
type: SpeciesReference
stoichiometry: 1.0
species: 600852

600852
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Hypotaurine_C2H6NO2S

640695
type: SpeciesReference
stoichiometry: 1.0
species: 586082

640743
type: SpeciesReference
stoichiometry: 1.0
species: 586265

586265
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _4-Aminobutanoate_C4H9NO2

640719
type: SpeciesReference
stoichiometry: 3.0
species: 599531

640707
type: SpeciesReference
stoichiometry: 1.0
species: 598265

640682
type: SpeciesReference
stoichiometry: 1.0
species: 587599

640731
type: SpeciesReference
stoichiometry: 1.0
species: 610067

610067
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Taurine_C2H7NO3S

640767
type: SpeciesReference
stoichiometry: 3.0
species: 592269

598590
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Glycerol_C3H8O3

011523
type: Reaction
fast: false
reversible: false
product: 639347
name: _5,10-methylenetetrahydrofolatereductase (NADPH)
is: http://identifiers.org/ec-code/1.5.1.20
reactant: 639323
notes: R_MTHFR3 subsystem: Folate Metabolism R_MTHFR3 equation: [c] : (2) h + mlthf + nadph --> 5mthf + nadp
reactant: 639299
reactant: 639311
is: ENSECAG00000020032.1
product: 639335

639347
type: SpeciesReference
stoichiometry: 1.0
species: 587104

639323
type: SpeciesReference
stoichiometry: 1.0
species: 605442

639299
type: SpeciesReference
stoichiometry: 1.0
species: 604874

604874
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5,10-Methylenetetrahydrofolate_C20H21N7O6

639311
type: SpeciesReference
stoichiometry: 2.0
species: 599531

639335
type: SpeciesReference
stoichiometry: 1.0
species: 605370

011160
type: Reaction
fast: false
product: 636477
reversible: true
is: ENSECAG00000008304.1
product: 636501
reactant: 636465
reactant: 636441
reactant: 636453
notes: R_CITt4_2 subsystem: Transport, Extracellular R_CITt4_2 equation: cit[e] + (2) na1[e] <==> cit[c] + (2) na1[c] R_SUCCt4_2 subsystem: Transport, Extracellular R_SUCCt4_2 equation: (2) na1[e] + succ[e] <==> (2) na1[c] + succ[c]
product: 636489

636477
type: SpeciesReference
stoichiometry: 1.0
species: 609896

636501
type: SpeciesReference
stoichiometry: 1.0
species: 591965

636465
type: SpeciesReference
stoichiometry: 1.0
species: 591977

591977
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Citrate_C6H5O7

636441
type: SpeciesReference
stoichiometry: 4.0
species: 605200

636453
type: SpeciesReference
stoichiometry: 1.0
species: 609908

636489
type: SpeciesReference
stoichiometry: 4.0
species: 605187

608198
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: (13E)-11alpha-Hydroxy-9,15-dioxoprost-13-enoate_C20H31O5

610487
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Tetrahydrobiopterin-4a-carbinolamine_C9H15N5O4

596200
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Ethanolamine phosphate_C2H7NO4P

016498
type: Reaction
reactant: 688006
product: 688092
is: ENSECAG00000009420.1
reactant: 688019
product: 688068
notes: R_NTD7e subsystem: Nucleotides R_NTD7e equation: [e] : amp + h2o --> adn + pi R_NTD2e subsystem: Nucleotides R_NTD2e equation: [e] : h2o + ump --> pi + uri R_NTD9e subsystem: Nucleotides R_NTD9e equation: [e] : gmp + h2o --> gsn + pi R_NTD4e subsystem: Nucleotides R_NTD4e equation: [e] : cmp + h2o --> cytd + pi
reactant: 688031
product: 688080
is: http://identifiers.org/ec-code/3.1.3.5
reversible: false
reactant: 687994
product: 688055
reactant: 688043
product: 688104
fast: false

688006
type: SpeciesReference
stoichiometry: 1.0
species: 592160

592160
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: CMP_C9H12N3O8P

688092
type: SpeciesReference
stoichiometry: 1.0
species: 589158

589158
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Adenosine_C10H13N5O4

688019
type: SpeciesReference
stoichiometry: 1.0
species: 590053

688068
type: SpeciesReference
stoichiometry: 4.0
species: 607474

607474
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Phosphate_HO4P

688031
type: SpeciesReference
stoichiometry: 4.0
species: 599433

599433
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: H2O_H2O

688080
type: SpeciesReference
stoichiometry: 1.0
species: 593572

593572
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Cytidine_C9H13N3O5

687994
type: SpeciesReference
stoichiometry: 1.0
species: 598820

598820
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: GMP_C10H12N5O8P

688055
type: SpeciesReference
stoichiometry: 1.0
species: 611853

611853
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Uridine_C9H12N2O6

688043
type: SpeciesReference
stoichiometry: 1.0
species: 611672

611672
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: UMP_C9H11N2O9P

688104
type: SpeciesReference
stoichiometry: 1.0
species: 599036

599036
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Guanosine_C10H13N5O5

589884
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: L-Alanine_C3H7NO2

590967
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Bilirubin_C33H34N4O6

013730
type: Reaction
reactant: 660478
is: http://identifiers.org/ec-code/2.8.3.5
product: 660490
name: _3-oxoacid CoA-transferase
is: ENSECAG00000018312.1
product: 660502
fast: false
reactant: 660466
notes: R_OCOAT1m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OCOAT1m equation: [m] : acac + succoa <==> aacoa + succ
reversible: true

660478
type: SpeciesReference
stoichiometry: 1.0
species: 588336

588336
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Acetoacetate_C4H5O3

660490
type: SpeciesReference
stoichiometry: 1.0
species: 588203

660502
type: SpeciesReference
stoichiometry: 1.0
species: 609921

609921
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Succinate_C4H4O4

660466
type: SpeciesReference
stoichiometry: 1.0
species: 609957

596696
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine_C8H15N3O8P

592099
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: clupanodonyl CoA_C43H64N7O17P3S

600575
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: heparan sulfate, free chain_C79H114N5O102S12

607873
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Inorganic triphosphate_HO10P3

594227
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: dGDP_C10H12N5O10P2

016964
type: Reaction
is: ENSECAG00000011464.1
reversible: false
reactant: 691363
product: 691375
name: Lactosylceramide alpha-2,3-sialyltransferase, Golgi apparatus
fast: false
is: http://identifiers.org/ec-code/2.4.99.9
product: 691399
notes: R_SIAT9g subsystem: Sphingolipid Metabolism R_SIAT9g equation: [g] : cmpacna + galgluside_hs --> cmp + gm3_hs + h
product: 691387
reactant: 691351

691363
type: SpeciesReference
stoichiometry: 1.0
species: 597626

597626
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: galactosyl glucosyl ceramide_C30H56NO12FULLRCO

691375
type: SpeciesReference
stoichiometry: 1.0
species: 599556

691399
type: SpeciesReference
stoichiometry: 1.0
species: 598796

598796
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: ganglioside GM3 (homo sapiens)_C41H72N2O20FULLRCO

691387
type: SpeciesReference
stoichiometry: 1.0
species: 592172

592172
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: CMP_C9H12N3O8P

691351
type: SpeciesReference
stoichiometry: 1.0
species: 592220

592220
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: CMP-N-acetylneuraminate_C20H29N4O16P

596781
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Type IIH glycolipid_C50H89N2O26FULLRCO

018214
type: Reaction
product: 702857
reactant: 702844
notes: R_COAtm subsystem: Transport, Mitochondrial R_COAtm equation: coa[c] <==> coa[m]
is: ENSECAG00000010181.1
fast: false
reversible: true
name: CoA transporter

702857
type: SpeciesReference
stoichiometry: 1.0
species: 592378

702844
type: SpeciesReference
stoichiometry: 1.0
species: 592342

606251
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: octadecenoate (n-C18:1)_C18H33O2

607546
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Phosphate_HO4P

584750
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _13-cis-retinoate_C20H27O2

013187
type: Reaction
product: 653656
is: ENSECAG00000022042.1
is: http://identifiers.org/ec-code/2.4.2.1
modifier: 653897
modifier: 653704
is: ENSECAG00000017655.1
notes: R_PUNP5 subsystem: Purine Catabolism R_PUNP5 equation: [c] : ins + pi <==> hxan + r1p R_PUNP3 subsystem: Purine Catabolism R_PUNP3 equation: [c] : gsn + pi <==> gua + r1p R_PUNP4 subsystem: Purine Catabolism R_PUNP4 equation: [c] : dgsn + pi <==> 2dr1p + gua R_PUNP2 subsystem: Purine Catabolism R_PUNP2 equation: [c] : dad-2 + pi <==> 2dr1p + ade R_PUNP1 subsystem: Nucleotides R_PUNP1 equation: [c] : adn + pi <==> ade + r1p R_PUNP7 subsystem: Nucleotides R_PUNP7 equation: [c] : pi + xtsn <==> r1p + xan R_PUNP6 subsystem: Purine Catabolism R_PUNP6 equation: [c] : din + pi <==> 2dr1p + hxan R_DURIPP subsystem: Nucleotides R_DURIPP equation: [c] : duri + pi <==> 2dr1p + ura R_PNP subsystem: NAD Metabolism R_PNP equation: [c] : pi + rnam <==> h + ncam + r1p R_NP1 subsystem: NAD Metabolism R_NP1 equation: [c] : h + nac + r1p --> nicrns + pi
modifier: 653764
modifier: 653861
is: ENSECAG00000003847.1
modifier: 653680
modifier: 653728
reactant: 653644
modifier: 653788
modifier: 653752
modifier: 653848
modifier: 653824
modifier: 653885
modifier: 653800
is: ENSECAG00000019585.1
fast: false
modifier: 653716
reversible: false
reactant: 653620
modifier: 653776
modifier: 653692
modifier: 653873
product: 653668
reactant: 653632
modifier: 653740
modifier: 653836
modifier: 653812

653656
type: SpeciesReference
stoichiometry: 1.0
species: 607462

600791
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Hypoxanthine_C5H4N4O

605527
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Nicotinamide_C6H6N2O

595606
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Deoxyuridine_C9H12N2O5

594794
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Deoxyinosine_C10H12N4O4

653644
type: SpeciesReference
stoichiometry: 1.0
species: 599531

612131
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Xanthine_C5H4N4O2

601190
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Inosine_C10H12N4O5

608956
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-Ribosylnicotinamide_C11H15N2O5

594312
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Deoxyguanosine_C10H13N5O4

589086
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Adenine_C5H5N5

612500
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Xanthosine_C10H12N4O6

653620
type: SpeciesReference
stoichiometry: 1.0
species: 608750

608750
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: alpha-D-Ribose 1-phosphate_C5H9O8P

599288
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Guanine_C5H5N5O

611757
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Uracil_C4H4N2O2

653668
type: SpeciesReference
stoichiometry: 1.0
species: 605635

605635
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Nicotinate D-ribonucleoside_C11H13NO6

653632
type: SpeciesReference
stoichiometry: 1.0
species: 605236

585174
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _2-Deoxy-D-ribose 1-phosphate_C5H9O7P

589146
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Adenosine_C10H13N5O4

599024
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Guanosine_C10H13N5O5

018106
type: Reaction
is: ENSECAG00000015427.1
reactant: 702244
reversible: false
name: porphobilinogen synthase
fast: false
is: http://identifiers.org/ec-code/4.2.1.24
product: 702268
product: 702280
notes: R_PPBNGS subsystem: Heme Biosynthesis R_PPBNGS equation: [c] : (2) 5aop --> h + (2) h2o + ppbng
product: 702256

702244
type: SpeciesReference
stoichiometry: 2.0
species: 586808

586808
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5-Amino-4-oxopentanoate_C5H9NO3

702268
type: SpeciesReference
stoichiometry: 2.0
species: 599421

702280
type: SpeciesReference
stoichiometry: 1.0
species: 599531

702256
type: SpeciesReference
stoichiometry: 1.0
species: 607679

594964
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S

597432
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: D-Galactose_C6H12O6

019031
type: Reaction
product: 712769
reactant: 712745
product: 712757
reactant: 712721
is: http://identifiers.org/ec-code/3.1.4.17
reversible: false
notes: R_PDE1 subsystem: Nucleotides R_PDE1 equation: [c] : camp + h2o --> amp + h R_PSP_L subsystem: Glycine, Serine, and Threonine Metabolism R_PSP_L equation: [c] : h2o + pser-L --> pi + ser-L
product: 712793
is: ENSECAG00000011003.1
is: http://identifiers.org/ec-code/3.1.3.3
product: 712781
reactant: 712733
fast: false

712769
type: SpeciesReference
stoichiometry: 1.0
species: 607462

712745
type: SpeciesReference
stoichiometry: 2.0
species: 599421

712757
type: SpeciesReference
stoichiometry: 1.0
species: 609352

712721
type: SpeciesReference
stoichiometry: 1.0
species: 591320

591320
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: cAMP_C10H11N5O6P

712793
type: SpeciesReference
stoichiometry: 1.0
species: 599531

712781
type: SpeciesReference
stoichiometry: 1.0
species: 590041

712733
type: SpeciesReference
stoichiometry: 1.0
species: 608441

596053
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _16-Glucuronide-estriol_C24H32O9

602868
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Lactate_C3H5O3

599228
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Reduced glutathione_C10H16N3O6S

594916
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: demethylated antipyrine_C10H10N2O

596480
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Fe2+_Fe

017457
type: Reaction
fast: false
product: 696902
notes: R_UDPXYLtg subsystem: Transport, Golgi Apparatus R_UDPXYLtg equation: udpxyl[c] + ump[g] <==> udpxyl[g] + ump[c] R_UDPGLCtg subsystem: Transport, Golgi Apparatus R_UDPGLCtg equation: udpg[c] + ump[g] <==> udpg[g] + ump[c]
reactant: 696854
product: 696890
reversible: true
reactant: 696842
product: 696878
is: ENSECAG00000012567.1
reactant: 696866

696902
type: SpeciesReference
stoichiometry: 1.0
species: 611537

611537
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: UDPglucose_C15H22N2O17P2

696854
type: SpeciesReference
stoichiometry: 1.0
species: 611622

611622
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: UDP-D-xylose_C14H20N2O16P2

696890
type: SpeciesReference
stoichiometry: 2.0
species: 611660

696842
type: SpeciesReference
stoichiometry: 1.0
species: 611525

696878
type: SpeciesReference
stoichiometry: 1.0
species: 611635

611635
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: UDP-D-xylose_C14H20N2O16P2

696866
type: SpeciesReference
stoichiometry: 2.0
species: 611684

584918
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _1-Methylpyrrolinium_C5H10N

601467
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 16_C160H258N11O137S7

010905
type: Reaction
reactant: 634416
reactant: 634428
product: 634560
reactant: 634440
product: 634500
product: 634536
is: ENSECAG00000022646.1
reactant: 634452
reactant: 634488
reversible: false
product: 634512
reactant: 634464
notes: R_GLCAASE1ly subsystem: Heparan sulfate degradation R_GLCAASE1ly equation: [l] : h2o + hs_deg9 --> glcur + hs_deg10 R_GLCAASE9ly subsystem: Hyaluronan Metabolism R_GLCAASE9ly equation: [l] : (2) h2o + ha_pre1 --> acgam + glcur R_GLCAASE5ly subsystem: Chondroitin sulfate degradation R_GLCAASE5ly equation: [l] : cs_c_deg2 + h2o --> cs_c_deg3 + glcur R_GLCAASE4ly subsystem: Chondroitin sulfate degradation R_GLCAASE4ly equation: [l] : cs_a_deg2 + h2o --> cs_a_deg3 + glcur R_GLCAASE6ly subsystem: Chondroitin sulfate degradation R_GLCAASE6ly equation: [l] : cs_d_deg3 + h2o --> cs_d_deg4 + glcur R_GLCAASE8ly subsystem: Hyaluronan Metabolism R_GLCAASE8ly equation: [l] : h2o + ha --> glcur + ha_deg1 R_GLCAASE7ly subsystem: Chondroitin sulfate degradation R_GLCAASE7ly equation: [l] : cs_e_deg3 + h2o --> cs_e_deg4 + glcur
product: 634572
reactant: 634476
product: 634548
product: 634524
is: http://identifiers.org/ec-code/3.2.1.31
fast: false
reactant: 634404
product: 634584

634416
type: SpeciesReference
stoichiometry: 1.0
species: 599677

599677
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: hyaluronan biosynthesis, precursor 1_C14H20NO11

634428
type: SpeciesReference
stoichiometry: 1.0
species: 593076

593076
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
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634524
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634404
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592812
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634584
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599629
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013840
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reactant: 661377
product: 661425
product: 661437
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661377
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584653
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661425
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589896
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name: Aldosterone_C21H28O5

661437
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661389
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661401
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661413
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661449
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597566
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609678
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596187
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008873
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product: 615762
reactant: 615387
reactant: 615424
product: 615592
product: 615689
reactant: 615496
reactant: 615400
reactant: 615568
product: 615677
reactant: 615375
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reactant: 615412
product: 615653
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product: 615580
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product: 615798
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reactant: 615508
reactant: 615520
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reactant: 615339
reactant: 615484
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product: 615750
product: 615665
reactant: 615532
reactant: 615460
notes: R_FAOXC2251836x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2251836x equation: [x] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_FAOXC180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC180x equation: [x] : coa + h2o + nad + o2 + stcoa --> accoa + h + h2o2 + nadh + pmtcoa R_FAOXC241181x subsystem: Fatty acid oxidation, peroxisome R_FAOXC241181x equation: [x] : (3) coa + (3) h2o + (3) nad + nrvnccoa + (3) o2 --> (3) accoa + (3) h + (3) h2o2 + (3) nadh + odecoa R_FAOXC2051843x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2051843x equation: [x] : coa + h2o + nad + tmndnccoa --> accoa + h + nadh + strdnccoa R_FAOXC2452253x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2452253x equation: [x] : coa + h2o + nad + o2 + tetpent3coa --> accoa + clpndcoa + h + h2o2 + nadh R_FAOXC2252053x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2252053x equation: [x] : coa + dcsptn1coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + tmndnccoa R_FAOXC183806x subsystem: Fatty acid oxidation, peroxisome R_FAOXC183806x equation: [x] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC200180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC200180x equation: [x] : arachcoa + coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + stcoa R_FAOXC16080x subsystem: Fatty acid oxidation, peroxisome R_FAOXC16080x equation: [x] : (4) coa + (4) h2o + (4) nad + (4) o2 + pmtcoa --> (4) accoa + (4) h + (4) h2o2 + (4) nadh + occoa R_FAOXC2242046x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2242046x equation: [x] : adrncoa + coa + h2o + nad + o2 --> accoa + arachdcoa + h + h2o2 + nadh R_FAOXC246226x subsystem: Fatty acid oxidation, peroxisome R_FAOXC246226x equation: [x] : coa + h2o + nad + o2 + tethex3coa --> accoa + c226coa + h + h2o2 + nadh R_ACOAO7p subsystem: Fatty Acid Metabolism R_ACOAO7p equation: [x] : o2 + pmtcoa --> h2o2 + hdd2coa R_FAOXC18480x subsystem: Fatty acid …
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product: 615641
reactant: 615351
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product: 615713
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reactant: 615448
reactant: 615363
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615762
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species: 588470

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610307
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name: tetracosapentaenoyl coenzyme A, n-3_C45H68N7O17P3S

615424
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species: 606021

615592
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species: 607583

607583
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name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S

615689
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species: 610933

610933
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name: timnodonyl coenzyme A_C41H60N7O17P3S

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species: 609764

609764
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name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S

615400
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species: 605309

605309
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boundary condition: false
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615568
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610379
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name: arachidyl coenzyme A_C41H70N7O17P3S

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species: 599506

599506
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name: H2O_H2O

615617
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species: 609860

609860
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initial concentration: NaN
initial amount: NaN
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name: stearidonyl coenzyme A_C39H58N7O17P3S

615412
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species: 609860

615653
type: SpeciesReference
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species: 605358

615580
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species: 592099

615725
type: SpeciesReference
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species: 603554

603554
type: Species
constant: false
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has only substance units: false
initial concentration: NaN
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name: gamma-linolenoyl-CoA_C39H60N7O17P3S

615798
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species: 590499

590499
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boundary condition: false
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name: C20:4-CoA_C41H62N7O17P3S

615738
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species: 591222

591222
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boundary condition: false
has only substance units: false
initial concentration: NaN
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name: cervonyl coenzyme A_C43H62N7O17P3S

615556
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species: 599977

599977
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name: Hexacosanoyl-CoA (n-C26:0CoA)_C47H82N7O17P3S

615508
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species: 610451

610451
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boundary condition: false
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name: tetracosatetraenoyl coenzyme A_C45H70N7O17P3S

615520
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species: 591222

615701
type: SpeciesReference
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species: 599617

615774
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species: 589410

589410
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name: adrenyl coenzyme A_C43H66N7O17P3S

615472
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species: 610933

615339
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species: 607583

615484
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species: 592414

615629
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species: 593960

593960
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initial concentration: NaN
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name: docosa-4,7,10,13,16-pentaenoyl coenzyme A_C43H64N7O17P3S

615750
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species: 599881

599881
type: Species
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615665
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species: 606371

606371
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name: Octadecenoyl-CoA (n-C18:1CoA)_C39H64N7O17P3S

615532
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species: 603554

615460
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species: 590403

615436
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species: 593960

615604
type: SpeciesReference
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species: 603240

603240
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initial concentration: NaN
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615641
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species: 606203

606203
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615351
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species: 605900

605900
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name: nervonyl coenzyme A_C45H76N7O17P3S

615544
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615713
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615786
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species: 599409

599409
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615448
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species: 610259

610259
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name: tetracosahexaenoyl coenzyme A_C45H66N7O17P3S

615363
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species: 603240

595510
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586712
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013298
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product: 655292
reactant: 655255
is: ENSECAG00000017998.1
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notes: R_DHCR243r subsystem: Cholesterol Metabolism R_DHCR243r equation: [r] : dsmsterol + fadh2 --> chsterol + fad R_DHCR242r subsystem: Cholesterol Metabolism R_DHCR242r equation: [r] : chlstol + fadh2 --> fad + lthstrl R_DHCR241r subsystem: Cholesterol Metabolism R_DHCR241r equation: [r] : fadh2 + zymst --> fad + zymstnl
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612620
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name: Zymostenol_C27H46O

655243
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species: 612608

612608
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name: zymosterol_C27H44O

655292
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species: 596336

596336
type: Species
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name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

655255
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species: 596384

596384
type: Species
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name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

655304
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591905
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name: Cholesterol_C27H46O

655231
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species: 595364

655280
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species: 603638

603638
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name: _5alpha-Cholest-7-en-3beta-ol_C27H46O

655268
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591616
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593245
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initial concentration: NaN
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in compartment: 584389
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 6_C31H48NO32S2

010484
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product: 630510
is: ENSECAG00000007738.1
is: http://identifiers.org/ec-code/2.4.1.149
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reactant: 630317
reactant: 630366
notes: R_AG13T6g subsystem: Keratan sulfate biosynthesis R_AG13T6g equation: [g] : ksi_pre6 + uacgam --> h + ksi_pre7 + udp R_AG13T17g subsystem: Keratan sulfate biosynthesis R_AG13T17g equation: [g] : ksii_core4_pre4 + uacgam --> h + ksii_core4_pre5 + udp R_AG13T2g subsystem: Keratan sulfate biosynthesis R_AG13T2g equation: [g] : ksii_core2_pre4 + uacgam --> h + ksii_core2_pre5 + udp R_AG13T5g subsystem: Keratan sulfate biosynthesis R_AG13T5g equation: [g] : ksi_pre3 + uacgam --> h + ksi_pre4 + udp R_AG13T8g subsystem: Keratan sulfate biosynthesis R_AG13T8g equation: [g] : ksi_pre12 + uacgam --> h + ksi_pre13 + udp R_AG13T12g subsystem: Keratan sulfate biosynthesis R_AG13T12g equation: [g] : ksi_pre24 + uacgam --> h + ksi_pre25 + udp R_AG13T1g subsystem: Keratan sulfate biosynthesis R_AG13T1g equation: [g] : ksii_core2_pre2 + uacgam --> h + ksii_core2_pre3 + udp R_AG13T10g subsystem: Keratan sulfate biosynthesis R_AG13T10g equation: [g] : ksi_pre18 + uacgam --> h + ksi_pre19 + udp R_AG13T14g subsystem: Keratan sulfate biosynthesis R_AG13T14g equation: [g] : ksi_pre30 + uacgam --> h + ksi_pre31 + udp R_AG13T13g subsystem: Keratan sulfate biosynthesis R_AG13T13g equation: [g] : ksi_pre27 + uacgam --> h + ksi_pre28 + udp R_AG13T9g subsystem: Keratan sulfate biosynthesis R_AG13T9g equation: [g] : ksi_pre15 + uacgam --> h + ksi_pre16 + udp R_AG13T15g subsystem: Keratan sulfate biosynthesis R_AG13T15g equation: [g] : ksi_pre33 + uacgam --> h + ksi_pre34 + udp R_AG13T4g subsystem: Keratan sulfate biosynthesis R_AG13T4g equation: [g] : ksi_pre1 + uacgam --> h + ksi_pre2 + udp R_AG13T11g subsystem: Keratan sulfate biosynthesis R_AG13T11g equation: [g] : ksi_pre21 + uacgam --> h + ksi_pre22 + udp R_AG13T16g subsystem: Keratan sulfate biosynthesis R_AG13T16g equation: [g] : ksii_core4_pre2 + uacgam --> h + ksii_core4_pre3 + udp R_AG13T18g subsystem: Keratan sulfate biosynthesis R_AG13T18g equation: [g] : ksii_core4_pre7 + uacgam --> h + ksii_core4_pre8 + udp R_AG13T7g subsystem: Ker…
reactant: 630221
product: 630474
reactant: 630305
product: 630522
reactant: 630354
reactant: 630390
product: 630679
is: ENSECAG00000011001.1
product: 630450
product: 630594
is: ENSECAG00000006840.1
reactant: 630269
reactant: 630438
product: 630570
reactant: 630257
product: 630642
product: 630558
product: 630486
is: ENSECAG00000006409.1
fast: false
is: ENSECAG00000001418.1
product: 630534
is: ENSECAG00000024670.1
product: 630606
reactant: 630342
reactant: 630293
reactant: 630426
product: 630654
reactant: 630245
reactant: 630281
reactant: 630414
reactant: 630329
reactant: 630233
reversible: false
reactant: 630402
product: 630582
product: 630462
product: 630618
product: 630498

630510
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species: 611417

630666
type: SpeciesReference
stoichiometry: 1.0
species: 602010

602010
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 16_C157H253N11O124S4X

630630
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stoichiometry: 1.0
species: 602299

602299
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 4_C101H165N7O72X

630546
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stoichiometry: 1.0
species: 601938

601938
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 10_C129H209N9O98S2X

630378
type: SpeciesReference
stoichiometry: 1.0
species: 602530

630317
type: SpeciesReference
stoichiometry: 1.0
species: 602238

630366
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species: 601998

630221
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species: 602202

630474
type: SpeciesReference
stoichiometry: 1.0
species: 602796

602796
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate II biosynthesis, precursor 8_C83H134N7O61SX

630305
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stoichiometry: 18.0
species: 611381

630522
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species: 602336

602336
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 7_C115H187N8O85SX

630354
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stoichiometry: 1.0
species: 602591

630390
type: SpeciesReference
stoichiometry: 1.0
species: 602724

602724
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate II boisynthesis, precursor 2_C47H76N4O33X

630679
type: SpeciesReference
stoichiometry: 1.0
species: 602046

602046
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 19_C171H275N12O137S5X

630450
type: SpeciesReference
stoichiometry: 1.0
species: 602736

630594
type: SpeciesReference
stoichiometry: 1.0
species: 602190

630269
type: SpeciesReference
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species: 602118

630438
type: SpeciesReference
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species: 602082

630570
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stoichiometry: 1.0
species: 602604

602604
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate II biosynthesis, precursor 8_C75H121N6O56SX

630257
type: SpeciesReference
stoichiometry: 1.0
species: 602784

630642
type: SpeciesReference
stoichiometry: 1.0
species: 602760

602760
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate II biosynthesis, precursor 5_C69H112N6O48X

630558
type: SpeciesReference
stoichiometry: 1.0
species: 602567

602567
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate II biosynthesis, precursor 5_C61H99N5O43X

630486
type: SpeciesReference
stoichiometry: 1.0
species: 602214

602214
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 31_C227H363N16O189S9X

630534
type: SpeciesReference
stoichiometry: 18.0
species: 599556

630606
type: SpeciesReference
stoichiometry: 1.0
species: 602543

630342
type: SpeciesReference
stoichiometry: 1.0
species: 602034

630293
type: SpeciesReference
stoichiometry: 1.0
species: 602058

602058
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 1_C79H129N5O57X

630426
type: SpeciesReference
stoichiometry: 1.0
species: 602323

630654
type: SpeciesReference
stoichiometry: 1.0
species: 602250

602250
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 34_C241H385N17O202S10X

630245
type: SpeciesReference
stoichiometry: 1.0
species: 602287

630281
type: SpeciesReference
stoichiometry: 1.0
species: 601961

630414
type: SpeciesReference
stoichiometry: 1.0
species: 602555

630329
type: SpeciesReference
stoichiometry: 1.0
species: 602361

630233
type: SpeciesReference
stoichiometry: 1.0
species: 602154

630402
type: SpeciesReference
stoichiometry: 1.0
species: 602748

630582
type: SpeciesReference
stoichiometry: 1.0
species: 602094

602094
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 22_C185H297N13O150S6X

630462
type: SpeciesReference
stoichiometry: 1.0
species: 602130

602130
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 25_C199H319N14O163S7X

630618
type: SpeciesReference
stoichiometry: 1.0
species: 601974

601974
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 13_C143H231N10O111S3X

630498
type: SpeciesReference
stoichiometry: 1.0
species: 602166

602166
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: keratan sulfate I biosynthesis, precursor 28_C213H341N15O176S8X

605031
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Myristoyl-ACP (n-C14:0ACP)_C25H47N2O8PRS

018515
type: Reaction
product: 706042
is: ENSECAG00000015865.1
name: glutamine synthetase
product: 706054
product: 706066
reactant: 706006
reversible: false
reactant: 705994
notes: R_GLNS subsystem: Glutamate metabolism R_GLNS equation: [c] : atp + glu-L + nh4 --> adp + gln-L + h + pi
is: http://identifiers.org/ec-code/6.3.1.2
fast: false
reactant: 706018
product: 706030
is: ENSECAG00000021630.1

706042
type: SpeciesReference
stoichiometry: 1.0
species: 598205

706054
type: SpeciesReference
stoichiometry: 1.0
species: 589206

706066
type: SpeciesReference
stoichiometry: 1.0
species: 599531

706006
type: SpeciesReference
stoichiometry: 1.0
species: 605563

705994
type: SpeciesReference
stoichiometry: 1.0
species: 590727

706018
type: SpeciesReference
stoichiometry: 1.0
species: 598265

706030
type: SpeciesReference
stoichiometry: 1.0
species: 607462

609581
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Sphingosine_C18H38NO2

601853
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 6_C210H336N15O184S11

595835
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Eicosatetranoyl carnitine_C27H45NO4

610151
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Thiocyanate_CNS

587056
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5-Hydroxykynurenamine_C9H13N2O2

019332
type: Reaction
fast: false
is: http://identifiers.org/ec-code/3.5.2.2
is: ENSECAG00000020200.1
product: 715153
reactant: 715117
is: ENSECAG00000008662.1
product: 715141
reversible: false
notes: R_DHPM1 subsystem: Pyrimidine Catabolism R_DHPM1 equation: [c] : 56dura + h2o --> cala + h
reactant: 715129
name: dihydropyrimidinase (5,6-dihydrouracil)
is: ENSECAG00000020271.1

715153
type: SpeciesReference
stoichiometry: 1.0
species: 599531

715117
type: SpeciesReference
stoichiometry: 1.0
species: 586688

586688
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5,6-dihydrouracil_C4H6N2O2

715141
type: SpeciesReference
stoichiometry: 1.0
species: 591307

591307
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-Carbamoyl-beta-alanine_C4H7N2O3

715129
type: SpeciesReference
stoichiometry: 1.0
species: 599421

014923
type: Reaction
reactant: 670734
reactant: 670710
product: 670914
reactant: 670746
reactant: 670806
reactant: 670722
notes: R_ALAASNNaEx subsystem: Transport, Extracellular R_ALAASNNaEx equation: ala-L[e] + asn-L[c] + na1[e] --> ala-L[c] + asn-L[e] + na1[c] R_SERASNNaEx subsystem: Transport, Extracellular R_SERASNNaEx equation: asn-L[c] + na1[e] + ser-L[e] --> asn-L[e] + na1[c] + ser-L[c] R_GLNSERNaEx subsystem: Transport, Extracellular R_GLNSERNaEx equation: gln-L[e] + na1[e] + ser-L[c] --> gln-L[c] + na1[c] + ser-L[e] R_SERGLNNaEx subsystem: Transport, Extracellular R_SERGLNNaEx equation: gln-L[c] + na1[e] + ser-L[e] --> gln-L[e] + na1[c] + ser-L[c] R_CYSTHRNaEx subsystem: Transport, Extracellular R_CYSTHRNaEx equation: cys-L[e] + na1[e] + thr-L[c] --> cys-L[c] + na1[c] + thr-L[e] R_ASNGLNNaEx subsystem: Transport, Extracellular R_ASNGLNNaEx equation: asn-L[e] + gln-L[c] + na1[e] --> asn-L[c] + gln-L[e] + na1[c] R_GLNTHRNaEx subsystem: Transport, Extracellular R_GLNTHRNaEx equation: gln-L[e] + na1[e] + thr-L[c] --> gln-L[c] + na1[c] + thr-L[e] R_ASNTHRNaEx subsystem: Transport, Extracellular R_ASNTHRNaEx equation: asn-L[e] + na1[e] + thr-L[c] --> asn-L[c] + na1[c] + thr-L[e] R_THRSERNaEx subsystem: Transport, Extracellular R_THRSERNaEx equation: na1[e] + ser-L[c] + thr-L[e] --> na1[c] + ser-L[e] + thr-L[c] R_ALACYSNaEx subsystem: Transport, Extracellular R_ALACYSNaEx equation: ala-L[e] + cys-L[c] + na1[e] --> ala-L[c] + cys-L[e] + na1[c] R_GLNCYSNaEx subsystem: Transport, Extracellular R_GLNCYSNaEx equation: cys-L[c] + gln-L[e] + na1[e] --> cys-L[e] + gln-L[c] + na1[c] R_THRALANaEx subsystem: Transport, Extracellular R_THRALANaEx equation: ala-L[c] + na1[e] + thr-L[e] --> ala-L[e] + na1[c] + thr-L[c] R_GLNASNNaEx subsystem: Transport, Extracellular R_GLNASNNaEx equation: asn-L[c] + gln-L[e] + na1[e] --> asn-L[e] + gln-L[c] + na1[c] R_CYSALANaEx subsystem: Transport, Extracellular R_CYSALANaEx equation: ala-L[c] + cys-L[e] + na1[e] --> ala-L[e] + cys-L[c] + na1[c] R_CYSGLNNaEx subsystem: Transport, Extracellular R_CYSGLNNaEx equation: cys-L[e] + gln-L[c] + na1[e] --> cys-L[c] + gln-L[e]…
reactant: 670830
product: 670854
product: 670938
reactant: 670818
product: 670950
product: 670866
reactant: 670770
product: 670974
product: 670926
product: 670902
reactant: 670794
reversible: false
fast: false
reactant: 670698
reactant: 670782
reactant: 670686
product: 670962
product: 670842
reactant: 670758
product: 670878
product: 670986
product: 670890
is: ENSECAG00000011637.1

670734
type: SpeciesReference
stoichiometry: 5.0
species: 598205

670710
type: SpeciesReference
stoichiometry: 5.0
species: 589847

670914
type: SpeciesReference
stoichiometry: 30.0
species: 605187

670746
type: SpeciesReference
stoichiometry: 5.0
species: 590631

670806
type: SpeciesReference
stoichiometry: 5.0
species: 598217

670722
type: SpeciesReference
stoichiometry: 5.0
species: 593512

593512
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Cysteine_C3H7NO2S

670830
type: SpeciesReference
stoichiometry: 5.0
species: 609364

670854
type: SpeciesReference
stoichiometry: 5.0
species: 609352

670938
type: SpeciesReference
stoichiometry: 5.0
species: 610764

670818
type: SpeciesReference
stoichiometry: 5.0
species: 589834

670950
type: SpeciesReference
stoichiometry: 5.0
species: 610752

670866
type: SpeciesReference
stoichiometry: 5.0
species: 589847

670770
type: SpeciesReference
stoichiometry: 5.0
species: 590619

670974
type: SpeciesReference
stoichiometry: 5.0
species: 609364

670926
type: SpeciesReference
stoichiometry: 5.0
species: 590619

670902
type: SpeciesReference
stoichiometry: 5.0
species: 590631

670794
type: SpeciesReference
stoichiometry: 5.0
species: 610752

670698
type: SpeciesReference
stoichiometry: 5.0
species: 609352

670782
type: SpeciesReference
stoichiometry: 5.0
species: 610764

670686
type: SpeciesReference
stoichiometry: 5.0
species: 593500

670962
type: SpeciesReference
stoichiometry: 5.0
species: 598217

670842
type: SpeciesReference
stoichiometry: 5.0
species: 593500

670758
type: SpeciesReference
stoichiometry: 30.0
species: 605200

670878
type: SpeciesReference
stoichiometry: 5.0
species: 593512

670986
type: SpeciesReference
stoichiometry: 5.0
species: 589834

670890
type: SpeciesReference
stoichiometry: 5.0
species: 598205

608507
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: pendtadenoyl carnitine_C22H43NO4

014334
type: Reaction
is: ENSECAG00000004260.1
product: 666313
notes: R_NAt3_1g subsystem: Transport, Golgi Apparatus R_NAt3_1g equation: h[g] + na1[c] <==> h[c] + na1[g] R_Kt3g subsystem: Transport, Golgi Apparatus R_Kt3g equation: h[g] + k[c] <==> h[c] + k[g]
product: 666325
fast: false
reactant: 666301
product: 666337
reactant: 666277
reversible: true
is: ENSECAG00000019227.1
reactant: 666289

666313
type: SpeciesReference
stoichiometry: 1.0
species: 601371

601371
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: potassium_K

666325
type: SpeciesReference
stoichiometry: 1.0
species: 605212

605212
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Sodium_Na

666301
type: SpeciesReference
stoichiometry: 1.0
species: 605187

666337
type: SpeciesReference
stoichiometry: 2.0
species: 599531

666277
type: SpeciesReference
stoichiometry: 1.0
species: 601347

601347
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: potassium_K

666289
type: SpeciesReference
stoichiometry: 2.0
species: 599556

018875
type: Reaction
notes: R_ARABR subsystem: Pentose and Glucuronate Interconversions R_ARABR equation: [c] : arab-L + h + nadph --> abt + nadp R_LALDO2 subsystem: Pyruvate Metabolism R_LALDO2 equation: [c] : h + mthgxl + nadph --> lald-D + nadp R_LALDO2x subsystem: Pyruvate Metabolism R_LALDO2x equation: [c] : h + mthgxl + nadh --> lald-D + nad R_ALR3 subsystem: Pyruvate Metabolism R_ALR3 equation: [c] : acetol + h + nadph --> 12ppd-S + nadp R_PPDOx subsystem: Pyruvate Metabolism R_PPDOx equation: [c] : h + lald-D + nadh --> 12ppd-R + nad R_SBTR subsystem: Fructose and Mannose Metabolism R_SBTR equation: [c] : glc-D + h + nadph --> nadp + sbt-D R_ALR2 subsystem: Pyruvate Metabolism R_ALR2 equation: [c] : h + mthgxl + nadph --> acetol + nadp R_PPDOy subsystem: Pyruvate Metabolism R_PPDOy equation: [c] : h + lald-D + nadph --> 12ppd-R + nadp
reversible: false
reactant: 711200
product: 711284
product: 711296
product: 711332
is: ENSECAG00000000594.1
reactant: 711152
product: 711320
is: ENSECAG00000006082.1
product: 711248
reactant: 711212
product: 711308
reactant: 711224
reactant: 711164
is: http://identifiers.org/ec-code/1.1.1.21
reactant: 711236
fast: false
product: 711272
reactant: 711176
product: 711260
reactant: 711188

711200
type: SpeciesReference
stoichiometry: 1.0
species: 588482

588482
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Acetol_C3H6O2

711284
type: SpeciesReference
stoichiometry: 2.0
species: 605248

711296
type: SpeciesReference
stoichiometry: 6.0
species: 605370

711332
type: SpeciesReference
stoichiometry: 1.0
species: 588482

711152
type: SpeciesReference
stoichiometry: 3.0
species: 605019

605019
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Methylglyoxal_C3H4O2

711320
type: SpeciesReference
stoichiometry: 1.0
species: 609172

609172
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Sorbitol_C6H14O6

711248
type: SpeciesReference
stoichiometry: 1.0
species: 584725

584725
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: (S)-Propane-1,2-diol_C3H8O2

711212
type: SpeciesReference
stoichiometry: 8.0
species: 599531

711308
type: SpeciesReference
stoichiometry: 2.0
species: 602940

602940
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Lactaldehyde_C3H6O2

711224
type: SpeciesReference
stoichiometry: 2.0
species: 605322

711164
type: SpeciesReference
stoichiometry: 1.0
species: 590343

590343
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Arabinose_C5H10O5

711236
type: SpeciesReference
stoichiometry: 6.0
species: 605442

711272
type: SpeciesReference
stoichiometry: 2.0
species: 584713

584713
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: (R)-Propane-1,2-diol_C3H8O2

711176
type: SpeciesReference
stoichiometry: 1.0
species: 598097

711260
type: SpeciesReference
stoichiometry: 1.0
species: 588240

588240
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Arabinitol_C5H12O5

711188
type: SpeciesReference
stoichiometry: 2.0
species: 602940

010773
type: Reaction
product: 632933
product: 632957
is: http://identifiers.org/ec-code/2.4.1.80
notes: R_UGCG subsystem: Sphingolipid Metabolism R_UGCG equation: [r] : crm_hs + udpg --> gluside_hs + h + udp
reactant: 632909
reversible: false
name: Ceramide glucosyltransferase
reactant: 632921
fast: false
product: 632945
is: ENSECAG00000002866.1

632933
type: SpeciesReference
stoichiometry: 1.0
species: 611465

611465
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: UDP_C9H11N2O12P2

632957
type: SpeciesReference
stoichiometry: 1.0
species: 598386

598386
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO

632909
type: SpeciesReference
stoichiometry: 1.0
species: 611549

611549
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: UDPglucose_C15H22N2O17P2

632921
type: SpeciesReference
stoichiometry: 1.0
species: 592607

592607
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

632945
type: SpeciesReference
stoichiometry: 1.0
species: 599605

584858
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _18 hydroxy arachidonic acid_C20H31O3

012839
type: Reaction
reactant: 651060
reversible: true
reactant: 651048
is: http://identifiers.org/ec-code/1.6.1.1
product: 651084
reactant: 651035
product: 651072
name: NAD(P) transhydrogenase
product: 651096
is: ENSECAG00000016077.1
notes: R_THD1m subsystem: NAD Metabolism R_THD1m equation: h[c] + nadh[m] + nadp[m] <==> h[m] + nad[m] + nadph[m]
fast: false

651060
type: SpeciesReference
stoichiometry: 1.0
species: 605334

651048
type: SpeciesReference
stoichiometry: 1.0
species: 599531

651084
type: SpeciesReference
stoichiometry: 1.0
species: 605454

651035
type: SpeciesReference
stoichiometry: 1.0
species: 605394

651072
type: SpeciesReference
stoichiometry: 1.0
species: 605272

651096
type: SpeciesReference
stoichiometry: 1.0
species: 599581

596999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Leb glycolipid_C56H99N2O30FULLRCO

595920
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: phosphoethanolaminyl-trimannosyl-glucosaminyl-acylphosphatidylinositol (H6')_C51H94N2O32P2FULLRCO2FULLR2CO2

018683
type: Reaction
product: 707730
reactant: 707634
product: 707937
product: 707779
reactant: 707646
is: ENSECAG00000023318.1
product: 707840
notes: R_S6TASE23ly subsystem: Keratan sulfate degradation R_S6TASE23ly equation: [l] : h2o + ksii_core2_deg3 <==> h + ksii_core2_deg4 + so4 R_S6TASE15ly subsystem: Keratan sulfate degradation R_S6TASE15ly equation: [l] : h2o + ksi_deg18 <==> h + ksi_deg19 + so4 R_S6TASE13ly subsystem: Keratan sulfate degradation R_S6TASE13ly equation: [l] : h2o + ksi_deg12 <==> h + ksi_deg13 + so4 R_S6TASE26ly subsystem: Keratan sulfate degradation R_S6TASE26ly equation: [l] : h2o + ksii_core4_deg3 <==> h + ksii_core4_deg4 + so4 R_S6TASE12ly subsystem: Keratan sulfate degradation R_S6TASE12ly equation: [l] : h2o + ksi_deg9 <==> h + ksi_deg10 + so4 R_S6TASE20ly subsystem: Keratan sulfate degradation R_S6TASE20ly equation: [l] : h2o + ksi_deg33 <==> h + ksi_deg34 + so4 R_S6TASE17ly subsystem: Keratan sulfate degradation R_S6TASE17ly equation: [l] : h2o + ksi_deg24 <==> h + ksi_deg25 + so4 R_S6TASE21ly subsystem: Keratan sulfate degradation R_S6TASE21ly equation: [l] : h2o + ksi_deg36 <==> h + ksi_deg37 + so4 R_S6TASE11ly subsystem: Keratan sulfate degradation R_S6TASE11ly equation: [l] : h2o + ksi_deg6 <==> h + ksi_deg7 + so4 R_S6TASE3ly subsystem: Heparan sulfate degradation R_S6TASE3ly equation: [l] : h2o + hs_deg11 <==> h + hs_deg12 + so4 R_S6TASE1ly subsystem: Heparan sulfate degradation R_S6TASE1ly equation: [l] : h2o + hs <==> h + hs_deg1 + so4 R_S6TASE24ly subsystem: Keratan sulfate degradation R_S6TASE24ly equation: [l] : h2o + ksii_core2_deg6 <==> h + ksii_core2_deg7 + so4 R_S6TASE2ly subsystem: Heparan sulfate degradation R_S6TASE2ly equation: [l] : h2o + hs_deg5 <==> h + hs_deg6 + so4 R_S6TASE16ly subsystem: Keratan sulfate degradation R_S6TASE16ly equation: [l] : h2o + ksi_deg21 <==> h + ksi_deg22 + so4 R_S6TASE14ly subsystem: Keratan sulfate degradation R_S6TASE14ly equation: [l] : h2o + ksi_deg15 <==> h + ksi_deg16 + so4 R_S6TASE19ly subsystem: Keratan sulfate degradation R_S6TASE19ly equation: [l] : h2o + ksi_deg30 <==> h + ksi_deg31 + so4 R_S6TASE18ly subsystem: Keratan sulf…
reactant: 707694
product: 707718
reactant: 707574
reactant: 707526
reversible: true
fast: false
reactant: 707622
product: 707803
product: 707900
product: 707925
is: http://identifiers.org/ec-code/3.1.6.14
product: 707791
product: 707827
product: 707913
product: 707743
reactant: 707682
reactant: 707502
reactant: 707514
reactant: 707706
product: 707864
reactant: 707562
product: 707767
product: 707852
product: 707755
reactant: 707658
reactant: 707538
product: 707815
reactant: 707610
product: 707888
reactant: 707586
reactant: 707598
product: 707876
reactant: 707670
reactant: 707550

707730
type: SpeciesReference
stoichiometry: 17.0
species: 609497

609497
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Sulfate_O4S

707634
type: SpeciesReference
stoichiometry: 1.0
species: 602397

602397
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate II (core 2-linked), degradation product 3_C58H94N5O46S2X

707937
type: SpeciesReference
stoichiometry: 1.0
species: 601503

601503
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 19_C146H236N10O124S6

707779
type: SpeciesReference
stoichiometry: 1.0
species: 601719

601719
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 34_C76H126N5O59S1

707646
type: SpeciesReference
stoichiometry: 1.0
species: 601623

707840
type: SpeciesReference
stoichiometry: 1.0
species: 601467

707694
type: SpeciesReference
stoichiometry: 1.0
species: 601707

601707
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 33_C76H125N5O62S2

707718
type: SpeciesReference
stoichiometry: 1.0
species: 601431

601431
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 13_C174H280N12O150S8

707574
type: SpeciesReference
stoichiometry: 1.0
species: 601419

601419
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 12_C174H279N12O153S9

707526
type: SpeciesReference
stoichiometry: 1.0
species: 602652

602652
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate II (core 4-linked), degradation product 3_C66H107N6O51S2X

707622
type: SpeciesReference
stoichiometry: 1.0
species: 601455

601455
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 15_C160H257N11O140S8

707803
type: SpeciesReference
stoichiometry: 17.0
species: 599568

707900
type: SpeciesReference
stoichiometry: 1.0
species: 601755

601755
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 37_C62H104N4O46

707925
type: SpeciesReference
stoichiometry: 1.0
species: 601599

601599
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 25_C118H192N8O98S4

707791
type: SpeciesReference
stoichiometry: 1.0
species: 601395

601395
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 10_C188H302N13O163S9

707827
type: SpeciesReference
stoichiometry: 1.0
species: 601683

601683
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 31_C90H148N6O72S2

707913
type: SpeciesReference
stoichiometry: 1.0
species: 602446

602446
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate II (core 2-linked), degradation product 7_C44H73N4O30X

707743
type: SpeciesReference
stoichiometry: 1.0
species: 601635

601635
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 28_C104H170N7O85S3

707682
type: SpeciesReference
stoichiometry: 1.0
species: 601551

601551
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 21_C132H213N9O114S6

707502
type: SpeciesReference
stoichiometry: 1.0
species: 600514

600514
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: heparan sulfate, degradation product 5_C67H97N4O86S10

707514
type: SpeciesReference
stoichiometry: 1.0
species: 600285

600285
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: heparan sulfate, degradation product 11_C55H81N3O67S7

707706
type: SpeciesReference
stoichiometry: 1.0
species: 601853

707864
type: SpeciesReference
stoichiometry: 1.0
species: 602664

602664
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate II (core 4-linked), degradation product 4_C66H108N6O48SX

707562
type: SpeciesReference
stoichiometry: 1.0
species: 601587

601587
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 24_C118H191N8O101S5

707767
type: SpeciesReference
stoichiometry: 1.0
species: 601865

601865
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 7_C210H337N15O181S10

707852
type: SpeciesReference
stoichiometry: 1.0
species: 602409

602409
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate II (core 2-linked), degradation product 4_C58H95N5O43SX

707755
type: SpeciesReference
stoichiometry: 1.0
species: 601563

601563
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 22_C132H214N9O111S5

707658
type: SpeciesReference
stoichiometry: 1.0
species: 600575

707538
type: SpeciesReference
stoichiometry: 1.0
species: 601491

601491
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 18_C146H235N10O127S7

707815
type: SpeciesReference
stoichiometry: 1.0
species: 600394

600394
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: heparan sulfate, degradation product 1_C79H115N5O99S11

707610
type: SpeciesReference
stoichiometry: 1.0
species: 601743

601743
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 36_C62H103N4O49S1

707888
type: SpeciesReference
stoichiometry: 1.0
species: 600526

600526
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: heparan sulfate, degradation product 6_C67H98N4O83S9

707586
type: SpeciesReference
stoichiometry: 17.0
species: 599457

707598
type: SpeciesReference
stoichiometry: 1.0
species: 601889

601889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 9_C188H301N13O166S10

707876
type: SpeciesReference
stoichiometry: 1.0
species: 600298

600298
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: heparan sulfate, degradation product 12_C55H82N3O64S6

707670
type: SpeciesReference
stoichiometry: 1.0
species: 601671

601671
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 30_C90H147N6O75S3

707550
type: SpeciesReference
stoichiometry: 1.0
species: 602433

602433
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate II (core 2-linked), degradation product 6_C44H72N4O33SX

609521
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Sulfate_O4S

587212
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: haxglutamyl folate (DHF)_C44H49N12O21

604343
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: D-Mannose_C6H12O6

603698
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: L-Lysine_C6H15N2O2

607280
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: phosphatidyl glycerol phosphate (homo sapiens)_C6H11O9P2FULLRCO2FULLR2CO2

599797
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Hexadecenoate (n-C16:1)_C16H29O2

584581
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _10-Formyltetrahydrofolate_C20H21N7O7

605382
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

009477
type: Reaction
reactant: 621037
reactant: 621025
reactant: 620964
reactant: 620951
reactant: 620989
is: ENSECAG00000021061.1
product: 621101
reactant: 621001
product: 621286
fast: false
reactant: 620914
product: 621114
product: 621273
reactant: 621049
product: 621176
product: 621237
reactant: 620890
product: 621188
notes: R_VALt4 subsystem: Transport, Extracellular R_VALt4 equation: na1[e] + val-L[e] --> na1[c] + val-L[c] R_THRt4 subsystem: Transport, Extracellular R_THRt4 equation: na1[e] + thr-L[e] --> na1[c] + thr-L[c] R_ILEt4 subsystem: Transport, Extracellular R_ILEt4 equation: ile-L[e] + na1[e] --> ile-L[c] + na1[c] R_METt4 subsystem: Transport, Extracellular R_METt4 equation: met-L[e] + na1[e] --> met-L[c] + na1[c] R_HISt4 subsystem: Transport, Extracellular R_HISt4 equation: his-L[e] + na1[e] --> his-L[c] + na1[c] R_LEUt4 subsystem: Transport, Extracellular R_LEUt4 equation: leu-L[e] + na1[e] --> leu-L[c] + na1[c] R_SERt4 subsystem: Transport, Extracellular R_SERt4 equation: na1[e] + ser-L[e] --> na1[c] + ser-L[c] R_ALAt4 subsystem: Transport, Extracellular R_ALAt4 equation: ala-L[e] + na1[e] --> ala-L[c] + na1[c] R_TYRt4 subsystem: Transport, Extracellular R_TYRt4 equation: na1[e] + tyr-L[e] --> na1[c] + tyr-L[c] R_CYSt4 subsystem: Transport, Extracellular R_CYSt4 equation: cys-L[e] + na1[e] --> cys-L[c] + na1[c] R_ARGt4 subsystem: Transport, Extracellular R_ARGt4 equation: arg-L[e] + na1[e] --> arg-L[c] + na1[c] R_ASNt4 subsystem: Transport, Extracellular R_ASNt4 equation: asn-L[e] + na1[e] --> asn-L[c] + na1[c] R_TRPt4 subsystem: Transport, Extracellular R_TRPt4 equation: na1[e] + trp-L[e] --> na1[c] + trp-L[c] R_GLYt4 subsystem: Transport, Extracellular R_GLYt4 equation: gly[e] + na1[e] --> gly[c] + na1[c] R_PHEt4 subsystem: Transport, Extracellular R_PHEt4 equation: na1[e] + phe-L[e] --> na1[c] + phe-L[c] R_GLNt4 subsystem: Transport, Extracellular R_GLNt4 equation: gln-L[e] + na1[e] --> gln-L[c] + na1[c] R_LYSt4 subsystem: Transport, Extracellular R_LYSt4 equation: lys-L[e] + na1[e] --> lys-L[c] + na1[c]
reactant: 621013
reactant: 621062
reactant: 620866
product: 621249
product: 621261
reactant: 620939
reactant: 620926
product: 621225
product: 621075
product: 621200
reactant: 620977
product: 621152
product: 621213
reversible: false
reactant: 620902
product: 621088
product: 621164
product: 621128
reactant: 620878
product: 621140
reactant: 620854

621037
type: SpeciesReference
stoichiometry: 1.0
species: 612022

612022
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Valine_C5H11NO2

621025
type: SpeciesReference
stoichiometry: 1.0
species: 607304

620964
type: SpeciesReference
stoichiometry: 1.0
species: 589847

620951
type: SpeciesReference
stoichiometry: 1.0
species: 611345

611345
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Tyrosine_C9H11NO3

620989
type: SpeciesReference
stoichiometry: 1.0
species: 609364

621101
type: SpeciesReference
stoichiometry: 1.0
species: 603662

603662
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Lysine_C6H15N2O2

621001
type: SpeciesReference
stoichiometry: 1.0
species: 590631

621286
type: SpeciesReference
stoichiometry: 17.0
species: 605187

620914
type: SpeciesReference
stoichiometry: 1.0
species: 610764

621114
type: SpeciesReference
stoichiometry: 1.0
species: 598446

621273
type: SpeciesReference
stoichiometry: 1.0
species: 600025

600025
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Histidine_C6H9N3O2

621049
type: SpeciesReference
stoichiometry: 17.0
species: 605200

621176
type: SpeciesReference
stoichiometry: 1.0
species: 603048

621237
type: SpeciesReference
stoichiometry: 1.0
species: 598205

620890
type: SpeciesReference
stoichiometry: 1.0
species: 611102

611102
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Tryptophan_C11H12N2O2

621188
type: SpeciesReference
stoichiometry: 1.0
species: 610752

621013
type: SpeciesReference
stoichiometry: 1.0
species: 604572

621062
type: SpeciesReference
stoichiometry: 1.0
species: 601044

601044
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Isoleucine_C6H13NO2

620866
type: SpeciesReference
stoichiometry: 1.0
species: 598458

621249
type: SpeciesReference
stoichiometry: 1.0
species: 607292

621261
type: SpeciesReference
stoichiometry: 1.0
species: 611090

611090
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Tryptophan_C11H12N2O2

620939
type: SpeciesReference
stoichiometry: 1.0
species: 603060

620926
type: SpeciesReference
stoichiometry: 1.0
species: 598217

621225
type: SpeciesReference
stoichiometry: 1.0
species: 601032

621075
type: SpeciesReference
stoichiometry: 1.0
species: 590619

621200
type: SpeciesReference
stoichiometry: 1.0
species: 612010

612010
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Valine_C5H11NO2

620977
type: SpeciesReference
stoichiometry: 1.0
species: 593512

621152
type: SpeciesReference
stoichiometry: 1.0
species: 611333

621213
type: SpeciesReference
stoichiometry: 1.0
species: 589834

620902
type: SpeciesReference
stoichiometry: 1.0
species: 600037

600037
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Histidine_C6H9N3O2

621088
type: SpeciesReference
stoichiometry: 1.0
species: 590547

590547
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Arginine_C6H15N4O2

621164
type: SpeciesReference
stoichiometry: 1.0
species: 604560

621128
type: SpeciesReference
stoichiometry: 1.0
species: 593500

620878
type: SpeciesReference
stoichiometry: 1.0
species: 603674

603674
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Lysine_C6H15N2O2

621140
type: SpeciesReference
stoichiometry: 1.0
species: 609352

620854
type: SpeciesReference
stoichiometry: 1.0
species: 590559

590559
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Arginine_C6H15N4O2

011920
type: Reaction
product: 642164
fast: false
reversible: false
name: g-glutamyltransferase (e)
is: ENSECAG00000000097.1
product: 642151
reactant: 642139
is: http://identifiers.org/ec-code/2.3.2.2
reactant: 642127
notes: R_GTMLTe subsystem: Glutathione Metabolism R_GTMLTe equation: ala-L[c] + gthrd[c] --> cgly[e] + gluala[e]

642164
type: SpeciesReference
stoichiometry: 1.0
species: 598326

642151
type: SpeciesReference
stoichiometry: 1.0
species: 591580

591580
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Cys-Gly_C5H10N2O3S

642139
type: SpeciesReference
stoichiometry: 1.0
species: 589834

642127
type: SpeciesReference
stoichiometry: 1.0
species: 599192

596264
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Fructose 1-phosphate_C6H11O9P

610824
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Thymidine_C10H14N2O5

589314
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: ADPribose_C15H21N5O14P2

611162
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: testosterone glucuronide_C25H36O8

591556
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: CDPethanolamine_C11H19N4O11P2

590283
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Apocarboxylase (Lys residue)_C6H13N2OX

611114
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Tryptamine_C10H13N2

018010
type: Reaction
fast: false
reversible: false
product: 701717
notes: R_ACCOAC subsystem: Fatty Acid Metabolism R_ACCOAC equation: [c] : accoa + atp + hco3 --> adp + h + malcoa + pi
reactant: 701681
reactant: 701693
product: 701741
reactant: 701669
is: http://identifiers.org/ec-code/6.4.1.2
is: ENSECAG00000010631.1
name: acetyl-CoA carboxylase
product: 701705
product: 701729

701717
type: SpeciesReference
stoichiometry: 1.0
species: 604197

604197
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Malonyl-CoA_C24H33N7O19P3S

701681
type: SpeciesReference
stoichiometry: 1.0
species: 590727

701693
type: SpeciesReference
stoichiometry: 1.0
species: 588408

701741
type: SpeciesReference
stoichiometry: 1.0
species: 599531

701669
type: SpeciesReference
stoichiometry: 1.0
species: 599689

701705
type: SpeciesReference
stoichiometry: 1.0
species: 607462

701729
type: SpeciesReference
stoichiometry: 1.0
species: 589206

593052
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 1_C45H66N2O49S4

604862
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: myo-Inositol hexakisphosphate_C6H6O24P6

605127
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: reducing GlcNAc removed form of n2m2nmasn (w/o peptide)_C50H84N4O36

603806
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: (alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C46H77N2O35X

610788
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Thymine_C5H6N2O2

013622
type: Reaction
product: 659852
reversible: true
reactant: 659828
name: inositol transport via sodium symport
is: ENSECAG00000015713.1
fast: false
notes: R_INSTt4_2 subsystem: Transport, Extracellular R_INSTt4_2 equation: inost[e] + (2) na1[e] <==> inost[c] + (2) na1[c]
product: 659840
is: ENSECAG00000000559.1
reactant: 659816
is: ENSECAG00000015213.1

659852
type: SpeciesReference
stoichiometry: 1.0
species: 601166

659828
type: SpeciesReference
stoichiometry: 1.0
species: 601178

601178
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: myo-Inositol_C6H12O6

659840
type: SpeciesReference
stoichiometry: 2.0
species: 605187

659816
type: SpeciesReference
stoichiometry: 2.0
species: 605200

013948
type: Reaction
reactant: 661991
reversible: true
is: ENSECAG00000009055.1
fast: false
product: 662075
product: 662051
reactant: 661979
reactant: 662003
product: 662087
product: 662039
is: ENSECAG00000013738.1
product: 662063
reactant: 662027
reactant: 662015
notes: R_3SALAASPm subsystem: Transport, Mitochondrial R_3SALAASPm equation: _3sala[m] + asp-L[c] <==> 3sala[c] + asp-L[m] R_ASPGLUm subsystem: Transport, Mitochondrial R_ASPGLUm equation: asp-L[m] + glu-L[c] + h[c] <==> asp-L[c] + glu-L[m] + h[m] R_GLUt2m subsystem: Transport, Mitochondrial R_GLUt2m equation: glu-L[c] + h[c] <==> glu-L[m] + h[m]

661991
type: SpeciesReference
stoichiometry: 2.0
species: 598265

662075
type: SpeciesReference
stoichiometry: 1.0
species: 590715

590715
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Aspartate_C4H6NO4

662051
type: SpeciesReference
stoichiometry: 2.0
species: 598301

661979
type: SpeciesReference
stoichiometry: 1.0
species: 586095

586095
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _3-Sulfino-L-alanine_C3H5NO4S

662003
type: SpeciesReference
stoichiometry: 1.0
species: 590691

662087
type: SpeciesReference
stoichiometry: 2.0
species: 599581

662039
type: SpeciesReference
stoichiometry: 1.0
species: 586082

662063
type: SpeciesReference
stoichiometry: 1.0
species: 590691

662027
type: SpeciesReference
stoichiometry: 2.0
species: 599531

662015
type: SpeciesReference
stoichiometry: 1.0
species: 590715

600430
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: heparan sulfate, degradation product 22_C37H56NO35S

608235
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Prostaglandin D2_C20H31O5

596444
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Formaldehyde_CH2O

596528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Ferricytochrome c_C42H54FeN8O6S2

600151
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Homoserine_C4H9NO3

586858
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: pentaglutamyl folate (DHF)_C39H43N11O18

590415
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: arachidyl carnitine_C27H53NO4

611986
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Vaccenyl carnitine_C25H47NO4

009586
type: Reaction
reversible: false
is: http://identifiers.org/ec-code/3.2.1.26
is: ENSECAG00000021256.1
product: 621951
product: 621963
reactant: 621903
reactant: 621890
reactant: 621915
product: 621939
fast: false
is: http://identifiers.org/ec-code/3.2.1.10
notes: R_O16G1e subsystem: Starch and Sucrose Metabolism R_O16G1e equation: [e] : glygn4 + h2o --> glc-D + glygn5 R_SUCRe subsystem: Galactose metabolism R_SUCRe equation: [e] : h2o + sucr --> fru + glc-D R_O16G2e subsystem: Starch and Sucrose Metabolism R_O16G2e equation: [e] : h2o + strch2 --> glc-D + malt
product: 621975
reactant: 621927

621951
type: SpeciesReference
stoichiometry: 1.0
species: 596768

596768
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: D-Fructose_C6H12O6

621963
type: SpeciesReference
stoichiometry: 1.0
species: 604246

604246
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Maltose_C12H22O11

621903
type: SpeciesReference
stoichiometry: 1.0
species: 609970

609970
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Sucrose_C12H22O11

621890
type: SpeciesReference
stoichiometry: 1.0
species: 609812

609812
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: starch, structure 2 (1,6-{2[1,4-Glc], [1,4-Glc]})_C18H32O16

621915
type: SpeciesReference
stoichiometry: 1.0
species: 598711

598711
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: glycogen, structure 4 (glycogenin-1,6-{2[1,4-Glc], [1,4-Glc]})_C18H31O16X

621939
type: SpeciesReference
stoichiometry: 1.0
species: 598724

598724
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: glycogen, structure 5 (glycogenin-2[1,4-Glc])_C12H21O11X

621975
type: SpeciesReference
stoichiometry: 3.0
species: 598109

621927
type: SpeciesReference
stoichiometry: 3.0
species: 599433

584798
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _15-Hydroperoxyeicosatetraenoic acid_C20H31O4

603036
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Lactose_C12H22O11

587611
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Cysteate_C3H6NO5S

611261
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: tetradecenoate (n-C14:1)_C14H25O2

011063
type: Reaction
product: 635648
reactant: 635624
is: http://identifiers.org/ec-code/2.3.1.50
is: ENSECAG00000020998.1
reactant: 635612
fast: false
reactant: 635600
is: ENSECAG00000021294.1
reversible: false
product: 635660
notes: R_SERPT subsystem: Sphingolipid Metabolism R_SERPT equation: [c] : h + pmtcoa + ser-L --> 3dsphgn + co2 + coa
product: 635636
name: serine C-palmitoyltransferase

635648
type: SpeciesReference
stoichiometry: 1.0
species: 592269

635624
type: SpeciesReference
stoichiometry: 1.0
species: 599531

635612
type: SpeciesReference
stoichiometry: 1.0
species: 607558

607558
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S

635600
type: SpeciesReference
stoichiometry: 1.0
species: 609352

635660
type: SpeciesReference
stoichiometry: 1.0
species: 585610

585610
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Dehydrosphinganine_C18H38NO2

635636
type: SpeciesReference
stoichiometry: 1.0
species: 592342

595144
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dolichyl beta-D-glucosyl phosphate, human uterine homolog_C1085H1780O90P10

609617
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO

014899
type: Reaction
reversible: false
notes: R_GLCNACPT_U subsystem: N-Glycan Biosynthesis R_GLCNACPT_U equation: [c] : (0.1) dolp_U + uacgam --> (0.1) naglc2p_U + ump R_GLCNACPT_L subsystem: N-Glycan Biosynthesis R_GLCNACPT_L equation: [c] : (0.1) dolp_L + uacgam --> (0.1) naglc2p_L + ump
reactant: 670614
reactant: 670589
product: 670638
reactant: 670602
is: ENSECAG00000013966.1
fast: false
is: http://identifiers.org/ec-code/2.7.8.15
product: 670650
product: 670626

670614
type: SpeciesReference
stoichiometry: 2.0
species: 611369

611369
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341

670589
type: SpeciesReference
stoichiometry: 1.0
species: 595218

595218
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dolichol phosphate, human liver homolog_C1080H1758O40P10

670638
type: SpeciesReference
stoichiometry: 2.0
species: 611660

670602
type: SpeciesReference
stoichiometry: 1.0
species: 595242

595242
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dolichol phosphate, human uterine homolog_C1025H1670O40P10

670650
type: SpeciesReference
stoichiometry: 1.0
species: 605503

605503
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-Acetyl-D-glucosaminyldiphosphodolichol, human liver homolog_C1160H1898N10O120P20

670626
type: SpeciesReference
stoichiometry: 1.0
species: 605515

588905
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: _3',8'-LD1_C66H111N4O38FULLRCO

014116
type: Reaction
reversible: true
product: 663301
reactant: 663265
product: 663289
is: ENSECAG00000000096.1
is: ENSECAG00000014112.1
notes: R_PIt8 subsystem: Transport, Extracellular R_PIt8 equation: (1.5) na1[e] + pi[e] <==> (1.5) na1[c] + pi[c]
reactant: 663277
fast: false
name: phosphate transport in/out via Na+ symporter

663301
type: SpeciesReference
stoichiometry: 1.5
species: 605187

663265
type: SpeciesReference
stoichiometry: 1.5
species: 605200

663289
type: SpeciesReference
stoichiometry: 1.0
species: 607462

663277
type: SpeciesReference
stoichiometry: 1.0
species: 607474

585029
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate_C13H15N4O12P

009866
type: Reaction
product: 624374
product: 624567
product: 624471
reactant: 623951
reactant: 623963
product: 624555
reactant: 624131
product: 624615
reactant: 624071
reactant: 624119
reactant: 624083
reactant: 623890
product: 624603
reactant: 624059
product: 624639
product: 624362
reactant: 624204
reactant: 624216
reactant: 623866
reactant: 624241
product: 624301
reversible: false
product: 624627
product: 624543
product: 624411
product: 624350
is: ENSECAG00000022130.1
product: 624531
reactant: 623999
product: 624459
product: 624447
reactant: 623902
reactant: 624023
reactant: 623927
notes: R_HEXCCPT2 subsystem: Carnitine shuttle R_HEXCCPT2 equation: [m] : coa + hexccrn --> crn + hexccoa R_C181CPT2 subsystem: Carnitine shuttle R_C181CPT2 equation: [m] : coa + odecrn --> crn + odecoa R_C160CPT2 subsystem: Carnitine shuttle R_C160CPT2 equation: [m] : coa + pmtcrn --> crn + pmtcoa R_RTOTALCRNCPT2 subsystem: Carnitine shuttle R_RTOTALCRNCPT2 equation: [m] : Rtotalcrn + coa --> Rtotalcoa + crn R_RTOTAL2CRNCPT2 subsystem: Carnitine shuttle R_RTOTAL2CRNCPT2 equation: [m] : Rtotal2crn + coa --> Rtotal2coa + crn R_VACCCPT2 subsystem: Carnitine shuttle R_VACCCPT2 equation: [m] : coa + vacccrn --> crn + vacccoa R_EICOSTETCPT2 subsystem: Carnitine shuttle R_EICOSTETCPT2 equation: [m] : coa + eicostetcrn --> crn + eicostetcoa R_TTDCPT2 subsystem: Carnitine shuttle R_TTDCPT2 equation: [m] : coa + ttdcrn --> crn + tdcoa R_PTDCACRNCPT2 subsystem: Carnitine shuttle R_PTDCACRNCPT2 equation: [m] : coa + ptdcacrn --> crn + ptdcacoa R_LGNCCPT2 subsystem: Carnitine shuttle R_LGNCCPT2 equation: [m] : coa + lgnccrn --> crn + lgnccoa R_C226CPT2 subsystem: Carnitine shuttle R_C226CPT2 equation: [m] : c226crn + coa --> c226coa + crn R_C161CPT22 subsystem: Carnitine shuttle R_C161CPT22 equation: [m] : coa + hdd2crn --> crn + hdd2coa R_DLNLCGCPT2 subsystem: Carnitine shuttle R_DLNLCGCPT2 equation: [m] : coa + dlnlcgcrn --> crn + dlnlcgcoa R_LNLCCPT2 subsystem: Carnitine shuttle R_LNLCCPT2 equation: [m] : coa + lnlccrn --> crn + lnlccoa R_CLPNDCPT2 subsystem: Carnitine shuttle R_CLPNDCPT2 equation: [m] : clpndcrn + coa --> clpndcoa + crn R_DCSPTN1CPT2 subsystem: Carnitine shuttle R_DCSPTN1CPT2 equation: [m] : coa + dcsptn1crn --> crn + dcsptn1coa R_HPDCACRNCPT2 subsystem: Carnitine shuttle R_HPDCACRNCPT2 equation: [m] : coa + hpdcacrn --> crn + hpdcacoa R_LNELDCCPT2 subsystem: Carnitine shuttle R_LNELDCCPT2 equation: [m] : coa + lneldccrn --> crn + lneldccoa R_STRDNCCPT2 subsystem: Carnitine shuttle R_STRDNCCPT2 equation: [m] : coa + strdnccrn --> crn + strdnccoa R_NRVNCCPT2 subsys…
product: 624519
product: 624338
reactant: 624143
reactant: 624180
reactant: 623975
product: 624435
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initial concentration: NaN
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name: Phosphoenolpyruvate_C3H2O6P

693182
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species: 588869

588869
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: N-Acetyl-D-mannosamine 6-phosphate_C8H14NO9P

693243
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species: 607462

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stoichiometry: 1.0
species: 588965

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type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: N-Acetylneuraminate 9-phosphate_C11H17NO12P

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species: 601383

601383
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _2-keto-3-deoxy-D-glycero-D-galactononic acid 9-phosphate_C9H14O12P

010580
type: Reaction
fast: false
is: ENSECAG00000013273.1
reactant: 631293
notes: R_TREHe subsystem: Starch and Sucrose Metabolism R_TREHe equation: [e] : h2o + tre --> (2) glc-D
reactant: 631281
reversible: false
name: alpha,alpha-trehalase
is: http://identifiers.org/ec-code/3.2.1.28
product: 631305

631293
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species: 599433

631281
type: SpeciesReference
stoichiometry: 1.0
species: 611042

611042
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constant: false
boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Trehalose_C12H22O11

631305
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species: 598109

018178
type: Reaction
reactant: 702604
product: 702640
reversible: true
notes: R_2OXOADPTm subsystem: Tryptophan metabolism R_2OXOADPTm equation: _2oxoadp[c] + akg[m] <==> 2oxoadp[m] + akg[c] R_2AMADPTm subsystem: Lysine Metabolism R_2AMADPTm equation: L2aadp[c] + akg[m] <==> L2aadp[m] + akg[c]
reactant: 702580
product: 702616
product: 702628
is: ENSECAG00000002597.1
fast: false
reactant: 702592

702604
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species: 589712

702640
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species: 589688

702580
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species: 585307

585307
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _2-Oxoadipate_C6H6O5

702616
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species: 587574

587574
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: L-2-Aminoadipate_C6H10NO4

702628
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species: 585319

702592
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species: 587562

587562
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constant: false
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initial concentration: NaN
initial amount: NaN
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name: L-2-Aminoadipate_C6H10NO4

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: N-Acetyl-L-aspartate_C6H7NO5

607388
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Phenylpyruvate_C9H7O3

016331
type: Reaction
is: ENSECAG00000014152.1
product: 686856
reversible: true
reactant: 686832
fast: false
name: _11-beta-hydroxysteroid dehydrogenase type 2
notes: R_HSD11B2r subsystem: Steroid Metabolism R_HSD11B2r equation: [r] : cortsn + h + nadh <==> crtsl + nad
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reactant: 686819
reactant: 686807

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species: 605296

605296
type: Species
constant: false
boundary condition: false
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initial concentration: NaN
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name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

686832
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species: 592499

592499
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
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name: Cortisone_C21H28O5

686844
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species: 592704

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Cortisol_C21H30O5

686819
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species: 599605

686807
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species: 605346

605346
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boundary condition: false
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initial concentration: NaN
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in compartment: 584353
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

591893
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initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Cholesterol_C27H46O

607147
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2

585500
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: _3',5'-Cyclic GMP_C10H11N5O7P

598675
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
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in compartment: 584341
name: glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]})_C66H111O56X

586871
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: pentaglutamyl folate (DHF)_C39H43N11O18

015079
type: Reaction
reversible: false
reactant: 672134
product: 672459
reactant: 672182
reactant: 672231
product: 672411
reactant: 672255
product: 672435
product: 672423
notes: R_3MOXTYROX subsystem: Tyrosine metabolism R_3MOXTYROX equation: [c] : 3moxtyr + h2o + o2 --> 3mox4hpac + h2o2 + nh4 R_MAOLNOR subsystem: Tyrosine metabolism R_MAOLNOR equation: [c] : h2o + normete-L + o2 --> 3m4hpga + h2o2 + nh4 R_APRTO2 subsystem: Arginine and Proline Metabolism R_APRTO2 equation: [c] : aprut + h2o + o2 --> h2o2 + n4abutn + nh4 R_42A12BOOX subsystem: Tyrosine metabolism R_42A12BOOX equation: [c] : dopa + h2o + o2 --> 34dhpac + h2o2 + nh4 R_PEAMNO subsystem: Phenylalanine metabolism R_PEAMNO equation: [c] : h2o + o2 + peamn --> h2o2 + nh4 + pacald R_MACOXO subsystem: Histidine Metabolism R_MACOXO equation: [c] : 3mldz + h2o + nad --> 3mlda + (2) h + nadh R_3HXKYNOXDA subsystem: Tryptophan metabolism R_3HXKYNOXDA equation: [c] : 3hxkynam + o2 --> 48dhoxquin + h2o2 + nh4 R_41R2A1H12BOOX subsystem: Tyrosine metabolism R_41R2A1H12BOOX equation: [c] : h2o + nrpphr + o2 --> 34dhmald + h2o2 + nh4 R_TRYPTAOX subsystem: Tryptophan metabolism R_TRYPTAOX equation: [c] : h2o + o2 + trypta --> h2o2 + id3acald + nh4 R_5HXKYNOXDA subsystem: Tryptophan metabolism R_5HXKYNOXDA equation: [c] : 5hxkynam + o2 --> 46dhoxquin + h2o2 + nh4 R_TYROXDAc subsystem: Tyrosine metabolism R_TYROXDAc equation: [c] : h2o + o2 + tym --> 4hoxpacd + h2o2 + nh4 R_5HOXINOXDA subsystem: Tryptophan metabolism R_5HOXINOXDA equation: [c] : h2o + o2 + srtn --> 5hoxindact + h2o2 + nh4 R_41R1H2MAE12BOOX subsystem: Tyrosine metabolism R_41R1H2MAE12BOOX equation: [c] : adrnl + h2o + o2 --> 34dhmald + h2o2 + mma
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reactant: 672095
reactant: 672121
product: 672363
product: 672291
reactant: 672083
reactant: 672206
product: 672387
is: http://identifiers.org/ec-code/1.2.1.5
product: 672375
product: 672279
product: 672399
reactant: 672146
is: http://identifiers.org/ec-code/1.4.3.6
reactant: 672170
is: ENSECAG00000000132.1
product: 672327
product: 672339
product: 672351
reactant: 672071
reactant: 672219
reactant: 672108
product: 672303
is: http://identifiers.org/ec-code/1.4.3.4
reactant: 672243
product: 672315
reactant: 672158
reactant: 672194
product: 672267
fast: false

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species: 611114

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species: 605322

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type: SpeciesReference
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species: 587056

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type: SpeciesReference
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species: 599421

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type: SpeciesReference
stoichiometry: 1.0
species: 586228

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type: Species
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initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _4,8-Dihydroxyquinoline_C9H7NO2

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species: 590319

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type: SpeciesReference
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species: 585367

585367
type: Species
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initial concentration: NaN
initial amount: NaN
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name: _3,4-Dihydroxymandelaldehyde_C8H8O4

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species: 599531

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species: 586216

586216
type: Species
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initial concentration: NaN
initial amount: NaN
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name: _4,6-Dihydroxyquinoline_C9H7NO2

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species: 605792

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species: 589446

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type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: Adrenaline_C9H14NO3

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species: 586960

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type: SpeciesReference
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species: 586412

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type: Species
constant: false
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initial concentration: NaN
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name: _4-Hydroxyphenylacetaldehyde_C8H8O2

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species: 585876

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species: 585803

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type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: _3-Hydroxykynurenamine_C9H13N2O2

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species: 599349

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type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Hydrogen peroxide_H2O2

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species: 606636

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species: 605151

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type: Species
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boundary condition: false
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initial concentration: NaN
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name: N4-Acetylaminobutanal_C6H11NO2

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species: 600936

600936
type: Species
constant: false
boundary condition: false
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initial concentration: NaN
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name: Indole-3-acetaldehyde_C10H9NO

672146
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species: 611309

611309
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Tyramine_C8H12NO

672170
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species: 607159

607159
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Phenethylamine_C8H12N

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species: 604898

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type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Methylamine_C1H6N

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species: 585864

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type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: _3-Methylimidazoleacetic acid_C6H7N2O2

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species: 585828

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type: Species
constant: false
boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Methoxy-4-hydroxyphenylglycolaldehyde_C9H10O4

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species: 605816

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type: SpeciesReference
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species: 595266

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type: SpeciesReference
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species: 605248

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species: 585403

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type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3,4-Dihydroxyphenylacetaldehyde_C8H8O3

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species: 605960

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type: Species
constant: false
boundary condition: false
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initial concentration: NaN
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in compartment: 584341
name: O2_O2

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species: 605563

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type: SpeciesReference
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species: 585962

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type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Methoxytyramine_C9H14NO2

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species: 609715

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type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Serotonin_C10H13N2O

672267
type: SpeciesReference
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species: 585950

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type: Species
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has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Methoxy-4-hydroxyphenylacetaldehyde_C9H10O3

014430
type: Reaction
reversible: false
fast: false
is: ENSECAG00000003602.1
reactant: 667204
product: 667252
notes: R_SO4HCOtex subsystem: Transport, Extracellular R_SO4HCOtex equation: (2) hco3[c] + so4[e] --> (2) hco3[e] + so4[c] R_CLHCOtex subsystem: Transport, Extracellular R_CLHCOtex equation: cl[e] + (2) hco3[c] --> cl[c] + (2) hco3[e]
product: 667240
is: ENSECAG00000015837.1
is: ENSECAG00000000493.1
product: 667264
reactant: 667216
reactant: 667228

667204
type: SpeciesReference
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species: 599689

667252
type: SpeciesReference
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species: 609472

609472
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Sulfate_O4S

667240
type: SpeciesReference
stoichiometry: 1.0
species: 592027

667264
type: SpeciesReference
stoichiometry: 4.0
species: 599701

667216
type: SpeciesReference
stoichiometry: 1.0
species: 609485

667228
type: SpeciesReference
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species: 592039

012935
type: Reaction
notes: R_MM5bg subsystem: N-Glycan Biosynthesis R_MM5bg equation: [g] : h2o + m5masnB1 --> m4masn + man R_MM7Cbg subsystem: N-Glycan Biosynthesis R_MM7Cbg equation: [g] : h2o + m7masnC --> m6masnC + man R_MM6B2g subsystem: N-Glycan Biosynthesis R_MM6B2g equation: [g] : h2o + m6masnB2 --> m5masnB2 + man R_MM6bg subsystem: N-Glycan Biosynthesis R_MM6bg equation: [g] : h2o + m6masnC --> m5masnC + man R_MM8Ag subsystem: N-Glycan Biosynthesis R_MM8Ag equation: [g] : h2o + m8masn --> m7masnA + man R_MM6ag subsystem: N-Glycan Biosynthesis R_MM6ag equation: [g] : h2o + m6masnA --> m5masnC + man R_MM8Cg subsystem: N-Glycan Biosynthesis R_MM8Cg equation: [g] : h2o + m8masn --> m7masnC + man R_MM7Cag subsystem: N-Glycan Biosynthesis R_MM7Cag equation: [g] : h2o + m7masnA --> m6masnC + man R_MM6B1ag subsystem: N-Glycan Biosynthesis R_MM6B1ag equation: [g] : h2o + m6masnB1 --> m5masnB1 + man R_MM7Ag subsystem: N-Glycan Biosynthesis R_MM7Ag equation: [g] : h2o + m7masnA --> m6masnA + man R_MM7B2g subsystem: N-Glycan Biosynthesis R_MM7B2g equation: [g] : h2o + m7masnB --> m6masnB2 + man R_MM6B1bg subsystem: N-Glycan Biosynthesis R_MM6B1bg equation: [g] : h2o + m6masnB2 --> m5masnB1 + man R_MM5ag subsystem: N-Glycan Biosynthesis R_MM5ag equation: [g] : h2o + m5masnC --> m4masn + man R_MM5cg subsystem: N-Glycan Biosynthesis R_MM5cg equation: [g] : h2o + m5masnB2 --> m4masn + man R_MM7B1g subsystem: N-Glycan Biosynthesis R_MM7B1g equation: [g] : h2o + m7masnB --> m6masnB1 + man
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reactant: 651722
product: 651854
product: 651914
product: 651950
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reactant: 651758
reactant: 651734
is: ENSECAG00000014244.1
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reactant: 651806
reactant: 651782
reactant: 651710
product: 651926
reactant: 651794
reactant: 651770
product: 651866
reactant: 651686
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reversible: false
product: 651902
is: http://identifiers.org/ec-code/3.2.1.113
product: 651890
product: 651878
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type: Species
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species: 604012

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species: 603902

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species: 603842

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species: 604355

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name: D-Mannose_C6H12O6

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species: 604051

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species: 603974

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type: SpeciesReference
stoichiometry: 1.0
species: 603854

651902
type: SpeciesReference
stoichiometry: 1.0
species: 603974

651890
type: SpeciesReference
stoichiometry: 2.0
species: 603938

651878
type: SpeciesReference
stoichiometry: 1.0
species: 603914

603914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X

651938
type: SpeciesReference
stoichiometry: 2.0
species: 603842

651746
type: SpeciesReference
stoichiometry: 1.0
species: 603914

010122
type: Reaction
product: 627124
product: 627112
reversible: true
is: ENSECAG00000020313.1
fast: false
reactant: 627064
notes: R_PHEtec subsystem: Transport, Extracellular R_PHEtec equation: phe-L[e] <==> phe-L[c] R_TYRt subsystem: Transport, Extracellular R_TYRt equation: tyr-L[e] <==> tyr-L[c] R_TRPt subsystem: Transport, Extracellular R_TRPt equation: trp-L[e] <==> trp-L[c] R_34DHPHEt subsystem: Transport, Extracellular R_34DHPHEt equation: _34dhphe[e] <==> 34dhphe[c]
reactant: 627052
reactant: 627076
reactant: 627040
product: 627088
product: 627100

627124
type: SpeciesReference
stoichiometry: 1.0
species: 607292

627112
type: SpeciesReference
stoichiometry: 1.0
species: 611090

627064
type: SpeciesReference
stoichiometry: 1.0
species: 611345

627052
type: SpeciesReference
stoichiometry: 1.0
species: 585439

585439
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: _3,4-Dihydroxy-L-phenylalanine_C9H11NO4

627076
type: SpeciesReference
stoichiometry: 1.0
species: 607304

627040
type: SpeciesReference
stoichiometry: 1.0
species: 611102

627088
type: SpeciesReference
stoichiometry: 1.0
species: 585427

585427
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3,4-Dihydroxy-L-phenylalanine_C9H11NO4

627100
type: SpeciesReference
stoichiometry: 1.0
species: 611333

589785
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Alanine_C3H7NO2

606455
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: D-Ornithine_C5H13N2O2

019405
type: Reaction
product: 715864
reversible: false
reactant: 715852
is: http://identifiers.org/ec-code/4.1.3.4
fast: false
is: ENSECAG00000025131.1
product: 715876
product: 715889
product: 715901
reactant: 715840
notes: R_HMGLx subsystem: Cholesterol Metabolism R_HMGLx equation: [x] : hmgcoa --> acac + accoa R_HMGLm subsystem: Cholesterol Metabolism R_HMGLm equation: [m] : hmgcoa --> acac + accoa

715864
type: SpeciesReference
stoichiometry: 1.0
species: 588336

715852
type: SpeciesReference
stoichiometry: 1.0
species: 600125

600125
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425

715876
type: SpeciesReference
stoichiometry: 1.0
species: 588432

715889
type: SpeciesReference
stoichiometry: 1.0
species: 588348

588348
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Acetoacetate_C4H5O3

715901
type: SpeciesReference
stoichiometry: 1.0
species: 588470

715840
type: SpeciesReference
stoichiometry: 1.0
species: 600099

600099
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401

585634
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425

016087
type: Reaction
product: 684030
reactant: 683934
product: 684018
product: 684042
reactant: 683982
is: ENSECAG00000023798.1
product: 684006
is: http://identifiers.org/ec-code/2.4.99.4
notes: R_S23T4g subsystem: Keratan sulfate biosynthesis R_S23T4g equation: [g] : cmpacna + ksii_core4_pre1 --> cmp + h + ksii_core4_pre2 R_ST3GAL21g subsystem: Sphingolipid Metabolism R_ST3GAL21g equation: [g] : cmpacna + ga1_hs --> cmp + gm1b_hs + h R_ST3GAL22g subsystem: Sphingolipid Metabolism R_ST3GAL22g equation: [g] : cmpacna + gm1_hs --> cmp + gd1a_hs + h R_SIAT4Bg subsystem: Sphingolipid Metabolism R_SIAT4Bg equation: [g] : cmpacna + galgbside_hs --> acngalgbside_hs + cmp + h R_S23T2g subsystem: Keratan sulfate biosynthesis R_S23T2g equation: [g] : cmpacna + core2 --> cmp + h + ksii_core2_pre1 R_ST3GAL23g subsystem: Sphingolipid Metabolism R_ST3GAL23g equation: [g] : cmpacna + gd1b_hs --> cmp + gt1b_hs + h
reactant: 683994
reactant: 683946
fast: false
product: 684078
product: 684054
reactant: 683970
reactant: 683922
reactant: 683958
reversible: false
product: 684066
product: 684090

684030
type: SpeciesReference
stoichiometry: 1.0
species: 589013

589013
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: sialyl galactosylgloboside (homo sapiens)_C61H105N3O35FULLRCO

683934
type: SpeciesReference
stoichiometry: 1.0
species: 598736

598736
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: ganglioside GM1 (homo sapiens)_C55H95N3O30FULLRCO

684018
type: SpeciesReference
stoichiometry: 6.0
species: 599556

684042
type: SpeciesReference
stoichiometry: 1.0
species: 598760

683982
type: SpeciesReference
stoichiometry: 1.0
species: 597868

597868
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GD1b (homo sapiens)_C66H111N4O38FULLRCO

684006
type: SpeciesReference
stoichiometry: 1.0
species: 597832

597832
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GD1a (homo sapiens)_C66H111N4O38FULLRCO

683994
type: SpeciesReference
stoichiometry: 1.0
species: 592438

683946
type: SpeciesReference
stoichiometry: 6.0
species: 592220

684078
type: SpeciesReference
stoichiometry: 6.0
species: 592172

684054
type: SpeciesReference
stoichiometry: 1.0
species: 602518

683970
type: SpeciesReference
stoichiometry: 1.0
species: 597336

597336
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GA1 (homo sapiens)_C44H79N2O22FULLRCO

683922
type: SpeciesReference
stoichiometry: 1.0
species: 597602

597602
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: galactosylgloboside (homo sapiens)_C50H89N2O27FULLRCO

683958
type: SpeciesReference
stoichiometry: 1.0
species: 602712

684066
type: SpeciesReference
stoichiometry: 1.0
species: 602724

684090
type: SpeciesReference
stoichiometry: 1.0
species: 599096

599096
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GT1b (homo sapiens)_C77H127N5O46FULLRCO

011438
type: Reaction
is: ENSECAG00000013644.1
notes: R_DNAMTSEn subsystem: Selenoamino acid metabolism R_DNAMTSEn equation: [n] : dna + seasmet --> dna5mtc + h + seahcys R_DNAMTn subsystem: Methionine Metabolism R_DNAMTn equation: [n] : amet + dna --> ahcys + dna5mtc + h
reactant: 638224
is: ENSECAG00000012102.1
product: 638248
is: ENSECAG00000025086.1
fast: false
product: 638260
product: 638272
product: 638236
is: http://identifiers.org/ec-code/2.1.1.37
reactant: 638200
reversible: false
reactant: 638212

638224
type: SpeciesReference
stoichiometry: 1.0
species: 609220

609220
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: Se-Adenosylselenomethionine_C15H23N6O5Se

638248
type: SpeciesReference
stoichiometry: 2.0
species: 599593

599593
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: H+_H

638260
type: SpeciesReference
stoichiometry: 1.0
species: 609196

638272
type: SpeciesReference
stoichiometry: 1.0
species: 589579

589579
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

638236
type: SpeciesReference
stoichiometry: 2.0
species: 595036

595036
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: DNA 5-methylcytosine_C11H19O8PR2

638200
type: SpeciesReference
stoichiometry: 2.0
species: 595048

595048
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: DNA_C10H17O8PR2

638212
type: SpeciesReference
stoichiometry: 1.0
species: 590005

590005
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: S-Adenosyl-L-methionine_C15H23N6O5S

009975
type: Reaction
reactant: 625403
product: 625451
fast: false
product: 625463
product: 625439
reversible: false
product: 625427
notes: R_HSD3B7 subsystem: Bile Acid Biosynthesis R_HSD3B7 equation: [r] : nad + xol7a --> h + nadh + xol7aone R_HSD3B7P subsystem: Bile Acid Biosynthesis R_HSD3B7P equation: [r] : nadp + xol7a --> h + nadph + xol7aone
reactant: 625391
reactant: 625415
is: ENSECAG00000011133.1

625403
type: SpeciesReference
stoichiometry: 1.0
species: 605418

605418
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

625451
type: SpeciesReference
stoichiometry: 1.0
species: 605479

605479
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

625463
type: SpeciesReference
stoichiometry: 2.0
species: 599605

625439
type: SpeciesReference
stoichiometry: 1.0
species: 605346

625427
type: SpeciesReference
stoichiometry: 2.0
species: 612301

612301
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _7alpha-Hydroxycholest-4-en-3-one_C27H44O2

625391
type: SpeciesReference
stoichiometry: 2.0
species: 612216

612216
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _7 alpha-Hydroxycholesterol_C27H46O2

625415
type: SpeciesReference
stoichiometry: 1.0
species: 605296

607232
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Perillic acid_C10H13O2

610187
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Tetradecanoyl-CoA (n-C14:0CoA)_C35H58N7O17P3S

605551
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-Formylanthranilate_C8H6NO3

586544
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _4-Methylzymosterol intermediate 2_C28H44O

607958
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Pregnenolone_C21H32O2

010845
type: Reaction
product: 633935
reversible: true
name: methylcrotonoyl-CoA carboxylase, mitochondrial
is: ENSECAG00000010213.1
notes: R_MCCCrm subsystem: Valine, Leucine, and Isoleucine Metabolism R_MCCCrm equation: [m] : 3mb2coa + atp + hco3 <==> 3mgcoa + adp + h + pi
product: 633923
is: ENSECAG00000008214.1
is: http://identifiers.org/ec-code/6.4.1.4
reactant: 633887
reactant: 633875
product: 633947
product: 633911
fast: false
reactant: 633899

633935
type: SpeciesReference
stoichiometry: 1.0
species: 585852

585852
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _3-Methylglutaconyl-CoA_C27H37N7O19P3S

633923
type: SpeciesReference
stoichiometry: 1.0
species: 589230

589230
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: ADP_C10H12N5O10P2

633887
type: SpeciesReference
stoichiometry: 1.0
species: 585840

585840
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _3-Methylbut-2-enoyl-CoA_C26H38N7O17P3S

633875
type: SpeciesReference
stoichiometry: 1.0
species: 599713

633947
type: SpeciesReference
stoichiometry: 1.0
species: 599581

633911
type: SpeciesReference
stoichiometry: 1.0
species: 607510

607510
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Phosphate_HO4P

633899
type: SpeciesReference
stoichiometry: 1.0
species: 590751

590751
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: ATP_C10H12N5O13P3

590667
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: D-Aspartate_C4H6NO4

585464
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _3-(4-Hydroxyphenyl)pyruvate_C9H7O4

604826
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _1D-myo-Inositol 3-phosphate_C6H11O9P

018587
type: Reaction
product: 706318
reactant: 706306
notes: R_PHEMEt subsystem: Transport, Extracellular R_PHEMEt equation: pheme[e] --> pheme[c]
is: ENSECAG00000006826.1
fast: false
reversible: false
name: heme transport

706318
type: SpeciesReference
stoichiometry: 1.0
species: 607328

607328
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Protoheme_C34H30FeN4O4

706306
type: SpeciesReference
stoichiometry: 1.0
species: 607340

607340
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Protoheme_C34H30FeN4O4

603288
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: (R)-S-Lactoylglutathione_C13H20N3O8S

013211
type: Reaction
product: 654017
reversible: true
fast: false
is: ENSECAG00000011716.1
reactant: 653993
reactant: 653981
notes: R_FATP1t subsystem: Transport, Extracellular R_FATP1t equation: hdca[c] + na1[c] <==> hdca[e] + na1[e]
product: 654005
name: fatty acid electroneutral transport
is: ENSECAG00000015841.1

654017
type: SpeciesReference
stoichiometry: 1.0
species: 599761

599761
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Hexadecanoate (n-C16:0)_C16H31O2

653993
type: SpeciesReference
stoichiometry: 1.0
species: 605187

653981
type: SpeciesReference
stoichiometry: 1.0
species: 599749

599749
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Hexadecanoate (n-C16:0)_C16H31O2

654005
type: SpeciesReference
stoichiometry: 1.0
species: 605200

605804
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Naphthalene_C10H8

611018
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Reduced thioredoxin_XH2

591411
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Cob(I)alamin_C62H88CoN13O14P

603373
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Linoelaidyl carnitine_C25H45NO4

587272
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _6-Phospho-D-gluconate_C6H10O10P

604379
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: D-Mannose_C6H12O6

591125
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Biotin_C10H15N2O3S

016197
type: Reaction
is: http://identifiers.org/ec-code/1.1.1.204
is: ENSECAG00000000537.1
reactant: 685737
product: 685785
product: 685797
product: 685809
notes: R_XAO2x subsystem: Purine Catabolism R_XAO2x equation: [x] : h2o + hxan + o2 --> h2o2 + xan R_XAOx subsystem: Purine Catabolism R_XAOx equation: [x] : h2o + o2 + xan --> h2o2 + urate R_XANDp subsystem: Purine Catabolism R_XANDp equation: [x] : h2o + nad + xan --> h + nadh + urate
reactant: 685773
reactant: 685749
reversible: false
product: 685833
fast: false
is: ENSECAG00000014518.1
product: 685821
is: ENSECAG00000021671.1
reactant: 685725
reactant: 685761

685737
type: SpeciesReference
stoichiometry: 2.0
species: 606021

685785
type: SpeciesReference
stoichiometry: 1.0
species: 605358

685797
type: SpeciesReference
stoichiometry: 2.0
species: 611781

611781
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Urate_C5H4N4O3

685809
type: SpeciesReference
stoichiometry: 2.0
species: 599409

685773
type: SpeciesReference
stoichiometry: 2.0
species: 612143

612143
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Xanthine_C5H4N4O2

685749
type: SpeciesReference
stoichiometry: 1.0
species: 600828

685833
type: SpeciesReference
stoichiometry: 1.0
species: 599617

685821
type: SpeciesReference
stoichiometry: 1.0
species: 612143

685725
type: SpeciesReference
stoichiometry: 3.0
species: 599506

685761
type: SpeciesReference
stoichiometry: 1.0
species: 605309

010387
type: Reaction
reactant: 629459
product: 629617
product: 629569
reactant: 629472
notes: R_ACCOACm subsystem: Fatty Acid Metabolism R_ACCOACm equation: [m] : accoa + atp + hco3 --> adp + h + malcoa + pi R_ACCOAC subsystem: Fatty Acid Metabolism R_ACCOAC equation: [c] : accoa + atp + hco3 --> adp + h + malcoa + pi
product: 629605
product: 629593
product: 629532
product: 629557
reactant: 629496
product: 629581
is: ENSECAG00000015652.1
reactant: 629508
reactant: 629484
product: 629544
reversible: false
reactant: 629520
fast: false
is: http://identifiers.org/ec-code/6.4.1.2

629459
type: SpeciesReference
stoichiometry: 1.0
species: 599713

629617
type: SpeciesReference
stoichiometry: 1.0
species: 599581

629569
type: SpeciesReference
stoichiometry: 1.0
species: 589230

629472
type: SpeciesReference
stoichiometry: 1.0
species: 599689

629605
type: SpeciesReference
stoichiometry: 1.0
species: 599531

629593
type: SpeciesReference
stoichiometry: 1.0
species: 589206

629532
type: SpeciesReference
stoichiometry: 1.0
species: 604209

604209
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Malonyl-CoA_C24H33N7O19P3S

629557
type: SpeciesReference
stoichiometry: 1.0
species: 607510

629496
type: SpeciesReference
stoichiometry: 1.0
species: 588432

629581
type: SpeciesReference
stoichiometry: 1.0
species: 604197

629508
type: SpeciesReference
stoichiometry: 1.0
species: 590751

629484
type: SpeciesReference
stoichiometry: 1.0
species: 590727

629544
type: SpeciesReference
stoichiometry: 1.0
species: 607462

629520
type: SpeciesReference
stoichiometry: 1.0
species: 588408

591259
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
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in compartment: 584401

607777
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Diphosphate_HO7P2

610872
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N6,N6,N6-Trimethyl-L-lysine_C9H20N2O2

017769
type: Reaction
is: http://identifiers.org/ec-code/2.2.1.2
reversible: true
notes: R_TALA subsystem: Pentose Phosphate Pathway R_TALA equation: [c] : g3p + s7p <==> e4p + f6p
product: 699360
name: transaldolase
reactant: 699336
fast: false
reactant: 699324
product: 699348
is: ENSECAG00000011679.1

699360
type: SpeciesReference
stoichiometry: 1.0
species: 595714

699336
type: SpeciesReference
stoichiometry: 1.0
species: 597288

699324
type: SpeciesReference
stoichiometry: 1.0
species: 609088

699348
type: SpeciesReference
stoichiometry: 1.0
species: 596300

597892
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GD2 (homo sapiens)_C60H101N4O33FULLRCO

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initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Crotonoyl-CoA_C25H36N7O17P3S

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initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: pristanic acid_C19H37O2

011124
type: Reaction
reversible: false
reactant: 635950
product: 636022
product: 636010
product: 636035
product: 636072
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product: 636060
product: 636047
reactant: 635986
reactant: 635962
fast: false
is: http://identifiers.org/ec-code/1.17.4.1
is: ENSECAG00000007464.1
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reactant: 635998
reactant: 635974

635950
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species: 611006

611006
type: Species
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boundary condition: false
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initial concentration: NaN
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name: Reduced thioredoxin_XH2

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species: 595534

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type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: dUDP_C9H11N2O11P2

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species: 593656

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type: Species
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initial concentration: NaN
initial amount: NaN
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name: dADP_C10H12N5O9P2

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species: 610982

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type: Species
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initial concentration: NaN
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name: Oxidized thioredoxin_X

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species: 594227

636060
type: SpeciesReference
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species: 599421

636047
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species: 593839

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type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: dCDP_C9H12N3O10P2

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type: SpeciesReference
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species: 611393

611393
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: UDP_C9H11N2O12P2

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type: SpeciesReference
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species: 597940

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type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: GDP_C10H12N5O11P2

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type: SpeciesReference
stoichiometry: 1.0
species: 591483

591483
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: CDP_C9H12N3O11P2

635974
type: SpeciesReference
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species: 589206

594396
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Dihydroxyacetone phosphate_C3H5O6P

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type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Glutamine_C5H10N2O3

018827
type: Reaction
reactant: 710402
product: 710414
is: ENSECAG00000023055.1
name: glucosamine-6-phosphate deaminase
fast: false
is: ENSECAG00000016016.1
reactant: 710390
product: 710427
reversible: false
notes: R_G6PDA subsystem: Aminosugar Metabolism R_G6PDA equation: [c] : gam6p + h2o --> f6p + nh4
is: http://identifiers.org/ec-code/3.5.99.6

710402
type: SpeciesReference
stoichiometry: 1.0
species: 599421

710414
type: SpeciesReference
stoichiometry: 1.0
species: 605563

710390
type: SpeciesReference
stoichiometry: 1.0
species: 597698

710427
type: SpeciesReference
stoichiometry: 1.0
species: 596300

606239
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: octadecanoate (n-C18:0)_C18H35O2

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 38_C54H91N3O41

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type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: dUMP_C9H11N2O8P

586796
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate_C9H11N3O9P

601226
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Inosine_C10H12N4O5

009659
type: Reaction
notes: R_SFGTH subsystem: Tyrosine metabolism R_SFGTH equation: [c] : Sfglutth + h2o <==> for + gthrd + h
product: 622446
name: S-Formylglutathione hydralase
product: 622458
product: 622470
is: ENSECAG00000024350.1
reactant: 622422
reactant: 622434
is: http://identifiers.org/ec-code/3.1.2.12
reversible: true
fast: false

622446
type: SpeciesReference
stoichiometry: 1.0
species: 596612

622458
type: SpeciesReference
stoichiometry: 1.0
species: 599192

622470
type: SpeciesReference
stoichiometry: 1.0
species: 599531

622422
type: SpeciesReference
stoichiometry: 1.0
species: 588094

588094
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: S-Formylglutathione_C11H16N3O7S

622434
type: SpeciesReference
stoichiometry: 1.0
species: 599421

ORG:
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n:
  given: Michaël
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008632
type: Reaction
product: 613612
notes: R_TRDRm subsystem: Nucleotides R_TRDRm equation: [m] : h + nadph + trdox --> nadp + trdrd
name: thioredoxin reductase (NADPH)
product: 613600
reactant: 613576
is: ENSECAG00000022090.1
reactant: 613588
fast: false
reactant: 613564
is: http://identifiers.org/ec-code/1.8.1.9
reversible: false

613612
type: SpeciesReference
stoichiometry: 1.0
species: 605394

613600
type: SpeciesReference
stoichiometry: 1.0
species: 611018

613576
type: SpeciesReference
stoichiometry: 1.0
species: 599581

613588
type: SpeciesReference
stoichiometry: 1.0
species: 610994

610994
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Oxidized thioredoxin_X

613564
type: SpeciesReference
stoichiometry: 1.0
species: 605454

011859
type: Reaction
is: http://identifiers.org/ec-code/2.8.2.23
is: ENSECAG00000025171.1
reactant: 641885
name: heparin-glucosamine 3-O-sulfotransferase
product: 641933
fast: false
product: 641909
product: 641921
reactant: 641897
notes: R_S3T3g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T3g equation: [g] : hs_pre15 + paps --> h + hspg + pap
reversible: false
is: ENSECAG00000000862.1

641885
type: SpeciesReference
stoichiometry: 1.0
species: 600647

600647
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: heparan sulfate, precursor 15_C79H114N5O98S11X

641933
type: SpeciesReference
stoichiometry: 1.0
species: 606929

606929
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Adenosine 3',5'-bisphosphate_C10H11N5O10P2

641909
type: SpeciesReference
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species: 599556

641921
type: SpeciesReference
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species: 600767

600767
type: Species
constant: false
boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: heparan sulfate proteoglycan_C79H113N5O101S12X

641897
type: SpeciesReference
stoichiometry: 1.0
species: 606953

606953
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: _3'-Phosphoadenylyl sulfate_C10H11N5O13P2S

601311
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: ITP_C10H11N4O14P3

591857
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Cholesterol_C27H46O

611647
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: UDP-D-xylose_C14H20N2O16P2

604584
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5,10-Methenyltetrahydrofolate_C20H20N7O6

590138
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Androstenedione_C19H26O2

019200
type: Reaction
product: 714296
name: GDPFuc Golgi transport via CMP antiport
notes: R_GDPFUCtg subsystem: Transport, Golgi Apparatus R_GDPFUCtg equation: gdpfuc[c] + gmp[g] <==> gdpfuc[g] + gmp[c]
reactant: 714272
is: ENSECAG00000000770.1
fast: false
reversible: true
product: 714284
reactant: 714260

714296
type: SpeciesReference
stoichiometry: 1.0
species: 598025

598025
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GDP-L-fucose_C16H23N5O15P2

714272
type: SpeciesReference
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species: 598832

714284
type: SpeciesReference
stoichiometry: 1.0
species: 598808

714260
type: SpeciesReference
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species: 598013

598013
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: GDP-L-fucose_C16H23N5O15P2

018383
type: Reaction
reactant: 704156
notes: R_PCm subsystem: Pyruvate Metabolism R_PCm equation: [m] : atp + hco3 + pyr --> adp + h + oaa + pi
is: http://identifiers.org/ec-code/6.4.1.1
reactant: 704168
name: pyruvate carboxylase
product: 704204
fast: false
product: 704216
reversible: false
is: ENSECAG00000024887.1
reactant: 704180
product: 704228
product: 704192

704156
type: SpeciesReference
stoichiometry: 1.0
species: 599713

704168
type: SpeciesReference
stoichiometry: 1.0
species: 590751

704204
type: SpeciesReference
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species: 607510

704216
type: SpeciesReference
stoichiometry: 1.0
species: 589230

704180
type: SpeciesReference
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species: 608665

704228
type: SpeciesReference
stoichiometry: 1.0
species: 599581

704192
type: SpeciesReference
stoichiometry: 1.0
species: 606106

606106
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Oxaloacetate_C4H2O5

012403
type: Reaction
reactant: 646979
product: 647016
is: ENSECAG00000000186.1
product: 647004
product: 647028
reactant: 646991
fast: false
reversible: false
notes: R_DHCRD1 subsystem: Sphingolipid Metabolism R_DHCRD1 equation: [c] : dhcrm_hs + nadp --> crm_hs + h + nadph R_DHCRD2 subsystem: Sphingolipid Metabolism R_DHCRD2 equation: [c] : dhcrm_hs + fad --> crm_hs + fadh2
product: 647040
reactant: 646967

646979
type: SpeciesReference
stoichiometry: 2.0
species: 594516

594516
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: dihydroceramide (homo sapiens)_C18H38NO2FULLRCO

647016
type: SpeciesReference
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species: 592571

592571
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: ceramide (homo sapiens)_C18H36NO2FULLRCO

647004
type: SpeciesReference
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species: 596360

596360
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

647028
type: SpeciesReference
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species: 599531

646991
type: SpeciesReference
stoichiometry: 1.0
species: 605370

647040
type: SpeciesReference
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species: 605442

646967
type: SpeciesReference
stoichiometry: 1.0
species: 596312

596312
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

589555
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

016862
type: Reaction
reactant: 690550
reversible: false
reactant: 690610
reactant: 690586
notes: R_SPODMn subsystem: ROS Detoxification R_SPODMn equation: [n] : (2) h + (2) o2s --> h2o2 + o2 R_SPODMx subsystem: ROS Detoxification R_SPODMx equation: [x] : (2) h + (2) o2s --> h2o2 + o2 R_SPODM subsystem: ROS Detoxification R_SPODM equation: [c] : (2) h + (2) o2s --> h2o2 + o2
product: 690646
product: 690622
reactant: 690598
reactant: 690574
product: 690658
is: http://identifiers.org/ec-code/1.15.1.1
product: 690634
fast: false
is: ENSECAG00000008958.1
product: 690670
product: 690682
reactant: 690562

690550
type: SpeciesReference
stoichiometry: 2.0
species: 606070

606070
type: Species
constant: false
boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: Superoxide anion_O2

690610
type: SpeciesReference
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species: 599531

690586
type: SpeciesReference
stoichiometry: 2.0
species: 606034

606034
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Superoxide anion_O2

690646
type: SpeciesReference
stoichiometry: 1.0
species: 605996

605996
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: O2_O2

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species: 606021

690598
type: SpeciesReference
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species: 599617

690574
type: SpeciesReference
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species: 599593

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type: SpeciesReference
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species: 599409

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species: 599397

599397
type: Species
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initial concentration: NaN
initial amount: NaN
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name: Hydrogen peroxide_H2O2

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type: SpeciesReference
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species: 599349

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type: SpeciesReference
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species: 605960

690562
type: SpeciesReference
stoichiometry: 2.0
species: 606082

606082
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Superoxide anion_O2

601251
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Isopentenyl diphosphate_C5H9O7P2

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: dCTP_C9H12N3O13P3

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 3_C37H52NO43S4X

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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: Indole-3-acetaldehyde_C10H9NO

008728
type: Reaction
product: 614362
product: 614350
reactant: 614301
reversible: false
notes: R_PLA2_2 subsystem: Glycerophospholipid Metabolism R_PLA2_2 equation: [c] : h2o + pchol_hs --> Rtotal2 + h + lpchol_hs R_PLA2_2e subsystem: Glycerophospholipid Metabolism R_PLA2_2e equation: [e] : h2o + pchol_hs --> Rtotal2 + h + lpchol_hs
product: 614338
reactant: 614275
product: 614326
reactant: 614263
reactant: 614288
product: 614314
is: ENSECAG00000010997.1
is: http://identifiers.org/ec-code/3.1.1.4
product: 614374
fast: false

614362
type: SpeciesReference
stoichiometry: 1.0
species: 599531

614350
type: SpeciesReference
stoichiometry: 1.0
species: 587803

587803
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: R total 2 position_CO2FULLR2

614301
type: SpeciesReference
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species: 599433

614338
type: SpeciesReference
stoichiometry: 1.0
species: 603602

614275
type: SpeciesReference
stoichiometry: 1.0
species: 599421

614326
type: SpeciesReference
stoichiometry: 1.0
species: 599544

599544
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: H+_H

614263
type: SpeciesReference
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species: 606965

606965
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

614288
type: SpeciesReference
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species: 606977

606977
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

614314
type: SpeciesReference
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species: 603614

603614
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: lysophosphatidylcholine (homo sapiens)_C8H19NO5PFULLRCO2

614374
type: SpeciesReference
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species: 587815

589037
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: O-Acetylcarnitine_C9H17NO4

019502
type: Reaction
reversible: false
is: ENSECAG00000017447.1
product: 716635
fast: false
is: http://identifiers.org/ec-code/2.5.1.22
name: spermine synthase
reactant: 716611
reactant: 716599
product: 716647
notes: R_SPRMS subsystem: Urea cycle/amino group metabolism R_SPRMS equation: [c] : ametam + spmd --> 5mta + h + sprm
product: 716623

716635
type: SpeciesReference
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species: 609690

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type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: Spermine_C10H30N4

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type: SpeciesReference
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species: 590029

590029
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: S-Adenosylmethioninamine_C14H24N6O3S

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species: 609678

716647
type: SpeciesReference
stoichiometry: 1.0
species: 599531

716623
type: SpeciesReference
stoichiometry: 1.0
species: 587092

587092
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5-Methylthioadenosine_C11H15N5O3S

588191
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Acetoacetyl-CoA_C25H36N7O18P3S

588796
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: N-Acetyl-L-glutamate_C7H9NO5

019067
type: Reaction
reactant: 713226
reactant: 713190
reactant: 713165
reactant: 713202
product: 713264
notes: R_SOAT12 subsystem: Cholesterol Metabolism R_SOAT12 equation: [c] : R2coa_hs + chsterol --> coa + xolest_hs R_SOAT12r subsystem: Cholesterol Metabolism R_SOAT12r equation: [r] : R2coa_hs + chsterol --> coa + xolest_hs R_SOAT11r subsystem: Cholesterol Metabolism R_SOAT11r equation: [r] : R1coa_hs + chsterol --> coa + xolest_hs R_SOAT11 subsystem: Cholesterol Metabolism R_SOAT11 equation: [c] : R1coa_hs + chsterol --> coa + xolest_hs
product: 713239
reactant: 713177
product: 713276
reactant: 713214
is: ENSECAG00000007962.1
reversible: false
fast: false
product: 713251

713226
type: SpeciesReference
stoichiometry: 1.0
species: 587755

587755
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: R group 1 Coenzyme A homo sapiens_XCO2C21H31N7O15P3S

713190
type: SpeciesReference
stoichiometry: 1.0
species: 587791

713165
type: SpeciesReference
stoichiometry: 1.0
species: 587767

587767
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: R group 1 Coenzyme A homo sapiens_XCO2C21H31N7O15P3S

713202
type: SpeciesReference
stoichiometry: 2.0
species: 591845

713264
type: SpeciesReference
stoichiometry: 2.0
species: 592402

713239
type: SpeciesReference
stoichiometry: 2.0
species: 612373

612373
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: cholesterol ester_C27H45XCO2

713177
type: SpeciesReference
stoichiometry: 2.0
species: 591905

713276
type: SpeciesReference
stoichiometry: 2.0
species: 612361

612361
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: cholesterol ester_C27H45XCO2

713214
type: SpeciesReference
stoichiometry: 1.0
species: 587779

587779
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: R group 2 Coenzyme A homo sapiens_XCO2C21H31N7O15P3S

713251
type: SpeciesReference
stoichiometry: 2.0
species: 592342

592776
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: chondroitin sulfate A (GalNAc4S-GlcA) and B (IdoA2S-GalNAc4S), precursor 2_C37H54NO37S2X

009367
type: Reaction
is: http://identifiers.org/ec-code/3.1.1.47
reactant: 619697
product: 619733
product: 619721
name: Platelet-activating factor acetylhydrolase
reversible: false
fast: false
notes: R_PAFHe subsystem: Glycerophospholipid Metabolism R_PAFHe equation: [e] : h2o + paf_hs --> ac + ak2lgchol_hs + h
product: 619745
reactant: 619709
is: ENSECAG00000000840.1

619697
type: SpeciesReference
stoichiometry: 1.0
species: 606661

606661
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: _1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens)_C11H23O4NPFULLRCO2

619733
type: SpeciesReference
stoichiometry: 1.0
species: 599544

619721
type: SpeciesReference
stoichiometry: 1.0
species: 588276

588276
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Acetate_C2H3O2

619745
type: SpeciesReference
stoichiometry: 1.0
species: 589664

589664
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: _1-alkyl 2-lysoglycerol 3-phosphocholine_C10H21O5NPFULLR

619709
type: SpeciesReference
stoichiometry: 1.0
species: 599433

588881
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: sialyl (1,3) sialyl (2,6) galactosylgloboside (homo sapiens)_C72H121N4O43FULLRCO

012475
type: Reaction
reactant: 647811
is: ENSECAG00000024950.1
notes: R_SERHL subsystem: Glycine, Serine, and Threonine Metabolism R_SERHL equation: [c] : ser-L --> 2amac + h2o R_THRD_L subsystem: Glycine, Serine, and Threonine Metabolism R_THRD_L equation: [c] : thr-L --> 2obut + nh4
product: 647848
product: 647824
is: http://identifiers.org/ec-code/4.3.1.19
product: 647836
product: 647860
reversible: false
fast: false
reactant: 647799

647811
type: SpeciesReference
stoichiometry: 1.0
species: 610752

647848
type: SpeciesReference
stoichiometry: 1.0
species: 605563

647824
type: SpeciesReference
stoichiometry: 1.0
species: 585065

647836
type: SpeciesReference
stoichiometry: 1.0
species: 585295

647860
type: SpeciesReference
stoichiometry: 1.0
species: 599421

647799
type: SpeciesReference
stoichiometry: 1.0
species: 609352

590186
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: androsterone glucuronide_C25H38O8

010749
type: Reaction
product: 632825
product: 632849
is: ENSECAG00000001014.1
product: 632813
product: 632789
product: 632837
fast: false
notes: R_CHOLATEt3 subsystem: Transport, Extracellular R_CHOLATEt3 equation: atp[c] + cholate[c] + h2o[c] --> adp[c] + cholate[e] + h[c] + pi[c] R_TCHOLAt3 subsystem: Transport, Extracellular R_TCHOLAt3 equation: atp[c] + h2o[c] + tchola[c] --> adp[c] + h[c] + pi[c] + tchola[e] R_ESTRONEGLCt subsystem: Transport, Extracellular R_ESTRONEGLCt equation: atp[c] + estroneglc[c] + h2o[c] --> adp[c] + estroneglc[e] + h[c] + pi[c] R_GCHOLAt3 subsystem: Transport, Extracellular R_GCHOLAt3 equation: atp[c] + gchola[c] + h2o[c] --> adp[c] + gchola[e] + h[c] + pi[c]
reversible: false
reactant: 632705
reactant: 632741
reactant: 632729
product: 632777
reactant: 632765
product: 632801
reactant: 632717
reactant: 632753

632825
type: SpeciesReference
stoichiometry: 4.0
species: 589206

632849
type: SpeciesReference
stoichiometry: 4.0
species: 599531

632813
type: SpeciesReference
stoichiometry: 1.0
species: 597808

632789
type: SpeciesReference
stoichiometry: 4.0
species: 607462

632837
type: SpeciesReference
stoichiometry: 1.0
species: 591712

632705
type: SpeciesReference
stoichiometry: 4.0
species: 590727

632741
type: SpeciesReference
stoichiometry: 1.0
species: 597795

632729
type: SpeciesReference
stoichiometry: 1.0
species: 610115

632777
type: SpeciesReference
stoichiometry: 1.0
species: 610127

632765
type: SpeciesReference
stoichiometry: 4.0
species: 599421

632801
type: SpeciesReference
stoichiometry: 1.0
species: 596101

596101
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: estrone glucuronide_C24H30O8

632717
type: SpeciesReference
stoichiometry: 1.0
species: 596089

596089
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: estrone glucuronide_C24H30O8

632753
type: SpeciesReference
stoichiometry: 1.0
species: 591700

602964
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Lactaldehyde_C3H6O2

010194
type: Reaction
is: http://identifiers.org/ec-code/3.5.1.26
reversible: false
notes: R_GASNASE2ly subsystem: N-Glycan Degradation R_GASNASE2ly equation: [l] : h2o + n2m2nmasn --> Asn-X-Ser/Thr + n2m2nm R_GASNASE3ly subsystem: Keratan sulfate degradation R_GASNASE3ly equation: [l] : h2o + ksi_deg1 --> Asn-X-Ser/Thr + ksi_deg2 R_GASNASEly subsystem: N-Glycan Degradation R_GASNASEly equation: [l] : h2o + s2l2n2m2masn --> Asn-X-Ser/Thr + s2l2n2m2m
product: 627559
product: 627583
reactant: 627499
reactant: 627511
product: 627571
product: 627547
reactant: 627535
fast: false
is: ENSECAG00000000085.1
reactant: 627523

627559
type: SpeciesReference
stoichiometry: 3.0
species: 587526

587526
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: protein-linked asparagine residue (N-glycosylation site)_XH

627583
type: SpeciesReference
stoichiometry: 1.0
species: 609028

609028
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: de-Fuc form of PA6 (w/o peptide linkage)_C84H136N6O62

627499
type: SpeciesReference
stoichiometry: 1.0
species: 605103

605103
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-(N-acetyl-beta-D-glucosaminyl-1,4)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R_C58H96N5O40X

627511
type: SpeciesReference
stoichiometry: 1.0
species: 609052

609052
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: de-Fuc form of PA6_C84H135N6O61X

627571
type: SpeciesReference
stoichiometry: 1.0
species: 601659

601659
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 2_C241H384N17O210S12

627547
type: SpeciesReference
stoichiometry: 1.0
species: 605079

605079
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: n2m2nmasn (w/o peptide linkage)_C58H97N5O41

627535
type: SpeciesReference
stoichiometry: 1.0
species: 601527

601527
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 1_C241H383N17O209S12X

627523
type: SpeciesReference
stoichiometry: 3.0
species: 599457

019477
type: Reaction
fast: false
reactant: 716442
reactant: 716466
is: http://identifiers.org/ec-code/1.14.16.1
product: 716478
product: 716490
notes: R_PHETHPTOX2 subsystem: Tyr, Phe, Trp Biosynthesis R_PHETHPTOX2 equation: [c] : o2 + phe-L + thbpt --> thbpt4acam + tyr-L
reactant: 716454
reversible: false
name: L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)
is: ENSECAG00000019047.1

716442
type: SpeciesReference
stoichiometry: 1.0
species: 610499

610499
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Tetrahydrobiopterin_C9H15N5O3

716466
type: SpeciesReference
stoichiometry: 1.0
species: 605960

716478
type: SpeciesReference
stoichiometry: 1.0
species: 610487

716490
type: SpeciesReference
stoichiometry: 1.0
species: 611333

716454
type: SpeciesReference
stoichiometry: 1.0
species: 607292

015907
type: Reaction
product: 682325
notes: R_HBZOPT10m subsystem: Ubiquinone Biosynthesis R_HBZOPT10m equation: [m] : 4hbz + decdp --> 3dphb + ppi
reactant: 682301
reactant: 682313
name: Hydroxybenzoate Decaprenyltransferase
fast: false
product: 682337
reversible: false
is: ENSECAG00000012542.1

682325
type: SpeciesReference
stoichiometry: 1.0
species: 585597

585597
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _3-Decaprenyl-4-hydroxybenzoate_C57H85O3

682301
type: SpeciesReference
stoichiometry: 1.0
species: 594178

594178
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: all trans Decaprenyl diphosphate_C50H81O7P2

682313
type: SpeciesReference
stoichiometry: 1.0
species: 586375

586375
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _4-Hydroxybenzoate_C7H5O3

682337
type: SpeciesReference
stoichiometry: 1.0
species: 607740

607740
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Diphosphate_HO7P2

586252
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _4-Acetamidobutanoate_C6H10NO3

597662
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: galactocerebroside (homo sapiens)_C24H46NO7FULLRCO

013815
type: Reaction
reactant: 661233
is: ENSECAG00000024948.1
product: 661257
notes: R_PROSTGD2t subsystem: Transport, Extracellular R_PROSTGD2t equation: hco3[c] + prostgd2[e] <==> hco3[e] + prostgd2[c] R_PROSTGE2t subsystem: Transport, Extracellular R_PROSTGE2t equation: hco3[c] + prostge2[e] <==> hco3[e] + prostge2[c] R_PROSTGE1t subsystem: Transport, Extracellular R_PROSTGE1t equation: hco3[c] + prostge1[e] <==> hco3[e] + prostge1[c]
product: 661269
product: 661245
fast: false
reactant: 661209
product: 661281
reactant: 661197
reactant: 661221
reversible: true

661233
type: SpeciesReference
stoichiometry: 1.0
species: 608283

661257
type: SpeciesReference
stoichiometry: 1.0
species: 608247

661269
type: SpeciesReference
stoichiometry: 1.0
species: 608211

608211
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Prostaglandin D2_C20H31O5

661245
type: SpeciesReference
stoichiometry: 1.0
species: 608271

661209
type: SpeciesReference
stoichiometry: 1.0
species: 608223

608223
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Prostaglandin D2_C20H31O5

661281
type: SpeciesReference
stoichiometry: 3.0
species: 599701

661197
type: SpeciesReference
stoichiometry: 3.0
species: 599689

661221
type: SpeciesReference
stoichiometry: 1.0
species: 608259

608259
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Prostaglandin E1_C20H33O5

594733
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: dIDP_C10H11N4O10P2

607861
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Protoporphyrinogen IX_C34H38N4O4

597192
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: alpha-D-Glucosyl-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1785H2940N20O670P20

587429
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: heptaglutamyl folate (DHF)_C49H55N13O24

014767
type: Reaction
is: ENSECAG00000012339.1
product: 669533
is: ENSECAG00000014984.1
reactant: 669521
reversible: true
is: ENSECAG00000023165.1
name: phosphoglycerate kinase
product: 669545
is: http://identifiers.org/ec-code/2.7.2.3
reactant: 669509
fast: false
notes: R_PGK subsystem: Glycolysis/Gluconeogenesis R_PGK equation: [c] : 3pg + atp <==> 13dpg + adp

669533
type: SpeciesReference
stoichiometry: 1.0
species: 589206

669521
type: SpeciesReference
stoichiometry: 1.0
species: 586058

586058
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Phospho-D-glycerate_C3H4O7P

669545
type: SpeciesReference
stoichiometry: 1.0
species: 584786

584786
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Phospho-D-glyceroyl phosphate_C3H4O10P2

669509
type: SpeciesReference
stoichiometry: 1.0
species: 590727

610632
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: _5,6,7,8-Tetrahydrofolate_C19H21N7O6

589242
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: ADP_C10H12N5O10P2

013091
type: Reaction
is: ENSECAG00000020213.1
product: 652969
fast: false
product: 652993
reversible: false
name: phosphatidyl-CMP: glycerophosphate phosphatidyltransferase
is: http://identifiers.org/ec-code/2.7.8.11
product: 652981
reactant: 652957
notes: R_PGPPT subsystem: Glycerophospholipid Metabolism R_PGPPT equation: [c] : cdpdag_hs + glyc3p --> cmp + h + pgp_hs
reactant: 652945

652969
type: SpeciesReference
stoichiometry: 1.0
species: 607280

652993
type: SpeciesReference
stoichiometry: 1.0
species: 599531

652981
type: SpeciesReference
stoichiometry: 1.0
species: 592147

652957
type: SpeciesReference
stoichiometry: 1.0
species: 591531

591531
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: CDP diacylglycerol (homo sapiens)_C12H17N3O11P2FULLRCO2FULLR2CO2

652945
type: SpeciesReference
stoichiometry: 1.0
species: 598542

598542
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Glycerol 3-phosphate_C3H7O6P

611513
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353

587514
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: acyl carrier protein_C11H21N2O7PRS

584677
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _12-Hydroperoxyeicosa-5,8,10,14-tetraenoate_C20H31O4

017361
type: Reaction
is: http://identifiers.org/ec-code/5.3.3.12
product: 695192
is: ENSECAG00000000521.1
reactant: 695180
is: ENSECAG00000012326.1
is: ENSECAG00000006966.1
is: ENSECAG00000015055.1
name: Dopachrome tautomerase
fast: false
is: ENSECAG00000011660.1
is: ENSECAG00000007754.1
reversible: true
is: ENSECAG00000005190.1
notes: R_DCT subsystem: Tyrosine metabolism R_DCT equation: [c] : L-dpchrm <==> 56dihindlcrbxlt
is: ENSECAG00000022510.1
is: ENSECAG00000008864.1
is: ENSECAG00000016614.1

695192
type: SpeciesReference
stoichiometry: 1.0
species: 586664

586664
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5,6-Dihydroxyindole-2-carboxylate_C9H6NO4

695180
type: SpeciesReference
stoichiometry: 1.0
species: 587586

587586
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Dopachrome_C9H6NO4

594952
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _2,6 dimethylheptanoyl-CoA_C30H52N7O17P3S

591333
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: cAMP_C10H11N5O6P

014020
type: Reaction
reversible: false
is: http://identifiers.org/ec-code/1.13.11.42
product: 662557
product: 662569
reactant: 662509
fast: false
product: 662545
notes: R_SRTN23OX subsystem: Tryptophan metabolism R_SRTN23OX equation: [c] : o2 + srtn --> f5hoxkyn R_MELATN23DOX subsystem: Tryptophan metabolism R_MELATN23DOX equation: [c] : melatn + o2 --> fna5moxam R_5HTRPDOX subsystem: Tryptophan metabolism R_5HTRPDOX equation: [c] : 5htrp + o2 --> 5hoxnfkyn
reactant: 662521
is: ENSECAG00000006663.1
reactant: 662533
reactant: 662497

662557
type: SpeciesReference
stoichiometry: 1.0
species: 587008

587008
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5-Hydroxy-N-formylkynurenine_C11H12N2O5

662569
type: SpeciesReference
stoichiometry: 1.0
species: 596564

596564
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Formyl-N-acetyl-5-methoxykynurenamine_C13H16N2O4

662509
type: SpeciesReference
stoichiometry: 1.0
species: 609715

662545
type: SpeciesReference
stoichiometry: 1.0
species: 596288

596288
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Formyl-5-hydroxykynurenamine_C10H13N2O3

662521
type: SpeciesReference
stoichiometry: 1.0
species: 587020

662533
type: SpeciesReference
stoichiometry: 3.0
species: 605960

662497
type: SpeciesReference
stoichiometry: 1.0
species: 604403

604403
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Melatonin_C13H16N2O2

016111
type: Reaction
name: galactokinase
notes: R_GALK subsystem: Galactose metabolism R_GALK equation: [c] : atp + gal --> adp + gal1p + h
is: ENSECAG00000019803.1
is: ENSECAG00000017631.1
product: 684247
product: 684235
reactant: 684211
reactant: 684223
is: http://identifiers.org/ec-code/2.7.1.6
reversible: false
product: 684259
fast: false

684247
type: SpeciesReference
stoichiometry: 1.0
species: 589206

684235
type: SpeciesReference
stoichiometry: 1.0
species: 597396

597396
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: alpha-D-Galactose 1-phosphate_C6H11O9P

684211
type: SpeciesReference
stoichiometry: 1.0
species: 590727

684223
type: SpeciesReference
stoichiometry: 1.0
species: 597408

597408
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Galactose_C6H12O6

684259
type: SpeciesReference
stoichiometry: 1.0
species: 599531

595413
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: dTDP_C10H13N2O11P2

584906
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _1-Methylnicotinamide_C7H9N2O

591809
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Choline phosphate_C5H13NO4P

017877
type: Reaction
reversible: true
is: ENSECAG00000022433.1
fast: false
reactant: 700106
reactant: 700094
name: ATP Creatine kinase (c)
product: 700118
is: ENSECAG00000009054.1
notes: R_CKc subsystem: Urea cycle/amino group metabolism R_CKc equation: [c] : atp + creat <==> adp + pcreat
product: 700130
is: http://identifiers.org/ec-code/2.7.3.2

700106
type: SpeciesReference
stoichiometry: 1.0
species: 592535

700094
type: SpeciesReference
stoichiometry: 1.0
species: 590727

700118
type: SpeciesReference
stoichiometry: 1.0
species: 589206

700130
type: SpeciesReference
stoichiometry: 1.0
species: 607050

015271
type: Reaction
reversible: true
reactant: 673957
product: 673981
reactant: 673969
notes: R_GLUt2m subsystem: Transport, Mitochondrial R_GLUt2m equation: glu-L[c] + h[c] <==> glu-L[m] + h[m]
is: ENSECAG00000011808.1
fast: false
product: 673993
name: L-glutamate reversible transport via proton symport, mitochondrial
is: ENSECAG00000008033.1

673957
type: SpeciesReference
stoichiometry: 1.0
species: 598265

673981
type: SpeciesReference
stoichiometry: 1.0
species: 598301

673969
type: SpeciesReference
stoichiometry: 1.0
species: 599531

673993
type: SpeciesReference
stoichiometry: 1.0
species: 599581

585719
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _3-Hydroxy-2-methylpropanoate_C4H7O3

013562
type: Reaction
name: Ethanolamine kinase
fast: false
is: ENSECAG00000016809.1
product: 659308
is: ENSECAG00000007231.1
product: 659320
reactant: 659272
product: 659296
reversible: false
notes: R_ETHAK subsystem: Glycerophospholipid Metabolism R_ETHAK equation: [c] : atp + etha --> adp + ethamp + h
is: http://identifiers.org/ec-code/2.7.1.82
reactant: 659284

659308
type: SpeciesReference
stoichiometry: 1.0
species: 589206

659320
type: SpeciesReference
stoichiometry: 1.0
species: 599531

659272
type: SpeciesReference
stoichiometry: 1.0
species: 596187

659296
type: SpeciesReference
stoichiometry: 1.0
species: 596200

659284
type: SpeciesReference
stoichiometry: 1.0
species: 590727

593148
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 3_C37H53NO40S3X

012161
type: Reaction
is: http://identifiers.org/ec-code/2.1.1.8
is: ENSECAG00000011592.1
fast: false
notes: R_SAMHISTA subsystem: Histidine Metabolism R_SAMHISTA equation: [c] : amet + hista --> ahcys + h + mhista
product: 644231
reactant: 644219
product: 644255
product: 644243
name: S-Adenosyl-L-methionine:histamine N-tele-methyltransferase
reactant: 644207
reversible: false

644231
type: SpeciesReference
stoichiometry: 1.0
species: 589555

644219
type: SpeciesReference
stoichiometry: 1.0
species: 600049

600049
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Histamine_C5H10N3

644255
type: SpeciesReference
stoichiometry: 1.0
species: 599531

644243
type: SpeciesReference
stoichiometry: 1.0
species: 604645

604645
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-Methylhistamine_C6H12N3

644207
type: SpeciesReference
stoichiometry: 1.0
species: 589981

589981
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: S-Adenosyl-L-methionine_C15H23N6O5S

013370
type: Reaction
product: 656558
reversible: false
product: 656546
notes: R_PPCOAOm subsystem: Propanoate Metabolism R_PPCOAOm equation: [m] : fad + ppcoa --> fadh2 + prpncoa R_ACOAD1fm subsystem: Butanoate Metabolism R_ACOAD1fm equation: [m] : btcoa + fad --> b2coa + fadh2 R_ACOAD9m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ACOAD9m equation: [m] : fad + ibcoa --> 2mp2coa + fadh2
product: 656582
reactant: 656509
reactant: 656534
is: ENSECAG00000011007.1
fast: false
reactant: 656522
is: http://identifiers.org/ec-code/1.3.99.12
is: http://identifiers.org/ec-code/1.3.99.3
product: 656570
is: http://identifiers.org/ec-code/1.3.99.2
reactant: 656497

656558
type: SpeciesReference
stoichiometry: 1.0
species: 608367

608367
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Propenoyl-CoA_C24H34N7O17P3S

656546
type: SpeciesReference
stoichiometry: 3.0
species: 596372

656582
type: SpeciesReference
stoichiometry: 1.0
species: 585283

585283
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401

656509
type: SpeciesReference
stoichiometry: 1.0
species: 607703

656534
type: SpeciesReference
stoichiometry: 3.0
species: 596324

656522
type: SpeciesReference
stoichiometry: 1.0
species: 600888

656570
type: SpeciesReference
stoichiometry: 1.0
species: 590799

590799
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Crotonoyl-CoA_C25H36N7O17P3S

656497
type: SpeciesReference
stoichiometry: 1.0
species: 591088

591088
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Butanoyl-CoA_C25H38N7O17P3S

011027
type: Reaction
reactant: 635285
is: ENSECAG00000009215.1
product: 635310
fast: false
product: 635297
name: Methionine/Leucine exchange (Met in)
reactant: 635272
notes: R_METLEUex subsystem: Transport, Extracellular R_METLEUex equation: leu-L[c] + met-L[e] --> leu-L[e] + met-L[c]
reversible: false

635285
type: SpeciesReference
stoichiometry: 1.0
species: 603048

635310
type: SpeciesReference
stoichiometry: 1.0
species: 604560

635297
type: SpeciesReference
stoichiometry: 1.0
species: 603060

635272
type: SpeciesReference
stoichiometry: 1.0
species: 604572

011232
type: Reaction
notes: R_AGMTm subsystem: Arginine and Proline Metabolism R_AGMTm equation: [m] : agm + h2o --> ptrc + urea
is: ENSECAG00000008308.1
name: agmatinase (m)
product: 636815
reversible: false
product: 636827
fast: false
reactant: 636803
reactant: 636790
is: http://identifiers.org/ec-code/3.5.3.11

636815
type: SpeciesReference
stoichiometry: 1.0
species: 608531

608531
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Putrescine_C4H14N2

636827
type: SpeciesReference
stoichiometry: 1.0
species: 611829

611829
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Urea_CH4N2O

636803
type: SpeciesReference
stoichiometry: 1.0
species: 589495

589495
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Agmatine_C5H16N4

636790
type: SpeciesReference
stoichiometry: 1.0
species: 599469

015787
type: Reaction
product: 680720
fast: false
reactant: 680648
notes: R_P45011B11m subsystem: Steroid Metabolism R_P45011B11m equation: [m] : 11docrtstrn + h + nadph + o2 --> crtstrn + h2o + nadp R_P45011B12m subsystem: Steroid Metabolism R_P45011B12m equation: [m] : 11docrtsl + h + nadph + o2 --> crtsl + h2o + nadp
is: http://identifiers.org/ec-code/1.14.15.4
product: 680684
reactant: 680636
is: ENSECAG00000000832.1
is: ENSECAG00000008530.1
product: 680696
reactant: 680672
reactant: 680660
reversible: false
product: 680708
reactant: 680624

680720
type: SpeciesReference
stoichiometry: 2.0
species: 605394

680648
type: SpeciesReference
stoichiometry: 2.0
species: 605454

680684
type: SpeciesReference
stoichiometry: 1.0
species: 592692

592692
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Cortisol_C21H30O5

680636
type: SpeciesReference
stoichiometry: 1.0
species: 584629

680696
type: SpeciesReference
stoichiometry: 2.0
species: 599469

680672
type: SpeciesReference
stoichiometry: 2.0
species: 599581

680660
type: SpeciesReference
stoichiometry: 2.0
species: 605984

680708
type: SpeciesReference
stoichiometry: 1.0
species: 592716

592716
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Corticosterone_C21H30O4

680624
type: SpeciesReference
stoichiometry: 1.0
species: 584653

009391
type: Reaction
notes: R_M4BET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4BET2er equation: [r] : mem2emgacpail_hs + pe_hs --> dag_hs + m(em)3gacpail_hs R_H6ET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6ET3er equation: [r] : m2emgacpail_hs + pe_hs --> dag_hs + em2emgacpail_hs R_H6_APOS_ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6_APOS_ET2er equation: [r] : em3gacpail_hs + pe_hs --> dag_hs + emem2gacpail_hs R_H7ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7ET2er equation: [r] : em2emgacpail_hs + pe_hs --> dag_hs + gpi_hs R_H4ET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H4ET3er equation: [r] : m3gacpail_hs + pe_hs --> dag_hs + em3gacpail_hs R_M4CET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4CET3er equation: [r] : m3emgacpail_hs + pe_hs --> dag_hs + mem2emgacpail_hs
product: 619901
product: 619889
reactant: 619805
product: 619949
product: 619925
is: ENSECAG00000012487.1
reactant: 619817
reactant: 619865
reversible: false
reactant: 619877
reactant: 619829
reactant: 619841
product: 619937
product: 619913
fast: false
product: 619961
reactant: 619853

619901
type: SpeciesReference
stoichiometry: 1.0
species: 598928

598928
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: glycophosphatidylinositol (GPI) anchor precursor (3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol) (H8)_C55H106N4O38P4FULLRCO2FULLR2CO2

619889
type: SpeciesReference
stoichiometry: 1.0
species: 595920

619805
type: SpeciesReference
stoichiometry: 1.0
species: 595920

619949
type: SpeciesReference
stoichiometry: 1.0
species: 604101

604101
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: mannosyl-3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol (M4A)_C61H116N4O43P4FULLRCO2FULLR2CO2

619925
type: SpeciesReference
stoichiometry: 1.0
species: 604415

604415
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: ({[(mannosyl),(phosphoethanolaminyl)]-dimannosyl},{phosphoethanolaminyl})-mannosyl-glucosaminyl-acylphosphatidylinositol (M4B)_C59H110N3O40P3FULLRCO2FULLR2CO2

619817
type: SpeciesReference
stoichiometry: 6.0
species: 607147

619865
type: SpeciesReference
stoichiometry: 1.0
species: 603782

603782
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: (trimannosyl),(phosphoethanolaminyl)-mannosyl-glucosaminyl-acylphosphatidylinositol (M4C)_C57H104N2O37P2FULLRCO2FULLR2CO2

619877
type: SpeciesReference
stoichiometry: 1.0
species: 595896

595896
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: (phosphoethanolaminyl-dimannosyl),(phosphoethanolaminyl)-mannosyl-glucosaminyl-acylphosphatidylinositol (H7)_C53H100N3O35P3FULLRCO2FULLR2CO2

619829
type: SpeciesReference
stoichiometry: 1.0
species: 603734

619841
type: SpeciesReference
stoichiometry: 1.0
species: 603794

619937
type: SpeciesReference
stoichiometry: 1.0
species: 595932

619913
type: SpeciesReference
stoichiometry: 6.0
species: 593730

593730
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2

619961
type: SpeciesReference
stoichiometry: 1.0
species: 595896

619853
type: SpeciesReference
stoichiometry: 1.0
species: 604415

018046
type: Reaction
is: ENSECAG00000022431.1
product: 701941
is: ENSECAG00000022051.1
product: 701954
fast: false
is: ENSECAG00000003944.1
notes: R_GAPD subsystem: Glycolysis/Gluconeogenesis R_GAPD equation: [c] : g3p + nad + pi <==> 13dpg + h + nadh
reactant: 701915
is: http://identifiers.org/ec-code/1.2.1.12
reactant: 701889
name: glyceraldehyde-3-phosphate dehydrogenase
reversible: true
is: ENSECAG00000003757.1
product: 701928
reactant: 701902

701941
type: SpeciesReference
stoichiometry: 1.0
species: 599531

701954
type: SpeciesReference
stoichiometry: 1.0
species: 605322

701915
type: SpeciesReference
stoichiometry: 1.0
species: 597288

701889
type: SpeciesReference
stoichiometry: 1.0
species: 607462

701928
type: SpeciesReference
stoichiometry: 1.0
species: 584786

701902
type: SpeciesReference
stoichiometry: 1.0
species: 605248

599857
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341

596853
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Fucose_C6H12O5

604946
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: (S)-Methylmalonyl-CoA_C25H35N7O19P3S

016319
type: Reaction
product: 686795
reactant: 686782
notes: R_TPI subsystem: Glycolysis/Gluconeogenesis R_TPI equation: [c] : dhap <==> g3p
is: ENSECAG00000015581.1
is: http://identifiers.org/ec-code/5.3.1.1
fast: false
reversible: true
name: triose-phosphate isomerase

686795
type: SpeciesReference
stoichiometry: 1.0
species: 597288

686782
type: SpeciesReference
stoichiometry: 1.0
species: 594396

016524
type: Reaction
product: 688261
reactant: 688201
reactant: 688153
product: 688286
product: 688237
reactant: 688165
product: 688213
product: 688273
is: ENSECAG00000008398.1
reversible: false
product: 688249
reactant: 688141
notes: R_DPROOp subsystem: Arginine and Proline Metabolism R_DPROOp equation: [x] : o2 + pro-D --> 1p2cbxl + h + h2o2 R_DALAOXx subsystem: D-alanine metabolism R_DALAOXx equation: [x] : ala-D + h2o + o2 --> h2o2 + nh4 + pyr R_DARGOp subsystem: D-arg and D-orn metabolism R_DARGOp equation: [x] : arg-D + h2o + o2 --> 5g2oxpt + h2o2 + nh4 R_DORNOp subsystem: D-arg and D-orn metabolism R_DORNOp equation: [x] : h2o + o2 + orn-D --> 5a2opntn + h2o2 + nh4
reactant: 688177
product: 688225
reactant: 688189
is: http://identifiers.org/ec-code/1.4.3.3
fast: false

688261
type: SpeciesReference
stoichiometry: 1.0
species: 599617

688201
type: SpeciesReference
stoichiometry: 1.0
species: 608126

608126
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: D-Proline_C5H9NO2

688153
type: SpeciesReference
stoichiometry: 4.0
species: 606021

688286
type: SpeciesReference
stoichiometry: 1.0
species: 608677

608677
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Pyruvate_C3H3O3

688237
type: SpeciesReference
stoichiometry: 4.0
species: 599409

688165
type: SpeciesReference
stoichiometry: 1.0
species: 606455

688213
type: SpeciesReference
stoichiometry: 1.0
species: 586712

688273
type: SpeciesReference
stoichiometry: 3.0
species: 605623

605623
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Ammonium_H4N

688249
type: SpeciesReference
stoichiometry: 1.0
species: 584931

584931
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: _1-Pyrroline-2-carboxylate_C5H6NO2

688141
type: SpeciesReference
stoichiometry: 3.0
species: 599506

688177
type: SpeciesReference
stoichiometry: 1.0
species: 589822

589822
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: D-Alanine_C3H7NO2

688225
type: SpeciesReference
stoichiometry: 1.0
species: 586936

586936
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: _5-Guanidino-2-oxopentanoate_C6H11N3O3

688189
type: SpeciesReference
stoichiometry: 1.0
species: 590535

590535
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: D-Arginine_C6H15N4O2

012803
type: Reaction
product: 650891
product: 650879
is: ENSECAG00000002868.1
is: http://identifiers.org/ec-code/1.1.1.62
is: ENSECAG00000023091.1
fast: false
reactant: 650855
reactant: 650867
reactant: 650843
name: testicular 17-beta-hydroxysteroid dehydrogenase
reversible: false
notes: R_HSD17B3r subsystem: Steroid Metabolism R_HSD17B3r equation: [r] : andrstndn + h + nadph --> nadp + tststerone

650891
type: SpeciesReference
stoichiometry: 1.0
species: 605418

650879
type: SpeciesReference
stoichiometry: 1.0
species: 611138

611138
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Testosterone_C19H28O2

650855
type: SpeciesReference
stoichiometry: 1.0
species: 590138

650867
type: SpeciesReference
stoichiometry: 1.0
species: 599605

650843
type: SpeciesReference
stoichiometry: 1.0
species: 605479

587707
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: Protein N6,N6-dimethyl-L-lysine_C2H7X

596987
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)2 (Cer)1_C84H145N4O50FULLRCO

013658
type: Reaction
is: ENSECAG00000014559.1
product: 660010
reactant: 659998
fast: false
notes: R_THMTP subsystem: Thiamine Metabolism R_THMTP equation: [c] : h2o + thmtp --> h + pi + thmpp
reactant: 659986
product: 660022
name: thiamine-triphosphatase
is: http://identifiers.org/ec-code/3.6.1.28
reversible: false
product: 660034

660010
type: SpeciesReference
stoichiometry: 1.0
species: 607462

659998
type: SpeciesReference
stoichiometry: 1.0
species: 599421

659986
type: SpeciesReference
stoichiometry: 1.0
species: 610716

660022
type: SpeciesReference
stoichiometry: 1.0
species: 610704

610704
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Thiamine diphosphate_C12H16N4O7P2S

660034
type: SpeciesReference
stoichiometry: 1.0
species: 599531

011306
type: Reaction
is: ENSECAG00000023417.1
is: http://identifiers.org/ec-code/4.99.1.1
notes: R_FCLTm subsystem: Heme Biosynthesis R_FCLTm equation: [m] : fe2 + ppp9 --> (2) h + pheme
reactant: 637261
name: Ferrochelatase, mitochondrial
reactant: 637273
fast: false
product: 637285
product: 637297
reversible: false

637261
type: SpeciesReference
stoichiometry: 1.0
species: 607837

607837
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Protoporphyrin_C34H32N4O4

637273
type: SpeciesReference
stoichiometry: 1.0
species: 596492

596492
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Fe2+_Fe

637285
type: SpeciesReference
stoichiometry: 1.0
species: 607352

607352
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Protoheme_C34H30FeN4O4

637297
type: SpeciesReference
stoichiometry: 2.0
species: 599581

593803
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Decanoyl-CoA (n-C10:0CoA)_C31H50N7O17P3S

012257
type: Reaction
reactant: 645122
reactant: 645135
reactant: 645110
notes: R_CHAT subsystem: Glycerophospholipid Metabolism R_CHAT equation: [c] : accoa + chol <==> ach + coa R_CHATn subsystem: Glycerophospholipid Metabolism R_CHATn equation: [n] : accoa + chol <==> ach + coa
product: 645183
product: 645195
product: 645159
fast: false
product: 645171
reversible: true
is: ENSECAG00000021611.1
reactant: 645147

645122
type: SpeciesReference
stoichiometry: 1.0
species: 588444

588444
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: Acetyl-CoA_C23H34N7O17P3S

645135
type: SpeciesReference
stoichiometry: 1.0
species: 591628

645110
type: SpeciesReference
stoichiometry: 1.0
species: 591676

591676
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: Choline_C5H14NO

645183
type: SpeciesReference
stoichiometry: 1.0
species: 588845

588845
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: Acetylcholine_C7H16NO2

645195
type: SpeciesReference
stoichiometry: 1.0
species: 588820

645159
type: SpeciesReference
stoichiometry: 1.0
species: 592390

592390
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: Coenzyme A_C21H32N7O16P3S

645171
type: SpeciesReference
stoichiometry: 1.0
species: 592342

645147
type: SpeciesReference
stoichiometry: 1.0
species: 588408

010012
type: Reaction
product: 625766
product: 625779
reactant: 625741
is: ENSECAG00000013331.1
product: 625791
fast: false
reversible: false
reactant: 625716
notes: R_ACGAMK subsystem: Aminosugar Metabolism R_ACGAMK equation: [c] : acgam + atp --> acgam6p + adp + h R_AMANK subsystem: Aminosugar Metabolism R_AMANK equation: [c] : acmana + atp --> acmanap + adp + h
is: http://identifiers.org/ec-code/2.7.1.60
is: http://identifiers.org/ec-code/2.7.1.59
product: 625753
reactant: 625728

625766
type: SpeciesReference
stoichiometry: 1.0
species: 588675

588675
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-Acetyl-D-glucosamine 6-phosphate_C8H14NO9P

625779
type: SpeciesReference
stoichiometry: 2.0
species: 589206

625741
type: SpeciesReference
stoichiometry: 1.0
species: 588857

625791
type: SpeciesReference
stoichiometry: 2.0
species: 599531

625716
type: SpeciesReference
stoichiometry: 1.0
species: 588687

588687
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-Acetyl-D-glucosamine_C8H15NO6

625753
type: SpeciesReference
stoichiometry: 1.0
species: 588869

625728
type: SpeciesReference
stoichiometry: 2.0
species: 590727

597638
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: galactosyl glucosyl ceramide_C30H56NO12FULLRCO

593524
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Cysteine_C3H7NO2S

018455
type: Reaction
reversible: true
product: 705694
is: http://identifiers.org/ec-code/2.6.1.42
product: 705682
reactant: 705622
reactant: 705634
is: ENSECAG00000011310.1
is: http://identifiers.org/ec-code/2.6.1.6
fast: false
reactant: 705610
product: 705670
reactant: 705646
product: 705658
notes: R_VALTAm subsystem: Valine, Leucine, and Isoleucine Metabolism R_VALTAm equation: [m] : akg + val-L <==> 3mob + glu-L R_ILETAm subsystem: Valine, Leucine, and Isoleucine Metabolism R_ILETAm equation: [m] : akg + ile-L <==> 3mop + glu-L R_LEUTAm subsystem: Valine, Leucine, and Isoleucine Metabolism R_LEUTAm equation: [m] : akg + leu-L <==> 4mop + glu-L

705694
type: SpeciesReference
stoichiometry: 1.0
species: 585926

705682
type: SpeciesReference
stoichiometry: 3.0
species: 598301

705622
type: SpeciesReference
stoichiometry: 1.0
species: 603072

603072
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Leucine_C6H13NO2

705634
type: SpeciesReference
stoichiometry: 1.0
species: 612034

612034
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Valine_C5H11NO2

705610
type: SpeciesReference
stoichiometry: 3.0
species: 589712

705670
type: SpeciesReference
stoichiometry: 1.0
species: 585902

705646
type: SpeciesReference
stoichiometry: 1.0
species: 601056

601056
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Isoleucine_C6H13NO2

705658
type: SpeciesReference
stoichiometry: 1.0
species: 586496

010544
type: Reaction
product: 631088
reactant: 631076
notes: R_ACGAMPM subsystem: Aminosugar Metabolism R_ACGAMPM equation: [c] : acgam6p <==> acgam1p
is: ENSECAG00000023967.1
is: http://identifiers.org/ec-code/5.4.2.3
fast: false
reversible: true
name: phosphoacetylglucosamine mutase

631088
type: SpeciesReference
stoichiometry: 1.0
species: 588663

588663
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-Acetyl-D-glucosamine 1-phosphate_C8H14NO9P

631076
type: SpeciesReference
stoichiometry: 1.0
species: 588675

011099
type: Reaction
name: protein lysine peptidase (endoplasmic reticulum)
is: ENSECAG00000007179.1
product: 635889
reversible: false
is: ENSECAG00000023559.1
fast: false
is: ENSECAG00000021187.1
reactant: 635865
is: ENSECAG00000006491.1
is: ENSECAG00000016480.1
notes: R_PLYSPSer subsystem: Lysine Metabolism R_PLYSPSer equation: [r] : Ntmelys + h2o --> pepslys + tmlys
product: 635901
is: ENSECAG00000017024.1
reactant: 635877

635889
type: SpeciesReference
stoichiometry: 1.0
species: 607208

607208
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: peptide sans lysine_X

635865
type: SpeciesReference
stoichiometry: 1.0
species: 587743

587743
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Protein N6,N6,N6-trimethyl-L-lysine_C3H10X

635901
type: SpeciesReference
stoichiometry: 1.0
species: 610884

635877
type: SpeciesReference
stoichiometry: 1.0
species: 599493

588615
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Type IIIA glycolipid_C78H135N4O45FULLRCO

587200
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: haxglutamyl folate (DHF)_C44H49N12O21

610572
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate_C27H45O5

019272
type: Reaction
reversible: false
product: 714609
reactant: 714597
is: ENSECAG00000011701.1
is: http://identifiers.org/ec-code/3.5.1.23
name: N-acylsphingosine amidohydrolase
notes: R_ASAH1 subsystem: Sphingolipid Metabolism R_ASAH1 equation: [l] : crm_hs + h2o --> Rtotal + sphings
reactant: 714585
is: ENSECAG00000007080.1
product: 714621
fast: false

714609
type: SpeciesReference
stoichiometry: 1.0
species: 609593

609593
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Sphingosine_C18H38NO2

714597
type: SpeciesReference
stoichiometry: 1.0
species: 599457

714585
type: SpeciesReference
stoichiometry: 1.0
species: 592595

714621
type: SpeciesReference
stoichiometry: 1.0
species: 587973

587973
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: R total_CO2FULLR

013802
type: Reaction
reactant: 661148
is: http://identifiers.org/ec-code/4.2.1.17
is: ENSECAG00000024945.1
product: 661172
notes: R_ECOAH1x subsystem: Tryptophan metabolism R_ECOAH1x equation: [x] : 3hbcoa <==> b2coa + h2o R_C2M26DCOAHLx subsystem: Limonene and pinene degradation R_C2M26DCOAHLx equation: [x] : c2m26dcoa + h2o <==> 3h26dm5coa R_T2M26DCOAHLx subsystem: Limonene and pinene degradation R_T2M26DCOAHLx equation: [x] : h2o + t2m26dcoa <==> 3h26dm5coa
product: 661184
reversible: true
reactant: 661124
reactant: 661136
reactant: 661112
fast: false
product: 661160

661148
type: SpeciesReference
stoichiometry: 1.0
species: 610007

610007
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425

661172
type: SpeciesReference
stoichiometry: 1.0
species: 590811

661184
type: SpeciesReference
stoichiometry: 2.0
species: 585634

661124
type: SpeciesReference
stoichiometry: 1.0
species: 591271

591271
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425

661136
type: SpeciesReference
stoichiometry: 1.0
species: 585682

585682
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425

661112
type: SpeciesReference
stoichiometry: 2.0
species: 599506

661160
type: SpeciesReference
stoichiometry: 1.0
species: 599506

596017
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: estriol_C18H24O3

608331
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Prostaglandin H2_C20H31O5

597252
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: (alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C88H147N2O70X

600996
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: IDP_C10H11N4O11P2

591004
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Biliverdin_C33H32N4O6

592184
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: CMP_C9H12N3O8P

009939
type: Reaction
reversible: false
notes: R_NOS2 subsystem: Arginine and Proline Metabolism R_NOS2 equation: [c] : nadph + (2) nwharg + (2) o2 --> (2) citr-L + h + (2) h2o + nadp + (2) no R_NOS1 subsystem: Arginine and Proline Metabolism R_NOS1 equation: [c] : arg-L + h + nadph + o2 --> h2o + nadp + nwharg
is: http://identifiers.org/ec-code/1.14.13.39
product: 625247
reactant: 625171
reactant: 625145
product: 625235
is: ENSECAG00000009126.1
reactant: 625121
product: 625197
is: ENSECAG00000024562.1
product: 625184
reactant: 625133
reactant: 625158
product: 625223
fast: false
product: 625210
is: ENSECAG00000024761.1

625247
type: SpeciesReference
stoichiometry: 1.0
species: 599531

625171
type: SpeciesReference
stoichiometry: 2.0
species: 605442

625145
type: SpeciesReference
stoichiometry: 3.0
species: 605960

625235
type: SpeciesReference
stoichiometry: 3.0
species: 599421

625121
type: SpeciesReference
stoichiometry: 2.0
species: 605948

605948
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-(omega)-Hydroxyarginine_C6H15N4O3

625197
type: SpeciesReference
stoichiometry: 2.0
species: 592002

592002
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Citrulline_C6H13N3O3

625184
type: SpeciesReference
stoichiometry: 1.0
species: 605948

625133
type: SpeciesReference
stoichiometry: 1.0
species: 590547

625158
type: SpeciesReference
stoichiometry: 1.0
species: 599531

625223
type: SpeciesReference
stoichiometry: 2.0
species: 605780

605780
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Nitric oxide_NO

625210
type: SpeciesReference
stoichiometry: 2.0
species: 605370

017697
type: Reaction
product: 698914
is: http://identifiers.org/ec-code/1.14.14.1
product: 698902
product: 698878
reactant: 698830
reactant: 698842
reactant: 698866
notes: R_LNS14DMr subsystem: Cholesterol Metabolism R_LNS14DMr equation: [r] : (2) h + lanost + (3) nadph + (3) o2 --> 44mctr + for + (4) h2o + (3) nadp
name: cytochrome P450 lanosterol 14-alpha-demethylase
product: 698890
fast: false
reactant: 698854
reversible: false
is: ENSECAG00000006455.1

698914
type: SpeciesReference
stoichiometry: 1.0
species: 586192

586192
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _4,4-dimethylcholesta-8,14,24-trienol_C29H46O

698902
type: SpeciesReference
stoichiometry: 3.0
species: 605418

698878
type: SpeciesReference
stoichiometry: 1.0
species: 596660

596660
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Formate_CH1O2

698830
type: SpeciesReference
stoichiometry: 3.0
species: 606008

606008
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: O2_O2

698842
type: SpeciesReference
stoichiometry: 1.0
species: 603000

603000
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Lanosterol_C30H50O

698866
type: SpeciesReference
stoichiometry: 2.0
species: 599605

698890
type: SpeciesReference
stoichiometry: 4.0
species: 599493

698854
type: SpeciesReference
stoichiometry: 3.0
species: 605479

611150
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: testosterone glucuronide_C25H36O8

014165
type: Reaction
is: ENSECAG00000014732.1
product: 664581
product: 664593
fast: false
product: 664641
product: 664629
product: 664605
reactant: 664471
notes: R_PCFLOPm subsystem: Transport, Mitochondrial R_PCFLOPm equation: atp[c] + h2o[c] + pchol_hs[m] --> adp[c] + h[c] + pchol_hs[c] + pi[c] R_PSFLIP subsystem: Transport, Extracellular R_PSFLIP equation: atp[c] + h2o[c] + ps_hs[e] --> adp[c] + h[c] + pi[c] + ps_hs[c] R_PEFLIP subsystem: Transport, Extracellular R_PEFLIP equation: atp[c] + h2o[c] + pe_hs[e] --> adp[c] + h[c] + pe_hs[c] + pi[c] R_PSFLIPm subsystem: Transport, Mitochondrial R_PSFLIPm equation: atp[c] + h2o[c] + ps_hs[c] --> adp[c] + h[c] + pi[c] + ps_hs[m] R_PEFLIPm subsystem: Transport, Mitochondrial R_PEFLIPm equation: atp[c] + h2o[c] + pe_hs[c] --> adp[c] + h[c] + pe_hs[m] + pi[c]
product: 664617
reactant: 664545
product: 664557
reversible: false
product: 664569
reactant: 664508
reactant: 664484
reactant: 664496
reactant: 664533
reactant: 664521

664581
type: SpeciesReference
stoichiometry: 1.0
species: 607135

607135
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2

664593
type: SpeciesReference
stoichiometry: 1.0
species: 607110

607110
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2

664641
type: SpeciesReference
stoichiometry: 1.0
species: 608404

664629
type: SpeciesReference
stoichiometry: 5.0
species: 599531

664605
type: SpeciesReference
stoichiometry: 5.0
species: 589206

664471
type: SpeciesReference
stoichiometry: 5.0
species: 590727

664617
type: SpeciesReference
stoichiometry: 1.0
species: 608428

608428
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: phosphatidylserine (homo sapiens)_C6H11NO6PFULLRCO2FULLR2CO2

664545
type: SpeciesReference
stoichiometry: 1.0
species: 608404

664557
type: SpeciesReference
stoichiometry: 5.0
species: 607462

664569
type: SpeciesReference
stoichiometry: 1.0
species: 606965

664508
type: SpeciesReference
stoichiometry: 5.0
species: 599421

664484
type: SpeciesReference
stoichiometry: 1.0
species: 607110

664496
type: SpeciesReference
stoichiometry: 1.0
species: 607122

607122
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2

664533
type: SpeciesReference
stoichiometry: 1.0
species: 607001

607001
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

664521
type: SpeciesReference
stoichiometry: 1.0
species: 608416

608416
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: phosphatidylserine (homo sapiens)_C6H11NO6PFULLRCO2FULLR2CO2

603132
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: w-hydroxyl leukotriene B4_C20H31O5

596213
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Ethanolamine phosphate_C2H7NO4P

609100
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: sialyl-T antigen_C25H40N2O18X

609800
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: starch, structure 1 (1,6-{7[1,4-Glc], 4[1,4-Glc]})_C66H112O56

602373
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate II (core 2-linked), degradation product 1_C70H113N5O59S3X

607631
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: (R)-Pantothenate_C9H16NO5

586156
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Ureidoisobutyrate_C5H9N2O3

593341
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: chondroitin sulfate precursor (GalNAc-GlcA-(Gal)2-Xyl-L-Ser (protein))_C31H49NO25X

588360
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Acetaldehyde_C2H4O

009439
type: Reaction
reactant: 620431
product: 620467
reversible: true
is: http://identifiers.org/ec-code/1.11.1.9
name: glutathione peroxidase, mitochondria
reactant: 620443
notes: R_GTHPm subsystem: Glutathione Metabolism R_GTHPm equation: [m] : (2) gthrd + h2o2 <==> gthox + (2) h2o
is: ENSECAG00000002762.1
is: ENSECAG00000017026.1
product: 620455
fast: false

620431
type: SpeciesReference
stoichiometry: 1.0
species: 599385

599385
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Hydrogen peroxide_H2O2

620467
type: SpeciesReference
stoichiometry: 1.0
species: 599180

599180
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Oxidized glutathione_C20H30N6O12S2

620443
type: SpeciesReference
stoichiometry: 2.0
species: 599216

599216
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Reduced glutathione_C10H16N3O6S

620455
type: SpeciesReference
stoichiometry: 2.0
species: 599469

009005
type: Reaction
is: ENSECAG00000008611.1
reactant: 616756
notes: R_PDHm subsystem: Glycolysis/Gluconeogenesis R_PDHm equation: [m] : coa + nad + pyr --> accoa + co2 + nadh R_2OXOADOXm subsystem: Lysine Metabolism R_2OXOADOXm equation: [m] : 2oxoadp + coa + nad --> co2 + glutcoa + nadh R_AKGDm subsystem: Citric Acid Cycle R_AKGDm equation: [m] : akg + coa + nad --> co2 + nadh + succoa
reactant: 616731
product: 616805
reactant: 616744
product: 616793
is: http://identifiers.org/ec-code/1.2.4.1
fast: false
reactant: 616768
reversible: false
product: 616817
product: 616830
is: http://identifiers.org/ec-code/1.2.4.2
product: 616781
reactant: 616718

616756
type: SpeciesReference
stoichiometry: 1.0
species: 608665

616731
type: SpeciesReference
stoichiometry: 3.0
species: 592378

616805
type: SpeciesReference
stoichiometry: 3.0
species: 592294

616744
type: SpeciesReference
stoichiometry: 1.0
species: 589712

616793
type: SpeciesReference
stoichiometry: 1.0
species: 609957

616768
type: SpeciesReference
stoichiometry: 3.0
species: 605272

616817
type: SpeciesReference
stoichiometry: 1.0
species: 598398

616830
type: SpeciesReference
stoichiometry: 3.0
species: 605334

616781
type: SpeciesReference
stoichiometry: 1.0
species: 588432

616718
type: SpeciesReference
stoichiometry: 1.0
species: 585319

010290
type: Reaction
reversible: false
product: 628597
product: 628609
reactant: 628561
name: heparin-glucosamine 3-O-sulfotransferase
is: ENSECAG00000020468.1
reactant: 628573
fast: false
is: http://identifiers.org/ec-code/2.8.2.23
product: 628585
notes: R_S3T1g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T1g equation: [g] : hs_pre13 + paps --> h + hs_pre14 + pap

628597
type: SpeciesReference
stoichiometry: 1.0
species: 600635

600635
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: heparan sulfate, precursor 14_C79H115N5O95S10X

628609
type: SpeciesReference
stoichiometry: 1.0
species: 606929

628561
type: SpeciesReference
stoichiometry: 1.0
species: 606953

628573
type: SpeciesReference
stoichiometry: 1.0
species: 600623

628585
type: SpeciesReference
stoichiometry: 1.0
species: 599556

013912
type: Reaction
is: http://identifiers.org/ec-code/3.1.2.6
product: 661763
product: 661811
reversible: false
reactant: 661739
product: 661775
product: 661823
reactant: 661714
is: ENSECAG00000005471.1
reactant: 661751
product: 661787
fast: false
notes: R_GLYOX subsystem: Pyruvate Metabolism R_GLYOX equation: [c] : h2o + lgt-S --> gthrd + h + lac-D R_GLYOXm subsystem: Pyruvate Metabolism R_GLYOXm equation: [m] : h2o + lgt-S --> gthrd + h + lac-D
product: 661799
reactant: 661727

661763
type: SpeciesReference
stoichiometry: 1.0
species: 602892

602892
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: D-Lactate_C3H5O3

661811
type: SpeciesReference
stoichiometry: 1.0
species: 602868

661739
type: SpeciesReference
stoichiometry: 1.0
species: 599421

661775
type: SpeciesReference
stoichiometry: 1.0
species: 599192

661823
type: SpeciesReference
stoichiometry: 1.0
species: 599531

661714
type: SpeciesReference
stoichiometry: 1.0
species: 599469

661751
type: SpeciesReference
stoichiometry: 1.0
species: 603288

661787
type: SpeciesReference
stoichiometry: 1.0
species: 599216

661799
type: SpeciesReference
stoichiometry: 1.0
species: 599581

661727
type: SpeciesReference
stoichiometry: 1.0
species: 603276

603276
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: (R)-S-Lactoylglutathione_C13H20N3O8S

604730
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: _1D-myo-Inositol 1,4,5,6-tetrakisphosphate_C6H8O18P4

590992
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Bilirubin_C33H34N4O6

609280
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Selenohomocysteine_C4H9NO2Se

588494
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Acetone_C3H6O

590451
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: arachidonic acid_C20H31O2

011014
type: Reaction
is: http://identifiers.org/ec-code/1.13.11.31
reversible: false
is: ENSECAG00000022015.1
product: 635260
name: Arachidonate 12-lipoxygenase
reactant: 635236
notes: R_ALOX12 subsystem: Eicosanoid Metabolism R_ALOX12 equation: [c] : arachd + o2 --> 12HPET
reactant: 635248
fast: false

635260
type: SpeciesReference
stoichiometry: 1.0
species: 584677

635236
type: SpeciesReference
stoichiometry: 1.0
species: 590439

635248
type: SpeciesReference
stoichiometry: 1.0
species: 605960

590379
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: arachidyl coenzyme A_C41H70N7O17P3S

015583
type: Reaction
reactant: 677503
reversible: false
modifier: 677840
notes: R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD19x_LPAREN_P_RPAREN_ subsystem: Phenylalanine metabolism R_ALDD19x_LPAREN_P_RPAREN_ equation: [c] : h2o + nadp + pacald --> (2) h + nadph + pac R_3MOX4HOXPGALDOX subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX equation: [c] : 3m4hpga + h2o + nad --> 3mox4hoxm + (2) h + nadh R_MACOXO subsystem: Histidine Metabolism R_MACOXO equation: [c] : 3mldz + h2o + nad --> 3mlda + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_4HOXPACDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_4HOXPACDOX_LPAREN_NADP_RPAREN_ equation: [c] : 4hoxpacd + h2o + nadp <==> 4hphac + (2) h + nadph R_3M4HDXPAC subsystem: Tyrosine metabolism R_3M4HDXPAC equation: [c] : 3mox4hpac + h2o + nad <==> (2) h + homoval + nadh R_34DHPLACOX subsystem: Tyrosine metabolism R_34DHPLACOX equation: [c] : 34dhpac + h2o + nad --> 34dhpha + (2) h + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ equation: [c] : 3m4hpga + h2o + nadp <==> 3mox4hoxm + (2) h + nadph R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_ALDD19x subsystem: Phenylalanine metabolism R_ALDD19x equation: [c] : h2o + nad + pacald --> (2) h + nadh + pac R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh R_34DHXMANDACOX subsystem: Tyrosine metabolism R_34DHXMANDACOX equation: [c] : 34dhmald + h2o + nad --> 34dhoxmand + (2) h + nadh
product: 677636
product: 677623
product: 677672
product: 677587
product: 677599
modifier: 677816
modifier: 677852
modifier: 677828
modifier: 677768
modifier: 677864
is: http://identifiers.org/ec-code/1.2.1.39
modifier: 677780
reactant: 677443
modifier: 677792
reactant: 677455
modifier: 677744
fast: false
reactant: 677539
product: 677720
modifier: 677756
is: http://identifiers.org/ec-code/1.2.1.21
reactant: 677431
reactant: 677515
is: ENSECAG00000021048.1
product: 677684
product: 677575
reactant: 677491
product: 677648
reactant: 677467
is: ENSECAG00000008871.1
reactant: 677479
modifier: 677732
reactant: 677527
reactant: 677551
product: 677611
product: 677708
product: 677696
reactant: 677563
product: 677660
reactant: 677419
is: http://identifiers.org/ec-code/1.2.1.5
is: http://identifiers.org/ec-code/1.2.1.3
modifier: 677804

677503
type: SpeciesReference
stoichiometry: 1.0
species: 605370

585938
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Methoxy-4-hydroxymandelate_C9H9O5

677636
type: SpeciesReference
stoichiometry: 1.0
species: 585864

677623
type: SpeciesReference
stoichiometry: 1.0
species: 585415

677672
type: SpeciesReference
stoichiometry: 1.0
species: 602868

677587
type: SpeciesReference
stoichiometry: 1.0
species: 588264

677599
type: SpeciesReference
stoichiometry: 1.0
species: 598157

598157
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Glucarate_C6H8O8

677443
type: SpeciesReference
stoichiometry: 10.0
species: 605248

677455
type: SpeciesReference
stoichiometry: 1.0
species: 597771

597771
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Glycolaldehyde_C2H4O2

600176
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Homovanillate_C9H9O4

677539
type: SpeciesReference
stoichiometry: 1.0
species: 598073

598073
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-glucurono-6,3-lactone_C6H8O6

677720
type: SpeciesReference
stoichiometry: 10.0
species: 605322

677431
type: SpeciesReference
stoichiometry: 1.0
species: 602964

677515
type: SpeciesReference
stoichiometry: 2.0
species: 606636

677684
type: SpeciesReference
stoichiometry: 23.0
species: 599531

677575
type: SpeciesReference
stoichiometry: 1.0
species: 598626

598626
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Glycolate_C2H3O3

677491
type: SpeciesReference
stoichiometry: 1.0
species: 585828

677648
type: SpeciesReference
stoichiometry: 2.0
species: 606624

606624
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Phenylacetic acid_C8H7O2

677467
type: SpeciesReference
stoichiometry: 1.0
species: 588360

677479
type: SpeciesReference
stoichiometry: 1.0
species: 585403

677527
type: SpeciesReference
stoichiometry: 12.0
species: 599421

677551
type: SpeciesReference
stoichiometry: 1.0
species: 602940

677611
type: SpeciesReference
stoichiometry: 1.0
species: 585379

585379
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3,4-Dihydroxymandelate_C8H7O5

677708
type: SpeciesReference
stoichiometry: 1.0
species: 605442

677696
type: SpeciesReference
stoichiometry: 1.0
species: 585938

677563
type: SpeciesReference
stoichiometry: 1.0
species: 585367

677660
type: SpeciesReference
stoichiometry: 1.0
species: 602904

677419
type: SpeciesReference
stoichiometry: 1.0
species: 585876

586424
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _4-Hydroxyphenylacetate_C8H7O3

017024
type: Reaction
is: ENSECAG00000013103.1
notes: R_RETH subsystem: Vitamin A Metabolism R_RETH equation: [c] : h2o + retfa --> Rtotal2 + h + retinol
fast: false
reversible: false
product: 691795
product: 691771
product: 691783
reactant: 691747
name: retinyl ester hydrolase
reactant: 691759

691795
type: SpeciesReference
stoichiometry: 1.0
species: 599531

691771
type: SpeciesReference
stoichiometry: 1.0
species: 608883

691783
type: SpeciesReference
stoichiometry: 1.0
species: 587803

691747
type: SpeciesReference
stoichiometry: 1.0
species: 608786

608786
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: fatty acid retinol_C20H29OFULLR2CO

691759
type: SpeciesReference
stoichiometry: 1.0
species: 599421

597324
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: D-Glucose 6-phosphate_C6H11O9P

609436
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-sulfolactate_C3H4O6S

016628
type: Reaction
name: Beta-1,3-galactosyltransferase 5
product: 689035
reactant: 688998
product: 689022
reactant: 689010
product: 689047
notes: R_B3GALT5g subsystem: Sphingolipid Metabolism R_B3GALT5g equation: [g] : gbside_hs + udpgal --> galgbside_hs + h + udp
is: ENSECAG00000004805.1
fast: false
reversible: false

689035
type: SpeciesReference
stoichiometry: 1.0
species: 611417

688998
type: SpeciesReference
stoichiometry: 1.0
species: 597747

597747
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: globoside (homo sapiens)_C44H79N2O22FULLRCO

689022
type: SpeciesReference
stoichiometry: 1.0
species: 597602

689010
type: SpeciesReference
stoichiometry: 1.0
species: 611574

689047
type: SpeciesReference
stoichiometry: 1.0
species: 599556

591162
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Butyrate (n-C4:0)_C4H7O2

015979
type: Reaction
is: ENSECAG00000013178.1
product: 682879
reactant: 682831
product: 682843
is: http://identifiers.org/ec-code/2.7.1.30
product: 682891
product: 682855
product: 682903
reactant: 682807
is: ENSECAG00000022334.1
reversible: false
fast: false
notes: R_GLYKm subsystem: Glycerophospholipid Metabolism R_GLYKm equation: [m] : atp + glyc --> adp + glyc3p + h R_GLYK subsystem: Glycerophospholipid Metabolism R_GLYK equation: [c] : atp + glyc --> adp + glyc3p + h
reactant: 682795
reactant: 682819
is: ENSECAG00000003599.1
product: 682867

682879
type: SpeciesReference
stoichiometry: 1.0
species: 598542

682831
type: SpeciesReference
stoichiometry: 1.0
species: 598590

682843
type: SpeciesReference
stoichiometry: 1.0
species: 598554

598554
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Glycerol 3-phosphate_C3H7O6P

682891
type: SpeciesReference
stoichiometry: 1.0
species: 599531

682855
type: SpeciesReference
stoichiometry: 1.0
species: 589230

682903
type: SpeciesReference
stoichiometry: 1.0
species: 599581

682807
type: SpeciesReference
stoichiometry: 1.0
species: 598614

598614
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Glycerol_C3H8O3

682795
type: SpeciesReference
stoichiometry: 1.0
species: 590727

682819
type: SpeciesReference
stoichiometry: 1.0
species: 590751

682867
type: SpeciesReference
stoichiometry: 1.0
species: 589206

612436
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane_C27H48O3

016641
type: Reaction
reversible: false
is: ENSECAG00000016504.1
reactant: 689083
reactant: 689071
is: http://identifiers.org/ec-code/2.6.1.1
modifier: 689251
is: http://identifiers.org/ec-code/2.6.1.21
product: 689119
is: http://identifiers.org/ec-code/2.6.1.58
fast: false
modifier: 689300
product: 689155
modifier: 689179
product: 689143
product: 689131
modifier: 689288
reactant: 689107
modifier: 689276
modifier: 689167
is: http://identifiers.org/ec-code/2.6.1.5
notes: R_EHGLAT2m subsystem: Arginine and Proline Metabolism R_EHGLAT2m equation: [m] : e4hglu + oaa --> 4h2oglt + asp-L R_TYRTAm subsystem: Tyrosine metabolism R_TYRTAm equation: [m] : akg + tyr-L <==> 34hpp + glu-L R_PHETA1m subsystem: Phenylalanine metabolism R_PHETA1m equation: [m] : akg + phe-L <==> glu-L + phpyr R_LCYSTATm subsystem: Cysteine Metabolism R_LCYSTATm equation: [m] : Lcyst + akg <==> 3spyr + glu-L R_CYSTAm subsystem: Cysteine Metabolism R_CYSTAm equation: [m] : akg + cys-L <==> glu-L + mercppyr R_ASPTAm subsystem: Alanine and Aspartate Metabolism R_ASPTAm equation: [m] : akg + asp-L <==> glu-L + oaa R_EHGLATm subsystem: Arginine and Proline Metabolism R_EHGLATm equation: [m] : akg + e4hglu --> 4h2oglt + glu-L R_3SALATAim subsystem: Cysteine Metabolism R_3SALATAim equation: [m] : 3sala + akg + h --> 3snpyr + glu-L
modifier: 689203
modifier: 689239
is: http://identifiers.org/ec-code/2.6.1.3
reactant: 689095
reactant: 689059
modifier: 689191
modifier: 689227
modifier: 689264
modifier: 689215

689083
type: SpeciesReference
stoichiometry: 2.0
species: 595702

595702
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-erythro-4-Hydroxyglutamate_C5H8NO5

689071
type: SpeciesReference
stoichiometry: 1.0
species: 586095

689119
type: SpeciesReference
stoichiometry: 2.0
species: 598301

611357
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Tyrosine_C9H11NO3

689155
type: SpeciesReference
stoichiometry: 1.0
species: 590715

689143
type: SpeciesReference
stoichiometry: 1.0
species: 586119

586119
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _3-Sulfinopyruvate_C3H2O5S

689131
type: SpeciesReference
stoichiometry: 2.0
species: 586363

586363
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: _4-Hydroxy-2-oxoglutarate_C5H4O6

689107
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species: 599581

586144
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _3-Sulfopyruvate_C3H2O6S

689095
type: SpeciesReference
stoichiometry: 2.0
species: 589712

689059
type: SpeciesReference
stoichiometry: 1.0
species: 606106

607316
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Phenylalanine_C9H11NO2

604523
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Mercaptopyruvate_C3H3O3S

609982
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Succinic semialdehyde_C4H5O3

607037
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Procollagen L-lysine_C7H14N3O2R2

589278
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: ADPglucose_C16H23N5O15P2

595012
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dimethylallyl diphosphate_C5H9O7P2

009830
type: Reaction
is: ENSECAG00000008450.1
fast: false
is: ENSECAG00000023293.1
is: http://identifiers.org/ec-code/3.6.3.6
is: ENSECAG00000024436.1
product: 623684
name: Ca ATPase
notes: R_CAATPS subsystem: Transport, Extracellular R_CAATPS equation: atp[c] + (2) ca2[c] + h2o[c] --> adp[c] + (2) ca2[e] + h[e] + pi[c]
product: 623672
is: ENSECAG00000023490.1
reactant: 623636
reversible: false
product: 623660
reactant: 623624
reactant: 623612
product: 623648
is: ENSECAG00000023528.1

623684
type: SpeciesReference
stoichiometry: 1.0
species: 607462

623672
type: SpeciesReference
stoichiometry: 1.0
species: 599544

623636
type: SpeciesReference
stoichiometry: 1.0
species: 590727

623660
type: SpeciesReference
stoichiometry: 2.0
species: 591295

591295
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Calcium_Ca

623624
type: SpeciesReference
stoichiometry: 1.0
species: 599421

623612
type: SpeciesReference
stoichiometry: 2.0
species: 591283

591283
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Calcium_Ca

623648
type: SpeciesReference
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species: 589206

584943
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: L-1-Pyrroline-3-hydroxy-5-carboxylate_C5H6NO3

601611
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 26_C110H179N7O93S4

594820
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: dITP_C10H11N4O13P3

013055
type: Reaction
is: ENSECAG00000020700.1
product: 652679
notes: R_INOSTO subsystem: Inositol Phosphate Metabolism R_INOSTO equation: [c] : inost + o2 --> glcur + h + h2o
reactant: 652667
reversible: false
is: http://identifiers.org/ec-code/1.13.99.1
name: inositol oxygenase
fast: false
product: 652703
reactant: 652654
product: 652691

652679
type: SpeciesReference
stoichiometry: 1.0
species: 598181

598181
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Glucuronate_C6H9O7

652667
type: SpeciesReference
stoichiometry: 1.0
species: 605960

652703
type: SpeciesReference
stoichiometry: 1.0
species: 599531

652654
type: SpeciesReference
stoichiometry: 1.0
species: 601166

652691
type: SpeciesReference
stoichiometry: 1.0
species: 599421

592956
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 1_C45H68N2O43S2

586640
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: _4-Trimethylammoniobutanal_C7H16NO

015679
type: Reaction
product: 679002
reactant: 678757
product: 679078
product: 678927
reactant: 678744
notes: R_G14Tg subsystem: N-Glycan Biosynthesis R_G14Tg equation: [g] : fn2m2masn + (2) udpgal --> (2) h + l2fn2m2masn + (2) udp R_G14T7g subsystem: Keratan sulfate biosynthesis R_G14T7g equation: [g] : ksi_pre5 + udpgal --> h + ksi_pre6 + udp R_G14T21g subsystem: Keratan sulfate biosynthesis R_G14T21g equation: [g] : ksii_core4_pre9 + udpgal --> h + ksii_core4_pre10 + udp R_G14T13g subsystem: Keratan sulfate biosynthesis R_G14T13g equation: [g] : ksi_pre23 + udpgal --> h + ksi_pre24 + udp R_G14T17g subsystem: Keratan sulfate biosynthesis R_G14T17g equation: [g] : ksi_pre35 + udpgal --> h + ksi_pre36 + udp R_G14T20g subsystem: Keratan sulfate biosynthesis R_G14T20g equation: [g] : ksii_core4_pre6 + udpgal --> h + ksii_core4_pre7 + udp R_G14T16g subsystem: Keratan sulfate biosynthesis R_G14T16g equation: [g] : ksi_pre32 + udpgal --> h + ksi_pre33 + udp R_G14T3g subsystem: Keratan sulfate biosynthesis R_G14T3g equation: [g] : ksii_core2_pre3 + udpgal --> h + ksii_core2_pre4 + udp R_UGALGTg subsystem: Galactose metabolism R_UGALGTg equation: [g] : glc-D + udpgal --> h + lcts + udp R_G14T10g subsystem: Keratan sulfate biosynthesis R_G14T10g equation: [g] : ksi_pre14 + udpgal --> h + ksi_pre15 + udp R_G14T12g subsystem: Keratan sulfate biosynthesis R_G14T12g equation: [g] : ksi_pre20 + udpgal --> h + ksi_pre21 + udp R_G14T15g subsystem: Keratan sulfate biosynthesis R_G14T15g equation: [g] : ksi_pre29 + udpgal --> h + ksi_pre30 + udp R_G14T9g subsystem: Keratan sulfate biosynthesis R_G14T9g equation: [g] : ksi_pre11 + udpgal --> h + ksi_pre12 + udp R_G14T2g subsystem: Keratan sulfate biosynthesis R_G14T2g equation: [g] : ksii_core2_pre1 + udpgal --> h + ksii_core2_pre2 + udp R_G14T6g subsystem: Keratan sulfate biosynthesis R_G14T6g equation: [g] : ksi_pre2 + udpgal --> h + ksi_pre3 + udp R_G14T19g subsystem: Keratan sulfate biosynthesis R_G14T19g equation: [g] : ksii_core4_pre3 + udpgal --> h + ksii_core4_pre4 + udp R_G14T4g subsystem: Keratan sulfate biosynthesis R_G14T4g equat…
is: http://identifiers.org/ec-code/2.4.1.22
product: 678939
product: 679103
product: 679115
product: 679091
reactant: 678842
reactant: 678830
product: 679127
reactant: 678708
reactant: 678635
reactant: 678793
product: 679139
fast: false
reactant: 678660
reactant: 678598
product: 678878
reactant: 678696
product: 679028
reactant: 678622
reactant: 678610
reactant: 678818
product: 678951
product: 678903
product: 678891
product: 679015
product: 678915
product: 679041
reactant: 678854
product: 679151
product: 678964
reactant: 678781
reactant: 678684
product: 678866
product: 678976
is: http://identifiers.org/ec-code/2.4.1.38
reactant: 678586
reactant: 678647
reactant: 678769
reactant: 678672
product: 678989
is: ENSECAG00000011805.1
reversible: false
reactant: 678806
product: 679054
reactant: 678732
reactant: 678720
product: 679066
is: ENSECAG00000005500.1

679002
type: SpeciesReference
stoichiometry: 24.0
species: 599556

678757
type: SpeciesReference
stoichiometry: 1.0
species: 602543

679078
type: SpeciesReference
stoichiometry: 1.0
species: 602275

678927
type: SpeciesReference
stoichiometry: 1.0
species: 602118

678744
type: SpeciesReference
stoichiometry: 1.0
species: 602226

678939
type: SpeciesReference
stoichiometry: 1.0
species: 601961

679103
type: SpeciesReference
stoichiometry: 1.0
species: 602748

679115
type: SpeciesReference
stoichiometry: 1.0
species: 602555

679091
type: SpeciesReference
stoichiometry: 1.0
species: 602530

678842
type: SpeciesReference
stoichiometry: 1.0
species: 602616

678830
type: SpeciesReference
stoichiometry: 24.0
species: 611574

679127
type: SpeciesReference
stoichiometry: 1.0
species: 602506

678708
type: SpeciesReference
stoichiometry: 1.0
species: 602579

678635
type: SpeciesReference
stoichiometry: 1.0
species: 602022

678793
type: SpeciesReference
stoichiometry: 1.0
species: 602262

679139
type: SpeciesReference
stoichiometry: 1.0
species: 602323

678660
type: SpeciesReference
stoichiometry: 1.0
species: 601949

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type: SpeciesReference
stoichiometry: 1.0
species: 592462

678878
type: SpeciesReference
stoichiometry: 1.0
species: 602700

678696
type: SpeciesReference
stoichiometry: 1.0
species: 598121

598121
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: D-Glucose_C6H12O6

679028
type: SpeciesReference
stoichiometry: 1.0
species: 602034

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type: SpeciesReference
stoichiometry: 1.0
species: 602311

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type: SpeciesReference
stoichiometry: 1.0
species: 602808

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type: SpeciesReference
stoichiometry: 1.0
species: 602348

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type: SpeciesReference
stoichiometry: 1.0
species: 603024

603024
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Lactose_C12H22O11

678903
type: SpeciesReference
stoichiometry: 1.0
species: 602287

678891
type: SpeciesReference
stoichiometry: 1.0
species: 602154

679015
type: SpeciesReference
stoichiometry: 1.0
species: 602238

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type: SpeciesReference
stoichiometry: 1.0
species: 602784

679041
type: SpeciesReference
stoichiometry: 1.0
species: 602361

678854
type: SpeciesReference
stoichiometry: 1.0
species: 602772

679151
type: SpeciesReference
stoichiometry: 1.0
species: 602082

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type: SpeciesReference
stoichiometry: 1.0
species: 602712

678781
type: SpeciesReference
stoichiometry: 1.0
species: 602070

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type: SpeciesReference
stoichiometry: 1.0
species: 602178

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type: SpeciesReference
stoichiometry: 1.0
species: 602202

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type: SpeciesReference
stoichiometry: 24.0
species: 611417

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type: SpeciesReference
stoichiometry: 1.0
species: 602736

678647
type: SpeciesReference
stoichiometry: 1.0
species: 601986

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type: SpeciesReference
stoichiometry: 1.0
species: 602518

678672
type: SpeciesReference
stoichiometry: 1.0
species: 596552

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type: SpeciesReference
stoichiometry: 1.0
species: 602820

678806
type: SpeciesReference
stoichiometry: 1.0
species: 602106

679054
type: SpeciesReference
stoichiometry: 1.0
species: 602591

678732
type: SpeciesReference
stoichiometry: 1.0
species: 602190

678720
type: SpeciesReference
stoichiometry: 1.0
species: 602142

679066
type: SpeciesReference
stoichiometry: 1.0
species: 601998

606685
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)_C9H13O18P4FULLRCO2FULLR2CO2

017325
type: Reaction
product: 694831
reactant: 694638
is: ENSECAG00000021048.1
reactant: 694674
product: 694843
product: 694771
reactant: 694723
is: http://identifiers.org/ec-code/1.2.1.3
fast: false
product: 694735
reactant: 694626
reactant: 694662
product: 694855
product: 694867
product: 694783
product: 694807
product: 694747
is: ENSECAG00000019343.1
product: 694795
reactant: 694711
reactant: 694687
reactant: 694578
reactant: 694699
product: 694819
product: 694759
is: http://identifiers.org/ec-code/1.2.1.21
reactant: 694590
product: 694879
reactant: 694602
reactant: 694614
reactant: 694650
notes: R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD20x subsystem: Tryptophan metabolism R_ALDD20x equation: [c] : h2o + id3acald + nad --> (2) h + ind3ac + nadh R_BAMPPALDOX subsystem: beta-Alanine metabolism R_BAMPPALDOX equation: [c] : bamppald + h2o + nad --> ala-B + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_IMACTD subsystem: Histidine Metabolism R_IMACTD equation: [c] : h2o + im4act + nad --> (2) h + im4ac + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_PYLALDOX subsystem: Limonene and pinene degradation R_PYLALDOX equation: [c] : h2o + nad + pylald --> (2) h + nadh + peracd R_NABTNO subsystem: Arginine and Proline Metabolism R_NABTNO equation: [c] : h2o + n4abutn + nad --> 4aabutn + (2) h + nadh R_5HOXINDACTOX subsystem: Tryptophan metabolism R_5HOXINDACTOX equation: [c] : 5hoxindact + h2o + nad --> 5hoxindoa + (2) h + nadh R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh
reversible: false

694831
type: SpeciesReference
stoichiometry: 1.0
species: 607220

607220
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Perillic acid_C10H13O2

694638
type: SpeciesReference
stoichiometry: 1.0
species: 597771

694674
type: SpeciesReference
stoichiometry: 1.0
species: 586960

694843
type: SpeciesReference
stoichiometry: 1.0
species: 589748

589748
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: beta-Alanine_C3H7NO2

694771
type: SpeciesReference
stoichiometry: 1.0
species: 588264

694723
type: SpeciesReference
stoichiometry: 1.0
species: 602940

694735
type: SpeciesReference
stoichiometry: 1.0
species: 601069

601069
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Imidazole-4-acetate_C5H5N2O2

694626
type: SpeciesReference
stoichiometry: 11.0
species: 605248

694662
type: SpeciesReference
stoichiometry: 1.0
species: 590823

590823
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: beta-Aminopropion aldehyde_C3H8NO

694855
type: SpeciesReference
stoichiometry: 1.0
species: 602868

694867
type: SpeciesReference
stoichiometry: 23.0
species: 599531

694783
type: SpeciesReference
stoichiometry: 1.0
species: 586240

586240
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _4-Acetamidobutanoate_C6H10NO3

694807
type: SpeciesReference
stoichiometry: 1.0
species: 586984

586984
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5-Hydroxyindoleacetate_C10H8NO3

694747
type: SpeciesReference
stoichiometry: 1.0
species: 598626

694795
type: SpeciesReference
stoichiometry: 1.0
species: 598157

694711
type: SpeciesReference
stoichiometry: 1.0
species: 598073

694687
type: SpeciesReference
stoichiometry: 1.0
species: 600936

694578
type: SpeciesReference
stoichiometry: 1.0
species: 602964

694699
type: SpeciesReference
stoichiometry: 12.0
species: 599421

694819
type: SpeciesReference
stoichiometry: 1.0
species: 602904

694759
type: SpeciesReference
stoichiometry: 1.0
species: 601141

601141
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Indole-3-acetate_C10H8NO2

694590
type: SpeciesReference
stoichiometry: 1.0
species: 605151

694879
type: SpeciesReference
stoichiometry: 11.0
species: 605322

694602
type: SpeciesReference
stoichiometry: 1.0
species: 601093

601093
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Imidazole-4-acetaldehyde_C5H6N2O

694614
type: SpeciesReference
stoichiometry: 1.0
species: 608616

608616
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Perillyl aldehyde_C10H14O

694650
type: SpeciesReference
stoichiometry: 1.0
species: 588360

610043
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: triacylglycerol (homo sapiens)_C3H5FULLRCO2FULLR2CO2FULLR3CO2

018250
type: Reaction
product: 702990
reactant: 702978
notes: R_ACONTm subsystem: Citric Acid Cycle R_ACONTm equation: [m] : cit <==> icit
is: ENSECAG00000023762.1
is: http://identifiers.org/ec-code/4.2.1.3
fast: false
reversible: true
name: Aconitate hydratase

702990
type: SpeciesReference
stoichiometry: 1.0
species: 600912

600912
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Isocitrate_C6H5O7

702978
type: SpeciesReference
stoichiometry: 1.0
species: 591989

591989
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Citrate_C6H5O7

598037
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: GDP-D-mannose_C16H23N5O16P2

585694
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401

612289
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _7alpha-Hydroxycholest-4-en-3-one_C27H44O2

009926
type: Reaction
reactant: 625061
is: http://identifiers.org/ec-code/2.7.7.41
reversible: false
fast: false
is: ENSECAG00000011962.1
notes: R_CDS subsystem: Glycerophospholipid Metabolism R_CDS equation: [c] : ctp + h + pa_hs --> cdpdag_hs + ppi
reactant: 625085
product: 625109
product: 625097
name: phosphatidate cytidylyltransferase
reactant: 625073

625061
type: SpeciesReference
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species: 606564

625085
type: SpeciesReference
stoichiometry: 1.0
species: 593439

593439
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: CTP_C9H12N3O14P3

625109
type: SpeciesReference
stoichiometry: 1.0
species: 607728

625097
type: SpeciesReference
stoichiometry: 1.0
species: 591531

625073
type: SpeciesReference
stoichiometry: 1.0
species: 599531

596408
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Formaldehyde_CH2O

ORG:
  orgname: University of Missouri - Columbia
n:
  given: Conant
  family: Conant

586580
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-4'-Phosphopantothenate_C9H15NO8P

018743
type: Reaction
is: ENSECAG00000019713.1
is: http://identifiers.org/ec-code/2.5.1.16
product: 708189
reversible: false
reactant: 708141
name: spermidine synthase
reactant: 708153
fast: false
product: 708165
notes: R_SPMS subsystem: Urea cycle/amino group metabolism R_SPMS equation: [c] : ametam + ptrc --> 5mta + h + spmd
product: 708177

708189
type: SpeciesReference
stoichiometry: 1.0
species: 599531

708141
type: SpeciesReference
stoichiometry: 1.0
species: 608519

708153
type: SpeciesReference
stoichiometry: 1.0
species: 590029

708165
type: SpeciesReference
stoichiometry: 1.0
species: 587092

708177
type: SpeciesReference
stoichiometry: 1.0
species: 609678

607946
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Pregnenolone_C21H32O2

596150
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Estrone 3-sulfate_C18H21O5S

587128
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5-Oxoproline_C5H6NO3

605840
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Sulfate derivative of norepinephrine_C8H11NO6S

018551
type: Reaction
reversible: true
product: 706174
reactant: 706150
notes: R_GTHPe subsystem: Glutathione Metabolism R_GTHPe equation: [e] : (2) gthrd + h2o2 <==> gthox + (2) h2o
is: http://identifiers.org/ec-code/1.11.1.9
fast: false
reactant: 706162
is: ENSECAG00000009019.1
name: glutathione peroxidase (e)
product: 706186

706174
type: SpeciesReference
stoichiometry: 1.0
species: 599168

599168
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Oxidized glutathione_C20H30N6O12S2

706150
type: SpeciesReference
stoichiometry: 2.0
species: 599204

599204
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Reduced glutathione_C10H16N3O6S

706162
type: SpeciesReference
stoichiometry: 1.0
species: 599361

599361
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Hydrogen peroxide_H2O2

706186
type: SpeciesReference
stoichiometry: 2.0
species: 599433

012329
type: Reaction
fast: false
product: 646422
product: 646458
reactant: 646398
notes: R_THYOXt subsystem: Transport, Extracellular R_THYOXt equation: hco3[c] + thyox-L[e] <==> hco3[e] + thyox-L[c] R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_TRIODTHYt subsystem: Transport, Extracellular R_TRIODTHYt equation: hco3[c] + triodthy[e] <==> hco3[e] + triodthy[c] R_ESTRADIOLGLCt subsystem: Transport, Extracellular R_ESTRADIOLGLCt equation: estradiolglc[e] + hco3[c] <==> estradiolglc[c] + hco3[e]
product: 646434
reactant: 646374
reactant: 646350
reactant: 646386
is: ENSECAG00000019552.1
reversible: true
reactant: 646362
product: 646446
product: 646410

646422
type: SpeciesReference
stoichiometry: 1.0
species: 595980

646458
type: SpeciesReference
stoichiometry: 4.0
species: 599701

646398
type: SpeciesReference
stoichiometry: 1.0
species: 596138

646434
type: SpeciesReference
stoichiometry: 1.0
species: 610848

646374
type: SpeciesReference
stoichiometry: 1.0
species: 611066

646350
type: SpeciesReference
stoichiometry: 4.0
species: 599689

646386
type: SpeciesReference
stoichiometry: 1.0
species: 595992

646362
type: SpeciesReference
stoichiometry: 1.0
species: 610860

646446
type: SpeciesReference
stoichiometry: 1.0
species: 611054

646410
type: SpeciesReference
stoichiometry: 1.0
species: 596125

ORG:
  orgname: University of Missouri
n:
  given: Michaël
  family: Bekaert

586436
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: trans-4-Hydroxy-L-proline_C5H9NO3

594456
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: _3alpha,7alpha-Dihydroxy-5beta-cholestanate_C27H45O4

597035
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: (Gal)4 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)2 (Cer)1_C84H145N4O50FULLRCO

016270
type: Reaction
modifier: 686530
reactant: 686398
reactant: 686422
modifier: 686494
reversible: false
reactant: 686410
modifier: 686566
product: 686458
product: 686470
reactant: 686434
modifier: 686554
modifier: 686542
is: ENSECAG00000013504.1
fast: false
notes: R_PGLer subsystem: Pentose Phosphate Pathway R_PGLer equation: [r] : 6pgl + h2o --> 6pgc + h R_G6PDH2rer subsystem: Pentose Phosphate Pathway R_G6PDH2rer equation: [r] : g6p + nadp <==> 6pgl + h + nadph R_G6PDH1rer subsystem: Pentose Phosphate Pathway R_G6PDH1rer equation: [r] : g6p + nad <==> 6pgl + h + nadh R_G6PDH1er subsystem: Pentose Phosphate Pathway R_G6PDH1er equation: [r] : g6p + nad --> 6pgl + h + nadh
product: 686446
is: http://identifiers.org/ec-code/3.1.1.31
modifier: 686518
product: 686482
modifier: 686506

686398
type: SpeciesReference
stoichiometry: 1.0
species: 587308

587308
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _6-phospho-D-glucono-1,5-lactone_C6H9O9P

686422
type: SpeciesReference
stoichiometry: 1.0
species: 599493

686410
type: SpeciesReference
stoichiometry: 1.0
species: 597324

686458
type: SpeciesReference
stoichiometry: 1.0
species: 587308

686470
type: SpeciesReference
stoichiometry: 1.0
species: 605346

686434
type: SpeciesReference
stoichiometry: 1.0
species: 605296

686446
type: SpeciesReference
stoichiometry: 1.0
species: 587284

587284
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _6-Phospho-D-gluconate_C6H10O10P

686482
type: SpeciesReference
stoichiometry: 2.0
species: 599605

014370
type: Reaction
notes: R_PPAm subsystem: Oxidative Phosphorylation R_PPAm equation: [m] : h2o + ppi --> h + (2) pi
is: http://identifiers.org/ec-code/3.6.1.1
reactant: 666819
reversible: false
is: ENSECAG00000011236.1
product: 666843
reactant: 666831
product: 666855
name: inorganic diphosphatase
fast: false

666819
type: SpeciesReference
stoichiometry: 1.0
species: 599469

666843
type: SpeciesReference
stoichiometry: 2.0
species: 607510

666831
type: SpeciesReference
stoichiometry: 1.0
species: 607740

666855
type: SpeciesReference
stoichiometry: 1.0
species: 599581

587140
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: (R)-5-Phosphomevalonate_C6H10O7P

012041
type: Reaction
notes: R_DHDPBMTm subsystem: Ubiquinone Biosynthesis R_DHDPBMTm equation: [m] : 3dpdhb + amet --> 3dpdhb_me + ahcys + h R_COQ3m subsystem: Ubiquinone Biosynthesis R_COQ3m equation: [m] : 2dpmhobq + amet --> ahcys + h + q10
reactant: 643451
fast: false
product: 643511
reactant: 643475
reactant: 643463
product: 643523
product: 643499
is: ENSECAG00000016788.1
product: 643487
reversible: false

643451
type: SpeciesReference
stoichiometry: 2.0
species: 589993

589993
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: S-Adenosyl-L-methionine_C15H23N6O5S

643511
type: SpeciesReference
stoichiometry: 1.0
species: 585585

585585
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _3-Decaprenyl-4-hydroxy-5-methoxybenzoate_C58H87O4

643475
type: SpeciesReference
stoichiometry: 1.0
species: 585162

585162
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _2-Decaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone_C58H88O4

643463
type: SpeciesReference
stoichiometry: 1.0
species: 585573

585573
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _3-Decaprenyl-4,5-dihdydroxybenzoate_C57H85O4

643523
type: SpeciesReference
stoichiometry: 2.0
species: 599581

643499
type: SpeciesReference
stoichiometry: 1.0
species: 608702

643487
type: SpeciesReference
stoichiometry: 2.0
species: 589567

589567
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

589362
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: adrenic acid_C22H35O2

012875
type: Reaction
reactant: 651265
product: 651398
reactant: 651326
product: 651374
reversible: false
product: 651386
reactant: 651314
reactant: 651289
fast: false
reactant: 651302
notes: R_H6_APOS_ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6_APOS_ETer equation: [r] : em3gacpail_hs + pe_hs --> dag_hs + em2emgacpail_hs R_H3ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3ETer equation: [r] : m2gacpail_hs + pe_hs --> dag_hs + memgacpail_hs R_H4ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H4ETer equation: [r] : m3gacpail_hs + pe_hs --> dag_hs + m2emgacpail_hs R_H7_APOS_ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7_APOS_ETer equation: [r] : emem2gacpail_hs + pe_hs --> dag_hs + gpi_hs R_H2ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H2ETer equation: [r] : mgacpail_hs + pe_hs --> dag_hs + emgacpail_hs
reactant: 651277
is: ENSECAG00000000728.1
product: 651362
product: 651350
product: 651338

651265
type: SpeciesReference
stoichiometry: 1.0
species: 595920

651398
type: SpeciesReference
stoichiometry: 1.0
species: 595944

595944
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: phosphoethanolaminyl-mannosyl-glucosylaminyl-acylphosphatidylinositol (H5)_C39H74N2O22P2FULLRCO2FULLR2CO2

651326
type: SpeciesReference
stoichiometry: 1.0
species: 604633

651374
type: SpeciesReference
stoichiometry: 5.0
species: 593730

651386
type: SpeciesReference
stoichiometry: 1.0
species: 603734

651314
type: SpeciesReference
stoichiometry: 5.0
species: 607147

651289
type: SpeciesReference
stoichiometry: 1.0
species: 595932

651302
type: SpeciesReference
stoichiometry: 1.0
species: 603746

651277
type: SpeciesReference
stoichiometry: 1.0
species: 603794

651362
type: SpeciesReference
stoichiometry: 1.0
species: 598928

651350
type: SpeciesReference
stoichiometry: 1.0
species: 595896

651338
type: SpeciesReference
stoichiometry: 1.0
species: 604439

608066
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: pristanoyl coa_C40H68N7O17P3S

011378
type: Reaction
is: ENSECAG00000013998.1
reversible: false
product: 637707
reactant: 637659
reactant: 637647
product: 637695
is: http://identifiers.org/ec-code/1.14.99.7
fast: false
notes: R_SQLEr subsystem: Cholesterol Metabolism R_SQLEr equation: [r] : h + nadph + o2 + sql --> Ssq23epx + h2o + nadp
name: Squalene epoxidase, endoplasmic reticular (NADP)
reactant: 637635
reactant: 637671
product: 637683

637707
type: SpeciesReference
stoichiometry: 1.0
species: 605418

637659
type: SpeciesReference
stoichiometry: 1.0
species: 605479

637647
type: SpeciesReference
stoichiometry: 1.0
species: 609702

609702
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Squalene_C30H50

637695
type: SpeciesReference
stoichiometry: 1.0
species: 599493

637635
type: SpeciesReference
stoichiometry: 1.0
species: 606008

637671
type: SpeciesReference
stoichiometry: 1.0
species: 599605

637683
type: SpeciesReference
stoichiometry: 1.0
species: 588106

588106
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: (S)-Squalene-2,3-epoxide_C30H50O

011583
type: Reaction
product: 639950
reversible: false
is: ENSECAG00000014281.1
reactant: 639902
is: ENSECAG00000003276.1
is: http://identifiers.org/ec-code/2.7.9.3
product: 639962
reactant: 639914
notes: R_SELNPS subsystem: Selenoamino acid metabolism R_SELNPS equation: [c] : atp + h2o + seln --> amp + pi + selnp
product: 639938
reactant: 639926
name: Selenophosphate synthase
fast: false

639950
type: SpeciesReference
stoichiometry: 1.0
species: 609316

609316
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Selenophosphate_H2O3PSe

639902
type: SpeciesReference
stoichiometry: 1.0
species: 590727

639962
type: SpeciesReference
stoichiometry: 1.0
species: 590041

639914
type: SpeciesReference
stoichiometry: 1.0
species: 609304

609304
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Selenide_HSe

639938
type: SpeciesReference
stoichiometry: 1.0
species: 607462

639926
type: SpeciesReference
stoichiometry: 1.0
species: 599421

016914
type: Reaction
reactant: 691062
notes: R_GTHP subsystem: Glutathione Metabolism R_GTHP equation: [c] : (2) gthrd + h2o2 <==> gthox + (2) h2o
is: ENSECAG00000008678.1
is: ENSECAG00000002762.1
reversible: true
product: 691098
is: ENSECAG00000011541.1
reactant: 691074
is: http://identifiers.org/ec-code/1.11.1.9
fast: false
product: 691086
name: glutathione peridoxase

691062
type: SpeciesReference
stoichiometry: 1.0
species: 599349

691098
type: SpeciesReference
stoichiometry: 2.0
species: 599421

691074
type: SpeciesReference
stoichiometry: 2.0
species: 599192

691086
type: SpeciesReference
stoichiometry: 1.0
species: 599156

599156
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Oxidized glutathione_C20H30N6O12S2

591113
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Biotin_C10H15N2O3S

587889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: R total 3 position_CO2FULLR3

591052
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: Biocytin_C16H28N4O4S

013151
type: Reaction
name: arginine decarboxylase (m)
product: 653487
is: http://identifiers.org/ec-code/4.1.1.19
fast: false
reactant: 653475
notes: R_ARGDCm subsystem: Arginine and Proline Metabolism R_ARGDCm equation: [m] : arg-L + h --> agm + co2
reversible: false
product: 653499
reactant: 653463
is: ENSECAG00000023032.1

653487
type: SpeciesReference
stoichiometry: 1.0
species: 592294

653475
type: SpeciesReference
stoichiometry: 1.0
species: 599581

653499
type: SpeciesReference
stoichiometry: 1.0
species: 589495

653463
type: SpeciesReference
stoichiometry: 1.0
species: 590571

590571
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Arginine_C6H15N4O2

014971
type: Reaction
fast: false
notes: R_ARGLYSex subsystem: Transport, Extracellular R_ARGLYSex equation: arg-L[e] + lys-L[c] --> arg-L[c] + lys-L[e]
reactant: 671227
reactant: 671239
product: 671251
product: 671263
is: ENSECAG00000023260.1
name: Arginine/Lysine exchanger (Arg in)
reversible: false

671227
type: SpeciesReference
stoichiometry: 1.0
species: 603662

671239
type: SpeciesReference
stoichiometry: 1.0
species: 590559

671251
type: SpeciesReference
stoichiometry: 1.0
species: 603674

671263
type: SpeciesReference
stoichiometry: 1.0
species: 590547

593451
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: CTP_C9H12N3O14P3

586616
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _4-Pyridoxate_C8H9NO4

600322
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: heparan sulfate, degradation product 14_C57H84N3O62S5

016381
type: Reaction
is: http://identifiers.org/ec-code/2.7.1.23
product: 687138
reactant: 687126
reversible: false
fast: false
product: 687150
is: ENSECAG00000022883.1
name: NAD kinase
product: 687162
notes: R_NADK subsystem: NAD Metabolism R_NADK equation: [c] : atp + nad --> adp + h + nadp
reactant: 687114

687138
type: SpeciesReference
stoichiometry: 1.0
species: 589206

687126
type: SpeciesReference
stoichiometry: 1.0
species: 590727

687150
type: SpeciesReference
stoichiometry: 1.0
species: 605370

687162
type: SpeciesReference
stoichiometry: 1.0
species: 599531

687114
type: SpeciesReference
stoichiometry: 1.0
species: 605248

012439
type: Reaction
is: ENSECAG00000024943.1
product: 647330
is: ENSECAG00000017217.1
is: ENSECAG00000008422.1
reactant: 647306
is: ENSECAG00000013368.1
notes: R_H2CO3D subsystem: Miscellaneous R_H2CO3D equation: [c] : co2 + h2o <==> h2co3
is: http://identifiers.org/ec-code/4.2.1.1
fast: false
name: carboxylic acid dissociation
is: ENSECAG00000002916.1
is: ENSECAG00000009144.1
is: ENSECAG00000010059.1
reactant: 647318
reversible: true

647330
type: SpeciesReference
stoichiometry: 1.0
species: 599325

647306
type: SpeciesReference
stoichiometry: 1.0
species: 592269

647318
type: SpeciesReference
stoichiometry: 1.0
species: 599421

598289
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: L-Glutamate_C5H8NO4

589615
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: _2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate_C9H12N5O13P3

590775
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: ATP_C10H12N5O13P3

014671
type: Reaction
is: http://identifiers.org/ec-code/1.1.1.105
modifier: 668846
reactant: 668676
product: 668736
reactant: 668688
is: ENSECAG00000014033.1
reactant: 668664
modifier: 668748
product: 668724
modifier: 668834
modifier: 668785
reversible: false
modifier: 668821
product: 668712
fast: false
product: 668700
reactant: 668652
modifier: 668809
modifier: 668797
modifier: 668773
modifier: 668760
is: http://identifiers.org/ec-code/3.1.3.5
notes: R_RDH2a subsystem: Vitamin A Metabolism R_RDH2a equation: [c] : nadp + retinol-9-cis <==> h + nadph + retinal-cis-9 R_RDH3a subsystem: Vitamin A Metabolism R_RDH3a equation: [c] : nadp + retinol-cis-11 <==> h + nadph + retinal-11-cis R_RDH1a subsystem: Vitamin A Metabolism R_RDH1a equation: [c] : nadp + retinol <==> h + nadph + retinal R_NTD11 subsystem: Purine Catabolism R_NTD11 equation: [c] : h2o + imp --> ins + pi R_NTD3 subsystem: Pyrimidine Catabolism R_NTD3 equation: [c] : dcmp + h2o --> dcyt + pi R_NTD7 subsystem: Nucleotides R_NTD7 equation: [c] : amp + h2o --> adn + pi

668676
type: SpeciesReference
stoichiometry: 1.0
species: 590041

668736
type: SpeciesReference
stoichiometry: 1.0
species: 594032

594032
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Deoxycytidine_C9H13N3O4

668688
type: SpeciesReference
stoichiometry: 1.0
species: 593887

668664
type: SpeciesReference
stoichiometry: 3.0
species: 599421

668724
type: SpeciesReference
stoichiometry: 1.0
species: 601190

608799
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: cis-11-retinal_C20H28O

608859
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: cis-11-retinol_C20H30O

668712
type: SpeciesReference
stoichiometry: 1.0
species: 589146

668700
type: SpeciesReference
stoichiometry: 3.0
species: 607462

668652
type: SpeciesReference
stoichiometry: 1.0
species: 601117

601117
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: IMP_C10H11N4O8P

010158
type: Reaction
reactant: 627330
reactant: 627342
product: 627378
reactant: 627354
fast: false
is: ENSECAG00000013708.1
is: ENSECAG00000019334.1
name: Na+/Ca2+-K+ exchange
notes: R_NCKt subsystem: Transport, Extracellular R_NCKt equation: ca2[e] + k[e] + (4) na1[c] <==> ca2[c] + k[c] + (4) na1[e]
reversible: true
product: 627366
product: 627390

627330
type: SpeciesReference
stoichiometry: 1.0
species: 591295

627342
type: SpeciesReference
stoichiometry: 1.0
species: 601359

627378
type: SpeciesReference
stoichiometry: 1.0
species: 601347

627354
type: SpeciesReference
stoichiometry: 4.0
species: 605187

627366
type: SpeciesReference
stoichiometry: 1.0
species: 591283

627390
type: SpeciesReference
stoichiometry: 4.0
species: 605200

601129
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: IMP_C10H11N4O8P

588396
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Acetaldehyde_C2H4O

598374
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO

606275
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Octadecynoyl-ACP (n-C18:2ACP)_C29H51N2O8PRS

585549
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-3-Amino-isobutanoate_C4H9NO2

017745
type: Reaction
product: 699252
reactant: 699216
reactant: 699191
is: http://identifiers.org/ec-code/2.6.1.44
product: 699228
is: ENSECAG00000008006.1
reversible: false
product: 699264
reactant: 699179
fast: false
reactant: 699203
product: 699240
notes: R_SPTix subsystem: Glycine, Serine, and Threonine Metabolism R_SPTix equation: [x] : pyr + ser-L --> ala-L + hpyr R_AGTix subsystem: Alanine and Aspartate Metabolism R_AGTix equation: [x] : ala-L + glx --> gly + pyr

699252
type: SpeciesReference
stoichiometry: 1.0
species: 598494

699216
type: SpeciesReference
stoichiometry: 1.0
species: 608677

699191
type: SpeciesReference
stoichiometry: 1.0
species: 598434

598434
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Glyoxylate_C2H1O3

699228
type: SpeciesReference
stoichiometry: 1.0
species: 600261

600261
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Hydroxypyruvate_C3H3O4

699264
type: SpeciesReference
stoichiometry: 1.0
species: 608677

699179
type: SpeciesReference
stoichiometry: 1.0
species: 589884

699203
type: SpeciesReference
stoichiometry: 1.0
species: 609388

609388
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: L-Serine_C3H7NO3

699240
type: SpeciesReference
stoichiometry: 1.0
species: 589884

599276
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: GTP_C10H12N5O14P3

604766
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _1D-myo-Inositol 1,4-bisphosphate_C6H10O12P2

593028
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: chondroitin sulfate C (GalNAc6S-GlcA), precursor 2_C37H54NO37S2X

588977
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377

595582
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: dUMP_C9H11N2O8P

013247
type: Reaction
product: 654209
reactant: 654185
notes: R_FUCASEly subsystem: N-Glycan Degradation R_FUCASEly equation: [l] : h2o + s2l2fn2m2masn --> fuc-L + s2l2n2m2masn R_FUCASE2ly subsystem: Keratan sulfate degradation R_FUCASE2ly equation: [l] : h2o + ksi --> fuc-L + ksi_deg1
reactant: 654173
product: 654233
is: ENSECAG00000024652.1
fast: false
reactant: 654197
product: 654221
is: http://identifiers.org/ec-code/3.2.1.51
reversible: false

654209
type: SpeciesReference
stoichiometry: 1.0
species: 609052

654185
type: SpeciesReference
stoichiometry: 2.0
species: 599457

654173
type: SpeciesReference
stoichiometry: 1.0
species: 601926

601926
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I_C247H393N17O213S12X

654233
type: SpeciesReference
stoichiometry: 1.0
species: 601527

654197
type: SpeciesReference
stoichiometry: 1.0
species: 609004

609004
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: PA6_C90H145N6O65X

654221
type: SpeciesReference
stoichiometry: 2.0
species: 596865

596865
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: L-Fucose_C6H12O5

601214
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Inosine_C10H12N4O5

009623
type: Reaction
fast: false
product: 622180
reactant: 622144
reactant: 622132
notes: R_ENGASE2 subsystem: N-Glycan Degradation R_ENGASE2 equation: [c] : h2o + n2m2nm --> acgam + n2m2nmn R_ENGASE subsystem: N-Glycan Degradation R_ENGASE equation: [c] : h2o + s2l2n2m2m --> acgam + s2l2n2m2mn
reversible: false
product: 622192
product: 622168
is: ENSECAG00000019553.1
is: http://identifiers.org/ec-code/3.2.1.96
reactant: 622156

622180
type: SpeciesReference
stoichiometry: 1.0
species: 605115

605115
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: reducing GlcNAc removed form of n2m2nmasn (w/o peptide)_C50H84N4O36

622144
type: SpeciesReference
stoichiometry: 1.0
species: 605067

605067
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: n2m2nmasn (w/o peptide linkage)_C58H97N5O41

622132
type: SpeciesReference
stoichiometry: 1.0
species: 609016

609016
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: de-Fuc form of PA6 (w/o peptide linkage)_C84H136N6O62

622192
type: SpeciesReference
stoichiometry: 1.0
species: 609064

609064
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: de-Fuc, reducing GlcNAc removed form of PA6 (w/o peptide linkage)_C76H123N5O57

622168
type: SpeciesReference
stoichiometry: 2.0
species: 588687

622156
type: SpeciesReference
stoichiometry: 2.0
species: 599421

015487
type: Reaction
is: ENSECAG00000021782.1
notes: R_DCK1n subsystem: Nucleotides R_DCK1n equation: [n] : atp + dcyt <==> adp + dcmp + h R_DCK2n subsystem: Nucleotides R_DCK2n equation: [n] : dcyt + utp <==> dcmp + h + udp
fast: false
product: 676588
reactant: 676552
product: 676564
product: 676576
product: 676600
reversible: true
is: http://identifiers.org/ec-code/2.7.1.74
reactant: 676528
reactant: 676540

676588
type: SpeciesReference
stoichiometry: 1.0
species: 589242

676552
type: SpeciesReference
stoichiometry: 1.0
species: 590763

590763
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: ATP_C10H12N5O13P3

676564
type: SpeciesReference
stoichiometry: 2.0
species: 599593

676576
type: SpeciesReference
stoichiometry: 1.0
species: 611453

611453
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: UDP_C9H11N2O12P2

676600
type: SpeciesReference
stoichiometry: 2.0
species: 593912

593912
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: dCMP_C9H12N3O7P

676528
type: SpeciesReference
stoichiometry: 2.0
species: 594056

594056
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: Deoxycytidine_C9H13N3O4

676540
type: SpeciesReference
stoichiometry: 1.0
species: 611938

604487
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Metanephrine_C10H16NO3

584521
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _10-formyltetrahydrofolate-[Glu](6)_C45H51N12O22

013260
type: Reaction
notes: R_FACOAL40im subsystem: Fatty acid activation R_FACOAL40im equation: [m] : atp + but + coa --> amp + btcoa + ppi
is: ENSECAG00000021788.1
fast: false
is: ENSECAG00000017507.1
product: 654281
product: 654305
reactant: 654245
product: 654293
reactant: 654269
is: http://identifiers.org/ec-code/6.2.1.2
reactant: 654257
name: fatty-acid--CoA ligase (butanoate), mitochondrial
is: ENSECAG00000021463.1
reversible: false

654281
type: SpeciesReference
stoichiometry: 1.0
species: 590089

590089
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: AMP_C10H12N5O7P

654305
type: SpeciesReference
stoichiometry: 1.0
species: 607740

654245
type: SpeciesReference
stoichiometry: 1.0
species: 591174

591174
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Butyrate (n-C4:0)_C4H7O2

654293
type: SpeciesReference
stoichiometry: 1.0
species: 591088

654269
type: SpeciesReference
stoichiometry: 1.0
species: 590751

654257
type: SpeciesReference
stoichiometry: 1.0
species: 592378

009077
type: Reaction
product: 617230
reversible: false
is: ENSECAG00000022838.1
notes: R_OCBTm subsystem: Urea cycle/amino group metabolism R_OCBTm equation: [m] : cbp + orn --> citr-L + h + pi
product: 617242
is: http://identifiers.org/ec-code/2.1.3.3
product: 617254
reactant: 617218
fast: false
reactant: 617206
name: ornithine carbamoyltransferase, irreversible

617230
type: SpeciesReference
stoichiometry: 1.0
species: 607510

617242
type: SpeciesReference
stoichiometry: 1.0
species: 592015

592015
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Citrulline_C6H13N3O3

617254
type: SpeciesReference
stoichiometry: 1.0
species: 599581

617218
type: SpeciesReference
stoichiometry: 1.0
species: 591459

591459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Carbamoyl phosphate_CH2NO5P

617206
type: SpeciesReference
stoichiometry: 1.0
species: 606491

606491
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Ornithine_C5H13N2O2

601020
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: IDP_C10H11N4O11P2

011823
type: Reaction
product: 641681
reactant: 641657
fast: false
product: 641669
notes: R_UDPGLCtg subsystem: Transport, Golgi Apparatus R_UDPGLCtg equation: udpg[c] + ump[g] <==> udpg[g] + ump[c]
reactant: 641645
name: UDP-Glc Golgi transport via CMP antiport
is: ENSECAG00000008568.1
reversible: true

641681
type: SpeciesReference
stoichiometry: 1.0
species: 611537

641657
type: SpeciesReference
stoichiometry: 1.0
species: 611684

641669
type: SpeciesReference
stoichiometry: 1.0
species: 611660

641645
type: SpeciesReference
stoichiometry: 1.0
species: 611525

593717
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2

592908
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), free chain_C45H66N2O49S4

587441
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: heptaglutamyl folate (DHF)_C49H55N13O24

601154
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Indole-3-acetate_C10H8NO2

592330
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Carbon monoxide_CO

608652
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Pyruvate_C3H3O3

603312
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Lipoate_C8H14O2S2

606191
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Octanoyl-CoA (n-C8:0CoA)_C29H46N7O17P3S

607486
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Phosphate_HO4P

605224
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Sodium_Na

597493
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: I-antigen_C72H125N4O42FULLRCO

584485
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _10-formyltetrahydrofolate-[Glu](6)_C45H51N12O22

017096
type: Reaction
reversible: false
name: Melatonin:NADP oxidoreductase
product: 692640
fast: false
reactant: 692580
product: 692652
reactant: 692604
is: http://identifiers.org/ec-code/1.14.14.1
reactant: 692592
is: ENSECAG00000008153.1
notes: R_MELATNOX subsystem: Tryptophan metabolism R_MELATNOX equation: [c] : h + melatn + nadph + o2 --> 6hoxmelatn + h2o + nadp
reactant: 692616
product: 692628
is: ENSECAG00000013817.1

692640
type: SpeciesReference
stoichiometry: 1.0
species: 605370

692580
type: SpeciesReference
stoichiometry: 1.0
species: 604403

692652
type: SpeciesReference
stoichiometry: 1.0
species: 599421

692604
type: SpeciesReference
stoichiometry: 1.0
species: 599531

692592
type: SpeciesReference
stoichiometry: 1.0
species: 605960

692616
type: SpeciesReference
stoichiometry: 1.0
species: 605442

692628
type: SpeciesReference
stoichiometry: 1.0
species: 587248

587248
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _6-Hydroxymelatonin_C13H16N2O3

013526
type: Reaction
reactant: 658972
product: 659092
is: http://identifiers.org/ec-code/1.5.1.10
product: 659104
reactant: 658984
is: ENSECAG00000021479.1
product: 659068
product: 659116
notes: R_SACCD3m subsystem: Lysine Metabolism R_SACCD3m equation: [m] : akg + h + lys-L + nadph --> h2o + nadp + saccrp-L R_SACCD4m subsystem: Lysine Metabolism R_SACCD4m equation: [m] : h2o + nadp + saccrp-L --> L2aadp6sa + glu-L + h + nadph
reactant: 658960
product: 659044
reactant: 659032
reactant: 659008
reactant: 658996
is: http://identifiers.org/ec-code/1.5.1.8
fast: false
product: 659080
product: 659056
reactant: 659020
reversible: false

658972
type: SpeciesReference
stoichiometry: 1.0
species: 609124

609124
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Saccharopine_C11H19N2O6

659092
type: SpeciesReference
stoichiometry: 1.0
species: 605394

659104
type: SpeciesReference
stoichiometry: 1.0
species: 605454

658984
type: SpeciesReference
stoichiometry: 1.0
species: 603686

603686
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Lysine_C6H15N2O2

659068
type: SpeciesReference
stoichiometry: 1.0
species: 587550

587550
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-2-Aminoadipate 6-semialdehyde_C6H11NO3

659116
type: SpeciesReference
stoichiometry: 1.0
species: 599581

658960
type: SpeciesReference
stoichiometry: 1.0
species: 599469

659044
type: SpeciesReference
stoichiometry: 1.0
species: 599469

659032
type: SpeciesReference
stoichiometry: 1.0
species: 599581

659008
type: SpeciesReference
stoichiometry: 1.0
species: 605394

658996
type: SpeciesReference
stoichiometry: 1.0
species: 589712

659080
type: SpeciesReference
stoichiometry: 1.0
species: 598301

659056
type: SpeciesReference
stoichiometry: 1.0
species: 609124

659020
type: SpeciesReference
stoichiometry: 1.0
species: 605454

586884
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: (R)-5-Diphosphomevalonate_C6H10O10P2

012125
type: Reaction
product: 644034
notes: R_SELCYSTS subsystem: Selenoamino acid metabolism R_SELCYSTS equation: [c] : selhcys + ser-L --> h2o + selcyst R_CYSTS subsystem: Methionine Metabolism R_CYSTS equation: [c] : hcys-L + ser-L --> cyst-L + h2o
fast: false
is: ENSECAG00000022794.1
is: http://identifiers.org/ec-code/4.2.1.22
product: 644008
reversible: false
reactant: 643995
reactant: 643971
reactant: 643983
is: ENSECAG00000021749.1
product: 644021

644034
type: SpeciesReference
stoichiometry: 2.0
species: 599421

644008
type: SpeciesReference
stoichiometry: 1.0
species: 593548

593548
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Cystathionine_C7H14N2O4S

643995
type: SpeciesReference
stoichiometry: 1.0
species: 609280

643971
type: SpeciesReference
stoichiometry: 1.0
species: 599737

599737
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Homocysteine_C4H9NO2S

643983
type: SpeciesReference
stoichiometry: 2.0
species: 609352

644021
type: SpeciesReference
stoichiometry: 1.0
species: 609268

609268
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Selenocystathionine_C7H14N2O4Se

589543
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Etiocholan-3alpha-ol-17-one 3-glucuronide_C25H38O8

009221
type: Reaction
is: ENSECAG00000005185.1
is: ENSECAG00000016916.1
reactant: 618780
notes: R_DAGK_hs subsystem: Glycerophospholipid Metabolism R_DAGK_hs equation: [c] : atp + dag_hs <==> adp + h + pa_hs
fast: false
product: 618804
is: ENSECAG00000011968.1
product: 618817
reactant: 618768
is: http://identifiers.org/ec-code/2.7.1.107
name: Diacylglycerol phosphate kinase (homo sapiens)
is: ENSECAG00000000237.1
product: 618792
is: ENSECAG00000022309.1
is: ENSECAG00000021851.1
is: ENSECAG00000019230.1
reversible: true

618780
type: SpeciesReference
stoichiometry: 1.0
species: 590727

618804
type: SpeciesReference
stoichiometry: 1.0
species: 599531

618817
type: SpeciesReference
stoichiometry: 1.0
species: 606564

618768
type: SpeciesReference
stoichiometry: 1.0
species: 593692

618792
type: SpeciesReference
stoichiometry: 1.0
species: 589206

010604
type: Reaction
fast: false
reactant: 631365
product: 631413
is: ENSECAG00000020924.1
reversible: false
is: http://identifiers.org/ec-code/3.1.1.4
notes: R_PLA2_2 subsystem: Glycerophospholipid Metabolism R_PLA2_2 equation: [c] : h2o + pchol_hs --> Rtotal2 + h + lpchol_hs
reactant: 631377
product: 631401
name: phospholipase A2
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is: ENSECAG00000014501.1
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notes: R_PYK subsystem: Glycolysis/Gluconeogenesis R_PYK equation: [c] : adp + h + pep --> atp + pyr
reversible: false
is: http://identifiers.org/ec-code/2.7.1.40
is: ENSECAG00000007644.1
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017397
type: Reaction
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product: 696312
product: 696252
reactant: 695652
reactant: 695700
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reactant: 695904
reactant: 695844
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product: 696168
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reactant: 695688
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reactant: 696012
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reactant: 695748
reactant: 695988
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reactant: 695976
reactant: 695724
reactant: 695832
reactant: 695760
reactant: 695604
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reactant: 695892
reactant: 695664
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reactant: 695952
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product: 696264
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product: 696096
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reactant: 695916
reactant: 696000
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species: 611417

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species: 588772

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species: 588735

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species: 602118

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species: 597468

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species: 602336

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species: 599445

696048
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species: 597578

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type: Species
constant: false
boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Gal-Gal-Gal-Gal-Gal-Glc-Cer (homo sapiens)_C54H96NO32FULLRCO

695748
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species: 611381

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species: 602323

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species: 597686

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type: Species
constant: false
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name: Gal-Gal-Gal-Glc-Cer (homo sapiens)_C42H76NO22FULLRCO

696384
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species: 597481

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name: i-antigen_C58H102N3O32FULLRCO

695784
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species: 597747

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species: 594758

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name: Digalactosylceramide_C30H56NO12FULLRCO

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species: 588760

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species: 597384

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695976
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species: 597686

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species: 588603

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species: 597650

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696288
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species: 598784

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696084
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696000
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species: 588578

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type: Species
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name: N-Acetyl-D-galactosamine_C8H15NO6

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species: 597456

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013827
type: Reaction
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is: http://identifiers.org/ec-code/2.7.7.10
notes: R_GALT subsystem: Galactose metabolism R_GALT equation: [c] : gal1p + h + utp <==> ppi + udpgal R_UGLT subsystem: Galactose metabolism R_UGLT equation: [c] : gal1p + udpg <==> g1p + udpgal
is: http://identifiers.org/ec-code/2.7.7.12
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is: ENSECAG00000008176.1

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species: 611525

661341
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species: 611562

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species: 611901

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586832
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name: monoacylglycerol 2 (homo sapiens)_C3H7O2FULLR2CO2

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name: _10-Formyltetrahydrofolate_C20H21N7O7

016693
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product: 689600
is: ENSECAG00000019885.1
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name: Na+/K+ exchanging ATPase
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is: ENSECAG00000013702.1
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is: ENSECAG00000017771.1
reversible: false
fast: false
reactant: 689540
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notes: R_NaKt subsystem: Transport, Extracellular R_NaKt equation: atp[c] + h2o[c] + (2) k[e] + (3) na1[c] --> adp[c] + h[c] + (2) k[c] + (3) na1[e] + pi[c]
product: 689564
is: http://identifiers.org/ec-code/3.6.3.9
reactant: 689528
is: ENSECAG00000024827.1
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is: ENSECAG00000024542.1

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species: 599531

689600
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species: 589206

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species: 599421

689588
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species: 605200

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species: 605187

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species: 601359

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species: 601347

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species: 590727

689576
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species: 607462

010713
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reactant: 632512
reactant: 632500
is: ENSECAG00000019442.1
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product: 632560
product: 632584
reactant: 632452
reactant: 632464
reactant: 632524
reactant: 632488
reactant: 632476
product: 632548
fast: false
notes: R_P4501B1r subsystem: Steroid Metabolism R_P4501B1r equation: [r] : estradiol + h + nadph + o2 --> h2o + hestratriol + nadp R_MELATNOX subsystem: Tryptophan metabolism R_MELATNOX equation: [c] : h + melatn + nadph + o2 --> 6hoxmelatn + h2o + nadp
is: http://identifiers.org/ec-code/1.14.14.1
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632560
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species: 599929

599929
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _4,17 dihydroxy estradiol_C18H24O3

632609
type: SpeciesReference
stoichiometry: 1.0
species: 599421

632597
type: SpeciesReference
stoichiometry: 1.0
species: 605418

594636
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: _7,8-Dihydrofolate_C19H19N7O6

590739
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: ATP_C10H12N5O13P3

602952
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: D-Lactaldehyde_C3H6O2

597095
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: fucosyl galactosylgloboside (homo sapiens)_C56H99N2O31FULLRCO

019441
type: Reaction
fast: false
reactant: 716225
name: argininosuccinate lyase
is: http://identifiers.org/ec-code/4.3.2.1
product: 716249
reversible: true
is: ENSECAG00000012930.1
product: 716237
notes: R_ARGSL subsystem: Alanine and Aspartate Metabolism R_ARGSL equation: [c] : argsuc <==> arg-L + fum

716225
type: SpeciesReference
stoichiometry: 1.0
species: 590583

590583
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N(omega)-(L-Arginino)succinate_C10H17N4O6

716249
type: SpeciesReference
stoichiometry: 1.0
species: 590547

716237
type: SpeciesReference
stoichiometry: 1.0
species: 597107

597107
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Fumarate_C4H2O4

016407
type: Reaction
name: _3-hydroxyanthranilate 3,4-dioxygenase
reactant: 687235
product: 687271
is: http://identifiers.org/ec-code/1.13.11.6
reactant: 687247
product: 687259
notes: R_3HAO subsystem: Tryptophan metabolism R_3HAO equation: [c] : 3hanthrn + o2 --> cmusa + h
fast: false
reversible: false
is: ENSECAG00000017940.1

687235
type: SpeciesReference
stoichiometry: 1.0
species: 585646

585646
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Hydroxyanthranilate_C7H7NO3

687271
type: SpeciesReference
stoichiometry: 1.0
species: 599531

687247
type: SpeciesReference
stoichiometry: 1.0
species: 605960

687259
type: SpeciesReference
stoichiometry: 1.0
species: 592257

592257
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _2-Amino-3-carboxymuconate semialdehyde_C7H6NO5

594721
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: dIDP_C10H11N4O10P2

589519
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Etiocholan-3alpha-ol-17-one 3-glucuronide_C25H38O8

016234
type: Reaction
product: 686170
reactant: 686134
is: ENSECAG00000006878.1
is: http://identifiers.org/ec-code/4.1.1.15
fast: false
notes: R_3SALACBOXL subsystem: Taurine and hypotaurine metabolism R_3SALACBOXL equation: [c] : 3sala + h --> co2 + hyptaur R_LCYSTCBOXL subsystem: Taurine and hypotaurine metabolism R_LCYSTCBOXL equation: [c] : Lcyst + h --> co2 + taur
reversible: false
product: 686158
is: ENSECAG00000009017.1
reactant: 686110
reactant: 686122
product: 686146

686170
type: SpeciesReference
stoichiometry: 2.0
species: 592269

686134
type: SpeciesReference
stoichiometry: 2.0
species: 599531

686158
type: SpeciesReference
stoichiometry: 1.0
species: 600852

686110
type: SpeciesReference
stoichiometry: 1.0
species: 587599

686122
type: SpeciesReference
stoichiometry: 1.0
species: 586082

686146
type: SpeciesReference
stoichiometry: 1.0
species: 610067

597180
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: alpha-D-Glucosyl-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1840H3028N20O670P20

587417
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: heptaglutamyl folate (DHF)_C49H55N13O24

593378
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: chondroitin sulfate A (GalNAc4S-GlcA) proteoglycan_C45H66N2O45S3X

594288
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: dGMP_C10H12N5O7P

017937
type: Reaction
notes: R_SBTD_D2 subsystem: Fructose and Mannose Metabolism R_SBTD_D2 equation: [c] : nad + sbt-D --> fru + h + nadh
reversible: false
name: D-sorbitol dehydrogenase (D-fructose producing)
product: 700732
reactant: 700708
is: http://identifiers.org/ec-code/1.1.1.14
product: 700756
product: 700744
is: ENSECAG00000005266.1
reactant: 700720
fast: false

700732
type: SpeciesReference
stoichiometry: 1.0
species: 596756

596756
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Fructose_C6H12O6

700708
type: SpeciesReference
stoichiometry: 1.0
species: 605248

700756
type: SpeciesReference
stoichiometry: 1.0
species: 605322

700744
type: SpeciesReference
stoichiometry: 1.0
species: 599531

700720
type: SpeciesReference
stoichiometry: 1.0
species: 609172

611733
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: UMP_C9H11N2O9P

008969
type: Reaction
product: 616455
reactant: 616370
reversible: true
reactant: 616430
reactant: 616418
product: 616443
product: 616503
reactant: 616382
product: 616479
is: http://identifiers.org/ec-code/6.2.1.4
fast: false
notes: R_SUCOASm subsystem: Citric Acid Cycle R_SUCOASm equation: [m] : atp + coa + succ <==> adp + pi + succoa R_SUCOAS1m subsystem: Citric Acid Cycle R_SUCOAS1m equation: [m] : coa + gtp + succ <==> gdp + pi + succoa R_MECOAS1m subsystem: C5-Branched dibasic acid metabolism R_MECOAS1m equation: [m] : coa + gtp + mescon <==> gdp + mescoa + pi R_MECOALm subsystem: C5-Branched dibasic acid metabolism R_MECOALm equation: [m] : atp + coa + mescon <==> adp + mescoa + pi R_ITCOALm subsystem: C5-Branched dibasic acid metabolism R_ITCOALm equation: [m] : atp + coa + itacon <==> adp + itaccoa + pi R_ITCOAL1m subsystem: C5-Branched dibasic acid metabolism R_ITCOAL1m equation: [m] : coa + gtp + itacon <==> gdp + itaccoa + pi
product: 616491
reactant: 616406
is: http://identifiers.org/ec-code/6.2.1.5
is: ENSECAG00000012979.1
product: 616467
reactant: 616394

616455
type: SpeciesReference
stoichiometry: 2.0
species: 609957

616370
type: SpeciesReference
stoichiometry: 2.0
species: 604547

616430
type: SpeciesReference
stoichiometry: 2.0
species: 609921

616418
type: SpeciesReference
stoichiometry: 2.0
species: 601287

601287
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Itaconate_C5H4O4

616443
type: SpeciesReference
stoichiometry: 2.0
species: 601275

601275
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Itaconyl-CoA_C26H35N7O19P3S

616503
type: SpeciesReference
stoichiometry: 3.0
species: 597976

597976
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: GDP_C10H12N5O11P2

616382
type: SpeciesReference
stoichiometry: 6.0
species: 592378

616479
type: SpeciesReference
stoichiometry: 6.0
species: 607510

616491
type: SpeciesReference
stoichiometry: 3.0
species: 589230

616406
type: SpeciesReference
stoichiometry: 3.0
species: 599264

599264
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: GTP_C10H12N5O14P3

616467
type: SpeciesReference
stoichiometry: 2.0
species: 604535

604535
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Mesaconyl-CoA_C26H35N7O19P3S

616394
type: SpeciesReference
stoichiometry: 3.0
species: 590751

011486
type: Reaction
reactant: 638478
reactant: 638405
reactant: 638429
product: 638526
reversible: false
reactant: 638417
reactant: 638490
product: 638575
product: 638538
is: ENSECAG00000003387.1
product: 638587
fast: false
reactant: 638466
notes: R_BTND1 subsystem: Biotin Metabolism R_BTND1 equation: [c] : biocyt + h2o --> btn + lys-L R_BTND1n subsystem: Biotin Metabolism R_BTND1n equation: [n] : biocyt + h2o --> btn + lys-L R_BTNDe subsystem: Biotin Metabolism R_BTNDe equation: [e] : biocyt + h2o --> btn + lys-L R_BTNDm subsystem: Biotin Metabolism R_BTNDm equation: [m] : biocyt + h2o --> btn + lys-L
product: 638550
reactant: 638441
product: 638563
is: http://identifiers.org/ec-code/3.5.1.12
product: 638502
reactant: 638453
product: 638514

638478
type: SpeciesReference
stoichiometry: 1.0
species: 591040

591040
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Biocytin_C16H28N4O4S

638405
type: SpeciesReference
stoichiometry: 1.0
species: 599469

638429
type: SpeciesReference
stoichiometry: 1.0
species: 599433

638526
type: SpeciesReference
stoichiometry: 1.0
species: 591125

638417
type: SpeciesReference
stoichiometry: 1.0
species: 591052

638490
type: SpeciesReference
stoichiometry: 1.0
species: 591028

591028
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Biocytin_C16H28N4O4S

638575
type: SpeciesReference
stoichiometry: 1.0
species: 591137

591137
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: Biotin_C10H15N2O3S

638538
type: SpeciesReference
stoichiometry: 1.0
species: 591101

591101
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Biotin_C10H15N2O3S

638587
type: SpeciesReference
stoichiometry: 1.0
species: 603698

638466
type: SpeciesReference
stoichiometry: 1.0
species: 599481

638550
type: SpeciesReference
stoichiometry: 1.0
species: 603686

638441
type: SpeciesReference
stoichiometry: 1.0
species: 591016

591016
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Biocytin_C16H28N4O4S

638563
type: SpeciesReference
stoichiometry: 1.0
species: 603674

638502
type: SpeciesReference
stoichiometry: 1.0
species: 603662

638453
type: SpeciesReference
stoichiometry: 1.0
species: 599421

638514
type: SpeciesReference
stoichiometry: 1.0
species: 591113

606855
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: phosphatidylinositol (homo sapiens)_C9H16O9PFULLRCO2FULLR2CO2

591797
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425

017637
type: Reaction
fast: false
reversible: false
product: 698443
notes: R_CAMPt subsystem: Transport, Extracellular R_CAMPt equation: atp[c] + camp[c] + h2o[c] --> adp[c] + camp[e] + h[c] + pi[c] R_CGMPt subsystem: Transport, Extracellular R_CGMPt equation: _35cgmp[c] + atp[c] + h2o[c] --> 35cgmp[e] + adp[c] + h[c] + pi[c]
reactant: 698369
is: ENSECAG00000007961.1
product: 698393
product: 698431
reactant: 698357
product: 698405
product: 698418
reactant: 698381
reactant: 698345

698443
type: SpeciesReference
stoichiometry: 1.0
species: 585488

585488
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: _3',5'-Cyclic GMP_C10H11N5O7P

698369
type: SpeciesReference
stoichiometry: 1.0
species: 585476

698393
type: SpeciesReference
stoichiometry: 2.0
species: 607462

698431
type: SpeciesReference
stoichiometry: 2.0
species: 599531

698357
type: SpeciesReference
stoichiometry: 2.0
species: 590727

698405
type: SpeciesReference
stoichiometry: 1.0
species: 591333

698418
type: SpeciesReference
stoichiometry: 2.0
species: 589206

698381
type: SpeciesReference
stoichiometry: 2.0
species: 599421

698345
type: SpeciesReference
stoichiometry: 1.0
species: 591320

604025
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: (alpha-D-Mannosyl)7-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1720H2828N20O570P20

590223
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: P1,P4-Bis(5'-adenosyl) tetraphosphate_C20H24N10O19P4

606058
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Superoxide anion_O2

595486
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dithiothreitol_C4H10O2S2

603650
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Gal-Xyl-L-Ser (protein)_C11H19O9X

606989
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

015883
type: Reaction
reactant: 682097
product: 682157
product: 682193
notes: R_CAMPt subsystem: Transport, Extracellular R_CAMPt equation: atp[c] + camp[c] + h2o[c] --> adp[c] + camp[e] + h[c] + pi[c] R_PROSTGE2t3 subsystem: Transport, Extracellular R_PROSTGE2t3 equation: atp[c] + h2o[c] + prostge2[c] --> adp[c] + h[c] + pi[c] + prostge2[e] R_ESTRADIOLGLCt2 subsystem: Transport, Extracellular R_ESTRADIOLGLCt2 equation: atp[c] + estradiolglc[c] + h2o[c] --> adp[c] + estradiolglc[e] + h[c] + pi[c] R_CGMPt subsystem: Transport, Extracellular R_CGMPt equation: _35cgmp[c] + atp[c] + h2o[c] --> 35cgmp[e] + adp[c] + h[c] + pi[c] R_PROSTGE1t3 subsystem: Transport, Extracellular R_PROSTGE1t3 equation: atp[c] + h2o[c] + prostge1[c] --> adp[c] + h[c] + pi[c] + prostge1[e]
product: 682181
reactant: 682036
reactant: 682048
reactant: 682109
is: ENSECAG00000017168.1
product: 682205
product: 682121
reactant: 682073
reversible: false
product: 682145
fast: false
product: 682169
reactant: 682085
product: 682133
reactant: 682060

682097
type: SpeciesReference
stoichiometry: 1.0
species: 585476

682157
type: SpeciesReference
stoichiometry: 5.0
species: 589206

682193
type: SpeciesReference
stoichiometry: 5.0
species: 599531

682181
type: SpeciesReference
stoichiometry: 1.0
species: 595992

682036
type: SpeciesReference
stoichiometry: 1.0
species: 608271

682048
type: SpeciesReference
stoichiometry: 1.0
species: 595980

682109
type: SpeciesReference
stoichiometry: 5.0
species: 599421

682205
type: SpeciesReference
stoichiometry: 1.0
species: 585488

682121
type: SpeciesReference
stoichiometry: 5.0
species: 607462

682073
type: SpeciesReference
stoichiometry: 5.0
species: 590727

682145
type: SpeciesReference
stoichiometry: 1.0
species: 591333

682169
type: SpeciesReference
stoichiometry: 1.0
species: 608283

682085
type: SpeciesReference
stoichiometry: 1.0
species: 608247

682133
type: SpeciesReference
stoichiometry: 1.0
species: 608259

682060
type: SpeciesReference
stoichiometry: 1.0
species: 591320

611405
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: UDP_C9H11N2O12P2

015547
type: Reaction
product: 677154
is: ENSECAG00000007009.1
is: ENSECAG00000018981.1
fast: false
reactant: 677118
product: 677142
reactant: 677130
is: ENSECAG00000014769.1
product: 677166
name: inositol-1,4,5-trisphosphate 3-kinase
notes: R_MI145PK subsystem: Inositol Phosphate Metabolism R_MI145PK equation: [c] : atp + mi145p --> adp + h + mi1345p
is: http://identifiers.org/ec-code/2.7.1.127
reversible: false

677154
type: SpeciesReference
stoichiometry: 1.0
species: 589206

677118
type: SpeciesReference
stoichiometry: 1.0
species: 590727

677142
type: SpeciesReference
stoichiometry: 1.0
species: 604682

604682
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _1D-myo-Inositol 1,3,4,5-tetrakisphosphate_C6H8O18P4

677130
type: SpeciesReference
stoichiometry: 1.0
species: 604742

604742
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _1D-myo-Inositol 1,4,5-trisphosphate_C6H9O15P3

677166
type: SpeciesReference
stoichiometry: 1.0
species: 599531

588058
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: protein-linked serine residue (glycosaminoglycan attachment site)_XH

589122
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: acyl-dihydroxyacetone phosphate_C3H4O6PFULLRCO

008800
type: Reaction
product: 614782
fast: false
name: lactoylglutathione lyase
reactant: 614770
reactant: 614758
notes: R_LGTHL subsystem: Pyruvate Metabolism R_LGTHL equation: [c] : gthrd + mthgxl --> lgt-S
is: ENSECAG00000019652.1
reversible: false
is: http://identifiers.org/ec-code/4.4.1.5

614782
type: SpeciesReference
stoichiometry: 1.0
species: 603276

614770
type: SpeciesReference
stoichiometry: 1.0
species: 605019

614758
type: SpeciesReference
stoichiometry: 1.0
species: 599192

593754
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: dAMP_C10H12N5O6P

604982
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol, human liver homolog_C1300H2128N20O220P20

016051
type: Reaction
reactant: 683392
reactant: 683537
reactant: 683428
reactant: 683477
product: 683646
is: ENSECAG00000000428.1
product: 683670
product: 683610
notes: R_CYTK5 subsystem: Nucleotides R_CYTK5 equation: [c] : ctp + dcmp <==> cdp + dcdp R_CYTK10n subsystem: Nucleotides R_CYTK10n equation: [n] : cmp + dgtp <==> cdp + dgdp R_CYTK6n subsystem: Nucleotides R_CYTK6n equation: [n] : cmp + ctp <==> (2) cdp R_CYTK6 subsystem: Nucleotides R_CYTK6 equation: [c] : cmp + ctp <==> (2) cdp R_UMPK5 subsystem: Nucleotides R_UMPK5 equation: [c] : datp + ump <==> dadp + udp R_CYTK11 subsystem: Nucleotides R_CYTK11 equation: [c] : dcmp + dgtp <==> dcdp + dgdp R_UMPK3n subsystem: Nucleotides R_UMPK3n equation: [n] : ump + utp <==> (2) udp R_UMPK6n subsystem: Nucleotides R_UMPK6n equation: [n] : dctp + ump <==> dcdp + udp R_CYTK14n subsystem: Nucleotides R_CYTK14n equation: [n] : dcmp + utp <==> dcdp + udp R_UMPK2 subsystem: Nucleotides R_UMPK2 equation: [c] : ctp + ump <==> cdp + udp R_CYTK2n subsystem: Nucleotides R_CYTK2n equation: [n] : atp + dcmp <==> adp + dcdp R_UMPK6 subsystem: Nucleotides R_UMPK6 equation: [c] : dctp + ump <==> dcdp + udp R_UMPK4 subsystem: Nucleotides R_UMPK4 equation: [c] : gtp + ump <==> gdp + udp R_CYTK2 subsystem: Nucleotides R_CYTK2 equation: [c] : atp + dcmp <==> adp + dcdp R_UMPK5n subsystem: Nucleotides R_UMPK5n equation: [n] : datp + ump <==> dadp + udp R_UMPK subsystem: Nucleotides R_UMPK equation: [c] : atp + ump <==> adp + udp R_CYTK13 subsystem: Nucleotides R_CYTK13 equation: [c] : datp + dcmp <==> dadp + dcdp R_CYTK13n subsystem: Nucleotides R_CYTK13n equation: [n] : datp + dcmp <==> dadp + dcdp R_UMPK2n subsystem: Nucleotides R_UMPK2n equation: [n] : ctp + ump <==> cdp + udp R_CYTK9n subsystem: Nucleotides R_CYTK9n equation: [n] : cmp + dctp <==> cdp + dcdp R_CYTK7n subsystem: Nucleotides R_CYTK7n equation: [n] : cmp + utp <==> cdp + udp R_CYTK7 subsystem: Nucleotides R_CYTK7 equation: [c] : cmp + utp <==> cdp + udp R_CYTK3n subsystem: Nucleotides R_CYTK3n equation: [n] : ctp + dcmp <==> cdp + dcdp R_CYTK1 subsystem: Nucleotides R_CYTK1 equation: [c] : atp + cmp <==> adp + cdp R_CYTK14 subsystem: …
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product: 683754
reactant: 683380
reactant: 683416
reactant: 683452
product: 683634
reactant: 683501
reactant: 683489
product: 683622
fast: false
reactant: 683586
product: 683730
product: 683694
reactant: 683561
reactant: 683525
reversible: true
reactant: 683598
product: 683706
reactant: 683368
reactant: 683465
product: 683682
reactant: 683440
reactant: 683404
reactant: 683513
is: http://identifiers.org/ec-code/2.7.4.14
reactant: 683549
product: 683718
reactant: 683574
product: 683658
product: 683742

683392
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species: 594372

594372
type: Species
constant: false
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has only substance units: false
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initial amount: NaN
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name: dGTP_C10H12N5O13P3

683537
type: SpeciesReference
stoichiometry: 3.0
species: 599276

683428
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species: 590727

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species: 593790

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species: 591507

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: CDP_C9H12N3O11P2

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species: 593680

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constant: false
boundary condition: false
has only substance units: false
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initial amount: NaN
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name: dADP_C10H12N5O9P2

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species: 597988

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type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: GDP_C10H12N5O11P2

683766
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species: 591483

683754
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species: 594227

683380
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species: 592196

592196
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: CMP_C9H12N3O8P

683416
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stoichiometry: 3.0
species: 593463

683452
type: SpeciesReference
stoichiometry: 3.0
species: 593766

683634
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stoichiometry: 3.0
species: 593656

683501
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stoichiometry: 3.0
species: 594348

594348
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: dGTP_C10H12N5O13P3

683489
type: SpeciesReference
stoichiometry: 1.0
species: 599240

683622
type: SpeciesReference
stoichiometry: 1.0
species: 597940

683586
type: SpeciesReference
stoichiometry: 3.0
species: 611901

683730
type: SpeciesReference
stoichiometry: 9.0
species: 593839

683694
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stoichiometry: 10.0
species: 593863

593863
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: dCDP_C9H12N3O10P2

683561
type: SpeciesReference
stoichiometry: 3.0
species: 593996

683525
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stoichiometry: 7.0
species: 611721

611721
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: UMP_C9H11N2O9P

683598
type: SpeciesReference
stoichiometry: 3.0
species: 593439

683706
type: SpeciesReference
stoichiometry: 3.0
species: 589242

683368
type: SpeciesReference
stoichiometry: 6.0
species: 592147

683465
type: SpeciesReference
stoichiometry: 3.0
species: 594020

683682
type: SpeciesReference
stoichiometry: 3.0
species: 589206

683440
type: SpeciesReference
stoichiometry: 3.0
species: 611938

683404
type: SpeciesReference
stoichiometry: 7.0
species: 611660

683513
type: SpeciesReference
stoichiometry: 3.0
species: 590763

683549
type: SpeciesReference
stoichiometry: 7.0
species: 593912

683718
type: SpeciesReference
stoichiometry: 10.0
species: 611393

683574
type: SpeciesReference
stoichiometry: 6.0
species: 593887

683658
type: SpeciesReference
stoichiometry: 10.0
species: 611453

683742
type: SpeciesReference
stoichiometry: 3.0
species: 594251

594251
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: dGDP_C10H12N5O10P2

016810
type: Reaction
product: 690249
reactant: 690201
reactant: 690225
is: ENSECAG00000014049.1
reactant: 690237
product: 690297
product: 690273
is: http://identifiers.org/ec-code/3.6.1.19
product: 690261
reversible: false
fast: false
product: 690285
notes: R_NTPP11 subsystem: Nucleotides R_NTPP11 equation: [c] : h2o + xtp --> h + ppi + xmp R_NTPP10 subsystem: Nucleotides R_NTPP10 equation: [c] : ditp + h2o --> dimp + h + ppi R_NTPP9 subsystem: Nucleotides R_NTPP9 equation: [c] : h2o + itp --> h + imp + ppi
reactant: 690213

690249
type: SpeciesReference
stoichiometry: 1.0
species: 612155

612155
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Xanthosine 5'-phosphate_C10H11N4O9P

690201
type: SpeciesReference
stoichiometry: 1.0
species: 612488

612488
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: XTP_C10H11N4O15P3

690225
type: SpeciesReference
stoichiometry: 3.0
species: 599421

690237
type: SpeciesReference
stoichiometry: 1.0
species: 601299

601299
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: ITP_C10H11N4O14P3

690297
type: SpeciesReference
stoichiometry: 3.0
species: 607728

690273
type: SpeciesReference
stoichiometry: 1.0
species: 601117

690261
type: SpeciesReference
stoichiometry: 1.0
species: 594782

594782
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: dIMP_C10H11N4O7P

690285
type: SpeciesReference
stoichiometry: 3.0
species: 599531

690213
type: SpeciesReference
stoichiometry: 1.0
species: 594820

009149
type: Reaction
product: 618140
reactant: 618103
product: 618249
is: http://identifiers.org/ec-code/2.7.1.137
product: 618200
product: 618164
reactant: 618054
reversible: false
reactant: 618078
product: 618224
product: 618212
reactant: 618128
reactant: 618090
product: 618188
product: 618236
is: ENSECAG00000015106.1
notes: R_PI4P3K subsystem: Inositol Phosphate Metabolism R_PI4P3K equation: [c] : atp + pail4p_hs --> adp + h + pail34p_hs R_PIK3er subsystem: Inositol Phosphate Metabolism R_PIK3er equation: [r] : atp + pail_hs --> adp + h + pail3p_hs R_PIK3 subsystem: Inositol Phosphate Metabolism R_PIK3 equation: [c] : atp + pail_hs --> adp + h + pail3p_hs R_PI5P3Ker subsystem: Inositol Phosphate Metabolism R_PI5P3Ker equation: [r] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI5P3K subsystem: Inositol Phosphate Metabolism R_PI5P3K equation: [c] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI4P3Ker subsystem: Inositol Phosphate Metabolism R_PI4P3Ker equation: [r] : atp + pail4p_hs --> adp + h + pail34p_hs
fast: false
product: 618176
reactant: 618066
reactant: 618116
reactant: 618042
product: 618152

618140
type: SpeciesReference
stoichiometry: 1.0
species: 606698

606698
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: phosphatidylinositol-3,4-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

618103
type: SpeciesReference
stoichiometry: 3.0
species: 590727

618249
type: SpeciesReference
stoichiometry: 3.0
species: 599531

618200
type: SpeciesReference
stoichiometry: 1.0
species: 606722

606722
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: phosphatidylinositol-3,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

618164
type: SpeciesReference
stoichiometry: 1.0
species: 606734

606734
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: phosphatidylinositol-3,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

618054
type: SpeciesReference
stoichiometry: 1.0
species: 606795

606795
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

618078
type: SpeciesReference
stoichiometry: 1.0
species: 606881

606881
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: phosphatidylinositol (homo sapiens)_C9H16O9PFULLRCO2FULLR2CO2

618224
type: SpeciesReference
stoichiometry: 1.0
species: 606758

606758
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _1-Phosphatidyl-1D-myo-inositol 3-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

618212
type: SpeciesReference
stoichiometry: 1.0
species: 606710

606710
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: phosphatidylinositol-3,4-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

618128
type: SpeciesReference
stoichiometry: 3.0
species: 590775

618090
type: SpeciesReference
stoichiometry: 1.0
species: 606843

606843
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _1-Phosphatidyl-1D-myo-inositol 5-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

618188
type: SpeciesReference
stoichiometry: 1.0
species: 606746

606746
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _1-Phosphatidyl-1D-myo-inositol 3-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

618236
type: SpeciesReference
stoichiometry: 3.0
species: 599605

618176
type: SpeciesReference
stoichiometry: 3.0
species: 589254

589254
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: ADP_C10H12N5O10P2

618066
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stoichiometry: 1.0
species: 606831

606831
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _1-Phosphatidyl-1D-myo-inositol 5-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

618116
type: SpeciesReference
stoichiometry: 1.0
species: 606819

606819
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

618042
type: SpeciesReference
stoichiometry: 1.0
species: 606855

618152
type: SpeciesReference
stoichiometry: 3.0
species: 589206

013019
type: Reaction
is: ENSECAG00000016744.1
is: ENSECAG00000014168.1
reactant: 652467
fast: false
reversible: true
product: 652479
notes: R_PGESr subsystem: Eicosanoid Metabolism R_PGESr equation: [r] : prostgh2 <==> prostge2
name: Prostaglandin E synthase
is: http://identifiers.org/ec-code/5.3.99.3

652467
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stoichiometry: 1.0
species: 608343

608343
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Prostaglandin H2_C20H31O5

652479
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stoichiometry: 1.0
species: 608295

608295
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Prostaglandin E2_C20H31O5

593427
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: chondroitin sulfate E (GalNAc4,6diS-GlcA) proteoglycan_C45H63N2O54S6X

591640
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Choline_C5H14NO

011727
type: Reaction
is: ENSECAG00000010734.1
reactant: 640791
is: ENSECAG00000024477.1
fast: false
reactant: 640815
is: ENSECAG00000023866.1
name: cytochrome p450 P450 3A7
product: 640827
is: ENSECAG00000019724.1
is: ENSECAG00000016004.1
is: ENSECAG00000008604.1
notes: R_P4503A7r subsystem: Steroid Metabolism R_P4503A7r equation: [r] : h + nadph + o2 + tststerone --> 6htststerone + h2o + nadp
reversible: false
reactant: 640779
reactant: 640803
product: 640851
is: ENSECAG00000022630.1
product: 640839

640791
type: SpeciesReference
stoichiometry: 1.0
species: 605479

640815
type: SpeciesReference
stoichiometry: 1.0
species: 599605

640827
type: SpeciesReference
stoichiometry: 1.0
species: 599493

640779
type: SpeciesReference
stoichiometry: 1.0
species: 606008

640803
type: SpeciesReference
stoichiometry: 1.0
species: 611138

640851
type: SpeciesReference
stoichiometry: 1.0
species: 587260

587260
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _6 beta hydroxy testosterone_C19H28O3

640839
type: SpeciesReference
stoichiometry: 1.0
species: 605418

598422
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Glyoxylate_C2H1O3

604838
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _1D-myo-Inositol 4-phosphate_C6H11O9P

018611
type: Reaction
product: 706657
product: 706766
is: ENSECAG00000017949.1
product: 706826
product: 706669
is: http://identifiers.org/ec-code/6.3.2.17
product: 706754
product: 706814
product: 706778
reactant: 706427
product: 706838
reactant: 706391
reactant: 706511
product: 706681
reactant: 706535
reactant: 706547
reactant: 706621
reversible: false
reactant: 706475
product: 706887
product: 706802
reactant: 706585
product: 706693
reactant: 706500
product: 706899
reactant: 706367
reactant: 706451
notes: R_FPGS subsystem: Folate Metabolism R_FPGS equation: [c] : (4) atp + (4) glu-L + thf --> 5thf + (4) adp + (4) h + (4) pi R_FPGS9 subsystem: Folate Metabolism R_FPGS9 equation: [c] : 10fthf6glu + atp + glu-L --> 10fthf7glu + adp + h + pi R_FPGS3m subsystem: Folate Metabolism R_FPGS3m equation: [m] : 6thf + atp + glu-L --> 7thf + adp + h + pi R_FPGS7 subsystem: Folate Metabolism R_FPGS7 equation: [c] : 10fthf + (4) atp + (4) glu-L --> 10fthf5glu + (4) adp + (4) h + (4) pi R_FPGSm subsystem: Folate Metabolism R_FPGSm equation: [m] : (4) atp + (4) glu-L + thf --> 5thf + (4) adp + (4) h + (4) pi R_FPGS4 subsystem: Folate Metabolism R_FPGS4 equation: [c] : (4) atp + dhf + (4) glu-L --> 5dhf + (4) adp + (4) h + (4) pi R_FPGS4m subsystem: Folate Metabolism R_FPGS4m equation: [m] : (4) atp + dhf + (4) glu-L --> 5dhf + (4) adp + (4) h + (4) pi R_FPGS6 subsystem: Folate Metabolism R_FPGS6 equation: [c] : 6dhf + atp + glu-L --> 7dhf + adp + h + pi R_FPGS3 subsystem: Folate Metabolism R_FPGS3 equation: [c] : 6thf + atp + glu-L --> 7thf + adp + h + pi R_FPGS5m subsystem: Folate Metabolism R_FPGS5m equation: [m] : 5dhf + atp + glu-L --> 6dhf + adp + h + pi R_FPGS2m subsystem: Folate Metabolism R_FPGS2m equation: [m] : 5thf + atp + glu-L --> 6thf + adp + h + pi R_FPGS8 subsystem: Folate Metabolism R_FPGS8 equation: [c] : 10fthf5glu + atp + glu-L --> 10fthf6glu + adp + h + pi R_FPGS2 subsystem: Folate Metabolism R_FPGS2 equation: [c] : 5thf + atp + glu-L --> 6thf + adp + h + pi R_FPGS7m subsystem: Folate Metabolism R_FPGS7m equation: [m] : 10fthf + (4) atp + (4) glu-L --> 10fthf5glu + (4) adp + (4) h + (4) pi R_FPGS6m subsystem: Folate Metabolism R_FPGS6m equation: [m] : 6dhf + atp + glu-L --> 7dhf + adp + h + pi R_FPGS9m subsystem: Folate Metabolism R_FPGS9m equation: [m] : 10fthf6glu + atp + glu-L --> 10fthf7glu + adp + h + pi R_FPGS8m subsystem: Folate Metabolism R_FPGS8m equation: [m] : 10fthf5glu + atp + glu-L --> 10fthf6glu + adp + h + pi R_FPGS5 subsystem: Folate Metabolism R…
product: 706790
reactant: 706439
product: 706742
reactant: 706523
product: 706730
product: 706718
product: 706706
fast: false
product: 706875
reactant: 706597
reactant: 706403
product: 706863
reactant: 706609
reactant: 706415
reactant: 706561
product: 706645
reactant: 706379
reactant: 706463
reactant: 706487
product: 706851
product: 706911
reactant: 706573
product: 706633

706657
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stoichiometry: 1.0
species: 587381

587381
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: hexaglutamyl folate (THF)_C44H51N12O21

706766
type: SpeciesReference
stoichiometry: 1.0
species: 587200

706826
type: SpeciesReference
stoichiometry: 1.0
species: 584473

584473
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19

706669
type: SpeciesReference
stoichiometry: 1.0
species: 587441

706754
type: SpeciesReference
stoichiometry: 1.0
species: 584437

584437
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19

706814
type: SpeciesReference
stoichiometry: 1.0
species: 584569

584569
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _10-formyltetrahydrofolate-[Glu](7)_C50H57N13O25

706778
type: SpeciesReference
stoichiometry: 1.0
species: 584533

706427
type: SpeciesReference
stoichiometry: 1.0
species: 587152

706838
type: SpeciesReference
stoichiometry: 1.0
species: 584521

706391
type: SpeciesReference
stoichiometry: 1.0
species: 610608

706511
type: SpeciesReference
stoichiometry: 1.0
species: 587236

587236
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: haxglutamyl folate (DHF)_C44H49N12O21

706681
type: SpeciesReference
stoichiometry: 18.0
species: 607462

706535
type: SpeciesReference
stoichiometry: 1.0
species: 584473

706547
type: SpeciesReference
stoichiometry: 18.0
species: 590751

706621
type: SpeciesReference
stoichiometry: 1.0
species: 584581

706475
type: SpeciesReference
stoichiometry: 1.0
species: 594648

706887
type: SpeciesReference
stoichiometry: 18.0
species: 599581

706802
type: SpeciesReference
stoichiometry: 1.0
species: 587236

706585
type: SpeciesReference
stoichiometry: 1.0
species: 584617

706693
type: SpeciesReference
stoichiometry: 1.0
species: 586832

706500
type: SpeciesReference
stoichiometry: 18.0
species: 598265

706899
type: SpeciesReference
stoichiometry: 18.0
species: 599531

706367
type: SpeciesReference
stoichiometry: 1.0
species: 587345

587345
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: hexaglutamyl folate (THF)_C44H51N12O21

706451
type: SpeciesReference
stoichiometry: 1.0
species: 594612

594612
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _7,8-Dihydrofolate_C19H19N7O6

706790
type: SpeciesReference
stoichiometry: 18.0
species: 589206

706439
type: SpeciesReference
stoichiometry: 18.0
species: 590727

706742
type: SpeciesReference
stoichiometry: 18.0
species: 589230

706523
type: SpeciesReference
stoichiometry: 18.0
species: 598301

706730
type: SpeciesReference
stoichiometry: 18.0
species: 607510

706718
type: SpeciesReference
stoichiometry: 1.0
species: 587152

706706
type: SpeciesReference
stoichiometry: 1.0
species: 587490

587490
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: heptaglutamyl folate (THF)_C49H57N13O24

706875
type: SpeciesReference
stoichiometry: 1.0
species: 587453

706597
type: SpeciesReference
stoichiometry: 1.0
species: 586871

706403
type: SpeciesReference
stoichiometry: 1.0
species: 587381

706863
type: SpeciesReference
stoichiometry: 1.0
species: 586871

706609
type: SpeciesReference
stoichiometry: 1.0
species: 587188

706415
type: SpeciesReference
stoichiometry: 1.0
species: 586832

706561
type: SpeciesReference
stoichiometry: 1.0
species: 584521

706645
type: SpeciesReference
stoichiometry: 1.0
species: 584485

706379
type: SpeciesReference
stoichiometry: 1.0
species: 584485

706463
type: SpeciesReference
stoichiometry: 1.0
species: 584437

706487
type: SpeciesReference
stoichiometry: 1.0
species: 587200

706851
type: SpeciesReference
stoichiometry: 1.0
species: 587405

587405
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: heptaglutamyl folate (DHF)_C49H55N13O24

706911
type: SpeciesReference
stoichiometry: 1.0
species: 587188

706573
type: SpeciesReference
stoichiometry: 1.0
species: 610644

706633
type: SpeciesReference
stoichiometry: 1.0
species: 587345

011172
type: Reaction
is: ENSECAG00000015223.1
is: ENSECAG00000007836.1
reactant: 636513
notes: R_P4502D6 subsystem: CYP Metabolism R_P4502D6 equation: [c] : debrisoquine + h + nadph + o2 --> 4hdebrisoquine + h2o + nadp
is: ENSECAG00000022612.1
product: 636585
product: 636561
is: ENSECAG00000011737.1
name: cytochrome P450 2D6
product: 636573
is: ENSECAG00000023785.1
is: ENSECAG00000021454.1
reactant: 636549
reversible: false
reactant: 636537
is: ENSECAG00000021711.1
reactant: 636525
fast: false

636513
type: SpeciesReference
stoichiometry: 1.0
species: 594153

594153
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: debrisoquine_C10H14N3

636585
type: SpeciesReference
stoichiometry: 1.0
species: 599421

636561
type: SpeciesReference
stoichiometry: 1.0
species: 605370

636573
type: SpeciesReference
stoichiometry: 1.0
species: 586387

586387
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _4 hydroxy debrisoquine_C10H14N3O

636549
type: SpeciesReference
stoichiometry: 1.0
species: 605442

636537
type: SpeciesReference
stoichiometry: 1.0
species: 599531

636525
type: SpeciesReference
stoichiometry: 1.0
species: 605960

601803
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 40_C40H68N2O31

608186
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: L-Proline_C5H9NO2

589872
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Alanine_C3H7NO2

590955
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Bilirubin monoglucuronide_C39H44N4O12

612560
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Xylitol_C5H12O5

585211
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: _2-Hydroxybutyrate_C4H7O3

017793
type: Reaction
reactant: 699420
reactant: 699480
product: 699601
product: 699576
product: 699516
fast: false
reversible: true
product: 699589
reactant: 699444
product: 699540
reactant: 699504
reactant: 699468
reactant: 699492
product: 699528
reactant: 699456
reactant: 699432
notes: R_GSNtl subsystem: Transport, Lysosomal R_GSNtl equation: gsn[l] <==> gsn[c] R_ADEtl subsystem: Transport, Lysosomal R_ADEtl equation: ade[l] <==> ade[c] R_INStl subsystem: Transport, Lysosomal R_INStl equation: ins[l] <==> ins[c] R_Uritl subsystem: Transport, Lysosomal R_Uritl equation: uri[l] <==> uri[c] R_THYMDtl subsystem: Transport, Lysosomal R_THYMDtl equation: thymd[l] <==> thymd[c] R_HXANtl subsystem: Transport, Lysosomal R_HXANtl equation: hxan[l] <==> hxan[c] R_CYTDtl subsystem: Transport, Lysosomal R_CYTDtl equation: cytd[l] <==> cytd[c] R_ADNtl subsystem: Transport, Lysosomal R_ADNtl equation: adn[l] <==> adn[c]
product: 699564
product: 699552
is: ENSECAG00000020891.1

699420
type: SpeciesReference
stoichiometry: 1.0
species: 600816

699480
type: SpeciesReference
stoichiometry: 1.0
species: 589110

589110
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Adenine_C5H5N5

699601
type: SpeciesReference
stoichiometry: 1.0
species: 611841

699576
type: SpeciesReference
stoichiometry: 1.0
species: 589146

699516
type: SpeciesReference
stoichiometry: 1.0
species: 600791

699589
type: SpeciesReference
stoichiometry: 1.0
species: 601190

699444
type: SpeciesReference
stoichiometry: 1.0
species: 593584

593584
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Cytidine_C9H13N3O5

699540
type: SpeciesReference
stoichiometry: 1.0
species: 610800

610800
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Thymidine_C10H14N2O5

699504
type: SpeciesReference
stoichiometry: 1.0
species: 601214

699468
type: SpeciesReference
stoichiometry: 1.0
species: 589170

699492
type: SpeciesReference
stoichiometry: 1.0
species: 610824

699528
type: SpeciesReference
stoichiometry: 1.0
species: 593560

699456
type: SpeciesReference
stoichiometry: 1.0
species: 599048

599048
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Guanosine_C10H13N5O5

699432
type: SpeciesReference
stoichiometry: 1.0
species: 611865

611865
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Uridine_C9H12N2O6

699564
type: SpeciesReference
stoichiometry: 1.0
species: 599024

699552
type: SpeciesReference
stoichiometry: 1.0
species: 589086

016161
type: Reaction
product: 685509
is: http://identifiers.org/ec-code/1.1.1.42
notes: R_ICDHyrm subsystem: Citric Acid Cycle R_ICDHyrm equation: [m] : icit + nadp <==> akg + co2 + nadph
fast: false
is: ENSECAG00000007105.1
name: Isocitrate dehydrogenase (NADP+)
product: 685497
reversible: true
product: 685521
reactant: 685473
reactant: 685485

685509
type: SpeciesReference
stoichiometry: 1.0
species: 589712

685497
type: SpeciesReference
stoichiometry: 1.0
species: 592294

685521
type: SpeciesReference
stoichiometry: 1.0
species: 605454

685473
type: SpeciesReference
stoichiometry: 1.0
species: 600912

685485
type: SpeciesReference
stoichiometry: 1.0
species: 605394

012233
type: Reaction
fast: false
notes: R_LPCOXp subsystem: Lysine Metabolism R_LPCOXp equation: [x] : Lpipecol + o2 --> h + h2o2 + thp2c R_SARCOXp subsystem: Glycine, Serine, and Threonine Metabolism R_SARCOXp equation: [x] : h2o + o2 + sarcs --> fald + gly + h2o2
is: http://identifiers.org/ec-code/1.5.3.1
is: ENSECAG00000020327.1
reactant: 644857
product: 644929
product: 644905
reactant: 644881
product: 644917
reversible: false
reactant: 644869
product: 644941
is: http://identifiers.org/ec-code/1.5.3.7
reactant: 644845
product: 644893

644857
type: SpeciesReference
stoichiometry: 2.0
species: 606021

644929
type: SpeciesReference
stoichiometry: 1.0
species: 598494

644905
type: SpeciesReference
stoichiometry: 1.0
species: 610740

610740
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: _2,3,4,5-Tetrahydropyridine-2-carboxylate_C6H8NO2

644881
type: SpeciesReference
stoichiometry: 1.0
species: 609160

609160
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Sarcosine_C3H7NO2

644917
type: SpeciesReference
stoichiometry: 2.0
species: 599409

644869
type: SpeciesReference
stoichiometry: 1.0
species: 587671

587671
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: L-Pipecolate_C6H11NO2

644941
type: SpeciesReference
stoichiometry: 1.0
species: 599617

644845
type: SpeciesReference
stoichiometry: 1.0
species: 599506

644893
type: SpeciesReference
stoichiometry: 1.0
species: 596444

588590
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: N-Acetyl-D-galactosamine_C8H15NO6

607534
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Phosphate_HO4P

603120
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Leukotriene B4_C20H31O4

586010
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: _3-Oxooctadecanoyl-CoA_C39H64N7O18P3S

018118
type: Reaction
product: 702328
notes: R_GCNTg subsystem: Blood Group Biosynthesis R_GCNTg equation: [g] : galacglcgal14acglcgalgluside_hs + uacgam --> acglcgalacglcgal14acglcgalgluside_hs + h + udp
product: 702316
is: ENSECAG00000000105.1
reactant: 702292
name: N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase
is: http://identifiers.org/ec-code/2.4.1.150
fast: false
reactant: 702304
product: 702340
reversible: false

702328
type: SpeciesReference
stoichiometry: 1.0
species: 611417

702316
type: SpeciesReference
stoichiometry: 1.0
species: 588760

702292
type: SpeciesReference
stoichiometry: 1.0
species: 611381

702304
type: SpeciesReference
stoichiometry: 1.0
species: 597481

702340
type: SpeciesReference
stoichiometry: 1.0
species: 599556

011282
type: Reaction
product: 637055
is: ENSECAG00000010221.1
product: 637068
is: ENSECAG00000005173.1
reactant: 637031
notes: R_AMY1e subsystem: Starch and Sucrose Metabolism R_AMY1e equation: [e] : (8) h2o + strch1 --> (8) glc-D + strch2 R_AMY2e subsystem: Starch and Sucrose Metabolism R_AMY2e equation: [e] : glygn2 + (8) h2o --> (8) glc-D + glygn4
fast: false
reversible: false
is: http://identifiers.org/ec-code/3.2.1.1
is: ENSECAG00000015917.1
is: ENSECAG00000019367.1
reactant: 637019
product: 637080
reactant: 637043

637055
type: SpeciesReference
stoichiometry: 16.0
species: 598109

637068
type: SpeciesReference
stoichiometry: 1.0
species: 609812

637031
type: SpeciesReference
stoichiometry: 1.0
species: 609800

637019
type: SpeciesReference
stoichiometry: 16.0
species: 599433

637080
type: SpeciesReference
stoichiometry: 1.0
species: 598711

637043
type: SpeciesReference
stoichiometry: 1.0
species: 598687

598687
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]})_C66H111O56X

597420
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: D-Galactose_C6H12O6

586996
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _5-Hydroxyindoleacetate_C10H8NO3

596041
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: _16-Glucuronide-estriol_C24H32O9

596937
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)3 (Cer)1_C90H155N4O54FULLRCO

602856
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: (Gal)2-Xyl-L-Ser (protein)_C17H29O14X

017469
type: Reaction
reversible: true
reactant: 696915
reactant: 696939
fast: false
reactant: 696927
product: 696963
product: 696975
is: ENSECAG00000018691.1
product: 696951
notes: R_D_DASH_LACt2 subsystem: Transport, Extracellular R_D_DASH_LACt2 equation: h[e] + lac-D[e] <==> h[c] + lac-D[c] R_L_DASH_LACt2r subsystem: Transport, Extracellular R_L_DASH_LACt2r equation: h[e] + lac-L[e] <==> h[c] + lac-L[c]

696915
type: SpeciesReference
stoichiometry: 2.0
species: 599544

696939
type: SpeciesReference
stoichiometry: 1.0
species: 602880

602880
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: D-Lactate_C3H5O3

696927
type: SpeciesReference
stoichiometry: 1.0
species: 602916

602916
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Lactate_C3H5O3

696963
type: SpeciesReference
stoichiometry: 1.0
species: 602868

696975
type: SpeciesReference
stoichiometry: 2.0
species: 599531

696951
type: SpeciesReference
stoichiometry: 1.0
species: 602904

596576
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Ferrocytochrome C_C42H54FeN8O6S2

608908
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Retinoate_C20H27O2

597554
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Type IB glycolipid_C56H99N2O31FULLRCO

586484
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _4-Methyl-2-oxopentanoate_C6H9O3

009403
type: Reaction
product: 620117
product: 620069
reactant: 619997
reactant: 619985
product: 620093
is: ENSECAG00000022969.1
product: 620153
fast: false
product: 620081
reactant: 620033
product: 620129
product: 620105
product: 620141
reactant: 620021
reactant: 619973
reactant: 620057
reversible: false
notes: R_FAEL184 subsystem: Fatty acid elongation R_FAEL184 equation: [c] : (5) h + malcoa + (4) nadph + o2 + strdnccoa --> co2 + coa + eicostetcoa + (3) h2o + (4) nadp R_FAEL183 subsystem: Fatty acid elongation R_FAEL183 equation: [c] : (5) h + lnlncgcoa + malcoa + (4) nadph + o2 --> co2 + coa + dlnlcgcoa + (3) h2o + (4) nadp R_FAEL205 subsystem: Fatty acid elongation R_FAEL205 equation: [c] : (5) h + malcoa + (4) nadph + o2 + tmndnccoa --> clpndcoa + co2 + coa + (3) h2o + (4) nadp R_FAEL204 subsystem: Fatty acid elongation R_FAEL204 equation: [c] : arachdcoa + (5) h + malcoa + (4) nadph + o2 --> adrncoa + co2 + coa + (3) h2o + (4) nadp
is: http://identifiers.org/ec-code/2.3.1.86
reactant: 620045
reactant: 620009

620117
type: SpeciesReference
stoichiometry: 4.0
species: 592269

620069
type: SpeciesReference
stoichiometry: 1.0
species: 589386

589386
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: adrenyl coenzyme A_C43H66N7O17P3S

619997
type: SpeciesReference
stoichiometry: 1.0
species: 609836

609836
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: stearidonyl coenzyme A_C39H58N7O17P3S

619985
type: SpeciesReference
stoichiometry: 1.0
species: 590475

620093
type: SpeciesReference
stoichiometry: 16.0
species: 605370

620153
type: SpeciesReference
stoichiometry: 1.0
species: 595811

595811
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: eicosatetranoyl coenzyme A_C41H62N7O17P3S

620081
type: SpeciesReference
stoichiometry: 4.0
species: 592342

620033
type: SpeciesReference
stoichiometry: 4.0
species: 605960

620129
type: SpeciesReference
stoichiometry: 1.0
species: 594868

594868
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: dihomo-gamma-linolenyl coenzyme A_C41H64N7O17P3S

620105
type: SpeciesReference
stoichiometry: 1.0
species: 592075

592075
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: clupanodonyl CoA_C43H64N7O17P3S

620141
type: SpeciesReference
stoichiometry: 12.0
species: 599421

620021
type: SpeciesReference
stoichiometry: 1.0
species: 603530

603530
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: gamma-linolenoyl-CoA_C39H60N7O17P3S

619973
type: SpeciesReference
stoichiometry: 4.0
species: 604197

620057
type: SpeciesReference
stoichiometry: 16.0
species: 605442

620045
type: SpeciesReference
stoichiometry: 20.0
species: 599531

620009
type: SpeciesReference
stoichiometry: 1.0
species: 610909

610909
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: timnodonyl coenzyme A_C41H60N7O17P3S

018286
type: Reaction
is: http://identifiers.org/ec-code/1.14.99.9
product: 703350
reactant: 703206
product: 703290
reactant: 703242
product: 703302
reactant: 703266
reactant: 703230
notes: R_P45017A4r subsystem: Steroid Metabolism R_P45017A4r equation: [r] : 17ahprgstrn + h + nadph + (0.5) o2 --> acald + andrstndn + h2o + nadp R_P45017A2r subsystem: Steroid Metabolism R_P45017A2r equation: [r] : 17ahprgnlone + h + nadph + (0.5) o2 --> acald + dhea + h2o + nadp R_P45017A1r subsystem: Steroid Metabolism R_P45017A1r equation: [r] : h + nadph + o2 + prgnlone --> 17ahprgnlone + h2o + nadp R_P45017A3r subsystem: Steroid Metabolism R_P45017A3r equation: [r] : h + nadph + o2 + prgstrn --> 17ahprgstrn + h2o + nadp
reversible: false
product: 703278
product: 703314
reactant: 703254
product: 703326
fast: false
product: 703338
reactant: 703218
reactant: 703194
is: ENSECAG00000010022.1

703350
type: SpeciesReference
stoichiometry: 1.0
species: 584846

584846
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _17alpha-Hydroxyprogesterone_C21H30O3

703206
type: SpeciesReference
stoichiometry: 1.0
species: 608006

608006
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Progesterone_C21H30O2

703290
type: SpeciesReference
stoichiometry: 1.0
species: 594564

594564
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Dehydroepiandrosterone_C19H28O2

703242
type: SpeciesReference
stoichiometry: 1.0
species: 584822

584822
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _17alpha-Hydroxypregnenolone_C21H32O3

703302
type: SpeciesReference
stoichiometry: 4.0
species: 599493

703266
type: SpeciesReference
stoichiometry: 1.0
species: 584846

703230
type: SpeciesReference
stoichiometry: 4.0
species: 605479

703278
type: SpeciesReference
stoichiometry: 2.0
species: 588384

588384
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Acetaldehyde_C2H4O

703314
type: SpeciesReference
stoichiometry: 1.0
species: 590138

703254
type: SpeciesReference
stoichiometry: 4.0
species: 599605

703326
type: SpeciesReference
stoichiometry: 4.0
species: 605418

703338
type: SpeciesReference
stoichiometry: 1.0
species: 584822

703218
type: SpeciesReference
stoichiometry: 1.0
species: 607958

703194
type: SpeciesReference
stoichiometry: 3.0
species: 606008

012005
type: Reaction
is: ENSECAG00000020065.1
product: 643246
product: 643210
product: 643186
fast: false
product: 643222
product: 643162
reactant: 643126
reactant: 643078
reactant: 643054
reactant: 643102
reactant: 643090
product: 643174
product: 643138
reactant: 643066
reversible: true
reactant: 643042
reactant: 643114
reactant: 643030
notes: R_FA160ACPH subsystem: Fatty Acid Metabolism R_FA160ACPH equation: [c] : h2o + palmACP <==> ACP + h + hdca R_FA181ACPH subsystem: Fatty Acid Metabolism R_FA181ACPH equation: [c] : h2o + octeACP <==> ACP + h + ocdcea R_FA120ACPH subsystem: Fatty Acid Metabolism R_FA120ACPH equation: [c] : ddcaACP + h2o <==> ACP + ddca + h R_FA182ACPH subsystem: Fatty Acid Metabolism R_FA182ACPH equation: [c] : h2o + ocdcyaACP <==> ACP + h + ocdcya R_FA140ACPH subsystem: Fatty Acid Metabolism R_FA140ACPH equation: [c] : h2o + myrsACP <==> ACP + h + ttdca R_FA141ACPH subsystem: Fatty Acid Metabolism R_FA141ACPH equation: [c] : h2o + tdeACP <==> ACP + h + ttdcea R_FA161ACPH subsystem: Fatty Acid Metabolism R_FA161ACPH equation: [c] : h2o + hdeACP <==> ACP + h + hdcea R_FA180ACPH subsystem: Fatty Acid Metabolism R_FA180ACPH equation: [c] : h2o + ocdcaACP <==> ACP + h + ocdca
product: 643198
product: 643150
is: http://identifiers.org/ec-code/3.1.2.14
product: 643234

643246
type: SpeciesReference
stoichiometry: 1.0
species: 611261

643210
type: SpeciesReference
stoichiometry: 1.0
species: 606251

643186
type: SpeciesReference
stoichiometry: 1.0
species: 606227

606227
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: octadecanoate (n-C18:0)_C18H35O2

643222
type: SpeciesReference
stoichiometry: 1.0
species: 606287

606287
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: octadecadienoate (n-C18:2)_C18H31O2

643162
type: SpeciesReference
stoichiometry: 1.0
species: 594105

594105
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dodecanoate (n-C12:0)_C12H23O2

643126
type: SpeciesReference
stoichiometry: 8.0
species: 599421

643078
type: SpeciesReference
stoichiometry: 1.0
species: 606215

606215
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Octadecanoyl-ACP (n-C18:0ACP)_C29H55N2O8PRS

643054
type: SpeciesReference
stoichiometry: 1.0
species: 610223

610223
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)_C25H45N2O8PRS

643102
type: SpeciesReference
stoichiometry: 1.0
species: 594092

594092
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dodecanoyl-ACP (n-C12:0ACP)_C23H43N2O8PRS

643090
type: SpeciesReference
stoichiometry: 1.0
species: 599917

599917
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)_C27H49N2O8PRS

643174
type: SpeciesReference
stoichiometry: 1.0
species: 599797

643138
type: SpeciesReference
stoichiometry: 1.0
species: 599749

643066
type: SpeciesReference
stoichiometry: 1.0
species: 606275

643042
type: SpeciesReference
stoichiometry: 1.0
species: 606893

643114
type: SpeciesReference
stoichiometry: 1.0
species: 605031

643030
type: SpeciesReference
stoichiometry: 1.0
species: 606311

606311
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)_C29H53N2O8PRS

643198
type: SpeciesReference
stoichiometry: 8.0
species: 587502

587502
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: acyl carrier protein_C11H21N2O7PRS

643150
type: SpeciesReference
stoichiometry: 1.0
species: 611249

611249
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: tetradecanoate (n-C14:0)_C14H27O2

643234
type: SpeciesReference
stoichiometry: 8.0
species: 599531

588953
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: N-Acetylneuraminate_C11H18NO9

594684
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425

596239
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Ethanol_C2H6O

593233
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 5_C31H47NO35S3

610524
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425

008776
type: Reaction
fast: false
is: ENSECAG00000005685.1
name: retinol dehydrogenase (all-trans,NADPH)
product: 614698
is: http://identifiers.org/ec-code/1.1.1.105
reactant: 614662
reactant: 614650
product: 614674
reversible: true
product: 614686
is: ENSECAG00000008479.1
notes: R_RDH1a subsystem: Vitamin A Metabolism R_RDH1a equation: [c] : nadp + retinol <==> h + nadph + retinal

614698
type: SpeciesReference
stoichiometry: 1.0
species: 605442

614662
type: SpeciesReference
stoichiometry: 1.0
species: 605370

614650
type: SpeciesReference
stoichiometry: 1.0
species: 608883

614674
type: SpeciesReference
stoichiometry: 1.0
species: 599531

614686
type: SpeciesReference
stoichiometry: 1.0
species: 608835

593488
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Hydrogen cyanide_CHN

597360
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341

013115
type: Reaction
product: 653197
product: 653245
reactant: 653125
reactant: 653161
is: http://identifiers.org/ec-code/1.1.1.34
reactant: 653149
reactant: 653185
reversible: false
fast: false
notes: R_HMGCOARr subsystem: Cholesterol Metabolism R_HMGCOARr equation: [r] : (2) h + hmgcoa + (2) nadph --> coa + mev-R + (2) nadp R_HMGCOARx subsystem: Cholesterol Metabolism R_HMGCOARx equation: [x] : (2) h + hmgcoa + (2) nadph --> coa + mev-R + (2) nadp
product: 653209
reactant: 653137
product: 653233
reactant: 653173
product: 653257
product: 653221
is: ENSECAG00000021330.1

653197
type: SpeciesReference
stoichiometry: 2.0
species: 605430

605430
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

653245
type: SpeciesReference
stoichiometry: 2.0
species: 605418

653125
type: SpeciesReference
stoichiometry: 1.0
species: 600112

653161
type: SpeciesReference
stoichiometry: 2.0
species: 605491

605491
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

653149
type: SpeciesReference
stoichiometry: 2.0
species: 599617

653185
type: SpeciesReference
stoichiometry: 2.0
species: 599605

653209
type: SpeciesReference
stoichiometry: 1.0
species: 592414

653137
type: SpeciesReference
stoichiometry: 2.0
species: 605479

653233
type: SpeciesReference
stoichiometry: 1.0
species: 604608

604608
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: (R)-Mevalonate_C6H11O4

653173
type: SpeciesReference
stoichiometry: 1.0
species: 600125

653257
type: SpeciesReference
stoichiometry: 1.0
species: 604620

604620
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: (R)-Mevalonate_C6H11O4

653221
type: SpeciesReference
stoichiometry: 1.0
species: 592402

610969
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: tolbutamide_C12H18N2O3S

018887
type: Reaction
reactant: 711368
product: 711404
product: 711392
notes: R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_PROSTGE2t subsystem: Transport, Extracellular R_PROSTGE2t equation: hco3[c] + prostge2[e] <==> hco3[e] + prostge2[c]
fast: false
reactant: 711344
reactant: 711356
product: 711380
reversible: true
is: ENSECAG00000013398.1

711368
type: SpeciesReference
stoichiometry: 1.0
species: 596138

711404
type: SpeciesReference
stoichiometry: 2.0
species: 599701

711392
type: SpeciesReference
stoichiometry: 1.0
species: 608271

711344
type: SpeciesReference
stoichiometry: 2.0
species: 599689

711356
type: SpeciesReference
stoichiometry: 1.0
species: 608283

711380
type: SpeciesReference
stoichiometry: 1.0
species: 596125

010785
type: Reaction
reversible: false
notes: R_GLDBRAN subsystem: Starch and Sucrose Metabolism R_GLDBRAN equation: [c] : dxtrn + h2o --> glc-D + glygn3
product: 633005
product: 632993
is: ENSECAG00000010571.1
reactant: 632981
name: glycogen debranching enzyme
is: http://identifiers.org/ec-code/3.2.1.33
fast: false
reactant: 632969

633005
type: SpeciesReference
stoichiometry: 1.0
species: 598097

632993
type: SpeciesReference
stoichiometry: 1.0
species: 598699

598699
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: glycogen, structure 3 (glycogenin-7[1,4-Glc])_C42H71O36X

632981
type: SpeciesReference
stoichiometry: 1.0
species: 599421

632969
type: SpeciesReference
stoichiometry: 1.0
species: 595678

595678
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: phosphorylase-limit dextrin (glycogenin-1,6{4[1,4-Glc], 4[1,4-Glc]})_C48H81O41X

015355
type: Reaction
product: 675326
reactant: 675314
product: 675338
is: ENSECAG00000000458.1
product: 675350
reactant: 675290
reactant: 675302
fast: false
reactant: 675278
reversible: false
notes: R_AKR1D2 subsystem: Bile Acid Biosynthesis R_AKR1D2 equation: [c] : h + nadph + xoldiolone --> nadp + xoldioloneh R_AKR1D subsystem: Bile Acid Biosynthesis R_AKR1D equation: [c] : h + nadph + xol7aone --> nadp + xol7ah

675326
type: SpeciesReference
stoichiometry: 1.0
species: 612277

612277
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _7alpha-Hydroxy-5beta-cholestan-3-one_C27H46O2

675314
type: SpeciesReference
stoichiometry: 2.0
species: 605442

675338
type: SpeciesReference
stoichiometry: 2.0
species: 605370

675350
type: SpeciesReference
stoichiometry: 1.0
species: 612337

612337
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one_C27H46O3

675290
type: SpeciesReference
stoichiometry: 1.0
species: 612289

675302
type: SpeciesReference
stoichiometry: 2.0
species: 599531

675278
type: SpeciesReference
stoichiometry: 1.0
species: 612313

612313
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _7alpha,12alpha-Dihydroxycholest-4-en-3-one_C27H44O3

010990
type: Reaction
is: ENSECAG00000008933.1
is: ENSECAG00000010549.1
reactant: 635066
product: 635102
reversible: false
product: 635090
reactant: 635078
notes: R_GLUNm subsystem: Glutamate metabolism R_GLUNm equation: [m] : gln-L + h2o --> glu-L + nh4
fast: false
is: http://identifiers.org/ec-code/3.5.1.2
name: glutaminase (mitochondrial)

635066
type: SpeciesReference
stoichiometry: 1.0
species: 598229

635102
type: SpeciesReference
stoichiometry: 1.0
species: 598301

635090
type: SpeciesReference
stoichiometry: 1.0
species: 605587

635078
type: SpeciesReference
stoichiometry: 1.0
species: 599469

607098
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Pyridoxine 5'-phosphate_C8H10NO6P

593197
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 2_C45H66N2O49S4

009513
type: Reaction
reversible: true
name: carnitine dimethyl nonanoyl transferase, revsible, peroxisomal
product: 621503
fast: false
reactant: 621491
reactant: 621479
product: 621515
notes: R_CSNAT2x subsystem: Fatty Acid Metabolism R_CSNAT2x equation: [x] : crn + dmnoncoa <==> coa + dmnoncrn
is: http://identifiers.org/ec-code/2.3.1.7
is: ENSECAG00000008829.1

621503
type: SpeciesReference
stoichiometry: 1.0
species: 592414

621491
type: SpeciesReference
stoichiometry: 1.0
species: 592680

621479
type: SpeciesReference
stoichiometry: 1.0
species: 594988

621515
type: SpeciesReference
stoichiometry: 1.0
species: 595000

015943
type: Reaction
fast: false
modifier: 682555
modifier: 682531
is: http://identifiers.org/ec-code/2.1.2.1
reactant: 682494
reversible: false
is: ENSECAG00000021295.1
reactant: 682482
modifier: 682579
notes: R_GHMT2rm subsystem: Glycine, Serine, and Threonine Metabolism R_GHMT2rm equation: [m] : ser-L + thf <==> gly + h2o + mlthf R_GHMT3m subsystem: Lysine Metabolism R_GHMT3m equation: [m] : 3htmelys + h --> 4tmeabut + gly
modifier: 682543
product: 682519
modifier: 682567
product: 682507

682494
type: SpeciesReference
stoichiometry: 1.0
species: 599581

682482
type: SpeciesReference
stoichiometry: 1.0
species: 585791

585791
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _3-Hydroxy-N6,N6,N6-trimethyl-L-lysine_C9H20N2O3

609376
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Serine_C3H7NO3

682519
type: SpeciesReference
stoichiometry: 1.0
species: 598482

682507
type: SpeciesReference
stoichiometry: 1.0
species: 586640

606588
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

014635
type: Reaction
product: 668482
reactant: 668446
is: ENSECAG00000015945.1
reactant: 668458
reactant: 668434
reversible: true
notes: R_GLCURtly subsystem: Transport, Lysosomal R_GLCURtly equation: glcur[c] + h[c] <==> glcur[l] + h[l] R_IDOURtly subsystem: Transport, Lysosomal R_IDOURtly equation: h[c] + idour[c] <==> h[l] + idour[l] R_ACNAMlt subsystem: Transport, Lysosomal R_ACNAMlt equation: acnam[c] + h[c] <==> acnam[l] + h[l]
product: 668519
fast: false
reactant: 668470
product: 668495
product: 668507

668482
type: SpeciesReference
stoichiometry: 1.0
species: 588941

588941
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: N-Acetylneuraminate_C11H18NO9

668446
type: SpeciesReference
stoichiometry: 1.0
species: 600960

600960
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Iduronate_C6H9O7

668458
type: SpeciesReference
stoichiometry: 1.0
species: 588929

588929
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-Acetylneuraminate_C11H18NO9

668434
type: SpeciesReference
stoichiometry: 1.0
species: 598181

668519
type: SpeciesReference
stoichiometry: 1.0
species: 600972

600972
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: L-Iduronate_C6H9O7

668470
type: SpeciesReference
stoichiometry: 3.0
species: 599531

668495
type: SpeciesReference
stoichiometry: 3.0
species: 599568

668507
type: SpeciesReference
stoichiometry: 1.0
species: 598193

607025
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Procollagen 5-hydroxy-L-lysine_C6H14N2O3

597216
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: (alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C82H137N2O65X

596113
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: estrone glucuronide_C24H30O8

016875
type: Reaction
is: http://identifiers.org/ec-code/4.3.1.4
product: 690742
notes: R_GluForTx subsystem: Histidine Metabolism R_GluForTx equation: [c] : forglu + h + thf --> 5forthf + glu-L R_FTCD subsystem: Folate Metabolism R_FTCD equation: [c] : 5forthf + (2) h --> methf + nh4
reactant: 690694
product: 690754
reactant: 690718
reactant: 690730
fast: false
product: 690766
is: ENSECAG00000011979.1
reactant: 690706
product: 690778
is: http://identifiers.org/ec-code/2.1.2.5
reversible: false

690742
type: SpeciesReference
stoichiometry: 1.0
species: 605563

690694
type: SpeciesReference
stoichiometry: 1.0
species: 610608

690754
type: SpeciesReference
stoichiometry: 1.0
species: 604584

690718
type: SpeciesReference
stoichiometry: 1.0
species: 586897

586897
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5-Formiminotetrahydrofolate_C20H22N8O6

690730
type: SpeciesReference
stoichiometry: 3.0
species: 599531

690766
type: SpeciesReference
stoichiometry: 1.0
species: 598265

690706
type: SpeciesReference
stoichiometry: 1.0
species: 596672

596672
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-Formimidoyl-L-glutamate_C6H8N2O4

690778
type: SpeciesReference
stoichiometry: 1.0
species: 586897

592992
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 4_C31H49NO29S

014080
type: Reaction
notes: R_PDE1 subsystem: Nucleotides R_PDE1 equation: [c] : camp + h2o --> amp + h
reversible: false
is: ENSECAG00000020846.1
is: ENSECAG00000008059.1
is: ENSECAG00000012189.1
product: 663037
reactant: 663013
product: 663025
is: ENSECAG00000016256.1
is: ENSECAG00000017565.1
is: ENSECAG00000023182.1
is: ENSECAG00000007337.1
name: _3',5'-cyclic-nucleotide phosphodiesterase
fast: false
is: http://identifiers.org/ec-code/3.1.4.17
reactant: 663001

663037
type: SpeciesReference
stoichiometry: 1.0
species: 599531

663013
type: SpeciesReference
stoichiometry: 1.0
species: 599421

663025
type: SpeciesReference
stoichiometry: 1.0
species: 590041

663001
type: SpeciesReference
stoichiometry: 1.0
species: 591320

612058
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Vitamin D3_C27H44O

591604
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N,N'-Diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1185H1940N20O170P20

601081
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Imidazole-4-acetate_C5H5N2O2

017709
type: Reaction
reactant: 698938
reactant: 698926
reversible: false
product: 698987
reactant: 698951
fast: false
is: ENSECAG00000021990.1
reactant: 698963
product: 698999
notes: R_COQ7m subsystem: Ubiquinone Biosynthesis R_COQ7m equation: [m] : 2dp6mobq_me + h + nadph + o2 --> 2dpmhobq + h2o + nadp
product: 698975
name: Ubiquinone biosynthesis COQ7

698938
type: SpeciesReference
stoichiometry: 1.0
species: 605454

698926
type: SpeciesReference
stoichiometry: 1.0
species: 585150

585150
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _2-Decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone_C58H88O3

698987
type: SpeciesReference
stoichiometry: 1.0
species: 585162

698951
type: SpeciesReference
stoichiometry: 1.0
species: 605984

698963
type: SpeciesReference
stoichiometry: 1.0
species: 599581

698999
type: SpeciesReference
stoichiometry: 1.0
species: 605394

698975
type: SpeciesReference
stoichiometry: 1.0
species: 599469

012077
type: Reaction
product: 643763
reversible: false
fast: false
product: 643775
reactant: 643751
name: gamma-glutamylcyclotransferase
is: http://identifiers.org/ec-code/2.3.2.4
notes: R_GGLUCT subsystem: Glutathione Metabolism R_GGLUCT equation: gluala[e] --> 5oxpro[c] + ala-L[c]
is: ENSECAG00000017845.1

643763
type: SpeciesReference
stoichiometry: 1.0
species: 587128

643775
type: SpeciesReference
stoichiometry: 1.0
species: 589834

643751
type: SpeciesReference
stoichiometry: 1.0
species: 598326

606673
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)_C9H13O18P4FULLRCO2FULLR2CO2

600418
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: heparan sulfate, degradation product 21_C37H55NO38S2

604331
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Mannose_C6H12O6

599785
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Hexadecanoate (n-C16:0)_C16H31O2

013430
type: Reaction
is: http://identifiers.org/ec-code/2.7.8.8
reversible: true
product: 658129
fast: false
is: ENSECAG00000016050.1
product: 658141
reactant: 658105
notes: R_PSSA1_hs subsystem: Glycerophospholipid Metabolism R_PSSA1_hs equation: [c] : pchol_hs + ser-L <==> chol + ps_hs
name: Phosphatidylserine synthase homo sapiens
reactant: 658117

658129
type: SpeciesReference
stoichiometry: 1.0
species: 591628

658141
type: SpeciesReference
stoichiometry: 1.0
species: 608404

658105
type: SpeciesReference
stoichiometry: 1.0
species: 609352

658117
type: SpeciesReference
stoichiometry: 1.0
species: 606965

019091
type: Reaction
reactant: 713398
is: ENSECAG00000019280.1
reversible: true
product: 713425
notes: R_GK1 subsystem: Nucleotides R_GK1 equation: [c] : atp + gmp <==> adp + gdp R_DGK1 subsystem: Nucleotides R_DGK1 equation: [c] : atp + dgmp <==> adp + dgdp
is: http://identifiers.org/ec-code/2.7.4.8
fast: false
product: 713451
reactant: 713411
product: 713438
reactant: 713385

713398
type: SpeciesReference
stoichiometry: 1.0
species: 598808

713425
type: SpeciesReference
stoichiometry: 1.0
species: 597940

713451
type: SpeciesReference
stoichiometry: 1.0
species: 594227

713411
type: SpeciesReference
stoichiometry: 2.0
species: 590727

713438
type: SpeciesReference
stoichiometry: 2.0
species: 589206

713385
type: SpeciesReference
stoichiometry: 1.0
species: 594263

594263
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: dGMP_C10H12N5O7P

016758
type: Reaction
reactant: 689913
reactant: 689937
is: http://identifiers.org/ec-code/2.7.1.137
reactant: 689901
product: 689973
is: ENSECAG00000014963.1
reactant: 689925
notes: R_PIK3 subsystem: Inositol Phosphate Metabolism R_PIK3 equation: [c] : atp + pail_hs --> adp + h + pail3p_hs R_PI5P3K subsystem: Inositol Phosphate Metabolism R_PI5P3K equation: [c] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI4P3K subsystem: Inositol Phosphate Metabolism R_PI4P3K equation: [c] : atp + pail4p_hs --> adp + h + pail34p_hs
product: 689997
fast: false
reversible: false
product: 689961
product: 689985
product: 689949
is: ENSECAG00000022941.1

689913
type: SpeciesReference
stoichiometry: 3.0
species: 590727

689937
type: SpeciesReference
stoichiometry: 1.0
species: 606795

689901
type: SpeciesReference
stoichiometry: 1.0
species: 606831

689973
type: SpeciesReference
stoichiometry: 3.0
species: 589206

689925
type: SpeciesReference
stoichiometry: 1.0
species: 606855

689997
type: SpeciesReference
stoichiometry: 3.0
species: 599531

689961
type: SpeciesReference
stoichiometry: 1.0
species: 606698

689985
type: SpeciesReference
stoichiometry: 1.0
species: 606746

689949
type: SpeciesReference
stoichiometry: 1.0
species: 606722

589302
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: ADPribose 2'-phosphate_C15H20N5O17P3

596252
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: F1alpha_C22H37N2O15X

595194
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dolichyl phosphate D-mannose, human uterine homolog_C1085H1780O90P10

015655
type: Reaction
reversible: true
is: http://identifiers.org/ec-code/4.2.1.55
fast: false
is: ENSECAG00000013217.1
name: _3-hydroxybutyryl-CoA dehydratase, mitochondrial
reactant: 678502
notes: R_3HBCDm subsystem: Butanoate Metabolism R_3HBCDm equation: [m] : b2coa + h2o <==> 3hbcoa-R
reactant: 678514
product: 678526

678502
type: SpeciesReference
stoichiometry: 1.0
species: 599469

678514
type: SpeciesReference
stoichiometry: 1.0
species: 590799

678526
type: SpeciesReference
stoichiometry: 1.0
species: 585658

585658
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401

010302
type: Reaction
product: 628657
notes: R_NCCt subsystem: Transport, Extracellular R_NCCt equation: cl[e] + na1[e] --> cl[c] + na1[c]
reactant: 628633
product: 628645
is: ENSECAG00000022414.1
name: Na+-Cl- cotransport
reversible: false
fast: false
reactant: 628621
is: ENSECAG00000014101.1

628657
type: SpeciesReference
stoichiometry: 1.0
species: 605187

628633
type: SpeciesReference
stoichiometry: 1.0
species: 592039

628645
type: SpeciesReference
stoichiometry: 1.0
species: 592027

628621
type: SpeciesReference
stoichiometry: 1.0
species: 605200

593040
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: chondroitin sulfate C (GalNAc6S-GlcA), precursor 3_C45H67N2O42S2X

595799
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: eicosatetranoic acid_C20H31O2

604850
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: myo-Inositol hexakisphosphate_C6H6O24P6

009245
type: Reaction
product: 618985
reactant: 618925
is: http://identifiers.org/ec-code/2.8.2.2
is: ENSECAG00000000863.1
reactant: 618949
reactant: 618937
notes: R_ESTSULT subsystem: Steroid Metabolism R_ESTSULT equation: [c] : estrone + paps --> estrones + h + pap R_DHEASULT subsystem: Steroid Metabolism R_DHEASULT equation: [c] : dhea + paps --> dheas + h + pap
is: ENSECAG00000017499.1
product: 618961
product: 618973
is: http://identifiers.org/ec-code/2.8.2.4
fast: false
product: 618997
reversible: false

618985
type: SpeciesReference
stoichiometry: 1.0
species: 594576

618925
type: SpeciesReference
stoichiometry: 1.0
species: 594552

594552
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dehydroepiandrosterone_C19H28O2

618949
type: SpeciesReference
stoichiometry: 2.0
species: 606941

618937
type: SpeciesReference
stoichiometry: 1.0
species: 596065

596065
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Estrone_C18H22O2

618961
type: SpeciesReference
stoichiometry: 1.0
species: 596125

618973
type: SpeciesReference
stoichiometry: 2.0
species: 606917

618997
type: SpeciesReference
stoichiometry: 2.0
species: 599531

593329
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5b_C45H64N2O51S5X

017265
type: Reaction
reversible: false
reactant: 694101
product: 694137
is: ENSECAG00000017477.1
reactant: 694065
fast: false
is: ENSECAG00000009444.1
product: 694125
is: http://identifiers.org/ec-code/2.7.7.15
product: 694113
reactant: 694089
reactant: 694077
notes: R_CHLPCTD subsystem: Glycerophospholipid Metabolism R_CHLPCTD equation: [c] : cholp + ctp + h --> cdpchol + ppi R_CPCTDTX subsystem: Glycerophospholipid Metabolism R_CPCTDTX equation: [c] : ctp + h + ntm2amep --> cmpntm2amep + ppi

694101
type: SpeciesReference
stoichiometry: 2.0
species: 593439

694137
type: SpeciesReference
stoichiometry: 2.0
species: 607728

694065
type: SpeciesReference
stoichiometry: 1.0
species: 591809

694125
type: SpeciesReference
stoichiometry: 1.0
species: 592245

592245
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341

694113
type: SpeciesReference
stoichiometry: 1.0
species: 591519

591519
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: CDPcholine_C14H25N4O11P2

694089
type: SpeciesReference
stoichiometry: 2.0
species: 599531

694077
type: SpeciesReference
stoichiometry: 1.0
species: 605936

605936
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: N-Trimethyl-2-aminoethylphosphonate_C5H13NO3P

586339
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _4-Fumarylacetoacetate_C8H6O6

610776
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Thymine_C5H6N2O2

603192
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: lignoceric acid_C24H47O2

016015
type: Reaction
product: 683187
reactant: 683122
product: 683135
reversible: false
is: ENSECAG00000012424.1
product: 683212
fast: false
product: 683161
reactant: 683085
notes: R_UDPGP subsystem: Starch and Sucrose Metabolism R_UDPGP equation: [c] : h2o + udpg --> g1p + (2) h + ump R_NNAT subsystem: NAD Metabolism R_NNAT equation: [c] : atp + h + nicrnt --> dnad + ppi R_DNADDP subsystem: NAD Metabolism R_DNADDP equation: [c] : dnad + h2o --> amp + (2) h + nicrnt
reactant: 683060
is: ENSECAG00000003776.1
product: 683174
reactant: 683097
is: http://identifiers.org/ec-code/2.7.7.18
reactant: 683110
product: 683148
product: 683200
is: ENSECAG00000007018.1
reactant: 683073
is: http://identifiers.org/ec-code/3.6.1.9

683187
type: SpeciesReference
stoichiometry: 4.0
species: 599531

683122
type: SpeciesReference
stoichiometry: 1.0
species: 595060

595060
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Deamino-NAD+_C21H24N6O15P2

683135
type: SpeciesReference
stoichiometry: 1.0
species: 605648

605648
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Nicotinate D-ribonucleotide_C11H12NO9P

683212
type: SpeciesReference
stoichiometry: 1.0
species: 607728

683161
type: SpeciesReference
stoichiometry: 1.0
species: 597204

683085
type: SpeciesReference
stoichiometry: 1.0
species: 590727

683060
type: SpeciesReference
stoichiometry: 1.0
species: 605648

683174
type: SpeciesReference
stoichiometry: 1.0
species: 590041

683097
type: SpeciesReference
stoichiometry: 2.0
species: 599421

683110
type: SpeciesReference
stoichiometry: 1.0
species: 599531

683148
type: SpeciesReference
stoichiometry: 1.0
species: 611660

683200
type: SpeciesReference
stoichiometry: 1.0
species: 595060

683073
type: SpeciesReference
stoichiometry: 1.0
species: 611525

018082
type: Reaction
product: 702135
is: http://identifiers.org/ec-code/1.3.99.1
product: 702147
reactant: 702123
reactant: 702111
is: ENSECAG00000014215.1
notes: R_SUCD1m subsystem: Citric Acid Cycle R_SUCD1m equation: [m] : fad + succ <==> fadh2 + fum
is: ENSECAG00000011758.1
fast: false
is: ENSECAG00000000397.1
name: succinate dehydrogenase
reversible: true

702135
type: SpeciesReference
stoichiometry: 1.0
species: 596372

702147
type: SpeciesReference
stoichiometry: 1.0
species: 597119

597119
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Fumarate_C4H2O4

702123
type: SpeciesReference
stoichiometry: 1.0
species: 596324

702111
type: SpeciesReference
stoichiometry: 1.0
species: 609921

009902
type: Reaction
reactant: 624928
product: 624952
notes: R_G3PD1 subsystem: Glycerophospholipid Metabolism R_G3PD1 equation: [c] : glyc3p + nad <==> dhap + h + nadh
name: glycerol-3-phosphate dehydrogenase (NAD)
is: http://identifiers.org/ec-code/1.1.1.94
reversible: true
product: 624964
is: ENSECAG00000001568.1
reactant: 624916
product: 624940
fast: false

624928
type: SpeciesReference
stoichiometry: 1.0
species: 598542

624952
type: SpeciesReference
stoichiometry: 1.0
species: 599531

624964
type: SpeciesReference
stoichiometry: 1.0
species: 605322

624916
type: SpeciesReference
stoichiometry: 1.0
species: 605248

624940
type: SpeciesReference
stoichiometry: 1.0
species: 594396

596432
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Formaldehyde_CH2O

594068
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: trans-Dodec-2-enoyl-CoA_C33H52N7O17P3S

597023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Type IIIH glycolipid_C70H122N3O40FULLRCO

594480
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425

603758
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: (alpha-D-mannosyl)2-beta-D-mannosyl-N-acetylglucosamine_C26H45NO21

595132
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Dolichyl beta-D-glucosyl phosphate, human liver homolog_C1140H1868O90P10

011799
type: Reaction
is: http://identifiers.org/ec-code/1.2.1.38
product: 641536
product: 641524
product: 641464
product: 641452
reactant: 641368
is: http://identifiers.org/ec-code/1.2.1.41
reversible: false
product: 641512
product: 641500
reactant: 641380
is: http://identifiers.org/ec-code/1.2.1.21
notes: R_LCADim subsystem: Pyruvate Metabolism R_LCADim equation: [m] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDDm subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDDm equation: [m] : gcald + h2o + nad --> glyclt + (2) h + nadh R_G5SDym subsystem: Urea cycle/amino group metabolism R_G5SDym equation: [m] : glu5p + h + nadph --> glu5sa + nadp + pi R_GLU5Km subsystem: Urea cycle/amino group metabolism R_GLU5Km equation: [m] : atp + glu-L --> adp + glu5p R_AGPRim subsystem: Urea cycle/amino group metabolism R_AGPRim equation: [m] : acg5p + h + nadph --> acg5sa + nadp + pi R_LCADi_Dm subsystem: Pyruvate Metabolism R_LCADi_Dm equation: [m] : h2o + lald-D + nad --> (2) h + lac-D + nadh
product: 641560
reactant: 641344
is: http://identifiers.org/ec-code/2.7.2.11
reactant: 641392
reactant: 641332
reactant: 641428
reactant: 641404
is: ENSECAG00000016847.1
reactant: 641440
reactant: 641356
fast: false
product: 641573
product: 641548
reactant: 641320
reactant: 641416
product: 641488
product: 641476

641536
type: SpeciesReference
stoichiometry: 1.0
species: 602928

641524
type: SpeciesReference
stoichiometry: 1.0
species: 598253

598253
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Glutamate 5-semialdehyde_C5H9NO3

641464
type: SpeciesReference
stoichiometry: 1.0
species: 588542

588542
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: N-Acetyl-L-glutamate 5-semialdehyde_C7H10NO4

641452
type: SpeciesReference
stoichiometry: 1.0
species: 598241

598241
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Glutamate 5-phosphate_C5H8NO7P

641368
type: SpeciesReference
stoichiometry: 1.0
species: 590751

641512
type: SpeciesReference
stoichiometry: 1.0
species: 602892

641500
type: SpeciesReference
stoichiometry: 1.0
species: 589230

641380
type: SpeciesReference
stoichiometry: 1.0
species: 588530

641560
type: SpeciesReference
stoichiometry: 6.0
species: 599581

641344
type: SpeciesReference
stoichiometry: 1.0
species: 602952

641392
type: SpeciesReference
stoichiometry: 1.0
species: 602976

602976
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: L-Lactaldehyde_C3H6O2

641332
type: SpeciesReference
stoichiometry: 3.0
species: 599469

641428
type: SpeciesReference
stoichiometry: 2.0
species: 599581

641404
type: SpeciesReference
stoichiometry: 3.0
species: 605272

641440
type: SpeciesReference
stoichiometry: 1.0
species: 597783

597783
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Glycolaldehyde_C2H4O2

641356
type: SpeciesReference
stoichiometry: 1.0
species: 598301

641573
type: SpeciesReference
stoichiometry: 3.0
species: 605334

641548
type: SpeciesReference
stoichiometry: 2.0
species: 605394

641320
type: SpeciesReference
stoichiometry: 1.0
species: 598241

641416
type: SpeciesReference
stoichiometry: 2.0
species: 605454

641488
type: SpeciesReference
stoichiometry: 2.0
species: 607510

641476
type: SpeciesReference
stoichiometry: 1.0
species: 598638

598638
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Glycolate_C2H3O3

612596
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: zymosterol intermediate 2_C27H42O

612397
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _7-alpha,24(S)-Dihydroxycholesterol_C27H46O3

588252
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Acetyl-ACP_C13H23N2O8PRS

585779
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Hydroxy-N6,N6,N6-trimethyl-L-lysine_C9H20N2O3

018491
type: Reaction
reactant: 705850
product: 705934
is: ENSECAG00000016157.1
product: 705886
is: http://identifiers.org/ec-code/2.4.1.62
fast: false
reversible: false
product: 705910
product: 705922
product: 705874
reactant: 705838
notes: R_B3GALT42g subsystem: Sphingolipid Metabolism R_B3GALT42g equation: [g] : gm2_hs + udpgal --> gm1_hs + h + udp R_B3GALT41g subsystem: Sphingolipid Metabolism R_B3GALT41g equation: [g] : ga2_hs + udpgal --> ga1_hs + h + udp R_B3GALT43g subsystem: Sphingolipid Metabolism R_B3GALT43g equation: [g] : gd2_hs + udpgal --> gd1b_hs + h + udp R_B3GALT44g subsystem: Sphingolipid Metabolism R_B3GALT44g equation: [g] : gt2_hs + udpgal --> gt1c_hs + h + udp
reactant: 705826
reactant: 705814
reactant: 705862
product: 705898

705850
type: SpeciesReference
stoichiometry: 1.0
species: 598772

598772
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: ganglioside GM2 (homo sapiens)_C49H85N3O25FULLRCO

705934
type: SpeciesReference
stoichiometry: 1.0
species: 597868

705886
type: SpeciesReference
stoichiometry: 4.0
species: 611417

705910
type: SpeciesReference
stoichiometry: 1.0
species: 597336

705922
type: SpeciesReference
stoichiometry: 1.0
species: 599108

599108
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GT1c (homo sapiens)_C77H127N5O46FULLRCO

705874
type: SpeciesReference
stoichiometry: 1.0
species: 598736

705838
type: SpeciesReference
stoichiometry: 1.0
species: 599120

599120
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GT2 (homo sapiens)_C71H117N5O41FULLRCO

705826
type: SpeciesReference
stoichiometry: 1.0
species: 597348

597348
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GA2 (homo sapiens)_C38H69N2O17FULLRCO

705814
type: SpeciesReference
stoichiometry: 1.0
species: 597892

705862
type: SpeciesReference
stoichiometry: 4.0
species: 611574

705898
type: SpeciesReference
stoichiometry: 4.0
species: 599556

610103
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: paclitaxel_C47H31NO14

605696
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C42H70N3O30X

017565
type: Reaction
modifier: 697783
product: 697625
product: 697722
notes: R_FAS180COA subsystem: Fatty acid elongation R_FAS180COA equation: [c] : (3) h + malcoa + (2) nadph + pmtcoa --> co2 + coa + h2o + (2) nadp + stcoa R_FAS140COA subsystem: Fatty acid elongation R_FAS140COA equation: [c] : ddcacoa + (3) h + malcoa + (2) nadph --> co2 + coa + h2o + (2) nadp + tdcoa R_FAS160COA subsystem: Fatty acid elongation R_FAS160COA equation: [c] : (3) h + malcoa + (2) nadph + tdcoa --> co2 + coa + h2o + (2) nadp + pmtcoa R_FAS100COA subsystem: Fatty acid elongation R_FAS100COA equation: [c] : (3) h + malcoa + (2) nadph + occoa --> co2 + coa + dcacoa + h2o + (2) nadp R_KAS8 subsystem: Fatty acid elongation R_KAS8 equation: [c] : accoa + (20) h + (7) malcoa + (14) nadph --> (7) co2 + (8) coa + (6) h2o + hdca + (14) nadp R_MCOATA subsystem: Fatty Acid Metabolism R_MCOATA equation: [c] : ACP + malcoa <==> coa + malACP R_FAS120COA subsystem: Fatty acid elongation R_FAS120COA equation: [c] : dcacoa + (3) h + malcoa + (2) nadph --> co2 + coa + ddcacoa + h2o + (2) nadp R_ACOATA subsystem: Fatty Acid Metabolism R_ACOATA equation: [c] : ACP + accoa <==> acACP + coa R_FAS80COA_L subsystem: Fatty acid elongation R_FAS80COA_L equation: [c] : accoa + (9) h + (3) malcoa + (6) nadph --> (3) co2 + (3) coa + (3) h2o + (6) nadp + occoa
product: 697674
reactant: 697553
modifier: 697771
modifier: 697759
reactant: 697601
reactant: 697589
is: http://identifiers.org/ec-code/2.3.1.39
product: 697662
modifier: 697807
product: 697746
modifier: 697820
product: 697698
reactant: 697577
reactant: 697565
reactant: 697541
product: 697649
is: ENSECAG00000019125.1
reactant: 697613
is: http://identifiers.org/ec-code/2.3.1.38
reactant: 697516
product: 697734
product: 697710
fast: false
is: http://identifiers.org/ec-code/2.3.1.41
product: 697686
is: http://identifiers.org/ec-code/2.3.1.86
reversible: false
modifier: 697795
product: 697637
reactant: 697529

697625
type: SpeciesReference
stoichiometry: 1.0
species: 599749

697722
type: SpeciesReference
stoichiometry: 1.0
species: 606179

606179
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Octanoyl-CoA (n-C8:0CoA)_C29H46N7O17P3S

697674
type: SpeciesReference
stoichiometry: 1.0
species: 593803

697553
type: SpeciesReference
stoichiometry: 1.0
species: 593803

697601
type: SpeciesReference
stoichiometry: 44.0
species: 599531

697589
type: SpeciesReference
stoichiometry: 2.0
species: 588408

697662
type: SpeciesReference
stoichiometry: 1.0
species: 610187

697746
type: SpeciesReference
stoichiometry: 14.0
species: 599421

697698
type: SpeciesReference
stoichiometry: 1.0
species: 609740

609740
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S

697577
type: SpeciesReference
stoichiometry: 1.0
species: 606179

697565
type: SpeciesReference
stoichiometry: 1.0
species: 607558

697541
type: SpeciesReference
stoichiometry: 15.0
species: 604197

697649
type: SpeciesReference
stoichiometry: 16.0
species: 592342

697613
type: SpeciesReference
stoichiometry: 30.0
species: 605442

697516
type: SpeciesReference
stoichiometry: 1.0
species: 594117

594117
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dodecanoyl-CoA (n-C12:0CoA)_C33H54N7O17P3S

697734
type: SpeciesReference
stoichiometry: 15.0
species: 592269

697710
type: SpeciesReference
stoichiometry: 30.0
species: 605370

697686
type: SpeciesReference
stoichiometry: 1.0
species: 607558

697637
type: SpeciesReference
stoichiometry: 1.0
species: 594117

697529
type: SpeciesReference
stoichiometry: 1.0
species: 610187

589920
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: lysophosphatidic acid (homo sapiens)_C3H6O5PFULLRCO2

016124
type: Reaction
reactant: 684379
is: ENSECAG00000023112.1
product: 684487
product: 684403
product: 684439
product: 684451
reactant: 684295
reactant: 684367
reactant: 684283
product: 684391
reactant: 684319
reactant: 684307
product: 684475
reactant: 684331
is: ENSECAG00000015881.1
reversible: false
product: 684427
notes: R_GLCAT9g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT9g equation: [g] : hs_pre7 + udpglcur --> h + hs_pre8 + udp R_GLCAT6g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT6g equation: [g] : hs_pre1 + udpglcur --> h + hs_pre2 + udp R_GLCNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT2g equation: [g] : hs_pre2 + uacgam --> h + hs_pre3 + udp R_GLCAT8g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT8g equation: [g] : hs_pre5 + udpglcur --> h + hs_pre6 + udp R_GLCNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT5g equation: [g] : hs_pre8 + uacgam --> h + hs_pre9 + udp R_GLCNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT3g equation: [g] : hs_pre4 + uacgam --> h + hs_pre5 + udp R_GLCAT7g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT7g equation: [g] : hs_pre3 + udpglcur --> h + hs_pre4 + udp R_GLCNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT4g equation: [g] : hs_pre6 + uacgam --> h + hs_pre7 + udp
reactant: 684271
reactant: 684355
reactant: 684343
fast: false
product: 684463
product: 684415
product: 684499

684379
type: SpeciesReference
stoichiometry: 1.0
species: 600719

600719
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: heparan sulfate, precursor 6_C65H96N3O53X

684487
type: SpeciesReference
stoichiometry: 1.0
species: 600683

600683
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: heparan sulfate, precursor 3_C45H69N2O36X

684403
type: SpeciesReference
stoichiometry: 8.0
species: 611417

684439
type: SpeciesReference
stoichiometry: 1.0
species: 600671

684451
type: SpeciesReference
stoichiometry: 1.0
species: 600707

600707
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: heparan sulfate, precursor 5_C59H89N3O47X

684295
type: SpeciesReference
stoichiometry: 1.0
species: 600695

600695
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: heparan sulfate, precursor 4_C51H76N2O42X

684367
type: SpeciesReference
stoichiometry: 1.0
species: 600683

684283
type: SpeciesReference
stoichiometry: 4.0
species: 611381

684391
type: SpeciesReference
stoichiometry: 1.0
species: 600755

600755
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: heparan sulfate, precursor 9_C87H129N5O69X

684319
type: SpeciesReference
stoichiometry: 1.0
species: 600671

684307
type: SpeciesReference
stoichiometry: 4.0
species: 611598

611598
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: UDP-D-glucuronate_C15H19N2O18P2

684475
type: SpeciesReference
stoichiometry: 1.0
species: 600731

684331
type: SpeciesReference
stoichiometry: 1.0
species: 600707

684427
type: SpeciesReference
stoichiometry: 1.0
species: 600695

684271
type: SpeciesReference
stoichiometry: 1.0
species: 600659

600659
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: heparan sulfate, precursor 1_C31H49NO25X

684355
type: SpeciesReference
stoichiometry: 1.0
species: 600731

684343
type: SpeciesReference
stoichiometry: 1.0
species: 600743

600743
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: heparan sulfate, precursor 8_C79H116N4O64X

684463
type: SpeciesReference
stoichiometry: 1.0
species: 600743

684415
type: SpeciesReference
stoichiometry: 8.0
species: 599556

684499
type: SpeciesReference
stoichiometry: 1.0
species: 600719

595351
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: disialyl-T antigen_C36H56N3O26X

593900
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: dCMP_C9H12N3O7P

592208
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: CMP-N-acetylneuraminate_C20H29N4O16P

598277
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: L-Glutamate_C5H8NO4

011354
type: Reaction
fast: false
product: 637539
notes: R_PIter subsystem: Transport, Endoplasmic Reticular R_PIter equation: pi[r] <==> pi[c] R_G6Pter subsystem: Transport, Endoplasmic Reticular R_G6Pter equation: g6p[c] <==> g6p[r]
reversible: true
reactant: 637515
product: 637551
reactant: 637527
is: ENSECAG00000006892.1

637539
type: SpeciesReference
stoichiometry: 1.0
species: 607462

637515
type: SpeciesReference
stoichiometry: 1.0
species: 607534

637551
type: SpeciesReference
stoichiometry: 1.0
species: 597324

637527
type: SpeciesReference
stoichiometry: 1.0
species: 597312

597312
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Glucose 6-phosphate_C6H11O9P

008981
type: Reaction
reactant: 616541
notes: R_MDHm subsystem: Citric Acid Cycle R_MDHm equation: [m] : mal-L + nad <==> h + nadh + oaa R_SLDxm subsystem: Cysteine Metabolism R_SLDxm equation: [m] : nad + sl-L <==> 3spyr + h + nadh
fast: false
is: ENSECAG00000005660.1
product: 616553
is: http://identifiers.org/ec-code/1.1.1.272
product: 616590
product: 616565
reversible: true
reactant: 616529
reactant: 616516
product: 616578
is: http://identifiers.org/ec-code/1.1.1.37

616541
type: SpeciesReference
stoichiometry: 1.0
species: 604185

616553
type: SpeciesReference
stoichiometry: 1.0
species: 586144

616590
type: SpeciesReference
stoichiometry: 2.0
species: 605334

616565
type: SpeciesReference
stoichiometry: 1.0
species: 606106

616529
type: SpeciesReference
stoichiometry: 2.0
species: 605272

616516
type: SpeciesReference
stoichiometry: 1.0
species: 609436

616578
type: SpeciesReference
stoichiometry: 2.0
species: 599581

017841
type: Reaction
product: 699889
reactant: 699817
reactant: 699829
product: 699865
fast: false
notes: R_GLXO2p subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO2p equation: [x] : glx + h2o + o2 --> h + h2o2 + oxa R_GLYCTO1p subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLYCTO1p equation: [x] : glyclt + o2 --> glx + h2o2
reversible: false
product: 699901
reactant: 699853
is: ENSECAG00000010314.1
reactant: 699841
product: 699877
is: ENSECAG00000018493.1

699889
type: SpeciesReference
stoichiometry: 1.0
species: 606552

606552
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Oxalate_C2O4

699817
type: SpeciesReference
stoichiometry: 1.0
species: 598650

598650
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Glycolate_C2H3O3

699829
type: SpeciesReference
stoichiometry: 1.0
species: 599506

699865
type: SpeciesReference
stoichiometry: 2.0
species: 599409

699901
type: SpeciesReference
stoichiometry: 1.0
species: 599617

699853
type: SpeciesReference
stoichiometry: 1.0
species: 598434

699841
type: SpeciesReference
stoichiometry: 2.0
species: 606021

699877
type: SpeciesReference
stoichiometry: 1.0
species: 598434

607426
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: phytanic acid_C20H39O2

595072
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Deamino-NAD+_C21H24N6O15P2

017505
type: Reaction
product: 697167
product: 697179
is: http://identifiers.org/ec-code/2.6.1.42
product: 697203
reactant: 697155
fast: false
is: http://identifiers.org/ec-code/2.6.1.6
product: 697191
reactant: 697143
notes: R_ILETA subsystem: Valine, Leucine, and Isoleucine Metabolism R_ILETA equation: [c] : akg + ile-L <==> 3mop + glu-L R_VALTA subsystem: Valine, Leucine, and Isoleucine Metabolism R_VALTA equation: [c] : akg + val-L <==> 3mob + glu-L R_LEUTA subsystem: Valine, Leucine, and Isoleucine Metabolism R_LEUTA equation: [c] : akg + leu-L <==> 4mop + glu-L
reversible: true
reactant: 697131
is: ENSECAG00000020973.1
reactant: 697119

697167
type: SpeciesReference
stoichiometry: 1.0
species: 585889

585889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _3-Methyl-2-oxobutanoate_C5H7O3

697179
type: SpeciesReference
stoichiometry: 1.0
species: 585914

585914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: (S)-3-Methyl-2-oxopentanoate_C6H9O3

697203
type: SpeciesReference
stoichiometry: 1.0
species: 586484

697155
type: SpeciesReference
stoichiometry: 1.0
species: 603048

697191
type: SpeciesReference
stoichiometry: 3.0
species: 598265

697143
type: SpeciesReference
stoichiometry: 1.0
species: 601032

697131
type: SpeciesReference
stoichiometry: 1.0
species: 612010

697119
type: SpeciesReference
stoichiometry: 3.0
species: 589688

010448
type: Reaction
notes: R_THRt4 subsystem: Transport, Extracellular R_THRt4 equation: na1[e] + thr-L[e] --> na1[c] + thr-L[c] R_HISt4 subsystem: Transport, Extracellular R_HISt4 equation: his-L[e] + na1[e] --> his-L[c] + na1[c] R_SERt4 subsystem: Transport, Extracellular R_SERt4 equation: na1[e] + ser-L[e] --> na1[c] + ser-L[c] R_ALAt4 subsystem: Transport, Extracellular R_ALAt4 equation: ala-L[e] + na1[e] --> ala-L[c] + na1[c] R_PROt4 subsystem: Transport, Extracellular R_PROt4 equation: na1[e] + pro-L[e] --> na1[c] + pro-L[c] R_ASNt4 subsystem: Transport, Extracellular R_ASNt4 equation: asn-L[e] + na1[e] --> asn-L[c] + na1[c] R_METt4 subsystem: Transport, Extracellular R_METt4 equation: met-L[e] + na1[e] --> met-L[c] + na1[c] R_GLYt4 subsystem: Transport, Extracellular R_GLYt4 equation: gly[e] + na1[e] --> gly[c] + na1[c] R_PHEt4 subsystem: Transport, Extracellular R_PHEt4 equation: na1[e] + phe-L[e] --> na1[c] + phe-L[c] R_GLNt4 subsystem: Transport, Extracellular R_GLNt4 equation: gln-L[e] + na1[e] --> gln-L[c] + na1[c]
reactant: 629992
fast: false
reactant: 629944
product: 630016
product: 630101
reactant: 629895
product: 630028
product: 630113
reactant: 629919
product: 630077
product: 630065
reactant: 629956
reactant: 629931
reversible: false
product: 630053
product: 630041
product: 630125
reactant: 629980
reactant: 629883
reactant: 629968
product: 630137
reactant: 630004
reactant: 629907
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is: ENSECAG00000014498.1

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630028
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630077
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630065
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629956
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species: 598458

629931
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species: 605200

630053
type: SpeciesReference
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species: 600025

630041
type: SpeciesReference
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species: 598205

630125
type: SpeciesReference
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species: 607292

629980
type: SpeciesReference
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species: 598217

629883
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species: 600037

629968
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species: 610764

630137
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species: 608138

630004
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629907
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species: 590631

630089
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species: 604560

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015751
type: Reaction
is: http://identifiers.org/ec-code/2.4.1.130
product: 680431
fast: false
is: ENSECAG00000024102.1
product: 680455
notes: R_DOLPMT3_Uer subsystem: N-Glycan Biosynthesis R_DOLPMT3_Uer equation: [r] : (0.1) dolmanp_U + (0.1) m6mpdol_U --> (0.1) dolp_U + h + (0.1) m7mpdol_U R_DOLPMT3_Ler subsystem: N-Glycan Biosynthesis R_DOLPMT3_Ler equation: [r] : (0.1) dolmanp_L + (0.1) m6mpdol_L --> (0.1) dolp_L + h + (0.1) m7mpdol_L
product: 680443
reactant: 680382
reactant: 680395
reactant: 680407
product: 680480
reversible: false
product: 680467
reactant: 680419

680431
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species: 595230

680455
type: SpeciesReference
stoichiometry: 1.0
species: 595254

680443
type: SpeciesReference
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species: 604025

680382
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species: 603962

603962
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: (alpha-D-Mannosyl)6-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1605H2640N20O520P20

680395
type: SpeciesReference
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species: 595206

680407
type: SpeciesReference
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species: 603950

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type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: (alpha-D-Mannosyl)6-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1660H2728N20O520P20

680480
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species: 599605

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species: 604038

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type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: (alpha-D-Mannosyl)7-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1665H2740N20O570P20

680419
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species: 595181

612449
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
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name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane_C27H48O3

609995
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
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in compartment: 584401

593668
type: Species
constant: false
boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: dADP_C10H12N5O9P2

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type: Species
constant: false
boundary condition: false
has only substance units: false
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name: _12 hydroxy arachidonic acid_C20H31O3

598663
type: Species
constant: false
boundary condition: false
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name: glycogen, structure 1 (glycogenin-11[1,4-Glc])_C66H111O56X

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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: chondroitin sulfate C (GalNAc6S-GlcA), free chain_C45H67N2O46S3

016745
type: Reaction
fast: false
notes: R_PSP_L subsystem: Glycine, Serine, and Threonine Metabolism R_PSP_L equation: [c] : h2o + pser-L --> pi + ser-L
product: 689889
name: phosphoserine phosphatase (L-serine)
is: http://identifiers.org/ec-code/3.1.3.3
is: ENSECAG00000020880.1
reactant: 689865
product: 689877
reactant: 689853
reversible: false

689889
type: SpeciesReference
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species: 607462

689865
type: SpeciesReference
stoichiometry: 1.0
species: 599421

689877
type: SpeciesReference
stoichiometry: 1.0
species: 609352

689853
type: SpeciesReference
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species: 608441

018983
type: Reaction
modifier: 712212
modifier: 712140
product: 712128
is: http://identifiers.org/ec-code/1.2.3.5
is: ENSECAG00000009898.1
notes: R_LDH_L subsystem: Glycolysis/Gluconeogenesis R_LDH_L equation: [c] : lac-L + nad <==> h + nadh + pyr R_MCLOR subsystem: Cysteine Metabolism R_MCLOR equation: [c] : mercplac + nad <==> h + mercppyr + nadh R_2HBO subsystem: Propanoate Metabolism R_2HBO equation: [c] : 2hb + nad <==> 2obut + h + nadh R_GLXO1 subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO1 equation: [c] : glx + h2o + nad --> (2) h + nadh + oxa
modifier: 712176
fast: false
product: 712103
reactant: 712079
modifier: 712224
modifier: 712188
is: http://identifiers.org/ec-code/1.1.1.27
reactant: 712091
modifier: 712152
modifier: 712164
product: 712116
reactant: 712067
modifier: 712236
reversible: false
modifier: 712200

712128
type: SpeciesReference
stoichiometry: 1.0
species: 605322

712103
type: SpeciesReference
stoichiometry: 1.0
species: 606528

712079
type: SpeciesReference
stoichiometry: 1.0
species: 598410

712091
type: SpeciesReference
stoichiometry: 1.0
species: 599421

712116
type: SpeciesReference
stoichiometry: 2.0
species: 599531

712067
type: SpeciesReference
stoichiometry: 1.0
species: 605248

015451
type: Reaction
product: 676252
reactant: 676132
product: 676288
product: 676276
reactant: 676216
product: 676240
is: ENSECAG00000013128.1
product: 676336
product: 676324
product: 676264
reactant: 676119
reactant: 676180
reversible: false
product: 676312
product: 676300
reactant: 676168
is: http://identifiers.org/ec-code/3.1.3.5
fast: false
reactant: 676192
notes: R_NTD7l subsystem: Nucleic acid degradation R_NTD7l equation: [l] : amp + h2o --> adn + pi R_NTD9l subsystem: Nucleic acid degradation R_NTD9l equation: [l] : gmp + h2o --> gsn + pi R_NTD4l subsystem: Nucleic acid degradation R_NTD4l equation: [l] : cmp + h2o --> cytd + pi R_NTD3l subsystem: Nucleic acid degradation R_NTD3l equation: [l] : dcmp + h2o --> dcyt + pi R_NTD8l subsystem: Nucleic acid degradation R_NTD8l equation: [l] : dgmp + h2o --> dgsn + pi R_NTD2l subsystem: Nucleic acid degradation R_NTD2l equation: [l] : h2o + ump --> pi + uri R_LAPCOAl subsystem: CoA Catabolism R_LAPCOAl equation: [l] : coa + h2o --> dpcoa + pi R_NTD5l subsystem: Nucleic acid degradation R_NTD5l equation: [l] : dtmp + h2o --> pi + thymd R_3NTD7l subsystem: Nucleic acid degradation R_3NTD7l equation: [l] : 3amp + h2o --> adn + pi R_NTD6l subsystem: Nucleic acid degradation R_NTD6l equation: [l] : damp + h2o --> dad-2 + pi
reactant: 676144
reactant: 676107
reactant: 676095
product: 676228
reactant: 676204
reactant: 676156

676252
type: SpeciesReference
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species: 593644

593644
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Deoxyadenosine_C10H13N5O3

676132
type: SpeciesReference
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species: 593900

676288
type: SpeciesReference
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species: 593584

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type: SpeciesReference
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species: 595327

595327
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
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in compartment: 584389
name: Dephospho-CoA_C21H33N7O13P2S

676216
type: SpeciesReference
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species: 593754

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type: SpeciesReference
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species: 594324

594324
type: Species
constant: false
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has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Deoxyguanosine_C10H13N5O4

676336
type: SpeciesReference
stoichiometry: 1.0
species: 610824

676324
type: SpeciesReference
stoichiometry: 2.0
species: 589170

676264
type: SpeciesReference
stoichiometry: 1.0
species: 611865

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type: SpeciesReference
stoichiometry: 1.0
species: 611696

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type: SpeciesReference
stoichiometry: 1.0
species: 592366

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type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Coenzyme A_C21H32N7O16P3S

676312
type: SpeciesReference
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species: 599048

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type: SpeciesReference
stoichiometry: 1.0
species: 594044

594044
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Deoxycytidine_C9H13N3O4

676168
type: SpeciesReference
stoichiometry: 10.0
species: 599457

676192
type: SpeciesReference
stoichiometry: 1.0
species: 595450

595450
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: dTMP_C10H13N2O8P

676144
type: SpeciesReference
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species: 598844

598844
type: Species
constant: false
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initial concentration: NaN
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name: GMP_C10H12N5O8P

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type: SpeciesReference
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species: 590077

590077
type: Species
constant: false
boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: AMP_C10H12N5O7P

676095
type: SpeciesReference
stoichiometry: 1.0
species: 592184

676228
type: SpeciesReference
stoichiometry: 10.0
species: 607498

676204
type: SpeciesReference
stoichiometry: 1.0
species: 585561

585561
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: _3'-AMP_C10H12N5O7P

676156
type: SpeciesReference
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species: 594275

594275
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: dGMP_C10H12N5O7P

589773
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: beta-Alanine_C3H7NO2

606443
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: naphthalene epoxide_C10H8O

012584
type: Reaction
reactant: 648435
product: 648459
product: 648495
is: ENSECAG00000017012.1
notes: R_PI345P3Pn subsystem: Inositol Phosphate Metabolism R_PI345P3Pn equation: [n] : h2o + pail345p_hs --> pail45p_hs + pi R_PI345P3P subsystem: Inositol Phosphate Metabolism R_PI345P3P equation: [c] : h2o + pail345p_hs --> pail45p_hs + pi
reactant: 648411
product: 648471
is: http://identifiers.org/ec-code/3.1.3.67
fast: false
reactant: 648447
reversible: false
product: 648483
reactant: 648423

648435
type: SpeciesReference
stoichiometry: 1.0
species: 599421

648459
type: SpeciesReference
stoichiometry: 1.0
species: 606783

606783
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: phosphatidylinositol 4,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

648495
type: SpeciesReference
stoichiometry: 1.0
species: 607522

607522
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: Phosphate_HO4P

648411
type: SpeciesReference
stoichiometry: 1.0
species: 606673

648471
type: SpeciesReference
stoichiometry: 1.0
species: 607462

648447
type: SpeciesReference
stoichiometry: 1.0
species: 599481

648483
type: SpeciesReference
stoichiometry: 1.0
species: 606771

606771
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: phosphatidylinositol 4,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

648423
type: SpeciesReference
stoichiometry: 1.0
species: 606685

009041
type: Reaction
product: 616988
reactant: 616939
reversible: false
reactant: 616976
notes: R_KHK3 subsystem: Galactose metabolism R_KHK3 equation: [c] : atp + tagat-D --> adp + h + tag1p-D R_KHK2 subsystem: Glyoxylate and Dicarboxylate Metabolism R_KHK2 equation: [c] : atp + xylu-D --> adp + h + xu1p-D R_KHK subsystem: Fructose and Mannose Metabolism R_KHK equation: [c] : atp + fru --> adp + f1p + h
fast: false
product: 617000
reactant: 616951
product: 617024
product: 617036
reactant: 616964
is: http://identifiers.org/ec-code/2.7.1.3
is: ENSECAG00000025017.1
product: 617012

616988
type: SpeciesReference
stoichiometry: 1.0
species: 612512

612512
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Xylulose 1-phosphate_C5H9O8P

616939
type: SpeciesReference
stoichiometry: 1.0
species: 612572

612572
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Xylulose_C5H10O5

616976
type: SpeciesReference
stoichiometry: 1.0
species: 610055

610055
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Tagatose_C6H12O6

617000
type: SpeciesReference
stoichiometry: 1.0
species: 610019

610019
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Tagatose 1-phosphate_C6H11O9P

616951
type: SpeciesReference
stoichiometry: 1.0
species: 596756

617024
type: SpeciesReference
stoichiometry: 1.0
species: 596264

617036
type: SpeciesReference
stoichiometry: 3.0
species: 599531

616964
type: SpeciesReference
stoichiometry: 3.0
species: 590727

617012
type: SpeciesReference
stoichiometry: 3.0
species: 589206

586532
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _4-Methylzymosterol intermediate 1_C29H46O3

018923
type: Reaction
reactant: 711596
product: 711680
reversible: true
reactant: 711608
reactant: 711644
reactant: 711620
product: 711705
product: 711668
fast: false
reactant: 711632
is: http://identifiers.org/ec-code/1.5.1.5
product: 711656
notes: R_MTHFDm subsystem: Folate Metabolism R_MTHFDm equation: [m] : mlthf + nadp <==> methf + nadph R_MTHFCm subsystem: Folate Metabolism R_MTHFCm equation: [m] : h2o + methf <==> 10fthf + h R_MTHFD2m subsystem: Folate Metabolism R_MTHFD2m equation: [m] : mlthf + nad <==> methf + nadh
is: ENSECAG00000017419.1
product: 711692
is: http://identifiers.org/ec-code/3.5.4.9

711596
type: SpeciesReference
stoichiometry: 1.0
species: 604596

604596
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _5,10-Methenyltetrahydrofolate_C20H20N7O6

711680
type: SpeciesReference
stoichiometry: 1.0
species: 605454

711608
type: SpeciesReference
stoichiometry: 1.0
species: 599469

711644
type: SpeciesReference
stoichiometry: 1.0
species: 605394

711620
type: SpeciesReference
stoichiometry: 2.0
species: 604886

711705
type: SpeciesReference
stoichiometry: 1.0
species: 605334

711668
type: SpeciesReference
stoichiometry: 1.0
species: 584617

711632
type: SpeciesReference
stoichiometry: 1.0
species: 605272

711656
type: SpeciesReference
stoichiometry: 2.0
species: 604596

711692
type: SpeciesReference
stoichiometry: 1.0
species: 599581

584894
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: _1 acyl phosphoglycerol_C6H13O7PFULLRCO2

604814
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _1D-myo-Inositol 3,4-bisphosphate_C6H10O12P2

013223
type: Reaction
product: 654065
name: dehydroascorbate reductase
is: ENSECAG00000024613.1
reactant: 654029
fast: false
reversible: false
is: ENSECAG00000015376.1
notes: R_DASCBR subsystem: Ascorbate and Aldarate Metabolism R_DASCBR equation: [c] : dhdascb + h + nadph --> ascb-L + nadp
reactant: 654041
product: 654077
reactant: 654053
is: http://identifiers.org/ec-code/1.6.5.4

654065
type: SpeciesReference
stoichiometry: 1.0
species: 605370

654029
type: SpeciesReference
stoichiometry: 1.0
species: 594528

654041
type: SpeciesReference
stoichiometry: 1.0
species: 599531

654077
type: SpeciesReference
stoichiometry: 1.0
species: 590595

590595
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Ascorbate_C6H8O6

654053
type: SpeciesReference
stoichiometry: 1.0
species: 605442

015847
type: Reaction
reactant: 681735
name: alpha-mannosidase, lysosomal
reversible: false
is: ENSECAG00000022546.1
reactant: 681723
product: 681759
notes: R_A_MANASEly subsystem: N-Glycan Degradation R_A_MANASEly equation: [l] : (2) h2o + m2mn --> (2) man + mn
fast: false
product: 681747
is: http://identifiers.org/ec-code/3.2.1.24

681735
type: SpeciesReference
stoichiometry: 1.0
species: 603770

603770
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: (alpha-D-mannosyl)2-beta-D-mannosyl-N-acetylglucosamine_C26H45NO21

681723
type: SpeciesReference
stoichiometry: 2.0
species: 599457

681759
type: SpeciesReference
stoichiometry: 1.0
species: 604970

604970
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: beta-1,4-mannose-N-acetylglucosamine_C14H25NO11

681747
type: SpeciesReference
stoichiometry: 2.0
species: 604367

604367
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: D-Mannose_C6H12O6

604161
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Malonyl-[acyl-carrier protein]_C14H22N2O10PRS

017060
type: Reaction
reactant: 691941
reactant: 691928
notes: R_ACOX22x subsystem: Bile Acid Biosynthesis R_ACOX22x equation: [x] : dhcholoylcoa + fadh2 + (0.5) o2 --> fad + thcholoylcoa R_ACOX2x subsystem: Bile Acid Biosynthesis R_ACOX2x equation: [x] : cholcoas + fadh2 + o2 --> cholcoads + fad + (2) h2o
reactant: 691965
is: http://identifiers.org/ec-code/1.3.3.6
reactant: 691953
product: 692013
product: 691989
fast: false
reversible: false
product: 692001
product: 691977
is: ENSECAG00000011932.1

691941
type: SpeciesReference
stoichiometry: 1.0
species: 594504

594504
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425

691928
type: SpeciesReference
stoichiometry: 1.5
species: 606021

691965
type: SpeciesReference
stoichiometry: 2.0
species: 596396

596396
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

691953
type: SpeciesReference
stoichiometry: 1.0
species: 591797

692013
type: SpeciesReference
stoichiometry: 1.0
species: 591736

591736
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425

691989
type: SpeciesReference
stoichiometry: 2.0
species: 599506

692001
type: SpeciesReference
stoichiometry: 1.0
species: 610524

691977
type: SpeciesReference
stoichiometry: 2.0
species: 596348

596348
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

607619
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: (R)-Pantothenate_C9H16NO5

592860
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: chondroitin sulfate A (GalNAc4S-GlcA), free chain_C45H67N2O46S3

598085
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: D-glucurono-6,3-lactone_C6H8O6

585125
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _2-Decaprenyl-6-methoxyphenol_C57H88O2

599313
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Guanidinoacetate_C3H7N3O2

012694
type: Reaction
is: http://identifiers.org/ec-code/2.7.7.41
fast: false
is: ENSECAG00000012485.1
product: 649661
reactant: 649613
reactant: 649625
reversible: false
name: phosphatidate cytidylyltransferase
reactant: 649637
notes: R_CDSm subsystem: Glycerophospholipid Metabolism R_CDSm equation: [m] : ctp + h + pa_hs --> cdpdag_hs + ppi
product: 649649

649661
type: SpeciesReference
stoichiometry: 1.0
species: 607740

649613
type: SpeciesReference
stoichiometry: 1.0
species: 606588

649625
type: SpeciesReference
stoichiometry: 1.0
species: 593451

649637
type: SpeciesReference
stoichiometry: 1.0
species: 599581

649649
type: SpeciesReference
stoichiometry: 1.0
species: 591544

591544
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: CDP diacylglycerol (homo sapiens)_C12H17N3O11P2FULLRCO2FULLR2CO2

018310
type: Reaction
name: monoacylglycerol acyltransferase
fast: false
is: ENSECAG00000005838.1
reversible: false
product: 703494
notes: R_MOGAT subsystem: Triacylglycerol Synthesis R_MOGAT equation: [c] : Rtotalcoa + mag_hs --> coa + dag_hs
reactant: 703470
is: ENSECAG00000025135.1
product: 703506
reactant: 703482

703494
type: SpeciesReference
stoichiometry: 1.0
species: 592342

703470
type: SpeciesReference
stoichiometry: 1.0
species: 604125

604125
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: monoacylglycerol 2 (homo sapiens)_C3H7O2FULLR2CO2

703506
type: SpeciesReference
stoichiometry: 1.0
species: 593692

703482
type: SpeciesReference
stoichiometry: 1.0
species: 587997

587997
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: R total Coenzyme A_CO2FULLRC21H31N7O15P3S

595654
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: dUTP_C9H11N2O14P3

611914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: UTP_C9H11N2O15P3

010399
type: Reaction
reactant: 629654
product: 629714
is: ENSECAG00000008097.1
notes: R_CMPSASn subsystem: Aminosugar Metabolism R_CMPSASn equation: [n] : acnam + ctp --> cmpacna + ppi R_CMPSAS subsystem: Aminosugar Metabolism R_CMPSAS equation: [c] : acnam + ctp --> cmpacna + ppi
reactant: 629642
product: 629702
reactant: 629629
reversible: false
is: http://identifiers.org/ec-code/2.7.7.43
reactant: 629666
fast: false
product: 629678
product: 629690

629654
type: SpeciesReference
stoichiometry: 1.0
species: 588953

629714
type: SpeciesReference
stoichiometry: 1.0
species: 607728

629642
type: SpeciesReference
stoichiometry: 1.0
species: 588929

629702
type: SpeciesReference
stoichiometry: 1.0
species: 592233

592233
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: CMP-N-acetylneuraminate_C20H29N4O16P

629629
type: SpeciesReference
stoichiometry: 1.0
species: 593463

629666
type: SpeciesReference
stoichiometry: 1.0
species: 593439

629678
type: SpeciesReference
stoichiometry: 1.0
species: 592208

629690
type: SpeciesReference
stoichiometry: 1.0
species: 607753

607753
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: Diphosphate_HO7P2

017661
type: Reaction
product: 698636
product: 698649
reactant: 698599
is: ENSECAG00000006898.1
notes: R_ACHEe subsystem: Glycerophospholipid Metabolism R_ACHEe equation: [e] : ach + h2o --> ac + chol + h
is: http://identifiers.org/ec-code/3.1.1.7
name: Acetylcholinesterase
reactant: 698611
fast: false
reversible: false
product: 698623

698636
type: SpeciesReference
stoichiometry: 1.0
species: 588276

698649
type: SpeciesReference
stoichiometry: 1.0
species: 591640

698599
type: SpeciesReference
stoichiometry: 1.0
species: 599433

698611
type: SpeciesReference
stoichiometry: 1.0
species: 588832

588832
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Acetylcholine_C7H16NO2

698623
type: SpeciesReference
stoichiometry: 1.0
species: 599544

605175
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: ((N-acetyl-D-glucosaminyl)4-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C66H109N6O45X

589809
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: D-Alanine_C3H7NO2

012101
type: Reaction
reactant: 643860
name: Serine/Lysine Na-dependent exchange (Ser in)
product: 643897
notes: R_SERLYSNaex subsystem: Transport, Extracellular R_SERLYSNaex equation: lys-L[c] + na1[e] + ser-L[e] --> lys-L[e] + na1[c] + ser-L[c]
fast: false
reactant: 643836
reversible: false
product: 643872
is: ENSECAG00000001058.1
reactant: 643848
product: 643884

643860
type: SpeciesReference
stoichiometry: 1.0
species: 609364

643897
type: SpeciesReference
stoichiometry: 1.0
species: 603674

643836
type: SpeciesReference
stoichiometry: 1.0
species: 603662

643872
type: SpeciesReference
stoichiometry: 1.0
species: 609352

643848
type: SpeciesReference
stoichiometry: 1.0
species: 605200

643884
type: SpeciesReference
stoichiometry: 1.0
species: 605187

607765
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Diphosphate_HO7P2

017986
type: Reaction
reactant: 701284
reactant: 701296
reactant: 701008
reactant: 701176
is: http://identifiers.org/ec-code/1.3.99.12
product: 701585
reactant: 701236
is: http://identifiers.org/ec-code/1.3.99.2
reactant: 701128
product: 701392
product: 701537
product: 701525
reactant: 701140
product: 701597
reactant: 701056
is: http://identifiers.org/ec-code/1.3.99.3
product: 701513
reactant: 701200
reactant: 701356
reactant: 701380
product: 701501
reactant: 701260
product: 701573
reactant: 701320
product: 701561
reactant: 701188
reactant: 701212
product: 701417
reactant: 701020
reactant: 701248
reactant: 701152
reactant: 701164
reactant: 701080
is: ENSECAG00000021085.1
reactant: 701368
reactant: 701032
reactant: 701104
product: 701453
product: 701429
reactant: 701068
product: 701489
reversible: false
product: 701405
reactant: 701272
product: 701477
reactant: 701332
notes: R_FAOXC183806m subsystem: Fatty acid oxidation R_FAOXC183806m equation: [m] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC161802m subsystem: Fatty acid activation R_FAOXC161802m equation: [m] : (4) coa + (3) fad + (4) h2o + hdd2coa + (4) nad --> (4) accoa + (3) fadh2 + (4) h + (4) nadh + occoa R_FAOXC160 subsystem: Fatty acid oxidation R_FAOXC160 equation: [m] : (7) coa + (7) fad + (7) h2o + (7) nad + pmtcoa --> (8) accoa + (7) fadh2 + (7) h + (7) nadh R_FAOXC2031836m subsystem: Fatty acid oxidation R_FAOXC2031836m equation: [m] : coa + dlnlcgcoa + fad + h2o + nad --> accoa + fadh2 + h + lnlncgcoa + nadh R_FAOXC80 subsystem: Fatty acid oxidation R_FAOXC80 equation: [m] : (3) coa + (3) fad + (3) h2o + (3) nad + occoa --> (4) accoa + (3) fadh2 + (3) h + (3) nadh R_FAOXC170m subsystem: Fatty acid oxidation R_FAOXC170m equation: [m] : (7) coa + (7) fad + (7) h2o + hpdcacoa + (7) nad --> (7) accoa + (7) fadh2 + (7) h + (7) nadh + ppcoa R_FAOXC11 subsystem: Fatty acid oxidation R_FAOXC11 equation: [m] : coa + dmnoncoa + h2o + nad --> accoa + dmhptcoa + h + nadh R_PPCOAOm subsystem: Propanoate Metabolism R_PPCOAOm equation: [m] : fad + ppcoa --> fadh2 + prpncoa R_FAOXC2251836m subsystem: Fatty acid oxidation R_FAOXC2251836m equation: [m] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_FAOXC18280m subsystem: Fatty acid oxidation R_FAOXC18280m equation: [m] : (5) coa + (3) fad + (5) h2o + lneldccoa + (5) nad --> (5) accoa + (3) fadh2 + (5) h + (5) nadh + occoa R_FAOXC16180m subsystem: Fatty acid oxidation R_FAOXC16180m equation: [m] : (4) coa + (3) fad + (4) h2o + hdcoa + (4) nad --> (4) accoa + (3) fadh2 + (4) h + (4) nadh + occoa R_FAOXC2051843m subsystem: Fatty acid oxidation R_FAOXC2051843m equation: [m] : coa + h2o + nad + tmndnccoa --> accoa + h + nadh + strdnccoa R_FAOXC183803m subsystem: Fatty acid oxidation R_FAOXC183803m equation: [m] : (5) coa + (2) fad + (5) …
product: 701465
fast: false
reactant: 701224
reactant: 700984
reactant: 700996
product: 701441
product: 701549
reactant: 701344
reactant: 701092
reactant: 701308
reactant: 701044
reactant: 701116

701284
type: SpeciesReference
stoichiometry: 1.0
species: 600213

701296
type: SpeciesReference
stoichiometry: 111.0
species: 592378

701008
type: SpeciesReference
stoichiometry: 1.0
species: 606335

701176
type: SpeciesReference
stoichiometry: 1.0
species: 594976

594976
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S

701585
type: SpeciesReference
stoichiometry: 1.0
species: 594952

701236
type: SpeciesReference
stoichiometry: 1.0
species: 608481

701128
type: SpeciesReference
stoichiometry: 1.0
species: 606191

701392
type: SpeciesReference
stoichiometry: 1.0
species: 609752

701537
type: SpeciesReference
stoichiometry: 2.0
species: 610921

701525
type: SpeciesReference
stoichiometry: 3.0
species: 599385

701140
type: SpeciesReference
stoichiometry: 2.0
species: 591210

701597
type: SpeciesReference
stoichiometry: 111.0
species: 605334

701056
type: SpeciesReference
stoichiometry: 111.0
species: 599469

701513
type: SpeciesReference
stoichiometry: 116.0
species: 588432

701200
type: SpeciesReference
stoichiometry: 1.0
species: 599869

701356
type: SpeciesReference
stoichiometry: 78.0
species: 596324

701380
type: SpeciesReference
stoichiometry: 3.0
species: 605984

701501
type: SpeciesReference
stoichiometry: 1.0
species: 585283

701260
type: SpeciesReference
stoichiometry: 1.0
species: 603421

701573
type: SpeciesReference
stoichiometry: 111.0
species: 599581

701320
type: SpeciesReference
stoichiometry: 1.0
species: 610199

701561
type: SpeciesReference
stoichiometry: 2.0
species: 603542

701188
type: SpeciesReference
stoichiometry: 1.0
species: 591088

701212
type: SpeciesReference
stoichiometry: 1.0
species: 603361

701417
type: SpeciesReference
stoichiometry: 1.0
species: 607571

701020
type: SpeciesReference
stoichiometry: 2.0
species: 607571

701248
type: SpeciesReference
stoichiometry: 1.0
species: 611974

701152
type: SpeciesReference
stoichiometry: 1.0
species: 603481

701164
type: SpeciesReference
stoichiometry: 1.0
species: 606359

701080
type: SpeciesReference
stoichiometry: 1.0
species: 595823

701368
type: SpeciesReference
stoichiometry: 111.0
species: 605272

701032
type: SpeciesReference
stoichiometry: 1.0
species: 594880

701104
type: SpeciesReference
stoichiometry: 1.0
species: 585259

701453
type: SpeciesReference
stoichiometry: 2.0
species: 609848

701429
type: SpeciesReference
stoichiometry: 78.0
species: 596372

701068
type: SpeciesReference
stoichiometry: 1.0
species: 609848

701489
type: SpeciesReference
stoichiometry: 1.0
species: 590799

701405
type: SpeciesReference
stoichiometry: 1.0
species: 590487

701272
type: SpeciesReference
stoichiometry: 1.0
species: 607703

701477
type: SpeciesReference
stoichiometry: 11.0
species: 606191

701332
type: SpeciesReference
stoichiometry: 2.0
species: 593948

701465
type: SpeciesReference
stoichiometry: 1.0
species: 608367

701224
type: SpeciesReference
stoichiometry: 1.0
species: 610921

700984
type: SpeciesReference
stoichiometry: 1.0
species: 609752

700996
type: SpeciesReference
stoichiometry: 1.0
species: 590487

701441
type: SpeciesReference
stoichiometry: 1.0
species: 585247

585247
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401

701549
type: SpeciesReference
stoichiometry: 2.0
species: 607703

701344
type: SpeciesReference
stoichiometry: 1.0
species: 603542

701092
type: SpeciesReference
stoichiometry: 1.0
species: 590391

701308
type: SpeciesReference
stoichiometry: 1.0
species: 600888

701044
type: SpeciesReference
stoichiometry: 1.0
species: 599845

701116
type: SpeciesReference
stoichiometry: 1.0
species: 589398

597880
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GD1c (homo sapiens)_C66H111N4O38FULLRCO

606905
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Pantetheine 4'-phosphate_C11H21N2O7PS

011136
type: Reaction
is: ENSECAG00000014562.1
product: 636308
product: 636320
reactant: 636124
reactant: 636188
reactant: 636098
reactant: 636175
reactant: 636212
is: http://identifiers.org/ec-code/2.4.1.152
product: 636248
notes: R_FUT97g subsystem: Blood Group Biosynthesis R_FUT97g equation: [g] : fuc132galacglcgal14acglcgalgluside_hs + gdpfuc --> fucfuc132galacglcgal14acglcgalgluside_hs + gdp + h R_FUT98g subsystem: Blood Group Biosynthesis R_FUT98g equation: [g] : galacglcgal14acglcgalgluside_hs + gdpfuc --> fuc13galacglcgal14acglcgalgluside_hs + gdp + h R_FUT91g subsystem: Blood Group Biosynthesis R_FUT91g equation: [g] : gal14acglcgalgluside_hs + gdpfuc --> fucgal14acglcgalgluside_hs + gdp + h R_FUT910g subsystem: Blood Group Biosynthesis R_FUT910g equation: [g] : fucgalacglc13galacglcgal14acglcgalgluside_hs + gdpfuc --> fucfucgalacglc13galacglcgal14acglcgalgluside_hs + gdp + h R_FUT95g subsystem: Blood Group Biosynthesis R_FUT95g equation: [g] : fucfucgalacglcgal14acglcgalgluside_hs + gdpfuc --> fucfucfucgalacglcgal14acglcgalgluside_hs + gdp + h R_FUT911g subsystem: Blood Group Biosynthesis R_FUT911g equation: [g] : fucfucgalacglc13galacglcgal14acglcgalgluside_hs + gdpfuc --> fucfucfucgalacglc13galacglcgal14acglcgalgluside_hs + gdp + h R_FUT96g subsystem: Blood Group Biosynthesis R_FUT96g equation: [g] : galacglcgal14acglcgalgluside_hs + gdpfuc --> fuc132galacglcgal14acglcgalgluside_hs + gdp + h R_FUT94g subsystem: Blood Group Biosynthesis R_FUT94g equation: [g] : fucgalacglcgal14acglcgalgluside_hs + gdpfuc --> fucfucgalacglcgal14acglcgalgluside_hs + gdp + h R_FUT92g subsystem: Blood Group Biosynthesis R_FUT92g equation: [g] : acngal14acglcgalgluside_hs + gdpfuc --> fucacngal14acglcgalgluside_hs + gdp + h R_FUT93g subsystem: Blood Group Biosynthesis R_FUT93g equation: [g] : fuc12gal14acglcgalgluside_hs + gdpfuc --> fucfuc12gal14acglcgalgluside_hs + gdp + h R_FUT99g subsystem: Blood Group Biosynthesis R_FUT99g equation: [g] : galacglc13galacglcgal14acglcgalgluside_hs + gdpfuc --> fucgalacglc13galacglcgal14acglcgalgluside_hs + gdp + h
reactant: 636151
product: 636236
reactant: 636164
product: 636296
product: 636224
product: 636284
fast: false
reactant: 636085
reactant: 636111
product: 636368
product: 636344
product: 636272
product: 636356
reactant: 636199
reactant: 636137
reversible: false
product: 636332
product: 636260

636308
type: SpeciesReference
stoichiometry: 1.0
species: 596805

596805
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: III3Fuc-nLc6Cer_C64H112N3O36FULLRCO

636320
type: SpeciesReference
stoichiometry: 11.0
species: 597964

597964
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GDP_C10H12N5O11P2

636124
type: SpeciesReference
stoichiometry: 1.0
species: 588977

636188
type: SpeciesReference
stoichiometry: 1.0
species: 596962

596962
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)2 (Cer)1_C84H145N4O50FULLRCO

636098
type: SpeciesReference
stoichiometry: 1.0
species: 596793

596793
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: V3Fuc-nLc6Cer_C64H112N3O36FULLRCO

636175
type: SpeciesReference
stoichiometry: 11.0
species: 598025

636212
type: SpeciesReference
stoichiometry: 2.0
species: 597481

636248
type: SpeciesReference
stoichiometry: 1.0
species: 596889

596889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377

636151
type: SpeciesReference
stoichiometry: 1.0
species: 597059

597059
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: VI2Fuc-nLc6_C64H112N3O36FULLRCO

636236
type: SpeciesReference
stoichiometry: 1.0
species: 596913

596913
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Ley glycolipid_C56H99N2O30FULLRCO

636164
type: SpeciesReference
stoichiometry: 1.0
species: 596781

636296
type: SpeciesReference
stoichiometry: 1.0
species: 596974

596974
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: (Gal)3 (Glc)1 (GlcNAc)2 (LFuc)2 (Cer)1_C70H122N3O40FULLRCO

636224
type: SpeciesReference
stoichiometry: 1.0
species: 596793

636284
type: SpeciesReference
stoichiometry: 11.0
species: 599556

636085
type: SpeciesReference
stoichiometry: 1.0
species: 597384

636111
type: SpeciesReference
stoichiometry: 1.0
species: 597468

636368
type: SpeciesReference
stoichiometry: 1.0
species: 596925

596925
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377

636344
type: SpeciesReference
stoichiometry: 1.0
species: 597047

636272
type: SpeciesReference
stoichiometry: 1.0
species: 597011

597011
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Lacto-N-fucopentaosyl III ceramide_C50H89N2O26FULLRCO

636356
type: SpeciesReference
stoichiometry: 1.0
species: 596950

636199
type: SpeciesReference
stoichiometry: 1.0
species: 597047

636137
type: SpeciesReference
stoichiometry: 1.0
species: 596974

636332
type: SpeciesReference
stoichiometry: 1.0
species: 596962

636260
type: SpeciesReference
stoichiometry: 1.0
species: 596937

594384
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dihydroxyacetone_C3H6O3

587647
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: L-Formylkynurenine_C11H12N2O4

612119
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: omega hydroxy tetradecanoate (n-C14:0)_C14H27O3

609665
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Sphingosine 1-phosphate_C18H37NO5P

612252
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al_C27H46O3

592559
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: Creatine_C4H9N3O2

608567
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Pyridoxamine_C8H13N2O2

586508
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _4-Methylpentanal_C6H12O

018190
type: Reaction
reversible: false
product: 702688
reactant: 702664
fast: false
notes: R_GLYOX subsystem: Pyruvate Metabolism R_GLYOX equation: [c] : h2o + lgt-S --> gthrd + h + lac-D
product: 702700
is: ENSECAG00000006582.1
name: hydroxyacylglutathione hydrolase
is: http://identifiers.org/ec-code/3.1.2.6
reactant: 702652
product: 702676

702688
type: SpeciesReference
stoichiometry: 1.0
species: 602868

702664
type: SpeciesReference
stoichiometry: 1.0
species: 599421

702700
type: SpeciesReference
stoichiometry: 1.0
species: 599531

702652
type: SpeciesReference
stoichiometry: 1.0
species: 603276

702676
type: SpeciesReference
stoichiometry: 1.0
species: 599192

601840
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: keratan sulfate I, degradation product 5_C222H356N15O194S11

589968
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _2-Aminomuconate 6-semialdehyde_C6H7NO3

008644
type: Reaction
is: ENSECAG00000008767.1
product: 613648
notes: R_LTA4H subsystem: Eicosanoid Metabolism R_LTA4H equation: [c] : h2o + leuktrA4 --> leuktrB4
fast: false
reactant: 613624
reactant: 613636
is: http://identifiers.org/ec-code/3.3.2.6
reversible: false
name: Leukotriene A-4 hydrolase

613648
type: SpeciesReference
stoichiometry: 1.0
species: 603108

603108
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Leukotriene B4_C20H31O4

613624
type: SpeciesReference
stoichiometry: 1.0
species: 599421

613636
type: SpeciesReference
stoichiometry: 1.0
species: 603084

012743
type: Reaction
product: 650578
reactant: 650554
is: ENSECAG00000024423.1
product: 650590
product: 650566
fast: false
reactant: 650542
notes: R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_DHEASt subsystem: Transport, Extracellular R_DHEASt equation: dheas[e] + hco3[c] <==> dheas[c] + hco3[e]
reactant: 650530
reversible: true

650578
type: SpeciesReference
stoichiometry: 1.0
species: 594576

650554
type: SpeciesReference
stoichiometry: 1.0
species: 596138

650590
type: SpeciesReference
stoichiometry: 2.0
species: 599701

650566
type: SpeciesReference
stoichiometry: 1.0
species: 596125

650542
type: SpeciesReference
stoichiometry: 2.0
species: 599689

650530
type: SpeciesReference
stoichiometry: 1.0
species: 594588

589507
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _3alpha-Hydroxy-5beta-androstan-17-one_C19H30O2

013766
type: Reaction
reactant: 660814
reactant: 660851
reactant: 660838
fast: false
product: 660899
reactant: 660826
reversible: true
notes: R_CITRtm subsystem: Transport, Mitochondrial R_CITRtm equation: citr-L[m] <==> citr-L[c] R_ORNt3m subsystem: Transport, Mitochondrial R_ORNt3m equation: h[c] + orn[m] <==> h[m] + orn[c] R_ARGtm subsystem: Transport, Mitochondrial R_ARGtm equation: arg-L[c] + h[m] <==> arg-L[m] + h[c] R_ORNt4m subsystem: Transport, Mitochondrial R_ORNt4m equation: citr-L[c] + h[c] + orn[m] <==> citr-L[m] + h[m] + orn[c] R_LYStm subsystem: Transport, Mitochondrial R_LYStm equation: h[m] + lys-L[c] <==> h[c] + lys-L[m]
reactant: 660790
is: ENSECAG00000007666.1
product: 660887
is: ENSECAG00000005542.1
product: 660938
product: 660951
product: 660912
reactant: 660802
product: 660925
product: 660875
reactant: 660863

660814
type: SpeciesReference
stoichiometry: 1.0
species: 592002

660851
type: SpeciesReference
stoichiometry: 2.0
species: 599581

660838
type: SpeciesReference
stoichiometry: 1.0
species: 592015

660899
type: SpeciesReference
stoichiometry: 1.0
species: 590571

660826
type: SpeciesReference
stoichiometry: 1.0
species: 590547

660790
type: SpeciesReference
stoichiometry: 2.0
species: 606491

660887
type: SpeciesReference
stoichiometry: 1.0
species: 592002

660938
type: SpeciesReference
stoichiometry: 2.0
species: 599531

660951
type: SpeciesReference
stoichiometry: 2.0
species: 599581

660912
type: SpeciesReference
stoichiometry: 2.0
species: 606467

660802
type: SpeciesReference
stoichiometry: 1.0
species: 603662

660925
type: SpeciesReference
stoichiometry: 1.0
species: 592015

660875
type: SpeciesReference
stoichiometry: 1.0
species: 603686

660863
type: SpeciesReference
stoichiometry: 2.0
species: 599531

588154
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Tn antigen_C8H14NO5X

590126
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: androstanedione_C19H28O2

017901
type: Reaction
product: 700202
notes: R_PSSA2_hs subsystem: Glycerophospholipid Metabolism R_PSSA2_hs equation: [c] : pe_hs + ser-L <==> etha + ps_hs
fast: false
reactant: 700166
product: 700190
is: http://identifiers.org/ec-code/2.7.8.8
reactant: 700178
name: Phosphatidylserine synthase homo sapiens
is: ENSECAG00000021925.1
reversible: true

700202
type: SpeciesReference
stoichiometry: 1.0
species: 608404

700166
type: SpeciesReference
stoichiometry: 1.0
species: 609352

700190
type: SpeciesReference
stoichiometry: 1.0
species: 596187

700178
type: SpeciesReference
stoichiometry: 1.0
species: 607110

610427
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: tetracosatetraenoyl coenzyme A_C45H70N7O17P3S

585974
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: _3-Oxodecanoyl-CoA_C31H48N7O18P3S

588288
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Acetate_C2H3O2

606046
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Superoxide anion_O2

593936
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: docosa-4,7,10,13,16-pentaenoyl coenzyme A_C43H64N7O17P3S

603409
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: linoleic coenzyme A_C39H62N7O17P3S

008945
type: Reaction
product: 616310
is: http://identifiers.org/ec-code/3.3.1.1
reactant: 616285
product: 616298
name: Se-Adenosylselenohomocysteine hydrolase
fast: false
is: ENSECAG00000014138.1
reversible: false
notes: R_SEAHCYSHYD subsystem: Selenoamino acid metabolism R_SEAHCYSHYD equation: [c] : h2o + seahcys --> adn + selhcys
reactant: 616273

616310
type: SpeciesReference
stoichiometry: 1.0
species: 589146

616285
type: SpeciesReference
stoichiometry: 1.0
species: 599421

616298
type: SpeciesReference
stoichiometry: 1.0
species: 609280

616273
type: SpeciesReference
stoichiometry: 1.0
species: 609184

013876
type: Reaction
reversible: false
is: ENSECAG00000009002.1
reactant: 661557
fast: false
is: http://identifiers.org/ec-code/2.4.2.19
reactant: 661545
product: 661569
name: nicotinate-nucleotide diphosphorylase (carboxylating)
product: 661593
notes: R_NNDPR subsystem: NAD Metabolism R_NNDPR equation: [c] : (2) h + prpp + quln --> co2 + nicrnt + ppi
product: 661581
reactant: 661533

661557
type: SpeciesReference
stoichiometry: 1.0
species: 608738

608738
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Quinolinate_C7H3NO4

661545
type: SpeciesReference
stoichiometry: 2.0
species: 599531

661569
type: SpeciesReference
stoichiometry: 1.0
species: 605648

661593
type: SpeciesReference
stoichiometry: 1.0
species: 607728

661581
type: SpeciesReference
stoichiometry: 1.0
species: 592269

661533
type: SpeciesReference
stoichiometry: 1.0
species: 608391

608391
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _5-Phospho-alpha-D-ribose 1-diphosphate_C5H8O14P3

017613
type: Reaction
product: 698248
reactant: 698222
reversible: false
is: http://identifiers.org/ec-code/2.4.1.212
product: 698285
fast: false
notes: R_HAS1 subsystem: Hyaluronan Metabolism R_HAS1 equation: uacgam[c] + udpglcur[c] --> (2) h[c] + ha_pre1[e] + (2) udp[c] R_HAS2 subsystem: Hyaluronan Metabolism R_HAS2 equation: ha_pre1[e] + uacgam[c] + udpglcur[c] --> (2) h[c] + ha[e] + (2) udp[c]
product: 698261
is: ENSECAG00000023305.1
reactant: 698235
product: 698273
is: ENSECAG00000021206.1
reactant: 698209

698248
type: SpeciesReference
stoichiometry: 1.0
species: 599665

698222
type: SpeciesReference
stoichiometry: 2.0
species: 611369

698285
type: SpeciesReference
stoichiometry: 4.0
species: 599531

698261
type: SpeciesReference
stoichiometry: 1.0
species: 599641

599641
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: hyaluronan_C28H40N2O22

698235
type: SpeciesReference
stoichiometry: 2.0
species: 611586

698273
type: SpeciesReference
stoichiometry: 4.0
species: 611393

698209
type: SpeciesReference
stoichiometry: 1.0
species: 599665

015319
type: Reaction
product: 674965
product: 674941
reactant: 674584
notes: R_VLCSp subsystem: Bile Acid Biosynthesis R_VLCSp equation: [x] : atp + coa + thcholstoic --> amp + cholcoar + ppi R_VLCS2p subsystem: Bile Acid Biosynthesis R_VLCS2p equation: [x] : atp + coa + dhcholestanate --> amp + dhcholestancoa + ppi R_FATP9t subsystem: Transport, Extracellular R_FATP9t equation: na1[c] + nrvnc[c] <==> na1[e] + nrvnc[e] R_FATP7t subsystem: Transport, Extracellular R_FATP7t equation: crvnc[c] + na1[c] <==> crvnc[e] + na1[e] R_FACOAL191 subsystem: Fatty acid activation R_FACOAL191 equation: [c] : atp + coa + prist --> amp + ppi + pristcoa R_FACOAL206 subsystem: Fatty acid activation R_FACOAL206 equation: [c] : atp + coa + phyt <==> amp + phytcoa + ppi R_VLCSr subsystem: Bile Acid Biosynthesis R_VLCSr equation: [r] : atp + coa + thcholstoic --> amp + cholcoar + ppi R_CYTDt4 subsystem: Transport, Extracellular R_CYTDt4 equation: cytd[e] + na1[e] --> cytd[c] + na1[c] R_FATP6t subsystem: Transport, Extracellular R_FATP6t equation: adrn[c] + na1[c] <==> adrn[e] + na1[e] R_FATP8t subsystem: Transport, Extracellular R_FATP8t equation: lgnc[c] + na1[c] <==> lgnc[e] + na1[e] R_ADNt4 subsystem: Transport, Extracellular R_ADNt4 equation: adn[e] + na1[e] --> adn[c] + na1[c] R_URIt4 subsystem: Transport, Extracellular R_URIt4 equation: na1[e] + uri[e] --> na1[c] + uri[c] R_THMDt4 subsystem: Transport, Extracellular R_THMDt4 equation: na1[e] + thymd[e] --> na1[c] + thymd[c] R_VLCS2r subsystem: Bile Acid Biosynthesis R_VLCS2r equation: [r] : atp + coa + dhcholestanate --> amp + dhcholestancoa + ppi
is: ENSECAG00000007499.1
is: ENSECAG00000011327.1
modifier: 675013
is: http://identifiers.org/ec-code/6.2.1.7
reactant: 674596
fast: false
modifier: 675073
modifier: 675025
product: 674809
reactant: 674659
modifier: 675049
reactant: 674709
is: http://identifiers.org/ec-code/6.2.1.3
is: ENSECAG00000009881.1
reactant: 674683
product: 674881
reactant: 674621
modifier: 675158
product: 674845
reversible: false
product: 674821
product: 674833
reactant: 674748
modifier: 675122
reactant: 674761
reactant: 674608
product: 674917
reactant: 674722
modifier: 675037
modifier: 674977
product: 674893
product: 674869
modifier: 675098
reactant: 674646
modifier: 674989
product: 674857
modifier: 675001
modifier: 675061
modifier: 675110
product: 674929
is: ENSECAG00000020734.1
product: 674905
modifier: 675134
modifier: 675085
reactant: 674735
product: 674797
reactant: 674773
product: 674785
reactant: 674671
reactant: 674696
modifier: 675146
product: 674953
reactant: 674634

674965
type: SpeciesReference
stoichiometry: 1.0
species: 607728

674941
type: SpeciesReference
stoichiometry: 2.0
species: 590102

590102
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: AMP_C10H12N5O7P

674584
type: SpeciesReference
stoichiometry: 1.0
species: 592342

674596
type: SpeciesReference
stoichiometry: 1.0
species: 610572

592740
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: cervonic acid, C22:6 n-3_C22H31O2

674809
type: SpeciesReference
stoichiometry: 2.0
species: 590114

590114
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: AMP_C10H12N5O7P

674659
type: SpeciesReference
stoichiometry: 2.0
species: 592402

674709
type: SpeciesReference
stoichiometry: 1.0
species: 611853

674683
type: SpeciesReference
stoichiometry: 4.0
species: 605200

674881
type: SpeciesReference
stoichiometry: 2.0
species: 607777

674621
type: SpeciesReference
stoichiometry: 1.0
species: 594444

594444
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _3alpha,7alpha-Dihydroxy-5beta-cholestanate_C27H45O4

674845
type: SpeciesReference
stoichiometry: 1.0
species: 593560

674821
type: SpeciesReference
stoichiometry: 1.0
species: 594468

674833
type: SpeciesReference
stoichiometry: 1.0
species: 608066

674748
type: SpeciesReference
stoichiometry: 1.0
species: 593572

589350
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: adrenic acid_C22H35O2

674761
type: SpeciesReference
stoichiometry: 1.0
species: 589158

674608
type: SpeciesReference
stoichiometry: 1.0
species: 610560

610560
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate_C27H45O5

674917
type: SpeciesReference
stoichiometry: 1.0
species: 611841

674722
type: SpeciesReference
stoichiometry: 1.0
species: 608018

607413
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: phytanic acid_C20H39O2

605864
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: nervonic acid_C24H45O2

674893
type: SpeciesReference
stoichiometry: 1.0
species: 589146

674869
type: SpeciesReference
stoichiometry: 1.0
species: 610800

674646
type: SpeciesReference
stoichiometry: 2.0
species: 592414

674857
type: SpeciesReference
stoichiometry: 4.0
species: 605187

603204
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: lignoceric acid_C24H47O2

674929
type: SpeciesReference
stoichiometry: 1.0
species: 591761

591761
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353

674905
type: SpeciesReference
stoichiometry: 1.0
species: 594480

674735
type: SpeciesReference
stoichiometry: 1.0
species: 610812

610812
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Thymidine_C10H14N2O5

674797
type: SpeciesReference
stoichiometry: 2.0
species: 607765

674773
type: SpeciesReference
stoichiometry: 2.0
species: 590775

674785
type: SpeciesReference
stoichiometry: 1.0
species: 591773

591773
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425

674671
type: SpeciesReference
stoichiometry: 1.0
species: 590727

674696
type: SpeciesReference
stoichiometry: 2.0
species: 590787

592728
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: cervonic acid, C22:6 n-3_C22H31O2

674953
type: SpeciesReference
stoichiometry: 1.0
species: 590041

674634
type: SpeciesReference
stoichiometry: 1.0
species: 594456

010954
type: Reaction
reactant: 634850
product: 634910
notes: R_P4503A5 subsystem: CYP Metabolism R_P4503A5 equation: [c] : aflatoxin + h + nadph + o2 --> eaflatoxin + h2o + nadp
product: 634886
reactant: 634862
is: ENSECAG00000023866.1
is: ENSECAG00000019724.1
product: 634898
fast: false
is: ENSECAG00000008604.1
is: ENSECAG00000010734.1
is: ENSECAG00000022630.1
name: cytochrome P450 3A5
reactant: 634874
is: ENSECAG00000016004.1
reactant: 634838
is: ENSECAG00000024477.1
reversible: false

634850
type: SpeciesReference
stoichiometry: 1.0
species: 605960

634910
type: SpeciesReference
stoichiometry: 1.0
species: 599421

634886
type: SpeciesReference
stoichiometry: 1.0
species: 595726

595726
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _8,9 epxoy aflatoxin B1_C17H12O7

634862
type: SpeciesReference
stoichiometry: 1.0
species: 599531

634898
type: SpeciesReference
stoichiometry: 1.0
species: 605370

634874
type: SpeciesReference
stoichiometry: 1.0
species: 605442

634838
type: SpeciesReference
stoichiometry: 1.0
species: 589483

589483
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: aflatoxin B1_C17H12O6

597856
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GD1beta (homo sapiens)_C66H111N4O38FULLRCO

593742
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: dAMP_C10H12N5O6P

019079
type: Reaction
product: 713372
reactant: 713312
is: ENSECAG00000023953.1
is: ENSECAG00000000273.1
product: 713336
notes: R_2OXOADOXm subsystem: Lysine Metabolism R_2OXOADOXm equation: [m] : 2oxoadp + coa + nad --> co2 + glutcoa + nadh R_AKGDm subsystem: Citric Acid Cycle R_AKGDm equation: [m] : akg + coa + nad --> co2 + nadh + succoa
is: http://identifiers.org/ec-code/1.2.4.2
product: 713360
reactant: 713324
reversible: false
reactant: 713300
fast: false
reactant: 713288
product: 713348

713372
type: SpeciesReference
stoichiometry: 2.0
species: 605334

713312
type: SpeciesReference
stoichiometry: 1.0
species: 589712

713336
type: SpeciesReference
stoichiometry: 1.0
species: 609957

713360
type: SpeciesReference
stoichiometry: 1.0
species: 598398

713324
type: SpeciesReference
stoichiometry: 2.0
species: 605272

713300
type: SpeciesReference
stoichiometry: 2.0
species: 592378

713288
type: SpeciesReference
stoichiometry: 1.0
species: 585319

713348
type: SpeciesReference
stoichiometry: 2.0
species: 592294

592764
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: chondroitin sulfate A (GalNAc4S-GlcA), B (IdoA2S-GalNAc4S), and E (GalNAc4,6diS-GlcA), precursor 1_C31H47NO31S2X

015523
type: Reaction
product: 677010
reactant: 676998
name: ammonia transport via proton antiport
product: 677022
reactant: 676986
notes: R_NH4t3r subsystem: Transport, Extracellular R_NH4t3r equation: h[e] + nh4[c] <==> h[c] + nh4[e]
reversible: true
fast: false
is: ENSECAG00000013494.1
is: ENSECAG00000015501.1

677010
type: SpeciesReference
stoichiometry: 1.0
species: 605575

605575
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Ammonium_H4N

676998
type: SpeciesReference
stoichiometry: 1.0
species: 605563

677022
type: SpeciesReference
stoichiometry: 1.0
species: 599531

676986
type: SpeciesReference
stoichiometry: 1.0
species: 599544

009113
type: Reaction
reactant: 617544
reactant: 617532
reversible: false
product: 617653
product: 617580
product: 617677
reactant: 617568
is: ENSECAG00000021223.1
reactant: 617556
notes: R_HSD3B3r subsystem: Steroid Metabolism R_HSD3B3r equation: [r] : eandrstrn + h + nadph --> andrstandn + h2o + nadp R_HSD3B2r subsystem: Steroid Metabolism R_HSD3B2r equation: [r] : eandrstrn + h + nadh --> andrstandn + h2o + nad R_HSD3B11r subsystem: Steroid Metabolism R_HSD3B11r equation: [r] : nad + prgnlone --> h + nadh + prgstrn R_HSD3B12r subsystem: Steroid Metabolism R_HSD3B12r equation: [r] : dhea + nad --> andrstndn + h + nadh R_HSD3B13r subsystem: Steroid Metabolism R_HSD3B13r equation: [r] : 17ahprgnlone + nad --> 17ahprgstrn + h + nadh
fast: false
product: 617605
product: 617629
product: 617592
product: 617641
product: 617665
reactant: 617520
reactant: 617496
reactant: 617484
reactant: 617508
product: 617617

617544
type: SpeciesReference
stoichiometry: 2.0
species: 599605

617532
type: SpeciesReference
stoichiometry: 1.0
species: 594564

617653
type: SpeciesReference
stoichiometry: 3.0
species: 599605

617580
type: SpeciesReference
stoichiometry: 2.0
species: 599493

617677
type: SpeciesReference
stoichiometry: 1.0
species: 584846

617568
type: SpeciesReference
stoichiometry: 2.0
species: 595738

595738
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: epiandrosterone_C19H28O3

617556
type: SpeciesReference
stoichiometry: 1.0
species: 605346

617605
type: SpeciesReference
stoichiometry: 1.0
species: 608006

617629
type: SpeciesReference
stoichiometry: 1.0
species: 605418

617592
type: SpeciesReference
stoichiometry: 2.0
species: 590126

617641
type: SpeciesReference
stoichiometry: 1.0
species: 605296

617665
type: SpeciesReference
stoichiometry: 3.0
species: 605346

617520
type: SpeciesReference
stoichiometry: 3.0
species: 605296

617496
type: SpeciesReference
stoichiometry: 1.0
species: 605479

617484
type: SpeciesReference
stoichiometry: 1.0
species: 607958

617508
type: SpeciesReference
stoichiometry: 1.0
species: 584822

617617
type: SpeciesReference
stoichiometry: 1.0
species: 590138

012487
type: Reaction
is: ENSECAG00000012172.1
product: 647957
product: 647933
reactant: 647884
is: http://identifiers.org/ec-code/2.7.1.105
is: ENSECAG00000009799.1
product: 647920
is: ENSECAG00000017338.1
reactant: 647908
reactant: 647896
is: http://identifiers.org/ec-code/3.1.3.46
is: ENSECAG00000000039.1
reversible: false
product: 647969
product: 647945
notes: R_FBP26 subsystem: Fructose and Mannose Metabolism R_FBP26 equation: [c] : f26bp + h2o --> f6p + pi R_PFK26 subsystem: Fructose and Mannose Metabolism R_PFK26 equation: [c] : atp + f6p --> adp + f26bp + h
reactant: 647872
fast: false

647957
type: SpeciesReference
stoichiometry: 1.0
species: 596300

647933
type: SpeciesReference
stoichiometry: 1.0
species: 607462

647884
type: SpeciesReference
stoichiometry: 1.0
species: 590727

647920
type: SpeciesReference
stoichiometry: 1.0
species: 596276

647908
type: SpeciesReference
stoichiometry: 1.0
species: 599421

647896
type: SpeciesReference
stoichiometry: 1.0
species: 596300

647969
type: SpeciesReference
stoichiometry: 1.0
species: 599531

647945
type: SpeciesReference
stoichiometry: 1.0
species: 589206

647872
type: SpeciesReference
stoichiometry: 1.0
species: 596276

595558
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584413
name: dUDP_C9H11N2O11P2

612192
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: _27-Hydroxycholesterol_C27H46O2

605876
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: nervonyl coenzyme A_C45H76N7O17P3S

010098
type: Reaction
is: http://identifiers.org/ec-code/3.2.1.22
notes: R_GLAl subsystem: Sphingolipid Metabolism R_GLAl equation: [l] : digalside_hs + h2o --> gal + galside_hs
reactant: 626944
name: galactosidase, alpha
fast: false
product: 626980
reactant: 626956
is: ENSECAG00000018500.1
reversible: false
product: 626968

626944
type: SpeciesReference
stoichiometry: 1.0
species: 599457

626980
type: SpeciesReference
stoichiometry: 1.0
species: 597662

626956
type: SpeciesReference
stoichiometry: 1.0
species: 594770

594770
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Digalactosylceramide_C30H56NO12FULLRCO

626968
type: SpeciesReference
stoichiometry: 1.0
species: 597432

599373
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Hydrogen peroxide_H2O2

586845
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: pentaglutamyl folate (DHF)_C39H43N11O18

587176
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: pentaglutamyl folate (THF)_C39H45N11O18

016927
type: Reaction
reactant: 691122
name: urocanase
is: ENSECAG00000021115.1
notes: R_URCN subsystem: Histidine Metabolism R_URCN equation: [c] : h2o + urcan --> 4izp
product: 691135
is: http://identifiers.org/ec-code/4.2.1.49
fast: false
reactant: 691110
reversible: false

691122
type: SpeciesReference
stoichiometry: 1.0
species: 599421

691135
type: SpeciesReference
stoichiometry: 1.0
species: 586460

586460
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _4-Imidazolone-5-propanoate_C6H7N2O3

691110
type: SpeciesReference
stoichiometry: 1.0
species: 611793

611793
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Urocanate_C6H5N2O2

015619
type: Reaction
product: 678056
is: ENSECAG00000005751.1
reactant: 678008
is: ENSECAG00000014649.1
product: 678068
reversible: false
reactant: 678020
is: http://identifiers.org/ec-code/2.4.1.11
product: 678044
is: ENSECAG00000023192.1
is: ENSECAG00000021428.1
notes: R_GLGNS1 subsystem: Starch and Sucrose Metabolism R_GLGNS1 equation: [c] : ggn + (3) udpg --> glygn1 + (3) h + (3) udp R_GGNG subsystem: Starch and Sucrose Metabolism R_GGNG equation: [c] : Tyr-ggn + (8) udpg --> ggn + (8) h + (8) udp
reactant: 677996
product: 678032
fast: false

678056
type: SpeciesReference
stoichiometry: 11.0
species: 611393

678008
type: SpeciesReference
stoichiometry: 1.0
species: 598061

598061
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: primed glycogenin (glycogenin-8[1,4-Glc])_C48H81O41X

678068
type: SpeciesReference
stoichiometry: 11.0
species: 599531

678020
type: SpeciesReference
stoichiometry: 1.0
species: 588167

588167
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Tyr-194 of apo-glycogenin protein (primer for glycogen synthesis)_XOH

678044
type: SpeciesReference
stoichiometry: 1.0
species: 598061

677996
type: SpeciesReference
stoichiometry: 11.0
species: 611525

678032
type: SpeciesReference
stoichiometry: 1.0
species: 598663

603493
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: alpha-linolenyl carnitine_C25H43NO4

598868
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: GlcNAc-alpha-1,4-Core 1_C22H37N2O15X

014779
type: Reaction
is: ENSECAG00000013175.1
reversible: false
product: 669605
is: ENSECAG00000006376.1
product: 669593
reactant: 669557
reactant: 669581
name: L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)
reactant: 669569
is: http://identifiers.org/ec-code/1.14.16.4
notes: R_TRPHYDRO2 subsystem: Tryptophan metabolism R_TRPHYDRO2 equation: [c] : o2 + thbpt + trp-L --> 5htrp + thbpt4acam
fast: false

669605
type: SpeciesReference
stoichiometry: 1.0
species: 587020

669593
type: SpeciesReference
stoichiometry: 1.0
species: 610487

669557
type: SpeciesReference
stoichiometry: 1.0
species: 610499

669581
type: SpeciesReference
stoichiometry: 1.0
species: 605960

669569
type: SpeciesReference
stoichiometry: 1.0
species: 611090

011667
type: Reaction
product: 640428
product: 640452
is: ENSECAG00000014291.1
fast: false
reactant: 640404
notes: R_PAFH subsystem: Glycerophospholipid Metabolism R_PAFH equation: [c] : h2o + paf_hs --> ac + ak2lgchol_hs + h
reversible: false
is: ENSECAG00000018377.1
reactant: 640416
product: 640440
is: ENSECAG00000010970.1
name: Platelet-activating factor acetylhydrolase
is: http://identifiers.org/ec-code/3.1.1.47
is: ENSECAG00000015859.1

640428
type: SpeciesReference
stoichiometry: 1.0
species: 588264

640452
type: SpeciesReference
stoichiometry: 1.0
species: 599531

640404
type: SpeciesReference
stoichiometry: 1.0
species: 606648

606648
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens)_C11H23O4NPFULLRCO2

640416
type: SpeciesReference
stoichiometry: 1.0
species: 599421

640440
type: SpeciesReference
stoichiometry: 1.0
species: 589652

589652
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: _1-alkyl 2-lysoglycerol 3-phosphocholine_C10H21O5NPFULLR

009770
type: Reaction
name: Leukotriene C4 synthase
fast: false
product: 623335
reversible: false
reactant: 623311
is: ENSECAG00000000509.1
is: ENSECAG00000022320.1
notes: R_LTC4Sr subsystem: Eicosanoid Metabolism R_LTC4Sr equation: [r] : gthrd + leuktrA4 --> leuktrC4
is: ENSECAG00000019195.1
reactant: 623323

623335
type: SpeciesReference
stoichiometry: 1.0
species: 603168

623311
type: SpeciesReference
stoichiometry: 1.0
species: 603096

603096
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Leukotriene A4_C20H29O3

623323
type: SpeciesReference
stoichiometry: 1.0
species: 599228

603890
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: (alpha-D-Mannosyl)5-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1545H2540N20O470P20

584509
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: _10-formyltetrahydrofolate-[Glu](6)_C45H51N12O22

016394
type: Reaction
is: ENSECAG00000012442.1
product: 687198
reversible: false
reactant: 687174
fast: false
product: 687211
name: globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
notes: R_GBGT1 subsystem: Sphingolipid Metabolism R_GBGT1 equation: [g] : gbside_hs + udpacgal --> acgagbside_hs + h + udp
reactant: 687186
product: 687223

687198
type: SpeciesReference
stoichiometry: 1.0
species: 588554

588554
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: alpha GalNAc globoside (homo sapiens)_C52H92N3O27FULLRCO

687174
type: SpeciesReference
stoichiometry: 1.0
species: 597747

687211
type: SpeciesReference
stoichiometry: 1.0
species: 611417

687186
type: SpeciesReference
stoichiometry: 1.0
species: 611489

687223
type: SpeciesReference
stoichiometry: 1.0
species: 599556

017229
type: Reaction
modifier: 693884
notes: R_GCCbim subsystem: Glycine, Serine, and Threonine Metabolism R_GCCbim equation: [m] : alpro + thf --> dhlpro + mlthf + nh4 R_GCCcm subsystem: Glycine, Serine, and Threonine Metabolism R_GCCcm equation: [m] : dhlpro + nad <==> h + lpro + nadh R_GCC2bim subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2bim equation: [m] : alpam + thf --> dhlam + mlthf + nh4 R_GCCam subsystem: Glycine, Serine, and Threonine Metabolism R_GCCam equation: [m] : gly + h + lpro <==> alpro + co2 R_GCC2cm subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2cm equation: [m] : dhlam + nad <==> h + lpam + nadh R_GCC2am subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2am equation: [m] : gly + h + lpam <==> alpam + co2
is: http://identifiers.org/ec-code/2.1.2.10
modifier: 693860
modifier: 693800
reversible: false
is: http://identifiers.org/ec-code/1.4.4.2
modifier: 693824
modifier: 693848
reactant: 693727
is: ENSECAG00000012159.1
product: 693752
modifier: 693896
modifier: 693872
is: http://identifiers.org/ec-code/1.8.1.4
modifier: 693908
modifier: 693836
product: 693788
reactant: 693740
modifier: 693812
reactant: 693715
product: 693776
fast: false
modifier: 693920
is: ENSECAG00000010726.1
product: 693764

693727
type: SpeciesReference
stoichiometry: 1.0
species: 589956

693752
type: SpeciesReference
stoichiometry: 1.0
species: 594672

693788
type: SpeciesReference
stoichiometry: 2.0
species: 604886

693740
type: SpeciesReference
stoichiometry: 2.0
species: 610644

693715
type: SpeciesReference
stoichiometry: 1.0
species: 589944

693776
type: SpeciesReference
stoichiometry: 1.0
species: 594660

693764
type: SpeciesReference
stoichiometry: 2.0
species: 605587

010640
type: Reaction
is: ENSECAG00000020201.1
reactant: 632127
product: 632175
reactant: 632115
reversible: false
product: 632163
notes: R_CORE2GTg subsystem: O-Glycan Biosynthesis R_CORE2GTg equation: [g] : T_antigen + uacgam --> core2 + h + udp R_CORE6GTg subsystem: O-Glycan Biosynthesis R_CORE6GTg equation: [g] : Tn_antigen + uacgam --> core6 + h + udp
product: 632139
fast: false
reactant: 632103
is: http://identifiers.org/ec-code/2.4.1.102
product: 632151

632127
type: SpeciesReference
stoichiometry: 1.0
species: 588142

632175
type: SpeciesReference
stoichiometry: 1.0
species: 592438

632115
type: SpeciesReference
stoichiometry: 1.0
species: 588130

632163
type: SpeciesReference
stoichiometry: 1.0
species: 592474

592474
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: Core 6_C16H27N2O10X

632139
type: SpeciesReference
stoichiometry: 2.0
species: 611417

632103
type: SpeciesReference
stoichiometry: 2.0
species: 611381

632151
type: SpeciesReference
stoichiometry: 2.0
species: 599556

609569
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Sphinganine_C18H40NO2

594940
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: N,N-Dimethylglycine_C4H9NO2

017433
type: Reaction
product: 696673
fast: false
reactant: 696661
is: http://identifiers.org/ec-code/4.3.1.3
name: histidase
reversible: false
product: 696685
notes: R_HISD subsystem: Histidine Metabolism R_HISD equation: [c] : his-L --> nh4 + urcan
is: ENSECAG00000008161.1

696673
type: SpeciesReference
stoichiometry: 1.0
species: 611793

696661
type: SpeciesReference
stoichiometry: 1.0
species: 600025

696685
type: SpeciesReference
stoichiometry: 1.0
species: 605563

595169
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Dolichyl phosphate D-mannose, human liver homolog_C1140H1868O90P10

013574
type: Reaction
product: 659513
product: 659452
product: 659525
is: ENSECAG00000022837.1
reactant: 659428
reactant: 659356
is: http://identifiers.org/ec-code/4.1.1.9
reactant: 659404
reactant: 659368
reactant: 659332
reversible: false
reactant: 659380
is: http://identifiers.org/ec-code/4.1.1.41
reactant: 659416
product: 659500
product: 659488
product: 659464
reactant: 659344
product: 659537
product: 659476
reactant: 659392
product: 659440
notes: R_MMCDm subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMCDm equation: [m] : h + mmcoa-S --> co2 + ppcoa R_MMCDp subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMCDp equation: [x] : h + mmcoa-S --> co2 + ppcoa R_MMCD subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMCD equation: [c] : h + mmcoa-S --> co2 + ppcoa R_MCDp subsystem: Fatty Acid Metabolism R_MCDp equation: [x] : h + malcoa --> accoa + co2 R_MCD subsystem: Fatty Acid Metabolism R_MCD equation: [c] : h + malcoa --> accoa + co2 R_MCDm subsystem: Fatty Acid Metabolism R_MCDm equation: [m] : h + malcoa --> accoa + co2
fast: false

659513
type: SpeciesReference
stoichiometry: 2.0
species: 592269

659452
type: SpeciesReference
stoichiometry: 2.0
species: 592294

659525
type: SpeciesReference
stoichiometry: 1.0
species: 588408

659428
type: SpeciesReference
stoichiometry: 2.0
species: 599581

659356
type: SpeciesReference
stoichiometry: 1.0
species: 604209

659404
type: SpeciesReference
stoichiometry: 1.0
species: 604946

659368
type: SpeciesReference
stoichiometry: 1.0
species: 604221

604221
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584425
name: Malonyl-CoA_C24H33N7O19P3S

659332
type: SpeciesReference
stoichiometry: 1.0
species: 604922

604922
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: (S)-Methylmalonyl-CoA_C25H35N7O19P3S

659380
type: SpeciesReference
stoichiometry: 1.0
species: 604197

659416
type: SpeciesReference
stoichiometry: 2.0
species: 599531

659500
type: SpeciesReference
stoichiometry: 1.0
species: 607691

607691
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: Propanoyl-CoA_C24H36N7O17P3S

659488
type: SpeciesReference
stoichiometry: 1.0
species: 607703

659464
type: SpeciesReference
stoichiometry: 1.0
species: 607715

659344
type: SpeciesReference
stoichiometry: 1.0
species: 604934

604934
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584401
name: (S)-Methylmalonyl-CoA_C25H35N7O19P3S

659537
type: SpeciesReference
stoichiometry: 1.0
species: 588470

659476
type: SpeciesReference
stoichiometry: 1.0
species: 588432

659392
type: SpeciesReference
stoichiometry: 2.0
species: 599617

659440
type: SpeciesReference
stoichiometry: 2.0
species: 592318

593136
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584377
name: chondroitin sulfate D (GlcNAc6S-GlcA2S) precursor 2_C31H46NO34S3X

012173
type: Reaction
fast: false
product: 644327
reactant: 644267
is: ENSECAG00000007467.1
is: http://identifiers.org/ec-code/1.3.99.3
reactant: 644291
product: 644315
notes: R_PPCOAOm subsystem: Propanoate Metabolism R_PPCOAOm equation: [m] : fad + ppcoa --> fadh2 + prpncoa R_ACOAD1fm subsystem: Butanoate Metabolism R_ACOAD1fm equation: [m] : btcoa + fad --> b2coa + fadh2
is: ENSECAG00000010402.1
is: ENSECAG00000013793.1
reactant: 644279
is: ENSECAG00000005530.1
product: 644303
reversible: false
is: http://identifiers.org/ec-code/1.3.99.2

644327
type: SpeciesReference
stoichiometry: 1.0
species: 590799

644267
type: SpeciesReference
stoichiometry: 1.0
species: 591088

644291
type: SpeciesReference
stoichiometry: 2.0
species: 596324

644315
type: SpeciesReference
stoichiometry: 1.0
species: 608367

644279
type: SpeciesReference
stoichiometry: 1.0
species: 607703

644303
type: SpeciesReference
stoichiometry: 2.0
species: 596372

015175
type: Reaction
is: ENSECAG00000009297.1
product: 672991
notes: R_PCLYSOX subsystem: Lysine Metabolism R_PCLYSOX equation: [c] : akg + o2 + pcollglys --> co2 + pcollg5hlys + succ
is: http://identifiers.org/ec-code/1.14.11.4
is: ENSECAG00000021913.1
product: 672979
reactant: 672954
fast: false
reactant: 672930
reversible: false
name: Procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase
reactant: 672942
is: ENSECAG00000022842.1
product: 672967

672991
type: SpeciesReference
stoichiometry: 1.0
species: 592269

672979
type: SpeciesReference
stoichiometry: 1.0
species: 609896

672954
type: SpeciesReference
stoichiometry: 1.0
species: 605960

672930
type: SpeciesReference
stoichiometry: 1.0
species: 607037

672942
type: SpeciesReference
stoichiometry: 1.0
species: 589688

672967
type: SpeciesReference
stoichiometry: 1.0
species: 607025

011968
type: Reaction
product: 642657
reactant: 642597
reactant: 642621
reversible: false
fast: false
notes: R_PIK3 subsystem: Inositol Phosphate Metabolism R_PIK3 equation: [c] : atp + pail_hs --> adp + h + pail3p_hs R_PI5P3K subsystem: Inositol Phosphate Metabolism R_PI5P3K equation: [c] : atp + pail5p_hs --> adp + h + pail35p_hs
product: 642633
product: 642645
is: ENSECAG00000010657.1
product: 642669
reactant: 642609
is: http://identifiers.org/ec-code/2.7.1.137

642657
type: SpeciesReference
stoichiometry: 1.0
species: 606746

642597
type: SpeciesReference
stoichiometry: 1.0
species: 606831

642621
type: SpeciesReference
stoichiometry: 1.0
species: 606855

642633
type: SpeciesReference
stoichiometry: 1.0
species: 606722

642645
type: SpeciesReference
stoichiometry: 2.0
species: 589206

642669
type: SpeciesReference
stoichiometry: 2.0
species: 599531

642609
type: SpeciesReference
stoichiometry: 2.0
species: 590727

018058
type: Reaction
product: 701990
fast: false
reversible: false
reactant: 701978
is: ENSECAG00000017797.1
is: http://identifiers.org/ec-code/4.1.1.45
reactant: 701966
notes: R_PCLAD subsystem: Tryptophan metabolism R_PCLAD equation: [c] : cmusa + h --> am6sa + co2
name: picolinic acid decarboxylase
product: 702002

701990
type: SpeciesReference
stoichiometry: 1.0
species: 592269

701978
type: SpeciesReference
stoichiometry: 1.0
species: 599531

701966
type: SpeciesReference
stoichiometry: 1.0
species: 592257

702002
type: SpeciesReference
stoichiometry: 1.0
species: 589968

010338
type: Reaction
reactant: 629135
reactant: 629026
notes: R_DALAt2r subsystem: Transport, Extracellular R_DALAt2r equation: ala-D[e] + h[e] <==> ala-D[c] + h[c] R_ALAt2rL subsystem: Transport, Lysosomal R_ALAt2rL equation: ala-L[l] + h[l] <==> ala-L[c] + h[c] R_DALAt2rL subsystem: Transport, Lysosomal R_DALAt2rL equation: ala-D[l] + h[l] <==> ala-D[c] + h[c] R_ABUTt2r subsystem: Transport, Extracellular R_ABUTt2r equation: _4abut[e] + h[e] <==> 4abut[c] + h[c] R_PROt2r subsystem: Transport, Extracellular R_PROt2r equation: h[e] + pro-L[e] <==> h[c] + pro-L[c] R_ALAt2r subsystem: Transport, Extracellular R_ALAt2r equation: ala-L[e] + h[e] <==> ala-L[c] + h[c] R_GLYt2r subsystem: Transport, Extracellular R_GLYt2r equation: gly[e] + h[e] <==> gly[c] + h[c] R_PRODt2rL subsystem: Transport, Lysosomal R_PRODt2rL equation: h[l] + pro-D[l] <==> h[c] + pro-D[c] R_PROt2rL subsystem: Transport, Lysosomal R_PROt2rL equation: h[l] + pro-L[l] <==> h[c] + pro-L[c] R_PRODt2r subsystem: Transport, Extracellular R_PRODt2r equation: h[e] + pro-D[e] <==> h[c] + pro-D[c] R_ABUTt2rL subsystem: Transport, Lysosomal R_ABUTt2rL equation: _4abut[l] + h[l] <==> 4abut[c] + h[c] R_GLYt2rL subsystem: Transport, Lysosomal R_GLYt2rL equation: gly[l] + h[l] <==> gly[c] + h[c]
product: 629159
product: 629219
product: 629207
reactant: 629111
reactant: 629099
product: 629171
reactant: 629087
is: ENSECAG00000025152.1
reactant: 629001
reactant: 629050
reactant: 628988
fast: false
reactant: 628975
reactant: 629038
reactant: 629014
reactant: 629123
product: 629183
product: 629195
reactant: 629075
product: 629147
reactant: 629062
reversible: true

629135
type: SpeciesReference
stoichiometry: 1.0
species: 608114

608114
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: D-Proline_C5H9NO2

629026
type: SpeciesReference
stoichiometry: 1.0
species: 589847

629159
type: SpeciesReference
stoichiometry: 2.0
species: 598446

629219
type: SpeciesReference
stoichiometry: 12.0
species: 599531

629207
type: SpeciesReference
stoichiometry: 2.0
species: 589785

629111
type: SpeciesReference
stoichiometry: 1.0
species: 589809

629099
type: SpeciesReference
stoichiometry: 1.0
species: 586278

586278
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: _4-Aminobutanoate_C4H9NO2

629171
type: SpeciesReference
stoichiometry: 2.0
species: 608090

608090
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584341
name: D-Proline_C5H9NO2

629087
type: SpeciesReference
stoichiometry: 1.0
species: 586291

586291
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: _4-Aminobutanoate_C4H9NO2

629001
type: SpeciesReference
stoichiometry: 6.0
species: 599544

629050
type: SpeciesReference
stoichiometry: 1.0
species: 608150

628988
type: SpeciesReference
stoichiometry: 1.0
species: 589797

628975
type: SpeciesReference
stoichiometry: 1.0
species: 608102

608102
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: D-Proline_C5H9NO2

629038
type: SpeciesReference
stoichiometry: 6.0
species: 599568

629014
type: SpeciesReference
stoichiometry: 1.0
species: 589859

589859
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: L-Alanine_C3H7NO2

629123
type: SpeciesReference
stoichiometry: 1.0
species: 598470

598470
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: Glycine_C2H5NO2

629183
type: SpeciesReference
stoichiometry: 2.0
species: 589834

629195
type: SpeciesReference
stoichiometry: 2.0
species: 608138

629075
type: SpeciesReference
stoichiometry: 1.0
species: 598458

629147
type: SpeciesReference
stoichiometry: 2.0
species: 586265

629062
type: SpeciesReference
stoichiometry: 1.0
species: 608162

608162
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584389
name: L-Proline_C5H9NO2

011981
type: Reaction
product: 642838
reactant: 642681
reversible: false
reactant: 642705
is: ENSECAG00000024054.1
fast: false
product: 642766
notes: R_ADRNLPVESSEC subsystem: Transport, Extracellular R_ADRNLPVESSEC equation: (3) adrnl[c] + (2) atp[c] + (2) h2o[c] --> (2) adp[c] + (3) adrnl[e] + (2) h[c] + (2) pi[c] R_5HTRPVESSEC subsystem: Transport, Extracellular R_5HTRPVESSEC equation: (3) 5htrp[c] + (2) atp[c] + (2) h2o[c] --> (3) 5htrp[e] + (2) adp[c] + (2) h[c] + (2) pi[c] R_NRPPHRVESSEC subsystem: Transport, Extracellular R_NRPPHRVESSEC equation: (2) atp[c] + (2) h2o[c] + (3) nrpphr[c] --> (2) adp[c] + (2) h[c] + (3) nrpphr[e] + (2) pi[c] R_HISTAVESSEC subsystem: Transport, Extracellular R_HISTAVESSEC equation: (2) atp[c] + (2) h2o[c] + (3) hista[c] --> (2) adp[c] + (2) h[c] + (3) hista[e] + (2) pi[c] R_DOPAVESSEC subsystem: Transport, Extracellular R_DOPAVESSEC equation: (2) atp[c] + (3) dopa[c] + (2) h2o[c] --> (2) adp[c] + (3) dopa[e] + (2) h[c] + (2) pi[c]
reactant: 642742
product: 642790
product: 642778
product: 642850
reactant: 642693
reactant: 642717
product: 642802
is: ENSECAG00000013343.1
product: 642814
reactant: 642729
reactant: 642754
product: 642826

642838
type: SpeciesReference
stoichiometry: 3.0
species: 587032

587032
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: _5-Hydroxy-L-tryptophan_C11H12N2O3

642681
type: SpeciesReference
stoichiometry: 3.0
species: 605816

642705
type: SpeciesReference
stoichiometry: 10.0
species: 590727

642766
type: SpeciesReference
stoichiometry: 10.0
species: 607462

642742
type: SpeciesReference
stoichiometry: 3.0
species: 595266

642790
type: SpeciesReference
stoichiometry: 3.0
species: 595279

642778
type: SpeciesReference
stoichiometry: 3.0
species: 589459

642850
type: SpeciesReference
stoichiometry: 10.0
species: 599531

642693
type: SpeciesReference
stoichiometry: 3.0
species: 589446

642717
type: SpeciesReference
stoichiometry: 3.0
species: 600049

642802
type: SpeciesReference
stoichiometry: 3.0
species: 600061

600061
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584365
name: Histamine_C5H10N3

642814
type: SpeciesReference
stoichiometry: 10.0
species: 589206

642729
type: SpeciesReference
stoichiometry: 3.0
species: 587020

642754
type: SpeciesReference
stoichiometry: 10.0
species: 599421

642826
type: SpeciesReference
stoichiometry: 3.0
species: 605828

018851
type: Reaction
reversible: false
notes: R_SGPL12r subsystem: Sphingolipid Metabolism R_SGPL12r equation: [r] : h2o + sphs1p --> ethamp + h + hdca R_SGPL11r subsystem: Sphingolipid Metabolism R_SGPL11r equation: [r] : sph1p --> ethamp + hxdcal
reactant: 710947
is: ENSECAG00000016826.1
product: 710959
product: 710971
fast: false
product: 710995
product: 710983
is: http://identifiers.org/ec-code/4.1.2.27
reactant: 710935
reactant: 710923

710947
type: SpeciesReference
stoichiometry: 1.0
species: 599493

710959
type: SpeciesReference
stoichiometry: 1.0
species: 599773

710971
type: SpeciesReference
stoichiometry: 2.0
species: 596213

710995
type: SpeciesReference
stoichiometry: 1.0
species: 599605

710983
type: SpeciesReference
stoichiometry: 1.0
species: 600840

600840
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 584353
name: Hexadecanal_C16H32O