MODEL1008120004
type: SBMLModel
species: 467510
reaction: 995136
species: 457997
species: 451756
reaction: 988778
species: 448934
species: 451876
reaction: 995496
species: 452009
reaction: 993277
species: 465355
species: 471685
species: 450299
species: 463611
species: 463951
species: 454098
species: 469178
species: 462174
species: 460825
reaction: 988790
species: 454547
species: 444901
species: 470701
species: 461823
species: 450671
species: 449344
reaction: 996554
species: 463624
species: 451434
species: 453928
species: 447749
reaction: 995208
species: 466226
species: 457840
species: 464494
species: 469564
species: 470023
species: 461225
species: 444587
reaction: 988298
species: 466543
species: 454727
reaction: 991488
species: 471649
species: 452190
species: 463915
species: 457816
species: 466748
species: 447822
reaction: 991572
species: 468899
species: 459565
reaction: 987937
species: 453674
reaction: 988406
species: 459685
species: 468358
reaction: 991464
species: 445926
species: 466070
reaction: 992209
species: 451084
species: 460546
reaction: 996943
species: 468443
species: 465949
species: 445613
reaction: 987877
species: 447129
species: 469939
species: 445095
species: 458239
species: 469721
species: 460971
reaction: 991873
species: 455751
species: 451606
species: 457211
species: 449681

467510
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Prostaglandin D2_C20H31O5

443622
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

995136
type: Reaction
reversible: false
product: 546797
product: 546785
fast: false
is: ENSBTAG00000007001.2
notes: R_OXAHCOtex subsystem: Transport, Extracellular R_OXAHCOtex equation: (2) hco3[c] + oxa[e] --> (2) hco3[e] + oxa[c] R_SO4HCOtex subsystem: Transport, Extracellular R_SO4HCOtex equation: (2) hco3[c] + so4[e] --> (2) hco3[e] + so4[c]
reactant: 546773
reactant: 546749
reactant: 546761
product: 546809

546797
type: SpeciesReference
stoichiometry: 1.0
species: 468743

468743
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Sulfate_O4S

443610
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

546785
type: SpeciesReference
stoichiometry: 1.0
species: 465804

465804
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Oxalate_C2O4

546773
type: SpeciesReference
stoichiometry: 1.0
species: 468755

468755
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Sulfate_O4S

443634
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

546749
type: SpeciesReference
stoichiometry: 4.0
species: 458952

458952
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Bicarbonate_CHO3

546761
type: SpeciesReference
stoichiometry: 1.0
species: 465816

465816
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Oxalate_C2O4

546809
type: SpeciesReference
stoichiometry: 4.0
species: 458964

458964
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Bicarbonate_CHO3

457997
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: ganglioside GM1 (homo sapiens)_C55H95N3O30FULLRCO

443646
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

451756
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Cortisone_C21H28O5

988778
type: Reaction
reactant: 486163
name: galactosidase, alpha
notes: R_GLAl subsystem: Sphingolipid Metabolism R_GLAl equation: [l] : digalside_hs + h2o --> gal + galside_hs
product: 486187
product: 486175
reactant: 486151
is: ENSBTAG00000019256.4
fast: false
is: http://identifiers.org/ec-code/3.2.1.22
reversible: false

486163
type: SpeciesReference
stoichiometry: 1.0
species: 454026

454026
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Digalactosylceramide_C30H56NO12FULLRCO

443658
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

486187
type: SpeciesReference
stoichiometry: 1.0
species: 456921

456921
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: galactocerebroside (homo sapiens)_C24H46NO7FULLRCO

486175
type: SpeciesReference
stoichiometry: 1.0
species: 456689

456689
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: D-Galactose_C6H12O6

486151
type: SpeciesReference
stoichiometry: 1.0
species: 458721

458721
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: H2O_H2O

448934
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: _1-alkyldihydroxyacetone phosphate_C3H4O6PFULLRC2H4

443695
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

451876
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Ceramide 1-phosphate_C18H35NO5PFULLRCO

995496
type: Reaction
reactant: 549559
reactant: 549571
reversible: false
reactant: 549535
product: 549595
is: http://identifiers.org/ec-code/2.1.2.5
is: http://identifiers.org/ec-code/4.3.1.4
product: 549583
notes: R_GluForTx subsystem: Histidine Metabolism R_GluForTx equation: [c] : forglu + h + thf --> 5forthf + glu-L R_FTCD subsystem: Folate Metabolism R_FTCD equation: [c] : 5forthf + (2) h --> methf + nh4
reactant: 549547
product: 549619
product: 549607
is: ENSBTAG00000020404.4
fast: false

549559
type: SpeciesReference
stoichiometry: 1.0
species: 446154

446154
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-Formiminotetrahydrofolate_C20H22N8O6

549571
type: SpeciesReference
stoichiometry: 3.0
species: 458794

458794
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: H+_H

549535
type: SpeciesReference
stoichiometry: 1.0
species: 469878

469878
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5,6,7,8-Tetrahydrofolate_C19H21N7O6

549595
type: SpeciesReference
stoichiometry: 1.0
species: 463855

463855
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5,10-Methenyltetrahydrofolate_C20H20N7O6

549583
type: SpeciesReference
stoichiometry: 1.0
species: 464834

464834
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Ammonium_H4N

549547
type: SpeciesReference
stoichiometry: 1.0
species: 455920

455920
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Formimidoyl-L-glutamate_C6H8N2O4

549619
type: SpeciesReference
stoichiometry: 1.0
species: 446154

549607
type: SpeciesReference
stoichiometry: 1.0
species: 457525

457525
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Glutamate_C5H8NO4

452009
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate/heparan sulfate linkage region (GlcA-(Gal)2-Xyl-L-Ser (protein))_C23H36O20X

993277
type: Reaction
reactant: 527059
is: ENSBTAG00000015511.4
reactant: 527071
reactant: 527047
reversible: false
notes: R_DESAT20_1 subsystem: Fatty acid elongation R_DESAT20_1 equation: [c] : dlnlcgcoa + h + nadh + o2 --> arachdcoa + (2) h2o + nad R_DESAT20_2 subsystem: Fatty acid elongation R_DESAT20_2 equation: [c] : eicostetcoa + h + nadh + o2 --> (2) h2o + nad + tmndnccoa
is: ENSBTAG00000030920.2
is: ENSBTAG00000022294.3
reactant: 527035
reactant: 527083
product: 527120
product: 527107
product: 527095
product: 527132
is: http://identifiers.org/ec-code/1.14.19.1
fast: false
is: ENSBTAG00000031017.2

527059
type: SpeciesReference
stoichiometry: 2.0
species: 465234

465234
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: O2_O2

527071
type: SpeciesReference
stoichiometry: 2.0
species: 458794

527047
type: SpeciesReference
stoichiometry: 1.0
species: 455064

455064
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: eicosatetranoyl coenzyme A_C41H62N7O17P3S

527035
type: SpeciesReference
stoichiometry: 1.0
species: 454123

454123
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dihomo-gamma-linolenyl coenzyme A_C41H64N7O17P3S

527083
type: SpeciesReference
stoichiometry: 2.0
species: 464590

464590
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

527120
type: SpeciesReference
stoichiometry: 1.0
species: 470180

470180
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: timnodonyl coenzyme A_C41H60N7O17P3S

527107
type: SpeciesReference
stoichiometry: 2.0
species: 464518

464518
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

527095
type: SpeciesReference
stoichiometry: 1.0
species: 449729

449729
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: C20:4-CoA_C41H62N7O17P3S

527132
type: SpeciesReference
stoichiometry: 4.0
species: 458685

458685
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: H2O_H2O

465355
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Superoxide anion_O2

471685
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _7-alpha,25-Dihydroxycholesterol_C27H46O3

450299
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Biocytin_C16H28N4O4S

443670
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

463611
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: D-Mannose_C6H12O6

463951
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1D-myo-Inositol 1,3,4,5-tetrakisphosphate_C6H8O18P4

454098
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: dITP_C10H11N4O13P3

443682
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

469178
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Succinate_C4H4O4

462174
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Lactate_C3H5O3

460825
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 22_C132H214N9O111S5

988790
type: Reaction
is: ENSBTAG00000020774.3
notes: R_ADK3m subsystem: Nucleotides R_ADK3m equation: [m] : amp + gtp <==> adp + gdp
is: ENSBTAG00000030674.2
reactant: 486199
is: ENSBTAG00000017147.3
product: 486237
reversible: true
fast: false
product: 486224
reactant: 486212
name: adentylate kinase (GTP)

486199
type: SpeciesReference
stoichiometry: 1.0
species: 458528

458528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: GTP_C10H12N5O14P3

486237
type: SpeciesReference
stoichiometry: 1.0
species: 457235

457235
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: GDP_C10H12N5O11P2

486224
type: SpeciesReference
stoichiometry: 1.0
species: 448486

448486
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: ADP_C10H12N5O10P2

486212
type: SpeciesReference
stoichiometry: 1.0
species: 449344

449344
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: AMP_C10H12N5O7P

454547
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Dopaquinone_C9H9NO4

444901
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695

470701
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: UDP_C9H11N2O12P2

461823
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 4_C53H86N4O38X

450671
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Cob(II)alamin_C62H92CoN13O14P

996554
type: Reaction
reactant: 559579
is: http://identifiers.org/ec-code/4.2.1.46
fast: false
product: 559591
product: 559603
notes: R_TDPGDH subsystem: Nucleotide Sugar Metabolism R_TDPGDH equation: [c] : dtdpglu --> dtdp4d6dg + h2o
is: ENSBTAG00000005309.4
name: dTDPglucose 4,6-dehydratase
reversible: false

559579
type: SpeciesReference
stoichiometry: 1.0
species: 454679

454679
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dTDPglucose_C16H24N2O16P2

559591
type: SpeciesReference
stoichiometry: 1.0
species: 454631

454631
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610

559603
type: SpeciesReference
stoichiometry: 1.0
species: 458685

463624
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: D-Mannose_C6H12O6

451434
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: CMP_C9H12N3O8P

453928
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Dihydrolipolprotein_H2S2X

447749
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Acetone_C3H6O

995208
type: Reaction
reactant: 547243
product: 547267
reactant: 547231
product: 547279
is: http://identifiers.org/ec-code/2.4.1.22
name: UDPgalactose:D-glucose 4-beta-D-galactosyltransferase, Golgi apparatus
product: 547255
reversible: false
is: ENSBTAG00000005859.1
fast: false
notes: R_UGALGTg subsystem: Galactose metabolism R_UGALGTg equation: [g] : glc-D + udpgal --> h + lcts + udp

547243
type: SpeciesReference
stoichiometry: 1.0
species: 470848

470848
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: UDPgalactose_C15H22N2O17P2

547267
type: SpeciesReference
stoichiometry: 1.0
species: 470688

470688
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: UDP_C9H11N2O12P2

547231
type: SpeciesReference
stoichiometry: 1.0
species: 457380

457380
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: D-Glucose_C6H12O6

547279
type: SpeciesReference
stoichiometry: 1.0
species: 458819

458819
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: H+_H

547255
type: SpeciesReference
stoichiometry: 1.0
species: 462294

462294
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Lactose_C12H22O11

466226
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: _3'-Phosphoadenylyl sulfate_C10H11N5O13P2S

457840
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: (S)-Glycerate_C3H5O4

464494
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Sodium_Na

469564
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: tetracosapentaenoyl coenzyme A, n-3_C45H68N7O17P3S

470023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Threonine_C4H9NO3

461225
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 12_C135H218N9O106S3X

444587
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _2-Oxoadipate_C6H6O5

988298
type: Reaction
notes: R_S26Tg subsystem: N-Glycan Biosynthesis R_S26Tg equation: [g] : (2) cmpacna + l2fn2m2masn --> (2) cmp + (2) h + s2l2fn2m2masn
is: http://identifiers.org/ec-code/2.4.99.1
product: 481233
product: 481221
reversible: false
name: beta-galactoside alpha-2,6-sialyltransferase
fast: false
product: 481209
reactant: 481185
reactant: 481197
is: ENSBTAG00000010357.4

481233
type: SpeciesReference
stoichiometry: 1.0
species: 468261

468261
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: PA6_C90H145N6O65X

481221
type: SpeciesReference
stoichiometry: 2.0
species: 451422

451422
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: CMP_C9H12N3O8P

481209
type: SpeciesReference
stoichiometry: 2.0
species: 458819

481185
type: SpeciesReference
stoichiometry: 2.0
species: 451471

451471
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: CMP-N-acetylneuraminate_C20H29N4O16P

481197
type: SpeciesReference
stoichiometry: 1.0
species: 462090

462090
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646

466543
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: phosphatidylglycerol (homo sapiens)_C6H12O6PFULLRCO2FULLR2CO2

454727
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Oxidized dithiothreitol_C4H8O2S2

991488
type: Reaction
name: Hydroxymethylglutaryl CoA synthase (ir)
reactant: 510031
product: 510044
reactant: 510019
notes: R_HMGCOASim subsystem: Cholesterol Metabolism R_HMGCOASim equation: [m] : aacoa + accoa + h2o --> coa + h + hmgcoa
is: http://identifiers.org/ec-code/4.1.3.5
reactant: 510006
product: 510068
reversible: false
is: ENSBTAG00000003898.4
fast: false
product: 510056

510031
type: SpeciesReference
stoichiometry: 1.0
species: 447689

447689
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Acetyl-CoA_C23H34N7O17P3S

510044
type: SpeciesReference
stoichiometry: 1.0
species: 451632

451632
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Coenzyme A_C21H32N7O16P3S

510019
type: SpeciesReference
stoichiometry: 1.0
species: 447461

447461
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Acetoacetyl-CoA_C25H36N7O18P3S

510006
type: SpeciesReference
stoichiometry: 1.0
species: 458733

458733
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: H2O_H2O

510068
type: SpeciesReference
stoichiometry: 1.0
species: 458843

458843
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: H+_H

510056
type: SpeciesReference
stoichiometry: 1.0
species: 459361

459361
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670

471649
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: cholesterol ester_C27H45XCO2

452190
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate B (IdoA2S-GalNAc4s), precursor 5_C45H66N2O45S3X

463915
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Methylhistamine_C6H12N3

457816
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Glycerol 3-phosphate_C3H7O6P

466748
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Phosphate_HO4P

447822
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: alpha GalNAc globoside (homo sapiens)_C52H92N3O27FULLRCO

991572
type: Reaction
reactant: 510636
is: ENSBTAG00000035770.1
reversible: false
reactant: 510722
reactant: 510612
notes: R_MM5bg subsystem: N-Glycan Biosynthesis R_MM5bg equation: [g] : h2o + m5masnB1 --> m4masn + man R_MM7Cbg subsystem: N-Glycan Biosynthesis R_MM7Cbg equation: [g] : h2o + m7masnC --> m6masnC + man R_MM6B2g subsystem: N-Glycan Biosynthesis R_MM6B2g equation: [g] : h2o + m6masnB2 --> m5masnB2 + man R_MM6bg subsystem: N-Glycan Biosynthesis R_MM6bg equation: [g] : h2o + m6masnC --> m5masnC + man R_MM8Ag subsystem: N-Glycan Biosynthesis R_MM8Ag equation: [g] : h2o + m8masn --> m7masnA + man R_MM6ag subsystem: N-Glycan Biosynthesis R_MM6ag equation: [g] : h2o + m6masnA --> m5masnC + man R_MM8Cg subsystem: N-Glycan Biosynthesis R_MM8Cg equation: [g] : h2o + m8masn --> m7masnC + man R_MM7Cag subsystem: N-Glycan Biosynthesis R_MM7Cag equation: [g] : h2o + m7masnA --> m6masnC + man R_MM6B1ag subsystem: N-Glycan Biosynthesis R_MM6B1ag equation: [g] : h2o + m6masnB1 --> m5masnB1 + man R_MM7Ag subsystem: N-Glycan Biosynthesis R_MM7Ag equation: [g] : h2o + m7masnA --> m6masnA + man R_MM7B2g subsystem: N-Glycan Biosynthesis R_MM7B2g equation: [g] : h2o + m7masnB --> m6masnB2 + man R_MM6B1bg subsystem: N-Glycan Biosynthesis R_MM6B1bg equation: [g] : h2o + m6masnB2 --> m5masnB1 + man R_MM5ag subsystem: N-Glycan Biosynthesis R_MM5ag equation: [g] : h2o + m5masnC --> m4masn + man R_MM5cg subsystem: N-Glycan Biosynthesis R_MM5cg equation: [g] : h2o + m5masnB2 --> m4masn + man R_MM7B1g subsystem: N-Glycan Biosynthesis R_MM7B1g equation: [g] : h2o + m7masnB --> m6masnB1 + man
fast: false
reactant: 510674
product: 510855
product: 510794
product: 510782
product: 510758
product: 510746
reactant: 510624
reactant: 510649
reactant: 510710
reactant: 510600
product: 510734
reactant: 510661
is: http://identifiers.org/ec-code/3.2.1.113
product: 510843
reactant: 510698
reactant: 510686
product: 510770
product: 510831
product: 510818
reactant: 510588
is: ENSBTAG00000003069.4
product: 510806

510636
type: SpeciesReference
stoichiometry: 15.0
species: 458709

458709
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: H2O_H2O

510722
type: SpeciesReference
stoichiometry: 1.0
species: 463177

463177
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X

510612
type: SpeciesReference
stoichiometry: 1.0
species: 463141

463141
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (alpha-D-mannosyl)5-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C52H87N2O40X

510674
type: SpeciesReference
stoichiometry: 2.0
species: 463249

463249
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform A (protein)_C64H107N2O50X

510855
type: SpeciesReference
stoichiometry: 1.0
species: 463177

510794
type: SpeciesReference
stoichiometry: 2.0
species: 463213

463213
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X

510782
type: SpeciesReference
stoichiometry: 1.0
species: 463189

463189
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X

510758
type: SpeciesReference
stoichiometry: 2.0
species: 463141

510746
type: SpeciesReference
stoichiometry: 1.0
species: 463129

463129
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (alpha-D-mannosyl)5-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C52H87N2O40X

510624
type: SpeciesReference
stoichiometry: 1.0
species: 463286

463286
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform C (protein)_C64H107N2O50X

510649
type: SpeciesReference
stoichiometry: 1.0
species: 463189

510710
type: SpeciesReference
stoichiometry: 1.0
species: 463117

463117
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (alpha-D-mannosyl)5-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C52H87N2O40X

510600
type: SpeciesReference
stoichiometry: 1.0
species: 463129

510734
type: SpeciesReference
stoichiometry: 3.0
species: 463081

463081
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C46H77N2O35X

510661
type: SpeciesReference
stoichiometry: 1.0
species: 463213

510843
type: SpeciesReference
stoichiometry: 2.0
species: 463117

510698
type: SpeciesReference
stoichiometry: 2.0
species: 463322

463322
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C70H117N2O55X

510686
type: SpeciesReference
stoichiometry: 2.0
species: 463201

463201
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X

510770
type: SpeciesReference
stoichiometry: 1.0
species: 463286

510831
type: SpeciesReference
stoichiometry: 15.0
species: 463624

510818
type: SpeciesReference
stoichiometry: 1.0
species: 463201

510588
type: SpeciesReference
stoichiometry: 2.0
species: 463261

463261
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein)_C64H107N2O50X

510806
type: SpeciesReference
stoichiometry: 1.0
species: 463249

468899
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO

459565
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: heparan sulfate, degradation product 13_C55H83N3O61S5

987937
type: Reaction
fast: false
notes: R_METAT subsystem: Methionine Metabolism R_METAT equation: [c] : atp + h2o + met-L --> amet + pi + ppi R_SELMETAT subsystem: Selenoamino acid metabolism R_SELMETAT equation: [c] : atp + h2o + selmeth --> pi + ppi + seasmet
is: ENSBTAG00000005963.3
product: 478029
reversible: false
reactant: 478016
reactant: 477992
is: ENSBTAG00000012350.3
is: http://identifiers.org/ec-code/2.5.1.6
product: 478067
reactant: 478004
product: 478055
product: 478042
reactant: 477980
is: ENSBTAG00000020873.4

478029
type: SpeciesReference
stoichiometry: 2.0
species: 466736

466736
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Phosphate_HO4P

478016
type: SpeciesReference
stoichiometry: 1.0
species: 468563

468563
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Selenomethionine_C5H11NO2Se

477992
type: SpeciesReference
stoichiometry: 2.0
species: 458685

478067
type: SpeciesReference
stoichiometry: 2.0
species: 467000

467000
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Diphosphate_HO7P2

478004
type: SpeciesReference
stoichiometry: 2.0
species: 449983

449983
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: ATP_C10H12N5O13P3

478055
type: SpeciesReference
stoichiometry: 1.0
species: 449236

449236
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: S-Adenosyl-L-methionine_C15H23N6O5S

478042
type: SpeciesReference
stoichiometry: 1.0
species: 468479

468479
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Se-Adenosylselenomethionine_C15H23N6O5Se

477980
type: SpeciesReference
stoichiometry: 1.0
species: 463830

463830
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Methionine_C5H11NO2S

453674
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _6,7-Dihydrobiopterin_C9H13N5O3

988406
type: Reaction
is: ENSBTAG00000032281.1
reversible: false
fast: false
is: ENSBTAG00000017924.3
product: 481957
notes: R_ORNDC subsystem: Urea cycle/amino group metabolism R_ORNDC equation: [c] : h + orn --> co2 + ptrc
is: ENSBTAG00000004256.3
is: ENSBTAG00000034926.2
reactant: 481933
name: Ornithine Decarboxylase
product: 481969
reactant: 481945
is: ENSBTAG00000039994.1
is: http://identifiers.org/ec-code/4.1.1.17

481957
type: SpeciesReference
stoichiometry: 1.0
species: 451519

451519
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: CO2_CO2

481933
type: SpeciesReference
stoichiometry: 1.0
species: 465743

465743
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Ornithine_C5H13N2O2

481969
type: SpeciesReference
stoichiometry: 1.0
species: 467789

467789
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Putrescine_C4H14N2

481945
type: SpeciesReference
stoichiometry: 1.0
species: 458794

459685
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: heparan sulfate, degradation product 22_C37H56NO35S

468358
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Sedoheptulose 7-phosphate_C7H13O10P

991464
type: Reaction
product: 509921
reactant: 509885
reactant: 509897
product: 509909
fast: false
reversible: true
is: http://identifiers.org/ec-code/5.4.2.8
notes: R_PMANM subsystem: Fructose and Mannose Metabolism R_PMANM equation: [c] : man1p <==> man6p R_PGMT subsystem: Glycolysis/Gluconeogenesis R_PGMT equation: [c] : g1p <==> g6p
is: ENSBTAG00000005773.4
is: http://identifiers.org/ec-code/5.4.2.2

509921
type: SpeciesReference
stoichiometry: 1.0
species: 463587

463587
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Mannose 6-phosphate_C6H11O9P

509885
type: SpeciesReference
stoichiometry: 1.0
species: 456451

456451
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Glucose 1-phosphate_C6H11O9P

509897
type: SpeciesReference
stoichiometry: 1.0
species: 463575

463575
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Mannose 1-phosphate_C6H11O9P

509909
type: SpeciesReference
stoichiometry: 1.0
species: 456566

456566
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Glucose 6-phosphate_C6H11O9P

445926
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5,6-Dihydroxyindole-2-carboxylate_C9H6NO4

466070
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

992209
type: Reaction
reactant: 518144
notes: R_AKGMALtm subsystem: Transport, Mitochondrial R_AKGMALtm equation: akg[m] + mal-L[c] <==> akg[c] + mal-L[m]
product: 518168
reversible: true
fast: false
reactant: 518132
name: alpha-ketoglutarate/malate transporter
is: ENSBTAG00000004910.4
product: 518156

518144
type: SpeciesReference
stoichiometry: 1.0
species: 448970

448970
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _2-Oxoglutarate_C5H4O5

518168
type: SpeciesReference
stoichiometry: 1.0
species: 463455

463455
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Malate_C4H4O5

518132
type: SpeciesReference
stoichiometry: 1.0
species: 463443

463443
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Malate_C4H4O5

518156
type: SpeciesReference
stoichiometry: 1.0
species: 448946

448946
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _2-Oxoglutarate_C5H4O5

451084
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Choline phosphate_C5H13NO4P

460546
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Itaconate_C5H4O4

996943
type: Reaction
is: ENSBTAG00000016122.4
notes: R_M4BTAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4BTAer equation: [r] : mem2emgacpail_hs + pre_prot --> gpi_sig + mem2emgacpail_prot_hs R_H8TAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8TAer equation: [r] : gpi_hs + pre_prot --> gpi_prot_hs + gpi_sig R_H7_APOS_TAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7_APOS_TAer equation: [r] : em2emgacpail_hs + pre_prot --> em2emgacpail_prot_hs + gpi_sig
product: 562736
reactant: 562688
product: 562712
reversible: false
reactant: 562651
reactant: 562676
product: 562724
product: 562700
reactant: 562663
fast: false

562736
type: SpeciesReference
stoichiometry: 1.0
species: 463697

463697
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: ({[(mannosyl),(phosphoethanolaminyl)]-dimannosyl},{phosphoethanolaminyl})-mannosyl-glucosaminyl-acylphosphatidylinositol-Protein (M4B)_C59H110N3O40P3FULLRCO2FULLR2CO2X

562688
type: SpeciesReference
stoichiometry: 1.0
species: 463685

463685
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: ({[(mannosyl),(phosphoethanolaminyl)]-dimannosyl},{phosphoethanolaminyl})-mannosyl-glucosaminyl-acylphosphatidylinositol (M4B)_C59H110N3O40P3FULLRCO2FULLR2CO2

562712
type: SpeciesReference
stoichiometry: 1.0
species: 458203

458203
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: glycophosphatidylinositol (GPI)-anchored protein_C55H106N4O38P4FULLRCO2FULLR2CO2X

562651
type: SpeciesReference
stoichiometry: 1.0
species: 455148

455148
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: (phosphoethanolaminyl-dimannosyl),(phosphoethanolaminyl)-mannosyl-glucosaminyl-acylphosphatidylinositol (H7)_C53H100N3O35P3FULLRCO2FULLR2CO2

562676
type: SpeciesReference
stoichiometry: 1.0
species: 458191

458191
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: glycophosphatidylinositol (GPI) anchor precursor (3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol) (H8)_C55H106N4O38P4FULLRCO2FULLR2CO2

562724
type: SpeciesReference
stoichiometry: 1.0
species: 455160

455160
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622

562700
type: SpeciesReference
stoichiometry: 3.0
species: 458215

458215
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: glycophosphatidylinositol (GPI) signal sequence (C-terminal peptide)_Y

562663
type: SpeciesReference
stoichiometry: 3.0
species: 467195

467195
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: glycophosphatidylinositol (GPI)-anchored protein precursor_XY

468443
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Sorbitol_C6H14O6

465949
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)_C9H13O18P4FULLRCO2FULLR2CO2

445613
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-Hydroxy-2-oxoglutarate_C5H4O6

987877
type: Reaction
name: alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
product: 477495
reversible: false
is: ENSBTAG00000038477.1
product: 477483
product: 477507
fast: false
is: http://identifiers.org/ec-code/2.4.1.143
notes: R_M16NTg subsystem: N-Glycan Biosynthesis R_M16NTg equation: [g] : nm2masn + uacgam --> h + n2m2masn + udp
reactant: 477471
reactant: 477459

477495
type: SpeciesReference
stoichiometry: 1.0
species: 470688

477483
type: SpeciesReference
stoichiometry: 1.0
species: 464314

464314
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: ((N-acetyl-D-glucosaminyl)2-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C50H83N4O35X

477507
type: SpeciesReference
stoichiometry: 1.0
species: 458819

477471
type: SpeciesReference
stoichiometry: 1.0
species: 470652

470652
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646

477459
type: SpeciesReference
stoichiometry: 1.0
species: 464966

464966
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C42H70N3O30X

447129
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: R total 3 position_CO2FULLR3

469939
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Thiamin_C12H17N4OS

445095
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Methoxy-4-hydroxyphenylglycolaldehyde_C9H10O4

458239
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GQ1balpha (homo sapiens)_C88H143N6O54FULLRCO

469721
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: tetracosatetraenoyl coenzyme A_C45H70N7O17P3S

460971
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 33_C76H125N5O62S2

991873
type: Reaction
reactant: 513143
is: http://identifiers.org/ec-code/1.6.5.4
reversible: false
is: ENSBTAG00000015972.3
product: 513179
reactant: 513155
is: ENSBTAG00000038238.1
notes: R_DASCBR subsystem: Ascorbate and Aldarate Metabolism R_DASCBR equation: [c] : dhdascb + h + nadph --> ascb-L + nadp
is: ENSBTAG00000033604.2
is: ENSBTAG00000030454.1
is: ENSBTAG00000038186.1
is: ENSBTAG00000038125.1
product: 513167
fast: false
reactant: 513131
name: dehydroascorbate reductase
is: ENSBTAG00000031256.2

513143
type: SpeciesReference
stoichiometry: 1.0
species: 458794

513179
type: SpeciesReference
stoichiometry: 1.0
species: 449850

449850
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Ascorbate_C6H8O6

513155
type: SpeciesReference
stoichiometry: 1.0
species: 464711

464711
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

513167
type: SpeciesReference
stoichiometry: 1.0
species: 464639

464639
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

513131
type: SpeciesReference
stoichiometry: 1.0
species: 453784

453784
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Dehydroascorbate_C6H6O6

455751
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Fe3+_Fe

451606
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Coenzyme A_C21H32N7O16P3S

457211
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: GDP_C10H12N5O11P2

449681
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: arachidyl carnitine_C27H53NO4

995532
type: Reaction
is: http://identifiers.org/ec-code/4.2.1.49
name: urocanase
notes: R_URCN subsystem: Histidine Metabolism R_URCN equation: [c] : h2o + urcan --> 4izp
is: ENSBTAG00000008774.4
product: 549883
reversible: false
fast: false
reactant: 549859
reactant: 549871

549883
type: SpeciesReference
stoichiometry: 1.0
species: 445721

445721
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-Imidazolone-5-propanoate_C6H7N2O3

549859
type: SpeciesReference
stoichiometry: 1.0
species: 471071

471071
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Urocanate_C6H5N2O2

549871
type: SpeciesReference
stoichiometry: 1.0
species: 458685

992881
type: Reaction
fast: false
is: http://identifiers.org/ec-code/1.1.1.102
product: 524257
product: 524245
notes: R_3DSPHR subsystem: Sphingolipid Metabolism R_3DSPHR equation: [c] : 3dsphgn + h + nadph --> nadp + sphgn
reactant: 524208
name: _3-Dehydrosphinganine reductase
reversible: false
reactant: 524233
reactant: 524221
is: ENSBTAG00000007723.3

524257
type: SpeciesReference
stoichiometry: 1.0
species: 464639

524245
type: SpeciesReference
stoichiometry: 1.0
species: 468827

468827
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Sphinganine_C18H40NO2

524208
type: SpeciesReference
stoichiometry: 1.0
species: 444877

444877
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Dehydrosphinganine_C18H38NO2

524233
type: SpeciesReference
stoichiometry: 1.0
species: 464711

524221
type: SpeciesReference
stoichiometry: 1.0
species: 458794

990228
type: Reaction
reactant: 498887
reversible: false
name: Selenophosphate synthase
product: 498935
fast: false
reactant: 498911
product: 498947
is: ENSBTAG00000010851.4
notes: R_SELNPS subsystem: Selenoamino acid metabolism R_SELNPS equation: [c] : atp + h2o + seln --> amp + pi + selnp
is: ENSBTAG00000008821.3
reactant: 498899
is: http://identifiers.org/ec-code/2.7.9.3
product: 498923

498887
type: SpeciesReference
stoichiometry: 1.0
species: 449983

498935
type: SpeciesReference
stoichiometry: 1.0
species: 468587

468587
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Selenophosphate_H2O3PSe

498911
type: SpeciesReference
stoichiometry: 1.0
species: 458685

498947
type: SpeciesReference
stoichiometry: 1.0
species: 449296

449296
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: AMP_C10H12N5O7P

498899
type: SpeciesReference
stoichiometry: 1.0
species: 468575

468575
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Selenide_HSe

498923
type: SpeciesReference
stoichiometry: 1.0
species: 466736

454234
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S

993674
type: Reaction
is: ENSBTAG00000018245.3
reversible: false
product: 530385
notes: R_GLUt6 subsystem: Transport, Extracellular R_GLUt6 equation: glu-L[e] + h[e] + k[c] + (3) na1[e] --> glu-L[c] + h[c] + k[e] + (3) na1[c] R_ASPDt6 subsystem: Transport, Extracellular R_ASPDt6 equation: asp-D[e] + h[e] + k[c] + (3) na1[e] --> asp-D[c] + h[c] + k[e] + (3) na1[c] R_ASPt6 subsystem: Transport, Extracellular R_ASPt6 equation: asp-L[e] + h[e] + k[c] + (3) na1[e] --> asp-L[c] + h[c] + k[e] + (3) na1[c]
product: 530397
is: ENSBTAG00000019125.4
is: ENSBTAG00000021953.4
is: ENSBTAG00000012628.3
reactant: 530337
product: 530409
is: ENSBTAG00000012516.4
product: 530361
product: 530421
reactant: 530313
fast: false
reactant: 530289
product: 530373
reactant: 530325
reactant: 530301
is: ENSBTAG00000013502.4
reactant: 530349

530385
type: SpeciesReference
stoichiometry: 9.0
species: 464458

464458
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Sodium_Na

530397
type: SpeciesReference
stoichiometry: 1.0
species: 457525

530337
type: SpeciesReference
stoichiometry: 1.0
species: 457537

457537
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Glutamate_C5H8NO4

530409
type: SpeciesReference
stoichiometry: 1.0
species: 449947

449947
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Aspartate_C4H6NO4

530361
type: SpeciesReference
stoichiometry: 3.0
species: 460618

460618
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: potassium_K

530421
type: SpeciesReference
stoichiometry: 3.0
species: 458794

530313
type: SpeciesReference
stoichiometry: 1.0
species: 449959

449959
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Aspartate_C4H6NO4

530289
type: SpeciesReference
stoichiometry: 3.0
species: 458806

458806
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: H+_H

530373
type: SpeciesReference
stoichiometry: 1.0
species: 449911

449911
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Aspartate_C4H6NO4

530325
type: SpeciesReference
stoichiometry: 9.0
species: 464470

464470
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Sodium_Na

530301
type: SpeciesReference
stoichiometry: 3.0
species: 460606

460606
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: potassium_K

530349
type: SpeciesReference
stoichiometry: 1.0
species: 449923

449923
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: D-Aspartate_C4H6NO4

992233
type: Reaction
fast: false
is: ENSBTAG00000003467.3
is: ENSBTAG00000033940.2
product: 518289
is: ENSBTAG00000035124.2
name: inositol transport via sodium symport
reactant: 518265
reversible: true
notes: R_INSTt4_2 subsystem: Transport, Extracellular R_INSTt4_2 equation: inost[e] + (2) na1[e] <==> inost[c] + (2) na1[c]
is: ENSBTAG00000023007.2
is: ENSBTAG00000012851.2
product: 518301
is: ENSBTAG00000003700.4
reactant: 518277
is: ENSBTAG00000008117.4

518289
type: SpeciesReference
stoichiometry: 2.0
species: 464458

518265
type: SpeciesReference
stoichiometry: 2.0
species: 464470

518301
type: SpeciesReference
stoichiometry: 1.0
species: 460425

460425
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: myo-Inositol_C6H12O6

518277
type: SpeciesReference
stoichiometry: 1.0
species: 460437

460437
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: myo-Inositol_C6H12O6

467946
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Pyruvate_C3H3O3

450587
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: cAMP_C10H11N5O6P

995892
type: Reaction
reactant: 553001
reactant: 553062
is: ENSBTAG00000011482.4
product: 553075
reactant: 553050
product: 553087
product: 553099
reactant: 553026
reactant: 553038
notes: R_METtec subsystem: Transport, Extracellular R_METtec equation: met-L[e] <==> met-L[c] R_ILEtec subsystem: Transport, Extracellular R_ILEtec equation: ile-L[e] <==> ile-L[c] R_CYStec subsystem: Transport, Extracellular R_CYStec equation: cys-L[e] <==> cys-L[c] R_LEUtec subsystem: Transport, Extracellular R_LEUtec equation: leu-L[e] <==> leu-L[c] R_VALtec subsystem: Transport, Extracellular R_VALtec equation: val-L[e] <==> val-L[c] R_PHEtec subsystem: Transport, Extracellular R_PHEtec equation: phe-L[e] <==> phe-L[c]
product: 553135
product: 553111
reversible: true
fast: false
product: 553123
reactant: 553013

553001
type: SpeciesReference
stoichiometry: 1.0
species: 462331

462331
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Leucine_C6H13NO2

553062
type: SpeciesReference
stoichiometry: 1.0
species: 466579

466579
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Phenylalanine_C9H11NO2

553075
type: SpeciesReference
stoichiometry: 1.0
species: 452759

452759
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Cysteine_C3H7NO2S

553050
type: SpeciesReference
stoichiometry: 1.0
species: 460303

460303
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Isoleucine_C6H13NO2

553087
type: SpeciesReference
stoichiometry: 1.0
species: 471287

471287
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Valine_C5H11NO2

553099
type: SpeciesReference
stoichiometry: 1.0
species: 460290

460290
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Isoleucine_C6H13NO2

553026
type: SpeciesReference
stoichiometry: 1.0
species: 463842

463842
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Methionine_C5H11NO2S

553038
type: SpeciesReference
stoichiometry: 1.0
species: 471299

471299
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Valine_C5H11NO2

553135
type: SpeciesReference
stoichiometry: 1.0
species: 466567

466567
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Phenylalanine_C9H11NO2

553111
type: SpeciesReference
stoichiometry: 1.0
species: 463830

553123
type: SpeciesReference
stoichiometry: 1.0
species: 462319

462319
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Leucine_C6H13NO2

553013
type: SpeciesReference
stoichiometry: 1.0
species: 452771

452771
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Cysteine_C3H7NO2S

459409
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Homoserine_C4H9NO3

989807
type: Reaction
product: 495368
product: 495416
reactant: 495259
product: 495320
reactant: 495211
product: 495440
product: 495380
reversible: false
notes: R_FUT97g subsystem: Blood Group Biosynthesis R_FUT97g equation: [g] : fuc132galacglcgal14acglcgalgluside_hs + gdpfuc --> fucfuc132galacglcgal14acglcgalgluside_hs + gdp + h R_FUT98g subsystem: Blood Group Biosynthesis R_FUT98g equation: [g] : galacglcgal14acglcgalgluside_hs + gdpfuc --> fuc13galacglcgal14acglcgalgluside_hs + gdp + h R_FUT91g subsystem: Blood Group Biosynthesis R_FUT91g equation: [g] : gal14acglcgalgluside_hs + gdpfuc --> fucgal14acglcgalgluside_hs + gdp + h R_FUT910g subsystem: Blood Group Biosynthesis R_FUT910g equation: [g] : fucgalacglc13galacglcgal14acglcgalgluside_hs + gdpfuc --> fucfucgalacglc13galacglcgal14acglcgalgluside_hs + gdp + h R_FUT95g subsystem: Blood Group Biosynthesis R_FUT95g equation: [g] : fucfucgalacglcgal14acglcgalgluside_hs + gdpfuc --> fucfucfucgalacglcgal14acglcgalgluside_hs + gdp + h R_FUT911g subsystem: Blood Group Biosynthesis R_FUT911g equation: [g] : fucfucgalacglc13galacglcgal14acglcgalgluside_hs + gdpfuc --> fucfucfucgalacglc13galacglcgal14acglcgalgluside_hs + gdp + h R_FUT96g subsystem: Blood Group Biosynthesis R_FUT96g equation: [g] : galacglcgal14acglcgalgluside_hs + gdpfuc --> fuc132galacglcgal14acglcgalgluside_hs + gdp + h R_FUT94g subsystem: Blood Group Biosynthesis R_FUT94g equation: [g] : fucgalacglcgal14acglcgalgluside_hs + gdpfuc --> fucfucgalacglcgal14acglcgalgluside_hs + gdp + h R_FUT92g subsystem: Blood Group Biosynthesis R_FUT92g equation: [g] : acngal14acglcgalgluside_hs + gdpfuc --> fucacngal14acglcgalgluside_hs + gdp + h R_FUT93g subsystem: Blood Group Biosynthesis R_FUT93g equation: [g] : fuc12gal14acglcgalgluside_hs + gdpfuc --> fucfuc12gal14acglcgalgluside_hs + gdp + h R_FUT99g subsystem: Blood Group Biosynthesis R_FUT99g equation: [g] : galacglc13galacglcgal14acglcgalgluside_hs + gdpfuc --> fucgalacglc13galacglcgal14acglcgalgluside_hs + gdp + h
reactant: 495284
reactant: 495247
product: 495392
is: ENSBTAG00000007989.4
product: 495404
product: 495356
product: 495344
reactant: 495272
reactant: 495235
fast: false
reactant: 495174
product: 495428
reactant: 495162
product: 495332
product: 495308
reactant: 495199
is: http://identifiers.org/ec-code/2.4.1.152
reactant: 495187
product: 495296
reactant: 495223

495368
type: SpeciesReference
stoichiometry: 1.0
species: 456221

456221
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)3 (Glc)1 (GlcNAc)2 (LFuc)2 (Cer)1_C70H122N3O40FULLRCO

495416
type: SpeciesReference
stoichiometry: 1.0
species: 456293

456293
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)1 (Cer)1_C78H135N4O46FULLRCO

495259
type: SpeciesReference
stoichiometry: 1.0
species: 456209

456209
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)2 (Cer)1_C84H145N4O50FULLRCO

495320
type: SpeciesReference
stoichiometry: 1.0
species: 456136

456136
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646

495211
type: SpeciesReference
stoichiometry: 1.0
species: 456221

495440
type: SpeciesReference
stoichiometry: 1.0
species: 456172

456172
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646

495380
type: SpeciesReference
stoichiometry: 1.0
species: 456052

456052
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: III3Fuc-nLc6Cer_C64H112N3O36FULLRCO

495284
type: SpeciesReference
stoichiometry: 2.0
species: 456737

456737
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: i-antigen_C58H102N3O32FULLRCO

495247
type: SpeciesReference
stoichiometry: 11.0
species: 457283

457283
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GDP-L-fucose_C16H23N5O15P2

495392
type: SpeciesReference
stoichiometry: 11.0
species: 457223

457223
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GDP_C10H12N5O11P2

495404
type: SpeciesReference
stoichiometry: 1.0
species: 456209

495356
type: SpeciesReference
stoichiometry: 11.0
species: 458819

495344
type: SpeciesReference
stoichiometry: 1.0
species: 456257

456257
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Lacto-N-fucopentaosyl III ceramide_C50H89N2O26FULLRCO

495272
type: SpeciesReference
stoichiometry: 1.0
species: 456293

495235
type: SpeciesReference
stoichiometry: 1.0
species: 456028

456028
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Type IIH glycolipid_C50H89N2O26FULLRCO

495174
type: SpeciesReference
stoichiometry: 1.0
species: 456040

456040
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: V3Fuc-nLc6Cer_C64H112N3O36FULLRCO

495428
type: SpeciesReference
stoichiometry: 1.0
species: 456197

456197
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)3 (Glc)1 (GlcNAc)2 (LFuc)3 (Cer)1_C76H132N3O44FULLRCO

495162
type: SpeciesReference
stoichiometry: 1.0
species: 456641

456641
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646

495332
type: SpeciesReference
stoichiometry: 1.0
species: 456184

456184
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)3 (Cer)1_C90H155N4O54FULLRCO

495308
type: SpeciesReference
stoichiometry: 1.0
species: 456160

456160
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Ley glycolipid_C56H99N2O30FULLRCO

495199
type: SpeciesReference
stoichiometry: 1.0
species: 448232

448232
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646

495187
type: SpeciesReference
stoichiometry: 1.0
species: 456725

456725
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: nLc8Cer_C72H125N4O42FULLRCO

495296
type: SpeciesReference
stoichiometry: 1.0
species: 456040

495223
type: SpeciesReference
stoichiometry: 1.0
species: 456305

456305
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: VI2Fuc-nLc6_C64H112N3O36FULLRCO

454872
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Deoxyuridine_C9H12N2O5

989423
type: Reaction
product: 491886
is: ENSBTAG00000002980.4
reactant: 491862
fast: false
name: L-alanine transaminase
product: 491898
reactant: 491874
notes: R_ALATA_L subsystem: Glutamate metabolism R_ALATA_L equation: [c] : akg + ala-L <==> glu-L + pyr
reversible: true
is: ENSBTAG00000007835.4
is: http://identifiers.org/ec-code/2.6.1.2

491886
type: SpeciesReference
stoichiometry: 1.0
species: 467909

467909
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Pyruvate_C3H3O3

491862
type: SpeciesReference
stoichiometry: 1.0
species: 448946

491898
type: SpeciesReference
stoichiometry: 1.0
species: 457525

491874
type: SpeciesReference
stoichiometry: 1.0
species: 449091

449091
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Alanine_C3H7NO2

448462
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: ADP_C10H12N5O10P2

460157
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Isocitrate_C6H5O7

997770
type: Reaction
product: 572202
product: 572190
reactant: 572178
reversible: false
notes: R_P45046A1r subsystem: Bile Acid Biosynthesis R_P45046A1r equation: [r] : chsterol + h + nadph + o2 --> h2o + nadp + xol24oh
reactant: 572141
product: 572214
name: cytochrome P450, family 46, subfamily A, polypeptide 1
is: ENSBTAG00000038586.1
reactant: 572165
reactant: 572153
fast: false
is: ENSBTAG00000035544.2

572202
type: SpeciesReference
stoichiometry: 1.0
species: 458758

458758
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: H2O_H2O

572190
type: SpeciesReference
stoichiometry: 1.0
species: 471444

471444
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _24-Hydroxycholesterol_C27H46O2

572178
type: SpeciesReference
stoichiometry: 1.0
species: 458867

458867
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: H+_H

572141
type: SpeciesReference
stoichiometry: 1.0
species: 465282

465282
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: O2_O2

572214
type: SpeciesReference
stoichiometry: 1.0
species: 464687

464687
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

572165
type: SpeciesReference
stoichiometry: 1.0
species: 464747

464747
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

572153
type: SpeciesReference
stoichiometry: 1.0
species: 451156

451156
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Cholesterol_C27H46O

452539
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 2_C31H45NO37S4X

452951
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2

456391
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: glucosyl-(alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein)_C70H117N2O55X

987373
type: Reaction
is: ENSBTAG00000033228.1
product: 472970
reactant: 472958
is: http://identifiers.org/ec-code/4.1.3.5
product: 472994
notes: R_HMGCOASi subsystem: Cholesterol Metabolism R_HMGCOASi equation: [c] : aacoa + accoa + h2o --> coa + h + hmgcoa
reactant: 472946
name: Hydroxymethylglutaryl CoA synthase (ir)
reversible: false
is: ENSBTAG00000011839.3
fast: false
product: 472982
reactant: 472934

472970
type: SpeciesReference
stoichiometry: 1.0
species: 451593

451593
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Coenzyme A_C21H32N7O16P3S

472958
type: SpeciesReference
stoichiometry: 1.0
species: 447449

447449
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Acetoacetyl-CoA_C25H36N7O18P3S

472994
type: SpeciesReference
stoichiometry: 1.0
species: 458794

472946
type: SpeciesReference
stoichiometry: 1.0
species: 458685

472982
type: SpeciesReference
stoichiometry: 1.0
species: 459349

459349
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610

472934
type: SpeciesReference
stoichiometry: 1.0
species: 447665

447665
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Acetyl-CoA_C23H34N7O17P3S

451459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: CMP-N-acetylneuraminate_C20H29N4O16P

996217
type: Reaction
reactant: 556972
notes: R_PPCOAOm subsystem: Propanoate Metabolism R_PPCOAOm equation: [m] : fad + ppcoa --> fadh2 + prpncoa R_ACOAD10m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ACOAD10m equation: [m] : 2mbcoa + fad --> 2mb2coa + fadh2 R_ACOAD1fm subsystem: Butanoate Metabolism R_ACOAD1fm equation: [m] : btcoa + fad --> b2coa + fadh2
product: 557020
is: http://identifiers.org/ec-code/1.3.99.12
fast: false
reversible: false
product: 556996
reactant: 556948
is: ENSBTAG00000018041.2
reactant: 556984
product: 557008
reactant: 556960
is: http://identifiers.org/ec-code/1.3.99.3
product: 557032
is: http://identifiers.org/ec-code/1.3.99.2

556972
type: SpeciesReference
stoichiometry: 1.0
species: 466976

466976
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Propanoyl-CoA_C24H36N7O17P3S

557020
type: SpeciesReference
stoichiometry: 1.0
species: 467644

467644
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Propenoyl-CoA_C24H34N7O17P3S

556996
type: SpeciesReference
stoichiometry: 3.0
species: 455618

455618
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

556948
type: SpeciesReference
stoichiometry: 1.0
species: 444527

444527
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _2-Methylbutanoyl-CoA_C26H40N7O17P3S

556984
type: SpeciesReference
stoichiometry: 3.0
species: 455570

455570
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

557008
type: SpeciesReference
stoichiometry: 1.0
species: 444515

444515
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670

556960
type: SpeciesReference
stoichiometry: 1.0
species: 450347

450347
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Butanoyl-CoA_C25H38N7O17P3S

557032
type: SpeciesReference
stoichiometry: 1.0
species: 450055

450055
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Crotonoyl-CoA_C25H36N7O17P3S

991945
type: Reaction
reactant: 514205
reactant: 514341
product: 514571
is: http://identifiers.org/ec-code/1.3.99.3
reactant: 514243
reversible: false
reactant: 514268
reactant: 514097
product: 514523
reactant: 514329
reactant: 514365
notes: R_FAOXC183806m subsystem: Fatty acid oxidation R_FAOXC183806m equation: [m] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC161802m subsystem: Fatty acid activation R_FAOXC161802m equation: [m] : (4) coa + (3) fad + (4) h2o + hdd2coa + (4) nad --> (4) accoa + (3) fadh2 + (4) h + (4) nadh + occoa R_FAOXC160 subsystem: Fatty acid oxidation R_FAOXC160 equation: [m] : (7) coa + (7) fad + (7) h2o + (7) nad + pmtcoa --> (8) accoa + (7) fadh2 + (7) h + (7) nadh R_FAOXC2031836m subsystem: Fatty acid oxidation R_FAOXC2031836m equation: [m] : coa + dlnlcgcoa + fad + h2o + nad --> accoa + fadh2 + h + lnlncgcoa + nadh R_FAOXC80 subsystem: Fatty acid oxidation R_FAOXC80 equation: [m] : (3) coa + (3) fad + (3) h2o + (3) nad + occoa --> (4) accoa + (3) fadh2 + (3) h + (3) nadh R_PPCOAOm subsystem: Propanoate Metabolism R_PPCOAOm equation: [m] : fad + ppcoa --> fadh2 + prpncoa R_FAOXC2251836m subsystem: Fatty acid oxidation R_FAOXC2251836m equation: [m] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_FAOXC18280m subsystem: Fatty acid oxidation R_FAOXC18280m equation: [m] : (5) coa + (3) fad + (5) h2o + lneldccoa + (5) nad --> (5) accoa + (3) fadh2 + (5) h + (5) nadh + occoa R_FAOXC16180m subsystem: Fatty acid oxidation R_FAOXC16180m equation: [m] : (4) coa + (3) fad + (4) h2o + hdcoa + (4) nad --> (4) accoa + (3) fadh2 + (4) h + (4) nadh + occoa R_FAOXC2051843m subsystem: Fatty acid oxidation R_FAOXC2051843m equation: [m] : coa + h2o + nad + tmndnccoa --> accoa + h + nadh + strdnccoa R_FAOXC183803m subsystem: Fatty acid oxidation R_FAOXC183803m equation: [m] : (5) coa + (2) fad + (5) h2o + lnlncacoa + (5) nad --> (5) accoa + (2) fadh2 + (5) h + (5) nadh + occoa R_FAOXC2242046m subsystem: Fatty acid oxidation R_FAOXC2242046m equation: [m] : adrncoa + coa + fad + h2o + nad --> accoa + arachdcoa + fadh2 + h + nadh R_FAOXC200180m subsystem: Fatty acid oxidation R_FAOXC200180m equatio…
product: 514450
reactant: 514293
reactant: 514193
product: 514511
reactant: 514109
reactant: 514181
product: 514547
product: 514402
reactant: 514073
product: 514499
product: 514475
reactant: 514256
reactant: 514169
reactant: 514378
product: 514535
is: http://identifiers.org/ec-code/1.3.99.2
reactant: 514133
reactant: 514281
product: 514426
product: 514438
reactant: 514121
reactant: 514217
fast: false
reactant: 514230
reactant: 514061
product: 514559
product: 514487
reactant: 514157
reactant: 514085
reactant: 514145
reactant: 514049
reactant: 514390
product: 514414
is: ENSBTAG00000007484.2
reactant: 514037
reactant: 514317
product: 514462
reactant: 514353
reactant: 514305

514205
type: SpeciesReference
stoichiometry: 1.0
species: 465633

465633
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Octadecenoyl-CoA (n-C18:1CoA)_C39H64N7O17P3S

514341
type: SpeciesReference
stoichiometry: 2.0
species: 453204

453204
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: docosa-4,7,10,13,16-pentaenoyl coenzyme A_C43H64N7O17P3S

514571
type: SpeciesReference
stoichiometry: 103.0
species: 464602

464602
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

514243
type: SpeciesReference
stoichiometry: 1.0
species: 462635

462635
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: linoelaidyl coenzyme A_C39H62N7O17P3S

514268
type: SpeciesReference
stoichiometry: 1.0
species: 467753

467753
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: pentadecanoyl Coenzyme A_C36H60N7O17P3S

514097
type: SpeciesReference
stoichiometry: 1.0
species: 459109

459109
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Hexadecenoyl-CoA (n-C16:1CoA)_C37H60N7O17P3S

514523
type: SpeciesReference
stoichiometry: 2.0
species: 470192

470192
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: timnodonyl coenzyme A_C41H60N7O17P3S

514329
type: SpeciesReference
stoichiometry: 1.0
species: 469467

469467
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Tetradecanoyl-CoA (n-C14:0CoA)_C35H58N7O17P3S

514365
type: SpeciesReference
stoichiometry: 69.0
species: 455570

514450
type: SpeciesReference
stoichiometry: 2.0
species: 469116

469116
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: stearidonyl coenzyme A_C39H58N7O17P3S

514293
type: SpeciesReference
stoichiometry: 1.0
species: 462695

462695
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: linoleic coenzyme A_C39H62N7O17P3S

514193
type: SpeciesReference
stoichiometry: 1.0
species: 462755

462755
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: alpha-Linolenoyl-CoA_C39H60N7O17P3S

514511
type: SpeciesReference
stoichiometry: 3.0
species: 458649

458649
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Hydrogen peroxide_H2O2

514109
type: SpeciesReference
stoichiometry: 103.0
species: 458733

514181
type: SpeciesReference
stoichiometry: 2.0
species: 450467

450467
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: cervonyl coenzyme A_C43H62N7O17P3S

514547
type: SpeciesReference
stoichiometry: 2.0
species: 462815

462815
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: gamma-linolenoyl-CoA_C39H60N7O17P3S

514402
type: SpeciesReference
stoichiometry: 1.0
species: 469020

469020
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S

514073
type: SpeciesReference
stoichiometry: 2.0
species: 466844

466844
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S

514499
type: SpeciesReference
stoichiometry: 108.0
species: 447689

514475
type: SpeciesReference
stoichiometry: 11.0
species: 465463

465463
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Octanoyl-CoA (n-C8:0CoA)_C29H46N7O17P3S

514256
type: SpeciesReference
stoichiometry: 1.0
species: 470192

514169
type: SpeciesReference
stoichiometry: 1.0
species: 465463

514378
type: SpeciesReference
stoichiometry: 103.0
species: 464542

464542
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

514535
type: SpeciesReference
stoichiometry: 1.0
species: 466976

514133
type: SpeciesReference
stoichiometry: 1.0
species: 455076

455076
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: eicosatetranoyl coenzyme A_C41H62N7O17P3S

514281
type: SpeciesReference
stoichiometry: 1.0
species: 471251

471251
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: vaccenyl coenzyme A_C39H64N7O17P3S

514426
type: SpeciesReference
stoichiometry: 1.0
species: 466844

514438
type: SpeciesReference
stoichiometry: 69.0
species: 455618

514121
type: SpeciesReference
stoichiometry: 1.0
species: 469116

514217
type: SpeciesReference
stoichiometry: 1.0
species: 450347

514230
type: SpeciesReference
stoichiometry: 1.0
species: 459133

459133
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670

514061
type: SpeciesReference
stoichiometry: 1.0
species: 465609

465609
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670

514559
type: SpeciesReference
stoichiometry: 103.0
species: 458843

514487
type: SpeciesReference
stoichiometry: 1.0
species: 450055

514157
type: SpeciesReference
stoichiometry: 1.0
species: 448657

448657
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: adrenyl coenzyme A_C43H66N7O17P3S

514085
type: SpeciesReference
stoichiometry: 1.0
species: 454136

454136
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: dihomo-gamma-linolenyl coenzyme A_C41H64N7O17P3S

514145
type: SpeciesReference
stoichiometry: 1.0
species: 449645

449645
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: arachidyl coenzyme A_C41H70N7O17P3S

514049
type: SpeciesReference
stoichiometry: 1.0
species: 449741

449741
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: C20:4-CoA_C41H62N7O17P3S

514390
type: SpeciesReference
stoichiometry: 3.0
species: 465258

465258
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: O2_O2

514414
type: SpeciesReference
stoichiometry: 1.0
species: 449741

514037
type: SpeciesReference
stoichiometry: 1.0
species: 469020

514317
type: SpeciesReference
stoichiometry: 103.0
species: 451632

514462
type: SpeciesReference
stoichiometry: 1.0
species: 467644

514353
type: SpeciesReference
stoichiometry: 1.0
species: 462815

514305
type: SpeciesReference
stoichiometry: 1.0
species: 466976

466459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Phosphoenolpyruvate_C3H2O6P

460935
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 30_C90H147N6O75S3

445661
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-4-Hydroxyglutamate semialdehyde_C5H9NO4

447286
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: R total carnitine_CO2FULLRC7H14NO2

452624
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Cytosine_C4H5N3O

454367
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Dolichol diphosphate, human uterine homolog_C1025H1670O70P20

450781
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: CDP diacylglycerol (homo sapiens)_C12H17N3O11P2FULLRCO2FULLR2CO2

992953
type: Reaction
reversible: false
reactant: 524631
product: 524655
reactant: 524619
name: malic enzyme (NADP)
fast: false
product: 524643
notes: R_ME2 subsystem: Pyruvate Metabolism R_ME2 equation: [c] : mal-L + nadp --> co2 + nadph + pyr
product: 524667
is: ENSBTAG00000017379.4
is: http://identifiers.org/ec-code/1.1.1.40

524631
type: SpeciesReference
stoichiometry: 1.0
species: 464639

524655
type: SpeciesReference
stoichiometry: 1.0
species: 451519

524619
type: SpeciesReference
stoichiometry: 1.0
species: 463443

524643
type: SpeciesReference
stoichiometry: 1.0
species: 467909

524667
type: SpeciesReference
stoichiometry: 1.0
species: 464711

458396
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: GT3 (homo sapiens)_C63H104N4O36FULLRCO

995220
type: Reaction
is: ENSBTAG00000033414.2
product: 547399
reactant: 547327
reactant: 547291
is: ENSBTAG00000005997.3
is: ENSBTAG00000015666.4
reversible: false
is: ENSBTAG00000005653.4
reactant: 547315
notes: R_CHOLATEt3 subsystem: Transport, Extracellular R_CHOLATEt3 equation: atp[c] + cholate[c] + h2o[c] --> adp[c] + cholate[e] + h[c] + pi[c] R_TCHOLAt3 subsystem: Transport, Extracellular R_TCHOLAt3 equation: atp[c] + h2o[c] + tchola[c] --> adp[c] + h[c] + pi[c] + tchola[e] R_GCHOLAt3 subsystem: Transport, Extracellular R_GCHOLAt3 equation: atp[c] + gchola[c] + h2o[c] --> adp[c] + gchola[e] + h[c] + pi[c]
product: 547351
reactant: 547339
is: ENSBTAG00000026885.3
product: 547411
fast: false
product: 547363
product: 547387
product: 547375
reactant: 547303

547399
type: SpeciesReference
stoichiometry: 1.0
species: 450963

450963
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Cholate_C24H39O5

547327
type: SpeciesReference
stoichiometry: 1.0
species: 450951

450951
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Cholate_C24H39O5

547291
type: SpeciesReference
stoichiometry: 3.0
species: 449983

547315
type: SpeciesReference
stoichiometry: 1.0
species: 457055

457055
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: glycocholate_C26H43NO6

547351
type: SpeciesReference
stoichiometry: 1.0
species: 469395

469395
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: taurocholic acid_C26H45NO7S

547339
type: SpeciesReference
stoichiometry: 3.0
species: 458685

547411
type: SpeciesReference
stoichiometry: 3.0
species: 458794

547363
type: SpeciesReference
stoichiometry: 3.0
species: 466736

547387
type: SpeciesReference
stoichiometry: 3.0
species: 448462

547375
type: SpeciesReference
stoichiometry: 1.0
species: 457067

457067
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: glycocholate_C26H43NO6

547303
type: SpeciesReference
stoichiometry: 1.0
species: 469383

469383
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: taurocholic acid_C26H45NO7S

445986
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5alpha-Dihydrotestosterone_C19H30O2

464398
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: reducing GlcNAc removed form of n2m2nmasn (w/o peptide)_C50H84N4O36

461907
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate II (core 4-linked), degradation product 2_C78H127N6O61S2X

993783
type: Reaction
is: ENSBTAG00000000414.4
product: 531438
product: 531426
notes: R_FUT35g subsystem: Blood Group Biosynthesis R_FUT35g equation: [g] : galfucgalacglcgalgluside_hs + gdpfuc --> fucgalfucgalacglcgalgluside_hs + gdp + h R_FUT31g subsystem: Blood Group Biosynthesis R_FUT31g equation: [g] : galacglcgalgluside_hs + gdpfuc --> fuc14galacglcgalgluside_hs + gdp + h R_FUT34g subsystem: Blood Group Biosynthesis R_FUT34g equation: [g] : fucgalacglcgalgluside_hs + gdpfuc --> fucfucgalacglcgalgluside_hs + gdp + h R_FUT32g subsystem: Blood Group Biosynthesis R_FUT32g equation: [g] : acngalacglcgalgluside_hs + gdpfuc --> fucacngalacglcgalgluside_hs + gdp + h R_FUT33g subsystem: Blood Group Biosynthesis R_FUT33g equation: [g] : acgalfucgalacglcgalgluside_hs + gdpfuc --> fucacgalfucgalacglcgalgluside_hs + gdp + h
reactant: 531352
fast: false
is: http://identifiers.org/ec-code/2.4.1.65
reactant: 531328
product: 531377
reversible: false
reactant: 531316
product: 531364
reactant: 531340
reactant: 531292
product: 531414
product: 531402
product: 531390
reactant: 531304

531438
type: SpeciesReference
stoichiometry: 1.0
species: 456245

456245
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Leb glycolipid_C56H99N2O30FULLRCO

531426
type: SpeciesReference
stoichiometry: 1.0
species: 456329

456329
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)3 (Glc)1 (GlcNAc)1 (LFuc)2 (Cer)1_C62H109N2O35FULLRCO

531352
type: SpeciesReference
stoichiometry: 1.0
species: 447906

447906
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Type IA glycolipid_C58H102N3O31FULLRCO

531328
type: SpeciesReference
stoichiometry: 1.0
species: 448256

448256
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)3 (Glc)1 (GlcNAc)1 (Cer)1_C55H95N3O30FULLRCO

531377
type: SpeciesReference
stoichiometry: 1.0
species: 456124

456124
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)2 (GalNAc)1 (Glc)1 (GlcNAc)1 (LFuc)2 (Cer)1_C64H112N3O35FULLRCO

531316
type: SpeciesReference
stoichiometry: 1.0
species: 456809

456809
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Type IB glycolipid_C56H99N2O31FULLRCO

531364
type: SpeciesReference
stoichiometry: 5.0
species: 458819

531340
type: SpeciesReference
stoichiometry: 5.0
species: 457283

531292
type: SpeciesReference
stoichiometry: 1.0
species: 456317

456317
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Type IH glycolipid_C50H89N2O26FULLRCO

531414
type: SpeciesReference
stoichiometry: 5.0
species: 457223

531402
type: SpeciesReference
stoichiometry: 1.0
species: 456064

456064
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Lea glycolipid_C50H89N2O26FULLRCO

531390
type: SpeciesReference
stoichiometry: 1.0
species: 456148

456148
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646

531304
type: SpeciesReference
stoichiometry: 1.0
species: 456773

456773
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Lc4Cer_C44H79N2O22FULLRCO

462114
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: de-Fuc, reducing GlcNAc removed, de-Sia form of PA6 (w/o peptide linkage)_C54H91N3O41

468695
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-sulfolactate_C3H4O6S

988694
type: Reaction
reactant: 484931
product: 484956
product: 484968
reactant: 484943
reactant: 484919
fast: false
notes: R_ACGAMK subsystem: Aminosugar Metabolism R_ACGAMK equation: [c] : acgam + atp --> acgam6p + adp + h R_AMANK subsystem: Aminosugar Metabolism R_AMANK equation: [c] : acmana + atp --> acmanap + adp + h
reversible: false
is: ENSBTAG00000014668.2
product: 484992
product: 484980
is: http://identifiers.org/ec-code/2.7.1.59
is: http://identifiers.org/ec-code/2.7.1.60

484931
type: SpeciesReference
stoichiometry: 2.0
species: 449983

484956
type: SpeciesReference
stoichiometry: 1.0
species: 448124

448124
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Acetyl-D-mannosamine 6-phosphate_C8H14NO9P

484968
type: SpeciesReference
stoichiometry: 1.0
species: 447931

447931
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Acetyl-D-glucosamine 6-phosphate_C8H14NO9P

484943
type: SpeciesReference
stoichiometry: 1.0
species: 448112

448112
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Acetyl-D-mannosamine_C8H15NO6

484919
type: SpeciesReference
stoichiometry: 1.0
species: 447944

447944
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Acetyl-D-glucosamine_C8H15NO6

484992
type: SpeciesReference
stoichiometry: 2.0
species: 458794

484980
type: SpeciesReference
stoichiometry: 2.0
species: 448462

990996
type: Reaction
product: 505506
reactant: 505458
product: 505482
reactant: 505446
is: ENSBTAG00000000058.4
reactant: 505470
reactant: 505434
product: 505518
product: 505494
reversible: true
fast: false
notes: R_METtec subsystem: Transport, Extracellular R_METtec equation: met-L[e] <==> met-L[c] R_ILEtec subsystem: Transport, Extracellular R_ILEtec equation: ile-L[e] <==> ile-L[c] R_LEUtec subsystem: Transport, Extracellular R_LEUtec equation: leu-L[e] <==> leu-L[c] R_VALtec subsystem: Transport, Extracellular R_VALtec equation: val-L[e] <==> val-L[c]

505506
type: SpeciesReference
stoichiometry: 1.0
species: 463830

505458
type: SpeciesReference
stoichiometry: 1.0
species: 471299

505482
type: SpeciesReference
stoichiometry: 1.0
species: 471287

505446
type: SpeciesReference
stoichiometry: 1.0
species: 463842

505470
type: SpeciesReference
stoichiometry: 1.0
species: 460303

505434
type: SpeciesReference
stoichiometry: 1.0
species: 462331

505518
type: SpeciesReference
stoichiometry: 1.0
species: 462319

505494
type: SpeciesReference
stoichiometry: 1.0
species: 460290

454172
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: demethylated antipyrine_C10H10N2O

993193
type: Reaction
reactant: 526443
notes: R_CITtbm subsystem: Transport, Mitochondrial R_CITtbm equation: cit[c] + pep[m] <==> cit[m] + pep[c] R_CITtam subsystem: Transport, Mitochondrial R_CITtam equation: cit[c] + mal-L[m] <==> cit[m] + mal-L[c]
reactant: 526467
is: ENSBTAG00000008528.4
fast: false
product: 526479
reversible: true
product: 526491
reactant: 526455
product: 526503

526443
type: SpeciesReference
stoichiometry: 1.0
species: 466459

526467
type: SpeciesReference
stoichiometry: 2.0
species: 451217

451217
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Citrate_C6H5O7

526479
type: SpeciesReference
stoichiometry: 2.0
species: 451241

451241
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Citrate_C6H5O7

526491
type: SpeciesReference
stoichiometry: 1.0
species: 466447

466447
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Phosphoenolpyruvate_C3H2O6P

526455
type: SpeciesReference
stoichiometry: 1.0
species: 463455

526503
type: SpeciesReference
stoichiometry: 1.0
species: 463443

450104
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: cis-beta-D-Glucosyl-2-hydroxycinnamate_C15H18O8

460230
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: L-Iduronate_C6H9O7

445516
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _4-Acetamidobutanoate_C6H10NO3

444455
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _2-Deoxy-D-ribose 5-phosphate_C5H9O7P

458576
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Guanidinoacetate_C3H7N3O2

448861
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate_C9H12N5O13P3

469226
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Succinyl-CoA_C25H35N7O19P3S

462222
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: D-Lactaldehyde_C3H6O2

455690
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Formaldehyde_CH2O

449513
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Holocarboxylase (biotin covalent bound to Lys residue of apoC)_C16H27N4O3SX

467304
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: pristanic acid_C19H37O2

463346
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: (alpha-D-Mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1780H2928N20O620P20

466603
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Protoheme_C34H30FeN4O4

470787
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622

993301
type: Reaction
fast: false
product: 527265
product: 527278
is: ENSBTAG00000005002.2
reactant: 527240
notes: R_UDPG4E subsystem: Galactose metabolism R_UDPG4E equation: [c] : udpg <==> udpgal R_UAG4E subsystem: Aminosugar Metabolism R_UAG4E equation: [c] : uacgam <==> udpacgal
is: http://identifiers.org/ec-code/5.1.3.7
is: http://identifiers.org/ec-code/5.1.3.2
reactant: 527252
reversible: true

527265
type: SpeciesReference
stoichiometry: 1.0
species: 470836

470836
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: UDPgalactose_C15H22N2O17P2

527278
type: SpeciesReference
stoichiometry: 1.0
species: 470750

470750
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610

527240
type: SpeciesReference
stoichiometry: 1.0
species: 470800

470800
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: UDPglucose_C15H22N2O17P2

527252
type: SpeciesReference
stoichiometry: 1.0
species: 470640

470640
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610

451671
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Coenzyme A_C21H32N7O16P3S

463019
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: dimannosyl-glucosaminyl-acylphosphatidylinositol (H3)_C43H78NO24PFULLRCO2FULLR2CO2

457682
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Glyoxylate_C2H1O3

993819
type: Reaction
is: ENSBTAG00000017267.3
reactant: 531619
is: ENSBTAG00000008020.2
is: ENSBTAG00000026650.2
is: http://identifiers.org/ec-code/1.9.3.1
is: ENSBTAG00000005096.4
is: ENSBTAG00000040037.1
is: ENSBTAG00000019521.3
is: ENSBTAG00000014878.3
is: ENSBTAG00000030735.2
is: ENSBTAG00000014130.2
is: ENSBTAG00000006530.3
is: ENSBTAG00000009149.1
reactant: 531595
fast: false
reactant: 531607
is: ENSBTAG00000018542.4
is: ENSBTAG00000037415.1
notes: R_CYOOm3 subsystem: Oxidative Phosphorylation R_CYOOm3 equation: (4) focytC[m] + (7.92) h[m] + o2[m] --> (4) ficytC[m] + (4) h[c] + (1.96) h2o[m] + (0.02) o2s[m]
is: ENSBTAG00000000705.2
is: ENSBTAG00000016079.4
is: ENSBTAG00000023487.1
product: 531667
name: cytochrome c oxidase, mitochondrial Complex IV
product: 531655
reversible: false
is: ENSBTAG00000016171.4
is: ENSBTAG00000000003.4
is: ENSBTAG00000034174.1
product: 531643
is: ENSBTAG00000010063.4
product: 531631
is: ENSBTAG00000007200.2

531619
type: SpeciesReference
stoichiometry: 7.92
species: 458843

531595
type: SpeciesReference
stoichiometry: 4.0
species: 455823

455823
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Ferrocytochrome C_C42H54FeN8O6S2

531607
type: SpeciesReference
stoichiometry: 1.0
species: 465258

531667
type: SpeciesReference
stoichiometry: 4.0
species: 458794

531655
type: SpeciesReference
stoichiometry: 4.0
species: 455775

455775
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Ferricytochrome c_C42H54FeN8O6S2

531643
type: SpeciesReference
stoichiometry: 1.0
species: 465331

465331
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Superoxide anion_O2

531631
type: SpeciesReference
stoichiometry: 1.96
species: 458733

444865
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _3-Decaprenyl-4-hydroxybenzoate_C57H85O3

987349
type: Reaction
is: ENSBTAG00000015452.4
reversible: false
name: thioredoxin reductase (NADPH)
fast: false
is: http://identifiers.org/ec-code/1.8.1.9
product: 472872
reactant: 472859
product: 472884
reactant: 472846
notes: R_TRDRm subsystem: Nucleotides R_TRDRm equation: [m] : h + nadph + trdox --> nadp + trdrd
is: ENSBTAG00000011795.4
reactant: 472834

472872
type: SpeciesReference
stoichiometry: 1.0
species: 470288

470288
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Reduced thioredoxin_XH2

472859
type: SpeciesReference
stoichiometry: 1.0
species: 470264

470264
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Oxidized thioredoxin_X

472884
type: SpeciesReference
stoichiometry: 1.0
species: 464663

464663
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

472846
type: SpeciesReference
stoichiometry: 1.0
species: 458843

472834
type: SpeciesReference
stoichiometry: 1.0
species: 464723

464723
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

991020
type: Reaction
product: 505650
reactant: 505638
notes: R_MACACI subsystem: Tyrosine metabolism R_MACACI equation: [c] : 4mlacac --> 4fumacac
is: ENSBTAG00000008538.3
is: http://identifiers.org/ec-code/5.2.1.2
fast: false
reversible: false
name: maleylacetoacetate isomerase

505650
type: SpeciesReference
stoichiometry: 1.0
species: 445601

445601
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-Fumarylacetoacetate_C8H6O6

505638
type: SpeciesReference
stoichiometry: 1.0
species: 445733

445733
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-Maleylacetoacetate_C8H6O6

461994
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II boisynthesis, precursor 2_C47H76N4O33X

989567
type: Reaction
modifier: 493446
fast: false
product: 493410
reactant: 493349
modifier: 493434
reactant: 493336
reactant: 493373
modifier: 493470
product: 493398
reactant: 493361
notes: R_CHOLtu subsystem: Transport, Extracellular R_CHOLtu equation: chol[e] <==> chol[c] R_CRNtuNa subsystem: Transport, Extracellular R_CRNtuNa equation: crn[e] + na1[e] --> crn[c] + na1[c] R_LYSt4 subsystem: Transport, Extracellular R_LYSt4 equation: lys-L[e] + na1[e] --> lys-L[c] + na1[c] R_METt4 subsystem: Transport, Extracellular R_METt4 equation: met-L[e] + na1[e] --> met-L[c] + na1[c] R_CRNt subsystem: Transport, Extracellular R_CRNt equation: crn[e] <==> crn[c]
product: 493386
reversible: false
modifier: 493458
is: ENSBTAG00000000668.4
product: 493422

451900
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Carnitine_C7H15NO3

493410
type: SpeciesReference
stoichiometry: 1.0
species: 451888

451888
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Carnitine_C7H15NO3

493349
type: SpeciesReference
stoichiometry: 1.0
species: 463842

493336
type: SpeciesReference
stoichiometry: 1.0
species: 451900

493373
type: SpeciesReference
stoichiometry: 1.0
species: 462947

462947
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Lysine_C6H15N2O2

450878
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Choline_C5H14NO

493398
type: SpeciesReference
stoichiometry: 3.0
species: 464458

493361
type: SpeciesReference
stoichiometry: 3.0
species: 464470

493386
type: SpeciesReference
stoichiometry: 1.0
species: 462935

462935
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Lysine_C6H15N2O2

450890
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Choline_C5H14NO

493422
type: SpeciesReference
stoichiometry: 1.0
species: 463830

997367
type: Reaction
reversible: true
reactant: 566855
is: ENSBTAG00000018227.4
reactant: 566843
notes: R_HCO3_NAt subsystem: Transport, Extracellular R_HCO3_NAt equation: hco3[e] + na1[e] <==> hco3[c] + na1[c]
product: 566867
fast: false
product: 566879
name: bicarbonate transport (Na/HCO3 cotransport)

566855
type: SpeciesReference
stoichiometry: 1.0
species: 458964

566843
type: SpeciesReference
stoichiometry: 1.0
species: 464470

566867
type: SpeciesReference
stoichiometry: 1.0
species: 458952

566879
type: SpeciesReference
stoichiometry: 1.0
species: 464458

991729
type: Reaction
is: ENSBTAG00000003746.3
product: 511980
product: 511968
product: 511956
reactant: 511871
modifier: 512029
modifier: 512004
fast: false
modifier: 512016
modifier: 511992
reactant: 511908
notes: R_SCP3x subsystem: Bile Acid Biosynthesis R_SCP3x equation: [x] : coa + dhcholestancoa + o2 --> dcholcoa + h2o + ppcoa R_SCPx subsystem: Bile Acid Biosynthesis R_SCPx equation: [x] : cholcoaone + coa --> cholcoa + ppcoa R_SCP21x subsystem: Transport, Peroxisomal R_SCP21x equation: phytcoa[c] <==> phytcoa[x] R_SCP2x subsystem: Bile Acid Biosynthesis R_SCP2x equation: [x] : coa + dhocholoylcoa --> dgcholcoa + ppcoa R_SCP22x subsystem: Transport, Peroxisomal R_SCP22x equation: dmnoncoa[c] <==> dmnoncoa[x]
reactant: 511896
product: 511932
reactant: 511884
reactant: 511920
product: 511944
reversible: false

511980
type: SpeciesReference
stoichiometry: 1.0
species: 453469

453469
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695

511968
type: SpeciesReference
stoichiometry: 3.0
species: 466988

466988
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Propanoyl-CoA_C24H36N7O17P3S

511956
type: SpeciesReference
stoichiometry: 1.0
species: 450975

450975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Choloyl-CoA_C45H70N7O20P3S

511871
type: SpeciesReference
stoichiometry: 1.0
species: 465294

465294
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: O2_O2

466711
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: phytanyl coa_C41H70N7O17P3S

466724
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: phytanyl coa_C41H70N7O17P3S

454221
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S

454246
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S

511908
type: SpeciesReference
stoichiometry: 1.0
species: 453735

453735
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695

511896
type: SpeciesReference
stoichiometry: 1.0
species: 450999

450999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695

511932
type: SpeciesReference
stoichiometry: 1.0
species: 458770

458770
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: H2O_H2O

511884
type: SpeciesReference
stoichiometry: 3.0
species: 451671

511920
type: SpeciesReference
stoichiometry: 1.0
species: 453941

453941
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695

511944
type: SpeciesReference
stoichiometry: 1.0
species: 453132

453132
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: chenodeoxycholoyl coenzyme a_C45H70N7O19P3S

451684
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: cocaine_C17H21NO4

464217
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: (S)-Methylmalonyl-CoA_C25H35N7O19P3S

459769
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: heparan sulfate, degradation product 5_C67H97N4O86S10

469625
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: tetracosapentaenoyl coenzyme A, n-6_C45H68N7O17P3S

460875
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 26_C110H179N7O93S4

461189
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I_C247H393N17O213S12X

448705
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Adrenaline_C9H14NO3

452335
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 3_C37H54NO41S3

454788
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dUDP_C9H11N2O11P2

469298
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: triacylglycerol (homo sapiens)_C3H5FULLRCO2FULLR2CO2FULLR3CO2

446250
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _5-Hydroxyindoleacetate_C10H8NO3

995004
type: Reaction
product: 545636
reactant: 545624
fast: false
is: ENSBTAG00000020498.4
reactant: 545612
reversible: false
name: acid phosphatase (FMN)
notes: R_ACP1_LPAREN_FMN_RPAREN_ subsystem: Riboflavin Metabolism R_ACP1_LPAREN_FMN_RPAREN_ equation: [c] : fmn + h2o --> pi + ribflv
product: 545648
is: http://identifiers.org/ec-code/3.1.3.2
is: ENSBTAG00000008035.4

545636
type: SpeciesReference
stoichiometry: 1.0
species: 468213

468213
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Riboflavin_C17H20N4O6

545624
type: SpeciesReference
stoichiometry: 1.0
species: 458685

545612
type: SpeciesReference
stoichiometry: 1.0
species: 455787

455787
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: FMN_C17H19N4O9P

545648
type: SpeciesReference
stoichiometry: 1.0
species: 466736

455932
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Formyl-CoA_C22H36N7O17P3S

464858
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Ammonium_H4N

455654
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Formaldehyde_CH2O

451277
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Chloride_Cl

990624
type: Reaction
product: 501772
fast: false
notes: R_NORANMT subsystem: Tyrosine metabolism R_NORANMT equation: [c] : amet + nrpphr --> adrnl + ahcys + h
is: http://identifiers.org/ec-code/2.1.1.28
product: 501760
product: 501748
reactant: 501736
name: noradrenaline N-methyltransferase
is: ENSBTAG00000011731.4
reversible: false
reactant: 501724

501772
type: SpeciesReference
stoichiometry: 1.0
species: 458794

501760
type: SpeciesReference
stoichiometry: 1.0
species: 448705

501748
type: SpeciesReference
stoichiometry: 1.0
species: 448813

448813
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

501736
type: SpeciesReference
stoichiometry: 1.0
species: 449236

501724
type: SpeciesReference
stoichiometry: 1.0
species: 465087

465087
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Norepinephrine_C8H12NO3

460739
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 17_C152H245N10O132S7

459854
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: heparan sulfate, precursor 11_C79H121N5O77S4X

467486
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Prostaglandin D2_C20H31O5

449886
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Asparagine_C4H8N2O3

446671
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: heptaglutamyl folate (DHF)_C49H55N13O24

456797
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)4 (Glc)1 (GlcNAc)2 (LFuc)1 (Cer)1_C70H122N3O41FULLRCO

994475
type: Reaction
modifier: 540048
modifier: 539963
modifier: 540181
product: 539915
modifier: 540109
notes: R_ADNt subsystem: Transport, Extracellular R_ADNt equation: adn[e] <==> adn[c] R_INSt subsystem: Transport, Extracellular R_INSt equation: ins[e] <==> ins[c] R_HYXNt subsystem: Transport, Extracellular R_HYXNt equation: hxan[e] <==> hxan[c] R_URIt subsystem: Transport, Extracellular R_URIt equation: uri[e] <==> uri[c] R_GSNt subsystem: Transport, Extracellular R_GSNt equation: gsn[e] <==> gsn[c] R_CSNt subsystem: Transport, Extracellular R_CSNt equation: csn[e] <==> csn[c] R_URAt subsystem: Transport, Extracellular R_URAt equation: ura[e] <==> ura[c] R_ADEt subsystem: Transport, Extracellular R_ADEt equation: ade[e] <==> ade[c] R_GUAt subsystem: Transport, Extracellular R_GUAt equation: gua[e] <==> gua[c] R_THYMt subsystem: Transport, Extracellular R_THYMt equation: thym[e] <==> thym[c] R_THYMDt1 subsystem: Transport, Extracellular R_THYMDt1 equation: thymd[e] --> thymd[c] R_CYTDt subsystem: Transport, Extracellular R_CYTDt equation: cytd[e] <==> cytd[c]
reversible: false
modifier: 540011
modifier: 540121
modifier: 540060
modifier: 539999
modifier: 539975
reactant: 539903
modifier: 540157
fast: false
modifier: 540169
modifier: 539939
modifier: 540072
modifier: 539927
modifier: 539987
modifier: 540023
is: ENSBTAG00000012024.4
modifier: 540145
modifier: 540133
modifier: 539951
modifier: 540097
modifier: 540035
modifier: 540085

458287
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Guanosine_C10H13N5O5

448353
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Adenine_C5H5N5

539915
type: SpeciesReference
stoichiometry: 1.0
species: 470071

470071
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Thymidine_C10H14N2O5

471047
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Uracil_C4H4N2O2

452819
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Cytidine_C9H13N3O5

471119
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Uridine_C9H12N2O6

460059
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Hypoxanthine_C5H4N4O

460047
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Hypoxanthine_C5H4N4O

452611
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Cytosine_C4H5N3O

539903
type: SpeciesReference
stoichiometry: 1.0
species: 470083

470083
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Thymidine_C10H14N2O5

460461
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Inosine_C10H12N4O5

471035
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Uracil_C4H4N2O2

470059
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Thymine_C5H6N2O2

448402
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Adenosine_C10H13N5O4

458552
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Guanine_C5H5N5O

470047
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Thymine_C5H6N2O2

448341
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Adenine_C5H5N5

458299
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Guanosine_C10H13N5O5

448414
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Adenosine_C10H13N5O4

458564
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Guanine_C5H5N5O

452831
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Cytidine_C9H13N3O5

471131
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Uridine_C9H12N2O6

460449
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Inosine_C10H12N4O5

451362
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: clupanodonyl carnitine_C29H47NO4

467801
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Putrescine_C4H14N2

466046
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: phosphatidylinositol 4,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

447677
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Acetyl-CoA_C23H34N7O17P3S

454968
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Erythrose 4-phosphate_C4H7O7P

463503
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Maltose_C12H22O11

468285
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: de-Fuc form of PA6 (w/o peptide linkage)_C84H136N6O62

469890
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: _5,6,7,8-Tetrahydrofolate_C19H21N7O6

997185
type: Reaction
is: ENSBTAG00000006305.3
reactant: 564925
is: ENSBTAG00000016854.4
is: http://identifiers.org/ec-code/2.7.4.3
fast: false
reactant: 564913
product: 564937
name: adenylate kinase
is: ENSBTAG00000037656.1
notes: R_ADK1 subsystem: Nucleotides R_ADK1 equation: [c] : amp + atp <==> (2) adp
reversible: true

564925
type: SpeciesReference
stoichiometry: 1.0
species: 449296

564913
type: SpeciesReference
stoichiometry: 1.0
species: 449983

564937
type: SpeciesReference
stoichiometry: 2.0
species: 448462

445143
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Methylimidazole acetaldehyde_C6H8N2O

987733
type: Reaction
reactant: 476046
product: 476082
reversible: false
reactant: 476021
notes: R_KHK3 subsystem: Galactose metabolism R_KHK3 equation: [c] : atp + tagat-D --> adp + h + tag1p-D R_KHK2 subsystem: Glyoxylate and Dicarboxylate Metabolism R_KHK2 equation: [c] : atp + xylu-D --> adp + h + xu1p-D R_KHK subsystem: Fructose and Mannose Metabolism R_KHK equation: [c] : atp + fru --> adp + f1p + h
reactant: 476009
is: http://identifiers.org/ec-code/2.7.1.3
product: 476058
fast: false
is: ENSBTAG00000011325.4
product: 476094
product: 476107
product: 476070
reactant: 476033

476046
type: SpeciesReference
stoichiometry: 1.0
species: 469323

469323
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Tagatose_C6H12O6

476082
type: SpeciesReference
stoichiometry: 3.0
species: 448462

476021
type: SpeciesReference
stoichiometry: 1.0
species: 456004

456004
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Fructose_C6H12O6

476009
type: SpeciesReference
stoichiometry: 1.0
species: 471842

471842
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Xylulose_C5H10O5

476058
type: SpeciesReference
stoichiometry: 1.0
species: 471781

471781
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Xylulose 1-phosphate_C5H9O8P

476094
type: SpeciesReference
stoichiometry: 1.0
species: 455509

455509
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Fructose 1-phosphate_C6H11O9P

476107
type: SpeciesReference
stoichiometry: 3.0
species: 458794

476070
type: SpeciesReference
stoichiometry: 1.0
species: 469286

469286
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Tagatose 1-phosphate_C6H11O9P

476033
type: SpeciesReference
stoichiometry: 3.0
species: 449983

456475
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: (alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1900H3128N20O720P20

453384
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Dodecanoyl-CoA (n-C12:0CoA)_C33H54N7O17P3S

452407
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 3_C37H53NO40S3X

W3 CDTF: Thu Aug 12 17:10:28 BST 2010

988166
type: Reaction
is: http://identifiers.org/ec-code/5.1.3.14
fast: false
reactant: 479938
reactant: 479926
product: 479974
reactant: 479950
product: 480010
product: 479986
is: http://identifiers.org/ec-code/2.7.1.60
product: 480022
reversible: false
product: 479998
reactant: 479962
notes: R_UAG2EMAi subsystem: Aminosugar Metabolism R_UAG2EMAi equation: [c] : h2o + uacgam --> acmana + h + udp R_AMANK subsystem: Aminosugar Metabolism R_AMANK equation: [c] : acmana + atp --> acmanap + adp + h
is: ENSBTAG00000001142.3

479938
type: SpeciesReference
stoichiometry: 1.0
species: 448112

479926
type: SpeciesReference
stoichiometry: 1.0
species: 470640

479974
type: SpeciesReference
stoichiometry: 1.0
species: 448124

479950
type: SpeciesReference
stoichiometry: 1.0
species: 449983

480010
type: SpeciesReference
stoichiometry: 1.0
species: 448112

479986
type: SpeciesReference
stoichiometry: 1.0
species: 448462

480022
type: SpeciesReference
stoichiometry: 2.0
species: 458794

479998
type: SpeciesReference
stoichiometry: 1.0
species: 470664

470664
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: UDP_C9H11N2O12P2

479962
type: SpeciesReference
stoichiometry: 1.0
species: 458685

444045
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1,3-Diaminopropane_C3H12N2

465730
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: D-Ornithine_C5H13N2O2

987277
type: Reaction
product: 472025
is: http://identifiers.org/ec-code/3.1.1.23
product: 472049
reversible: false
fast: false
name: lipase
reactant: 472001
reactant: 472013
is: ENSBTAG00000018248.4
notes: R_LPS3 subsystem: Triacylglycerol Synthesis R_LPS3 equation: [c] : h2o + mag_hs --> Rtotal2 + glyc + h
product: 472037

472025
type: SpeciesReference
stoichiometry: 1.0
species: 447057

447057
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: R total 2 position_CO2FULLR2

472049
type: SpeciesReference
stoichiometry: 1.0
species: 457852

457852
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Glycerol_C3H8O3

472001
type: SpeciesReference
stoichiometry: 1.0
species: 463395

463395
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: monoacylglycerol 2 (homo sapiens)_C3H7O2FULLR2CO2

472013
type: SpeciesReference
stoichiometry: 1.0
species: 458685

472037
type: SpeciesReference
stoichiometry: 1.0
species: 458794

991188
type: Reaction
is: http://identifiers.org/ec-code/2.7.1.48
reactant: 507127
product: 507199
reversible: false
product: 507175
reactant: 507151
notes: R_URIK1 subsystem: Pyrimidine Biosynthesis R_URIK1 equation: [c] : atp + uri --> adp + h + ump R_CYTDK1 subsystem: Nucleotides R_CYTDK1 equation: [c] : atp + cytd --> adp + cmp + h
is: ENSBTAG00000010810.4
fast: false
product: 507187
product: 507163
reactant: 507139

507127
type: SpeciesReference
stoichiometry: 2.0
species: 449983

507199
type: SpeciesReference
stoichiometry: 2.0
species: 458794

507175
type: SpeciesReference
stoichiometry: 1.0
species: 470936

470936
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: UMP_C9H11N2O9P

507151
type: SpeciesReference
stoichiometry: 1.0
species: 471119

507187
type: SpeciesReference
stoichiometry: 2.0
species: 448462

507163
type: SpeciesReference
stoichiometry: 1.0
species: 451398

451398
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: CMP_C9H12N3O8P

507139
type: SpeciesReference
stoichiometry: 1.0
species: 452819

450756
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: CDP_C9H12N3O11P2

989495
type: Reaction
product: 492845
product: 492870
notes: R_FE3R2e subsystem: Heme Biosynthesis R_FE3R2e equation: [e] : ascb-L + (2) fe3 --> dhdascb + (2) fe2 + (2) h
is: ENSBTAG00000007898.3
reversible: false
name: Fe(III) reduction (ascorbate)
reactant: 492832
product: 492857
reactant: 492819
fast: false

492845
type: SpeciesReference
stoichiometry: 2.0
species: 458806

492870
type: SpeciesReference
stoichiometry: 2.0
species: 455727

455727
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Fe2+_Fe

492832
type: SpeciesReference
stoichiometry: 1.0
species: 449862

449862
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Ascorbate_C6H8O6

492857
type: SpeciesReference
stoichiometry: 1.0
species: 453796

453796
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Dehydroascorbate_C6H6O6

492819
type: SpeciesReference
stoichiometry: 2.0
species: 455751

445323
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Phospho-D-glycerate_C3H4O7P

467897
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Perillyl aldehyde_C10H14O

465864
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

462779
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: alpha-linolenyl carnitine_C25H43NO4

444647
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3,4-Dihydroxymandelate_C8H7O5

996723
type: Reaction
reactant: 561095
product: 561107
notes: R_DUTPDPn subsystem: Nucleotides R_DUTPDPn equation: [n] : dutp + h2o --> dump + h + ppi R_DUTPDPm subsystem: Nucleotides R_DUTPDPm equation: [m] : dutp + h2o --> dump + h + ppi
product: 561155
is: http://identifiers.org/ec-code/3.6.1.23
product: 561167
product: 561131
reversible: false
product: 561143
reactant: 561070
fast: false
product: 561119
reactant: 561083
reactant: 561058
is: ENSBTAG00000011998.4

561095
type: SpeciesReference
stoichiometry: 1.0
species: 458746

458746
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: H2O_H2O

561107
type: SpeciesReference
stoichiometry: 1.0
species: 454848

454848
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: dUMP_C9H11N2O8P

561155
type: SpeciesReference
stoichiometry: 1.0
species: 467012

467012
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Diphosphate_HO7P2

561167
type: SpeciesReference
stoichiometry: 1.0
species: 458843

561131
type: SpeciesReference
stoichiometry: 1.0
species: 467024

467024
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Diphosphate_HO7P2

561143
type: SpeciesReference
stoichiometry: 1.0
species: 454836

454836
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: dUMP_C9H11N2O8P

561070
type: SpeciesReference
stoichiometry: 1.0
species: 454920

454920
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: dUTP_C9H11N2O14P3

561119
type: SpeciesReference
stoichiometry: 1.0
species: 458855

458855
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: H+_H

561083
type: SpeciesReference
stoichiometry: 1.0
species: 454908

454908
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: dUTP_C9H11N2O14P3

561058
type: SpeciesReference
stoichiometry: 1.0
species: 458733

992857
type: Reaction
is: ENSBTAG00000039095.1
product: 524046
reactant: 524010
notes: R_NRPPHRt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_NRPPHRt4_LPAREN_2_RPAREN_r equation: (2) na1[e] + nrpphr[e] <==> (2) na1[c] + nrpphr[c] R_DOPAt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_DOPAt4_LPAREN_2_RPAREN_r equation: dopa[e] + (2) na1[e] <==> dopa[c] + (2) na1[c]
product: 524059
fast: false
reversible: true
reactant: 523998
is: ENSBTAG00000003353.4
reactant: 524022
is: ENSBTAG00000015843.4
product: 524034

524046
type: SpeciesReference
stoichiometry: 4.0
species: 464458

524010
type: SpeciesReference
stoichiometry: 4.0
species: 464470

524059
type: SpeciesReference
stoichiometry: 1.0
species: 454523

454523
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Dopamine_C8H12NO2

523998
type: SpeciesReference
stoichiometry: 1.0
species: 454535

454535
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Dopamine_C8H12NO2

524022
type: SpeciesReference
stoichiometry: 1.0
species: 465099

465099
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Norepinephrine_C8H12NO3

524034
type: SpeciesReference
stoichiometry: 1.0
species: 465087

471083
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Urea_CH4N2O

448765
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _3alpha-Hydroxy-5beta-androstan-17-one_C19H30O2

460474
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Inosine_C10H12N4O5

987805
type: Reaction
product: 476677
reactant: 476641
is: ENSBTAG00000035287.1
product: 476653
product: 476749
reactant: 476616
reactant: 476568
product: 476737
reactant: 476592
reversible: false
reactant: 476580
notes: R_HSD3B3r subsystem: Steroid Metabolism R_HSD3B3r equation: [r] : eandrstrn + h + nadph --> andrstandn + h2o + nadp R_HSD3B2r subsystem: Steroid Metabolism R_HSD3B2r equation: [r] : eandrstrn + h + nadh --> andrstandn + h2o + nad R_HSD3B11r subsystem: Steroid Metabolism R_HSD3B11r equation: [r] : nad + prgnlone --> h + nadh + prgstrn R_HSD3B12r subsystem: Steroid Metabolism R_HSD3B12r equation: [r] : dhea + nad --> andrstndn + h + nadh R_HSD3B13r subsystem: Steroid Metabolism R_HSD3B13r equation: [r] : 17ahprgnlone + nad --> 17ahprgstrn + h + nadh
is: ENSBTAG00000014724.3
product: 476725
product: 476689
fast: false
product: 476713
reactant: 476628
reactant: 476604
reactant: 476556
product: 476701
product: 476665

476677
type: SpeciesReference
stoichiometry: 1.0
species: 467279

467279
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Progesterone_C21H30O2

476641
type: SpeciesReference
stoichiometry: 2.0
species: 454992

454992
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: epiandrosterone_C19H28O3

476653
type: SpeciesReference
stoichiometry: 2.0
species: 458758

476749
type: SpeciesReference
stoichiometry: 1.0
species: 444117

444117
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _17alpha-Hydroxyprogesterone_C21H30O3

476616
type: SpeciesReference
stoichiometry: 2.0
species: 458867

476568
type: SpeciesReference
stoichiometry: 1.0
species: 464747

476737
type: SpeciesReference
stoichiometry: 3.0
species: 464615

464615
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

476592
type: SpeciesReference
stoichiometry: 3.0
species: 464566

464566
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

476580
type: SpeciesReference
stoichiometry: 1.0
species: 444093

444093
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _17alpha-Hydroxypregnenolone_C21H32O3

476725
type: SpeciesReference
stoichiometry: 3.0
species: 458867

476689
type: SpeciesReference
stoichiometry: 1.0
species: 449393

449393
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Androstenedione_C19H26O2

476713
type: SpeciesReference
stoichiometry: 1.0
species: 464566

476628
type: SpeciesReference
stoichiometry: 1.0
species: 464615

476604
type: SpeciesReference
stoichiometry: 1.0
species: 453820

453820
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Dehydroepiandrosterone_C19H28O2

476556
type: SpeciesReference
stoichiometry: 1.0
species: 467231

467231
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Pregnenolone_C21H32O2

476701
type: SpeciesReference
stoichiometry: 1.0
species: 464687

476665
type: SpeciesReference
stoichiometry: 2.0
species: 449381

449381
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: androstanedione_C19H28O2

455594
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

991332
type: Reaction
fast: false
reactant: 508529
is: ENSBTAG00000006066.4
reactant: 508505
product: 508541
is: http://identifiers.org/ec-code/2.7.7.41
notes: R_CDSm subsystem: Glycerophospholipid Metabolism R_CDSm equation: [m] : ctp + h + pa_hs --> cdpdag_hs + ppi
product: 508553
reactant: 508517
reversible: false
name: phosphatidate cytidylyltransferase

508529
type: SpeciesReference
stoichiometry: 1.0
species: 458843

508505
type: SpeciesReference
stoichiometry: 1.0
species: 465864

508541
type: SpeciesReference
stoichiometry: 1.0
species: 450793

450793
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: CDP diacylglycerol (homo sapiens)_C12H17N3O11P2FULLRCO2FULLR2CO2

508553
type: SpeciesReference
stoichiometry: 1.0
species: 467012

508517
type: SpeciesReference
stoichiometry: 1.0
species: 452709

452709
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: CTP_C9H12N3O14P3

457151
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GD2 (homo sapiens)_C60H101N4O33FULLRCO

990408
type: Reaction
reactant: 500157
is: ENSBTAG00000004995.3
fast: false
is: http://identifiers.org/ec-code/2.4.1.122
product: 500181
reversible: false
product: 500205
reactant: 500169
product: 500193
notes: R_N3Tg subsystem: O-Glycan Biosynthesis R_N3Tg equation: [g] : Tn_antigen + udpgal --> T_antigen + h + udp
name: N-acetylgalactosamine 3-beta-galactosyltransferase, Golgi apparatus

500157
type: SpeciesReference
stoichiometry: 1.0
species: 470848

500181
type: SpeciesReference
stoichiometry: 1.0
species: 470688

500205
type: SpeciesReference
stoichiometry: 1.0
species: 447387

447387
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: T antigen (core 1)_C14H24NO10X

500169
type: SpeciesReference
stoichiometry: 1.0
species: 447400

447400
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Tn antigen_C8H14NO5X

500193
type: SpeciesReference
stoichiometry: 1.0
species: 458819

455992
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Farnesyl diphosphate_C15H25O7P2

451507
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _2-Amino-3-carboxymuconate semialdehyde_C7H6NO5

452178
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate B (IdoA2S-GalNAc4S), precursor 4_C45H67N2O42S2X

469407
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: taurocholic acid_C26H45NO7S

459157
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: trans-Hexadec-2-enoyl carnitine_C23H43NO4

463032
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: (alpha-D-mannosyl)2-beta-D-mannosyl-N-acetylglucosamine_C26H45NO21

988466
type: Reaction
reversible: false
product: 482500
is: ENSBTAG00000016740.4
name: ATP-Citrate lyase
product: 482524
fast: false
notes: R_ACITL subsystem: Citric Acid Cycle R_ACITL equation: [c] : atp + cit + coa --> accoa + adp + oaa + pi
product: 482512
reactant: 482464
product: 482536
reactant: 482488
reactant: 482476

482500
type: SpeciesReference
stoichiometry: 1.0
species: 448462

482524
type: SpeciesReference
stoichiometry: 1.0
species: 466736

482512
type: SpeciesReference
stoichiometry: 1.0
species: 465367

465367
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Oxaloacetate_C4H2O5

482464
type: SpeciesReference
stoichiometry: 1.0
species: 451593

482536
type: SpeciesReference
stoichiometry: 1.0
species: 447665

482488
type: SpeciesReference
stoichiometry: 1.0
species: 449983

482476
type: SpeciesReference
stoichiometry: 1.0
species: 451217

W3 CDTF: Fri Feb 03 12:44:18 GMT 2012

994848
type: Reaction
product: 544495
reactant: 544375
product: 544471
reactant: 544447
reactant: 544435
reactant: 544399
reactant: 544387
is: http://identifiers.org/ec-code/2.7.4.3
reversible: true
product: 544459
product: 544483
product: 544507
fast: false
is: ENSBTAG00000017411.4
notes: R_ADK1 subsystem: Nucleotides R_ADK1 equation: [c] : amp + atp <==> (2) adp R_ADK3 subsystem: Nucleotides R_ADK3 equation: [c] : amp + gtp <==> adp + gdp R_CYTK4 subsystem: Nucleotides R_CYTK4 equation: [c] : dcmp + gtp <==> dcdp + gdp R_CYTK3 subsystem: Nucleotides R_CYTK3 equation: [c] : cmp + gtp <==> cdp + gdp R_ADKd subsystem: Nucleotides R_ADKd equation: [c] : damp + datp <==> (2) dadp
reactant: 544411
reactant: 544423

544495
type: SpeciesReference
stoichiometry: 1.0
species: 453096

453096
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dCDP_C9H12N3O10P2

544375
type: SpeciesReference
stoichiometry: 1.0
species: 451398

544471
type: SpeciesReference
stoichiometry: 2.0
species: 452915

452915
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dADP_C10H12N5O9P2

544447
type: SpeciesReference
stoichiometry: 1.0
species: 453144

453144
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dCMP_C9H12N3O7P

544435
type: SpeciesReference
stoichiometry: 2.0
species: 449296

544399
type: SpeciesReference
stoichiometry: 1.0
species: 453023

453023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dATP_C10H12N5O12P3

544387
type: SpeciesReference
stoichiometry: 1.0
species: 449983

544459
type: SpeciesReference
stoichiometry: 3.0
species: 457199

457199
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: GDP_C10H12N5O11P2

544483
type: SpeciesReference
stoichiometry: 3.0
species: 448462

544507
type: SpeciesReference
stoichiometry: 1.0
species: 450732

450732
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: CDP_C9H12N3O11P2

544411
type: SpeciesReference
stoichiometry: 3.0
species: 458504

458504
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: GTP_C10H12N5O14P3

544423
type: SpeciesReference
stoichiometry: 1.0
species: 452999

452999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dAMP_C10H12N5O6P

993349
type: Reaction
reactant: 527653
is: ENSBTAG00000000111.4
notes: R_GALU subsystem: Galactose metabolism R_GALU equation: [c] : g1p + h + utp <==> ppi + udpg
is: http://identifiers.org/ec-code/2.7.7.9
reversible: true
reactant: 527628
fast: false
name: UTP-glucose-1-phosphate uridylyltransferase
product: 527678
product: 527666
reactant: 527641

527653
type: SpeciesReference
stoichiometry: 1.0
species: 471179

471179
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: UTP_C9H11N2O15P3

527628
type: SpeciesReference
stoichiometry: 1.0
species: 456451

527678
type: SpeciesReference
stoichiometry: 1.0
species: 467000

527666
type: SpeciesReference
stoichiometry: 1.0
species: 470800

527641
type: SpeciesReference
stoichiometry: 1.0
species: 458794

989603
type: Reaction
reversible: false
product: 493794
is: ENSBTAG00000000033.3
product: 493819
reactant: 493770
reactant: 493782
notes: R_CHLP subsystem: Glycerophospholipid Metabolism R_CHLP equation: [c] : cholp + h2o --> chol + pi R_ETHP subsystem: Glycerophospholipid Metabolism R_ETHP equation: [c] : ethamp + h2o --> etha + pi
reactant: 493758
fast: false
product: 493806
is: http://identifiers.org/ec-code/2.7.7.15

493794
type: SpeciesReference
stoichiometry: 1.0
species: 455436

455436
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Ethanolamine_C2H8NO

493819
type: SpeciesReference
stoichiometry: 1.0
species: 450878

493770
type: SpeciesReference
stoichiometry: 1.0
species: 451060

451060
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Choline phosphate_C5H13NO4P

493782
type: SpeciesReference
stoichiometry: 2.0
species: 458685

493758
type: SpeciesReference
stoichiometry: 1.0
species: 455448

455448
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Ethanolamine phosphate_C2H7NO4P

493806
type: SpeciesReference
stoichiometry: 2.0
species: 466736

458118
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: GMP_C10H12N5O8P

987745
type: Reaction
fast: false
reactant: 476131
reactant: 476119
product: 476191
reactant: 476143
notes: R_ACCOALm subsystem: Propanoate Metabolism R_ACCOALm equation: [m] : atp + coa + ppa --> amp + ppcoa + ppi R_ACSm subsystem: Glycolysis/Gluconeogenesis R_ACSm equation: [m] : ac + atp + coa --> accoa + amp + ppi
reactant: 476155
product: 476179
is: http://identifiers.org/ec-code/6.2.1.17
reversible: false
is: http://identifiers.org/ec-code/6.2.1.1
product: 476167
product: 476204
is: ENSBTAG00000004281.4

476131
type: SpeciesReference
stoichiometry: 1.0
species: 447557

447557
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Acetate_C2H3O2

476119
type: SpeciesReference
stoichiometry: 1.0
species: 466940

466940
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Propionate (n-C3:0)_C3H5O2

476191
type: SpeciesReference
stoichiometry: 2.0
species: 449344

476143
type: SpeciesReference
stoichiometry: 2.0
species: 451632

476155
type: SpeciesReference
stoichiometry: 2.0
species: 450007

450007
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: ATP_C10H12N5O13P3

476179
type: SpeciesReference
stoichiometry: 1.0
species: 466976

476167
type: SpeciesReference
stoichiometry: 1.0
species: 447689

476204
type: SpeciesReference
stoichiometry: 2.0
species: 467012

449079
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: D-Alanine_C3H7NO2

993831
type: Reaction
product: 531752
product: 531788
notes: R_SUCOASm subsystem: Citric Acid Cycle R_SUCOASm equation: [m] : atp + coa + succ <==> adp + pi + succoa R_MECOALm subsystem: C5-Branched dibasic acid metabolism R_MECOALm equation: [m] : atp + coa + mescon <==> adp + mescoa + pi R_ITCOALm subsystem: C5-Branched dibasic acid metabolism R_ITCOALm equation: [m] : atp + coa + itacon <==> adp + itaccoa + pi
is: ENSBTAG00000034357.1
reactant: 531715
reactant: 531679
fast: false
product: 531739
reactant: 531703
reactant: 531727
product: 531764
is: http://identifiers.org/ec-code/6.2.1.5
reactant: 531691
is: ENSBTAG00000006759.4
product: 531776
reversible: true

531752
type: SpeciesReference
stoichiometry: 1.0
species: 469226

531788
type: SpeciesReference
stoichiometry: 3.0
species: 448486

531715
type: SpeciesReference
stoichiometry: 3.0
species: 450007

531679
type: SpeciesReference
stoichiometry: 1.0
species: 463818

463818
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Mesaconate_C5H4O4

531739
type: SpeciesReference
stoichiometry: 1.0
species: 460534

460534
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Itaconyl-CoA_C26H35N7O19P3S

531703
type: SpeciesReference
stoichiometry: 3.0
species: 451632

531727
type: SpeciesReference
stoichiometry: 1.0
species: 460546

531764
type: SpeciesReference
stoichiometry: 1.0
species: 463805

463805
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Mesaconyl-CoA_C26H35N7O19P3S

531691
type: SpeciesReference
stoichiometry: 1.0
species: 469190

469190
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Succinate_C4H4O4

531776
type: SpeciesReference
stoichiometry: 3.0
species: 466784

466784
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Phosphate_HO4P

989963
type: Reaction
product: 496319
product: 496307
reactant: 496295
is: http://identifiers.org/ec-code/4.99.1.1
reversible: false
name: Ferrochelatase, mitochondrial
is: ENSBTAG00000015188.3
reactant: 496283
notes: R_FCLTm subsystem: Heme Biosynthesis R_FCLTm equation: [m] : fe2 + ppp9 --> (2) h + pheme
fast: false

496319
type: SpeciesReference
stoichiometry: 2.0
species: 458843

496307
type: SpeciesReference
stoichiometry: 1.0
species: 466627

466627
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Protoheme_C34H30FeN4O4

496295
type: SpeciesReference
stoichiometry: 1.0
species: 455739

455739
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Fe2+_Fe

496283
type: SpeciesReference
stoichiometry: 1.0
species: 467110

467110
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Protoporphyrin_C34H32N4O4

469092
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: stearidonic acid C18:4, n-3_C18H27O2

453759
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695

454148
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dihomo-gamma-linolenyl carnitine_C27H47NO4

469817
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate_C27H45O5

991741
type: Reaction
product: 512077
notes: R_PGPPT subsystem: Glycerophospholipid Metabolism R_PGPPT equation: [c] : cdpdag_hs + glyc3p --> cmp + h + pgp_hs
product: 512065
reversible: false
fast: false
name: phosphatidyl-CMP: glycerophosphate phosphatidyltransferase
is: ENSBTAG00000000675.4
product: 512089
is: http://identifiers.org/ec-code/2.7.8.11
reactant: 512053
reactant: 512041

512077
type: SpeciesReference
stoichiometry: 1.0
species: 451398

512065
type: SpeciesReference
stoichiometry: 1.0
species: 466555

466555
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: phosphatidyl glycerol phosphate (homo sapiens)_C6H11O9P2FULLRCO2FULLR2CO2

512089
type: SpeciesReference
stoichiometry: 1.0
species: 458794

512053
type: SpeciesReference
stoichiometry: 1.0
species: 450781

512041
type: SpeciesReference
stoichiometry: 1.0
species: 457804

457804
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Glycerol 3-phosphate_C3H7O6P

450395
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Biotin_C10H15N2O3S

997081
type: Reaction
product: 564542
is: ENSBTAG00000011226.4
reactant: 564518
name: bicarbonate transport (Cl-/HCO3- exchange)
is: ENSBTAG00000001610.4
notes: R_HCO3_CLt subsystem: Transport, Extracellular R_HCO3_CLt equation: cl[c] + hco3[e] <==> cl[e] + hco3[c]
fast: false
is: ENSBTAG00000014975.4
reversible: true
is: ENSBTAG00000021775.4
product: 564554
reactant: 564530

564542
type: SpeciesReference
stoichiometry: 1.0
species: 458952

564518
type: SpeciesReference
stoichiometry: 1.0
species: 451277

564554
type: SpeciesReference
stoichiometry: 1.0
species: 451289

451289
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Chloride_Cl

564530
type: SpeciesReference
stoichiometry: 1.0
species: 458964

454595
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Deoxyribose_C5H10O4

459337
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Hydroxymethylbilane_C40H38N4O17

997172
type: Reaction
product: 564901
reactant: 564889
notes: R_PHEMEt subsystem: Transport, Extracellular R_PHEMEt equation: pheme[e] --> pheme[c]
is: ENSBTAG00000002817.4
fast: false
reversible: false
name: heme transport

564901
type: SpeciesReference
stoichiometry: 1.0
species: 466603

564889
type: SpeciesReference
stoichiometry: 1.0
species: 466615

466615
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Protoheme_C34H30FeN4O4

461044
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 39_C48H81N3O36

995400
type: Reaction
product: 548869
reactant: 548842
fast: false
is: ENSBTAG00000007415.4
name: L-cysteine/glycine exchanger
notes: R_CYSGLYex subsystem: Transport, Extracellular R_CYSGLYex equation: cys-L[c] + gly[e] --> cys-L[e] + gly[c]
reactant: 548856
product: 548882
reversible: false

548869
type: SpeciesReference
stoichiometry: 1.0
species: 457707

457707
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Glycine_C2H5NO2

548842
type: SpeciesReference
stoichiometry: 1.0
species: 452759

548856
type: SpeciesReference
stoichiometry: 1.0
species: 457719

457719
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Glycine_C2H5NO2

548882
type: SpeciesReference
stoichiometry: 1.0
species: 452771

468719
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Sulfite_O3S

445480
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4,6-Dihydroxyquinoline_C9H7NO2

465124
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: nervonic acid_C24H45O2

452021
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate A (GalNAc4S-GlcA), B (IdoA2S-GalNAc4S), and E (GalNAc4,6diS-GlcA), precursor 1_C31H47NO31S2X

471155
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Uridine_C9H12N2O6

451132
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Cholesterol_C27H46O

993373
type: Reaction
reactant: 527762
is: http://identifiers.org/ec-code/1.14.16.4
reactant: 527750
is: ENSBTAG00000005343.4
reversible: false
notes: R_TRPHYDRO2 subsystem: Tryptophan metabolism R_TRPHYDRO2 equation: [c] : o2 + thbpt + trp-L --> 5htrp + thbpt4acam
fast: false
is: ENSBTAG00000020792.4
product: 527787
name: L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)
reactant: 527738
product: 527775

527762
type: SpeciesReference
stoichiometry: 1.0
species: 465234

527750
type: SpeciesReference
stoichiometry: 1.0
species: 470361

470361
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Tryptophan_C11H12N2O2

527787
type: SpeciesReference
stoichiometry: 1.0
species: 446274

446274
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-Hydroxy-L-tryptophan_C11H12N2O3

527738
type: SpeciesReference
stoichiometry: 1.0
species: 469769

469769
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Tetrahydrobiopterin_C9H15N5O3

527775
type: SpeciesReference
stoichiometry: 1.0
species: 469757

469757
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Tetrahydrobiopterin-4a-carbinolamine_C9H15N5O4

471588
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _7alpha,12alpha-Dihydroxycholest-4-en-3-one_C27H44O3

465670
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: octadecenoyl carnitine_C25H47NO4

444382
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: cis-2-Hydroxy cinnamate_C9H7O3

456909
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: galactocerebroside (homo sapiens)_C24H46NO7FULLRCO

451744
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Core 6_C16H27N2O10X

992293
type: Reaction
name: NAD synthase (glutamine-hydrolysing)
reversible: false
reactant: 518604
is: http://identifiers.org/ec-code/6.3.5.1
is: ENSBTAG00000016470.3
reactant: 518592
notes: R_NADS2 subsystem: NAD Metabolism R_NADS2 equation: [c] : atp + dnad + gln-L + h2o --> amp + glu-L + h + nad + ppi
product: 518664
product: 518640
reactant: 518568
fast: false
product: 518652
product: 518616
product: 518628
reactant: 518580

518604
type: SpeciesReference
stoichiometry: 1.0
species: 454318

454318
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Deamino-NAD+_C21H24N6O15P2

518592
type: SpeciesReference
stoichiometry: 1.0
species: 458685

518664
type: SpeciesReference
stoichiometry: 1.0
species: 467000

518640
type: SpeciesReference
stoichiometry: 1.0
species: 449296

518568
type: SpeciesReference
stoichiometry: 1.0
species: 457464

457464
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Glutamine_C5H10N2O3

518652
type: SpeciesReference
stoichiometry: 1.0
species: 458794

518616
type: SpeciesReference
stoichiometry: 1.0
species: 464518

518628
type: SpeciesReference
stoichiometry: 1.0
species: 457525

518580
type: SpeciesReference
stoichiometry: 1.0
species: 449983

458637
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Hydrogen peroxide_H2O2

993903
type: Reaction
product: 532828
product: 532816
name: _5-formethyltetrahydrofolate cyclo-ligase
is: ENSBTAG00000017102.4
is: http://identifiers.org/ec-code/6.3.3.2
fast: false
notes: R_FTHFCL subsystem: Folate Metabolism R_FTHFCL equation: [c] : 5fthf + atp --> adp + methf + pi
product: 532840
reactant: 532792
is: ENSBTAG00000020023.3
reactant: 532804
reversible: false

532828
type: SpeciesReference
stoichiometry: 1.0
species: 463855

532816
type: SpeciesReference
stoichiometry: 1.0
species: 466736

532840
type: SpeciesReference
stoichiometry: 1.0
species: 448462

532792
type: SpeciesReference
stoichiometry: 1.0
species: 449983

532804
type: SpeciesReference
stoichiometry: 1.0
species: 446166

446166
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-Formyltetrahydrofolate_C20H21N7O7

996905
type: Reaction
is: ENSBTAG00000035124.2
is: ENSBTAG00000008117.4
is: ENSBTAG00000023007.2
is: ENSBTAG00000012851.2
reactant: 562205
is: ENSBTAG00000003700.4
is: ENSBTAG00000010096.3
product: 562241
fast: false
reactant: 562217
product: 562253
notes: R_GLCt4 subsystem: Transport, Extracellular R_GLCt4 equation: glc-D[e] + na1[e] <==> glc-D[c] + na1[c] R_GLCt2r subsystem: Transport, Extracellular R_GLCt2r equation: glc-D[e] + h[e] <==> glc-D[c] + h[c]
reactant: 562229
reversible: true
product: 562265
is: ENSBTAG00000033940.2

562205
type: SpeciesReference
stoichiometry: 1.0
species: 458806

562241
type: SpeciesReference
stoichiometry: 1.0
species: 464458

562217
type: SpeciesReference
stoichiometry: 1.0
species: 464470

562253
type: SpeciesReference
stoichiometry: 2.0
species: 457356

457356
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Glucose_C6H12O6

562229
type: SpeciesReference
stoichiometry: 2.0
species: 457368

457368
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: D-Glucose_C6H12O6

562265
type: SpeciesReference
stoichiometry: 1.0
species: 458794

453602
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dGTP_C10H12N5O13P3

465343
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Superoxide anion_O2

463407
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: monoacylglycerol 2 (homo sapiens)_C3H7O2FULLR2CO2

460010
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: heparan sulfate, precursor 9_C87H129N5O69X

445757
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _4-Methyl-2-oxopentanoate_C6H9O3

462042
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 6_C69H111N6O51SX

454086
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: dITP_C10H11N4O13P3

446889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Cystine_C6H12N2O4S2

993049
type: Reaction
reactant: 525562
product: 525634
is: http://identifiers.org/ec-code/2.1.1.6
reactant: 525574
product: 525622
reactant: 525586
is: ENSBTAG00000012030.3
product: 525646
product: 525598
notes: R_34DHPHAMT subsystem: Tyrosine metabolism R_34DHPHAMT equation: [c] : 34dhpha + amet --> ahcys + h + homoval R_DOPAMT subsystem: Tyrosine metabolism R_DOPAMT equation: [c] : amet + dopa --> 3moxtyr + ahcys + h R_SALMCOM subsystem: Tyrosine metabolism R_SALMCOM equation: [c] : amet + nrpphr --> ahcys + h + normete-L
fast: false
product: 525610
reactant: 525550
reversible: false

525562
type: SpeciesReference
stoichiometry: 3.0
species: 449236

525634
type: SpeciesReference
stoichiometry: 1.0
species: 445227

445227
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Methoxytyramine_C9H14NO2

525574
type: SpeciesReference
stoichiometry: 1.0
species: 444683

444683
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3,4-Dihydroxyphenylacetate_C8H7O4

525622
type: SpeciesReference
stoichiometry: 1.0
species: 465063

465063
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Normetanephrine_C9H14NO3

525586
type: SpeciesReference
stoichiometry: 1.0
species: 454523

525646
type: SpeciesReference
stoichiometry: 3.0
species: 458794

525598
type: SpeciesReference
stoichiometry: 3.0
species: 448813

525610
type: SpeciesReference
stoichiometry: 1.0
species: 459433

459433
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Homovanillate_C9H9O4

525550
type: SpeciesReference
stoichiometry: 1.0
species: 465087

459481
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: heptadecanoyl carnitine_C24H47NO4

457912
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Glycolate_C2H3O3

471879
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: zymosterol_C27H44O

456871
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: galactosyl glucosyl ceramide_C30H56NO12FULLRCO

456379
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: glucosyl-(alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C64H107N2O50X

989210
type: Reaction
reactant: 490132
reversible: false
product: 490180
product: 490144
is: http://identifiers.org/ec-code/6.3.4.2
reactant: 490120
name: CTP synthase (glutamine)
notes: R_CTPS2 subsystem: Pyrimidine Biosynthesis R_CTPS2 equation: [c] : atp + gln-L + h2o + utp --> adp + ctp + glu-L + (2) h + pi
reactant: 490096
reactant: 490108
product: 490168
product: 490192
product: 490156
fast: false
is: ENSBTAG00000017017.3

490132
type: SpeciesReference
stoichiometry: 1.0
species: 471179

490180
type: SpeciesReference
stoichiometry: 2.0
species: 458794

490144
type: SpeciesReference
stoichiometry: 1.0
species: 466736

490120
type: SpeciesReference
stoichiometry: 1.0
species: 458685

490096
type: SpeciesReference
stoichiometry: 1.0
species: 457464

490108
type: SpeciesReference
stoichiometry: 1.0
species: 449983

490168
type: SpeciesReference
stoichiometry: 1.0
species: 448462

490192
type: SpeciesReference
stoichiometry: 1.0
species: 452697

452697
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: CTP_C9H12N3O14P3

490156
type: SpeciesReference
stoichiometry: 1.0
species: 457525

471661
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane_C27H48O4

464906
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Nicotinate D-ribonucleoside_C11H13NO6

470567
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Thromboxane A2_C20H31O5

993061
type: Reaction
reactant: 525658
product: 525682
product: 525694
reversible: true
is: http://identifiers.org/ec-code/2.7.3.2
reactant: 525670
name: ATP Creatine kinase
notes: R_CK subsystem: Urea cycle/amino group metabolism R_CK equation: [m] : atp + creat <==> adp + pcreat
is: ENSBTAG00000001003.2
fast: false

525658
type: SpeciesReference
stoichiometry: 1.0
species: 451816

451816
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Creatine_C4H9N3O2

525682
type: SpeciesReference
stoichiometry: 1.0
species: 448486

525694
type: SpeciesReference
stoichiometry: 1.0
species: 466334

466334
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Phosphocreatine_C4H9N3O5P

525670
type: SpeciesReference
stoichiometry: 1.0
species: 450007

459781
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: heparan sulfate, degradation product 6_C67H98N4O83S9

469552
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: tetracosapentaenoyl coenzyme A, n-3_C45H68N7O17P3S

444575
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _2-Oxoadipate_C6H6O5

451708
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Core 3_C16H27N2O10X

988262
type: Reaction
product: 480956
fast: false
is: http://identifiers.org/ec-code/3.1.1.3
reversible: false
product: 480944
product: 480980
product: 480968
reactant: 480932
reactant: 480908
notes: R_LPS2 subsystem: Triacylglycerol Synthesis R_LPS2 equation: [c] : dag_hs + h2o --> Rtotal + h + mag_hs R_LPS subsystem: Triacylglycerol Synthesis R_LPS equation: [c] : h2o + tag_hs --> Rtotal3 + dag_hs + h
product: 480992
is: ENSBTAG00000012855.4
reactant: 480920

480956
type: SpeciesReference
stoichiometry: 1.0
species: 452951

480944
type: SpeciesReference
stoichiometry: 1.0
species: 463395

480980
type: SpeciesReference
stoichiometry: 1.0
species: 447129

480968
type: SpeciesReference
stoichiometry: 1.0
species: 447202

447202
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: R total_CO2FULLR

480932
type: SpeciesReference
stoichiometry: 2.0
species: 458685

480908
type: SpeciesReference
stoichiometry: 1.0
species: 452951

480992
type: SpeciesReference
stoichiometry: 2.0
species: 458794

480920
type: SpeciesReference
stoichiometry: 1.0
species: 469298

989891
type: Reaction
product: 495839
notes: R_AGMTm subsystem: Arginine and Proline Metabolism R_AGMTm equation: [m] : agm + h2o --> ptrc + urea
reactant: 495827
reactant: 495815
name: agmatinase (m)
is: ENSBTAG00000002478.4
product: 495851
is: http://identifiers.org/ec-code/3.5.3.11
fast: false
reversible: false

495839
type: SpeciesReference
stoichiometry: 1.0
species: 467801

495827
type: SpeciesReference
stoichiometry: 1.0
species: 448753

448753
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Agmatine_C5H16N4

495815
type: SpeciesReference
stoichiometry: 1.0
species: 458733

495851
type: SpeciesReference
stoichiometry: 1.0
species: 471107

471107
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Urea_CH4N2O

996253
type: Reaction
is: ENSBTAG00000003700.4
reactant: 557297
product: 557333
is: ENSBTAG00000035124.2
product: 557357
is: ENSBTAG00000033940.2
notes: R_H2Ot subsystem: Transport, Extracellular R_H2Ot equation: h2o[e] <==> h2o[c] R_UREAt5 subsystem: Transport, Extracellular R_UREAt5 equation: h2o[e] + urea[e] <==> h2o[c] + urea[c] R_GLCt4_2 subsystem: Transport, Extracellular R_GLCt4_2 equation: glc-D[e] + (2) na1[e] <==> glc-D[c] + (2) na1[c] R_GLCt2_2 subsystem: Transport, Extracellular R_GLCt2_2 equation: glc-D[e] + (2) h[e] <==> glc-D[c] + (2) h[c] R_UREAt subsystem: Transport, Extracellular R_UREAt equation: urea[e] <==> urea[c] R_GALt2_2 subsystem: Transport, Extracellular R_GALt2_2 equation: gal[e] + (2) h[e] <==> gal[c] + (2) h[c] R_GALt4_2 subsystem: Transport, Extracellular R_GALt4_2 equation: gal[e] + (2) na1[e] <==> gal[c] + (2) na1[c] R_NAt subsystem: Transport, Extracellular R_NAt equation: na1[e] <==> na1[c]
is: ENSBTAG00000008117.4
reversible: true
product: 557321
reactant: 557261
is: ENSBTAG00000023007.2
fast: false
product: 557370
is: ENSBTAG00000012851.2
reactant: 557285
reactant: 557273
product: 557345
reactant: 557249
reactant: 557237
product: 557309

557297
type: SpeciesReference
stoichiometry: 2.0
species: 471095

471095
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Urea_CH4N2O

557333
type: SpeciesReference
stoichiometry: 2.0
species: 458685

557357
type: SpeciesReference
stoichiometry: 4.0
species: 458794

557321
type: SpeciesReference
stoichiometry: 5.0
species: 464458

557261
type: SpeciesReference
stoichiometry: 5.0
species: 464470

557370
type: SpeciesReference
stoichiometry: 2.0
species: 471083

557285
type: SpeciesReference
stoichiometry: 2.0
species: 458697

458697
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: H2O_H2O

557273
type: SpeciesReference
stoichiometry: 2.0
species: 457368

557345
type: SpeciesReference
stoichiometry: 2.0
species: 457356

557249
type: SpeciesReference
stoichiometry: 4.0
species: 458806

557237
type: SpeciesReference
stoichiometry: 2.0
species: 456677

456677
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: D-Galactose_C6H12O6

557309
type: SpeciesReference
stoichiometry: 2.0
species: 456665

456665
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Galactose_C6H12O6

466531
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: phosphatidylglycerol (homo sapiens)_C6H12O6PFULLRCO2FULLR2CO2

445830
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-Nitrophenyl sulfate_C6H4NO6S

453252
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dCTP_C9H12N3O13P3

468127
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: cis-11-retinol_C20H30O

454427
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Dolichyl phosphate D-mannose, human liver homolog_C1140H1868O90P10

447725
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Acetyl-CoA_C23H34N7O17P3S

446901
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Formylkynurenine_C11H12N2O4

463903
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: mannosyl-glucosaminyl-acylphosphatidylinositiol (H2)_C37H68NO19PFULLRCO2FULLR2CO2

995568
type: Reaction
reactant: 550103
notes: R_SIAT9g subsystem: Sphingolipid Metabolism R_SIAT9g equation: [g] : cmpacna + galgluside_hs --> cmp + gm3_hs + h
is: ENSBTAG00000011601.4
fast: false
product: 550139
reactant: 550115
product: 550127
name: Lactosylceramide alpha-2,3-sialyltransferase, Golgi apparatus
product: 550151
is: http://identifiers.org/ec-code/2.4.99.9
reversible: false

550103
type: SpeciesReference
stoichiometry: 1.0
species: 451471

550139
type: SpeciesReference
stoichiometry: 1.0
species: 451422

550115
type: SpeciesReference
stoichiometry: 1.0
species: 456883

456883
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: galactosyl glucosyl ceramide_C30H56NO12FULLRCO

550127
type: SpeciesReference
stoichiometry: 1.0
species: 458819

550151
type: SpeciesReference
stoichiometry: 1.0
species: 458058

458058
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: ganglioside GM3 (homo sapiens)_C41H72N2O20FULLRCO

468659
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: L-Serine_C3H7NO3

990804
type: Reaction
fast: false
name: asparagine synthase (glutamine-hydrolysing)
product: 503122
reactant: 503086
product: 503110
product: 503146
reactant: 503061
reactant: 503073
notes: R_ASNS1 subsystem: Alanine and Aspartate Metabolism R_ASNS1 equation: [c] : asp-L + atp + gln-L + h2o --> amp + asn-L + glu-L + h + ppi
reversible: false
is: ENSBTAG00000003222.3
is: http://identifiers.org/ec-code/6.3.5.4
product: 503134
product: 503098
reactant: 503049

503122
type: SpeciesReference
stoichiometry: 1.0
species: 449296

503086
type: SpeciesReference
stoichiometry: 1.0
species: 458685

503110
type: SpeciesReference
stoichiometry: 1.0
species: 449874

449874
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Asparagine_C4H8N2O3

503146
type: SpeciesReference
stoichiometry: 1.0
species: 467000

503061
type: SpeciesReference
stoichiometry: 1.0
species: 449983

503073
type: SpeciesReference
stoichiometry: 1.0
species: 449947

503134
type: SpeciesReference
stoichiometry: 1.0
species: 458794

503098
type: SpeciesReference
stoichiometry: 1.0
species: 457525

503049
type: SpeciesReference
stoichiometry: 1.0
species: 457464

460315
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Isoleucine_C6H13NO2

994167
type: Reaction
is: http://identifiers.org/ec-code/1.5.1.5
reactant: 535685
product: 535757
product: 535793
product: 535781
reactant: 535697
is: http://identifiers.org/ec-code/6.3.4.3
is: http://identifiers.org/ec-code/3.5.4.9
reactant: 535721
notes: R_MTHFDm subsystem: Folate Metabolism R_MTHFDm equation: [m] : mlthf + nadp <==> methf + nadph R_FTHFLm subsystem: Folate Metabolism R_FTHFLm equation: [m] : atp + for + thf <==> 10fthf + adp + pi R_MTHFCm subsystem: Folate Metabolism R_MTHFCm equation: [m] : h2o + methf <==> 10fthf + h
reactant: 535709
product: 535817
reactant: 535673
reactant: 535733
product: 535805
reversible: true
product: 535769
reactant: 535745
fast: false
is: ENSBTAG00000009846.4

535685
type: SpeciesReference
stoichiometry: 1.0
species: 458733

535757
type: SpeciesReference
stoichiometry: 1.0
species: 463867

463867
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _5,10-Methenyltetrahydrofolate_C20H20N7O6

535793
type: SpeciesReference
stoichiometry: 2.0
species: 443887

443887
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _10-Formyltetrahydrofolate_C20H21N7O7

535781
type: SpeciesReference
stoichiometry: 1.0
species: 448486

535697
type: SpeciesReference
stoichiometry: 1.0
species: 455883

455883
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Formate_CH1O2

535721
type: SpeciesReference
stoichiometry: 1.0
species: 469915

469915
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _5,6,7,8-Tetrahydrofolate_C19H21N7O6

535709
type: SpeciesReference
stoichiometry: 1.0
species: 450007

535817
type: SpeciesReference
stoichiometry: 1.0
species: 458843

535673
type: SpeciesReference
stoichiometry: 1.0
species: 463867

535733
type: SpeciesReference
stoichiometry: 1.0
species: 464157

464157
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _5,10-Methylenetetrahydrofolate_C20H21N7O6

535805
type: SpeciesReference
stoichiometry: 1.0
species: 464723

535769
type: SpeciesReference
stoichiometry: 1.0
species: 466784

535745
type: SpeciesReference
stoichiometry: 1.0
species: 464663

990420
type: Reaction
reactant: 500229
reversible: false
notes: R_DOLPGT2_Ler subsystem: N-Glycan Biosynthesis R_DOLPGT2_Ler equation: [r] : (0.1) dolglcp_L + (0.1) g1m8mpdol_L --> (0.1) dolp_L + (0.1) g2m8mpdol_L + h R_DOLPGT2_Uer subsystem: N-Glycan Biosynthesis R_DOLPGT2_Uer equation: [r] : (0.1) dolglcp_U + (0.1) g1m8mpdol_U --> (0.1) dolp_U + (0.1) g2m8mpdol_U + h
fast: false
reactant: 500217
is: ENSBTAG00000018192.3
product: 500265
product: 500301
reactant: 500253
product: 500277
product: 500313
reactant: 500241
product: 500289

500229
type: SpeciesReference
stoichiometry: 1.0
species: 454415

454415
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Dolichyl beta-D-glucosyl phosphate, human uterine homolog_C1085H1780O90P10

500217
type: SpeciesReference
stoichiometry: 1.0
species: 454391

454391
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Dolichyl beta-D-glucosyl phosphate, human liver homolog_C1140H1868O90P10

500265
type: SpeciesReference
stoichiometry: 1.0
species: 454487

454487
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Dolichol phosphate, human liver homolog_C1080H1758O40P10

500301
type: SpeciesReference
stoichiometry: 1.0
species: 454511

454511
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Dolichol phosphate, human uterine homolog_C1025H1670O40P10

500253
type: SpeciesReference
stoichiometry: 1.0
species: 456427

456427
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: alpha-D-Glucosyl-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1840H3028N20O670P20

500277
type: SpeciesReference
stoichiometry: 1.0
species: 456488

456488
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: (alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1845H3040N20O720P20

500313
type: SpeciesReference
stoichiometry: 2.0
species: 458867

500241
type: SpeciesReference
stoichiometry: 1.0
species: 456439

456439
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: alpha-D-Glucosyl-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1785H2940N20O670P20

500289
type: SpeciesReference
stoichiometry: 1.0
species: 456475

465718
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: naphthalene epoxide_C10H8O

459553
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: heparan sulfate, degradation product 12_C55H82N3O64S6

988862
type: Reaction
reactant: 486646
is: ENSBTAG00000014847.4
reactant: 486658
product: 486695
fast: false
notes: R_BBHOX subsystem: Lysine Metabolism R_BBHOX equation: [c] : 4tmeabutn + akg + o2 --> co2 + crn + succ
name: _4-Trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)
product: 486671
product: 486683
reactant: 486634
reversible: false

486646
type: SpeciesReference
stoichiometry: 1.0
species: 445914

445914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-Trimethylammoniobutanoate_C7H15NO2

486658
type: SpeciesReference
stoichiometry: 1.0
species: 465234

486695
type: SpeciesReference
stoichiometry: 1.0
species: 451519

486671
type: SpeciesReference
stoichiometry: 1.0
species: 469166

469166
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Succinate_C4H4O4

486683
type: SpeciesReference
stoichiometry: 1.0
species: 451888

486634
type: SpeciesReference
stoichiometry: 1.0
species: 448946

992077
type: Reaction
product: 516970
fast: false
reactant: 516897
reactant: 516885
is: ENSBTAG00000005165.4
is: http://identifiers.org/ec-code/2.4.1.175
reversible: false
reactant: 516909
product: 517031
product: 516994
product: 516982
reactant: 516933
notes: R_GALNACT1g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT1g equation: [g] : cs,hs_linkage + udpacgal --> cs_pre + h + udp R_GALNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT5g equation: [g] : cs_e_pre3 + uacgam --> cs_e_pre4 + h + udp R_GALNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT4g equation: [g] : cs_d_pre3 + uacgam --> cs_d_pre4 + h + udp R_GALNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT3g equation: [g] : cs_c_pre2 + uacgam --> cs_c_pre3 + h + udp R_GALNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT2g equation: [g] : cs_a,b_pre2 + uacgam --> cs_a,b_pre3 + h + udp
reactant: 516873
product: 516957
reactant: 516945
reactant: 516921
is: http://identifiers.org/ec-code/2.4.1.174
product: 517018
product: 517006
is: ENSBTAG00000004613.4

516970
type: SpeciesReference
stoichiometry: 5.0
species: 470688

516897
type: SpeciesReference
stoichiometry: 4.0
species: 470652

516885
type: SpeciesReference
stoichiometry: 1.0
species: 452287

452287
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate C (GalNAc6S-GlcA), precursor 2_C37H54NO37S2X

516909
type: SpeciesReference
stoichiometry: 1.0
species: 452551

452551
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 3_C37H52NO43S4X

517031
type: SpeciesReference
stoichiometry: 1.0
species: 452599

452599
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate precursor (GalNAc-GlcA-(Gal)2-Xyl-L-Ser (protein))_C31H49NO25X

516994
type: SpeciesReference
stoichiometry: 1.0
species: 452299

452299
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate C (GalNAc6S-GlcA), precursor 3_C45H67N2O42S2X

516982
type: SpeciesReference
stoichiometry: 5.0
species: 458819

516933
type: SpeciesReference
stoichiometry: 1.0
species: 452009

516873
type: SpeciesReference
stoichiometry: 1.0
species: 452407

516957
type: SpeciesReference
stoichiometry: 1.0
species: 452419

452419
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 4_C45H66N2O45S3X

516945
type: SpeciesReference
stoichiometry: 1.0
species: 452033

452033
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate A (GalNAc4S-GlcA) and B (IdoA2S-GalNAc4S), precursor 2_C37H54NO37S2X

516921
type: SpeciesReference
stoichiometry: 1.0
species: 470763

470763
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646

517018
type: SpeciesReference
stoichiometry: 1.0
species: 452563

452563
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 4_C45H65N2O48S4X

517006
type: SpeciesReference
stoichiometry: 1.0
species: 452046

452046
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate A (GalNAc4S-GlcA) and B (IdoA2S-GalNAc4S), precursor 3_C45H67N2O42S2X

997068
type: Reaction
reactant: 564422
fast: false
product: 564482
is: ENSBTAG00000025669.3
reactant: 564434
reactant: 564398
product: 564506
product: 564494
product: 564458
product: 564446
reactant: 564410
notes: R_B3GALT42g subsystem: Sphingolipid Metabolism R_B3GALT42g equation: [g] : gm2_hs + udpgal --> gm1_hs + h + udp R_B3GALT41g subsystem: Sphingolipid Metabolism R_B3GALT41g equation: [g] : ga2_hs + udpgal --> ga1_hs + h + udp R_B3GALT43g subsystem: Sphingolipid Metabolism R_B3GALT43g equation: [g] : gd2_hs + udpgal --> gd1b_hs + h + udp R_B3GALT44g subsystem: Sphingolipid Metabolism R_B3GALT44g equation: [g] : gt2_hs + udpgal --> gt1c_hs + h + udp
is: http://identifiers.org/ec-code/2.4.1.62
reactant: 564386
reversible: false
product: 564470

564422
type: SpeciesReference
stoichiometry: 1.0
species: 458033

458033
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: ganglioside GM2 (homo sapiens)_C49H85N3O25FULLRCO

564482
type: SpeciesReference
stoichiometry: 1.0
species: 456592

456592
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GA1 (homo sapiens)_C44H79N2O22FULLRCO

564434
type: SpeciesReference
stoichiometry: 4.0
species: 470848

564398
type: SpeciesReference
stoichiometry: 1.0
species: 456605

456605
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GA2 (homo sapiens)_C38H69N2O17FULLRCO

564506
type: SpeciesReference
stoichiometry: 1.0
species: 457127

457127
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GD1b (homo sapiens)_C66H111N4O38FULLRCO

564494
type: SpeciesReference
stoichiometry: 1.0
species: 458372

458372
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GT1c (homo sapiens)_C77H127N5O46FULLRCO

564458
type: SpeciesReference
stoichiometry: 4.0
species: 470688

564446
type: SpeciesReference
stoichiometry: 1.0
species: 457997

564410
type: SpeciesReference
stoichiometry: 1.0
species: 458384

458384
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GT2 (homo sapiens)_C71H117N5O41FULLRCO

564386
type: SpeciesReference
stoichiometry: 1.0
species: 457151

564470
type: SpeciesReference
stoichiometry: 4.0
species: 458819

468346
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: de-Fuc, reducing GlcNAc removed form of PA6 (w/o peptide linkage)_C76H123N5O57

469951
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Thiamin monophosphate_C12H16N4O4PS

995580
type: Reaction
product: 550224
reactant: 550187
product: 550236
name: cytochrome p450 4F12/4F2
is: ENSBTAG00000016375.3
reversible: false
notes: R_P4504F122r subsystem: Eicosanoid Metabolism R_P4504F122r equation: [r] : h + leuktrB4 + nadph + o2 --> h2o + leuktrB4woh + nadp
reactant: 550175
reactant: 550199
fast: false
product: 550212
reactant: 550163

550224
type: SpeciesReference
stoichiometry: 1.0
species: 458758

550187
type: SpeciesReference
stoichiometry: 1.0
species: 462393

462393
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Leukotriene B4_C20H31O4

550236
type: SpeciesReference
stoichiometry: 1.0
species: 464687

550175
type: SpeciesReference
stoichiometry: 1.0
species: 464747

550199
type: SpeciesReference
stoichiometry: 1.0
species: 458867

550212
type: SpeciesReference
stoichiometry: 1.0
species: 462405

462405
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: w-hydroxyl leukotriene B4_C20H31O5

550163
type: SpeciesReference
stoichiometry: 1.0
species: 465282

993361
type: Reaction
is: http://identifiers.org/ec-code/2.7.2.3
reactant: 527702
product: 527714
reversible: true
reactant: 527690
is: ENSBTAG00000018824.4
notes: R_PGK subsystem: Glycolysis/Gluconeogenesis R_PGK equation: [c] : 3pg + atp <==> 13dpg + adp
fast: false
is: ENSBTAG00000019762.4
name: phosphoglycerate kinase
product: 527726
is: ENSBTAG00000000894.4

527702
type: SpeciesReference
stoichiometry: 1.0
species: 445323

527714
type: SpeciesReference
stoichiometry: 1.0
species: 448462

527690
type: SpeciesReference
stoichiometry: 1.0
species: 449983

527726
type: SpeciesReference
stoichiometry: 1.0
species: 444057

444057
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Phospho-D-glyceroyl phosphate_C3H4O10P2

448633
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: adrenic acid_C22H35O2

459974
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: heparan sulfate, precursor 6_C65H96N3O53X

466916
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: (R)-Pantothenate_C9H16NO5

451072
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Choline phosphate_C5H13NO4P

993879
type: Reaction
product: 532443
modifier: 532651
product: 532613
reactant: 532418
reactant: 532309
reactant: 532296
product: 532479
reactant: 532382
reactant: 532272
product: 532455
product: 532600
reversible: false
product: 532467
reactant: 532370
reactant: 532358
product: 532492
reactant: 532334
reactant: 532322
product: 532540
is: ENSBTAG00000030335.2
product: 532552
product: 532516
is: http://identifiers.org/ec-code/1.2.1.3
product: 532528
product: 532504
reactant: 532406
modifier: 532626
is: http://identifiers.org/ec-code/1.2.1.21
reactant: 532260
notes: R_4HGLSDm subsystem: Arginine and Proline Metabolism R_4HGLSDm equation: [m] : 4hglusa + h2o + nad <==> e4hglu + (2) h + nadh R_LCADim subsystem: Pyruvate Metabolism R_LCADim equation: [m] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDDm subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDDm equation: [m] : gcald + h2o + nad --> glyclt + (2) h + nadh R_P5CDm subsystem: Glutamate metabolism R_P5CDm equation: [m] : 1pyr5c + (2) h2o + nad --> glu-L + h + nadh R_BAMPPALDOXm subsystem: beta-Alanine metabolism R_BAMPPALDOXm equation: [m] : bamppald + h2o + nad --> ala-B + (2) h + nadh R_NABTNOm subsystem: Arginine and Proline Metabolism R_NABTNOm equation: [m] : h2o + n4abutn + nad --> 4aabutn + (2) h + nadh R_HPROxm subsystem: Arginine and Proline Metabolism R_HPROxm equation: [m] : 4hpro-LT + nad --> 1p3h5c + (2) h + nadh R_PYLALDOXm subsystem: Limonene and pinene degradation R_PYLALDOXm equation: [m] : h2o + nad + pylald --> (2) h + nadh + peracd R_LCADi_Dm subsystem: Pyruvate Metabolism R_LCADi_Dm equation: [m] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_IMACTD_m subsystem: Histidine Metabolism R_IMACTD_m equation: [m] : h2o + im4act + nad --> (2) h + im4ac + nadh R_ALDD20xm subsystem: Tryptophan metabolism R_ALDD20xm equation: [m] : h2o + id3acald + nad --> (2) h + ind3ac + nadh R_PHCDm subsystem: Arginine and Proline Metabolism R_PHCDm equation: [m] : 1p3h5c + (2) h2o + nad --> e4hglu + h + nadh R_5HOXINDACTOXm subsystem: Tryptophan metabolism R_5HOXINDACTOXm equation: [m] : 5hoxindact + h2o + nad --> 5hoxindoa + (2) h + nadh R_GLACOm subsystem: Ascorbate and Aldarate Metabolism R_GLACOm equation: [m] : glac + (2) h2o + nad --> glcr + (3) h + nadh
modifier: 532663
fast: false
reactant: 532346
is: http://identifiers.org/ec-code/1.5.1.12
modifier: 532689
reactant: 532394
product: 532564
reactant: 532284
modifier: 532676
modifier: 532639
product: 532576
reactant: 532431
product: 532588

532443
type: SpeciesReference
stoichiometry: 1.0
species: 444213

444213
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-1-Pyrroline-3-hydroxy-5-carboxylate_C5H6NO3

454956
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-erythro-4-Hydroxyglutamate_C5H8NO5

532613
type: SpeciesReference
stoichiometry: 13.0
species: 464602

532418
type: SpeciesReference
stoichiometry: 13.0
species: 464542

532309
type: SpeciesReference
stoichiometry: 1.0
species: 446226

446226
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _5-Hydroxyindoleacetaldehyde_C10H9NO2

532296
type: SpeciesReference
stoichiometry: 1.0
species: 464434

464434
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: N4-Acetylaminobutanal_C6H11NO2

532479
type: SpeciesReference
stoichiometry: 1.0
species: 446250

532382
type: SpeciesReference
stoichiometry: 1.0
species: 467897

532272
type: SpeciesReference
stoichiometry: 1.0
species: 444213

532455
type: SpeciesReference
stoichiometry: 1.0
species: 445516

532600
type: SpeciesReference
stoichiometry: 1.0
species: 457428

457428
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: D-Glucarate_C6H8O8

532467
type: SpeciesReference
stoichiometry: 1.0
species: 457900

457900
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Glycolate_C2H3O3

532370
type: SpeciesReference
stoichiometry: 1.0
species: 457344

457344
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: D-glucurono-6,3-lactone_C6H8O6

532358
type: SpeciesReference
stoichiometry: 1.0
species: 462222

532492
type: SpeciesReference
stoichiometry: 1.0
species: 454956

532334
type: SpeciesReference
stoichiometry: 1.0
species: 460206

460206
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Indole-3-acetaldehyde_C10H9NO

532322
type: SpeciesReference
stoichiometry: 1.0
species: 460364

460364
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Imidazole-4-acetaldehyde_C5H6N2O

532540
type: SpeciesReference
stoichiometry: 1.0
species: 466507

466507
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Perillic acid_C10H13O2

532552
type: SpeciesReference
stoichiometry: 1.0
species: 449031

449031
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: beta-Alanine_C3H7NO2

532516
type: SpeciesReference
stoichiometry: 1.0
species: 457562

457562
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Glutamate_C5H8NO4

532528
type: SpeciesReference
stoichiometry: 1.0
species: 460413

460413
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Indole-3-acetate_C10H8NO2

532504
type: SpeciesReference
stoichiometry: 1.0
species: 462162

462162
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: D-Lactate_C3H5O3

532406
type: SpeciesReference
stoichiometry: 1.0
species: 462246

462246
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Lactaldehyde_C3H6O2

532260
type: SpeciesReference
stoichiometry: 1.0
species: 450092

450092
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: beta-Aminopropion aldehyde_C3H8NO

532346
type: SpeciesReference
stoichiometry: 1.0
species: 445697

445697
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: trans-4-Hydroxy-L-proline_C5H9NO3

532394
type: SpeciesReference
stoichiometry: 1.0
species: 444237

444237
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _1-Pyrroline-5-carboxylate_C5H6NO2

532564
type: SpeciesReference
stoichiometry: 1.0
species: 460339

460339
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Imidazole-4-acetate_C5H5N2O2

532284
type: SpeciesReference
stoichiometry: 15.0
species: 458733

532576
type: SpeciesReference
stoichiometry: 1.0
species: 462198

462198
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Lactate_C3H5O3

532431
type: SpeciesReference
stoichiometry: 1.0
species: 457043

457043
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Glycolaldehyde_C2H4O2

532588
type: SpeciesReference
stoichiometry: 25.0
species: 458843

991080
type: Reaction
reactant: 506108
product: 506252
reactant: 506096
product: 506192
product: 506204
is: ENSBTAG00000009583.4
product: 506180
reactant: 506144
reactant: 506072
fast: false
product: 506240
reactant: 506084
reversible: true
reactant: 506120
notes: R_CHOLtu subsystem: Transport, Extracellular R_CHOLtu equation: chol[e] <==> chol[c] R_PROSTGF2t subsystem: Transport, Extracellular R_PROSTGF2t equation: prostgf2[e] <==> prostgf2[c] R_NRPPHRtu subsystem: Transport, Extracellular R_NRPPHRtu equation: nrpphr[e] <==> nrpphr[c] R_DEBRISOQUINEt subsystem: Transport, Extracellular R_DEBRISOQUINEt equation: debrisoquine[e] <==> debrisoquine[c] R_SRTNtu subsystem: Transport, Extracellular R_SRTNtu equation: srtn[e] <==> srtn[c] R_PROSTGE2t2 subsystem: Transport, Extracellular R_PROSTGE2t2 equation: prostge2[e] <==> prostge2[c] R_DOPAtu subsystem: Transport, Extracellular R_DOPAtu equation: dopa[e] <==> dopa[c] R_HISTAtu subsystem: Transport, Extracellular R_HISTAtu equation: hista[e] <==> hista[c]
product: 506228
product: 506168
reactant: 506132
product: 506216
reactant: 506156

506108
type: SpeciesReference
stoichiometry: 1.0
species: 459325

459325
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Histamine_C5H10N3

506252
type: SpeciesReference
stoichiometry: 1.0
species: 454523

506096
type: SpeciesReference
stoichiometry: 1.0
species: 468996

468996
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Serotonin_C10H13N2O

506192
type: SpeciesReference
stoichiometry: 1.0
species: 453408

453408
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: debrisoquine_C10H14N3

506204
type: SpeciesReference
stoichiometry: 1.0
species: 450878

506180
type: SpeciesReference
stoichiometry: 1.0
species: 467546

467546
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Prostaglandin E2_C20H31O5

506144
type: SpeciesReference
stoichiometry: 1.0
species: 450890

506072
type: SpeciesReference
stoichiometry: 1.0
species: 454535

506240
type: SpeciesReference
stoichiometry: 1.0
species: 459313

459313
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Histamine_C5H10N3

506084
type: SpeciesReference
stoichiometry: 1.0
species: 453420

453420
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: debrisoquine_C10H14N3

506120
type: SpeciesReference
stoichiometry: 1.0
species: 467558

467558
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Prostaglandin E2_C20H31O5

506228
type: SpeciesReference
stoichiometry: 1.0
species: 468984

468984
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Serotonin_C10H13N2O

506168
type: SpeciesReference
stoichiometry: 1.0
species: 465087

506132
type: SpeciesReference
stoichiometry: 1.0
species: 465099

506216
type: SpeciesReference
stoichiometry: 1.0
species: 467583

467583
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Prostaglandin F2alpha_C20H33O5

506156
type: SpeciesReference
stoichiometry: 1.0
species: 467595

467595
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Prostaglandin F2alpha_C20H33O5

992629
type: Reaction
reactant: 520907
product: 520980
fast: false
is: http://identifiers.org/ec-code/1.14.13.17
is: ENSBTAG00000005287.2
notes: R_P4507A1r subsystem: Bile Acid Biosynthesis R_P4507A1r equation: [r] : chsterol + h + nadph + o2 --> h2o + nadp + xol7a
reactant: 520944
reactant: 520932
reactant: 520920
reversible: false
product: 520956
name: cytochrome P450, family 7, subfamily A, polypeptide 1
product: 520968

520907
type: SpeciesReference
stoichiometry: 1.0
species: 465282

520980
type: SpeciesReference
stoichiometry: 1.0
species: 464687

520944
type: SpeciesReference
stoichiometry: 1.0
species: 458867

520932
type: SpeciesReference
stoichiometry: 1.0
species: 464747

520920
type: SpeciesReference
stoichiometry: 1.0
species: 451156

520956
type: SpeciesReference
stoichiometry: 1.0
species: 471492

471492
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _7 alpha-Hydroxycholesterol_C27H46O2

520968
type: SpeciesReference
stoichiometry: 1.0
species: 458758

996795
type: Reaction
product: 561544
reactant: 561531
notes: R_COAtm subsystem: Transport, Mitochondrial R_COAtm equation: coa[c] <==> coa[m]
is: ENSBTAG00000023054.3
fast: false
reversible: true
name: CoA transporter

561544
type: SpeciesReference
stoichiometry: 1.0
species: 451632

561531
type: SpeciesReference
stoichiometry: 1.0
species: 451593

990396
type: Reaction
product: 500145
is: http://identifiers.org/ec-code/6.3.5.3
product: 500073
fast: false
reactant: 500001
product: 500085
reactant: 500037
is: http://identifiers.org/ec-code/2.8.2.23
product: 500121
product: 500109
product: 500061
reactant: 500013
reactant: 500049
is: ENSBTAG00000007866.3
product: 500133
reactant: 499989
reversible: false
notes: R_S3T3g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T3g equation: [g] : hs_pre15 + paps --> h + hspg + pap R_PRFGS subsystem: IMP Biosynthesis R_PRFGS equation: [c] : atp + fgam + gln-L + h2o --> adp + fpram + glu-L + h + pi
product: 500097
reactant: 500025

500145
type: SpeciesReference
stoichiometry: 1.0
species: 458794

500073
type: SpeciesReference
stoichiometry: 1.0
species: 458819

500001
type: SpeciesReference
stoichiometry: 1.0
species: 449983

500085
type: SpeciesReference
stoichiometry: 1.0
species: 460022

460022
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: heparan sulfate proteoglycan_C79H113N5O101S12X

500037
type: SpeciesReference
stoichiometry: 1.0
species: 455763

455763
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide_C8H13N2O9P

500121
type: SpeciesReference
stoichiometry: 1.0
species: 466202

466202
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Adenosine 3',5'-bisphosphate_C10H11N5O10P2

500109
type: SpeciesReference
stoichiometry: 1.0
species: 448462

500061
type: SpeciesReference
stoichiometry: 1.0
species: 466736

500013
type: SpeciesReference
stoichiometry: 1.0
species: 459902

459902
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: heparan sulfate, precursor 15_C79H114N5O98S11X

500049
type: SpeciesReference
stoichiometry: 1.0
species: 458685

500133
type: SpeciesReference
stoichiometry: 1.0
species: 455944

455944
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine_C8H15N3O8P

499989
type: SpeciesReference
stoichiometry: 1.0
species: 457464

500097
type: SpeciesReference
stoichiometry: 1.0
species: 457525

500025
type: SpeciesReference
stoichiometry: 1.0
species: 466226

991789
type: Reaction
product: 512541
notes: R_GTPCI subsystem: Tetrahydrobiopterin R_GTPCI equation: [c] : gtp + h2o --> ahdt + for + h R_GTPCIn subsystem: Tetrahydrobiopterin R_GTPCIn equation: [n] : gtp + h2o --> ahdt + for + h
is: http://identifiers.org/ec-code/3.5.4.16
reversible: false
product: 512504
reactant: 512456
reactant: 512468
product: 512516
is: ENSBTAG00000040151.1
product: 512553
reactant: 512443
product: 512492
fast: false
reactant: 512480
product: 512529

512541
type: SpeciesReference
stoichiometry: 1.0
species: 455895

455895
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Formate_CH1O2

512504
type: SpeciesReference
stoichiometry: 1.0
species: 448873

448873
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: _2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate_C9H12N5O13P3

512456
type: SpeciesReference
stoichiometry: 1.0
species: 458685

512468
type: SpeciesReference
stoichiometry: 1.0
species: 458746

512516
type: SpeciesReference
stoichiometry: 1.0
species: 458855

512553
type: SpeciesReference
stoichiometry: 1.0
species: 458794

512443
type: SpeciesReference
stoichiometry: 1.0
species: 458504

512492
type: SpeciesReference
stoichiometry: 1.0
species: 455859

455859
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Formate_CH1O2

512480
type: SpeciesReference
stoichiometry: 1.0
species: 458540

458540
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: GTP_C10H12N5O14P3

512529
type: SpeciesReference
stoichiometry: 1.0
species: 448861

469927
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Thiamin_C12H17N4OS

462923
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Gal-Xyl-L-Ser (protein)_C11H19O9X

451961
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Cortisol_C21H30O5

994239
type: Reaction
product: 536774
reactant: 536626
is: http://identifiers.org/ec-code/1.2.1.3
product: 536798
product: 536762
product: 536822
reactant: 536687
reactant: 536662
product: 536786
reactant: 536590
product: 536846
product: 536810
product: 536883
reactant: 536614
is: ENSBTAG00000023068.3
product: 536870
notes: R_LCADim subsystem: Pyruvate Metabolism R_LCADim equation: [m] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDDm subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDDm equation: [m] : gcald + h2o + nad --> glyclt + (2) h + nadh R_BAMPPALDOXm subsystem: beta-Alanine metabolism R_BAMPPALDOXm equation: [m] : bamppald + h2o + nad --> ala-B + (2) h + nadh R_ALDD2xm subsystem: Glycolysis/Gluconeogenesis R_ALDD2xm equation: [m] : acald + h2o + nad --> ac + (2) h + nadh R_NABTNOm subsystem: Arginine and Proline Metabolism R_NABTNOm equation: [m] : h2o + n4abutn + nad --> 4aabutn + (2) h + nadh R_PYLALDOXm subsystem: Limonene and pinene degradation R_PYLALDOXm equation: [m] : h2o + nad + pylald --> (2) h + nadh + peracd R_LCADi_Dm subsystem: Pyruvate Metabolism R_LCADi_Dm equation: [m] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_IMACTD_m subsystem: Histidine Metabolism R_IMACTD_m equation: [m] : h2o + im4act + nad --> (2) h + im4ac + nadh R_ALDD20xm subsystem: Tryptophan metabolism R_ALDD20xm equation: [m] : h2o + id3acald + nad --> (2) h + ind3ac + nadh R_5HOXINDACTOXm subsystem: Tryptophan metabolism R_5HOXINDACTOXm equation: [m] : 5hoxindact + h2o + nad --> 5hoxindoa + (2) h + nadh R_GLACOm subsystem: Ascorbate and Aldarate Metabolism R_GLACOm equation: [m] : glac + (2) h2o + nad --> glcr + (3) h + nadh
is: ENSBTAG00000020385.3
product: 536834
reactant: 536638
is: ENSBTAG00000010119.4
product: 536858
reactant: 536675
reactant: 536650
is: ENSBTAG00000008743.3
reactant: 536712
reactant: 536725
reactant: 536578
fast: false
reactant: 536699
is: ENSBTAG00000036266.1
is: ENSBTAG00000014470.4
reactant: 536602
product: 536750
is: http://identifiers.org/ec-code/1.2.1.21
product: 536737
reversible: false

536774
type: SpeciesReference
stoichiometry: 1.0
species: 462162

536626
type: SpeciesReference
stoichiometry: 1.0
species: 446226

536798
type: SpeciesReference
stoichiometry: 1.0
species: 460413

536762
type: SpeciesReference
stoichiometry: 1.0
species: 446250

536822
type: SpeciesReference
stoichiometry: 1.0
species: 449031

536687
type: SpeciesReference
stoichiometry: 1.0
species: 467897

536662
type: SpeciesReference
stoichiometry: 1.0
species: 462222

536786
type: SpeciesReference
stoichiometry: 1.0
species: 447557

536590
type: SpeciesReference
stoichiometry: 12.0
species: 458733

536846
type: SpeciesReference
stoichiometry: 1.0
species: 462198

536810
type: SpeciesReference
stoichiometry: 1.0
species: 466507

536883
type: SpeciesReference
stoichiometry: 11.0
species: 464602

536614
type: SpeciesReference
stoichiometry: 1.0
species: 464434

536870
type: SpeciesReference
stoichiometry: 1.0
species: 457428

536834
type: SpeciesReference
stoichiometry: 1.0
species: 460339

536638
type: SpeciesReference
stoichiometry: 1.0
species: 460364

536858
type: SpeciesReference
stoichiometry: 23.0
species: 458843

536675
type: SpeciesReference
stoichiometry: 1.0
species: 457344

536650
type: SpeciesReference
stoichiometry: 1.0
species: 460206

536712
type: SpeciesReference
stoichiometry: 11.0
species: 464542

536725
type: SpeciesReference
stoichiometry: 1.0
species: 457043

536578
type: SpeciesReference
stoichiometry: 1.0
species: 450092

536699
type: SpeciesReference
stoichiometry: 1.0
species: 462246

536602
type: SpeciesReference
stoichiometry: 1.0
species: 447629

447629
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Acetaldehyde_C2H4O

536750
type: SpeciesReference
stoichiometry: 1.0
species: 457900

536737
type: SpeciesReference
stoichiometry: 1.0
species: 445516

462611
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: linoelaidic acid (all trans C18:2)_C18H31O2

457755
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Glycine_C2H5NO2

446238
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-Hydroxyindoleacetate_C10H8NO3

996037
type: Reaction
reactant: 555407
reversible: false
notes: R_BMTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_BMTer_L equation: [r] : (0.1) dolmanp_L + memgacpail_hs --> (0.1) dolp_L + h + m2emgacpail_hs R_BMTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_BMTer_U equation: [r] : (0.1) dolmanp_U + memgacpail_hs --> (0.1) dolp_U + h + m2emgacpail_hs R_H3MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3MTer_L equation: [r] : (0.1) dolmanp_L + m2gacpail_hs --> (0.1) dolp_L + h + m3gacpail_hs R_H3MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3MTer_U equation: [r] : (0.1) dolmanp_U + m2gacpail_hs --> (0.1) dolp_U + h + m3gacpail_hs
fast: false
product: 555443
product: 555468
reactant: 555383
reactant: 555395
is: ENSBTAG00000012740.4
product: 555480
product: 555431
product: 555455
reactant: 555419

555407
type: SpeciesReference
stoichiometry: 1.0
species: 454463

454463
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Dolichyl phosphate D-mannose, human uterine homolog_C1085H1780O90P10

555443
type: SpeciesReference
stoichiometry: 2.0
species: 463069

463069
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: trimannosyl-glucosaminyl-acylphosphatidylinositol (H4)_C49H88NO29PFULLRCO2FULLR2CO2

555468
type: SpeciesReference
stoichiometry: 2.0
species: 463007

463007
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: (dimannosyl),(phosphoethanolaminyl)-mannosyl-glucosylaminyl-acylphosphatidylinositol (H6)_C51H94N2O32P2FULLRCO2FULLR2CO2

555383
type: SpeciesReference
stoichiometry: 2.0
species: 463709

463709
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: (mannosyl),(phosphoethanolaminyl)-mannosyl-glucosylaminyl-acylphosphatidylinositol (B)_C45H84N2O27P2FULLRCO2FULLR2CO2

555395
type: SpeciesReference
stoichiometry: 2.0
species: 463019

555480
type: SpeciesReference
stoichiometry: 4.0
species: 458867

555431
type: SpeciesReference
stoichiometry: 1.0
species: 454487

555455
type: SpeciesReference
stoichiometry: 1.0
species: 454511

555419
type: SpeciesReference
stoichiometry: 1.0
species: 454439

454439
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Dolichyl phosphate D-mannose, human liver homolog_C1140H1868O90P10

444286
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _2,4 dihydroxy nitrophenol_C6H5NO4

989162
type: Reaction
reversible: false
product: 489795
reactant: 489759
product: 489783
reactant: 489771
notes: R_PSERT subsystem: Glycine, Serine, and Threonine Metabolism R_PSERT equation: [c] : 3php + glu-L --> akg + pser-L
is: ENSBTAG00000013960.4
is: http://identifiers.org/ec-code/2.6.1.52
name: phosphoserine transaminase
fast: false

489795
type: SpeciesReference
stoichiometry: 1.0
species: 467716

467716
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: O-Phospho-L-serine_C3H6NO6P

489759
type: SpeciesReference
stoichiometry: 1.0
species: 445335

445335
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Phosphohydroxypyruvate_C3H2O7P

489783
type: SpeciesReference
stoichiometry: 1.0
species: 448946

489771
type: SpeciesReference
stoichiometry: 1.0
species: 457525

466471
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Peptidyl-L-lysine_XH

992653
type: Reaction
notes: R_NAt3_1 subsystem: Transport, Extracellular R_NAt3_1 equation: h[e] + na1[c] <==> h[c] + na1[e]
is: ENSBTAG00000026075.3
reactant: 521113
fast: false
name: sodium proton antiporter (H:NA is 1:1)
product: 521125
product: 521137
is: ENSBTAG00000014911.3
is: ENSBTAG00000024075.3
reactant: 521101
reversible: true

521113
type: SpeciesReference
stoichiometry: 1.0
species: 464458

521125
type: SpeciesReference
stoichiometry: 1.0
species: 464470

521137
type: SpeciesReference
stoichiometry: 1.0
species: 458794

521101
type: SpeciesReference
stoichiometry: 1.0
species: 458806

454860
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Deoxyuridine_C9H12N2O5

460838
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 23_C124H201N8O106S5

448450
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Adenosylcobalamin_C72H100CoN18O17P

447189
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: R total 3 carnitine_CO2FULLR3C7H14NO2

987601
type: Reaction
product: 475200
product: 475176
is: ENSBTAG00000009231.3
reversible: false
is: http://identifiers.org/ec-code/5.3.3.1
notes: R_C3STDH1r subsystem: Cholesterol Metabolism R_C3STDH1r equation: [r] : 4mzym_int1 + nad --> 4mzym_int2 + co2 + h + nadh R_C4STMO2Pr subsystem: Cholesterol Metabolism R_C4STMO2Pr equation: [r] : 4mzym_int2 + nadp + o2 --> co2 + h + nadph + zym_int2 R_C4STMO2r subsystem: Cholesterol Metabolism R_C4STMO2r equation: [r] : 4mzym_int2 + nad + o2 --> co2 + h + nadh + zym_int2 R_C3STDH1Pr subsystem: Cholesterol Metabolism R_C3STDH1Pr equation: [r] : 4mzym_int1 + nadp --> 4mzym_int2 + co2 + h + nadph
reactant: 475086
product: 475213
reactant: 475099
product: 475188
product: 475151
reactant: 475138
reactant: 475125
reactant: 475112
fast: false
product: 475164

475200
type: SpeciesReference
stoichiometry: 4.0
species: 458867

475176
type: SpeciesReference
stoichiometry: 2.0
species: 471866

471866
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: zymosterol intermediate 2_C27H42O

475086
type: SpeciesReference
stoichiometry: 2.0
species: 465282

475213
type: SpeciesReference
stoichiometry: 2.0
species: 464615

475099
type: SpeciesReference
stoichiometry: 2.0
species: 445806

445806
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _4-Methylzymosterol intermediate 2_C28H44O

475188
type: SpeciesReference
stoichiometry: 2.0
species: 445806

475151
type: SpeciesReference
stoichiometry: 2.0
species: 464747

475138
type: SpeciesReference
stoichiometry: 2.0
species: 445794

445794
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _4-Methylzymosterol intermediate 1_C29H46O3

475125
type: SpeciesReference
stoichiometry: 2.0
species: 464566

475112
type: SpeciesReference
stoichiometry: 2.0
species: 464687

475164
type: SpeciesReference
stoichiometry: 4.0
species: 451557

451557
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: CO2_CO2

990696
type: Reaction
reversible: false
product: 502472
notes: R_DHDPBMTm subsystem: Ubiquinone Biosynthesis R_DHDPBMTm equation: [m] : 3dpdhb + amet --> 3dpdhb_me + ahcys + h R_COQ3m subsystem: Ubiquinone Biosynthesis R_COQ3m equation: [m] : 2dpmhobq + amet --> ahcys + h + q10
product: 502484
reactant: 502423
product: 502448
is: ENSBTAG00000019729.4
reactant: 502436
product: 502460
reactant: 502411
fast: false

502472
type: SpeciesReference
stoichiometry: 1.0
species: 444853

444853
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _3-Decaprenyl-4-hydroxy-5-methoxybenzoate_C58H87O4

502484
type: SpeciesReference
stoichiometry: 2.0
species: 458843

502423
type: SpeciesReference
stoichiometry: 1.0
species: 444841

444841
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _3-Decaprenyl-4,5-dihdydroxybenzoate_C57H85O4

502448
type: SpeciesReference
stoichiometry: 2.0
species: 448825

448825
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

502436
type: SpeciesReference
stoichiometry: 1.0
species: 444431

444431
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _2-Decaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone_C58H88O4

502460
type: SpeciesReference
stoichiometry: 1.0
species: 467970

467970
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Ubiquinone-10_C59H90O4

502411
type: SpeciesReference
stoichiometry: 2.0
species: 449248

449248
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: S-Adenosyl-L-methionine_C15H23N6O5S

445023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: _3-Hydroxypropionyl-CoA_C24H36N7O18P3S

458082
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: GMP_C10H12N5O8P

446744
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: heptaglutamyl folate (THF)_C49H57N13O24

451447
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: CMP_C9H12N3O8P

451925
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: L-Carnitine_C7H15NO3

447521
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Acetate_C2H3O2

988646
type: Reaction
product: 484581
product: 484556
product: 484569
reversible: true
notes: R_BDHm subsystem: Butanoate Metabolism R_BDHm equation: [m] : bhb + nad <==> acac + h + nadh
is: ENSBTAG00000000448.3
name: (R)-3-Hydroxybutanoate:NAD+ oxidoreductase
reactant: 484532
is: http://identifiers.org/ec-code/1.1.1.30
fast: false
reactant: 484544

484581
type: SpeciesReference
stoichiometry: 1.0
species: 464602

484556
type: SpeciesReference
stoichiometry: 1.0
species: 447593

447593
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Acetoacetate_C4H5O3

484569
type: SpeciesReference
stoichiometry: 1.0
species: 458843

484532
type: SpeciesReference
stoichiometry: 1.0
species: 450140

450140
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: (R)-3-Hydroxybutanoate_C4H7O3

484544
type: SpeciesReference
stoichiometry: 1.0
species: 464542

466190
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Adenosine 3',5'-bisphosphate_C10H11N5O10P2

995364
type: Reaction
reactant: 548537
is: http://identifiers.org/ec-code/3.6.1.1
product: 548669
is: ENSBTAG00000017077.4
product: 548609
product: 548657
reactant: 548585
reactant: 548573
product: 548645
product: 548633
notes: R_PPAer subsystem: Miscellaneous R_PPAer equation: [r] : h2o + ppi --> h + (2) pi R_G6PPer subsystem: Glycolysis/Gluconeogenesis R_G6PPer equation: [r] : g6p + h2o --> glc-D + pi R_CBPPer subsystem: Glycolysis/Gluconeogenesis R_CBPPer equation: [r] : cbp + glc-D + h --> co2 + g6p + nh4
reactant: 548549
is: ENSBTAG00000000720.4
is: ENSBTAG00000016253.3
product: 548621
fast: false
reactant: 548561
is: http://identifiers.org/ec-code/3.1.3.9
reversible: false
reactant: 548597
is: ENSBTAG00000004241.2

548537
type: SpeciesReference
stoichiometry: 1.0
species: 467036

467036
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Diphosphate_HO7P2

548669
type: SpeciesReference
stoichiometry: 1.0
species: 458867

548609
type: SpeciesReference
stoichiometry: 3.0
species: 466808

466808
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Phosphate_HO4P

548657
type: SpeciesReference
stoichiometry: 1.0
species: 457404

457404
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: D-Glucose_C6H12O6

548585
type: SpeciesReference
stoichiometry: 1.0
species: 457404

548573
type: SpeciesReference
stoichiometry: 2.0
species: 458758

548645
type: SpeciesReference
stoichiometry: 1.0
species: 464882

464882
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Ammonium_H4N

548633
type: SpeciesReference
stoichiometry: 1.0
species: 456579

456579
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: D-Glucose 6-phosphate_C6H11O9P

548549
type: SpeciesReference
stoichiometry: 1.0
species: 450720

450720
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Carbamoyl phosphate_CH2NO5P

548621
type: SpeciesReference
stoichiometry: 1.0
species: 451557

548561
type: SpeciesReference
stoichiometry: 1.0
species: 456579

548597
type: SpeciesReference
stoichiometry: 1.0
species: 458867

993145
type: Reaction
product: 526251
fast: false
product: 526239
is: ENSBTAG00000006099.4
notes: R_PI3P5K subsystem: Inositol Phosphate Metabolism R_PI3P5K equation: [c] : atp + pail3p_hs --> adp + h + pail35p_hs R_PI34P5K subsystem: Inositol Phosphate Metabolism R_PI34P5K equation: [c] : atp + pail34p_hs --> adp + h + pail345p_hs R_PIK5 subsystem: Inositol Phosphate Metabolism R_PIK5 equation: [c] : atp + pail_hs --> adp + h + pail5p_hs R_PI4P5K subsystem: Glycerophospholipid Metabolism R_PI4P5K equation: [c] : atp + pail4p_hs --> adp + h + pail45p_hs R_PI3P4K subsystem: Inositol Phosphate Metabolism R_PI3P4K equation: [c] : atp + pail3p_hs --> adp + h + pail34p_hs
is: http://identifiers.org/ec-code/2.7.1.68
reactant: 526190
reactant: 526166
product: 526275
reversible: false
reactant: 526202
product: 526227
product: 526215
product: 526263
product: 526287
reactant: 526178
reactant: 526154
is: ENSBTAG00000000710.4

526251
type: SpeciesReference
stoichiometry: 1.0
species: 466046

526239
type: SpeciesReference
stoichiometry: 1.0
species: 465998

465998
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: phosphatidylinositol-3,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

526190
type: SpeciesReference
stoichiometry: 1.0
species: 465973

465973
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: phosphatidylinositol-3,4-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

526166
type: SpeciesReference
stoichiometry: 1.0
species: 466130

466130
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: phosphatidylinositol (homo sapiens)_C9H16O9PFULLRCO2FULLR2CO2

526275
type: SpeciesReference
stoichiometry: 5.0
species: 448462

526202
type: SpeciesReference
stoichiometry: 2.0
species: 466022

466022
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1-Phosphatidyl-1D-myo-inositol 3-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

526227
type: SpeciesReference
stoichiometry: 1.0
species: 465949

526215
type: SpeciesReference
stoichiometry: 1.0
species: 466106

466106
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1-Phosphatidyl-1D-myo-inositol 5-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

526263
type: SpeciesReference
stoichiometry: 1.0
species: 465973

526287
type: SpeciesReference
stoichiometry: 5.0
species: 458794

526178
type: SpeciesReference
stoichiometry: 1.0
species: 466070

526154
type: SpeciesReference
stoichiometry: 5.0
species: 449983

991056
type: Reaction
is: ENSBTAG00000012705.3
reactant: 505927
fast: false
reactant: 505939
notes: R_DHCRD1 subsystem: Sphingolipid Metabolism R_DHCRD1 equation: [c] : dhcrm_hs + nadp --> crm_hs + h + nadph R_DHCRD2 subsystem: Sphingolipid Metabolism R_DHCRD2 equation: [c] : dhcrm_hs + fad --> crm_hs + fadh2
product: 505987
reactant: 505951
product: 505963
reversible: false
product: 505999
product: 505975

505927
type: SpeciesReference
stoichiometry: 1.0
species: 455558

455558
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

505939
type: SpeciesReference
stoichiometry: 2.0
species: 453771

453771
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dihydroceramide (homo sapiens)_C18H38NO2FULLRCO

505987
type: SpeciesReference
stoichiometry: 1.0
species: 458794

505951
type: SpeciesReference
stoichiometry: 1.0
species: 464639

505963
type: SpeciesReference
stoichiometry: 1.0
species: 455606

455606
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

505999
type: SpeciesReference
stoichiometry: 1.0
species: 464711

505975
type: SpeciesReference
stoichiometry: 2.0
species: 451828

451828
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

460133
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Iodide_I

457271
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: GDP-L-fucose_C16H23N5O15P2

992449
type: Reaction
is: http://identifiers.org/ec-code/4.1.1.36
name: phosphopantothenoylcysteine decarboxylase
fast: false
product: 519655
reactant: 519619
reversible: false
product: 519643
is: ENSBTAG00000014089.3
reactant: 519631
notes: R_PPCDC subsystem: CoA Biosynthesis R_PPCDC equation: [c] : 4ppcys + h --> co2 + pan4p

519655
type: SpeciesReference
stoichiometry: 1.0
species: 451519

519619
type: SpeciesReference
stoichiometry: 1.0
species: 445866

445866
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-((R)-4-Phosphopantothenoyl)-L-cysteine_C12H20N2O9PS

519643
type: SpeciesReference
stoichiometry: 1.0
species: 466178

466178
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Pantetheine 4'-phosphate_C11H21N2O7PS

519631
type: SpeciesReference
stoichiometry: 1.0
species: 458794

464386
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: reducing GlcNAc removed form of n2m2nmasn (w/o peptide)_C50H84N4O36

989363
type: Reaction
modifier: 491438
notes: R_L_DASH_LACtcm subsystem: Transport, Mitochondrial R_L_DASH_LACtcm equation: lac-L[c] --> lac-L[m] R_UREAtm subsystem: Urea cycle/amino group metabolism R_UREAtm equation: urea[c] <==> urea[m]
is: ENSBTAG00000013452.4
fast: false
reversible: false
modifier: 491426
reactant: 491402
product: 491414

491402
type: SpeciesReference
stoichiometry: 1.0
species: 462174

491414
type: SpeciesReference
stoichiometry: 1.0
species: 462198

468683
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: sulfatide galactocerebroside (homo sapiens)_C24H45NO10SFULLRCO

997354
type: Reaction
name: cardiolipin synthase (homo sapiens)
product: 566830
reactant: 566781
reversible: false
product: 566805
product: 566818
notes: R_CLS_hs subsystem: Glycerophospholipid Metabolism R_CLS_hs equation: [c] : cdpdag_hs + pglyc_hs --> clpn_hs + cmp + h
is: ENSBTAG00000000065.4
fast: false
reactant: 566793

566830
type: SpeciesReference
stoichiometry: 1.0
species: 458794

566781
type: SpeciesReference
stoichiometry: 1.0
species: 466531

566805
type: SpeciesReference
stoichiometry: 1.0
species: 451398

566818
type: SpeciesReference
stoichiometry: 1.0
species: 451301

451301
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: cardiolipin (homo sapiens)_C9H16O9P2FULLRCO2FULLR2CO2FULLRCO2FULLR2CO2

566793
type: SpeciesReference
stoichiometry: 1.0
species: 450781

992725
type: Reaction
reactant: 521682
fast: false
reactant: 521706
is: http://identifiers.org/ec-code/4.1.1.28
reactant: 521633
reversible: false
product: 521778
reactant: 521609
product: 521790
product: 521718
is: http://identifiers.org/ec-code/4.1.1.22
product: 521730
reactant: 521670
is: http://identifiers.org/ec-code/4.1.1.25
product: 521815
product: 521803
product: 521754
product: 521742
reactant: 521645
is: ENSBTAG00000020869.4
product: 521766
reactant: 521621
reactant: 521694
notes: R_5HXKYNDCL subsystem: Tryptophan metabolism R_5HXKYNDCL equation: [c] : 5hxkyn + h --> 5hxkynam + co2 R_HISDC subsystem: Histidine Metabolism R_HISDC equation: [c] : h + his-L --> co2 + hista R_TYRCBOX subsystem: Tyrosine metabolism R_TYRCBOX equation: [c] : h + tyr-L --> co2 + tym R_5HLTDL subsystem: Tryptophan metabolism R_5HLTDL equation: [c] : 5htrp + h --> co2 + srtn R_PHYCBOXL subsystem: Phenylalanine metabolism R_PHYCBOXL equation: [c] : h + phe-L --> co2 + peamn R_LTDCL subsystem: Tryptophan metabolism R_LTDCL equation: [c] : h + trp-L --> co2 + trypta R_3HXKYNDCL subsystem: Tryptophan metabolism R_3HXKYNDCL equation: [c] : h + hLkynr --> 3hxkynam + co2 R_3HLYTCL subsystem: Tyrosine metabolism R_3HLYTCL equation: [c] : 34dhphe + h --> co2 + dopa
reactant: 521658

521682
type: SpeciesReference
stoichiometry: 1.0
species: 470361

521706
type: SpeciesReference
stoichiometry: 8.0
species: 458794

521633
type: SpeciesReference
stoichiometry: 1.0
species: 444695

444695
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3,4-Dihydroxy-L-phenylalanine_C9H11NO4

521778
type: SpeciesReference
stoichiometry: 1.0
species: 445071

445071
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Hydroxykynurenamine_C9H13N2O2

521609
type: SpeciesReference
stoichiometry: 1.0
species: 458782

458782
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Hydroxy-L-kynurenine_C10H12N2O4

521790
type: SpeciesReference
stoichiometry: 1.0
species: 459313

521718
type: SpeciesReference
stoichiometry: 1.0
species: 470385

470385
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Tryptamine_C10H13N2

521730
type: SpeciesReference
stoichiometry: 1.0
species: 470579

470579
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Tyramine_C8H12NO

521670
type: SpeciesReference
stoichiometry: 1.0
species: 446274

521815
type: SpeciesReference
stoichiometry: 1.0
species: 454523

521803
type: SpeciesReference
stoichiometry: 8.0
species: 451519

521754
type: SpeciesReference
stoichiometry: 1.0
species: 446310

446310
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-Hydroxykynurenamine_C9H13N2O2

521742
type: SpeciesReference
stoichiometry: 1.0
species: 466435

466435
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Phenethylamine_C8H12N

521645
type: SpeciesReference
stoichiometry: 1.0
species: 446298

446298
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-Hydroxykynurenine_C10H12N2O4

521766
type: SpeciesReference
stoichiometry: 1.0
species: 468984

521621
type: SpeciesReference
stoichiometry: 1.0
species: 459289

459289
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Histidine_C6H9N3O2

521694
type: SpeciesReference
stoichiometry: 1.0
species: 466567

521658
type: SpeciesReference
stoichiometry: 1.0
species: 470603

470603
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Tyrosine_C9H11NO3

465051
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Nitric oxide_NO

453156
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: dCMP_C9H12N3O7P

444358
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-2-Amino-3-oxobutanoate_C4H7NO3

454619
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Desmosterol_C27H44O

456994
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N1-(5-Phospho-D-ribosyl)glycinamide_C7H14N2O8P

458891
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: hyaluronan degradation product 1_C22H33N2O16

989198
type: Reaction
product: 490084
reactant: 490072
notes: R_ACGAMPM subsystem: Aminosugar Metabolism R_ACGAMPM equation: [c] : acgam6p <==> acgam1p
is: ENSBTAG00000000679.4
is: http://identifiers.org/ec-code/5.4.2.3
fast: false
reversible: true
name: phosphoacetylglucosamine mutase

490084
type: SpeciesReference
stoichiometry: 1.0
species: 447919

447919
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Acetyl-D-glucosamine 1-phosphate_C8H14NO9P

490072
type: SpeciesReference
stoichiometry: 1.0
species: 447931

990768
type: Reaction
product: 502916
reactant: 502880
reactant: 502868
is: ENSBTAG00000017676.3
is: http://identifiers.org/ec-code/2.7.6.2
product: 502904
notes: R_TMDPK subsystem: Thiamine Metabolism R_TMDPK equation: [c] : atp + thm --> amp + h + thmpp
reversible: false
name: thiamine diphosphokinase
product: 502892
fast: false

502916
type: SpeciesReference
stoichiometry: 1.0
species: 458794

502880
type: SpeciesReference
stoichiometry: 1.0
species: 469927

502868
type: SpeciesReference
stoichiometry: 1.0
species: 449983

502904
type: SpeciesReference
stoichiometry: 1.0
species: 449296

502892
type: SpeciesReference
stoichiometry: 1.0
species: 469975

469975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Thiamine diphosphate_C12H16N4O7P2S

995964
type: Reaction
product: 553967
is: http://identifiers.org/ec-code/6.2.1.13
fast: false
reactant: 553918
is: http://identifiers.org/ec-code/6.2.1.1
reactant: 553882
notes: R_ACS2 subsystem: Propanoate Metabolism R_ACS2 equation: [c] : atp + coa + ppa --> amp + ppcoa + ppi R_ACCOAL subsystem: Propanoate Metabolism R_ACCOAL equation: [c] : atp + coa + ppa --> adp + pi + ppcoa R_ACS subsystem: Glycolysis/Gluconeogenesis R_ACS equation: [c] : ac + atp + coa --> accoa + amp + ppi
reversible: false
product: 553980
is: ENSBTAG00000013303.4
reactant: 553906
reactant: 553894
product: 553943
product: 553993
product: 553955
product: 553930

553967
type: SpeciesReference
stoichiometry: 1.0
species: 447665

553918
type: SpeciesReference
stoichiometry: 2.0
species: 466928

466928
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Propionate (n-C3:0)_C3H5O2

553882
type: SpeciesReference
stoichiometry: 3.0
species: 451593

553980
type: SpeciesReference
stoichiometry: 2.0
species: 449296

553906
type: SpeciesReference
stoichiometry: 3.0
species: 449983

553894
type: SpeciesReference
stoichiometry: 1.0
species: 447521

553943
type: SpeciesReference
stoichiometry: 1.0
species: 448462

553993
type: SpeciesReference
stoichiometry: 2.0
species: 467000

553955
type: SpeciesReference
stoichiometry: 2.0
species: 466964

466964
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Propanoyl-CoA_C24H36N7O17P3S

553930
type: SpeciesReference
stoichiometry: 1.0
species: 466736

455052
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: eicosatetranoic acid_C20H31O2

447374
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: trans-4-Hydroxycinnamate_C9H7O3

444443
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _2-Deoxy-D-ribose 1-phosphate_C5H9O7P

453432
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: all trans Decaprenyl diphosphate_C50H81O7P2

988718
type: Reaction
reactant: 485197
reversible: false
product: 485305
reactant: 485161
reactant: 485209
modifier: 485378
reactant: 485149
modifier: 485342
product: 485293
product: 485281
reactant: 485185
reactant: 485137
product: 485245
product: 485221
modifier: 485317
modifier: 485390
modifier: 485366
fast: false
product: 485233
reactant: 485125
is: http://identifiers.org/ec-code/6.2.1.2
modifier: 485402
modifier: 485354
modifier: 485330
product: 485257
is: ENSBTAG00000017258.4
is: http://identifiers.org/ec-code/6.2.1.3
notes: R_FACOAL180i subsystem: Fatty acid activation R_FACOAL180i equation: [c] : atp + coa + ocdca --> amp + ppi + stcoa R_FACOAL181i subsystem: Fatty acid activation R_FACOAL181i equation: [c] : atp + coa + ocdcea --> amp + odecoa + ppi R_FACOAL150 subsystem: Fatty acid activation R_FACOAL150 equation: [c] : atp + coa + ptdca <==> amp + ppi + ptdcacoa R_FACOAL160i subsystem: Fatty acid activation R_FACOAL160i equation: [c] : atp + coa + hdca --> amp + pmtcoa + ppi R_FACOAL204i subsystem: Fatty acid activation R_FACOAL204i equation: [c] : arachd + atp + coa --> amp + arachdcoa + ppi R_FACOAL170 subsystem: Fatty acid activation R_FACOAL170 equation: [c] : atp + coa + hpdca <==> amp + hpdcacoa + ppi R_FACOAL80i subsystem: Fatty acid activation R_FACOAL80i equation: [c] : atp + coa + octa --> amp + occoa + ppi R_FACOAL140i subsystem: Fatty acid activation R_FACOAL140i equation: [c] : atp + coa + ttdca --> amp + ppi + tdcoa
reactant: 485173
product: 485269

485197
type: SpeciesReference
stoichiometry: 1.0
species: 465523

465523
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: octadecenoate (n-C18:1)_C18H33O2

485305
type: SpeciesReference
stoichiometry: 6.0
species: 467000

485161
type: SpeciesReference
stoichiometry: 1.0
species: 449693

449693
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: arachidonic acid_C20H31O2

485209
type: SpeciesReference
stoichiometry: 1.0
species: 465573

465573
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: octanoate (n-C8:0)_C8H15O2

459445
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: heptadecanoate_C17H33O2

485149
type: SpeciesReference
stoichiometry: 6.0
species: 451593

485293
type: SpeciesReference
stoichiometry: 6.0
species: 449296

485281
type: SpeciesReference
stoichiometry: 1.0
species: 465451

465451
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Octanoyl-CoA (n-C8:0CoA)_C29H46N7O17P3S

485185
type: SpeciesReference
stoichiometry: 1.0
species: 465499

465499
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: octadecanoate (n-C18:0)_C18H35O2

485137
type: SpeciesReference
stoichiometry: 1.0
species: 470519

470519
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: tetradecanoate (n-C14:0)_C14H27O2

485245
type: SpeciesReference
stoichiometry: 1.0
species: 469455

469455
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Tetradecanoyl-CoA (n-C14:0CoA)_C35H58N7O17P3S

485221
type: SpeciesReference
stoichiometry: 1.0
species: 449729

467741
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: pentadecanoyl Coenzyme A_C36H60N7O17P3S

485233
type: SpeciesReference
stoichiometry: 1.0
species: 465621

465621
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Octadecenoyl-CoA (n-C18:1CoA)_C39H64N7O17P3S

485125
type: SpeciesReference
stoichiometry: 1.0
species: 459013

459013
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Hexadecanoate (n-C16:0)_C16H31O2

459457
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: heptadecanoyl coa_C38H64N7O17P3S

467728
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: pentadecanoate_C15H29O2

485257
type: SpeciesReference
stoichiometry: 1.0
species: 466832

466832
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S

485173
type: SpeciesReference
stoichiometry: 6.0
species: 449983

485269
type: SpeciesReference
stoichiometry: 1.0
species: 469008

469008
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S

461763
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate II (core 2-linked)_C81H129N6O67S3X

988334
type: Reaction
reversible: false
product: 481522
product: 481474
product: 481450
product: 481498
notes: R_ST8SIA53g subsystem: Sphingolipid Metabolism R_ST8SIA53g equation: [g] : cmpacna + gd1a_hs --> cmp + gt1a_hs + h R_ST8SIA51g subsystem: Sphingolipid Metabolism R_ST8SIA51g equation: [g] : cmpacna + gd3_hs --> cmp + gt3_hs + h R_ST8SIA56g subsystem: Blood Group Biosynthesis R_ST8SIA56g equation: [g] : acngal14acglcgalgluside_hs + cmpacna --> acnacngal14acglcgalgluside_hs + cmp + h R_ST8SIA52g subsystem: Sphingolipid Metabolism R_ST8SIA52g equation: [g] : cmpacna + gt1b_hs --> cmp + gq1b_hs + h R_ST8SIA54g subsystem: Sphingolipid Metabolism R_ST8SIA54g equation: [g] : cmpacna + gm1b_hs --> cmp + gd1c_hs + h R_ST8SIA55g subsystem: Sphingolipid Metabolism R_ST8SIA55g equation: [g] : cmpacna + gq1c_hs --> cmp + gp1calpha_hs + h
reactant: 481390
product: 481438
reactant: 481366
product: 481510
product: 481486
reactant: 481378
is: http://identifiers.org/ec-code/2.4.99.8
product: 481462
is: ENSBTAG00000001770.4
reactant: 481414
reactant: 481402
reactant: 481426
reactant: 481354
fast: false

481522
type: SpeciesReference
stoichiometry: 1.0
species: 458408

458408
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GT3 (homo sapiens)_C63H104N4O36FULLRCO

481474
type: SpeciesReference
stoichiometry: 6.0
species: 458819

481450
type: SpeciesReference
stoichiometry: 1.0
species: 458336

458336
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GT1a (homo sapiens)_C77H127N5O46FULLRCO

481498
type: SpeciesReference
stoichiometry: 1.0
species: 457139

457139
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GD1c (homo sapiens)_C66H111N4O38FULLRCO

481390
type: SpeciesReference
stoichiometry: 1.0
species: 448232

481438
type: SpeciesReference
stoichiometry: 1.0
species: 458167

458167
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GP1c alpha (homo sapiens)_C99H159N7O62FULLRCO

481366
type: SpeciesReference
stoichiometry: 1.0
species: 458021

458021
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GM1b (homo sapiens)_C55H95N3O30FULLRCO

481510
type: SpeciesReference
stoichiometry: 1.0
species: 458227

458227
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GQ1b (homo sapiens)_C88H143N6O54FULLRCO

481486
type: SpeciesReference
stoichiometry: 6.0
species: 451422

481378
type: SpeciesReference
stoichiometry: 6.0
species: 451471

481462
type: SpeciesReference
stoichiometry: 1.0
species: 448160

448160
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: _3',8'-LD1_C66H111N4O38FULLRCO

481414
type: SpeciesReference
stoichiometry: 1.0
species: 458360

458360
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GT1b (homo sapiens)_C77H127N5O46FULLRCO

481402
type: SpeciesReference
stoichiometry: 1.0
species: 458251

458251
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GQ1c (homo sapiens)_C88H143N6O54FULLRCO

481426
type: SpeciesReference
stoichiometry: 1.0
species: 457175

457175
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GD3 (homo sapiens)_C52H88N3O28FULLRCO

481354
type: SpeciesReference
stoichiometry: 1.0
species: 457091

457091
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GD1a (homo sapiens)_C66H111N4O38FULLRCO

990468
type: Reaction
notes: R_L_DASH_LACDcm subsystem: Pyruvate Metabolism R_L_DASH_LACDcm equation: (2) ficytC[m] + lac-L[c] --> (2) focytC[m] + (2) h[c] + pyr[c]
reactant: 500712
product: 500748
is: http://identifiers.org/ec-code/1.1.2.3
name: L-Lactate dehydrogenase, cytosolic/mitochondrial
product: 500736
product: 500760
is: ENSBTAG00000014696.3
fast: false
reversible: false
reactant: 500724

500712
type: SpeciesReference
stoichiometry: 2.0
species: 455775

500748
type: SpeciesReference
stoichiometry: 1.0
species: 467909

500736
type: SpeciesReference
stoichiometry: 2.0
species: 455823

500760
type: SpeciesReference
stoichiometry: 2.0
species: 458794

500724
type: SpeciesReference
stoichiometry: 1.0
species: 462174

450190
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Bilirubin monoglucuronide_C39H44N4O12

997904
type: Reaction
product: 573008
reversible: false
reactant: 572996
product: 573020
is: ENSBTAG00000030201.2
reactant: 572984
is: ENSBTAG00000007379.4
is: http://identifiers.org/ec-code/3.5.1.23
name: N-acylsphingosine amidohydrolase
notes: R_ASAH1 subsystem: Sphingolipid Metabolism R_ASAH1 equation: [l] : crm_hs + h2o --> Rtotal + sphings
fast: false

573008
type: SpeciesReference
stoichiometry: 1.0
species: 468863

468863
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Sphingosine_C18H38NO2

572996
type: SpeciesReference
stoichiometry: 1.0
species: 458721

573020
type: SpeciesReference
stoichiometry: 1.0
species: 447226

447226
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: R total_CO2FULLR

572984
type: SpeciesReference
stoichiometry: 1.0
species: 451852

451852
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

993217
type: Reaction
is: http://identifiers.org/ec-code/2.8.2.23
is: ENSBTAG00000017391.4
reactant: 526589
notes: R_S3T2g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T2g equation: [g] : hs_pre14 + paps --> h + hs_pre15 + pap
reversible: false
name: heparin-glucosamine 3-O-sulfotransferase
product: 526638
product: 526626
reactant: 526601
product: 526614
fast: false

526589
type: SpeciesReference
stoichiometry: 1.0
species: 466226

526638
type: SpeciesReference
stoichiometry: 1.0
species: 466202

526626
type: SpeciesReference
stoichiometry: 1.0
species: 459902

526601
type: SpeciesReference
stoichiometry: 1.0
species: 459890

459890
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: heparan sulfate, precursor 14_C79H115N5O95S10X

526614
type: SpeciesReference
stoichiometry: 1.0
species: 458819

471396
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: omega hydroxy tetradecanoate (n-C14:0)_C14H27O3

453566
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Deoxyguanosine_C10H13N5O4

992473
type: Reaction
product: 519777
is: http://identifiers.org/ec-code/2.1.1.6
notes: R_SALMCOM2 subsystem: Tyrosine metabolism R_SALMCOM2 equation: [c] : adrnl + amet --> ahcys + h + mepi R_SALMCOM subsystem: Tyrosine metabolism R_SALMCOM equation: [c] : amet + nrpphr --> ahcys + h + normete-L
product: 519816
reactant: 519764
reactant: 519740
product: 519790
reversible: false
reactant: 519752
product: 519803
fast: false
is: ENSBTAG00000012977.4

519777
type: SpeciesReference
stoichiometry: 2.0
species: 448813

519816
type: SpeciesReference
stoichiometry: 2.0
species: 458794

519764
type: SpeciesReference
stoichiometry: 1.0
species: 448705

519740
type: SpeciesReference
stoichiometry: 1.0
species: 465087

519790
type: SpeciesReference
stoichiometry: 1.0
species: 465063

519752
type: SpeciesReference
stoichiometry: 2.0
species: 449236

519803
type: SpeciesReference
stoichiometry: 1.0
species: 463757

463757
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Metanephrine_C10H16NO3

997406
type: Reaction
product: 568653
reversible: true
fast: false
reactant: 568593
reactant: 568617
product: 568641
is: http://identifiers.org/ec-code/2.4.2.2
reactant: 568605
is: ENSBTAG00000012801.3
notes: R_DURIPP subsystem: Nucleotides R_DURIPP equation: [c] : duri + pi <==> 2dr1p + ura R_PYNP2r subsystem: Pyrimidine Catabolism R_PYNP2r equation: [c] : pi + uri <==> r1p + ura
product: 568629

568653
type: SpeciesReference
stoichiometry: 2.0
species: 471035

568593
type: SpeciesReference
stoichiometry: 1.0
species: 454860

568617
type: SpeciesReference
stoichiometry: 1.0
species: 471119

568641
type: SpeciesReference
stoichiometry: 1.0
species: 468018

468018
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: alpha-D-Ribose 1-phosphate_C5H9O8P

568605
type: SpeciesReference
stoichiometry: 2.0
species: 466736

568629
type: SpeciesReference
stoichiometry: 1.0
species: 444443

991356
type: Reaction
is: http://identifiers.org/ec-code/1.8.1.7
product: 509280
notes: R_GTHO subsystem: Glutamate metabolism R_GTHO equation: [c] : gthox + h + nadph --> (2) gthrd + nadp R_GTHOm subsystem: Glutamate metabolism R_GTHOm equation: [m] : gthox + h + nadph --> (2) gthrd + nadp
reactant: 509244
reversible: false
product: 509256
product: 509268
reactant: 509196
reactant: 509208
fast: false
reactant: 509184
reactant: 509220
is: ENSBTAG00000021417.4
product: 509292
reactant: 509232

509280
type: SpeciesReference
stoichiometry: 2.0
species: 458480

458480
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Reduced glutathione_C10H16N3O6S

509244
type: SpeciesReference
stoichiometry: 1.0
species: 464711

509256
type: SpeciesReference
stoichiometry: 1.0
species: 464639

509268
type: SpeciesReference
stoichiometry: 2.0
species: 458456

458456
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Reduced glutathione_C10H16N3O6S

509196
type: SpeciesReference
stoichiometry: 1.0
species: 458444

458444
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Oxidized glutathione_C20H30N6O12S2

509208
type: SpeciesReference
stoichiometry: 1.0
species: 464723

509184
type: SpeciesReference
stoichiometry: 1.0
species: 458420

458420
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Oxidized glutathione_C20H30N6O12S2

509220
type: SpeciesReference
stoichiometry: 1.0
species: 458843

509292
type: SpeciesReference
stoichiometry: 1.0
species: 464663

509232
type: SpeciesReference
stoichiometry: 1.0
species: 458794

994547
type: Reaction
reactant: 540791
fast: false
reversible: false
reactant: 540778
is: ENSBTAG00000005744.4
product: 540815
product: 540803
name: Hydroxybenzoate Decaprenyltransferase
notes: R_HBZOPT10m subsystem: Ubiquinone Biosynthesis R_HBZOPT10m equation: [m] : 4hbz + decdp --> 3dphb + ppi

540791
type: SpeciesReference
stoichiometry: 1.0
species: 445637

445637
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _4-Hydroxybenzoate_C7H5O3

540778
type: SpeciesReference
stoichiometry: 1.0
species: 453432

540815
type: SpeciesReference
stoichiometry: 1.0
species: 467012

540803
type: SpeciesReference
stoichiometry: 1.0
species: 444865

445818
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-Nitrophenol_C6H5NO3

447348
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: S-Formylglutathione_C11H16N3O7S

468647
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Serine_C3H7NO3

450938
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Choline_C5H14NO

455232
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: estradiol glucuronide_C24H32O8

447894
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)3 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)1 (Cer)1_C72H125N4O41FULLRCO

459001
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Homocysteine_C4H9NO2S

448608
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: adrenic acid_C22H35O2

467255
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: pregnenolone sulfate_C21H31O5S

455835
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Folate_C19H18N7O6

452879
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Deoxyadenosine_C10H13N5O3

994251
type: Reaction
modifier: 536999
modifier: 536974
notes: R_NDP8 subsystem: Nucleotides R_NDP8 equation: [c] : dudp + h2o --> dump + h + pi R_DTMPK subsystem: Nucleotides R_DTMPK equation: [c] : atp + dtmp <==> adp + dtdp
is: ENSBTAG00000015408.3
reversible: false
reactant: 536910
is: http://identifiers.org/ec-code/2.7.4.9
is: http://identifiers.org/ec-code/3.6.1.6
reactant: 536896
product: 536949
product: 536923
modifier: 536986
product: 536936
fast: false
modifier: 536962

454691
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dTMP_C10H13N2O8P

454643
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dTDP_C10H13N2O11P2

536910
type: SpeciesReference
stoichiometry: 1.0
species: 458685

536896
type: SpeciesReference
stoichiometry: 1.0
species: 454788

536949
type: SpeciesReference
stoichiometry: 1.0
species: 458794

536923
type: SpeciesReference
stoichiometry: 1.0
species: 466736

536936
type: SpeciesReference
stoichiometry: 1.0
species: 454824

454824
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dUMP_C9H11N2O8P

993518
type: Reaction
product: 529155
reactant: 528974
product: 529034
reactant: 528998
reactant: 528890
product: 529106
product: 529070
notes: R_ALAASNNaEx subsystem: Transport, Extracellular R_ALAASNNaEx equation: ala-L[e] + asn-L[c] + na1[e] --> ala-L[c] + asn-L[e] + na1[c] R_SERASNNaEx subsystem: Transport, Extracellular R_SERASNNaEx equation: asn-L[c] + na1[e] + ser-L[e] --> asn-L[e] + na1[c] + ser-L[c] R_GLNSERNaEx subsystem: Transport, Extracellular R_GLNSERNaEx equation: gln-L[e] + na1[e] + ser-L[c] --> gln-L[c] + na1[c] + ser-L[e] R_SERGLNNaEx subsystem: Transport, Extracellular R_SERGLNNaEx equation: gln-L[c] + na1[e] + ser-L[e] --> gln-L[e] + na1[c] + ser-L[c] R_CYSTHRNaEx subsystem: Transport, Extracellular R_CYSTHRNaEx equation: cys-L[e] + na1[e] + thr-L[c] --> cys-L[c] + na1[c] + thr-L[e] R_ASNGLNNaEx subsystem: Transport, Extracellular R_ASNGLNNaEx equation: asn-L[e] + gln-L[c] + na1[e] --> asn-L[c] + gln-L[e] + na1[c] R_GLNTHRNaEx subsystem: Transport, Extracellular R_GLNTHRNaEx equation: gln-L[e] + na1[e] + thr-L[c] --> gln-L[c] + na1[c] + thr-L[e] R_ASNTHRNaEx subsystem: Transport, Extracellular R_ASNTHRNaEx equation: asn-L[e] + na1[e] + thr-L[c] --> asn-L[c] + na1[c] + thr-L[e] R_THRSERNaEx subsystem: Transport, Extracellular R_THRSERNaEx equation: na1[e] + ser-L[c] + thr-L[e] --> na1[c] + ser-L[e] + thr-L[c] R_ALACYSNaEx subsystem: Transport, Extracellular R_ALACYSNaEx equation: ala-L[e] + cys-L[c] + na1[e] --> ala-L[c] + cys-L[e] + na1[c] R_GLNCYSNaEx subsystem: Transport, Extracellular R_GLNCYSNaEx equation: cys-L[c] + gln-L[e] + na1[e] --> cys-L[e] + gln-L[c] + na1[c] R_THRALANaEx subsystem: Transport, Extracellular R_THRALANaEx equation: ala-L[c] + na1[e] + thr-L[e] --> ala-L[e] + na1[c] + thr-L[c] R_GLNASNNaEx subsystem: Transport, Extracellular R_GLNASNNaEx equation: asn-L[c] + gln-L[e] + na1[e] --> asn-L[e] + gln-L[c] + na1[c] R_CYSALANaEx subsystem: Transport, Extracellular R_CYSALANaEx equation: ala-L[c] + cys-L[e] + na1[e] --> ala-L[e] + cys-L[c] + na1[c] R_CYSGLNNaEx subsystem: Transport, Extracellular R_CYSGLNNaEx equation: cys-L[e] + gln-L[c] + na1[e] --> cys-L[c] + gln-L[e]…
product: 529143
is: ENSBTAG00000013502.4
product: 529167
product: 529094
reversible: false
product: 529119
reactant: 529010
product: 529046
reactant: 528902
reactant: 528878
reactant: 528866
product: 529022
reactant: 528926
reactant: 528914
is: ENSBTAG00000013577.4
fast: false
reactant: 528938
reactant: 528962
reactant: 528950
product: 529131
reactant: 528986
product: 529082
product: 529058

529155
type: SpeciesReference
stoichiometry: 5.0
species: 468635

468635
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Serine_C3H7NO3

528974
type: SpeciesReference
stoichiometry: 5.0
species: 470023

529034
type: SpeciesReference
stoichiometry: 5.0
species: 468623

468623
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Serine_C3H7NO3

528998
type: SpeciesReference
stoichiometry: 5.0
species: 449091

528890
type: SpeciesReference
stoichiometry: 5.0
species: 449103

449103
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Alanine_C3H7NO2

529106
type: SpeciesReference
stoichiometry: 5.0
species: 449874

529070
type: SpeciesReference
stoichiometry: 5.0
species: 457464

529143
type: SpeciesReference
stoichiometry: 5.0
species: 457476

457476
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Glutamine_C5H10N2O3

529167
type: SpeciesReference
stoichiometry: 5.0
species: 449091

529094
type: SpeciesReference
stoichiometry: 30.0
species: 464458

529119
type: SpeciesReference
stoichiometry: 5.0
species: 470035

470035
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Threonine_C4H9NO3

529010
type: SpeciesReference
stoichiometry: 5.0
species: 468635

529046
type: SpeciesReference
stoichiometry: 5.0
species: 449103

528902
type: SpeciesReference
stoichiometry: 5.0
species: 452771

528878
type: SpeciesReference
stoichiometry: 5.0
species: 468623

528866
type: SpeciesReference
stoichiometry: 5.0
species: 452759

529022
type: SpeciesReference
stoichiometry: 5.0
species: 452759

528926
type: SpeciesReference
stoichiometry: 5.0
species: 449886

528914
type: SpeciesReference
stoichiometry: 5.0
species: 457464

528938
type: SpeciesReference
stoichiometry: 30.0
species: 464470

528962
type: SpeciesReference
stoichiometry: 5.0
species: 470035

528950
type: SpeciesReference
stoichiometry: 5.0
species: 449874

529131
type: SpeciesReference
stoichiometry: 5.0
species: 470023

528986
type: SpeciesReference
stoichiometry: 5.0
species: 457476

529082
type: SpeciesReference
stoichiometry: 5.0
species: 449886

529058
type: SpeciesReference
stoichiometry: 5.0
species: 452771

449789
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: D-Arginine_C6H15N4O2

444805
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-3-Amino-isobutanoate_C4H9NO2

467389
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: D-Proline_C5H9NO2

990492
type: Reaction
reversible: true
is: ENSBTAG00000015074.4
is: ENSBTAG00000017073.4
fast: false
reactant: 500821
product: 500845
product: 500857
reactant: 500833
is: http://identifiers.org/ec-code/5.3.99.2
notes: R_PGDIr subsystem: Eicosanoid Metabolism R_PGDIr equation: [r] : prostgh2 <==> prostgd2 R_PGDI subsystem: Eicosanoid Metabolism R_PGDI equation: [c] : prostgh2 <==> prostgd2

500821
type: SpeciesReference
stoichiometry: 1.0
species: 467620

467620
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Prostaglandin H2_C20H31O5

500845
type: SpeciesReference
stoichiometry: 1.0
species: 467510

500857
type: SpeciesReference
stoichiometry: 1.0
species: 467486

500833
type: SpeciesReference
stoichiometry: 1.0
species: 467607

467607
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Prostaglandin H2_C20H31O5

461727
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate II (core 2-linked), degradation product 8_C36H60N3O25X

993241
type: Reaction
notes: R_C14STRr subsystem: Cholesterol Metabolism R_C14STRr equation: [r] : 44mctr + h + nadph --> 44mzym + nadp
reversible: false
reactant: 526734
product: 526758
is: http://identifiers.org/ec-code/1.3.1.70
reactant: 526722
name: C-14 sterol reductase
is: ENSBTAG00000005069.3
product: 526746
reactant: 526710
fast: false

526734
type: SpeciesReference
stoichiometry: 1.0
species: 445456

445456
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _4,4-dimethylcholesta-8,14,24-trienol_C29H46O

526758
type: SpeciesReference
stoichiometry: 1.0
species: 464687

526722
type: SpeciesReference
stoichiometry: 1.0
species: 458867

526746
type: SpeciesReference
stoichiometry: 1.0
species: 445468

445468
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _4,4-dimethylzymosterol_C29H48O

526710
type: SpeciesReference
stoichiometry: 1.0
species: 464747

995736
type: Reaction
product: 551696
product: 551684
product: 551672
fast: false
is: ENSBTAG00000013527.4
reactant: 551648
notes: R_GND subsystem: Pentose Phosphate Pathway R_GND equation: [c] : 6pgc + nadp --> co2 + nadph + ru5p-D
is: http://identifiers.org/ec-code/1.1.1.44
reactant: 551660
name: phosphogluconate dehydrogenase
reversible: false

551696
type: SpeciesReference
stoichiometry: 1.0
species: 464711

551684
type: SpeciesReference
stoichiometry: 1.0
species: 451519

551672
type: SpeciesReference
stoichiometry: 1.0
species: 468237

468237
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Ribulose 5-phosphate_C5H9O8P

551648
type: SpeciesReference
stoichiometry: 1.0
species: 464639

551660
type: SpeciesReference
stoichiometry: 1.0
species: 446526

446526
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _6-Phospho-D-gluconate_C6H10O10P

468054
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: fatty acid retinol_C20H29OFULLR2CO

467704
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: phosphatidylserine (homo sapiens)_C6H11NO6PFULLRCO2FULLR2CO2

450019
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: ATP_C10H12N5O13P3

992509
type: Reaction
notes: R_FUCASEe subsystem: N-Glycan Degradation R_FUCASEe equation: [e] : h2o + s2l2fn2m2masn --> fuc-L + s2l2n2m2masn R_FUCASE2e subsystem: Keratan sulfate degradation R_FUCASE2e equation: [e] : h2o + ksi --> fuc-L + ksi_deg1
reactant: 519999
is: ENSBTAG00000001626.4
reactant: 519975
fast: false
is: http://identifiers.org/ec-code/3.2.1.51
reversible: false
product: 520035
product: 520023
product: 520011
reactant: 519987

519999
type: SpeciesReference
stoichiometry: 1.0
species: 468249

468249
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: PA6_C90H145N6O65X

519975
type: SpeciesReference
stoichiometry: 2.0
species: 458697

520035
type: SpeciesReference
stoichiometry: 1.0
species: 468309

468309
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: de-Fuc form of PA6_C84H135N6O61X

520023
type: SpeciesReference
stoichiometry: 2.0
species: 456100

456100
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Fucose_C6H12O5

520011
type: SpeciesReference
stoichiometry: 1.0
species: 460775

460775
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: keratan sulfate I, degradation product 1_C241H383N17O209S12X

519987
type: SpeciesReference
stoichiometry: 1.0
species: 461165

461165
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: keratan sulfate I_C247H393N17O213S12X

460376
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: IMP_C10H11N4O8P

470999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: UMP_C9H11N2O9P

461129
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 7_C210H337N15O181S10

468188
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: retinoyl glucuronide_C26H35O8

469793
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695

456785
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)3 (Glc)1 (GlcNAc)1 (LFuc)1 (Cer)1_C56H99N2O31FULLRCO

454764
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: dTTP_C10H13N2O14P3

452311
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 1_C45H66N2O49S4

997341
type: Reaction
product: 566769
product: 566745
fast: false
is: ENSBTAG00000005304.4
reactant: 566721
reactant: 566733
notes: R_SPMS subsystem: Urea cycle/amino group metabolism R_SPMS equation: [c] : ametam + ptrc --> 5mta + h + spmd
name: spermidine synthase
reversible: false
is: http://identifiers.org/ec-code/2.5.1.16
product: 566757

566769
type: SpeciesReference
stoichiometry: 1.0
species: 458794

566745
type: SpeciesReference
stoichiometry: 1.0
species: 446346

446346
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-Methylthioadenosine_C11H15N5O3S

566721
type: SpeciesReference
stoichiometry: 1.0
species: 467789

566733
type: SpeciesReference
stoichiometry: 1.0
species: 449284

449284
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: S-Adenosylmethioninamine_C14H24N6O3S

566757
type: SpeciesReference
stoichiometry: 1.0
species: 468948

468948
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Spermidine_C7H22N3

466772
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Phosphate_HO4P

461675
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate II (core 2-linked), degradation product 4_C58H95N5O43SX

W3 CDTF: Fri Feb 03 12:44:18 GMT 2012

471432
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Xanthosine 5'-phosphate_C10H11N4O9P

988118
type: Reaction
product: 479503
reactant: 479383
reactant: 479347
product: 479467
product: 479539
reactant: 479395
notes: R_D_DASH_LACt2 subsystem: Transport, Extracellular R_D_DASH_LACt2 equation: h[e] + lac-D[e] <==> h[c] + lac-D[c] R_L_DASH_LACt2r subsystem: Transport, Extracellular R_L_DASH_LACt2r equation: h[e] + lac-L[e] <==> h[c] + lac-L[c] R_ACACt2 subsystem: Transport, Extracellular R_ACACt2 equation: acac[e] + h[e] <==> acac[c] + h[c] R_PYRt2r subsystem: Transport, Extracellular R_PYRt2r equation: h[e] + pyr[e] <==> h[c] + pyr[c] R_ACETONEt2 subsystem: Transport, Extracellular R_ACETONEt2 equation: acetone[e] + h[e] <==> acetone[c] + h[c] R_PYRt2p subsystem: D-alanine metabolism R_PYRt2p equation: h[c] + pyr[c] <==> h[x] + pyr[x] R_2HBt2 subsystem: Transport, Extracellular R_2HBt2 equation: _2hb[e] + h[e] <==> 2hb[c] + h[c]
reactant: 479371
reactant: 479359
reactant: 479431
reactant: 479419
fast: false
is: ENSBTAG00000009483.2
product: 479455
product: 479552
product: 479515
product: 479491
reactant: 479443
product: 479527
product: 479479
reversible: true
reactant: 479407

479503
type: SpeciesReference
stoichiometry: 1.0
species: 462174

479383
type: SpeciesReference
stoichiometry: 6.0
species: 458806

479347
type: SpeciesReference
stoichiometry: 1.0
species: 447761

447761
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Acetone_C3H6O

479467
type: SpeciesReference
stoichiometry: 1.0
species: 447749

479539
type: SpeciesReference
stoichiometry: 6.0
species: 458794

479395
type: SpeciesReference
stoichiometry: 1.0
species: 462186

462186
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Lactate_C3H5O3

479371
type: SpeciesReference
stoichiometry: 1.0
species: 444479

444479
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: _2-Hydroxybutyrate_C4H7O3

479359
type: SpeciesReference
stoichiometry: 1.0
species: 447581

447581
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Acetoacetate_C4H5O3

479431
type: SpeciesReference
stoichiometry: 1.0
species: 467921

467921
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Pyruvate_C3H3O3

479419
type: SpeciesReference
stoichiometry: 1.0
species: 467909

479455
type: SpeciesReference
stoichiometry: 1.0
species: 444467

444467
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _2-Hydroxybutyrate_C4H7O3

479552
type: SpeciesReference
stoichiometry: 1.0
species: 467946

479515
type: SpeciesReference
stoichiometry: 1.0
species: 447569

447569
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Acetoacetate_C4H5O3

479491
type: SpeciesReference
stoichiometry: 1.0
species: 458879

458879
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: H+_H

479443
type: SpeciesReference
stoichiometry: 1.0
species: 458794

479527
type: SpeciesReference
stoichiometry: 1.0
species: 462138

462138
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Lactate_C3H5O3

479479
type: SpeciesReference
stoichiometry: 1.0
species: 467909

479407
type: SpeciesReference
stoichiometry: 1.0
species: 462150

462150
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: D-Lactate_C3H5O3

993542
type: Reaction
is: ENSBTAG00000000081.4
product: 529360
reversible: true
reactant: 529300
product: 529324
product: 529336
product: 529348
notes: R_CERT2rt subsystem: Transport, Endoplasmic Reticular R_CERT2rt equation: gluside_hs[c] <==> gluside_hs[r] R_CERT1gt subsystem: Transport, Golgi Apparatus R_CERT1gt equation: crm_hs[c] <==> crm_hs[g] R_CERT2gt subsystem: Transport, Golgi Apparatus R_CERT2gt equation: gluside_hs[c] <==> gluside_hs[g] R_CERT1rt subsystem: Transport, Endoplasmic Reticular R_CERT1rt equation: crm_hs[c] <==> crm_hs[r]
reactant: 529312
fast: false

529360
type: SpeciesReference
stoichiometry: 1.0
species: 457646

457646
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO

529300
type: SpeciesReference
stoichiometry: 2.0
species: 457610

457610
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO

529324
type: SpeciesReference
stoichiometry: 1.0
species: 451864

451864
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

529336
type: SpeciesReference
stoichiometry: 1.0
species: 457622

457622
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO

529348
type: SpeciesReference
stoichiometry: 1.0
species: 451840

451840
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

529312
type: SpeciesReference
stoichiometry: 2.0
species: 451828

452722
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: CTP_C9H12N3O14P3

447425
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Tyr-194 of apo-glycogenin protein (primer for glycogen synthesis)_XOH

992101
type: Reaction
reversible: false
fast: false
product: 517285
reactant: 517236
is: ENSBTAG00000003942.4
reactant: 517248
product: 517261
is: ENSBTAG00000018033.4
is: ENSBTAG00000006499.4
is: ENSBTAG00000031251.2
product: 517273
is: http://identifiers.org/ec-code/2.7.1.68
is: ENSBTAG00000002177.3
name: phosphatidylinositol 4-phosphate 5-kinase
notes: R_PI4P5K subsystem: Glycerophospholipid Metabolism R_PI4P5K equation: [c] : atp + pail4p_hs --> adp + h + pail45p_hs

517285
type: SpeciesReference
stoichiometry: 1.0
species: 458794

517236
type: SpeciesReference
stoichiometry: 1.0
species: 449983

517248
type: SpeciesReference
stoichiometry: 1.0
species: 466070

517261
type: SpeciesReference
stoichiometry: 1.0
species: 466046

517273
type: SpeciesReference
stoichiometry: 1.0
species: 448462

445553
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: _4-Aminobutanoate_C4H9NO2

989639
type: Reaction
is: http://identifiers.org/ec-code/1.14.11.2
product: 494037
reactant: 494001
product: 494061
name: L-Proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) (ER)
reversible: false
notes: R_PROAKGOX1r subsystem: Arginine and Proline Metabolism R_PROAKGOX1r equation: [r] : akg + o2 + pro-L --> 4hpro-LT + co2 + succ
product: 494049
is: ENSBTAG00000001116.4
is: ENSBTAG00000006045.4
reactant: 494013
fast: false
reactant: 494025
is: ENSBTAG00000032996.2

494037
type: SpeciesReference
stoichiometry: 1.0
species: 445709

445709
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: trans-4-Hydroxy-L-proline_C5H9NO3

494001
type: SpeciesReference
stoichiometry: 1.0
species: 465282

494061
type: SpeciesReference
stoichiometry: 1.0
species: 469202

469202
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Succinate_C4H4O4

494049
type: SpeciesReference
stoichiometry: 1.0
species: 451557

494013
type: SpeciesReference
stoichiometry: 1.0
species: 448982

448982
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _2-Oxoglutarate_C5H4O5

494025
type: SpeciesReference
stoichiometry: 1.0
species: 467461

467461
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: L-Proline_C5H9NO2

995760
type: Reaction
is: http://identifiers.org/ec-code/2.5.1.10
is: http://identifiers.org/ec-code/2.5.1.29
reactant: 551816
is: http://identifiers.org/ec-code/2.4.1.155
product: 551962
product: 551889
product: 551913
product: 551926
reactant: 551840
reversible: false
product: 551938
is: http://identifiers.org/ec-code/2.5.1.1
fast: false
notes: R_DMATT subsystem: Cholesterol Metabolism R_DMATT equation: [c] : dmpp + ipdp --> grdp + ppi R_FRTT subsystem: Cholesterol Metabolism R_FRTT equation: [c] : frdp + ipdp --> ggdp + ppi R_M16N6Tg subsystem: N-Glycan Biosynthesis R_M16N6Tg equation: [g] : n3m2masn + uacgam --> h + n4m2masn + udp R_GRTT subsystem: Cholesterol Metabolism R_GRTT equation: [c] : grdp + ipdp --> frdp + ppi
product: 551950
reactant: 551876
reactant: 551864
is: ENSBTAG00000013068.3
reactant: 551852
product: 551901
reactant: 551828

551816
type: SpeciesReference
stoichiometry: 1.0
species: 458263

458263
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Geranyl diphosphate_C10H17O7P2

551962
type: SpeciesReference
stoichiometry: 3.0
species: 467000

551889
type: SpeciesReference
stoichiometry: 1.0
species: 458263

551913
type: SpeciesReference
stoichiometry: 1.0
species: 470688

551926
type: SpeciesReference
stoichiometry: 1.0
species: 464446

464446
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: ((N-acetyl-D-glucosaminyl)4-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C66H109N6O45X

551840
type: SpeciesReference
stoichiometry: 1.0
species: 470652

551938
type: SpeciesReference
stoichiometry: 1.0
species: 458819

551950
type: SpeciesReference
stoichiometry: 1.0
species: 457308

457308
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Geranylgeranyl diphosphate_C20H33O7P2

551876
type: SpeciesReference
stoichiometry: 3.0
species: 460510

460510
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Isopentenyl diphosphate_C5H9O7P2

551864
type: SpeciesReference
stoichiometry: 1.0
species: 464410

464410
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: ((N-acetyl-D-glucosaminyl)3-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C58H96N5O40X

551852
type: SpeciesReference
stoichiometry: 1.0
species: 454270

454270
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Dimethylallyl diphosphate_C5H9O7P2

551901
type: SpeciesReference
stoichiometry: 1.0
species: 455968

455968
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Farnesyl diphosphate_C15H25O7P2

551828
type: SpeciesReference
stoichiometry: 1.0
species: 455968

460570
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: ITP_C10H11N4O14P3

461688
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate II (core 2-linked), degradation product 5_C50H82N4O38SX

450659
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Cob(I)alamin_C62H88CoN13O14P

462562
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: (R)-S-Lactoylglutathione_C13H20N3O8S

988130
type: Reaction
product: 479588
is: ENSBTAG00000011748.4
reversible: false
fast: false
reactant: 479564
product: 479600
name: Sphingomyelin synthase (homo sapiens)
notes: R_SMS subsystem: Sphingolipid Metabolism R_SMS equation: [c] : crm_hs + pchol_hs --> dag_hs + sphmyln_hs
reactant: 479576

479588
type: SpeciesReference
stoichiometry: 1.0
species: 452951

479564
type: SpeciesReference
stoichiometry: 1.0
species: 451828

479600
type: SpeciesReference
stoichiometry: 1.0
species: 468887

468887
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO

479576
type: SpeciesReference
stoichiometry: 1.0
species: 466238

466238
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

996121
type: Reaction
product: 556011
fast: false
notes: R_ILETA subsystem: Valine, Leucine, and Isoleucine Metabolism R_ILETA equation: [c] : akg + ile-L <==> 3mop + glu-L R_VALTA subsystem: Valine, Leucine, and Isoleucine Metabolism R_VALTA equation: [c] : akg + val-L <==> 3mob + glu-L R_LEUTA subsystem: Valine, Leucine, and Isoleucine Metabolism R_LEUTA equation: [c] : akg + leu-L <==> 4mop + glu-L
reactant: 555951
product: 556035
is: http://identifiers.org/ec-code/2.6.1.6
reactant: 555963
product: 556023
reactant: 555975
reactant: 555987
is: ENSBTAG00000013825.4
is: http://identifiers.org/ec-code/2.6.1.42
product: 555999
reversible: true

556011
type: SpeciesReference
stoichiometry: 1.0
species: 445179

445179
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: (S)-3-Methyl-2-oxopentanoate_C6H9O3

555951
type: SpeciesReference
stoichiometry: 3.0
species: 448946

556035
type: SpeciesReference
stoichiometry: 1.0
species: 445745

445745
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-Methyl-2-oxopentanoate_C6H9O3

555963
type: SpeciesReference
stoichiometry: 1.0
species: 471287

556023
type: SpeciesReference
stoichiometry: 3.0
species: 457525

555975
type: SpeciesReference
stoichiometry: 1.0
species: 460290

555987
type: SpeciesReference
stoichiometry: 1.0
species: 462319

555999
type: SpeciesReference
stoichiometry: 1.0
species: 445155

445155
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Methyl-2-oxobutanoate_C5H7O3

987589
type: Reaction
reactant: 474747
product: 474904
fast: false
product: 474892
product: 474856
is: http://identifiers.org/ec-code/1.3.3.6
reactant: 474832
reactant: 474784
product: 475025
reactant: 474844
reversible: false
reactant: 474796
product: 475073
reactant: 474760
reactant: 474820
product: 474976
product: 474880
reactant: 474808
reactant: 474772
reactant: 474650
reactant: 474711
reactant: 474662
product: 474952
is: ENSBTAG00000030174.2
reactant: 474723
reactant: 474613
reactant: 474675
product: 475013
reactant: 474637
product: 475049
product: 474988
product: 474916
reactant: 474687
product: 474964
product: 474868
is: http://identifiers.org/ec-code/1.3.99.3
product: 474940
reactant: 474699
reactant: 474735
reactant: 474625
product: 475000
product: 474928
product: 475061
product: 475037
notes: R_FAOXC2251836x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2251836x equation: [x] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_FAOXC180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC180x equation: [x] : coa + h2o + nad + o2 + stcoa --> accoa + h + h2o2 + nadh + pmtcoa R_FAOXC241181x subsystem: Fatty acid oxidation, peroxisome R_FAOXC241181x equation: [x] : (3) coa + (3) h2o + (3) nad + nrvnccoa + (3) o2 --> (3) accoa + (3) h + (3) h2o2 + (3) nadh + odecoa R_FAOXC2051843x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2051843x equation: [x] : coa + h2o + nad + tmndnccoa --> accoa + h + nadh + strdnccoa R_FAOXC2452253x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2452253x equation: [x] : coa + h2o + nad + o2 + tetpent3coa --> accoa + clpndcoa + h + h2o2 + nadh R_FAOXC2252053x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2252053x equation: [x] : coa + dcsptn1coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + tmndnccoa R_FAOXC183806x subsystem: Fatty acid oxidation, peroxisome R_FAOXC183806x equation: [x] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC200180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC200180x equation: [x] : arachcoa + coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + stcoa R_FAOXC16080x subsystem: Fatty acid oxidation, peroxisome R_FAOXC16080x equation: [x] : (4) coa + (4) h2o + (4) nad + (4) o2 + pmtcoa --> (4) accoa + (4) h + (4) h2o2 + (4) nadh + occoa R_FAOXC2242046x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2242046x equation: [x] : adrncoa + coa + h2o + nad + o2 --> accoa + arachdcoa + h + h2o2 + nadh R_FAOXC246226x subsystem: Fatty acid oxidation, peroxisome R_FAOXC246226x equation: [x] : coa + h2o + nad + o2 + tethex3coa --> accoa + c226coa + h + h2o2 + nadh R_ACOAO7p subsystem: Fatty Acid Metabolism R_ACOAO7p equation: [x] : o2 + pmtcoa --> h2o2 + hdd2coa R_FAOXC18480x subsystem: Fatty acid …

474747
type: SpeciesReference
stoichiometry: 1.0
species: 470204

470204
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: timnodonyl coenzyme A_C41H60N7O17P3S

474904
type: SpeciesReference
stoichiometry: 1.0
species: 453216

453216
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: docosa-4,7,10,13,16-pentaenoyl coenzyme A_C43H64N7O17P3S

474892
type: SpeciesReference
stoichiometry: 1.0
species: 469129

469129
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: stearidonyl coenzyme A_C39H58N7O17P3S

474856
type: SpeciesReference
stoichiometry: 1.0
species: 451350

451350
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: clupanodonyl CoA_C43H64N7O17P3S

474832
type: SpeciesReference
stoichiometry: 1.0
species: 459241

459241
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Hexacosanoyl-CoA (n-C26:0CoA)_C47H82N7O17P3S

474784
type: SpeciesReference
stoichiometry: 1.0
species: 469721

475025
type: SpeciesReference
stoichiometry: 1.0
species: 459145

459145
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695

474844
type: SpeciesReference
stoichiometry: 1.0
species: 469649

469649
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: tetracosapentaenoyl coenzyme A, n-6_C45H68N7O17P3S

474796
type: SpeciesReference
stoichiometry: 1.0
species: 450479

450479
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: cervonyl coenzyme A_C43H62N7O17P3S

475073
type: SpeciesReference
stoichiometry: 1.0
species: 449753

449753
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: C20:4-CoA_C41H62N7O17P3S

474760
type: SpeciesReference
stoichiometry: 32.0
species: 451671

474820
type: SpeciesReference
stoichiometry: 1.0
species: 448669

448669
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: adrenyl coenzyme A_C43H66N7O17P3S

474976
type: SpeciesReference
stoichiometry: 32.0
species: 458879

474880
type: SpeciesReference
stoichiometry: 1.0
species: 462514

462514
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: lignocericyl coenzyme A_C45H78N7O17P3S

474808
type: SpeciesReference
stoichiometry: 1.0
species: 462827

462827
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: gamma-linolenoyl-CoA_C39H60N7O17P3S

474772
type: SpeciesReference
stoichiometry: 1.0
species: 469032

469032
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S

474650
type: SpeciesReference
stoichiometry: 32.0
species: 458770

474711
type: SpeciesReference
stoichiometry: 2.0
species: 453216

474662
type: SpeciesReference
stoichiometry: 1.0
species: 469576

469576
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: tetracosapentaenoyl coenzyme A, n-3_C45H68N7O17P3S

474952
type: SpeciesReference
stoichiometry: 1.0
species: 449657

449657
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: arachidyl coenzyme A_C41H70N7O17P3S

474723
type: SpeciesReference
stoichiometry: 1.0
species: 469528

469528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: tetracosahexaenoyl coenzyme A_C45H66N7O17P3S

474613
type: SpeciesReference
stoichiometry: 2.0
species: 466856

466856
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S

474675
type: SpeciesReference
stoichiometry: 32.0
species: 464578

464578
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

475013
type: SpeciesReference
stoichiometry: 1.0
species: 450479

474637
type: SpeciesReference
stoichiometry: 1.0
species: 462514

475049
type: SpeciesReference
stoichiometry: 1.0
species: 448669

474988
type: SpeciesReference
stoichiometry: 1.0
species: 469032

474916
type: SpeciesReference
stoichiometry: 3.0
species: 465475

465475
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Octanoyl-CoA (n-C8:0CoA)_C29H46N7O17P3S

474687
type: SpeciesReference
stoichiometry: 1.0
species: 469129

474964
type: SpeciesReference
stoichiometry: 2.0
species: 470204

474868
type: SpeciesReference
stoichiometry: 1.0
species: 466856

474940
type: SpeciesReference
stoichiometry: 1.0
species: 465645

465645
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Octadecenoyl-CoA (n-C18:1CoA)_C39H64N7O17P3S

474699
type: SpeciesReference
stoichiometry: 22.0
species: 465294

474735
type: SpeciesReference
stoichiometry: 1.0
species: 449657

474625
type: SpeciesReference
stoichiometry: 1.0
species: 465174

465174
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: nervonyl coenzyme A_C45H76N7O17P3S

475000
type: SpeciesReference
stoichiometry: 1.0
species: 462827

474928
type: SpeciesReference
stoichiometry: 32.0
species: 464627

464627
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

475061
type: SpeciesReference
stoichiometry: 22.0
species: 458673

458673
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Hydrogen peroxide_H2O2

475037
type: SpeciesReference
stoichiometry: 32.0
species: 447725

992809
type: Reaction
modifier: 523661
is: http://identifiers.org/ec-code/1.2.1.1
reactant: 523529
fast: false
modifier: 523721
modifier: 523745
product: 523601
modifier: 523709
product: 523637
modifier: 523673
modifier: 523697
reactant: 523517
reactant: 523553
is: ENSBTAG00000006986.4
product: 523577
reversible: false
is: ENSBTAG00000016007.4
notes: R_ALCD22_D subsystem: Pyruvate Metabolism R_ALCD22_D equation: [c] : lald-D + nad --> h + mthgxl + nadh R_34DHOXPEGOX subsystem: Tyrosine metabolism R_34DHOXPEGOX equation: [c] : 34dhmald + h + nadh <==> 34dhoxpeg + nad R_ALCD1 subsystem: Miscellaneous R_ALCD1 equation: [c] : meoh + nad <==> fald + h + nadh R_ALCD2if subsystem: Glycolysis/Gluconeogenesis R_ALCD2if equation: [c] : etoh + nad --> acald + h + nadh R_ALCD21_D subsystem: Pyruvate Metabolism R_ALCD21_D equation: [c] : 12ppd-R + nad --> h + lald-D + nadh R_ALCD22_L subsystem: Pyruvate Metabolism R_ALCD22_L equation: [c] : lald-L + nad --> h + mthgxl + nadh R_LALDO subsystem: Pyruvate Metabolism R_LALDO equation: [c] : gthrd + lald-D + nad <==> h + lgt-S + nadh R_ALCD21_L subsystem: Pyruvate Metabolism R_ALCD21_L equation: [c] : 12ppd-S + nad --> h + lald-L + nadh R_FALDH subsystem: Tyrosine metabolism R_FALDH equation: [c] : fald + gthrd + nad <==> Sfglutth + h + nadh
is: http://identifiers.org/ec-code/1.2.1.49
modifier: 523733
product: 523589
modifier: 523757
modifier: 523769
modifier: 523685
product: 523625
reactant: 523565
modifier: 523649
reactant: 523505
reactant: 523541
is: http://identifiers.org/ec-code/1.1.1.78
is: http://identifiers.org/ec-code/1.1.1.1
product: 523613

444659
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3,4-Dihydroxyphenylethyleneglycol_C8H10O4

523529
type: SpeciesReference
stoichiometry: 1.0
species: 443985

443985
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: (R)-Propane-1,2-diol_C3H8O2

523601
type: SpeciesReference
stoichiometry: 1.0
species: 447617

447617
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Acetaldehyde_C2H4O

523637
type: SpeciesReference
stoichiometry: 5.0
species: 464590

463721
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Methanol_CH4O1

462550
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: (R)-S-Lactoylglutathione_C13H20N3O8S

523517
type: SpeciesReference
stoichiometry: 1.0
species: 462234

462234
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Lactaldehyde_C3H6O2

523553
type: SpeciesReference
stoichiometry: 1.0
species: 455472

455472
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Ethanol_C2H6O

523577
type: SpeciesReference
stoichiometry: 2.0
species: 464290

464290
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Methylglyoxal_C3H4O2

462210
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Lactaldehyde_C3H6O2

523589
type: SpeciesReference
stoichiometry: 1.0
species: 462234

444635
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3,4-Dihydroxymandelaldehyde_C8H8O4

523625
type: SpeciesReference
stoichiometry: 5.0
species: 458794

523565
type: SpeciesReference
stoichiometry: 1.0
species: 462210

523505
type: SpeciesReference
stoichiometry: 1.0
species: 443997

443997
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: (S)-Propane-1,2-diol_C3H8O2

523541
type: SpeciesReference
stoichiometry: 5.0
species: 464518

523613
type: SpeciesReference
stoichiometry: 1.0
species: 462210

448534
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: ADPglucose_C16H23N5O15P2

461528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 35_C241H384N17O205S11X

459253
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: hexacosanoyl carnitine_C33H65NO4

453348
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Dodecanoyl-ACP (n-C12:0ACP)_C23H43N2O8PRS

989651
type: Reaction
is: ENSBTAG00000018782.4
product: 494109
reactant: 494085
reactant: 494073
notes: R_3HKYNAKGAT subsystem: Tryptophan metabolism R_3HKYNAKGAT equation: [c] : akg + hLkynr --> 42A3HP24DB + glu-L R_KYNAKGAT subsystem: Tryptophan metabolism R_KYNAKGAT equation: [c] : Lkynr + akg --> 4aphdob + glu-L
product: 494121
reactant: 494097
is: http://identifiers.org/ec-code/2.6.1.7
is: ENSBTAG00000036099.2
product: 494133
is: ENSBTAG00000036101.2
fast: false
reversible: false

494109
type: SpeciesReference
stoichiometry: 1.0
species: 445589

445589
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-(2-Aminophenyl)-2,4-dioxobutanoate_C10H8NO4

494085
type: SpeciesReference
stoichiometry: 1.0
species: 458782

494073
type: SpeciesReference
stoichiometry: 2.0
species: 448946

494121
type: SpeciesReference
stoichiometry: 2.0
species: 457525

494097
type: SpeciesReference
stoichiometry: 1.0
species: 446913

446913
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Kynurenine_C10H12N2O3

494133
type: SpeciesReference
stoichiometry: 1.0
species: 445432

445432
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate_C10H8NO5

996639
type: Reaction
reactant: 560607
is: ENSBTAG00000000853.3
reversible: true
is: http://identifiers.org/ec-code/1.2.1.12
fast: false
product: 560633
name: glyceraldehyde-3-phosphate dehydrogenase
product: 560646
reactant: 560594
is: ENSBTAG00000032749.2
is: ENSBTAG00000015917.4
product: 560659
is: ENSBTAG00000018554.4
is: ENSBTAG00000021624.3
reactant: 560620
notes: R_GAPD subsystem: Glycolysis/Gluconeogenesis R_GAPD equation: [c] : g3p + nad + pi <==> 13dpg + h + nadh
is: ENSBTAG00000014731.4
is: ENSBTAG00000030368.2

560607
type: SpeciesReference
stoichiometry: 1.0
species: 464518

560633
type: SpeciesReference
stoichiometry: 1.0
species: 444057

560646
type: SpeciesReference
stoichiometry: 1.0
species: 458794

560594
type: SpeciesReference
stoichiometry: 1.0
species: 466736

560659
type: SpeciesReference
stoichiometry: 1.0
species: 464590

560620
type: SpeciesReference
stoichiometry: 1.0
species: 456540

456540
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Glyceraldehyde 3-phosphate_C3H5O6P

991813
type: Reaction
product: 512661
reactant: 512625
reactant: 512637
fast: false
is: http://identifiers.org/ec-code/3.1.3.57
notes: R_MI134PP subsystem: Inositol Phosphate Metabolism R_MI134PP equation: [c] : h2o + mi134p --> mi34p + pi R_MI14PP subsystem: Inositol Phosphate Metabolism R_MI14PP equation: [c] : h2o + mi14p --> mi4p-D + pi
product: 512673
product: 512649
is: ENSBTAG00000007584.3
reactant: 512613
reversible: false

512661
type: SpeciesReference
stoichiometry: 2.0
species: 466736

512625
type: SpeciesReference
stoichiometry: 2.0
species: 458685

512637
type: SpeciesReference
stoichiometry: 1.0
species: 464035

464035
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1D-myo-Inositol 1,4-bisphosphate_C6H10O12P2

512673
type: SpeciesReference
stoichiometry: 1.0
species: 464107

464107
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1D-myo-Inositol 4-phosphate_C6H11O9P

512649
type: SpeciesReference
stoichiometry: 1.0
species: 464083

464083
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1D-myo-Inositol 3,4-bisphosphate_C6H10O12P2

512613
type: SpeciesReference
stoichiometry: 1.0
species: 463987

463987
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1D-myo-Inositol 1,3,4-trisphosphate_C6H9O15P3

995436
type: Reaction
is: ENSBTAG00000014057.3
name: CMP-Sia Golgi transport via CMP antiport
product: 549138
reactant: 549102
product: 549126
notes: R_CMPACNAtg subsystem: Transport, Golgi Apparatus R_CMPACNAtg equation: cmp[g] + cmpacna[c] <==> cmp[c] + cmpacna[g]
fast: false
reactant: 549114
reversible: true

549138
type: SpeciesReference
stoichiometry: 1.0
species: 451471

549102
type: SpeciesReference
stoichiometry: 1.0
species: 451459

549126
type: SpeciesReference
stoichiometry: 1.0
species: 451398

549114
type: SpeciesReference
stoichiometry: 1.0
species: 451422

455497
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: F1alpha_C22H37N2O15X

461613
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 8_C115H186N8O88S2X

468935
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Sphingosine 1-phosphate_C18H37NO5P

994035
type: Reaction
is: ENSBTAG00000002995.4
notes: R_MAN1PT2 subsystem: Fructose and Mannose Metabolism R_MAN1PT2 equation: [c] : gdp + h + man1p --> gdpmann + pi
reactant: 534314
product: 534350
reactant: 534326
reversible: false
fast: false
is: ENSBTAG00000032026.1
is: http://identifiers.org/ec-code/2.7.7.22
reactant: 534302
name: mannose-1-phosphate guanylyltransferase (GDP)
product: 534338

534314
type: SpeciesReference
stoichiometry: 1.0
species: 463575

534350
type: SpeciesReference
stoichiometry: 1.0
species: 466736

534326
type: SpeciesReference
stoichiometry: 1.0
species: 458794

534302
type: SpeciesReference
stoichiometry: 1.0
species: 457199

534338
type: SpeciesReference
stoichiometry: 1.0
species: 457296

457296
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: GDP-D-mannose_C16H23N5O16P2

992821
type: Reaction
is: ENSBTAG00000019218.4
is: ENSBTAG00000004263.4
is: http://identifiers.org/ec-code/3.6.3.14
reactant: 523781
is: ENSBTAG00000021092.4
is: ENSBTAG00000013513.3
reactant: 523805
name: V-type ATPase, H+ transporting, lysosomal
fast: false
is: ENSBTAG00000014553.2
notes: R_ATPasel subsystem: Transport, Lysosomal R_ATPasel equation: atp[c] + (3) h[c] + h2o[c] --> adp[c] + (4) h[l] + pi[c]
is: ENSBTAG00000001927.4
is: ENSBTAG00000010620.4
product: 523830
is: ENSBTAG00000019890.2
is: ENSBTAG00000007572.3
reversible: false
is: ENSBTAG00000003450.3
is: ENSBTAG00000014491.3
is: ENSBTAG00000032551.2
is: ENSBTAG00000026428.3
is: ENSBTAG00000002703.3
is: ENSBTAG00000000292.4
product: 523817
is: ENSBTAG00000013734.2
is: ENSBTAG00000014238.3
is: ENSBTAG00000007272.3
is: ENSBTAG00000000203.3
product: 523842
reactant: 523793
is: ENSBTAG00000018889.3
is: ENSBTAG00000016309.4

523781
type: SpeciesReference
stoichiometry: 1.0
species: 449983

523805
type: SpeciesReference
stoichiometry: 3.0
species: 458794

523830
type: SpeciesReference
stoichiometry: 4.0
species: 458831

458831
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: H+_H

523817
type: SpeciesReference
stoichiometry: 1.0
species: 466736

523842
type: SpeciesReference
stoichiometry: 1.0
species: 448462

523793
type: SpeciesReference
stoichiometry: 1.0
species: 458685

443972
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _12 hydroxy arachidonic acid_C20H31O3

458468
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Reduced glutathione_C10H16N3O6S

444950
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695

453989
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: dIDP_C10H11N4O10P2

988730
type: Reaction
product: 485680
modifier: 485789
reactant: 485450
reactant: 485511
is: http://identifiers.org/ec-code/1.2.1.25
modifier: 485777
product: 485560
modifier: 485692
reversible: false
product: 485596
product: 485644
modifier: 485717
reactant: 485499
product: 485668
is: ENSBTAG00000001908.4
modifier: 485741
is: http://identifiers.org/ec-code/2.1.2.10
product: 485608
reactant: 485475
modifier: 485813
product: 485572
reactant: 485426
modifier: 485801
product: 485548
reactant: 485414
modifier: 485704
reactant: 485463
reactant: 485438
is: http://identifiers.org/ec-code/1.2.4.2
product: 485620
reactant: 485487
modifier: 485729
reactant: 485536
modifier: 485765
product: 485584
product: 485632
modifier: 485753
fast: false
notes: R_GCCbim subsystem: Glycine, Serine, and Threonine Metabolism R_GCCbim equation: [m] : alpro + thf --> dhlpro + mlthf + nh4 R_PDHm subsystem: Glycolysis/Gluconeogenesis R_PDHm equation: [m] : coa + nad + pyr --> accoa + co2 + nadh R_OIVD2m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD2m equation: [m] : 3mob + coa + nad --> co2 + ibcoa + nadh R_2OXOADOXm subsystem: Lysine Metabolism R_2OXOADOXm equation: [m] : 2oxoadp + coa + nad --> co2 + glutcoa + nadh R_GCCcm subsystem: Glycine, Serine, and Threonine Metabolism R_GCCcm equation: [m] : dhlpro + nad <==> h + lpro + nadh R_GCC2bim subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2bim equation: [m] : alpam + thf --> dhlam + mlthf + nh4 R_OIVD3m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD3m equation: [m] : 3mop + coa + nad --> 2mbcoa + co2 + nadh R_GCCam subsystem: Glycine, Serine, and Threonine Metabolism R_GCCam equation: [m] : gly + h + lpro <==> alpro + co2 R_GCC2cm subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2cm equation: [m] : dhlam + nad <==> h + lpam + nadh R_OIVD1m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD1m equation: [m] : 4mop + coa + nad --> co2 + ivcoa + nadh R_GCC2am subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2am equation: [m] : gly + h + lpam <==> alpam + co2 R_AKGDm subsystem: Citric Acid Cycle R_AKGDm equation: [m] : akg + coa + nad --> co2 + nadh + succoa
reactant: 485523
is: http://identifiers.org/ec-code/1.8.1.4
product: 485656
is: http://identifiers.org/ec-code/1.4.4.2
is: http://identifiers.org/ec-code/1.2.4.1

485680
type: SpeciesReference
stoichiometry: 6.0
species: 464602

485450
type: SpeciesReference
stoichiometry: 1.0
species: 449212

449212
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: S-Aminomethyldihydrolipoylprotein_CH6NS2X

485511
type: SpeciesReference
stoichiometry: 1.0
species: 467934

467934
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Pyruvate_C3H3O3

449200
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: S-aminomethyldihydrolipoamide_C9H21N2OS2

485560
type: SpeciesReference
stoichiometry: 1.0
species: 460594

460594
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Isovaleryl-CoA_C26H40N7O17P3S

485596
type: SpeciesReference
stoichiometry: 1.0
species: 457658

457658
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Glutaryl-CoA_C26H37N7O19P3S

485644
type: SpeciesReference
stoichiometry: 1.0
species: 453916

453916
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Dihydrolipoamide_C8H17NOS2

451545
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: CO2_CO2

485499
type: SpeciesReference
stoichiometry: 2.0
species: 469915

485668
type: SpeciesReference
stoichiometry: 2.0
species: 464157

485608
type: SpeciesReference
stoichiometry: 1.0
species: 453928

485475
type: SpeciesReference
stoichiometry: 6.0
species: 451632

485572
type: SpeciesReference
stoichiometry: 1.0
species: 444527

485426
type: SpeciesReference
stoichiometry: 1.0
species: 445757

457743
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Glycine_C2H5NO2

485548
type: SpeciesReference
stoichiometry: 1.0
species: 469226

485414
type: SpeciesReference
stoichiometry: 1.0
species: 444587

485463
type: SpeciesReference
stoichiometry: 1.0
species: 445167

445167
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _3-Methyl-2-oxobutanoate_C5H7O3

485438
type: SpeciesReference
stoichiometry: 1.0
species: 449200

485620
type: SpeciesReference
stoichiometry: 2.0
species: 464858

485487
type: SpeciesReference
stoichiometry: 1.0
species: 448970

485536
type: SpeciesReference
stoichiometry: 6.0
species: 464542

462899
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Lipoylprotein_S2X

485584
type: SpeciesReference
stoichiometry: 6.0
species: 451545

485632
type: SpeciesReference
stoichiometry: 1.0
species: 447689

462863
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Lipoamide_C8H15NOS2

485523
type: SpeciesReference
stoichiometry: 1.0
species: 445191

445191
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: (S)-3-Methyl-2-oxopentanoate_C6H9O3

485656
type: SpeciesReference
stoichiometry: 1.0
species: 460145

460145
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Isobutyryl-CoA_C25H38N7O17P3S

990864
type: Reaction
product: 503741
reversible: false
is: ENSBTAG00000016375.3
reactant: 503705
reactant: 503645
product: 503754
fast: false
product: 503766
reactant: 503681
product: 503717
reactant: 503669
reactant: 503693
product: 503729
reactant: 503657
notes: R_FAH3 subsystem: CYP Metabolism R_FAH3 equation: [c] : h + hdca + nadph + o2 --> h2o + nadp + whhdca R_FAH1 subsystem: CYP Metabolism R_FAH1 equation: [c] : ddca + h + nadph + o2 --> h2o + nadp + whddca R_FAH2 subsystem: CYP Metabolism R_FAH2 equation: [c] : h + nadph + o2 + ttdca --> h2o + nadp + whttdca

503741
type: SpeciesReference
stoichiometry: 1.0
species: 471371

471371
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: omega hydroxy hexadecanoate (n-C16:0)_C16H31O3

503705
type: SpeciesReference
stoichiometry: 3.0
species: 464711

503645
type: SpeciesReference
stoichiometry: 1.0
species: 459013

503754
type: SpeciesReference
stoichiometry: 3.0
species: 464639

503766
type: SpeciesReference
stoichiometry: 3.0
species: 458685

503681
type: SpeciesReference
stoichiometry: 3.0
species: 465234

503717
type: SpeciesReference
stoichiometry: 1.0
species: 471396

503669
type: SpeciesReference
stoichiometry: 1.0
species: 453360

453360
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Dodecanoate (n-C12:0)_C12H23O2

503693
type: SpeciesReference
stoichiometry: 3.0
species: 458794

503729
type: SpeciesReference
stoichiometry: 1.0
species: 471359

471359
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: omega hydroxy dodecanoate (n-C12:0)_C12H23O3

503657
type: SpeciesReference
stoichiometry: 1.0
species: 470519

455582
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

446586
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: _6-Pyruvoyl-5,6,7,8-tetrahydropterin_C9H11N5O3

449585
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Adenosine 5'-phosphosulfate_C10H12N5O10PS

457440
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Glucuronate_C6H9O7

450164
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Bilirubin beta-diglucuronide_C45H50N4O18

444623
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3,4-Dihydroxy-trans-cinnamate_C9H7O4

461274
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 16_C157H253N11O124S4X

447497
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Arabinitol_C5H12O5

996663
type: Reaction
product: 560806
product: 560782
fast: false
is: ENSBTAG00000016649.4
product: 560769
reactant: 560757
notes: R_P45011A1m subsystem: Steroid Metabolism R_P45011A1m equation: [m] : chsterol + h + nadph + (2) o2 --> 4mptnl + (2) h2o + nadp + prgnlone
product: 560794
is: http://identifiers.org/ec-code/1.14.15.6
reactant: 560745
reactant: 560721
name: Cytochrome P450 11A1, mitochondrial [Precursor]
reversible: false
reactant: 560733

560806
type: SpeciesReference
stoichiometry: 1.0
species: 464663

560782
type: SpeciesReference
stoichiometry: 1.0
species: 467219

467219
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Pregnenolone_C21H32O2

560769
type: SpeciesReference
stoichiometry: 2.0
species: 458733

560757
type: SpeciesReference
stoichiometry: 1.0
species: 458843

560794
type: SpeciesReference
stoichiometry: 1.0
species: 445769

445769
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _4-Methylpentanal_C6H12O

560745
type: SpeciesReference
stoichiometry: 2.0
species: 465258

560721
type: SpeciesReference
stoichiometry: 1.0
species: 451144

451144
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Cholesterol_C27H46O

560733
type: SpeciesReference
stoichiometry: 1.0
species: 464723

455136
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Elaidic carnitine_C25H47NO4

468731
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Sulfite_O3S

465027
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Methylputrescine_C5H16N2

992377
type: Reaction
product: 519229
reactant: 519217
notes: R_MMMm subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMMm equation: [m] : mmcoa-R <==> succoa
is: ENSBTAG00000014272.3
is: http://identifiers.org/ec-code/5.4.99.2
fast: false
reversible: true
name: methylmalonyl-CoA mutase

519229
type: SpeciesReference
stoichiometry: 1.0
species: 469226

519217
type: SpeciesReference
stoichiometry: 1.0
species: 464181

464181
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: (R)-Methylmalonyl-CoA_C25H35N7O19P3S

448909
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1-alkyl 2-lysoglycerol 3-phosphocholine_C10H21O5NPFULLR

469056
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: stearoylcarnitine_C25H49NO4

994619
type: Reaction
reactant: 541300
product: 541385
product: 541361
fast: false
is: ENSBTAG00000018883.4
product: 541325
is: http://identifiers.org/ec-code/2.7.1.30
reactant: 541288
product: 541373
notes: R_GLYKm subsystem: Glycerophospholipid Metabolism R_GLYKm equation: [m] : atp + glyc --> adp + glyc3p + h R_GLYK subsystem: Glycerophospholipid Metabolism R_GLYK equation: [c] : atp + glyc --> adp + glyc3p + h
product: 541349
product: 541337
is: ENSBTAG00000000301.3
is: ENSBTAG00000010624.4
reactant: 541276
is: ENSBTAG00000008124.4
reactant: 541312
reversible: false

541300
type: SpeciesReference
stoichiometry: 1.0
species: 450007

541385
type: SpeciesReference
stoichiometry: 1.0
species: 458843

541361
type: SpeciesReference
stoichiometry: 1.0
species: 457804

541325
type: SpeciesReference
stoichiometry: 1.0
species: 457816

541288
type: SpeciesReference
stoichiometry: 1.0
species: 457876

457876
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Glycerol_C3H8O3

541373
type: SpeciesReference
stoichiometry: 1.0
species: 458794

541349
type: SpeciesReference
stoichiometry: 1.0
species: 448462

541337
type: SpeciesReference
stoichiometry: 1.0
species: 448486

541276
type: SpeciesReference
stoichiometry: 1.0
species: 449983

541312
type: SpeciesReference
stoichiometry: 1.0
species: 457852

450383
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Biotin_C10H15N2O3S

989246
type: Reaction
is: ENSBTAG00000013208.2
reversible: false
name: ADP/ATP transporter, mitochondrial
product: 490348
notes: R_ATPtm subsystem: Transport, Mitochondrial R_ATPtm equation: adp[c] + atp[m] --> adp[m] + atp[c]
reactant: 490312
reactant: 490324
fast: false
product: 490336

490348
type: SpeciesReference
stoichiometry: 1.0
species: 448486

490312
type: SpeciesReference
stoichiometry: 1.0
species: 448462

490324
type: SpeciesReference
stoichiometry: 1.0
species: 450007

490336
type: SpeciesReference
stoichiometry: 1.0
species: 449983

455412
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Electron transfer flavoprotein oxidized_R

443900
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _11-Deoxycortisol_C21H30O4

451035
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622

446985
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Protein N6,N6,N6-trimethyl-L-lysine_C3H10X

459709
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: heparan sulfate, degradation product 24_C31H50NO26

996397
type: Reaction
reactant: 558255
product: 558304
reactant: 558231
reversible: true
reactant: 558206
reactant: 558267
reactant: 558243
reactant: 558219
product: 558340
reactant: 558280
product: 558328
reactant: 558292
product: 558316
product: 558388
product: 558364
is: ENSBTAG00000000839.4
product: 558352
notes: R_GSNtl subsystem: Transport, Lysosomal R_GSNtl equation: gsn[l] <==> gsn[c] R_ADEtl subsystem: Transport, Lysosomal R_ADEtl equation: ade[l] <==> ade[c] R_INStl subsystem: Transport, Lysosomal R_INStl equation: ins[l] <==> ins[c] R_Uritl subsystem: Transport, Lysosomal R_Uritl equation: uri[l] <==> uri[c] R_THYMDtl subsystem: Transport, Lysosomal R_THYMDtl equation: thymd[l] <==> thymd[c] R_HXANtl subsystem: Transport, Lysosomal R_HXANtl equation: hxan[l] <==> hxan[c] R_CYTDtl subsystem: Transport, Lysosomal R_CYTDtl equation: cytd[l] <==> cytd[c] R_ADNtl subsystem: Transport, Lysosomal R_ADNtl equation: adn[l] <==> adn[c]
fast: false
product: 558376

558255
type: SpeciesReference
stoichiometry: 1.0
species: 448426

448426
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Adenosine_C10H13N5O4

558304
type: SpeciesReference
stoichiometry: 1.0
species: 460047

558231
type: SpeciesReference
stoichiometry: 1.0
species: 452843

452843
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Cytidine_C9H13N3O5

558206
type: SpeciesReference
stoichiometry: 1.0
species: 460071

460071
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Hypoxanthine_C5H4N4O

558267
type: SpeciesReference
stoichiometry: 1.0
species: 448366

448366
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Adenine_C5H5N5

558243
type: SpeciesReference
stoichiometry: 1.0
species: 458311

458311
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Guanosine_C10H13N5O5

558219
type: SpeciesReference
stoichiometry: 1.0
species: 471143

471143
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Uridine_C9H12N2O6

558340
type: SpeciesReference
stoichiometry: 1.0
species: 448341

558280
type: SpeciesReference
stoichiometry: 1.0
species: 470095

470095
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Thymidine_C10H14N2O5

558328
type: SpeciesReference
stoichiometry: 1.0
species: 470071

558292
type: SpeciesReference
stoichiometry: 1.0
species: 460474

558316
type: SpeciesReference
stoichiometry: 1.0
species: 452819

558388
type: SpeciesReference
stoichiometry: 1.0
species: 471119

558364
type: SpeciesReference
stoichiometry: 1.0
species: 448402

558352
type: SpeciesReference
stoichiometry: 1.0
species: 458287

558376
type: SpeciesReference
stoichiometry: 1.0
species: 460449

465112
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Sulfate derivative of norepinephrine_C8H11NO6S

455546
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Fructose 6-phosphate_C6H11O9P

448052
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: N-Acetyl-L-glutamate_C7H9NO5

449899
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Asparagine_C4H8N2O3

469141
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: stearidonyl carnitine_C25H41NO4

997783
type: Reaction
reactant: 572226
product: 572286
reactant: 572238
product: 572262
is: ENSBTAG00000004510.4
name: Sarcosine dehydrogenase (m)
notes: R_SARDHm subsystem: Urea cycle/amino group metabolism R_SARDHm equation: [m] : fad + sarcs + thf --> fadh2 + gly + mlthf
product: 572274
reversible: false
reactant: 572250
fast: false
is: http://identifiers.org/ec-code/1.5.99.1

572226
type: SpeciesReference
stoichiometry: 1.0
species: 468419

468419
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Sarcosine_C3H7NO2

572286
type: SpeciesReference
stoichiometry: 1.0
species: 464157

572238
type: SpeciesReference
stoichiometry: 1.0
species: 469915

572262
type: SpeciesReference
stoichiometry: 1.0
species: 455618

572274
type: SpeciesReference
stoichiometry: 1.0
species: 457743

572250
type: SpeciesReference
stoichiometry: 1.0
species: 455570

451581
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Carbon monoxide_CO

465876
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

989435
type: Reaction
is: http://identifiers.org/ec-code/2.4.1.80
product: 491947
is: ENSBTAG00000016073.4
product: 491934
reversible: false
reactant: 491922
product: 491959
reactant: 491910
name: Ceramide glucosyltransferase
fast: false
notes: R_UGCG subsystem: Sphingolipid Metabolism R_UGCG equation: [r] : crm_hs + udpg --> gluside_hs + h + udp

491947
type: SpeciesReference
stoichiometry: 1.0
species: 458867

491934
type: SpeciesReference
stoichiometry: 1.0
species: 470738

470738
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: UDP_C9H11N2O12P2

491922
type: SpeciesReference
stoichiometry: 1.0
species: 451864

491959
type: SpeciesReference
stoichiometry: 1.0
species: 457646

491910
type: SpeciesReference
stoichiometry: 1.0
species: 470824

470824
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: UDPglucose_C15H22N2O17P2

992905
type: Reaction
is: ENSBTAG00000013980.3
reactant: 524365
fast: false
reactant: 524353
reversible: false
name: superoxide dismutase, extracellular
product: 524377
is: http://identifiers.org/ec-code/1.15.1.1
product: 524389
notes: R_SPODMe subsystem: ROS Detoxification R_SPODMe equation: [e] : (2) h + (2) o2s --> h2o2 + o2

524365
type: SpeciesReference
stoichiometry: 2.0
species: 465319

465319
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Superoxide anion_O2

524353
type: SpeciesReference
stoichiometry: 2.0
species: 458806

524377
type: SpeciesReference
stoichiometry: 1.0
species: 465246

465246
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: O2_O2

524389
type: SpeciesReference
stoichiometry: 1.0
species: 458625

458625
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Hydrogen peroxide_H2O2

451120
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Cholesterol_C27H46O

446658
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: heptaglutamyl folate (DHF)_C49H55N13O24

465415
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: _9-O-Acetylated GD3 (homo sapiens)_C54H90N3O29FULLRCO

992521
type: Reaction
product: 520083
product: 520107
reactant: 520047
reactant: 520071
reversible: true
reactant: 520059
product: 520095
notes: R_GLYBt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_GLYBt4_LPAREN_2_RPAREN_r equation: glyb[e] + (2) na1[e] <==> glyb[c] + (2) na1[c] R_ABUTt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_ABUTt4_LPAREN_2_RPAREN_r equation: _4abut[e] + (2) na1[e] <==> 4abut[c] + (2) na1[c]
fast: false
is: ENSBTAG00000038415.1

520083
type: SpeciesReference
stoichiometry: 1.0
species: 445528

445528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-Aminobutanoate_C4H9NO2

520107
type: SpeciesReference
stoichiometry: 1.0
species: 457779

457779
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Glycine betaine_C5H11NO2

520047
type: SpeciesReference
stoichiometry: 4.0
species: 464470

520071
type: SpeciesReference
stoichiometry: 1.0
species: 457792

457792
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Glycine betaine_C5H11NO2

520059
type: SpeciesReference
stoichiometry: 1.0
species: 445540

445540
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: _4-Aminobutanoate_C4H9NO2

520095
type: SpeciesReference
stoichiometry: 4.0
species: 464458

450455
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: cervonyl coenzyme A_C43H62N7O17P3S

466310
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Procollagen L-lysine_C7H14N3O2R2

460486
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Inosine_C10H12N4O5

990948
type: Reaction
product: 505144
is: ENSBTAG00000013635.2
fast: false
notes: R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h
is: ENSBTAG00000019480.2
is: ENSBTAG00000012945.4
product: 505156
is: ENSBTAG00000000445.4
is: ENSBTAG00000017480.4
reactant: 505120
reversible: false
is: http://identifiers.org/ec-code/3.1.4.17
name: _3',5'-cyclic-nucleotide phosphodiesterase
is: ENSBTAG00000000354.1
reactant: 505132

505144
type: SpeciesReference
stoichiometry: 1.0
species: 458070

458070
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: GMP_C10H12N5O8P

505156
type: SpeciesReference
stoichiometry: 1.0
species: 458794

505120
type: SpeciesReference
stoichiometry: 1.0
species: 444744

444744
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3',5'-Cyclic GMP_C10H11N5O7P

505132
type: SpeciesReference
stoichiometry: 1.0
species: 458685

990564
type: Reaction
is: ENSBTAG00000020449.4
notes: R_ETF subsystem: Fatty acid oxidation R_ETF equation: [m] : etfox + fadh2 --> etfrd + fad
reversible: false
fast: false
name: electron transfer flavoprotein
reactant: 501240
product: 501264
is: ENSBTAG00000012490.3
product: 501276
reactant: 501252

501240
type: SpeciesReference
stoichiometry: 1.0
species: 455412

501264
type: SpeciesReference
stoichiometry: 1.0
species: 455424

455424
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Electron transfer flavoprotein reduced_RH2

501276
type: SpeciesReference
stoichiometry: 1.0
species: 455570

501252
type: SpeciesReference
stoichiometry: 1.0
species: 455618

444671
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3,4-Dihydroxyphenylacetaldehyde_C8H8O3

470471
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Thiosulfate_O3S2

996373
type: Reaction
notes: R_TALA subsystem: Pentose Phosphate Pathway R_TALA equation: [c] : g3p + s7p <==> e4p + f6p
reversible: true
reactant: 558122
is: http://identifiers.org/ec-code/2.2.1.2
name: transaldolase
fast: false
product: 558146
is: ENSBTAG00000010336.3
reactant: 558110
product: 558134

558122
type: SpeciesReference
stoichiometry: 1.0
species: 456540

558146
type: SpeciesReference
stoichiometry: 1.0
species: 454968

558110
type: SpeciesReference
stoichiometry: 1.0
species: 468358

558134
type: SpeciesReference
stoichiometry: 1.0
species: 455546

995808
type: Reaction
notes: R_PPAP subsystem: Triacylglycerol Synthesis R_PPAP equation: [c] : h2o + pa_hs --> dag_hs + pi
product: 552218
name: phosphatidic acid phosphatase
reactant: 552194
is: ENSBTAG00000011640.4
product: 552230
is: ENSBTAG00000000717.3
reactant: 552206
is: http://identifiers.org/ec-code/3.1.3.4
is: ENSBTAG00000010526.4
reversible: false
fast: false

552218
type: SpeciesReference
stoichiometry: 1.0
species: 452951

552194
type: SpeciesReference
stoichiometry: 1.0
species: 465840

465840
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

552230
type: SpeciesReference
stoichiometry: 1.0
species: 466736

552206
type: SpeciesReference
stoichiometry: 1.0
species: 458685

997510
type: Reaction
name: xylulose reductase
reactant: 569829
reactant: 569841
is: ENSBTAG00000008747.4
reversible: true
notes: R_XYLUR subsystem: Pentose and Glucuronate Interconversions R_XYLUR equation: [c] : h + nadph + xylu-L <==> nadp + xylt
product: 569877
reactant: 569853
product: 569865
is: http://identifiers.org/ec-code/1.1.1.10
fast: false

569829
type: SpeciesReference
stoichiometry: 1.0
species: 471854

471854
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Xylulose_C5H10O5

569841
type: SpeciesReference
stoichiometry: 1.0
species: 458794

569877
type: SpeciesReference
stoichiometry: 1.0
species: 471830

471830
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Xylitol_C5H12O5

569853
type: SpeciesReference
stoichiometry: 1.0
species: 464711

569865
type: SpeciesReference
stoichiometry: 1.0
species: 464639

470336
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Triiodothyronine_C15H12I3NO4

994643
type: Reaction
reversible: false
product: 541592
product: 541556
product: 541544
notes: R_UDPGP subsystem: Starch and Sucrose Metabolism R_UDPGP equation: [c] : h2o + udpg --> g1p + (2) h + ump R_NNAT subsystem: NAD Metabolism R_NNAT equation: [c] : atp + h + nicrnt --> dnad + ppi R_DNADDP subsystem: NAD Metabolism R_DNADDP equation: [c] : dnad + h2o --> amp + (2) h + nicrnt
is: ENSBTAG00000020196.4
product: 541568
reactant: 541457
reactant: 541469
reactant: 541495
fast: false
is: http://identifiers.org/ec-code/2.7.7.18
reactant: 541482
product: 541531
product: 541604
reactant: 541507
reactant: 541519
is: ENSBTAG00000013165.4
is: http://identifiers.org/ec-code/3.6.1.9
product: 541580

541592
type: SpeciesReference
stoichiometry: 1.0
species: 454318

541556
type: SpeciesReference
stoichiometry: 1.0
species: 456451

541544
type: SpeciesReference
stoichiometry: 1.0
species: 470936

541568
type: SpeciesReference
stoichiometry: 1.0
species: 449296

541457
type: SpeciesReference
stoichiometry: 1.0
species: 464918

464918
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Nicotinate D-ribonucleotide_C11H12NO9P

541469
type: SpeciesReference
stoichiometry: 1.0
species: 470800

541495
type: SpeciesReference
stoichiometry: 2.0
species: 458685

541482
type: SpeciesReference
stoichiometry: 1.0
species: 449983

541531
type: SpeciesReference
stoichiometry: 1.0
species: 464918

541604
type: SpeciesReference
stoichiometry: 1.0
species: 467000

541507
type: SpeciesReference
stoichiometry: 1.0
species: 458794

541519
type: SpeciesReference
stoichiometry: 1.0
species: 454318

541580
type: SpeciesReference
stoichiometry: 4.0
species: 458794

988514
type: Reaction
reactant: 482753
is: ENSBTAG00000015399.4
is: ENSBTAG00000016752.3
reactant: 482729
notes: R_CAATPS subsystem: Transport, Extracellular R_CAATPS equation: atp[c] + (2) ca2[c] + h2o[c] --> adp[c] + (2) ca2[e] + h[e] + pi[c]
is: ENSBTAG00000037491.1
is: ENSBTAG00000022658.2
product: 482789
reversible: false
fast: false
product: 482777
is: ENSBTAG00000011797.4
is: ENSBTAG00000017012.4
is: ENSBTAG00000038799.1
is: ENSBTAG00000038950.1
is: ENSBTAG00000003275.4
is: ENSBTAG00000023954.3
is: ENSBTAG00000039432.1
is: http://identifiers.org/ec-code/3.6.3.6
reactant: 482741
product: 482801
is: ENSBTAG00000000517.4
is: ENSBTAG00000000520.4
product: 482765
is: ENSBTAG00000022931.3
is: ENSBTAG00000037762.1
is: ENSBTAG00000034472.2
is: ENSBTAG00000002392.4
is: ENSBTAG00000009043.4
is: ENSBTAG00000040222.1
is: ENSBTAG00000039055.1
is: ENSBTAG00000009552.4
is: ENSBTAG00000001305.4
name: Ca ATPase
is: ENSBTAG00000039071.1
is: ENSBTAG00000022922.3
is: ENSBTAG00000035765.2

482753
type: SpeciesReference
stoichiometry: 1.0
species: 449983

482729
type: SpeciesReference
stoichiometry: 2.0
species: 450539

450539
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Calcium_Ca

482789
type: SpeciesReference
stoichiometry: 1.0
species: 458806

482777
type: SpeciesReference
stoichiometry: 2.0
species: 450551

450551
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Calcium_Ca

482741
type: SpeciesReference
stoichiometry: 1.0
species: 458685

482801
type: SpeciesReference
stoichiometry: 1.0
species: 466736

482765
type: SpeciesReference
stoichiometry: 1.0
species: 448462

471733
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Xyl-L-Ser (protein)_C5H9O4X

456233
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)2 (Cer)1_C84H145N4O50FULLRCO

995232
type: Reaction
reversible: false
is: http://identifiers.org/ec-code/1.14.17.1
is: ENSBTAG00000004508.4
fast: false
product: 547460
is: ENSBTAG00000006363.4
reactant: 547436
reactant: 547424
name: dopamine beta-monooxygenase
is: ENSBTAG00000019460.4
notes: R_DOPABMO subsystem: Tyrosine metabolism R_DOPABMO equation: [c] : ascb-L + dopa + o2 --> dhdascb + h2o + nrpphr
product: 547484
product: 547472
reactant: 547448

547460
type: SpeciesReference
stoichiometry: 1.0
species: 465087

547436
type: SpeciesReference
stoichiometry: 1.0
species: 465234

547424
type: SpeciesReference
stoichiometry: 1.0
species: 454523

547484
type: SpeciesReference
stoichiometry: 1.0
species: 458685

547472
type: SpeciesReference
stoichiometry: 1.0
species: 453784

547448
type: SpeciesReference
stoichiometry: 1.0
species: 449850

464809
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Nicotinamide_C6H6N2O

993013
type: Reaction
product: 525295
reactant: 525283
is: ENSBTAG00000012113.4
reversible: false
fast: false
name: Nicotinamide N-methyltransferase
product: 525307
notes: R_NNMT subsystem: NAD Metabolism R_NNMT equation: [c] : amet + ncam --> 1mncam + ahcys
is: http://identifiers.org/ec-code/2.1.1.1
reactant: 525271

525295
type: SpeciesReference
stoichiometry: 1.0
species: 448813

525283
type: SpeciesReference
stoichiometry: 1.0
species: 464797

464797
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Nicotinamide_C6H6N2O

525307
type: SpeciesReference
stoichiometry: 1.0
species: 444177

444177
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1-Methylnicotinamide_C7H9N2O

525271
type: SpeciesReference
stoichiometry: 1.0
species: 449236

453482
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dGDP_C10H12N5O10P2

992149
type: Reaction
reactant: 517575
reactant: 517551
product: 517659
product: 517647
reactant: 517611
reversible: false
notes: R_SACCD3m subsystem: Lysine Metabolism R_SACCD3m equation: [m] : akg + h + lys-L + nadph --> h2o + nadp + saccrp-L R_SACCD4m subsystem: Lysine Metabolism R_SACCD4m equation: [m] : h2o + nadp + saccrp-L --> L2aadp6sa + glu-L + h + nadph
product: 517671
is: ENSBTAG00000012128.4
product: 517695
product: 517635
product: 517683
product: 517623
reactant: 517587
fast: false
reactant: 517563
is: http://identifiers.org/ec-code/1.5.1.8
reactant: 517599
is: http://identifiers.org/ec-code/1.5.1.10
reactant: 517539

517575
type: SpeciesReference
stoichiometry: 1.0
species: 448970

517551
type: SpeciesReference
stoichiometry: 1.0
species: 468394

468394
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Saccharopine_C11H19N2O6

517659
type: SpeciesReference
stoichiometry: 1.0
species: 457562

517647
type: SpeciesReference
stoichiometry: 1.0
species: 446804

446804
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-2-Aminoadipate 6-semialdehyde_C6H11NO3

517611
type: SpeciesReference
stoichiometry: 1.0
species: 458843

517671
type: SpeciesReference
stoichiometry: 1.0
species: 464663

517695
type: SpeciesReference
stoichiometry: 1.0
species: 458843

517635
type: SpeciesReference
stoichiometry: 1.0
species: 468394

517683
type: SpeciesReference
stoichiometry: 1.0
species: 464723

517623
type: SpeciesReference
stoichiometry: 1.0
species: 458733

517587
type: SpeciesReference
stoichiometry: 1.0
species: 464663

517563
type: SpeciesReference
stoichiometry: 1.0
species: 462959

462959
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Lysine_C6H15N2O2

517599
type: SpeciesReference
stoichiometry: 1.0
species: 464723

517539
type: SpeciesReference
stoichiometry: 1.0
species: 458733

452927
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: dADP_C10H12N5O9P2

444129
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _18 hydroxy arachidonic acid_C20H31O3

449417
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: androsterone glucuronide_C25H38O8

447033
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: R group 2 Coenzyme A homo sapiens_XCO2C21H31N7O15P3S

459181
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)_C27H49N2O8PRS

448016
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)3 (Glc)1 (GlcNAc)3 (Cer)1_C66H115N4O37FULLRCO

464145
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5,10-Methylenetetrahydrofolate_C20H21N7O6

461080
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 41_C34H58N2O26

994327
type: Reaction
product: 537789
reactant: 537764
reactant: 537740
is: ENSBTAG00000005218.4
is: ENSBTAG00000012100.4
is: ENSBTAG00000016396.4
notes: R_PDE1 subsystem: Nucleotides R_PDE1 equation: [c] : camp + h2o --> amp + h R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h
is: ENSBTAG00000017260.4
is: http://identifiers.org/ec-code/3.1.4.17
reversible: false
is: ENSBTAG00000008419.4
product: 537801
is: ENSBTAG00000004337.4
product: 537777
is: ENSBTAG00000002739.4
reactant: 537752
fast: false

537789
type: SpeciesReference
stoichiometry: 1.0
species: 449296

537764
type: SpeciesReference
stoichiometry: 2.0
species: 458685

537740
type: SpeciesReference
stoichiometry: 1.0
species: 450575

450575
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: cAMP_C10H11N5O6P

537801
type: SpeciesReference
stoichiometry: 2.0
species: 458794

537777
type: SpeciesReference
stoichiometry: 1.0
species: 458070

537752
type: SpeciesReference
stoichiometry: 1.0
species: 444744

989066
type: Reaction
product: 488721
reactant: 488697
fast: false
is: http://identifiers.org/ec-code/2.7.7.43
is: ENSBTAG00000010136.4
reactant: 488685
reversible: false
notes: R_CMPSASn subsystem: Aminosugar Metabolism R_CMPSASn equation: [n] : acnam + ctp --> cmpacna + ppi R_CMPSAS subsystem: Aminosugar Metabolism R_CMPSAS equation: [c] : acnam + ctp --> cmpacna + ppi
product: 488757
reactant: 488709
product: 488745
reactant: 488673
product: 488733

488721
type: SpeciesReference
stoichiometry: 1.0
species: 451459

488697
type: SpeciesReference
stoichiometry: 1.0
species: 448208

448208
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: N-Acetylneuraminate_C11H18NO9

488685
type: SpeciesReference
stoichiometry: 1.0
species: 448184

448184
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Acetylneuraminate_C11H18NO9

488757
type: SpeciesReference
stoichiometry: 1.0
species: 467000

488709
type: SpeciesReference
stoichiometry: 1.0
species: 452697

488745
type: SpeciesReference
stoichiometry: 1.0
species: 451483

451483
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: CMP-N-acetylneuraminate_C20H29N4O16P

488673
type: SpeciesReference
stoichiometry: 1.0
species: 452722

488733
type: SpeciesReference
stoichiometry: 1.0
species: 467024

457586
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: _5-L-Glutamyl-L-alanine_C8H13N2O5

993734
type: Reaction
is: ENSBTAG00000005614.4
product: 531051
fast: false
notes: R_UDPGLDCg subsystem: Nucleotide Sugar Metabolism R_UDPGLDCg equation: [g] : h + udpglcur --> co2 + udpxyl
reactant: 531026
product: 531039
reactant: 531014
name: UDP-D-glucuronate decarboxylase, Golgi apparatus
reversible: false
is: http://identifiers.org/ec-code/4.1.1.35

531051
type: SpeciesReference
stoichiometry: 1.0
species: 451532

451532
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: CO2_CO2

531026
type: SpeciesReference
stoichiometry: 1.0
species: 470872

470872
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: UDP-D-glucuronate_C15H19N2O18P2

531039
type: SpeciesReference
stoichiometry: 1.0
species: 470910

470910
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: UDP-D-xylose_C14H20N2O16P2

531014
type: SpeciesReference
stoichiometry: 1.0
species: 458819

460679
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 12_C174H279N12O153S9

453892
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: _7,8-Dihydrofolate_C19H19N7O6

995832
type: Reaction
reactant: 552399
notes: R_MM5bg subsystem: N-Glycan Biosynthesis R_MM5bg equation: [g] : h2o + m5masnB1 --> m4masn + man R_MM7Cbg subsystem: N-Glycan Biosynthesis R_MM7Cbg equation: [g] : h2o + m7masnC --> m6masnC + man R_MM6B2g subsystem: N-Glycan Biosynthesis R_MM6B2g equation: [g] : h2o + m6masnB2 --> m5masnB2 + man R_MM6bg subsystem: N-Glycan Biosynthesis R_MM6bg equation: [g] : h2o + m6masnC --> m5masnC + man R_MM8Ag subsystem: N-Glycan Biosynthesis R_MM8Ag equation: [g] : h2o + m8masn --> m7masnA + man R_MM8Cg subsystem: N-Glycan Biosynthesis R_MM8Cg equation: [g] : h2o + m8masn --> m7masnC + man R_MM7Cag subsystem: N-Glycan Biosynthesis R_MM7Cag equation: [g] : h2o + m7masnA --> m6masnC + man R_MM6B1ag subsystem: N-Glycan Biosynthesis R_MM6B1ag equation: [g] : h2o + m6masnB1 --> m5masnB1 + man R_MM7B2g subsystem: N-Glycan Biosynthesis R_MM7B2g equation: [g] : h2o + m7masnB --> m6masnB2 + man R_MM6B1bg subsystem: N-Glycan Biosynthesis R_MM6B1bg equation: [g] : h2o + m6masnB2 --> m5masnB1 + man R_MM5ag subsystem: N-Glycan Biosynthesis R_MM5ag equation: [g] : h2o + m5masnC --> m4masn + man R_MM5cg subsystem: N-Glycan Biosynthesis R_MM5cg equation: [g] : h2o + m5masnB2 --> m4masn + man R_MM7B1g subsystem: N-Glycan Biosynthesis R_MM7B1g equation: [g] : h2o + m7masnB --> m6masnB1 + man
reactant: 552326
product: 552473
product: 552461
product: 552485
product: 552534
product: 552510
product: 552497
reactant: 552338
reactant: 552363
reactant: 552424
product: 552546
fast: false
product: 552522
reactant: 552351
reactant: 552387
product: 552436
reactant: 552314
reversible: false
is: http://identifiers.org/ec-code/3.2.1.113
product: 552448
reactant: 552411
reactant: 552375
reactant: 552302
is: ENSBTAG00000003586.4

552399
type: SpeciesReference
stoichiometry: 2.0
species: 463201

552326
type: SpeciesReference
stoichiometry: 1.0
species: 463141

552473
type: SpeciesReference
stoichiometry: 1.0
species: 463286

552461
type: SpeciesReference
stoichiometry: 1.0
species: 463141

552485
type: SpeciesReference
stoichiometry: 1.0
species: 463189

552534
type: SpeciesReference
stoichiometry: 13.0
species: 463624

552510
type: SpeciesReference
stoichiometry: 1.0
species: 463249

552497
type: SpeciesReference
stoichiometry: 2.0
species: 463213

552338
type: SpeciesReference
stoichiometry: 1.0
species: 463286

552363
type: SpeciesReference
stoichiometry: 1.0
species: 463189

552424
type: SpeciesReference
stoichiometry: 1.0
species: 463117

552546
type: SpeciesReference
stoichiometry: 2.0
species: 463117

552522
type: SpeciesReference
stoichiometry: 1.0
species: 463201

552351
type: SpeciesReference
stoichiometry: 13.0
species: 458709

552387
type: SpeciesReference
stoichiometry: 1.0
species: 463249

552436
type: SpeciesReference
stoichiometry: 3.0
species: 463081

552314
type: SpeciesReference
stoichiometry: 1.0
species: 463129

552448
type: SpeciesReference
stoichiometry: 1.0
species: 463129

552411
type: SpeciesReference
stoichiometry: 2.0
species: 463322

552375
type: SpeciesReference
stoichiometry: 1.0
species: 463213

552302
type: SpeciesReference
stoichiometry: 2.0
species: 463261

471167
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Uridine_C9H12N2O6

460218
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Iduronate_C6H9O7

444539
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _2-Methyl-3-oxopropanoate_C4H5O3

460630
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: potassium_K

464230
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: beta-1,4-mannose-N-acetylglucosamine_C14H25NO11

468115
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _9-cis-retinol_C20H30O

455352
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: estrone glucuronide_C24H30O8

466820
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Phosphate_HO4P

988034
type: Reaction
product: 478761
reactant: 478688
product: 478737
product: 478724
notes: R_FATP3t subsystem: Transport, Extracellular R_FATP3t equation: na1[c] + ocdca[c] <==> na1[e] + ocdca[e] R_FATP1t subsystem: Transport, Extracellular R_FATP1t equation: hdca[c] + na1[c] <==> hdca[e] + na1[e] R_FATP2t subsystem: Transport, Extracellular R_FATP2t equation: na1[c] + ocdcea[c] <==> na1[e] + ocdcea[e]
reversible: true
reactant: 478676
product: 478749
is: ENSBTAG00000003533.4
reactant: 478700
is: ENSBTAG00000016775.4
fast: false
reactant: 478712

478761
type: SpeciesReference
stoichiometry: 1.0
species: 465511

465511
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: octadecanoate (n-C18:0)_C18H35O2

478688
type: SpeciesReference
stoichiometry: 1.0
species: 465499

478737
type: SpeciesReference
stoichiometry: 1.0
species: 459025

459025
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Hexadecanoate (n-C16:0)_C16H31O2

478724
type: SpeciesReference
stoichiometry: 1.0
species: 465535

465535
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: octadecenoate (n-C18:1)_C18H33O2

478676
type: SpeciesReference
stoichiometry: 1.0
species: 459013

478749
type: SpeciesReference
stoichiometry: 3.0
species: 464470

478700
type: SpeciesReference
stoichiometry: 1.0
species: 465523

478712
type: SpeciesReference
stoichiometry: 3.0
species: 464458

987961
type: Reaction
product: 478214
product: 478226
notes: R_S6T3g subsystem: Keratan sulfate biosynthesis R_S6T3g equation: [g] : ksii_core2_pre10 + paps --> h + ksii_core2 + pap R_S6T18g subsystem: Keratan sulfate biosynthesis R_S6T18g equation: [g] : ksii_core4_pre10 + paps --> h + ksii_core4 + pap R_S6T15g subsystem: Keratan sulfate biosynthesis R_S6T15g equation: [g] : ksi_pre36 + paps --> h + ksi + pap
fast: false
is: ENSBTAG00000003721.4
reactant: 478165
reversible: false
reactant: 478189
product: 478250
reactant: 478177
reactant: 478201
product: 478262
product: 478238

478214
type: SpeciesReference
stoichiometry: 1.0
species: 461177

461177
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I_C247H393N17O213S12X

478226
type: SpeciesReference
stoichiometry: 3.0
species: 466202

478165
type: SpeciesReference
stoichiometry: 1.0
species: 461968

461968
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 10_C89H143N7O69S2X

478189
type: SpeciesReference
stoichiometry: 3.0
species: 466226

478250
type: SpeciesReference
stoichiometry: 1.0
species: 461945

461945
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II (core 4-linked)_C89H142N7O72S3X

478177
type: SpeciesReference
stoichiometry: 1.0
species: 461540

461540
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 36_C247H394N17O210S11X

478201
type: SpeciesReference
stoichiometry: 1.0
species: 461775

461775
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 10_C81H130N6O64S2X

478262
type: SpeciesReference
stoichiometry: 3.0
species: 458819

478238
type: SpeciesReference
stoichiometry: 1.0
species: 461751

461751
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II (core 2-linked)_C81H129N6O67S3X

990336
type: Reaction
product: 499577
fast: false
reactant: 499541
reactant: 499565
reversible: false
product: 499602
is: ENSBTAG00000001868.3
reactant: 499529
reactant: 499553
is: http://identifiers.org/ec-code/2.7.7.14
product: 499589
notes: R_PETHCT subsystem: Glycerophospholipid Metabolism R_PETHCT equation: [c] : ctp + ethamp + h --> cdpea + ppi R_EPCTX subsystem: Glycerophospholipid Metabolism R_EPCTX equation: [c] : 2ameph + ctp + h --> cmp2amep + ppi

499577
type: SpeciesReference
stoichiometry: 1.0
species: 450805

450805
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: CDPethanolamine_C11H19N4O11P2

499541
type: SpeciesReference
stoichiometry: 1.0
species: 455448

499565
type: SpeciesReference
stoichiometry: 2.0
species: 452697

499602
type: SpeciesReference
stoichiometry: 2.0
species: 467000

499529
type: SpeciesReference
stoichiometry: 1.0
species: 444346

444346
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: (2-Aminoethyl)phosphonate_C2H7NO3P

499553
type: SpeciesReference
stoichiometry: 2.0
species: 458794

499589
type: SpeciesReference
stoichiometry: 1.0
species: 451386

451386
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610

466397
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2

991224
type: Reaction
product: 507357
reactant: 507345
notes: R_H2Otm subsystem: Transport, Mitochondrial R_H2Otm equation: h2o[c] <==> h2o[m]
is: ENSBTAG00000020184.4
fast: false
reversible: true
name: H2O transport, mitochondrial

507357
type: SpeciesReference
stoichiometry: 1.0
species: 458733

507345
type: SpeciesReference
stoichiometry: 1.0
species: 458685

994415
type: Reaction
product: 539066
reversible: false
is: ENSBTAG00000002454.4
reactant: 539006
product: 539054
product: 539042
reactant: 539030
fast: false
notes: R_G13MT_L subsystem: N-Glycan Biosynthesis R_G13MT_L equation: [c] : gdpmann + (0.1) mpdol_L --> gdp + h + (0.1) m1mpdol_L R_G13MT_U subsystem: N-Glycan Biosynthesis R_G13MT_U equation: [c] : gdpmann + (0.1) mpdol_U --> gdp + h + (0.1) m1mpdol_U
is: http://identifiers.org/ec-code/2.4.1.132
reactant: 539018
product: 539078

539066
type: SpeciesReference
stoichiometry: 2.0
species: 458794

539006
type: SpeciesReference
stoichiometry: 2.0
species: 457296

539054
type: SpeciesReference
stoichiometry: 1.0
species: 462983

462983
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: alpha-D-mannosyl-beta-D-mannosyl-diacylchitobiosyldiphosphodolichol, human liver homolog_C1360H2228N20O270P20

539042
type: SpeciesReference
stoichiometry: 2.0
species: 457199

539030
type: SpeciesReference
stoichiometry: 1.0
species: 464266

464266
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol, human uterine homolog_C1245H2040N20O220P20

539018
type: SpeciesReference
stoichiometry: 1.0
species: 464254

464254
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol, human liver homolog_C1300H2128N20O220P20

539078
type: SpeciesReference
stoichiometry: 1.0
species: 462995

462995
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: alpha-D-mannosyl-beta-D-mannosyl-diacylchitobiosyldiphosphodolichol, human uterine homolog_C1305H2140N20O270P20

471805
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Xylose_C5H10O5

449489
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: alpha-Pinene-oxide_C10H16O

463769
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Mercaptolactate_C3H5O3S

455328
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Estrone_C18H22O2

996193
type: Reaction
fast: false
reactant: 556678
notes: R_SR5ARr subsystem: Steroid Metabolism R_SR5ARr equation: [r] : h + nadph + tststerone --> 5adtststerone + nadp R_SR5AR2r subsystem: Steroid Metabolism R_SR5AR2r equation: [r] : andrstndn + h + nadph --> andrstandn + nadp
reactant: 556704
is: ENSBTAG00000015478.4
is: http://identifiers.org/ec-code/1.3.99.5
reversible: false
product: 556741
reactant: 556665
product: 556729
product: 556717
reactant: 556691

556678
type: SpeciesReference
stoichiometry: 1.0
species: 470409

470409
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Testosterone_C19H28O2

556704
type: SpeciesReference
stoichiometry: 2.0
species: 458867

556741
type: SpeciesReference
stoichiometry: 1.0
species: 445998

445998
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _5alpha-Dihydrotestosterone_C19H30O2

556665
type: SpeciesReference
stoichiometry: 2.0
species: 464747

556729
type: SpeciesReference
stoichiometry: 2.0
species: 464687

556717
type: SpeciesReference
stoichiometry: 1.0
species: 449381

556691
type: SpeciesReference
stoichiometry: 1.0
species: 449393

995076
type: Reaction
product: 546144
reactant: 546023
reactant: 546011
reactant: 546048
product: 546132
is: http://identifiers.org/ec-code/3.1.4.3
notes: R_PI4PLC subsystem: Inositol Phosphate Metabolism R_PI4PLC equation: [c] : h2o + pail4p_hs --> dag_hs + h + mi14p R_PI45PLC subsystem: Inositol Phosphate Metabolism R_PI45PLC equation: [c] : h2o + pail45p_hs --> dag_hs + h + mi145p R_PIPLC subsystem: Inositol Phosphate Metabolism R_PIPLC equation: [c] : h2o + pail_hs --> dag_hs + h + mi1p-D R_PI45PLCn subsystem: Inositol Phosphate Metabolism R_PI45PLCn equation: [n] : h2o + pail45p_hs --> dag_hs + h + mi145p R_PIPLCn subsystem: Inositol Phosphate Metabolism R_PIPLCn equation: [n] : h2o + pail_hs --> dag_hs + h + mi1p-D R_PI4PLCn subsystem: Inositol Phosphate Metabolism R_PI4PLCn equation: [n] : h2o + pail4p_hs --> dag_hs + h + mi14p
is: ENSBTAG00000008338.4
reactant: 545962
reactant: 545974
reactant: 545999
reactant: 545986
product: 546108
product: 546156
product: 546084
reversible: false
fast: false
product: 546060
product: 546072
product: 546120
is: http://identifiers.org/ec-code/3.1.4.11
product: 546096
product: 546168
reactant: 546036

546144
type: SpeciesReference
stoichiometry: 1.0
species: 464011

464011
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1D-myo-Inositol 1,4,5-trisphosphate_C6H9O15P3

546023
type: SpeciesReference
stoichiometry: 1.0
species: 466082

466082
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: _1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

546011
type: SpeciesReference
stoichiometry: 1.0
species: 466070

546048
type: SpeciesReference
stoichiometry: 3.0
species: 458746

546132
type: SpeciesReference
stoichiometry: 1.0
species: 464023

464023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: _1D-myo-Inositol 1,4,5-trisphosphate_C6H9O15P3

545962
type: SpeciesReference
stoichiometry: 1.0
species: 466058

466058
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: phosphatidylinositol 4,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

545974
type: SpeciesReference
stoichiometry: 1.0
species: 466142

466142
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: phosphatidylinositol (homo sapiens)_C9H16O9PFULLRCO2FULLR2CO2

545999
type: SpeciesReference
stoichiometry: 1.0
species: 466130

545986
type: SpeciesReference
stoichiometry: 1.0
species: 466046

546108
type: SpeciesReference
stoichiometry: 1.0
species: 464047

464047
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: _1D-myo-Inositol 1,4-bisphosphate_C6H10O12P2

546156
type: SpeciesReference
stoichiometry: 1.0
species: 464035

546084
type: SpeciesReference
stoichiometry: 3.0
species: 458855

546060
type: SpeciesReference
stoichiometry: 3.0
species: 452951

546072
type: SpeciesReference
stoichiometry: 1.0
species: 464059

464059
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1D-myo-Inositol 1-phosphate_C6H11O9P

546120
type: SpeciesReference
stoichiometry: 3.0
species: 452975

452975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2

546096
type: SpeciesReference
stoichiometry: 1.0
species: 464071

464071
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: _1D-myo-Inositol 1-phosphate_C6H11O9P

546168
type: SpeciesReference
stoichiometry: 3.0
species: 458794

546036
type: SpeciesReference
stoichiometry: 3.0
species: 458685

444719
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-(4-Hydroxyphenyl)pyruvate_C9H7O4

457985
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: glycogen, structure 5 (glycogenin-2[1,4-Glc])_C12H21O11X

454209
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _2,6 dimethylheptanoyl-CoA_C30H52N7O17P3S

991200
type: Reaction
product: 507247
name: _3-mercaptopyruvate sulfurtransferase
reactant: 507211
fast: false
is: http://identifiers.org/ec-code/2.8.1.2
product: 507259
reversible: false
product: 507235
is: ENSBTAG00000035939.1
notes: R_MCPST subsystem: Cysteine Metabolism R_MCPST equation: [c] : cyan + mercppyr --> h + pyr + tcynt
reactant: 507223
is: ENSBTAG00000030648.1
is: ENSBTAG00000035936.1

507247
type: SpeciesReference
stoichiometry: 1.0
species: 469419

469419
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Thiocyanate_CNS

507211
type: SpeciesReference
stoichiometry: 1.0
species: 452734

452734
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Hydrogen cyanide_CHN

507259
type: SpeciesReference
stoichiometry: 1.0
species: 458794

507235
type: SpeciesReference
stoichiometry: 1.0
species: 467909

507223
type: SpeciesReference
stoichiometry: 1.0
species: 463781

463781
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Mercaptopyruvate_C3H3O3S

471673
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _7-alpha,24(S)-Dihydroxycholesterol_C27H46O3

450287
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Biocytin_C16H28N4O4S

990360
type: Reaction
is: http://identifiers.org/ec-code/5.1.99.4
notes: R_AMACRr subsystem: Bile Acid Biosynthesis R_AMACRr equation: [r] : cholcoar --> cholcoas R_AMACRp subsystem: Bile Acid Biosynthesis R_AMACRp equation: [x] : cholcoar --> cholcoas R_AMACR2p subsystem: Bile Acid Biosynthesis R_AMACR2p equation: [x] : dhcholestancoa + (0.5) o2 --> dhcholoylcoa + h2o R_AMACR2r subsystem: Bile Acid Biosynthesis R_AMACR2r equation: [r] : dhcholestancoa + (0.5) o2 --> dhcholoylcoa + h2o
product: 499749
reactant: 499713
reactant: 499663
reactant: 499675
reversible: false
product: 499737
reactant: 499688
product: 499797
is: ENSBTAG00000021813.4
fast: false
reactant: 499725
product: 499785
reactant: 499701
product: 499773
product: 499761

499749
type: SpeciesReference
stoichiometry: 1.0
species: 453747

453747
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622

499713
type: SpeciesReference
stoichiometry: 1.0
species: 453735

499663
type: SpeciesReference
stoichiometry: 1.0
species: 451023

451023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695

499675
type: SpeciesReference
stoichiometry: 1.0
species: 465282

499737
type: SpeciesReference
stoichiometry: 1.0
species: 458770

499688
type: SpeciesReference
stoichiometry: 1.0
species: 465294

499797
type: SpeciesReference
stoichiometry: 1.0
species: 451035

499725
type: SpeciesReference
stoichiometry: 1.0
species: 451011

451011
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622

499785
type: SpeciesReference
stoichiometry: 1.0
species: 451047

451047
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695

499701
type: SpeciesReference
stoichiometry: 1.0
species: 453723

453723
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622

499773
type: SpeciesReference
stoichiometry: 1.0
species: 458758

499761
type: SpeciesReference
stoichiometry: 1.0
species: 453759

461455
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 2_C87H142N6O62X

471311
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Valine_C5H11NO2

449669
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: arachidyl carnitine_C27H53NO4

994716
type: Reaction
reactant: 542329
product: 542438
reversible: false
product: 542450
product: 542487
fast: false
reactant: 542353
reactant: 542341
product: 542402
reactant: 542365
is: ENSBTAG00000020006.3
notes: R_S23T4g subsystem: Keratan sulfate biosynthesis R_S23T4g equation: [g] : cmpacna + ksii_core4_pre1 --> cmp + h + ksii_core4_pre2 R_ST3GAL21g subsystem: Sphingolipid Metabolism R_ST3GAL21g equation: [g] : cmpacna + ga1_hs --> cmp + gm1b_hs + h R_ST3GAL22g subsystem: Sphingolipid Metabolism R_ST3GAL22g equation: [g] : cmpacna + gm1_hs --> cmp + gd1a_hs + h R_SIAT4Bg subsystem: Sphingolipid Metabolism R_SIAT4Bg equation: [g] : cmpacna + galgbside_hs --> acngalgbside_hs + cmp + h R_S23T2g subsystem: Keratan sulfate biosynthesis R_S23T2g equation: [g] : cmpacna + core2 --> cmp + h + ksii_core2_pre1 R_ST3GAL23g subsystem: Sphingolipid Metabolism R_ST3GAL23g equation: [g] : cmpacna + gd1b_hs --> cmp + gt1b_hs + h
product: 542426
is: http://identifiers.org/ec-code/2.4.99.4
product: 542475
product: 542414
reactant: 542317
reactant: 542390
reactant: 542378
product: 542463

542329
type: SpeciesReference
stoichiometry: 1.0
species: 457997

542438
type: SpeciesReference
stoichiometry: 1.0
species: 458021

542450
type: SpeciesReference
stoichiometry: 1.0
species: 461787

461787
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 1_C33H53N3O23X

542487
type: SpeciesReference
stoichiometry: 1.0
species: 458360

542353
type: SpeciesReference
stoichiometry: 1.0
species: 461982

461982
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 1_C36H60N3O25X

542341
type: SpeciesReference
stoichiometry: 6.0
species: 451471

542402
type: SpeciesReference
stoichiometry: 1.0
species: 457091

542365
type: SpeciesReference
stoichiometry: 1.0
species: 456592

542426
type: SpeciesReference
stoichiometry: 1.0
species: 448268

448268
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: sialyl galactosylgloboside (homo sapiens)_C61H105N3O35FULLRCO

542475
type: SpeciesReference
stoichiometry: 6.0
species: 451422

542414
type: SpeciesReference
stoichiometry: 6.0
species: 458819

542317
type: SpeciesReference
stoichiometry: 1.0
species: 456859

456859
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: galactosylgloboside (homo sapiens)_C50H89N2O27FULLRCO

542390
type: SpeciesReference
stoichiometry: 1.0
species: 451696

451696
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Core 2_C22H37N2O15X

542378
type: SpeciesReference
stoichiometry: 1.0
species: 457127

542463
type: SpeciesReference
stoichiometry: 1.0
species: 461994

995604
type: Reaction
reactant: 550320
reversible: false
is: http://identifiers.org/ec-code/3.2.1.20
reactant: 550332
product: 550356
is: ENSBTAG00000008866.4
notes: R_MALT subsystem: Starch and Sucrose Metabolism R_MALT equation: [c] : h2o + malt --> (2) glc-D R_MLTG1 subsystem: Starch and Sucrose Metabolism R_MLTG1 equation: [c] : h2o + malttr --> glc-D + malt
product: 550344
fast: false
reactant: 550308

550320
type: SpeciesReference
stoichiometry: 1.0
species: 463539

463539
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Maltotriose_C18H32O16

550332
type: SpeciesReference
stoichiometry: 2.0
species: 458685

550356
type: SpeciesReference
stoichiometry: 3.0
species: 457356

550344
type: SpeciesReference
stoichiometry: 1.0
species: 463503

550308
type: SpeciesReference
stoichiometry: 1.0
species: 463503

460813
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 21_C132H213N9O114S6

989399
type: Reaction
product: 491692
reactant: 491680
notes: R_GLBRAN subsystem: Starch and Sucrose Metabolism R_GLBRAN equation: [c] : glygn1 --> glygn2
is: ENSBTAG00000036262.2
is: http://identifiers.org/ec-code/2.4.1.18
fast: false
reversible: false
name: _1,4-alpha-glucan branching enzyme (glygn1 -> glygn2)

491692
type: SpeciesReference
stoichiometry: 1.0
species: 457936

457936
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]})_C66H111O56X

491680
type: SpeciesReference
stoichiometry: 1.0
species: 457924

457924
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: glycogen, structure 1 (glycogenin-11[1,4-Glc])_C66H111O56X

987613
type: Reaction
is: ENSBTAG00000005857.4
fast: false
notes: R_ABUTt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_ABUTt4_LPAREN_2_RPAREN_r equation: _4abut[e] + (2) na1[e] <==> 4abut[c] + (2) na1[c]
product: 475249
product: 475261
is: ENSBTAG00000038962.1
is: ENSBTAG00000014525.4
reversible: true
reactant: 475237
reactant: 475225
name: _4-aminobutyrate reversible transport in via sodium symport (1:2)

475249
type: SpeciesReference
stoichiometry: 1.0
species: 445528

475261
type: SpeciesReference
stoichiometry: 2.0
species: 464458

475237
type: SpeciesReference
stoichiometry: 2.0
species: 464470

475225
type: SpeciesReference
stoichiometry: 1.0
species: 445540

444189
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1-Methylpyrrolinium_C5H10N

989831
type: Reaction
notes: R_CITt4_2 subsystem: Transport, Extracellular R_CITt4_2 equation: cit[e] + (2) na1[e] <==> cit[c] + (2) na1[c] R_SUCCt4_2 subsystem: Transport, Extracellular R_SUCCt4_2 equation: (2) na1[e] + succ[e] <==> (2) na1[c] + succ[c]
reactant: 495526
reversible: true
fast: false
product: 495575
reactant: 495539
product: 495563
reactant: 495514
product: 495551
is: ENSBTAG00000008788.4

495526
type: SpeciesReference
stoichiometry: 1.0
species: 469178

495575
type: SpeciesReference
stoichiometry: 1.0
species: 451217

495539
type: SpeciesReference
stoichiometry: 1.0
species: 451229

451229
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Citrate_C6H5O7

495563
type: SpeciesReference
stoichiometry: 4.0
species: 464458

495514
type: SpeciesReference
stoichiometry: 4.0
species: 464470

495551
type: SpeciesReference
stoichiometry: 1.0
species: 469166

997575
type: Reaction
reversible: false
reactant: 570274
product: 570348
reactant: 570299
reactant: 570286
is: ENSBTAG00000020416.4
notes: R_GPIDAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIDAer equation: [r] : gpi_prot_hs + h2o --> dgpi_prot_hs + h + hdca R_GPIDA2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIDA2er equation: [r] : em2emgacpail_prot_hs + h2o --> dem2emgacpail_prot_hs + h + hdca
product: 570336
product: 570324
fast: false
product: 570311

570274
type: SpeciesReference
stoichiometry: 2.0
species: 458758

570348
type: SpeciesReference
stoichiometry: 2.0
species: 458867

570299
type: SpeciesReference
stoichiometry: 1.0
species: 455160

570286
type: SpeciesReference
stoichiometry: 1.0
species: 458203

570336
type: SpeciesReference
stoichiometry: 1.0
species: 453554

453554
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: deacylated-glycophosphatidylinositol (GPI)-anchored protein_C39H76N4O37P4FULLRCO2FULLR2CO2X

570324
type: SpeciesReference
stoichiometry: 1.0
species: 453444

453444
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622

570311
type: SpeciesReference
stoichiometry: 2.0
species: 459037

459037
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Hexadecanoate (n-C16:0)_C16H31O2

454451
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Dolichyl phosphate D-mannose, human uterine homolog_C1085H1780O90P10

447737
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Acetol_C3H6O2

453072
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Decanoyl-CoA (n-C10:0CoA)_C31H50N7O17P3S

464482
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Sodium_Na

990960
type: Reaction
product: 505240
product: 505216
reactant: 505180
fast: false
reversible: false
is: ENSBTAG00000003504.2
is: http://identifiers.org/ec-code/6.3.2.3
product: 505228
reactant: 505192
notes: R_GTHS subsystem: Glutathione Metabolism R_GTHS equation: [c] : atp + glucys + gly --> adp + gthrd + h + pi
product: 505204
name: glutathione synthetase
reactant: 505168

505240
type: SpeciesReference
stoichiometry: 1.0
species: 458794

505216
type: SpeciesReference
stoichiometry: 1.0
species: 448462

505180
type: SpeciesReference
stoichiometry: 1.0
species: 449983

505228
type: SpeciesReference
stoichiometry: 1.0
species: 458456

505192
type: SpeciesReference
stoichiometry: 1.0
species: 457598

457598
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: gamma-L-Glutamyl-L-cysteine_C8H13N2O5S

505204
type: SpeciesReference
stoichiometry: 1.0
species: 466736

505168
type: SpeciesReference
stoichiometry: 1.0
species: 457707

998060
type: Reaction
product: 574581
fast: false
reversible: false
reactant: 574544
is: ENSBTAG00000031332.2
product: 574593
product: 574605
is: http://identifiers.org/ec-code/2.7.1.15
notes: R_RBK subsystem: Pentose Phosphate Pathway R_RBK equation: [c] : atp + rib-D --> adp + h + r5p R_DRBK subsystem: Pentose Phosphate Pathway R_DRBK equation: [c] : atp + drib --> 2dr5p + adp + h
reactant: 574557
reactant: 574569
product: 574617

574581
type: SpeciesReference
stoichiometry: 1.0
species: 468030

468030
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: alpha-D-Ribose 5-phosphate_C5H9O8P

574544
type: SpeciesReference
stoichiometry: 1.0
species: 468200

468200
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Ribose_C5H10O5

574593
type: SpeciesReference
stoichiometry: 2.0
species: 448462

574605
type: SpeciesReference
stoichiometry: 1.0
species: 444455

574557
type: SpeciesReference
stoichiometry: 2.0
species: 449983

574569
type: SpeciesReference
stoichiometry: 1.0
species: 454595

574617
type: SpeciesReference
stoichiometry: 2.0
species: 458794

459097
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Hexadecenoyl-CoA (n-C16:1CoA)_C37H60N7O17P3S

467680
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: phosphatidylserine (homo sapiens)_C6H11NO6PFULLRCO2FULLR2CO2

470923
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: UDP-D-xylose_C14H20N2O16P2

454715
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: dTMP_C10H13N2O8P

445649
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4 hydroxy debrisoquine_C10H14N3O

989507
type: Reaction
name: alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
is: ENSBTAG00000001546.3
fast: false
notes: R_M13N2Tg subsystem: N-Glycan Biosynthesis R_M13N2Tg equation: [g] : m4masn + uacgam --> h + nm4masn + udp
is: http://identifiers.org/ec-code/2.4.1.101
product: 492909
product: 492935
reversible: false
reactant: 492883
reactant: 492896
product: 492922

492909
type: SpeciesReference
stoichiometry: 1.0
species: 470688

492935
type: SpeciesReference
stoichiometry: 1.0
species: 464978

464978
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C54H90N3O40X

492883
type: SpeciesReference
stoichiometry: 1.0
species: 463081

492896
type: SpeciesReference
stoichiometry: 1.0
species: 470652

492922
type: SpeciesReference
stoichiometry: 1.0
species: 458819

471637
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: cholesterol ester_C27H45XCO2

445011
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _3-Hydroxypropionyl-CoA_C24H36N7O18P3S

461662
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate II (core 2-linked), degradation product 3_C58H94N5O46S2X

446094
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: pentaglutamyl folate (DHF)_C39H43N11O18

992161
type: Reaction
is: http://identifiers.org/ec-code/3.6.1.7
reactant: 517719
reversible: false
is: ENSBTAG00000006852.3
product: 517755
notes: R_ACYP subsystem: Glycolysis/Gluconeogenesis R_ACYP equation: [c] : 13dpg + h2o --> 3pg + h + pi
product: 517743
is: ENSBTAG00000013992.3
reactant: 517707
product: 517731
fast: false
name: acylphosphatase
is: ENSBTAG00000015911.3

517719
type: SpeciesReference
stoichiometry: 1.0
species: 458685

517755
type: SpeciesReference
stoichiometry: 1.0
species: 458794

517743
type: SpeciesReference
stoichiometry: 1.0
species: 445323

517707
type: SpeciesReference
stoichiometry: 1.0
species: 444057

517731
type: SpeciesReference
stoichiometry: 1.0
species: 466736

449813
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Arginine_C6H15N4O2

451913
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Carnitine_C7H15NO3

443851
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _10-Formyltetrahydrofolate_C20H21N7O7

469866
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: trihexosyl ceramide (homo sapiens)_C36H66NO17FULLRCO

454800
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: dUDP_C9H11N2O11P2

469310
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: triacylglycerol (homo sapiens)_C3H5FULLRCO2FULLR2CO2FULLR3CO2

467086
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Diphosphoinositol tetrakisphosphate_C6H7O24P6

470459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: testosterone sulfate_C19H27O5S

453662
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Dihydroxyacetone phosphate_C3H5O6P

459673
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: heparan sulfate, degradation product 21_C37H55NO38S2

991476
type: Reaction
reactant: 509933
notes: R_THD1m subsystem: NAD Metabolism R_THD1m equation: h[c] + nadh[m] + nadp[m] <==> h[m] + nad[m] + nadph[m]
is: ENSBTAG00000011885.3
reactant: 509945
product: 509969
reversible: true
product: 509994
product: 509981
reactant: 509957
is: http://identifiers.org/ec-code/1.6.1.1
name: NAD(P) transhydrogenase
fast: false

509933
type: SpeciesReference
stoichiometry: 1.0
species: 464663

509945
type: SpeciesReference
stoichiometry: 1.0
species: 458794

509969
type: SpeciesReference
stoichiometry: 1.0
species: 464542

509994
type: SpeciesReference
stoichiometry: 1.0
species: 458843

509981
type: SpeciesReference
stoichiometry: 1.0
species: 464723

509957
type: SpeciesReference
stoichiometry: 1.0
species: 464602

450503
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: cervonyl carnitine_C29H45NO4

996955
type: Reaction
is: ENSBTAG00000010062.4
product: 562820
product: 562796
reversible: false
reactant: 562772
product: 562808
reactant: 562784
product: 562832
notes: R_CLI2tex subsystem: Transport, Extracellular R_CLI2tex equation: cl[e] + (2) i[c] --> cl[c] + (2) i[e] R_CLHCOtex subsystem: Transport, Extracellular R_CLHCOtex equation: cl[e] + (2) hco3[c] --> cl[c] + (2) hco3[e] R_CLFORtex subsystem: Transport, Extracellular R_CLFORtex equation: cl[e] + (2) for[c] --> cl[c] + (2) for[e]
reactant: 562760
fast: false
reactant: 562748

562820
type: SpeciesReference
stoichiometry: 2.0
species: 460133

562796
type: SpeciesReference
stoichiometry: 2.0
species: 455871

455871
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Formate_CH1O2

562772
type: SpeciesReference
stoichiometry: 2.0
species: 460121

460121
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Iodide_I

562808
type: SpeciesReference
stoichiometry: 3.0
species: 451277

562784
type: SpeciesReference
stoichiometry: 3.0
species: 451289

562832
type: SpeciesReference
stoichiometry: 2.0
species: 458964

562760
type: SpeciesReference
stoichiometry: 2.0
species: 455859

562748
type: SpeciesReference
stoichiometry: 2.0
species: 458952

997964
type: Reaction
notes: R_DHPM1 subsystem: Pyrimidine Catabolism R_DHPM1 equation: [c] : 56dura + h2o --> cala + h
product: 573549
fast: false
is: ENSBTAG00000018373.3
name: dihydropyrimidinase (5,6-dihydrouracil)
reversible: false
is: http://identifiers.org/ec-code/3.5.2.2
product: 573537
is: ENSBTAG00000010661.3
reactant: 573513
is: ENSBTAG00000021887.3
reactant: 573525

573549
type: SpeciesReference
stoichiometry: 1.0
species: 458794

573537
type: SpeciesReference
stoichiometry: 1.0
species: 450563

450563
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Carbamoyl-beta-alanine_C4H7N2O3

573513
type: SpeciesReference
stoichiometry: 1.0
species: 445950

445950
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5,6-dihydrouracil_C4H6N2O2

573525
type: SpeciesReference
stoichiometry: 1.0
species: 458685

462526
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: lignoceryl carnitine_C31H61NO4

468431
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Sarcosine_C3H7NO2

445299
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: _3-Oxotetradecanoyl-CoA_C35H56N7O18P3S

465937
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: _1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens)_C11H23O4NPFULLRCO2

990732
type: Reaction
is: http://identifiers.org/ec-code/2.3.2.4
fast: false
name: gamma-glutamylcyclotransferase
product: 502724
is: ENSBTAG00000010597.3
reversible: false
product: 502736
notes: R_GGLUCT subsystem: Glutathione Metabolism R_GGLUCT equation: gluala[e] --> 5oxpro[c] + ala-L[c]
reactant: 502712

502724
type: SpeciesReference
stoichiometry: 1.0
species: 446382

446382
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-Oxoproline_C5H6NO3

502736
type: SpeciesReference
stoichiometry: 1.0
species: 449091

502712
type: SpeciesReference
stoichiometry: 1.0
species: 457586

987889
type: Reaction
reactant: 477531
reactant: 477519
product: 477543
is: ENSBTAG00000002490.3
reversible: false
fast: false
notes: R_CEPTC subsystem: Glycerophospholipid Metabolism R_CEPTC equation: [c] : cdpchol + dag_hs --> cmp + h + pchol_hs
product: 477555
product: 477567
name: choline phosphotransferase

477531
type: SpeciesReference
stoichiometry: 1.0
species: 450768

450768
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: CDPcholine_C14H25N4O11P2

477519
type: SpeciesReference
stoichiometry: 1.0
species: 452951

477543
type: SpeciesReference
stoichiometry: 1.0
species: 451398

477555
type: SpeciesReference
stoichiometry: 1.0
species: 466238

477567
type: SpeciesReference
stoichiometry: 1.0
species: 458794

447117
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: R total 2 carnitine_CO2FULLR2C7H14NO2

445083
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Iodo-L-tyrosine_C9H10INO3

450707
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Carbamoyl phosphate_CH2NO5P

988478
type: Reaction
is: ENSBTAG00000016234.4
product: 482596
reactant: 482572
reactant: 482548
notes: R_H2O2syn subsystem: Tyrosine metabolism R_H2O2syn equation: [c] : h + nadph + o2 --> h2o2 + nadp
name: Hydrogen peroxide synthesis (NADPH dependent)
product: 482584
fast: false
reactant: 482560
is: ENSBTAG00000016246.3
reversible: false

482596
type: SpeciesReference
stoichiometry: 1.0
species: 458613

458613
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Hydrogen peroxide_H2O2

482572
type: SpeciesReference
stoichiometry: 1.0
species: 464711

482548
type: SpeciesReference
stoichiometry: 1.0
species: 465234

482584
type: SpeciesReference
stoichiometry: 1.0
species: 464639

482560
type: SpeciesReference
stoichiometry: 1.0
species: 458794

471709
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane_C27H48O3

446058
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate_C9H11N3O9P

468407
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Sarcosine_C3H7NO2

452783
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Cysteine_C3H7NO2S

447797
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: N-Acetyl-L-glutamate 5-semialdehyde_C7H10NO4

991548
type: Reaction
notes: R_S6T25g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T25g equation: [g] : hs_pre12 + (3) paps --> (3) h + hs_pre13 + (3) pap
is: ENSBTAG00000006157.4
product: 510480
name: heparan sulfate 6-sulfotransferase, Golgi apparatus
fast: false
reactant: 510456
reversible: false
product: 510492
reactant: 510444
product: 510468

510480
type: SpeciesReference
stoichiometry: 3.0
species: 466202

510456
type: SpeciesReference
stoichiometry: 1.0
species: 459866

459866
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: heparan sulfate, precursor 12_C79H119N5O83S6X

510492
type: SpeciesReference
stoichiometry: 1.0
species: 459878

459878
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: heparan sulfate, precursor 13_C79H116N5O92S9X

510444
type: SpeciesReference
stoichiometry: 3.0
species: 466226

510468
type: SpeciesReference
stoichiometry: 3.0
species: 458819

458094
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GMP_C10H12N5O8P

467158
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Inorganic triphosphate_HO10P3

993686
type: Reaction
reactant: 530591
reactant: 530506
reactant: 530482
product: 530724
reactant: 530445
product: 530628
product: 530748
product: 530784
fast: false
reactant: 530433
notes: R_3MOXTYROX subsystem: Tyrosine metabolism R_3MOXTYROX equation: [c] : 3moxtyr + h2o + o2 --> 3mox4hpac + h2o2 + nh4 R_MAOLNOR subsystem: Tyrosine metabolism R_MAOLNOR equation: [c] : h2o + normete-L + o2 --> 3m4hpga + h2o2 + nh4 R_APRTO2 subsystem: Arginine and Proline Metabolism R_APRTO2 equation: [c] : aprut + h2o + o2 --> h2o2 + n4abutn + nh4 R_42A12BOOX subsystem: Tyrosine metabolism R_42A12BOOX equation: [c] : dopa + h2o + o2 --> 34dhpac + h2o2 + nh4 R_PEAMNO subsystem: Phenylalanine metabolism R_PEAMNO equation: [c] : h2o + o2 + peamn --> h2o2 + nh4 + pacald R_MACOXO subsystem: Histidine Metabolism R_MACOXO equation: [c] : 3mldz + h2o + nad --> 3mlda + (2) h + nadh R_3HXKYNOXDA subsystem: Tryptophan metabolism R_3HXKYNOXDA equation: [c] : 3hxkynam + o2 --> 48dhoxquin + h2o2 + nh4 R_41R2A1H12BOOX subsystem: Tyrosine metabolism R_41R2A1H12BOOX equation: [c] : h2o + nrpphr + o2 --> 34dhmald + h2o2 + nh4 R_TRYPTAOX subsystem: Tryptophan metabolism R_TRYPTAOX equation: [c] : h2o + o2 + trypta --> h2o2 + id3acald + nh4 R_5HXKYNOXDA subsystem: Tryptophan metabolism R_5HXKYNOXDA equation: [c] : 5hxkynam + o2 --> 46dhoxquin + h2o2 + nh4 R_TYROXDAc subsystem: Tyrosine metabolism R_TYROXDAc equation: [c] : h2o + o2 + tym --> 4hoxpacd + h2o2 + nh4 R_5HOXINOXDA subsystem: Tryptophan metabolism R_5HOXINOXDA equation: [c] : h2o + o2 + srtn --> 5hoxindact + h2o2 + nh4 R_41R1H2MAE12BOOX subsystem: Tyrosine metabolism R_41R1H2MAE12BOOX equation: [c] : adrnl + h2o + o2 --> 34dhmald + h2o2 + mma
product: 530700
reversible: false
product: 530664
reactant: 530519
is: ENSBTAG00000001288.4
reactant: 530458
is: http://identifiers.org/ec-code/1.2.1.5
product: 530820
reactant: 530615
reactant: 530470
product: 530688
reactant: 530579
product: 530640
is: http://identifiers.org/ec-code/1.4.3.6
product: 530796
product: 530760
product: 530712
reactant: 530567
product: 530676
product: 530736
product: 530808
product: 530772
reactant: 530543
is: http://identifiers.org/ec-code/1.4.3.4
reactant: 530603
reactant: 530494
reactant: 530531
reactant: 530555
product: 530652

530591
type: SpeciesReference
stoichiometry: 11.0
species: 458685

530506
type: SpeciesReference
stoichiometry: 1.0
species: 470579

530482
type: SpeciesReference
stoichiometry: 1.0
species: 448705

530724
type: SpeciesReference
stoichiometry: 1.0
species: 446214

446214
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-Hydroxyindoleacetaldehyde_C10H9NO2

530445
type: SpeciesReference
stoichiometry: 1.0
species: 445143

530628
type: SpeciesReference
stoichiometry: 1.0
species: 445215

445215
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Methoxy-4-hydroxyphenylacetaldehyde_C9H10O3

530748
type: SpeciesReference
stoichiometry: 12.0
species: 458613

530784
type: SpeciesReference
stoichiometry: 2.0
species: 458794

530433
type: SpeciesReference
stoichiometry: 1.0
species: 465087

530700
type: SpeciesReference
stoichiometry: 1.0
species: 445131

445131
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Methylimidazoleacetic acid_C6H7N2O2

530664
type: SpeciesReference
stoichiometry: 1.0
species: 444671

530519
type: SpeciesReference
stoichiometry: 1.0
species: 445227

530458
type: SpeciesReference
stoichiometry: 1.0
species: 465063

530820
type: SpeciesReference
stoichiometry: 1.0
species: 464590

530615
type: SpeciesReference
stoichiometry: 1.0
species: 449573

449573
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Acetylputrescine_C6H15N2O

530470
type: SpeciesReference
stoichiometry: 1.0
species: 464518

530688
type: SpeciesReference
stoichiometry: 1.0
species: 464169

464169
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Methylamine_C1H6N

530579
type: SpeciesReference
stoichiometry: 1.0
species: 454523

530640
type: SpeciesReference
stoichiometry: 1.0
species: 464422

464422
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N4-Acetylaminobutanal_C6H11NO2

530796
type: SpeciesReference
stoichiometry: 2.0
species: 444635

530760
type: SpeciesReference
stoichiometry: 1.0
species: 460193

460193
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Indole-3-acetaldehyde_C10H9NO

530712
type: SpeciesReference
stoichiometry: 1.0
species: 445095

530567
type: SpeciesReference
stoichiometry: 1.0
species: 445071

530676
type: SpeciesReference
stoichiometry: 11.0
species: 464834

530736
type: SpeciesReference
stoichiometry: 1.0
species: 465913

465913
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Phenylacetaldehyde_C8H8O

530808
type: SpeciesReference
stoichiometry: 1.0
species: 445480

530772
type: SpeciesReference
stoichiometry: 1.0
species: 445492

445492
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4,8-Dihydroxyquinoline_C9H7NO2

530543
type: SpeciesReference
stoichiometry: 1.0
species: 446310

530603
type: SpeciesReference
stoichiometry: 12.0
species: 465234

530494
type: SpeciesReference
stoichiometry: 1.0
species: 470385

530531
type: SpeciesReference
stoichiometry: 1.0
species: 466435

530555
type: SpeciesReference
stoichiometry: 1.0
species: 468984

530652
type: SpeciesReference
stoichiometry: 1.0
species: 445673

445673
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-Hydroxyphenylacetaldehyde_C8H8O2

992245
type: Reaction
notes: R_ADSL2 subsystem: IMP Biosynthesis R_ADSL2 equation: [c] : 25aics --> aicar + fum R_ADSL1 subsystem: Nucleotides R_ADSL1 equation: [c] : dcamp --> amp + fum
is: ENSBTAG00000000077.4
product: 518337
product: 518349
is: http://identifiers.org/ec-code/4.3.2.2
reactant: 518313
reversible: false
is: ENSBTAG00000008477.4
reactant: 518325
product: 518361
fast: false

518337
type: SpeciesReference
stoichiometry: 1.0
species: 448885

448885
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide_C9H13N4O8P

518349
type: SpeciesReference
stoichiometry: 2.0
species: 456354

456354
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Fumarate_C4H2O4

518313
type: SpeciesReference
stoichiometry: 1.0
species: 444298

444298
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate_C13H15N4O12P

518325
type: SpeciesReference
stoichiometry: 1.0
species: 453084

453084
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N6-(1,2-Dicarboxyethyl)-AMP_C14H14N5O11P

518361
type: SpeciesReference
stoichiometry: 1.0
species: 449296

989114
type: Reaction
is: ENSBTAG00000006928.3
is: http://identifiers.org/ec-code/2.6.1.13
fast: false
reactant: 489146
product: 489170
product: 489183
reactant: 489158
notes: R_ORNTArm subsystem: Urea cycle/amino group metabolism R_ORNTArm equation: [m] : akg + orn <==> glu-L + glu5sa
reversible: true
name: ornithine transaminase reversible (m)

489146
type: SpeciesReference
stoichiometry: 1.0
species: 465767

465767
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Ornithine_C5H13N2O2

489170
type: SpeciesReference
stoichiometry: 1.0
species: 457562

489183
type: SpeciesReference
stoichiometry: 1.0
species: 457513

457513
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Glutamate 5-semialdehyde_C5H9NO3

489158
type: SpeciesReference
stoichiometry: 1.0
species: 448970

447882
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Type IIIAb_C92H158N5O55FULLRCO

453506
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: dGDP_C10H12N5O10P2

461359
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 22_C185H297N13O150S6X

996097
type: Reaction
notes: R_FUMAC subsystem: Tyrosine metabolism R_FUMAC equation: [c] : 4fumacac + h2o --> acac + fum + h
product: 555855
name: fumarylacetoacetase
reactant: 555819
reactant: 555831
reversible: false
is: http://identifiers.org/ec-code/3.7.1.2
product: 555867
fast: false
is: ENSBTAG00000012338.3
product: 555843

555855
type: SpeciesReference
stoichiometry: 1.0
species: 447569

555819
type: SpeciesReference
stoichiometry: 1.0
species: 445601

555831
type: SpeciesReference
stoichiometry: 1.0
species: 458685

555867
type: SpeciesReference
stoichiometry: 1.0
species: 458794

555843
type: SpeciesReference
stoichiometry: 1.0
species: 456354

443791
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _10-formyltetrahydrofolate-[Glu](6)_C45H51N12O22

989795
type: Reaction
notes: R_RNDR1 subsystem: Nucleotides R_RNDR1 equation: [c] : adp + trdrd --> dadp + h2o + trdox R_RNDR3 subsystem: Nucleotides R_RNDR3 equation: [c] : cdp + trdrd --> dcdp + h2o + trdox R_RNDR2 subsystem: Nucleotides R_RNDR2 equation: [c] : gdp + trdrd --> dgdp + h2o + trdox R_RNDR4 subsystem: Nucleotides R_RNDR4 equation: [c] : trdrd + udp --> dudp + h2o + trdox
product: 495113
product: 495149
product: 495100
product: 495088
product: 495137
is: ENSBTAG00000013111.4
reactant: 495040
is: ENSBTAG00000008216.4
reactant: 495064
reactant: 495052
fast: false
reversible: false
reactant: 495028
reactant: 495076
is: http://identifiers.org/ec-code/1.17.4.1
product: 495125

495113
type: SpeciesReference
stoichiometry: 4.0
species: 470252

470252
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Oxidized thioredoxin_X

495149
type: SpeciesReference
stoichiometry: 1.0
species: 453482

495100
type: SpeciesReference
stoichiometry: 1.0
species: 454788

495088
type: SpeciesReference
stoichiometry: 1.0
species: 452915

495137
type: SpeciesReference
stoichiometry: 4.0
species: 458685

495040
type: SpeciesReference
stoichiometry: 1.0
species: 457199

495064
type: SpeciesReference
stoichiometry: 1.0
species: 470664

495052
type: SpeciesReference
stoichiometry: 1.0
species: 448462

495028
type: SpeciesReference
stoichiometry: 4.0
species: 470276

470276
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Reduced thioredoxin_XH2

495076
type: SpeciesReference
stoichiometry: 1.0
species: 450732

495125
type: SpeciesReference
stoichiometry: 1.0
species: 453096

991296
type: Reaction
reactant: 508312
name: _6,7-dihydropteridine reductase
is: ENSBTAG00000040333.1
notes: R_DHPR subsystem: Tetrahydrobiopterin R_DHPR equation: [c] : dhbpt + h + nadh --> nad + thbpt
reversible: false
fast: false
reactant: 508288
product: 508337
product: 508325
reactant: 508300
is: ENSBTAG00000003356.4

508312
type: SpeciesReference
stoichiometry: 1.0
species: 464590

508288
type: SpeciesReference
stoichiometry: 1.0
species: 453674

508337
type: SpeciesReference
stoichiometry: 1.0
species: 464518

508325
type: SpeciesReference
stoichiometry: 1.0
species: 469769

508300
type: SpeciesReference
stoichiometry: 1.0
species: 458794

989303
type: Reaction
product: 491137
product: 491173
fast: false
reactant: 491113
product: 491161
reactant: 491125
reactant: 491101
reversible: false
product: 491149
is: http://identifiers.org/ec-code/2.4.1.102
is: ENSBTAG00000012757.3
notes: R_CORE2GTg subsystem: O-Glycan Biosynthesis R_CORE2GTg equation: [g] : T_antigen + uacgam --> core2 + h + udp R_CORE6GTg subsystem: O-Glycan Biosynthesis R_CORE6GTg equation: [g] : Tn_antigen + uacgam --> core6 + h + udp

491137
type: SpeciesReference
stoichiometry: 2.0
species: 470688

491173
type: SpeciesReference
stoichiometry: 1.0
species: 451696

491113
type: SpeciesReference
stoichiometry: 1.0
species: 447387

491161
type: SpeciesReference
stoichiometry: 1.0
species: 451732

451732
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Core 6_C16H27N2O10X

491125
type: SpeciesReference
stoichiometry: 1.0
species: 447400

491101
type: SpeciesReference
stoichiometry: 2.0
species: 470652

491149
type: SpeciesReference
stoichiometry: 2.0
species: 458819

996229
type: Reaction
is: http://identifiers.org/ec-code/2.4.1.212
notes: R_HAS1 subsystem: Hyaluronan Metabolism R_HAS1 equation: uacgam[c] + udpglcur[c] --> (2) h[c] + ha_pre1[e] + (2) udp[c] R_HAS2 subsystem: Hyaluronan Metabolism R_HAS2 equation: ha_pre1[e] + uacgam[c] + udpglcur[c] --> (2) h[c] + ha[e] + (2) udp[c]
fast: false
is: ENSBTAG00000007992.4
product: 557104
reversible: false
reactant: 557068
product: 557116
product: 557080
product: 557092
reactant: 557044
is: ENSBTAG00000019892.3
is: ENSBTAG00000017672.4
is: ENSBTAG00000033601.2
reactant: 557056

557104
type: SpeciesReference
stoichiometry: 4.0
species: 470664

557068
type: SpeciesReference
stoichiometry: 2.0
species: 470860

470860
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: UDP-D-glucuronate_C15H19N2O18P2

557116
type: SpeciesReference
stoichiometry: 4.0
species: 458794

557080
type: SpeciesReference
stoichiometry: 1.0
species: 458928

458928
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: hyaluronan biosynthesis, precursor 1_C14H20NO11

557092
type: SpeciesReference
stoichiometry: 1.0
species: 458903

458903
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: hyaluronan_C28H40N2O22

557044
type: SpeciesReference
stoichiometry: 1.0
species: 458928

557056
type: SpeciesReference
stoichiometry: 2.0
species: 470640

460923
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 2_C241H384N17O210S12

447274
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: R total Coenzyme A_CO2FULLRC21H31N7O15P3S

454355
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Dolichol diphosphate, human liver homolog_C1080H1758O70P20

992965
type: Reaction
product: 525040
reactant: 524847
reactant: 524727
reactant: 524811
product: 525052
is: http://identifiers.org/ec-code/1.2.1.4
product: 525064
reactant: 524835
reactant: 524751
product: 525076
is: ENSBTAG00000017852.3
product: 525004
reactant: 524775
is: http://identifiers.org/ec-code/1.2.1.19
product: 525016
reactant: 524691
product: 525028
product: 524931
product: 524943
reactant: 524859
reactant: 524715
product: 524980
reactant: 524703
product: 524992
is: http://identifiers.org/ec-code/1.2.1.21
product: 524883
product: 524968
reactant: 524739
reactant: 524763
notes: R_BETALDHx subsystem: Glycine, Serine, and Threonine Metabolism R_BETALDHx equation: [c] : betald + h2o + nad --> glyb + (2) h + nadh R_ALDD2y subsystem: Glycolysis/Gluconeogenesis R_ALDD2y equation: [c] : acald + h2o + nadp --> ac + (2) h + nadph R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD20x subsystem: Tryptophan metabolism R_ALDD20x equation: [c] : h2o + id3acald + nad --> (2) h + ind3ac + nadh R_BAMPPALDOX subsystem: beta-Alanine metabolism R_BAMPPALDOX equation: [c] : bamppald + h2o + nad --> ala-B + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_IMACTD subsystem: Histidine Metabolism R_IMACTD equation: [c] : h2o + im4act + nad --> (2) h + im4ac + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_PYLALDOX subsystem: Limonene and pinene degradation R_PYLALDOX equation: [c] : h2o + nad + pylald --> (2) h + nadh + peracd R_NABTNO subsystem: Arginine and Proline Metabolism R_NABTNO equation: [c] : h2o + n4abutn + nad --> 4aabutn + (2) h + nadh R_ABUTD subsystem: beta-Alanine metabolism R_ABUTD equation: [c] : 4abutn + h2o + nad --> 4abut + (2) h + nadh R_5HOXINDACTOX subsystem: Tryptophan metabolism R_5HOXINDACTOX equation: [c] : 5hoxindact + h2o + nad --> 5hoxindoa + (2) h + nadh R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_TMABADH subsystem: Lysine Metabolism R_TMABADH equation: [c] : 4tmeabut + h2o + nad --> 4tmeabutn + (2) h + nadh R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh
reactant: 524823
product: 524895
product: 524907
is: http://identifiers.org/ec-code/1.2.1.8
fast: false
reactant: 524799
reactant: 524871
product: 524919
reactant: 524787
is: http://identifiers.org/ec-code/1.2.1.47
reactant: 524679
product: 524956
reversible: false
is: http://identifiers.org/ec-code/1.2.1.3

525040
type: SpeciesReference
stoichiometry: 1.0
species: 462138

524847
type: SpeciesReference
stoichiometry: 16.0
species: 458685

524727
type: SpeciesReference
stoichiometry: 1.0
species: 467885

467885
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Perillyl aldehyde_C10H14O

524811
type: SpeciesReference
stoichiometry: 1.0
species: 446214

525052
type: SpeciesReference
stoichiometry: 31.0
species: 458794

525064
type: SpeciesReference
stoichiometry: 1.0
species: 464711

524835
type: SpeciesReference
stoichiometry: 1.0
species: 460193

524751
type: SpeciesReference
stoichiometry: 1.0
species: 457031

457031
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Glycolaldehyde_C2H4O2

525076
type: SpeciesReference
stoichiometry: 14.0
species: 464590

525004
type: SpeciesReference
stoichiometry: 1.0
species: 466495

466495
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Perillic acid_C10H13O2

524775
type: SpeciesReference
stoichiometry: 2.0
species: 447617

525016
type: SpeciesReference
stoichiometry: 1.0
species: 445914

524691
type: SpeciesReference
stoichiometry: 1.0
species: 464422

525028
type: SpeciesReference
stoichiometry: 1.0
species: 449006

449006
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: beta-Alanine_C3H7NO2

524931
type: SpeciesReference
stoichiometry: 2.0
species: 447521

524943
type: SpeciesReference
stoichiometry: 1.0
species: 445504

445504
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-Acetamidobutanoate_C6H10NO3

524859
type: SpeciesReference
stoichiometry: 1.0
species: 457332

457332
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-glucurono-6,3-lactone_C6H8O6

524715
type: SpeciesReference
stoichiometry: 1.0
species: 460352

460352
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Imidazole-4-acetaldehyde_C5H6N2O

524980
type: SpeciesReference
stoichiometry: 1.0
species: 457779

524703
type: SpeciesReference
stoichiometry: 1.0
species: 445577

445577
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-Aminobutanal_C4H10NO

524992
type: SpeciesReference
stoichiometry: 1.0
species: 462174

524883
type: SpeciesReference
stoichiometry: 1.0
species: 460327

460327
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Imidazole-4-acetate_C5H5N2O2

524968
type: SpeciesReference
stoichiometry: 1.0
species: 446238

524739
type: SpeciesReference
stoichiometry: 14.0
species: 464518

524763
type: SpeciesReference
stoichiometry: 1.0
species: 445890

445890
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-Trimethylammoniobutanal_C7H16NO

524823
type: SpeciesReference
stoichiometry: 1.0
species: 464639

524895
type: SpeciesReference
stoichiometry: 1.0
species: 457888

457888
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Glycolate_C2H3O3

524907
type: SpeciesReference
stoichiometry: 1.0
species: 445528

524799
type: SpeciesReference
stoichiometry: 1.0
species: 450116

450116
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Betaine aldehyde_C5H12NO

524871
type: SpeciesReference
stoichiometry: 1.0
species: 462210

524919
type: SpeciesReference
stoichiometry: 1.0
species: 460401

460401
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Indole-3-acetate_C10H8NO2

524787
type: SpeciesReference
stoichiometry: 1.0
species: 450080

450080
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: beta-Aminopropion aldehyde_C3H8NO

524679
type: SpeciesReference
stoichiometry: 1.0
species: 462234

524956
type: SpeciesReference
stoichiometry: 1.0
species: 457416

457416
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Glucarate_C6H8O8

990264
type: Reaction
reactant: 499080
reactant: 499056
product: 499105
reactant: 499020
product: 499117
notes: R_UDPGP subsystem: Starch and Sucrose Metabolism R_UDPGP equation: [c] : h2o + udpg --> g1p + (2) h + ump R_NNAT subsystem: NAD Metabolism R_NNAT equation: [c] : atp + h + nicrnt --> dnad + ppi R_DNADDP subsystem: NAD Metabolism R_DNADDP equation: [c] : dnad + h2o --> amp + (2) h + nicrnt R_FADDP subsystem: Riboflavin Metabolism R_FADDP equation: [c] : fad + h2o --> amp + fmn + (2) h
fast: false
is: http://identifiers.org/ec-code/2.7.7.18
reversible: false
reactant: 499068
product: 499178
reactant: 499044
reactant: 499032
product: 499142
product: 499093
reactant: 499008
is: ENSBTAG00000021830.4
product: 499154
product: 499129
is: http://identifiers.org/ec-code/3.6.1.9
product: 499166

499080
type: SpeciesReference
stoichiometry: 1.0
species: 454318

499056
type: SpeciesReference
stoichiometry: 3.0
species: 458685

499105
type: SpeciesReference
stoichiometry: 1.0
species: 470936

499020
type: SpeciesReference
stoichiometry: 1.0
species: 464918

499117
type: SpeciesReference
stoichiometry: 1.0
species: 456451

499068
type: SpeciesReference
stoichiometry: 1.0
species: 458794

499178
type: SpeciesReference
stoichiometry: 1.0
species: 467000

499044
type: SpeciesReference
stoichiometry: 1.0
species: 449983

499032
type: SpeciesReference
stoichiometry: 1.0
species: 470800

499142
type: SpeciesReference
stoichiometry: 2.0
species: 449296

499093
type: SpeciesReference
stoichiometry: 1.0
species: 464918

499008
type: SpeciesReference
stoichiometry: 1.0
species: 455558

499154
type: SpeciesReference
stoichiometry: 6.0
species: 458794

499129
type: SpeciesReference
stoichiometry: 1.0
species: 455787

499166
type: SpeciesReference
stoichiometry: 1.0
species: 454318

463273
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein)_C64H107N2O50X

470987
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: UMP_C9H11N2O9P

996241
type: Reaction
fast: false
product: 557188
is: ENSBTAG00000035605.2
is: ENSBTAG00000033414.2
reactant: 557140
is: ENSBTAG00000036135.1
is: ENSBTAG00000023183.2
is: ENSBTAG00000017666.4
reactant: 557128
notes: R_CAMPt subsystem: Transport, Extracellular R_CAMPt equation: atp[c] + camp[c] + h2o[c] --> adp[c] + camp[e] + h[c] + pi[c] R_CGMPt subsystem: Transport, Extracellular R_CGMPt equation: _35cgmp[c] + atp[c] + h2o[c] --> 35cgmp[e] + adp[c] + h[c] + pi[c]
is: ENSBTAG00000033645.1
product: 557225
product: 557213
is: ENSBTAG00000035676.1
reversible: false
product: 557176
is: ENSBTAG00000023181.2
is: ENSBTAG00000040230.1
reactant: 557152
product: 557200
is: ENSBTAG00000038131.1
is: ENSBTAG00000032482.2
reactant: 557164

557188
type: SpeciesReference
stoichiometry: 1.0
species: 450587

557140
type: SpeciesReference
stoichiometry: 2.0
species: 449983

557128
type: SpeciesReference
stoichiometry: 1.0
species: 450575

557225
type: SpeciesReference
stoichiometry: 1.0
species: 444757

444757
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: _3',5'-Cyclic GMP_C10H11N5O7P

557213
type: SpeciesReference
stoichiometry: 2.0
species: 458794

557176
type: SpeciesReference
stoichiometry: 2.0
species: 466736

557152
type: SpeciesReference
stoichiometry: 1.0
species: 444744

557200
type: SpeciesReference
stoichiometry: 2.0
species: 448462

557164
type: SpeciesReference
stoichiometry: 2.0
species: 458685

995508
type: Reaction
product: 549787
reactant: 549691
is: ENSBTAG00000017490.4
product: 549727
reversible: false
product: 549799
reactant: 549643
reactant: 549655
product: 549739
product: 549763
product: 549703
product: 549775
product: 549715
reactant: 549667
notes: R_PCHOLPg_hs subsystem: Glycerophospholipid Metabolism R_PCHOLPg_hs equation: [g] : h2o + pchol_hs --> chol + h + pa_hs R_PCHOLPr_hs subsystem: Glycerophospholipid Metabolism R_PCHOLPr_hs equation: [r] : h2o + pchol_hs --> chol + h + pa_hs R_PCHOLPm_hs subsystem: Glycerophospholipid Metabolism R_PCHOLPm_hs equation: [m] : h2o + pchol_hs --> chol + h + pa_hs
fast: false
product: 549751
reactant: 549631
reactant: 549679
is: http://identifiers.org/ec-code/3.1.4.4

549787
type: SpeciesReference
stoichiometry: 1.0
species: 458867

549691
type: SpeciesReference
stoichiometry: 1.0
species: 466286

466286
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

549727
type: SpeciesReference
stoichiometry: 1.0
species: 465852

465852
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

549799
type: SpeciesReference
stoichiometry: 1.0
species: 458843

549643
type: SpeciesReference
stoichiometry: 1.0
species: 458733

549655
type: SpeciesReference
stoichiometry: 1.0
species: 458709

549739
type: SpeciesReference
stoichiometry: 1.0
species: 450902

450902
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Choline_C5H14NO

549763
type: SpeciesReference
stoichiometry: 1.0
species: 450914

450914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Choline_C5H14NO

549703
type: SpeciesReference
stoichiometry: 1.0
species: 465889

465889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

549775
type: SpeciesReference
stoichiometry: 1.0
species: 450938

549715
type: SpeciesReference
stoichiometry: 1.0
species: 465864

549667
type: SpeciesReference
stoichiometry: 1.0
species: 458758

549751
type: SpeciesReference
stoichiometry: 1.0
species: 458819

549631
type: SpeciesReference
stoichiometry: 1.0
species: 466262

466262
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

549679
type: SpeciesReference
stoichiometry: 1.0
species: 466274

466274
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

443767
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: _10-formyltetrahydrofolate-[Glu](6)_C45H51N12O22

994107
type: Reaction
reactant: 535022
reactant: 534974
product: 535130
product: 535070
reactant: 534938
reactant: 534998
reactant: 534962
product: 535154
product: 535058
reactant: 535010
is: ENSBTAG00000002380.3
product: 535142
product: 535082
is: ENSBTAG00000012525.4
product: 535118
notes: R_ABO7g subsystem: Blood Group Biosynthesis R_ABO7g equation: [g] : fucgalacgalfucgalacglcgal14acglcgalgluside_hs + udpacgal --> acgalfucgalacgalfucgalacglcgal14acglcgalgluside_hs + h + udp R_ABO5g subsystem: Blood Group Biosynthesis R_ABO5g equation: [g] : fucgalacgalfuc12gal14acglcgalgluside_hs + udpacgal --> acgalfucgalacgalfuc12gal14acglcgalgluside_hs + h + udp R_ABO4g subsystem: Blood Group Biosynthesis R_ABO4g equation: [g] : fuc12gal14acglcgalgluside_hs + udpacgal --> acgalfuc12gal14acglcgalgluside_hs + h + udp R_ABO2g subsystem: Blood Group Biosynthesis R_ABO2g equation: [g] : fucgalacglcgalgluside_hs + udpgal --> galfucgalacglcgalgluside_hs + h + udp R_ABO8g subsystem: Blood Group Biosynthesis R_ABO8g equation: [g] : fucgalacglcgal14acglcgalgluside_hs + udpgal --> galfucgalacglcgal14acglcgalgluside_hs + h + udp R_ABO6g subsystem: Blood Group Biosynthesis R_ABO6g equation: [g] : fucgalacglcgal14acglcgalgluside_hs + udpacgal --> acgalfucgalacglcgal14acglcgalgluside_hs + h + udp R_ABO9g subsystem: Blood Group Biosynthesis R_ABO9g equation: [g] : fucfucgalacglcgalacglcgal14acglcgalgluside_hs + (2) udpgal --> galgalfucfucgalacglcgalacglcgal14acglcgalgluside_hs + (2) h + (2) udp R_ABO3g subsystem: Blood Group Biosynthesis R_ABO3g equation: [g] : fuc12gal14acglcgalgluside_hs + udpgal --> galfuc12gal14acglcgalgluside_hs + h + udp R_ABO1g subsystem: Blood Group Biosynthesis R_ABO1g equation: [g] : fucgalacglcgalgluside_hs + udpacgal --> acgalfucgalacglcgalgluside_hs + h + udp
reversible: false
product: 535046
product: 535106
fast: false
reactant: 534986
reactant: 534950
product: 535034
is: ENSBTAG00000030319.2
product: 535094

535022
type: SpeciesReference
stoichiometry: 1.0
species: 456233

534974
type: SpeciesReference
stoichiometry: 2.0
species: 456028

535130
type: SpeciesReference
stoichiometry: 1.0
species: 456797

535070
type: SpeciesReference
stoichiometry: 10.0
species: 458819

534938
type: SpeciesReference
stoichiometry: 1.0
species: 456281

456281
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)4 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)2 (Cer)1_C84H145N4O50FULLRCO

534998
type: SpeciesReference
stoichiometry: 1.0
species: 456269

456269
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Type IIIH glycolipid_C70H122N3O40FULLRCO

534962
type: SpeciesReference
stoichiometry: 2.0
species: 456305

535154
type: SpeciesReference
stoichiometry: 1.0
species: 447906

535058
type: SpeciesReference
stoichiometry: 1.0
species: 456822

456822
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)6 (Glc)1 (GlcNAc)3 (LFuc)2 (Cer)1_C96H165N4O60FULLRCO

535010
type: SpeciesReference
stoichiometry: 5.0
species: 470848

535142
type: SpeciesReference
stoichiometry: 1.0
species: 447882

535082
type: SpeciesReference
stoichiometry: 1.0
species: 447870

447870
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Type IIIA glycolipid_C78H135N4O45FULLRCO

535118
type: SpeciesReference
stoichiometry: 1.0
species: 456785

535046
type: SpeciesReference
stoichiometry: 10.0
species: 470688

535106
type: SpeciesReference
stoichiometry: 1.0
species: 456809

534986
type: SpeciesReference
stoichiometry: 5.0
species: 470763

534950
type: SpeciesReference
stoichiometry: 2.0
species: 456317

535034
type: SpeciesReference
stoichiometry: 1.0
species: 447858

447858
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)2 (GalNAc)1 (Glc)1 (GlcNAc)1 (LFuc)1 (Cer)1_C58H102N3O31FULLRCO

535094
type: SpeciesReference
stoichiometry: 1.0
species: 447894

454160
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: dihomo-gamma-linolenyl carnitine_C27H47NO4

455292
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: _16-Glucuronide-estriol_C24H32O9

446502
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _6-Hydroxymelatonin_C13H16N2O3

451205
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: chitin_C24H41N3O16

993458
type: Reaction
reversible: false
product: 528528
reactant: 528389
reactant: 528365
reactant: 528428
reactant: 528415
product: 528516
product: 528441
product: 528492
product: 528504
reactant: 528402
reactant: 528341
product: 528480
product: 528454
notes: R_FUT15g subsystem: Blood Group Biosynthesis R_FUT15g equation: [g] : galacgalfuc12gal14acglcgalgluside_hs + gdpfuc --> fucgalacgalfuc12gal14acglcgalgluside_hs + gdp + h R_FUT12g subsystem: Blood Group Biosynthesis R_FUT12g equation: [g] : galacglcgalgluside_hs + gdpfuc --> fucgalacglcgalgluside_hs + gdp + h R_FUT17g subsystem: Blood Group Biosynthesis R_FUT17g equation: [g] : galacgalfucgalacglcgal14acglcgalgluside_hs + gdpfuc --> fucgalacgalfucgalacglcgal14acglcgalgluside_hs + gdp + h R_FUT16g subsystem: Blood Group Biosynthesis R_FUT16g equation: [g] : galacglcgal14acglcgalgluside_hs + gdpfuc --> fucgalacglcgal14acglcgalgluside_hs + gdp + h R_FUT11g subsystem: Sphingolipid Metabolism R_FUT11g equation: [g] : galgbside_hs + gdpfuc --> fucgalgbside_hs + gdp + h R_FUT18g subsystem: Blood Group Biosynthesis R_FUT18g equation: [g] : galacglcgalacglcgal14acglcgalgluside_hs + (2) gdpfuc --> fucfucgalacglcgalacglcgal14acglcgalgluside_hs + (2) gdp + (2) h R_FUT14g subsystem: Blood Group Biosynthesis R_FUT14g equation: [g] : gal14acglcgalgluside_hs + gdpfuc --> fuc12gal14acglcgalgluside_hs + gdp + h
reactant: 528377
reactant: 528353
product: 528540
product: 528467
fast: false
is: ENSBTAG00000024497.3
is: http://identifiers.org/ec-code/2.4.1.69

528528
type: SpeciesReference
stoichiometry: 1.0
species: 456269

528389
type: SpeciesReference
stoichiometry: 8.0
species: 457283

528365
type: SpeciesReference
stoichiometry: 1.0
species: 456773

528428
type: SpeciesReference
stoichiometry: 1.0
species: 456737

528415
type: SpeciesReference
stoichiometry: 1.0
species: 456749

456749
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: I-antigen_C72H125N4O42FULLRCO

528516
type: SpeciesReference
stoichiometry: 1.0
species: 456028

528441
type: SpeciesReference
stoichiometry: 1.0
species: 456281

528492
type: SpeciesReference
stoichiometry: 8.0
species: 457223

528504
type: SpeciesReference
stoichiometry: 1.0
species: 456305

528402
type: SpeciesReference
stoichiometry: 1.0
species: 456701

456701
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)3 (GalNAc)1 (Glc)1 (GlcNAc)1 (LFuc)1 (Cer)1_C64H112N3O36FULLRCO

528341
type: SpeciesReference
stoichiometry: 1.0
species: 456641

528480
type: SpeciesReference
stoichiometry: 8.0
species: 458819

528454
type: SpeciesReference
stoichiometry: 1.0
species: 456342

456342
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: fucosyl galactosylgloboside (homo sapiens)_C56H99N2O31FULLRCO

528377
type: SpeciesReference
stoichiometry: 1.0
species: 456713

456713
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)4 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)1 (Cer)1_C78H135N4O46FULLRCO

528353
type: SpeciesReference
stoichiometry: 1.0
species: 456859

528540
type: SpeciesReference
stoichiometry: 1.0
species: 456233

528467
type: SpeciesReference
stoichiometry: 1.0
species: 456317

453578
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Deoxyguanosine_C10H13N5O4

989903
type: Reaction
is: http://identifiers.org/ec-code/3.1.1.3
product: 495887
product: 495911
is: ENSBTAG00000000765.4
notes: R_LPSe subsystem: Triacylglycerol Synthesis R_LPSe equation: [e] : h2o + tag_hs --> Rtotal3 + dag_hs + h
reactant: 495875
is: ENSBTAG00000032850.1
name: lipase
is: ENSBTAG00000032237.2
reactant: 495863
is: ENSBTAG00000006445.4
fast: false
product: 495899
reversible: false

495887
type: SpeciesReference
stoichiometry: 1.0
species: 458806

495911
type: SpeciesReference
stoichiometry: 1.0
species: 452963

452963
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2

495875
type: SpeciesReference
stoichiometry: 1.0
species: 458697

495863
type: SpeciesReference
stoichiometry: 1.0
species: 469310

495899
type: SpeciesReference
stoichiometry: 1.0
species: 447141

447141
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: R total 3 position_CO2FULLR3

992017
type: Reaction
fast: false
product: 515384
product: 515359
product: 515420
is: ENSBTAG00000013636.4
product: 515408
reactant: 515334
reactant: 515347
is: ENSBTAG00000019980.4
reversible: true
reactant: 515322
is: http://identifiers.org/ec-code/2.7.1.107
product: 515371
product: 515396
reactant: 515310
notes: R_DAGK_hs subsystem: Glycerophospholipid Metabolism R_DAGK_hs equation: [c] : atp + dag_hs <==> adp + h + pa_hs R_DAGKn_hs subsystem: Glycerophospholipid Metabolism R_DAGKn_hs equation: [n] : atp + dag_hs <==> adp + h + pa_hs

515384
type: SpeciesReference
stoichiometry: 1.0
species: 465840

515359
type: SpeciesReference
stoichiometry: 1.0
species: 465876

515420
type: SpeciesReference
stoichiometry: 1.0
species: 458794

515408
type: SpeciesReference
stoichiometry: 1.0
species: 448498

448498
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: ADP_C10H12N5O10P2

515334
type: SpeciesReference
stoichiometry: 1.0
species: 452975

515347
type: SpeciesReference
stoichiometry: 1.0
species: 450019

515322
type: SpeciesReference
stoichiometry: 1.0
species: 449983

515371
type: SpeciesReference
stoichiometry: 1.0
species: 458855

515396
type: SpeciesReference
stoichiometry: 1.0
species: 448462

515310
type: SpeciesReference
stoichiometry: 1.0
species: 452951

454294
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: DNA 5-methylcytosine_C11H19O8PR2

462465
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: lignoceric acid_C24H47O2

466298
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Procollagen 5-hydroxy-L-lysine_C6H14N2O3

995292
type: Reaction
reactant: 548149
product: 548197
product: 548185
reversible: false
reactant: 548137
fast: false
product: 548210
reactant: 548173
reactant: 548161
notes: R_P45039A1r subsystem: Bile Acid Biosynthesis R_P45039A1r equation: [r] : h + nadph + o2 + xol24oh --> h2o + nadp + xoltri24
name: oxysterol 7-alpha-hydroxylase
is: ENSBTAG00000003632.4

548149
type: SpeciesReference
stoichiometry: 1.0
species: 471444

548197
type: SpeciesReference
stoichiometry: 1.0
species: 464687

548185
type: SpeciesReference
stoichiometry: 1.0
species: 458758

548137
type: SpeciesReference
stoichiometry: 1.0
species: 465282

548210
type: SpeciesReference
stoichiometry: 1.0
species: 471673

548173
type: SpeciesReference
stoichiometry: 1.0
species: 458867

548161
type: SpeciesReference
stoichiometry: 1.0
species: 464747

447413
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Tn antigen_C8H14NO5X

989030
type: Reaction
reactant: 488469
reactant: 488445
product: 488481
product: 488493
is: http://identifiers.org/ec-code/2.4.99.8
notes: R_ST8SIA12 subsystem: Sphingolipid Metabolism R_ST8SIA12 equation: [g] : cmpacna + gm3_hs --> cmp + gd3_hs + h R_ST8SIA11 subsystem: Sphingolipid Metabolism R_ST8SIA11 equation: [g] : acngalgbside_hs + cmpacna --> acnacngalgbside_hs + cmp + h
reactant: 488457
fast: false
reversible: false
product: 488505
is: ENSBTAG00000000593.4
product: 488517

488469
type: SpeciesReference
stoichiometry: 1.0
species: 458058

488445
type: SpeciesReference
stoichiometry: 2.0
species: 451471

488481
type: SpeciesReference
stoichiometry: 2.0
species: 458819

488493
type: SpeciesReference
stoichiometry: 1.0
species: 448172

448172
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: disialyl galactosylgloboside (homo sapiens)_C72H121N4O43FULLRCO

488457
type: SpeciesReference
stoichiometry: 1.0
species: 448268

488505
type: SpeciesReference
stoichiometry: 2.0
species: 451422

488517
type: SpeciesReference
stoichiometry: 1.0
species: 457175

448316
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: O-Acetylcarnitine_C9H17NO4

469214
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Succinate_C4H4O4

996699
type: Reaction
fast: false
product: 560986
reversible: false
is: http://identifiers.org/ec-code/4.2.1.24
product: 560962
notes: R_PPBNGS subsystem: Heme Biosynthesis R_PPBNGS equation: [c] : (2) 5aop --> h + (2) h2o + ppbng
is: ENSBTAG00000000251.4
product: 560974
name: porphobilinogen synthase
reactant: 560950

560986
type: SpeciesReference
stoichiometry: 1.0
species: 458794

560962
type: SpeciesReference
stoichiometry: 1.0
species: 466952

466952
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Porphobilinogen_C10H13N2O4

560974
type: SpeciesReference
stoichiometry: 2.0
species: 458685

560950
type: SpeciesReference
stoichiometry: 2.0
species: 446070

446070
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-Amino-4-oxopentanoate_C5H9NO3

465270
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: O2_O2

470775
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658

988082
type: Reaction
name: pyrimidine-nucleoside phosphorylase (uracil)
product: 478955
is: http://identifiers.org/ec-code/2.4.2.2
is: ENSBTAG00000008428.4
fast: false
reversible: true
notes: R_PYNP2r subsystem: Pyrimidine Catabolism R_PYNP2r equation: [c] : pi + uri <==> r1p + ura
reactant: 478943
product: 478967
reactant: 478931

478955
type: SpeciesReference
stoichiometry: 1.0
species: 468018

478943
type: SpeciesReference
stoichiometry: 1.0
species: 471119

478967
type: SpeciesReference
stoichiometry: 1.0
species: 471035

478931
type: SpeciesReference
stoichiometry: 1.0
species: 466736

461516
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 34_C241H385N17O202S10X

993313
type: Reaction
reactant: 527314
product: 527350
is: http://identifiers.org/ec-code/3.1.3.56
reactant: 527338
notes: R_PI345P5P subsystem: Inositol Phosphate Metabolism R_PI345P5P equation: [c] : h2o + pail345p_hs --> pail34p_hs + pi R_MI145PP subsystem: Inositol Phosphate Metabolism R_MI145PP equation: [c] : h2o + mi145p --> mi14p + pi R_PI45P5P subsystem: Inositol Phosphate Metabolism R_PI45P5P equation: [c] : h2o + pail45p_hs --> pail4p_hs + pi R_MI1345PP subsystem: Inositol Phosphate Metabolism R_MI1345PP equation: [c] : h2o + mi1345p --> mi134p + pi
fast: false
product: 527362
is: ENSBTAG00000003063.4
product: 527374
product: 527386
is: ENSBTAG00000024107.3
is: http://identifiers.org/ec-code/3.1.3.36
is: ENSBTAG00000001354.4
reactant: 527326
reversible: false
reactant: 527302
reactant: 527290
product: 527398

527314
type: SpeciesReference
stoichiometry: 1.0
species: 463951

527350
type: SpeciesReference
stoichiometry: 1.0
species: 463987

527338
type: SpeciesReference
stoichiometry: 4.0
species: 458685

527362
type: SpeciesReference
stoichiometry: 4.0
species: 466736

527374
type: SpeciesReference
stoichiometry: 1.0
species: 466070

527386
type: SpeciesReference
stoichiometry: 1.0
species: 465973

527326
type: SpeciesReference
stoichiometry: 1.0
species: 464011

527302
type: SpeciesReference
stoichiometry: 1.0
species: 466046

527290
type: SpeciesReference
stoichiometry: 1.0
species: 465949

527398
type: SpeciesReference
stoichiometry: 1.0
species: 464035

994932
type: Reaction
fast: false
reactant: 545154
reactant: 545118
product: 545178
product: 545190
reversible: false
reactant: 545142
is: http://identifiers.org/ec-code/3.2.1.49
reactant: 545130
product: 545166
is: ENSBTAG00000021373.4
notes: R_NAGAly subsystem: Sphingolipid Metabolism R_NAGAly equation: [l] : acgagbside_hs + h + udp --> gbside_hs + udpacgal R_NAGA2ly subsystem: Keratan sulfate degradation R_NAGA2ly equation: [l] : Tn_antigen + h + udp --> Ser/Thr + udpacgal

545154
type: SpeciesReference
stoichiometry: 2.0
species: 470701

545118
type: SpeciesReference
stoichiometry: 2.0
species: 458831

545178
type: SpeciesReference
stoichiometry: 2.0
species: 470775

545190
type: SpeciesReference
stoichiometry: 1.0
species: 457018

457018
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: globoside (homo sapiens)_C44H79N2O22FULLRCO

545142
type: SpeciesReference
stoichiometry: 1.0
species: 447413

545130
type: SpeciesReference
stoichiometry: 1.0
species: 447822

545166
type: SpeciesReference
stoichiometry: 1.0
species: 447335

447335
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: protein-linked serine or threonine residue (O-glycosylation site)_XH

453048
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: dATP_C10H12N5O12P3

997757
type: Reaction
reactant: 572093
reactant: 572081
product: 572117
is: http://identifiers.org/ec-code/3.5.4.3
product: 572129
notes: R_GUAD subsystem: Purine Catabolism R_GUAD equation: [c] : gua + h + h2o --> nh4 + xan
reversible: false
fast: false
name: guanine deaminase
is: ENSBTAG00000011545.3
reactant: 572105

572093
type: SpeciesReference
stoichiometry: 1.0
species: 458685

572081
type: SpeciesReference
stoichiometry: 1.0
species: 458552

572117
type: SpeciesReference
stoichiometry: 1.0
species: 471408

471408
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Xanthine_C5H4N4O2

572129
type: SpeciesReference
stoichiometry: 1.0
species: 464834

572105
type: SpeciesReference
stoichiometry: 1.0
species: 458794

444201
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: _1-Pyrroline-2-carboxylate_C5H6NO2

993758
type: Reaction
product: 531220
is: http://identifiers.org/ec-code/2.6.1.39
is: ENSBTAG00000010326.4
fast: false
reactant: 531172
reversible: false
product: 531196
notes: R_3HKYNAKGAT subsystem: Tryptophan metabolism R_3HKYNAKGAT equation: [c] : akg + hLkynr --> 42A3HP24DB + glu-L R_KYNAKGAT subsystem: Tryptophan metabolism R_KYNAKGAT equation: [c] : Lkynr + akg --> 4aphdob + glu-L R_AATAi subsystem: Lysine Metabolism R_AATAi equation: [c] : L2aadp + akg --> 2oxoadp + glu-L
product: 531184
reactant: 531160
product: 531208
reactant: 531135
reactant: 531148
is: http://identifiers.org/ec-code/2.6.1.7

531220
type: SpeciesReference
stoichiometry: 1.0
species: 445432

531172
type: SpeciesReference
stoichiometry: 1.0
species: 446913

531196
type: SpeciesReference
stoichiometry: 1.0
species: 444575

531184
type: SpeciesReference
stoichiometry: 1.0
species: 445589

531160
type: SpeciesReference
stoichiometry: 1.0
species: 446816

446816
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-2-Aminoadipate_C6H10NO4

531208
type: SpeciesReference
stoichiometry: 3.0
species: 457525

531135
type: SpeciesReference
stoichiometry: 3.0
species: 448946

531148
type: SpeciesReference
stoichiometry: 1.0
species: 458782

989579
type: Reaction
reactant: 493494
fast: false
product: 493626
reactant: 493506
reactant: 493530
product: 493650
is: ENSBTAG00000018579.4
product: 493614
reactant: 493554
reactant: 493542
product: 493662
reactant: 493518
is: http://identifiers.org/ec-code/3.2.1.31
product: 493638
reversible: false
reactant: 493566
reactant: 493482
product: 493602
product: 493578
notes: R_GLCAASE1ly subsystem: Heparan sulfate degradation R_GLCAASE1ly equation: [l] : h2o + hs_deg9 --> glcur + hs_deg10 R_GLCAASE9ly subsystem: Hyaluronan Metabolism R_GLCAASE9ly equation: [l] : (2) h2o + ha_pre1 --> acgam + glcur R_GLCAASE5ly subsystem: Chondroitin sulfate degradation R_GLCAASE5ly equation: [l] : cs_c_deg2 + h2o --> cs_c_deg3 + glcur R_GLCAASE4ly subsystem: Chondroitin sulfate degradation R_GLCAASE4ly equation: [l] : cs_a_deg2 + h2o --> cs_a_deg3 + glcur R_GLCAASE6ly subsystem: Chondroitin sulfate degradation R_GLCAASE6ly equation: [l] : cs_d_deg3 + h2o --> cs_d_deg4 + glcur R_GLCAASE8ly subsystem: Hyaluronan Metabolism R_GLCAASE8ly equation: [l] : h2o + ha --> glcur + ha_deg1 R_GLCAASE7ly subsystem: Chondroitin sulfate degradation R_GLCAASE7ly equation: [l] : cs_e_deg3 + h2o --> cs_e_deg4 + glcur
product: 493590

493494
type: SpeciesReference
stoichiometry: 1.0
species: 458940

458940
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: hyaluronan biosynthesis, precursor 1_C14H20NO11

493626
type: SpeciesReference
stoichiometry: 7.0
species: 457452

457452
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: D-Glucuronate_C6H9O7

493506
type: SpeciesReference
stoichiometry: 1.0
species: 452335

493530
type: SpeciesReference
stoichiometry: 1.0
species: 458916

458916
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: hyaluronan_C28H40N2O22

493650
type: SpeciesReference
stoichiometry: 1.0
species: 447968

447968
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: N-Acetyl-D-glucosamine_C8H15NO6

493614
type: SpeciesReference
stoichiometry: 1.0
species: 459529

459529
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: heparan sulfate, degradation product 10_C55H80N3O70S8

493554
type: SpeciesReference
stoichiometry: 1.0
species: 452467

452467
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 3_C37H53NO44S4

493542
type: SpeciesReference
stoichiometry: 1.0
species: 459818

459818
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: heparan sulfate, degradation product 9_C61H87N3O76S8

493662
type: SpeciesReference
stoichiometry: 1.0
species: 458891

493518
type: SpeciesReference
stoichiometry: 8.0
species: 458721

493638
type: SpeciesReference
stoichiometry: 1.0
species: 452082

452082
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 3_C31H48NO32S2

493566
type: SpeciesReference
stoichiometry: 1.0
species: 452226

452226
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 2_C37H55NO38S2

493482
type: SpeciesReference
stoichiometry: 1.0
species: 452070

452070
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 2_C37H55NO38S2

493602
type: SpeciesReference
stoichiometry: 1.0
species: 452347

452347
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 4_C31H47NO35S3

493578
type: SpeciesReference
stoichiometry: 1.0
species: 452239

452239
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 3_C31H48NO32S2

493590
type: SpeciesReference
stoichiometry: 1.0
species: 452479

452479
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 4_C31H46NO38S4

992317
type: Reaction
product: 518809
product: 518821
reactant: 518772
product: 518784
fast: false
notes: R_SELt4_3 subsystem: Transport, Extracellular R_SELt4_3 equation: (3) na1[e] + sel[e] <==> (3) na1[c] + sel[c] R_SO4t4_3 subsystem: Transport, Extracellular R_SO4t4_3 equation: (3) na1[e] + so4[e] <==> (3) na1[c] + so4[c] R_TSULt4_3 subsystem: Transport, Extracellular R_TSULt4_3 equation: (3) na1[e] + tsul[e] <==> (3) na1[c] + tsul[c]
is: ENSBTAG00000006674.4
reactant: 518760
reactant: 518736
reactant: 518748
product: 518796
reversible: true

518809
type: SpeciesReference
stoichiometry: 9.0
species: 464458

518821
type: SpeciesReference
stoichiometry: 1.0
species: 468743

518772
type: SpeciesReference
stoichiometry: 1.0
species: 468515

468515
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Selenate_O4Se

518784
type: SpeciesReference
stoichiometry: 1.0
species: 470471

518760
type: SpeciesReference
stoichiometry: 1.0
species: 470483

470483
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Thiosulfate_O3S2

518736
type: SpeciesReference
stoichiometry: 9.0
species: 464470

518748
type: SpeciesReference
stoichiometry: 1.0
species: 468755

518796
type: SpeciesReference
stoichiometry: 1.0
species: 468503

468503
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Selenate_O4Se

988874
type: Reaction
product: 486756
reactant: 486707
product: 486780
is: http://identifiers.org/ec-code/3.5.1.26
is: ENSBTAG00000017085.2
reactant: 486744
fast: false
product: 486768
reactant: 486732
notes: R_GASNASE2ly subsystem: N-Glycan Degradation R_GASNASE2ly equation: [l] : h2o + n2m2nmasn --> Asn-X-Ser/Thr + n2m2nm R_GASNASE3ly subsystem: Keratan sulfate degradation R_GASNASE3ly equation: [l] : h2o + ksi_deg1 --> Asn-X-Ser/Thr + ksi_deg2 R_GASNASEly subsystem: N-Glycan Degradation R_GASNASEly equation: [l] : h2o + s2l2n2m2masn --> Asn-X-Ser/Thr + s2l2n2m2m
reversible: false
product: 486792
reactant: 486719

486756
type: SpeciesReference
stoichiometry: 1.0
species: 464350

464350
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: n2m2nmasn (w/o peptide linkage)_C58H97N5O41

486707
type: SpeciesReference
stoichiometry: 1.0
species: 464374

464374
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-(N-acetyl-beta-D-glucosaminyl-1,4)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R_C58H96N5O40X

486780
type: SpeciesReference
stoichiometry: 1.0
species: 460923

486744
type: SpeciesReference
stoichiometry: 1.0
species: 460788

460788
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 1_C241H383N17O209S12X

486768
type: SpeciesReference
stoichiometry: 3.0
species: 446780

446780
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: protein-linked asparagine residue (N-glycosylation site)_XH

486732
type: SpeciesReference
stoichiometry: 3.0
species: 458721

486792
type: SpeciesReference
stoichiometry: 1.0
species: 468297

468297
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: de-Fuc form of PA6 (w/o peptide linkage)_C84H136N6O62

486719
type: SpeciesReference
stoichiometry: 1.0
species: 468321

468321
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: de-Fuc form of PA6_C84H135N6O61X

450067
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Crotonoyl-CoA_C25H36N7O17P3S

453324
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: trans-Dodec-2-enoyl-CoA_C33H52N7O17P3S

997031
type: Reaction
product: 564242
is: ENSBTAG00000009172.3
reversible: true
is: http://identifiers.org/ec-code/2.6.1.6
reactant: 564194
product: 564230
reactant: 564206
reactant: 564182
notes: R_VALTAm subsystem: Valine, Leucine, and Isoleucine Metabolism R_VALTAm equation: [m] : akg + val-L <==> 3mob + glu-L R_ILETAm subsystem: Valine, Leucine, and Isoleucine Metabolism R_ILETAm equation: [m] : akg + ile-L <==> 3mop + glu-L R_LEUTAm subsystem: Valine, Leucine, and Isoleucine Metabolism R_LEUTAm equation: [m] : akg + leu-L <==> 4mop + glu-L
product: 564266
reactant: 564218
is: http://identifiers.org/ec-code/2.6.1.42
fast: false
product: 564254

564242
type: SpeciesReference
stoichiometry: 1.0
species: 445167

564194
type: SpeciesReference
stoichiometry: 1.0
species: 462344

462344
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Leucine_C6H13NO2

564230
type: SpeciesReference
stoichiometry: 1.0
species: 445757

564206
type: SpeciesReference
stoichiometry: 1.0
species: 471311

564182
type: SpeciesReference
stoichiometry: 3.0
species: 448970

564266
type: SpeciesReference
stoichiometry: 1.0
species: 445191

564218
type: SpeciesReference
stoichiometry: 1.0
species: 460315

564254
type: SpeciesReference
stoichiometry: 3.0
species: 457562

990084
type: Reaction
product: 497222
product: 497258
reactant: 497186
product: 497246
is: ENSBTAG00000020546.4
reversible: false
is: http://identifiers.org/ec-code/2.1.1.37
reactant: 497210
is: ENSBTAG00000031184.2
fast: false
product: 497234
reactant: 497198
is: ENSBTAG00000021143.4
is: ENSBTAG00000003901.4
notes: R_DNAMTSEn subsystem: Selenoamino acid metabolism R_DNAMTSEn equation: [n] : dna + seasmet --> dna5mtc + h + seahcys R_DNAMTn subsystem: Methionine Metabolism R_DNAMTn equation: [n] : amet + dna --> ahcys + dna5mtc + h

497222
type: SpeciesReference
stoichiometry: 2.0
species: 454294

497258
type: SpeciesReference
stoichiometry: 1.0
species: 448837

448837
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

497186
type: SpeciesReference
stoichiometry: 2.0
species: 454306

454306
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: DNA_C10H17O8PR2

497246
type: SpeciesReference
stoichiometry: 1.0
species: 468467

468467
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Se-Adenosylselenohomocysteine_C14H20N6O5Se

497210
type: SpeciesReference
stoichiometry: 1.0
species: 468491

468491
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Se-Adenosylselenomethionine_C15H23N6O5Se

497234
type: SpeciesReference
stoichiometry: 2.0
species: 458855

497198
type: SpeciesReference
stoichiometry: 1.0
species: 449260

449260
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: S-Adenosyl-L-methionine_C15H23N6O5S

453977
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: dIDP_C10H11N4O10P2

ORG:
  orgname: University of Missouri
n:
  given: Michaël
  family: Bekaert

997419
type: Reaction
product: 568750
product: 568786
product: 568738
reactant: 568665
product: 568762
fast: false
reactant: 568714
product: 568726
reactant: 568690
is: ENSBTAG00000014371.3
notes: R_GLCAT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT5g equation: [g] : cs_e_pre2 + udpglcur --> cs_e_pre3 + h + udp R_GLCAT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT3g equation: [g] : cs_c,d,e_pre1 + udpglcur --> cs_c_pre2 + h + udp R_GLCAT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT4g equation: [g] : cs_d_pre2 + udpglcur --> cs_d_pre3 + h + udp R_GLCAT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT2g equation: [g] : cs_a,b,e_pre1 + udpglcur --> cs_a,b_pre2 + h + udp
reactant: 568702
reversible: false
product: 568774
reactant: 568677

568750
type: SpeciesReference
stoichiometry: 4.0
species: 470688

568786
type: SpeciesReference
stoichiometry: 1.0
species: 452033

568738
type: SpeciesReference
stoichiometry: 1.0
species: 452287

568665
type: SpeciesReference
stoichiometry: 1.0
species: 452202

452202
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate C (GalNAc6S-GlcA) and D (GlcNAc6S-GlcA2S), precursor 1_C31H47NO31S2X

568762
type: SpeciesReference
stoichiometry: 4.0
species: 458819

568714
type: SpeciesReference
stoichiometry: 1.0
species: 452539

568726
type: SpeciesReference
stoichiometry: 1.0
species: 452407

568690
type: SpeciesReference
stoichiometry: 1.0
species: 452395

452395
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate D (GlcNAc6S-GlcA2S) precursor 2_C31H46NO34S3X

568702
type: SpeciesReference
stoichiometry: 4.0
species: 470872

568774
type: SpeciesReference
stoichiometry: 1.0
species: 452551

568677
type: SpeciesReference
stoichiometry: 1.0
species: 452021

464506
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Nicotinate_C6H4NO2

468803
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Sphinganine 1-phosphate_C18H39NO5P

464846
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Ammonium_H4N

470167
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: timnodonic acid C20:5, n-3_C20H29O2

455642
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

450152
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Bilirubin beta-diglucuronide_C45H50N4O18

990636
type: Reaction
fast: false
product: 501820
is: ENSBTAG00000026290.3
reactant: 501808
notes: R_PIK3 subsystem: Inositol Phosphate Metabolism R_PIK3 equation: [c] : atp + pail_hs --> adp + h + pail3p_hs R_PI5P3K subsystem: Inositol Phosphate Metabolism R_PI5P3K equation: [c] : atp + pail5p_hs --> adp + h + pail35p_hs
reversible: false
reactant: 501784
product: 501857
product: 501832
reactant: 501796
is: http://identifiers.org/ec-code/2.7.1.137
product: 501845

501820
type: SpeciesReference
stoichiometry: 1.0
species: 465998

501808
type: SpeciesReference
stoichiometry: 1.0
species: 466130

501784
type: SpeciesReference
stoichiometry: 1.0
species: 466106

501857
type: SpeciesReference
stoichiometry: 2.0
species: 458794

501832
type: SpeciesReference
stoichiometry: 2.0
species: 448462

501796
type: SpeciesReference
stoichiometry: 2.0
species: 449983

501845
type: SpeciesReference
stoichiometry: 1.0
species: 466022

468911
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO

460727
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 16_C160H258N11O137S7

459842
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: heparan sulfate, precursor 10_C79H121N5O77S4X

466687
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: phytanic acid_C20H39O2

461262
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 15_C149H240N10O119S4X

469371
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: paclitaxel_C47H31NO14

455124
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Elaidic carnitine_C25H47NO4

991644
type: Reaction
reactant: 511319
is: ENSBTAG00000017595.4
product: 511367
reversible: false
fast: false
reactant: 511331
notes: R_S2T4g subsystem: Chondroitin / heparan sulfate biosynthesis R_S2T4g equation: [g] : hs_pre11 + (2) paps --> (2) h + hs_pre12 + (2) pap
product: 511355
name: uronyl 2-sulfotransferase, Golgi
product: 511343

511319
type: SpeciesReference
stoichiometry: 1.0
species: 459854

511367
type: SpeciesReference
stoichiometry: 1.0
species: 459866

511331
type: SpeciesReference
stoichiometry: 2.0
species: 466226

511355
type: SpeciesReference
stoichiometry: 2.0
species: 466202

511343
type: SpeciesReference
stoichiometry: 2.0
species: 458819

994487
type: Reaction
notes: R_A_MANASEly subsystem: N-Glycan Degradation R_A_MANASEly equation: [l] : (2) h2o + m2mn --> (2) man + mn
is: http://identifiers.org/ec-code/3.2.1.24
reversible: false
is: ENSBTAG00000006241.4
reactant: 540205
name: alpha-mannosidase, lysosomal
product: 540230
fast: false
reactant: 540193
product: 540217

540205
type: SpeciesReference
stoichiometry: 1.0
species: 463045

463045
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: (alpha-D-mannosyl)2-beta-D-mannosyl-N-acetylglucosamine_C26H45NO21

540230
type: SpeciesReference
stoichiometry: 1.0
species: 464242

464242
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: beta-1,4-mannose-N-acetylglucosamine_C14H25NO11

540193
type: SpeciesReference
stoichiometry: 2.0
species: 458721

540217
type: SpeciesReference
stoichiometry: 2.0
species: 463636

463636
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: D-Mannose_C6H12O6

988202
type: Reaction
reactant: 480593
fast: false
reversible: true
is: ENSBTAG00000021535.4
reactant: 480606
notes: R_CSNAT2x subsystem: Fatty Acid Metabolism R_CSNAT2x equation: [x] : crn + dmnoncoa <==> coa + dmnoncrn
name: carnitine dimethyl nonanoyl transferase, revsible, peroxisomal
product: 480618
product: 480630
is: http://identifiers.org/ec-code/2.3.1.7

480593
type: SpeciesReference
stoichiometry: 1.0
species: 454246

480606
type: SpeciesReference
stoichiometry: 1.0
species: 451937

451937
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: L-Carnitine_C7H15NO3

480618
type: SpeciesReference
stoichiometry: 1.0
species: 451671

480630
type: SpeciesReference
stoichiometry: 1.0
species: 454258

454258
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: _4,8 dimethylnonanoyl carnitine_C18H37NO4

992341
type: Reaction
reversible: true
notes: R_OCOAT1m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OCOAT1m equation: [m] : acac + succoa <==> aacoa + succ
is: ENSBTAG00000030376.2
product: 518953
reactant: 518929
fast: false
name: _3-oxoacid CoA-transferase
reactant: 518917
is: http://identifiers.org/ec-code/2.8.3.5
is: ENSBTAG00000018933.3
product: 518941
is: ENSBTAG00000033186.2

518953
type: SpeciesReference
stoichiometry: 1.0
species: 469190

518929
type: SpeciesReference
stoichiometry: 1.0
species: 447593

518917
type: SpeciesReference
stoichiometry: 1.0
species: 469226

518941
type: SpeciesReference
stoichiometry: 1.0
species: 447461

468273
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: PA6_C90H145N6O65X

462368
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Leukotriene A4_C20H29O3

988562
type: Reaction
product: 483679
reactant: 483383
reactant: 483468
product: 483552
reactant: 483420
product: 483739
reactant: 483371
reactant: 483456
product: 483873
product: 483837
reactant: 483359
reversible: false
reactant: 483141
product: 483921
reactant: 483311
reactant: 483275
reactant: 483191
product: 483727
product: 483528
reactant: 483516
reactant: 483492
reactant: 483178
reactant: 483407
product: 483590
reactant: 483504
product: 483813
reactant: 483395
reactant: 483215
reactant: 483444
product: 483909
reactant: 483165
reactant: 483203
reactant: 483432
product: 483703
reactant: 483153
product: 483655
reactant: 483299
is: ENSBTAG00000014649.2
product: 483933
product: 483691
reactant: 483287
product: 483777
product: 483667
reactant: 483251
reactant: 483239
product: 483861
reactant: 483227
product: 483564
reactant: 483323
product: 483764
product: 483540
notes: R_HEXCCPT2 subsystem: Carnitine shuttle R_HEXCCPT2 equation: [m] : coa + hexccrn --> crn + hexccoa R_C181CPT2 subsystem: Carnitine shuttle R_C181CPT2 equation: [m] : coa + odecrn --> crn + odecoa R_C160CPT2 subsystem: Carnitine shuttle R_C160CPT2 equation: [m] : coa + pmtcrn --> crn + pmtcoa R_RTOTALCRNCPT2 subsystem: Carnitine shuttle R_RTOTALCRNCPT2 equation: [m] : Rtotalcrn + coa --> Rtotalcoa + crn R_RTOTAL2CRNCPT2 subsystem: Carnitine shuttle R_RTOTAL2CRNCPT2 equation: [m] : Rtotal2crn + coa --> Rtotal2coa + crn R_VACCCPT2 subsystem: Carnitine shuttle R_VACCCPT2 equation: [m] : coa + vacccrn --> crn + vacccoa R_EICOSTETCPT2 subsystem: Carnitine shuttle R_EICOSTETCPT2 equation: [m] : coa + eicostetcrn --> crn + eicostetcoa R_TTDCPT2 subsystem: Carnitine shuttle R_TTDCPT2 equation: [m] : coa + ttdcrn --> crn + tdcoa R_PTDCACRNCPT2 subsystem: Carnitine shuttle R_PTDCACRNCPT2 equation: [m] : coa + ptdcacrn --> crn + ptdcacoa R_LGNCCPT2 subsystem: Carnitine shuttle R_LGNCCPT2 equation: [m] : coa + lgnccrn --> crn + lgnccoa R_C226CPT2 subsystem: Carnitine shuttle R_C226CPT2 equation: [m] : c226crn + coa --> c226coa + crn R_C161CPT22 subsystem: Carnitine shuttle R_C161CPT22 equation: [m] : coa + hdd2crn --> crn + hdd2coa R_DLNLCGCPT2 subsystem: Carnitine shuttle R_DLNLCGCPT2 equation: [m] : coa + dlnlcgcrn --> crn + dlnlcgcoa R_LNLCCPT2 subsystem: Carnitine shuttle R_LNLCCPT2 equation: [m] : coa + lnlccrn --> crn + lnlccoa R_CLPNDCPT2 subsystem: Carnitine shuttle R_CLPNDCPT2 equation: [m] : clpndcrn + coa --> clpndcoa + crn R_DCSPTN1CPT2 subsystem: Carnitine shuttle R_DCSPTN1CPT2 equation: [m] : coa + dcsptn1crn --> crn + dcsptn1coa R_HPDCACRNCPT2 subsystem: Carnitine shuttle R_HPDCACRNCPT2 equation: [m] : coa + hpdcacrn --> crn + hpdcacoa R_LNELDCCPT2 subsystem: Carnitine shuttle R_LNELDCCPT2 equation: [m] : coa + lneldccrn --> crn + lneldccoa R_STRDNCCPT2 subsystem: Carnitine shuttle R_STRDNCCPT2 equation: [m] : coa + strdnccrn --> crn + strdnccoa R_NRVNCCPT2 subsys…
reactant: 483129
product: 483751
reactant: 483117
product: 483825
product: 483629
reactant: 483263
product: 483603
product: 483885
product: 483715
product: 483616
reactant: 483347
product: 483897
product: 483577
product: 483801
reactant: 483335
product: 483642
product: 483849
fast: false
reactant: 483480
product: 483789

483679
type: SpeciesReference
stoichiometry: 1.0
species: 450467

483383
type: SpeciesReference
stoichiometry: 1.0
species: 449777

449777
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: C20:4 carnitine_C27H45NO4

483468
type: SpeciesReference
stoichiometry: 1.0
species: 454160

483552
type: SpeciesReference
stoichiometry: 1.0
species: 465609

483420
type: SpeciesReference
stoichiometry: 1.0
species: 453240

453240
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: docosa-4,7,10,13,16-pentaenoyl carnitine_C29H47NO4

483739
type: SpeciesReference
stoichiometry: 1.0
species: 459229

459229
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Hexacosanoyl-CoA (n-C26:0CoA)_C47H82N7O17P3S

483371
type: SpeciesReference
stoichiometry: 1.0
species: 467777

467777
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: pendtadenoyl carnitine_C22H43NO4

483456
type: SpeciesReference
stoichiometry: 1.0
species: 465670

483873
type: SpeciesReference
stoichiometry: 1.0
species: 447093

447093
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: R total 2 coenzyme A_CO2FULLR2C21H31N7O15P3S

483837
type: SpeciesReference
stoichiometry: 1.0
species: 459469

459469
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: heptadecanoyl coa_C38H64N7O17P3S

483359
type: SpeciesReference
stoichiometry: 1.0
species: 470555

470555
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: tetradecanoyl carnitine_C21H41NO4

483141
type: SpeciesReference
stoichiometry: 1.0
species: 462659

462659
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Linoelaidyl carnitine_C25H45NO4

483921
type: SpeciesReference
stoichiometry: 1.0
species: 469637

469637
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: tetracosapentaenoyl coenzyme A, n-6_C45H68N7O17P3S

483311
type: SpeciesReference
stoichiometry: 1.0
species: 466880

466880
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Palmitoylcarnitine_C23H45NO4

483275
type: SpeciesReference
stoichiometry: 1.0
species: 465198

465198
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Nervonyl carnitine_C31H59NO4

483191
type: SpeciesReference
stoichiometry: 1.0
species: 455136

483727
type: SpeciesReference
stoichiometry: 1.0
species: 459133

483528
type: SpeciesReference
stoichiometry: 1.0
species: 469020

483516
type: SpeciesReference
stoichiometry: 1.0
species: 459169

459169
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: trans-Hexadec-2-enoyl carnitine_C23H43NO4

483492
type: SpeciesReference
stoichiometry: 1.0
species: 462719

462719
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Linoleyl carnitine_C25H45NO4

483178
type: SpeciesReference
stoichiometry: 1.0
species: 447117

483407
type: SpeciesReference
stoichiometry: 1.0
species: 447189

483590
type: SpeciesReference
stoichiometry: 1.0
species: 459109

483504
type: SpeciesReference
stoichiometry: 1.0
species: 471275

471275
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Vaccenyl carnitine_C25H47NO4

483813
type: SpeciesReference
stoichiometry: 1.0
species: 447165

447165
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: R total 3 Coenzyme A_CO2FULLR3C21H31N7O15P3S

483395
type: SpeciesReference
stoichiometry: 33.0
species: 451632

483215
type: SpeciesReference
stoichiometry: 1.0
species: 450503

483444
type: SpeciesReference
stoichiometry: 1.0
species: 469673

469673
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: tetracosapentaenoyl carnitine_C31H51NO4

483909
type: SpeciesReference
stoichiometry: 33.0
species: 451913

483165
type: SpeciesReference
stoichiometry: 1.0
species: 462851

462851
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: gamma-linolenyl carnitine_C25H43NO4

483203
type: SpeciesReference
stoichiometry: 1.0
species: 469056

483432
type: SpeciesReference
stoichiometry: 1.0
species: 462779

483703
type: SpeciesReference
stoichiometry: 1.0
species: 462755

483153
type: SpeciesReference
stoichiometry: 1.0
species: 470228

470228
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Timnodonyl carnitine_C27H43NO4

483655
type: SpeciesReference
stoichiometry: 1.0
species: 469564

483299
type: SpeciesReference
stoichiometry: 1.0
species: 455100

455100
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Eicosatetranoyl carnitine_C27H45NO4

483933
type: SpeciesReference
stoichiometry: 1.0
species: 451338

451338
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: clupanodonyl CoA_C43H64N7O17P3S

483691
type: SpeciesReference
stoichiometry: 1.0
species: 462501

462501
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: lignocericyl coenzyme A_C45H78N7O17P3S

483287
type: SpeciesReference
stoichiometry: 1.0
species: 448693

448693
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Adrenyl carnitine_C29H49NO4

483777
type: SpeciesReference
stoichiometry: 1.0
species: 469709

469709
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: tetracosatetraenoyl coenzyme A_C45H70N7O17P3S

483667
type: SpeciesReference
stoichiometry: 1.0
species: 465162

465162
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: nervonyl coenzyme A_C45H76N7O17P3S

483251
type: SpeciesReference
stoichiometry: 1.0
species: 459265

459265
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: hexacosanoyl carnitine_C33H65NO4

483239
type: SpeciesReference
stoichiometry: 1.0
species: 459493

459493
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: heptadecanoyl carnitine_C24H47NO4

483861
type: SpeciesReference
stoichiometry: 1.0
species: 469467

483227
type: SpeciesReference
stoichiometry: 1.0
species: 459085

459085
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Hexadecenoyl carnitine_C23H43NO4

483564
type: SpeciesReference
stoichiometry: 1.0
species: 466844

483323
type: SpeciesReference
stoichiometry: 1.0
species: 469154

469154
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: stearidonyl carnitine_C25H41NO4

483764
type: SpeciesReference
stoichiometry: 1.0
species: 470192

483540
type: SpeciesReference
stoichiometry: 1.0
species: 449741

483129
type: SpeciesReference
stoichiometry: 1.0
species: 449681

483751
type: SpeciesReference
stoichiometry: 1.0
species: 462635

483117
type: SpeciesReference
stoichiometry: 1.0
species: 447298

447298
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: R total carnitine_CO2FULLRC7H14NO2

483825
type: SpeciesReference
stoichiometry: 1.0
species: 462695

483629
type: SpeciesReference
stoichiometry: 1.0
species: 449645

483263
type: SpeciesReference
stoichiometry: 1.0
species: 451374

451374
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: clupanodonyl carnitine_C29H47NO4

483603
type: SpeciesReference
stoichiometry: 1.0
species: 469116

483885
type: SpeciesReference
stoichiometry: 1.0
species: 453204

483715
type: SpeciesReference
stoichiometry: 1.0
species: 465633

483616
type: SpeciesReference
stoichiometry: 1.0
species: 455076

483347
type: SpeciesReference
stoichiometry: 1.0
species: 462538

462538
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: lignoceryl carnitine_C31H61NO4

483897
type: SpeciesReference
stoichiometry: 1.0
species: 462815

483577
type: SpeciesReference
stoichiometry: 1.0
species: 454136

483801
type: SpeciesReference
stoichiometry: 1.0
species: 467753

483335
type: SpeciesReference
stoichiometry: 1.0
species: 469600

469600
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: tetracosapentaenoyl carnitine_C31H51NO4

483642
type: SpeciesReference
stoichiometry: 1.0
species: 448657

483849
type: SpeciesReference
stoichiometry: 1.0
species: 447262

447262
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: R total Coenzyme A_CO2FULLRC21H31N7O15P3S

483480
type: SpeciesReference
stoichiometry: 1.0
species: 469745

469745
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Tetracosatetraenoyl carnitine_C31H53NO4

483789
type: SpeciesReference
stoichiometry: 1.0
species: 471251

450238
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Bilirubin_C33H34N4O6

446973
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Histone N6-methyl-L-lysine_CXH4

987673
type: Reaction
is: ENSBTAG00000000730.2
product: 475648
reactant: 475624
fast: false
product: 475660
product: 475672
notes: R_MDHm subsystem: Citric Acid Cycle R_MDHm equation: [m] : mal-L + nad <==> h + nadh + oaa R_SLDxm subsystem: Cysteine Metabolism R_SLDxm equation: [m] : nad + sl-L <==> 3spyr + h + nadh
is: http://identifiers.org/ec-code/1.1.1.272
product: 475636
reactant: 475600
reactant: 475612
reversible: true
is: http://identifiers.org/ec-code/1.1.1.37

475648
type: SpeciesReference
stoichiometry: 1.0
species: 465379

465379
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Oxaloacetate_C4H2O5

475624
type: SpeciesReference
stoichiometry: 1.0
species: 463455

475660
type: SpeciesReference
stoichiometry: 2.0
species: 458843

475672
type: SpeciesReference
stoichiometry: 2.0
species: 464602

475636
type: SpeciesReference
stoichiometry: 1.0
species: 445408

445408
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _3-Sulfopyruvate_C3H2O6S

475600
type: SpeciesReference
stoichiometry: 1.0
species: 468707

468707
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-sulfolactate_C3H4O6S

475612
type: SpeciesReference
stoichiometry: 2.0
species: 464542

470240
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: tolbutamide_C12H18N2O3S

460389
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: IMP_C10H11N4O8P

456463
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: (alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C82H137N2O65X

453372
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Dodecanoyl-CoA (n-C12:0CoA)_C33H54N7O17P3S

450323
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Biotinyl-5'-AMP_C20H27N7O9PS

995904
type: Reaction
modifier: 553195
modifier: 553231
fast: false
product: 553183
modifier: 553207
modifier: 553219
reversible: false
is: ENSBTAG00000021325.4
reactant: 553159
reactant: 553147
notes: R_THMt3 subsystem: Transport, Extracellular R_THMt3 equation: h[c] + thm[e] <==> h[e] + thm[c] R_BTNt4i subsystem: Transport, Extracellular R_BTNt4i equation: btn[e] + h[c] --> btn[c] + h[e]
product: 553171

553183
type: SpeciesReference
stoichiometry: 1.0
species: 450359

450359
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Biotin_C10H15N2O3S

553159
type: SpeciesReference
stoichiometry: 1.0
species: 458794

553147
type: SpeciesReference
stoichiometry: 1.0
species: 450371

450371
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Biotin_C10H15N2O3S

553171
type: SpeciesReference
stoichiometry: 1.0
species: 458806

444033
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _13-cis-retinoyl glucuronide_C26H35O8

994788
type: Reaction
is: ENSBTAG00000014093.3
product: 543927
product: 543903
notes: R_ICDHyrm subsystem: Citric Acid Cycle R_ICDHyrm equation: [m] : icit + nadp <==> akg + co2 + nadph
fast: false
name: Isocitrate dehydrogenase (NADP+)
reactant: 543891
reversible: true
product: 543915
is: http://identifiers.org/ec-code/1.1.1.42
reactant: 543878

543927
type: SpeciesReference
stoichiometry: 1.0
species: 464723

543903
type: SpeciesReference
stoichiometry: 1.0
species: 451545

543891
type: SpeciesReference
stoichiometry: 1.0
species: 464663

543915
type: SpeciesReference
stoichiometry: 1.0
species: 448970

543878
type: SpeciesReference
stoichiometry: 1.0
species: 460169

460169
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Isocitrate_C6H5O7

450744
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: CDP_C9H12N3O11P2

997808
type: Reaction
reactant: 572466
product: 572490
product: 572575
product: 572562
reactant: 572406
reactant: 572358
is: ENSBTAG00000033679.2
reactant: 572418
product: 572587
product: 572514
reactant: 572442
reactant: 572430
product: 572538
product: 572478
reactant: 572370
is: ENSBTAG00000008311.4
reactant: 572454
product: 572502
reactant: 572394
reactant: 572382
product: 572550
fast: false
is: http://identifiers.org/ec-code/6.3.4.15
product: 572526
reversible: false
notes: R_BACCL subsystem: Biotin Metabolism R_BACCL equation: [c] : atp + btn + h --> btamp + ppi R_BTNPLm subsystem: Biotin Metabolism R_BTNPLm equation: [m] : apoC-Lys + btamp --> amp + apoC-Lys_btn + h R_BTNPL subsystem: Biotin Metabolism R_BTNPL equation: [c] : apoC-Lys + btamp --> amp + apoC-Lys_btn + h R_BACCLm subsystem: Biotin Metabolism R_BACCLm equation: [m] : atp + btn + h --> btamp + ppi

572466
type: SpeciesReference
stoichiometry: 1.0
species: 449537

449537
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Apocarboxylase (Lys residue)_C6H13N2OX

572490
type: SpeciesReference
stoichiometry: 1.0
species: 449501

449501
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Holocarboxylase (biotin covalent bound to Lys residue of apoC)_C16H27N4O3SX

572575
type: SpeciesReference
stoichiometry: 1.0
species: 458843

572562
type: SpeciesReference
stoichiometry: 1.0
species: 458794

572406
type: SpeciesReference
stoichiometry: 1.0
species: 450359

572358
type: SpeciesReference
stoichiometry: 1.0
species: 449525

449525
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Apocarboxylase (Lys residue)_C6H13N2OX

572418
type: SpeciesReference
stoichiometry: 1.0
species: 450007

572587
type: SpeciesReference
stoichiometry: 1.0
species: 467000

572514
type: SpeciesReference
stoichiometry: 1.0
species: 449513

572442
type: SpeciesReference
stoichiometry: 1.0
species: 458843

572430
type: SpeciesReference
stoichiometry: 1.0
species: 450323

572538
type: SpeciesReference
stoichiometry: 1.0
species: 449296

572478
type: SpeciesReference
stoichiometry: 1.0
species: 449344

572370
type: SpeciesReference
stoichiometry: 1.0
species: 449983

572454
type: SpeciesReference
stoichiometry: 1.0
species: 458794

572502
type: SpeciesReference
stoichiometry: 1.0
species: 450335

450335
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Biotinyl-5'-AMP_C20H27N7O9PS

572394
type: SpeciesReference
stoichiometry: 1.0
species: 450335

572382
type: SpeciesReference
stoichiometry: 1.0
species: 450383

572550
type: SpeciesReference
stoichiometry: 1.0
species: 450323

572526
type: SpeciesReference
stoichiometry: 1.0
species: 467012

455196
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: phosphoethanolaminyl-mannosyl-glucosylaminyl-acylphosphatidylinositol (H5)_C39H74N2O22P2FULLRCO2FULLR2CO2

993470
type: Reaction
reactant: 528552
reactant: 528564
product: 528648
product: 528696
product: 528672
reversible: false
is: ENSBTAG00000000605.3
reactant: 528612
is: http://identifiers.org/ec-code/3.6.3.14
notes: R_CAT2p subsystem: Glycolysis/Gluconeogenesis R_CAT2p equation: [x] : etoh + h2o2 --> acald + (2) h2o R_ATPS4m subsystem: Oxidative Phosphorylation R_ATPS4m equation: adp[m] + (4) h[c] + pi[m] --> atp[m] + (3) h[m] + h2o[m] R_CATm subsystem: ROS Detoxification R_CATm equation: [m] : (2) h2o2 --> (2) h2o + o2 R_CATp subsystem: Miscellaneous R_CATp equation: [x] : (2) h2o2 --> (2) h2o + o2
product: 528684
fast: false
product: 528636
product: 528624
reactant: 528600
reactant: 528588
reactant: 528576
product: 528660
is: http://identifiers.org/ec-code/1.11.1.6

528552
type: SpeciesReference
stoichiometry: 1.0
species: 466784

528564
type: SpeciesReference
stoichiometry: 1.0
species: 448486

528648
type: SpeciesReference
stoichiometry: 3.0
species: 458733

528696
type: SpeciesReference
stoichiometry: 3.0
species: 458843

528672
type: SpeciesReference
stoichiometry: 1.0
species: 450007

528612
type: SpeciesReference
stoichiometry: 4.0
species: 458794

528684
type: SpeciesReference
stoichiometry: 1.0
species: 465258

528636
type: SpeciesReference
stoichiometry: 1.0
species: 465294

528624
type: SpeciesReference
stoichiometry: 4.0
species: 458770

528600
type: SpeciesReference
stoichiometry: 1.0
species: 455484

455484
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Ethanol_C2H6O

528588
type: SpeciesReference
stoichiometry: 2.0
species: 458649

528576
type: SpeciesReference
stoichiometry: 3.0
species: 458673

528660
type: SpeciesReference
stoichiometry: 1.0
species: 447653

447653
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Acetaldehyde_C2H4O

445311
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610

462767
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: alpha-linolenyl carnitine_C25H43NO4

996735
type: Reaction
product: 561227
product: 561203
notes: R_PTRCAT1 subsystem: Arginine and Proline Metabolism R_PTRCAT1 equation: [c] : accoa + ptrc --> aprut + coa + h
is: http://identifiers.org/ec-code/2.3.1.57
product: 561215
is: ENSBTAG00000013077.4
is: ENSBTAG00000017363.2
reversible: false
reactant: 561191
fast: false
is: ENSBTAG00000004222.3
name: Putrescine acetyltransferase
reactant: 561179

561227
type: SpeciesReference
stoichiometry: 1.0
species: 449573

561203
type: SpeciesReference
stoichiometry: 1.0
species: 451593

561215
type: SpeciesReference
stoichiometry: 1.0
species: 458794

561191
type: SpeciesReference
stoichiometry: 1.0
species: 467789

561179
type: SpeciesReference
stoichiometry: 1.0
species: 447665

462306
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Lactose_C12H22O11

997744
type: Reaction
reactant: 571984
product: 572033
reactant: 572008
is: http://identifiers.org/ec-code/2.7.1.127
product: 572045
product: 572057
reactant: 571960
reactant: 571972
is: http://identifiers.org/ec-code/2.7.1.151
reversible: false
notes: R_MI145P6Kn subsystem: Inositol Phosphate Metabolism R_MI145P6Kn equation: [n] : atp + mi145p --> adp + h + mi1456p R_MI1456PKn subsystem: Inositol Phosphate Metabolism R_MI1456PKn equation: [n] : atp + mi1456p --> adp + h + mi13456p R_MI1346PKn subsystem: Inositol Phosphate Metabolism R_MI1346PKn equation: [n] : atp + mi1346p --> adp + h + mi13456p R_MI1345PKn subsystem: Inositol Phosphate Metabolism R_MI1345PKn equation: [n] : atp + mi1345p --> adp + h + mi13456p R_MI145PKn subsystem: Inositol Phosphate Metabolism R_MI145PKn equation: [n] : atp + mi145p --> adp + h + mi1345p
product: 572069
is: http://identifiers.org/ec-code/2.7.1.140
reactant: 571996
product: 572021
fast: false
is: ENSBTAG00000011197.4

571984
type: SpeciesReference
stoichiometry: 1.0
species: 463963

463963
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: _1D-myo-Inositol 1,3,4,5-tetrakisphosphate_C6H8O18P4

572033
type: SpeciesReference
stoichiometry: 1.0
species: 463963

572008
type: SpeciesReference
stoichiometry: 5.0
species: 450019

572045
type: SpeciesReference
stoichiometry: 5.0
species: 458855

572057
type: SpeciesReference
stoichiometry: 3.0
species: 463939

463939
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: _1D-myo-Inositol 1,3,4,5,6-pentakisphosphate_C6H7O21P5

571960
type: SpeciesReference
stoichiometry: 1.0
species: 463999

463999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: _1D-myo-Inositol 1,4,5,6-tetrakisphosphate_C6H8O18P4

571972
type: SpeciesReference
stoichiometry: 1.0
species: 463975

463975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: _1D-myo-Inositol 1,3,4,6-tetrakisphosphate_C6H8O18P4

572069
type: SpeciesReference
stoichiometry: 5.0
species: 448498

571996
type: SpeciesReference
stoichiometry: 2.0
species: 464023

572021
type: SpeciesReference
stoichiometry: 1.0
species: 463999

464772
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Acetyl-D-glucosaminyldiphosphodolichol, human liver homolog_C1160H1898N10O120P20

450431
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Butyrate (n-C4:0)_C4H7O2

990072
type: Reaction
product: 497150
product: 497162
name: guanidinoacetate N-methyltransferase (c)
is: http://identifiers.org/ec-code/2.1.1.2
reactant: 497138
product: 497174
is: ENSBTAG00000004112.3
reversible: true
notes: R_GACMTRc subsystem: Urea cycle/amino group metabolism R_GACMTRc equation: [c] : amet + gudac <==> ahcys + creat + h
fast: false
reactant: 497126

497150
type: SpeciesReference
stoichiometry: 1.0
species: 448813

497162
type: SpeciesReference
stoichiometry: 1.0
species: 451792

451792
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Creatine_C4H9N3O2

497138
type: SpeciesReference
stoichiometry: 1.0
species: 449236

497174
type: SpeciesReference
stoichiometry: 1.0
species: 458794

497126
type: SpeciesReference
stoichiometry: 1.0
species: 458576

444769
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: _3',5'-Cyclic GMP_C10H11N5O7P

991344
type: Reaction
reactant: 508626
product: 509098
reactant: 508760
reactant: 508565
reactant: 508614
product: 509159
product: 509172
product: 508989
product: 508928
product: 509061
reactant: 508723
reactant: 508808
product: 509025
product: 508965
product: 508904
reactant: 508711
reversible: false
product: 509074
product: 509110
notes: R_FAOXC2251836x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2251836x equation: [x] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_FAOXC180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC180x equation: [x] : coa + h2o + nad + o2 + stcoa --> accoa + h + h2o2 + nadh + pmtcoa R_FAOXC241181x subsystem: Fatty acid oxidation, peroxisome R_FAOXC241181x equation: [x] : (3) coa + (3) h2o + (3) nad + nrvnccoa + (3) o2 --> (3) accoa + (3) h + (3) h2o2 + (3) nadh + odecoa R_PEROXx subsystem: Fatty acid oxidation, peroxisome R_PEROXx equation: [x] : (3) coa + (3) h2o + (3) nad + (2) o2 + pristcoa --> accoa + dmnoncoa + (3) h + (2) h2o2 + (3) nadh + (2) ppcoa R_FAOXC2452253x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2452253x equation: [x] : coa + h2o + nad + o2 + tetpent3coa --> accoa + clpndcoa + h + h2o2 + nadh R_FAOXC2252053x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2252053x equation: [x] : coa + dcsptn1coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + tmndnccoa R_FAOXC183806x subsystem: Fatty acid oxidation, peroxisome R_FAOXC183806x equation: [x] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC200180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC200180x equation: [x] : arachcoa + coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + stcoa R_ACACT7p subsystem: Fatty Acid Metabolism R_ACACT7p equation: [x] : 3ohdcoa + coa --> accoa + tdcoa R_ACACT8p subsystem: Fatty Acid Metabolism R_ACACT8p equation: [x] : 3ohodcoa + coa --> accoa + pmtcoa R_FAOXC246226x subsystem: Fatty acid oxidation, peroxisome R_FAOXC246226x equation: [x] : coa + h2o + nad + o2 + tethex3coa --> accoa + c226coa + h + h2o2 + nadh R_ACACT5p subsystem: Fatty Acid Metabolism R_ACACT5p equation: [x] : 3oddcoa + coa --> accoa + dcacoa R_FAOXC260240x subsystem: Fatty acid oxidation, peroxisome R_FAOXC260240x equation: [x] : coa + h2o + hexccoa + nad + o2 --> accoa + h + h2o2 +…
reactant: 508675
reactant: 508663
reactant: 508844
reactant: 508868
reactant: 508651
reactant: 508832
reactant: 508748
reactant: 508820
product: 509134
reactant: 508736
reactant: 508880
product: 509147
reactant: 508589
fast: false
reactant: 508577
product: 509037
product: 508916
reactant: 508796
reactant: 508784
reactant: 508602
reactant: 508699
product: 509013
reactant: 508772
product: 509122
product: 509086
reactant: 508856
reactant: 508687
product: 508977
is: http://identifiers.org/ec-code/2.3.1.16
is: ENSBTAG00000008567.4
product: 508892
product: 509001
product: 508953
product: 509049
reactant: 508638
product: 508940
is: http://identifiers.org/ec-code/1.3.99.3

508626
type: SpeciesReference
stoichiometry: 35.0
species: 458770

509098
type: SpeciesReference
stoichiometry: 2.0
species: 470204

508760
type: SpeciesReference
stoichiometry: 1.0
species: 459241

508565
type: SpeciesReference
stoichiometry: 1.0
species: 466856

508614
type: SpeciesReference
stoichiometry: 1.0
species: 462514

509159
type: SpeciesReference
stoichiometry: 39.0
species: 447725

509172
type: SpeciesReference
stoichiometry: 1.0
species: 453072

508989
type: SpeciesReference
stoichiometry: 1.0
species: 469032

508928
type: SpeciesReference
stoichiometry: 1.0
species: 469129

509061
type: SpeciesReference
stoichiometry: 2.0
species: 466988

508723
type: SpeciesReference
stoichiometry: 1.0
species: 445251

445251
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: _3-Oxododecanoyl-CoA_C33H52N7O18P3S

508808
type: SpeciesReference
stoichiometry: 1.0
species: 445239

445239
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: _3-Oxodecanoyl-CoA_C31H48N7O18P3S

509025
type: SpeciesReference
stoichiometry: 1.0
species: 448669

508965
type: SpeciesReference
stoichiometry: 1.0
species: 465645

508904
type: SpeciesReference
stoichiometry: 2.0
species: 466856

508711
type: SpeciesReference
stoichiometry: 1.0
species: 469032

509074
type: SpeciesReference
stoichiometry: 1.0
species: 451350

509110
type: SpeciesReference
stoichiometry: 35.0
species: 458879

508675
type: SpeciesReference
stoichiometry: 2.0
species: 453216

508663
type: SpeciesReference
stoichiometry: 23.0
species: 465294

508844
type: SpeciesReference
stoichiometry: 1.0
species: 469721

508868
type: SpeciesReference
stoichiometry: 1.0
species: 445263

445263
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: _3-Oxohexadecanoyl-CoA_C37H60N7O18P3S

508651
type: SpeciesReference
stoichiometry: 1.0
species: 469129

508832
type: SpeciesReference
stoichiometry: 1.0
species: 469528

508748
type: SpeciesReference
stoichiometry: 1.0
species: 448669

508820
type: SpeciesReference
stoichiometry: 1.0
species: 470204

509134
type: SpeciesReference
stoichiometry: 1.0
species: 462827

508736
type: SpeciesReference
stoichiometry: 1.0
species: 450479

508880
type: SpeciesReference
stoichiometry: 1.0
species: 469649

509147
type: SpeciesReference
stoichiometry: 1.0
species: 453384

508589
type: SpeciesReference
stoichiometry: 1.0
species: 467353

467353
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: pristanoyl coa_C40H68N7O17P3S

508577
type: SpeciesReference
stoichiometry: 1.0
species: 445287

445287
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: _3-Oxohexacosyl-CoA_C47H80N7O18P3S

509037
type: SpeciesReference
stoichiometry: 1.0
species: 449753

508916
type: SpeciesReference
stoichiometry: 1.0
species: 462514

508796
type: SpeciesReference
stoichiometry: 35.0
species: 464578

508784
type: SpeciesReference
stoichiometry: 1.0
species: 445299

508602
type: SpeciesReference
stoichiometry: 1.0
species: 465174

508699
type: SpeciesReference
stoichiometry: 41.0
species: 451671

509013
type: SpeciesReference
stoichiometry: 1.0
species: 450479

508772
type: SpeciesReference
stoichiometry: 1.0
species: 445275

445275
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: _3-Oxooctadecanoyl-CoA_C39H64N7O18P3S

509122
type: SpeciesReference
stoichiometry: 1.0
species: 470507

470507
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: tetracosanoyl-CoA (n-C24:0CoA)_C45H78N7O17P3S

509086
type: SpeciesReference
stoichiometry: 4.0
species: 465475

508856
type: SpeciesReference
stoichiometry: 1.0
species: 462827

508687
type: SpeciesReference
stoichiometry: 1.0
species: 449657

508977
type: SpeciesReference
stoichiometry: 1.0
species: 449657

508892
type: SpeciesReference
stoichiometry: 1.0
species: 454246

509001
type: SpeciesReference
stoichiometry: 1.0
species: 469480

469480
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Tetradecanoyl-CoA (n-C14:0CoA)_C35H58N7O17P3S

508953
type: SpeciesReference
stoichiometry: 35.0
species: 464627

509049
type: SpeciesReference
stoichiometry: 23.0
species: 458673

508638
type: SpeciesReference
stoichiometry: 1.0
species: 469576

508940
type: SpeciesReference
stoichiometry: 1.0
species: 453216

452166
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), free chain_C45H66N2O49S4

987709
type: Reaction
reversible: false
product: 475937
name: threonine synthase
fast: false
is: http://identifiers.org/ec-code/4.2.3.1
is: ENSBTAG00000009117.3
reactant: 475913
reactant: 475925
product: 475949
notes: R_THRS subsystem: Glycine, Serine, and Threonine Metabolism R_THRS equation: [c] : h2o + phom --> pi + thr-L

475937
type: SpeciesReference
stoichiometry: 1.0
species: 470023

475913
type: SpeciesReference
stoichiometry: 1.0
species: 458685

475925
type: SpeciesReference
stoichiometry: 1.0
species: 466639

466639
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: O-Phospho-L-homoserine_C4H8NO6P

475949
type: SpeciesReference
stoichiometry: 1.0
species: 466736

466166
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Palmitoyl-ACP (n-C16:0ACP)_C27H51N2O8PRS

464133
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: myo-Inositol hexakisphosphate_C6H6O24P6

997832
type: Reaction
is: ENSBTAG00000003199.3
product: 572695
reactant: 572671
name: GDPFuc Golgi transport via CMP antiport
notes: R_GDPFUCtg subsystem: Transport, Golgi Apparatus R_GDPFUCtg equation: gdpfuc[c] + gmp[g] <==> gdpfuc[g] + gmp[c]
reactant: 572659
fast: false
reversible: true
product: 572683

572695
type: SpeciesReference
stoichiometry: 1.0
species: 457283

572671
type: SpeciesReference
stoichiometry: 1.0
species: 458094

572659
type: SpeciesReference
stoichiometry: 1.0
species: 457271

572683
type: SpeciesReference
stoichiometry: 1.0
species: 458070

470615
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Tyrosine_C9H11NO3

452251
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 4_C31H49NO29S

464991
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: NMN_C11H14N2O8P

463673
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Melatonin_C13H16N2O2

458106
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: GMP_C10H12N5O8P

987757
type: Reaction
product: 476264
product: 476252
reactant: 476216
reactant: 476228
reversible: false
name: riboflavin kinase
is: http://identifiers.org/ec-code/2.7.1.26
notes: R_RBFK subsystem: Riboflavin Metabolism R_RBFK equation: [c] : atp + ribflv --> adp + fmn + h
product: 476240
is: ENSBTAG00000019345.2
fast: false

476264
type: SpeciesReference
stoichiometry: 1.0
species: 458794

476252
type: SpeciesReference
stoichiometry: 1.0
species: 455787

476216
type: SpeciesReference
stoichiometry: 1.0
species: 468213

476228
type: SpeciesReference
stoichiometry: 1.0
species: 449983

476240
type: SpeciesReference
stoichiometry: 1.0
species: 448462

443815
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: _10-formyltetrahydrofolate-[Glu](7)_C50H57N13O25

449067
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: D-Alanine_C3H7NO2

444105
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _17alpha-Hydroxyprogesterone_C21H30O3

988346
type: Reaction
reversible: true
product: 481582
reactant: 481534
fast: false
name: S-Formylglutathione hydralase
is: http://identifiers.org/ec-code/3.1.2.12
product: 481558
is: ENSBTAG00000003415.4
product: 481570
reactant: 481546
notes: R_SFGTH subsystem: Tyrosine metabolism R_SFGTH equation: [c] : Sfglutth + h2o <==> for + gthrd + h

481582
type: SpeciesReference
stoichiometry: 1.0
species: 458794

481534
type: SpeciesReference
stoichiometry: 1.0
species: 447348

481558
type: SpeciesReference
stoichiometry: 1.0
species: 455859

481570
type: SpeciesReference
stoichiometry: 1.0
species: 458456

481546
type: SpeciesReference
stoichiometry: 1.0
species: 458685

989975
type: Reaction
reactant: 496355
is: ENSBTAG00000001299.4
reactant: 496331
reactant: 496367
reversible: false
reactant: 496343
product: 496427
product: 496415
product: 496391
product: 496403
reactant: 496379
fast: false
notes: R_P4507B11r subsystem: Bile Acid Biosynthesis R_P4507B11r equation: [r] : h + nadph + o2 + xol25oh --> h2o + nadp + xoltri25 R_P4507B12r subsystem: Bile Acid Biosynthesis R_P4507B12r equation: [r] : h + nadph + o2 + xol27oh --> h2o + nadp + xoltri27

496355
type: SpeciesReference
stoichiometry: 2.0
species: 464747

496331
type: SpeciesReference
stoichiometry: 2.0
species: 465282

496367
type: SpeciesReference
stoichiometry: 1.0
species: 471456

471456
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _25-Hydroxycholesterol_C27H46O2

496343
type: SpeciesReference
stoichiometry: 1.0
species: 471480

471480
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _27-Hydroxycholesterol_C27H46O2

496427
type: SpeciesReference
stoichiometry: 1.0
species: 471685

496415
type: SpeciesReference
stoichiometry: 2.0
species: 464687

496391
type: SpeciesReference
stoichiometry: 1.0
species: 471697

471697
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _7-alpha,27-Dihydroxycholesterol_C27H46O3

496403
type: SpeciesReference
stoichiometry: 2.0
species: 458758

496379
type: SpeciesReference
stoichiometry: 2.0
species: 458867

455340
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: estrone glucuronide_C24H30O8

469805
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al_C27H46O4

987457
type: Reaction
reactant: 473670
reversible: false
product: 473694
product: 473730
reactant: 473682
product: 473718
product: 473706
fast: false
notes: R_SLCBK1 subsystem: Sphingolipid Metabolism R_SLCBK1 equation: [c] : atp + sphgn --> adp + h + sph1p R_SPHK21c subsystem: Sphingolipid Metabolism R_SPHK21c equation: [c] : atp + sphings --> adp + h + sphs1p
is: ENSBTAG00000009872.4
reactant: 473658

473670
type: SpeciesReference
stoichiometry: 1.0
species: 468851

468851
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Sphingosine_C18H38NO2

473694
type: SpeciesReference
stoichiometry: 1.0
species: 468803

473730
type: SpeciesReference
stoichiometry: 2.0
species: 458794

473682
type: SpeciesReference
stoichiometry: 1.0
species: 468827

473718
type: SpeciesReference
stoichiometry: 2.0
species: 448462

473706
type: SpeciesReference
stoichiometry: 1.0
species: 468923

468923
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Sphingosine 1-phosphate_C18H37NO5P

473658
type: SpeciesReference
stoichiometry: 2.0
species: 449983

446478
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: haxglutamyl folate (DHF)_C44H49N12O21

994203
type: Reaction
reactant: 536374
product: 536398
name: hydroxymethylbilane synthase
fast: false
reactant: 536386
product: 536410
is: http://identifiers.org/ec-code/4.3.1.8
is: ENSBTAG00000005364.3
notes: R_HMBS subsystem: Heme Biosynthesis R_HMBS equation: [c] : h2o + (4) ppbng --> hmbil + (4) nh4
reversible: false

536374
type: SpeciesReference
stoichiometry: 4.0
species: 466952

536398
type: SpeciesReference
stoichiometry: 4.0
species: 464834

536386
type: SpeciesReference
stoichiometry: 1.0
species: 458685

536410
type: SpeciesReference
stoichiometry: 1.0
species: 459337

453832
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Dehydroepiandrosterone sulfate_C19H27O5S

461032
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 38_C54H91N3O41

461956
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate II (core 4-linked)_C89H142N7O72S3X

990108
type: Reaction
notes: R_CHOLt4 subsystem: Transport, Extracellular R_CHOLt4 equation: chol[e] + na1[e] <==> chol[c] + na1[c]
reactant: 497318
product: 497355
product: 497342
reversible: true
is: ENSBTAG00000004352.3
fast: false
name: choline, sodium cotransport
reactant: 497330

497318
type: SpeciesReference
stoichiometry: 1.0
species: 464470

497355
type: SpeciesReference
stoichiometry: 1.0
species: 464458

497342
type: SpeciesReference
stoichiometry: 1.0
species: 450878

497330
type: SpeciesReference
stoichiometry: 1.0
species: 450890

996421
type: Reaction
reactant: 558460
fast: false
reactant: 558448
name: glycine reversible transport via sodium and chloride symport (3:1:1)
is: ENSBTAG00000006043.4
is: ENSBTAG00000000185.4
reactant: 558472
is: ENSBTAG00000039095.1
product: 558496
product: 558508
is: ENSBTAG00000014300.3
reversible: true
notes: R_GLYt7_LPAREN_311_RPAREN_r subsystem: Transport, Extracellular R_GLYt7_LPAREN_311_RPAREN_r equation: cl[e] + gly[e] + (3) na1[e] <==> cl[c] + gly[c] + (3) na1[c]
product: 558484

558460
type: SpeciesReference
stoichiometry: 1.0
species: 457719

558448
type: SpeciesReference
stoichiometry: 3.0
species: 464470

558472
type: SpeciesReference
stoichiometry: 1.0
species: 451289

558496
type: SpeciesReference
stoichiometry: 1.0
species: 451277

558508
type: SpeciesReference
stoichiometry: 3.0
species: 464458

558484
type: SpeciesReference
stoichiometry: 1.0
species: 457707

449477
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: P1,P4-Bis(5'-adenosyl) tetraphosphate_C20H24N10O19P4

995304
type: Reaction
notes: R_MI4PP subsystem: Inositol Phosphate Metabolism R_MI4PP equation: [c] : h2o + mi4p-D --> inost + pi R_MI3PP subsystem: Inositol Phosphate Metabolism R_MI3PP equation: [c] : h2o + mi3p-D --> inost + pi R_MI1PP subsystem: Inositol Phosphate Metabolism R_MI1PP equation: [c] : h2o + mi1p-D --> inost + pi
product: 548283
reactant: 548259
product: 548271
fast: false
reactant: 548234
reactant: 548246
reactant: 548222
is: ENSBTAG00000004270.4
is: http://identifiers.org/ec-code/3.1.3.25
reversible: false

548283
type: SpeciesReference
stoichiometry: 3.0
species: 460425

548259
type: SpeciesReference
stoichiometry: 3.0
species: 458685

548271
type: SpeciesReference
stoichiometry: 3.0
species: 466736

548234
type: SpeciesReference
stoichiometry: 1.0
species: 464095

464095
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _1D-myo-Inositol 3-phosphate_C6H11O9P

548246
type: SpeciesReference
stoichiometry: 1.0
species: 464107

548222
type: SpeciesReference
stoichiometry: 1.0
species: 464059

994884
type: Reaction
product: 544778
is: ENSBTAG00000002979.4
reactant: 544681
is: ENSBTAG00000013498.2
product: 544802
reactant: 544717
is: ENSBTAG00000020848.4
is: ENSBTAG00000009232.4
is: ENSBTAG00000005978.4
fast: false
product: 544742
notes: R_PI45P3K subsystem: Inositol Phosphate Metabolism R_PI45P3K equation: [c] : atp + pail45p_hs --> adp + h + pail345p_hs R_PIK3 subsystem: Inositol Phosphate Metabolism R_PIK3 equation: [c] : atp + pail_hs --> adp + h + pail3p_hs R_PI5P3K subsystem: Inositol Phosphate Metabolism R_PI5P3K equation: [c] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI4P3K subsystem: Inositol Phosphate Metabolism R_PI4P3K equation: [c] : atp + pail4p_hs --> adp + h + pail34p_hs
reactant: 544730
product: 544754
reversible: false
is: ENSBTAG00000010989.4
is: http://identifiers.org/ec-code/2.7.1.137
product: 544790
reactant: 544705
is: http://identifiers.org/ec-code/2.7.1.153
product: 544766
reactant: 544693
is: ENSBTAG00000006909.4
is: ENSBTAG00000002350.4

544778
type: SpeciesReference
stoichiometry: 4.0
species: 448462

544681
type: SpeciesReference
stoichiometry: 1.0
species: 466106

544802
type: SpeciesReference
stoichiometry: 4.0
species: 458794

544717
type: SpeciesReference
stoichiometry: 1.0
species: 466130

544742
type: SpeciesReference
stoichiometry: 1.0
species: 465949

544730
type: SpeciesReference
stoichiometry: 1.0
species: 466070

544754
type: SpeciesReference
stoichiometry: 1.0
species: 465998

544790
type: SpeciesReference
stoichiometry: 1.0
species: 466022

544705
type: SpeciesReference
stoichiometry: 1.0
species: 466046

544766
type: SpeciesReference
stoichiometry: 1.0
species: 465973

544693
type: SpeciesReference
stoichiometry: 4.0
species: 449983

988946
type: Reaction
notes: R_MG1er subsystem: N-Glycan Biosynthesis R_MG1er equation: [r] : g3m8masn + h2o --> g2m8masn + glc-D
is: ENSBTAG00000001844.4
product: 487635
reversible: false
reactant: 487599
is: http://identifiers.org/ec-code/3.2.1.106
name: mannosyl-oligosaccharide glucosidase, endoplasmic reticulum
product: 487623
reactant: 487611
fast: false

487635
type: SpeciesReference
stoichiometry: 1.0
species: 457404

487599
type: SpeciesReference
stoichiometry: 1.0
species: 456501

456501
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: (alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C88H147N2O70X

487623
type: SpeciesReference
stoichiometry: 1.0
species: 456463

487611
type: SpeciesReference
stoichiometry: 1.0
species: 458758

471576
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _7alpha-Hydroxycholest-4-en-3-one_C27H44O2

446322
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-Methylthio-5-deoxy-D-ribose 1-phosphate_C6H11O7PS

457973
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: glycogen, structure 4 (glycogenin-1,6-{2[1,4-Glc], [1,4-Glc]})_C18H31O16X

455028
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: ecgonine_C9H14NO3

469697
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: tetracosatetraenoyl coenzyme A_C45H70N7O17P3S

444370
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _2-Carboxy-2,3-dihydro-5,6-dihydroxyindole_C9H8NO4

467449
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Proline_C5H9NO2

455304
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _16-Glucuronide-estriol_C24H32O9

987529
type: Reaction
fast: false
notes: R_HSD17B7r subsystem: Steroid Metabolism R_HSD17B7r equation: [r] : estrone + h + nadph --> estradiol + nadp R_HSD17B9r subsystem: Steroid Metabolism R_HSD17B9r equation: [r] : andrstrn + h + nadph + (1.5) o2 --> eandrstrn + (2) h2o + nadp
is: http://identifiers.org/ec-code/1.1.1.62
product: 474164
product: 474127
reactant: 474091
reversible: false
reactant: 474079
reactant: 474115
product: 474151
is: ENSBTAG00000005976.4
reactant: 474067
reactant: 474103
product: 474139

474164
type: SpeciesReference
stoichiometry: 1.0
species: 454992

474127
type: SpeciesReference
stoichiometry: 2.0
species: 464687

474091
type: SpeciesReference
stoichiometry: 2.0
species: 458867

474079
type: SpeciesReference
stoichiometry: 2.0
species: 464747

474115
type: SpeciesReference
stoichiometry: 1.0
species: 455328

474151
type: SpeciesReference
stoichiometry: 2.0
species: 458758

474067
type: SpeciesReference
stoichiometry: 1.5
species: 465282

474103
type: SpeciesReference
stoichiometry: 1.0
species: 449405

449405
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Androsterone_C19H30O2

474139
type: SpeciesReference
stoichiometry: 1.0
species: 455220

455220
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Estradiol_C18H24O2

446877
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Cystine_C6H12N2O4S2

454074
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dITP_C10H11N4O13P3

988922
type: Reaction
reactant: 487068
product: 487154
reactant: 487104
reactant: 487117
product: 487142
reactant: 487092
product: 487166
notes: R_S6T3g subsystem: Keratan sulfate biosynthesis R_S6T3g equation: [g] : ksii_core2_pre10 + paps --> h + ksii_core2 + pap R_S6T24g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T24g equation: [g] : cs_e_pre4 + paps --> cs_e_pre5b + h + pap R_S6T20g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T20g equation: [g] : cs_c_pre3 + paps --> cspg_c + h + pap R_S6T19g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T19g equation: [g] : cs_pre + (2) paps --> cs_c,d,e_pre1 + (2) h + (2) pap R_S6T18g subsystem: Keratan sulfate biosynthesis R_S6T18g equation: [g] : ksii_core4_pre10 + paps --> h + ksii_core4 + pap R_S6T15g subsystem: Keratan sulfate biosynthesis R_S6T15g equation: [g] : ksi_pre36 + paps --> h + ksi + pap R_S6T21g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T21g equation: [g] : cs_d_pre4 + paps --> cs_d_pre5 + h + pap
reactant: 487044
product: 487214
product: 487190
product: 487238
product: 487226
reactant: 487129
reversible: false
is: ENSBTAG00000011014.2
fast: false
product: 487202
is: http://identifiers.org/ec-code/2.8.2.17
reactant: 487080
reactant: 487056
product: 487178

487068
type: SpeciesReference
stoichiometry: 1.0
species: 452299

487154
type: SpeciesReference
stoichiometry: 1.0
species: 452202

487104
type: SpeciesReference
stoichiometry: 1.0
species: 452563

487117
type: SpeciesReference
stoichiometry: 1.0
species: 461540

487142
type: SpeciesReference
stoichiometry: 1.0
species: 461177

487092
type: SpeciesReference
stoichiometry: 1.0
species: 452599

487166
type: SpeciesReference
stoichiometry: 1.0
species: 452660

452660
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate C (GalNAc6S-GlcA) proteoglycan_C45H66N2O45S3X

487044
type: SpeciesReference
stoichiometry: 1.0
species: 461968

487214
type: SpeciesReference
stoichiometry: 1.0
species: 461751

487190
type: SpeciesReference
stoichiometry: 1.0
species: 452431

452431
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 5_C45H65N2O48S4X

487238
type: SpeciesReference
stoichiometry: 1.0
species: 452587

452587
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5b_C45H64N2O51S5X

487226
type: SpeciesReference
stoichiometry: 1.0
species: 461945

487129
type: SpeciesReference
stoichiometry: 1.0
species: 461775

487202
type: SpeciesReference
stoichiometry: 8.0
species: 466202

487080
type: SpeciesReference
stoichiometry: 8.0
species: 466226

487056
type: SpeciesReference
stoichiometry: 1.0
species: 452419

487178
type: SpeciesReference
stoichiometry: 8.0
species: 458819

990132
type: Reaction
product: 497535
reactant: 497451
product: 497499
product: 497560
product: 497511
product: 497572
reactant: 497391
reactant: 497415
product: 497487
reactant: 497475
reactant: 497463
reversible: false
fast: false
reactant: 497439
reactant: 497427
is: http://identifiers.org/ec-code/3.5.1.12
is: ENSBTAG00000019129.4
product: 497547
notes: R_BTND1 subsystem: Biotin Metabolism R_BTND1 equation: [c] : biocyt + h2o --> btn + lys-L R_BTND1n subsystem: Biotin Metabolism R_BTND1n equation: [n] : biocyt + h2o --> btn + lys-L R_BTNDe subsystem: Biotin Metabolism R_BTNDe equation: [e] : biocyt + h2o --> btn + lys-L R_BTNDm subsystem: Biotin Metabolism R_BTNDm equation: [m] : biocyt + h2o --> btn + lys-L
reactant: 497403
product: 497523

497535
type: SpeciesReference
stoichiometry: 1.0
species: 462959

497451
type: SpeciesReference
stoichiometry: 1.0
species: 458746

497499
type: SpeciesReference
stoichiometry: 1.0
species: 450371

497560
type: SpeciesReference
stoichiometry: 1.0
species: 450395

497511
type: SpeciesReference
stoichiometry: 1.0
species: 450383

497572
type: SpeciesReference
stoichiometry: 1.0
species: 462971

462971
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: L-Lysine_C6H15N2O2

497391
type: SpeciesReference
stoichiometry: 1.0
species: 458733

497415
type: SpeciesReference
stoichiometry: 1.0
species: 458697

497487
type: SpeciesReference
stoichiometry: 1.0
species: 462935

497475
type: SpeciesReference
stoichiometry: 1.0
species: 450287

497463
type: SpeciesReference
stoichiometry: 1.0
species: 450299

497439
type: SpeciesReference
stoichiometry: 1.0
species: 458685

497427
type: SpeciesReference
stoichiometry: 1.0
species: 450274

450274
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Biocytin_C16H28N4O4S

497547
type: SpeciesReference
stoichiometry: 1.0
species: 462947

497403
type: SpeciesReference
stoichiometry: 1.0
species: 450311

450311
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Biocytin_C16H28N4O4S

497523
type: SpeciesReference
stoichiometry: 1.0
species: 450359

993975
type: Reaction
is: ENSBTAG00000012475.4
reactant: 533793
is: http://identifiers.org/ec-code/1.13.11.31
product: 533805
fast: false
reversible: false
name: Arachidonate 12-lipoxygenase R
notes: R_ALOX12R subsystem: Eicosanoid Metabolism R_ALOX12R equation: [c] : arachd + o2 --> 12RHPET
reactant: 533781

533793
type: SpeciesReference
stoichiometry: 1.0
species: 465234

533805
type: SpeciesReference
stoichiometry: 1.0
species: 443960

443960
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _12R-Hydroperoxyeicosatetraenoate_C20H31O4

533781
type: SpeciesReference
stoichiometry: 1.0
species: 449693

465307
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Superoxide anion_O2

453904
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _7,8-Dihydrofolate_C19H19N7O6

448438
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Adenosine_C10H13N5O4

461431
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 28_C213H341N15O176S8X

469540
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: tetracosapentaenoic acid, n-3_C24H37O2

994401
type: Reaction
fast: false
is: ENSBTAG00000007003.3
reactant: 538970
product: 538994
reversible: false
is: http://identifiers.org/ec-code/2.1.1.45
notes: R_TMDS subsystem: Nucleotides R_TMDS equation: [c] : dump + mlthf --> dhf + dtmp
reactant: 538958
name: thymidylate synthase
product: 538982

538970
type: SpeciesReference
stoichiometry: 1.0
species: 454824

538994
type: SpeciesReference
stoichiometry: 1.0
species: 454691

538958
type: SpeciesReference
stoichiometry: 1.0
species: 464145

538982
type: SpeciesReference
stoichiometry: 1.0
species: 453868

453868
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _7,8-Dihydrofolate_C19H19N7O6

444563
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _2-Oxobutanoate_C4H5O3

988274
type: Reaction
product: 481053
reactant: 481028
product: 481077
reactant: 481016
fast: false
is: http://identifiers.org/ec-code/3.2.1.10
notes: R_O16G1e subsystem: Starch and Sucrose Metabolism R_O16G1e equation: [e] : glygn4 + h2o --> glc-D + glygn5 R_SUCRe subsystem: Galactose metabolism R_SUCRe equation: [e] : h2o + sucr --> fru + glc-D R_O16G2e subsystem: Starch and Sucrose Metabolism R_O16G2e equation: [e] : h2o + strch2 --> glc-D + malt
is: http://identifiers.org/ec-code/3.2.1.26
product: 481065
reversible: false
is: ENSBTAG00000006975.4
product: 481089
reactant: 481041
reactant: 481004

481053
type: SpeciesReference
stoichiometry: 1.0
species: 457985

481028
type: SpeciesReference
stoichiometry: 1.0
species: 457973

481077
type: SpeciesReference
stoichiometry: 1.0
species: 463515

463515
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Maltose_C12H22O11

481016
type: SpeciesReference
stoichiometry: 1.0
species: 469238

469238
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Sucrose_C12H22O11

481065
type: SpeciesReference
stoichiometry: 1.0
species: 456016

456016
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: D-Fructose_C6H12O6

481089
type: SpeciesReference
stoichiometry: 3.0
species: 457368

481041
type: SpeciesReference
stoichiometry: 3.0
species: 458697

481004
type: SpeciesReference
stoichiometry: 1.0
species: 469080

469080
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: starch, structure 2 (1,6-{2[1,4-Glc], [1,4-Glc]})_C18H32O16

996265
type: Reaction
reversible: false
name: Acetylcholinesterase
is: ENSBTAG00000001139.4
notes: R_ACHEe subsystem: Glycerophospholipid Metabolism R_ACHEe equation: [e] : ach + h2o --> ac + chol + h
product: 557407
product: 557419
is: http://identifiers.org/ec-code/3.1.1.7
fast: false
product: 557431
reactant: 557382
reactant: 557394

557407
type: SpeciesReference
stoichiometry: 1.0
species: 458806

557419
type: SpeciesReference
stoichiometry: 1.0
species: 447533

447533
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Acetate_C2H3O2

557431
type: SpeciesReference
stoichiometry: 1.0
species: 450890

557382
type: SpeciesReference
stoichiometry: 1.0
species: 458697

557394
type: SpeciesReference
stoichiometry: 1.0
species: 448088

448088
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Acetylcholine_C7H16NO2

454703
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: dTMP_C10H13N2O8P

448849
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

455799
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: N4-{N-Acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,3)-[N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,6)]-beta-D-mannosyl-(1,4)-N-acetyl-beta-D-glucosaminyl-(1,4)-[alpha-L-fucosyl-(1,6)]-N-acetyl-beta-D-glucosaminyl}asparagine_C56H93N4O39X

471625
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: cholesterol ester (from FULLR2)_C27H45FULLR2CO2

463563
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Maltotriose_C18H32O16

447713
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Acetyl-CoA_C23H34N7O17P3S

457259
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610

997159
type: Reaction
is: http://identifiers.org/ec-code/3.2.1.21
is: ENSBTAG00000020363.4
notes: R_BDG2HCGHD subsystem: Stilbene, coumarine and lignin biosynthesis R_BDG2HCGHD equation: [c] : bdg2hc + h2o --> 2coum + glc-D + h
product: 564864
reactant: 564838
fast: false
reactant: 564825
reversible: false
name: beta-D-Glucosyl-2-coumarinate glucohydrolase
product: 564877
product: 564851

564864
type: SpeciesReference
stoichiometry: 1.0
species: 457356

564838
type: SpeciesReference
stoichiometry: 1.0
species: 450104

564825
type: SpeciesReference
stoichiometry: 1.0
species: 458685

564877
type: SpeciesReference
stoichiometry: 1.0
species: 458794

564851
type: SpeciesReference
stoichiometry: 1.0
species: 444382

990816
type: Reaction
is: ENSBTAG00000014432.4
product: 503183
name: S-Adenosyl-L-methionine:histamine N-tele-methyltransferase
notes: R_SAMHISTA subsystem: Histidine Metabolism R_SAMHISTA equation: [c] : amet + hista --> ahcys + h + mhista
is: http://identifiers.org/ec-code/2.1.1.8
product: 503207
reversible: false
product: 503195
reactant: 503158
reactant: 503171
fast: false

503183
type: SpeciesReference
stoichiometry: 1.0
species: 448813

503207
type: SpeciesReference
stoichiometry: 1.0
species: 458794

503195
type: SpeciesReference
stoichiometry: 1.0
species: 463915

503158
type: SpeciesReference
stoichiometry: 1.0
species: 449236

503171
type: SpeciesReference
stoichiometry: 1.0
species: 459313

994179
type: Reaction
reactant: 535853
reversible: false
product: 535901
is: ENSBTAG00000007121.4
is: http://identifiers.org/ec-code/2.7.1.21
product: 535889
product: 535877
reactant: 535829
notes: R_TMDK1 subsystem: Nucleotides R_TMDK1 equation: [c] : atp + thymd --> adp + dtmp + h R_DURIK1 subsystem: Nucleotides R_DURIK1 equation: [c] : atp + duri --> adp + dump + h
product: 535865
reactant: 535841
fast: false

535853
type: SpeciesReference
stoichiometry: 1.0
species: 470071

535901
type: SpeciesReference
stoichiometry: 2.0
species: 458794

535889
type: SpeciesReference
stoichiometry: 1.0
species: 454691

535877
type: SpeciesReference
stoichiometry: 2.0
species: 448462

535829
type: SpeciesReference
stoichiometry: 1.0
species: 454860

535865
type: SpeciesReference
stoichiometry: 1.0
species: 454824

535841
type: SpeciesReference
stoichiometry: 2.0
species: 449983

990432
type: Reaction
reversible: false
fast: false
reactant: 500325
notes: R_SBPP1er subsystem: Sphingolipid Metabolism R_SBPP1er equation: [r] : h2o + sph1p --> pi + sphgn R_SBPP3er subsystem: Sphingolipid Metabolism R_SBPP3er equation: [r] : h2o + sphs1p --> pi + sphings
product: 500386
reactant: 500350
reactant: 500337
is: ENSBTAG00000004430.3
product: 500362
product: 500374

500325
type: SpeciesReference
stoichiometry: 1.0
species: 468935

500386
type: SpeciesReference
stoichiometry: 1.0
species: 468839

468839
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Sphinganine_C18H40NO2

500350
type: SpeciesReference
stoichiometry: 2.0
species: 458758

500337
type: SpeciesReference
stoichiometry: 1.0
species: 468815

468815
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Sphinganine 1-phosphate_C18H39NO5P

500362
type: SpeciesReference
stoichiometry: 2.0
species: 466808

500374
type: SpeciesReference
stoichiometry: 1.0
species: 468875

468875
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Sphingosine_C18H38NO2

465706
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: omeprazole_C17H19N3O3S

459541
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: heparan sulfate, degradation product 11_C55H81N3O67S7

453650
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Dihydroxyacetone phosphate_C3H5O6P

994511
type: Reaction
modifier: 540411
is: http://identifiers.org/ec-code/2.1.2.2
reactant: 540327
reversible: false
modifier: 540399
modifier: 540447
is: ENSBTAG00000009188.4
product: 540339
modifier: 540423
is: http://identifiers.org/ec-code/6.3.3.1
modifier: 540471
product: 540363
product: 540375
is: http://identifiers.org/ec-code/6.3.4.13
fast: false
modifier: 540495
modifier: 540459
reactant: 540315
notes: R_GARFT subsystem: IMP Biosynthesis R_GARFT equation: [c] : 10fthf + gar <==> fgam + h + thf R_PRAGSr subsystem: IMP Biosynthesis R_PRAGSr equation: [c] : atp + gly + pram <==> adp + gar + h + pi R_PRAIS subsystem: IMP Biosynthesis R_PRAIS equation: [c] : atp + fpram --> adp + air + (2) h + pi
modifier: 540387
modifier: 540435
product: 540351
modifier: 540483

540327
type: SpeciesReference
stoichiometry: 1.0
species: 455944

540339
type: SpeciesReference
stoichiometry: 1.0
species: 466736

540363
type: SpeciesReference
stoichiometry: 1.0
species: 448897

448897
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-amino-1-(5-phospho-D-ribosyl)imidazole_C8H12N3O7P

540375
type: SpeciesReference
stoichiometry: 2.0
species: 458794

540315
type: SpeciesReference
stoichiometry: 1.0
species: 449983

467183
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-Phospho-beta-D-ribosylamine_C5H11NO7P

540351
type: SpeciesReference
stoichiometry: 1.0
species: 448462

992089
type: Reaction
product: 517187
product: 517224
reversible: false
reactant: 517079
product: 517175
reactant: 517115
reactant: 517091
reactant: 517055
reactant: 517067
reactant: 517103
is: ENSBTAG00000017421.3
product: 517139
product: 517199
product: 517212
is: http://identifiers.org/ec-code/3.2.1.1
notes: R_AMY1e subsystem: Starch and Sucrose Metabolism R_AMY1e equation: [e] : (8) h2o + strch1 --> (8) glc-D + strch2 R_CYSTSERex subsystem: Transport, Extracellular R_CYSTSERex equation: Lcystin[e] + ser-L[c] --> Lcystin[c] + ser-L[e] R_AMY2e subsystem: Starch and Sucrose Metabolism R_AMY2e equation: [e] : glygn2 + (8) h2o --> (8) glc-D + glygn4 R_SERLYSNaex subsystem: Transport, Extracellular R_SERLYSNaex equation: lys-L[c] + na1[e] + ser-L[e] --> lys-L[e] + na1[c] + ser-L[c]
product: 517163
reactant: 517127
reactant: 517043
fast: false
product: 517151

517187
type: SpeciesReference
stoichiometry: 1.0
species: 462947

517224
type: SpeciesReference
stoichiometry: 1.0
species: 457973

517079
type: SpeciesReference
stoichiometry: 1.0
species: 464470

517175
type: SpeciesReference
stoichiometry: 16.0
species: 457368

517115
type: SpeciesReference
stoichiometry: 1.0
species: 468635

517091
type: SpeciesReference
stoichiometry: 16.0
species: 458697

517055
type: SpeciesReference
stoichiometry: 1.0
species: 462935

517067
type: SpeciesReference
stoichiometry: 1.0
species: 468623

517103
type: SpeciesReference
stoichiometry: 1.0
species: 469068

469068
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: starch, structure 1 (1,6-{7[1,4-Glc], 4[1,4-Glc]})_C66H112O56

517139
type: SpeciesReference
stoichiometry: 1.0
species: 468623

517199
type: SpeciesReference
stoichiometry: 1.0
species: 469080

517212
type: SpeciesReference
stoichiometry: 1.0
species: 468635

517163
type: SpeciesReference
stoichiometry: 1.0
species: 464458

517127
type: SpeciesReference
stoichiometry: 1.0
species: 457948

457948
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]})_C66H111O56X

517043
type: SpeciesReference
stoichiometry: 1.0
species: 446889

517151
type: SpeciesReference
stoichiometry: 1.0
species: 446877

991440
type: Reaction
is: ENSBTAG00000016867.4
product: 509776
name: testicular 17-beta-hydroxysteroid dehydrogenase
reactant: 509740
notes: R_HSD17B3r subsystem: Steroid Metabolism R_HSD17B3r equation: [r] : andrstndn + h + nadph --> nadp + tststerone
fast: false
is: http://identifiers.org/ec-code/1.1.1.62
product: 509788
reactant: 509764
reversible: false
reactant: 509752

509776
type: SpeciesReference
stoichiometry: 1.0
species: 470409

509740
type: SpeciesReference
stoichiometry: 1.0
species: 464747

509788
type: SpeciesReference
stoichiometry: 1.0
species: 464687

509764
type: SpeciesReference
stoichiometry: 1.0
species: 458867

509752
type: SpeciesReference
stoichiometry: 1.0
species: 449393

468334
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: de-Fuc, reducing GlcNAc removed form of PA6 (w/o peptide linkage)_C76H123N5O57

462429
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Leukotriene C4_C30H45N3O9S

990792
type: Reaction
product: 503037
is: ENSBTAG00000001154.4
fast: false
reactant: 503001
name: diacylglycerol acyltransferase
reactant: 503013
product: 503025
is: ENSBTAG00000026356.3
notes: R_DGAT subsystem: Triacylglycerol Synthesis R_DGAT equation: [c] : Rtotal3coa + dag_hs --> coa + tag_hs
is: ENSBTAG00000015091.3
reversible: false

503037
type: SpeciesReference
stoichiometry: 1.0
species: 469298

503001
type: SpeciesReference
stoichiometry: 1.0
species: 447153

447153
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: R total 3 Coenzyme A_CO2FULLR3C21H31N7O15P3S

503013
type: SpeciesReference
stoichiometry: 1.0
species: 452951

503025
type: SpeciesReference
stoichiometry: 1.0
species: 451593

995592
type: Reaction
is: http://identifiers.org/ec-code/2.4.1.134
product: 550284
product: 550272
reactant: 550248
name: UDP-D-galactose:galactosylxylose galactosyltransferase, Golgi apparatus
reactant: 550260
reversible: false
product: 550296
is: ENSBTAG00000037523.1
fast: false
notes: R_GALT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALT2g equation: [g] : lxser + udpgal --> h + l2xser + udp

550284
type: SpeciesReference
stoichiometry: 1.0
species: 458819

550272
type: SpeciesReference
stoichiometry: 1.0
species: 470688

550248
type: SpeciesReference
stoichiometry: 1.0
species: 462923

550260
type: SpeciesReference
stoichiometry: 1.0
species: 470848

550296
type: SpeciesReference
stoichiometry: 1.0
species: 462126

462126
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)2-Xyl-L-Ser (protein)_C17H29O14X

445902
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _4-Trimethylammoniobutanal_C7H16NO

995100
type: Reaction
is: http://identifiers.org/ec-code/4.2.1.17
modifier: 546288
modifier: 546434
modifier: 546397
product: 546264
fast: false
modifier: 546384
modifier: 546360
modifier: 546422
modifier: 546336
notes: R_C2M26DCOAHLm subsystem: Limonene and pinene degradation R_C2M26DCOAHLm equation: [m] : c2m26dcoa + h2o <==> 3h26dm5coa R_HACD1m subsystem: Tryptophan metabolism R_HACD1m equation: [m] : aacoa + h + nadh <==> 3hbcoa + nad R_T2M26DCOAHLm subsystem: Limonene and pinene degradation R_T2M26DCOAHLm equation: [m] : h2o + t2m26dcoa <==> 3h26dm5coa R_ECOAH12m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ECOAH12m equation: [m] : 2mp2coa + h2o <==> 3hibutcoa R_PRPNCOAHYDm subsystem: beta-Alanine metabolism R_PRPNCOAHYDm equation: [m] : h2o + prpncoa --> 3hpcoa R_ECOAH9m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ECOAH9m equation: [m] : 2mb2coa + h2o <==> 3hmbcoa R_ECOAH1m subsystem: Tryptophan metabolism R_ECOAH1m equation: [m] : 3hbcoa <==> b2coa + h2o R_ACACT1rm subsystem: Tryptophan metabolism R_ACACT1rm equation: [m] : (2) accoa <==> aacoa + coa
modifier: 546276
modifier: 546312
is: ENSBTAG00000006517.3
is: ENSBTAG00000010083.3
modifier: 546446
modifier: 546458
modifier: 546410
reactant: 546240
reactant: 546252
modifier: 546372
modifier: 546348
modifier: 546324
modifier: 546300
reversible: false
is: http://identifiers.org/ec-code/1.1.1.35
is: http://identifiers.org/ec-code/2.3.1.9

444938
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670

546264
type: SpeciesReference
stoichiometry: 1.0
species: 445011

444962
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670

444974
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670

444889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670

450515
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670

546240
type: SpeciesReference
stoichiometry: 1.0
species: 458733

546252
type: SpeciesReference
stoichiometry: 1.0
species: 467644

444551
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670

469262
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670

994191
type: Reaction
reversible: false
is: http://identifiers.org/ec-code/1.2.1.39
reactant: 536034
is: ENSBTAG00000020385.3
reactant: 536046
is: http://identifiers.org/ec-code/1.2.1.3
product: 536118
modifier: 536301
product: 536106
modifier: 536313
reactant: 535985
modifier: 536277
reactant: 535997
modifier: 536227
reactant: 536009
modifier: 536289
product: 536082
reactant: 536058
product: 536179
modifier: 536239
modifier: 536350
product: 536155
product: 536203
modifier: 536362
product: 536142
product: 536070
is: http://identifiers.org/ec-code/1.2.1.5
is: http://identifiers.org/ec-code/1.2.1.21
is: ENSBTAG00000036266.1
modifier: 536326
product: 536191
modifier: 536338
reactant: 535937
reactant: 535913
reactant: 535949
is: ENSBTAG00000023068.3
product: 536167
product: 536215
reactant: 535925
reactant: 535961
reactant: 535973
product: 536130
modifier: 536252
fast: false
is: ENSBTAG00000010119.4
reactant: 536021
modifier: 536264
is: ENSBTAG00000009125.4
product: 536094
is: ENSBTAG00000014470.4
notes: R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD19x_LPAREN_P_RPAREN_ subsystem: Phenylalanine metabolism R_ALDD19x_LPAREN_P_RPAREN_ equation: [c] : h2o + nadp + pacald --> (2) h + nadph + pac R_3MOX4HOXPGALDOX subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX equation: [c] : 3m4hpga + h2o + nad --> 3mox4hoxm + (2) h + nadh R_MACOXO subsystem: Histidine Metabolism R_MACOXO equation: [c] : 3mldz + h2o + nad --> 3mlda + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_4HOXPACDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_4HOXPACDOX_LPAREN_NADP_RPAREN_ equation: [c] : 4hoxpacd + h2o + nadp <==> 4hphac + (2) h + nadph R_3M4HDXPAC subsystem: Tyrosine metabolism R_3M4HDXPAC equation: [c] : 3mox4hpac + h2o + nad <==> (2) h + homoval + nadh R_34DHPLACOX subsystem: Tyrosine metabolism R_34DHPLACOX equation: [c] : 34dhpac + h2o + nad --> 34dhpha + (2) h + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ equation: [c] : 3m4hpga + h2o + nadp <==> 3mox4hoxm + (2) h + nadph R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_ALDD19x subsystem: Phenylalanine metabolism R_ALDD19x equation: [c] : h2o + nad + pacald --> (2) h + nadh + pac R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh R_34DHXMANDACOX subsystem: Tyrosine metabolism R_34DHXMANDACOX equation: [c] : 34dhmald + h2o + nad --> 34dhoxmand + (2) h + nadh

536034
type: SpeciesReference
stoichiometry: 1.0
species: 457332

536046
type: SpeciesReference
stoichiometry: 1.0
species: 462210

536118
type: SpeciesReference
stoichiometry: 1.0
species: 444683

445685
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _4-Hydroxyphenylacetate_C8H7O3

536106
type: SpeciesReference
stoichiometry: 1.0
species: 444647

535985
type: SpeciesReference
stoichiometry: 1.0
species: 445095

535997
type: SpeciesReference
stoichiometry: 1.0
species: 464639

536009
type: SpeciesReference
stoichiometry: 2.0
species: 465913

536082
type: SpeciesReference
stoichiometry: 1.0
species: 447521

536058
type: SpeciesReference
stoichiometry: 1.0
species: 444635

536179
type: SpeciesReference
stoichiometry: 23.0
species: 458794

536155
type: SpeciesReference
stoichiometry: 1.0
species: 462174

536203
type: SpeciesReference
stoichiometry: 1.0
species: 464711

536142
type: SpeciesReference
stoichiometry: 2.0
species: 465901

465901
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Phenylacetic acid_C8H7O2

536070
type: SpeciesReference
stoichiometry: 1.0
species: 457888

536191
type: SpeciesReference
stoichiometry: 1.0
species: 445203

445203
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Methoxy-4-hydroxymandelate_C9H9O5

535937
type: SpeciesReference
stoichiometry: 10.0
species: 464518

535913
type: SpeciesReference
stoichiometry: 1.0
species: 445143

535949
type: SpeciesReference
stoichiometry: 1.0
species: 457031

536167
type: SpeciesReference
stoichiometry: 1.0
species: 462138

536215
type: SpeciesReference
stoichiometry: 10.0
species: 464590

535925
type: SpeciesReference
stoichiometry: 1.0
species: 462234

535961
type: SpeciesReference
stoichiometry: 1.0
species: 447617

535973
type: SpeciesReference
stoichiometry: 1.0
species: 444671

536130
type: SpeciesReference
stoichiometry: 1.0
species: 445131

536021
type: SpeciesReference
stoichiometry: 12.0
species: 458685

536094
type: SpeciesReference
stoichiometry: 1.0
species: 457416

993626
type: Reaction
notes: R_DPMVDx subsystem: Cholesterol Metabolism R_DPMVDx equation: [x] : 5dpmev + atp --> adp + co2 + ipdp + pi
reactant: 529784
product: 529808
product: 529820
product: 529832
reversible: false
product: 529796
is: http://identifiers.org/ec-code/4.1.1.33
reactant: 529771
is: ENSBTAG00000012059.3
fast: false
name: diphosphomevalonate decarboxylase

529784
type: SpeciesReference
stoichiometry: 1.0
species: 450043

450043
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: ATP_C10H12N5O13P3

529808
type: SpeciesReference
stoichiometry: 1.0
species: 466820

529820
type: SpeciesReference
stoichiometry: 1.0
species: 448522

448522
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: ADP_C10H12N5O10P2

529832
type: SpeciesReference
stoichiometry: 1.0
species: 460522

460522
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Isopentenyl diphosphate_C5H9O7P2

529796
type: SpeciesReference
stoichiometry: 1.0
species: 451569

451569
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: CO2_CO2

529771
type: SpeciesReference
stoichiometry: 1.0
species: 446142

446142
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: (R)-5-Diphosphomevalonate_C6H10O10P2

471059
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Urate_C5H4N4O3

988742
type: Reaction
product: 485862
is: ENSBTAG00000016249.4
name: N-acteylglutamate synthase, mitochondrial
product: 485874
reactant: 485826
is: http://identifiers.org/ec-code/2.3.1.1
product: 485850
reactant: 485838
reversible: false
fast: false
notes: R_ACGSm subsystem: Urea cycle/amino group metabolism R_ACGSm equation: [m] : accoa + glu-L --> acglu + coa + h

485862
type: SpeciesReference
stoichiometry: 1.0
species: 451632

485874
type: SpeciesReference
stoichiometry: 1.0
species: 458843

485826
type: SpeciesReference
stoichiometry: 1.0
species: 447689

485850
type: SpeciesReference
stoichiometry: 1.0
species: 448052

485838
type: SpeciesReference
stoichiometry: 1.0
species: 457562

448922
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: _1-alkyl 2-lysoglycerol 3-phosphocholine_C10H21O5NPFULLR

994956
type: Reaction
product: 545346
reactant: 545334
notes: R_TPI subsystem: Glycolysis/Gluconeogenesis R_TPI equation: [c] : dhap <==> g3p
is: ENSBTAG00000019782.2
is: http://identifiers.org/ec-code/5.3.1.1
fast: false
reversible: true
name: triose-phosphate isomerase

545346
type: SpeciesReference
stoichiometry: 1.0
species: 456540

545334
type: SpeciesReference
stoichiometry: 1.0
species: 453650

460862
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 25_C118H192N8O98S4

991368
type: Reaction
reactant: 509304
is: ENSBTAG00000020902.4
fast: false
is: http://identifiers.org/ec-code/2.7.7.3
reversible: false
modifier: 509376
is: ENSBTAG00000030358.2
product: 509340
notes: R_PTPAT subsystem: CoA Biosynthesis R_PTPAT equation: [c] : atp + h + pan4p <==> dpcoa + ppi R_DPCOAK subsystem: CoA Biosynthesis R_DPCOAK equation: [c] : atp + dpcoa --> adp + coa + h
product: 509328
modifier: 509413
reactant: 509316
modifier: 509401
product: 509352
modifier: 509388
modifier: 509364
is: http://identifiers.org/ec-code/2.7.1.24

509304
type: SpeciesReference
stoichiometry: 1.0
species: 454571

454571
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Dephospho-CoA_C21H33N7O13P2S

509340
type: SpeciesReference
stoichiometry: 1.0
species: 448462

509328
type: SpeciesReference
stoichiometry: 1.0
species: 451593

509316
type: SpeciesReference
stoichiometry: 1.0
species: 449983

509352
type: SpeciesReference
stoichiometry: 1.0
species: 458794

448595
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: ADPribose_C15H21N5O14P2

447105
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: R total 2 carnitine_CO2FULLR2C7H14NO2

448196
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: N-Acetylneuraminate_C11H18NO9

459938
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: heparan sulfate, precursor 3_C45H69N2O36X

993602
type: Reaction
product: 529674
product: 529661
is: ENSBTAG00000039719.1
product: 529649
is: http://identifiers.org/ec-code/1.1.1.95
name: phosphoglycerate dehydrogenase
reversible: false
fast: false
reactant: 529637
notes: R_PGCD subsystem: Glycine, Serine, and Threonine Metabolism R_PGCD equation: [c] : 3pg + nad --> 3php + h + nadh
reactant: 529625

529674
type: SpeciesReference
stoichiometry: 1.0
species: 464590

529661
type: SpeciesReference
stoichiometry: 1.0
species: 458794

529649
type: SpeciesReference
stoichiometry: 1.0
species: 445335

529637
type: SpeciesReference
stoichiometry: 1.0
species: 445323

529625
type: SpeciesReference
stoichiometry: 1.0
species: 464518

990504
type: Reaction
notes: R_LCADim subsystem: Pyruvate Metabolism R_LCADim equation: [m] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDDm subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDDm equation: [m] : gcald + h2o + nad --> glyclt + (2) h + nadh R_SSALxm subsystem: Glutamate metabolism R_SSALxm equation: [m] : h2o + nad + sucsal --> (2) h + nadh + succ R_LCADi_Dm subsystem: Pyruvate Metabolism R_LCADi_Dm equation: [m] : h2o + lald-D + nad --> (2) h + lac-D + nadh
is: http://identifiers.org/ec-code/1.2.1.24
reactant: 500894
product: 500954
reactant: 500881
reactant: 500930
product: 500966
reactant: 500906
fast: false
product: 500978
product: 500942
reversible: false
product: 500991
is: ENSBTAG00000021902.4
product: 501003
reactant: 500869
reactant: 500918
is: http://identifiers.org/ec-code/1.2.1.21

500894
type: SpeciesReference
stoichiometry: 1.0
species: 462246

500954
type: SpeciesReference
stoichiometry: 1.0
species: 469190

500881
type: SpeciesReference
stoichiometry: 1.0
species: 462222

500930
type: SpeciesReference
stoichiometry: 1.0
species: 457043

500966
type: SpeciesReference
stoichiometry: 1.0
species: 462162

500906
type: SpeciesReference
stoichiometry: 4.0
species: 464542

500978
type: SpeciesReference
stoichiometry: 1.0
species: 462198

500942
type: SpeciesReference
stoichiometry: 1.0
species: 457900

500991
type: SpeciesReference
stoichiometry: 8.0
species: 458843

501003
type: SpeciesReference
stoichiometry: 4.0
species: 464602

500869
type: SpeciesReference
stoichiometry: 4.0
species: 458733

500918
type: SpeciesReference
stoichiometry: 1.0
species: 469250

469250
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Succinic semialdehyde_C4H5O3

467473
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: (13E)-11alpha-Hydroxy-9,15-dioxoprost-13-enoate_C20H31O5

995700
type: Reaction
modifier: 551334
reactant: 551043
modifier: 551309
product: 551213
reactant: 551031
product: 551165
reactant: 551055
product: 551189
is: http://identifiers.org/ec-code/1.2.1.39
product: 551079
product: 551128
is: http://identifiers.org/ec-code/1.2.1.3
notes: R_34DHXMANDACOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_34DHXMANDACOX_LPAREN_NADP_RPAREN_ equation: [c] : 34dhmald + h2o + nadp <==> 34dhoxmand + (2) h + nadph R_ALDD2y subsystem: Glycolysis/Gluconeogenesis R_ALDD2y equation: [c] : acald + h2o + nadp --> ac + (2) h + nadph R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD19x_LPAREN_P_RPAREN_ subsystem: Phenylalanine metabolism R_ALDD19x_LPAREN_P_RPAREN_ equation: [c] : h2o + nadp + pacald --> (2) h + nadph + pac R_34DHPLACOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_34DHPLACOX_LPAREN_NADP_RPAREN_ equation: [c] : 34dhpac + h2o + nadp <==> 34dhpha + (2) h + nadph R_3MOX4HOXPGALDOX subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX equation: [c] : 3m4hpga + h2o + nad --> 3mox4hoxm + (2) h + nadh R_MACOXO subsystem: Histidine Metabolism R_MACOXO equation: [c] : 3mldz + h2o + nad --> 3mlda + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_4HOXPACDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_4HOXPACDOX_LPAREN_NADP_RPAREN_ equation: [c] : 4hoxpacd + h2o + nadp <==> 4hphac + (2) h + nadph R_3M4HDXPAC subsystem: Tyrosine metabolism R_3M4HDXPAC equation: [c] : 3mox4hpac + h2o + nad <==> (2) h + homoval + nadh R_34DHPLACOX subsystem: Tyrosine metabolism R_34DHPLACOX equation: [c] : 34dhpac + h2o + nad --> 34dhpha + (2) h + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ equation: [c] : 3m4hpga + h2o + nadp <==> 3mox4hoxm + (2) h + nadph R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_ALDD19x subsystem: Phenylalanine metabolism R_ALDD19x equation: [c] : h2o + nad + pacald --> (2) h + nadh + pac R_GCALDD subsy…
reactant: 550935
is: ENSBTAG00000012054.4
modifier: 551297
modifier: 551321
modifier: 551395
fast: false
modifier: 551285
is: http://identifiers.org/ec-code/1.2.1.21
modifier: 551383
modifier: 551273
product: 551104
modifier: 551371
product: 551177
reactant: 550983
modifier: 551261
reactant: 551019
reactant: 550995
reactant: 551007
reactant: 550971
modifier: 551249
reactant: 550947
product: 551201
reactant: 551067
product: 551091
modifier: 551237
product: 551153
modifier: 551359
reactant: 550959
modifier: 551225
modifier: 551347
product: 551140
reversible: false
product: 551116
is: http://identifiers.org/ec-code/1.2.1.4
is: http://identifiers.org/ec-code/1.2.1.5
modifier: 551407

551043
type: SpeciesReference
stoichiometry: 12.0
species: 458685

551213
type: SpeciesReference
stoichiometry: 2.0
species: 464711

551031
type: SpeciesReference
stoichiometry: 2.0
species: 465913

551165
type: SpeciesReference
stoichiometry: 1.0
species: 462138

551055
type: SpeciesReference
stoichiometry: 1.0
species: 457332

551189
type: SpeciesReference
stoichiometry: 1.0
species: 445203

551079
type: SpeciesReference
stoichiometry: 1.0
species: 457888

551128
type: SpeciesReference
stoichiometry: 1.0
species: 445131

550935
type: SpeciesReference
stoichiometry: 1.0
species: 445143

551104
type: SpeciesReference
stoichiometry: 1.0
species: 457416

551177
type: SpeciesReference
stoichiometry: 23.0
species: 458794

550983
type: SpeciesReference
stoichiometry: 1.0
species: 444671

551019
type: SpeciesReference
stoichiometry: 2.0
species: 464639

550995
type: SpeciesReference
stoichiometry: 2.0
species: 447617

551007
type: SpeciesReference
stoichiometry: 1.0
species: 445095

550971
type: SpeciesReference
stoichiometry: 1.0
species: 457031

550947
type: SpeciesReference
stoichiometry: 1.0
species: 462234

551201
type: SpeciesReference
stoichiometry: 9.0
species: 464590

551067
type: SpeciesReference
stoichiometry: 1.0
species: 462210

551091
type: SpeciesReference
stoichiometry: 2.0
species: 447521

551153
type: SpeciesReference
stoichiometry: 1.0
species: 462174

550959
type: SpeciesReference
stoichiometry: 9.0
species: 464518

551140
type: SpeciesReference
stoichiometry: 2.0
species: 465901

551116
type: SpeciesReference
stoichiometry: 1.0
species: 444683

461811
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 3_C47H76N4O33X

449332
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: AMP_C10H12N5O7P

471239
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: vaccenyl coenzyme A_C39H64N7O17P3S

991512
type: Reaction
notes: R_H6_APOS_ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6_APOS_ETer equation: [r] : em3gacpail_hs + pe_hs --> dag_hs + em2emgacpail_hs R_H3ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3ETer equation: [r] : m2gacpail_hs + pe_hs --> dag_hs + memgacpail_hs R_H4ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H4ETer equation: [r] : m3gacpail_hs + pe_hs --> dag_hs + m2emgacpail_hs R_H7_APOS_ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7_APOS_ETer equation: [r] : emem2gacpail_hs + pe_hs --> dag_hs + gpi_hs R_H2ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H2ETer equation: [r] : mgacpail_hs + pe_hs --> dag_hs + emgacpail_hs
product: 510287
product: 510239
reversible: false
product: 510251
is: ENSBTAG00000016663.4
reactant: 510202
product: 510275
reactant: 510178
product: 510299
reactant: 510226
fast: false
reactant: 510166
reactant: 510190
reactant: 510214
product: 510263

510287
type: SpeciesReference
stoichiometry: 1.0
species: 463007

510239
type: SpeciesReference
stoichiometry: 1.0
species: 463709

510251
type: SpeciesReference
stoichiometry: 1.0
species: 455148

510202
type: SpeciesReference
stoichiometry: 1.0
species: 463019

510275
type: SpeciesReference
stoichiometry: 5.0
species: 452987

452987
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2

510178
type: SpeciesReference
stoichiometry: 1.0
species: 463069

510299
type: SpeciesReference
stoichiometry: 1.0
species: 455196

510226
type: SpeciesReference
stoichiometry: 1.0
species: 463903

510166
type: SpeciesReference
stoichiometry: 1.0
species: 455172

455172
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: phosphoethanolaminyl-trimannosyl-glucosaminyl-acylphosphatidylinositol (H6')_C51H94N2O32P2FULLRCO2FULLR2CO2

510190
type: SpeciesReference
stoichiometry: 1.0
species: 455184

455184
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: (phosphoethanolaminyl-mannosyl),(phosphoethanolaminyl)-dimannosyl-glucosaminyl-acylphosphatidylinositol (H7')_C53H100N3O35P3FULLRCO2FULLR2CO2

510214
type: SpeciesReference
stoichiometry: 5.0
species: 466423

466423
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2

510263
type: SpeciesReference
stoichiometry: 1.0
species: 458191

997471
type: Reaction
reactant: 569455
product: 569516
product: 569552
product: 569504
product: 569540
notes: R_NTD5 subsystem: Pyrimidine Catabolism R_NTD5 equation: [c] : dtmp + h2o --> pi + thymd R_NTD1 subsystem: Pyrimidine Catabolism R_NTD1 equation: [c] : dump + h2o --> duri + pi R_NTD3 subsystem: Pyrimidine Catabolism R_NTD3 equation: [c] : dcmp + h2o --> dcyt + pi R_NTD8 subsystem: Nucleotides R_NTD8 equation: [c] : dgmp + h2o --> dgsn + pi R_NTD12 subsystem: Nucleotides R_NTD12 equation: [c] : dimp + h2o --> din + pi
reactant: 569416
product: 569492
fast: false
product: 569528
reactant: 569480
reactant: 569468
is: http://identifiers.org/ec-code/3.1.3.5
reversible: false
reactant: 569442
is: ENSBTAG00000011527.3
reactant: 569429

569455
type: SpeciesReference
stoichiometry: 1.0
species: 454691

569516
type: SpeciesReference
stoichiometry: 5.0
species: 466736

569552
type: SpeciesReference
stoichiometry: 1.0
species: 453566

569504
type: SpeciesReference
stoichiometry: 1.0
species: 454050

454050
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Deoxyinosine_C10H12N4O4

569540
type: SpeciesReference
stoichiometry: 1.0
species: 453288

453288
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Deoxycytidine_C9H13N3O4

569416
type: SpeciesReference
stoichiometry: 1.0
species: 453518

453518
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dGMP_C10H12N5O7P

569492
type: SpeciesReference
stoichiometry: 1.0
species: 454860

569528
type: SpeciesReference
stoichiometry: 1.0
species: 470071

569480
type: SpeciesReference
stoichiometry: 1.0
species: 453144

569468
type: SpeciesReference
stoichiometry: 5.0
species: 458685

569442
type: SpeciesReference
stoichiometry: 1.0
species: 454824

569429
type: SpeciesReference
stoichiometry: 1.0
species: 454038

454038
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: dIMP_C10H11N4O7P

990204
type: Reaction
reactant: 498538
modifier: 498694
reversible: false
product: 498598
modifier: 498634
product: 498586
fast: false
is: http://identifiers.org/ec-code/3.5.2.3
reactant: 498550
modifier: 498658
modifier: 498682
reactant: 498562
reactant: 498526
is: http://identifiers.org/ec-code/2.1.3.2
notes: R_CBPS subsystem: Pyrimidine Biosynthesis R_CBPS equation: [c] : (2) atp + gln-L + h2o + hco3 --> (2) adp + cbp + glu-L + (2) h + pi R_ASPCTr subsystem: Pyrimidine Biosynthesis R_ASPCTr equation: [c] : asp-L + cbp <==> cbasp + h + pi R_DHORTS subsystem: Pyrimidine Biosynthesis R_DHORTS equation: [c] : dhor-S + h2o <==> cbasp + h
product: 498574
is: http://identifiers.org/ec-code/6.3.5.5
modifier: 498646
product: 498622
modifier: 498706
is: ENSBTAG00000003457.4
modifier: 498670
product: 498610

498538
type: SpeciesReference
stoichiometry: 1.0
species: 457464

498598
type: SpeciesReference
stoichiometry: 2.0
species: 448462

453953
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: (S)-Dihydroorotate_C5H5N2O4

498586
type: SpeciesReference
stoichiometry: 1.0
species: 457525

498550
type: SpeciesReference
stoichiometry: 2.0
species: 449983

450647
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Carbamoyl-L-aspartate_C5H6N2O5

498562
type: SpeciesReference
stoichiometry: 1.0
species: 458685

498526
type: SpeciesReference
stoichiometry: 1.0
species: 458952

498574
type: SpeciesReference
stoichiometry: 1.0
species: 466736

450695
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Carbamoyl phosphate_CH2NO5P

498622
type: SpeciesReference
stoichiometry: 2.0
species: 458794

498610
type: SpeciesReference
stoichiometry: 1.0
species: 450695

996049
type: Reaction
is: http://identifiers.org/ec-code/4.3.1.3
reversible: false
fast: false
product: 555516
name: histidase
is: ENSBTAG00000016276.4
product: 555504
notes: R_HISD subsystem: Histidine Metabolism R_HISD equation: [c] : his-L --> nh4 + urcan
reactant: 555492

555516
type: SpeciesReference
stoichiometry: 1.0
species: 464834

555504
type: SpeciesReference
stoichiometry: 1.0
species: 471071

555492
type: SpeciesReference
stoichiometry: 1.0
species: 459289

993650
type: Reaction
is: ENSBTAG00000013585.4
is: ENSBTAG00000007646.4
notes: R_PIACGT subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_PIACGT equation: [c] : pail_hs + uacgam --> acgpail_hs + h + udp
is: ENSBTAG00000024542.1
is: ENSBTAG00000018299.2
is: http://identifiers.org/ec-code/2.4.1.198
is: ENSBTAG00000034569.1
is: ENSBTAG00000011512.3
reversible: false
product: 530072
fast: false
is: ENSBTAG00000016594.4
name: phosphatidylinositol N-acetylglucosaminyltransferase
reactant: 530024
is: ENSBTAG00000024623.3
reactant: 530036
product: 530048
product: 530060

530072
type: SpeciesReference
stoichiometry: 1.0
species: 458794

530024
type: SpeciesReference
stoichiometry: 1.0
species: 466130

530036
type: SpeciesReference
stoichiometry: 1.0
species: 470640

530048
type: SpeciesReference
stoichiometry: 1.0
species: 470664

530060
type: SpeciesReference
stoichiometry: 1.0
species: 448064

448064
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610

466214
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3'-Phosphoadenylyl sulfate_C10H11N5O13P2S

W3 CDTF: Fri Feb 03 12:44:18 GMT 2012

461213
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 11_C129H208N9O101S3X

994377
type: Reaction
product: 538030
product: 538054
is: ENSBTAG00000007787.3
reversible: false
is: http://identifiers.org/ec-code/3.1.2.4
product: 538042
reactant: 538006
notes: R_3HPCOAHYD subsystem: beta-Alanine metabolism R_3HPCOAHYD equation: [c] : 3hpcoa + h2o --> 3hpp + coa + h
name: _3-hydroxyisobutyryl-Coenzyme A hydrolase
reactant: 538018
fast: false

538030
type: SpeciesReference
stoichiometry: 1.0
species: 451593

538054
type: SpeciesReference
stoichiometry: 1.0
species: 458794

538042
type: SpeciesReference
stoichiometry: 1.0
species: 445035

445035
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Hydroxypropanoate_C3H5O3

538006
type: SpeciesReference
stoichiometry: 1.0
species: 444999

444999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Hydroxypropionyl-CoA_C24H36N7O18P3S

538018
type: SpeciesReference
stoichiometry: 1.0
species: 458685

998120
type: Reaction
product: 574991
is: ENSBTAG00000001325.4
reactant: 574943
product: 574979
product: 574955
product: 574967
fast: false
reversible: false
reactant: 574907
reactant: 574931
notes: R_BUP2 subsystem: Pyrimidine Catabolism R_BUP2 equation: [c] : 3uib + (2) h + h2o --> 3aib-D + co2 + nh4 R_UPPN subsystem: Pyrimidine Catabolism R_UPPN equation: [c] : cala + (2) h + h2o --> ala-B + co2 + nh4
reactant: 574919
is: http://identifiers.org/ec-code/3.5.1.6

574991
type: SpeciesReference
stoichiometry: 1.0
species: 444805

574943
type: SpeciesReference
stoichiometry: 4.0
species: 458794

574979
type: SpeciesReference
stoichiometry: 1.0
species: 449006

574955
type: SpeciesReference
stoichiometry: 2.0
species: 464834

574967
type: SpeciesReference
stoichiometry: 2.0
species: 451519

574907
type: SpeciesReference
stoichiometry: 1.0
species: 450563

574931
type: SpeciesReference
stoichiometry: 2.0
species: 458685

574919
type: SpeciesReference
stoichiometry: 1.0
species: 445420

445420
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _3-Ureidoisobutyrate_C5H9N2O3

994980
type: Reaction
reactant: 545455
product: 545528
product: 545467
is: ENSBTAG00000005479.4
reactant: 545443
fast: false
product: 545492
is: http://identifiers.org/ec-code/3.1.1.23
reversible: false
product: 545540
product: 545516
product: 545504
notes: R_LPSe subsystem: Triacylglycerol Synthesis R_LPSe equation: [e] : h2o + tag_hs --> Rtotal3 + dag_hs + h R_LPS2e subsystem: Fatty Acid Metabolism R_LPS2e equation: [e] : dag_hs + h2o --> Rtotal + h + mag_hs R_LPS3e subsystem: Fatty Acid Metabolism R_LPS3e equation: [e] : h2o + mag_hs --> Rtotal2 + glyc + h
reactant: 545419
reactant: 545431
is: http://identifiers.org/ec-code/3.1.1.3
product: 545479

545455
type: SpeciesReference
stoichiometry: 3.0
species: 458697

545528
type: SpeciesReference
stoichiometry: 1.0
species: 447214

447214
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: R total_CO2FULLR

545467
type: SpeciesReference
stoichiometry: 3.0
species: 458806

545443
type: SpeciesReference
stoichiometry: 1.0
species: 469310

545492
type: SpeciesReference
stoichiometry: 1.0
species: 463407

545540
type: SpeciesReference
stoichiometry: 1.0
species: 447069

447069
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: R total 2 position_CO2FULLR2

545516
type: SpeciesReference
stoichiometry: 1.0
species: 457864

457864
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Glycerol_C3H8O3

545504
type: SpeciesReference
stoichiometry: 1.0
species: 452963

545419
type: SpeciesReference
stoichiometry: 1.0
species: 463407

545431
type: SpeciesReference
stoichiometry: 1.0
species: 452963

545479
type: SpeciesReference
stoichiometry: 1.0
species: 447141

998012
type: Reaction
notes: R_CPPPGO subsystem: Heme Biosynthesis R_CPPPGO equation: [c] : cpppg3 + (2) h + o2 --> (2) co2 + (2) h2o + pppg9
reactant: 573954
fast: false
product: 574002
reversible: false
reactant: 573966
product: 574014
is: http://identifiers.org/ec-code/1.3.3.3
is: ENSBTAG00000004124.4
product: 573990
reactant: 573978
name: coproporphyrinogen oxidase (O2 required)

573954
type: SpeciesReference
stoichiometry: 1.0
species: 451780

451780
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Coproporphyrinogen III_C36H40N4O8

574002
type: SpeciesReference
stoichiometry: 2.0
species: 451519

573966
type: SpeciesReference
stoichiometry: 1.0
species: 465234

574014
type: SpeciesReference
stoichiometry: 2.0
species: 458685

573990
type: SpeciesReference
stoichiometry: 1.0
species: 467122

467122
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Protoporphyrinogen IX_C34H38N4O4

573978
type: SpeciesReference
stoichiometry: 2.0
species: 458794

997718
type: Reaction
product: 571852
fast: false
product: 571840
reactant: 571804
notes: R_GK1 subsystem: Nucleotides R_GK1 equation: [c] : atp + gmp <==> adp + gdp R_DGK1 subsystem: Nucleotides R_DGK1 equation: [c] : atp + dgmp <==> adp + dgdp
reactant: 571792
product: 571828
reversible: true
reactant: 571816
is: ENSBTAG00000014775.4
is: http://identifiers.org/ec-code/2.7.4.8

571852
type: SpeciesReference
stoichiometry: 1.0
species: 453482

571840
type: SpeciesReference
stoichiometry: 2.0
species: 448462

571804
type: SpeciesReference
stoichiometry: 1.0
species: 458070

571792
type: SpeciesReference
stoichiometry: 1.0
species: 453518

571828
type: SpeciesReference
stoichiometry: 1.0
species: 457199

571816
type: SpeciesReference
stoichiometry: 2.0
species: 449983

461347
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 21_C177H284N12O145S6X

987541
type: Reaction
product: 474188
reactant: 474176
notes: R_PGISr subsystem: Eicosanoid Metabolism R_PGISr equation: [r] : prostgh2 <==> prostgi2
is: ENSBTAG00000017537.4
is: http://identifiers.org/ec-code/5.3.99.4
fast: false
reversible: true
name: Prostaglandin I2 synthase

474188
type: SpeciesReference
stoichiometry: 1.0
species: 467632

467632
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Prostaglandin I2_C20H31O5

474176
type: SpeciesReference
stoichiometry: 1.0
species: 467620

996061
type: Reaction
reactant: 555541
is: ENSBTAG00000003108.3
reactant: 555589
reactant: 555565
fast: false
product: 555601
product: 555637
reversible: false
is: http://identifiers.org/ec-code/2.4.1.133
notes: R_SR5ARr subsystem: Steroid Metabolism R_SR5ARr equation: [r] : h + nadph + tststerone --> 5adtststerone + nadp R_GALTg subsystem: Chondroitin / heparan sulfate biosynthesis R_GALTg equation: [g] : udpgal + xser --> h + lxser + udp R_SR5AR2r subsystem: Steroid Metabolism R_SR5AR2r equation: [r] : andrstndn + h + nadph --> andrstandn + nadp
is: http://identifiers.org/ec-code/1.3.99.5
product: 555625
reactant: 555528
product: 555613
product: 555649
product: 555661
reactant: 555553
reactant: 555577

555541
type: SpeciesReference
stoichiometry: 2.0
species: 464747

555589
type: SpeciesReference
stoichiometry: 2.0
species: 458867

555565
type: SpeciesReference
stoichiometry: 1.0
species: 449393

555601
type: SpeciesReference
stoichiometry: 1.0
species: 470688

555637
type: SpeciesReference
stoichiometry: 1.0
species: 449381

555625
type: SpeciesReference
stoichiometry: 1.0
species: 462923

555528
type: SpeciesReference
stoichiometry: 1.0
species: 471733

555613
type: SpeciesReference
stoichiometry: 1.0
species: 458819

555649
type: SpeciesReference
stoichiometry: 2.0
species: 464687

555661
type: SpeciesReference
stoichiometry: 1.0
species: 445998

555553
type: SpeciesReference
stoichiometry: 1.0
species: 470409

555577
type: SpeciesReference
stoichiometry: 1.0
species: 470848

447177
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: R total 3 carnitine_CO2FULLR3C7H14NO2

446732
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: heptaglutamyl folate (THF)_C49H57N13O24

991921
type: Reaction
product: 513736
reactant: 513458
reactant: 513543
reactant: 513603
reactant: 513555
reactant: 513591
is: http://identifiers.org/ec-code/2.4.1.149
product: 513832
reactant: 513483
is: ENSBTAG00000034514.2
fast: false
product: 513917
reactant: 513615
reactant: 513422
reactant: 513567
product: 513712
reactant: 513507
product: 513687
is: ENSBTAG00000018046.4
reactant: 513519
product: 513892
product: 513748
reactant: 513531
product: 513724
reactant: 513434
product: 513796
product: 513772
reversible: false
reactant: 513446
reactant: 513651
product: 513868
product: 513820
product: 513905
notes: R_B3GNT11g subsystem: Blood Group Biosynthesis R_B3GNT11g equation: [g] : gal14acglcgalgluside_hs + uacgam --> acglcgal14acglcgalgluside_hs + h + udp R_AG13T6g subsystem: Keratan sulfate biosynthesis R_AG13T6g equation: [g] : ksi_pre6 + uacgam --> h + ksi_pre7 + udp R_AG13T17g subsystem: Keratan sulfate biosynthesis R_AG13T17g equation: [g] : ksii_core4_pre4 + uacgam --> h + ksii_core4_pre5 + udp R_B3GNT12g subsystem: Blood Group Biosynthesis R_B3GNT12g equation: [g] : galacglcgal14acglcgalgluside_hs + uacgam --> acglc13galacglcgal14acglcgalgluside_hs + h + udp R_AG13T2g subsystem: Keratan sulfate biosynthesis R_AG13T2g equation: [g] : ksii_core2_pre4 + uacgam --> h + ksii_core2_pre5 + udp R_AG13T5g subsystem: Keratan sulfate biosynthesis R_AG13T5g equation: [g] : ksi_pre3 + uacgam --> h + ksi_pre4 + udp R_AG13T8g subsystem: Keratan sulfate biosynthesis R_AG13T8g equation: [g] : ksi_pre12 + uacgam --> h + ksi_pre13 + udp R_AG13T12g subsystem: Keratan sulfate biosynthesis R_AG13T12g equation: [g] : ksi_pre24 + uacgam --> h + ksi_pre25 + udp R_AG13T1g subsystem: Keratan sulfate biosynthesis R_AG13T1g equation: [g] : ksii_core2_pre2 + uacgam --> h + ksii_core2_pre3 + udp R_AG13T10g subsystem: Keratan sulfate biosynthesis R_AG13T10g equation: [g] : ksi_pre18 + uacgam --> h + ksi_pre19 + udp R_AG13T14g subsystem: Keratan sulfate biosynthesis R_AG13T14g equation: [g] : ksi_pre30 + uacgam --> h + ksi_pre31 + udp R_AG13T13g subsystem: Keratan sulfate biosynthesis R_AG13T13g equation: [g] : ksi_pre27 + uacgam --> h + ksi_pre28 + udp R_AG13T9g subsystem: Keratan sulfate biosynthesis R_AG13T9g equation: [g] : ksi_pre15 + uacgam --> h + ksi_pre16 + udp R_AG13T15g subsystem: Keratan sulfate biosynthesis R_AG13T15g equation: [g] : ksi_pre33 + uacgam --> h + ksi_pre34 + udp R_AG13T4g subsystem: Keratan sulfate biosynthesis R_AG13T4g equation: [g] : ksi_pre1 + uacgam --> h + ksi_pre2 + udp R_AG13T11g subsystem: Keratan sulfate biosynthesis R_AG13T11g equation: [g] : ksi_pre21 + uac…
product: 513808
reactant: 513627
reactant: 513579
product: 513675
product: 513880
reactant: 513471
product: 513844
product: 513784
product: 513929
reactant: 513639
product: 513760
reactant: 513495
product: 513856
reactant: 513663
product: 513699

513736
type: SpeciesReference
stoichiometry: 1.0
species: 461600

461600
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 7_C115H187N8O85SX

513458
type: SpeciesReference
stoichiometry: 1.0
species: 461552

461552
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 3_C93H152N6O67X

513543
type: SpeciesReference
stoichiometry: 1.0
species: 461625

461625
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 9_C121H196N8O93S2X

513603
type: SpeciesReference
stoichiometry: 1.0
species: 461994

513555
type: SpeciesReference
stoichiometry: 1.0
species: 461298

461298
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 18_C163H262N11O132S5X

513591
type: SpeciesReference
stoichiometry: 1.0
species: 461799

461799
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 2_C39H63N3O28X

513832
type: SpeciesReference
stoichiometry: 1.0
species: 461455

513483
type: SpeciesReference
stoichiometry: 1.0
species: 461383

461383
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 24_C191H306N13O158S7X

513917
type: SpeciesReference
stoichiometry: 1.0
species: 461274

513615
type: SpeciesReference
stoichiometry: 1.0
species: 462018

462018
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 4_C61H99N5O43X

513422
type: SpeciesReference
stoichiometry: 1.0
species: 461467

461467
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 30_C219H350N15O184S9X

513567
type: SpeciesReference
stoichiometry: 1.0
species: 461859

461859
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 7_C67H108N5O51SX

513712
type: SpeciesReference
stoichiometry: 1.0
species: 461479

461479
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 31_C227H363N16O189S9X

513507
type: SpeciesReference
stoichiometry: 1.0
species: 461323

461323
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 1_C79H129N5O57X

513687
type: SpeciesReference
stoichiometry: 1.0
species: 461395

461395
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 25_C199H319N14O163S7X

513519
type: SpeciesReference
stoichiometry: 20.0
species: 470652

513892
type: SpeciesReference
stoichiometry: 1.0
species: 462030

462030
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 5_C69H112N6O48X

513748
type: SpeciesReference
stoichiometry: 20.0
species: 470688

513531
type: SpeciesReference
stoichiometry: 1.0
species: 461503

461503
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 33_C233H372N16O197S10X

513724
type: SpeciesReference
stoichiometry: 1.0
species: 461431

513434
type: SpeciesReference
stoichiometry: 1.0
species: 456641

513796
type: SpeciesReference
stoichiometry: 1.0
species: 461835

461835
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 5_C61H99N5O43X

513772
type: SpeciesReference
stoichiometry: 1.0
species: 461201

461201
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 10_C129H209N9O98S2X

513446
type: SpeciesReference
stoichiometry: 1.0
species: 461419

461419
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 27_C205H328N14O171S8X

513651
type: SpeciesReference
stoichiometry: 1.0
species: 461588

461588
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 6_C107H174N7O80SX

513868
type: SpeciesReference
stoichiometry: 1.0
species: 461238

461238
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 13_C143H231N10O111S3X

513820
type: SpeciesReference
stoichiometry: 1.0
species: 461359

513905
type: SpeciesReference
stoichiometry: 1.0
species: 461516

513808
type: SpeciesReference
stoichiometry: 1.0
species: 461871

461871
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 8_C75H121N6O56SX

513627
type: SpeciesReference
stoichiometry: 1.0
species: 456737

513579
type: SpeciesReference
stoichiometry: 1.0
species: 461262

513675
type: SpeciesReference
stoichiometry: 1.0
species: 462006

462006
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 3_C55H89N5O38X

513880
type: SpeciesReference
stoichiometry: 1.0
species: 461564

461564
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 4_C101H165N7O72X

513471
type: SpeciesReference
stoichiometry: 1.0
species: 462054

462054
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 7_C75H121N6O56SX

513844
type: SpeciesReference
stoichiometry: 1.0
species: 447992

447992
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: nLc7Cer_C66H115N4O37FULLRCO

513784
type: SpeciesReference
stoichiometry: 1.0
species: 448004

448004
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: nLc5Cer_C52H92N3O27FULLRCO

513929
type: SpeciesReference
stoichiometry: 1.0
species: 461310

461310
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 19_C171H275N12O137S5X

513639
type: SpeciesReference
stoichiometry: 1.0
species: 461823

513760
type: SpeciesReference
stoichiometry: 20.0
species: 458819

513495
type: SpeciesReference
stoichiometry: 1.0
species: 461225

513856
type: SpeciesReference
stoichiometry: 1.0
species: 461811

513663
type: SpeciesReference
stoichiometry: 1.0
species: 461347

513699
type: SpeciesReference
stoichiometry: 1.0
species: 462066

462066
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 8_C83H134N7O61SX

460911
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 29_C96H157N6O80S3

997146
type: Reaction
fast: false
reversible: false
product: 564799
is: ENSBTAG00000012403.4
reactant: 564786
product: 564812
name: arginase
is: http://identifiers.org/ec-code/3.5.3.1
reactant: 564774
notes: R_ARGN subsystem: Urea cycle/amino group metabolism R_ARGN equation: [c] : arg-L + h2o --> orn + urea

564799
type: SpeciesReference
stoichiometry: 1.0
species: 465743

564786
type: SpeciesReference
stoichiometry: 1.0
species: 458685

564812
type: SpeciesReference
stoichiometry: 1.0
species: 471083

564774
type: SpeciesReference
stoichiometry: 1.0
species: 449801

449801
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Arginine_C6H15N4O2

467437
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: L-Proline_C5H9NO2

997523
type: Reaction
product: 569961
reactant: 569925
reactant: 569889
is: ENSBTAG00000011620.4
is: ENSBTAG00000013098.4
is: ENSBTAG00000031012.2
reactant: 569937
notes: R_M4BTAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4BTAer equation: [r] : mem2emgacpail_hs + pre_prot --> gpi_sig + mem2emgacpail_prot_hs R_H8TAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8TAer equation: [r] : gpi_hs + pre_prot --> gpi_prot_hs + gpi_sig R_M4ATAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4ATAer equation: [r] : m(em)3gacpail_hs + pre_prot --> gpi_sig + m(em)3gacpail_prot_hs R_H7_APOS_TAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7_APOS_TAer equation: [r] : em2emgacpail_hs + pre_prot --> em2emgacpail_prot_hs + gpi_sig
reversible: false
reactant: 569913
reactant: 569901
product: 569949
product: 569997
is: ENSBTAG00000014610.3
product: 569985
fast: false
product: 569973

569961
type: SpeciesReference
stoichiometry: 1.0
species: 458203

569925
type: SpeciesReference
stoichiometry: 1.0
species: 458191

569889
type: SpeciesReference
stoichiometry: 1.0
species: 463371

463371
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: mannosyl-3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol (M4A)_C61H116N4O43P4FULLRCO2FULLR2CO2

569937
type: SpeciesReference
stoichiometry: 1.0
species: 463685

569913
type: SpeciesReference
stoichiometry: 4.0
species: 467195

569901
type: SpeciesReference
stoichiometry: 1.0
species: 455148

569949
type: SpeciesReference
stoichiometry: 4.0
species: 458215

569997
type: SpeciesReference
stoichiometry: 1.0
species: 463697

569985
type: SpeciesReference
stoichiometry: 1.0
species: 463383

463383
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: mannosyl-3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol-Protein (M4A)_C61H116N4O43P4FULLRCO2FULLR2CO2X

569973
type: SpeciesReference
stoichiometry: 1.0
species: 455160

995376
type: Reaction
notes: R_PSP_L subsystem: Glycine, Serine, and Threonine Metabolism R_PSP_L equation: [c] : h2o + pser-L --> pi + ser-L
product: 548718
name: phosphoserine phosphatase (L-serine)
reactant: 548681
is: ENSBTAG00000013081.3
reactant: 548693
fast: false
is: http://identifiers.org/ec-code/3.1.3.3
reversible: false
product: 548705

548718
type: SpeciesReference
stoichiometry: 1.0
species: 466736

548681
type: SpeciesReference
stoichiometry: 1.0
species: 467716

548693
type: SpeciesReference
stoichiometry: 1.0
species: 458685

548705
type: SpeciesReference
stoichiometry: 1.0
species: 468623

453808
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Dehydroepiandrosterone_C19H28O2

463479
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Malonyl-CoA_C24H33N7O19P3S

454343
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Deamino-NAD+_C21H24N6O15P2

991068
type: Reaction
product: 506060
product: 506047
notes: R_ARSA subsystem: Sphingolipid Metabolism R_ARSA equation: [l] : h2o + sgalside_hs --> galside_hs + h + so4
name: Arylsulfatase A
fast: false
reactant: 506023
reversible: false
is: http://identifiers.org/ec-code/3.1.6.8
product: 506035
reactant: 506011
is: ENSBTAG00000016053.4

506060
type: SpeciesReference
stoichiometry: 1.0
species: 456921

506047
type: SpeciesReference
stoichiometry: 1.0
species: 458831

506023
type: SpeciesReference
stoichiometry: 1.0
species: 458721

506035
type: SpeciesReference
stoichiometry: 1.0
species: 468767

468767
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Sulfate_O4S

506011
type: SpeciesReference
stoichiometry: 1.0
species: 468683

458046
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GM2alpha (homo sapiens)_C49H85N3O25FULLRCO

468671
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: sulfatide galactocerebroside (homo sapiens)_C24H45NO10SFULLRCO

446490
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: haxglutamyl folate (DHF)_C44H49N12O21

446708
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: heptaglutamyl folate (THF)_C49H57N13O24

988670
type: Reaction
product: 484751
fast: false
reversible: false
is: ENSBTAG00000012380.4
product: 484738
is: ENSBTAG00000013108.4
reactant: 484690
is: http://identifiers.org/ec-code/2.7.1.7
is: ENSBTAG00000002067.3
reactant: 484714
product: 484799
reactant: 484726
is: ENSBTAG00000033398.2
product: 484787
notes: R_HEX10 subsystem: Aminosugar Metabolism R_HEX10 equation: [c] : atp + gam --> adp + gam6p + h R_HEX4 subsystem: Fructose and Mannose Metabolism R_HEX4 equation: [c] : atp + man --> adp + h + man6p R_HEX7 subsystem: Fructose and Mannose Metabolism R_HEX7 equation: [c] : atp + fru --> adp + f6p + h R_HEX1 subsystem: Glycolysis/Gluconeogenesis R_HEX1 equation: [c] : atp + glc-D --> adp + g6p + h
is: ENSBTAG00000033651.2
is: ENSBTAG00000032288.2
product: 484775
is: ENSBTAG00000014898.4
reactant: 484678
reactant: 484702
product: 484763
is: http://identifiers.org/ec-code/2.7.1.1

484751
type: SpeciesReference
stoichiometry: 1.0
species: 456566

484738
type: SpeciesReference
stoichiometry: 1.0
species: 456958

456958
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Glucosamine 6-phosphate_C6H13NO8P

484690
type: SpeciesReference
stoichiometry: 1.0
species: 463599

463599
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Mannose_C6H12O6

484714
type: SpeciesReference
stoichiometry: 1.0
species: 456970

456970
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-Glucosamine_C6H14NO5

484799
type: SpeciesReference
stoichiometry: 4.0
species: 458794

484726
type: SpeciesReference
stoichiometry: 1.0
species: 457356

484787
type: SpeciesReference
stoichiometry: 1.0
species: 463587

484775
type: SpeciesReference
stoichiometry: 1.0
species: 455546

484678
type: SpeciesReference
stoichiometry: 4.0
species: 449983

484702
type: SpeciesReference
stoichiometry: 1.0
species: 456004

484763
type: SpeciesReference
stoichiometry: 4.0
species: 448462

996603
type: Reaction
fast: false
reactant: 560374
is: http://identifiers.org/ec-code/6.4.1.2
reactant: 560399
name: acetyl-CoA carboxylase
product: 560423
reversible: false
product: 560435
is: ENSBTAG00000022055.3
reactant: 560386
is: ENSBTAG00000017567.4
product: 560411
notes: R_ACCOAC subsystem: Fatty Acid Metabolism R_ACCOAC equation: [c] : accoa + atp + hco3 --> adp + h + malcoa + pi
product: 560447

560374
type: SpeciesReference
stoichiometry: 1.0
species: 458952

560399
type: SpeciesReference
stoichiometry: 1.0
species: 447665

560423
type: SpeciesReference
stoichiometry: 1.0
species: 463467

463467
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Malonyl-CoA_C24H33N7O19P3S

560435
type: SpeciesReference
stoichiometry: 1.0
species: 448462

560386
type: SpeciesReference
stoichiometry: 1.0
species: 449983

560411
type: SpeciesReference
stoichiometry: 1.0
species: 466736

560447
type: SpeciesReference
stoichiometry: 1.0
species: 458794

ORG:
  orgname: University of Missouri - Columbia
n:
  given: Conant
  family: Conant

454607
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: disialyl-T antigen_C36H56N3O26X

456982
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: D-Glucosamine_C6H14NO5

995976
type: Reaction
name: Dopachrome tautomerase
fast: false
reactant: 554005
is: ENSBTAG00000024960.3
is: ENSBTAG00000026180.3
is: ENSBTAG00000038065.1
is: ENSBTAG00000039189.1
is: ENSBTAG00000009421.4
reversible: true
is: ENSBTAG00000010628.4
is: ENSBTAG00000038426.1
is: ENSBTAG00000019259.4
is: ENSBTAG00000039366.1
is: ENSBTAG00000022893.2
is: ENSBTAG00000009640.3
is: http://identifiers.org/ec-code/5.3.3.12
product: 554018
is: ENSBTAG00000038366.1
is: ENSBTAG00000038263.1
is: ENSBTAG00000039993.1
notes: R_DCT subsystem: Tyrosine metabolism R_DCT equation: [c] : L-dpchrm <==> 56dihindlcrbxlt
is: ENSBTAG00000024959.3
is: ENSBTAG00000000963.4

554005
type: SpeciesReference
stoichiometry: 1.0
species: 446840

446840
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Dopachrome_C9H6NO4

554018
type: SpeciesReference
stoichiometry: 1.0
species: 445926

455040
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: ecgonine methyl ester_C10H17NO3

443743
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19

449705
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: arachidonic acid_C20H31O2

448304
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: O-Acetylcarnitine_C9H17NO4

993229
type: Reaction
reactant: 526662
fast: false
notes: R_M13N4Tg subsystem: N-Glycan Biosynthesis R_M13N4Tg equation: [g] : n2m2masn + uacgam --> h + n3m2masn + udp
name: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
is: ENSBTAG00000010388.4
reactant: 526650
is: ENSBTAG00000009738.4
product: 526698
is: http://identifiers.org/ec-code/2.4.1.145
product: 526686
product: 526674
reversible: false

526662
type: SpeciesReference
stoichiometry: 1.0
species: 470652

526650
type: SpeciesReference
stoichiometry: 1.0
species: 464314

526698
type: SpeciesReference
stoichiometry: 1.0
species: 464410

526686
type: SpeciesReference
stoichiometry: 1.0
species: 458819

526674
type: SpeciesReference
stoichiometry: 1.0
species: 470688

992485
type: Reaction
product: 519842
reactant: 519829
notes: R_DCIm subsystem: Fatty Acid Metabolism R_DCIm equation: [m] : dd2coa <==> dd3coa
is: ENSBTAG00000009965.3
is: http://identifiers.org/ec-code/5.3.3.8
fast: false
reversible: true
name: dodecenoyl-Coenzyme A delta isomerase

519842
type: SpeciesReference
stoichiometry: 1.0
species: 453336

453336
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _3-dodecenoyl CoA_C33H52N7O17P3S

519829
type: SpeciesReference
stoichiometry: 1.0
species: 453324

467849
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Pyridoxal 5'-phosphate_C8H8NO6P

994559
type: Reaction
reactant: 540827
product: 540888
fast: false
product: 540876
reversible: false
is: http://identifiers.org/ec-code/2.8.2.11
reactant: 540852
notes: R_GAL3ST11 subsystem: Sphingolipid Metabolism R_GAL3ST11 equation: [g] : galside_hs + paps --> h + pap + sgalside_hs R_GAL3ST12 subsystem: Sphingolipid Metabolism R_GAL3ST12 equation: [g] : digalside_hs + paps --> digalsgalside_hs + h + pap
product: 540864
is: ENSBTAG00000014232.4
reactant: 540840
product: 540901

540827
type: SpeciesReference
stoichiometry: 1.0
species: 456909

540888
type: SpeciesReference
stoichiometry: 1.0
species: 468671

540876
type: SpeciesReference
stoichiometry: 2.0
species: 458819

540852
type: SpeciesReference
stoichiometry: 1.0
species: 454013

454013
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Digalactosylceramide_C30H56NO12FULLRCO

540864
type: SpeciesReference
stoichiometry: 1.0
species: 454001

454001
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646

540840
type: SpeciesReference
stoichiometry: 2.0
species: 466226

540901
type: SpeciesReference
stoichiometry: 2.0
species: 466202

997892
type: Reaction
is: ENSBTAG00000020499.4
product: 572948
reactant: 572936
reactant: 572924
fast: false
is: http://identifiers.org/ec-code/3.1.1.4
is: ENSBTAG00000039122.1
reversible: false
is: ENSBTAG00000004418.3
is: ENSBTAG00000026732.2
name: phospholipase A2
product: 572960
is: ENSBTAG00000021522.4
notes: R_PLA2_2e subsystem: Glycerophospholipid Metabolism R_PLA2_2e equation: [e] : h2o + pchol_hs --> Rtotal2 + h + lpchol_hs
is: ENSBTAG00000015230.4
product: 572972
is: ENSBTAG00000012217.4

572948
type: SpeciesReference
stoichiometry: 1.0
species: 462887

462887
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: lysophosphatidylcholine (homo sapiens)_C8H19NO5PFULLRCO2

572936
type: SpeciesReference
stoichiometry: 1.0
species: 458697

572924
type: SpeciesReference
stoichiometry: 1.0
species: 466250

466250
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

572960
type: SpeciesReference
stoichiometry: 1.0
species: 458806

572972
type: SpeciesReference
stoichiometry: 1.0
species: 447069

470397
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Testosterone_C19H28O2

450926
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Choline_C5H14NO

987325
type: Reaction
fast: false
is: ENSBTAG00000038411.1
is: ENSBTAG00000040536.1
is: ENSBTAG00000005540.3
name: cytochrome P450 2A6
is: ENSBTAG00000005559.4
reversible: false
notes: R_P4502A6 subsystem: CYP Metabolism R_P4502A6 equation: [c] : coumarin + h + nadph + o2 --> h2o + hcoumarin + nadp
reactant: 472677
product: 472725
product: 472738
is: ENSBTAG00000004109.3
product: 472750
reactant: 472689
is: ENSBTAG00000025109.3
reactant: 472713
reactant: 472701

472677
type: SpeciesReference
stoichiometry: 1.0
species: 451768

451768
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: coumarin_C9H6O2

472725
type: SpeciesReference
stoichiometry: 1.0
species: 458685

472738
type: SpeciesReference
stoichiometry: 1.0
species: 458989

458989
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: hydroxy coumarin_C9H6O3

472750
type: SpeciesReference
stoichiometry: 1.0
species: 464639

472689
type: SpeciesReference
stoichiometry: 1.0
species: 465234

472713
type: SpeciesReference
stoichiometry: 1.0
species: 464711

472701
type: SpeciesReference
stoichiometry: 1.0
species: 458794

991380
type: Reaction
product: 509475
product: 509487
is: ENSBTAG00000015596.4
reactant: 509450
reactant: 509426
reversible: true
reactant: 509438
notes: R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_DHEASt subsystem: Transport, Extracellular R_DHEASt equation: dheas[e] + hco3[c] <==> dheas[c] + hco3[e]
product: 509462
fast: false

509475
type: SpeciesReference
stoichiometry: 1.0
species: 453832

509487
type: SpeciesReference
stoichiometry: 2.0
species: 458964

509450
type: SpeciesReference
stoichiometry: 1.0
species: 455388

455388
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Estrone 3-sulfate_C18H21O5S

509426
type: SpeciesReference
stoichiometry: 1.0
species: 453844

453844
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Dehydroepiandrosterone sulfate_C19H27O5S

509438
type: SpeciesReference
stoichiometry: 2.0
species: 458952

509462
type: SpeciesReference
stoichiometry: 1.0
species: 455376

455376
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Estrone 3-sulfate_C18H21O5S

447009
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: R group 1 Coenzyme A homo sapiens_XCO2C21H31N7O15P3S

994364
type: Reaction
reactant: 537910
reactant: 537934
fast: false
reactant: 537946
product: 537970
reactant: 537922
is: ENSBTAG00000030257.2
reversible: false
product: 537994
product: 537982
notes: R_PDXPP subsystem: Vitamin B6 Metabolism R_PDXPP equation: [c] : h2o + pdx5p --> pi + pydxn R_PYDXPP subsystem: Vitamin B6 Metabolism R_PYDXPP equation: [c] : h2o + pydx5p --> pi + pydx R_HYPOE subsystem: Vitamin B6 Metabolism R_HYPOE equation: [c] : h2o + pyam5p --> pi + pydam
product: 537958

537910
type: SpeciesReference
stoichiometry: 1.0
species: 466371

466371
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Pyridoxine 5'-phosphate_C8H10NO6P

537934
type: SpeciesReference
stoichiometry: 3.0
species: 458685

537946
type: SpeciesReference
stoichiometry: 1.0
species: 467849

537970
type: SpeciesReference
stoichiometry: 1.0
species: 467861

467861
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Pyridoxal_C8H9NO3

537922
type: SpeciesReference
stoichiometry: 1.0
species: 467825

467825
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Pyridoxamine 5'-phosphate_C8H12N2O5P

537994
type: SpeciesReference
stoichiometry: 1.0
species: 467837

467837
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Pyridoxamine_C8H13N2O2

537982
type: SpeciesReference
stoichiometry: 3.0
species: 466736

537958
type: SpeciesReference
stoichiometry: 1.0
species: 467873

467873
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Pyridoxine_C8H11NO3

467243
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: pregnenolone sulfate_C21H31O5S

452527
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), free chain_C45H64N2O55S6

997705
type: Reaction
notes: R_2OXOADOXm subsystem: Lysine Metabolism R_2OXOADOXm equation: [m] : 2oxoadp + coa + nad --> co2 + glutcoa + nadh R_AKGDm subsystem: Citric Acid Cycle R_AKGDm equation: [m] : akg + coa + nad --> co2 + nadh + succoa
product: 571768
is: ENSBTAG00000006463.4
product: 571756
reactant: 571708
reversible: false
reactant: 571732
is: http://identifiers.org/ec-code/1.2.4.2
fast: false
product: 571780
reactant: 571696
is: ENSBTAG00000006029.3
reactant: 571720
product: 571744

571768
type: SpeciesReference
stoichiometry: 1.0
species: 457658

571756
type: SpeciesReference
stoichiometry: 2.0
species: 451545

571708
type: SpeciesReference
stoichiometry: 2.0
species: 451632

571732
type: SpeciesReference
stoichiometry: 2.0
species: 464542

571780
type: SpeciesReference
stoichiometry: 2.0
species: 464602

571696
type: SpeciesReference
stoichiometry: 1.0
species: 444587

571720
type: SpeciesReference
stoichiometry: 1.0
species: 448970

571744
type: SpeciesReference
stoichiometry: 1.0
species: 469226

452867
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Cytidine_C9H13N3O5

990900
type: Reaction
product: 503995
fast: false
product: 504056
reactant: 503911
reactant: 503947
reactant: 503923
reactant: 503959
product: 504031
reactant: 503935
product: 503983
is: ENSBTAG00000003068.2
product: 504007
product: 504019
reversible: false
reactant: 503971
product: 504044
notes: R_C4STMO1r subsystem: Cholesterol Metabolism R_C4STMO1r equation: [r] : 44mzym + (3) h + (3) nadph + (3) o2 --> 4mzym_int1 + (4) h2o + (3) nadp R_C4STMO2r subsystem: Cholesterol Metabolism R_C4STMO2r equation: [r] : 4mzym_int2 + nad + o2 --> co2 + h + nadh + zym_int2

503995
type: SpeciesReference
stoichiometry: 1.0
species: 471866

504056
type: SpeciesReference
stoichiometry: 1.0
species: 445794

503911
type: SpeciesReference
stoichiometry: 1.0
species: 445468

503947
type: SpeciesReference
stoichiometry: 1.0
species: 445806

503923
type: SpeciesReference
stoichiometry: 4.0
species: 465282

503959
type: SpeciesReference
stoichiometry: 1.0
species: 464566

504031
type: SpeciesReference
stoichiometry: 3.0
species: 464687

503935
type: SpeciesReference
stoichiometry: 3.0
species: 464747

503983
type: SpeciesReference
stoichiometry: 1.0
species: 451557

504007
type: SpeciesReference
stoichiometry: 1.0
species: 464615

504019
type: SpeciesReference
stoichiometry: 4.0
species: 458758

503971
type: SpeciesReference
stoichiometry: 3.0
species: 458867

504044
type: SpeciesReference
stoichiometry: 1.0
species: 458867

994263
type: Reaction
is: ENSBTAG00000002910.4
notes: R_3HBCDm subsystem: Butanoate Metabolism R_3HBCDm equation: [m] : b2coa + h2o <==> 3hbcoa-R
reversible: true
reactant: 537023
product: 537036
reactant: 537011
name: _3-hydroxybutyryl-CoA dehydratase, mitochondrial
fast: false
is: http://identifiers.org/ec-code/4.2.1.55

537023
type: SpeciesReference
stoichiometry: 1.0
species: 450055

537036
type: SpeciesReference
stoichiometry: 1.0
species: 444926

444926
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670

537011
type: SpeciesReference
stoichiometry: 1.0
species: 458733

467377
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: D-Proline_C5H9NO2

996481
type: Reaction
name: _13-cis-retinoic acid isomerase
is: ENSBTAG00000037673.1
reversible: true
product: 558856
reactant: 558844
is: ENSBTAG00000017765.4
is: ENSBTAG00000016472.4
is: ENSBTAG00000031788.2
notes: R_RAI3 subsystem: Vitamin A Metabolism R_RAI3 equation: [c] : retn <==> 13-cis-retn
fast: false
is: ENSBTAG00000012692.4

558856
type: SpeciesReference
stoichiometry: 1.0
species: 444009

444009
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _13-cis-retinoate_C20H27O2

558844
type: SpeciesReference
stoichiometry: 1.0
species: 468164

468164
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Retinoate_C20H27O2

995748
type: Reaction
product: 551792
is: ENSBTAG00000030632.1
reactant: 551720
product: 551780
product: 551804
reactant: 551732
reversible: false
reactant: 551708
product: 551768
product: 551756
fast: false
reactant: 551744
notes: R_DOLPGT3_Ler subsystem: N-Glycan Biosynthesis R_DOLPGT3_Ler equation: [r] : (0.1) dolglcp_L + (0.1) g2m8mpdol_L --> (0.1) dolp_L + (0.1) g3m8mpdol_L + h R_DOLPGT3_Uer subsystem: N-Glycan Biosynthesis R_DOLPGT3_Uer equation: [r] : (0.1) dolglcp_U + (0.1) g2m8mpdol_U --> (0.1) dolp_U + (0.1) g3m8mpdol_U + h

551792
type: SpeciesReference
stoichiometry: 1.0
species: 456514

456514
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: (alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1960H3228N20O770P20

551720
type: SpeciesReference
stoichiometry: 1.0
species: 454391

551780
type: SpeciesReference
stoichiometry: 1.0
species: 454511

551804
type: SpeciesReference
stoichiometry: 2.0
species: 458867

551732
type: SpeciesReference
stoichiometry: 1.0
species: 454415

551708
type: SpeciesReference
stoichiometry: 1.0
species: 456488

551768
type: SpeciesReference
stoichiometry: 1.0
species: 456527

456527
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: (alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1905H3140N20O770P20

551756
type: SpeciesReference
stoichiometry: 1.0
species: 454487

551744
type: SpeciesReference
stoichiometry: 1.0
species: 456475

455630
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

468042
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: alpha-D-Ribose 5-phosphate_C5H9O8P

465548
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Octadecynoyl-ACP (n-C18:2ACP)_C29H51N2O8PRS

990600
type: Reaction
notes: R_PI345P5P subsystem: Inositol Phosphate Metabolism R_PI345P5P equation: [c] : h2o + pail345p_hs --> pail34p_hs + pi R_PI45P5P subsystem: Inositol Phosphate Metabolism R_PI45P5P equation: [c] : h2o + pail45p_hs --> pail4p_hs + pi
is: ENSBTAG00000000817.4
fast: false
product: 501420
reactant: 501360
reversible: false
is: http://identifiers.org/ec-code/3.1.3.36
product: 501408
reactant: 501372
reactant: 501384
product: 501396

501420
type: SpeciesReference
stoichiometry: 1.0
species: 465973

501360
type: SpeciesReference
stoichiometry: 1.0
species: 465949

501408
type: SpeciesReference
stoichiometry: 1.0
species: 466070

501372
type: SpeciesReference
stoichiometry: 1.0
species: 466046

501384
type: SpeciesReference
stoichiometry: 2.0
species: 458685

501396
type: SpeciesReference
stoichiometry: 2.0
species: 466736

445974
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: _5-Amino-2-oxopentanoate_C5H9NO3

996992
type: Reaction
reactant: 563146
product: 563508
reactant: 563183
product: 563291
reactant: 563231
is: http://identifiers.org/ec-code/2.4.1.38
product: 563279
reactant: 562978
reactant: 563086
product: 563255
reversible: false
product: 563267
reactant: 563158
reactant: 563219
product: 563243
product: 563484
reactant: 563134
product: 563411
reactant: 563207
reactant: 563170
is: ENSBTAG00000012626.4
product: 563460
reactant: 563038
product: 563448
reactant: 563122
reactant: 563074
product: 563496
reactant: 563014
product: 563424
product: 563387
reactant: 563050
product: 563436
product: 563472
product: 563399
fast: false
reactant: 563195
product: 563327
product: 563363
is: ENSBTAG00000021897.4
product: 563375
product: 563303
reactant: 563098
product: 563351
notes: R_G14Tg subsystem: N-Glycan Biosynthesis R_G14Tg equation: [g] : fn2m2masn + (2) udpgal --> (2) h + l2fn2m2masn + (2) udp R_G14T7g subsystem: Keratan sulfate biosynthesis R_G14T7g equation: [g] : ksi_pre5 + udpgal --> h + ksi_pre6 + udp R_G14T21g subsystem: Keratan sulfate biosynthesis R_G14T21g equation: [g] : ksii_core4_pre9 + udpgal --> h + ksii_core4_pre10 + udp R_G14T13g subsystem: Keratan sulfate biosynthesis R_G14T13g equation: [g] : ksi_pre23 + udpgal --> h + ksi_pre24 + udp R_G14T17g subsystem: Keratan sulfate biosynthesis R_G14T17g equation: [g] : ksi_pre35 + udpgal --> h + ksi_pre36 + udp R_G14T20g subsystem: Keratan sulfate biosynthesis R_G14T20g equation: [g] : ksii_core4_pre6 + udpgal --> h + ksii_core4_pre7 + udp R_G14T16g subsystem: Keratan sulfate biosynthesis R_G14T16g equation: [g] : ksi_pre32 + udpgal --> h + ksi_pre33 + udp R_G14T3g subsystem: Keratan sulfate biosynthesis R_G14T3g equation: [g] : ksii_core2_pre3 + udpgal --> h + ksii_core2_pre4 + udp R_G14T10g subsystem: Keratan sulfate biosynthesis R_G14T10g equation: [g] : ksi_pre14 + udpgal --> h + ksi_pre15 + udp R_G14T12g subsystem: Keratan sulfate biosynthesis R_G14T12g equation: [g] : ksi_pre20 + udpgal --> h + ksi_pre21 + udp R_G14T15g subsystem: Keratan sulfate biosynthesis R_G14T15g equation: [g] : ksi_pre29 + udpgal --> h + ksi_pre30 + udp R_G14T9g subsystem: Keratan sulfate biosynthesis R_G14T9g equation: [g] : ksi_pre11 + udpgal --> h + ksi_pre12 + udp R_G14T2g subsystem: Keratan sulfate biosynthesis R_G14T2g equation: [g] : ksii_core2_pre1 + udpgal --> h + ksii_core2_pre2 + udp R_G14T6g subsystem: Keratan sulfate biosynthesis R_G14T6g equation: [g] : ksi_pre2 + udpgal --> h + ksi_pre3 + udp R_G14T19g subsystem: Keratan sulfate biosynthesis R_G14T19g equation: [g] : ksii_core4_pre3 + udpgal --> h + ksii_core4_pre4 + udp R_G14T4g subsystem: Keratan sulfate biosynthesis R_G14T4g equation: [g] : ksii_core2_pre6 + udpgal --> h + ksii_core2_pre7 + udp R_G14T8g subsystem: Keratan sulfate …
product: 563339
reactant: 563026
reactant: 563110
reactant: 562990
reactant: 563062
product: 563315
reactant: 563002

563146
type: SpeciesReference
stoichiometry: 1.0
species: 461787

563508
type: SpeciesReference
stoichiometry: 1.0
species: 461347

563183
type: SpeciesReference
stoichiometry: 1.0
species: 461371

461371
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 23_C185H296N13O153S7X

563291
type: SpeciesReference
stoichiometry: 1.0
species: 462054

563231
type: SpeciesReference
stoichiometry: 1.0
species: 462042

563279
type: SpeciesReference
stoichiometry: 1.0
species: 461552

562978
type: SpeciesReference
stoichiometry: 1.0
species: 462006

563086
type: SpeciesReference
stoichiometry: 1.0
species: 461847

461847
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 6_C61H98N5O46SX

563255
type: SpeciesReference
stoichiometry: 1.0
species: 461968

563267
type: SpeciesReference
stoichiometry: 1.0
species: 461419

563158
type: SpeciesReference
stoichiometry: 1.0
species: 461335

461335
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 20_C171H274N12O140S6X

563219
type: SpeciesReference
stoichiometry: 1.0
species: 461883

461883
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 9_C75H120N6O59S2X

563243
type: SpeciesReference
stoichiometry: 1.0
species: 461467

563484
type: SpeciesReference
stoichiometry: 1.0
species: 461775

563134
type: SpeciesReference
stoichiometry: 1.0
species: 461811

563411
type: SpeciesReference
stoichiometry: 1.0
species: 461859

563207
type: SpeciesReference
stoichiometry: 23.0
species: 470848

563170
type: SpeciesReference
stoichiometry: 1.0
species: 461528

563460
type: SpeciesReference
stoichiometry: 1.0
species: 462018

563038
type: SpeciesReference
stoichiometry: 1.0
species: 461250

461250
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 14_C143H230N10O114S4X

563448
type: SpeciesReference
stoichiometry: 1.0
species: 461799

563122
type: SpeciesReference
stoichiometry: 1.0
species: 461491

461491
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 32_C227H362N16O192S10X

563074
type: SpeciesReference
stoichiometry: 1.0
species: 461443

461443
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 29_C213H340N15O179S9X

563496
type: SpeciesReference
stoichiometry: 1.0
species: 461588

563014
type: SpeciesReference
stoichiometry: 1.0
species: 461576

461576
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 5_C101H164N7O75SX

563424
type: SpeciesReference
stoichiometry: 1.0
species: 461262

563387
type: SpeciesReference
stoichiometry: 1.0
species: 461298

563050
type: SpeciesReference
stoichiometry: 1.0
species: 461213

563436
type: SpeciesReference
stoichiometry: 1.0
species: 461540

563472
type: SpeciesReference
stoichiometry: 1.0
species: 461823

563399
type: SpeciesReference
stoichiometry: 1.0
species: 461625

563195
type: SpeciesReference
stoichiometry: 1.0
species: 461613

563327
type: SpeciesReference
stoichiometry: 1.0
species: 461982

563363
type: SpeciesReference
stoichiometry: 23.0
species: 458819

563375
type: SpeciesReference
stoichiometry: 1.0
species: 461503

563303
type: SpeciesReference
stoichiometry: 1.0
species: 461383

563098
type: SpeciesReference
stoichiometry: 1.0
species: 461407

461407
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 26_C199H318N14O166S8X

563351
type: SpeciesReference
stoichiometry: 1.0
species: 462090

563339
type: SpeciesReference
stoichiometry: 23.0
species: 470688

563026
type: SpeciesReference
stoichiometry: 1.0
species: 461286

461286
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate I biosynthesis, precursor 17_C157H252N11O127S5X

563110
type: SpeciesReference
stoichiometry: 1.0
species: 461455

562990
type: SpeciesReference
stoichiometry: 1.0
species: 451720

451720
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: Core 4_C24H40N3O15X

563062
type: SpeciesReference
stoichiometry: 1.0
species: 455799

563315
type: SpeciesReference
stoichiometry: 1.0
species: 461225

563002
type: SpeciesReference
stoichiometry: 1.0
species: 462078

462078
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: keratan sulfate II biosynthesis, precursor 9_C83H133N7O64S2X

461117
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 6_C210H336N15O184S11

468176
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Retinoate_C20H27O2

470143
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N6,N6,N6-Trimethyl-L-lysine_C9H20N2O2

471420
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Xanthine_C5H4N4O2

454944
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-erythro-4-Hydroxyglutamate_C5H8NO5

991416
type: Reaction
fast: false
name: Electron transfer flavoprotein-ubiquinone oxidoreductase
product: 509692
reversible: false
notes: R_ETFQO subsystem: Fatty acid oxidation R_ETFQO equation: [m] : etfrd + q10 --> etfox + q10h2
product: 509704
reactant: 509668
is: http://identifiers.org/ec-code/1.5.5.1
reactant: 509680
is: ENSBTAG00000016679.4

509692
type: SpeciesReference
stoichiometry: 1.0
species: 455412

509704
type: SpeciesReference
stoichiometry: 1.0
species: 467994

467994
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Ubiquinol-10_C59H92O4

509668
type: SpeciesReference
stoichiometry: 1.0
species: 455424

509680
type: SpeciesReference
stoichiometry: 1.0
species: 467970

456366
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: Fumarate_C4H2O4

987901
type: Reaction
product: 477663
reactant: 477591
reactant: 477615
product: 477627
is: ENSBTAG00000009181.4
reactant: 477603
fast: false
notes: R_PI345P5P subsystem: Inositol Phosphate Metabolism R_PI345P5P equation: [c] : h2o + pail345p_hs --> pail34p_hs + pi R_MI145PP subsystem: Inositol Phosphate Metabolism R_MI145PP equation: [c] : h2o + mi145p --> mi14p + pi R_MI1345PP subsystem: Inositol Phosphate Metabolism R_MI1345PP equation: [c] : h2o + mi1345p --> mi134p + pi
product: 477639
is: ENSBTAG00000020173.4
reactant: 477579
is: ENSBTAG00000026067.2
is: ENSBTAG00000019167.4
is: ENSBTAG00000017023.3
reversible: false
product: 477651
is: http://identifiers.org/ec-code/3.1.3.56

477663
type: SpeciesReference
stoichiometry: 1.0
species: 464035

477591
type: SpeciesReference
stoichiometry: 1.0
species: 464011

477615
type: SpeciesReference
stoichiometry: 1.0
species: 463951

477627
type: SpeciesReference
stoichiometry: 1.0
species: 465973

477603
type: SpeciesReference
stoichiometry: 3.0
species: 458685

477639
type: SpeciesReference
stoichiometry: 1.0
species: 463987

477579
type: SpeciesReference
stoichiometry: 1.0
species: 465949

477651
type: SpeciesReference
stoichiometry: 3.0
species: 466736

450226
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Bilirubin_C33H34N4O6

993554
type: Reaction
notes: R_CITL subsystem: Citric Acid Cycle R_CITL equation: [c] : cit --> ac + oaa
reactant: 529372
is: ENSBTAG00000004165.4
name: Citrate lyase
product: 529384
is: http://identifiers.org/ec-code/4.1.3.6
product: 529396
reversible: false
fast: false

529372
type: SpeciesReference
stoichiometry: 1.0
species: 451217

529384
type: SpeciesReference
stoichiometry: 1.0
species: 465367

529396
type: SpeciesReference
stoichiometry: 1.0
species: 447521

996591
type: Reaction
reactant: 560314
product: 560362
product: 560338
fast: false
notes: R_GLCNACT1g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT1g equation: [g] : cs,hs_linkage + uacgam --> h + hs_pre1 + udp
reversible: false
reactant: 560326
is: ENSBTAG00000019026.3
name: alpha-N-acetylglucosaminyltransferase I, Golgi apparatus
product: 560350

560314
type: SpeciesReference
stoichiometry: 1.0
species: 470652

560362
type: SpeciesReference
stoichiometry: 1.0
species: 458819

560338
type: SpeciesReference
stoichiometry: 1.0
species: 459914

459914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: heparan sulfate, precursor 1_C31H49NO25X

560326
type: SpeciesReference
stoichiometry: 1.0
species: 452009

560350
type: SpeciesReference
stoichiometry: 1.0
species: 470688

992113
type: Reaction
reactant: 517297
is: ENSBTAG00000010151.4
fast: false
is: http://identifiers.org/ec-code/4.2.1.1
reactant: 517310
name: carboxylic acid dissociation
is: ENSBTAG00000020418.3
reversible: true
product: 517322
is: ENSBTAG00000016530.3
notes: R_H2CO3Dm subsystem: Miscellaneous R_H2CO3Dm equation: [m] : co2 + h2o <==> h2co3

517297
type: SpeciesReference
stoichiometry: 1.0
species: 458733

517310
type: SpeciesReference
stoichiometry: 1.0
species: 451545

517322
type: SpeciesReference
stoichiometry: 1.0
species: 458601

458601
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: carbonic acid_H2CO3

995772
type: Reaction
product: 552010
is: ENSBTAG00000033166.2
is: ENSBTAG00000001442.4
product: 551998
notes: R_CGLYt3_LPAREN_2_RPAREN_ subsystem: Transport, Extracellular R_CGLYt3_LPAREN_2_RPAREN_ equation: cgly[e] + (2) h[e] --> cgly[c] + (2) h[c]
reversible: false
fast: false
reactant: 551986
reactant: 551974
name: Cys-Gly transport in via proton symport

552010
type: SpeciesReference
stoichiometry: 2.0
species: 458794

551998
type: SpeciesReference
stoichiometry: 1.0
species: 450817

450817
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Cys-Gly_C5H10N2O3S

551986
type: SpeciesReference
stoichiometry: 1.0
species: 450829

450829
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: Cys-Gly_C5H10N2O3S

551974
type: SpeciesReference
stoichiometry: 2.0
species: 458806

448100
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Acetylcholine_C7H16NO2

463165
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: (alpha-D-Mannosyl)5-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1545H2540N20O470P20

988142
type: Reaction
notes: R_GTHPm subsystem: Glutathione Metabolism R_GTHPm equation: [m] : (2) gthrd + h2o2 <==> gthox + (2) h2o
is: http://identifiers.org/ec-code/1.11.1.9
reactant: 479624
product: 479648
reactant: 479612
name: glutathione peroxidase, mitochondria
reversible: true
fast: false
is: ENSBTAG00000008731.2
product: 479636

479624
type: SpeciesReference
stoichiometry: 2.0
species: 458480

479648
type: SpeciesReference
stoichiometry: 1.0
species: 458444

479612
type: SpeciesReference
stoichiometry: 1.0
species: 458649

479636
type: SpeciesReference
stoichiometry: 2.0
species: 458733

466519
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Perillyl alcohol_C10H16O

996133
type: Reaction
notes: R_S23T4g subsystem: Keratan sulfate biosynthesis R_S23T4g equation: [g] : cmpacna + ksii_core4_pre1 --> cmp + h + ksii_core4_pre2 R_S23T2g subsystem: Keratan sulfate biosynthesis R_S23T2g equation: [g] : cmpacna + core2 --> cmp + h + ksii_core2_pre1
fast: false
product: 556095
is: ENSBTAG00000016506.4
reversible: false
product: 556107
reactant: 556071
reactant: 556059
reactant: 556047
is: http://identifiers.org/ec-code/2.4.99.4
product: 556119
product: 556083

556095
type: SpeciesReference
stoichiometry: 1.0
species: 461787

556107
type: SpeciesReference
stoichiometry: 1.0
species: 461994

556071
type: SpeciesReference
stoichiometry: 1.0
species: 451696

556059
type: SpeciesReference
stoichiometry: 1.0
species: 461982

556047
type: SpeciesReference
stoichiometry: 2.0
species: 451471

556119
type: SpeciesReference
stoichiometry: 2.0
species: 451422

556083
type: SpeciesReference
stoichiometry: 2.0
species: 458819

444021
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _13-cis-retinoate_C20H27O2

989663
type: Reaction
reactant: 494145
notes: R_GLUNm subsystem: Glutamate metabolism R_GLUNm equation: [m] : gln-L + h2o --> glu-L + nh4
product: 494169
reactant: 494157
product: 494181
name: glutaminase (mitochondrial)
fast: false
reversible: false
is: ENSBTAG00000009284.4
is: http://identifiers.org/ec-code/3.5.1.2
is: ENSBTAG00000007863.4

494145
type: SpeciesReference
stoichiometry: 1.0
species: 457488

457488
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Glutamine_C5H10N2O3

494169
type: SpeciesReference
stoichiometry: 1.0
species: 464858

494157
type: SpeciesReference
stoichiometry: 1.0
species: 458733

494181
type: SpeciesReference
stoichiometry: 1.0
species: 457562

991164
type: Reaction
reactant: 507018
notes: R_NBAHH_ir subsystem: beta-Alanine metabolism R_NBAHH_ir equation: [c] : carn + h2o --> ala-B + his-L
product: 507054
reactant: 507030
is: ENSBTAG00000021428.4
fast: false
is: http://identifiers.org/ec-code/3.4.13.3
reversible: false
product: 507042
name: Nalpha-(beta-alanyl)-L-histidine hydrolase IR

507018
type: SpeciesReference
stoichiometry: 1.0
species: 458685

507054
type: SpeciesReference
stoichiometry: 1.0
species: 449006

507030
type: SpeciesReference
stoichiometry: 1.0
species: 450611

450611
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Carnosine_C9H14N4O3

507042
type: SpeciesReference
stoichiometry: 1.0
species: 459289

464675
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

457670
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Glyoxylate_C2H1O3

998084
type: Reaction
notes: R_NACASPAH subsystem: Alanine and Aspartate Metabolism R_NACASPAH equation: [c] : Nacasp + h2o --> ac + asp-L
is: http://identifiers.org/ec-code/3.5.1.15
product: 574701
reactant: 574677
fast: false
reactant: 574665
product: 574689
name: N-Acetyl-L-aspartate amidohydrolase
reversible: false
is: ENSBTAG00000038470.1
is: ENSBTAG00000007395.4

574701
type: SpeciesReference
stoichiometry: 1.0
species: 449947

574677
type: SpeciesReference
stoichiometry: 1.0
species: 446937

446937
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Acetyl-L-aspartate_C6H7NO5

574665
type: SpeciesReference
stoichiometry: 1.0
species: 458685

574689
type: SpeciesReference
stoichiometry: 1.0
species: 447521

460763
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: keratan sulfate I, degradation product 19_C146H236N10O124S6

995448
type: Reaction
product: 549234
product: 549270
reactant: 549210
product: 549258
notes: R_S4TASE2ly subsystem: Chondroitin sulfate degradation R_S4TASE2ly equation: [l] : cs_a_deg3 + h2o <==> cs_a_deg4 + h + so4 R_S4TASE3ly subsystem: Chondroitin sulfate degradation R_S4TASE3ly equation: [l] : cs_b + h2o <==> cs_b_deg1 + h + so4 R_S4TASE1ly subsystem: Chondroitin sulfate degradation R_S4TASE1ly equation: [l] : cs_a + h2o <==> cs_a_deg1 + h + so4 R_S4TASE5ly subsystem: Chondroitin sulfate degradation R_S4TASE5ly equation: [l] : cs_e_deg4 + h2o <==> cs_e_deg5 + h + so4 R_S4TASE4ly subsystem: Chondroitin sulfate degradation R_S4TASE4ly equation: [l] : cs_e + h2o <==> cs_e_deg1 + h + so4
product: 549294
reactant: 549150
reactant: 549174
product: 549222
reactant: 549186
reactant: 549162
is: http://identifiers.org/ec-code/3.1.6.12
reactant: 549198
fast: false
reversible: true
product: 549246
is: ENSBTAG00000008341.4
product: 549282

549234
type: SpeciesReference
stoichiometry: 1.0
species: 452130

452130
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), degradation product 1_C45H67N2O46S3

549270
type: SpeciesReference
stoichiometry: 1.0
species: 452491

452491
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 5_C31H47NO35S3

549210
type: SpeciesReference
stoichiometry: 1.0
species: 452527

549258
type: SpeciesReference
stoichiometry: 5.0
species: 458831

549294
type: SpeciesReference
stoichiometry: 1.0
species: 452058

452058
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 1_C45H68N2O43S2

549150
type: SpeciesReference
stoichiometry: 1.0
species: 452118

452118
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate A (GalNAc4S-GlcA), free chain_C45H67N2O46S3

549174
type: SpeciesReference
stoichiometry: 1.0
species: 452166

549222
type: SpeciesReference
stoichiometry: 1.0
species: 452094

452094
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 4_C31H49NO29S

549186
type: SpeciesReference
stoichiometry: 5.0
species: 458721

549162
type: SpeciesReference
stoichiometry: 1.0
species: 452479

549198
type: SpeciesReference
stoichiometry: 1.0
species: 452082

549246
type: SpeciesReference
stoichiometry: 5.0
species: 468767

549282
type: SpeciesReference
stoichiometry: 1.0
species: 452443

452443
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 1_C45H65N2O52S5

992797
type: Reaction
reversible: false
product: 523493
name: L-asparaginase (mitochondrial)
reactant: 523469
product: 523481
notes: R_ASNNm subsystem: Alanine and Aspartate Metabolism R_ASNNm equation: [m] : asn-L + h2o --> asp-L + nh4
is: http://identifiers.org/ec-code/3.5.1.1
fast: false
is: ENSBTAG00000006910.4
reactant: 523457

523493
type: SpeciesReference
stoichiometry: 1.0
species: 449971

449971
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Aspartate_C4H6NO4

523469
type: SpeciesReference
stoichiometry: 1.0
species: 449899

523481
type: SpeciesReference
stoichiometry: 1.0
species: 464858

523457
type: SpeciesReference
stoichiometry: 1.0
species: 458733

996457
type: Reaction
reversible: true
fast: false
is: ENSBTAG00000003864.4
reactant: 558748
name: sulfate transport via sodium symport
reactant: 558760
product: 558772
notes: R_SO4t4_2 subsystem: Transport, Extracellular R_SO4t4_2 equation: (2) na1[e] + so4[e] <==> (2) na1[c] + so4[c]
product: 558784

558748
type: SpeciesReference
stoichiometry: 2.0
species: 464470

558760
type: SpeciesReference
stoichiometry: 1.0
species: 468755

558772
type: SpeciesReference
stoichiometry: 2.0
species: 464458

558784
type: SpeciesReference
stoichiometry: 1.0
species: 468743

994047
type: Reaction
product: 534554
reactant: 534458
product: 534542
is: ENSBTAG00000021002.3
product: 534494
reactant: 534482
reactant: 534398
reactant: 534386
reactant: 534374
product: 534530
reversible: false
fast: false
product: 534518
product: 534506
reactant: 534362
reactant: 534434
reactant: 534422
notes: R_NTD7l subsystem: Nucleic acid degradation R_NTD7l equation: [l] : amp + h2o --> adn + pi R_NTD9l subsystem: Nucleic acid degradation R_NTD9l equation: [l] : gmp + h2o --> gsn + pi R_NTD4l subsystem: Nucleic acid degradation R_NTD4l equation: [l] : cmp + h2o --> cytd + pi R_NTD3l subsystem: Nucleic acid degradation R_NTD3l equation: [l] : dcmp + h2o --> dcyt + pi R_NTD8l subsystem: Nucleic acid degradation R_NTD8l equation: [l] : dgmp + h2o --> dgsn + pi R_NTD2l subsystem: Nucleic acid degradation R_NTD2l equation: [l] : h2o + ump --> pi + uri R_LAPCOAl subsystem: CoA Catabolism R_LAPCOAl equation: [l] : coa + h2o --> dpcoa + pi R_NTD5l subsystem: Nucleic acid degradation R_NTD5l equation: [l] : dtmp + h2o --> pi + thymd R_3NTD7l subsystem: Nucleic acid degradation R_3NTD7l equation: [l] : 3amp + h2o --> adn + pi R_NTD6l subsystem: Nucleic acid degradation R_NTD6l equation: [l] : damp + h2o --> dad-2 + pi
product: 534590
reactant: 534470
product: 534578
product: 534566
reactant: 534410
reactant: 534446
product: 534602
is: http://identifiers.org/ec-code/3.1.3.5

534554
type: SpeciesReference
stoichiometry: 1.0
species: 452843

534458
type: SpeciesReference
stoichiometry: 1.0
species: 454703

534542
type: SpeciesReference
stoichiometry: 1.0
species: 454583

454583
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Dephospho-CoA_C21H33N7O13P2S

534494
type: SpeciesReference
stoichiometry: 10.0
species: 466772

534482
type: SpeciesReference
stoichiometry: 1.0
species: 453011

453011
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: dAMP_C10H12N5O6P

534398
type: SpeciesReference
stoichiometry: 1.0
species: 453156

534386
type: SpeciesReference
stoichiometry: 1.0
species: 470975

470975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: UMP_C9H11N2O9P

534374
type: SpeciesReference
stoichiometry: 1.0
species: 449332

534530
type: SpeciesReference
stoichiometry: 1.0
species: 471143

534518
type: SpeciesReference
stoichiometry: 1.0
species: 452903

452903
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Deoxyadenosine_C10H13N5O3

534506
type: SpeciesReference
stoichiometry: 1.0
species: 453578

534362
type: SpeciesReference
stoichiometry: 1.0
species: 451434

534434
type: SpeciesReference
stoichiometry: 10.0
species: 458721

534422
type: SpeciesReference
stoichiometry: 1.0
species: 453530

453530
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: dGMP_C10H12N5O7P

534590
type: SpeciesReference
stoichiometry: 2.0
species: 448426

534470
type: SpeciesReference
stoichiometry: 1.0
species: 444829

444829
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: _3'-AMP_C10H12N5O7P

534578
type: SpeciesReference
stoichiometry: 1.0
species: 458311

534566
type: SpeciesReference
stoichiometry: 1.0
species: 453300

453300
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Deoxycytidine_C9H13N3O4

534410
type: SpeciesReference
stoichiometry: 1.0
species: 458106

534446
type: SpeciesReference
stoichiometry: 1.0
species: 451619

451619
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: Coenzyme A_C21H32N7O16P3S

534602
type: SpeciesReference
stoichiometry: 1.0
species: 470095

992833
type: Reaction
reversible: false
is: ENSBTAG00000020371.4
name: peroxisomal acyl-CoA thioesterase
fast: false
product: 523902
notes: R_PTE2x subsystem: Fatty Acid Metabolism R_PTE2x equation: [x] : h2o + pmtcoa --> coa + h + hdca
product: 523890
reactant: 523866
product: 523878
reactant: 523854

523902
type: SpeciesReference
stoichiometry: 1.0
species: 459049

459049
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Hexadecanoate (n-C16:0)_C16H31O2

523890
type: SpeciesReference
stoichiometry: 1.0
species: 458879

523866
type: SpeciesReference
stoichiometry: 1.0
species: 458770

523878
type: SpeciesReference
stoichiometry: 1.0
species: 451671

523854
type: SpeciesReference
stoichiometry: 1.0
species: 466856

990300
type: Reaction
notes: R_THMt3 subsystem: Transport, Extracellular R_THMt3 equation: h[c] + thm[e] <==> h[e] + thm[c]
reversible: true
reactant: 499347
reactant: 499335
product: 499359
fast: false
product: 499371
is: ENSBTAG00000011287.4
name: Thiamine transport in via proton antiport
is: ENSBTAG00000038897.1

499347
type: SpeciesReference
stoichiometry: 1.0
species: 458794

499335
type: SpeciesReference
stoichiometry: 1.0
species: 469939

499359
type: SpeciesReference
stoichiometry: 1.0
species: 458806

499371
type: SpeciesReference
stoichiometry: 1.0
species: 469927

464760
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

451658
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Coenzyme A_C21H32N7O16P3S

464205
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: (S)-Methylmalonyl-CoA_C25H35N7O19P3S

459757
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: heparan sulfate, degradation product 4_C73H104N4O92S10

990876
type: Reaction
product: 503790
reactant: 503778
notes: R_5MTHFt subsystem: Transport, Extracellular R_5MTHFt equation: _5mthf[e] <==> 5mthf[c]
is: ENSBTAG00000021007.2
is: ENSBTAG00000038532.1
fast: false
reversible: true
name: _5-Methyltetrahydrofolate transport via receptor binding and protolysis

503790
type: SpeciesReference
stoichiometry: 1.0
species: 446358

446358
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _5-Methyltetrahydrofolate_C20H24N7O6

503778
type: SpeciesReference
stoichiometry: 1.0
species: 446370

446370
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: _5-Methyltetrahydrofolate_C20H24N7O6

446574
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _6-Pyruvoyl-5,6,7,8-tetrahydropterin_C9H11N5O3

995460
type: Reaction
reversible: false
product: 549343
notes: R_LRAT subsystem: Vitamin A Metabolism R_LRAT equation: [c] : pchol_hs + retinol --> lpchol_hs + retfa
reactant: 549306
name: Lecithin retinol acyltransferase
reactant: 549319
fast: false
product: 549331
is: ENSBTAG00000017167.4

549343
type: SpeciesReference
stoichiometry: 1.0
species: 462875

462875
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: lysophosphatidylcholine (homo sapiens)_C8H19NO5PFULLRCO2

549306
type: SpeciesReference
stoichiometry: 1.0
species: 466238

549319
type: SpeciesReference
stoichiometry: 1.0
species: 468152

468152
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Retinol_C20H30O

549331
type: SpeciesReference
stoichiometry: 1.0
species: 468054

991885
type: Reaction
product: 513228
is: ENSBTAG00000012982.3
product: 513240
notes: R_PPNCL3 subsystem: CoA Biosynthesis R_PPNCL3 equation: [c] : 4ppan + atp + cys-L --> 4ppcys + amp + h + ppi
product: 513264
reactant: 513203
reactant: 513216
is: http://identifiers.org/ec-code/6.3.2.5
product: 513252
reversible: false
fast: false
name: phosphopantothenate-cysteine ligase
reactant: 513191

513228
type: SpeciesReference
stoichiometry: 1.0
species: 445866

513240
type: SpeciesReference
stoichiometry: 1.0
species: 449296

513264
type: SpeciesReference
stoichiometry: 1.0
species: 467000

513203
type: SpeciesReference
stoichiometry: 1.0
species: 449983

513216
type: SpeciesReference
stoichiometry: 1.0
species: 445842

445842
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: D-4'-Phosphopantothenate_C9H15NO8P

513252
type: SpeciesReference
stoichiometry: 1.0
species: 458794

513191
type: SpeciesReference
stoichiometry: 1.0
species: 452759

452154
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443658
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), degradation product 3_C37H55NO38S2

458009
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: GM1alpha (homo sapiens)_C55H95N3O30FULLRCO

456415
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: (alpha-D-Glucosyl)-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C76H127N2O60X

444611
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _2-Phosphoglycolate_C2H2O6P

451265
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: L-Citrulline_C6H13N3O3

994571
type: Reaction
is: ENSBTAG00000009413.3
reactant: 540926
reversible: true
reactant: 540913
name: L-ascorbate transport via proton symport
fast: false
is: ENSBTAG00000032366.2
product: 540938
product: 540950
notes: R_ASCBt4 subsystem: Transport, Extracellular R_ASCBt4 equation: ascb-L[e] + na1[e] <==> ascb-L[c] + na1[c]
is: ENSBTAG00000031548.2
is: ENSBTAG00000010798.4

540926
type: SpeciesReference
stoichiometry: 1.0
species: 449862

540913
type: SpeciesReference
stoichiometry: 1.0
species: 464470

540938
type: SpeciesReference
stoichiometry: 1.0
species: 464458

540950
type: SpeciesReference
stoichiometry: 1.0
species: 449850

994824
type: Reaction
product: 544206
reversible: false
reactant: 544133
is: ENSBTAG00000038878.1
product: 544242
fast: false
is: http://identifiers.org/ec-code/1.1.1.204
product: 544194
is: ENSBTAG00000012519.4
reactant: 544158
product: 544230
product: 544218
notes: R_XAO2x subsystem: Purine Catabolism R_XAO2x equation: [x] : h2o + hxan + o2 --> h2o2 + xan R_XAOx subsystem: Purine Catabolism R_XAOx equation: [x] : h2o + o2 + xan --> h2o2 + urate R_XANDp subsystem: Purine Catabolism R_XANDp equation: [x] : h2o + nad + xan --> h + nadh + urate
reactant: 544170
reactant: 544145
reactant: 544182
is: ENSBTAG00000026812.3

544206
type: SpeciesReference
stoichiometry: 2.0
species: 471059

544133
type: SpeciesReference
stoichiometry: 3.0
species: 458770

544242
type: SpeciesReference
stoichiometry: 1.0
species: 458879

544194
type: SpeciesReference
stoichiometry: 1.0
species: 464627

544158
type: SpeciesReference
stoichiometry: 1.0
species: 460084

460084
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443695
name: Hypoxanthine_C5H4N4O

544230
type: SpeciesReference
stoichiometry: 1.0
species: 471420

544218
type: SpeciesReference
stoichiometry: 2.0
species: 458673

544170
type: SpeciesReference
stoichiometry: 1.0
species: 464578

544145
type: SpeciesReference
stoichiometry: 2.0
species: 465294

544182
type: SpeciesReference
stoichiometry: 2.0
species: 471420

995160
type: Reaction
notes: R_PMANM subsystem: Fructose and Mannose Metabolism R_PMANM equation: [c] : man1p <==> man6p
product: 546954
is: ENSBTAG00000004009.3
reactant: 546942
name: phosphomannomutase
reversible: true
fast: false
is: ENSBTAG00000001440.3
is: http://identifiers.org/ec-code/5.4.2.8

546954
type: SpeciesReference
stoichiometry: 1.0
species: 463587

546942
type: SpeciesReference
stoichiometry: 1.0
species: 463575

447485
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Aminoacetone_C3H8NO

996980
type: Reaction
fast: false
reactant: 562941
product: 562966
notes: R_SIAASE subsystem: N-Glycan Degradation R_SIAASE equation: [c] : (2) h2o + s2l2n2m2mn --> (2) acnam + l2n2m2mn
product: 562953
reversible: false
is: ENSBTAG00000014833.4
is: http://identifiers.org/ec-code/3.2.1.18
is: ENSBTAG00000020672.4
reactant: 562929
name: sialidase

562941
type: SpeciesReference
stoichiometry: 2.0
species: 458685

562966
type: SpeciesReference
stoichiometry: 2.0
species: 448184

562953
type: SpeciesReference
stoichiometry: 1.0
species: 462102

462102
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: de-Fuc, reducing GlcNAc removed, de-Sia form of PA6 (w/o peptide linkage)_C54H91N3O41

562929
type: SpeciesReference
stoichiometry: 1.0
species: 468334

991236
type: Reaction
product: 507418
is: http://identifiers.org/ec-code/3.1.3.67
notes: R_PI345P3Pn subsystem: Inositol Phosphate Metabolism R_PI345P3Pn equation: [n] : h2o + pail345p_hs --> pail45p_hs + pi R_PI345P3P subsystem: Inositol Phosphate Metabolism R_PI345P3P equation: [c] : h2o + pail345p_hs --> pail45p_hs + pi
reactant: 507369
reversible: false
reactant: 507406
fast: false
product: 507455
product: 507443
product: 507430
reactant: 507394
is: ENSBTAG00000009498.4
reactant: 507381

507418
type: SpeciesReference
stoichiometry: 1.0
species: 466058

507369
type: SpeciesReference
stoichiometry: 1.0
species: 465949

507406
type: SpeciesReference
stoichiometry: 1.0
species: 458746

507455
type: SpeciesReference
stoichiometry: 1.0
species: 466796

466796
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: Phosphate_HO4P

507443
type: SpeciesReference
stoichiometry: 1.0
species: 466046

507430
type: SpeciesReference
stoichiometry: 1.0
species: 466736

507394
type: SpeciesReference
stoichiometry: 1.0
species: 458685

507381
type: SpeciesReference
stoichiometry: 1.0
species: 465961

465961
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443682
name: phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)_C9H13O18P4FULLRCO2FULLR2CO2

997328
type: Reaction
fast: false
is: http://identifiers.org/ec-code/2.7.8.11
is: ENSBTAG00000007954.2
reversible: true
product: 566697
reactant: 566673
notes: R_CDIPTr subsystem: Glycerophospholipid Metabolism R_CDIPTr equation: [c] : cdpdag_hs + inost <==> cmp + h + pail_hs
reactant: 566661
product: 566709
product: 566685
name: phosphatidylinositol synthase (Homo sapiens)

566697
type: SpeciesReference
stoichiometry: 1.0
species: 466130

566673
type: SpeciesReference
stoichiometry: 1.0
species: 450781

566661
type: SpeciesReference
stoichiometry: 1.0
species: 460425

566709
type: SpeciesReference
stoichiometry: 1.0
species: 458794

566685
type: SpeciesReference
stoichiometry: 1.0
species: 451398

449055
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: D-Alanine_C3H7NO2

994348
type: Reaction
reactant: 537813
fast: false
product: 537897
is: ENSBTAG00000004625.4
reactant: 537825
reactant: 537837
reversible: false
product: 537873
notes: R_GLPASE2 subsystem: Starch and Sucrose Metabolism R_GLPASE2 equation: [c] : glygn3 + (7) h2o --> Tyr-ggn + (7) glc-D R_GLPASE1 subsystem: Starch and Sucrose Metabolism R_GLPASE1 equation: [c] : glygn2 + (3) pi --> dxtrn + (3) g1p
is: ENSBTAG00000001032.4
is: ENSBTAG00000011494.4
product: 537861
reactant: 537849
is: http://identifiers.org/ec-code/2.4.1.1
product: 537885

537813
type: SpeciesReference
stoichiometry: 1.0
species: 457936

537897
type: SpeciesReference
stoichiometry: 1.0
species: 447425

537825
type: SpeciesReference
stoichiometry: 1.0
species: 457961

457961
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: glycogen, structure 3 (glycogenin-7[1,4-Glc])_C42H71O36X

537837
type: SpeciesReference
stoichiometry: 3.0
species: 466736

537873
type: SpeciesReference
stoichiometry: 1.0
species: 454932

454932
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: phosphorylase-limit dextrin (glycogenin-1,6{4[1,4-Glc], 4[1,4-Glc]})_C48H81O41X

537861
type: SpeciesReference
stoichiometry: 3.0
species: 456451

537849
type: SpeciesReference
stoichiometry: 7.0
species: 458685

537885
type: SpeciesReference
stoichiometry: 7.0
species: 457356

466034
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _1-Phosphatidyl-1D-myo-inositol 3-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

996566
type: Reaction
fast: false
is: ENSBTAG00000015743.4
is: ENSBTAG00000002715.3
product: 559663
product: 559651
is: http://identifiers.org/ec-code/1.7.1.7
notes: R_GMPR subsystem: Nucleotides R_GMPR equation: [c] : gmp + (2) h + nadph --> imp + nadp + nh4
reversible: false
name: GMP reductase
reactant: 559627
product: 559675
reactant: 559615
reactant: 559639

559663
type: SpeciesReference
stoichiometry: 1.0
species: 464639

559651
type: SpeciesReference
stoichiometry: 1.0
species: 464834

559627
type: SpeciesReference
stoichiometry: 2.0
species: 458794

559675
type: SpeciesReference
stoichiometry: 1.0
species: 460376

559615
type: SpeciesReference
stoichiometry: 1.0
species: 458070

559639
type: SpeciesReference
stoichiometry: 1.0
species: 464711

455400
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Estrone 3-sulfate_C18H21O5S

989258
type: Reaction
reactant: 490360
product: 490409
reversible: false
reactant: 490373
name: phospholipase A2
is: http://identifiers.org/ec-code/3.1.1.4
product: 490385
notes: R_PLA2_2 subsystem: Glycerophospholipid Metabolism R_PLA2_2 equation: [c] : h2o + pchol_hs --> Rtotal2 + h + lpchol_hs
fast: false
is: ENSBTAG00000014015.4
product: 490397

490360
type: SpeciesReference
stoichiometry: 1.0
species: 466238

490409
type: SpeciesReference
stoichiometry: 1.0
species: 458794

490373
type: SpeciesReference
stoichiometry: 1.0
species: 458685

490385
type: SpeciesReference
stoichiometry: 1.0
species: 462875

490397
type: SpeciesReference
stoichiometry: 1.0
species: 447057

994800
type: Reaction
is: http://identifiers.org/ec-code/3.4.11.2
product: 544011
fast: false
is: ENSBTAG00000016881.4
reversible: false
notes: R_AMPTASECGe subsystem: Glutathione Metabolism R_AMPTASECGe equation: [e] : cgly + h2o --> cys-L + gly R_AMPTASECG subsystem: Glutathione Metabolism R_AMPTASECG equation: [c] : cgly + h2o --> cys-L + gly
product: 543999
product: 543987
product: 544024
reactant: 543975
reactant: 543963
reactant: 543951
reactant: 543939

544011
type: SpeciesReference
stoichiometry: 1.0
species: 452771

543999
type: SpeciesReference
stoichiometry: 1.0
species: 452759

543987
type: SpeciesReference
stoichiometry: 1.0
species: 457707

544024
type: SpeciesReference
stoichiometry: 1.0
species: 457719

543975
type: SpeciesReference
stoichiometry: 1.0
species: 450829

543963
type: SpeciesReference
stoichiometry: 1.0
species: 458685

543951
type: SpeciesReference
stoichiometry: 1.0
species: 458697

543939
type: SpeciesReference
stoichiometry: 1.0
species: 450817

444273
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _24R,25-Dihydroxyvitamin D3_C27H44O3

455534
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Formyl-5-hydroxykynurenamine_C10H13N2O3

448040
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443646
name: (Gal)1 (Glc)1 (GlcNAc)1 (Cer)1_C38H69N2O17FULLRCO

989447
type: Reaction
notes: R_GLDBRAN subsystem: Starch and Sucrose Metabolism R_GLDBRAN equation: [c] : dxtrn + h2o --> glc-D + glygn3
product: 491995
reactant: 491971
reversible: false
is: ENSBTAG00000006491.4
name: glycogen debranching enzyme
fast: false
is: http://identifiers.org/ec-code/3.2.1.33
reactant: 491983
product: 492007

491995
type: SpeciesReference
stoichiometry: 1.0
species: 457961

491971
type: SpeciesReference
stoichiometry: 1.0
species: 454932

491983
type: SpeciesReference
stoichiometry: 1.0
species: 458685

492007
type: SpeciesReference
stoichiometry: 1.0
species: 457356

ORG:
  orgname: University of Missouri - Columbia
n:
  given: Conant
  family: Conant

446646
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: _7-Dehydrocholesterol_C27H44O

465403
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: _9-O-Acetylated GD3 (homo sapiens)_C54H90N3O29FULLRCO

450443
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443622
name: Benzoate_C7H5O2

446949
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: N-Acetylserotonin_C12H14N2O2

449019
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: beta-Alanine_C3H7NO2

470324
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Triiodothyronine_C15H12I3NO4

471721
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443670
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane_C27H48O3

987949
type: Reaction
reactant: 478091
notes: R_ESTSULT subsystem: Steroid Metabolism R_ESTSULT equation: [c] : estrone + paps --> estrones + h + pap R_DHEASULT subsystem: Steroid Metabolism R_DHEASULT equation: [c] : dhea + paps --> dheas + h + pap
reactant: 478079
product: 478140
product: 478153
reactant: 478103
is: ENSBTAG00000001249.4
product: 478128
product: 478115
is: http://identifiers.org/ec-code/2.8.2.4
fast: false
reversible: false
is: http://identifiers.org/ec-code/2.8.2.2
is: ENSBTAG00000011952.2
is: ENSBTAG00000016032.4

478091
type: SpeciesReference
stoichiometry: 1.0
species: 455316

455316
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: Estrone_C18H22O2

478079
type: SpeciesReference
stoichiometry: 1.0
species: 453808

478140
type: SpeciesReference
stoichiometry: 1.0
species: 453832

478153
type: SpeciesReference
stoichiometry: 2.0
species: 458794

478103
type: SpeciesReference
stoichiometry: 2.0
species: 466214

478128
type: SpeciesReference
stoichiometry: 2.0
species: 466190

478115
type: SpeciesReference
stoichiometry: 1.0
species: 455376

995244
type: Reaction
product: 547631
product: 547619
reactant: 547582
notes: R_THYOXt subsystem: Transport, Extracellular R_THYOXt equation: hco3[c] + thyox-L[e] <==> hco3[e] + thyox-L[c] R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_GCHOLAt subsystem: Transport, Extracellular R_GCHOLAt equation: gchola[e] + hco3[c] <==> gchola[c] + hco3[e] R_PROSTGE2t subsystem: Transport, Extracellular R_PROSTGE2t equation: hco3[c] + prostge2[e] <==> hco3[e] + prostge2[c] R_CHOLATEt subsystem: Transport, Extracellular R_CHOLATEt equation: cholate[e] + hco3[c] <==> cholate[c] + hco3[e] R_TRIODTHYt subsystem: Transport, Extracellular R_TRIODTHYt equation: hco3[c] + triodthy[e] <==> hco3[e] + triodthy[c] R_DHEASt subsystem: Transport, Extracellular R_DHEASt equation: dheas[e] + hco3[c] <==> dheas[c] + hco3[e] R_TCHOLAt subsystem: Transport, Extracellular R_TCHOLAt equation: hco3[c] + tchola[e] <==> hco3[e] + tchola[c] R_ESTRADIOLGLCt subsystem: Transport, Extracellular R_ESTRADIOLGLCt equation: estradiolglc[e] + hco3[c] <==> estradiolglc[c] + hco3[e]
reactant: 547546
fast: false
product: 547679
reactant: 547533
product: 547667
reactant: 547496
product: 547655
reversible: true
reactant: 547594
reactant: 547509
product: 547691
reactant: 547558
product: 547715
reactant: 547521
product: 547703
reactant: 547606
is: ENSBTAG00000003282.3
reactant: 547570
product: 547727
product: 547643

547631
type: SpeciesReference
stoichiometry: 1.0
species: 467546

547619
type: SpeciesReference
stoichiometry: 1.0
species: 455376

547582
type: SpeciesReference
stoichiometry: 1.0
species: 470336

547546
type: SpeciesReference
stoichiometry: 1.0
species: 457067

547679
type: SpeciesReference
stoichiometry: 1.0
species: 470119

470119
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443610
name: L-Thyroxine_C15H11I4NO4

547533
type: SpeciesReference
stoichiometry: 1.0
species: 470131

470131
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: L-Thyroxine_C15H11I4NO4

547667
type: SpeciesReference
stoichiometry: 1.0
species: 469383

547496
type: SpeciesReference
stoichiometry: 1.0
species: 469395

547655
type: SpeciesReference
stoichiometry: 1.0
species: 453832

547594
type: SpeciesReference
stoichiometry: 1.0
species: 455244

455244
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 443634
name: estradiol glucuronide_C24H32O8

547509
type: SpeciesReference
stoichiometry: 1.0
species: 453844

547691
type: SpeciesReference
stoichiometry: 1.0
species: 457055

547558
type: SpeciesReference
stoichiometry: 1.0
species: 467558

547715
type: SpeciesReference
stoichiometry: 1.0
species: 470324