MODEL1008120002
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species: 186344
species: 180752
species: 179134
species: 184639
reaction: 948538
species: 171123
species: 183844
species: 170145
species: 180282
reaction: 947889
species: 181474
species: 185605
species: 182587
reaction: 949403
species: 177772
species: 163088
species: 166495
species: 170628
species: 161405
species: 162484
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species: 161124
species: 170870
species: 166303
species: 178678
species: 165271
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species: 172029
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species: 184194
species: 162943
reaction: 952483
reaction: 950931
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species: 178087
species: 180403
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species: 177664
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species: 188550
species: 180824
species: 176565
species: 172535
species: 187159
reaction: 953601
species: 168751
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species: 173838
species: 186682
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species: 186549
species: 163221
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species: 175237
species: 163896
species: 162556
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species: 188754
species: 166279
species: 178329
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species: 179231
species: 165653
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reaction: 948202
species: 186308
species: 180716
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species: 176457
species: 171220
species: 168316
species: 172306
species: 163655
reaction: 949247
reaction: 947576

173497
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: D-Glucose 6-phosphate_C6H11O9P

160526
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size: NaN
spatial dimensions: 3.0

186344
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: Thiocyanate_CNS

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180752
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Methionine_C5H11NO2S

160538
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constant: true
size: NaN
spatial dimensions: 3.0

179134
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: D-Lactaldehyde_C3H6O2

184639
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initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: pentadecanoate_C15H29O2

160514
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constant: true
size: NaN
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948538
type: Reaction
is: ENSMUSG00000004610.2
reactant: 218253
product: 218277
name: electron transfer flavoprotein
fast: false
reactant: 218240
notes: R_ETF subsystem: Fatty acid oxidation R_ETF equation: [m] : etfox + fadh2 --> etfrd + fad
reversible: false
is: ENSMUSG00000032314.7
product: 218265

218253
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species: 172547

172547
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initial concentration: NaN
initial amount: NaN
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name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

218277
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species: 172499

172499
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initial concentration: NaN
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name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

218240
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species: 172343

172343
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boundary condition: false
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initial concentration: NaN
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218265
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species: 172355

172355
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name: Electron transfer flavoprotein reduced_RH2

171123
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initial concentration: NaN
initial amount: NaN
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name: N,N-Dimethylglycine_C4H9NO2

183844
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initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Propionate (n-C3:0)_C3H5O2

170145
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: docosa-4,7,10,13,16-pentaenoyl coenzyme A_C43H64N7O17P3S

160598
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constant: true
size: NaN
spatial dimensions: 3.0

180282
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: mannosyl-3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol (M4A)_C61H116N4O43P4FULLRCO2FULLR2CO2

947889
type: Reaction
notes: R_MELATNOX subsystem: Tryptophan metabolism R_MELATNOX equation: [c] : h + melatn + nadph + o2 --> 6hoxmelatn + h2o + nadp R_P4502C19 subsystem: CYP Metabolism R_P4502C19 equation: [c] : h + nadph + o2 + omeprazole --> 5homeprazole + h2o + nadp R_P4502C94 subsystem: Limonene and pinene degradation R_P4502C94 equation: [c] : appnn + h + nadph + o2 --> apnnox + h2o + nadp R_P4502C92 subsystem: Limonene and pinene degradation R_P4502C92 equation: [c] : h + limnen + nadph + o2 --> carveol + h2o + nadp R_P4502C93 subsystem: Limonene and pinene degradation R_P4502C93 equation: [c] : h + limnen + nadph + o2 --> h2o + nadp + perillyl
reactant: 212911
fast: false
product: 212959
reversible: false
is: http://identifiers.org/ec-code/1.14.14.1
reactant: 212887
reactant: 212875
product: 213007
product: 212971
reactant: 212899
product: 213019
product: 213031
is: ENSMUSG00000053411.7
reactant: 212935
reactant: 212923
product: 212995
product: 212983
reactant: 212947

212911
type: SpeciesReference
stoichiometry: 1.0
species: 166471

166471
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: (+)-alpha-Pinene_C10H16

212959
type: SpeciesReference
stoichiometry: 1.0
species: 166411

166411
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: alpha-Pinene-oxide_C10H16O

212887
type: SpeciesReference
stoichiometry: 1.0
species: 180584

180584
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Melatonin_C13H16N2O2

212875
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species: 182623

182623
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: omeprazole_C17H19N3O3S

213007
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species: 163124

163124
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: _5 hydroxy omeprazole_C17H19N3O4S

212971
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species: 167555

167555
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: (E)-carveol_C10H16O

212899
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species: 179485

179485
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Limonene_C10H16

213019
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species: 175614

175614
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: H2O_H2O

213031
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species: 183434

183434
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: Perillyl alcohol_C10H16O

212935
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species: 175722

175722
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: H+_H

212923
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species: 182154

182154
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: O2_O2

212995
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species: 181558

181558
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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212983
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species: 163426

163426
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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212947
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species: 181631

181631
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boundary condition: false
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initial amount: NaN
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181474
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

160586
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size: NaN
spatial dimensions: 3.0

185605
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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182587
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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949403
type: Reaction
fast: false
product: 226901
reactant: 226864
reversible: true
product: 226925
notes: R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_DHEASt subsystem: Transport, Extracellular R_DHEASt equation: dheas[e] + hco3[c] <==> dheas[c] + hco3[e]
reactant: 226889
product: 226913
is: ENSMUSG00000030737.7
reactant: 226877

226901
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species: 172306

172306
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Estrone 3-sulfate_C18H21O5S

226864
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species: 170773

170773
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Dehydroepiandrosterone sulfate_C19H27O5S

226925
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species: 175890

175890
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Bicarbonate_CHO3

226889
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species: 172318

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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: Estrone 3-sulfate_C18H21O5S

226913
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species: 170761

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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: Dehydroepiandrosterone sulfate_C19H27O5S

226877
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species: 175878

175878
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Bicarbonate_CHO3

177772
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 24_C118H191N8O101S5

160562
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constant: true
size: NaN
spatial dimensions: 3.0

163088
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-Formyltetrahydrofolate_C20H21N7O7

166495
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Acetylputrescine_C6H15N2O

170628
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _3alpha,7alpha-Dihydroxy-5beta-cholestanate_C27H45O4

161405
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _2-Hydroxyphenylacetate_C8H7O3

162484
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _4-Aminobutanoate_C4H9NO2

955957
type: Reaction
product: 291991
product: 291967
reversible: false
product: 291979
name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
reactant: 291955
fast: false
reactant: 291943
is: ENSMUSG00000022686.5
notes: R_B3GNT51g subsystem: Blood Group Biosynthesis R_B3GNT51g equation: [g] : galgluside_hs + uacgam --> acglcgalgluside_hs + h + udp

291991
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stoichiometry: 1.0
species: 175746

175746
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: H+_H

160550
type: Compartment
constant: true
size: NaN
spatial dimensions: 3.0

291967
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stoichiometry: 1.0
species: 164956

164956
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (Gal)1 (Glc)1 (GlcNAc)1 (Cer)1_C38H69N2O17FULLRCO

291979
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stoichiometry: 1.0
species: 187608

187608
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: UDP_C9H11N2O12P2

291955
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stoichiometry: 1.0
species: 173802

173802
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: galactosyl glucosyl ceramide_C30H56NO12FULLRCO

291943
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species: 187572

187572
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550

173389
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C82H137N2O65X

161124
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-1-Pyrroline-3-hydroxy-5-carboxylate_C5H6NO3

170870
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598

166303
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: androstanedione_C19H28O2

178678
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate II (core 2-linked)_C81H129N6O67S3X

165271
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Adenine_C5H5N5

183736
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Phosphate_HO4P

172029
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Eicosatetranoyl carnitine_C27H45NO4

949019
type: Reaction
product: 222990
reactant: 222977
notes: R_MACACI subsystem: Tyrosine metabolism R_MACACI equation: [c] : 4mlacac --> 4fumacac
is: ENSMUSG00000061322.6
is: http://identifiers.org/ec-code/5.2.1.2
fast: false
reversible: false
name: maleylacetoacetate isomerase

222990
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species: 162520

162520
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-Fumarylacetoacetate_C8H6O6

222977
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species: 162652

162652
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-Maleylacetoacetate_C8H6O6

184194
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Progesterone_C21H30O2

162943
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: _5alpha-Dihydrotestosterone glucuronide_C25H38O8

952483
type: Reaction
reactant: 257489
reactant: 257513
notes: R_P45011B11m subsystem: Steroid Metabolism R_P45011B11m equation: [m] : 11docrtstrn + h + nadph + o2 --> crtstrn + h2o + nadp R_P45011B12m subsystem: Steroid Metabolism R_P45011B12m equation: [m] : 11docrtsl + h + nadph + o2 --> crtsl + h2o + nadp
is: ENSMUSG00000022589.5
product: 257573
is: ENSMUSG00000075604.2
product: 257549
reversible: false
fast: false
reactant: 257501
is: http://identifiers.org/ec-code/1.14.15.4
reactant: 257477
product: 257561
reactant: 257525
product: 257537

257489
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species: 160810

160810
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _11-Deoxycortisol_C21H30O4

257513
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species: 182178

182178
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: O2_O2

257573
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species: 181583

181583
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

257549
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stoichiometry: 2.0
species: 175662

175662
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: H2O_H2O

257501
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species: 181643

181643
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

257477
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stoichiometry: 1.0
species: 160835

160835
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _11-Deoxycorticosterone_C21H30O3

257561
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stoichiometry: 1.0
species: 168884

168884
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Corticosterone_C21H30O4

257525
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stoichiometry: 2.0
species: 175770

175770
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: H+_H

257537
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stoichiometry: 1.0
species: 168860

168860
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Cortisol_C21H30O5

950931
type: Reaction
reactant: 242368
is: ENSMUSG00000032527.4
product: 242416
is: http://identifiers.org/ec-code/6.4.1.3
fast: false
product: 242428
reactant: 242332
reactant: 242319
product: 242380
reactant: 242356
product: 242392
product: 242404
is: http://identifiers.org/ec-code/3.1.4.17
reactant: 242344
notes: R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h R_PPCOACm subsystem: Valine, Leucine, and Isoleucine Metabolism R_PPCOACm equation: [m] : atp + hco3 + ppcoa --> adp + h + mmcoa-S + pi
reversible: false
product: 242440

242368
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stoichiometry: 1.0
species: 175614

242416
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stoichiometry: 1.0
species: 165411

165411
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: ADP_C10H12N5O10P2

242428
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stoichiometry: 1.0
species: 175770

242332
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stoichiometry: 1.0
species: 183892

183892
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Propanoyl-CoA_C24H36N7O17P3S

242319
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species: 175902

175902
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Bicarbonate_CHO3

242380
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species: 174986

174986
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: GMP_C10H12N5O8P

242356
type: SpeciesReference
stoichiometry: 1.0
species: 161660

161660
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3',5'-Cyclic GMP_C10H11N5O7P

242392
type: SpeciesReference
stoichiometry: 1.0
species: 181114

181114
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: (S)-Methylmalonyl-CoA_C25H35N7O19P3S

242404
type: SpeciesReference
stoichiometry: 1.0
species: 183700

183700
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Phosphate_HO4P

242344
type: SpeciesReference
stoichiometry: 1.0
species: 166928

166928
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: ATP_C10H12N5O13P3

242440
type: SpeciesReference
stoichiometry: 1.0
species: 175722

185423
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Selenate_O4Se

161551
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3,4-Dihydroxymandelaldehyde_C8H8O4

178087
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: keratan sulfate I_C247H393N17O213S12X

180403
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Malonyl-CoA_C24H33N7O19P3S

182479
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: octadecadienoate (n-C18:2)_C18H31O2

177664
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 17_C152H245N10O132S7

949187
type: Reaction
product: 224534
product: 224510
product: 224498
is: ENSMUSG00000002550.7
notes: R_URIK1 subsystem: Pyrimidine Biosynthesis R_URIK1 equation: [c] : atp + uri --> adp + h + ump R_CYTDK1 subsystem: Nucleotides R_CYTDK1 equation: [c] : atp + cytd --> adp + cmp + h
is: ENSMUSG00000026558.7
product: 224522
reactant: 224474
reversible: false
reactant: 224486
is: http://identifiers.org/ec-code/2.7.1.48
fast: false
reactant: 224461

224534
type: SpeciesReference
stoichiometry: 2.0
species: 175722

224510
type: SpeciesReference
stoichiometry: 1.0
species: 187851

187851
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: UMP_C9H11N2O9P

224498
type: SpeciesReference
stoichiometry: 1.0
species: 168316

168316
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: CMP_C9H12N3O8P

224522
type: SpeciesReference
stoichiometry: 2.0
species: 165387

165387
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: ADP_C10H12N5O10P2

224474
type: SpeciesReference
stoichiometry: 1.0
species: 169743

169743
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Cytidine_C9H13N3O5

224486
type: SpeciesReference
stoichiometry: 1.0
species: 188032

188032
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Uridine_C9H12N2O6

224461
type: SpeciesReference
stoichiometry: 2.0
species: 166904

166904
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: ATP_C10H12N5O13P3

188550
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: cholesterol ester_C27H45XCO2

180824
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Methylhistamine_C6H12N3

176565
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 19_C43H67N2O42S2

172535
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

187159
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: tolbutamide_C12H18N2O3S

953601
type: Reaction
product: 268256
is: http://identifiers.org/ec-code/4.4.1.1
fast: false
product: 268268
is: ENSMUSG00000028179.8
reversible: false
product: 268280
reactant: 268232
product: 268292
reactant: 268220
reactant: 268244
notes: R_SELCYSTGL subsystem: Selenoamino acid metabolism R_SELCYSTGL equation: [c] : h2o + selcyst --> 2obut + nh4 + selcys R_CYSTGL subsystem: Cysteine Metabolism R_CYSTGL equation: [c] : cyst-L + h2o --> 2obut + cys-L + nh4

268256
type: SpeciesReference
stoichiometry: 1.0
species: 169680

169680
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Cysteine_C3H7NO2S

268268
type: SpeciesReference
stoichiometry: 2.0
species: 161477

161477
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _2-Oxobutanoate_C4H5O3

268280
type: SpeciesReference
stoichiometry: 1.0
species: 185435

185435
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Selenocysteine_C3H7NO2Se

268232
type: SpeciesReference
stoichiometry: 1.0
species: 185447

185447
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Selenocystathionine_C7H14N2O4Se

268292
type: SpeciesReference
stoichiometry: 2.0
species: 181752

181752
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Ammonium_H4N

268220
type: SpeciesReference
stoichiometry: 1.0
species: 169731

169731
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Cystathionine_C7H14N2O4S

268244
type: SpeciesReference
stoichiometry: 2.0
species: 175614

168751
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

949680
type: Reaction
reactant: 228880
fast: false
name: Prostaglandin E synthase
reversible: true
notes: R_PGESr subsystem: Eicosanoid Metabolism R_PGESr equation: [r] : prostgh2 <==> prostge2
is: http://identifiers.org/ec-code/5.3.99.3
product: 228892
is: ENSMUSG00000026820.2
is: ENSMUSG00000027566.7

228880
type: SpeciesReference
stoichiometry: 1.0
species: 184531

184531
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Prostaglandin H2_C20H31O5

228892
type: SpeciesReference
stoichiometry: 1.0
species: 184483

184483
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Prostaglandin E2_C20H31O5

173838
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: galactocerebroside (homo sapiens)_C24H46NO7FULLRCO

186682
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Tetrahydrobiopterin_C9H15N5O3

945149
type: Reaction
notes: R_S2TASE2ly subsystem: Heparan sulfate degradation R_S2TASE2ly equation: [l] : h2o + hs_deg21 --> h + hs_deg22 + so4 R_S2TASE1ly subsystem: Heparan sulfate degradation R_S2TASE1ly equation: [l] : h2o + hs_deg15 --> h + hs_deg16 + so4 R_S2TASE3ly subsystem: Chondroitin sulfate degradation R_S2TASE3ly equation: [l] : cs_b_deg2 + h2o --> cs_b_deg3 + h + so4
product: 189032
reactant: 188972
product: 189044
is: http://identifiers.org/ec-code/3.1.6.13
reactant: 188996
product: 189068
reactant: 189008
product: 189056
fast: false
reactant: 188984
reversible: false
product: 189020
is: ENSMUSG00000035847.6

189032
type: SpeciesReference
stoichiometry: 3.0
species: 175758

175758
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: H+_H

188972
type: SpeciesReference
stoichiometry: 3.0
species: 175650

175650
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: H2O_H2O

189044
type: SpeciesReference
stoichiometry: 1.0
species: 169067

169067
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), degradation product 3_C37H55NO38S2

188996
type: SpeciesReference
stoichiometry: 1.0
species: 176517

176517
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 15_C49H71N2O57S5

189068
type: SpeciesReference
stoichiometry: 3.0
species: 185679

185679
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Sulfate_O4S

189008
type: SpeciesReference
stoichiometry: 1.0
species: 169055

169055
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), degradation product 2_C37H54NO41S3

189056
type: SpeciesReference
stoichiometry: 1.0
species: 176529

176529
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 16_C49H72N2O54S4

188984
type: SpeciesReference
stoichiometry: 1.0
species: 176601

176601
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 21_C37H55NO38S2

189020
type: SpeciesReference
stoichiometry: 1.0
species: 176613

176613
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 22_C37H56NO35S

186549
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: tetracosapentaenoyl coenzyme A, n-6_C45H68N7O17P3S

163221
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-Hydroxykynurenine_C10H12N2O4

182791
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

948442
type: Reaction
product: 217750
reactant: 217726
fast: false
is: ENSMUSG00000032889.5
reversible: false
reactant: 217714
product: 217762
name: L-Lactate dehydrogenase, cytosolic/mitochondrial
is: http://identifiers.org/ec-code/1.1.2.3
product: 217738
notes: R_L_DASH_LACDcm subsystem: Pyruvate Metabolism R_L_DASH_LACDcm equation: (2) ficytC[m] + lac-L[c] --> (2) focytC[m] + (2) h[c] + pyr[c]
is: ENSMUSG00000044795.5

217750
type: SpeciesReference
stoichiometry: 1.0
species: 184819

184819
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Pyruvate_C3H3O3

217726
type: SpeciesReference
stoichiometry: 1.0
species: 179086

179086
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Lactate_C3H5O3

217714
type: SpeciesReference
stoichiometry: 2.0
species: 172704

172704
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Ferricytochrome c_C42H54FeN8O6S2

217762
type: SpeciesReference
stoichiometry: 2.0
species: 175722

217738
type: SpeciesReference
stoichiometry: 2.0
species: 172752

172752
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Ferrocytochrome C_C42H54FeN8O6S2

175237
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Guanosine_C10H13N5O5

163896
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Histone N6-methyl-L-lysine_CXH4

162556
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _4-Hydroxybenzoate_C7H5O3

171595
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: dTDP_C10H13N2O11P2

188754
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Xylulose_C5H10O5

166279
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: AMP_C10H12N5O7P

178329
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 26_C199H318N14O166S8X

945806
type: Reaction
reactant: 194612
reversible: false
is: ENSMUSG00000026288.7
is: ENSMUSG00000032737.5
product: 194660
product: 194672
reactant: 194624
is: http://identifiers.org/ec-code/3.1.3.56
product: 194648
fast: false
is: ENSMUSG00000034570.4
notes: R_PI345P5P subsystem: Inositol Phosphate Metabolism R_PI345P5P equation: [c] : h2o + pail345p_hs --> pail34p_hs + pi R_MI145PP subsystem: Inositol Phosphate Metabolism R_MI145PP equation: [c] : h2o + mi145p --> mi14p + pi R_MI1345PP subsystem: Inositol Phosphate Metabolism R_MI1345PP equation: [c] : h2o + mi1345p --> mi134p + pi
product: 194636
reactant: 194599
reactant: 194587
is: ENSMUSG00000025477.6

194612
type: SpeciesReference
stoichiometry: 3.0
species: 175614

194660
type: SpeciesReference
stoichiometry: 3.0
species: 183652

183652
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Phosphate_HO4P

194672
type: SpeciesReference
stoichiometry: 1.0
species: 180945

180945
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1D-myo-Inositol 1,4-bisphosphate_C6H10O12P2

194624
type: SpeciesReference
stoichiometry: 1.0
species: 180861

180861
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1D-myo-Inositol 1,3,4,5-tetrakisphosphate_C6H8O18P4

194648
type: SpeciesReference
stoichiometry: 1.0
species: 180897

180897
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1D-myo-Inositol 1,3,4-trisphosphate_C6H9O15P3

194636
type: SpeciesReference
stoichiometry: 1.0
species: 182887

182887
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: phosphatidylinositol-3,4-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

194599
type: SpeciesReference
stoichiometry: 1.0
species: 180921

180921
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1D-myo-Inositol 1,4,5-trisphosphate_C6H9O15P3

194587
type: SpeciesReference
stoichiometry: 1.0
species: 182863

182863
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)_C9H13O18P4FULLRCO2FULLR2CO2

179231
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Leucine_C6H13NO2

165653
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Adenylylselenate_C10H12N5O10PSe

952759
type: Reaction
product: 260672
is: ENSMUSG00000031467.3
is: http://identifiers.org/ec-code/2.3.1.51
name: _1-acylglycerol-3-phosphate O-acyltransferase 1
is: ENSMUSG00000031545.3
is: ENSMUSG00000001211.6
reversible: false
notes: R_AGPAT1 subsystem: Triacylglycerol Synthesis R_AGPAT1 equation: [c] : Rtotal2coa + alpa_hs --> coa + pa_hs
reactant: 260660
is: ENSMUSG00000026922.5
product: 260684
fast: false
reactant: 260648
is: ENSMUSG00000023827.1

260672
type: SpeciesReference
stoichiometry: 1.0
species: 168509

168509
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Coenzyme A_C21H32N7O16P3S

260660
type: SpeciesReference
stoichiometry: 1.0
species: 164004

164004
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: R total 2 coenzyme A_CO2FULLR2C21H31N7O15P3S

260684
type: SpeciesReference
stoichiometry: 1.0
species: 182755

182755
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

260648
type: SpeciesReference
stoichiometry: 1.0
species: 166099

166099
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: lysophosphatidic acid (homo sapiens)_C3H6O5PFULLRCO2

948202
type: Reaction
product: 215809
reactant: 215797
notes: R_GLCAE2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAE2g equation: [g] : hs_pre10 --> hs_pre11
is: ENSMUSG00000032252.7
is: http://identifiers.org/ec-code/5.1.3.17
fast: false
reversible: false
name: heparosan-N-sulfate-glucuronate 5-epimerase

215809
type: SpeciesReference
stoichiometry: 1.0
species: 176782

176782
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: heparan sulfate, precursor 11_C79H121N5O77S4X

215797
type: SpeciesReference
stoichiometry: 1.0
species: 176770

176770
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: heparan sulfate, precursor 10_C79H121N5O77S4X

186308
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: taurocholic acid_C26H45NO7S

180716
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Mesaconyl-CoA_C26H35N7O19P3S

946759
type: Reaction
is: ENSMUSG00000063873.2
product: 203435
reversible: true
name: Na+/Ca2+-K+ exchange
product: 203423
reactant: 203387
reactant: 203399
is: ENSMUSG00000041771.4
reactant: 203411
notes: R_NCKt subsystem: Transport, Extracellular R_NCKt equation: ca2[e] + k[e] + (4) na1[c] <==> ca2[c] + k[c] + (4) na1[e]
product: 203447
fast: false

203435
type: SpeciesReference
stoichiometry: 1.0
species: 177531

177531
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: potassium_K

203423
type: SpeciesReference
stoichiometry: 1.0
species: 167459

167459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Calcium_Ca

203387
type: SpeciesReference
stoichiometry: 1.0
species: 167471

167471
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Calcium_Ca

203399
type: SpeciesReference
stoichiometry: 1.0
species: 177543

177543
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: potassium_K

203411
type: SpeciesReference
stoichiometry: 4.0
species: 181377

181377
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Sodium_Na

203447
type: SpeciesReference
stoichiometry: 4.0
species: 181389

181389
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Sodium_Na

176457
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 10_C55H80N3O70S8

171220
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: DNA 5-methylcytosine_C11H19O8PR2

163655
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heptaglutamyl folate (THF)_C49H57N13O24

949247
type: Reaction
fast: false
reactant: 224800
is: ENSMUSG00000027761.2
product: 224848
notes: R_EGMESTr subsystem: Alkaloid biosynthesis II R_EGMESTr equation: [r] : egme + h2o --> ecgon + h + meoh
product: 224836
reactant: 224812
reversible: false
product: 224824
name: ecgonine methyl esterase (ER)

224800
type: SpeciesReference
stoichiometry: 1.0
species: 171969

171969
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: ecgonine methyl ester_C10H17NO3

224848
type: SpeciesReference
stoichiometry: 1.0
species: 175794

175794
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: H+_H

224836
type: SpeciesReference
stoichiometry: 1.0
species: 171956

171956
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: ecgonine_C9H14NO3

224812
type: SpeciesReference
stoichiometry: 1.0
species: 175686

175686
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: H2O_H2O

224824
type: SpeciesReference
stoichiometry: 1.0
species: 180656

180656
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Methanol_CH4O1

947576
type: Reaction
reactant: 210789
reactant: 210813
is: http://identifiers.org/ec-code/2.6.1.7
notes: R_3HKYNAKGAT subsystem: Tryptophan metabolism R_3HKYNAKGAT equation: [c] : akg + hLkynr --> 42A3HP24DB + glu-L R_KYNAKGAT subsystem: Tryptophan metabolism R_KYNAKGAT equation: [c] : Lkynr + akg --> 4aphdob + glu-L
is: ENSMUSG00000039648.6
reversible: false
product: 210849
product: 210825
product: 210837
reactant: 210801
fast: false

210789
type: SpeciesReference
stoichiometry: 2.0
species: 165871

165871
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _2-Oxoglutarate_C5H4O5

210813
type: SpeciesReference
stoichiometry: 1.0
species: 163835

163835
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Kynurenine_C10H12N2O3

210849
type: SpeciesReference
stoichiometry: 1.0
species: 162350

162350
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate_C10H8NO5

210825
type: SpeciesReference
stoichiometry: 1.0
species: 162508

162508
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-(2-Aminophenyl)-2,4-dioxobutanoate_C10H8NO4

210837
type: SpeciesReference
stoichiometry: 2.0
species: 174442

174442
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Glutamate_C5H8NO4

210801
type: SpeciesReference
stoichiometry: 1.0
species: 175710

175710
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Hydroxy-L-kynurenine_C10H12N2O4

955559
type: Reaction
product: 288686
reactant: 288638
is: ENSMUSG00000022561.5
product: 288722
is: ENSMUSG00000038383.7
reactant: 288626
is: ENSMUSG00000041958.7
reactant: 288662
fast: false
notes: R_M4BTAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4BTAer equation: [r] : mem2emgacpail_hs + pre_prot --> gpi_sig + mem2emgacpail_prot_hs R_H8TAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8TAer equation: [r] : gpi_hs + pre_prot --> gpi_prot_hs + gpi_sig R_M4ATAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4ATAer equation: [r] : m(em)3gacpail_hs + pre_prot --> gpi_sig + m(em)3gacpail_prot_hs R_H7_APOS_TAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7_APOS_TAer equation: [r] : em2emgacpail_hs + pre_prot --> em2emgacpail_prot_hs + gpi_sig
reversible: false
product: 288734
reactant: 288650
is: ENSMUSG00000039047.8
product: 288710
product: 288698
reactant: 288674

288686
type: SpeciesReference
stoichiometry: 4.0
species: 175133

175133
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: glycophosphatidylinositol (GPI) signal sequence (C-terminal peptide)_Y

288638
type: SpeciesReference
stoichiometry: 1.0
species: 172077

172077
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (phosphoethanolaminyl-dimannosyl),(phosphoethanolaminyl)-mannosyl-glucosaminyl-acylphosphatidylinositol (H7)_C53H100N3O35P3FULLRCO2FULLR2CO2

288722
type: SpeciesReference
stoichiometry: 1.0
species: 180294

180294
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: mannosyl-3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol-Protein (M4A)_C61H116N4O43P4FULLRCO2FULLR2CO2X

288626
type: SpeciesReference
stoichiometry: 1.0
species: 180282

288662
type: SpeciesReference
stoichiometry: 1.0
species: 175108

175108
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: glycophosphatidylinositol (GPI) anchor precursor (3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol) (H8)_C55H106N4O38P4FULLRCO2FULLR2CO2

288734
type: SpeciesReference
stoichiometry: 1.0
species: 180608

180608
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: ({[(mannosyl),(phosphoethanolaminyl)]-dimannosyl},{phosphoethanolaminyl})-mannosyl-glucosaminyl-acylphosphatidylinositol-Protein (M4B)_C59H110N3O40P3FULLRCO2FULLR2CO2X

288650
type: SpeciesReference
stoichiometry: 4.0
species: 184110

184110
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: glycophosphatidylinositol (GPI)-anchored protein precursor_XY

288710
type: SpeciesReference
stoichiometry: 1.0
species: 172089

172089
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526

288698
type: SpeciesReference
stoichiometry: 1.0
species: 175121

175121
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: glycophosphatidylinositol (GPI)-anchored protein_C55H106N4O38P4FULLRCO2FULLR2CO2X

288674
type: SpeciesReference
stoichiometry: 1.0
species: 180596

180596
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: ({[(mannosyl),(phosphoethanolaminyl)]-dimannosyl},{phosphoethanolaminyl})-mannosyl-glucosaminyl-acylphosphatidylinositol (M4B)_C59H110N3O40P3FULLRCO2FULLR2CO2

187948
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Uracil_C4H4N2O2

183216
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Procollagen 5-hydroxy-L-lysine_C6H14N2O3

181571
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

163185
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-Hydroxy-N-formylkynurenine_C11H12N2O5

182683
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Ornithine_C5H13N2O2

173972
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: glycocholate_C26H43NO6

174310
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: D-Glucose_C6H12O6

177869
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 31_C90H148N6O72S2

178870
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate II (core 4-linked)_C89H142N7O72S3X

947252
type: Reaction
is: http://identifiers.org/ec-code/2.5.1.26
is: ENSMUSG00000042410.6
notes: R_AGPSx subsystem: Glycerophospholipid Metabolism R_AGPSx equation: [x] : adhap_hs + alkylR1oh --> Rtotal + akdhap_hs + h
product: 207984
reactant: 207948
product: 207996
fast: false
reactant: 207960
name: alkylglycerone phosphate synthase
reversible: false
product: 207972

207984
type: SpeciesReference
stoichiometry: 1.0
species: 164162

164162
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: R total_CO2FULLR

207948
type: SpeciesReference
stoichiometry: 1.0
species: 166087

166087
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: hydroxy alkyl chain_C2H5OFULLR

207996
type: SpeciesReference
stoichiometry: 1.0
species: 175806

175806
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: H+_H

207960
type: SpeciesReference
stoichiometry: 1.0
species: 165308

165308
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: acyl-dihydroxyacetone phosphate_C3H4O6PFULLRCO

207972
type: SpeciesReference
stoichiometry: 1.0
species: 165859

165859
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: _1-alkyldihydroxyacetone phosphate_C3H4O6PFULLRC2H4

188646
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Xyl-L-Ser (protein)_C5H9O4X

955235
type: Reaction
product: 283599
reactant: 283490
product: 283818
reactant: 283369
reactant: 283466
reactant: 283454
product: 283635
is: http://identifiers.org/ec-code/6.3.2.17
reactant: 283418
reactant: 283356
is: ENSMUSG00000021680.7
product: 283708
reactant: 283442
product: 283587
reactant: 283430
product: 283769
reactant: 283381
product: 283720
product: 283830
product: 283672
product: 283782
reactant: 283331
reactant: 283307
reactant: 283563
reactant: 283319
reactant: 283478
fast: false
reactant: 283343
product: 283659
reactant: 283527
product: 283744
reactant: 283539
reactant: 283393
product: 283696
product: 283611
product: 283732
reversible: false
product: 283842
product: 283684
product: 283623
reactant: 283514
product: 283794
product: 283854
reactant: 283502
product: 283575
product: 283647
reactant: 283551
product: 283806
notes: R_FPGS subsystem: Folate Metabolism R_FPGS equation: [c] : (4) atp + (4) glu-L + thf --> 5thf + (4) adp + (4) h + (4) pi R_FPGS9 subsystem: Folate Metabolism R_FPGS9 equation: [c] : 10fthf6glu + atp + glu-L --> 10fthf7glu + adp + h + pi R_FPGS3m subsystem: Folate Metabolism R_FPGS3m equation: [m] : 6thf + atp + glu-L --> 7thf + adp + h + pi R_FPGS7 subsystem: Folate Metabolism R_FPGS7 equation: [c] : 10fthf + (4) atp + (4) glu-L --> 10fthf5glu + (4) adp + (4) h + (4) pi R_FPGSm subsystem: Folate Metabolism R_FPGSm equation: [m] : (4) atp + (4) glu-L + thf --> 5thf + (4) adp + (4) h + (4) pi R_FPGS4 subsystem: Folate Metabolism R_FPGS4 equation: [c] : (4) atp + dhf + (4) glu-L --> 5dhf + (4) adp + (4) h + (4) pi R_FPGS4m subsystem: Folate Metabolism R_FPGS4m equation: [m] : (4) atp + dhf + (4) glu-L --> 5dhf + (4) adp + (4) h + (4) pi R_FPGS6 subsystem: Folate Metabolism R_FPGS6 equation: [c] : 6dhf + atp + glu-L --> 7dhf + adp + h + pi R_FPGS3 subsystem: Folate Metabolism R_FPGS3 equation: [c] : 6thf + atp + glu-L --> 7thf + adp + h + pi R_FPGS5m subsystem: Folate Metabolism R_FPGS5m equation: [m] : 5dhf + atp + glu-L --> 6dhf + adp + h + pi R_FPGS2m subsystem: Folate Metabolism R_FPGS2m equation: [m] : 5thf + atp + glu-L --> 6thf + adp + h + pi R_FPGS8 subsystem: Folate Metabolism R_FPGS8 equation: [c] : 10fthf5glu + atp + glu-L --> 10fthf6glu + adp + h + pi R_FPGS2 subsystem: Folate Metabolism R_FPGS2 equation: [c] : 5thf + atp + glu-L --> 6thf + adp + h + pi R_FPGS7m subsystem: Folate Metabolism R_FPGS7m equation: [m] : 10fthf + (4) atp + (4) glu-L --> 10fthf5glu + (4) adp + (4) h + (4) pi R_FPGS6m subsystem: Folate Metabolism R_FPGS6m equation: [m] : 6dhf + atp + glu-L --> 7dhf + adp + h + pi R_FPGS9m subsystem: Folate Metabolism R_FPGS9m equation: [m] : 10fthf6glu + atp + glu-L --> 10fthf7glu + adp + h + pi R_FPGS8m subsystem: Folate Metabolism R_FPGS8m equation: [m] : 10fthf5glu + atp + glu-L --> 10fthf6glu + adp + h + pi R_FPGS5 subsystem: Folate Metabolism R…
product: 283756
reactant: 283405

283599
type: SpeciesReference
stoichiometry: 1.0
species: 163559

163559
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: hexaglutamyl folate (THF)_C44H51N12O21

283490
type: SpeciesReference
stoichiometry: 18.0
species: 166928

283818
type: SpeciesReference
stoichiometry: 1.0
species: 163631

163631
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: heptaglutamyl folate (THF)_C49H57N13O24

283369
type: SpeciesReference
stoichiometry: 1.0
species: 163329

163329
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: pentaglutamyl folate (THF)_C39H45N11O18

283466
type: SpeciesReference
stoichiometry: 18.0
species: 174478

174478
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Glutamate_C5H8NO4

283454
type: SpeciesReference
stoichiometry: 1.0
species: 163414

163414
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: haxglutamyl folate (DHF)_C44H49N12O21

283635
type: SpeciesReference
stoichiometry: 1.0
species: 163015

163015
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: pentaglutamyl folate (DHF)_C39H43N11O18

283418
type: SpeciesReference
stoichiometry: 1.0
species: 170834

170834
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _7,8-Dihydrofolate_C19H19N7O6

283356
type: SpeciesReference
stoichiometry: 1.0
species: 163015

283708
type: SpeciesReference
stoichiometry: 1.0
species: 163378

163378
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: haxglutamyl folate (DHF)_C44H49N12O21

283442
type: SpeciesReference
stoichiometry: 18.0
species: 174442

283587
type: SpeciesReference
stoichiometry: 1.0
species: 160659

160659
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _10-formyltetrahydrofolate-[Glu](6)_C45H51N12O22

283430
type: SpeciesReference
stoichiometry: 1.0
species: 163378

283769
type: SpeciesReference
stoichiometry: 1.0
species: 160647

160647
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19

283381
type: SpeciesReference
stoichiometry: 18.0
species: 166904

283720
type: SpeciesReference
stoichiometry: 1.0
species: 160707

160707
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _10-formyltetrahydrofolate-[Glu](7)_C50H57N13O25

283830
type: SpeciesReference
stoichiometry: 18.0
species: 175770

283672
type: SpeciesReference
stoichiometry: 18.0
species: 183700

283782
type: SpeciesReference
stoichiometry: 1.0
species: 160695

160695
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _10-formyltetrahydrofolate-[Glu](6)_C45H51N12O22

283331
type: SpeciesReference
stoichiometry: 1.0
species: 186792

186792
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5,6,7,8-Tetrahydrofolate_C19H21N7O6

283307
type: SpeciesReference
stoichiometry: 1.0
species: 163523

163523
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: hexaglutamyl folate (THF)_C44H51N12O21

283563
type: SpeciesReference
stoichiometry: 1.0
species: 160758

160758
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _10-Formyltetrahydrofolate_C20H21N7O7

283319
type: SpeciesReference
stoichiometry: 1.0
species: 160659

283478
type: SpeciesReference
stoichiometry: 1.0
species: 160647

283343
type: SpeciesReference
stoichiometry: 1.0
species: 163559

283659
type: SpeciesReference
stoichiometry: 1.0
species: 163329

283527
type: SpeciesReference
stoichiometry: 1.0
species: 160797

160797
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _10-Formyltetrahydrofolate_C20H21N7O7

283744
type: SpeciesReference
stoichiometry: 1.0
species: 163414

283539
type: SpeciesReference
stoichiometry: 1.0
species: 163052

163052
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: pentaglutamyl folate (DHF)_C39H43N11O18

283393
type: SpeciesReference
stoichiometry: 1.0
species: 170797

170797
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _7,8-Dihydrofolate_C19H19N7O6

283696
type: SpeciesReference
stoichiometry: 1.0
species: 160611

160611
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19

283611
type: SpeciesReference
stoichiometry: 1.0
species: 163619

163619
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: heptaglutamyl folate (DHF)_C49H55N13O24

283732
type: SpeciesReference
stoichiometry: 18.0
species: 165387

283842
type: SpeciesReference
stoichiometry: 18.0
species: 175722

283684
type: SpeciesReference
stoichiometry: 18.0
species: 165411

283623
type: SpeciesReference
stoichiometry: 18.0
species: 183652

283514
type: SpeciesReference
stoichiometry: 1.0
species: 186828

186828
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _5,6,7,8-Tetrahydrofolate_C19H21N7O6

283794
type: SpeciesReference
stoichiometry: 1.0
species: 163583

163583
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: heptaglutamyl folate (DHF)_C49H55N13O24

283854
type: SpeciesReference
stoichiometry: 1.0
species: 163366

163366
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: pentaglutamyl folate (THF)_C39H45N11O18

283502
type: SpeciesReference
stoichiometry: 1.0
species: 160695

283575
type: SpeciesReference
stoichiometry: 1.0
species: 163523

283647
type: SpeciesReference
stoichiometry: 1.0
species: 163667

163667
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: heptaglutamyl folate (THF)_C49H57N13O24

283551
type: SpeciesReference
stoichiometry: 1.0
species: 163366

283806
type: SpeciesReference
stoichiometry: 1.0
species: 163052

283756
type: SpeciesReference
stoichiometry: 1.0
species: 160745

160745
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _10-formyltetrahydrofolate-[Glu](7)_C50H57N13O25

283405
type: SpeciesReference
stoichiometry: 1.0
species: 160611

161501
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _2-Oxoadipate_C6H6O5

165545
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: adrenic acid_C22H35O2

951569
type: Reaction
notes: R_GLCNACPT_U subsystem: N-Glycan Biosynthesis R_GLCNACPT_U equation: [c] : (0.1) dolp_U + uacgam --> (0.1) naglc2p_U + ump R_GLCNACPT_L subsystem: N-Glycan Biosynthesis R_GLCNACPT_L equation: [c] : (0.1) dolp_L + uacgam --> (0.1) naglc2p_L + ump
product: 247158
fast: false
reversible: false
reactant: 247121
product: 247146
is: http://identifiers.org/ec-code/2.7.8.15
is: ENSMUSG00000032123.4
reactant: 247097
product: 247134
reactant: 247109

247158
type: SpeciesReference
stoichiometry: 1.0
species: 181692

181692
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Acetyl-D-glucosaminyldiphosphodolichol, human liver homolog_C1160H1898N10O120P20

247121
type: SpeciesReference
stoichiometry: 2.0
species: 187560

187560
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514

247146
type: SpeciesReference
stoichiometry: 2.0
species: 187851

247097
type: SpeciesReference
stoichiometry: 1.0
species: 171403

171403
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Dolichol phosphate, human liver homolog_C1080H1758O40P10

247134
type: SpeciesReference
stoichiometry: 1.0
species: 181704

181704
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Acetyl-D-glucosaminyldiphosphodolichol, human uterine homolog_C1105H1810N10O120P20

247109
type: SpeciesReference
stoichiometry: 1.0
species: 171427

171427
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Dolichol phosphate, human uterine homolog_C1025H1670O40P10

168208
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Chloride_Cl

955511
type: Reaction
reactant: 288155
product: 288239
reactant: 288203
reactant: 288191
is: http://identifiers.org/ec-code/3.1.3.5
is: ENSMUSG00000020736.5
product: 288227
reactant: 288167
reactant: 288215
notes: R_NTD5 subsystem: Pyrimidine Catabolism R_NTD5 equation: [c] : dtmp + h2o --> pi + thymd R_NTD1 subsystem: Pyrimidine Catabolism R_NTD1 equation: [c] : dump + h2o --> duri + pi R_NTD3 subsystem: Pyrimidine Catabolism R_NTD3 equation: [c] : dcmp + h2o --> dcyt + pi R_NTD8 subsystem: Nucleotides R_NTD8 equation: [c] : dgmp + h2o --> dgsn + pi R_NTD12 subsystem: Nucleotides R_NTD12 equation: [c] : dimp + h2o --> din + pi
reversible: false
product: 288275
product: 288263
fast: false
product: 288288
reactant: 288179
product: 288251

288155
type: SpeciesReference
stoichiometry: 1.0
species: 170447

170447
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dGMP_C10H12N5O7P

288239
type: SpeciesReference
stoichiometry: 1.0
species: 170979

170979
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Deoxyinosine_C10H12N4O4

288203
type: SpeciesReference
stoichiometry: 5.0
species: 175614

288191
type: SpeciesReference
stoichiometry: 1.0
species: 171620

171620
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dTMP_C10H13N2O8P

288227
type: SpeciesReference
stoichiometry: 1.0
species: 171788

171788
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Deoxyuridine_C9H12N2O5

288167
type: SpeciesReference
stoichiometry: 1.0
species: 170967

170967
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dIMP_C10H11N4O7P

288215
type: SpeciesReference
stoichiometry: 1.0
species: 170073

170073
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dCMP_C9H12N3O7P

288275
type: SpeciesReference
stoichiometry: 1.0
species: 170218

170218
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Deoxycytidine_C9H13N3O4

288263
type: SpeciesReference
stoichiometry: 1.0
species: 186984

186984
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Thymidine_C10H14N2O5

288288
type: SpeciesReference
stoichiometry: 1.0
species: 170496

170496
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Deoxyguanosine_C10H13N5O4

288179
type: SpeciesReference
stoichiometry: 1.0
species: 171752

171752
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dUMP_C9H11N2O8P

288251
type: SpeciesReference
stoichiometry: 5.0
species: 183652

166063
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: L-Alanine_C3H7NO2

160635
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19

182912
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: phosphatidylinositol-3,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

177071
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Isobutyryl-CoA_C25H38N7O17P3S

170688
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598

186960
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Thymine_C5H6N2O2

180500
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Mannose 6-phosphate_C6H11O9P

176649
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 25_C23H37O21

161489
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _2-Oxoadipate_C6H6O5

168605
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Core 2_C22H37N2O15X

163968
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: R group 2 Coenzyme A homo sapiens_XCO2C21H31N7O15P3S

950918
type: Reaction
fast: false
is: ENSMUSG00000055368.6
notes: R_NRPPHRt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_NRPPHRt4_LPAREN_2_RPAREN_r equation: (2) na1[e] + nrpphr[e] <==> (2) na1[c] + nrpphr[c] R_DOPAt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_DOPAt4_LPAREN_2_RPAREN_r equation: dopa[e] + (2) na1[e] <==> dopa[c] + (2) na1[c]
product: 242283
reactant: 242270
product: 242307
reactant: 242257
reactant: 242243
is: ENSMUSG00000021609.6
reversible: true
product: 242295

242283
type: SpeciesReference
stoichiometry: 1.0
species: 182008

182008
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Norepinephrine_C8H12NO3

242270
type: SpeciesReference
stoichiometry: 1.0
species: 182020

182020
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Norepinephrine_C8H12NO3

242307
type: SpeciesReference
stoichiometry: 1.0
species: 171451

171451
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Dopamine_C8H12NO2

242257
type: SpeciesReference
stoichiometry: 4.0
species: 181389

242243
type: SpeciesReference
stoichiometry: 1.0
species: 171463

171463
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Dopamine_C8H12NO2

242295
type: SpeciesReference
stoichiometry: 4.0
species: 181377

161648
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3-(4-Hydroxyphenyl)pyruvate_C9H7O4

953037
type: Reaction
is: ENSMUSG00000040618.4
product: 263834
is: http://identifiers.org/ec-code/4.1.1.32
product: 263822
reactant: 263798
notes: R_PEPCKm subsystem: Glycolysis/Gluconeogenesis R_PEPCKm equation: [m] : gtp + oaa --> co2 + gdp + pep
product: 263846
fast: false
name: Phosphoenolpyruvate carboxykinase (GTP)
reversible: false
reactant: 263810

263834
type: SpeciesReference
stoichiometry: 1.0
species: 168461

168461
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: CO2_CO2

263822
type: SpeciesReference
stoichiometry: 1.0
species: 183373

183373
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Phosphoenolpyruvate_C3H2O6P

263798
type: SpeciesReference
stoichiometry: 1.0
species: 182298

182298
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Oxaloacetate_C4H2O5

263846
type: SpeciesReference
stoichiometry: 1.0
species: 174154

174154
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: GDP_C10H12N5O11P2

263810
type: SpeciesReference
stoichiometry: 1.0
species: 175458

175458
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: GTP_C10H12N5O14P3

174202
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GDP-L-fucose_C16H23N5O15P2

949415
type: Reaction
reactant: 226950
product: 227010
is: http://identifiers.org/ec-code/2.1.1.17
reactant: 226974
reactant: 226962
product: 226986
is: ENSMUSG00000000301.7
product: 227034
product: 227022
product: 226998
reversible: false
notes: R_PETOHMm_hs subsystem: Glycerophospholipid Metabolism R_PETOHMm_hs equation: [m] : (3) amet + pe_hs --> (3) ahcys + (3) h + pchol_hs R_PETOHMr_hs subsystem: Glycerophospholipid Metabolism R_PETOHMr_hs equation: [r] : (3) amet + pe_hs --> (3) ahcys + (3) h + pchol_hs
fast: false
product: 227046
reactant: 226938

226950
type: SpeciesReference
stoichiometry: 3.0
species: 166171

166171
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: S-Adenosyl-L-methionine_C15H23N6O5S

227010
type: SpeciesReference
stoichiometry: 1.0
species: 183192

183192
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

226974
type: SpeciesReference
stoichiometry: 3.0
species: 166195

166195
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: S-Adenosyl-L-methionine_C15H23N6O5S

226962
type: SpeciesReference
stoichiometry: 1.0
species: 183337

183337
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2

226986
type: SpeciesReference
stoichiometry: 3.0
species: 165749

165749
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

227034
type: SpeciesReference
stoichiometry: 3.0
species: 175770

227022
type: SpeciesReference
stoichiometry: 3.0
species: 175794

226998
type: SpeciesReference
stoichiometry: 3.0
species: 165773

165773
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

227046
type: SpeciesReference
stoichiometry: 1.0
species: 183204

183204
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

226938
type: SpeciesReference
stoichiometry: 1.0
species: 183325

183325
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2

186162
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Succinic semialdehyde_C4H5O3

172632
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Fructose 1,6-bisphosphate_C6H10O12P2

183796
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Palmitoylcarnitine_C23H45NO4

175010
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GMP_C10H12N5O8P

181873
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: nifedipine_C17H18N2O6

182875
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)_C9H13O18P4FULLRCO2FULLR2CO2

186646
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Tetracosatetraenoyl carnitine_C31H53NO4

169212
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate C (GalNAc6S-GlcA), precursor 3_C45H67N2O42S2X

173137
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)2 (Cer)1_C84H145N4O50FULLRCO

950846
type: Reaction
reactant: 241269
reversible: false
product: 241389
reactant: 241196
reactant: 241329
fast: false
notes: R_34DHXMANDACOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_34DHXMANDACOX_LPAREN_NADP_RPAREN_ equation: [c] : 34dhmald + h2o + nadp <==> 34dhoxmand + (2) h + nadph R_ALDD2y subsystem: Glycolysis/Gluconeogenesis R_ALDD2y equation: [c] : acald + h2o + nadp --> ac + (2) h + nadph R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD19x_LPAREN_P_RPAREN_ subsystem: Phenylalanine metabolism R_ALDD19x_LPAREN_P_RPAREN_ equation: [c] : h2o + nadp + pacald --> (2) h + nadph + pac R_34DHPLACOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_34DHPLACOX_LPAREN_NADP_RPAREN_ equation: [c] : 34dhpac + h2o + nadp <==> 34dhpha + (2) h + nadph R_3MOX4HOXPGALDOX subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX equation: [c] : 3m4hpga + h2o + nad --> 3mox4hoxm + (2) h + nadh R_MACOXO subsystem: Histidine Metabolism R_MACOXO equation: [c] : 3mldz + h2o + nad --> 3mlda + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_4HOXPACDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_4HOXPACDOX_LPAREN_NADP_RPAREN_ equation: [c] : 4hoxpacd + h2o + nadp <==> 4hphac + (2) h + nadph R_3M4HDXPAC subsystem: Tyrosine metabolism R_3M4HDXPAC equation: [c] : 3mox4hpac + h2o + nad <==> (2) h + homoval + nadh R_34DHPLACOX subsystem: Tyrosine metabolism R_34DHPLACOX equation: [c] : 34dhpac + h2o + nad --> 34dhpha + (2) h + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ equation: [c] : 3m4hpga + h2o + nadp <==> 3mox4hoxm + (2) h + nadph R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_ALDD19x subsystem: Phenylalanine metabolism R_ALDD19x equation: [c] : h2o + nad + pacald --> (2) h + nadh + pac R_GCALDD subsy…
product: 241353
modifier: 241559
product: 241401
is: http://identifiers.org/ec-code/1.2.1.3
reactant: 241281
reactant: 241208
reactant: 241293
is: ENSMUSG00000037263.5
product: 241449
modifier: 241572
product: 241377
is: ENSMUSG00000024885.6
product: 241425
is: http://identifiers.org/ec-code/1.2.1.5
is: http://identifiers.org/ec-code/1.2.1.4
is: ENSMUSG00000019102.3
modifier: 241632
reactant: 241221
modifier: 241522
reactant: 241305
modifier: 241644
reactant: 241233
modifier: 241534
modifier: 241656
product: 241474
modifier: 241668
is: ENSMUSG00000010025.9
modifier: 241510
reactant: 241245
is: http://identifiers.org/ec-code/1.2.1.21
reactant: 241257
modifier: 241608
modifier: 241620
is: http://identifiers.org/ec-code/1.2.1.39
modifier: 241547
product: 241437
modifier: 241680
product: 241365
modifier: 241498
product: 241341
product: 241413
modifier: 241584
modifier: 241596
reactant: 241184
reactant: 241317
product: 241486
product: 241462

241269
type: SpeciesReference
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species: 181558

241389
type: SpeciesReference
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species: 161599

161599
type: Species
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initial concentration: NaN
initial amount: NaN
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name: _3,4-Dihydroxyphenylacetate_C8H7O4

241196
type: SpeciesReference
stoichiometry: 1.0
species: 179146

179146
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Lactaldehyde_C3H6O2

241329
type: SpeciesReference
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species: 161551

241353
type: SpeciesReference
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species: 164438

164438
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Acetate_C2H3O2

161563
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3,4-Dihydroxymandelate_C8H7O5

241401
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species: 162047

162047
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Methylimidazoleacetic acid_C6H7N2O2

241281
type: SpeciesReference
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species: 182827

182827
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Phenylacetaldehyde_C8H8O

241208
type: SpeciesReference
stoichiometry: 10.0
species: 181437

181437
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

241293
type: SpeciesReference
stoichiometry: 13.0
species: 175614

241449
type: SpeciesReference
stoichiometry: 25.0
species: 175722

241377
type: SpeciesReference
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species: 161563

241425
type: SpeciesReference
stoichiometry: 1.0
species: 179086

241221
type: SpeciesReference
stoichiometry: 1.0
species: 173947

173947
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Glycolaldehyde_C2H4O2

241305
type: SpeciesReference
stoichiometry: 1.0
species: 174250

174250
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-glucurono-6,3-lactone_C6H8O6

162120
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Methoxy-4-hydroxymandelate_C9H9O5

241233
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species: 161587

161587
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3,4-Dihydroxyphenylacetaldehyde_C8H8O3

162592
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-Hydroxyphenylacetaldehyde_C8H8O2

241474
type: SpeciesReference
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species: 181510

181510
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

176361
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Homovanillate_C9H9O4

241245
type: SpeciesReference
stoichiometry: 2.0
species: 164534

164534
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Acetaldehyde_C2H4O

241257
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stoichiometry: 1.0
species: 162011

162011
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Methoxy-4-hydroxyphenylglycolaldehyde_C9H10O4

162604
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-Hydroxyphenylacetate_C8H7O3

241437
type: SpeciesReference
stoichiometry: 1.0
species: 179050

179050
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Lactate_C3H5O3

241365
type: SpeciesReference
stoichiometry: 1.0
species: 174334

174334
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Glucarate_C6H8O8

162132
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Methoxy-4-hydroxyphenylacetaldehyde_C9H10O3

241341
type: SpeciesReference
stoichiometry: 1.0
species: 174805

174805
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Glycolate_C2H3O3

241413
type: SpeciesReference
stoichiometry: 2.0
species: 182816

182816
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Phenylacetic acid_C8H7O2

241184
type: SpeciesReference
stoichiometry: 1.0
species: 162059

162059
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Methylimidazole acetaldehyde_C6H8N2O

241317
type: SpeciesReference
stoichiometry: 1.0
species: 179122

179122
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Lactaldehyde_C3H6O2

241486
type: SpeciesReference
stoichiometry: 2.0
species: 181631

241462
type: SpeciesReference
stoichiometry: 1.0
species: 162120

952495
type: Reaction
reactant: 257585
product: 257757
notes: R_NDPK9 subsystem: Nucleotides R_NDPK9 equation: [c] : atp + idp <==> adp + itp R_NDPK8 subsystem: Nucleotides R_NDPK8 equation: [c] : atp + dadp <==> adp + datp R_NDPK2 subsystem: Nucleotides R_NDPK2 equation: [c] : atp + udp <==> adp + utp R_NDPK6 subsystem: Nucleotides R_NDPK6 equation: [c] : atp + dudp <==> adp + dutp R_NDPK5 subsystem: Nucleotides R_NDPK5 equation: [c] : atp + dgdp <==> adp + dgtp R_NDPK3 subsystem: Nucleotides R_NDPK3 equation: [c] : atp + cdp <==> adp + ctp R_NDPK4 subsystem: Nucleotides R_NDPK4 equation: [c] : atp + dtdp <==> adp + dttp R_NDPK1 subsystem: Nucleotides R_NDPK1 equation: [c] : atp + gdp <==> adp + gtp R_NDPK7 subsystem: Nucleotides R_NDPK7 equation: [c] : atp + dcdp <==> adp + dctp R_NDPK10 subsystem: Nucleotides R_NDPK10 equation: [c] : atp + didp <==> adp + ditp
product: 257830
product: 257793
reversible: true
reactant: 257621
reactant: 257609
reactant: 257597
reactant: 257707
reactant: 257670
product: 257805
fast: false
is: http://identifiers.org/ec-code/2.7.4.6
product: 257842
reactant: 257633
product: 257720
reactant: 257695
reactant: 257683
product: 257732
is: ENSMUSG00000026575.8
product: 257745
is: ENSMUSG00000032478.4
reactant: 257658
product: 257817
product: 257769
reactant: 257645
product: 257781

257585
type: SpeciesReference
stoichiometry: 1.0
species: 170894

170894
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dIDP_C10H11N4O10P2

257757
type: SpeciesReference
stoichiometry: 10.0
species: 165387

257830
type: SpeciesReference
stoichiometry: 1.0
species: 188092

188092
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: UTP_C9H11N2O15P3

257793
type: SpeciesReference
stoichiometry: 1.0
species: 171003

171003
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dITP_C10H11N4O13P3

257621
type: SpeciesReference
stoichiometry: 1.0
species: 169841

169841
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dADP_C10H12N5O9P2

257609
type: SpeciesReference
stoichiometry: 10.0
species: 166904

257597
type: SpeciesReference
stoichiometry: 1.0
species: 174118

174118
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: GDP_C10H12N5O11P2

257707
type: SpeciesReference
stoichiometry: 1.0
species: 167651

167651
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: CDP_C9H12N3O11P2

257670
type: SpeciesReference
stoichiometry: 1.0
species: 187584

187584
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: UDP_C9H11N2O12P2

257805
type: SpeciesReference
stoichiometry: 1.0
species: 170181

170181
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dCTP_C9H12N3O13P3

257842
type: SpeciesReference
stoichiometry: 1.0
species: 177483

177483
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: ITP_C10H11N4O14P3

257633
type: SpeciesReference
stoichiometry: 1.0
species: 171716

171716
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dUDP_C9H11N2O11P2

257720
type: SpeciesReference
stoichiometry: 1.0
species: 171824

171824
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dUTP_C9H11N2O14P3

257695
type: SpeciesReference
stoichiometry: 1.0
species: 170411

170411
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dGDP_C10H12N5O10P2

257683
type: SpeciesReference
stoichiometry: 1.0
species: 170024

170024
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dCDP_C9H12N3O10P2

257732
type: SpeciesReference
stoichiometry: 1.0
species: 171680

171680
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dTTP_C10H13N2O14P3

257745
type: SpeciesReference
stoichiometry: 1.0
species: 169951

169951
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dATP_C10H12N5O12P3

257658
type: SpeciesReference
stoichiometry: 1.0
species: 177167

177167
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: IDP_C10H11N4O11P2

257817
type: SpeciesReference
stoichiometry: 1.0
species: 169615

169615
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: CTP_C9H12N3O14P3

257769
type: SpeciesReference
stoichiometry: 1.0
species: 175434

175434
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: GTP_C10H12N5O14P3

257645
type: SpeciesReference
stoichiometry: 1.0
species: 171571

171571
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dTDP_C10H13N2O11P2

257781
type: SpeciesReference
stoichiometry: 1.0
species: 170532

170532
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dGTP_C10H12N5O13P3

171692
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: dTTP_C10H13N2O14P3

166688
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: C20:4 carnitine_C27H45NO4

177313
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: IMP_C10H11N4O8P

182779
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2

178966
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 7_C75H121N6O56SX

945545
type: Reaction
reactant: 192447
product: 192543
is: ENSMUSG00000052738.4
product: 192519
reversible: true
reactant: 192495
reactant: 192459
product: 192579
notes: R_SUCOASm subsystem: Citric Acid Cycle R_SUCOASm equation: [m] : atp + coa + succ <==> adp + pi + succoa R_SUCOAS1m subsystem: Citric Acid Cycle R_SUCOAS1m equation: [m] : coa + gtp + succ <==> gdp + pi + succoa R_MECOAS1m subsystem: C5-Branched dibasic acid metabolism R_MECOAS1m equation: [m] : coa + gtp + mescon <==> gdp + mescoa + pi R_MECOALm subsystem: C5-Branched dibasic acid metabolism R_MECOALm equation: [m] : atp + coa + mescon <==> adp + mescoa + pi R_ITCOALm subsystem: C5-Branched dibasic acid metabolism R_ITCOALm equation: [m] : atp + coa + itacon <==> adp + itaccoa + pi R_ITCOAL1m subsystem: C5-Branched dibasic acid metabolism R_ITCOAL1m equation: [m] : coa + gtp + itacon <==> gdp + itaccoa + pi
product: 192555
fast: false
product: 192531
reactant: 192507
is: http://identifiers.org/ec-code/6.2.1.4
reactant: 192483
product: 192567
is: http://identifiers.org/ec-code/6.2.1.5
reactant: 192471

192447
type: SpeciesReference
stoichiometry: 2.0
species: 180728

180728
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Mesaconate_C5H4O4

192543
type: SpeciesReference
stoichiometry: 2.0
species: 180716

192519
type: SpeciesReference
stoichiometry: 2.0
species: 177459

177459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Itaconyl-CoA_C26H35N7O19P3S

192495
type: SpeciesReference
stoichiometry: 2.0
species: 177471

177471
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Itaconate_C5H4O4

192459
type: SpeciesReference
stoichiometry: 6.0
species: 168545

168545
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Coenzyme A_C21H32N7O16P3S

192579
type: SpeciesReference
stoichiometry: 3.0
species: 174154

192555
type: SpeciesReference
stoichiometry: 6.0
species: 183700

192531
type: SpeciesReference
stoichiometry: 2.0
species: 186138

186138
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Succinyl-CoA_C25H35N7O19P3S

192507
type: SpeciesReference
stoichiometry: 2.0
species: 186101

186101
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Succinate_C4H4O4

192483
type: SpeciesReference
stoichiometry: 3.0
species: 175458

192567
type: SpeciesReference
stoichiometry: 3.0
species: 165411

192471
type: SpeciesReference
stoichiometry: 3.0
species: 166928

947480
type: Reaction
modifier: 210007
modifier: 209970
reactant: 209910
reactant: 209884
reactant: 209897
modifier: 209958
is: http://identifiers.org/ec-code/6.2.1.3
reversible: false
modifier: 210019
modifier: 209995
notes: R_FACOAL150 subsystem: Fatty acid activation R_FACOAL150 equation: [c] : atp + coa + ptdca <==> amp + ppi + ptdcacoa R_FACOAL204i subsystem: Fatty acid activation R_FACOAL204i equation: [c] : arachd + atp + coa --> amp + arachdcoa + ppi R_FACOAL170 subsystem: Fatty acid activation R_FACOAL170 equation: [c] : atp + coa + hpdca <==> amp + hpdcacoa + ppi
fast: false
product: 209946
product: 209934
modifier: 210043
is: ENSMUSG00000031278.5
modifier: 209983
modifier: 210031
product: 209922

176373
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: heptadecanoate_C17H33O2

209910
type: SpeciesReference
stoichiometry: 1.0
species: 166904

209884
type: SpeciesReference
stoichiometry: 1.0
species: 168509

209897
type: SpeciesReference
stoichiometry: 1.0
species: 166616

166616
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: arachidonic acid_C20H31O2

176385
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: heptadecanoyl coa_C38H64N7O17P3S

209946
type: SpeciesReference
stoichiometry: 1.0
species: 183917

183917
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Diphosphate_HO7P2

209934
type: SpeciesReference
stoichiometry: 1.0
species: 166219

166219
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: AMP_C10H12N5O7P

184651
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: pentadecanoyl Coenzyme A_C36H60N7O17P3S

209922
type: SpeciesReference
stoichiometry: 1.0
species: 166652

166652
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: C20:4-CoA_C41H62N7O17P3S

163039
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: pentaglutamyl folate (DHF)_C39H43N11O18

183688
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Phosphate_HO4P

165617
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Adrenyl carnitine_C29H49NO4

167711
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: CDP diacylglycerol (homo sapiens)_C12H17N3O11P2FULLRCO2FULLR2CO2

164040
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: R total 2 carnitine_CO2FULLR2C7H14NO2

174649
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Glycine_C2H5NO2

179328
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Leukotriene C4_C30H45N3O9S

164691
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Acetone_C3H6O

185011
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Retinal_C20H28O

946362
type: Reaction
name: Leukotriene C4 synthase
is: ENSMUSG00000026688.3
is: ENSMUSG00000074604.2
is: ENSMUSG00000078650.1
reactant: 199232
reversible: false
fast: false
product: 199256
reactant: 199244
notes: R_LTC4Sr subsystem: Eicosanoid Metabolism R_LTC4Sr equation: [r] : gthrd + leuktrA4 --> leuktrC4

199232
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stoichiometry: 1.0
species: 179279

179279
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Leukotriene A4_C20H29O3

199256
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stoichiometry: 1.0
species: 179352

179352
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Leukotriene C4_C30H45N3O9S

199244
type: SpeciesReference
stoichiometry: 1.0
species: 175422

175422
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Reduced glutathione_C10H16N3O6S

183313
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2

165883
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: _2-Oxoglutarate_C5H4O5

952965
type: Reaction
product: 263415
is: http://identifiers.org/ec-code/2.1.1.13
fast: false
reversible: false
notes: R_METS subsystem: Methionine Metabolism R_METS equation: [c] : 5mthf + hcys-L --> h + met-L + thf
is: ENSMUSG00000021311.6
reactant: 263367
product: 263403
reactant: 263379
product: 263391
name: methionine synthase

263415
type: SpeciesReference
stoichiometry: 1.0
species: 175722

263367
type: SpeciesReference
stoichiometry: 1.0
species: 175926

175926
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Homocysteine_C4H9NO2S

263403
type: SpeciesReference
stoichiometry: 1.0
species: 180740

180740
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Methionine_C5H11NO2S

263379
type: SpeciesReference
stoichiometry: 1.0
species: 163281

163281
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-Methyltetrahydrofolate_C20H24N7O6

263391
type: SpeciesReference
stoichiometry: 1.0
species: 186792

955679
type: Reaction
is: http://identifiers.org/ec-code/3.1.3.3
reversible: false
product: 289953
fast: false
reactant: 289893
is: ENSMUSG00000028525.6
product: 289941
reactant: 289905
is: http://identifiers.org/ec-code/3.1.4.17
product: 289929
product: 289917
notes: R_PDE1 subsystem: Nucleotides R_PDE1 equation: [c] : camp + h2o --> amp + h R_PSP_L subsystem: Glycine, Serine, and Threonine Metabolism R_PSP_L equation: [c] : h2o + pser-L --> pi + ser-L
reactant: 289880

289953
type: SpeciesReference
stoichiometry: 1.0
species: 175722

289893
type: SpeciesReference
stoichiometry: 1.0
species: 184627

184627
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: O-Phospho-L-serine_C3H6NO6P

289941
type: SpeciesReference
stoichiometry: 1.0
species: 166219

289905
type: SpeciesReference
stoichiometry: 2.0
species: 175614

289929
type: SpeciesReference
stoichiometry: 1.0
species: 183652

289917
type: SpeciesReference
stoichiometry: 1.0
species: 185532

185532
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Serine_C3H7NO3

289880
type: SpeciesReference
stoichiometry: 1.0
species: 167495

167495
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: cAMP_C10H11N5O6P

954105
type: Reaction
product: 273970
notes: R_D_DASH_LACt2 subsystem: Transport, Extracellular R_D_DASH_LACt2 equation: h[e] + lac-D[e] <==> h[c] + lac-D[c] R_L_DASH_LACt2r subsystem: Transport, Extracellular R_L_DASH_LACt2r equation: h[e] + lac-L[e] <==> h[c] + lac-L[c]
reactant: 273910
reversible: true
product: 273946
reactant: 273934
fast: false
is: ENSMUSG00000032988.2
product: 273958
reactant: 273922

273970
type: SpeciesReference
stoichiometry: 2.0
species: 175722

273910
type: SpeciesReference
stoichiometry: 2.0
species: 175734

175734
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: H+_H

273946
type: SpeciesReference
stoichiometry: 1.0
species: 179086

273934
type: SpeciesReference
stoichiometry: 1.0
species: 179062

179062
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: D-Lactate_C3H5O3

273958
type: SpeciesReference
stoichiometry: 1.0
species: 179050

273922
type: SpeciesReference
stoichiometry: 1.0
species: 179098

179098
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Lactate_C3H5O3

951749
type: Reaction
product: 248954
is: http://identifiers.org/ec-code/1.4.3.4
reactant: 248689
product: 248834
product: 248978
is: http://identifiers.org/ec-code/1.2.1.5
reversible: false
product: 248906
product: 248858
product: 248930
is: ENSMUSG00000040147.5
reactant: 248750
product: 248882
reactant: 248641
product: 248810
reactant: 248762
reactant: 248605
reactant: 248593
product: 248798
reactant: 248738
reactant: 248774
is: http://identifiers.org/ec-code/1.4.3.6
product: 248822
product: 248846
reactant: 248617
product: 248966
reactant: 248653
reactant: 248629
reactant: 248665
reactant: 248702
product: 248870
reactant: 248677
reactant: 248714
product: 248942
reactant: 248726
product: 248894
notes: R_3MOXTYROX subsystem: Tyrosine metabolism R_3MOXTYROX equation: [c] : 3moxtyr + h2o + o2 --> 3mox4hpac + h2o2 + nh4 R_MAOLNOR subsystem: Tyrosine metabolism R_MAOLNOR equation: [c] : h2o + normete-L + o2 --> 3m4hpga + h2o2 + nh4 R_APRTO2 subsystem: Arginine and Proline Metabolism R_APRTO2 equation: [c] : aprut + h2o + o2 --> h2o2 + n4abutn + nh4 R_42A12BOOX subsystem: Tyrosine metabolism R_42A12BOOX equation: [c] : dopa + h2o + o2 --> 34dhpac + h2o2 + nh4 R_PEAMNO subsystem: Phenylalanine metabolism R_PEAMNO equation: [c] : h2o + o2 + peamn --> h2o2 + nh4 + pacald R_MACOXO subsystem: Histidine Metabolism R_MACOXO equation: [c] : 3mldz + h2o + nad --> 3mlda + (2) h + nadh R_3HXKYNOXDA subsystem: Tryptophan metabolism R_3HXKYNOXDA equation: [c] : 3hxkynam + o2 --> 48dhoxquin + h2o2 + nh4 R_41R2A1H12BOOX subsystem: Tyrosine metabolism R_41R2A1H12BOOX equation: [c] : h2o + nrpphr + o2 --> 34dhmald + h2o2 + nh4 R_TRYPTAOX subsystem: Tryptophan metabolism R_TRYPTAOX equation: [c] : h2o + o2 + trypta --> h2o2 + id3acald + nh4 R_5HXKYNOXDA subsystem: Tryptophan metabolism R_5HXKYNOXDA equation: [c] : 5hxkynam + o2 --> 46dhoxquin + h2o2 + nh4 R_TYROXDAc subsystem: Tyrosine metabolism R_TYROXDAc equation: [c] : h2o + o2 + tym --> 4hoxpacd + h2o2 + nh4 R_5HOXINOXDA subsystem: Tryptophan metabolism R_5HOXINOXDA equation: [c] : h2o + o2 + srtn --> 5hoxindact + h2o2 + nh4 R_41R1H2MAE12BOOX subsystem: Tyrosine metabolism R_41R1H2MAE12BOOX equation: [c] : adrnl + h2o + o2 --> 34dhmald + h2o2 + mma
product: 248918
product: 248786
fast: false

248954
type: SpeciesReference
stoichiometry: 2.0
species: 161551

248689
type: SpeciesReference
stoichiometry: 1.0
species: 183349

183349
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Phenethylamine_C8H12N

248834
type: SpeciesReference
stoichiometry: 11.0
species: 181752

248978
type: SpeciesReference
stoichiometry: 1.0
species: 181510

248906
type: SpeciesReference
stoichiometry: 12.0
species: 175542

175542
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Hydrogen peroxide_H2O2

248858
type: SpeciesReference
stoichiometry: 1.0
species: 162047

248930
type: SpeciesReference
stoichiometry: 1.0
species: 162410

162410
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4,8-Dihydroxyquinoline_C9H7NO2

248750
type: SpeciesReference
stoichiometry: 11.0
species: 175614

248882
type: SpeciesReference
stoichiometry: 1.0
species: 163136

163136
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-Hydroxyindoleacetaldehyde_C10H9NO2

248641
type: SpeciesReference
stoichiometry: 1.0
species: 165629

165629
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Adrenaline_C9H14NO3

248810
type: SpeciesReference
stoichiometry: 1.0
species: 162592

248762
type: SpeciesReference
stoichiometry: 12.0
species: 182154

248605
type: SpeciesReference
stoichiometry: 1.0
species: 162059

248593
type: SpeciesReference
stoichiometry: 1.0
species: 182008

248798
type: SpeciesReference
stoichiometry: 1.0
species: 181340

181340
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N4-Acetylaminobutanal_C6H11NO2

248738
type: SpeciesReference
stoichiometry: 1.0
species: 171451

248774
type: SpeciesReference
stoichiometry: 1.0
species: 166495

248822
type: SpeciesReference
stoichiometry: 1.0
species: 161587

248846
type: SpeciesReference
stoichiometry: 1.0
species: 181078

181078
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Methylamine_C1H6N

248617
type: SpeciesReference
stoichiometry: 1.0
species: 181984

181984
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Normetanephrine_C9H14NO3

248966
type: SpeciesReference
stoichiometry: 1.0
species: 162398

162398
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4,6-Dihydroxyquinoline_C9H7NO2

248653
type: SpeciesReference
stoichiometry: 1.0
species: 187308

187308
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Tryptamine_C10H13N2

248629
type: SpeciesReference
stoichiometry: 1.0
species: 181437

248665
type: SpeciesReference
stoichiometry: 1.0
species: 187500

187500
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Tyramine_C8H12NO

248702
type: SpeciesReference
stoichiometry: 1.0
species: 163233

163233
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-Hydroxykynurenamine_C9H13N2O2

248870
type: SpeciesReference
stoichiometry: 1.0
species: 162011

248677
type: SpeciesReference
stoichiometry: 1.0
species: 162144

162144
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Methoxytyramine_C9H14NO2

248714
type: SpeciesReference
stoichiometry: 1.0
species: 185897

185897
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Serotonin_C10H13N2O

248942
type: SpeciesReference
stoichiometry: 2.0
species: 175722

248726
type: SpeciesReference
stoichiometry: 1.0
species: 161987

161987
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Hydroxykynurenamine_C9H13N2O2

248894
type: SpeciesReference
stoichiometry: 1.0
species: 182827

248918
type: SpeciesReference
stoichiometry: 1.0
species: 177119

177119
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Indole-3-acetaldehyde_C10H9NO

248786
type: SpeciesReference
stoichiometry: 1.0
species: 162132

177205
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: IDP_C10H11N4O11P2

169865
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: dADP_C10H12N5O9P2

169792
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Cytidine_C9H13N3O5

950054
type: Reaction
product: 233346
is: ENSMUSG00000033774.3
reactant: 233261
reactant: 233249
product: 233310
is: http://identifiers.org/ec-code/1.5.1.5
product: 233298
is: http://identifiers.org/ec-code/3.5.4.9
fast: false
is: http://identifiers.org/ec-code/6.3.4.3
reactant: 233274
reactant: 233213
reactant: 233201
reversible: true
product: 233334
product: 233322
notes: R_MTHFD subsystem: Folate Metabolism R_MTHFD equation: [c] : mlthf + nadp <==> methf + nadph R_FTHFL subsystem: Folate Metabolism R_FTHFL equation: [c] : atp + for + thf <==> 10fthf + adp + pi R_MTHFC subsystem: Folate Metabolism R_MTHFC equation: [c] : h2o + methf <==> 10fthf + h
reactant: 233237
reactant: 233225
product: 233286

233346
type: SpeciesReference
stoichiometry: 1.0
species: 181631

233261
type: SpeciesReference
stoichiometry: 1.0
species: 181558

233249
type: SpeciesReference
stoichiometry: 1.0
species: 180764

180764
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5,10-Methenyltetrahydrofolate_C20H20N7O6

233310
type: SpeciesReference
stoichiometry: 1.0
species: 165387

233298
type: SpeciesReference
stoichiometry: 1.0
species: 180764

233274
type: SpeciesReference
stoichiometry: 1.0
species: 175614

233213
type: SpeciesReference
stoichiometry: 1.0
species: 181054

181054
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5,10-Methylenetetrahydrofolate_C20H21N7O6

233201
type: SpeciesReference
stoichiometry: 1.0
species: 172788

172788
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Formate_CH1O2

233334
type: SpeciesReference
stoichiometry: 2.0
species: 160758

233322
type: SpeciesReference
stoichiometry: 1.0
species: 175722

233237
type: SpeciesReference
stoichiometry: 1.0
species: 166904

233225
type: SpeciesReference
stoichiometry: 1.0
species: 186792

233286
type: SpeciesReference
stoichiometry: 1.0
species: 183652

946290
type: Reaction
is: http://identifiers.org/ec-code/2.2.1.1
fast: false
reactant: 198597
product: 198649
reactant: 198584
product: 198636
reversible: true
is: ENSMUSG00000025519.2
notes: R_TKT2 subsystem: Pentose Phosphate Pathway R_TKT2 equation: [c] : e4p + xu5p-D <==> f6p + g3p R_TKT1 subsystem: Pentose Phosphate Pathway R_TKT1 equation: [c] : r5p + xu5p-D <==> g3p + s7p
is: ENSMUSG00000021957.5
reactant: 198610
product: 198623
is: ENSMUSG00000031397.4

198597
type: SpeciesReference
stoichiometry: 1.0
species: 184939

184939
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: alpha-D-Ribose 5-phosphate_C5H9O8P

198649
type: SpeciesReference
stoichiometry: 1.0
species: 185265

185265
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Sedoheptulose 7-phosphate_C7H13O10P

198584
type: SpeciesReference
stoichiometry: 1.0
species: 171896

171896
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Erythrose 4-phosphate_C4H7O7P

198636
type: SpeciesReference
stoichiometry: 1.0
species: 172475

172475
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Fructose 6-phosphate_C6H11O9P

198610
type: SpeciesReference
stoichiometry: 2.0
species: 188706

188706
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Xylulose 5-phosphate_C5H9O8P

198623
type: SpeciesReference
stoichiometry: 2.0
species: 173461

173461
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Glyceraldehyde 3-phosphate_C3H5O6P

165509
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: ADPribose_C15H21N5O14P2

179895
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: alpha-D-mannosyl-beta-D-mannosyl-diacylchitobiosyldiphosphodolichol, human liver homolog_C1360H2228N20O270P20

167603
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Cob(II)alamin_C62H92CoN13O14P

954273
type: Reaction
reactant: 275346
reactant: 275370
product: 275394
fast: false
product: 275382
reactant: 275358
product: 275418
reversible: false
notes: R_CAMPt subsystem: Transport, Extracellular R_CAMPt equation: atp[c] + camp[c] + h2o[c] --> adp[c] + camp[e] + h[c] + pi[c] R_CGMPt subsystem: Transport, Extracellular R_CGMPt equation: _35cgmp[c] + atp[c] + h2o[c] --> 35cgmp[e] + adp[c] + h[c] + pi[c]
product: 275406
reactant: 275334
product: 275430
is: ENSMUSG00000022822.7
is: ENSMUSG00000079736.1

275346
type: SpeciesReference
stoichiometry: 2.0
species: 166904

275370
type: SpeciesReference
stoichiometry: 2.0
species: 175614

275394
type: SpeciesReference
stoichiometry: 1.0
species: 167507

167507
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: cAMP_C10H11N5O6P

275382
type: SpeciesReference
stoichiometry: 2.0
species: 183652

275358
type: SpeciesReference
stoichiometry: 1.0
species: 161660

275418
type: SpeciesReference
stoichiometry: 2.0
species: 175722

275406
type: SpeciesReference
stoichiometry: 2.0
species: 165387

275334
type: SpeciesReference
stoichiometry: 1.0
species: 167495

275430
type: SpeciesReference
stoichiometry: 1.0
species: 161673

161673
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: _3',5'-Cyclic GMP_C10H11N5O7P

948406
type: Reaction
is: ENSMUSG00000021054.3
product: 217363
notes: R_SBPP1er subsystem: Sphingolipid Metabolism R_SBPP1er equation: [r] : h2o + sph1p --> pi + sphgn R_SBPP3er subsystem: Sphingolipid Metabolism R_SBPP3er equation: [r] : h2o + sphs1p --> pi + sphings
reactant: 217327
product: 217375
reversible: false
reactant: 217351
reactant: 217339
fast: false
product: 217387

217363
type: SpeciesReference
stoichiometry: 2.0
species: 183724

183724
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Phosphate_HO4P

217327
type: SpeciesReference
stoichiometry: 1.0
species: 185849

185849
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Sphingosine 1-phosphate_C18H37NO5P

217375
type: SpeciesReference
stoichiometry: 1.0
species: 185789

185789
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Sphingosine_C18H38NO2

217351
type: SpeciesReference
stoichiometry: 2.0
species: 175686

217339
type: SpeciesReference
stoichiometry: 1.0
species: 185729

185729
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Sphinganine 1-phosphate_C18H39NO5P

217387
type: SpeciesReference
stoichiometry: 1.0
species: 185753

185753
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Sphinganine_C18H40NO2

174540
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO

170955
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Digalactosylceramide_C30H56NO12FULLRCO

187223
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Trehalose_C12H22O11

171884
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-erythro-4-Hydroxyglutamate_C5H8NO5

168473
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: CO2_CO2

165172
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (Gal)3 (Glc)1 (GlcNAc)1 (Cer)1_C55H95N3O30FULLRCO

184915
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Quinolinate_C7H3NO4

167133
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Bilirubin monoglucuronide_C39H44N4O12

185945
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S

166027
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Alanine_C3H7NO2

176746
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 9_C61H87N3O76S8

172101
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: phosphoethanolaminyl-trimannosyl-glucosaminyl-acylphosphatidylinositol (H6')_C51H94N2O32P2FULLRCO2FULLR2CO2

178617
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate II (core 2-linked), degradation product 6_C44H72N4O33SX

161745
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: _3'-AMP_C10H12N5O7P

162023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3-Methylbut-2-enoyl-CoA_C26H38N7O17P3S

167687
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: CDPcholine_C14H25N4O11P2

951859
type: Reaction
product: 249558
reactant: 249546
reversible: true
product: 249570
notes: R_PROSTGF2t subsystem: Transport, Extracellular R_PROSTGF2t equation: prostgf2[e] <==> prostgf2[c] R_SRTNtu subsystem: Transport, Extracellular R_SRTNtu equation: srtn[e] <==> srtn[c] R_PROSTGE2t2 subsystem: Transport, Extracellular R_PROSTGE2t2 equation: prostge2[e] <==> prostge2[c]
fast: false
is: ENSMUSG00000023829.7
reactant: 249534
product: 249582
reactant: 249522

249558
type: SpeciesReference
stoichiometry: 1.0
species: 184459

184459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Prostaglandin E2_C20H31O5

249546
type: SpeciesReference
stoichiometry: 1.0
species: 184507

184507
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Prostaglandin F2alpha_C20H33O5

249570
type: SpeciesReference
stoichiometry: 1.0
species: 184495

184495
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Prostaglandin F2alpha_C20H33O5

249534
type: SpeciesReference
stoichiometry: 1.0
species: 184471

184471
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Prostaglandin E2_C20H31O5

249582
type: SpeciesReference
stoichiometry: 1.0
species: 185897

249522
type: SpeciesReference
stoichiometry: 1.0
species: 185909

185909
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Serotonin_C10H13N2O

165471
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: ADPmannose_C16H23N5O15P2

187657
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: UDP_C9H11N2O12P2

171196
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Dimethylallyl diphosphate_C5H9O7P2

160992
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _17alpha-Hydroxypregnenolone_C21H32O3

956113
type: Reaction
fast: false
product: 293500
is: http://identifiers.org/ec-code/1.13.11.20
name: cysteine oxidase
reactant: 293476
product: 293488
is: ENSMUSG00000042750.6
reactant: 293464
reversible: false
notes: R_CYSO subsystem: Taurine and hypotaurine metabolism R_CYSO equation: [c] : cys-L + o2 --> 3sala + (2) h

293500
type: SpeciesReference
stoichiometry: 2.0
species: 175722

293476
type: SpeciesReference
stoichiometry: 1.0
species: 182154

293488
type: SpeciesReference
stoichiometry: 1.0
species: 162266

162266
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Sulfino-L-alanine_C3H5NO4S

293464
type: SpeciesReference
stoichiometry: 1.0
species: 169680

177651
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 16_C160H258N11O137S7

174853
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]})_C66H111O56X

948887
type: Reaction
product: 221198
is: http://identifiers.org/ec-code/1.5.3.1
reactant: 221150
reversible: false
reactant: 221174
fast: false
reactant: 221162
product: 221210
notes: R_LPCOXp subsystem: Lysine Metabolism R_LPCOXp equation: [x] : Lpipecol + o2 --> h + h2o2 + thp2c R_SARCOXp subsystem: Glycine, Serine, and Threonine Metabolism R_SARCOXp equation: [x] : h2o + o2 + sarcs --> fald + gly + h2o2
product: 221222
is: http://identifiers.org/ec-code/1.5.3.7
is: ENSMUSG00000017453.3
product: 221234
product: 221186
reactant: 221138

221198
type: SpeciesReference
stoichiometry: 1.0
species: 186924

186924
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: _2,3,4,5-Tetrahydropyridine-2-carboxylate_C6H8NO2

221150
type: SpeciesReference
stoichiometry: 2.0
species: 182214

182214
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: O2_O2

221174
type: SpeciesReference
stoichiometry: 1.0
species: 185337

185337
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Sarcosine_C3H7NO2

221162
type: SpeciesReference
stoichiometry: 1.0
species: 163847

163847
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: L-Pipecolate_C6H11NO2

221210
type: SpeciesReference
stoichiometry: 2.0
species: 175602

175602
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Hydrogen peroxide_H2O2

221222
type: SpeciesReference
stoichiometry: 1.0
species: 174673

174673
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Glycine_C2H5NO2

221234
type: SpeciesReference
stoichiometry: 1.0
species: 175806

221186
type: SpeciesReference
stoichiometry: 1.0
species: 172620

172620
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Formaldehyde_CH2O

221138
type: SpeciesReference
stoichiometry: 1.0
species: 175698

175698
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: H2O_H2O

946590
type: Reaction
fast: false
reactant: 201552
is: ENSMUSG00000000628.3
reversible: false
is: ENSMUSG00000041798.7
is: http://identifiers.org/ec-code/2.7.1.1
reactant: 201528
is: ENSMUSG00000025877.7
product: 201613
reactant: 201540
product: 201637
product: 201601
product: 201589
reactant: 201577
product: 201625
is: ENSMUSG00000037012.8
is: http://identifiers.org/ec-code/2.7.1.7
reactant: 201565
notes: R_HEX10 subsystem: Aminosugar Metabolism R_HEX10 equation: [c] : atp + gam --> adp + gam6p + h R_HEX4 subsystem: Fructose and Mannose Metabolism R_HEX4 equation: [c] : atp + man --> adp + h + man6p R_HEX7 subsystem: Fructose and Mannose Metabolism R_HEX7 equation: [c] : atp + fru --> adp + f6p + h R_HEX1 subsystem: Glycolysis/Gluconeogenesis R_HEX1 equation: [c] : atp + glc-D --> adp + g6p + h
product: 201649
is: ENSMUSG00000020080.7

201552
type: SpeciesReference
stoichiometry: 1.0
species: 172932

172932
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Fructose_C6H12O6

201528
type: SpeciesReference
stoichiometry: 4.0
species: 166904

201613
type: SpeciesReference
stoichiometry: 4.0
species: 165387

201540
type: SpeciesReference
stoichiometry: 1.0
species: 180512

180512
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Mannose_C6H12O6

201637
type: SpeciesReference
stoichiometry: 1.0
species: 180500

201601
type: SpeciesReference
stoichiometry: 1.0
species: 173485

173485
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Glucose 6-phosphate_C6H11O9P

201589
type: SpeciesReference
stoichiometry: 1.0
species: 173875

173875
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Glucosamine 6-phosphate_C6H13NO8P

201577
type: SpeciesReference
stoichiometry: 1.0
species: 174274

174274
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Glucose_C6H12O6

201625
type: SpeciesReference
stoichiometry: 1.0
species: 172475

201565
type: SpeciesReference
stoichiometry: 1.0
species: 173887

173887
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Glucosamine_C6H14NO5

201649
type: SpeciesReference
stoichiometry: 4.0
species: 175722

946047
type: Reaction
reversible: false
name: Sphingomyelin synthase (homo sapiens)
product: 196684
product: 196672
reactant: 196648
notes: R_SMS subsystem: Sphingolipid Metabolism R_SMS equation: [c] : crm_hs + pchol_hs --> dag_hs + sphmyln_hs
is: ENSMUSG00000040451.7
fast: false
reactant: 196660

196684
type: SpeciesReference
stoichiometry: 1.0
species: 185801

185801
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO

196672
type: SpeciesReference
stoichiometry: 1.0
species: 169878

169878
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2

196648
type: SpeciesReference
stoichiometry: 1.0
species: 168738

168738
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

196660
type: SpeciesReference
stoichiometry: 1.0
species: 183155

183155
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

165064
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: sialyl (2,3) sialyl (2,6) galactosylgloboside (homo sapiens)_C72H121N4O43FULLRCO

166880
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Aspartate_C4H6NO4

184807
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Perillyl aldehyde_C10H14O

179666
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: alpha-Linolenoyl-CoA_C39H60N7O17P3S

952351
type: Reaction
fast: false
product: 255345
is: http://identifiers.org/ec-code/2.7.4.2
reactant: 255321
notes: R_PMEVKx subsystem: Cholesterol Metabolism R_PMEVKx equation: [x] : 5pmev + atp --> 5dpmev + adp
product: 255333
is: ENSMUSG00000027952.6
reversible: false
name: phosphomevalonate kinase
reactant: 255308

255345
type: SpeciesReference
stoichiometry: 1.0
species: 165447

165447
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: ADP_C10H12N5O10P2

255321
type: SpeciesReference
stoichiometry: 1.0
species: 163317

163317
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: (R)-5-Phosphomevalonate_C6H10O7P

255333
type: SpeciesReference
stoichiometry: 1.0
species: 163064

163064
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: (R)-5-Diphosphomevalonate_C6H10O10P2

255308
type: SpeciesReference
stoichiometry: 1.0
species: 166964

166964
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: ATP_C10H12N5O13P3

185837
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Sphingosine 1-phosphate_C18H37NO5P

188598
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _7-alpha,25-Dihydroxycholesterol_C27H46O3

948250
type: Reaction
notes: R_CEPTE subsystem: Glycerophospholipid Metabolism R_CEPTE equation: [c] : cdpea + dag_hs --> cmp + h + pe_hs R_CEPTC subsystem: Glycerophospholipid Metabolism R_CEPTC equation: [c] : cdpchol + dag_hs --> cmp + h + pchol_hs
reactant: 216207
reactant: 216195
product: 216243
is: ENSMUSG00000040774.7
fast: false
reversible: false
product: 216267
product: 216255
product: 216231
reactant: 216219

216207
type: SpeciesReference
stoichiometry: 1.0
species: 167687

216195
type: SpeciesReference
stoichiometry: 2.0
species: 169878

216243
type: SpeciesReference
stoichiometry: 1.0
species: 183155

216267
type: SpeciesReference
stoichiometry: 2.0
species: 175722

216255
type: SpeciesReference
stoichiometry: 1.0
species: 183301

183301
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2

216231
type: SpeciesReference
stoichiometry: 2.0
species: 168316

216219
type: SpeciesReference
stoichiometry: 1.0
species: 167723

167723
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: CDPethanolamine_C11H19N4O11P2

183071
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: phosphatidylinositol (homo sapiens)_C9H16O9PFULLRCO2FULLR2CO2

948358
type: Reaction
is: ENSMUSG00000075551.2
is: ENSMUSG00000054417.5
is: ENSMUSG00000029630.7
is: ENSMUSG00000056035.6
product: 216954
reactant: 216942
is: ENSMUSG00000029727.6
reactant: 216906
product: 216966
name: cytochrome p450 P450 3A7
is: ENSMUSG00000075552.2
reactant: 216930
fast: false
product: 216978
reversible: false
notes: R_P4503A7r subsystem: Steroid Metabolism R_P4503A7r equation: [r] : h + nadph + o2 + tststerone --> 6htststerone + h2o + nadp
is: ENSMUSG00000061292.5
reactant: 216918
is: ENSMUSG00000038656.4
is: ENSMUSG00000070419.3

216954
type: SpeciesReference
stoichiometry: 1.0
species: 175686

216942
type: SpeciesReference
stoichiometry: 1.0
species: 175794

216906
type: SpeciesReference
stoichiometry: 1.0
species: 182202

182202
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: O2_O2

216966
type: SpeciesReference
stoichiometry: 1.0
species: 181607

181607
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

216930
type: SpeciesReference
stoichiometry: 1.0
species: 187332

187332
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Testosterone_C19H28O2

216978
type: SpeciesReference
stoichiometry: 1.0
species: 163438

163438
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _6 beta hydroxy testosterone_C19H28O3

216918
type: SpeciesReference
stoichiometry: 1.0
species: 181667

181667
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

178172
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 14_C143H230N10O114S4X

166784
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Ascorbate_C6H8O6

953649
type: Reaction
product: 268594
is: ENSMUSG00000006731.7
product: 268582
product: 268606
is: http://identifiers.org/ec-code/2.4.1.92
product: 268546
notes: R_GALGT3 subsystem: Sphingolipid Metabolism R_GALGT3 equation: [g] : gd3_hs + udpacgal --> gd2_hs + h + udp R_GALGT2 subsystem: Sphingolipid Metabolism R_GALGT2 equation: [g] : gm3_hs + udpacgal --> gm2_hs + h + udp R_GALGT4 subsystem: Sphingolipid Metabolism R_GALGT4 equation: [g] : gt3_hs + udpacgal --> gt2_hs + h + udp R_GALGT1 subsystem: Sphingolipid Metabolism R_GALGT1 equation: [g] : galgluside_hs + udpacgal --> ga2_hs + h + udp
product: 268558
reactant: 268534
reversible: false
reactant: 268486
reactant: 268510
product: 268570
reactant: 268498
reactant: 268522
fast: false

268594
type: SpeciesReference
stoichiometry: 1.0
species: 175313

175313
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GT2 (homo sapiens)_C71H117N5O41FULLRCO

268582
type: SpeciesReference
stoichiometry: 1.0
species: 173521

173521
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GA2 (homo sapiens)_C38H69N2O17FULLRCO

268606
type: SpeciesReference
stoichiometry: 1.0
species: 174950

174950
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: ganglioside GM2 (homo sapiens)_C49H85N3O25FULLRCO

268546
type: SpeciesReference
stoichiometry: 1.0
species: 174070

174070
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GD2 (homo sapiens)_C60H101N4O33FULLRCO

268558
type: SpeciesReference
stoichiometry: 4.0
species: 187608

268534
type: SpeciesReference
stoichiometry: 1.0
species: 174094

174094
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GD3 (homo sapiens)_C52H88N3O28FULLRCO

268486
type: SpeciesReference
stoichiometry: 1.0
species: 175337

175337
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GT3 (homo sapiens)_C63H104N4O36FULLRCO

268510
type: SpeciesReference
stoichiometry: 4.0
species: 187681

187681
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550

268570
type: SpeciesReference
stoichiometry: 4.0
species: 175746

268498
type: SpeciesReference
stoichiometry: 1.0
species: 173802

268522
type: SpeciesReference
stoichiometry: 1.0
species: 174974

174974
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: ganglioside GM3 (homo sapiens)_C41H72N2O20FULLRCO

179425
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: lignocericyl coenzyme A_C45H78N7O17P3S

169577
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate C (GalNAc6S-GlcA) proteoglycan_C45H66N2O45S3X

168799
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Carnitine_C7H15NO3

166351
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: androsterone glucuronide_C25H38O8

164028
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: R total 2 carnitine_CO2FULLR2C7H14NO2

173533
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514

174745
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: (R)-Glycerate_C3H5O4

187428
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: tetracosanoyl-CoA (n-C24:0CoA)_C45H78N7O17P3S

163269
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-Methylthioadenosine_C11H15N5O3S

165847
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: _1-alkyl 2-lysoglycerol 3-phosphocholine_C10H21O5NPFULLR

949488
type: Reaction
reversible: true
notes: R_PMANM subsystem: Fructose and Mannose Metabolism R_PMANM equation: [c] : man1p <==> man6p R_PGMT subsystem: Glycolysis/Gluconeogenesis R_PGMT equation: [c] : g1p <==> g6p
is: ENSMUSG00000029171.7
product: 227410
fast: false
reactant: 227398
is: http://identifiers.org/ec-code/5.4.2.2
is: http://identifiers.org/ec-code/5.4.2.8
reactant: 227386
product: 227422

227410
type: SpeciesReference
stoichiometry: 1.0
species: 173485

227398
type: SpeciesReference
stoichiometry: 1.0
species: 180487

180487
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Mannose 1-phosphate_C6H11O9P

227386
type: SpeciesReference
stoichiometry: 1.0
species: 173377

173377
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Glucose 1-phosphate_C6H11O9P

227422
type: SpeciesReference
stoichiometry: 1.0
species: 180500

945781
type: Reaction
fast: false
name: alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
product: 194515
reversible: false
reactant: 194479
product: 194491
is: http://identifiers.org/ec-code/2.4.1.143
is: ENSMUSG00000053460.6
reactant: 194467
product: 194503
notes: R_M16NTg subsystem: N-Glycan Biosynthesis R_M16NTg equation: [g] : nm2masn + uacgam --> h + n2m2masn + udp

194515
type: SpeciesReference
stoichiometry: 1.0
species: 175746

194479
type: SpeciesReference
stoichiometry: 1.0
species: 187572

194491
type: SpeciesReference
stoichiometry: 1.0
species: 181223

181223
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: ((N-acetyl-D-glucosaminyl)2-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C50H83N4O35X

194467
type: SpeciesReference
stoichiometry: 1.0
species: 181885

181885
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C42H70N3O30X

194503
type: SpeciesReference
stoichiometry: 1.0
species: 187608

945429
type: Reaction
reversible: false
product: 191267
product: 191255
reactant: 191231
is: ENSMUSG00000063953.1
notes: R_ADMDC subsystem: Arginine and Proline Metabolism R_ADMDC equation: [c] : amet + h --> ametam + co2
reactant: 191243
is: ENSMUSG00000075232.2
name: adenosylmethionine decarboxylase
fast: false
is: http://identifiers.org/ec-code/4.1.1.50
is: ENSMUSG00000060096.2

191267
type: SpeciesReference
stoichiometry: 1.0
species: 166207

166207
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: S-Adenosylmethioninamine_C14H24N6O3S

191255
type: SpeciesReference
stoichiometry: 1.0
species: 168436

168436
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: CO2_CO2

191231
type: SpeciesReference
stoichiometry: 1.0
species: 166159

166159
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: S-Adenosyl-L-methionine_C15H23N6O5S

191243
type: SpeciesReference
stoichiometry: 1.0
species: 175722

953577
type: Reaction
name: urocanase
is: ENSMUSG00000034456.8
notes: R_URCN subsystem: Histidine Metabolism R_URCN equation: [c] : h2o + urcan --> 4izp
product: 268086
fast: false
is: http://identifiers.org/ec-code/4.2.1.49
reactant: 268074
reactant: 268062
reversible: false

268086
type: SpeciesReference
stoichiometry: 1.0
species: 162640

162640
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-Imidazolone-5-propanoate_C6H7N2O3

268074
type: SpeciesReference
stoichiometry: 1.0
species: 175614

268062
type: SpeciesReference
stoichiometry: 1.0
species: 187984

187984
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Urocanate_C6H5N2O2

164150
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: R total_CO2FULLR

184783
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Pyridoxine_C8H11NO3

949933
type: Reaction
reactant: 230923
modifier: 231153
reactant: 230875
product: 230995
reactant: 230947
reversible: false
reactant: 230899
reactant: 230959
product: 231044
reactant: 230851
is: http://identifiers.org/ec-code/4.2.1.18
fast: false
modifier: 231177
is: http://identifiers.org/ec-code/1.4.3.6
reactant: 230935
modifier: 231165
reactant: 230887
product: 231092
product: 231032
product: 231105
is: http://identifiers.org/ec-code/4.2.1.17
product: 231019
modifier: 231189
product: 231056
reactant: 230839
product: 231129
product: 231068
notes: R_C2M26DCOAHLm subsystem: Limonene and pinene degradation R_C2M26DCOAHLm equation: [m] : c2m26dcoa + h2o <==> 3h26dm5coa R_PTRCOX1 subsystem: Arginine and Proline Metabolism R_PTRCOX1 equation: [c] : h2o + o2 + ptrc --> 4abutn + h2o2 + nh4 R_42A12BOOX subsystem: Tyrosine metabolism R_42A12BOOX equation: [c] : dopa + h2o + o2 --> 34dhpac + h2o2 + nh4 R_T2M26DCOAHLm subsystem: Limonene and pinene degradation R_T2M26DCOAHLm equation: [m] : h2o + t2m26dcoa <==> 3h26dm5coa R_NMPTRCOX subsystem: Alkaloid biosynthesis II R_NMPTRCOX equation: [c] : nmptrc + o2 --> 1mpyr + h2o2 + nh4 R_MHISOR subsystem: Histidine Metabolism R_MHISOR equation: [c] : h2o + mhista + o2 --> 3mldz + h2o2 + nh4 R_PEAMNO subsystem: Phenylalanine metabolism R_PEAMNO equation: [c] : h2o + o2 + peamn --> h2o2 + nh4 + pacald R_TRYPTAOX subsystem: Tryptophan metabolism R_TRYPTAOX equation: [c] : h2o + o2 + trypta --> h2o2 + id3acald + nh4 R_HISTASE subsystem: Histidine Metabolism R_HISTASE equation: [c] : h2o + hista + o2 --> h2o2 + im4act + nh4 R_PRPNCOAHYDm subsystem: beta-Alanine metabolism R_PRPNCOAHYDm equation: [m] : h2o + prpncoa --> 3hpcoa R_MAOX subsystem: Tyrosine metabolism R_MAOX equation: [c] : h2o + mma + o2 --> fald + h2o2 + nh4 R_ECOAH1m subsystem: Tryptophan metabolism R_ECOAH1m equation: [m] : 3hbcoa <==> b2coa + h2o R_MGCHrm subsystem: Valine, Leucine, and Isoleucine Metabolism R_MGCHrm equation: [m] : 3mgcoa + h2o <==> hmgcoa R_13DAMPPOX subsystem: beta-Alanine metabolism R_13DAMPPOX equation: [c] : 13dampp + h2o + o2 --> bamppald + h2o2 + nh4
reactant: 230983
modifier: 231201
is: ENSMUSG00000078651.1
reactant: 230911
reactant: 230863
modifier: 231141
product: 231007
reactant: 230971
product: 231117
is: http://identifiers.org/ec-code/1.4.3.4
modifier: 231225
product: 231080
modifier: 231213

230923
type: SpeciesReference
stoichiometry: 1.0
species: 176241

176241
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Histamine_C5H10N3

161855
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574

230875
type: SpeciesReference
stoichiometry: 1.0
species: 187308

230995
type: SpeciesReference
stoichiometry: 1.0
species: 162059

230947
type: SpeciesReference
stoichiometry: 8.0
species: 175614

230899
type: SpeciesReference
stoichiometry: 1.0
species: 183349

230959
type: SpeciesReference
stoichiometry: 1.0
species: 184699

184699
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Putrescine_C4H14N2

231044
type: SpeciesReference
stoichiometry: 1.0
species: 161587

230851
type: SpeciesReference
stoichiometry: 1.0
species: 184555

184555
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Propenoyl-CoA_C24H34N7O17P3S

186174
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574

230935
type: SpeciesReference
stoichiometry: 1.0
species: 171451

230887
type: SpeciesReference
stoichiometry: 1.0
species: 181078

231092
type: SpeciesReference
stoichiometry: 9.0
species: 175542

231032
type: SpeciesReference
stoichiometry: 1.0
species: 161100

161100
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1-Methylpyrrolinium_C5H10N

231105
type: SpeciesReference
stoichiometry: 1.0
species: 161927

161927
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3-Hydroxypropionyl-CoA_C24H36N7O18P3S

231019
type: SpeciesReference
stoichiometry: 1.0
species: 177277

177277
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Imidazole-4-acetaldehyde_C5H6N2O

166976
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Crotonoyl-CoA_C25H36N7O17P3S

231056
type: SpeciesReference
stoichiometry: 1.0
species: 167001

167001
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: beta-Aminopropion aldehyde_C3H8NO

230839
type: SpeciesReference
stoichiometry: 1.0
species: 175662

231129
type: SpeciesReference
stoichiometry: 1.0
species: 172584

172584
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Formaldehyde_CH2O

231068
type: SpeciesReference
stoichiometry: 9.0
species: 181752

230983
type: SpeciesReference
stoichiometry: 9.0
species: 182154

162035
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3-Methylglutaconyl-CoA_C27H37N7O19P3S

230911
type: SpeciesReference
stoichiometry: 1.0
species: 181946

181946
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Methylputrescine_C5H16N2

230863
type: SpeciesReference
stoichiometry: 1.0
species: 180824

161806
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574

231007
type: SpeciesReference
stoichiometry: 1.0
species: 162496

162496
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-Aminobutanal_C4H10NO

230971
type: SpeciesReference
stoichiometry: 1.0
species: 160956

160956
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1,3-Diaminopropane_C3H12N2

231117
type: SpeciesReference
stoichiometry: 1.0
species: 177119

167435
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574

231080
type: SpeciesReference
stoichiometry: 1.0
species: 182827

176289
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574

947168
type: Reaction
reactant: 206993
name: alpha,alpha-trehalase
is: ENSMUSG00000032098.6
product: 207017
reversible: false
notes: R_TREHe subsystem: Starch and Sucrose Metabolism R_TREHe equation: [e] : h2o + tre --> (2) glc-D
reactant: 207005
is: http://identifiers.org/ec-code/3.2.1.28
fast: false

206993
type: SpeciesReference
stoichiometry: 1.0
species: 187235

187235
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Trehalose_C12H22O11

207017
type: SpeciesReference
stoichiometry: 2.0
species: 174286

174286
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: D-Glucose_C6H12O6

207005
type: SpeciesReference
stoichiometry: 1.0
species: 175626

175626
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: H2O_H2O

949355
type: Reaction
product: 226478
product: 226539
is: http://identifiers.org/ec-code/2.3.1.16
product: 226454
is: ENSMUSG00000038060.7
product: 226551
product: 226405
reactant: 226151
product: 226490
product: 226429
reactant: 226236
product: 226357
product: 226393
product: 226320
reactant: 226224
reactant: 226248
reactant: 226126
product: 226515
reactant: 226114
is: http://identifiers.org/ec-code/1.3.99.3
product: 226332
product: 226308
reactant: 226029
reactant: 226272
reactant: 226199
reactant: 226187
product: 226563
product: 226417
reactant: 226065
product: 226369
reactant: 226089
reactant: 226260
reactant: 226053
fast: false
product: 226466
reactant: 226101
reactant: 226077
product: 226527
reactant: 226175
reactant: 225993
reactant: 226211
reactant: 226163
product: 226344
reactant: 226041
reactant: 226139
product: 226502
product: 226381
notes: R_FAOXC2251836x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2251836x equation: [x] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_FAOXC180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC180x equation: [x] : coa + h2o + nad + o2 + stcoa --> accoa + h + h2o2 + nadh + pmtcoa R_FAOXC241181x subsystem: Fatty acid oxidation, peroxisome R_FAOXC241181x equation: [x] : (3) coa + (3) h2o + (3) nad + nrvnccoa + (3) o2 --> (3) accoa + (3) h + (3) h2o2 + (3) nadh + odecoa R_PEROXx subsystem: Fatty acid oxidation, peroxisome R_PEROXx equation: [x] : (3) coa + (3) h2o + (3) nad + (2) o2 + pristcoa --> accoa + dmnoncoa + (3) h + (2) h2o2 + (3) nadh + (2) ppcoa R_FAOXC2452253x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2452253x equation: [x] : coa + h2o + nad + o2 + tetpent3coa --> accoa + clpndcoa + h + h2o2 + nadh R_FAOXC2252053x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2252053x equation: [x] : coa + dcsptn1coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + tmndnccoa R_FAOXC183806x subsystem: Fatty acid oxidation, peroxisome R_FAOXC183806x equation: [x] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC200180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC200180x equation: [x] : arachcoa + coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + stcoa R_ACACT7p subsystem: Fatty Acid Metabolism R_ACACT7p equation: [x] : 3ohdcoa + coa --> accoa + tdcoa R_ACACT8p subsystem: Fatty Acid Metabolism R_ACACT8p equation: [x] : 3ohodcoa + coa --> accoa + pmtcoa R_FAOXC246226x subsystem: Fatty acid oxidation, peroxisome R_FAOXC246226x equation: [x] : coa + h2o + nad + o2 + tethex3coa --> accoa + c226coa + h + h2o2 + nadh R_ACACT5p subsystem: Fatty Acid Metabolism R_ACACT5p equation: [x] : 3oddcoa + coa --> accoa + dcacoa R_FAOXC260240x subsystem: Fatty acid oxidation, peroxisome R_FAOXC260240x equation: [x] : coa + h2o + hexccoa + nad + o2 --> accoa + h + h2o2 +…
product: 226284
reactant: 226017
reactant: 225969
reactant: 225981
reversible: false
reactant: 226005
reactant: 225957
product: 226296
product: 226441

226478
type: SpeciesReference
stoichiometry: 4.0
species: 182394

182394
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Octanoyl-CoA (n-C8:0CoA)_C29H46N7O17P3S

226539
type: SpeciesReference
stoichiometry: 1.0
species: 170314

170314
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Dodecanoyl-CoA (n-C12:0CoA)_C33H54N7O17P3S

226454
type: SpeciesReference
stoichiometry: 2.0
species: 183905

183905
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Propanoyl-CoA_C24H36N7O17P3S

226551
type: SpeciesReference
stoichiometry: 39.0
species: 164643

164643
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Acetyl-CoA_C23H34N7O17P3S

226405
type: SpeciesReference
stoichiometry: 1.0
species: 167399

167399
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: cervonyl coenzyme A_C43H62N7O17P3S

226151
type: SpeciesReference
stoichiometry: 1.0
species: 176168

176168
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Hexacosanoyl-CoA (n-C26:0CoA)_C47H82N7O17P3S

226490
type: SpeciesReference
stoichiometry: 2.0
species: 187120

187120
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: timnodonyl coenzyme A_C41H60N7O17P3S

226429
type: SpeciesReference
stoichiometry: 1.0
species: 166676

166676
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: C20:4-CoA_C41H62N7O17P3S

226236
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species: 186634

186634
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initial amount: NaN
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name: tetracosatetraenoyl coenzyme A_C45H70N7O17P3S

226357
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species: 182563

182563
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226393
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species: 186393

186393
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initial concentration: NaN
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226320
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species: 186041

186041
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226224
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species: 186441

186441
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226248
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species: 179739

179739
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has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: gamma-linolenoyl-CoA_C39H60N7O17P3S

226126
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species: 167399

226515
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species: 187428

226114
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species: 162169

162169
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has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: _3-Oxododecanoyl-CoA_C33H52N7O18P3S

226332
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species: 170145

226308
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stoichiometry: 1.0
species: 179425

226029
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186489
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226272
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species: 186561

186561
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initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: tetracosapentaenoyl coenzyme A, n-6_C45H68N7O17P3S

226199
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species: 162157

162157
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initial amount: NaN
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name: _3-Oxodecanoyl-CoA_C31H48N7O18P3S

226187
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species: 181498

181498
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initial concentration: NaN
initial amount: NaN
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name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

226563
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170000
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has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Decanoyl-CoA (n-C10:0CoA)_C31H50N7O17P3S

226417
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species: 165593

165593
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initial concentration: NaN
initial amount: NaN
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name: adrenyl coenzyme A_C43H66N7O17P3S

226065
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species: 170145

226369
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166579
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initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: arachidyl coenzyme A_C41H70N7O17P3S

226089
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species: 168581

168581
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has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Coenzyme A_C21H32N7O16P3S

226260
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species: 162181

162181
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: _3-Oxohexadecanoyl-CoA_C37H60N7O18P3S

226053
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species: 182214

226466
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species: 168268

168268
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: clupanodonyl CoA_C43H64N7O17P3S

226101
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stoichiometry: 1.0
species: 185945

226077
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stoichiometry: 1.0
species: 166579

226527
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stoichiometry: 1.0
species: 179739

226175
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species: 162217

162217
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: _3-Oxotetradecanoyl-CoA_C35H56N7O18P3S

225993
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stoichiometry: 1.0
species: 182094

182094
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: nervonyl coenzyme A_C45H76N7O17P3S

226211
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species: 187120

226163
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species: 162193

162193
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: _3-Oxooctadecanoyl-CoA_C39H64N7O18P3S

226344
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species: 181546

181546
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

226041
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stoichiometry: 1.0
species: 186041

226139
type: SpeciesReference
stoichiometry: 1.0
species: 165593

226502
type: SpeciesReference
stoichiometry: 35.0
species: 175806

226381
type: SpeciesReference
stoichiometry: 1.0
species: 185945

226284
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species: 171172

171172
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S

226017
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species: 175698

225969
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species: 162205

162205
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: _3-Oxohexacosyl-CoA_C47H80N7O18P3S

225981
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species: 184266

184266
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: pristanoyl coa_C40H68N7O17P3S

226005
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stoichiometry: 1.0
species: 179425

225957
type: SpeciesReference
stoichiometry: 1.0
species: 183772

183772
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S

226296
type: SpeciesReference
stoichiometry: 2.0
species: 183772

226441
type: SpeciesReference
stoichiometry: 23.0
species: 175602

187320
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Testosterone_C19H28O2

171306
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Dolichyl beta-D-glucosyl phosphate, human liver homolog_C1140H1868O90P10

948935
type: Reaction
modifier: 222271
modifier: 222175
modifier: 222295
modifier: 221911
reactant: 221681
is: ENSMUSG00000018796.5
modifier: 222332
modifier: 222368
modifier: 222404
reactant: 221657
modifier: 222428
modifier: 221862
modifier: 221947
modifier: 222235
modifier: 222139
modifier: 222151
modifier: 222259
product: 221753
modifier: 222223
product: 221765
modifier: 222031
modifier: 222392
product: 221717
product: 221741
modifier: 221814
modifier: 221838
modifier: 222115
modifier: 222067
reactant: 221669
modifier: 221899
modifier: 221959
modifier: 222440
modifier: 221983
modifier: 222163
modifier: 222356
product: 221729
modifier: 222380
notes: R_FACOAL2252 subsystem: Fatty acid activation R_FACOAL2252 equation: [c] : atp + clpnd + coa <==> amp + clpndcoa + ppi R_FACOAL226 subsystem: Fatty acid activation R_FACOAL226 equation: [c] : atp + coa + crvnc <==> amp + c226coa + ppi R_FACOAL1812 subsystem: Fatty acid activation R_FACOAL1812 equation: [c] : atp + coa + vacc <==> amp + ppi + vacccoa R_FACOAL161 subsystem: Fatty acid activation R_FACOAL161 equation: [c] : atp + coa + hdcea <==> amp + hdcoa + ppi R_FACOAL2251 subsystem: Fatty acid activation R_FACOAL2251 equation: [c] : atp + coa + dcsptn1 <==> amp + dcsptn1coa + ppi R_FACOAL180i subsystem: Fatty acid activation R_FACOAL180i equation: [c] : atp + coa + ocdca --> amp + ppi + stcoa R_FACOAL260 subsystem: Fatty acid activation R_FACOAL260 equation: [c] : atp + coa + hexc <==> amp + hexccoa + ppi R_FACOAL241 subsystem: Fatty acid activation R_FACOAL241 equation: [c] : atp + coa + nrvnc <==> amp + nrvnccoa + ppi R_FACOAL181i subsystem: Fatty acid activation R_FACOAL181i equation: [c] : atp + coa + ocdcea --> amp + odecoa + ppi R_FACOAL245_2 subsystem: Fatty acid activation R_FACOAL245_2 equation: [c] : atp + coa + tetpent3 <==> amp + ppi + tetpent3coa R_FACOAL245_1 subsystem: Fatty acid activation R_FACOAL245_1 equation: [c] : atp + coa + tetpent6 <==> amp + ppi + tetpent6coa R_FACOAL2042 subsystem: Fatty acid activation R_FACOAL2042 equation: [c] : atp + coa + eicostet <==> amp + eicostetcoa + ppi R_FACOAL224 subsystem: Fatty acid activation R_FACOAL224 equation: [c] : adrn + atp + coa <==> adrncoa + amp + ppi R_FACOAL246_1 subsystem: Fatty acid activation R_FACOAL246_1 equation: [c] : atp + coa + tethex3 <==> amp + ppi + tethex3coa R_FACOAL204 subsystem: Fatty acid activation R_FACOAL204 equation: [c] : arachd + atp + coa <==> amp + arachdcoa + ppi R_FACOAL1831 subsystem: Fatty acid activation R_FACOAL1831 equation: [c] : atp + coa + lnlncg <==> amp + lnlncgcoa + ppi R_FACOAL203 subsystem: Fatty acid activation R_FACOAL203 equation: [c] : atp + coa + dln…
reactant: 221645
modifier: 221789
modifier: 221802
modifier: 222007
product: 221705
modifier: 222199
modifier: 222019
reactant: 221693
modifier: 221995
modifier: 222103
modifier: 221850
modifier: 222320
modifier: 222055
modifier: 221935
modifier: 222127
modifier: 222283
modifier: 222344
modifier: 222079
modifier: 222416
modifier: 222043
modifier: 221923
modifier: 222211
reversible: false
modifier: 221887
modifier: 221971
reactant: 221633
is: http://identifiers.org/ec-code/6.2.1.3
modifier: 222187
modifier: 222247
modifier: 222091
modifier: 222307
modifier: 221777
modifier: 221875
fast: false
modifier: 221826

171039
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: dihomo-gamma-linolenic acid (n-6)_C20H33O2

179582
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: linoleic acid (all cis C18:2) n-6_C18H31O2

167375
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: cervonyl coenzyme A_C43H62N7O17P3S

221681
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species: 182418

182418
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has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: octadecanoate (n-C18:0)_C18H35O2

179642
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: alpha-Linolenic acid, C18:3, n-3_C18H29O2

168896
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initial amount: NaN
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179533
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initial amount: NaN
in compartment: 160514
name: linoelaidyl coenzyme A_C39H62N7O17P3S

221657
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species: 166616

168232
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initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: clupanodonic acid_C22H33O2

186017
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boundary condition: false
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initial amount: NaN
in compartment: 160514
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187094
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: timnodonyl coenzyme A_C41H60N7O17P3S

166555
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initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: arachidyl coenzyme A_C41H70N7O17P3S

186005
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: stearidonic acid C18:4, n-3_C18H27O2

171981
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: eicosatetranoic acid_C20H31O2

221753
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species: 166219

188152
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: vaccenyl coenzyme A_C39H64N7O17P3S

221765
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species: 183917

179654
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: alpha-Linolenoyl-CoA_C39H60N7O17P3S

186610
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: tetracosatetraenoyl coenzyme A_C45H70N7O17P3S

221717
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species: 182539

182539
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Octadecenoyl-CoA (n-C18:1CoA)_C39H64N7O17P3S

221741
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species: 185921

185921
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S

182069
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: nervonyl coenzyme A_C45H76N7O17P3S

172041
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: elaidic acid_C18H33O2

179521
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: linoelaidic acid (all trans C18:2)_C18H31O2

221669
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species: 166904

179376
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: lignoceric acid_C24H47O2

179594
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: linoleic coenzyme A_C39H62N7O17P3S

186598
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: tetracosatetraenoic acid n-6_C24H39O2

221729
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species: 183748

183748
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S

165533
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: adrenic acid_C22H35O2

221645
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stoichiometry: 4.0
species: 168509

170121
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: docosa-4,7,10,13,16-pentaenoyl coenzyme A_C43H64N7O17P3S

179703
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: gamma-linolenic acid_C18H29O2

186537
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: tetracosapentaenoyl coenzyme A, n-6_C45H68N7O17P3S

221705
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stoichiometry: 1.0
species: 166652

182044
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: nervonic acid_C24H45O2

176132
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: hexacosanoate (n-C26:0)_C26H51O2

221693
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species: 182443

182443
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: octadecenoate (n-C18:1)_C18H33O2

171993
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: eicosatetranoyl coenzyme A_C41H62N7O17P3S

175986
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Hexadecenoate (n-C16:1)_C16H29O2

186417
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: tetracosahexaenoic acid, n-3_C24H35O2

165569
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: adrenyl coenzyme A_C43H66N7O17P3S

171051
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dihomo-gamma-linolenyl coenzyme A_C41H64N7O17P3S

176144
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Hexacosanoyl-CoA (n-C26:0CoA)_C47H82N7O17P3S

179401
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: lignocericyl coenzyme A_C45H78N7O17P3S

166531
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Arachidic acid_C20H39O2

179715
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: gamma-linolenoyl-CoA_C39H60N7O17P3S

186453
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: tetracosapentaenoic acid, n-3_C24H37O2

176024
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Hexadecenoyl-CoA (n-C16:1CoA)_C37H60N7O17P3S

186525
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: tetracosapentaenoic acid, n-6_C24H37O2

221633
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species: 175938

175938
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Hexadecanoate (n-C16:0)_C16H31O2

170109
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: docosa-4,7,10,13,16-pentaenoic acid (n-6)_C22H33O2

168244
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: clupanodonyl CoA_C43H64N7O17P3S

182515
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514

188140
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: vaccenic acid_C18H33O2

186429
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: tetracosahexaenoyl coenzyme A_C45H66N7O17P3S

187082
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: timnodonic acid C20:5, n-3_C20H29O2

186465
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: tetracosapentaenoyl coenzyme A, n-3_C45H68N7O17P3S

186113
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Succinate_C4H4O4

167230
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Biocytin_C16H28N4O4S

949115
type: Reaction
product: 223967
reactant: 223943
reactant: 223847
reactant: 223895
product: 223991
notes: R_NDPK7m subsystem: Nucleotides R_NDPK7m equation: [m] : atp + dcdp <==> adp + dctp R_NDPK8m subsystem: Nucleotides R_NDPK8m equation: [m] : atp + dadp <==> adp + datp R_NDPK6m subsystem: Nucleotides R_NDPK6m equation: [m] : atp + dudp <==> adp + dutp R_NDPK4m subsystem: Nucleotides R_NDPK4m equation: [m] : atp + dtdp <==> adp + dttp R_NDPK2m subsystem: Nucleotides R_NDPK2m equation: [m] : atp + udp <==> adp + utp R_NDPK10m subsystem: Nucleotides R_NDPK10m equation: [m] : atp + didp <==> adp + ditp R_NDPK3m subsystem: Nucleotides R_NDPK3m equation: [m] : atp + cdp <==> adp + ctp R_NDPK5m subsystem: Nucleotides R_NDPK5m equation: [m] : atp + dgdp <==> adp + dgtp R_NDPK1m subsystem: Nucleotides R_NDPK1m equation: [m] : atp + gdp <==> adp + gtp R_NDPK9m subsystem: Nucleotides R_NDPK9m equation: [m] : atp + idp <==> adp + itp
reversible: true
product: 224027
reactant: 223871
product: 224039
product: 224015
reactant: 223931
reactant: 223883
fast: false
product: 224087
is: ENSMUSG00000024177.5
product: 224003
reactant: 223955
product: 224063
is: ENSMUSG00000037601.3
reactant: 223859
product: 224075
product: 224051
reactant: 223907
product: 223979
reactant: 223919
is: http://identifiers.org/ec-code/2.7.4.6
reactant: 223835

223967
type: SpeciesReference
stoichiometry: 1.0
species: 170193

170193
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: dCTP_C9H12N3O13P3

223943
type: SpeciesReference
stoichiometry: 1.0
species: 170037

170037
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: dCDP_C9H12N3O10P2

223847
type: SpeciesReference
stoichiometry: 1.0
species: 171583

171583
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: dTDP_C10H13N2O11P2

223895
type: SpeciesReference
stoichiometry: 1.0
species: 187632

187632
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: UDP_C9H11N2O12P2

223991
type: SpeciesReference
stoichiometry: 1.0
species: 171692

224027
type: SpeciesReference
stoichiometry: 10.0
species: 165411

223871
type: SpeciesReference
stoichiometry: 1.0
species: 167663

167663
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: CDP_C9H12N3O11P2

224039
type: SpeciesReference
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species: 188116

188116
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: UTP_C9H11N2O15P3

224015
type: SpeciesReference
stoichiometry: 1.0
species: 169963

169963
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: dATP_C10H12N5O12P3

223931
type: SpeciesReference
stoichiometry: 10.0
species: 166928

223883
type: SpeciesReference
stoichiometry: 1.0
species: 174154

224087
type: SpeciesReference
stoichiometry: 1.0
species: 171836

171836
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: dUTP_C9H11N2O14P3

224003
type: SpeciesReference
stoichiometry: 1.0
species: 169628

169628
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: CTP_C9H12N3O14P3

223955
type: SpeciesReference
stoichiometry: 1.0
species: 169853

169853
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: dADP_C10H12N5O9P2

224063
type: SpeciesReference
stoichiometry: 1.0
species: 171015

171015
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: dITP_C10H11N4O13P3

223859
type: SpeciesReference
stoichiometry: 1.0
species: 177192

177192
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: IDP_C10H11N4O11P2

224075
type: SpeciesReference
stoichiometry: 1.0
species: 170544

170544
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: dGTP_C10H12N5O13P3

224051
type: SpeciesReference
stoichiometry: 1.0
species: 177495

177495
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: ITP_C10H11N4O14P3

223907
type: SpeciesReference
stoichiometry: 1.0
species: 170906

170906
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: dIDP_C10H11N4O10P2

223979
type: SpeciesReference
stoichiometry: 1.0
species: 175458

223919
type: SpeciesReference
stoichiometry: 1.0
species: 170423

170423
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: dGDP_C10H12N5O10P2

223835
type: SpeciesReference
stoichiometry: 1.0
species: 171728

171728
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: dUDP_C9H11N2O11P2

188249
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Vitamin D3_C27H44O

947444
type: Reaction
product: 209704
is: http://identifiers.org/ec-code/6.4.1.4
reactant: 209668
is: ENSMUSG00000027709.2
reversible: true
product: 209740
reactant: 209680
name: methylcrotonoyl-CoA carboxylase, mitochondrial
notes: R_MCCCrm subsystem: Valine, Leucine, and Isoleucine Metabolism R_MCCCrm equation: [m] : 3mb2coa + atp + hco3 <==> 3mgcoa + adp + h + pi
reactant: 209692
fast: false
product: 209716
product: 209728
is: ENSMUSG00000021646.6

209704
type: SpeciesReference
stoichiometry: 1.0
species: 183700

209668
type: SpeciesReference
stoichiometry: 1.0
species: 175902

209740
type: SpeciesReference
stoichiometry: 1.0
species: 175770

209680
type: SpeciesReference
stoichiometry: 1.0
species: 162023

209692
type: SpeciesReference
stoichiometry: 1.0
species: 166928

209716
type: SpeciesReference
stoichiometry: 1.0
species: 165411

209728
type: SpeciesReference
stoichiometry: 1.0
species: 162035

182056
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: nervonic acid_C24H45O2

955427
type: Reaction
reactant: 285705
reactant: 285681
product: 285994
product: 286127
product: 286151
reactant: 285873
reactant: 285957
reactant: 285717
reversible: false
product: 286187
modifier: 286283
reactant: 285753
reactant: 285729
fast: false
reactant: 285837
reactant: 285765
product: 286079
product: 286235
reactant: 285657
product: 285970
modifier: 286331
product: 286223
reactant: 285693
reactant: 285849
reactant: 285933
product: 286163
reactant: 285632
product: 286199
reactant: 285945
product: 286043
product: 286115
reactant: 285825
product: 286091
reactant: 285644
product: 285982
modifier: 286295
modifier: 286307
reactant: 285741
product: 286018
reactant: 285909
modifier: 286319
reactant: 285669
reactant: 285801
product: 286139
reactant: 285813
product: 286055
product: 286211
reactant: 285789
reactant: 285885
is: http://identifiers.org/ec-code/1.1.1.35
reactant: 285861
product: 286103
product: 286271
reactant: 285897
is: http://identifiers.org/ec-code/1.3.99.3
product: 286006
product: 286259
product: 286175
product: 286247
product: 286030
notes: R_FAOXC2251836x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2251836x equation: [x] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_FAOXC180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC180x equation: [x] : coa + h2o + nad + o2 + stcoa --> accoa + h + h2o2 + nadh + pmtcoa R_FAOXC241181x subsystem: Fatty acid oxidation, peroxisome R_FAOXC241181x equation: [x] : (3) coa + (3) h2o + (3) nad + nrvnccoa + (3) o2 --> (3) accoa + (3) h + (3) h2o2 + (3) nadh + odecoa R_PEROXx subsystem: Fatty acid oxidation, peroxisome R_PEROXx equation: [x] : (3) coa + (3) h2o + (3) nad + (2) o2 + pristcoa --> accoa + dmnoncoa + (3) h + (2) h2o2 + (3) nadh + (2) ppcoa R_FAOXC2452253x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2452253x equation: [x] : coa + h2o + nad + o2 + tetpent3coa --> accoa + clpndcoa + h + h2o2 + nadh R_FAOXC2252053x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2252053x equation: [x] : coa + dcsptn1coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + tmndnccoa R_FAOXC183806x subsystem: Fatty acid oxidation, peroxisome R_FAOXC183806x equation: [x] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC200180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC200180x equation: [x] : arachcoa + coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + stcoa R_FAOXC246226x subsystem: Fatty acid oxidation, peroxisome R_FAOXC246226x equation: [x] : coa + h2o + nad + o2 + tethex3coa --> accoa + c226coa + h + h2o2 + nadh R_FAOXC260240x subsystem: Fatty acid oxidation, peroxisome R_FAOXC260240x equation: [x] : coa + h2o + hexccoa + nad + o2 --> accoa + h + h2o2 + lgnccoa + nadh R_FAOXC240200x subsystem: Fatty acid oxidation, peroxisome R_FAOXC240200x equation: [x] : (2) coa + (2) h2o + lgnccoa + (2) nad + (2) o2 --> (2) accoa + arachcoa + (2) h + (2) h2o2 + (2) nadh R_FAOXC2452256x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2452256x equation: [x] : coa + …
product: 286067
is: ENSMUSG00000024507.5
reactant: 285777
reactant: 285921

285705
type: SpeciesReference
stoichiometry: 1.0
species: 186041

285681
type: SpeciesReference
stoichiometry: 35.0
species: 175698

285994
type: SpeciesReference
stoichiometry: 2.0
species: 181619

181619
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3

286127
type: SpeciesReference
stoichiometry: 1.0
species: 165593

286151
type: SpeciesReference
stoichiometry: 23.0
species: 175602

285873
type: SpeciesReference
stoichiometry: 1.0
species: 187120

285957
type: SpeciesReference
stoichiometry: 1.0
species: 186561

285717
type: SpeciesReference
stoichiometry: 25.0
species: 182214

286187
type: SpeciesReference
stoichiometry: 1.0
species: 168268

285753
type: SpeciesReference
stoichiometry: 1.0
species: 166579

285729
type: SpeciesReference
stoichiometry: 1.0
species: 188778

188778
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: zymosterol intermediate 2_C27H42O

285837
type: SpeciesReference
stoichiometry: 35.0
species: 181498

285765
type: SpeciesReference
stoichiometry: 35.0
species: 168581

286079
type: SpeciesReference
stoichiometry: 1.0
species: 166579

286235
type: SpeciesReference
stoichiometry: 1.0
species: 181607

285657
type: SpeciesReference
stoichiometry: 1.0
species: 182094

285970
type: SpeciesReference
stoichiometry: 1.0
species: 171172

164390
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Acetoacetyl-CoA_C25H36N7O18P3S

286223
type: SpeciesReference
stoichiometry: 35.0
species: 175806

285693
type: SpeciesReference
stoichiometry: 1.0
species: 186489

285849
type: SpeciesReference
stoichiometry: 1.0
species: 181667

285933
type: SpeciesReference
stoichiometry: 2.0
species: 181680

181680
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3

286163
type: SpeciesReference
stoichiometry: 1.0
species: 167918

167918
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598

285632
type: SpeciesReference
stoichiometry: 1.0
species: 183772

286199
type: SpeciesReference
stoichiometry: 3.0
species: 182394

285945
type: SpeciesReference
stoichiometry: 1.0
species: 175794

286043
type: SpeciesReference
stoichiometry: 1.0
species: 170145

286115
type: SpeciesReference
stoichiometry: 1.0
species: 167399

285825
type: SpeciesReference
stoichiometry: 1.0
species: 176168

286091
type: SpeciesReference
stoichiometry: 1.0
species: 185945

285644
type: SpeciesReference
stoichiometry: 1.0
species: 184266

285982
type: SpeciesReference
stoichiometry: 1.0
species: 183772

161867
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598

285741
type: SpeciesReference
stoichiometry: 2.0
species: 170145

286018
type: SpeciesReference
stoichiometry: 3.0
species: 175698

285909
type: SpeciesReference
stoichiometry: 1.0
species: 186634

285669
type: SpeciesReference
stoichiometry: 1.0
species: 179425

285801
type: SpeciesReference
stoichiometry: 1.0
species: 167399

286139
type: SpeciesReference
stoichiometry: 1.0
species: 166676

285813
type: SpeciesReference
stoichiometry: 1.0
species: 165593

286055
type: SpeciesReference
stoichiometry: 35.0
species: 181546

286211
type: SpeciesReference
stoichiometry: 2.0
species: 187120

285789
type: SpeciesReference
stoichiometry: 1.0
species: 186706

186706
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598

285885
type: SpeciesReference
stoichiometry: 1.0
species: 186441

285861
type: SpeciesReference
stoichiometry: 1.0
species: 167906

167906
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598

286103
type: SpeciesReference
stoichiometry: 1.0
species: 188790

188790
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: zymosterol_C27H44O

286271
type: SpeciesReference
stoichiometry: 33.0
species: 164643

285897
type: SpeciesReference
stoichiometry: 2.0
species: 175806

286006
type: SpeciesReference
stoichiometry: 1.0
species: 179425

286259
type: SpeciesReference
stoichiometry: 1.0
species: 179739

286175
type: SpeciesReference
stoichiometry: 2.0
species: 183905

286247
type: SpeciesReference
stoichiometry: 1.0
species: 170870

286030
type: SpeciesReference
stoichiometry: 1.0
species: 186041

286067
type: SpeciesReference
stoichiometry: 1.0
species: 182563

285777
type: SpeciesReference
stoichiometry: 1.0
species: 185945

285921
type: SpeciesReference
stoichiometry: 1.0
species: 179739

178714
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 2_C39H63N3O28X

955752
type: Reaction
reactant: 290652
reactant: 290640
product: 290664
reactant: 290628
notes: R_GBAl subsystem: Sphingolipid Metabolism R_GBAl equation: [l] : gluside_hs + h2o --> crm_hs + glc-D R_GBA subsystem: Sphingolipid Metabolism R_GBA equation: [c] : gluside_hs + h2o --> crm_hs + glc-D
reactant: 290616
product: 290676
is: ENSMUSG00000028048.4
is: http://identifiers.org/ec-code/3.2.1.45
product: 290700
reversible: false
fast: false
product: 290688

290652
type: SpeciesReference
stoichiometry: 1.0
species: 174552

174552
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO

290640
type: SpeciesReference
stoichiometry: 1.0
species: 175614

290664
type: SpeciesReference
stoichiometry: 1.0
species: 168763

168763
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

290628
type: SpeciesReference
stoichiometry: 1.0
species: 175650

290616
type: SpeciesReference
stoichiometry: 1.0
species: 174528

174528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO

290676
type: SpeciesReference
stoichiometry: 1.0
species: 174310

290700
type: SpeciesReference
stoichiometry: 1.0
species: 174274

290688
type: SpeciesReference
stoichiometry: 1.0
species: 168738

177265
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Imidazole-4-acetate_C5H5N2O2

174358
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Glucuronate_C6H9O7

950450
type: Reaction
product: 237599
reactant: 237587
notes: R_MMMm subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMMm equation: [m] : mmcoa-R <==> succoa
is: ENSMUSG00000023921.6
is: http://identifiers.org/ec-code/5.4.99.2
fast: false
reversible: true
name: methylmalonyl-CoA mutase

237599
type: SpeciesReference
stoichiometry: 1.0
species: 186138

237587
type: SpeciesReference
stoichiometry: 1.0
species: 181090

181090
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: (R)-Methylmalonyl-CoA_C25H35N7O19P3S

167784
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Cholesta-7,24-dien-3beta-ol_C27H44O

176842
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: heparan sulfate, precursor 1_C31H49NO25X

187283
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Tryptophan_C11H12N2O2

953877
type: Reaction
is: ENSMUSG00000037940.7
reversible: false
reactant: 270846
reactant: 270834
product: 270870
notes: R_MI34PP subsystem: Inositol Phosphate Metabolism R_MI34PP equation: [c] : h2o + mi34p --> mi3p-D + pi
is: http://identifiers.org/ec-code/3.1.3.66
product: 270858
name: inositol-3,4-bisphosphate 4-phosphatase
fast: false

270846
type: SpeciesReference
stoichiometry: 1.0
species: 175614

270834
type: SpeciesReference
stoichiometry: 1.0
species: 180994

180994
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1D-myo-Inositol 3,4-bisphosphate_C6H10O12P2

270870
type: SpeciesReference
stoichiometry: 1.0
species: 181006

181006
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1D-myo-Inositol 3-phosphate_C6H11O9P

270858
type: SpeciesReference
stoichiometry: 1.0
species: 183652

169654
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Hydrogen cyanide_CHN

951979
type: Reaction
product: 251066
is: ENSMUSG00000079427.2
is: http://identifiers.org/ec-code/6.3.3.2
reactant: 251054
reactant: 251042
notes: R_FTHFCL subsystem: Folate Metabolism R_FTHFCL equation: [c] : 5fthf + atp --> adp + methf + pi
product: 251078
name: _5-formethyltetrahydrofolate cyclo-ligase
fast: false
is: ENSMUSG00000066442.5
product: 251090
reversible: false

251066
type: SpeciesReference
stoichiometry: 1.0
species: 183652

251054
type: SpeciesReference
stoichiometry: 1.0
species: 163088

251042
type: SpeciesReference
stoichiometry: 1.0
species: 166904

251078
type: SpeciesReference
stoichiometry: 1.0
species: 180764

251090
type: SpeciesReference
stoichiometry: 1.0
species: 165387

168932
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate A (GalNAc4S-GlcA), B (IdoA2S-GalNAc4S), and E (GalNAc4,6diS-GlcA), precursor 1_C31H47NO31S2X

184675
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: pendtadenoyl carnitine_C22H43NO4

172379
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Ethanolamine phosphate_C2H7NO4P

161975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3-Hydroxy-N6,N6,N6-trimethyl-L-lysine_C9H20N2O3

947793
type: Reaction
reactant: 212451
product: 212488
reversible: true
reactant: 212463
is: ENSMUSG00000042371.5
is: ENSMUSG00000033255.5
fast: false
is: ENSMUSG00000020229.4
is: ENSMUSG00000000792.1
is: ENSMUSG00000041644.7
name: glucose transport via sodium symport
is: ENSMUSG00000020226.7
notes: R_GLCt4 subsystem: Transport, Extracellular R_GLCt4 equation: glc-D[e] + na1[e] <==> glc-D[c] + na1[c]
product: 212475

212451
type: SpeciesReference
stoichiometry: 1.0
species: 181389

212488
type: SpeciesReference
stoichiometry: 1.0
species: 174274

212463
type: SpeciesReference
stoichiometry: 1.0
species: 174286

212475
type: SpeciesReference
stoichiometry: 1.0
species: 181377

954694
type: Reaction
is: ENSMUSG00000026348.6
reversible: false
is: http://identifiers.org/ec-code/4.1.1.45
name: picolinic acid decarboxylase
product: 278997
fast: false
product: 278985
notes: R_PCLAD subsystem: Tryptophan metabolism R_PCLAD equation: [c] : cmusa + h --> am6sa + co2
reactant: 278973
reactant: 278961

278997
type: SpeciesReference
stoichiometry: 1.0
species: 166147

166147
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _2-Aminomuconate 6-semialdehyde_C6H7NO3

278985
type: SpeciesReference
stoichiometry: 1.0
species: 168436

278973
type: SpeciesReference
stoichiometry: 1.0
species: 175722

278961
type: SpeciesReference
stoichiometry: 1.0
species: 168424

168424
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _2-Amino-3-carboxymuconate semialdehyde_C7H6NO5

179763
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: gamma-linolenyl carnitine_C25H43NO4

164739
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: alpha GalNAc globoside (homo sapiens)_C52H92N3O27FULLRCO

187887
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: UMP_C9H11N2O9P

180548
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: D-Mannose_C6H12O6

188020
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Urea_CH4N2O

950018
type: Reaction
is: ENSMUSG00000072548.3
is: ENSMUSG00000040952.7
product: 232692
product: 232668
reactant: 232644
fast: false
is: ENSMUSG00000068689.5
reversible: false
product: 232656
is: ENSMUSG00000072528.2
is: ENSMUSG00000080006.1
product: 232680
reactant: 232632
reactant: 232619
is: ENSMUSG00000069391.3
notes: R_ST3GAL61g subsystem: Blood Group Biosynthesis R_ST3GAL61g equation: [g] : cmpacna + gal14acglcgalgluside_hs --> acngal14acglcgalgluside_hs + cmp + h R_ST3GAL62g subsystem: Blood Group Biosynthesis R_ST3GAL62g equation: [g] : cmpacna + galacglcgal14acglcgalgluside_hs --> acngalacglcgal14acglcgalgluside_hs + cmp + h
is: ENSMUSG00000080059.1

232692
type: SpeciesReference
stoichiometry: 2.0
species: 168340

168340
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: CMP_C9H12N3O8P

232668
type: SpeciesReference
stoichiometry: 2.0
species: 175746

232644
type: SpeciesReference
stoichiometry: 1.0
species: 173655

173655
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: i-antigen_C58H102N3O32FULLRCO

232656
type: SpeciesReference
stoichiometry: 1.0
species: 165148

165148
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550

232680
type: SpeciesReference
stoichiometry: 1.0
species: 165160

165160
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: VI3NeuAc-nLc6Cer_C69H118N4O40FULLRCO

232632
type: SpeciesReference
stoichiometry: 2.0
species: 168388

168388
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: CMP-N-acetylneuraminate_C20H29N4O16P

232619
type: SpeciesReference
stoichiometry: 1.0
species: 173557

173557
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550

953829
type: Reaction
product: 270291
is: ENSMUSG00000052151.4
reactant: 270267
fast: false
is: ENSMUSG00000028517.7
notes: R_PPAP subsystem: Triacylglycerol Synthesis R_PPAP equation: [c] : h2o + pa_hs --> dag_hs + pi
name: phosphatidic acid phosphatase
reactant: 270255
is: ENSMUSG00000021759.6
product: 270279
is: http://identifiers.org/ec-code/3.1.3.4
reversible: false

270291
type: SpeciesReference
stoichiometry: 1.0
species: 183652

270267
type: SpeciesReference
stoichiometry: 1.0
species: 175614

270255
type: SpeciesReference
stoichiometry: 1.0
species: 182755

270279
type: SpeciesReference
stoichiometry: 1.0
species: 169878

167097
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Bilirubin beta-diglucuronide_C45H50N4O18

160720
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: _10-formyltetrahydrofolate-[Glu](7)_C50H57N13O25

185520
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: D-Serine_C3H7NO3

176265
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Hydroxymethylbilane_C40H38N4O17

169667
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Hydrogen cyanide_CHN

175058
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GlcNAc-alpha-1,4-Core 2_C30H50N3O20X

945902
type: Reaction
product: 195490
reversible: false
product: 195478
fast: false
product: 195466
reactant: 195442
reactant: 195430
product: 195502
is: ENSMUSG00000029263.7
reactant: 195418
reactant: 195454
notes: R_M4BET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4BET2er equation: [r] : mem2emgacpail_hs + pe_hs --> dag_hs + m(em)3gacpail_hs R_H6_APOS_ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6_APOS_ET2er equation: [r] : em3gacpail_hs + pe_hs --> dag_hs + emem2gacpail_hs R_H7ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7ET2er equation: [r] : em2emgacpail_hs + pe_hs --> dag_hs + gpi_hs

195490
type: SpeciesReference
stoichiometry: 1.0
species: 172113

172113
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (phosphoethanolaminyl-mannosyl),(phosphoethanolaminyl)-dimannosyl-glucosaminyl-acylphosphatidylinositol (H7')_C53H100N3O35P3FULLRCO2FULLR2CO2

195478
type: SpeciesReference
stoichiometry: 3.0
species: 169914

169914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2

195466
type: SpeciesReference
stoichiometry: 1.0
species: 175108

195442
type: SpeciesReference
stoichiometry: 1.0
species: 180596

195430
type: SpeciesReference
stoichiometry: 3.0
species: 183337

195502
type: SpeciesReference
stoichiometry: 1.0
species: 180282

195418
type: SpeciesReference
stoichiometry: 1.0
species: 172101

195454
type: SpeciesReference
stoichiometry: 1.0
species: 172077

161160
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _2,3-Disphospho-D-glycerate_C3H3O10P2

181301
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: reducing GlcNAc removed form of n2m2nmasn (w/o peptide)_C50H84N4O36

168824
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Carnitine_C7H15NO3

168280
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: clupanodonyl carnitine_C29H47NO4

952687
type: Reaction
is: ENSMUSG00000031884.7
product: 259816
is: ENSMUSG00000058346.5
reactant: 259780
is: ENSMUSG00000062826.5
is: ENSMUSG00000050097.5
product: 259828
is: http://identifiers.org/ec-code/3.1.1.1
is: ENSMUSG00000031877.7
product: 259804
name: Carboxylesterase (cocaine) (er)
is: ENSMUSG00000061825.2
is: ENSMUSG00000055730.6
notes: R_COKECBESr subsystem: Alkaloid biosynthesis II R_COKECBESr equation: [r] : coke + h2o --> bz + egme + h
is: ENSMUSG00000031886.6
fast: false
reactant: 259792
reversible: false

259816
type: SpeciesReference
stoichiometry: 1.0
species: 167363

167363
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Benzoate_C7H5O2

259780
type: SpeciesReference
stoichiometry: 1.0
species: 168593

168593
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: cocaine_C17H21NO4

259828
type: SpeciesReference
stoichiometry: 1.0
species: 175794

259804
type: SpeciesReference
stoichiometry: 1.0
species: 171969

259792
type: SpeciesReference
stoichiometry: 1.0
species: 175686

169393
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 4_C31H46NO38S4

956125
type: Reaction
reactant: 293524
is: ENSMUSG00000029098.7
product: 293609
product: 293585
product: 293597
reactant: 293536
product: 293621
notes: R_PEROXx subsystem: Fatty acid oxidation, peroxisome R_PEROXx equation: [x] : (3) coa + (3) h2o + (3) nad + (2) o2 + pristcoa --> accoa + dmnoncoa + (3) h + (2) h2o2 + (3) nadh + (2) ppcoa
reactant: 293512
product: 293633
reactant: 293561
name: peroxisomal lumped long chain fatty acid oxidation
product: 293573
reactant: 293548
fast: false
reversible: false

293524
type: SpeciesReference
stoichiometry: 3.0
species: 175698

293609
type: SpeciesReference
stoichiometry: 2.0
species: 183905

293585
type: SpeciesReference
stoichiometry: 3.0
species: 181546

293597
type: SpeciesReference
stoichiometry: 2.0
species: 175602

293536
type: SpeciesReference
stoichiometry: 2.0
species: 182214

293621
type: SpeciesReference
stoichiometry: 3.0
species: 175806

293512
type: SpeciesReference
stoichiometry: 1.0
species: 184266

293633
type: SpeciesReference
stoichiometry: 1.0
species: 164643

293561
type: SpeciesReference
stoichiometry: 3.0
species: 181498

293573
type: SpeciesReference
stoichiometry: 1.0
species: 171172

293548
type: SpeciesReference
stoichiometry: 3.0
species: 168581

184062
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Inorganic triphosphate_HO10P3

178569
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate II (core 2-linked), degradation product 2_C70H114N5O56S2X

164510
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Acetoacetate_C4H5O3

171644
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: dTMP_C10H13N2O8P

176914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: heparan sulfate, precursor 7_C73H109N4O58X

952363
type: Reaction
is: ENSMUSG00000027301.5
reactant: 255404
product: 255440
notes: R_DASPO1p subsystem: Alanine and Aspartate Metabolism R_DASPO1p equation: [x] : asp-D + h2o + o2 --> h2o2 + nh4 + oaa
reversible: false
fast: false
product: 255428
product: 255416
is: http://identifiers.org/ec-code/1.4.3.1
name: D-aspartate oxidase, peroxisomal
reactant: 255357
reactant: 255370

255404
type: SpeciesReference
stoichiometry: 1.0
species: 166856

166856
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: D-Aspartate_C4H6NO4

255440
type: SpeciesReference
stoichiometry: 1.0
species: 181813

181813
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Ammonium_H4N

255428
type: SpeciesReference
stoichiometry: 1.0
species: 175602

255416
type: SpeciesReference
stoichiometry: 1.0
species: 182310

182310
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Oxaloacetate_C4H2O5

255357
type: SpeciesReference
stoichiometry: 1.0
species: 175698

255370
type: SpeciesReference
stoichiometry: 1.0
species: 182214

184326
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Proline_C5H9NO2

945493
type: Reaction
name: _4-aminobutyrate reversible transport in via sodium symport (1:2)
fast: false
notes: R_ABUTt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_ABUTt4_LPAREN_2_RPAREN_r equation: _4abut[e] + (2) na1[e] <==> 4abut[c] + (2) na1[c]
is: ENSMUSG00000030108.7
reactant: 192230
product: 192254
is: ENSMUSG00000030307.7
is: ENSMUSG00000030310.6
reversible: true
reactant: 192218
product: 192242

192230
type: SpeciesReference
stoichiometry: 2.0
species: 181389

192254
type: SpeciesReference
stoichiometry: 2.0
species: 181377

192218
type: SpeciesReference
stoichiometry: 1.0
species: 162459

162459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: _4-Aminobutanoate_C4H9NO2

192242
type: SpeciesReference
stoichiometry: 1.0
species: 162446

162446
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-Aminobutanoate_C4H9NO2

955619
type: Reaction
product: 289181
product: 289205
product: 289157
reactant: 289097
notes: R_ADNt4 subsystem: Transport, Extracellular R_ADNt4 equation: adn[e] + na1[e] --> adn[c] + na1[c] R_URIt4 subsystem: Transport, Extracellular R_URIt4 equation: na1[e] + uri[e] --> na1[c] + uri[c] R_INSt4 subsystem: Transport, Extracellular R_INSt4 equation: ins[e] + na1[e] --> ins[c] + na1[c] R_GSNt4 subsystem: Transport, Extracellular R_GSNt4 equation: gsn[e] + na1[e] --> gsn[c] + na1[c]
fast: false
reactant: 289133
product: 289193
reversible: false
reactant: 289145
reactant: 289121
is: ENSMUSG00000027219.4
product: 289169
is: ENSMUSG00000079071.1
reactant: 289109

289181
type: SpeciesReference
stoichiometry: 1.0
species: 165321

165321
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Adenosine_C10H13N5O4

289205
type: SpeciesReference
stoichiometry: 1.0
species: 188032

289157
type: SpeciesReference
stoichiometry: 4.0
species: 181377

289097
type: SpeciesReference
stoichiometry: 4.0
species: 181389

289133
type: SpeciesReference
stoichiometry: 1.0
species: 175224

175224
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Guanosine_C10H13N5O5

289193
type: SpeciesReference
stoichiometry: 1.0
species: 177373

177373
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Inosine_C10H12N4O5

289145
type: SpeciesReference
stoichiometry: 1.0
species: 177385

177385
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Inosine_C10H12N4O5

289121
type: SpeciesReference
stoichiometry: 1.0
species: 165334

165334
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Adenosine_C10H13N5O4

289169
type: SpeciesReference
stoichiometry: 1.0
species: 175210

175210
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Guanosine_C10H13N5O5

289109
type: SpeciesReference
stoichiometry: 1.0
species: 188044

188044
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Uridine_C9H12N2O6

946554
type: Reaction
reactant: 201311
notes: R_DMGDHm subsystem: Glycine, Serine, and Threonine Metabolism R_DMGDHm equation: [m] : dmgly + fad + h2o --> fadh2 + fald + sarcs
name: dimethylglycine dehydrogenase, mitochondrial
reactant: 201335
reversible: false
product: 201347
reactant: 201323
is: ENSMUSG00000042102.5
product: 201359
fast: false
is: http://identifiers.org/ec-code/1.5.99.2
product: 201371

201311
type: SpeciesReference
stoichiometry: 1.0
species: 171123

201335
type: SpeciesReference
stoichiometry: 1.0
species: 172499

201347
type: SpeciesReference
stoichiometry: 1.0
species: 172547

201323
type: SpeciesReference
stoichiometry: 1.0
species: 175662

201359
type: SpeciesReference
stoichiometry: 1.0
species: 185325

185325
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Sarcosine_C3H7NO2

201371
type: SpeciesReference
stoichiometry: 1.0
species: 172608

172608
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Formaldehyde_CH2O

952639
type: Reaction
modifier: 259391
is: http://identifiers.org/ec-code/2.1.2.1
modifier: 259415
notes: R_GHMT2rm subsystem: Glycine, Serine, and Threonine Metabolism R_GHMT2rm equation: [m] : ser-L + thf <==> gly + h2o + mlthf R_GHMT3m subsystem: Lysine Metabolism R_GHMT3m equation: [m] : 3htmelys + h --> 4tmeabut + gly
product: 259379
reversible: false
modifier: 259427
modifier: 259403
product: 259367
reactant: 259343
fast: false
is: ENSMUSG00000025403.2
reactant: 259355
modifier: 259440

259379
type: SpeciesReference
stoichiometry: 1.0
species: 174661

174661
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Glycine_C2H5NO2

185556
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Serine_C3H7NO3

259367
type: SpeciesReference
stoichiometry: 1.0
species: 162823

162823
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _4-Trimethylammoniobutanal_C7H16NO

259343
type: SpeciesReference
stoichiometry: 1.0
species: 161975

259355
type: SpeciesReference
stoichiometry: 1.0
species: 175770

181066
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _5,10-Methylenetetrahydrofolate_C20H21N7O6

954862
type: Reaction
reversible: false
notes: R_M1316Mg subsystem: N-Glycan Biosynthesis R_M1316Mg equation: [g] : (2) h2o + nm4masn --> (2) man + nm2masn
is: ENSMUSG00000024085.6
product: 279891
is: http://identifiers.org/ec-code/3.2.1.114
reactant: 279867
fast: false
name: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
reactant: 279879
is: ENSMUSG00000038886.7
product: 279903

279891
type: SpeciesReference
stoichiometry: 1.0
species: 181885

279867
type: SpeciesReference
stoichiometry: 2.0
species: 175638

175638
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: H2O_H2O

279879
type: SpeciesReference
stoichiometry: 1.0
species: 181897

181897
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C54H90N3O40X

279903
type: SpeciesReference
stoichiometry: 2.0
species: 180536

180536
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: D-Mannose_C6H12O6

169019
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 5_C23H36O24S

954622
type: Reaction
product: 278545
reactant: 278207
fast: false
reactant: 278027
reactant: 277979
reactant: 278268
product: 278412
reactant: 278256
reactant: 278292
product: 278472
product: 278424
product: 278521
reactant: 278075
product: 278484
product: 278581
reactant: 278195
reactant: 278015
reactant: 278135
reactant: 278328
reactant: 278364
reactant: 278232
product: 278400
product: 278388
product: 278460
reactant: 278352
reactant: 278220
reactant: 278183
product: 278448
is: http://identifiers.org/ec-code/1.3.99.12
product: 278497
reactant: 278099
reactant: 278123
reactant: 277991
reactant: 278063
is: http://identifiers.org/ec-code/1.3.99.2
reactant: 278003
reactant: 278039
reactant: 278159
product: 278557
notes: R_FAOXC183806m subsystem: Fatty acid oxidation R_FAOXC183806m equation: [m] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC161802m subsystem: Fatty acid activation R_FAOXC161802m equation: [m] : (4) coa + (3) fad + (4) h2o + hdd2coa + (4) nad --> (4) accoa + (3) fadh2 + (4) h + (4) nadh + occoa R_FAOXC160 subsystem: Fatty acid oxidation R_FAOXC160 equation: [m] : (7) coa + (7) fad + (7) h2o + (7) nad + pmtcoa --> (8) accoa + (7) fadh2 + (7) h + (7) nadh R_FAOXC2031836m subsystem: Fatty acid oxidation R_FAOXC2031836m equation: [m] : coa + dlnlcgcoa + fad + h2o + nad --> accoa + fadh2 + h + lnlncgcoa + nadh R_FAOXC80 subsystem: Fatty acid oxidation R_FAOXC80 equation: [m] : (3) coa + (3) fad + (3) h2o + (3) nad + occoa --> (4) accoa + (3) fadh2 + (3) h + (3) nadh R_FAOXC170m subsystem: Fatty acid oxidation R_FAOXC170m equation: [m] : (7) coa + (7) fad + (7) h2o + hpdcacoa + (7) nad --> (7) accoa + (7) fadh2 + (7) h + (7) nadh + ppcoa R_FAOXC11 subsystem: Fatty acid oxidation R_FAOXC11 equation: [m] : coa + dmnoncoa + h2o + nad --> accoa + dmhptcoa + h + nadh R_PPCOAOm subsystem: Propanoate Metabolism R_PPCOAOm equation: [m] : fad + ppcoa --> fadh2 + prpncoa R_FAOXC2251836m subsystem: Fatty acid oxidation R_FAOXC2251836m equation: [m] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_FAOXC18280m subsystem: Fatty acid oxidation R_FAOXC18280m equation: [m] : (5) coa + (3) fad + (5) h2o + lneldccoa + (5) nad --> (5) accoa + (3) fadh2 + (5) h + (5) nadh + occoa R_FAOXC16180m subsystem: Fatty acid oxidation R_FAOXC16180m equation: [m] : (4) coa + (3) fad + (4) h2o + hdcoa + (4) nad --> (4) accoa + (3) fadh2 + (4) h + (4) nadh + occoa R_FAOXC2051843m subsystem: Fatty acid oxidation R_FAOXC2051843m equation: [m] : coa + h2o + nad + tmndnccoa --> accoa + h + nadh + strdnccoa R_FAOXC183803m subsystem: Fatty acid oxidation R_FAOXC183803m equation: [m] : (5) coa + (2) fad + (5) …
is: ENSMUSG00000062908.5
is: http://identifiers.org/ec-code/1.3.99.3
product: 278569
product: 278509
reactant: 278051
reactant: 278171
reactant: 278376
reactant: 278244
reactant: 278280
reactant: 278087
reactant: 278316
reactant: 278147
reactant: 278111
reactant: 278304
reversible: false
product: 278436
product: 278533
reactant: 278340
product: 278593

278545
type: SpeciesReference
stoichiometry: 2.0
species: 183892

278207
type: SpeciesReference
stoichiometry: 1.0
species: 179546

179546
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: linoelaidyl coenzyme A_C39H62N7O17P3S

278027
type: SpeciesReference
stoichiometry: 1.0
species: 171063

171063
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: dihomo-gamma-linolenyl coenzyme A_C41H64N7O17P3S

277979
type: SpeciesReference
stoichiometry: 1.0
species: 185933

185933
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S

278268
type: SpeciesReference
stoichiometry: 1.0
species: 183892

278412
type: SpeciesReference
stoichiometry: 1.0
species: 183760

183760
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S

278256
type: SpeciesReference
stoichiometry: 1.0
species: 179606

179606
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: linoleic coenzyme A_C39H62N7O17P3S

278292
type: SpeciesReference
stoichiometry: 111.0
species: 168545

278472
type: SpeciesReference
stoichiometry: 11.0
species: 182382

182382
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Octanoyl-CoA (n-C8:0CoA)_C29H46N7O17P3S

278424
type: SpeciesReference
stoichiometry: 78.0
species: 172547

278521
type: SpeciesReference
stoichiometry: 3.0
species: 175578

175578
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Hydrogen peroxide_H2O2

278075
type: SpeciesReference
stoichiometry: 1.0
species: 172005

172005
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: eicosatetranoyl coenzyme A_C41H62N7O17P3S

278484
type: SpeciesReference
stoichiometry: 1.0
species: 166976

278581
type: SpeciesReference
stoichiometry: 1.0
species: 171135

171135
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _2,6 dimethylheptanoyl-CoA_C30H52N7O17P3S

278195
type: SpeciesReference
stoichiometry: 1.0
species: 176060

176060
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574

278015
type: SpeciesReference
stoichiometry: 2.0
species: 183760

278135
type: SpeciesReference
stoichiometry: 2.0
species: 167387

167387
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: cervonyl coenzyme A_C43H62N7O17P3S

278328
type: SpeciesReference
stoichiometry: 2.0
species: 170133

170133
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: docosa-4,7,10,13,16-pentaenoyl coenzyme A_C43H64N7O17P3S

278364
type: SpeciesReference
stoichiometry: 111.0
species: 181461

181461
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

278232
type: SpeciesReference
stoichiometry: 1.0
species: 184663

184663
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: pentadecanoyl Coenzyme A_C36H60N7O17P3S

278400
type: SpeciesReference
stoichiometry: 1.0
species: 166664

166664
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: C20:4-CoA_C41H62N7O17P3S

278388
type: SpeciesReference
stoichiometry: 1.0
species: 185933

278460
type: SpeciesReference
stoichiometry: 1.0
species: 184555

278352
type: SpeciesReference
stoichiometry: 78.0
species: 172499

278220
type: SpeciesReference
stoichiometry: 1.0
species: 187107

187107
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: timnodonyl coenzyme A_C41H60N7O17P3S

278183
type: SpeciesReference
stoichiometry: 1.0
species: 167266

167266
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Butanoyl-CoA_C25H38N7O17P3S

278448
type: SpeciesReference
stoichiometry: 2.0
species: 186029

186029
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: stearidonyl coenzyme A_C39H58N7O17P3S

278497
type: SpeciesReference
stoichiometry: 1.0
species: 161465

161465
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574

278099
type: SpeciesReference
stoichiometry: 1.0
species: 161441

161441
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _2-Methylbutanoyl-CoA_C26H40N7O17P3S

278123
type: SpeciesReference
stoichiometry: 1.0
species: 182382

277991
type: SpeciesReference
stoichiometry: 1.0
species: 166664

278063
type: SpeciesReference
stoichiometry: 1.0
species: 186029

278003
type: SpeciesReference
stoichiometry: 1.0
species: 182527

182527
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574

278039
type: SpeciesReference
stoichiometry: 1.0
species: 176036

176036
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Hexadecenoyl-CoA (n-C16:1CoA)_C37H60N7O17P3S

278159
type: SpeciesReference
stoichiometry: 1.0
species: 182551

182551
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Octadecenoyl-CoA (n-C18:1CoA)_C39H64N7O17P3S

278557
type: SpeciesReference
stoichiometry: 2.0
species: 179727

179727
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: gamma-linolenoyl-CoA_C39H60N7O17P3S

278569
type: SpeciesReference
stoichiometry: 111.0
species: 175770

278509
type: SpeciesReference
stoichiometry: 116.0
species: 164607

164607
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Acetyl-CoA_C23H34N7O17P3S

278051
type: SpeciesReference
stoichiometry: 111.0
species: 175662

278171
type: SpeciesReference
stoichiometry: 1.0
species: 171160

171160
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S

278376
type: SpeciesReference
stoichiometry: 3.0
species: 182178

278244
type: SpeciesReference
stoichiometry: 1.0
species: 188164

188164
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: vaccenyl coenzyme A_C39H64N7O17P3S

278280
type: SpeciesReference
stoichiometry: 1.0
species: 176397

176397
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: heptadecanoyl coa_C38H64N7O17P3S

278087
type: SpeciesReference
stoichiometry: 1.0
species: 166567

166567
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: arachidyl coenzyme A_C41H70N7O17P3S

278316
type: SpeciesReference
stoichiometry: 1.0
species: 186381

186381
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Tetradecanoyl-CoA (n-C14:0CoA)_C35H58N7O17P3S

278147
type: SpeciesReference
stoichiometry: 1.0
species: 179666

278111
type: SpeciesReference
stoichiometry: 1.0
species: 165581

165581
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: adrenyl coenzyme A_C43H66N7O17P3S

278304
type: SpeciesReference
stoichiometry: 1.0
species: 177071

278436
type: SpeciesReference
stoichiometry: 1.0
species: 161429

161429
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574

278533
type: SpeciesReference
stoichiometry: 2.0
species: 187107

278340
type: SpeciesReference
stoichiometry: 1.0
species: 179727

278593
type: SpeciesReference
stoichiometry: 111.0
species: 181522

181522
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

169829
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Deoxyadenosine_C10H13N5O3

172800
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Formate_CH1O2

169285
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 6_C23H35O27S2

173401
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1900H3128N20O720P20

953973
type: Reaction
reactant: 271714
reactant: 271678
reactant: 271702
notes: R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD20x subsystem: Tryptophan metabolism R_ALDD20x equation: [c] : h2o + id3acald + nad --> (2) h + ind3ac + nadh R_BAMPPALDOX subsystem: beta-Alanine metabolism R_BAMPPALDOX equation: [c] : bamppald + h2o + nad --> ala-B + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_IMACTD subsystem: Histidine Metabolism R_IMACTD equation: [c] : h2o + im4act + nad --> (2) h + im4ac + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_PYLALDOX subsystem: Limonene and pinene degradation R_PYLALDOX equation: [c] : h2o + nad + pylald --> (2) h + nadh + peracd R_NABTNO subsystem: Arginine and Proline Metabolism R_NABTNO equation: [c] : h2o + n4abutn + nad --> 4aabutn + (2) h + nadh R_5HOXINDACTOX subsystem: Tryptophan metabolism R_5HOXINDACTOX equation: [c] : 5hoxindact + h2o + nad --> 5hoxindoa + (2) h + nadh R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh
is: http://identifiers.org/ec-code/1.2.1.21
fast: false
product: 271750
reversible: false
product: 271882
reactant: 271642
reactant: 271581
reactant: 271606
reactant: 271594
product: 271834
product: 271870
reactant: 271654
is: http://identifiers.org/ec-code/1.2.1.3
product: 271822
product: 271810
reactant: 271630
product: 271738
product: 271798
product: 271786
reactant: 271726
product: 271858
is: ENSMUSG00000053279.5
is: ENSMUSG00000024747.2
product: 271774
product: 271762
product: 271846
reactant: 271666
reactant: 271618
reactant: 271690

271714
type: SpeciesReference
stoichiometry: 1.0
species: 174250

271678
type: SpeciesReference
stoichiometry: 1.0
species: 163136

271702
type: SpeciesReference
stoichiometry: 12.0
species: 175614

271750
type: SpeciesReference
stoichiometry: 1.0
species: 174805

271882
type: SpeciesReference
stoichiometry: 11.0
species: 181510

271642
type: SpeciesReference
stoichiometry: 1.0
species: 173947

271581
type: SpeciesReference
stoichiometry: 1.0
species: 179146

271606
type: SpeciesReference
stoichiometry: 1.0
species: 177277

271594
type: SpeciesReference
stoichiometry: 1.0
species: 181340

271834
type: SpeciesReference
stoichiometry: 1.0
species: 183410

183410
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Perillic acid_C10H13O2

271870
type: SpeciesReference
stoichiometry: 23.0
species: 175722

271654
type: SpeciesReference
stoichiometry: 1.0
species: 164534

271822
type: SpeciesReference
stoichiometry: 1.0
species: 179086

271810
type: SpeciesReference
stoichiometry: 1.0
species: 163161

163161
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-Hydroxyindoleacetate_C10H8NO3

271630
type: SpeciesReference
stoichiometry: 11.0
species: 181437

271738
type: SpeciesReference
stoichiometry: 1.0
species: 177253

177253
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Imidazole-4-acetate_C5H5N2O2

271798
type: SpeciesReference
stoichiometry: 1.0
species: 174334

271786
type: SpeciesReference
stoichiometry: 1.0
species: 162422

162422
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-Acetamidobutanoate_C6H10NO3

271726
type: SpeciesReference
stoichiometry: 1.0
species: 179122

271858
type: SpeciesReference
stoichiometry: 1.0
species: 179050

271774
type: SpeciesReference
stoichiometry: 1.0
species: 164438

271762
type: SpeciesReference
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species: 177325

177325
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Indole-3-acetate_C10H8NO2

271846
type: SpeciesReference
stoichiometry: 1.0
species: 165931

165931
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: beta-Alanine_C3H7NO2

271666
type: SpeciesReference
stoichiometry: 1.0
species: 167001

271618
type: SpeciesReference
stoichiometry: 1.0
species: 184795

184795
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Perillyl aldehyde_C10H14O

271690
type: SpeciesReference
stoichiometry: 1.0
species: 177119

167327
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Butyrate (n-C4:0)_C4H7O2

164498
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Acetoacetate_C4H5O3

955547
type: Reaction
reactant: 288590
reactant: 288578
reactant: 288566
reversible: true
is: ENSMUSG00000039450.4
is: http://identifiers.org/ec-code/1.1.1.10
product: 288602
fast: false
name: xylulose reductase
product: 288614
notes: R_XYLUR subsystem: Pentose and Glucuronate Interconversions R_XYLUR equation: [c] : h + nadph + xylu-L <==> nadp + xylt
is: ENSMUSG00000025150.2

288590
type: SpeciesReference
stoichiometry: 1.0
species: 181631

288578
type: SpeciesReference
stoichiometry: 1.0
species: 175722

288566
type: SpeciesReference
stoichiometry: 1.0
species: 188766

188766
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Xylulose_C5H10O5

288602
type: SpeciesReference
stoichiometry: 1.0
species: 181558

288614
type: SpeciesReference
stoichiometry: 1.0
species: 188742

188742
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Xylitol_C5H12O5

950246
type: Reaction
is: http://identifiers.org/ec-code/4.1.1.41
reactant: 236003
is: http://identifiers.org/ec-code/4.1.1.9
reactant: 236016
reactant: 235979
reactant: 235991
notes: R_MMCDm subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMCDm equation: [m] : h + mmcoa-S --> co2 + ppcoa R_MMCDp subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMCDp equation: [x] : h + mmcoa-S --> co2 + ppcoa R_MMCD subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMCD equation: [c] : h + mmcoa-S --> co2 + ppcoa R_MCDp subsystem: Fatty Acid Metabolism R_MCDp equation: [x] : h + malcoa --> accoa + co2 R_MCD subsystem: Fatty Acid Metabolism R_MCD equation: [c] : h + malcoa --> accoa + co2 R_MCDm subsystem: Fatty Acid Metabolism R_MCDm equation: [m] : h + malcoa --> accoa + co2
reactant: 235942
reactant: 236028
product: 236112
fast: false
reactant: 236040
reversible: false
product: 236100
product: 236149
product: 236088
product: 236137
product: 236125
product: 236076
is: ENSMUSG00000074064.3
product: 236064
reactant: 235955
product: 236052
reactant: 235966

236003
type: SpeciesReference
stoichiometry: 2.0
species: 175806

236016
type: SpeciesReference
stoichiometry: 1.0
species: 181126

181126
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: (S)-Methylmalonyl-CoA_C25H35N7O19P3S

235979
type: SpeciesReference
stoichiometry: 1.0
species: 180403

235991
type: SpeciesReference
stoichiometry: 1.0
species: 180379

180379
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Malonyl-CoA_C24H33N7O19P3S

235942
type: SpeciesReference
stoichiometry: 1.0
species: 181102

181102
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: (S)-Methylmalonyl-CoA_C25H35N7O19P3S

236028
type: SpeciesReference
stoichiometry: 2.0
species: 175722

236112
type: SpeciesReference
stoichiometry: 1.0
species: 183880

183880
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Propanoyl-CoA_C24H36N7O17P3S

236040
type: SpeciesReference
stoichiometry: 2.0
species: 175770

236100
type: SpeciesReference
stoichiometry: 1.0
species: 183892

236149
type: SpeciesReference
stoichiometry: 1.0
species: 164643

236088
type: SpeciesReference
stoichiometry: 1.0
species: 164607

236137
type: SpeciesReference
stoichiometry: 1.0
species: 164583

164583
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Acetyl-CoA_C23H34N7O17P3S

236125
type: SpeciesReference
stoichiometry: 2.0
species: 168436

236076
type: SpeciesReference
stoichiometry: 1.0
species: 183905

236064
type: SpeciesReference
stoichiometry: 2.0
species: 168461

235955
type: SpeciesReference
stoichiometry: 1.0
species: 181114

236052
type: SpeciesReference
stoichiometry: 2.0
species: 168485

168485
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: CO2_CO2

235966
type: SpeciesReference
stoichiometry: 1.0
species: 180391

180391
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Malonyl-CoA_C24H33N7O19P3S

168412
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514

187717
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: UDPglucose_C15H22N2O17P2

176806
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: heparan sulfate, precursor 13_C79H116N5O92S9X

954790
type: Reaction
product: 279502
reactant: 279490
notes: R_ALAR subsystem: Alanine and Aspartate Metabolism R_ALAR equation: [c] : ala-L <==> ala-D
is: ENSMUSG00000031485.7
is: http://identifiers.org/ec-code/5.1.1.1
fast: false
reversible: true
name: alanine racemase

279502
type: SpeciesReference
stoichiometry: 1.0
species: 165967

165967
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Alanine_C3H7NO2

279490
type: SpeciesReference
stoichiometry: 1.0
species: 166015

166015
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Alanine_C3H7NO2

954429
type: Reaction
reversible: true
reactant: 276481
is: ENSMUSG00000020100.6
product: 276566
reactant: 276433
notes: R_GSNtl subsystem: Transport, Lysosomal R_GSNtl equation: gsn[l] <==> gsn[c] R_ADEtl subsystem: Transport, Lysosomal R_ADEtl equation: ade[l] <==> ade[c] R_INStl subsystem: Transport, Lysosomal R_INStl equation: ins[l] <==> ins[c] R_Uritl subsystem: Transport, Lysosomal R_Uritl equation: uri[l] <==> uri[c] R_THYMDtl subsystem: Transport, Lysosomal R_THYMDtl equation: thymd[l] <==> thymd[c] R_HXANtl subsystem: Transport, Lysosomal R_HXANtl equation: hxan[l] <==> hxan[c] R_CYTDtl subsystem: Transport, Lysosomal R_CYTDtl equation: cytd[l] <==> cytd[c] R_ADNtl subsystem: Transport, Lysosomal R_ADNtl equation: adn[l] <==> adn[c]
reactant: 276493
product: 276542
fast: false
product: 276578
reactant: 276408
product: 276590
product: 276505
product: 276518
reactant: 276420
product: 276554
reactant: 276445
product: 276530
reactant: 276469
reactant: 276457

276481
type: SpeciesReference
stoichiometry: 1.0
species: 187008

187008
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Thymidine_C10H14N2O5

276566
type: SpeciesReference
stoichiometry: 1.0
species: 165321

276433
type: SpeciesReference
stoichiometry: 1.0
species: 169768

169768
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Cytidine_C9H13N3O5

276493
type: SpeciesReference
stoichiometry: 1.0
species: 177397

177397
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Inosine_C10H12N4O5

276542
type: SpeciesReference
stoichiometry: 1.0
species: 165259

165259
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Adenine_C5H5N5

276578
type: SpeciesReference
stoichiometry: 1.0
species: 177373

276408
type: SpeciesReference
stoichiometry: 1.0
species: 176999

176999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Hypoxanthine_C5H4N4O

276590
type: SpeciesReference
stoichiometry: 1.0
species: 188032

276505
type: SpeciesReference
stoichiometry: 1.0
species: 176975

176975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Hypoxanthine_C5H4N4O

276518
type: SpeciesReference
stoichiometry: 1.0
species: 169743

276420
type: SpeciesReference
stoichiometry: 1.0
species: 188056

188056
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Uridine_C9H12N2O6

276554
type: SpeciesReference
stoichiometry: 1.0
species: 175210

276445
type: SpeciesReference
stoichiometry: 1.0
species: 175237

276530
type: SpeciesReference
stoichiometry: 1.0
species: 186984

276469
type: SpeciesReference
stoichiometry: 1.0
species: 165283

165283
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Adenine_C5H5N5

276457
type: SpeciesReference
stoichiometry: 1.0
species: 165347

165347
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Adenosine_C10H13N5O4

174588
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Glyoxylate_C2H1O3

168352
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: CMP_C9H12N3O8P

165124
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: N-Acetylneuraminate_C11H18NO9

174938
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GM1b (homo sapiens)_C55H95N3O30FULLRCO

955897
type: Reaction
notes: R_PRDXl subsystem: Miscellaneous R_PRDXl equation: [l] : h2o2 + meoh --> fald + (2) h2o
reversible: false
product: 291666
reactant: 291630
name: Peroxidase (multiple substrates)
reactant: 291642
is: http://identifiers.org/ec-code/1.11.1.7
is: ENSMUSG00000009350.4
fast: false
product: 291654

291666
type: SpeciesReference
stoichiometry: 2.0
species: 175650

291630
type: SpeciesReference
stoichiometry: 1.0
species: 175566

175566
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Hydrogen peroxide_H2O2

291642
type: SpeciesReference
stoichiometry: 1.0
species: 180644

180644
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Methanol_CH4O1

291654
type: SpeciesReference
stoichiometry: 1.0
species: 172596

172596
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Formaldehyde_CH2O

179980
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: trimannosyl-glucosaminyl-acylphosphatidylinositol (H4)_C49H88NO29PFULLRCO2FULLR2CO2

164836
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Acetyl-D-glucosamine 1-phosphate_C8H14NO9P

953241
type: Reaction
fast: false
notes: R_CHOLATEt3 subsystem: Transport, Extracellular R_CHOLATEt3 equation: atp[c] + cholate[c] + h2o[c] --> adp[c] + cholate[e] + h[c] + pi[c] R_TCHOLAt3 subsystem: Transport, Extracellular R_TCHOLAt3 equation: atp[c] + h2o[c] + tchola[c] --> adp[c] + h[c] + pi[c] + tchola[e] R_GCHOLAt3 subsystem: Transport, Extracellular R_GCHOLAt3 equation: atp[c] + gchola[c] + h2o[c] --> adp[c] + gchola[e] + h[c] + pi[c]
product: 265316
product: 265366
is: ENSMUSG00000027048.7
product: 265328
reversible: false
product: 265378
reactant: 265304
product: 265353
product: 265341
reactant: 265292
reactant: 265280
reactant: 265256
reactant: 265268

265316
type: SpeciesReference
stoichiometry: 1.0
species: 186308

265366
type: SpeciesReference
stoichiometry: 1.0
species: 167881

167881
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Cholate_C24H39O5

265328
type: SpeciesReference
stoichiometry: 3.0
species: 183652

265378
type: SpeciesReference
stoichiometry: 3.0
species: 175722

265304
type: SpeciesReference
stoichiometry: 3.0
species: 175614

265353
type: SpeciesReference
stoichiometry: 3.0
species: 165387

265341
type: SpeciesReference
stoichiometry: 1.0
species: 173984

173984
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: glycocholate_C26H43NO6

265292
type: SpeciesReference
stoichiometry: 1.0
species: 167869

167869
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Cholate_C24H39O5

265280
type: SpeciesReference
stoichiometry: 1.0
species: 173972

265256
type: SpeciesReference
stoichiometry: 3.0
species: 166904

265268
type: SpeciesReference
stoichiometry: 1.0
species: 186296

186296
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: taurocholic acid_C26H45NO7S

946180
type: Reaction
reversible: false
notes: R_O16G1e subsystem: Starch and Sucrose Metabolism R_O16G1e equation: [e] : glygn4 + h2o --> glc-D + glygn5 R_SUCRe subsystem: Galactose metabolism R_SUCRe equation: [e] : h2o + sucr --> fru + glc-D R_O16G2e subsystem: Starch and Sucrose Metabolism R_O16G2e equation: [e] : h2o + strch2 --> glc-D + malt
product: 197856
reactant: 197819
is: http://identifiers.org/ec-code/3.2.1.26
reactant: 197807
product: 197868
fast: false
reactant: 197794
product: 197880
is: http://identifiers.org/ec-code/3.2.1.10
product: 197844
is: ENSMUSG00000027790.7
reactant: 197831

197856
type: SpeciesReference
stoichiometry: 1.0
species: 172944

172944
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: D-Fructose_C6H12O6

197819
type: SpeciesReference
stoichiometry: 1.0
species: 174889

174889
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: glycogen, structure 4 (glycogenin-1,6-{2[1,4-Glc], [1,4-Glc]})_C18H31O16X

197807
type: SpeciesReference
stoichiometry: 1.0
species: 186150

186150
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Sucrose_C12H22O11

197868
type: SpeciesReference
stoichiometry: 1.0
species: 180427

180427
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Maltose_C12H22O11

197794
type: SpeciesReference
stoichiometry: 1.0
species: 185993

185993
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: starch, structure 2 (1,6-{2[1,4-Glc], [1,4-Glc]})_C18H32O16

197880
type: SpeciesReference
stoichiometry: 3.0
species: 174286

197844
type: SpeciesReference
stoichiometry: 1.0
species: 174901

174901
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: glycogen, structure 5 (glycogenin-2[1,4-Glc])_C12H21O11X

197831
type: SpeciesReference
stoichiometry: 3.0
species: 175626

172149
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Estradiol_C18H24O2

169503
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5b_C45H64N2O51S5X

953349
type: Reaction
is: ENSMUSG00000007107.4
product: 266391
reversible: false
name: Na+/K+ exchanging ATPase
is: http://identifiers.org/ec-code/3.6.3.9
fast: false
reactant: 266307
product: 266403
is: ENSMUSG00000040907.8
reactant: 266343
product: 266379
is: ENSMUSG00000016327.2
is: ENSMUSG00000032412.5
notes: R_NaKt subsystem: Transport, Extracellular R_NaKt equation: atp[c] + h2o[c] + (2) k[e] + (3) na1[c] --> adp[c] + h[c] + (2) k[c] + (3) na1[e] + pi[c]
reactant: 266331
reactant: 266319
product: 266367
product: 266355
is: ENSMUSG00000041329.5
is: ENSMUSG00000007097.7
is: ENSMUSG00000033161.6
is: ENSMUSG00000026576.7

266391
type: SpeciesReference
stoichiometry: 1.0
species: 165387

266307
type: SpeciesReference
stoichiometry: 2.0
species: 177543

266403
type: SpeciesReference
stoichiometry: 1.0
species: 175722

266343
type: SpeciesReference
stoichiometry: 1.0
species: 175614

266379
type: SpeciesReference
stoichiometry: 3.0
species: 181389

266331
type: SpeciesReference
stoichiometry: 3.0
species: 181377

266319
type: SpeciesReference
stoichiometry: 1.0
species: 166904

266367
type: SpeciesReference
stoichiometry: 1.0
species: 183652

266355
type: SpeciesReference
stoichiometry: 2.0
species: 177531

187863
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: UMP_C9H11N2O9P

949319
type: Reaction
notes: R_ACOAD8m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ACOAD8m equation: [m] : fad + ivcoa --> 3mb2coa + fadh2
product: 225765
is: ENSMUSG00000079912.1
name: acyl-CoA dehydrogenase (isovaleryl-CoA), mitochondrial
fast: false
product: 225777
reactant: 225753
is: http://identifiers.org/ec-code/1.3.99.10
reversible: false
reactant: 225741
is: ENSMUSG00000020635.6

225765
type: SpeciesReference
stoichiometry: 1.0
species: 162023

225777
type: SpeciesReference
stoichiometry: 1.0
species: 172547

225753
type: SpeciesReference
stoichiometry: 1.0
species: 172499

225741
type: SpeciesReference
stoichiometry: 1.0
species: 177519

177519
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Isovaleryl-CoA_C26H40N7O17P3S

178232
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 19_C171H275N12O137S5X

175325
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: GT3 (homo sapiens)_C63H104N4O36FULLRCO

188008
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Urea_CH4N2O

170290
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Dodecanoate (n-C12:0)_C12H23O2

161258
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: (2-Aminoethyl)phosphonate_C2H7NO3P

172776
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Folate_C19H18N7O6

181922
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: NMN_C11H14N2O8P

176180
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: hexacosanoyl carnitine_C33H65NO4

166724
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Arginine_C6H15N4O2

951473
type: Reaction
is: ENSMUSG00000027984.7
product: 246264
reactant: 246252
product: 246276
fast: false
reactant: 246228
notes: R_HACD1m subsystem: Tryptophan metabolism R_HACD1m equation: [m] : aacoa + h + nadh <==> 3hbcoa + nad
is: http://identifiers.org/ec-code/1.1.1.35
reversible: true
name: _3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA) (mitochondria)
reactant: 246240

246264
type: SpeciesReference
stoichiometry: 1.0
species: 161855

246252
type: SpeciesReference
stoichiometry: 1.0
species: 181522

246276
type: SpeciesReference
stoichiometry: 1.0
species: 181461

246228
type: SpeciesReference
stoichiometry: 1.0
species: 164378

164378
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Acetoacetyl-CoA_C25H36N7O18P3S

246240
type: SpeciesReference
stoichiometry: 1.0
species: 175770

162242
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Phospho-D-glycerate_C3H4O7P

950414
type: Reaction
notes: R_IDHPOXOXb subsystem: Tyrosine metabolism R_IDHPOXOXb equation: [c] : iodine + tyr-L --> 3ityr-L + h + i R_IDHPOXOX2b subsystem: Tyrosine metabolism R_IDHPOXOX2b equation: [c] : 3ityr-L + iodine --> 35diotyr + h + i R_IDHPOXOX3 subsystem: Tyrosine metabolism R_IDHPOXOX3 equation: [c] : 35diotyr + 3ityr-L + h2o2 --> 2amac + (2) h2o + triodthy R_IDHPOXOX4 subsystem: Tyrosine metabolism R_IDHPOXOX4 equation: [c] : (2) 35diotyr + h2o2 --> 2amac + (2) h2o + thyox-L R_THYPX subsystem: Tyrosine metabolism R_THYPX equation: [c] : (2) h + h2o2 + (2) i --> (2) h2o + iodine
product: 237309
product: 237221
reactant: 237195
reactant: 237182
reactant: 237143
product: 237234
product: 237321
is: ENSMUSG00000020673.7
reactant: 237168
reversible: false
reactant: 237131
reactant: 237155
product: 237247
reactant: 237208
product: 237272
product: 237297
product: 237285
product: 237260
fast: false
is: http://identifiers.org/ec-code/1.11.1.8

237309
type: SpeciesReference
stoichiometry: 6.0
species: 175614

237221
type: SpeciesReference
stoichiometry: 1.0
species: 161999

161999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Iodo-L-tyrosine_C9H10INO3

237195
type: SpeciesReference
stoichiometry: 2.0
species: 177047

177047
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Iodide_I

237182
type: SpeciesReference
stoichiometry: 3.0
species: 175542

237143
type: SpeciesReference
stoichiometry: 3.0
species: 161709

161709
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3,5-Diiodo-L-tyrosine_C9H9I2NO3

237234
type: SpeciesReference
stoichiometry: 2.0
species: 161246

161246
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _2-Aminoacrylate_C3H5NO2

237321
type: SpeciesReference
stoichiometry: 2.0
species: 175722

237168
type: SpeciesReference
stoichiometry: 1.0
species: 187524

187524
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Tyrosine_C9H11NO3

237131
type: SpeciesReference
stoichiometry: 2.0
species: 161999

237155
type: SpeciesReference
stoichiometry: 2.0
species: 177422

177422
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Iodine_I2

237247
type: SpeciesReference
stoichiometry: 1.0
species: 161709

237208
type: SpeciesReference
stoichiometry: 2.0
species: 175722

237272
type: SpeciesReference
stoichiometry: 1.0
species: 187032

187032
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Thyroxine_C15H11I4NO4

237297
type: SpeciesReference
stoichiometry: 2.0
species: 177047

237285
type: SpeciesReference
stoichiometry: 1.0
species: 187247

187247
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Triiodothyronine_C15H12I3NO4

237260
type: SpeciesReference
stoichiometry: 1.0
species: 177422

169357
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 1_C45H65N2O52S5

952399
type: Reaction
is: ENSMUSG00000033059.6
is: ENSMUSG00000032648.7
is: ENSMUSG00000021069.7
reactant: 256092
notes: R_GLPASE2 subsystem: Starch and Sucrose Metabolism R_GLPASE2 equation: [c] : glygn3 + (7) h2o --> Tyr-ggn + (7) glc-D R_GLPASE1 subsystem: Starch and Sucrose Metabolism R_GLPASE1 equation: [c] : glygn2 + (3) pi --> dxtrn + (3) g1p
product: 256152
reactant: 256128
reactant: 256116
is: http://identifiers.org/ec-code/2.4.1.1
product: 256164
reactant: 256104
reversible: false
fast: false
product: 256176
product: 256140

256092
type: SpeciesReference
stoichiometry: 1.0
species: 174853

256152
type: SpeciesReference
stoichiometry: 1.0
species: 171860

171860
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: phosphorylase-limit dextrin (glycogenin-1,6{4[1,4-Glc], 4[1,4-Glc]})_C48H81O41X

256128
type: SpeciesReference
stoichiometry: 7.0
species: 175614

256116
type: SpeciesReference
stoichiometry: 3.0
species: 183652

256164
type: SpeciesReference
stoichiometry: 7.0
species: 174274

256104
type: SpeciesReference
stoichiometry: 1.0
species: 174877

174877
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: glycogen, structure 3 (glycogenin-7[1,4-Glc])_C42H71O36X

256176
type: SpeciesReference
stoichiometry: 1.0
species: 164342

164342
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Tyr-194 of apo-glycogenin protein (primer for glycogen synthesis)_XOH

256140
type: SpeciesReference
stoichiometry: 3.0
species: 173377

175288
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GT1b (homo sapiens)_C77H127N5O46FULLRCO

946398
type: Reaction
reactant: 199414
is: ENSMUSG00000022450.4
is: ENSMUSG00000025968.7
is: ENSMUSG00000025534.8
is: http://identifiers.org/ec-code/1.6.99.3
is: ENSMUSG00000022354.3
is: ENSMUSG00000030869.4
is: ENSMUSG00000037916.6
is: ENSMUSG00000022820.2
is: ENSMUSG00000024099.7
reactant: 199426
is: ENSMUSG00000036199.7
is: ENSMUSG00000027673.4
product: 199474
is: ENSMUSG00000024038.8
is: ENSMUSG00000021764.5
reactant: 199438
is: ENSMUSG00000068487.4
is: ENSMUSG00000021606.4
is: ENSMUSG00000000399.6
fast: false
reversible: false
is: ENSMUSG00000030647.7
is: ENSMUSG00000037152.5
is: ENSMUSG00000005510.2
is: ENSMUSG00000026032.7
is: ENSMUSG00000028648.6
is: ENSMUSG00000002416.5
is: ENSMUSG00000025204.3
is: ENSMUSG00000002379.5
product: 199462
is: ENSMUSG00000026895.6
is: ENSMUSG00000071014.3
is: ENSMUSG00000014294.2
is: ENSMUSG00000059734.5
is: ENSMUSG00000016427.6
is: ENSMUSG00000026260.5
is: ENSMUSG00000020022.8
is: ENSMUSG00000013593.5
notes: R_NADH2_DASH_u10m subsystem: Oxidative Phosphorylation R_NADH2_DASH_u10m equation: (5) h[m] + nadh[m] + q10[m] --> (4) h[c] + nad[m] + q10h2[m]
is: ENSMUSG00000041881.4
is: ENSMUSG00000033938.4
is: ENSMUSG00000040048.7
is: ENSMUSG00000039530.8
is: ENSMUSG00000029632.4
name: NADH dehydrogenase, mitochondrial
product: 199450

199414
type: SpeciesReference
stoichiometry: 1.0
species: 184879

184879
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Ubiquinone-10_C59H90O4

199426
type: SpeciesReference
stoichiometry: 5.0
species: 175770

199474
type: SpeciesReference
stoichiometry: 4.0
species: 175722

199438
type: SpeciesReference
stoichiometry: 1.0
species: 181522

199462
type: SpeciesReference
stoichiometry: 1.0
species: 181461

199450
type: SpeciesReference
stoichiometry: 1.0
species: 184903

184903
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Ubiquinol-10_C59H92O4

945258
type: Reaction
reversible: false
product: 190083
reactant: 190059
reactant: 190047
product: 190107
is: http://identifiers.org/ec-code/3.1.3.7
fast: false
product: 190095
is: ENSMUSG00000026617.7
notes: R_BPNT2 subsystem: Nucleotides R_BPNT2 equation: [c] : h2o + paps --> aps + pi R_BPNT subsystem: Nucleotides R_BPNT equation: [c] : h2o + pap --> amp + pi
reactant: 190071

190083
type: SpeciesReference
stoichiometry: 2.0
species: 183652

190059
type: SpeciesReference
stoichiometry: 1.0
species: 183131

183131
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3'-Phosphoadenylyl sulfate_C10H11N5O13P2S

190047
type: SpeciesReference
stoichiometry: 1.0
species: 183107

183107
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Adenosine 3',5'-bisphosphate_C10H11N5O10P2

190107
type: SpeciesReference
stoichiometry: 1.0
species: 166219

190095
type: SpeciesReference
stoichiometry: 1.0
species: 166507

166507
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Adenosine 5'-phosphosulfate_C10H12N5O10PS

190071
type: SpeciesReference
stoichiometry: 2.0
species: 175614

948298
type: Reaction
is: ENSMUSG00000054008.6
reactant: 216472
product: 216508
is: ENSMUSG00000039308.3
reactant: 216448
reactant: 216460
fast: false
product: 216484
is: ENSMUSG00000027977.6
product: 216496
is: ENSMUSG00000027971.5
reversible: false
product: 216520
name: GlcNAc N-deacetylase / N-sulfotransferase
notes: R_GLCNACDASg subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACDASg equation: [g] : (4) h2o + hs_pre9 + (4) paps --> (4) ac + (4) h + hs_pre10 + (4) pap

216472
type: SpeciesReference
stoichiometry: 4.0
species: 183143

183143
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: _3'-Phosphoadenylyl sulfate_C10H11N5O13P2S

216508
type: SpeciesReference
stoichiometry: 4.0
species: 183120

183120
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Adenosine 3',5'-bisphosphate_C10H11N5O10P2

216448
type: SpeciesReference
stoichiometry: 1.0
species: 176938

176938
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: heparan sulfate, precursor 9_C87H129N5O69X

216460
type: SpeciesReference
stoichiometry: 4.0
species: 175638

216484
type: SpeciesReference
stoichiometry: 4.0
species: 164462

164462
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Acetate_C2H3O2

216496
type: SpeciesReference
stoichiometry: 4.0
species: 175746

216520
type: SpeciesReference
stoichiometry: 1.0
species: 176770

184423
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Prostaglandin D2_C20H31O5

955199
type: Reaction
reactant: 283199
notes: R_BDG2HCGHD subsystem: Stilbene, coumarine and lignin biosynthesis R_BDG2HCGHD equation: [c] : bdg2hc + h2o --> 2coum + glc-D + h
product: 283211
is: http://identifiers.org/ec-code/3.2.1.21
fast: false
reactant: 283187
product: 283223
name: beta-D-Glucosyl-2-coumarinate glucohydrolase
is: ENSMUSG00000067313.4
product: 283235
reversible: false

283199
type: SpeciesReference
stoichiometry: 1.0
species: 167025

167025
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: cis-beta-D-Glucosyl-2-hydroxycinnamate_C15H18O8

283211
type: SpeciesReference
stoichiometry: 1.0
species: 161294

161294
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: cis-2-Hydroxy cinnamate_C9H7O3

283187
type: SpeciesReference
stoichiometry: 1.0
species: 175614

283223
type: SpeciesReference
stoichiometry: 1.0
species: 174274

283235
type: SpeciesReference
stoichiometry: 1.0
species: 175722

952159
type: Reaction
notes: R_DCK1n subsystem: Nucleotides R_DCK1n equation: [n] : atp + dcyt <==> adp + dcmp + h R_DCK2n subsystem: Nucleotides R_DCK2n equation: [n] : dcyt + utp <==> dcmp + h + udp
product: 253098
reactant: 253049
product: 253122
product: 253086
reactant: 253074
product: 253110
is: http://identifiers.org/ec-code/2.7.1.74
fast: false
reversible: true
reactant: 253062
is: ENSMUSG00000029366.8

253098
type: SpeciesReference
stoichiometry: 1.0
species: 187645

187645
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: UDP_C9H11N2O12P2

253049
type: SpeciesReference
stoichiometry: 2.0
species: 170242

170242
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Deoxycytidine_C9H13N3O4

253122
type: SpeciesReference
stoichiometry: 2.0
species: 170097

170097
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: dCMP_C9H12N3O7P

253086
type: SpeciesReference
stoichiometry: 2.0
species: 175782

175782
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: H+_H

253074
type: SpeciesReference
stoichiometry: 1.0
species: 166940

166940
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: ATP_C10H12N5O13P3

253110
type: SpeciesReference
stoichiometry: 1.0
species: 165423

165423
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: ADP_C10H12N5O10P2

253062
type: SpeciesReference
stoichiometry: 1.0
species: 188128

188128
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: UTP_C9H11N2O15P3

947757
type: Reaction
notes: R_CITt4_2 subsystem: Transport, Extracellular R_CITt4_2 equation: cit[e] + (2) na1[e] <==> cit[c] + (2) na1[c] R_SUCCt4_2 subsystem: Transport, Extracellular R_SUCCt4_2 equation: (2) na1[e] + succ[e] <==> (2) na1[c] + succ[c]
reversible: true
fast: false
product: 212258
reactant: 212234
reactant: 212222
product: 212283
product: 212271
reactant: 212246
is: ENSMUSG00000001095.4

212258
type: SpeciesReference
stoichiometry: 1.0
species: 186077

186077
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Succinate_C4H4O4

212234
type: SpeciesReference
stoichiometry: 1.0
species: 186089

186089
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Succinate_C4H4O4

212222
type: SpeciesReference
stoichiometry: 4.0
species: 181389

212283
type: SpeciesReference
stoichiometry: 1.0
species: 168136

168136
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Citrate_C6H5O7

212271
type: SpeciesReference
stoichiometry: 4.0
species: 181377

212246
type: SpeciesReference
stoichiometry: 1.0
species: 168148

168148
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Citrate_C6H5O7

182491
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: octanoate (n-C8:0)_C8H15O2

162701
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4 hydroxy tolbutamide_C12H18N2O4S

945209
type: Reaction
notes: R_TRDRm subsystem: Nucleotides R_TRDRm equation: [m] : h + nadph + trdox --> nadp + trdrd
product: 189795
reactant: 189759
is: ENSMUSG00000000811.5
reversible: false
reactant: 189747
product: 189783
is: ENSMUSG00000075704.6
reactant: 189771
name: thioredoxin reductase (NADPH)
fast: false
is: http://identifiers.org/ec-code/1.8.1.9

189795
type: SpeciesReference
stoichiometry: 1.0
species: 181583

189759
type: SpeciesReference
stoichiometry: 1.0
species: 175770

189747
type: SpeciesReference
stoichiometry: 1.0
species: 181643

189783
type: SpeciesReference
stoichiometry: 1.0
species: 187211

187211
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Reduced thioredoxin_XH2

189771
type: SpeciesReference
stoichiometry: 1.0
species: 187185

187185
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Oxidized thioredoxin_X

948058
type: Reaction
product: 214163
reactant: 214127
product: 214151
notes: R_CHOLt4 subsystem: Transport, Extracellular R_CHOLt4 equation: chol[e] + na1[e] <==> chol[c] + na1[c]
is: ENSMUSG00000023945.5
reactant: 214139
fast: false
reversible: true
name: choline, sodium cotransport

214163
type: SpeciesReference
stoichiometry: 1.0
species: 181377

214127
type: SpeciesReference
stoichiometry: 1.0
species: 181389

214151
type: SpeciesReference
stoichiometry: 1.0
species: 167796

167796
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Choline_C5H14NO

214139
type: SpeciesReference
stoichiometry: 1.0
species: 167808

167808
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Choline_C5H14NO

166399
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: P1,P4-Bis(5'-adenosyl) tetraphosphate_C20H24N10O19P4

953517
type: Reaction
product: 267616
product: 267580
reactant: 267556
product: 267604
reactant: 267568
fast: false
reactant: 267531
product: 267628
reactant: 267543
reactant: 267519
is: http://identifiers.org/ec-code/1.15.1.1
reactant: 267507
reversible: false
is: ENSMUSG00000022982.8
product: 267640
notes: R_SPODMn subsystem: ROS Detoxification R_SPODMn equation: [n] : (2) h + (2) o2s --> h2o2 + o2 R_SPODMx subsystem: ROS Detoxification R_SPODMx equation: [x] : (2) h + (2) o2s --> h2o2 + o2 R_SPODM subsystem: ROS Detoxification R_SPODM equation: [c] : (2) h + (2) o2s --> h2o2 + o2
product: 267592

267616
type: SpeciesReference
stoichiometry: 1.0
species: 175602

267580
type: SpeciesReference
stoichiometry: 1.0
species: 182214

267556
type: SpeciesReference
stoichiometry: 2.0
species: 175806

267604
type: SpeciesReference
stoichiometry: 1.0
species: 182190

182190
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: O2_O2

267568
type: SpeciesReference
stoichiometry: 2.0
species: 175722

267531
type: SpeciesReference
stoichiometry: 2.0
species: 175782

267628
type: SpeciesReference
stoichiometry: 1.0
species: 175542

267543
type: SpeciesReference
stoichiometry: 2.0
species: 182226

182226
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Superoxide anion_O2

267519
type: SpeciesReference
stoichiometry: 2.0
species: 182274

182274
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Superoxide anion_O2

267507
type: SpeciesReference
stoichiometry: 2.0
species: 182262

182262
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Superoxide anion_O2

267640
type: SpeciesReference
stoichiometry: 1.0
species: 182154

267592
type: SpeciesReference
stoichiometry: 1.0
species: 175590

175590
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Hydrogen peroxide_H2O2

169719
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Cysteamine_C2H8NS

955825
type: Reaction
reversible: false
product: 291229
product: 291241
reactant: 291181
reactant: 291169
reactant: 291145
product: 291265
is: ENSMUSG00000040820.7
is: http://identifiers.org/ec-code/6.3.4.15
reactant: 291133
product: 291277
product: 291301
product: 291289
reactant: 291109
fast: false
product: 291313
reactant: 291193
reactant: 291157
reactant: 291205
product: 291325
reactant: 291217
product: 291337
reactant: 291121
notes: R_BACCL subsystem: Biotin Metabolism R_BACCL equation: [c] : atp + btn + h --> btamp + ppi R_BTNPLm subsystem: Biotin Metabolism R_BTNPLm equation: [m] : apoC-Lys + btamp --> amp + apoC-Lys_btn + h R_BTNPL subsystem: Biotin Metabolism R_BTNPL equation: [c] : apoC-Lys + btamp --> amp + apoC-Lys_btn + h R_BACCLm subsystem: Biotin Metabolism R_BACCLm equation: [m] : atp + btn + h --> btamp + ppi
product: 291253

291229
type: SpeciesReference
stoichiometry: 1.0
species: 166267

166267
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: AMP_C10H12N5O7P

291241
type: SpeciesReference
stoichiometry: 1.0
species: 166423

166423
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Holocarboxylase (biotin covalent bound to Lys residue of apoC)_C16H27N4O3SX

291181
type: SpeciesReference
stoichiometry: 1.0
species: 167242

167242
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Biotinyl-5'-AMP_C20H27N7O9PS

291169
type: SpeciesReference
stoichiometry: 1.0
species: 166928

291145
type: SpeciesReference
stoichiometry: 1.0
species: 167254

167254
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Biotinyl-5'-AMP_C20H27N7O9PS

291265
type: SpeciesReference
stoichiometry: 1.0
species: 166435

166435
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Holocarboxylase (biotin covalent bound to Lys residue of apoC)_C16H27N4O3SX

291133
type: SpeciesReference
stoichiometry: 1.0
species: 167303

167303
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Biotin_C10H15N2O3S

291277
type: SpeciesReference
stoichiometry: 1.0
species: 183929

183929
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Diphosphate_HO7P2

291301
type: SpeciesReference
stoichiometry: 1.0
species: 167242

291289
type: SpeciesReference
stoichiometry: 1.0
species: 166219

291109
type: SpeciesReference
stoichiometry: 1.0
species: 166447

166447
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Apocarboxylase (Lys residue)_C6H13N2OX

291313
type: SpeciesReference
stoichiometry: 1.0
species: 175722

291193
type: SpeciesReference
stoichiometry: 1.0
species: 175770

291157
type: SpeciesReference
stoichiometry: 1.0
species: 167278

167278
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Biotin_C10H15N2O3S

291205
type: SpeciesReference
stoichiometry: 1.0
species: 175722

291325
type: SpeciesReference
stoichiometry: 1.0
species: 175770

291217
type: SpeciesReference
stoichiometry: 1.0
species: 166459

166459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Apocarboxylase (Lys residue)_C6H13N2OX

291337
type: SpeciesReference
stoichiometry: 1.0
species: 183917

291121
type: SpeciesReference
stoichiometry: 1.0
species: 166904

291253
type: SpeciesReference
stoichiometry: 1.0
species: 167254

179218
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Lactose_C12H22O11

949596
type: Reaction
product: 228264
reactant: 228191
reactant: 228228
product: 228276
is: http://identifiers.org/ec-code/3.2.1.113
reactant: 228179
reactant: 228119
reactant: 228143
fast: false
reactant: 228131
reactant: 228204
reactant: 228216
product: 228300
product: 228337
product: 228312
reactant: 228167
reactant: 228155
reactant: 228107
product: 228252
notes: R_MM5bg subsystem: N-Glycan Biosynthesis R_MM5bg equation: [g] : h2o + m5masnB1 --> m4masn + man R_MM7Cbg subsystem: N-Glycan Biosynthesis R_MM7Cbg equation: [g] : h2o + m7masnC --> m6masnC + man R_MM6B2g subsystem: N-Glycan Biosynthesis R_MM6B2g equation: [g] : h2o + m6masnB2 --> m5masnB2 + man R_MM6bg subsystem: N-Glycan Biosynthesis R_MM6bg equation: [g] : h2o + m6masnC --> m5masnC + man R_MM8Ag subsystem: N-Glycan Biosynthesis R_MM8Ag equation: [g] : h2o + m8masn --> m7masnA + man R_MM6ag subsystem: N-Glycan Biosynthesis R_MM6ag equation: [g] : h2o + m6masnA --> m5masnC + man R_MM8Cg subsystem: N-Glycan Biosynthesis R_MM8Cg equation: [g] : h2o + m8masn --> m7masnC + man R_MM7Cag subsystem: N-Glycan Biosynthesis R_MM7Cag equation: [g] : h2o + m7masnA --> m6masnC + man R_MM6B1ag subsystem: N-Glycan Biosynthesis R_MM6B1ag equation: [g] : h2o + m6masnB1 --> m5masnB1 + man R_MM7Ag subsystem: N-Glycan Biosynthesis R_MM7Ag equation: [g] : h2o + m7masnA --> m6masnA + man R_MM7B2g subsystem: N-Glycan Biosynthesis R_MM7B2g equation: [g] : h2o + m7masnB --> m6masnB2 + man R_MM6B1bg subsystem: N-Glycan Biosynthesis R_MM6B1bg equation: [g] : h2o + m6masnB2 --> m5masnB1 + man R_MM5ag subsystem: N-Glycan Biosynthesis R_MM5ag equation: [g] : h2o + m5masnC --> m4masn + man R_MM5cg subsystem: N-Glycan Biosynthesis R_MM5cg equation: [g] : h2o + m5masnB2 --> m4masn + man R_MM7B1g subsystem: N-Glycan Biosynthesis R_MM7B1g equation: [g] : h2o + m7masnB --> m6masnB1 + man
is: ENSMUSG00000037306.4
product: 228361
product: 228240
product: 228324
reversible: false
product: 228349
reactant: 228095
product: 228288

228264
type: SpeciesReference
stoichiometry: 2.0
species: 180052

180052
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (alpha-D-mannosyl)5-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C52H87N2O40X

228191
type: SpeciesReference
stoichiometry: 2.0
species: 180113

180113
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X

228228
type: SpeciesReference
stoichiometry: 1.0
species: 180089

180089
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X

228276
type: SpeciesReference
stoichiometry: 1.0
species: 180198

180198
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform C (protein)_C64H107N2O50X

228179
type: SpeciesReference
stoichiometry: 2.0
species: 180161

180161
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform A (protein)_C64H107N2O50X

228119
type: SpeciesReference
stoichiometry: 1.0
species: 180052

228143
type: SpeciesReference
stoichiometry: 15.0
species: 175638

228131
type: SpeciesReference
stoichiometry: 1.0
species: 180198

228204
type: SpeciesReference
stoichiometry: 2.0
species: 180234

180234
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C70H117N2O55X

228216
type: SpeciesReference
stoichiometry: 1.0
species: 180028

180028
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (alpha-D-mannosyl)5-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C52H87N2O40X

228300
type: SpeciesReference
stoichiometry: 2.0
species: 180125

180125
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X

228337
type: SpeciesReference
stoichiometry: 15.0
species: 180536

228312
type: SpeciesReference
stoichiometry: 1.0
species: 180161

228167
type: SpeciesReference
stoichiometry: 1.0
species: 180125

228155
type: SpeciesReference
stoichiometry: 1.0
species: 180101

180101
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X

228107
type: SpeciesReference
stoichiometry: 1.0
species: 180040

180040
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (alpha-D-mannosyl)5-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C52H87N2O40X

228252
type: SpeciesReference
stoichiometry: 1.0
species: 180040

228361
type: SpeciesReference
stoichiometry: 1.0
species: 180089

228240
type: SpeciesReference
stoichiometry: 3.0
species: 179992

179992
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C46H77N2O35X

228324
type: SpeciesReference
stoichiometry: 1.0
species: 180113

228349
type: SpeciesReference
stoichiometry: 2.0
species: 180028

228095
type: SpeciesReference
stoichiometry: 2.0
species: 180173

180173
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein)_C64H107N2O50X

228288
type: SpeciesReference
stoichiometry: 1.0
species: 180101

954009
type: Reaction
modifier: 272452
modifier: 272440
is: http://identifiers.org/ec-code/1.1.1.2
product: 272367
product: 272404
product: 272330
reactant: 272183
reactant: 272245
is: ENSMUSG00000060938.6
fast: false
product: 272306
reactant: 272270
product: 272355
is: ENSMUSG00000063754.4
product: 272294
reactant: 272208
reactant: 272195
reversible: false
product: 272392
product: 272342
reactant: 272257
is: http://identifiers.org/ec-code/1.1.1.21
reactant: 272221
reactant: 272282
is: ENSMUSG00000066489.1
modifier: 272428
modifier: 272464
product: 272380
is: ENSMUSG00000059150.2
reactant: 272233
notes: R_ARABR subsystem: Pentose and Glucuronate Interconversions R_ARABR equation: [c] : arab-L + h + nadph --> abt + nadp R_LALDO2 subsystem: Pyruvate Metabolism R_LALDO2 equation: [c] : h + mthgxl + nadph --> lald-D + nadp R_ALCD2yf subsystem: Glycolysis/Gluconeogenesis R_ALCD2yf equation: [c] : etoh + nadp --> acald + h + nadph R_ALR3 subsystem: Pyruvate Metabolism R_ALR3 equation: [c] : acetol + h + nadph --> 12ppd-S + nadp R_SBTR subsystem: Fructose and Mannose Metabolism R_SBTR equation: [c] : glc-D + h + nadph --> nadp + sbt-D R_GALOR subsystem: Galactose metabolism R_GALOR equation: [c] : gal + h + nadph <==> galt + nadp R_ALR2 subsystem: Pyruvate Metabolism R_ALR2 equation: [c] : h + mthgxl + nadph --> acetol + nadp R_PPDOy subsystem: Pyruvate Metabolism R_PPDOy equation: [c] : h + lald-D + nadph --> 12ppd-R + nadp
modifier: 272416
product: 272318

173850
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Galactitol_C6H14O6

272367
type: SpeciesReference
stoichiometry: 1.0
species: 185349

185349
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Sorbitol_C6H14O6

272404
type: SpeciesReference
stoichiometry: 1.0
species: 181631

272330
type: SpeciesReference
stoichiometry: 1.0
species: 164534

272183
type: SpeciesReference
stoichiometry: 2.0
species: 181198

181198
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Methylglyoxal_C3H4O2

272245
type: SpeciesReference
stoichiometry: 1.0
species: 179122

272306
type: SpeciesReference
stoichiometry: 1.0
species: 164414

164414
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Arabinitol_C5H12O5

272270
type: SpeciesReference
stoichiometry: 6.0
species: 175722

272355
type: SpeciesReference
stoichiometry: 1.0
species: 179122

272294
type: SpeciesReference
stoichiometry: 1.0
species: 160907

160907
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: (S)-Propane-1,2-diol_C3H8O2

272208
type: SpeciesReference
stoichiometry: 1.0
species: 166519

166519
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Arabinose_C5H10O5

272195
type: SpeciesReference
stoichiometry: 1.0
species: 181558

272392
type: SpeciesReference
stoichiometry: 1.0
species: 175722

272342
type: SpeciesReference
stoichiometry: 6.0
species: 181558

272257
type: SpeciesReference
stoichiometry: 1.0
species: 164655

164655
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Acetol_C3H6O2

272221
type: SpeciesReference
stoichiometry: 1.0
species: 172403

172403
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Ethanol_C2H6O

272282
type: SpeciesReference
stoichiometry: 6.0
species: 181631

272380
type: SpeciesReference
stoichiometry: 1.0
species: 164655

272233
type: SpeciesReference
stoichiometry: 1.0
species: 174274

173583
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Galactose_C6H12O6

272318
type: SpeciesReference
stoichiometry: 1.0
species: 160895

160895
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: (R)-Propane-1,2-diol_C3H8O2

946868
type: Reaction
product: 204239
product: 204227
is: ENSMUSG00000020229.4
product: 204215
reactant: 204191
is: ENSMUSG00000020226.7
reactant: 204179
product: 204263
is: ENSMUSG00000033255.5
reversible: true
notes: R_GLCt4 subsystem: Transport, Extracellular R_GLCt4 equation: glc-D[e] + na1[e] <==> glc-D[c] + na1[c] R_FRUt4 subsystem: Transport, Extracellular R_FRUt4 equation: fru[e] + na1[e] <==> fru[c] + na1[c] R_MANt4 subsystem: Transport, Extracellular R_MANt4 equation: man[e] + na1[e] <==> man[c] + na1[c] R_GALt4 subsystem: Transport, Extracellular R_GALt4 equation: gal[e] + na1[e] <==> gal[c] + na1[c]
product: 204251
reactant: 204203
is: ENSMUSG00000028544.6
fast: false
reactant: 204167
reactant: 204155

204239
type: SpeciesReference
stoichiometry: 4.0
species: 181377

204227
type: SpeciesReference
stoichiometry: 1.0
species: 173583

204215
type: SpeciesReference
stoichiometry: 1.0
species: 180512

204191
type: SpeciesReference
stoichiometry: 1.0
species: 174286

204179
type: SpeciesReference
stoichiometry: 4.0
species: 181389

204263
type: SpeciesReference
stoichiometry: 1.0
species: 174274

204251
type: SpeciesReference
stoichiometry: 1.0
species: 172932

204203
type: SpeciesReference
stoichiometry: 1.0
species: 172944

204167
type: SpeciesReference
stoichiometry: 1.0
species: 173595

173595
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: D-Galactose_C6H12O6

204155
type: SpeciesReference
stoichiometry: 1.0
species: 180524

180524
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: D-Mannose_C6H12O6

185777
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: Sphingosine_C18H38NO2

174418
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Glutamate 5-phosphate_C5H8NO7P

187044
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Thyroxine_C15H11I4NO4

955993
type: Reaction
reversible: false
is: http://identifiers.org/ec-code/4.1.1.22
reactant: 292327
fast: false
name: histidine decarboxylase
product: 292339
reactant: 292315
product: 292351
notes: R_HISDC subsystem: Histidine Metabolism R_HISDC equation: [c] : h + his-L --> co2 + hista
is: ENSMUSG00000027360.4

292327
type: SpeciesReference
stoichiometry: 1.0
species: 175722

292339
type: SpeciesReference
stoichiometry: 1.0
species: 176241

292315
type: SpeciesReference
stoichiometry: 1.0
species: 176216

176216
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Histidine_C6H9N3O2

292351
type: SpeciesReference
stoichiometry: 1.0
species: 168436

948815
type: Reaction
notes: R_SAMHISTA subsystem: Histidine Metabolism R_SAMHISTA equation: [c] : amet + hista --> ahcys + h + mhista
reactant: 220511
product: 220548
name: S-Adenosyl-L-methionine:histamine N-tele-methyltransferase
product: 220536
reversible: false
reactant: 220499
is: http://identifiers.org/ec-code/2.1.1.8
product: 220524
fast: false
is: ENSMUSG00000026986.7

220511
type: SpeciesReference
stoichiometry: 1.0
species: 176241

220548
type: SpeciesReference
stoichiometry: 1.0
species: 175722

220536
type: SpeciesReference
stoichiometry: 1.0
species: 180824

220499
type: SpeciesReference
stoichiometry: 1.0
species: 166159

220524
type: SpeciesReference
stoichiometry: 1.0
species: 165737

165737
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

947684
type: Reaction
reactant: 211572
fast: false
product: 211584
reactant: 211548
reactant: 211560
is: ENSMUSG00000025161.8
notes: R_D_DASH_LACt2 subsystem: Transport, Extracellular R_D_DASH_LACt2 equation: h[e] + lac-D[e] <==> h[c] + lac-D[c] R_L_DASH_LACt2r subsystem: Transport, Extracellular R_L_DASH_LACt2r equation: h[e] + lac-L[e] <==> h[c] + lac-L[c] R_PYRt2r subsystem: Transport, Extracellular R_PYRt2r equation: h[e] + pyr[e] <==> h[c] + pyr[c] R_ACETONEt2 subsystem: Transport, Extracellular R_ACETONEt2 equation: acetone[e] + h[e] <==> acetone[c] + h[c] R_2HBt2 subsystem: Transport, Extracellular R_2HBt2 equation: _2hb[e] + h[e] <==> 2hb[c] + h[c]
reactant: 211536
product: 211632
reversible: true
product: 211608
product: 211596
reactant: 211524
product: 211620
reactant: 211512
product: 211644

211572
type: SpeciesReference
stoichiometry: 1.0
species: 184831

184831
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Pyruvate_C3H3O3

211584
type: SpeciesReference
stoichiometry: 1.0
species: 161381

161381
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _2-Hydroxybutyrate_C4H7O3

211548
type: SpeciesReference
stoichiometry: 1.0
species: 179062

211560
type: SpeciesReference
stoichiometry: 1.0
species: 161393

161393
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: _2-Hydroxybutyrate_C4H7O3

211536
type: SpeciesReference
stoichiometry: 1.0
species: 179098

211632
type: SpeciesReference
stoichiometry: 1.0
species: 179050

211608
type: SpeciesReference
stoichiometry: 1.0
species: 184819

211596
type: SpeciesReference
stoichiometry: 1.0
species: 164667

164667
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Acetone_C3H6O

211524
type: SpeciesReference
stoichiometry: 5.0
species: 175734

211620
type: SpeciesReference
stoichiometry: 1.0
species: 179086

211512
type: SpeciesReference
stoichiometry: 1.0
species: 164679

164679
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Acetone_C3H6O

211644
type: SpeciesReference
stoichiometry: 5.0
species: 175722

164198
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: R total Coenzyme A_CO2FULLRC21H31N7O15P3S

180186
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein)_C64H107N2O50X

162689
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _4-Methylpentanal_C6H12O

173631
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (Gal)4 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)1 (Cer)1_C78H135N4O46FULLRCO

180982
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: _1D-myo-Inositol 1-phosphate_C6H11O9P

949801
type: Reaction
reversible: false
product: 229920
is: http://identifiers.org/ec-code/1.13.11.27
fast: false
reactant: 229859
notes: R_34HPPOR subsystem: Tyrosine metabolism R_34HPPOR equation: [c] : 34hpp + o2 --> co2 + hgentis R_PPOR subsystem: Phenylalanine metabolism R_PPOR equation: [c] : o2 + phpyr --> 2hyoxplac + co2
product: 229908
product: 229896
is: ENSMUSG00000029445.6
reactant: 229884
reactant: 229871

229920
type: SpeciesReference
stoichiometry: 2.0
species: 168436

229859
type: SpeciesReference
stoichiometry: 1.0
species: 183568

183568
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Phenylpyruvate_C9H7O3

229908
type: SpeciesReference
stoichiometry: 1.0
species: 161405

229896
type: SpeciesReference
stoichiometry: 1.0
species: 176204

176204
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Homogentisate_C8H7O4

229884
type: SpeciesReference
stoichiometry: 2.0
species: 182154

229871
type: SpeciesReference
stoichiometry: 1.0
species: 161636

161636
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-(4-Hydroxyphenyl)pyruvate_C9H7O4

174685
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Glyceraldehyde_C3H6O3

179364
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Leukotriene D4_C25H39N2O6S

187368
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: testosterone glucuronide_C25H36O8

946566
type: Reaction
product: 201420
reversible: true
product: 201407
name: (R)-3-Hydroxybutanoate:NAD+ oxidoreductase
notes: R_BDHm subsystem: Butanoate Metabolism R_BDHm equation: [m] : bhb + nad <==> acac + h + nadh
product: 201432
is: http://identifiers.org/ec-code/1.1.1.30
fast: false
reactant: 201395
reactant: 201383
is: ENSMUSG00000046598.7

201420
type: SpeciesReference
stoichiometry: 1.0
species: 175770

201407
type: SpeciesReference
stoichiometry: 1.0
species: 164510

201432
type: SpeciesReference
stoichiometry: 1.0
species: 181522

201395
type: SpeciesReference
stoichiometry: 1.0
species: 181461

201383
type: SpeciesReference
stoichiometry: 1.0
species: 167061

167061
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: (R)-3-Hydroxybutanoate_C4H7O3

165221
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: O-Acetylcarnitine_C9H17NO4

185048
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: cis-13-retinol_C20H30O

162314
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Sulfopyruvate_C3H2O6S

169939
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: dAMP_C10H12N5O6P

951919
type: Reaction
product: 250136
product: 250160
is: http://identifiers.org/ec-code/6.3.2.6
product: 250148
reactant: 250088
is: http://identifiers.org/ec-code/4.1.1.21
product: 250124
reactant: 250064
reversible: true
is: ENSMUSG00000029247.8
reactant: 250100
notes: R_AIRCr subsystem: IMP Biosynthesis R_AIRCr equation: [c] : air + co2 <==> 5aizc + h R_PRASCS subsystem: IMP Biosynthesis R_PRASCS equation: [c] : 5aizc + asp-L + atp <==> 25aics + adp + h + pi
fast: false
product: 250172
reactant: 250076
reactant: 250112

250136
type: SpeciesReference
stoichiometry: 1.0
species: 183652

250160
type: SpeciesReference
stoichiometry: 1.0
species: 162979

162979
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate_C9H11N3O9P

250148
type: SpeciesReference
stoichiometry: 1.0
species: 165387

250088
type: SpeciesReference
stoichiometry: 1.0
species: 165822

165822
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-amino-1-(5-phospho-D-ribosyl)imidazole_C8H12N3O7P

250124
type: SpeciesReference
stoichiometry: 1.0
species: 161209

161209
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate_C13H15N4O12P

250064
type: SpeciesReference
stoichiometry: 1.0
species: 166904

250100
type: SpeciesReference
stoichiometry: 1.0
species: 166868

166868
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Aspartate_C4H6NO4

250172
type: SpeciesReference
stoichiometry: 2.0
species: 175722

250076
type: SpeciesReference
stoichiometry: 1.0
species: 162979

250112
type: SpeciesReference
stoichiometry: 1.0
species: 168436

949055
type: Reaction
is: ENSMUSG00000038633.4
notes: R_DHCRD1 subsystem: Sphingolipid Metabolism R_DHCRD1 equation: [c] : dhcrm_hs + nadp --> crm_hs + h + nadph R_DHCRD2 subsystem: Sphingolipid Metabolism R_DHCRD2 equation: [c] : dhcrm_hs + fad --> crm_hs + fadh2
product: 223317
reversible: false
reactant: 223269
reactant: 223281
reactant: 223293
fast: false
product: 223341
product: 223329
product: 223305
is: ENSMUSG00000038768.6

223317
type: SpeciesReference
stoichiometry: 2.0
species: 168738

223269
type: SpeciesReference
stoichiometry: 1.0
species: 172487

172487
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

223281
type: SpeciesReference
stoichiometry: 2.0
species: 170700

170700
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: dihydroceramide (homo sapiens)_C18H38NO2FULLRCO

223293
type: SpeciesReference
stoichiometry: 1.0
species: 181558

223341
type: SpeciesReference
stoichiometry: 1.0
species: 181631

223329
type: SpeciesReference
stoichiometry: 1.0
species: 175722

223305
type: SpeciesReference
stoichiometry: 1.0
species: 172535

172439
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Fructose 1-phosphate_C6H11O9P

172246
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Estrone_C18H22O2

182142
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-(omega)-Hydroxyarginine_C6H15N4O3

956065
type: Reaction
notes: R_HMGLx subsystem: Cholesterol Metabolism R_HMGLx equation: [x] : hmgcoa --> acac + accoa R_HMGLm subsystem: Cholesterol Metabolism R_HMGLm equation: [m] : hmgcoa --> acac + accoa
is: http://identifiers.org/ec-code/4.1.3.4
product: 293075
is: ENSMUSG00000028672.6
product: 293051
product: 293087
product: 293063
reactant: 293039
fast: false
reactant: 293027
reversible: false

293075
type: SpeciesReference
stoichiometry: 1.0
species: 164522

164522
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Acetoacetate_C4H5O3

293051
type: SpeciesReference
stoichiometry: 1.0
species: 164510

293087
type: SpeciesReference
stoichiometry: 1.0
species: 164643

293063
type: SpeciesReference
stoichiometry: 1.0
species: 164607

293039
type: SpeciesReference
stoichiometry: 1.0
species: 176313

176313
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598

293027
type: SpeciesReference
stoichiometry: 1.0
species: 176289

170724
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Dehydroascorbate_C6H6O6

186332
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Thiocyanate_CNS

183832
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: (R)-Pantothenate_C9H16NO5

951269
type: Reaction
product: 244791
is: ENSMUSG00000020229.4
reversible: true
reactant: 244754
notes: R_GLCt4 subsystem: Transport, Extracellular R_GLCt4 equation: glc-D[e] + na1[e] <==> glc-D[c] + na1[c] R_INSTt4 subsystem: Transport, Extracellular R_INSTt4 equation: inost[e] + na1[e] <==> inost[c] + na1[c] R_NAt subsystem: Transport, Extracellular R_NAt equation: na1[e] <==> na1[c]
product: 244816
is: ENSMUSG00000079514.1
product: 244804
fast: false
is: ENSMUSG00000020226.7
reactant: 244778
reactant: 244766

244791
type: SpeciesReference
stoichiometry: 3.0
species: 181377

244754
type: SpeciesReference
stoichiometry: 3.0
species: 181389

244816
type: SpeciesReference
stoichiometry: 1.0
species: 174274

244804
type: SpeciesReference
stoichiometry: 1.0
species: 177349

177349
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: myo-Inositol_C6H12O6

244778
type: SpeciesReference
stoichiometry: 1.0
species: 177361

177361
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: myo-Inositol_C6H12O6

244766
type: SpeciesReference
stoichiometry: 1.0
species: 174286

948310
type: Reaction
reversible: false
reactant: 216568
is: ENSMUSG00000025137.7
fast: false
product: 216580
reactant: 216544
is: http://identifiers.org/ec-code/2.7.7.14
product: 216592
reactant: 216532
notes: R_PETHCT subsystem: Glycerophospholipid Metabolism R_PETHCT equation: [c] : ctp + ethamp + h --> cdpea + ppi R_EPCTX subsystem: Glycerophospholipid Metabolism R_EPCTX equation: [c] : 2ameph + ctp + h --> cmp2amep + ppi
product: 216605
reactant: 216556

216568
type: SpeciesReference
stoichiometry: 2.0
species: 169615

216580
type: SpeciesReference
stoichiometry: 1.0
species: 167723

216544
type: SpeciesReference
stoichiometry: 1.0
species: 172379

216592
type: SpeciesReference
stoichiometry: 1.0
species: 168304

168304
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514

216532
type: SpeciesReference
stoichiometry: 1.0
species: 161258

216605
type: SpeciesReference
stoichiometry: 2.0
species: 183917

216556
type: SpeciesReference
stoichiometry: 2.0
species: 175722

183496
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Phenylalanine_C9H11NO2

951847
type: Reaction
notes: R_PCLYSOX subsystem: Lysine Metabolism R_PCLYSOX equation: [c] : akg + o2 + pcollglys --> co2 + pcollg5hlys + succ
fast: false
reactant: 249449
is: ENSMUSG00000004846.3
product: 249510
product: 249498
is: ENSMUSG00000032374.7
product: 249485
reactant: 249473
is: ENSMUSG00000019055.6
is: http://identifiers.org/ec-code/1.14.11.4
name: Procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase
reversible: false
reactant: 249461

249449
type: SpeciesReference
stoichiometry: 1.0
species: 183228

183228
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Procollagen L-lysine_C7H14N3O2R2

249510
type: SpeciesReference
stoichiometry: 1.0
species: 168436

249498
type: SpeciesReference
stoichiometry: 1.0
species: 186077

249485
type: SpeciesReference
stoichiometry: 1.0
species: 183216

249473
type: SpeciesReference
stoichiometry: 1.0
species: 182154

249461
type: SpeciesReference
stoichiometry: 1.0
species: 165871

945185
type: Reaction
is: ENSMUSG00000029836.8
product: 189649
is: ENSMUSG00000040660.5
reactant: 189613
reactant: 189601
is: ENSMUSG00000074843.1
is: ENSMUSG00000003053.7
is: ENSMUSG00000025479.6
is: ENSMUSG00000042248.2
is: ENSMUSG00000025197.7
product: 189661
notes: R_P4502A6 subsystem: CYP Metabolism R_P4502A6 equation: [c] : coumarin + h + nadph + o2 --> h2o + hcoumarin + nadp
fast: false
reversible: false
is: ENSMUSG00000062624.4
is: ENSMUSG00000025003.3
product: 189637
reactant: 189589
is: ENSMUSG00000067225.1
is: ENSMUSG00000059647.3
is: ENSMUSG00000074882.2
name: cytochrome P450 2A6
is: ENSMUSG00000032808.2
is: ENSMUSG00000054827.5
is: ENSMUSG00000078787.1
is: ENSMUSG00000074254.2
is: ENSMUSG00000067229.2
is: ENSMUSG00000067231.3
is: ENSMUSG00000030483.7
reactant: 189625
is: ENSMUSG00000040583.6
is: ENSMUSG00000025004.5

189649
type: SpeciesReference
stoichiometry: 1.0
species: 175914

175914
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: hydroxy coumarin_C9H6O3

189613
type: SpeciesReference
stoichiometry: 1.0
species: 175722

189601
type: SpeciesReference
stoichiometry: 1.0
species: 182154

189661
type: SpeciesReference
stoichiometry: 1.0
species: 181558

189637
type: SpeciesReference
stoichiometry: 1.0
species: 175614

189589
type: SpeciesReference
stoichiometry: 1.0
species: 168678

168678
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: coumarin_C9H6O2

189625
type: SpeciesReference
stoichiometry: 1.0
species: 181631

175385
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Reduced glutathione_C10H16N3O6S

185981
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: starch, structure 1 (1,6-{7[1,4-Glc], 4[1,4-Glc]})_C66H112O56

188068
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Uridine_C9H12N2O6

952627
type: Reaction
reactant: 259294
name: L-ascorbate transport via proton symport
product: 259331
notes: R_ASCBt4 subsystem: Transport, Extracellular R_ASCBt4 equation: ascb-L[e] + na1[e] <==> ascb-L[c] + na1[c]
is: ENSMUSG00000024354.4
product: 259318
is: ENSMUSG00000029847.6
reversible: true
is: ENSMUSG00000027340.7
reactant: 259306
fast: false

259294
type: SpeciesReference
stoichiometry: 1.0
species: 181389

259331
type: SpeciesReference
stoichiometry: 1.0
species: 166772

166772
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Ascorbate_C6H8O6

259318
type: SpeciesReference
stoichiometry: 1.0
species: 181377

259306
type: SpeciesReference
stoichiometry: 1.0
species: 166784

167049
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Betaine aldehyde_C5H12NO

945597
type: Reaction
is: ENSMUSG00000048550.8
reactant: 192908
product: 192932
product: 192944
name: threonine synthase
reversible: false
is: http://identifiers.org/ec-code/4.2.3.1
notes: R_THRS subsystem: Glycine, Serine, and Threonine Metabolism R_THRS equation: [c] : h2o + phom --> pi + thr-L
fast: false
reactant: 192920

192908
type: SpeciesReference
stoichiometry: 1.0
species: 175614

192932
type: SpeciesReference
stoichiometry: 1.0
species: 186936

186936
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Threonine_C4H9NO3

192944
type: SpeciesReference
stoichiometry: 1.0
species: 183652

192920
type: SpeciesReference
stoichiometry: 1.0
species: 183556

183556
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: O-Phospho-L-homoserine_C4H8NO6P

952795
type: Reaction
product: 261009
name: galactokinase
reversible: false
is: http://identifiers.org/ec-code/2.7.1.6
notes: R_GALK subsystem: Galactose metabolism R_GALK equation: [c] : atp + gal --> adp + gal1p + h
reactant: 260985
is: ENSMUSG00000020766.3
is: ENSMUSG00000027207.6
fast: false
product: 261021
reactant: 260997
product: 261034

261009
type: SpeciesReference
stoichiometry: 1.0
species: 173570

173570
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: alpha-D-Galactose 1-phosphate_C6H11O9P

260985
type: SpeciesReference
stoichiometry: 1.0
species: 166904

261021
type: SpeciesReference
stoichiometry: 1.0
species: 165387

260997
type: SpeciesReference
stoichiometry: 1.0
species: 173583

261034
type: SpeciesReference
stoichiometry: 1.0
species: 175722

946795
type: Reaction
reversible: false
notes: R_GASNASE2ly subsystem: N-Glycan Degradation R_GASNASE2ly equation: [l] : h2o + n2m2nmasn --> Asn-X-Ser/Thr + n2m2nm R_GASNASE3ly subsystem: Keratan sulfate degradation R_GASNASE3ly equation: [l] : h2o + ksi_deg1 --> Asn-X-Ser/Thr + ksi_deg2 R_GASNASEly subsystem: N-Glycan Degradation R_GASNASEly equation: [l] : h2o + s2l2n2m2masn --> Asn-X-Ser/Thr + s2l2n2m2m
product: 203616
reactant: 203579
is: http://identifiers.org/ec-code/3.5.1.26
reactant: 203592
product: 203640
product: 203628
product: 203604
fast: false
is: ENSMUSG00000031521.3
reactant: 203567
reactant: 203555

203616
type: SpeciesReference
stoichiometry: 3.0
species: 163703

163703
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: protein-linked asparagine residue (N-glycosylation site)_XH

203579
type: SpeciesReference
stoichiometry: 3.0
species: 175650

203592
type: SpeciesReference
stoichiometry: 1.0
species: 177712

177712
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 1_C241H383N17O209S12X

203640
type: SpeciesReference
stoichiometry: 1.0
species: 185205

185205
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: de-Fuc form of PA6 (w/o peptide linkage)_C84H136N6O62

203628
type: SpeciesReference
stoichiometry: 1.0
species: 177845

177845
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 2_C241H384N17O210S12

203604
type: SpeciesReference
stoichiometry: 1.0
species: 181262

181262
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: n2m2nmasn (w/o peptide linkage)_C58H97N5O41

203567
type: SpeciesReference
stoichiometry: 1.0
species: 185229

185229
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: de-Fuc form of PA6_C84H135N6O61X

203555
type: SpeciesReference
stoichiometry: 1.0
species: 181288

181288
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-(N-acetyl-beta-D-glucosaminyl-1,4)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R_C58H96N5O40X

182334
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: _9-O-Acetylated GD3 (homo sapiens)_C54H90N3O29FULLRCO

180016
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (alpha-D-Mannosyl)4-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1485H2440N20O420P20

949969
type: Reaction
product: 231886
product: 231910
notes: R_DHCR243r subsystem: Cholesterol Metabolism R_DHCR243r equation: [r] : dsmsterol + fadh2 --> chsterol + fad R_DHCR242r subsystem: Cholesterol Metabolism R_DHCR242r equation: [r] : chlstol + fadh2 --> fad + lthstrl R_DHCR241r subsystem: Cholesterol Metabolism R_DHCR241r equation: [r] : fadh2 + zymst --> fad + zymstnl
product: 231874
reactant: 231862
reactant: 231850
reactant: 231826
fast: false
reversible: false
is: ENSMUSG00000034926.3
reactant: 231838
product: 231898

231886
type: SpeciesReference
stoichiometry: 3.0
species: 172511

172511
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

231910
type: SpeciesReference
stoichiometry: 1.0
species: 188802

188802
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Zymostenol_C27H46O

231874
type: SpeciesReference
stoichiometry: 1.0
species: 179823

179823
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _5alpha-Cholest-7-en-3beta-ol_C27H46O

231862
type: SpeciesReference
stoichiometry: 1.0
species: 167784

231850
type: SpeciesReference
stoichiometry: 3.0
species: 172559

172559
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2

231826
type: SpeciesReference
stoichiometry: 1.0
species: 171547

171547
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Desmosterol_C27H44O

231838
type: SpeciesReference
stoichiometry: 1.0
species: 188790

231898
type: SpeciesReference
stoichiometry: 1.0
species: 168076

168076
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Cholesterol_C27H46O

947120
type: Reaction
reactant: 206753
product: 206777
is: ENSMUSG00000030376.5
fast: false
is: ENSMUSG00000079055.1
reversible: true
product: 206765
reactant: 206741
is: ENSMUSG00000054640.6
name: calcium / sodium antiporter (1:3), reversible
notes: R_CAt7r subsystem: Transport, Extracellular R_CAt7r equation: ca2[c] + (3) na1[e] <==> ca2[e] + (3) na1[c]

206753
type: SpeciesReference
stoichiometry: 3.0
species: 181389

206777
type: SpeciesReference
stoichiometry: 3.0
species: 181377

206765
type: SpeciesReference
stoichiometry: 1.0
species: 167471

206741
type: SpeciesReference
stoichiometry: 1.0
species: 167459

949283
type: Reaction
reactant: 225210
notes: R_NDPK9 subsystem: Nucleotides R_NDPK9 equation: [c] : atp + idp <==> adp + itp R_NDPK6n subsystem: Nucleotides R_NDPK6n equation: [n] : atp + dudp <==> adp + dutp R_NDPK8n subsystem: Nucleotides R_NDPK8n equation: [n] : atp + dadp <==> adp + datp R_NDPK3n subsystem: Nucleotides R_NDPK3n equation: [n] : atp + cdp <==> adp + ctp R_NDPK7n subsystem: Nucleotides R_NDPK7n equation: [n] : atp + dcdp <==> adp + dctp R_NDPK8 subsystem: Nucleotides R_NDPK8 equation: [c] : atp + dadp <==> adp + datp R_NDPK2 subsystem: Nucleotides R_NDPK2 equation: [c] : atp + udp <==> adp + utp R_NDPK6 subsystem: Nucleotides R_NDPK6 equation: [c] : atp + dudp <==> adp + dutp R_NDPK2n subsystem: Nucleotides R_NDPK2n equation: [n] : atp + udp <==> adp + utp R_NDPK5 subsystem: Nucleotides R_NDPK5 equation: [c] : atp + dgdp <==> adp + dgtp R_NDPK3 subsystem: Nucleotides R_NDPK3 equation: [c] : atp + cdp <==> adp + ctp R_NDPK4 subsystem: Nucleotides R_NDPK4 equation: [c] : atp + dtdp <==> adp + dttp R_NDPK10n subsystem: Nucleotides R_NDPK10n equation: [n] : atp + didp <==> adp + ditp R_NDPK1 subsystem: Nucleotides R_NDPK1 equation: [c] : atp + gdp <==> adp + gtp R_NDPK7 subsystem: Nucleotides R_NDPK7 equation: [c] : atp + dcdp <==> adp + dctp R_NDPK10 subsystem: Nucleotides R_NDPK10 equation: [c] : atp + didp <==> adp + ditp R_NDPK4n subsystem: Nucleotides R_NDPK4n equation: [n] : atp + dtdp <==> adp + dttp R_NDPK9n subsystem: Nucleotides R_NDPK9n equation: [n] : atp + idp <==> adp + itp R_NDPK5n subsystem: Nucleotides R_NDPK5n equation: [n] : atp + dgdp <==> adp + dgtp R_NDPK1n subsystem: Nucleotides R_NDPK1n equation: [n] : atp + gdp <==> adp + gtp
product: 225452
product: 225536
reactant: 225258
product: 225427
reactant: 225306
product: 225621
reactant: 225234
is: ENSMUSG00000020857.4
reactant: 225198
product: 225633
is: ENSMUSG00000037601.3
product: 225403
product: 225464
reactant: 225138
product: 225415
reactant: 225174
product: 225440
product: 225500
reactant: 225150
product: 225597
fast: false
reactant: 225282
is: ENSMUSG00000080002.1
product: 225609
reactant: 225343
product: 225512
reactant: 225367
reactant: 225186
product: 225476
product: 225391
reactant: 225222
reactant: 225126
is: http://identifiers.org/ec-code/2.7.4.6
reactant: 225162
reactant: 225294
product: 225645
product: 225560
reactant: 225318
product: 225488
reactant: 225246
reactant: 225270
product: 225548
reactant: 225330
product: 225573
reactant: 225379
product: 225524
product: 225585
reversible: true
reactant: 225355

225210
type: SpeciesReference
stoichiometry: 1.0
species: 171716

225452
type: SpeciesReference
stoichiometry: 1.0
species: 188128

225536
type: SpeciesReference
stoichiometry: 1.0
species: 170532

225258
type: SpeciesReference
stoichiometry: 1.0
species: 169865

225427
type: SpeciesReference
stoichiometry: 1.0
species: 169641

169641
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: CTP_C9H12N3O14P3

225306
type: SpeciesReference
stoichiometry: 1.0
species: 187584

225621
type: SpeciesReference
stoichiometry: 1.0
species: 169615

225234
type: SpeciesReference
stoichiometry: 1.0
species: 167675

167675
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: CDP_C9H12N3O11P2

225198
type: SpeciesReference
stoichiometry: 1.0
species: 169841

225633
type: SpeciesReference
stoichiometry: 1.0
species: 188092

225403
type: SpeciesReference
stoichiometry: 1.0
species: 171824

225464
type: SpeciesReference
stoichiometry: 1.0
species: 169951

225138
type: SpeciesReference
stoichiometry: 1.0
species: 170918

170918
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: dIDP_C10H11N4O10P2

225415
type: SpeciesReference
stoichiometry: 1.0
species: 177507

177507
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: ITP_C10H11N4O14P3

225174
type: SpeciesReference
stoichiometry: 1.0
species: 174118

225440
type: SpeciesReference
stoichiometry: 1.0
species: 171680

225500
type: SpeciesReference
stoichiometry: 1.0
species: 169975

169975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: dATP_C10H12N5O12P3

225150
type: SpeciesReference
stoichiometry: 1.0
species: 174166

174166
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: GDP_C10H12N5O11P2

225597
type: SpeciesReference
stoichiometry: 1.0
species: 170181

225282
type: SpeciesReference
stoichiometry: 1.0
species: 171740

171740
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: dUDP_C9H11N2O11P2

225609
type: SpeciesReference
stoichiometry: 1.0
species: 171027

171027
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: dITP_C10H11N4O13P3

225343
type: SpeciesReference
stoichiometry: 1.0
species: 170024

225512
type: SpeciesReference
stoichiometry: 10.0
species: 165387

225367
type: SpeciesReference
stoichiometry: 1.0
species: 170411

225186
type: SpeciesReference
stoichiometry: 10.0
species: 166904

225476
type: SpeciesReference
stoichiometry: 1.0
species: 171704

171704
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: dTTP_C10H13N2O14P3

225391
type: SpeciesReference
stoichiometry: 1.0
species: 170556

170556
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: dGTP_C10H12N5O13P3

225222
type: SpeciesReference
stoichiometry: 1.0
species: 171571

225126
type: SpeciesReference
stoichiometry: 1.0
species: 170894

225162
type: SpeciesReference
stoichiometry: 1.0
species: 177205

225294
type: SpeciesReference
stoichiometry: 1.0
species: 177167

225645
type: SpeciesReference
stoichiometry: 1.0
species: 177483

225560
type: SpeciesReference
stoichiometry: 1.0
species: 171003

225318
type: SpeciesReference
stoichiometry: 1.0
species: 171595

225488
type: SpeciesReference
stoichiometry: 1.0
species: 170206

170206
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: dCTP_C9H12N3O13P3

225246
type: SpeciesReference
stoichiometry: 1.0
species: 187645

225270
type: SpeciesReference
stoichiometry: 1.0
species: 170049

170049
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: dCDP_C9H12N3O10P2

225548
type: SpeciesReference
stoichiometry: 10.0
species: 165423

225330
type: SpeciesReference
stoichiometry: 10.0
species: 166940

225573
type: SpeciesReference
stoichiometry: 1.0
species: 171848

171848
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: dUTP_C9H11N2O14P3

225379
type: SpeciesReference
stoichiometry: 1.0
species: 167651

225524
type: SpeciesReference
stoichiometry: 1.0
species: 175434

225585
type: SpeciesReference
stoichiometry: 1.0
species: 175470

175470
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: GTP_C10H12N5O14P3

225355
type: SpeciesReference
stoichiometry: 1.0
species: 170435

170435
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: dGDP_C10H12N5O10P2

955103
type: Reaction
is: ENSMUSG00000068221.3
notes: R_PGLYCP subsystem: Glyoxylate and Dicarboxylate Metabolism R_PGLYCP equation: [c] : 2pglyc + h2o --> glyclt + pi
reactant: 282719
is: ENSMUSG00000043445.6
is: http://identifiers.org/ec-code/3.1.3.18
product: 282731
fast: false
reactant: 282707
product: 282743
name: Phosphoglycolate phosphatase
reversible: false

282719
type: SpeciesReference
stoichiometry: 1.0
species: 161526

161526
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _2-Phosphoglycolate_C2H2O6P

282731
type: SpeciesReference
stoichiometry: 1.0
species: 174805

282707
type: SpeciesReference
stoichiometry: 1.0
species: 175614

282743
type: SpeciesReference
stoichiometry: 1.0
species: 183652

952555
type: Reaction
is: ENSMUSG00000028854.6
product: 258681
reactant: 258633
notes: R_NAt5 subsystem: Transport, Extracellular R_NAt5 equation: na1[c] + nh4[e] <==> na1[e] + nh4[c] R_NAt3_1 subsystem: Transport, Extracellular R_NAt3_1 equation: h[e] + na1[c] <==> h[c] + na1[e]
is: ENSMUSG00000036123.6
fast: false
product: 258669
reversible: true
product: 258693
is: ENSMUSG00000026062.6
reactant: 258657
reactant: 258645

258681
type: SpeciesReference
stoichiometry: 1.0
species: 181752

258633
type: SpeciesReference
stoichiometry: 1.0
species: 175734

258669
type: SpeciesReference
stoichiometry: 2.0
species: 181389

258693
type: SpeciesReference
stoichiometry: 1.0
species: 175722

258657
type: SpeciesReference
stoichiometry: 2.0
species: 181377

258645
type: SpeciesReference
stoichiometry: 1.0
species: 181764

181764
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Ammonium_H4N

955595
type: Reaction
is: http://identifiers.org/ec-code/2.5.1.21
fast: false
is: ENSMUSG00000021273.8
product: 288987
reactant: 288951
reversible: false
notes: R_SQLSr subsystem: Cholesterol Metabolism R_SQLSr equation: [r] : (2) frdp + h + nadph --> nadp + (2) ppi + sql
reactant: 288939
product: 288975
reactant: 288963
product: 288999
name: Squalene synthase

288987
type: SpeciesReference
stoichiometry: 1.0
species: 185885

185885
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Squalene_C30H50

288951
type: SpeciesReference
stoichiometry: 1.0
species: 181667

288939
type: SpeciesReference
stoichiometry: 2.0
species: 172908

172908
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Farnesyl diphosphate_C15H25O7P2

288975
type: SpeciesReference
stoichiometry: 2.0
species: 183953

183953
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Diphosphate_HO7P2

288963
type: SpeciesReference
stoichiometry: 1.0
species: 175794

288999
type: SpeciesReference
stoichiometry: 1.0
species: 181607

164210
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: R total carnitine_CO2FULLRC7H14NO2

180463
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Maltotriose_C18H32O16

185386
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Se-Adenosylselenomethionine_C15H23N6O5Se

185873
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Spermine_C10H30N4

951437
type: Reaction
fast: false
product: 246046
is: ENSMUSG00000062070.5
is: ENSMUSG00000056050.4
reactant: 246022
name: phosphoglycerate kinase
reversible: true
reactant: 246034
notes: R_PGK subsystem: Glycolysis/Gluconeogenesis R_PGK equation: [c] : 3pg + atp <==> 13dpg + adp
product: 246058
is: http://identifiers.org/ec-code/2.7.2.3
is: ENSMUSG00000031233.4

246046
type: SpeciesReference
stoichiometry: 1.0
species: 165387

246022
type: SpeciesReference
stoichiometry: 1.0
species: 166904

246034
type: SpeciesReference
stoichiometry: 1.0
species: 162242

246058
type: SpeciesReference
stoichiometry: 1.0
species: 160968

160968
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Phospho-D-glyceroyl phosphate_C3H4O10P2

178425
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 33_C233H372N16O197S10X

953913
type: Reaction
product: 271136
reversible: false
reactant: 271088
fast: false
reactant: 271051
product: 271160
reactant: 271076
notes: R_GLYVESSEC subsystem: Transport, Extracellular R_GLYVESSEC equation: atp[c] + (3) gly[c] + h2o[c] --> adp[c] + (3) gly[e] + h[c] + pi[c] R_BALAVECSEC subsystem: Transport, Extracellular R_BALAVECSEC equation: (3) ala-B[c] + atp[c] + h2o[c] --> adp[c] + (3) ala-B[e] + h[c] + pi[c] R_GABAVESSEC subsystem: Transport, Extracellular R_GABAVESSEC equation: (3) 4abut[c] + atp[c] + h2o[c] --> (3) 4abut[e] + adp[c] + h[c] + pi[c]
product: 271112
product: 271172
reactant: 271100
product: 271124
reactant: 271063
product: 271148
is: ENSMUSG00000037771.7

271136
type: SpeciesReference
stoichiometry: 3.0
species: 174637

174637
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Glycine_C2H5NO2

271088
type: SpeciesReference
stoichiometry: 3.0
species: 175614

271051
type: SpeciesReference
stoichiometry: 3.0
species: 162446

271160
type: SpeciesReference
stoichiometry: 3.0
species: 162459

271076
type: SpeciesReference
stoichiometry: 3.0
species: 166904

271112
type: SpeciesReference
stoichiometry: 3.0
species: 165943

165943
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: beta-Alanine_C3H7NO2

271172
type: SpeciesReference
stoichiometry: 3.0
species: 175722

271100
type: SpeciesReference
stoichiometry: 3.0
species: 165931

271124
type: SpeciesReference
stoichiometry: 3.0
species: 183652

271063
type: SpeciesReference
stoichiometry: 3.0
species: 174625

174625
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Glycine_C2H5NO2

271148
type: SpeciesReference
stoichiometry: 3.0
species: 165387

947913
type: Reaction
reactant: 213091
notes: R_TMDPP subsystem: Pyrimidine Catabolism R_TMDPP equation: [c] : pi + thymd <==> 2dr1p + thym
is: ENSMUSG00000022615.5
product: 213127
fast: false
reactant: 213103
product: 213115
reversible: true
name: thymidine phosphorylase
is: http://identifiers.org/ec-code/2.4.2.4

213091
type: SpeciesReference
stoichiometry: 1.0
species: 183652

213127
type: SpeciesReference
stoichiometry: 1.0
species: 161356

161356
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _2-Deoxy-D-ribose 1-phosphate_C5H9O7P

213103
type: SpeciesReference
stoichiometry: 1.0
species: 186984

213115
type: SpeciesReference
stoichiometry: 1.0
species: 186960

176553
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 18_C43H66N2O45S3

171920
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: epiandrosterone_C19H28O3

955788
type: Reaction
is: ENSMUSG00000021259.4
reactant: 290929
product: 290965
reactant: 290905
reactant: 290917
fast: false
product: 290941
name: cytochrome P450, family 46, subfamily A, polypeptide 1
reactant: 290893
product: 290953
reversible: false
notes: R_P45046A1r subsystem: Bile Acid Biosynthesis R_P45046A1r equation: [r] : chsterol + h + nadph + o2 --> h2o + nadp + xol24oh

290929
type: SpeciesReference
stoichiometry: 1.0
species: 175794

290965
type: SpeciesReference
stoichiometry: 1.0
species: 181607

290905
type: SpeciesReference
stoichiometry: 1.0
species: 168076

290917
type: SpeciesReference
stoichiometry: 1.0
species: 181667

290941
type: SpeciesReference
stoichiometry: 1.0
species: 188358

188358
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _24-Hydroxycholesterol_C27H46O2

290893
type: SpeciesReference
stoichiometry: 1.0
species: 182202

290953
type: SpeciesReference
stoichiometry: 1.0
species: 175686

955271
type: Reaction
modifier: 284206
product: 284170
is: ENSMUSG00000029482.2
modifier: 284230
modifier: 284218
product: 284145
is: http://identifiers.org/ec-code/6.2.1.16
is: http://identifiers.org/ec-code/6.2.1.1
modifier: 284242
reactant: 284097
fast: false
reactant: 284109
product: 284182
modifier: 284255
product: 284158
modifier: 284194
reversible: false
reactant: 284121
notes: R_AACOAT subsystem: Propanoate Metabolism R_AACOAT equation: [c] : acac + atp + coa <==> aacoa + amp + ppi R_ACS2 subsystem: Propanoate Metabolism R_ACS2 equation: [c] : atp + coa + ppa --> amp + ppcoa + ppi R_ACS subsystem: Glycolysis/Gluconeogenesis R_ACS equation: [c] : ac + atp + coa --> accoa + amp + ppi
reactant: 284133

284170
type: SpeciesReference
stoichiometry: 2.0
species: 166219

164486
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Acetoacetate_C4H5O3

164366
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Acetoacetyl-CoA_C25H36N7O18P3S

284145
type: SpeciesReference
stoichiometry: 1.0
species: 183880

284097
type: SpeciesReference
stoichiometry: 2.0
species: 168509

284109
type: SpeciesReference
stoichiometry: 1.0
species: 164438

284182
type: SpeciesReference
stoichiometry: 2.0
species: 183917

284158
type: SpeciesReference
stoichiometry: 1.0
species: 164583

284121
type: SpeciesReference
stoichiometry: 2.0
species: 166904

284133
type: SpeciesReference
stoichiometry: 1.0
species: 183844

946422
type: Reaction
notes: R_CAATPS subsystem: Transport, Extracellular R_CAATPS equation: atp[c] + (2) ca2[c] + h2o[c] --> adp[c] + (2) ca2[e] + h[e] + pi[c]
is: http://identifiers.org/ec-code/3.6.3.6
product: 199596
reactant: 199536
reactant: 199560
product: 199584
reversible: false
is: ENSMUSG00000032826.7
is: ENSMUSG00000078761.1
fast: false
is: ENSMUSG00000078137.1
product: 199608
is: ENSMUSG00000030302.7
reactant: 199548
is: ENSMUSG00000019943.7
is: ENSMUSG00000031376.6
product: 199572
name: Ca ATPase

199596
type: SpeciesReference
stoichiometry: 1.0
species: 175734

199536
type: SpeciesReference
stoichiometry: 2.0
species: 167459

199560
type: SpeciesReference
stoichiometry: 1.0
species: 166904

199584
type: SpeciesReference
stoichiometry: 2.0
species: 167471

199608
type: SpeciesReference
stoichiometry: 1.0
species: 183652

199548
type: SpeciesReference
stoichiometry: 1.0
species: 175614

199572
type: SpeciesReference
stoichiometry: 1.0
species: 165387

181425
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Nicotinate_C6H4NO2

952507
type: Reaction
is: http://identifiers.org/ec-code/1.4.3.6
reactant: 257975
reactant: 257890
reactant: 257951
reactant: 257914
reactant: 257854
fast: false
product: 258047
product: 258083
product: 258023
product: 258143
product: 258119
reactant: 257866
product: 258131
product: 258107
reversible: false
reactant: 257939
notes: R_3MOXTYROX subsystem: Tyrosine metabolism R_3MOXTYROX equation: [c] : 3moxtyr + h2o + o2 --> 3mox4hpac + h2o2 + nh4 R_MAOLNOR subsystem: Tyrosine metabolism R_MAOLNOR equation: [c] : h2o + normete-L + o2 --> 3m4hpga + h2o2 + nh4 R_APRTO2 subsystem: Arginine and Proline Metabolism R_APRTO2 equation: [c] : aprut + h2o + o2 --> h2o2 + n4abutn + nh4 R_42A12BOOX subsystem: Tyrosine metabolism R_42A12BOOX equation: [c] : dopa + h2o + o2 --> 34dhpac + h2o2 + nh4 R_PEAMNO subsystem: Phenylalanine metabolism R_PEAMNO equation: [c] : h2o + o2 + peamn --> h2o2 + nh4 + pacald R_3HXKYNOXDA subsystem: Tryptophan metabolism R_3HXKYNOXDA equation: [c] : 3hxkynam + o2 --> 48dhoxquin + h2o2 + nh4 R_41R2A1H12BOOX subsystem: Tyrosine metabolism R_41R2A1H12BOOX equation: [c] : h2o + nrpphr + o2 --> 34dhmald + h2o2 + nh4 R_TRYPTAOX subsystem: Tryptophan metabolism R_TRYPTAOX equation: [c] : h2o + o2 + trypta --> h2o2 + id3acald + nh4 R_5HXKYNOXDA subsystem: Tryptophan metabolism R_5HXKYNOXDA equation: [c] : 5hxkynam + o2 --> 46dhoxquin + h2o2 + nh4 R_TYROXDAc subsystem: Tyrosine metabolism R_TYROXDAc equation: [c] : h2o + o2 + tym --> 4hoxpacd + h2o2 + nh4 R_5HOXINOXDA subsystem: Tryptophan metabolism R_5HOXINOXDA equation: [c] : h2o + o2 + srtn --> 5hoxindact + h2o2 + nh4 R_41R1H2MAE12BOOX subsystem: Tyrosine metabolism R_41R1H2MAE12BOOX equation: [c] : adrnl + h2o + o2 --> 34dhmald + h2o2 + mma
reactant: 258011
reactant: 257902
reactant: 257987
is: http://identifiers.org/ec-code/1.4.3.4
product: 258071
reactant: 257999
reactant: 257878
reactant: 257927
product: 258179
product: 258167
reactant: 257963
product: 258155
product: 258095
product: 258059
product: 258035
is: ENSMUSG00000025037.5

257975
type: SpeciesReference
stoichiometry: 1.0
species: 171451

257890
type: SpeciesReference
stoichiometry: 1.0
species: 187308

257951
type: SpeciesReference
stoichiometry: 1.0
species: 185897

257914
type: SpeciesReference
stoichiometry: 1.0
species: 162144

257854
type: SpeciesReference
stoichiometry: 1.0
species: 182008

258047
type: SpeciesReference
stoichiometry: 1.0
species: 162592

258083
type: SpeciesReference
stoichiometry: 1.0
species: 181078

258023
type: SpeciesReference
stoichiometry: 1.0
species: 162132

258143
type: SpeciesReference
stoichiometry: 1.0
species: 177119

258119
type: SpeciesReference
stoichiometry: 1.0
species: 182827

257866
type: SpeciesReference
stoichiometry: 1.0
species: 181984

258131
type: SpeciesReference
stoichiometry: 12.0
species: 175542

258107
type: SpeciesReference
stoichiometry: 1.0
species: 163136

257939
type: SpeciesReference
stoichiometry: 1.0
species: 163233

258011
type: SpeciesReference
stoichiometry: 1.0
species: 166495

257902
type: SpeciesReference
stoichiometry: 1.0
species: 187500

257987
type: SpeciesReference
stoichiometry: 10.0
species: 175614

258071
type: SpeciesReference
stoichiometry: 11.0
species: 181752

257999
type: SpeciesReference
stoichiometry: 12.0
species: 182154

257878
type: SpeciesReference
stoichiometry: 1.0
species: 165629

257927
type: SpeciesReference
stoichiometry: 1.0
species: 183349

258179
type: SpeciesReference
stoichiometry: 1.0
species: 162398

258167
type: SpeciesReference
stoichiometry: 2.0
species: 161551

257963
type: SpeciesReference
stoichiometry: 1.0
species: 161987

258155
type: SpeciesReference
stoichiometry: 1.0
species: 162410

258095
type: SpeciesReference
stoichiometry: 1.0
species: 162011

258059
type: SpeciesReference
stoichiometry: 1.0
species: 161587

258035
type: SpeciesReference
stoichiometry: 1.0
species: 181340

179461
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: (R)-S-Lactoylglutathione_C13H20N3O8S

954730
type: Reaction
is: ENSMUSG00000051483.7
reversible: false
notes: R_CBR2 subsystem: Eicosanoid Metabolism R_CBR2 equation: [c] : h + nadph + prostge2 --> nadp + prostgf2 R_CBR1 subsystem: Eicosanoid Metabolism R_CBR1 equation: [c] : h + nadph + prostg1 --> nadp + prostge1
reactant: 279178
product: 279202
reactant: 279154
reactant: 279190
reactant: 279166
fast: false
product: 279226
product: 279214

279178
type: SpeciesReference
stoichiometry: 2.0
species: 175722

279202
type: SpeciesReference
stoichiometry: 1.0
species: 184435

184435
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Prostaglandin E1_C20H33O5

279154
type: SpeciesReference
stoichiometry: 1.0
species: 184459

279190
type: SpeciesReference
stoichiometry: 2.0
species: 181631

279166
type: SpeciesReference
stoichiometry: 1.0
species: 184386

184386
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: (13E)-11alpha-Hydroxy-9,15-dioxoprost-13-enoate_C20H31O5

279226
type: SpeciesReference
stoichiometry: 2.0
species: 181558

279214
type: SpeciesReference
stoichiometry: 1.0
species: 184495

948730
type: Reaction
reversible: false
reactant: 220052
name: gamma-glutamylcyclotransferase
is: http://identifiers.org/ec-code/2.3.2.4
product: 220064
fast: false
notes: R_GGLUCT subsystem: Glutathione Metabolism R_GGLUCT equation: gluala[e] --> 5oxpro[c] + ala-L[c]
is: ENSMUSG00000002797.6
product: 220076

220052
type: SpeciesReference
stoichiometry: 1.0
species: 174503

174503
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: _5-L-Glutamyl-L-alanine_C8H13N2O5

220064
type: SpeciesReference
stoichiometry: 1.0
species: 163305

163305
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-Oxoproline_C5H6NO3

220076
type: SpeciesReference
stoichiometry: 1.0
species: 166015

170338
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: debrisoquine_C10H14N3

163751
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-2-Aminoadipate_C6H10NO4

185145
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Ribulose 5-phosphate_C5H9O8P

173826
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: galactocerebroside (homo sapiens)_C24H46NO7FULLRCO

174781
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Glycerol_C3H8O3

172848
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Formimidoyl-L-glutamate_C6H8N2O4

187464
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: tetradecanoyl carnitine_C21H41NO4

165209
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: O-Acetylcarnitine_C9H17NO4

173449
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1905H3140N20O770P20

183446
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: phosphatidylglycerol (homo sapiens)_C6H12O6PFULLRCO2FULLR2CO2

182106
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Nervonyl carnitine_C31H59NO4

176987
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Hypoxanthine_C5H4N4O

946120
type: Reaction
reversible: true
product: 197492
notes: R_CSNAT2x subsystem: Fatty Acid Metabolism R_CSNAT2x equation: [x] : crn + dmnoncoa <==> coa + dmnoncrn
reactant: 197468
fast: false
is: http://identifiers.org/ec-code/2.3.1.7
product: 197504
is: ENSMUSG00000003623.3
reactant: 197480
name: carnitine dimethyl nonanoyl transferase, revsible, peroxisomal

197492
type: SpeciesReference
stoichiometry: 1.0
species: 168581

197468
type: SpeciesReference
stoichiometry: 1.0
species: 171172

197504
type: SpeciesReference
stoichiometry: 1.0
species: 171184

171184
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: _4,8 dimethylnonanoyl carnitine_C18H37NO4

197480
type: SpeciesReference
stoichiometry: 1.0
species: 168848

168848
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: L-Carnitine_C7H15NO3

178317
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 25_C199H319N14O163S7X

953073
type: Reaction
reactant: 263967
product: 263991
notes: R_GBGT1 subsystem: Sphingolipid Metabolism R_GBGT1 equation: [g] : gbside_hs + udpacgal --> acgagbside_hs + h + udp
fast: false
is: ENSMUSG00000026829.1
reactant: 263979
product: 264003
name: globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
reversible: false
product: 264015

263967
type: SpeciesReference
stoichiometry: 1.0
species: 173923

173923
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: globoside (homo sapiens)_C44H79N2O22FULLRCO

263991
type: SpeciesReference
stoichiometry: 1.0
species: 164727

164727
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: alpha GalNAc globoside (homo sapiens)_C52H92N3O27FULLRCO

263979
type: SpeciesReference
stoichiometry: 1.0
species: 187681

264003
type: SpeciesReference
stoichiometry: 1.0
species: 187608

264015
type: SpeciesReference
stoichiometry: 1.0
species: 175746

950114
type: Reaction
reactant: 234806
reactant: 234758
reactant: 234794
is: ENSMUSG00000042042.7
product: 234915
reactant: 234830
reactant: 234818
is: ENSMUSG00000036356.6
product: 234903
product: 234890
notes: R_GALNACT1g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT1g equation: [g] : cs,hs_linkage + udpacgal --> cs_pre + h + udp R_GALNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT5g equation: [g] : cs_e_pre3 + uacgam --> cs_e_pre4 + h + udp R_GALNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT4g equation: [g] : cs_d_pre3 + uacgam --> cs_d_pre4 + h + udp R_GALNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT3g equation: [g] : cs_c_pre2 + uacgam --> cs_c_pre3 + h + udp R_GALNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT2g equation: [g] : cs_a,b_pre2 + uacgam --> cs_a,b_pre3 + h + udp
product: 234866
reversible: false
product: 234854
product: 234842
is: http://identifiers.org/ec-code/2.4.1.174
fast: false
product: 234878
reactant: 234782
reactant: 234770
is: http://identifiers.org/ec-code/2.4.1.175

234806
type: SpeciesReference
stoichiometry: 1.0
species: 187681

234758
type: SpeciesReference
stoichiometry: 1.0
species: 169321

169321
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 3_C37H53NO40S3X

234794
type: SpeciesReference
stoichiometry: 1.0
species: 169467

169467
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 3_C37H52NO43S4X

234915
type: SpeciesReference
stoichiometry: 1.0
species: 169516

169516
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate precursor (GalNAc-GlcA-(Gal)2-Xyl-L-Ser (protein))_C31H49NO25X

234830
type: SpeciesReference
stoichiometry: 1.0
species: 168944

168944
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate A (GalNAc4S-GlcA) and B (IdoA2S-GalNAc4S), precursor 2_C37H54NO37S2X

234818
type: SpeciesReference
stoichiometry: 1.0
species: 168920

168920
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate/heparan sulfate linkage region (GlcA-(Gal)2-Xyl-L-Ser (protein))_C23H36O20X

234903
type: SpeciesReference
stoichiometry: 1.0
species: 169479

169479
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 4_C45H65N2O48S4X

234890
type: SpeciesReference
stoichiometry: 1.0
species: 168958

168958
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate A (GalNAc4S-GlcA) and B (IdoA2S-GalNAc4S), precursor 3_C45H67N2O42S2X

234866
type: SpeciesReference
stoichiometry: 5.0
species: 175746

234854
type: SpeciesReference
stoichiometry: 5.0
species: 187608

234842
type: SpeciesReference
stoichiometry: 1.0
species: 169333

169333
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 4_C45H66N2O45S3X

234878
type: SpeciesReference
stoichiometry: 1.0
species: 169212

234782
type: SpeciesReference
stoichiometry: 4.0
species: 187572

234770
type: SpeciesReference
stoichiometry: 1.0
species: 169200

169200
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate C (GalNAc6S-GlcA), precursor 2_C37H54NO37S2X

165641
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Adrenaline_C9H14NO3

173041
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: L-Fucose_C6H12O5

949777
type: Reaction
reactant: 229641
reactant: 229604
is: http://identifiers.org/ec-code/3.2.1.1
product: 229690
product: 229653
fast: false
reactant: 229629
product: 229678
product: 229702
reactant: 229592
notes: R_AMY1e subsystem: Starch and Sucrose Metabolism R_AMY1e equation: [e] : (8) h2o + strch1 --> (8) glc-D + strch2 R_CYSTSERex subsystem: Transport, Extracellular R_CYSTSERex equation: Lcystin[e] + ser-L[c] --> Lcystin[c] + ser-L[e] R_AMY2e subsystem: Starch and Sucrose Metabolism R_AMY2e equation: [e] : glygn2 + (8) h2o --> (8) glc-D + glygn4
product: 229665
is: ENSMUSG00000030492.8
reversible: false
reactant: 229616

229641
type: SpeciesReference
stoichiometry: 1.0
species: 174865

174865
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]})_C66H111O56X

229604
type: SpeciesReference
stoichiometry: 1.0
species: 185532

229690
type: SpeciesReference
stoichiometry: 1.0
species: 185544

185544
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Serine_C3H7NO3

229653
type: SpeciesReference
stoichiometry: 1.0
species: 163799

163799
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Cystine_C6H12N2O4S2

229629
type: SpeciesReference
stoichiometry: 1.0
species: 185981

229678
type: SpeciesReference
stoichiometry: 1.0
species: 185993

229702
type: SpeciesReference
stoichiometry: 1.0
species: 174889

229592
type: SpeciesReference
stoichiometry: 1.0
species: 163811

163811
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Cystine_C6H12N2O4S2

229665
type: SpeciesReference
stoichiometry: 16.0
species: 174286

229616
type: SpeciesReference
stoichiometry: 16.0
species: 175626

949451
type: Reaction
is: ENSMUSG00000027809.6
product: 227227
is: http://identifiers.org/ec-code/1.5.5.1
fast: false
reactant: 227191
reactant: 227203
name: Electron transfer flavoprotein-ubiquinone oxidoreductase
notes: R_ETFQO subsystem: Fatty acid oxidation R_ETFQO equation: [m] : etfrd + q10 --> etfox + q10h2
reversible: false
product: 227215

227227
type: SpeciesReference
stoichiometry: 1.0
species: 184903

227191
type: SpeciesReference
stoichiometry: 1.0
species: 172355

227203
type: SpeciesReference
stoichiometry: 1.0
species: 184879

227215
type: SpeciesReference
stoichiometry: 1.0
species: 172343

952723
type: Reaction
is: http://identifiers.org/ec-code/1.1.1.37
product: 260117
fast: false
product: 260093
product: 260129
reversible: true
reactant: 260057
notes: R_SLDx subsystem: Cysteine Metabolism R_SLDx equation: [c] : nad + sl-L <==> 3spyr + h + nadh R_MDH subsystem: Citric Acid Cycle R_MDH equation: [c] : mal-L + nad <==> h + nadh + oaa
is: ENSMUSG00000020321.8
is: ENSMUSG00000025963.3
is: http://identifiers.org/ec-code/1.1.1.272
reactant: 260081
reactant: 260069
product: 260105

260117
type: SpeciesReference
stoichiometry: 2.0
species: 175722

260093
type: SpeciesReference
stoichiometry: 1.0
species: 162314

260129
type: SpeciesReference
stoichiometry: 2.0
species: 181510

260057
type: SpeciesReference
stoichiometry: 2.0
species: 181437

260081
type: SpeciesReference
stoichiometry: 1.0
species: 185605

260069
type: SpeciesReference
stoichiometry: 1.0
species: 180355

180355
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Malate_C4H4O5

260105
type: SpeciesReference
stoichiometry: 1.0
species: 182286

182286
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Oxaloacetate_C4H2O5

171812
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Deoxyuridine_C9H12N2O5

187802
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: UDP-D-glucuronate_C15H19N2O18P2

950714
type: Reaction
name: sodium proton antiporter (H:NA is 1:1)
is: ENSMUSG00000026065.7
reactant: 239336
reversible: true
is: ENSMUSG00000059201.5
notes: R_NAt3_1 subsystem: Transport, Extracellular R_NAt3_1 equation: h[e] + na1[c] <==> h[c] + na1[e]
product: 239372
reactant: 239348
product: 239360
fast: false

239336
type: SpeciesReference
stoichiometry: 1.0
species: 175734

239372
type: SpeciesReference
stoichiometry: 1.0
species: 175722

239348
type: SpeciesReference
stoichiometry: 1.0
species: 181377

239360
type: SpeciesReference
stoichiometry: 1.0
species: 181389

952807
type: Reaction
reactant: 261118
product: 261238
product: 261263
reactant: 261142
product: 261166
reactant: 261046
is: ENSMUSG00000027198.5
product: 261251
reactant: 261130
fast: false
product: 261275
reactant: 261082
reactant: 261106
product: 261202
product: 261190
reactant: 261154
reactant: 261070
reactant: 261094
reactant: 261058
product: 261226
is: ENSMUSG00000061731.2
product: 261214
reversible: false
notes: R_GLCAT9g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT9g equation: [g] : hs_pre7 + udpglcur --> h + hs_pre8 + udp R_GLCAT6g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT6g equation: [g] : hs_pre1 + udpglcur --> h + hs_pre2 + udp R_GLCNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT2g equation: [g] : hs_pre2 + uacgam --> h + hs_pre3 + udp R_GLCAT8g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT8g equation: [g] : hs_pre5 + udpglcur --> h + hs_pre6 + udp R_GLCNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT5g equation: [g] : hs_pre8 + uacgam --> h + hs_pre9 + udp R_GLCNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT3g equation: [g] : hs_pre4 + uacgam --> h + hs_pre5 + udp R_GLCAT7g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT7g equation: [g] : hs_pre3 + udpglcur --> h + hs_pre4 + udp R_GLCNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT4g equation: [g] : hs_pre6 + uacgam --> h + hs_pre7 + udp
product: 261178

261118
type: SpeciesReference
stoichiometry: 1.0
species: 176926

176926
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: heparan sulfate, precursor 8_C79H116N4O64X

261238
type: SpeciesReference
stoichiometry: 1.0
species: 176926

261263
type: SpeciesReference
stoichiometry: 1.0
species: 176866

176866
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: heparan sulfate, precursor 3_C45H69N2O36X

261142
type: SpeciesReference
stoichiometry: 1.0
species: 176866

261166
type: SpeciesReference
stoichiometry: 1.0
species: 176938

261046
type: SpeciesReference
stoichiometry: 1.0
species: 176842

261251
type: SpeciesReference
stoichiometry: 1.0
species: 176914

261130
type: SpeciesReference
stoichiometry: 1.0
species: 176914

261275
type: SpeciesReference
stoichiometry: 1.0
species: 176902

176902
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: heparan sulfate, precursor 6_C65H96N3O53X

261082
type: SpeciesReference
stoichiometry: 4.0
species: 187789

187789
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: UDP-D-glucuronate_C15H19N2O18P2

261106
type: SpeciesReference
stoichiometry: 1.0
species: 176890

176890
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: heparan sulfate, precursor 5_C59H89N3O47X

261202
type: SpeciesReference
stoichiometry: 1.0
species: 176878

176878
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: heparan sulfate, precursor 4_C51H76N2O42X

261190
type: SpeciesReference
stoichiometry: 8.0
species: 175746

261154
type: SpeciesReference
stoichiometry: 1.0
species: 176902

261070
type: SpeciesReference
stoichiometry: 1.0
species: 176878

261094
type: SpeciesReference
stoichiometry: 1.0
species: 176854

176854
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: heparan sulfate, precursor 2_C37H56NO31X

261058
type: SpeciesReference
stoichiometry: 4.0
species: 187572

261226
type: SpeciesReference
stoichiometry: 1.0
species: 176890

261214
type: SpeciesReference
stoichiometry: 1.0
species: 176854

261178
type: SpeciesReference
stoichiometry: 8.0
species: 187608

177724
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 20_C138H223N9O119S6

163643
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: heptaglutamyl folate (THF)_C49H57N13O24

161318
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _2-Decaprenyl-6-methoxy-1,4-benzoquinone_C57H86O3

183592
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: _2-Hydroxyphytanoyl-CoA_C41H70N7O18P3S

947648
type: Reaction
reactant: 211282
reversible: false
reactant: 211234
product: 211380
product: 211331
reactant: 211246
product: 211306
product: 211344
is: ENSMUSG00000079135.1
is: ENSMUSG00000030711.6
fast: false
reactant: 211294
reactant: 211270
product: 211368
is: ENSMUSG00000029269.4
product: 211318
notes: R_DOPASULT subsystem: Tyrosine metabolism R_DOPASULT equation: [c] : dopa + paps --> dopasf + h + pap R_4NPHSULT subsystem: CYP Metabolism R_4NPHSULT equation: [c] : 4nph + paps --> 4nphsf + h + pap R_TRIODTHYSULT subsystem: Tyrosine metabolism R_TRIODTHYSULT equation: [c] : paps + triodthy --> h + pap + triodthysuf R_ESTSULT subsystem: Steroid Metabolism R_ESTSULT equation: [c] : estrone + paps --> estrones + h + pap R_TYMSULT subsystem: Tyrosine metabolism R_TYMSULT equation: [c] : paps + tym --> h + pap + tymsf
product: 211356
reactant: 211258
is: http://identifiers.org/ec-code/2.8.2.1
is: http://identifiers.org/ec-code/2.8.2.4
is: ENSMUSG00000023122.5

211282
type: SpeciesReference
stoichiometry: 1.0
species: 187247

211234
type: SpeciesReference
stoichiometry: 1.0
species: 172246

211380
type: SpeciesReference
stoichiometry: 5.0
species: 175722

211331
type: SpeciesReference
stoichiometry: 1.0
species: 171487

171487
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Dopamine 3-O-sulfate_C8H11NO5S

211246
type: SpeciesReference
stoichiometry: 5.0
species: 183131

211306
type: SpeciesReference
stoichiometry: 1.0
species: 172306

211344
type: SpeciesReference
stoichiometry: 1.0
species: 162749

162749
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-Nitrophenyl sulfate_C6H4NO6S

211294
type: SpeciesReference
stoichiometry: 1.0
species: 171451

211270
type: SpeciesReference
stoichiometry: 1.0
species: 162737

162737
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-Nitrophenol_C6H5NO3

211368
type: SpeciesReference
stoichiometry: 1.0
species: 187271

187271
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Triiodothyronine sulfate_C15H11I3NO7S

211318
type: SpeciesReference
stoichiometry: 5.0
species: 183107

211356
type: SpeciesReference
stoichiometry: 1.0
species: 187512

187512
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Tyramine O-sulfate_C8H11NO4S

211258
type: SpeciesReference
stoichiometry: 1.0
species: 187500

163173
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _5-Hydroxyindoleacetate_C10H8NO3

951665
type: Reaction
reactant: 247928
fast: false
is: ENSMUSG00000031904.4
product: 247953
notes: R_ARGLYSex subsystem: Transport, Extracellular R_ARGLYSex equation: arg-L[e] + lys-L[c] --> arg-L[c] + lys-L[e]
product: 247940
reversible: false
name: Arginine/Lysine exchanger (Arg in)
reactant: 247916

247928
type: SpeciesReference
stoichiometry: 1.0
species: 166736

166736
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Arginine_C6H15N4O2

247953
type: SpeciesReference
stoichiometry: 1.0
species: 166724

247940
type: SpeciesReference
stoichiometry: 1.0
species: 179859

179859
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Lysine_C6H15N2O2

247916
type: SpeciesReference
stoichiometry: 1.0
species: 179847

179847
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Lysine_C6H15N2O2

177991
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 40_C40H68N2O31

185703
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Sulfate_O4S

183059
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: phosphatidylinositol (homo sapiens)_C9H16O9PFULLRCO2FULLR2CO2

947998
type: Reaction
reactant: 213604
product: 213652
is: http://identifiers.org/ec-code/2.6.1.22
reversible: true
product: 213665
is: ENSMUSG00000057880.5
reactant: 213580
reactant: 213616
product: 213677
reactant: 213592
fast: false
product: 213690
reactant: 213628
is: http://identifiers.org/ec-code/2.6.1.19
notes: R_ABTArm subsystem: Glutamate metabolism R_ABTArm equation: [m] : 4abut + akg <==> glu-L + sucsal R_3AIBTm subsystem: Valine, Leucine, and Isoleucine Metabolism R_3AIBTm equation: [m] : 2mop + glu-L <==> 3aib + akg R_APAT2rm subsystem: beta-Alanine metabolism R_APAT2rm equation: [m] : akg + ala-B <==> glu-L + msa
product: 213640

213604
type: SpeciesReference
stoichiometry: 2.0
species: 165895

165895
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _2-Oxoglutarate_C5H4O5

213652
type: SpeciesReference
stoichiometry: 1.0
species: 181186

181186
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Malonate semialdehyde_C3H3O3

213665
type: SpeciesReference
stoichiometry: 2.0
species: 174478

213580
type: SpeciesReference
stoichiometry: 1.0
species: 161453

161453
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _2-Methyl-3-oxopropanoate_C4H5O3

213616
type: SpeciesReference
stoichiometry: 1.0
species: 165955

165955
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: beta-Alanine_C3H7NO2

213677
type: SpeciesReference
stoichiometry: 1.0
species: 165895

213592
type: SpeciesReference
stoichiometry: 1.0
species: 174478

213690
type: SpeciesReference
stoichiometry: 1.0
species: 186162

213628
type: SpeciesReference
stoichiometry: 1.0
species: 162484

213640
type: SpeciesReference
stoichiometry: 1.0
species: 161733

161733
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-3-Amino-isobutanoate_C4H9NO2

956029
type: Reaction
reversible: false
product: 292762
fast: false
reactant: 292713
notes: R_CPPPGO subsystem: Heme Biosynthesis R_CPPPGO equation: [c] : cpppg3 + (2) h + o2 --> (2) co2 + (2) h2o + pppg9
is: ENSMUSG00000022742.4
product: 292750
product: 292737
reactant: 292725
name: coproporphyrinogen oxidase (O2 required)
is: http://identifiers.org/ec-code/1.3.3.3
reactant: 292701

292762
type: SpeciesReference
stoichiometry: 2.0
species: 175614

292713
type: SpeciesReference
stoichiometry: 1.0
species: 182154

292750
type: SpeciesReference
stoichiometry: 2.0
species: 168436

292737
type: SpeciesReference
stoichiometry: 1.0
species: 184038

184038
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Protoporphyrinogen IX_C34H38N4O4

292725
type: SpeciesReference
stoichiometry: 2.0
species: 175722

292701
type: SpeciesReference
stoichiometry: 1.0
species: 168690

168690
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Coproporphyrinogen III_C36H40N4O8

169890
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2

178039
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 6_C210H336N15O184S11

951341
type: Reaction
product: 245250
modifier: 245310
is: http://identifiers.org/ec-code/1.1.1.105
reactant: 245190
product: 245214
modifier: 245323
is: http://identifiers.org/ec-code/3.1.3.5
modifier: 245347
reactant: 245202
modifier: 245298
modifier: 245262
product: 245238
notes: R_RDH2a subsystem: Vitamin A Metabolism R_RDH2a equation: [c] : nadp + retinol-9-cis <==> h + nadph + retinal-cis-9 R_RDH3a subsystem: Vitamin A Metabolism R_RDH3a equation: [c] : nadp + retinol-cis-11 <==> h + nadph + retinal-11-cis R_RDH1a subsystem: Vitamin A Metabolism R_RDH1a equation: [c] : nadp + retinol <==> h + nadph + retinal R_NTD11 subsystem: Purine Catabolism R_NTD11 equation: [c] : h2o + imp --> ins + pi R_NTD3 subsystem: Pyrimidine Catabolism R_NTD3 equation: [c] : dcmp + h2o --> dcyt + pi R_NTD7 subsystem: Nucleotides R_NTD7 equation: [c] : amp + h2o --> adn + pi
product: 245226
modifier: 245286
reversible: false
reactant: 245166
modifier: 245359
modifier: 245274
fast: false
reactant: 245178
modifier: 245335
is: ENSMUSG00000020622.7

245250
type: SpeciesReference
stoichiometry: 1.0
species: 170218

245190
type: SpeciesReference
stoichiometry: 1.0
species: 166219

245214
type: SpeciesReference
stoichiometry: 3.0
species: 183652

184975
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: cis-11-retinal_C20H28O

245202
type: SpeciesReference
stoichiometry: 1.0
species: 170073

185035
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: cis-11-retinol_C20H30O

185023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _9-cis-retinol_C20H30O

245238
type: SpeciesReference
stoichiometry: 1.0
species: 177373

245226
type: SpeciesReference
stoichiometry: 1.0
species: 165321

184999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: cis-9-retinal_C20H28O

245166
type: SpeciesReference
stoichiometry: 1.0
species: 177301

177301
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: IMP_C10H11N4O8P

185060
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Retinol_C20H30O

245178
type: SpeciesReference
stoichiometry: 3.0
species: 175614

161343
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _2-Decaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone_C58H88O4

954898
type: Reaction
reactant: 280059
name: _5-Oxoproline amidohydrolase (ATP-hydrolysing) (ir)
reactant: 280071
notes: R_OPAHir subsystem: Glutathione Metabolism R_OPAHir equation: [c] : 5oxpro + atp + (2) h2o --> adp + glu-L + h + pi
product: 280119
reversible: false
is: http://identifiers.org/ec-code/3.5.2.9
fast: false
is: ENSMUSG00000022562.6
product: 280083
reactant: 280047
product: 280107
product: 280095

280059
type: SpeciesReference
stoichiometry: 1.0
species: 163305

280071
type: SpeciesReference
stoichiometry: 2.0
species: 175614

280119
type: SpeciesReference
stoichiometry: 1.0
species: 175722

280083
type: SpeciesReference
stoichiometry: 1.0
species: 183652

280047
type: SpeciesReference
stoichiometry: 1.0
species: 166904

280107
type: SpeciesReference
stoichiometry: 1.0
species: 165387

280095
type: SpeciesReference
stoichiometry: 1.0
species: 174442

954381
type: Reaction
reactant: 276179
product: 276227
notes: R_SPTix subsystem: Glycine, Serine, and Threonine Metabolism R_SPTix equation: [x] : pyr + ser-L --> ala-L + hpyr R_AGTix subsystem: Alanine and Aspartate Metabolism R_AGTix equation: [x] : ala-L + glx --> gly + pyr
product: 276252
reactant: 276191
product: 276215
fast: false
product: 276239
is: http://identifiers.org/ec-code/2.6.1.44
reactant: 276167
is: ENSMUSG00000026272.5
reactant: 276203
reversible: false

276179
type: SpeciesReference
stoichiometry: 1.0
species: 174613

174613
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Glyoxylate_C2H1O3

276227
type: SpeciesReference
stoichiometry: 1.0
species: 166063

276252
type: SpeciesReference
stoichiometry: 1.0
species: 184855

184855
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Pyruvate_C3H3O3

276191
type: SpeciesReference
stoichiometry: 1.0
species: 185568

185568
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: L-Serine_C3H7NO3

276215
type: SpeciesReference
stoichiometry: 1.0
species: 176445

176445
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Hydroxypyruvate_C3H3O4

276239
type: SpeciesReference
stoichiometry: 1.0
species: 174673

276167
type: SpeciesReference
stoichiometry: 1.0
species: 166063

276203
type: SpeciesReference
stoichiometry: 1.0
species: 184855

ORG:
  orgname: University of Missouri - Columbia
n:
  given: Conant
  family: Conant

951617
type: Reaction
product: 247660
product: 247699
product: 247686
notes: R_CERT2rt subsystem: Transport, Endoplasmic Reticular R_CERT2rt equation: gluside_hs[c] <==> gluside_hs[r] R_CERT1gt subsystem: Transport, Golgi Apparatus R_CERT1gt equation: crm_hs[c] <==> crm_hs[g] R_CERT2gt subsystem: Transport, Golgi Apparatus R_CERT2gt equation: gluside_hs[c] <==> gluside_hs[g] R_CERT1rt subsystem: Transport, Endoplasmic Reticular R_CERT1rt equation: crm_hs[c] <==> crm_hs[r]
fast: false
reactant: 247647
reactant: 247634
reversible: true
product: 247673
is: ENSMUSG00000021669.6

247660
type: SpeciesReference
stoichiometry: 1.0
species: 168775

168775
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: ceramide (homo sapiens)_C18H36NO2FULLRCO

247699
type: SpeciesReference
stoichiometry: 1.0
species: 174564

174564
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO

247686
type: SpeciesReference
stoichiometry: 1.0
species: 168751

247647
type: SpeciesReference
stoichiometry: 2.0
species: 168738

247634
type: SpeciesReference
stoichiometry: 2.0
species: 174528

247673
type: SpeciesReference
stoichiometry: 1.0
species: 174540

166051
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Alanine_C3H7NO2

173233
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: VI2Fuc-nLc6_C64H112N3O36FULLRCO

170676
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526

164775
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (Gal)2 (GalNAc)1 (Glc)1 (GlcNAc)1 (LFuc)1 (Cer)1_C58H102N3O31FULLRCO

176012
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Hexadecenoyl carnitine_C23H43NO4

186876
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Thiamin monophosphate_C12H16N4O4PS

185483
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Selenide_HSe

954141
type: Reaction
notes: R_ILETA subsystem: Valine, Leucine, and Isoleucine Metabolism R_ILETA equation: [c] : akg + ile-L <==> 3mop + glu-L R_VALTA subsystem: Valine, Leucine, and Isoleucine Metabolism R_VALTA equation: [c] : akg + val-L <==> 3mob + glu-L R_LEUTA subsystem: Valine, Leucine, and Isoleucine Metabolism R_LEUTA equation: [c] : akg + leu-L <==> 4mop + glu-L
is: ENSMUSG00000030268.8
reactant: 274139
product: 274175
fast: false
reactant: 274127
reactant: 274151
is: http://identifiers.org/ec-code/2.6.1.6
is: http://identifiers.org/ec-code/2.6.1.42
reversible: true
product: 274163
product: 274199
product: 274187
reactant: 274115

274139
type: SpeciesReference
stoichiometry: 1.0
species: 177217

177217
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Isoleucine_C6H13NO2

274175
type: SpeciesReference
stoichiometry: 1.0
species: 162095

162095
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: (S)-3-Methyl-2-oxopentanoate_C6H9O3

274127
type: SpeciesReference
stoichiometry: 1.0
species: 188200

188200
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Valine_C5H11NO2

274151
type: SpeciesReference
stoichiometry: 1.0
species: 179231

274163
type: SpeciesReference
stoichiometry: 1.0
species: 162071

162071
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Methyl-2-oxobutanoate_C5H7O3

274199
type: SpeciesReference
stoichiometry: 1.0
species: 162665

162665
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-Methyl-2-oxopentanoate_C6H9O3

274187
type: SpeciesReference
stoichiometry: 3.0
species: 174442

274115
type: SpeciesReference
stoichiometry: 3.0
species: 165871

946266
type: Reaction
reactant: 198384
reversible: false
product: 198481
is: http://identifiers.org/ec-code/1.5.1.6
product: 198493
reactant: 198432
product: 198456
fast: false
product: 198444
is: ENSMUSG00000042626.6
reactant: 198396
notes: R_FTHFDH subsystem: Folate Metabolism R_FTHFDH equation: [c] : 10fthf + h2o + nadp --> co2 + h + nadph + thf R_FDH subsystem: Fatty Acid Metabolism R_FDH equation: [c] : for + nad --> co2 + nadh
product: 198468
reactant: 198420
is: http://identifiers.org/ec-code/1.2.1.2
reactant: 198408

198384
type: SpeciesReference
stoichiometry: 1.0
species: 172788

198481
type: SpeciesReference
stoichiometry: 1.0
species: 181510

198493
type: SpeciesReference
stoichiometry: 1.0
species: 181631

198432
type: SpeciesReference
stoichiometry: 1.0
species: 160758

198456
type: SpeciesReference
stoichiometry: 2.0
species: 168436

198444
type: SpeciesReference
stoichiometry: 1.0
species: 186792

198396
type: SpeciesReference
stoichiometry: 1.0
species: 181558

198468
type: SpeciesReference
stoichiometry: 1.0
species: 175722

198420
type: SpeciesReference
stoichiometry: 1.0
species: 175614

198408
type: SpeciesReference
stoichiometry: 1.0
species: 181437

161770
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3-Decaprenyl-4-hydroxy-5-methoxybenzoate_C58H87O4

948166
type: Reaction
reactant: 215603
product: 215615
is: ENSMUSG00000023473.6
product: 215651
reactant: 215554
reactant: 215591
reactant: 215566
is: ENSMUSG00000023259.8
product: 215627
product: 215687
notes: R_CLOXAtex2 subsystem: Transport, Extracellular R_CLOXAtex2 equation: (2) cl[e] + oxa[c] --> (2) cl[c] + oxa[e] R_SO4CLtex2 subsystem: Transport, Extracellular R_SO4CLtex2 equation: cl[c] + (2) so4[e] --> cl[e] + (2) so4[c] R_SO4OXAtex2 subsystem: Transport, Extracellular R_SO4OXAtex2 equation: oxa[c] + (2) so4[e] --> oxa[e] + (2) so4[c] R_CLFORtex2 subsystem: Transport, Extracellular R_CLFORtex2 equation: (2) cl[e] + for[c] --> (2) cl[c] + for[e] R_CLOHtex2 subsystem: Transport, Extracellular R_CLOHtex2 equation: (2) cl[e] + oh1[c] --> (2) cl[c] + oh1[e] R_CLHCO3tex2 subsystem: Transport, Extracellular R_CLHCO3tex2 equation: (2) cl[e] + hco3[c] --> (2) cl[c] + hco3[e]
product: 215663
reversible: false
reactant: 215530
fast: false
product: 215639
product: 215675
reactant: 215542
is: ENSMUSG00000040441.6
reactant: 215579

215603
type: SpeciesReference
stoichiometry: 8.0
species: 168208

215615
type: SpeciesReference
stoichiometry: 1.0
species: 172800

215651
type: SpeciesReference
stoichiometry: 1.0
species: 182611

182611
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: hydroxide ion_HO

215554
type: SpeciesReference
stoichiometry: 1.0
species: 172788

215591
type: SpeciesReference
stoichiometry: 1.0
species: 182599

182599
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: hydroxide ion_HO

215566
type: SpeciesReference
stoichiometry: 1.0
species: 168196

168196
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Chloride_Cl

215627
type: SpeciesReference
stoichiometry: 2.0
species: 182731

182731
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Oxalate_C2O4

215687
type: SpeciesReference
stoichiometry: 1.0
species: 168208

215663
type: SpeciesReference
stoichiometry: 4.0
species: 185655

185655
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Sulfate_O4S

215530
type: SpeciesReference
stoichiometry: 2.0
species: 182719

182719
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Oxalate_C2O4

215639
type: SpeciesReference
stoichiometry: 8.0
species: 168196

215675
type: SpeciesReference
stoichiometry: 1.0
species: 175890

215542
type: SpeciesReference
stoichiometry: 1.0
species: 175878

215579
type: SpeciesReference
stoichiometry: 4.0
species: 185667

185667
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Sulfate_O4S

949705
type: Reaction
reactant: 228988
product: 229025
reactant: 228976
product: 229012
product: 229049
reversible: false
notes: R_25VITD3Hm subsystem: Vitamin D R_25VITD3Hm equation: [m] : 25hvitd3 + h + nadph + o2 --> 1a25dhvitd3 + h2o + nadp R_25VITD2Hm subsystem: Vitamin D R_25VITD2Hm equation: [m] : 25hvitd2 + h + nadph + o2 --> 1a25dhvitd2 + h2o + nadp
reactant: 229000
product: 229037
reactant: 228964
fast: false
reactant: 228952
is: ENSMUSG00000006724.4

228988
type: SpeciesReference
stoichiometry: 2.0
species: 182178

229025
type: SpeciesReference
stoichiometry: 1.0
species: 161064

161064
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _1-alpha,25-Dihydroxyvitamin D3_C27H44O3

228976
type: SpeciesReference
stoichiometry: 2.0
species: 181643

229012
type: SpeciesReference
stoichiometry: 2.0
species: 175662

229049
type: SpeciesReference
stoichiometry: 2.0
species: 181583

229000
type: SpeciesReference
stoichiometry: 2.0
species: 175770

229037
type: SpeciesReference
stoichiometry: 1.0
species: 161052

161052
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _1-alpha,25-Dihydroxyvitamin D2_C28H44O3

228964
type: SpeciesReference
stoichiometry: 1.0
species: 161234

161234
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _25-Hydroxyvitamin D3_C27H44O2

228952
type: SpeciesReference
stoichiometry: 1.0
species: 161222

161222
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _25-Hydroxyvitamin D2_C28H44O2

178521
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 7_C115H187N8O85SX

165713
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Etiocholan-3alpha-ol-17-one 3-glucuronide_C25H38O8

955067
type: Reaction
product: 282369
reactant: 282260
product: 282333
product: 282357
reactant: 282309
reactant: 282128
fast: false
product: 282454
product: 282430
product: 282478
product: 282514
reactant: 282273
product: 282393
reactant: 282285
product: 282321
reactant: 282200
reactant: 282297
reactant: 282212
product: 282345
product: 282490
reactant: 282224
reactant: 282140
reactant: 282152
reactant: 282236
reactant: 282164
reactant: 282248
notes: R_L_DASH_LACtm subsystem: Transport, Mitochondrial R_L_DASH_LACtm equation: h[c] + lac-L[c] <==> h[m] + lac-L[m] R_D_DASH_LACt2 subsystem: Transport, Extracellular R_D_DASH_LACt2 equation: h[e] + lac-D[e] <==> h[c] + lac-D[c] R_PYRt2m subsystem: Transport, Mitochondrial R_PYRt2m equation: h[c] + pyr[c] <==> h[m] + pyr[m] R_ACACt2m subsystem: Transport, Mitochondrial R_ACACt2m equation: acac[c] + h[c] <==> acac[m] + h[m] R_L_DASH_LACt2r subsystem: Transport, Extracellular R_L_DASH_LACt2r equation: h[e] + lac-L[e] <==> h[c] + lac-L[c] R_ACETONEt2m subsystem: Transport, Mitochondrial R_ACETONEt2m equation: acetone[c] + h[c] <==> acetone[m] + h[m] R_ACACt2 subsystem: Transport, Extracellular R_ACACt2 equation: acac[e] + h[e] <==> acac[c] + h[c] R_PYRt2r subsystem: Transport, Extracellular R_PYRt2r equation: h[e] + pyr[e] <==> h[c] + pyr[c] R_ACETONEt2 subsystem: Transport, Extracellular R_ACETONEt2 equation: acetone[e] + h[e] <==> acetone[c] + h[c] R_BUTt2m subsystem: Transport, Mitochondrial R_BUTt2m equation: but[c] + h[c] <==> but[m] + h[m] R_PYRt2p subsystem: D-alanine metabolism R_PYRt2p equation: h[c] + pyr[c] <==> h[x] + pyr[x] R_2HBt2 subsystem: Transport, Extracellular R_2HBt2 equation: _2hb[e] + h[e] <==> 2hb[c] + h[c] R_BTNt2m subsystem: Transport, Mitochondrial R_BTNt2m equation: btn[c] + h[c] <==> btn[m] + h[m] R_BUTt2r subsystem: Transport, Extracellular R_BUTt2r equation: but[e] + h[e] <==> but[c] + h[c] R_BTNt2 subsystem: Transport, Extracellular R_BTNt2 equation: btn[e] + h[e] <==> btn[c] + h[c] R_D_DASH_LACtm subsystem: Transport, Mitochondrial R_D_DASH_LACtm equation: h[c] + lac-D[c] <==> h[m] + lac-D[m]
reactant: 282176
reactant: 282188
product: 282502
product: 282381
product: 282442
product: 282405
product: 282538
reactant: 282115
product: 282526
product: 282418
product: 282466
is: ENSMUSG00000032902.1
reversible: true

282369
type: SpeciesReference
stoichiometry: 1.0
species: 167351

167351
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Butyrate (n-C4:0)_C4H7O2

282260
type: SpeciesReference
stoichiometry: 1.0
species: 164486

282333
type: SpeciesReference
stoichiometry: 1.0
species: 164510

282357
type: SpeciesReference
stoichiometry: 1.0
species: 184819

282309
type: SpeciesReference
stoichiometry: 8.0
species: 175722

282128
type: SpeciesReference
stoichiometry: 8.0
species: 175734

282454
type: SpeciesReference
stoichiometry: 1.0
species: 164691

282430
type: SpeciesReference
stoichiometry: 1.0
species: 175806

282478
type: SpeciesReference
stoichiometry: 1.0
species: 184843

184843
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Pyruvate_C3H3O3

282514
type: SpeciesReference
stoichiometry: 8.0
species: 175722

282273
type: SpeciesReference
stoichiometry: 1.0
species: 184831

282393
type: SpeciesReference
stoichiometry: 1.0
species: 167278

282285
type: SpeciesReference
stoichiometry: 1.0
species: 179050

282321
type: SpeciesReference
stoichiometry: 1.0
species: 161381

282200
type: SpeciesReference
stoichiometry: 1.0
species: 167278

282297
type: SpeciesReference
stoichiometry: 1.0
species: 167339

167339
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Butyrate (n-C4:0)_C4H7O2

282212
type: SpeciesReference
stoichiometry: 1.0
species: 164498

282345
type: SpeciesReference
stoichiometry: 1.0
species: 164667

282490
type: SpeciesReference
stoichiometry: 1.0
species: 179110

179110
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Lactate_C3H5O3

282224
type: SpeciesReference
stoichiometry: 1.0
species: 161393

282140
type: SpeciesReference
stoichiometry: 1.0
species: 179098

282152
type: SpeciesReference
stoichiometry: 1.0
species: 179062

282236
type: SpeciesReference
stoichiometry: 1.0
species: 167327

282164
type: SpeciesReference
stoichiometry: 1.0
species: 167290

167290
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Biotin_C10H15N2O3S

282248
type: SpeciesReference
stoichiometry: 1.0
species: 179086

282176
type: SpeciesReference
stoichiometry: 1.0
species: 164667

282188
type: SpeciesReference
stoichiometry: 2.0
species: 184819

282502
type: SpeciesReference
stoichiometry: 1.0
species: 179050

282381
type: SpeciesReference
stoichiometry: 1.0
species: 167303

282442
type: SpeciesReference
stoichiometry: 1.0
species: 179086

282405
type: SpeciesReference
stoichiometry: 1.0
species: 179074

179074
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: D-Lactate_C3H5O3

282538
type: SpeciesReference
stoichiometry: 1.0
species: 184855

282115
type: SpeciesReference
stoichiometry: 1.0
species: 164679

282526
type: SpeciesReference
stoichiometry: 7.0
species: 175770

282418
type: SpeciesReference
stoichiometry: 1.0
species: 167327

282466
type: SpeciesReference
stoichiometry: 1.0
species: 164486

183784
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Palmitoylcarnitine_C23H45NO4

161197
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _2,4 dihydroxy nitrophenol_C6H5NO4

950090
type: Reaction
product: 234553
product: 234614
reactant: 234432
reactant: 234420
product: 234505
product: 234686
product: 234698
reversible: false
product: 234638
reactant: 234384
product: 234589
product: 234601
reactant: 234372
reactant: 234444
product: 234662
product: 234565
reactant: 234408
reactant: 234300
product: 234517
reactant: 234360
reactant: 234348
reactant: 234336
reactant: 234396
product: 234541
fast: false
reactant: 234493
reactant: 234481
reactant: 234324
product: 234674
reactant: 234469
reactant: 234312
product: 234626
is: ENSMUSG00000020744.4
product: 234529
product: 234577
reactant: 234457
notes: R_DNDPt49m subsystem: Transport, Mitochondrial R_DNDPt49m equation: dadp[m] + dttp[c] --> dadp[c] + dttp[m] R_DNDPt22m subsystem: Transport, Mitochondrial R_DNDPt22m equation: dtdp[c] + dudp[m] --> dtdp[m] + dudp[c] R_DNDPt17m subsystem: Transport, Mitochondrial R_DNDPt17m equation: dcdp[m] + dudp[c] --> dcdp[c] + dudp[m] R_DNDPt11m subsystem: Transport, Mitochondrial R_DNDPt11m equation: dadp[c] + dgdp[m] --> dadp[m] + dgdp[c] R_DNDPt52m subsystem: Transport, Mitochondrial R_DNDPt52m equation: dctp[c] + dudp[m] --> dctp[m] + dudp[c] R_DNDPt2m subsystem: Transport, Mitochondrial R_DNDPt2m equation: atp[m] + datp[c] --> atp[c] + datp[m] R_DNDPt63m subsystem: Transport, Mitochondrial R_DNDPt63m equation: dcdp[m] + dgtp[c] --> dcdp[c] + dgtp[m] R_DNDPt47m subsystem: Transport, Mitochondrial R_DNDPt47m equation: dtdp[m] + dttp[c] --> dtdp[c] + dttp[m] R_DNDPt13m subsystem: Transport, Mitochondrial R_DNDPt13m equation: atp[m] + dadp[c] --> atp[c] + dadp[m] R_DNDPt32m subsystem: Transport, Mitochondrial R_DNDPt32m equation: atp[m] + dgdp[c] --> atp[c] + dgdp[m] R_DNDPt12m subsystem: Transport, Mitochondrial R_DNDPt12m equation: adp[m] + dadp[c] --> adp[c] + dadp[m] R_DNDPt46m subsystem: Transport, Mitochondrial R_DNDPt46m equation: dttp[c] + dudp[m] --> dttp[m] + dudp[c] R_DNDPt28m subsystem: Transport, Mitochondrial R_DNDPt28m equation: dcdp[c] + dgdp[m] --> dcdp[m] + dgdp[c] R_DNDPt60m subsystem: Transport, Mitochondrial R_DNDPt60m equation: dgtp[c] + dudp[m] --> dgtp[m] + dudp[c] R_DNDPt24m subsystem: Transport, Mitochondrial R_DNDPt24m equation: dadp[m] + dtdp[c] --> dadp[c] + dtdp[m] R_DNDPt30m subsystem: Transport, Mitochondrial R_DNDPt30m equation: adp[m] + dcdp[c] --> adp[c] + dcdp[m] R_DNDPt54m subsystem: Transport, Mitochondrial R_DNDPt54m equation: dadp[m] + dctp[c] --> dadp[c] + dctp[m] R_DNDPt29m subsystem: Transport, Mitochondrial R_DNDPt29m equation: dadp[m] + dcdp[c] --> dadp[c] + dcdp[m] R_DNDPt8m subsystem: Transport, Mitochondrial R_DNDPt8m equation: da…
product: 234650

234553
type: SpeciesReference
stoichiometry: 7.0
species: 169963

234614
type: SpeciesReference
stoichiometry: 5.0
species: 170423

234432
type: SpeciesReference
stoichiometry: 10.0
species: 166928

234420
type: SpeciesReference
stoichiometry: 7.0
species: 170532

234505
type: SpeciesReference
stoichiometry: 6.0
species: 171728

234686
type: SpeciesReference
stoichiometry: 6.0
species: 169853

234698
type: SpeciesReference
stoichiometry: 9.0
species: 170411

234638
type: SpeciesReference
stoichiometry: 7.0
species: 170544

234384
type: SpeciesReference
stoichiometry: 7.0
species: 169951

234589
type: SpeciesReference
stoichiometry: 9.0
species: 171716

234601
type: SpeciesReference
stoichiometry: 8.0
species: 171571

234372
type: SpeciesReference
stoichiometry: 9.0
species: 165411

234444
type: SpeciesReference
stoichiometry: 9.0
species: 170037

234662
type: SpeciesReference
stoichiometry: 6.0
species: 170037

234565
type: SpeciesReference
stoichiometry: 10.0
species: 166904

234408
type: SpeciesReference
stoichiometry: 9.0
species: 170423

234300
type: SpeciesReference
stoichiometry: 9.0
species: 171728

234517
type: SpeciesReference
stoichiometry: 6.0
species: 170193

234360
type: SpeciesReference
stoichiometry: 7.0
species: 171680

234348
type: SpeciesReference
stoichiometry: 6.0
species: 171716

234336
type: SpeciesReference
stoichiometry: 6.0
species: 169841

234396
type: SpeciesReference
stoichiometry: 6.0
species: 171571

234541
type: SpeciesReference
stoichiometry: 7.0
species: 171692

234493
type: SpeciesReference
stoichiometry: 6.0
species: 170181

234481
type: SpeciesReference
stoichiometry: 5.0
species: 170411

234324
type: SpeciesReference
stoichiometry: 7.0
species: 171824

234674
type: SpeciesReference
stoichiometry: 9.0
species: 170024

234469
type: SpeciesReference
stoichiometry: 9.0
species: 169853

234312
type: SpeciesReference
stoichiometry: 8.0
species: 171583

234626
type: SpeciesReference
stoichiometry: 9.0
species: 165387

234529
type: SpeciesReference
stoichiometry: 6.0
species: 171583

234577
type: SpeciesReference
stoichiometry: 9.0
species: 169841

234457
type: SpeciesReference
stoichiometry: 6.0
species: 170024

234650
type: SpeciesReference
stoichiometry: 7.0
species: 171836

954525
type: Reaction
notes: R_RAI3 subsystem: Vitamin A Metabolism R_RAI3 equation: [c] : retn <==> 13-cis-retn
is: ENSMUSG00000068762.3
fast: false
is: ENSMUSG00000040562.5
product: 277143
reversible: true
reactant: 277131
is: ENSMUSG00000058135.4
name: _13-cis-retinoic acid isomerase
is: ENSMUSG00000004035.4
is: ENSMUSG00000027890.8
is: ENSMUSG00000004038.7
is: ENSMUSG00000063042.3

277143
type: SpeciesReference
stoichiometry: 1.0
species: 160919

160919
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _13-cis-retinoate_C20H27O2

277131
type: SpeciesReference
stoichiometry: 1.0
species: 185072

185072
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Retinoate_C20H27O2

163715
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: protein-linked asparagine residue (N-glycosylation site)_XH

164270
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: S-Formylglutathione_C11H16N3O7S

185109
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Ribose_C5H10O5

181996
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Naphthalene_C10H8

164547
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Acetaldehyde_C2H4O

179691
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: alpha-linolenyl carnitine_C25H43NO4

173125
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (Gal)3 (Glc)1 (GlcNAc)2 (LFuc)3 (Cer)1_C76H132N3O44FULLRCO

168557
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Coenzyme A_C21H32N7O16P3S

180331
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Malonyl-[acyl-carrier protein]_C14H22N2O10PRS

174058
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GD1c (homo sapiens)_C66H111N4O38FULLRCO

179920
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (dimannosyl),(phosphoethanolaminyl)-mannosyl-glucosylaminyl-acylphosphatidylinositol (H6)_C51H94N2O32P2FULLRCO2FULLR2CO2

168983
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 2_C37H55NO38S2

173679
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Gal-GlcNAc-Gal globoside (homo sapiens)_C64H112N3O37FULLRCO

163027
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: pentaglutamyl folate (DHF)_C39H43N11O18

165605
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Adrenyl carnitine_C29H49NO4

946434
type: Reaction
reactant: 199656
fast: false
is: http://identifiers.org/ec-code/2.5.1.10
product: 199728
is: http://identifiers.org/ec-code/3.1.3.66
reactant: 199668
reactant: 199632
reactant: 199620
notes: R_MI34PP subsystem: Inositol Phosphate Metabolism R_MI34PP equation: [c] : h2o + mi34p --> mi3p-D + pi R_DMATTx subsystem: Cholesterol Metabolism R_DMATTx equation: [x] : dmpp + ipdp --> grdp + ppi R_GRTTx subsystem: Cholesterol Metabolism R_GRTTx equation: [x] : grdp + ipdp --> frdp + ppi
product: 199692
product: 199680
product: 199704
reactant: 199644
reversible: false
is: ENSMUSG00000059743.6
is: http://identifiers.org/ec-code/2.5.1.1
product: 199716

199656
type: SpeciesReference
stoichiometry: 1.0
species: 175614

199728
type: SpeciesReference
stoichiometry: 1.0
species: 172920

172920
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Farnesyl diphosphate_C15H25O7P2

199668
type: SpeciesReference
stoichiometry: 2.0
species: 177447

177447
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Isopentenyl diphosphate_C5H9O7P2

199632
type: SpeciesReference
stoichiometry: 1.0
species: 180994

199620
type: SpeciesReference
stoichiometry: 1.0
species: 175197

175197
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Geranyl diphosphate_C10H17O7P2

199692
type: SpeciesReference
stoichiometry: 2.0
species: 183966

183966
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Diphosphate_HO7P2

199680
type: SpeciesReference
stoichiometry: 1.0
species: 175197

199704
type: SpeciesReference
stoichiometry: 1.0
species: 183652

199644
type: SpeciesReference
stoichiometry: 1.0
species: 171208

171208
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Dimethylallyl diphosphate_C5H9O7P2

199716
type: SpeciesReference
stoichiometry: 1.0
species: 181006

167833
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Choline_C5H14NO

948226
type: Reaction
product: 215990
is: http://identifiers.org/ec-code/3.5.4.9
is: ENSMUSG00000029376.7
reactant: 215942
product: 216002
notes: R_MTHFD2 subsystem: Folate Metabolism R_MTHFD2 equation: [c] : mlthf + nad <==> methf + nadh R_MTHFC subsystem: Folate Metabolism R_MTHFC equation: [c] : h2o + methf <==> 10fthf + h
product: 215966
reactant: 215930
reversible: true
fast: false
reactant: 215917
product: 215978
is: http://identifiers.org/ec-code/1.5.1.5
reactant: 215954

215990
type: SpeciesReference
stoichiometry: 1.0
species: 160758

215942
type: SpeciesReference
stoichiometry: 1.0
species: 180764

216002
type: SpeciesReference
stoichiometry: 1.0
species: 181510

215966
type: SpeciesReference
stoichiometry: 1.0
species: 180764

215930
type: SpeciesReference
stoichiometry: 1.0
species: 181437

215917
type: SpeciesReference
stoichiometry: 1.0
species: 181054

215978
type: SpeciesReference
stoichiometry: 1.0
species: 175722

215954
type: SpeciesReference
stoichiometry: 1.0
species: 175614

163607
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heptaglutamyl folate (DHF)_C49H55N13O24

166123
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: S-aminomethyldihydrolipoamide_C9H21N2OS2

165459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: ADPglucose_C16H23N5O15P2

176301
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526

172716
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: FMN_C17H19N4O9P

178377
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 2_C87H142N6O62X

188261
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: w-hydroxyl arachidonic acid_C20H31O3

177954
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 38_C54H91N3O41

952868
type: Reaction
reversible: false
reactant: 262434
fast: false
product: 262471
reactant: 262410
reactant: 262422
product: 262458
product: 262483
reactant: 262446
product: 262495
is: http://identifiers.org/ec-code/6.2.1.3
notes: R_FACOAL180i subsystem: Fatty acid activation R_FACOAL180i equation: [c] : atp + coa + ocdca --> amp + ppi + stcoa R_FACOAL160i subsystem: Fatty acid activation R_FACOAL160i equation: [c] : atp + coa + hdca --> amp + pmtcoa + ppi
is: ENSMUSG00000024981.3

262434
type: SpeciesReference
stoichiometry: 2.0
species: 166904

262471
type: SpeciesReference
stoichiometry: 1.0
species: 185921

262410
type: SpeciesReference
stoichiometry: 1.0
species: 175938

262422
type: SpeciesReference
stoichiometry: 2.0
species: 168509

262458
type: SpeciesReference
stoichiometry: 1.0
species: 183748

262483
type: SpeciesReference
stoichiometry: 2.0
species: 166219

262446
type: SpeciesReference
stoichiometry: 1.0
species: 182418

262495
type: SpeciesReference
stoichiometry: 2.0
species: 183917

187753
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: UDPgalactose_C15H22N2O17P2

948394
type: Reaction
reactant: 217231
product: 217303
product: 217291
fast: false
is: ENSMUSG00000035704.8
reactant: 217255
product: 217279
reactant: 217219
reversible: false
product: 217315
notes: R_DOLPGT2_Ler subsystem: N-Glycan Biosynthesis R_DOLPGT2_Ler equation: [r] : (0.1) dolglcp_L + (0.1) g1m8mpdol_L --> (0.1) dolp_L + (0.1) g2m8mpdol_L + h R_DOLPGT2_Uer subsystem: N-Glycan Biosynthesis R_DOLPGT2_Uer equation: [r] : (0.1) dolglcp_U + (0.1) g1m8mpdol_U --> (0.1) dolp_U + (0.1) g2m8mpdol_U + h
product: 217267
reactant: 217243

217231
type: SpeciesReference
stoichiometry: 1.0
species: 171343

171343
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Dolichyl beta-D-glucosyl phosphate, human uterine homolog_C1085H1780O90P10

217303
type: SpeciesReference
stoichiometry: 1.0
species: 171439

171439
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Dolichol phosphate, human uterine homolog_C1025H1670O40P10

217291
type: SpeciesReference
stoichiometry: 1.0
species: 173401

217255
type: SpeciesReference
stoichiometry: 1.0
species: 173353

173353
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: alpha-D-Glucosyl-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1840H3028N20O670P20

217279
type: SpeciesReference
stoichiometry: 1.0
species: 173413

173413
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1845H3040N20O720P20

217219
type: SpeciesReference
stoichiometry: 1.0
species: 171319

171319
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Dolichyl beta-D-glucosyl phosphate, human liver homolog_C1140H1868O90P10

217315
type: SpeciesReference
stoichiometry: 2.0
species: 175794

217267
type: SpeciesReference
stoichiometry: 1.0
species: 171415

171415
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Dolichol phosphate, human liver homolog_C1080H1758O40P10

217243
type: SpeciesReference
stoichiometry: 1.0
species: 173365

173365
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: alpha-D-Glucosyl-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1785H2940N20O670P20

184134
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Pregnenolone_C21H32O2

169780
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Cytidine_C9H13N3O5

175171
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GQ1c (homo sapiens)_C88H143N6O54FULLRCO

953685
type: Reaction
is: http://identifiers.org/ec-code/1.1.99.5
product: 268805
product: 268818
name: glycerol-3-phosphate dehydrogenase (FAD), mitochondrial
reactant: 268792
fast: false
notes: R_G3PD2m subsystem: Glycolysis/Gluconeogenesis R_G3PD2m equation: fad[m] + glyc3p[c] --> dhap[c] + fadh2[m]
is: ENSMUSG00000026827.4
reversible: false
reactant: 268779

268805
type: SpeciesReference
stoichiometry: 1.0
species: 172547

268818
type: SpeciesReference
stoichiometry: 1.0
species: 170580

170580
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Dihydroxyacetone phosphate_C3H5O6P

268792
type: SpeciesReference
stoichiometry: 1.0
species: 172499

268779
type: SpeciesReference
stoichiometry: 1.0
species: 174721

174721
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Glycerol 3-phosphate_C3H7O6P

169988
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Decanoyl-CoA (n-C10:0CoA)_C31H50N7O17P3S

177023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Hexadecanal_C16H32O

947276
type: Reaction
reactant: 208057
reactant: 208069
fast: false
reversible: false
product: 208081
is: ENSMUSG00000039037.4
notes: R_ST6GALNAC31 subsystem: Sphingolipid Metabolism R_ST6GALNAC31 equation: [g] : cmpacna + gm1b_hs --> cmp + gd1alpha_hs + h
name: Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
is: ENSMUSG00000052544.4
product: 208105
product: 208093

208057
type: SpeciesReference
stoichiometry: 1.0
species: 168388

208069
type: SpeciesReference
stoichiometry: 1.0
species: 174938

208081
type: SpeciesReference
stoichiometry: 1.0
species: 175746

208105
type: SpeciesReference
stoichiometry: 1.0
species: 168340

208093
type: SpeciesReference
stoichiometry: 1.0
species: 174020

174020
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GD1a (homo sapiens)_C66H111N4O38FULLRCO

951137
type: Reaction
reactant: 243947
reversible: false
notes: R_CORE2GTg subsystem: O-Glycan Biosynthesis R_CORE2GTg equation: [g] : T_antigen + uacgam --> core2 + h + udp
product: 243971
is: http://identifiers.org/ec-code/2.4.1.102
is: ENSMUSG00000080188.1
product: 243995
product: 243983
reactant: 243959
name: Core 2 acetylglucosaminyltransferase, Golgi apparatus
fast: false

243947
type: SpeciesReference
stoichiometry: 1.0
species: 187572

243971
type: SpeciesReference
stoichiometry: 1.0
species: 187608

243995
type: SpeciesReference
stoichiometry: 1.0
species: 168605

243983
type: SpeciesReference
stoichiometry: 1.0
species: 175746

243959
type: SpeciesReference
stoichiometry: 1.0
species: 164306

164306
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: T antigen (core 1)_C14H24NO10X

954177
type: Reaction
reactant: 274392
product: 274405
is: ENSMUSG00000024597.8
product: 274418
fast: false
product: 274442
reversible: true
product: 274430
reactant: 274380
notes: R_NKCCt subsystem: Transport, Extracellular R_NKCCt equation: (2) cl[e] + k[e] + na1[e] <==> (2) cl[c] + k[c] + na1[c] R_NKCC2t subsystem: Transport, Extracellular R_NKCC2t equation: (2) cl[e] + na1[e] + nh4[e] <==> (2) cl[c] + na1[c] + nh4[c]
reactant: 274356
is: ENSMUSG00000027202.5
reactant: 274368

274392
type: SpeciesReference
stoichiometry: 4.0
species: 168208

274405
type: SpeciesReference
stoichiometry: 1.0
species: 177531

274418
type: SpeciesReference
stoichiometry: 4.0
species: 168196

274442
type: SpeciesReference
stoichiometry: 2.0
species: 181377

274430
type: SpeciesReference
stoichiometry: 1.0
species: 181752

274380
type: SpeciesReference
stoichiometry: 2.0
species: 181389

274356
type: SpeciesReference
stoichiometry: 1.0
species: 177543

274368
type: SpeciesReference
stoichiometry: 1.0
species: 181764

953445
type: Reaction
is: ENSMUSG00000040660.5
fast: false
is: ENSMUSG00000003053.7
reactant: 266948
is: ENSMUSG00000040583.6
is: ENSMUSG00000025479.6
is: ENSMUSG00000025003.3
notes: R_ACTNMO subsystem: Pyruvate Metabolism R_ACTNMO equation: [c] : acetone + h + nadph + o2 --> acetol + h2o + nadp R_ETOHMO subsystem: Glycolysis/Gluconeogenesis R_ETOHMO equation: [c] : etoh + h + nadph + o2 --> acald + (2) h2o + nadp R_P4502E1 subsystem: CYP Metabolism R_P4502E1 equation: [c] : 4nph + h + nadph + o2 --> 24nph + h2o + nadp R_ACTLMO subsystem: Pyruvate Metabolism R_ACTLMO equation: [c] : acetol + h + nadph + o2 --> (2) h2o + mthgxl + nadp
is: ENSMUSG00000054827.5
is: ENSMUSG00000067225.1
product: 267046
is: ENSMUSG00000025197.7
product: 267082
is: ENSMUSG00000032808.2
is: ENSMUSG00000060613.3
is: ENSMUSG00000042248.2
reactant: 266973
is: ENSMUSG00000067231.3
reactant: 266961
reversible: false
is: ENSMUSG00000067229.2
product: 267070
is: ENSMUSG00000030483.7
is: ENSMUSG00000074254.2
is: ENSMUSG00000025004.5
reactant: 266997
product: 267033
is: ENSMUSG00000074882.2
reactant: 267021
is: ENSMUSG00000062624.4
product: 267058
product: 267094
reactant: 266985
reactant: 267009

266948
type: SpeciesReference
stoichiometry: 1.0
species: 164667

267046
type: SpeciesReference
stoichiometry: 1.0
species: 164534

267082
type: SpeciesReference
stoichiometry: 6.0
species: 175614

266973
type: SpeciesReference
stoichiometry: 1.0
species: 172403

266961
type: SpeciesReference
stoichiometry: 1.0
species: 162737

267070
type: SpeciesReference
stoichiometry: 4.0
species: 181558

266997
type: SpeciesReference
stoichiometry: 4.0
species: 182154

267033
type: SpeciesReference
stoichiometry: 1.0
species: 181198

267021
type: SpeciesReference
stoichiometry: 4.0
species: 181631

267058
type: SpeciesReference
stoichiometry: 1.0
species: 161197

267094
type: SpeciesReference
stoichiometry: 1.0
species: 164655

266985
type: SpeciesReference
stoichiometry: 1.0
species: 164655

267009
type: SpeciesReference
stoichiometry: 4.0
species: 175722

183289
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Pyridoxine 5'-phosphate_C8H10NO6P

171331
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Dolichyl beta-D-glucosyl phosphate, human uterine homolog_C1085H1780O90P10

946193
type: Reaction
reactant: 197916
notes: R_CTPS1 subsystem: Nucleotides R_CTPS1 equation: [c] : atp + nh4 + utp --> adp + ctp + (2) h + pi
fast: false
is: ENSMUSG00000029863.6
reactant: 197904
is: http://identifiers.org/ec-code/6.3.4.2
product: 197964
name: CTP synthase (NH3)
product: 197940
product: 197952
product: 197928
reversible: false
reactant: 197892

197916
type: SpeciesReference
stoichiometry: 1.0
species: 181752

197904
type: SpeciesReference
stoichiometry: 1.0
species: 188092

197964
type: SpeciesReference
stoichiometry: 1.0
species: 169615

197940
type: SpeciesReference
stoichiometry: 1.0
species: 183652

197952
type: SpeciesReference
stoichiometry: 2.0
species: 175722

197928
type: SpeciesReference
stoichiometry: 1.0
species: 165387

197892
type: SpeciesReference
stoichiometry: 1.0
species: 166904

164872
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: N-Acetyl-D-glucosamine_C8H15NO6

955921
type: Reaction
reversible: false
reactant: 291739
reactant: 291751
is: ENSMUSG00000055471.5
product: 291775
notes: R_ASAH1 subsystem: Sphingolipid Metabolism R_ASAH1 equation: [l] : crm_hs + h2o --> Rtotal + sphings
product: 291763
fast: false
name: N-acylsphingosine amidohydrolase
is: http://identifiers.org/ec-code/3.5.1.23

291739
type: SpeciesReference
stoichiometry: 1.0
species: 168763

291751
type: SpeciesReference
stoichiometry: 1.0
species: 175650

291775
type: SpeciesReference
stoichiometry: 1.0
species: 164150

291763
type: SpeciesReference
stoichiometry: 1.0
species: 185777

947036
type: Reaction
product: 205738
notes: R_THRt4 subsystem: Transport, Extracellular R_THRt4 equation: na1[e] + thr-L[e] --> na1[c] + thr-L[c] R_HISt4 subsystem: Transport, Extracellular R_HISt4 equation: his-L[e] + na1[e] --> his-L[c] + na1[c] R_SERt4 subsystem: Transport, Extracellular R_SERt4 equation: na1[e] + ser-L[e] --> na1[c] + ser-L[c] R_ALAt4 subsystem: Transport, Extracellular R_ALAt4 equation: ala-L[e] + na1[e] --> ala-L[c] + na1[c] R_PROt4 subsystem: Transport, Extracellular R_PROt4 equation: na1[e] + pro-L[e] --> na1[c] + pro-L[c] R_ASNt4 subsystem: Transport, Extracellular R_ASNt4 equation: asn-L[e] + na1[e] --> asn-L[c] + na1[c] R_METt4 subsystem: Transport, Extracellular R_METt4 equation: met-L[e] + na1[e] --> met-L[c] + na1[c] R_GLYt4 subsystem: Transport, Extracellular R_GLYt4 equation: gly[e] + na1[e] --> gly[c] + na1[c] R_PHEt4 subsystem: Transport, Extracellular R_PHEt4 equation: na1[e] + phe-L[e] --> na1[c] + phe-L[c] R_GLNt4 subsystem: Transport, Extracellular R_GLNt4 equation: gln-L[e] + na1[e] --> gln-L[c] + na1[c]
product: 205822
product: 205786
product: 205834
reactant: 205666
reversible: false
reactant: 205642
is: ENSMUSG00000022462.6
reactant: 205654
product: 205798
reactant: 205606
product: 205762
product: 205726
reactant: 205594
fast: false
product: 205810
reactant: 205702
reactant: 205618
product: 205750
reactant: 205678
reactant: 205630
reactant: 205690
reactant: 205714
product: 205774
product: 205846

205738
type: SpeciesReference
stoichiometry: 1.0
species: 185532

205822
type: SpeciesReference
stoichiometry: 1.0
species: 166015

205786
type: SpeciesReference
stoichiometry: 1.0
species: 166796

166796
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Asparagine_C4H8N2O3

205834
type: SpeciesReference
stoichiometry: 1.0
species: 183483

183483
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Phenylalanine_C9H11NO2

205666
type: SpeciesReference
stoichiometry: 1.0
species: 174637

205642
type: SpeciesReference
stoichiometry: 10.0
species: 181389

205654
type: SpeciesReference
stoichiometry: 1.0
species: 184338

184338
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Proline_C5H9NO2

205798
type: SpeciesReference
stoichiometry: 1.0
species: 180740

205606
type: SpeciesReference
stoichiometry: 1.0
species: 166027

205762
type: SpeciesReference
stoichiometry: 1.0
species: 176216

205726
type: SpeciesReference
stoichiometry: 1.0
species: 174625

205594
type: SpeciesReference
stoichiometry: 1.0
species: 176228

176228
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Histidine_C6H9N3O2

205810
type: SpeciesReference
stoichiometry: 1.0
species: 186936

205702
type: SpeciesReference
stoichiometry: 1.0
species: 185544

205618
type: SpeciesReference
stoichiometry: 1.0
species: 166808

166808
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Asparagine_C4H8N2O3

205750
type: SpeciesReference
stoichiometry: 1.0
species: 174382

174382
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Glutamine_C5H10N2O3

205678
type: SpeciesReference
stoichiometry: 1.0
species: 186948

186948
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Threonine_C4H9NO3

205630
type: SpeciesReference
stoichiometry: 1.0
species: 180752

205690
type: SpeciesReference
stoichiometry: 1.0
species: 174394

174394
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Glutamine_C5H10N2O3

205714
type: SpeciesReference
stoichiometry: 1.0
species: 183496

205774
type: SpeciesReference
stoichiometry: 10.0
species: 181377

205846
type: SpeciesReference
stoichiometry: 1.0
species: 184326

949909
type: Reaction
product: 230742
notes: R_PPNCL3 subsystem: CoA Biosynthesis R_PPNCL3 equation: [c] : 4ppan + atp + cys-L --> 4ppcys + amp + h + ppi
reactant: 230706
is: http://identifiers.org/ec-code/6.3.2.5
reactant: 230694
product: 230754
fast: false
product: 230718
reactant: 230682
reversible: false
name: phosphopantothenate-cysteine ligase
is: ENSMUSG00000028636.7
product: 230730

230742
type: SpeciesReference
stoichiometry: 1.0
species: 175722

230706
type: SpeciesReference
stoichiometry: 1.0
species: 162761

162761
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-4'-Phosphopantothenate_C9H15NO8P

230694
type: SpeciesReference
stoichiometry: 1.0
species: 166904

230754
type: SpeciesReference
stoichiometry: 1.0
species: 183917

230718
type: SpeciesReference
stoichiometry: 1.0
species: 162787

162787
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-((R)-4-Phosphopantothenoyl)-L-cysteine_C12H20N2O9PS

230682
type: SpeciesReference
stoichiometry: 1.0
species: 169680

230730
type: SpeciesReference
stoichiometry: 1.0
species: 166219

950894
type: Reaction
is: ENSMUSG00000017307.7
reactant: 242090
fast: false
product: 242114
notes: R_PTE2x subsystem: Fatty Acid Metabolism R_PTE2x equation: [x] : h2o + pmtcoa --> coa + h + hdca
reactant: 242102
product: 242138
name: peroxisomal acyl-CoA thioesterase
product: 242126
reversible: false

242090
type: SpeciesReference
stoichiometry: 1.0
species: 183772

242114
type: SpeciesReference
stoichiometry: 1.0
species: 168581

242102
type: SpeciesReference
stoichiometry: 1.0
species: 175698

242138
type: SpeciesReference
stoichiometry: 1.0
species: 175974

175974
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Hexadecanoate (n-C16:0)_C16H31O2

242126
type: SpeciesReference
stoichiometry: 1.0
species: 175806

949223
type: Reaction
product: 224691
reactant: 224679
notes: R_H2Otm subsystem: Transport, Mitochondrial R_H2Otm equation: h2o[c] <==> h2o[m]
is: ENSMUSG00000030762.4
fast: false
reversible: true
name: H2O transport, mitochondrial

224691
type: SpeciesReference
stoichiometry: 1.0
species: 175662

224679
type: SpeciesReference
stoichiometry: 1.0
species: 175614

178269
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 21_C177H284N12O145S6X

174262
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: D-glucurono-6,3-lactone_C6H8O6

947312
type: Reaction
is: ENSMUSG00000031432.2
product: 208361
reactant: 208349
is: ENSMUSG00000025742.4
is: ENSMUSG00000079104.1
reversible: true
reactant: 208336
product: 208385
fast: false
notes: R_PRPPS subsystem: Pentose Phosphate Pathway R_PRPPS equation: [c] : atp + r5p <==> amp + h + prpp
is: ENSMUSG00000020528.6
is: http://identifiers.org/ec-code/2.7.6.1
name: phosphoribosylpyrophosphate synthetase
product: 208373

208361
type: SpeciesReference
stoichiometry: 1.0
species: 184579

184579
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-Phospho-alpha-D-ribose 1-diphosphate_C5H8O14P3

208349
type: SpeciesReference
stoichiometry: 1.0
species: 166904

208336
type: SpeciesReference
stoichiometry: 1.0
species: 184939

208385
type: SpeciesReference
stoichiometry: 1.0
species: 175722

208373
type: SpeciesReference
stoichiometry: 1.0
species: 166219

180306
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: monoacylglycerol 2 (homo sapiens)_C3H7O2FULLR2CO2

174841
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: glycogen, structure 1 (glycogenin-11[1,4-Glc])_C66H111O56X

181959
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Methylserotonin_C11H15N2O

949391
type: Reaction
is: http://identifiers.org/ec-code/3.2.1.46
product: 226840
fast: false
reversible: false
notes: R_GALC subsystem: Sphingolipid Metabolism R_GALC equation: [l] : galside_hs + h2o --> crm_hs + gal
reactant: 226816
product: 226852
name: Galactocerebrosidase
reactant: 226828
is: ENSMUSG00000021003.7

226840
type: SpeciesReference
stoichiometry: 1.0
species: 168763

226816
type: SpeciesReference
stoichiometry: 1.0
species: 175650

226852
type: SpeciesReference
stoichiometry: 1.0
species: 173607

173607
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: D-Galactose_C6H12O6

226828
type: SpeciesReference
stoichiometry: 1.0
species: 173838

955728
type: Reaction
reactant: 290460
fast: false
is: ENSMUSG00000020456.8
reversible: false
is: ENSMUSG00000004789.7
reactant: 290484
product: 290520
product: 290508
is: http://identifiers.org/ec-code/1.2.4.2
product: 290532
reactant: 290448
reactant: 290472
product: 290496
notes: R_2OXOADOXm subsystem: Lysine Metabolism R_2OXOADOXm equation: [m] : 2oxoadp + coa + nad --> co2 + glutcoa + nadh R_AKGDm subsystem: Citric Acid Cycle R_AKGDm equation: [m] : akg + coa + nad --> co2 + nadh + succoa

290460
type: SpeciesReference
stoichiometry: 2.0
species: 168545

290484
type: SpeciesReference
stoichiometry: 2.0
species: 181461

290520
type: SpeciesReference
stoichiometry: 1.0
species: 174576

174576
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Glutaryl-CoA_C26H37N7O19P3S

290508
type: SpeciesReference
stoichiometry: 2.0
species: 168461

290532
type: SpeciesReference
stoichiometry: 2.0
species: 181522

290448
type: SpeciesReference
stoichiometry: 1.0
species: 161501

290472
type: SpeciesReference
stoichiometry: 1.0
species: 165895

290496
type: SpeciesReference
stoichiometry: 1.0
species: 186138

946663
type: Reaction
fast: false
reversible: false
reactant: 202674
product: 202711
name: N-acteylglutamate synthase, mitochondrial
product: 202699
reactant: 202686
notes: R_ACGSm subsystem: Urea cycle/amino group metabolism R_ACGSm equation: [m] : accoa + glu-L --> acglu + coa + h
is: ENSMUSG00000048217.4
product: 202723
is: http://identifiers.org/ec-code/2.3.1.1

202674
type: SpeciesReference
stoichiometry: 1.0
species: 164607

202711
type: SpeciesReference
stoichiometry: 1.0
species: 168545

202699
type: SpeciesReference
stoichiometry: 1.0
species: 164968

164968
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: N-Acetyl-L-glutamate_C7H9NO5

202686
type: SpeciesReference
stoichiometry: 1.0
species: 174478

202723
type: SpeciesReference
stoichiometry: 1.0
species: 175770

174008
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GD1a (homo sapiens)_C66H111N4O38FULLRCO

184867
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Ubiquinone-10_C59H90O4

948971
type: Reaction
fast: false
reversible: false
product: 222608
notes: R_XYLK subsystem: Pentose and Glucuronate Interconversions R_XYLK equation: [c] : atp + xylu-D --> adp + h + xu5p-D
reactant: 222596
product: 222632
reactant: 222584
is: ENSMUSG00000035769.6
is: http://identifiers.org/ec-code/2.7.1.17
product: 222620
name: xylulokinase

222608
type: SpeciesReference
stoichiometry: 1.0
species: 188706

222596
type: SpeciesReference
stoichiometry: 1.0
species: 166904

222632
type: SpeciesReference
stoichiometry: 1.0
species: 175722

222584
type: SpeciesReference
stoichiometry: 1.0
species: 188754

222620
type: SpeciesReference
stoichiometry: 1.0
species: 165387

164258
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: protein-linked serine or threonine residue (O-glycosylation site)_XH

949837
type: Reaction
reactant: 230102
product: 230150
notes: R_MI134PP subsystem: Inositol Phosphate Metabolism R_MI134PP equation: [c] : h2o + mi134p --> mi34p + pi R_MI14PP subsystem: Inositol Phosphate Metabolism R_MI14PP equation: [c] : h2o + mi14p --> mi4p-D + pi
reactant: 230126
is: http://identifiers.org/ec-code/3.1.3.57
is: ENSMUSG00000026102.1
product: 230162
reactant: 230114
reversible: false
fast: false
product: 230138

230102
type: SpeciesReference
stoichiometry: 1.0
species: 180897

230150
type: SpeciesReference
stoichiometry: 2.0
species: 183652

230126
type: SpeciesReference
stoichiometry: 1.0
species: 180945

230162
type: SpeciesReference
stoichiometry: 1.0
species: 181018

181018
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1D-myo-Inositol 4-phosphate_C6H11O9P

230114
type: SpeciesReference
stoichiometry: 2.0
species: 175614

230138
type: SpeciesReference
stoichiometry: 1.0
species: 180994

178918
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 3_C55H89N5O38X

949151
type: Reaction
fast: false
is: ENSMUSG00000000792.1
reactant: 224280
product: 224341
notes: R_UREAt subsystem: Transport, Extracellular R_UREAt equation: urea[e] <==> urea[c] R_NAIt subsystem: Transport, Extracellular R_NAIt equation: i[e] + (2) na1[e] <==> i[c] + (2) na1[c] R_NAt subsystem: Transport, Extracellular R_NAt equation: na1[e] <==> na1[c]
reversible: true
reactant: 224305
reactant: 224293
product: 224329
product: 224317

224280
type: SpeciesReference
stoichiometry: 3.0
species: 181389

224341
type: SpeciesReference
stoichiometry: 1.0
species: 187996

187996
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Urea_CH4N2O

224305
type: SpeciesReference
stoichiometry: 1.0
species: 188008

224293
type: SpeciesReference
stoichiometry: 1.0
species: 177059

177059
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Iodide_I

224329
type: SpeciesReference
stoichiometry: 1.0
species: 177047

224317
type: SpeciesReference
stoichiometry: 3.0
species: 181377

955463
type: Reaction
product: 287500
product: 287464
notes: R_GLCAT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT5g equation: [g] : cs_e_pre2 + udpglcur --> cs_e_pre3 + h + udp R_GLCAT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT3g equation: [g] : cs_c,d,e_pre1 + udpglcur --> cs_c_pre2 + h + udp R_GLCAT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT4g equation: [g] : cs_d_pre2 + udpglcur --> cs_d_pre3 + h + udp R_GLCAT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT2g equation: [g] : cs_a,b,e_pre1 + udpglcur --> cs_a,b_pre2 + h + udp
reactant: 287452
reactant: 287440
product: 287512
product: 287488
reactant: 287404
fast: false
is: ENSMUSG00000038181.7
reversible: false
product: 287524
reactant: 287428
product: 287476
reactant: 287416

287500
type: SpeciesReference
stoichiometry: 4.0
species: 175746

287464
type: SpeciesReference
stoichiometry: 1.0
species: 169321

287452
type: SpeciesReference
stoichiometry: 1.0
species: 169455

169455
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 2_C31H45NO37S4X

287440
type: SpeciesReference
stoichiometry: 4.0
species: 187789

287512
type: SpeciesReference
stoichiometry: 1.0
species: 169467

287488
type: SpeciesReference
stoichiometry: 4.0
species: 187608

287404
type: SpeciesReference
stoichiometry: 1.0
species: 169115

169115
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate C (GalNAc6S-GlcA) and D (GlcNAc6S-GlcA2S), precursor 1_C31H47NO31S2X

287524
type: SpeciesReference
stoichiometry: 1.0
species: 168944

287428
type: SpeciesReference
stoichiometry: 1.0
species: 169309

169309
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate D (GlcNAc6S-GlcA2S) precursor 2_C31H46NO34S3X

287476
type: SpeciesReference
stoichiometry: 1.0
species: 169200

287416
type: SpeciesReference
stoichiometry: 1.0
species: 168932

163499
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _6-Pyruvoyl-5,6,7,8-tetrahydropterin_C9H11N5O3

178581
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate II (core 2-linked), degradation product 3_C58H94N5O46S2X

175674
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: H2O_H2O

954922
type: Reaction
product: 280360
is: ENSMUSG00000038861.6
reversible: false
reactant: 280311
is: ENSMUSG00000025178.7
product: 280347
notes: R_PIK4 subsystem: Glycerophospholipid Metabolism R_PIK4 equation: [c] : atp + pail_hs --> adp + h + pail4p_hs R_PI3P4K subsystem: Inositol Phosphate Metabolism R_PI3P4K equation: [c] : atp + pail3p_hs --> adp + h + pail34p_hs R_PI5P4K subsystem: Inositol Phosphate Metabolism R_PI5P4K equation: [c] : atp + pail5p_hs --> adp + h + pail45p_hs
reactant: 280335
reactant: 280299
reactant: 280323
product: 280397
product: 280372
fast: false
is: http://identifiers.org/ec-code/2.7.1.149
is: http://identifiers.org/ec-code/2.7.1.67
product: 280384

280360
type: SpeciesReference
stoichiometry: 1.0
species: 182887

280311
type: SpeciesReference
stoichiometry: 3.0
species: 166904

280347
type: SpeciesReference
stoichiometry: 1.0
species: 182962

182962
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: phosphatidylinositol 4,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

280335
type: SpeciesReference
stoichiometry: 1.0
species: 182937

182937
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1-Phosphatidyl-1D-myo-inositol 3-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

280299
type: SpeciesReference
stoichiometry: 1.0
species: 183023

183023
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1-Phosphatidyl-1D-myo-inositol 5-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

280323
type: SpeciesReference
stoichiometry: 1.0
species: 183047

183047
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: phosphatidylinositol (homo sapiens)_C9H16O9PFULLRCO2FULLR2CO2

280397
type: SpeciesReference
stoichiometry: 3.0
species: 175722

280372
type: SpeciesReference
stoichiometry: 1.0
species: 182987

182987
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2

280384
type: SpeciesReference
stoichiometry: 3.0
species: 165387

174600
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Glyoxylate_C2H1O3

173101
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550

165797
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: _2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate_C9H12N5O13P3

169151
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 3_C31H48NO32S2

951305
type: Reaction
product: 245022
reversible: true
product: 244998
reactant: 244972
reactant: 244985
is: ENSMUSG00000049624.5
notes: R_GLCURtly subsystem: Transport, Lysosomal R_GLCURtly equation: glcur[c] + h[c] <==> glcur[l] + h[l] R_IDOURtly subsystem: Transport, Lysosomal R_IDOURtly equation: h[c] + idour[c] <==> h[l] + idour[l] R_ACNAMlt subsystem: Transport, Lysosomal R_ACNAMlt equation: acnam[c] + h[c] <==> acnam[l] + h[l]
fast: false
product: 245010
reactant: 244948
reactant: 244960
product: 245034

245022
type: SpeciesReference
stoichiometry: 1.0
species: 174370

174370
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: D-Glucuronate_C6H9O7

244998
type: SpeciesReference
stoichiometry: 1.0
species: 165112

165112
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: N-Acetylneuraminate_C11H18NO9

244972
type: SpeciesReference
stoichiometry: 1.0
species: 165100

165100
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Acetylneuraminate_C11H18NO9

244985
type: SpeciesReference
stoichiometry: 3.0
species: 175722

245010
type: SpeciesReference
stoichiometry: 3.0
species: 175758

244948
type: SpeciesReference
stoichiometry: 1.0
species: 174358

244960
type: SpeciesReference
stoichiometry: 1.0
species: 177143

177143
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Iduronate_C6H9O7

245034
type: SpeciesReference
stoichiometry: 1.0
species: 177155

177155
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: L-Iduronate_C6H9O7

179413
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: lignocericyl coenzyme A_C45H78N7O17P3S

948778
type: Reaction
product: 220329
product: 220305
is: http://identifiers.org/ec-code/4.2.1.22
reversible: false
fast: false
reactant: 220269
notes: R_SELCYSTS subsystem: Selenoamino acid metabolism R_SELCYSTS equation: [c] : selhcys + ser-L --> h2o + selcyst R_CYSTS subsystem: Methionine Metabolism R_CYSTS equation: [c] : hcys-L + ser-L --> cyst-L + h2o
product: 220317
is: ENSMUSG00000024039.6
reactant: 220293
reactant: 220281

220329
type: SpeciesReference
stoichiometry: 2.0
species: 175614

220305
type: SpeciesReference
stoichiometry: 1.0
species: 169731

220269
type: SpeciesReference
stoichiometry: 1.0
species: 175926

220317
type: SpeciesReference
stoichiometry: 1.0
species: 185447

220293
type: SpeciesReference
stoichiometry: 1.0
species: 185459

185459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Selenohomocysteine_C4H9NO2Se

220281
type: SpeciesReference
stoichiometry: 2.0
species: 185532

181174
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol, human uterine homolog_C1245H2040N20O220P20

178810
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate II (core 4-linked), degradation product 1_C78H126N6O64S3X

174454
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Glutamate_C5H8NO4

945663
type: Reaction
product: 193305
name: ornithine carbamoyltransferase, irreversible
product: 193330
is: http://identifiers.org/ec-code/2.1.3.3
reversible: false
is: ENSMUSG00000031173.6
reactant: 193293
product: 193318
notes: R_OCBTm subsystem: Urea cycle/amino group metabolism R_OCBTm equation: [m] : cbp + orn --> citr-L + h + pi
reactant: 193280
fast: false

193305
type: SpeciesReference
stoichiometry: 1.0
species: 183700

193330
type: SpeciesReference
stoichiometry: 1.0
species: 175770

193293
type: SpeciesReference
stoichiometry: 1.0
species: 167627

167627
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Carbamoyl phosphate_CH2NO5P

193318
type: SpeciesReference
stoichiometry: 1.0
species: 168184

168184
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Citrulline_C6H13N3O3

193280
type: SpeciesReference
stoichiometry: 1.0
species: 182683

183532
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Protoheme_C34H30FeN4O4

177918
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 35_C68H113N4O54S1

178473
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 3_C93H152N6O67X

186477
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: tetracosapentaenoyl coenzyme A, n-3_C45H68N7O17P3S

173089
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Ley glycolipid_C56H99N2O30FULLRCO

165689
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _3alpha-Hydroxy-5beta-androstan-17-one_C19H30O2

954081
type: Reaction
reversible: false
reactant: 273742
fast: false
reactant: 273706
notes: R_SR5ARr subsystem: Steroid Metabolism R_SR5ARr equation: [r] : h + nadph + tststerone --> 5adtststerone + nadp R_GALTg subsystem: Chondroitin / heparan sulfate biosynthesis R_GALTg equation: [g] : udpgal + xser --> h + lxser + udp R_SR5AR2r subsystem: Steroid Metabolism R_SR5AR2r equation: [r] : andrstndn + h + nadph --> andrstandn + nadp
is: http://identifiers.org/ec-code/2.4.1.133
reactant: 273694
product: 273766
is: ENSMUSG00000038541.6
product: 273790
product: 273814
product: 273802
product: 273826
reactant: 273754
reactant: 273718
is: http://identifiers.org/ec-code/1.3.99.5
product: 273778
reactant: 273730

273742
type: SpeciesReference
stoichiometry: 1.0
species: 187765

187765
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: UDPgalactose_C15H22N2O17P2

273706
type: SpeciesReference
stoichiometry: 2.0
species: 181667

273694
type: SpeciesReference
stoichiometry: 1.0
species: 188646

273766
type: SpeciesReference
stoichiometry: 1.0
species: 187608

273790
type: SpeciesReference
stoichiometry: 1.0
species: 179835

179835
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Gal-Xyl-L-Ser (protein)_C11H19O9X

273814
type: SpeciesReference
stoichiometry: 2.0
species: 181607

273802
type: SpeciesReference
stoichiometry: 1.0
species: 166303

273826
type: SpeciesReference
stoichiometry: 1.0
species: 162919

162919
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _5alpha-Dihydrotestosterone_C19H30O2

273754
type: SpeciesReference
stoichiometry: 2.0
species: 175794

273718
type: SpeciesReference
stoichiometry: 1.0
species: 187332

273778
type: SpeciesReference
stoichiometry: 1.0
species: 175746

273730
type: SpeciesReference
stoichiometry: 1.0
species: 166315

166315
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Androstenedione_C19H26O2

169043
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), degradation product 1_C45H67N2O46S3

951064
type: Reaction
product: 243477
notes: R_SRTNMTX subsystem: Tryptophan metabolism R_SRTNMTX equation: [c] : amet + srtn --> ahcys + h + nmthsrtn
reactant: 243453
product: 243501
reactant: 243465
is: http://identifiers.org/ec-code/2.1.1.49
fast: false
reversible: false
product: 243489
is: ENSMUSG00000003477.4
name: S-Adenosyl-L-methionine:amine N-methyltransferase (srtn)

243477
type: SpeciesReference
stoichiometry: 1.0
species: 165737

243453
type: SpeciesReference
stoichiometry: 1.0
species: 166159

243501
type: SpeciesReference
stoichiometry: 1.0
species: 175722

243465
type: SpeciesReference
stoichiometry: 1.0
species: 185897

243489
type: SpeciesReference
stoichiometry: 1.0
species: 181959

170278
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Dodecanoyl-ACP (n-C12:0ACP)_C23H43N2O8PRS

184230
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: pristanal_C19H38O

175866
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: hyaluronan biosynthesis, precursor 1_C14H20NO11

952231
type: Reaction
is: ENSMUSG00000038855.7
reactant: 253884
reactant: 253896
is: ENSMUSG00000027296.6
product: 253908
is: http://identifiers.org/ec-code/2.7.1.127
reversible: false
product: 253932
product: 253920
notes: R_MI145PK subsystem: Inositol Phosphate Metabolism R_MI145PK equation: [c] : atp + mi145p --> adp + h + mi1345p
is: ENSMUSG00000003752.7
name: inositol-1,4,5-trisphosphate 3-kinase
fast: false

253884
type: SpeciesReference
stoichiometry: 1.0
species: 166904

253896
type: SpeciesReference
stoichiometry: 1.0
species: 180921

253908
type: SpeciesReference
stoichiometry: 1.0
species: 180861

253932
type: SpeciesReference
stoichiometry: 1.0
species: 175722

253920
type: SpeciesReference
stoichiometry: 1.0
species: 165387

947396
type: Reaction
notes: R_GLUCYS subsystem: Glutathione Metabolism R_GLUCYS equation: [c] : atp + cys-L + glu-L --> adp + glucys + h + pi
reactant: 208939
name: gamma-glutamylcysteine synthetase
is: ENSMUSG00000028124.6
product: 208988
reactant: 208915
reversible: false
is: ENSMUSG00000032350.7
is: http://identifiers.org/ec-code/6.3.2.2
product: 208976
fast: false
product: 208951
reactant: 208927
product: 208963

208939
type: SpeciesReference
stoichiometry: 1.0
species: 174442

208988
type: SpeciesReference
stoichiometry: 1.0
species: 175722

208915
type: SpeciesReference
stoichiometry: 1.0
species: 169680

208976
type: SpeciesReference
stoichiometry: 1.0
species: 165387

208951
type: SpeciesReference
stoichiometry: 1.0
species: 183652

208927
type: SpeciesReference
stoichiometry: 1.0
species: 166904

208963
type: SpeciesReference
stoichiometry: 1.0
species: 174516

174516
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: gamma-L-Glutamyl-L-cysteine_C8H13N2O5S

956161
type: Reaction
reactant: 293801
product: 293849
is: http://identifiers.org/ec-code/2.5.1.22
product: 293837
fast: false
name: spermine synthase
reactant: 293813
reversible: false
product: 293825
notes: R_SPRMS subsystem: Urea cycle/amino group metabolism R_SPRMS equation: [c] : ametam + spmd --> 5mta + h + sprm
is: ENSMUSG00000071708.3

293801
type: SpeciesReference
stoichiometry: 1.0
species: 185861

185861
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Spermidine_C7H22N3

293849
type: SpeciesReference
stoichiometry: 1.0
species: 175722

293837
type: SpeciesReference
stoichiometry: 1.0
species: 185873

293813
type: SpeciesReference
stoichiometry: 1.0
species: 166207

293825
type: SpeciesReference
stoichiometry: 1.0
species: 163269

179026
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: de-Fuc, reducing GlcNAc removed, de-Sia form of PA6 (w/o peptide linkage)_C54H91N3O41

945742
type: Reaction
modifier: 194116
is: ENSMUSG00000025190.6
modifier: 194092
modifier: 194164
modifier: 194128
modifier: 194177
fast: false
reactant: 194008
product: 194020
reactant: 193984
reactant: 193972
modifier: 194140
modifier: 194080
product: 194044
reversible: false
modifier: 194104
reactant: 193996
modifier: 194056
is: http://identifiers.org/ec-code/2.6.1.58
is: http://identifiers.org/ec-code/2.6.1.1
product: 194032
is: http://identifiers.org/ec-code/2.6.1.3
modifier: 194068
modifier: 194189
notes: R_EHGLAT subsystem: Arginine and Proline Metabolism R_EHGLAT equation: [c] : akg + e4hglu --> 4h2oglt + glu-L R_LCYSTAT subsystem: Cysteine Metabolism R_LCYSTAT equation: [c] : Lcyst + akg <==> 3spyr + glu-L R_CYSTA subsystem: Cysteine Metabolism R_CYSTA equation: [c] : akg + cys-L <==> glu-L + mercppyr R_ASPTA subsystem: Alanine and Aspartate Metabolism R_ASPTA equation: [c] : akg + asp-L <==> glu-L + oaa R_3SALATAi subsystem: Cysteine Metabolism R_3SALATAi equation: [c] : 3sala + akg + h --> 3snpyr + glu-L R_TYRTA subsystem: Tyrosine metabolism R_TYRTA equation: [c] : akg + tyr-L <==> 34hpp + glu-L R_PHETA1 subsystem: Phenylalanine metabolism R_PHETA1 equation: [c] : akg + phe-L <==> glu-L + phpyr
modifier: 194152
is: http://identifiers.org/ec-code/2.6.1.5

163775
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Cysteate_C3H6NO5S

194008
type: SpeciesReference
stoichiometry: 1.0
species: 162266

194020
type: SpeciesReference
stoichiometry: 2.0
species: 174442

193984
type: SpeciesReference
stoichiometry: 1.0
species: 171872

171872
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-erythro-4-Hydroxyglutamate_C5H8NO5

193972
type: SpeciesReference
stoichiometry: 2.0
species: 165871

194044
type: SpeciesReference
stoichiometry: 1.0
species: 162290

162290
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Sulfinopyruvate_C3H2O5S

193996
type: SpeciesReference
stoichiometry: 1.0
species: 175722

194032
type: SpeciesReference
stoichiometry: 1.0
species: 162532

162532
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-Hydroxy-2-oxoglutarate_C5H4O6

180692
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Mercaptopyruvate_C3H3O3S

178702
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 1_C33H53N3O23X

183265
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: propionyl-carnitine_C10H19NO4

174346
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: D-Glucarate_C6H8O8

161830
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Hydroxyanthranilate_C7H7NO3

172161
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: estradiol glucuronide_C24H32O8

955909
type: Reaction
is: http://identifiers.org/ec-code/3.1.1.4
product: 291727
reactant: 291678
product: 291715
is: ENSMUSG00000041202.5
is: ENSMUSG00000041193.6
reactant: 291691
is: ENSMUSG00000022683.6
name: phospholipase A2
fast: false
notes: R_PLA2_2e subsystem: Glycerophospholipid Metabolism R_PLA2_2e equation: [e] : h2o + pchol_hs --> Rtotal2 + h + lpchol_hs
is: ENSMUSG00000028749.6
is: ENSMUSG00000029522.5
reversible: false
is: ENSMUSG00000027999.7
is: ENSMUSG00000028751.6
product: 291703

291727
type: SpeciesReference
stoichiometry: 1.0
species: 163992

163992
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: R total 2 position_CO2FULLR2

291678
type: SpeciesReference
stoichiometry: 1.0
species: 183167

183167
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2

291715
type: SpeciesReference
stoichiometry: 1.0
species: 175734

291691
type: SpeciesReference
stoichiometry: 1.0
species: 175626

291703
type: SpeciesReference
stoichiometry: 1.0
species: 179799

179799
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: lysophosphatidylcholine (homo sapiens)_C8H19NO5PFULLRCO2

177603
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 12_C174H279N12O153S9

955655
type: Reaction
notes: R_AHANDROSTANGLCte subsystem: Transport, Extracellular R_AHANDROSTANGLCte equation: ahandrostanglc[c] + atp[c] + h2o[c] --> adp[c] + ahandrostanglc[e] + h[c] + pi[c] R_5ADTSTSTERONEGLCte subsystem: Transport, Extracellular R_5ADTSTSTERONEGLCte equation: _5adtststeroneglc[c] + atp[c] + h2o[c] --> 5adtststeroneglc[e] + adp[c] + h[c] + pi[c] R_BILDGLCURte subsystem: Transport, Extracellular R_BILDGLCURte equation: atp[c] + bildglcur[c] + h2o[c] <==> adp[c] + bildglcur[e] + h[c] + pi[c] R_BILGLCURte subsystem: Transport, Extracellular R_BILGLCURte equation: atp[c] + bilglcur[c] + h2o[c] <==> adp[c] + bilglcur[e] + h[c] + pi[c] R_TSTSTERONEGLCte subsystem: Transport, Extracellular R_TSTSTERONEGLCte equation: atp[c] + h2o[c] + tststeroneglc[c] --> adp[c] + h[c] + pi[c] + tststeroneglc[e] R_ANDRSTRNGLCte subsystem: Transport, Extracellular R_ANDRSTRNGLCte equation: andrstrnglc[c] + atp[c] + h2o[c] --> adp[c] + andrstrnglc[e] + h[c] + pi[c] R_ESTRIOLGLCte subsystem: Transport, Extracellular R_ESTRIOLGLCte equation: atp[c] + estriolglc[c] + h2o[c] --> adp[c] + estriolglc[e] + h[c] + pi[c]
modifier: 289712
product: 289591
fast: false
reactant: 289542
product: 289579
modifier: 289724
reactant: 289517
reversible: false
reactant: 289504
product: 289627
product: 289615
modifier: 289688
modifier: 289748
modifier: 289676
product: 289652
is: ENSMUSG00000023088.7
reactant: 289554
product: 289640
modifier: 289700
modifier: 289772
modifier: 289736
reactant: 289491
product: 289664
modifier: 289760
product: 289603
reactant: 289530
reactant: 289566
is: ENSMUSG00000079736.1

167073
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Bilirubin beta-diglucuronide_C45H50N4O18

289591
type: SpeciesReference
stoichiometry: 1.0
species: 162943

289542
type: SpeciesReference
stoichiometry: 1.0
species: 172209

172209
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _16-Glucuronide-estriol_C24H32O9

289579
type: SpeciesReference
stoichiometry: 1.0
species: 172221

172221
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: _16-Glucuronide-estriol_C24H32O9

289517
type: SpeciesReference
stoichiometry: 1.0
species: 165701

165701
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Etiocholan-3alpha-ol-17-one 3-glucuronide_C25H38O8

289504
type: SpeciesReference
stoichiometry: 5.0
species: 166904

289627
type: SpeciesReference
stoichiometry: 1.0
species: 187356

187356
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: testosterone glucuronide_C25H36O8

289615
type: SpeciesReference
stoichiometry: 5.0
species: 183652

167109
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Bilirubin monoglucuronide_C39H44N4O12

167121
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Bilirubin monoglucuronide_C39H44N4O12

289652
type: SpeciesReference
stoichiometry: 1.0
species: 166351

289554
type: SpeciesReference
stoichiometry: 1.0
species: 166339

166339
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: androsterone glucuronide_C25H38O8

289640
type: SpeciesReference
stoichiometry: 5.0
species: 165387

289491
type: SpeciesReference
stoichiometry: 1.0
species: 162931

162931
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5alpha-Dihydrotestosterone glucuronide_C25H38O8

289664
type: SpeciesReference
stoichiometry: 5.0
species: 175722

167085
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Bilirubin beta-diglucuronide_C45H50N4O18

289603
type: SpeciesReference
stoichiometry: 1.0
species: 165713

289530
type: SpeciesReference
stoichiometry: 1.0
species: 187344

187344
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: testosterone glucuronide_C25H36O8

289566
type: SpeciesReference
stoichiometry: 5.0
species: 175614

951533
type: Reaction
product: 246807
product: 246856
reactant: 246709
product: 246794
is: ENSMUSG00000062478.6
product: 246868
product: 246820
reactant: 246745
reactant: 246673
reactant: 246733
reactant: 246697
reactant: 246685
product: 246781
notes: R_FUT15g subsystem: Blood Group Biosynthesis R_FUT15g equation: [g] : galacgalfuc12gal14acglcgalgluside_hs + gdpfuc --> fucgalacgalfuc12gal14acglcgalgluside_hs + gdp + h R_FUT12g subsystem: Blood Group Biosynthesis R_FUT12g equation: [g] : galacglcgalgluside_hs + gdpfuc --> fucgalacglcgalgluside_hs + gdp + h R_FUT17g subsystem: Blood Group Biosynthesis R_FUT17g equation: [g] : galacgalfucgalacglcgal14acglcgalgluside_hs + gdpfuc --> fucgalacgalfucgalacglcgal14acglcgalgluside_hs + gdp + h R_FUT16g subsystem: Blood Group Biosynthesis R_FUT16g equation: [g] : galacglcgal14acglcgalgluside_hs + gdpfuc --> fucgalacglcgal14acglcgalgluside_hs + gdp + h R_FUT11g subsystem: Sphingolipid Metabolism R_FUT11g equation: [g] : galgbside_hs + gdpfuc --> fucgalgbside_hs + gdp + h R_FUT18g subsystem: Blood Group Biosynthesis R_FUT18g equation: [g] : galacglcgalacglcgal14acglcgalgluside_hs + (2) gdpfuc --> fucfucgalacglcgalacglcgal14acglcgalgluside_hs + (2) gdp + (2) h R_FUT14g subsystem: Blood Group Biosynthesis R_FUT14g equation: [g] : gal14acglcgalgluside_hs + gdpfuc --> fuc12gal14acglcgalgluside_hs + gdp + h
product: 246844
is: http://identifiers.org/ec-code/2.4.1.69
fast: false
reactant: 246757
reversible: false
product: 246769
reactant: 246721
product: 246832

246807
type: SpeciesReference
stoichiometry: 8.0
species: 175746

246856
type: SpeciesReference
stoichiometry: 1.0
species: 173197

173197
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Type IIIH glycolipid_C70H122N3O40FULLRCO

246709
type: SpeciesReference
stoichiometry: 1.0
species: 173631

246794
type: SpeciesReference
stoichiometry: 1.0
species: 173245

173245
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Type IH glycolipid_C50H89N2O26FULLRCO

246868
type: SpeciesReference
stoichiometry: 1.0
species: 173161

173161
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)2 (Cer)1_C84H145N4O50FULLRCO

246820
type: SpeciesReference
stoichiometry: 8.0
species: 174142

174142
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GDP_C10H12N5O11P2

246745
type: SpeciesReference
stoichiometry: 1.0
species: 173667

173667
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: I-antigen_C72H125N4O42FULLRCO

246673
type: SpeciesReference
stoichiometry: 1.0
species: 173557

246733
type: SpeciesReference
stoichiometry: 1.0
species: 173619

173619
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (Gal)3 (GalNAc)1 (Glc)1 (GlcNAc)1 (LFuc)1 (Cer)1_C64H112N3O36FULLRCO

246697
type: SpeciesReference
stoichiometry: 1.0
species: 173691

173691
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Lc4Cer_C44H79N2O22FULLRCO

246685
type: SpeciesReference
stoichiometry: 1.0
species: 173777

173777
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: galactosylgloboside (homo sapiens)_C50H89N2O27FULLRCO

246781
type: SpeciesReference
stoichiometry: 1.0
species: 173269

173269
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: fucosyl galactosylgloboside (homo sapiens)_C56H99N2O31FULLRCO

246844
type: SpeciesReference
stoichiometry: 1.0
species: 172956

172956
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Type IIH glycolipid_C50H89N2O26FULLRCO

246757
type: SpeciesReference
stoichiometry: 1.0
species: 173655

246769
type: SpeciesReference
stoichiometry: 1.0
species: 173209

173209
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (Gal)4 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)2 (Cer)1_C84H145N4O50FULLRCO

246721
type: SpeciesReference
stoichiometry: 8.0
species: 174202

246832
type: SpeciesReference
stoichiometry: 1.0
species: 173233

946940
type: Reaction
reversible: false
reactant: 204942
is: ENSMUSG00000030283.2
reactant: 204954
is: http://identifiers.org/ec-code/2.4.99.8
notes: R_ST8SIA12 subsystem: Sphingolipid Metabolism R_ST8SIA12 equation: [g] : cmpacna + gm3_hs --> cmp + gd3_hs + h R_ST8SIA11 subsystem: Sphingolipid Metabolism R_ST8SIA11 equation: [g] : acngalgbside_hs + cmpacna --> acnacngalgbside_hs + cmp + h
reactant: 204966
product: 205014
fast: false
product: 204978
product: 205002
product: 204990

204942
type: SpeciesReference
stoichiometry: 2.0
species: 168388

204954
type: SpeciesReference
stoichiometry: 1.0
species: 165184

165184
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: sialyl galactosylgloboside (homo sapiens)_C61H105N3O35FULLRCO

204966
type: SpeciesReference
stoichiometry: 1.0
species: 174974

205014
type: SpeciesReference
stoichiometry: 1.0
species: 174094

204978
type: SpeciesReference
stoichiometry: 2.0
species: 175746

205002
type: SpeciesReference
stoichiometry: 2.0
species: 168340

204990
type: SpeciesReference
stoichiometry: 1.0
species: 165088

165088
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: disialyl galactosylgloboside (homo sapiens)_C72H121N4O43FULLRCO

953841
type: Reaction
reversible: false
product: 270447
is: ENSMUSG00000008763.6
product: 270435
reactant: 270339
reactant: 270327
reactant: 270375
product: 270484
reactant: 270351
is: http://identifiers.org/ec-code/3.2.1.113
reactant: 270303
product: 270471
reactant: 270423
reactant: 270399
product: 270496
reactant: 270363
product: 270544
product: 270532
reactant: 270387
product: 270508
product: 270520
notes: R_MM5bg subsystem: N-Glycan Biosynthesis R_MM5bg equation: [g] : h2o + m5masnB1 --> m4masn + man R_MM7Cbg subsystem: N-Glycan Biosynthesis R_MM7Cbg equation: [g] : h2o + m7masnC --> m6masnC + man R_MM6B2g subsystem: N-Glycan Biosynthesis R_MM6B2g equation: [g] : h2o + m6masnB2 --> m5masnB2 + man R_MM6bg subsystem: N-Glycan Biosynthesis R_MM6bg equation: [g] : h2o + m6masnC --> m5masnC + man R_MM8Ag subsystem: N-Glycan Biosynthesis R_MM8Ag equation: [g] : h2o + m8masn --> m7masnA + man R_MM8Cg subsystem: N-Glycan Biosynthesis R_MM8Cg equation: [g] : h2o + m8masn --> m7masnC + man R_MM7Cag subsystem: N-Glycan Biosynthesis R_MM7Cag equation: [g] : h2o + m7masnA --> m6masnC + man R_MM6B1ag subsystem: N-Glycan Biosynthesis R_MM6B1ag equation: [g] : h2o + m6masnB1 --> m5masnB1 + man R_MM7B2g subsystem: N-Glycan Biosynthesis R_MM7B2g equation: [g] : h2o + m7masnB --> m6masnB2 + man R_MM6B1bg subsystem: N-Glycan Biosynthesis R_MM6B1bg equation: [g] : h2o + m6masnB2 --> m5masnB1 + man R_MM5ag subsystem: N-Glycan Biosynthesis R_MM5ag equation: [g] : h2o + m5masnC --> m4masn + man R_MM5cg subsystem: N-Glycan Biosynthesis R_MM5cg equation: [g] : h2o + m5masnB2 --> m4masn + man R_MM7B1g subsystem: N-Glycan Biosynthesis R_MM7B1g equation: [g] : h2o + m7masnB --> m6masnB1 + man
reactant: 270411
fast: false
product: 270459
reactant: 270315

270447
type: SpeciesReference
stoichiometry: 1.0
species: 180040

270435
type: SpeciesReference
stoichiometry: 3.0
species: 179992

270339
type: SpeciesReference
stoichiometry: 1.0
species: 180198

270327
type: SpeciesReference
stoichiometry: 1.0
species: 180052

270375
type: SpeciesReference
stoichiometry: 1.0
species: 180125

270484
type: SpeciesReference
stoichiometry: 1.0
species: 180101

270351
type: SpeciesReference
stoichiometry: 13.0
species: 175638

270303
type: SpeciesReference
stoichiometry: 2.0
species: 180173

270471
type: SpeciesReference
stoichiometry: 1.0
species: 180198

270423
type: SpeciesReference
stoichiometry: 1.0
species: 180028

270399
type: SpeciesReference
stoichiometry: 2.0
species: 180113

270496
type: SpeciesReference
stoichiometry: 2.0
species: 180125

270363
type: SpeciesReference
stoichiometry: 1.0
species: 180101

270544
type: SpeciesReference
stoichiometry: 2.0
species: 180028

270532
type: SpeciesReference
stoichiometry: 13.0
species: 180536

270387
type: SpeciesReference
stoichiometry: 1.0
species: 180161

270508
type: SpeciesReference
stoichiometry: 1.0
species: 180161

270520
type: SpeciesReference
stoichiometry: 1.0
species: 180113

270411
type: SpeciesReference
stoichiometry: 2.0
species: 180234

270459
type: SpeciesReference
stoichiometry: 1.0
species: 180052

270315
type: SpeciesReference
stoichiometry: 1.0
species: 180040

955415
type: Reaction
product: 285510
product: 285571
product: 285546
product: 285583
reactant: 285438
product: 285522
reactant: 285462
reactant: 285450
fast: false
reversible: true
reactant: 285390
product: 285619
product: 285607
notes: R_SERGLYexR subsystem: Transport, Extracellular R_SERGLYexR equation: gly[c] + ser-L[e] <==> gly[e] + ser-L[c] R_THRGLNexR subsystem: Transport, Extracellular R_THRGLNexR equation: gln-L[c] + thr-L[e] <==> gln-L[e] + thr-L[c] R_ALAGLYexR subsystem: Transport, Extracellular R_ALAGLYexR equation: ala-L[e] + gly[c] <==> ala-L[c] + gly[e] R_SERGLNexR subsystem: Transport, Extracellular R_SERGLNexR equation: gln-L[c] + ser-L[e] <==> gln-L[e] + ser-L[c] R_THRGLYexR subsystem: Transport, Extracellular R_THRGLYexR equation: gly[c] + thr-L[e] <==> gly[e] + thr-L[c] R_ALADGLNexR subsystem: Transport, Extracellular R_ALADGLNexR equation: ala-D[e] + gln-L[c] <==> ala-D[c] + gln-L[e] R_CYSGLUexR subsystem: Transport, Extracellular R_CYSGLUexR equation: cys-L[e] + gln-L[c] <==> cys-L[c] + gln-L[e] R_SERDGLNexR subsystem: Transport, Extracellular R_SERDGLNexR equation: gln-L[c] + ser-D[e] <==> gln-L[e] + ser-D[c] R_ALADGLYexR subsystem: Transport, Extracellular R_ALADGLYexR equation: ala-D[e] + gly[c] <==> ala-D[c] + gly[e] R_SERDGLYexR subsystem: Transport, Extracellular R_SERDGLYexR equation: gly[c] + ser-D[e] <==> gly[e] + ser-D[c] R_ALAGLNexR subsystem: Transport, Extracellular R_ALAGLNexR equation: ala-L[e] + gln-L[c] <==> ala-L[c] + gln-L[e] R_CYSGLYexR subsystem: Transport, Extracellular R_CYSGLYexR equation: cys-L[c] + gly[e] <==> cys-L[e] + gly[c]
reactant: 285426
reactant: 285498
reactant: 285486
is: ENSMUSG00000030495.4
product: 285558
reactant: 285414
reactant: 285402
reactant: 285474
product: 285534
product: 285595

285510
type: SpeciesReference
stoichiometry: 1.0
species: 174625

285571
type: SpeciesReference
stoichiometry: 2.0
species: 186936

285546
type: SpeciesReference
stoichiometry: 1.0
species: 169693

169693
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Cysteine_C3H7NO2S

285583
type: SpeciesReference
stoichiometry: 6.0
species: 174394

285438
type: SpeciesReference
stoichiometry: 2.0
species: 166027

285522
type: SpeciesReference
stoichiometry: 1.0
species: 169680

285462
type: SpeciesReference
stoichiometry: 6.0
species: 174382

285450
type: SpeciesReference
stoichiometry: 1.0
species: 169693

285390
type: SpeciesReference
stoichiometry: 2.0
species: 165979

165979
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: D-Alanine_C3H7NO2

285619
type: SpeciesReference
stoichiometry: 2.0
species: 165967

285607
type: SpeciesReference
stoichiometry: 2.0
species: 166015

285426
type: SpeciesReference
stoichiometry: 1.0
species: 169680

285498
type: SpeciesReference
stoichiometry: 2.0
species: 185544

285486
type: SpeciesReference
stoichiometry: 2.0
species: 186948

285558
type: SpeciesReference
stoichiometry: 5.0
species: 174637

285414
type: SpeciesReference
stoichiometry: 5.0
species: 174625

285402
type: SpeciesReference
stoichiometry: 2.0
species: 185520

285474
type: SpeciesReference
stoichiometry: 1.0
species: 174637

285534
type: SpeciesReference
stoichiometry: 2.0
species: 185532

285595
type: SpeciesReference
stoichiometry: 2.0
species: 185508

185508
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Serine_C3H7NO3

167531
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: L-Carnosine_C9H14N4O3

186065
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: stearidonyl carnitine_C25H41NO4

954766
type: Reaction
is: http://identifiers.org/ec-code/2.3.1.57
product: 279430
name: Putrescine acetyltransferase
fast: false
is: ENSMUSG00000069835.3
product: 279454
reactant: 279418
reversible: false
notes: R_PTRCAT1 subsystem: Arginine and Proline Metabolism R_PTRCAT1 equation: [c] : accoa + ptrc --> aprut + coa + h
reactant: 279406
product: 279442
is: ENSMUSG00000025283.8
is: ENSMUSG00000025527.1

279430
type: SpeciesReference
stoichiometry: 1.0
species: 168509

279454
type: SpeciesReference
stoichiometry: 1.0
species: 166495

279418
type: SpeciesReference
stoichiometry: 1.0
species: 184699

279406
type: SpeciesReference
stoichiometry: 1.0
species: 164583

279442
type: SpeciesReference
stoichiometry: 1.0
species: 175722

161016
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _17alpha-Hydroxyprogesterone_C21H30O3

181776
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Ammonium_H4N

954189
type: Reaction
reactant: 274466
product: 274478
notes: R_HIBDm subsystem: Valine, Leucine, and Isoleucine Metabolism R_HIBDm equation: [m] : 3hmp + nad <==> 2mop + h + nadh
fast: false
is: ENSMUSG00000029776.7
name: _3-hydroxyisobutyrate dehydrogenase, mitochondrial
is: http://identifiers.org/ec-code/1.1.1.31
product: 274502
reversible: true
product: 274490
reactant: 274454

274466
type: SpeciesReference
stoichiometry: 1.0
species: 181461

274478
type: SpeciesReference
stoichiometry: 1.0
species: 161453

274502
type: SpeciesReference
stoichiometry: 1.0
species: 181522

274490
type: SpeciesReference
stoichiometry: 1.0
species: 175770

274454
type: SpeciesReference
stoichiometry: 1.0
species: 161903

161903
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3-Hydroxy-2-methylpropanoate_C4H7O3

948682
type: Reaction
product: 219715
reactant: 219703
product: 219727
fast: false
is: ENSMUSG00000018846.7
product: 219739
is: ENSMUSG00000029056.6
reversible: false
is: http://identifiers.org/ec-code/2.7.1.33
is: ENSMUSG00000033610.7
name: pantothenate kinase
notes: R_PNTK subsystem: CoA Biosynthesis R_PNTK equation: [c] : atp + pnto-R --> 4ppan + adp + h
reactant: 219691

219715
type: SpeciesReference
stoichiometry: 1.0
species: 165387

219703
type: SpeciesReference
stoichiometry: 1.0
species: 166904

219727
type: SpeciesReference
stoichiometry: 1.0
species: 162761

219739
type: SpeciesReference
stoichiometry: 1.0
species: 175722

219691
type: SpeciesReference
stoichiometry: 1.0
species: 183808

183808
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: (R)-Pantothenate_C9H16NO5

183628
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: phytanyl coa_C41H70N7O17P3S

950282
type: Reaction
notes: R_GPIMTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIMTer_L equation: [r] : (0.1) dolmanp_L + gacpail_hs --> (0.1) dolp_L + h + mgacpail_hs R_GPIMTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIMTer_U equation: [r] : (0.1) dolmanp_U + gacpail_hs --> (0.1) dolp_U + h + mgacpail_hs
product: 236391
reactant: 236355
reactant: 236342
product: 236403
fast: false
reversible: false
is: ENSMUSG00000050229.1
is: ENSMUSG00000023791.5
product: 236379
product: 236415
reactant: 236367

236391
type: SpeciesReference
stoichiometry: 1.0
species: 171439

236355
type: SpeciesReference
stoichiometry: 1.0
species: 171367

171367
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Dolichyl phosphate D-mannose, human liver homolog_C1140H1868O90P10

236342
type: SpeciesReference
stoichiometry: 1.0
species: 171391

171391
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Dolichyl phosphate D-mannose, human uterine homolog_C1085H1780O90P10

236403
type: SpeciesReference
stoichiometry: 2.0
species: 180812

180812
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: mannosyl-glucosaminyl-acylphosphatidylinositiol (H2)_C37H68NO19PFULLRCO2FULLR2CO2

236379
type: SpeciesReference
stoichiometry: 1.0
species: 171415

236415
type: SpeciesReference
stoichiometry: 2.0
species: 175794

236367
type: SpeciesReference
stoichiometry: 2.0
species: 173545

173545
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526

176698
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 5_C67H97N4O86S10

162835
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-Trimethylammoniobutanoate_C7H15NO2

172053
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Elaidic carnitine_C25H47NO4

175046
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GlcNAc-alpha-1,4-Core 1_C22H37N2O15X

185642
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Sulfite_O3S

954718
type: Reaction
product: 279142
is: ENSMUSG00000000171.3
is: ENSMUSG00000058076.5
product: 279130
reactant: 279117
is: http://identifiers.org/ec-code/1.3.99.1
is: ENSMUSG00000021577.6
is: ENSMUSG00000009863.7
reactant: 279105
reversible: true
notes: R_SUCD1m subsystem: Citric Acid Cycle R_SUCD1m equation: [m] : fad + succ <==> fadh2 + fum
fast: false
name: succinate dehydrogenase

279142
type: SpeciesReference
stoichiometry: 1.0
species: 173293

173293
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Fumarate_C4H2O4

279130
type: SpeciesReference
stoichiometry: 1.0
species: 172547

279117
type: SpeciesReference
stoichiometry: 1.0
species: 172499

279105
type: SpeciesReference
stoichiometry: 1.0
species: 186101

954465
type: Reaction
fast: false
reactant: 276759
reversible: true
name: glycine reversible transport via sodium and chloride symport (3:1:1)
product: 276771
product: 276783
product: 276795
is: ENSMUSG00000039728.7
reactant: 276734
reactant: 276747
notes: R_GLYt7_LPAREN_311_RPAREN_r subsystem: Transport, Extracellular R_GLYt7_LPAREN_311_RPAREN_r equation: cl[e] + gly[e] + (3) na1[e] <==> cl[c] + gly[c] + (3) na1[c]

276759
type: SpeciesReference
stoichiometry: 1.0
species: 168208

276771
type: SpeciesReference
stoichiometry: 1.0
species: 174625

276783
type: SpeciesReference
stoichiometry: 1.0
species: 168196

276795
type: SpeciesReference
stoichiometry: 3.0
species: 181377

276734
type: SpeciesReference
stoichiometry: 3.0
species: 181389

276747
type: SpeciesReference
stoichiometry: 1.0
species: 174637

946156
type: Reaction
product: 197660
reversible: false
is: ENSMUSG00000025270.6
is: ENSMUSG00000032786.7
reactant: 197624
product: 197685
product: 197673
notes: R_ALASm subsystem: Glycine, Serine, and Threonine Metabolism R_ALASm equation: [m] : gly + h + succoa --> 5aop + co2 + coa
name: _5-aminolevulinate synthase
fast: false
reactant: 197636
reactant: 197648
is: http://identifiers.org/ec-code/2.3.1.37

197660
type: SpeciesReference
stoichiometry: 1.0
species: 163003

163003
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _5-Amino-4-oxopentanoate_C5H9NO3

197624
type: SpeciesReference
stoichiometry: 1.0
species: 186138

197685
type: SpeciesReference
stoichiometry: 1.0
species: 168461

197673
type: SpeciesReference
stoichiometry: 1.0
species: 168545

197636
type: SpeciesReference
stoichiometry: 1.0
species: 174661

197648
type: SpeciesReference
stoichiometry: 1.0
species: 175770

953217
type: Reaction
is: ENSMUSG00000032942.7
fast: false
product: 265184
is: ENSMUSG00000031710.2
notes: R_Htm subsystem: Transport, Mitochondrial R_Htm equation: h[c] --> h[m]
is: ENSMUSG00000023912.7
reversible: false
name: Uncoupling protein
is: ENSMUSG00000033685.4
reactant: 265172

265184
type: SpeciesReference
stoichiometry: 1.0
species: 175770

265172
type: SpeciesReference
stoichiometry: 1.0
species: 175722

188442
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al_C27H46O3

167423
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: cervonyl carnitine_C29H45NO4

181138
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: beta-1,4-mannose-N-acetylglucosamine_C14H25NO11

173281
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Fumarate_C4H2O4

184735
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Pyridoxamine 5'-phosphate_C8H12N2O5P

953385
type: Reaction
is: ENSMUSG00000050345.7
product: 266610
is: ENSMUSG00000074874.2
product: 266573
reactant: 266549
is: http://identifiers.org/ec-code/3.6.1.1
is: http://identifiers.org/ec-code/3.1.3.9
is: ENSMUSG00000021439.6
product: 266634
reactant: 266561
notes: R_PPAer subsystem: Miscellaneous R_PPAer equation: [r] : h2o + ppi --> h + (2) pi R_G6PPer subsystem: Glycolysis/Gluconeogenesis R_G6PPer equation: [r] : g6p + h2o --> glc-D + pi R_CBPPer subsystem: Glycolysis/Gluconeogenesis R_CBPPer equation: [r] : cbp + glc-D + h --> co2 + g6p + nh4
reactant: 266537
is: ENSMUSG00000034793.8
is: ENSMUSG00000044258.8
reversible: false
is: ENSMUSG00000042243.7
is: ENSMUSG00000074871.1
product: 266622
product: 266586
reactant: 266525
is: ENSMUSG00000021440.6
is: ENSMUSG00000055298.4
is: ENSMUSG00000021441.3
is: ENSMUSG00000055679.4
reactant: 266513
is: ENSMUSG00000021477.6
is: ENSMUSG00000074870.2
product: 266598
reactant: 266501
is: ENSMUSG00000005232.4
fast: false
is: ENSMUSG00000056728.5
is: ENSMUSG00000057446.2

266610
type: SpeciesReference
stoichiometry: 1.0
species: 181801

181801
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Ammonium_H4N

266573
type: SpeciesReference
stoichiometry: 3.0
species: 183724

266549
type: SpeciesReference
stoichiometry: 1.0
species: 174322

174322
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: D-Glucose_C6H12O6

266634
type: SpeciesReference
stoichiometry: 1.0
species: 175794

266561
type: SpeciesReference
stoichiometry: 1.0
species: 175794

266537
type: SpeciesReference
stoichiometry: 2.0
species: 175686

266622
type: SpeciesReference
stoichiometry: 1.0
species: 174322

266586
type: SpeciesReference
stoichiometry: 1.0
species: 168473

266525
type: SpeciesReference
stoichiometry: 1.0
species: 173497

266513
type: SpeciesReference
stoichiometry: 1.0
species: 167639

167639
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Carbamoyl phosphate_CH2NO5P

266598
type: SpeciesReference
stoichiometry: 1.0
species: 173497

266501
type: SpeciesReference
stoichiometry: 1.0
species: 183953

188346
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Xanthosine 5'-phosphate_C10H11N4O9P

179968
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (trimannosyl),(phosphoethanolaminyl)-mannosyl-glucosaminyl-acylphosphatidylinositol (M4C)_C57H104N2O37P2FULLRCO2FULLR2CO2

950618
type: Reaction
product: 238619
reactant: 238607
notes: R_It subsystem: Transport, Extracellular R_It equation: i[e] <==> i[c]
is: ENSMUSG00000020062.6
is: ENSMUSG00000000792.1
fast: false
reversible: true
name: Iodide uniport

238619
type: SpeciesReference
stoichiometry: 1.0
species: 177047

238607
type: SpeciesReference
stoichiometry: 1.0
species: 177059

946626
type: Reaction
product: 201963
product: 201951
reversible: true
product: 201939
reactant: 201902
is: http://identifiers.org/ec-code/1.1.1.35
reactant: 201854
reactant: 201890
fast: false
notes: R_HACD1m subsystem: Tryptophan metabolism R_HACD1m equation: [m] : aacoa + h + nadh <==> 3hbcoa + nad R_HACD9m subsystem: Valine, Leucine, and Isoleucine Metabolism R_HACD9m equation: [m] : 3hmbcoa + nad <==> 2maacoa + h + nadh
reactant: 201866
reactant: 201878
product: 201926
product: 201914
is: ENSMUSG00000025260.3

201963
type: SpeciesReference
stoichiometry: 1.0
species: 181522

201951
type: SpeciesReference
stoichiometry: 1.0
species: 175770

201939
type: SpeciesReference
stoichiometry: 1.0
species: 181461

201902
type: SpeciesReference
stoichiometry: 1.0
species: 181522

201854
type: SpeciesReference
stoichiometry: 1.0
species: 164378

201890
type: SpeciesReference
stoichiometry: 1.0
species: 175770

201866
type: SpeciesReference
stoichiometry: 1.0
species: 181461

201878
type: SpeciesReference
stoichiometry: 1.0
species: 161891

161891
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574

201926
type: SpeciesReference
stoichiometry: 1.0
species: 161417

161417
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574

201914
type: SpeciesReference
stoichiometry: 1.0
species: 161855

952267
type: Reaction
product: 254427
product: 254379
product: 254488
modifier: 254512
modifier: 254632
modifier: 254572
product: 254451
reactant: 254235
reactant: 254295
modifier: 254524
modifier: 254596
modifier: 254548
modifier: 254620
reactant: 254259
product: 254463
is: http://identifiers.org/ec-code/1.2.1.3
notes: R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD19x_LPAREN_P_RPAREN_ subsystem: Phenylalanine metabolism R_ALDD19x_LPAREN_P_RPAREN_ equation: [c] : h2o + nadp + pacald --> (2) h + nadph + pac R_3MOX4HOXPGALDOX subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX equation: [c] : 3m4hpga + h2o + nad --> 3mox4hoxm + (2) h + nadh R_MACOXO subsystem: Histidine Metabolism R_MACOXO equation: [c] : 3mldz + h2o + nad --> 3mlda + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_4HOXPACDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_4HOXPACDOX_LPAREN_NADP_RPAREN_ equation: [c] : 4hoxpacd + h2o + nadp <==> 4hphac + (2) h + nadph R_3M4HDXPAC subsystem: Tyrosine metabolism R_3M4HDXPAC equation: [c] : 3mox4hpac + h2o + nad <==> (2) h + homoval + nadh R_34DHPLACOX subsystem: Tyrosine metabolism R_34DHPLACOX equation: [c] : 34dhpac + h2o + nad --> 34dhpha + (2) h + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ equation: [c] : 3m4hpga + h2o + nadp <==> 3mox4hoxm + (2) h + nadph R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_ALDD19x subsystem: Phenylalanine metabolism R_ALDD19x equation: [c] : h2o + nad + pacald --> (2) h + nadh + pac R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh R_34DHXMANDACOX subsystem: Tyrosine metabolism R_34DHXMANDACOX equation: [c] : 34dhmald + h2o + nad --> 34dhoxmand + (2) h + nadh
modifier: 254608
modifier: 254536
reactant: 254319
modifier: 254500
reversible: false
reactant: 254199
reactant: 254211
product: 254439
product: 254415
product: 254367
modifier: 254560
reactant: 254223
product: 254391
reactant: 254283
product: 254403
product: 254355
is: ENSMUSG00000015134.7
product: 254476
reactant: 254331
modifier: 254584
reactant: 254187
product: 254343
is: http://identifiers.org/ec-code/1.2.1.21
fast: false
reactant: 254307
is: http://identifiers.org/ec-code/1.2.1.5
reactant: 254271
is: http://identifiers.org/ec-code/1.2.1.39
reactant: 254247

254427
type: SpeciesReference
stoichiometry: 1.0
species: 179086

254379
type: SpeciesReference
stoichiometry: 1.0
species: 161563

254488
type: SpeciesReference
stoichiometry: 10.0
species: 181510

254451
type: SpeciesReference
stoichiometry: 23.0
species: 175722

254235
type: SpeciesReference
stoichiometry: 1.0
species: 164534

254295
type: SpeciesReference
stoichiometry: 12.0
species: 175614

254259
type: SpeciesReference
stoichiometry: 1.0
species: 162011

254463
type: SpeciesReference
stoichiometry: 1.0
species: 162120

254319
type: SpeciesReference
stoichiometry: 1.0
species: 179122

254199
type: SpeciesReference
stoichiometry: 1.0
species: 179146

254211
type: SpeciesReference
stoichiometry: 10.0
species: 181437

254439
type: SpeciesReference
stoichiometry: 1.0
species: 179050

254415
type: SpeciesReference
stoichiometry: 2.0
species: 182816

254367
type: SpeciesReference
stoichiometry: 1.0
species: 174334

254223
type: SpeciesReference
stoichiometry: 1.0
species: 173947

254391
type: SpeciesReference
stoichiometry: 1.0
species: 161599

254283
type: SpeciesReference
stoichiometry: 2.0
species: 182827

254403
type: SpeciesReference
stoichiometry: 1.0
species: 162047

254355
type: SpeciesReference
stoichiometry: 1.0
species: 164438

254476
type: SpeciesReference
stoichiometry: 1.0
species: 181631

254331
type: SpeciesReference
stoichiometry: 1.0
species: 161551

254187
type: SpeciesReference
stoichiometry: 1.0
species: 162059

254343
type: SpeciesReference
stoichiometry: 1.0
species: 174805

254307
type: SpeciesReference
stoichiometry: 1.0
species: 174250

254271
type: SpeciesReference
stoichiometry: 1.0
species: 181558

254247
type: SpeciesReference
stoichiometry: 1.0
species: 161587

186573
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: tetracosapentaenoyl carnitine_C31H51NO4

169007
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 4_C31H49NO29S

954934
type: Reaction
name: monoacylglycerol acyltransferase
is: ENSMUSG00000052396.6
notes: R_MOGAT subsystem: Triacylglycerol Synthesis R_MOGAT equation: [c] : Rtotalcoa + mag_hs --> coa + dag_hs
is: ENSMUSG00000012187.5
reversible: false
reactant: 280421
reactant: 280409
product: 280433
fast: false
product: 280445

280421
type: SpeciesReference
stoichiometry: 1.0
species: 164174

164174
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: R total Coenzyme A_CO2FULLRC21H31N7O15P3S

280409
type: SpeciesReference
stoichiometry: 1.0
species: 180306

280433
type: SpeciesReference
stoichiometry: 1.0
species: 168509

280445
type: SpeciesReference
stoichiometry: 1.0
species: 169878

945703
type: Reaction
reactant: 193573
reactant: 193561
product: 193707
reactant: 193646
reversible: false
product: 193694
product: 193670
reactant: 193634
reactant: 193622
product: 193755
product: 193682
is: ENSMUSG00000022884.5
reactant: 193610
notes: R_HSD3B3r subsystem: Steroid Metabolism R_HSD3B3r equation: [r] : eandrstrn + h + nadph --> andrstandn + h2o + nadp R_HSD3B2r subsystem: Steroid Metabolism R_HSD3B2r equation: [r] : eandrstrn + h + nadh --> andrstandn + h2o + nad R_HSD3B11r subsystem: Steroid Metabolism R_HSD3B11r equation: [r] : nad + prgnlone --> h + nadh + prgstrn R_HSD3B12r subsystem: Steroid Metabolism R_HSD3B12r equation: [r] : dhea + nad --> andrstndn + h + nadh R_HSD3B13r subsystem: Steroid Metabolism R_HSD3B13r equation: [r] : 17ahprgnlone + nad --> 17ahprgstrn + h + nadh
product: 193743
product: 193731
product: 193658
reactant: 193597
reactant: 193585
is: ENSMUSG00000060782.5
product: 193719
fast: false

193573
type: SpeciesReference
stoichiometry: 1.0
species: 181667

193561
type: SpeciesReference
stoichiometry: 1.0
species: 184146

184146
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Pregnenolone_C21H32O2

193707
type: SpeciesReference
stoichiometry: 1.0
species: 181607

193646
type: SpeciesReference
stoichiometry: 2.0
species: 171920

193694
type: SpeciesReference
stoichiometry: 1.0
species: 166315

193670
type: SpeciesReference
stoichiometry: 2.0
species: 166303

193634
type: SpeciesReference
stoichiometry: 1.0
species: 181534

181534
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2

193622
type: SpeciesReference
stoichiometry: 2.0
species: 175794

193755
type: SpeciesReference
stoichiometry: 1.0
species: 161028

161028
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _17alpha-Hydroxyprogesterone_C21H30O3

193682
type: SpeciesReference
stoichiometry: 1.0
species: 184194

193610
type: SpeciesReference
stoichiometry: 1.0
species: 170749

170749
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Dehydroepiandrosterone_C19H28O2

193743
type: SpeciesReference
stoichiometry: 3.0
species: 181534

193731
type: SpeciesReference
stoichiometry: 3.0
species: 175794

193658
type: SpeciesReference
stoichiometry: 2.0
species: 175686

193597
type: SpeciesReference
stoichiometry: 3.0
species: 181486

181486
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2

193585
type: SpeciesReference
stoichiometry: 1.0
species: 161004

161004
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _17alpha-Hydroxypregnenolone_C21H32O3

193719
type: SpeciesReference
stoichiometry: 1.0
species: 181486

164426
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Acetyl-ACP_C13H23N2O8PRS

170374
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526

166591
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: arachidyl carnitine_C27H53NO4

164932
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (Gal)3 (Glc)1 (GlcNAc)3 (Cer)1_C66H115N4O37FULLRCO

952027
type: Reaction
product: 251863
product: 251851
reversible: false
fast: false
reactant: 251815
is: ENSMUSG00000030339.6
reactant: 251791
notes: R_AKR1D2 subsystem: Bile Acid Biosynthesis R_AKR1D2 equation: [c] : h + nadph + xoldiolone --> nadp + xoldioloneh R_AKR1D subsystem: Bile Acid Biosynthesis R_AKR1D equation: [c] : h + nadph + xol7aone --> nadp + xol7ah
product: 251839
reactant: 251827
reactant: 251803

251863
type: SpeciesReference
stoichiometry: 1.0
species: 188526

188526
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one_C27H46O3

251851
type: SpeciesReference
stoichiometry: 2.0
species: 181558

251815
type: SpeciesReference
stoichiometry: 2.0
species: 175722

251791
type: SpeciesReference
stoichiometry: 1.0
species: 188502

188502
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _7alpha,12alpha-Dihydroxycholest-4-en-3-one_C27H44O3

251839
type: SpeciesReference
stoichiometry: 1.0
species: 188466

188466
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _7alpha-Hydroxy-5beta-cholestan-3-one_C27H46O2

251827
type: SpeciesReference
stoichiometry: 2.0
species: 181631

251803
type: SpeciesReference
stoichiometry: 1.0
species: 188478

188478
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _7alpha-Hydroxycholest-4-en-3-one_C27H44O2

162580
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-4-Hydroxyglutamate semialdehyde_C5H9NO4

945999
type: Reaction
notes: R_PYNP2r subsystem: Pyrimidine Catabolism R_PYNP2r equation: [c] : pi + uri <==> r1p + ura
reactant: 196034
product: 196058
name: pyrimidine-nucleoside phosphorylase (uracil)
is: ENSMUSG00000020407.5
product: 196046
fast: false
reversible: true
reactant: 196022
is: http://identifiers.org/ec-code/2.4.2.2

196034
type: SpeciesReference
stoichiometry: 1.0
species: 188032

196058
type: SpeciesReference
stoichiometry: 1.0
species: 187948

196046
type: SpeciesReference
stoichiometry: 1.0
species: 184927

184927
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: alpha-D-Ribose 1-phosphate_C5H9O8P

196022
type: SpeciesReference
stoichiometry: 1.0
species: 183652

950558
type: Reaction
product: 238207
reactant: 238195
notes: R_DCIm subsystem: Fatty Acid Metabolism R_DCIm equation: [m] : dd2coa <==> dd3coa
is: ENSMUSG00000024132.4
is: http://identifiers.org/ec-code/5.3.3.8
fast: false
reversible: true
name: dodecenoyl-Coenzyme A delta isomerase

238207
type: SpeciesReference
stoichiometry: 1.0
species: 170266

170266
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3-dodecenoyl CoA_C33H52N7O17P3S

238195
type: SpeciesReference
stoichiometry: 1.0
species: 170254

170254
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: trans-Dodec-2-enoyl-CoA_C33H52N7O17P3S

175962
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Hexadecanoate (n-C16:0)_C16H31O2

176349
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Homoserine_C4H9NO3

946976
type: Reaction
product: 205268
reversible: false
product: 205318
reactant: 205232
notes: R_ACCOACm subsystem: Fatty Acid Metabolism R_ACCOACm equation: [m] : accoa + atp + hco3 --> adp + h + malcoa + pi R_ACCOAC subsystem: Fatty Acid Metabolism R_ACCOAC equation: [c] : accoa + atp + hco3 --> adp + h + malcoa + pi
reactant: 205208
product: 205330
product: 205281
reactant: 205196
is: ENSMUSG00000026944.9
reactant: 205171
reactant: 205183
product: 205305
product: 205293
fast: false
is: http://identifiers.org/ec-code/6.4.1.2
product: 205256
product: 205244
reactant: 205220

205268
type: SpeciesReference
stoichiometry: 1.0
species: 183700

205318
type: SpeciesReference
stoichiometry: 1.0
species: 175722

205232
type: SpeciesReference
stoichiometry: 1.0
species: 164583

205208
type: SpeciesReference
stoichiometry: 1.0
species: 164607

205330
type: SpeciesReference
stoichiometry: 1.0
species: 175770

205281
type: SpeciesReference
stoichiometry: 1.0
species: 165411

205196
type: SpeciesReference
stoichiometry: 1.0
species: 166904

205171
type: SpeciesReference
stoichiometry: 1.0
species: 175902

205183
type: SpeciesReference
stoichiometry: 1.0
species: 175878

205305
type: SpeciesReference
stoichiometry: 1.0
species: 165387

205293
type: SpeciesReference
stoichiometry: 1.0
species: 180379

205256
type: SpeciesReference
stoichiometry: 1.0
species: 183652

205244
type: SpeciesReference
stoichiometry: 1.0
species: 180391

205220
type: SpeciesReference
stoichiometry: 1.0
species: 166928

170858
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Dihydrolipolprotein_H2S2X

168328
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: CMP_C9H12N3O8P

945294
type: Reaction
fast: false
product: 190423
name: ADPribose diphosphatase (mitochondrial)
is: ENSMUSG00000029310.6
is: http://identifiers.org/ec-code/3.6.1.13
product: 190410
reactant: 190398
product: 190435
reactant: 190386
reversible: false
notes: R_ADPRDPm subsystem: Nucleotides R_ADPRDPm equation: [m] : adprib + h2o --> amp + (2) h + r5p

190423
type: SpeciesReference
stoichiometry: 1.0
species: 184951

184951
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: alpha-D-Ribose 5-phosphate_C5H9O8P

190410
type: SpeciesReference
stoichiometry: 1.0
species: 166267

190398
type: SpeciesReference
stoichiometry: 1.0
species: 165521

165521
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: ADPribose_C15H21N5O14P2

190435
type: SpeciesReference
stoichiometry: 2.0
species: 175770

190386
type: SpeciesReference
stoichiometry: 1.0
species: 175662

171111
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N,N-Dimethylglycine_C4H9NO2

952195
type: Reaction
product: 253644
reactant: 253462
reactant: 253510
product: 253694
reactant: 253535
product: 253707
fast: false
product: 253657
reversible: false
is: ENSMUSG00000026170.5
product: 253733
product: 253682
product: 253632
product: 253620
product: 253584
product: 253608
reactant: 253498
reactant: 253571
is: http://identifiers.org/ec-code/1.14.13.15
reactant: 253438
notes: R_P45027A11m subsystem: Bile Acid Biosynthesis R_P45027A11m equation: [m] : h + nadph + o2 + xoltriol --> h2o + nadp + xoltetrol R_P45027A16m subsystem: Bile Acid Biosynthesis R_P45027A16m equation: [m] : nadph + o2 + xol7ah2al --> dhcholestanate + h2o + nadp R_VITD3Hm subsystem: Vitamin D R_VITD3Hm equation: [m] : h + nadph + o2 + vitd3 --> 25hvitd3 + h2o + nadp R_P45027A14m subsystem: Bile Acid Biosynthesis R_P45027A14m equation: [m] : h + nadph + o2 + xol7ah2 --> h2o + nadp + xol7ah3 R_P45027A15m subsystem: Bile Acid Biosynthesis R_P45027A15m equation: [m] : h + nadph + o2 + xol7ah3 --> (2) h2o + nadp + xol7ah2al R_P45027A13m subsystem: Bile Acid Biosynthesis R_P45027A13m equation: [m] : nadph + o2 + thcholst --> h2o + nadp + thcholstoic R_P45027A1m subsystem: Bile Acid Biosynthesis R_P45027A1m equation: [m] : chsterol + h + nadph + o2 --> h2o + nadp + xol27oh R_VITD2Hm subsystem: Vitamin D R_VITD2Hm equation: [m] : h + nadph + o2 + vitd2 --> 25hvitd2 + h2o + nadp R_P45027A12m subsystem: Bile Acid Biosynthesis R_P45027A12m equation: [m] : nadp + xoltetrol --> h + nadph + thcholst
reactant: 253450
reactant: 253559
reactant: 253486
product: 253596
reactant: 253426
reactant: 253547
product: 253669
reactant: 253474
product: 253720
reactant: 253522

253644
type: SpeciesReference
stoichiometry: 1.0
species: 170616

170616
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3alpha,7alpha-Dihydroxy-5beta-cholestanate_C27H45O4

253462
type: SpeciesReference
stoichiometry: 1.0
species: 188237

188237
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Vitamin D2_C28H44O

253510
type: SpeciesReference
stoichiometry: 1.0
species: 188430

188430
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3alpha,7alpha-Dihydroxy-5beta-cholestane_C27H48O2

253694
type: SpeciesReference
stoichiometry: 1.0
species: 161234

253535
type: SpeciesReference
stoichiometry: 1.0
species: 188249

253707
type: SpeciesReference
stoichiometry: 8.0
species: 181583

253657
type: SpeciesReference
stoichiometry: 1.0
species: 188382

188382
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _27-Hydroxycholesterol_C27H46O2

253733
type: SpeciesReference
stoichiometry: 1.0
species: 175770

253682
type: SpeciesReference
stoichiometry: 1.0
species: 188454

188454
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3alpha,7alpha,26-Trihydroxy-5beta-cholestane_C27H48O3

253632
type: SpeciesReference
stoichiometry: 1.0
species: 161222

253620
type: SpeciesReference
stoichiometry: 9.0
species: 175662

253584
type: SpeciesReference
stoichiometry: 1.0
species: 188442

253608
type: SpeciesReference
stoichiometry: 1.0
species: 186730

186730
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate_C27H45O5

253498
type: SpeciesReference
stoichiometry: 1.0
species: 188454

253571
type: SpeciesReference
stoichiometry: 6.0
species: 175770

253438
type: SpeciesReference
stoichiometry: 1.0
species: 186718

186718
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al_C27H46O4

253450
type: SpeciesReference
stoichiometry: 1.0
species: 168064

168064
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Cholesterol_C27H46O

253559
type: SpeciesReference
stoichiometry: 8.0
species: 182178

253486
type: SpeciesReference
stoichiometry: 1.0
species: 188574

188574
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane_C27H48O4

253596
type: SpeciesReference
stoichiometry: 1.0
species: 186718

253426
type: SpeciesReference
stoichiometry: 1.0
species: 188442

253547
type: SpeciesReference
stoichiometry: 8.0
species: 181643

253669
type: SpeciesReference
stoichiometry: 1.0
species: 188574

253474
type: SpeciesReference
stoichiometry: 1.0
species: 188634

188634
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane_C27H48O3

253720
type: SpeciesReference
stoichiometry: 1.0
species: 181643

253522
type: SpeciesReference
stoichiometry: 1.0
species: 181583

161818
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598

950834
type: Reaction
reactant: 241148
is: ENSMUSG00000063779.4
is: ENSMUSG00000062778.5
is: http://identifiers.org/ec-code/3.2.1.14
notes: R_CHTNASEe subsystem: Aminosugar Metabolism R_CHTNASEe equation: [e] : chtn + (2) h2o --> (3) acgam R_CHTNASE subsystem: Aminosugar Metabolism R_CHTNASE equation: [c] : chtn + (2) h2o --> (3) acgam
reactant: 241112
product: 241160
reactant: 241124
fast: false
product: 241172
reversible: false
is: ENSMUSG00000043873.3
reactant: 241136
is: ENSMUSG00000040809.7

241148
type: SpeciesReference
stoichiometry: 1.0
species: 168124

168124
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: chitin_C24H41N3O16

241112
type: SpeciesReference
stoichiometry: 1.0
species: 168112

168112
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: chitin_C24H41N3O16

241160
type: SpeciesReference
stoichiometry: 3.0
species: 164860

164860
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Acetyl-D-glucosamine_C8H15NO6

241124
type: SpeciesReference
stoichiometry: 2.0
species: 175626

241172
type: SpeciesReference
stoichiometry: 3.0
species: 164872

241136
type: SpeciesReference
stoichiometry: 2.0
species: 175614

180270
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (alpha-D-Mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1725H2840N20O620P20

184290
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: D-Proline_C5H9NO2

949464
type: Reaction
fast: false
reactant: 227251
reactant: 227239
is: ENSMUSG00000033122.6
is: http://identifiers.org/ec-code/1.1.1.62
product: 227276
reactant: 227264
product: 227288
notes: R_HSD17B3r subsystem: Steroid Metabolism R_HSD17B3r equation: [r] : andrstndn + h + nadph --> nadp + tststerone
reversible: false
name: testicular 17-beta-hydroxysteroid dehydrogenase

227251
type: SpeciesReference
stoichiometry: 1.0
species: 166315

227239
type: SpeciesReference
stoichiometry: 1.0
species: 181667

227276
type: SpeciesReference
stoichiometry: 1.0
species: 187332

227264
type: SpeciesReference
stoichiometry: 1.0
species: 175794

227288
type: SpeciesReference
stoichiometry: 1.0
species: 181607

166820
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Asparagine_C4H8N2O3

175250
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Guanosine_C10H13N5O5

187839
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: UDP-D-xylose_C14H20N2O16P2

948094
type: Reaction
product: 214416
product: 214428
reactant: 214392
name: phospholipase
notes: R_LPS4e subsystem: Triacylglycerol Synthesis R_LPS4e equation: [e] : h2o + pglyc_hs --> 1glyc_hs + Rtotal2 + h
product: 214440
fast: false
reactant: 214404
is: ENSMUSG00000034579.8
reversible: false

214416
type: SpeciesReference
stoichiometry: 1.0
species: 175734

214428
type: SpeciesReference
stoichiometry: 1.0
species: 161076

161076
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: _1 acyl phosphoglycerol_C6H13O7PFULLRCO2

214392
type: SpeciesReference
stoichiometry: 1.0
species: 183459

183459
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: phosphatidylglycerol (homo sapiens)_C6H12O6PFULLRCO2FULLR2CO2

214440
type: SpeciesReference
stoichiometry: 1.0
species: 163992

214404
type: SpeciesReference
stoichiometry: 1.0
species: 175626

182575
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: octadecenoyl carnitine_C25H47NO4

953553
type: Reaction
fast: false
is: http://identifiers.org/ec-code/1.11.1.9
is: ENSMUSG00000005161.7
product: 267942
reactant: 267930
name: glutathione peridoxase
product: 267954
notes: R_GTHP subsystem: Glutathione Metabolism R_GTHP equation: [c] : (2) gthrd + h2o2 <==> gthox + (2) h2o
reactant: 267918
is: ENSMUSG00000028691.5
reversible: true

267942
type: SpeciesReference
stoichiometry: 1.0
species: 175349

175349
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Oxidized glutathione_C20H30N6O12S2

267930
type: SpeciesReference
stoichiometry: 2.0
species: 175385

267954
type: SpeciesReference
stoichiometry: 2.0
species: 175614

267918
type: SpeciesReference
stoichiometry: 1.0
species: 175542

164318
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Tn antigen_C8H14NO5X

177760
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 23_C124H201N8O106S5

174926
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: GM1alpha (homo sapiens)_C55H95N3O30FULLRCO

951076
type: Reaction
is: ENSMUSG00000031352.2
reactant: 243525
product: 243549
fast: false
notes: R_NNMT subsystem: NAD Metabolism R_NNMT equation: [c] : amet + ncam --> 1mncam + ahcys
reactant: 243513
name: Nicotinamide N-methyltransferase
reversible: false
product: 243537
is: http://identifiers.org/ec-code/2.1.1.1

243525
type: SpeciesReference
stoichiometry: 1.0
species: 181716

181716
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Nicotinamide_C6H6N2O

243549
type: SpeciesReference
stoichiometry: 1.0
species: 161088

161088
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1-Methylnicotinamide_C7H9N2O

243513
type: SpeciesReference
stoichiometry: 1.0
species: 166159

243537
type: SpeciesReference
stoichiometry: 1.0
species: 165737

178762
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 6_C61H98N5O46SX

955861
type: Reaction
fast: false
product: 291471
name: uroporphyrinogen-III synthase
is: ENSMUSG00000030979.5
notes: R_UPP3S subsystem: Heme Biosynthesis R_UPP3S equation: [c] : hmbil --> h2o + uppg3
is: http://identifiers.org/ec-code/4.2.1.75
reactant: 291459
reversible: false
product: 291483

291471
type: SpeciesReference
stoichiometry: 1.0
species: 187936

187936
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Uroporphyrinogen III_C40H36N4O16

291459
type: SpeciesReference
stoichiometry: 1.0
species: 176265

291483
type: SpeciesReference
stoichiometry: 1.0
species: 175614

947144
type: Reaction
product: 206885
reactant: 206813
name: CTP synthase (glutamine)
is: http://identifiers.org/ec-code/6.3.4.2
is: ENSMUSG00000031360.6
product: 206897
product: 206873
reactant: 206825
notes: R_CTPS2 subsystem: Pyrimidine Biosynthesis R_CTPS2 equation: [c] : atp + gln-L + h2o + utp --> adp + ctp + glu-L + (2) h + pi
reactant: 206837
product: 206909
reactant: 206849
reversible: false
product: 206861
fast: false

206885
type: SpeciesReference
stoichiometry: 1.0
species: 165387

206813
type: SpeciesReference
stoichiometry: 1.0
species: 174382

206897
type: SpeciesReference
stoichiometry: 2.0
species: 175722

206873
type: SpeciesReference
stoichiometry: 1.0
species: 174442

206825
type: SpeciesReference
stoichiometry: 1.0
species: 166904

206837
type: SpeciesReference
stoichiometry: 1.0
species: 175614

206909
type: SpeciesReference
stoichiometry: 1.0
species: 169615

206849
type: SpeciesReference
stoichiometry: 1.0
species: 188092

206861
type: SpeciesReference
stoichiometry: 1.0
species: 183652

171379
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Dolichyl phosphate D-mannose, human uterine homolog_C1085H1780O90P10

188538
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: cholesterol ester (from FULLR2)_C27H45FULLR2CO2

165374
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Adenosylcobalamin_C72H100CoN18O17P

166483
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _20alpha-Hydroxyprogesterone_C21H32O2

164824
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Type IA glycolipid_C58H102N3O31FULLRCO

171099
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: demethylated antipyrine_C10H10N2O

162472
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: _4-Aminobutanoate_C4H9NO2

955969
type: Reaction
reactant: 292123
reactant: 292039
reactant: 292015
product: 292183
product: 292231
reversible: false
reactant: 292111
reactant: 292099
product: 292195
reactant: 292027
reactant: 292003
is: ENSMUSG00000029813.5
reactant: 292051
product: 292135
notes: R_PTRCOX1 subsystem: Arginine and Proline Metabolism R_PTRCOX1 equation: [c] : h2o + o2 + ptrc --> 4abutn + h2o2 + nh4 R_42A12BOOX subsystem: Tyrosine metabolism R_42A12BOOX equation: [c] : dopa + h2o + o2 --> 34dhpac + h2o2 + nh4 R_NMPTRCOX subsystem: Alkaloid biosynthesis II R_NMPTRCOX equation: [c] : nmptrc + o2 --> 1mpyr + h2o2 + nh4 R_MHISOR subsystem: Histidine Metabolism R_MHISOR equation: [c] : h2o + mhista + o2 --> 3mldz + h2o2 + nh4 R_PEAMNO subsystem: Phenylalanine metabolism R_PEAMNO equation: [c] : h2o + o2 + peamn --> h2o2 + nh4 + pacald R_TRYPTAOX subsystem: Tryptophan metabolism R_TRYPTAOX equation: [c] : h2o + o2 + trypta --> h2o2 + id3acald + nh4 R_HISTASE subsystem: Histidine Metabolism R_HISTASE equation: [c] : h2o + hista + o2 --> h2o2 + im4act + nh4 R_MAOX subsystem: Tyrosine metabolism R_MAOX equation: [c] : h2o + mma + o2 --> fald + h2o2 + nh4 R_13DAMPPOX subsystem: beta-Alanine metabolism R_13DAMPPOX equation: [c] : 13dampp + h2o + o2 --> bamppald + h2o2 + nh4
reactant: 292087
reactant: 292063
product: 292207
product: 292147
is: http://identifiers.org/ec-code/1.4.3.6
is: ENSMUSG00000068536.2
product: 292243
product: 292219
product: 292159
fast: false
product: 292255
is: http://identifiers.org/ec-code/1.4.3.4
reactant: 292075
is: ENSMUSG00000029811.6
product: 292171
is: ENSMUSG00000039215.3

292123
type: SpeciesReference
stoichiometry: 9.0
species: 182154

292039
type: SpeciesReference
stoichiometry: 1.0
species: 183349

292015
type: SpeciesReference
stoichiometry: 1.0
species: 187308

292183
type: SpeciesReference
stoichiometry: 1.0
species: 161587

292231
type: SpeciesReference
stoichiometry: 9.0
species: 175542

292111
type: SpeciesReference
stoichiometry: 1.0
species: 160956

292099
type: SpeciesReference
stoichiometry: 1.0
species: 184699

292195
type: SpeciesReference
stoichiometry: 1.0
species: 167001

292027
type: SpeciesReference
stoichiometry: 1.0
species: 181078

292003
type: SpeciesReference
stoichiometry: 1.0
species: 180824

292051
type: SpeciesReference
stoichiometry: 1.0
species: 181946

292135
type: SpeciesReference
stoichiometry: 1.0
species: 162059

292087
type: SpeciesReference
stoichiometry: 8.0
species: 175614

292063
type: SpeciesReference
stoichiometry: 1.0
species: 176241

292207
type: SpeciesReference
stoichiometry: 9.0
species: 181752

292147
type: SpeciesReference
stoichiometry: 1.0
species: 162496

292243
type: SpeciesReference
stoichiometry: 1.0
species: 177119

292219
type: SpeciesReference
stoichiometry: 1.0
species: 182827

292159
type: SpeciesReference
stoichiometry: 1.0
species: 177277

292255
type: SpeciesReference
stoichiometry: 1.0
species: 172584

292075
type: SpeciesReference
stoichiometry: 1.0
species: 171451

292171
type: SpeciesReference
stoichiometry: 1.0
species: 161100

954045
type: Reaction
reactant: 273467
notes: R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h R_PDE4n subsystem: Nucleotides R_PDE4n equation: [n] : 35cgmp + h2o --> gmp + h
product: 273518
reactant: 273479
product: 273531
reactant: 273455
is: ENSMUSG00000041119.4
product: 273492
product: 273505
is: http://identifiers.org/ec-code/3.1.4.17
reversible: false
fast: false
reactant: 273443

273467
type: SpeciesReference
stoichiometry: 1.0
species: 175674

273518
type: SpeciesReference
stoichiometry: 1.0
species: 175034

175034
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: GMP_C10H12N5O8P

273479
type: SpeciesReference
stoichiometry: 1.0
species: 161697

161697
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: _3',5'-Cyclic GMP_C10H11N5O7P

273531
type: SpeciesReference
stoichiometry: 1.0
species: 175722

273455
type: SpeciesReference
stoichiometry: 1.0
species: 175614

273492
type: SpeciesReference
stoichiometry: 1.0
species: 174986

273505
type: SpeciesReference
stoichiometry: 1.0
species: 175782

273443
type: SpeciesReference
stoichiometry: 1.0
species: 161660

167519
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: cAMP_C10H11N5O6P

953313
type: Reaction
product: 265992
reversible: false
is: http://identifiers.org/ec-code/2.6.1.3
modifier: 266138
modifier: 266126
modifier: 266114
is: http://identifiers.org/ec-code/2.6.1.1
is: http://identifiers.org/ec-code/2.6.1.58
modifier: 266162
product: 265980
fast: false
modifier: 266078
reactant: 265932
modifier: 266054
product: 266017
modifier: 266150
modifier: 266090
modifier: 266066
modifier: 266042
reactant: 265920
modifier: 266030
modifier: 266102
product: 266004
is: http://identifiers.org/ec-code/2.6.1.5
reactant: 265956
notes: R_EHGLAT2m subsystem: Arginine and Proline Metabolism R_EHGLAT2m equation: [m] : e4hglu + oaa --> 4h2oglt + asp-L R_TYRTAm subsystem: Tyrosine metabolism R_TYRTAm equation: [m] : akg + tyr-L <==> 34hpp + glu-L R_PHETA1m subsystem: Phenylalanine metabolism R_PHETA1m equation: [m] : akg + phe-L <==> glu-L + phpyr R_LCYSTATm subsystem: Cysteine Metabolism R_LCYSTATm equation: [m] : Lcyst + akg <==> 3spyr + glu-L R_CYSTAm subsystem: Cysteine Metabolism R_CYSTAm equation: [m] : akg + cys-L <==> glu-L + mercppyr R_ASPTAm subsystem: Alanine and Aspartate Metabolism R_ASPTAm equation: [m] : akg + asp-L <==> glu-L + oaa R_EHGLATm subsystem: Arginine and Proline Metabolism R_EHGLATm equation: [m] : akg + e4hglu --> 4h2oglt + glu-L R_3SALATAim subsystem: Cysteine Metabolism R_3SALATAim equation: [m] : 3sala + akg + h --> 3snpyr + glu-L
reactant: 265968
reactant: 265944
is: ENSMUSG00000031672.6
is: http://identifiers.org/ec-code/2.6.1.21

265992
type: SpeciesReference
stoichiometry: 2.0
species: 162544

162544
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _4-Hydroxy-2-oxoglutarate_C5H4O6

166892
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Aspartate_C4H6NO4

180704
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Mercaptopyruvate_C3H3O3S

187548
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Tyrosine_C9H11NO3

265980
type: SpeciesReference
stoichiometry: 2.0
species: 174478

183580
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Phenylpyruvate_C9H7O3

265932
type: SpeciesReference
stoichiometry: 1.0
species: 162278

162278
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3-Sulfino-L-alanine_C3H5NO4S

183508
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Phenylalanine_C9H11NO2

266017
type: SpeciesReference
stoichiometry: 1.0
species: 166892

169706
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Cysteine_C3H7NO2S

163787
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Cysteate_C3H6NO5S

265920
type: SpeciesReference
stoichiometry: 1.0
species: 182298

162326
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3-Sulfopyruvate_C3H2O6S

266004
type: SpeciesReference
stoichiometry: 1.0
species: 162302

162302
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: _3-Sulfinopyruvate_C3H2O5S

265956
type: SpeciesReference
stoichiometry: 2.0
species: 165895

265968
type: SpeciesReference
stoichiometry: 1.0
species: 175770

265944
type: SpeciesReference
stoichiometry: 2.0
species: 171884

948911
type: Reaction
product: 221450
is: ENSMUSG00000021919.5
reactant: 221402
fast: false
reactant: 221426
reversible: true
product: 221486
reactant: 221438
product: 221474
notes: R_CHAT subsystem: Glycerophospholipid Metabolism R_CHAT equation: [c] : accoa + chol <==> ach + coa R_CHATn subsystem: Glycerophospholipid Metabolism R_CHATn equation: [n] : accoa + chol <==> ach + coa
product: 221462
reactant: 221414

221450
type: SpeciesReference
stoichiometry: 1.0
species: 168557

221402
type: SpeciesReference
stoichiometry: 1.0
species: 167845

167845
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Choline_C5H14NO

221426
type: SpeciesReference
stoichiometry: 1.0
species: 167796

221486
type: SpeciesReference
stoichiometry: 1.0
species: 164992

164992
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Acetylcholine_C7H16NO2

221438
type: SpeciesReference
stoichiometry: 1.0
species: 164583

221474
type: SpeciesReference
stoichiometry: 1.0
species: 165016

165016
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Acetylcholine_C7H16NO2

221462
type: SpeciesReference
stoichiometry: 1.0
species: 168509

221414
type: SpeciesReference
stoichiometry: 1.0
species: 164619

164619
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Acetyl-CoA_C23H34N7O17P3S

167182
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Biliverdin_C33H32N4O6

951027
type: Reaction
product: 243175
product: 243272
reactant: 243019
product: 243187
product: 243285
product: 243297
reactant: 242982
product: 243309
reactant: 242970
reactant: 242958
is: http://identifiers.org/ec-code/1.2.1.47
reactant: 243079
is: http://identifiers.org/ec-code/1.2.1.4
product: 243151
notes: R_BETALDHx subsystem: Glycine, Serine, and Threonine Metabolism R_BETALDHx equation: [c] : betald + h2o + nad --> glyb + (2) h + nadh R_ALDD2y subsystem: Glycolysis/Gluconeogenesis R_ALDD2y equation: [c] : acald + h2o + nadp --> ac + (2) h + nadph R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD20x subsystem: Tryptophan metabolism R_ALDD20x equation: [c] : h2o + id3acald + nad --> (2) h + ind3ac + nadh R_BAMPPALDOX subsystem: beta-Alanine metabolism R_BAMPPALDOX equation: [c] : bamppald + h2o + nad --> ala-B + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_IMACTD subsystem: Histidine Metabolism R_IMACTD equation: [c] : h2o + im4act + nad --> (2) h + im4ac + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_PYLALDOX subsystem: Limonene and pinene degradation R_PYLALDOX equation: [c] : h2o + nad + pylald --> (2) h + nadh + peracd R_NABTNO subsystem: Arginine and Proline Metabolism R_NABTNO equation: [c] : h2o + n4abutn + nad --> 4aabutn + (2) h + nadh R_ABUTD subsystem: beta-Alanine metabolism R_ABUTD equation: [c] : 4abutn + h2o + nad --> 4abut + (2) h + nadh R_5HOXINDACTOX subsystem: Tryptophan metabolism R_5HOXINDACTOX equation: [c] : 5hoxindact + h2o + nad --> 5hoxindoa + (2) h + nadh R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_TMABADH subsystem: Lysine Metabolism R_TMABADH equation: [c] : 4tmeabut + h2o + nad --> 4tmeabutn + (2) h + nadh R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh
reactant: 243031
product: 243163
product: 243247
product: 243260
reactant: 243091
is: ENSMUSG00000026687.8
is: http://identifiers.org/ec-code/1.2.1.21
reactant: 242934
is: http://identifiers.org/ec-code/1.2.1.19
reactant: 243055
reactant: 243007
fast: false
reactant: 242922
product: 243223
product: 243235
product: 243139
reactant: 243067
reactant: 243103
is: http://identifiers.org/ec-code/1.2.1.8
reversible: false
reactant: 242995
product: 243211
reactant: 243115
product: 243199
reactant: 243043
product: 243321
product: 243127
reactant: 242946
is: http://identifiers.org/ec-code/1.2.1.3

243175
type: SpeciesReference
stoichiometry: 2.0
species: 164438

243272
type: SpeciesReference
stoichiometry: 1.0
species: 165931

243019
type: SpeciesReference
stoichiometry: 2.0
species: 164534

243187
type: SpeciesReference
stoichiometry: 1.0
species: 162422

243285
type: SpeciesReference
stoichiometry: 1.0
species: 179050

243297
type: SpeciesReference
stoichiometry: 31.0
species: 175722

242982
type: SpeciesReference
stoichiometry: 14.0
species: 181437

243309
type: SpeciesReference
stoichiometry: 1.0
species: 181631

242970
type: SpeciesReference
stoichiometry: 1.0
species: 184795

242958
type: SpeciesReference
stoichiometry: 1.0
species: 177277

243079
type: SpeciesReference
stoichiometry: 1.0
species: 177119

243151
type: SpeciesReference
stoichiometry: 1.0
species: 162446

243031
type: SpeciesReference
stoichiometry: 1.0
species: 167001

243163
type: SpeciesReference
stoichiometry: 1.0
species: 177325

243247
type: SpeciesReference
stoichiometry: 1.0
species: 183410

243260
type: SpeciesReference
stoichiometry: 1.0
species: 162835

243091
type: SpeciesReference
stoichiometry: 16.0
species: 175614

242934
type: SpeciesReference
stoichiometry: 1.0
species: 181340

243055
type: SpeciesReference
stoichiometry: 1.0
species: 163136

243007
type: SpeciesReference
stoichiometry: 1.0
species: 162811

162811
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _4-Trimethylammoniobutanal_C7H16NO

242922
type: SpeciesReference
stoichiometry: 1.0
species: 179146

243223
type: SpeciesReference
stoichiometry: 1.0
species: 174697

174697
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Glycine betaine_C5H11NO2

243235
type: SpeciesReference
stoichiometry: 1.0
species: 179086

243139
type: SpeciesReference
stoichiometry: 1.0
species: 174805

243067
type: SpeciesReference
stoichiometry: 1.0
species: 181558

243103
type: SpeciesReference
stoichiometry: 1.0
species: 174250

242995
type: SpeciesReference
stoichiometry: 1.0
species: 173947

243211
type: SpeciesReference
stoichiometry: 1.0
species: 163161

243115
type: SpeciesReference
stoichiometry: 1.0
species: 179122

243199
type: SpeciesReference
stoichiometry: 1.0
species: 174334

243043
type: SpeciesReference
stoichiometry: 1.0
species: 167037

167037
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Betaine aldehyde_C5H12NO

243321
type: SpeciesReference
stoichiometry: 14.0
species: 181510

243127
type: SpeciesReference
stoichiometry: 1.0
species: 177253

242946
type: SpeciesReference
stoichiometry: 1.0
species: 162496

949500
type: Reaction
reactant: 227446
product: 227471
reversible: true
reactant: 227434
notes: R_THD1m subsystem: NAD Metabolism R_THD1m equation: h[c] + nadh[m] + nadp[m] <==> h[m] + nad[m] + nadph[m]
is: ENSMUSG00000025453.7
product: 227483
is: http://identifiers.org/ec-code/1.6.1.1
reactant: 227458
fast: false
name: NAD(P) transhydrogenase
product: 227495

227446
type: SpeciesReference
stoichiometry: 1.0
species: 175722

227471
type: SpeciesReference
stoichiometry: 1.0
species: 181461

227434
type: SpeciesReference
stoichiometry: 1.0
species: 181583

227483
type: SpeciesReference
stoichiometry: 1.0
species: 181643

227458
type: SpeciesReference
stoichiometry: 1.0
species: 181522

227495
type: SpeciesReference
stoichiometry: 1.0
species: 175770

161112
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: _1-Pyrroline-2-carboxylate_C5H6NO2

185373
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Se-Adenosylselenohomocysteine_C14H20N6O5Se

178666
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II (core 2-linked)_C81H129N6O67S3X

172017
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Eicosatetranoyl carnitine_C27H45NO4

948851
type: Reaction
product: 220920
product: 220884
reversible: false
reactant: 220740
reactant: 220824
product: 220944
product: 220872
reactant: 220764
reactant: 220776
product: 220956
product: 220896
product: 220848
fast: false
reactant: 220704
reactant: 220692
notes: R_LEUt4 subsystem: Transport, Extracellular R_LEUt4 equation: leu-L[e] + na1[e] --> leu-L[c] + na1[c] R_SERt4 subsystem: Transport, Extracellular R_SERt4 equation: na1[e] + ser-L[e] --> na1[c] + ser-L[c] R_ALAt4 subsystem: Transport, Extracellular R_ALAt4 equation: ala-L[e] + na1[e] --> ala-L[c] + na1[c] R_PROt4 subsystem: Transport, Extracellular R_PROt4 equation: na1[e] + pro-L[e] --> na1[c] + pro-L[c] R_ASNt4 subsystem: Transport, Extracellular R_ASNt4 equation: asn-L[e] + na1[e] --> asn-L[c] + na1[c] R_ARGtiDF subsystem: Transport, Extracellular R_ARGtiDF equation: arg-L[e] --> arg-L[c] R_LYStiDF subsystem: Transport, Extracellular R_LYStiDF equation: lys-L[e] --> lys-L[c] R_HIStiDF subsystem: Transport, Extracellular R_HIStiDF equation: his-L[e] --> his-L[c] R_GLYt4 subsystem: Transport, Extracellular R_GLYt4 equation: gly[e] + na1[e] --> gly[c] + na1[c] R_PHEt4 subsystem: Transport, Extracellular R_PHEt4 equation: na1[e] + phe-L[e] --> na1[c] + phe-L[c] R_GLNt4 subsystem: Transport, Extracellular R_GLNt4 equation: gln-L[e] + na1[e] --> gln-L[c] + na1[c]
product: 220836
reactant: 220812
reactant: 220728
is: ENSMUSG00000022464.5
product: 220968
reactant: 220752
product: 220908
reactant: 220788
product: 220932
product: 220860
reactant: 220800
reactant: 220716

220920
type: SpeciesReference
stoichiometry: 1.0
species: 166796

220884
type: SpeciesReference
stoichiometry: 1.0
species: 176216

220740
type: SpeciesReference
stoichiometry: 8.0
species: 181389

220824
type: SpeciesReference
stoichiometry: 1.0
species: 183496

220944
type: SpeciesReference
stoichiometry: 1.0
species: 166015

220872
type: SpeciesReference
stoichiometry: 1.0
species: 174382

220764
type: SpeciesReference
stoichiometry: 1.0
species: 166736

220776
type: SpeciesReference
stoichiometry: 1.0
species: 174637

220956
type: SpeciesReference
stoichiometry: 1.0
species: 183483

220896
type: SpeciesReference
stoichiometry: 8.0
species: 181377

220848
type: SpeciesReference
stoichiometry: 1.0
species: 174625

220704
type: SpeciesReference
stoichiometry: 1.0
species: 179243

179243
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: L-Leucine_C6H13NO2

220692
type: SpeciesReference
stoichiometry: 1.0
species: 176228

220836
type: SpeciesReference
stoichiometry: 1.0
species: 179847

220812
type: SpeciesReference
stoichiometry: 1.0
species: 185544

220728
type: SpeciesReference
stoichiometry: 1.0
species: 166808

220968
type: SpeciesReference
stoichiometry: 1.0
species: 184326

220752
type: SpeciesReference
stoichiometry: 1.0
species: 184338

220908
type: SpeciesReference
stoichiometry: 1.0
species: 166724

220788
type: SpeciesReference
stoichiometry: 1.0
species: 179859

220932
type: SpeciesReference
stoichiometry: 1.0
species: 179231

220860
type: SpeciesReference
stoichiometry: 1.0
species: 185532

220800
type: SpeciesReference
stoichiometry: 1.0
species: 174394

220716
type: SpeciesReference
stoichiometry: 1.0
species: 166027

184182
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Progesterone_C21H30O2

185411
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Selenate_O4Se

945355
type: Reaction
is: http://identifiers.org/ec-code/1.1.1.105
product: 190869
product: 190881
fast: false
product: 190857
reactant: 190832
name: retinol dehydrogenase (all-trans,NADPH)
reversible: true
is: ENSMUSG00000025921.6
reactant: 190845
is: ENSMUSG00000028236.2
notes: R_RDH1a subsystem: Vitamin A Metabolism R_RDH1a equation: [c] : nadp + retinol <==> h + nadph + retinal

190869
type: SpeciesReference
stoichiometry: 1.0
species: 185011

190881
type: SpeciesReference
stoichiometry: 1.0
species: 181631

190857
type: SpeciesReference
stoichiometry: 1.0
species: 175722

190832
type: SpeciesReference
stoichiometry: 1.0
species: 185060

190845
type: SpeciesReference
stoichiometry: 1.0
species: 181558

166712
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: D-Arginine_C6H15N4O2

178075
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 9_C188H301N13O166S10

182467
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Octadecynoyl-ACP (n-C18:2ACP)_C29H51N2O8PRS

163859
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Acetyl-L-aspartate_C6H7NO5

949091
type: Reaction
is: ENSMUSG00000038526.7
reversible: true
is: http://identifiers.org/ec-code/4.2.1.1
is: ENSMUSG00000027555.7
notes: R_H2CO3D subsystem: Miscellaneous R_H2CO3D equation: [c] : co2 + h2o <==> h2co3
is: ENSMUSG00000032373.7
reactant: 223605
product: 223629
is: ENSMUSG00000031883.5
name: carboxylic acid dissociation
fast: false
is: ENSMUSG00000027556.7
reactant: 223617
is: ENSMUSG00000028463.5
is: ENSMUSG00000027559.3

223605
type: SpeciesReference
stoichiometry: 1.0
species: 168436

223629
type: SpeciesReference
stoichiometry: 1.0
species: 175518

175518
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: carbonic acid_H2CO3

223617
type: SpeciesReference
stoichiometry: 1.0
species: 175614

949199
type: Reaction
is: ENSMUSG00000071711.3
is: http://identifiers.org/ec-code/2.8.1.2
product: 224570
reactant: 224558
notes: R_MCPST subsystem: Cysteine Metabolism R_MCPST equation: [c] : cyan + mercppyr --> h + pyr + tcynt
name: _3-mercaptopyruvate sulfurtransferase
product: 224594
reactant: 224546
reversible: false
fast: false
product: 224582

224570
type: SpeciesReference
stoichiometry: 1.0
species: 184819

224558
type: SpeciesReference
stoichiometry: 1.0
species: 180692

224594
type: SpeciesReference
stoichiometry: 1.0
species: 175722

224546
type: SpeciesReference
stoichiometry: 1.0
species: 169654

224582
type: SpeciesReference
stoichiometry: 1.0
species: 186332

172523
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2

184411
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Prostaglandin D2_C20H31O5

947829
type: Reaction
is: http://identifiers.org/ec-code/3.5.3.11
product: 212608
reactant: 212584
reversible: false
reactant: 212572
name: agmatinase (m)
notes: R_AGMTm subsystem: Arginine and Proline Metabolism R_AGMTm equation: [m] : agm + h2o --> ptrc + urea
fast: false
is: ENSMUSG00000040706.3
product: 212596

212608
type: SpeciesReference
stoichiometry: 1.0
species: 188020

212584
type: SpeciesReference
stoichiometry: 1.0
species: 165677

165677
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Agmatine_C5H16N4

212572
type: SpeciesReference
stoichiometry: 1.0
species: 175662

212596
type: SpeciesReference
stoichiometry: 1.0
species: 184711

184711
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Putrescine_C4H14N2

186670
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Tetrahydrobiopterin-4a-carbinolamine_C9H15N5O4

948646
type: Reaction
is: ENSMUSG00000024210.1
reactant: 219172
reactant: 219208
fast: false
is: http://identifiers.org/ec-code/3.6.1.52
product: 219293
product: 219233
product: 219257
reversible: false
product: 219305
notes: R_PMI1346PHn subsystem: Inositol Phosphate Metabolism R_PMI1346PHn equation: [n] : h2o + ppmi1346p --> h + mi13456p + pi R_PMI1346PH subsystem: Inositol Phosphate Metabolism R_PMI1346PH equation: [c] : h2o + ppmi1346p --> h + mi13456p + pi R_PMI12346PHn subsystem: Inositol Phosphate Metabolism R_PMI12346PHn equation: [n] : h2o + ppmi12346p --> h + minohp + pi R_PMI12346PH subsystem: Inositol Phosphate Metabolism R_PMI12346PH equation: [c] : h2o + ppmi12346p --> h + minohp + pi
product: 219245
reactant: 219220
reactant: 219196
reactant: 219184
product: 219281
product: 219269
is: ENSMUSG00000032594.3
product: 219317
reactant: 219160

219172
type: SpeciesReference
stoichiometry: 1.0
species: 184002

184002
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Diphosphoinositol tetrakisphosphate_C6H7O24P6

219208
type: SpeciesReference
stoichiometry: 1.0
species: 183990

183990
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: _5-Diphosphoinositol pentakisphosphate_C6H6O27P7

219293
type: SpeciesReference
stoichiometry: 2.0
species: 175722

219233
type: SpeciesReference
stoichiometry: 2.0
species: 183652

219257
type: SpeciesReference
stoichiometry: 2.0
species: 175782

219305
type: SpeciesReference
stoichiometry: 2.0
species: 183712

183712
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Phosphate_HO4P

219245
type: SpeciesReference
stoichiometry: 1.0
species: 181030

181030
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: myo-Inositol hexakisphosphate_C6H6O24P6

219220
type: SpeciesReference
stoichiometry: 1.0
species: 184014

184014
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Diphosphoinositol tetrakisphosphate_C6H7O24P6

219196
type: SpeciesReference
stoichiometry: 2.0
species: 175674

219184
type: SpeciesReference
stoichiometry: 2.0
species: 175614

219281
type: SpeciesReference
stoichiometry: 1.0
species: 180837

180837
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1D-myo-Inositol 1,3,4,5,6-pentakisphosphate_C6H7O21P5

219269
type: SpeciesReference
stoichiometry: 1.0
species: 180849

180849
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: _1D-myo-Inositol 1,3,4,5,6-pentakisphosphate_C6H7O21P5

219317
type: SpeciesReference
stoichiometry: 1.0
species: 181042

181042
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: myo-Inositol hexakisphosphate_C6H6O24P6

219160
type: SpeciesReference
stoichiometry: 1.0
species: 183978

183978
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-Diphosphoinositol pentakisphosphate_C6H6O27P7

167978
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Choline phosphate_C5H13NO4P

953781
type: Reaction
product: 270027
product: 270002
product: 269990
reactant: 269917
is: http://identifiers.org/ec-code/2.5.1.29
product: 269978
reactant: 269893
is: http://identifiers.org/ec-code/2.4.1.155
is: http://identifiers.org/ec-code/2.5.1.10
product: 270014
is: http://identifiers.org/ec-code/2.5.1.1
is: ENSMUSG00000021302.7
reactant: 269905
reactant: 269941
notes: R_DMATT subsystem: Cholesterol Metabolism R_DMATT equation: [c] : dmpp + ipdp --> grdp + ppi R_FRTT subsystem: Cholesterol Metabolism R_FRTT equation: [c] : frdp + ipdp --> ggdp + ppi R_M16N6Tg subsystem: N-Glycan Biosynthesis R_M16N6Tg equation: [g] : n3m2masn + uacgam --> h + n4m2masn + udp R_GRTT subsystem: Cholesterol Metabolism R_GRTT equation: [c] : grdp + ipdp --> frdp + ppi
fast: false
product: 269965
reactant: 269929
reactant: 269881
reversible: false
product: 269953

270027
type: SpeciesReference
stoichiometry: 3.0
species: 183917

270002
type: SpeciesReference
stoichiometry: 1.0
species: 175746

269990
type: SpeciesReference
stoichiometry: 1.0
species: 181364

181364
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: ((N-acetyl-D-glucosaminyl)4-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C66H109N6O45X

269917
type: SpeciesReference
stoichiometry: 1.0
species: 171196

269978
type: SpeciesReference
stoichiometry: 1.0
species: 187608

269893
type: SpeciesReference
stoichiometry: 1.0
species: 172896

172896
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Farnesyl diphosphate_C15H25O7P2

270014
type: SpeciesReference
stoichiometry: 1.0
species: 174226

174226
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Geranylgeranyl diphosphate_C20H33O7P2

269905
type: SpeciesReference
stoichiometry: 1.0
species: 187572

269941
type: SpeciesReference
stoichiometry: 3.0
species: 177434

177434
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Isopentenyl diphosphate_C5H9O7P2

269965
type: SpeciesReference
stoichiometry: 1.0
species: 172896

269929
type: SpeciesReference
stoichiometry: 1.0
species: 181327

181327
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: ((N-acetyl-D-glucosaminyl)3-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C58H96N5O40X

269881
type: SpeciesReference
stoichiometry: 1.0
species: 175184

175184
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Geranyl diphosphate_C10H17O7P2

269953
type: SpeciesReference
stoichiometry: 1.0
species: 175184

178858
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II (core 4-linked)_C89H142N7O72S3X

163884
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Protein N6,N6-dimethyl-L-lysine_C2H7X

945818
type: Reaction
modifier: 194889
modifier: 194876
modifier: 194852
reversible: false
is: ENSMUSG00000030246.4
modifier: 194816
notes: R_LDH_L subsystem: Glycolysis/Gluconeogenesis R_LDH_L equation: [c] : lac-L + nad <==> h + nadh + pyr R_MCLOR subsystem: Cysteine Metabolism R_MCLOR equation: [c] : mercplac + nad <==> h + mercppyr + nadh R_HPYRR2x subsystem: Glyoxylate and Dicarboxylate Metabolism R_HPYRR2x equation: [c] : h + hpyr + nadh --> glyc-S + nad R_2HBO subsystem: Propanoate Metabolism R_2HBO equation: [c] : 2hb + nad <==> 2obut + h + nadh R_GLXO1 subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO1 equation: [c] : glx + h2o + nad --> (2) h + nadh + oxa
is: http://identifiers.org/ec-code/1.1.1.27
reactant: 194732
reactant: 194720
product: 194780
modifier: 194828
reactant: 194684
reactant: 194708
modifier: 194913
fast: false
modifier: 194864
modifier: 194840
reactant: 194744
is: ENSMUSG00000030851.5
reactant: 194696
is: ENSMUSG00000063229.6
product: 194804
product: 194756
is: http://identifiers.org/ec-code/1.2.3.5
product: 194768
product: 194792
modifier: 194901

180680
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Mercaptolactate_C3H5O3S

194732
type: SpeciesReference
stoichiometry: 1.0
species: 175722

194720
type: SpeciesReference
stoichiometry: 1.0
species: 174588

194780
type: SpeciesReference
stoichiometry: 1.0
species: 174757

174757
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: (S)-Glycerate_C3H5O4

194684
type: SpeciesReference
stoichiometry: 1.0
species: 181437

194708
type: SpeciesReference
stoichiometry: 1.0
species: 175614

194744
type: SpeciesReference
stoichiometry: 1.0
species: 181510

194696
type: SpeciesReference
stoichiometry: 1.0
species: 176433

176433
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Hydroxypyruvate_C3H3O4

194804
type: SpeciesReference
stoichiometry: 1.0
species: 181510

194756
type: SpeciesReference
stoichiometry: 1.0
species: 182719

194768
type: SpeciesReference
stoichiometry: 1.0
species: 181437

194792
type: SpeciesReference
stoichiometry: 2.0
species: 175722

952663
type: Reaction
is: ENSMUSG00000045625.2
reactant: 259536
reversible: false
reactant: 259573
product: 259645
notes: R_H6MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6MTer_L equation: [r] : (0.1) dolmanp_L + m2emgacpail_hs --> (0.1) dolp_L + h + m3emgacpail_hs R_H8MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8MTer_L equation: [r] : (0.1) dolmanp_L + gpi_hs --> (0.1) dolp_L + h + m(em)3gacpail_hs R_H6MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6MTer_U equation: [r] : (0.1) dolmanp_U + m2emgacpail_hs --> (0.1) dolp_U + h + m3emgacpail_hs R_H7MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7MTer_U equation: [r] : (0.1) dolmanp_U + em2emgacpail_hs --> (0.1) dolp_U + h + mem2emgacpail_hs R_H7MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7MTer_L equation: [r] : (0.1) dolmanp_L + em2emgacpail_hs --> (0.1) dolp_L + h + mem2emgacpail_hs R_H8MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8MTer_U equation: [r] : (0.1) dolmanp_U + gpi_hs --> (0.1) dolp_U + h + m(em)3gacpail_hs
product: 259597
product: 259633
product: 259621
product: 259609
reactant: 259561
product: 259585
reactant: 259549
reactant: 259524
fast: false

259536
type: SpeciesReference
stoichiometry: 2.0
species: 175108

259573
type: SpeciesReference
stoichiometry: 1.0
species: 171367

259645
type: SpeciesReference
stoichiometry: 6.0
species: 175794

259597
type: SpeciesReference
stoichiometry: 2.0
species: 180282

259633
type: SpeciesReference
stoichiometry: 2.0
species: 179968

259621
type: SpeciesReference
stoichiometry: 2.0
species: 180596

259609
type: SpeciesReference
stoichiometry: 1.0
species: 171439

259561
type: SpeciesReference
stoichiometry: 2.0
species: 179920

259585
type: SpeciesReference
stoichiometry: 1.0
species: 171415

259549
type: SpeciesReference
stoichiometry: 1.0
species: 171391

259524
type: SpeciesReference
stoichiometry: 2.0
species: 172077

951931
type: Reaction
product: 250340
reactant: 250268
modifier: 250462
modifier: 250426
product: 250328
reactant: 250208
fast: false
modifier: 250438
product: 250304
reactant: 250196
product: 250352
reactant: 250280
is: http://identifiers.org/ec-code/1.1.1.2
reactant: 250232
is: http://identifiers.org/ec-code/1.1.1.21
product: 250401
product: 250292
product: 250377
reactant: 250244
reactant: 250184
notes: R_ARABR subsystem: Pentose and Glucuronate Interconversions R_ARABR equation: [c] : arab-L + h + nadph --> abt + nadp R_LALDO2 subsystem: Pyruvate Metabolism R_LALDO2 equation: [c] : h + mthgxl + nadph --> lald-D + nadp R_ALR3 subsystem: Pyruvate Metabolism R_ALR3 equation: [c] : acetol + h + nadph --> 12ppd-S + nadp R_ALR subsystem: Glycine, Serine, and Threonine Metabolism R_ALR equation: [c] : h2o + mthgxl + nadp --> (2) h + nadph + pyr R_SBTR subsystem: Fructose and Mannose Metabolism R_SBTR equation: [c] : glc-D + h + nadph --> nadp + sbt-D R_GALOR subsystem: Galactose metabolism R_GALOR equation: [c] : gal + h + nadph <==> galt + nadp R_ALR2 subsystem: Pyruvate Metabolism R_ALR2 equation: [c] : h + mthgxl + nadph --> acetol + nadp R_PPDOy subsystem: Pyruvate Metabolism R_PPDOy equation: [c] : h + lald-D + nadph --> 12ppd-R + nadp
product: 250316
is: ENSMUSG00000025955.6
reversible: false
reactant: 250220
is: ENSMUSG00000001642.9
product: 250364
product: 250389
reactant: 250256
modifier: 250450
is: ENSMUSG00000045410.8
modifier: 250414

250340
type: SpeciesReference
stoichiometry: 6.0
species: 181558

250268
type: SpeciesReference
stoichiometry: 6.0
species: 175722

250328
type: SpeciesReference
stoichiometry: 1.0
species: 184819

250208
type: SpeciesReference
stoichiometry: 1.0
species: 166519

250304
type: SpeciesReference
stoichiometry: 1.0
species: 164414

250196
type: SpeciesReference
stoichiometry: 1.0
species: 181558

250352
type: SpeciesReference
stoichiometry: 1.0
species: 179122

250280
type: SpeciesReference
stoichiometry: 6.0
species: 181631

250232
type: SpeciesReference
stoichiometry: 1.0
species: 174274

250401
type: SpeciesReference
stoichiometry: 1.0
species: 181631

250292
type: SpeciesReference
stoichiometry: 1.0
species: 160907

250377
type: SpeciesReference
stoichiometry: 1.0
species: 164655

250244
type: SpeciesReference
stoichiometry: 1.0
species: 179122

250184
type: SpeciesReference
stoichiometry: 3.0
species: 181198

250316
type: SpeciesReference
stoichiometry: 1.0
species: 160895

250220
type: SpeciesReference
stoichiometry: 1.0
species: 175614

250364
type: SpeciesReference
stoichiometry: 1.0
species: 185349

250389
type: SpeciesReference
stoichiometry: 2.0
species: 175722

250256
type: SpeciesReference
stoichiometry: 1.0
species: 164655

161915
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Hydroxypropionyl-CoA_C24H36N7O18P3S

952423
type: Reaction
reactant: 256285
notes: R_3HPCOAHYD subsystem: beta-Alanine metabolism R_3HPCOAHYD equation: [c] : 3hpcoa + h2o --> 3hpp + coa + h
product: 256333
fast: false
name: _3-hydroxyisobutyryl-Coenzyme A hydrolase
is: http://identifiers.org/ec-code/3.1.2.4
reversible: false
is: ENSMUSG00000041426.5
product: 256309
product: 256321
reactant: 256297

256285
type: SpeciesReference
stoichiometry: 1.0
species: 161915

256333
type: SpeciesReference
stoichiometry: 1.0
species: 175722

256309
type: SpeciesReference
stoichiometry: 1.0
species: 168509

256321
type: SpeciesReference
stoichiometry: 1.0
species: 161951

161951
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Hydroxypropanoate_C3H5O3

256297
type: SpeciesReference
stoichiometry: 1.0
species: 175614

947588
type: Reaction
name: glutaminase (mitochondrial)
is: ENSMUSG00000044005.5
product: 210897
reactant: 210873
product: 210885
reversible: false
is: ENSMUSG00000026103.6
reactant: 210861
is: http://identifiers.org/ec-code/3.5.1.2
fast: false
notes: R_GLUNm subsystem: Glutamate metabolism R_GLUNm equation: [m] : gln-L + h2o --> glu-L + nh4

210897
type: SpeciesReference
stoichiometry: 1.0
species: 174478

210873
type: SpeciesReference
stoichiometry: 1.0
species: 175662

210885
type: SpeciesReference
stoichiometry: 1.0
species: 181776

210861
type: SpeciesReference
stoichiometry: 1.0
species: 174406

174406
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Glutamine_C5H10N2O3

184278
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Proline_C5H9NO2

945690
type: Reaction
is: ENSMUSG00000048755.7
name: Malonyl-CoA-ACP transacylase, mitochondrial
reactant: 193525
notes: R_MCOATAm subsystem: Fatty Acid Metabolism R_MCOATAm equation: [m] : ACP + malcoa <==> coa + malACP
product: 193537
reactant: 193513
fast: false
product: 193549
reversible: true
is: http://identifiers.org/ec-code/2.3.1.39

193525
type: SpeciesReference
stoichiometry: 1.0
species: 163691

163691
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: acyl carrier protein_C11H21N2O7PRS

193537
type: SpeciesReference
stoichiometry: 1.0
species: 168545

193513
type: SpeciesReference
stoichiometry: 1.0
species: 180391

193549
type: SpeciesReference
stoichiometry: 1.0
species: 180343

180343
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Malonyl-[acyl-carrier protein]_C14H22N2O10PRS

172234
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _16-Glucuronide-estriol_C24H32O9

952591
type: Reaction
reactant: 259090
product: 259150
is: http://identifiers.org/ec-code/2.4.99.6
notes: R_ST3GAL31g subsystem: Blood Group Biosynthesis R_ST3GAL31g equation: [g] : cmpacna + galacglcgalgluside_hs --> acngalacglcgalgluside_hs + cmp + h R_S23T3g subsystem: Keratan sulfate biosynthesis R_S23T3g equation: [g] : cmpacna + l2fn2m2masn --> cmp + h + ksi_pre1
product: 259114
product: 259138
reversible: false
reactant: 259078
is: ENSMUSG00000028538.4
reactant: 259102
fast: false
product: 259126

259090
type: SpeciesReference
stoichiometry: 1.0
species: 179002

179002
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550

259150
type: SpeciesReference
stoichiometry: 2.0
species: 168340

259114
type: SpeciesReference
stoichiometry: 1.0
species: 178244

178244
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 1_C79H129N5O57X

259138
type: SpeciesReference
stoichiometry: 1.0
species: 165172

259078
type: SpeciesReference
stoichiometry: 2.0
species: 168388

259102
type: SpeciesReference
stoichiometry: 1.0
species: 173691

259126
type: SpeciesReference
stoichiometry: 2.0
species: 175746

947264
type: Reaction
notes: R_GF6PTA subsystem: Aminosugar Metabolism R_GF6PTA equation: [c] : f6p + gln-L --> gam6p + glu-L
name: glutamine-fructose-6-phosphate transaminase
reversible: false
is: ENSMUSG00000020363.5
reactant: 208008
is: http://identifiers.org/ec-code/2.6.1.16
product: 208033
reactant: 208020
is: ENSMUSG00000029992.6
product: 208045
fast: false

208008
type: SpeciesReference
stoichiometry: 1.0
species: 174382

208033
type: SpeciesReference
stoichiometry: 1.0
species: 173875

208020
type: SpeciesReference
stoichiometry: 1.0
species: 172475

208045
type: SpeciesReference
stoichiometry: 1.0
species: 174442

182130
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Trimethyl-2-aminoethylphosphonate_C5H13NO3P

945610
type: Reaction
product: 192992
reactant: 192956
is: ENSMUSG00000028911.7
reactant: 192968
is: ENSMUSG00000021336.7
is: ENSMUSG00000078134.1
name: phosphate transport in/out via three Na+ symporter (irreversible)
is: ENSMUSG00000036110.6
reversible: false
fast: false
product: 192980
is: ENSMUSG00000021335.6
notes: R_PIt7ir subsystem: Transport, Extracellular R_PIt7ir equation: (3) na1[e] + pi[e] --> (3) na1[c] + pi[c]

192992
type: SpeciesReference
stoichiometry: 3.0
species: 181377

192956
type: SpeciesReference
stoichiometry: 1.0
species: 183664

183664
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Phosphate_HO4P

192968
type: SpeciesReference
stoichiometry: 3.0
species: 181389

192980
type: SpeciesReference
stoichiometry: 1.0
species: 183652

948706
type: Reaction
product: 219932
reactant: 219847
product: 219920
reversible: false
reactant: 219884
fast: false
reactant: 219835
reactant: 219859
product: 219908
product: 219896
is: ENSMUSG00000050445.4
notes: R_P4508B13r subsystem: Bile Acid Biosynthesis R_P4508B13r equation: [r] : h + nadh + o2 + xol7aone --> h2o + nad + xoldiolone R_P4508B11r subsystem: Bile Acid Biosynthesis R_P4508B11r equation: [r] : h + nadph + o2 + xol7aone --> h2o + nadp + xoldiolone
reactant: 219871

219932
type: SpeciesReference
stoichiometry: 1.0
species: 181486

219847
type: SpeciesReference
stoichiometry: 2.0
species: 188490

188490
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _7alpha-Hydroxycholest-4-en-3-one_C27H44O2

219920
type: SpeciesReference
stoichiometry: 2.0
species: 188514

188514
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _7alpha,12alpha-Dihydroxycholest-4-en-3-one_C27H44O3

219884
type: SpeciesReference
stoichiometry: 2.0
species: 175794

219835
type: SpeciesReference
stoichiometry: 2.0
species: 182202

219859
type: SpeciesReference
stoichiometry: 1.0
species: 181534

219908
type: SpeciesReference
stoichiometry: 1.0
species: 181607

219896
type: SpeciesReference
stoichiometry: 2.0
species: 175686

219871
type: SpeciesReference
stoichiometry: 1.0
species: 181667

948490
type: Reaction
fast: false
product: 218040
reversible: false
is: http://identifiers.org/ec-code/2.8.2.23
is: ENSMUSG00000039628.6
product: 218065
is: ENSMUSG00000047759.5
notes: R_S3T3g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T3g equation: [g] : hs_pre15 + paps --> h + hspg + pap
reactant: 218028
product: 218052
name: heparin-glucosamine 3-O-sulfotransferase
reactant: 218016

218040
type: SpeciesReference
stoichiometry: 1.0
species: 175746

218065
type: SpeciesReference
stoichiometry: 1.0
species: 183120

218028
type: SpeciesReference
stoichiometry: 1.0
species: 183143

218052
type: SpeciesReference
stoichiometry: 1.0
species: 176951

176951
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: heparan sulfate proteoglycan_C79H113N5O101S12X

218016
type: SpeciesReference
stoichiometry: 1.0
species: 176830

176830
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: heparan sulfate, precursor 15_C79H114N5O98S11X

161623
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: _3,4-Dihydroxy-L-phenylalanine_C9H11NO4

955523
type: Reaction
product: 288457
product: 288445
product: 288421
product: 288397
product: 288481
reactant: 288312
reversible: false
product: 288433
reactant: 288360
reactant: 288373
notes: R_ARABR subsystem: Pentose and Glucuronate Interconversions R_ARABR equation: [c] : arab-L + h + nadph --> abt + nadp R_LALDO2 subsystem: Pyruvate Metabolism R_LALDO2 equation: [c] : h + mthgxl + nadph --> lald-D + nadp R_LALDO2x subsystem: Pyruvate Metabolism R_LALDO2x equation: [c] : h + mthgxl + nadh --> lald-D + nad R_ALR3 subsystem: Pyruvate Metabolism R_ALR3 equation: [c] : acetol + h + nadph --> 12ppd-S + nadp R_PPDOx subsystem: Pyruvate Metabolism R_PPDOx equation: [c] : h + lald-D + nadh --> 12ppd-R + nad R_SBTR subsystem: Fructose and Mannose Metabolism R_SBTR equation: [c] : glc-D + h + nadph --> nadp + sbt-D R_ALR2 subsystem: Pyruvate Metabolism R_ALR2 equation: [c] : h + mthgxl + nadph --> acetol + nadp R_PPDOy subsystem: Pyruvate Metabolism R_PPDOy equation: [c] : h + lald-D + nadph --> 12ppd-R + nadp
reactant: 288336
fast: false
product: 288469
reactant: 288324
reactant: 288385
is: http://identifiers.org/ec-code/1.1.1.21
reactant: 288348
product: 288409
reactant: 288300
is: ENSMUSG00000028743.6

288457
type: SpeciesReference
stoichiometry: 2.0
species: 179122

288445
type: SpeciesReference
stoichiometry: 6.0
species: 181558

288421
type: SpeciesReference
stoichiometry: 2.0
species: 160895

288397
type: SpeciesReference
stoichiometry: 1.0
species: 160907

288481
type: SpeciesReference
stoichiometry: 1.0
species: 164655

288312
type: SpeciesReference
stoichiometry: 1.0
species: 166519

288433
type: SpeciesReference
stoichiometry: 2.0
species: 181437

288360
type: SpeciesReference
stoichiometry: 8.0
species: 175722

288373
type: SpeciesReference
stoichiometry: 2.0
species: 181510

288336
type: SpeciesReference
stoichiometry: 2.0
species: 179122

288469
type: SpeciesReference
stoichiometry: 1.0
species: 185349

288324
type: SpeciesReference
stoichiometry: 1.0
species: 174274

288385
type: SpeciesReference
stoichiometry: 6.0
species: 181631

288348
type: SpeciesReference
stoichiometry: 1.0
species: 164655

288409
type: SpeciesReference
stoichiometry: 1.0
species: 164414

288300
type: SpeciesReference
stoichiometry: 3.0
species: 181198

953889
type: Reaction
reactant: 270882
product: 270943
reversible: false
is: ENSMUSG00000028992.5
is: http://identifiers.org/ec-code/2.7.7.18
reactant: 270894
reactant: 270906
notes: R_NNATn subsystem: NAD Metabolism R_NNATn equation: [n] : atp + h + nicrnt --> dnad + ppi R_NMNATn subsystem: NAD Metabolism R_NMNATn equation: [n] : atp + h + nmn --> nad + ppi
is: http://identifiers.org/ec-code/2.7.7.1
fast: false
product: 270955
product: 270931
reactant: 270918

270882
type: SpeciesReference
stoichiometry: 1.0
species: 181861

181861
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Nicotinate D-ribonucleotide_C11H12NO9P

270943
type: SpeciesReference
stoichiometry: 2.0
species: 183941

183941
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Diphosphate_HO7P2

270894
type: SpeciesReference
stoichiometry: 2.0
species: 175782

270906
type: SpeciesReference
stoichiometry: 2.0
species: 166940

270955
type: SpeciesReference
stoichiometry: 1.0
species: 181474

270931
type: SpeciesReference
stoichiometry: 1.0
species: 171270

171270
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Deamino-NAD+_C21H24N6O15P2

270918
type: SpeciesReference
stoichiometry: 1.0
species: 181934

181934
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: NMN_C11H14N2O8P

178509
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 6_C107H174N7O80SX

160623
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19

182900
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: phosphatidylinositol-3,4-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2

167579
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Cob(I)alamin_C62H88CoN13O14P

176637
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 24_C31H50NO26

165197
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N2-Acetyl-L-ornithine_C7H14N2O3

163956
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: R group 2 Coenzyme A homo sapiens_XCO2C21H31N7O15P3S

181728
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Nicotinamide_C6H6N2O

954057
type: Reaction
reversible: false
reactant: 273583
product: 273646
reactant: 273570
product: 273596
product: 273621
product: 273609
is: ENSMUSG00000079469.2
reactant: 273557
product: 273633
reactant: 273544
fast: false
notes: R_BMTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_BMTer_L equation: [r] : (0.1) dolmanp_L + memgacpail_hs --> (0.1) dolp_L + h + m2emgacpail_hs R_BMTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_BMTer_U equation: [r] : (0.1) dolmanp_U + memgacpail_hs --> (0.1) dolp_U + h + m2emgacpail_hs R_H3MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3MTer_L equation: [r] : (0.1) dolmanp_L + m2gacpail_hs --> (0.1) dolp_L + h + m3gacpail_hs R_H3MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3MTer_U equation: [r] : (0.1) dolmanp_U + m2gacpail_hs --> (0.1) dolp_U + h + m3gacpail_hs

273583
type: SpeciesReference
stoichiometry: 1.0
species: 171367

273646
type: SpeciesReference
stoichiometry: 4.0
species: 175794

273570
type: SpeciesReference
stoichiometry: 1.0
species: 171391

273596
type: SpeciesReference
stoichiometry: 1.0
species: 171415

273621
type: SpeciesReference
stoichiometry: 1.0
species: 171439

273609
type: SpeciesReference
stoichiometry: 2.0
species: 179980

273557
type: SpeciesReference
stoichiometry: 2.0
species: 179932

179932
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: dimannosyl-glucosaminyl-acylphosphatidylinositol (H3)_C43H78NO24PFULLRCO2FULLR2CO2

273633
type: SpeciesReference
stoichiometry: 2.0
species: 179920

273544
type: SpeciesReference
stoichiometry: 2.0
species: 180620

180620
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (mannosyl),(phosphoethanolaminyl)-mannosyl-glucosylaminyl-acylphosphatidylinositol (B)_C45H84N2O27P2FULLRCO2FULLR2CO2

186284
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: paclitaxel_C47H31NO14

950150
type: Reaction
is: ENSMUSG00000018547.7
product: 235302
is: ENSMUSG00000026737.4
is: ENSMUSG00000025949.8
reversible: false
product: 235290
notes: R_PI4P5K subsystem: Glycerophospholipid Metabolism R_PI4P5K equation: [c] : atp + pail4p_hs --> adp + h + pail45p_hs
is: ENSMUSG00000025417.6
fast: false
is: http://identifiers.org/ec-code/2.7.1.68
product: 235314
reactant: 235278
name: phosphatidylinositol 4-phosphate 5-kinase
reactant: 235266

235302
type: SpeciesReference
stoichiometry: 1.0
species: 165387

235290
type: SpeciesReference
stoichiometry: 1.0
species: 182962

235314
type: SpeciesReference
stoichiometry: 1.0
species: 175722

235278
type: SpeciesReference
stoichiometry: 1.0
species: 182987

235266
type: SpeciesReference
stoichiometry: 1.0
species: 166904

947516
type: Reaction
reactant: 210416
reactant: 210392
is: http://identifiers.org/ec-code/1.4.3.5
reversible: true
reactant: 210404
fast: false
reactant: 210428
is: ENSMUSG00000018659.4
product: 210452
product: 210440
notes: R_PDX5PO subsystem: Vitamin B6 Metabolism R_PDX5PO equation: [c] : o2 + pdx5p <==> h2o2 + pydx5p R_PYAM5POr subsystem: Vitamin B6 Metabolism R_PYAM5POr equation: [c] : h2o + o2 + pyam5p <==> h2o2 + nh4 + pydx5p
product: 210464

210416
type: SpeciesReference
stoichiometry: 1.0
species: 175614

210392
type: SpeciesReference
stoichiometry: 1.0
species: 183289

210404
type: SpeciesReference
stoichiometry: 1.0
species: 184735

210428
type: SpeciesReference
stoichiometry: 2.0
species: 182154

210452
type: SpeciesReference
stoichiometry: 2.0
species: 175542

210440
type: SpeciesReference
stoichiometry: 1.0
species: 181752

210464
type: SpeciesReference
stoichiometry: 2.0
species: 184759

184759
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Pyridoxal 5'-phosphate_C8H8NO6P

179558
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Linoelaidyl carnitine_C25H45NO4

945914
type: Reaction
reactant: 195526
product: 195538
name: b-galactosidase, extracellular
reversible: false
fast: false
is: http://identifiers.org/ec-code/3.2.1.23
notes: R_LACZe subsystem: Galactose metabolism R_LACZe equation: [e] : h2o + lcts --> gal + glc-D
product: 195550
is: ENSMUSG00000026354.7
reactant: 195514

195526
type: SpeciesReference
stoichiometry: 1.0
species: 175626

195538
type: SpeciesReference
stoichiometry: 1.0
species: 173595

195550
type: SpeciesReference
stoichiometry: 1.0
species: 174286

195514
type: SpeciesReference
stoichiometry: 1.0
species: 179194

179194
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Lactose_C12H22O11

185241
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: de-Fuc, reducing GlcNAc removed form of PA6 (w/o peptide linkage)_C76H123N5O57

954333
type: Reaction
reactant: 275853
name: cytochrome P450 lanosterol 14-alpha-demethylase
is: ENSMUSG00000001467.3
product: 275866
reactant: 275829
product: 275890
notes: R_LNS14DMr subsystem: Cholesterol Metabolism R_LNS14DMr equation: [r] : (2) h + lanost + (3) nadph + (3) o2 --> 44mctr + for + (4) h2o + (3) nadp
fast: false
product: 275902
reactant: 275841
reversible: false
reactant: 275817
is: http://identifiers.org/ec-code/1.14.14.1
product: 275878

275853
type: SpeciesReference
stoichiometry: 2.0
species: 175794

275866
type: SpeciesReference
stoichiometry: 1.0
species: 172836

172836
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Formate_CH1O2

275829
type: SpeciesReference
stoichiometry: 1.0
species: 179182

179182
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Lanosterol_C30H50O

275890
type: SpeciesReference
stoichiometry: 3.0
species: 181607

275902
type: SpeciesReference
stoichiometry: 1.0
species: 162374

162374
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _4,4-dimethylcholesta-8,14,24-trienol_C29H46O

275841
type: SpeciesReference
stoichiometry: 3.0
species: 181667

275817
type: SpeciesReference
stoichiometry: 3.0
species: 182202

275878
type: SpeciesReference
stoichiometry: 4.0
species: 175686

180004
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (alpha-D-Mannosyl)4-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1540H2528N20O420P20

951967
type: Reaction
product: 250994
reactant: 250958
product: 251006
fast: false
is: ENSMUSG00000024843.7
reactant: 250970
is: http://identifiers.org/ec-code/2.7.1.82
reactant: 250982
is: http://identifiers.org/ec-code/2.7.1.32
product: 251030
reversible: false
product: 251018
notes: R_ETHAK subsystem: Glycerophospholipid Metabolism R_ETHAK equation: [c] : atp + etha --> adp + ethamp + h R_CHOLK subsystem: Glycerophospholipid Metabolism R_CHOLK equation: [c] : atp + chol --> adp + cholp + h

250994
type: SpeciesReference
stoichiometry: 1.0
species: 172379

250958
type: SpeciesReference
stoichiometry: 1.0
species: 172367

172367
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Ethanolamine_C2H8NO

251006
type: SpeciesReference
stoichiometry: 1.0
species: 167978

250970
type: SpeciesReference
stoichiometry: 2.0
species: 166904

250982
type: SpeciesReference
stoichiometry: 1.0
species: 167796

251030
type: SpeciesReference
stoichiometry: 2.0
species: 175722

251018
type: SpeciesReference
stoichiometry: 2.0
species: 165387

947001
type: Reaction
product: 205498
notes: R_GLUPRT subsystem: IMP Biosynthesis R_GLUPRT equation: [c] : gln-L + h2o + prpp --> glu-L + ppi + pram
is: ENSMUSG00000029246.7
is: http://identifiers.org/ec-code/2.4.2.14
reactant: 205462
reactant: 205438
fast: false
product: 205474
product: 205486
reversible: false
name: glutamine phosphoribosyldiphosphate amidotransferase
reactant: 205450

205498
type: SpeciesReference
stoichiometry: 1.0
species: 183917

205462
type: SpeciesReference
stoichiometry: 1.0
species: 175614

205438
type: SpeciesReference
stoichiometry: 1.0
species: 174382

205474
type: SpeciesReference
stoichiometry: 1.0
species: 184098

184098
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-Phospho-beta-D-ribosylamine_C5H11NO7P

205486
type: SpeciesReference
stoichiometry: 1.0
species: 174442

205450
type: SpeciesReference
stoichiometry: 1.0
species: 184579

945367
type: Reaction
product: 190929
is: ENSMUSG00000062937.4
reversible: false
product: 190917
name: _5'-methylthioadenosine phosphorylase
is: http://identifiers.org/ec-code/2.4.2.28
notes: R_MTAP subsystem: Arginine and Proline Metabolism R_MTAP equation: [c] : 5mta + pi --> 5mdr1p + ade
reactant: 190905
fast: false
reactant: 190893

190929
type: SpeciesReference
stoichiometry: 1.0
species: 163245

163245
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _5-Methylthio-5-deoxy-D-ribose 1-phosphate_C6H11O7PS

190917
type: SpeciesReference
stoichiometry: 1.0
species: 165259

190905
type: SpeciesReference
stoichiometry: 1.0
species: 163269

190893
type: SpeciesReference
stoichiometry: 1.0
species: 183652

180451
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Maltotriose_C18H32O16

178954
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 6_C69H111N6O51SX

945318
type: Reaction
reactant: 190591
reactant: 190579
notes: R_SLCBK1 subsystem: Sphingolipid Metabolism R_SLCBK1 equation: [c] : atp + sphgn --> adp + h + sph1p R_SPHK21c subsystem: Sphingolipid Metabolism R_SPHK21c equation: [c] : atp + sphings --> adp + h + sphs1p
reactant: 190567
is: ENSMUSG00000057342.6
fast: false
product: 190639
product: 190627
reversible: false
product: 190603
product: 190615

190591
type: SpeciesReference
stoichiometry: 1.0
species: 185741

185741
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Sphinganine_C18H40NO2

190579
type: SpeciesReference
stoichiometry: 1.0
species: 185765

185765
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Sphingosine_C18H38NO2

190567
type: SpeciesReference
stoichiometry: 2.0
species: 166904

190639
type: SpeciesReference
stoichiometry: 2.0
species: 175722

190627
type: SpeciesReference
stoichiometry: 2.0
species: 165387

190603
type: SpeciesReference
stoichiometry: 1.0
species: 185716

185716
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Sphinganine 1-phosphate_C18H39NO5P

190615
type: SpeciesReference
stoichiometry: 1.0
species: 185837

162774
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: D-4'-Phosphopantothenate_C9H15NO8P

946374
type: Reaction
reactant: 199280
notes: R_ACITL subsystem: Citric Acid Cycle R_ACITL equation: [c] : atp + cit + coa --> accoa + adp + oaa + pi
reactant: 199268
reversible: false
fast: false
product: 199305
product: 199317
product: 199341
product: 199329
name: ATP-Citrate lyase
reactant: 199292
is: ENSMUSG00000020917.8

199280
type: SpeciesReference
stoichiometry: 1.0
species: 168136

199268
type: SpeciesReference
stoichiometry: 1.0
species: 168509

199305
type: SpeciesReference
stoichiometry: 1.0
species: 165387

199317
type: SpeciesReference
stoichiometry: 1.0
species: 182286

199341
type: SpeciesReference
stoichiometry: 1.0
species: 164583

199329
type: SpeciesReference
stoichiometry: 1.0
species: 183652

199292
type: SpeciesReference
stoichiometry: 1.0
species: 166904

952135
type: Reaction
reactant: 252881
is: ENSMUSG00000042118.6
notes: R_BHMT subsystem: Glycine, Serine, and Threonine Metabolism R_BHMT equation: [c] : glyb + hcys-L --> dmgly + met-L
product: 252893
fast: false
reversible: false
is: http://identifiers.org/ec-code/2.1.1.5
is: ENSMUSG00000066252.2
is: ENSMUSG00000074768.2
reactant: 252869
product: 252905
is: ENSMUSG00000069324.3
name: betaine-homocysteine S-methyltransferase

252881
type: SpeciesReference
stoichiometry: 1.0
species: 174697

252893
type: SpeciesReference
stoichiometry: 1.0
species: 171111

252869
type: SpeciesReference
stoichiometry: 1.0
species: 175926

252905
type: SpeciesReference
stoichiometry: 1.0
species: 180740

952977
type: Reaction
is: ENSMUSG00000031608.6
is: ENSMUSG00000024064.6
is: ENSMUSG00000039774.5
fast: false
is: ENSMUSG00000038072.7
name: GalNAc transferase, Golgi apparatus
reversible: false
reactant: 263427
reactant: 263439
is: ENSMUSG00000033316.7
is: ENSMUSG00000021903.4
is: ENSMUSG00000032323.7
is: http://identifiers.org/ec-code/2.4.1.41
is: ENSMUSG00000020520.7
is: ENSMUSG00000061864.3
product: 263451
is: ENSMUSG00000026994.2
notes: R_GALNTg subsystem: O-Glycan Biosynthesis R_GALNTg equation: [g] : Ser/Thr + udpacgal --> Tn_antigen + h + udp
product: 263475
is: ENSMUSG00000026828.2
product: 263463
is: ENSMUSG00000060988.3
is: ENSMUSG00000037280.5

263427
type: SpeciesReference
stoichiometry: 1.0
species: 187681

263439
type: SpeciesReference
stoichiometry: 1.0
species: 164246

164246
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: protein-linked serine or threonine residue (O-glycosylation site)_XH

263451
type: SpeciesReference
stoichiometry: 1.0
species: 187608

263475
type: SpeciesReference
stoichiometry: 1.0
species: 164318

263463
type: SpeciesReference
stoichiometry: 1.0
species: 175746

185133
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Ribosylnicotinamide_C11H15N2O5

948034
type: Reaction
product: 214054
notes: R_DNAMTSEn subsystem: Selenoamino acid metabolism R_DNAMTSEn equation: [n] : dna + seasmet --> dna5mtc + h + seahcys R_DNAMTn subsystem: Methionine Metabolism R_DNAMTn equation: [n] : amet + dna --> ahcys + dna5mtc + h
product: 214067
reactant: 213993
product: 214030
reactant: 214005
reversible: false
reactant: 214017
fast: false
is: ENSMUSG00000020661.7
is: ENSMUSG00000026723.3
is: http://identifiers.org/ec-code/2.1.1.37
is: ENSMUSG00000037664.5
is: ENSMUSG00000027478.8
product: 214042

214054
type: SpeciesReference
stoichiometry: 1.0
species: 185373

214067
type: SpeciesReference
stoichiometry: 1.0
species: 165761

165761
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: S-Adenosyl-L-homocysteine_C14H20N6O5S

213993
type: SpeciesReference
stoichiometry: 2.0
species: 171233

171233
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: DNA_C10H17O8PR2

214030
type: SpeciesReference
stoichiometry: 2.0
species: 171220

214005
type: SpeciesReference
stoichiometry: 1.0
species: 166183

166183
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: S-Adenosyl-L-methionine_C15H23N6O5S

214017
type: SpeciesReference
stoichiometry: 1.0
species: 185399

185399
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: Se-Adenosylselenomethionine_C15H23N6O5Se

214042
type: SpeciesReference
stoichiometry: 2.0
species: 175782

173437
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1960H3228N20O770P20

180788
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: (R)-Mevalonate_C6H11O4

946844
type: Reaction
product: 204022
reactant: 203902
reversible: false
fast: false
reactant: 203926
reactant: 203950
notes: R_S6T3g subsystem: Keratan sulfate biosynthesis R_S6T3g equation: [g] : ksii_core2_pre10 + paps --> h + ksii_core2 + pap R_S6T24g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T24g equation: [g] : cs_e_pre4 + paps --> cs_e_pre5b + h + pap R_S6T20g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T20g equation: [g] : cs_c_pre3 + paps --> cspg_c + h + pap R_S6T19g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T19g equation: [g] : cs_pre + (2) paps --> cs_c,d,e_pre1 + (2) h + (2) pap R_S6T18g subsystem: Keratan sulfate biosynthesis R_S6T18g equation: [g] : ksii_core4_pre10 + paps --> h + ksii_core4 + pap R_S6T15g subsystem: Keratan sulfate biosynthesis R_S6T15g equation: [g] : ksi_pre36 + paps --> h + ksi + pap R_S6T21g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T21g equation: [g] : cs_d_pre4 + paps --> cs_d_pre5 + h + pap
product: 203998
reactant: 203962
reactant: 203974
product: 204046
product: 204034
product: 204082
product: 204070
product: 204010
product: 204058
product: 204094
is: ENSMUSG00000057337.5
reactant: 203938
reactant: 203986
reactant: 203914
is: http://identifiers.org/ec-code/2.8.2.17

204022
type: SpeciesReference
stoichiometry: 1.0
species: 169577

203902
type: SpeciesReference
stoichiometry: 1.0
species: 178882

178882
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 10_C89H143N7O69S2X

203926
type: SpeciesReference
stoichiometry: 1.0
species: 169212

203950
type: SpeciesReference
stoichiometry: 1.0
species: 169516

203998
type: SpeciesReference
stoichiometry: 1.0
species: 178099

178099
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I_C247H393N17O213S12X

203962
type: SpeciesReference
stoichiometry: 1.0
species: 169479

203974
type: SpeciesReference
stoichiometry: 1.0
species: 178461

178461
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 36_C247H394N17O210S11X

204046
type: SpeciesReference
stoichiometry: 1.0
species: 169345

169345
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 5_C45H65N2O48S4X

204034
type: SpeciesReference
stoichiometry: 8.0
species: 175746

204082
type: SpeciesReference
stoichiometry: 1.0
species: 178858

204070
type: SpeciesReference
stoichiometry: 1.0
species: 178666

204010
type: SpeciesReference
stoichiometry: 1.0
species: 169115

204058
type: SpeciesReference
stoichiometry: 8.0
species: 183120

204094
type: SpeciesReference
stoichiometry: 1.0
species: 169503

203938
type: SpeciesReference
stoichiometry: 8.0
species: 183143

203986
type: SpeciesReference
stoichiometry: 1.0
species: 178690

178690
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 10_C81H130N6O64S2X

203914
type: SpeciesReference
stoichiometry: 1.0
species: 169333

952929
type: Reaction
fast: false
product: 263001
reactant: 262965
is: ENSMUSG00000026856.7
reactant: 262977
product: 263013
reactant: 262989
notes: R_DOLDPP_Ler subsystem: N-Glycan Biosynthesis R_DOLDPP_Ler equation: [r] : (0.1) doldp_L + h2o --> (0.1) dolp_L + h + pi R_DOLDPP_Uer subsystem: N-Glycan Biosynthesis R_DOLDPP_Uer equation: [r] : (0.1) doldp_U + h2o --> (0.1) dolp_U + h + pi
product: 263038
is: http://identifiers.org/ec-code/3.6.1.43
reversible: false
product: 263026

263001
type: SpeciesReference
stoichiometry: 1.0
species: 171415

262965
type: SpeciesReference
stoichiometry: 1.0
species: 171282

171282
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Dolichol diphosphate, human liver homolog_C1080H1758O70P20

262977
type: SpeciesReference
stoichiometry: 2.0
species: 175686

263013
type: SpeciesReference
stoichiometry: 2.0
species: 183724

262989
type: SpeciesReference
stoichiometry: 1.0
species: 171294

171294
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: Dolichol diphosphate, human uterine homolog_C1025H1670O70P20

263038
type: SpeciesReference
stoichiometry: 2.0
species: 175794

263026
type: SpeciesReference
stoichiometry: 1.0
species: 171439

179883
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: L-Lysine_C6H15N2O2

953745
type: Reaction
product: 269652
product: 269688
reactant: 269628
product: 269664
fast: false
reversible: true
reactant: 269603
reactant: 269567
reactant: 269616
product: 269700
reactant: 269591
product: 269640
product: 269676
is: ENSMUSG00000031170.7
notes: R_GLNtN1 subsystem: Transport, Extracellular R_GLNtN1 equation: gln-L[e] + h[c] + (2) na1[e] <==> gln-L[c] + h[e] + (2) na1[c] R_SERtN1 subsystem: Transport, Extracellular R_SERtN1 equation: h[c] + (2) na1[e] + ser-L[e] <==> h[e] + (2) na1[c] + ser-L[c] R_ASNtN1 subsystem: Transport, Extracellular R_ASNtN1 equation: asn-L[e] + h[c] + (2) na1[e] <==> asn-L[c] + h[e] + (2) na1[c] R_ALAtN1 subsystem: Transport, Extracellular R_ALAtN1 equation: ala-L[e] + h[c] + (2) na1[e] <==> ala-L[c] + h[e] + (2) na1[c]
reactant: 269579

269652
type: SpeciesReference
stoichiometry: 1.0
species: 185532

269688
type: SpeciesReference
stoichiometry: 1.0
species: 166796

269628
type: SpeciesReference
stoichiometry: 4.0
species: 175722

269664
type: SpeciesReference
stoichiometry: 1.0
species: 174382

269603
type: SpeciesReference
stoichiometry: 1.0
species: 174394

269567
type: SpeciesReference
stoichiometry: 1.0
species: 166027

269616
type: SpeciesReference
stoichiometry: 1.0
species: 185544

269700
type: SpeciesReference
stoichiometry: 1.0
species: 166015

269591
type: SpeciesReference
stoichiometry: 8.0
species: 181389

269640
type: SpeciesReference
stoichiometry: 4.0
species: 175734

269676
type: SpeciesReference
stoichiometry: 8.0
species: 181377

269579
type: SpeciesReference
stoichiometry: 1.0
species: 166808

170943
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Digalactosylceramide_C30H56NO12FULLRCO

949741
type: Reaction
reactant: 229325
reactant: 229301
name: GDP-L-fucose synthase
fast: false
product: 229349
is: ENSMUSG00000022570.4
notes: R_GFUCS subsystem: Fructose and Mannose Metabolism R_GFUCS equation: [c] : gdpddman + h + nadph --> gdpfuc + nadp
reactant: 229313
product: 229337
is: http://identifiers.org/ec-code/1.1.1.271
reversible: false

229325
type: SpeciesReference
stoichiometry: 1.0
species: 181631

229301
type: SpeciesReference
stoichiometry: 1.0
species: 174178

174178
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514

229349
type: SpeciesReference
stoichiometry: 1.0
species: 181558

229313
type: SpeciesReference
stoichiometry: 1.0
species: 175722

229337
type: SpeciesReference
stoichiometry: 1.0
species: 174190

174190
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: GDP-L-fucose_C16H23N5O15P2

W3 CDTF: Thu Aug 12 17:07:45 BST 2010

947660
type: Reaction
reactant: 211392
notes: R_SERPT subsystem: Sphingolipid Metabolism R_SERPT equation: [c] : h + pmtcoa + ser-L --> 3dsphgn + co2 + coa
name: serine C-palmitoyltransferase
product: 211452
is: http://identifiers.org/ec-code/2.3.1.50
is: ENSMUSG00000021036.3
fast: false
is: ENSMUSG00000021468.5
reactant: 211404
product: 211440
reversible: false
product: 211428
reactant: 211416

211392
type: SpeciesReference
stoichiometry: 1.0
species: 185532

211452
type: SpeciesReference
stoichiometry: 1.0
species: 161794

161794
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Dehydrosphinganine_C18H38NO2

211404
type: SpeciesReference
stoichiometry: 1.0
species: 183748

211440
type: SpeciesReference
stoichiometry: 1.0
species: 168436

211428
type: SpeciesReference
stoichiometry: 1.0
species: 168509

211416
type: SpeciesReference
stoichiometry: 1.0
species: 175722

185097
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: retinoyl glucuronide_C26H35O8

176734
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 8_C69H100N4O81S8

954561
type: Reaction
is: ENSMUSG00000025003.3
is: ENSMUSG00000030483.7
reactant: 277580
is: ENSMUSG00000068083.1
is: ENSMUSG00000025197.7
is: ENSMUSG00000032808.2
is: ENSMUSG00000074254.2
is: ENSMUSG00000060613.3
product: 277689
is: ENSMUSG00000040660.5
is: ENSMUSG00000025004.5
product: 277665
is: ENSMUSG00000042248.2
is: ENSMUSG00000067231.3
reactant: 277605
is: ENSMUSG00000025479.6
is: ENSMUSG00000040650.7
reactant: 277617
is: ENSMUSG00000058613.3
is: ENSMUSG00000067225.1
reactant: 277556
is: ENSMUSG00000074882.2
reactant: 277532
reversible: false
product: 277653
reactant: 277568
product: 277641
is: ENSMUSG00000067229.2
reactant: 277544
fast: false
is: ENSMUSG00000054827.5
is: ENSMUSG00000066704.4
is: ENSMUSG00000040583.6
product: 277677
is: ENSMUSG00000003053.7
notes: R_P4502F1 subsystem: CYP Metabolism R_P4502F1 equation: [c] : h + nadph + npthl + o2 --> h2o + nadp + onpthl R_P4504B1r subsystem: Eicosanoid Metabolism R_P4504B1r equation: [r] : arachd + h + nadph + o2 --> 12harachd + h2o + nadp
is: http://identifiers.org/ec-code/1.14.14.1
is: ENSMUSG00000062624.4
reactant: 277592
product: 277629

277580
type: SpeciesReference
stoichiometry: 1.0
species: 175794

277689
type: SpeciesReference
stoichiometry: 1.0
species: 175614

277665
type: SpeciesReference
stoichiometry: 1.0
species: 181558

277605
type: SpeciesReference
stoichiometry: 1.0
species: 175722

277617
type: SpeciesReference
stoichiometry: 1.0
species: 181631

277556
type: SpeciesReference
stoichiometry: 1.0
species: 181996

277532
type: SpeciesReference
stoichiometry: 1.0
species: 182202

277653
type: SpeciesReference
stoichiometry: 1.0
species: 160883

160883
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _12 hydroxy arachidonic acid_C20H31O3

277568
type: SpeciesReference
stoichiometry: 1.0
species: 166640

166640
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: arachidonic acid_C20H31O2

277641
type: SpeciesReference
stoichiometry: 1.0
species: 175686

277544
type: SpeciesReference
stoichiometry: 1.0
species: 181667

277677
type: SpeciesReference
stoichiometry: 1.0
species: 181607

277592
type: SpeciesReference
stoichiometry: 1.0
species: 182154

277629
type: SpeciesReference
stoichiometry: 1.0
species: 182635

182635
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: naphthalene epoxide_C10H8O

188694
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Xylulose 1-phosphate_C5H9O8P

181825
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Nicotinate D-ribonucleoside_C11H13NO6

184567
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Propenoyl-CoA_C24H34N7O17P3S

163511
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: _6-Pyruvoyl-5,6,7,8-tetrahydropterin_C9H11N5O3

174491
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: L-Glutamate_C5H8NO4

160980
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _15-Hydroperoxyeicosatetraenoic acid_C20H31O4

946302
type: Reaction
product: 198712
fast: false
is: ENSMUSG00000027130.6
reversible: true
is: ENSMUSG00000017765.7
product: 198700
notes: R_KCC2t subsystem: Transport, Extracellular R_KCC2t equation: cl[e] + nh4[e] <==> cl[c] + nh4[c] R_KCCt subsystem: Transport, Extracellular R_KCCt equation: cl[e] + k[e] <==> cl[c] + k[c]
product: 198724
reactant: 198688
reactant: 198675
is: ENSMUSG00000017756.6
reactant: 198662

198712
type: SpeciesReference
stoichiometry: 2.0
species: 168196

198700
type: SpeciesReference
stoichiometry: 1.0
species: 177531

198724
type: SpeciesReference
stoichiometry: 1.0
species: 181752

198688
type: SpeciesReference
stoichiometry: 2.0
species: 168208

198675
type: SpeciesReference
stoichiometry: 1.0
species: 181764

198662
type: SpeciesReference
stoichiometry: 1.0
species: 177543

948899
type: Reaction
reactant: 221258
product: 221366
reversible: false
fast: false
reactant: 221282
product: 221390
product: 221378
reactant: 221306
reactant: 221270
reactant: 221294
product: 221342
product: 221330
product: 221318
is: ENSMUSG00000031604.3
reactant: 221246
notes: R_C4STMO1r subsystem: Cholesterol Metabolism R_C4STMO1r equation: [r] : 44mzym + (3) h + (3) nadph + (3) o2 --> 4mzym_int1 + (4) h2o + (3) nadp R_C4STMO2r subsystem: Cholesterol Metabolism R_C4STMO2r equation: [r] : 4mzym_int2 + nad + o2 --> co2 + h + nadh + zym_int2
product: 221354

221258
type: SpeciesReference
stoichiometry: 4.0
species: 182202

221366
type: SpeciesReference
stoichiometry: 3.0
species: 181607

221282
type: SpeciesReference
stoichiometry: 1.0
species: 162725

162725
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _4-Methylzymosterol intermediate 2_C28H44O

221390
type: SpeciesReference
stoichiometry: 1.0
species: 162713

162713
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _4-Methylzymosterol intermediate 1_C29H46O3

221378
type: SpeciesReference
stoichiometry: 1.0
species: 175794

221306
type: SpeciesReference
stoichiometry: 3.0
species: 175794

221270
type: SpeciesReference
stoichiometry: 3.0
species: 181667

221294
type: SpeciesReference
stoichiometry: 1.0
species: 181486

221342
type: SpeciesReference
stoichiometry: 1.0
species: 181534

221330
type: SpeciesReference
stoichiometry: 1.0
species: 188778

221318
type: SpeciesReference
stoichiometry: 1.0
species: 168473

221246
type: SpeciesReference
stoichiometry: 1.0
species: 162386

162386
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160526
name: _4,4-dimethylzymosterol_C29H48O

221354
type: SpeciesReference
stoichiometry: 4.0
species: 175686

947228
type: Reaction
reactant: 207827
is: ENSMUSG00000038843.7
reactant: 207840
notes: R_CORE2GTg subsystem: O-Glycan Biosynthesis R_CORE2GTg equation: [g] : T_antigen + uacgam --> core2 + h + udp R_CORE6GTg subsystem: O-Glycan Biosynthesis R_CORE6GTg equation: [g] : Tn_antigen + uacgam --> core6 + h + udp
product: 207876
product: 207852
reactant: 207815
reversible: false
fast: false
product: 207888
product: 207864
is: http://identifiers.org/ec-code/2.4.1.102

207827
type: SpeciesReference
stoichiometry: 1.0
species: 164306

207840
type: SpeciesReference
stoichiometry: 1.0
species: 164318

207876
type: SpeciesReference
stoichiometry: 1.0
species: 168641

168641
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: Core 6_C16H27N2O10X

207852
type: SpeciesReference
stoichiometry: 2.0
species: 187608

207815
type: SpeciesReference
stoichiometry: 2.0
species: 187572

207888
type: SpeciesReference
stoichiometry: 1.0
species: 168605

207864
type: SpeciesReference
stoichiometry: 2.0
species: 175746

178027
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 5_C222H356N15O194S11

170085
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: dCMP_C9H12N3O7P

946470
type: Reaction
notes: R_HEXCCPT2 subsystem: Carnitine shuttle R_HEXCCPT2 equation: [m] : coa + hexccrn --> crn + hexccoa R_C181CPT2 subsystem: Carnitine shuttle R_C181CPT2 equation: [m] : coa + odecrn --> crn + odecoa R_C160CPT2 subsystem: Carnitine shuttle R_C160CPT2 equation: [m] : coa + pmtcrn --> crn + pmtcoa R_RTOTALCRNCPT2 subsystem: Carnitine shuttle R_RTOTALCRNCPT2 equation: [m] : Rtotalcrn + coa --> Rtotalcoa + crn R_RTOTAL2CRNCPT2 subsystem: Carnitine shuttle R_RTOTAL2CRNCPT2 equation: [m] : Rtotal2crn + coa --> Rtotal2coa + crn R_VACCCPT2 subsystem: Carnitine shuttle R_VACCCPT2 equation: [m] : coa + vacccrn --> crn + vacccoa R_EICOSTETCPT2 subsystem: Carnitine shuttle R_EICOSTETCPT2 equation: [m] : coa + eicostetcrn --> crn + eicostetcoa R_TTDCPT2 subsystem: Carnitine shuttle R_TTDCPT2 equation: [m] : coa + ttdcrn --> crn + tdcoa R_PTDCACRNCPT2 subsystem: Carnitine shuttle R_PTDCACRNCPT2 equation: [m] : coa + ptdcacrn --> crn + ptdcacoa R_LGNCCPT2 subsystem: Carnitine shuttle R_LGNCCPT2 equation: [m] : coa + lgnccrn --> crn + lgnccoa R_C226CPT2 subsystem: Carnitine shuttle R_C226CPT2 equation: [m] : c226crn + coa --> c226coa + crn R_C161CPT22 subsystem: Carnitine shuttle R_C161CPT22 equation: [m] : coa + hdd2crn --> crn + hdd2coa R_DLNLCGCPT2 subsystem: Carnitine shuttle R_DLNLCGCPT2 equation: [m] : coa + dlnlcgcrn --> crn + dlnlcgcoa R_LNLCCPT2 subsystem: Carnitine shuttle R_LNLCCPT2 equation: [m] : coa + lnlccrn --> crn + lnlccoa R_CLPNDCPT2 subsystem: Carnitine shuttle R_CLPNDCPT2 equation: [m] : clpndcrn + coa --> clpndcoa + crn R_DCSPTN1CPT2 subsystem: Carnitine shuttle R_DCSPTN1CPT2 equation: [m] : coa + dcsptn1crn --> crn + dcsptn1coa R_HPDCACRNCPT2 subsystem: Carnitine shuttle R_HPDCACRNCPT2 equation: [m] : coa + hpdcacrn --> crn + hpdcacoa R_LNELDCCPT2 subsystem: Carnitine shuttle R_LNELDCCPT2 equation: [m] : coa + lneldccrn --> crn + lneldccoa R_STRDNCCPT2 subsystem: Carnitine shuttle R_STRDNCCPT2 equation: [m] : coa + strdnccrn --> crn + strdnccoa R_NRVNCCPT2 subsys…
reactant: 200052
reactant: 200208
reactant: 200220
reactant: 200040
product: 200583
product: 200547
product: 200693
product: 200596
reactant: 200148
reactant: 199968
reactant: 199980
product: 200657
reactant: 200292
fast: false
reactant: 200136
reactant: 199956
reactant: 200280
is: ENSMUSG00000028607.7
product: 200365
product: 200462
product: 200426
product: 200571
product: 200535
reactant: 200124
reactant: 200196
reactant: 199944
product: 200681
product: 200645
reactant: 199932
reactant: 200112
reversible: false
product: 200328
reactant: 200028
reactant: 200316
product: 200340
product: 200559
product: 200401
product: 200450
product: 200414
reactant: 200184
product: 200669
product: 200511
reactant: 200100
reactant: 200172
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200208
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164114
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200220
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170169
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200547
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200693
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200596
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200148
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179449
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199980
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200657
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200292
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200136
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186513
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187146
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200280
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186658
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200462
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182082
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200426
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200571
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200535
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176156
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200124
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200196
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199944
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200681
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200645
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164186
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199932
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200112
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200328
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200028
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200316
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176096
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200340
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200559
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200401
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200450
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200414
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200184
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166700
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200669
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164016
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200511
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200100
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200172
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184687
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199920
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164222
type: Species
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200268
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171087
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200621
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200016
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200088
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200705
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200377
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200004
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200718
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200389
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200474
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200438
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200487
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200499
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200160
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187476
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200608
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164089
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200256
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200076
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182118
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200244
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186586
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200064
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168292
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200730
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168256
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200353
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species: 182527

200304
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species: 188188

188188
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200523
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199992
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172065
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200232
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200633
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species: 176397

188586
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948262
type: Reaction
product: 216315
reactant: 216291
reversible: true
is: http://identifiers.org/ec-code/2.7.7.30
notes: R_F1PGT subsystem: Fructose and Mannose Metabolism R_F1PGT equation: [c] : fuc1p-L + gtp + h <==> gdpfuc + ppi
fast: false
product: 216327
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reactant: 216279
name: fucose-1-phosphate guanylyltransferase
reactant: 216303

216315
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species: 174190

216291
type: SpeciesReference
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species: 175434

216327
type: SpeciesReference
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species: 183917

216279
type: SpeciesReference
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species: 173004

173004
type: Species
constant: false
boundary condition: false
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initial concentration: NaN
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in compartment: 160514
name: L-Fucose 1-phosphate_C6H11O8P

216303
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species: 175722

186864
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boundary condition: false
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name: Thiamin monophosphate_C12H16N4O4PS

950486
type: Reaction
notes: R_GALT subsystem: Galactose metabolism R_GALT equation: [c] : gal1p + h + utp <==> ppi + udpgal R_UGLT subsystem: Galactose metabolism R_UGLT equation: [c] : gal1p + udpg <==> g1p + udpgal
is: http://identifiers.org/ec-code/2.7.7.10
reactant: 237806
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product: 237854
reactant: 237830
reactant: 237794
product: 237842
reversible: true
product: 237867
reactant: 237818
is: http://identifiers.org/ec-code/2.7.7.12
is: ENSMUSG00000036073.8

237806
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species: 173570

237854
type: SpeciesReference
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species: 173377

237830
type: SpeciesReference
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species: 188092

237794
type: SpeciesReference
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species: 187717

237842
type: SpeciesReference
stoichiometry: 2.0
species: 187753

237867
type: SpeciesReference
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species: 183917

237818
type: SpeciesReference
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species: 175722

169565
type: Species
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initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S) proteoglycan_C45H65N2O48S4X

168172
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initial amount: NaN
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name: L-Citrulline_C6H13N3O3

162871
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name: _5,6-dihydrouracil_C4H6N2O2

175082
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initial concentration: NaN
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in compartment: 160550
name: GP1c alpha (homo sapiens)_C99H159N7O62FULLRCO

163257
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950762
type: Reaction
reactant: 239662
name: phosphate transport in/out via Na+ symporter
reversible: true
notes: R_PIt8 subsystem: Transport, Extracellular R_PIt8 equation: (1.5) na1[e] + pi[e] <==> (1.5) na1[c] + pi[c]
reactant: 239650
fast: false
is: ENSMUSG00000037656.7
is: ENSMUSG00000027397.5
product: 239687
product: 239675

239662
type: SpeciesReference
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species: 183664

239650
type: SpeciesReference
stoichiometry: 1.5
species: 181389

239687
type: SpeciesReference
stoichiometry: 1.5
species: 181377

239675
type: SpeciesReference
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species: 183652

165835
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _1-alkyl 2-lysoglycerol 3-phosphocholine_C10H21O5NPFULLR

945794
type: Reaction
reactant: 194527
name: choline phosphotransferase
fast: false
notes: R_CEPTC subsystem: Glycerophospholipid Metabolism R_CEPTC equation: [c] : cdpchol + dag_hs --> cmp + h + pchol_hs
reactant: 194539
product: 194575
is: ENSMUSG00000060002.5
product: 194563
product: 194551
reversible: false

194527
type: SpeciesReference
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species: 169878

194539
type: SpeciesReference
stoichiometry: 1.0
species: 167687

194575
type: SpeciesReference
stoichiometry: 1.0
species: 175722

194563
type: SpeciesReference
stoichiometry: 1.0
species: 183155

194551
type: SpeciesReference
stoichiometry: 1.0
species: 168316

951173
type: Reaction
notes: R_IPDDIx subsystem: Cholesterol Metabolism R_IPDDIx equation: [x] : ipdp <==> dmpp
is: ENSMUSG00000021148.4
is: http://identifiers.org/ec-code/5.3.3.2
name: isopentenyl-diphosphate D-isomerase
is: ENSMUSG00000033520.1
is: ENSMUSG00000058258.5
fast: false
product: 244164
reversible: true
reactant: 244152

244164
type: SpeciesReference
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species: 171208

244152
type: SpeciesReference
stoichiometry: 1.0
species: 177447

180885
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: _1D-myo-Inositol 1,3,4,6-tetrakisphosphate_C6H8O18P4

953481
type: Reaction
product: 267349
product: 267373
reactant: 267325
product: 267337
product: 267361
product: 267409
reversible: true
reactant: 267277
reactant: 267313
reactant: 267289
reactant: 267301
notes: R_S4TASE2ly subsystem: Chondroitin sulfate degradation R_S4TASE2ly equation: [l] : cs_a_deg3 + h2o <==> cs_a_deg4 + h + so4 R_S4TASE3ly subsystem: Chondroitin sulfate degradation R_S4TASE3ly equation: [l] : cs_b + h2o <==> cs_b_deg1 + h + so4 R_S4TASE1ly subsystem: Chondroitin sulfate degradation R_S4TASE1ly equation: [l] : cs_a + h2o <==> cs_a_deg1 + h + so4 R_S4TASE5ly subsystem: Chondroitin sulfate degradation R_S4TASE5ly equation: [l] : cs_e_deg4 + h2o <==> cs_e_deg5 + h + so4 R_S4TASE4ly subsystem: Chondroitin sulfate degradation R_S4TASE4ly equation: [l] : cs_e + h2o <==> cs_e_deg1 + h + so4
fast: false
reactant: 267265
is: ENSMUSG00000042082.4
is: http://identifiers.org/ec-code/3.1.6.12
product: 267397
product: 267385

267349
type: SpeciesReference
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species: 169043

267373
type: SpeciesReference
stoichiometry: 5.0
species: 175758

267325
type: SpeciesReference
stoichiometry: 1.0
species: 169443

169443
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), free chain_C45H64N2O55S6

267337
type: SpeciesReference
stoichiometry: 1.0
species: 169007

267361
type: SpeciesReference
stoichiometry: 5.0
species: 185679

267409
type: SpeciesReference
stoichiometry: 1.0
species: 168971

168971
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 1_C45H68N2O43S2

267277
type: SpeciesReference
stoichiometry: 1.0
species: 169393

267313
type: SpeciesReference
stoichiometry: 1.0
species: 168995

168995
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 3_C31H48NO32S2

267289
type: SpeciesReference
stoichiometry: 1.0
species: 169079

169079
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), free chain_C45H66N2O49S4

267301
type: SpeciesReference
stoichiometry: 5.0
species: 175650

267265
type: SpeciesReference
stoichiometry: 1.0
species: 169031

169031
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate A (GalNAc4S-GlcA), free chain_C45H67N2O46S3

267397
type: SpeciesReference
stoichiometry: 1.0
species: 169357

267385
type: SpeciesReference
stoichiometry: 1.0
species: 169405

169405
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 5_C31H47NO35S3

179267
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Leukotriene A4_C20H29O3

953589
type: Reaction
modifier: 268147
modifier: 268135
is: ENSMUSG00000025465.5
fast: false
modifier: 268183
modifier: 268171
reactant: 268110
modifier: 268196
notes: R_ECOAH12m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ECOAH12m equation: [m] : 2mp2coa + h2o <==> 3hibutcoa R_PRPNCOAHYDm subsystem: beta-Alanine metabolism R_PRPNCOAHYDm equation: [m] : h2o + prpncoa --> 3hpcoa R_ECOAH9m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ECOAH9m equation: [m] : 2mb2coa + h2o <==> 3hmbcoa R_ECOAH1m subsystem: Tryptophan metabolism R_ECOAH1m equation: [m] : 3hbcoa <==> b2coa + h2o
modifier: 268208
reactant: 268098
is: http://identifiers.org/ec-code/4.2.1.17
product: 268123
modifier: 268159
reversible: false

161879
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574

268110
type: SpeciesReference
stoichiometry: 1.0
species: 184555

268098
type: SpeciesReference
stoichiometry: 1.0
species: 175662

268123
type: SpeciesReference
stoichiometry: 1.0
species: 161927

947072
type: Reaction
reactant: 206014
reactant: 206051
reactant: 206100
product: 206269
product: 206256
fast: false
product: 206343
reactant: 206124
reactant: 206039
is: ENSMUSG00000047379.6
product: 206355
is: ENSMUSG00000079445.1
reversible: false
reactant: 206088
product: 206172
product: 206281
product: 206208
product: 206184
product: 206307
product: 206391
product: 206319
reactant: 205954
reactant: 205978
reactant: 206112
product: 206220
reactant: 206136
product: 206232
is: http://identifiers.org/ec-code/2.4.1.149
product: 206160
is: ENSMUSG00000059479.5
product: 206331
reactant: 205930
reactant: 206075
reactant: 206002
product: 206294
reactant: 205966
reactant: 206063
reactant: 206027
notes: R_AG13T6g subsystem: Keratan sulfate biosynthesis R_AG13T6g equation: [g] : ksi_pre6 + uacgam --> h + ksi_pre7 + udp R_AG13T17g subsystem: Keratan sulfate biosynthesis R_AG13T17g equation: [g] : ksii_core4_pre4 + uacgam --> h + ksii_core4_pre5 + udp R_AG13T2g subsystem: Keratan sulfate biosynthesis R_AG13T2g equation: [g] : ksii_core2_pre4 + uacgam --> h + ksii_core2_pre5 + udp R_AG13T5g subsystem: Keratan sulfate biosynthesis R_AG13T5g equation: [g] : ksi_pre3 + uacgam --> h + ksi_pre4 + udp R_AG13T8g subsystem: Keratan sulfate biosynthesis R_AG13T8g equation: [g] : ksi_pre12 + uacgam --> h + ksi_pre13 + udp R_AG13T12g subsystem: Keratan sulfate biosynthesis R_AG13T12g equation: [g] : ksi_pre24 + uacgam --> h + ksi_pre25 + udp R_AG13T1g subsystem: Keratan sulfate biosynthesis R_AG13T1g equation: [g] : ksii_core2_pre2 + uacgam --> h + ksii_core2_pre3 + udp R_AG13T10g subsystem: Keratan sulfate biosynthesis R_AG13T10g equation: [g] : ksi_pre18 + uacgam --> h + ksi_pre19 + udp R_AG13T14g subsystem: Keratan sulfate biosynthesis R_AG13T14g equation: [g] : ksi_pre30 + uacgam --> h + ksi_pre31 + udp R_AG13T13g subsystem: Keratan sulfate biosynthesis R_AG13T13g equation: [g] : ksi_pre27 + uacgam --> h + ksi_pre28 + udp R_AG13T9g subsystem: Keratan sulfate biosynthesis R_AG13T9g equation: [g] : ksi_pre15 + uacgam --> h + ksi_pre16 + udp R_AG13T15g subsystem: Keratan sulfate biosynthesis R_AG13T15g equation: [g] : ksi_pre33 + uacgam --> h + ksi_pre34 + udp R_AG13T4g subsystem: Keratan sulfate biosynthesis R_AG13T4g equation: [g] : ksi_pre1 + uacgam --> h + ksi_pre2 + udp R_AG13T11g subsystem: Keratan sulfate biosynthesis R_AG13T11g equation: [g] : ksi_pre21 + uacgam --> h + ksi_pre22 + udp R_AG13T16g subsystem: Keratan sulfate biosynthesis R_AG13T16g equation: [g] : ksii_core4_pre2 + uacgam --> h + ksii_core4_pre3 + udp R_AG13T18g subsystem: Keratan sulfate biosynthesis R_AG13T18g equation: [g] : ksii_core4_pre7 + uacgam --> h + ksii_core4_pre8 + udp R_AG13T7g subsystem: Ker…
reactant: 205990
product: 206244
reactant: 205942
product: 206196
is: ENSMUSG00000029431.4
product: 206367
reactant: 206148
product: 206379
is: ENSMUSG00000046605.7

206014
type: SpeciesReference
stoichiometry: 18.0
species: 187572

206051
type: SpeciesReference
stoichiometry: 1.0
species: 178220

178220
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 18_C163H262N11O132S5X

206100
type: SpeciesReference
stoichiometry: 1.0
species: 178906

178906
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II boisynthesis, precursor 2_C47H76N4O33X

206269
type: SpeciesReference
stoichiometry: 1.0
species: 178750

178750
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 5_C61H99N5O43X

206256
type: SpeciesReference
stoichiometry: 1.0
species: 178123

178123
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 10_C129H209N9O98S2X

206343
type: SpeciesReference
stoichiometry: 1.0
species: 178485

178485
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 4_C101H165N7O72X

206124
type: SpeciesReference
stoichiometry: 1.0
species: 178738

178738
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 4_C53H86N4O38X

206039
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stoichiometry: 1.0
species: 178545

178545
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 9_C121H196N8O93S2X

206355
type: SpeciesReference
stoichiometry: 1.0
species: 178942

178942
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 5_C69H112N6O48X

206088
type: SpeciesReference
stoichiometry: 1.0
species: 178714

206172
type: SpeciesReference
stoichiometry: 1.0
species: 178317

206281
type: SpeciesReference
stoichiometry: 1.0
species: 178786

178786
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 8_C75H121N6O56SX

206208
type: SpeciesReference
stoichiometry: 1.0
species: 178353

178353
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 28_C213H341N15O176S8X

206184
type: SpeciesReference
stoichiometry: 1.0
species: 178978

178978
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 8_C83H134N7O61SX

206307
type: SpeciesReference
stoichiometry: 1.0
species: 178377

206391
type: SpeciesReference
stoichiometry: 1.0
species: 178232

206319
type: SpeciesReference
stoichiometry: 1.0
species: 178726

178726
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 3_C47H76N4O33X

205954
type: SpeciesReference
stoichiometry: 1.0
species: 178473

205978
type: SpeciesReference
stoichiometry: 1.0
species: 178305

178305
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 24_C191H306N13O158S7X

206112
type: SpeciesReference
stoichiometry: 1.0
species: 178930

178930
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 4_C61H99N5O43X

206220
type: SpeciesReference
stoichiometry: 18.0
species: 187608

206136
type: SpeciesReference
stoichiometry: 1.0
species: 178509

206232
type: SpeciesReference
stoichiometry: 1.0
species: 178521

206160
type: SpeciesReference
stoichiometry: 1.0
species: 178918

206331
type: SpeciesReference
stoichiometry: 1.0
species: 178160

178160
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 13_C143H231N10O111S3X

205930
type: SpeciesReference
stoichiometry: 1.0
species: 178389

178389
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 30_C219H350N15O184S9X

206075
type: SpeciesReference
stoichiometry: 1.0
species: 178184

178184
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 15_C149H240N10O119S4X

206002
type: SpeciesReference
stoichiometry: 1.0
species: 178244

206294
type: SpeciesReference
stoichiometry: 1.0
species: 178281

178281
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 22_C185H297N13O150S6X

205966
type: SpeciesReference
stoichiometry: 1.0
species: 178966

206063
type: SpeciesReference
stoichiometry: 1.0
species: 178774

178774
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate II biosynthesis, precursor 7_C67H108N5O51SX

206027
type: SpeciesReference
stoichiometry: 1.0
species: 178425

205990
type: SpeciesReference
stoichiometry: 1.0
species: 178148

178148
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 12_C135H218N9O106S3X

206244
type: SpeciesReference
stoichiometry: 18.0
species: 175746

205942
type: SpeciesReference
stoichiometry: 1.0
species: 178341

178341
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 27_C205H328N14O171S8X

206196
type: SpeciesReference
stoichiometry: 1.0
species: 178401

178401
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 31_C227H363N16O189S9X

206367
type: SpeciesReference
stoichiometry: 1.0
species: 178437

178437
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 34_C241H385N17O202S10X

206148
type: SpeciesReference
stoichiometry: 1.0
species: 178269

206379
type: SpeciesReference
stoichiometry: 1.0
species: 178196

178196
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: keratan sulfate I biosynthesis, precursor 16_C157H253N11O124S4X

184771
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Pyridoxal_C8H9NO3

949945
type: Reaction
notes: R_FACOAL40im subsystem: Fatty acid activation R_FACOAL40im equation: [m] : atp + but + coa --> amp + btcoa + ppi
fast: false
reactant: 231261
is: ENSMUSG00000033533.5
name: fatty-acid--CoA ligase (butanoate), mitochondrial
reactant: 231249
reversible: false
product: 231286
reactant: 231237
product: 231273
product: 231298
is: http://identifiers.org/ec-code/6.2.1.2
is: ENSMUSG00000047026.7

231261
type: SpeciesReference
stoichiometry: 1.0
species: 166928

231249
type: SpeciesReference
stoichiometry: 1.0
species: 168545

231286
type: SpeciesReference
stoichiometry: 1.0
species: 167266

231237
type: SpeciesReference
stoichiometry: 1.0
species: 167351

231273
type: SpeciesReference
stoichiometry: 1.0
species: 166267

231298
type: SpeciesReference
stoichiometry: 1.0
species: 183929

952531
type: Reaction
modifier: 258507
product: 258300
modifier: 258324
modifier: 258445
modifier: 258543
modifier: 258494
modifier: 258409
is: ENSMUSG00000024891.4
notes: R_ADNt subsystem: Transport, Extracellular R_ADNt equation: adn[e] <==> adn[c] R_INSt subsystem: Transport, Extracellular R_INSt equation: ins[e] <==> ins[c] R_HYXNt subsystem: Transport, Extracellular R_HYXNt equation: hxan[e] <==> hxan[c] R_URIt subsystem: Transport, Extracellular R_URIt equation: uri[e] <==> uri[c] R_GSNt subsystem: Transport, Extracellular R_GSNt equation: gsn[e] <==> gsn[c] R_CSNt subsystem: Transport, Extracellular R_CSNt equation: csn[e] <==> csn[c] R_URAt subsystem: Transport, Extracellular R_URAt equation: ura[e] <==> ura[c] R_ADEt subsystem: Transport, Extracellular R_ADEt equation: ade[e] <==> ade[c] R_GUAt subsystem: Transport, Extracellular R_GUAt equation: gua[e] <==> gua[c] R_THYMt subsystem: Transport, Extracellular R_THYMt equation: thym[e] <==> thym[c] R_THYMDt1 subsystem: Transport, Extracellular R_THYMDt1 equation: thymd[e] --> thymd[c] R_CYTDt subsystem: Transport, Extracellular R_CYTDt equation: cytd[e] <==> cytd[c]
modifier: 258433
modifier: 258348
modifier: 258469
modifier: 258567
fast: false
reactant: 258288
modifier: 258457
modifier: 258372
modifier: 258481
modifier: 258360
modifier: 258531
modifier: 258519
modifier: 258421
modifier: 258312
modifier: 258397
modifier: 258384
modifier: 258555
modifier: 258336
reversible: false

258300
type: SpeciesReference
stoichiometry: 1.0
species: 186984

186972
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Thymine_C5H6N2O2

187960
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Uracil_C4H4N2O2

169541
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Cytosine_C4H5N3O

258288
type: SpeciesReference
stoichiometry: 1.0
species: 186996

186996
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Thymidine_C10H14N2O5

169756
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Cytidine_C9H13N3O5

169528
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Cytosine_C4H5N3O

175482
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Guanine_C5H5N5O

175494
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Guanine_C5H5N5O

173740
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: (Gal)6 (Glc)1 (GlcNAc)3 (LFuc)2 (Cer)1_C96H165N4O60FULLRCO

948947
type: Reaction
is: http://identifiers.org/ec-code/3.1.4.17
is: ENSMUSG00000026239.7
is: ENSMUSG00000025386.1
product: 222476
fast: false
reversible: false
is: ENSMUSG00000064330.4
is: ENSMUSG00000024575.6
name: _3',5'-cyclic-nucleotide phosphodiesterase
is: ENSMUSG00000029491.6
product: 222488
is: ENSMUSG00000024992.6
reactant: 222464
reactant: 222452
notes: R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h

222476
type: SpeciesReference
stoichiometry: 1.0
species: 174986

222488
type: SpeciesReference
stoichiometry: 1.0
species: 175722

222464
type: SpeciesReference
stoichiometry: 1.0
species: 175614

222452
type: SpeciesReference
stoichiometry: 1.0
species: 161660

955331
type: Reaction
product: 284968
fast: false
reactant: 284932
product: 284956
notes: R_TRIODTHYt2 subsystem: Transport, Extracellular R_TRIODTHYt2 equation: triodthy[e] <==> triodthy[c] R_THYOXt2 subsystem: Transport, Extracellular R_THYOXt2 equation: thyox-L[e] <==> thyox-L[c]
is: ENSMUSG00000033965.4
reversible: true
reactant: 284944

284968
type: SpeciesReference
stoichiometry: 1.0
species: 187247

284932
type: SpeciesReference
stoichiometry: 1.0
species: 187044

284956
type: SpeciesReference
stoichiometry: 1.0
species: 187032

284944
type: SpeciesReference
stoichiometry: 1.0
species: 187259

187259
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Triiodothyronine_C15H12I3NO4

947456
type: Reaction
reactant: 209776
fast: false
reactant: 209764
reactant: 209752
notes: R_A4GNT1g subsystem: O-Glycan Biosynthesis R_A4GNT1g equation: [g] : T_antigen + uacgam --> gncore1 + h + udp R_A4GNT2g subsystem: O-Glycan Biosynthesis R_A4GNT2g equation: [g] : core2 + uacgam --> gncore2 + h + udp
is: ENSMUSG00000037953.7
product: 209824
reversible: false
product: 209788
product: 209812
product: 209800

209776
type: SpeciesReference
stoichiometry: 1.0
species: 164306

209764
type: SpeciesReference
stoichiometry: 1.0
species: 168605

209752
type: SpeciesReference
stoichiometry: 2.0
species: 187572

209824
type: SpeciesReference
stoichiometry: 1.0
species: 175058

209788
type: SpeciesReference
stoichiometry: 2.0
species: 187608

209812
type: SpeciesReference
stoichiometry: 1.0
species: 175046

209800
type: SpeciesReference
stoichiometry: 2.0
species: 175746

955439
type: Reaction
product: 287236
reactant: 286910
product: 287116
product: 287260
reactant: 286922
reactant: 286754
reactant: 286778
reactant: 286343
reactant: 286499
reactant: 286814
product: 287296
reactant: 286596
reactant: 286355
product: 286983
product: 287031
reactant: 286608
reactant: 286850
product: 287055
product: 287007
reactant: 286403
product: 286971
reactant: 286657
reactant: 286548
reactant: 286620
reactant: 286730
reversible: false
reactant: 286475
reactant: 286669
product: 287272
reactant: 286766
product: 287152
reactant: 286742
product: 287067
reactant: 286487
fast: false
notes: R_AHEXASEly subsystem: N-Glycan Degradation R_AHEXASEly equation: [l] : (2) h2o + n2m2mn --> (2) acgam + m2mn R_NACHEX4ly subsystem: Chondroitin sulfate degradation R_NACHEX4ly equation: [l] : cs_c_deg1 + h2o --> acgal + cs_c_deg2 R_NACHEX14ly subsystem: Keratan sulfate degradation R_NACHEX14ly equation: [l] : h2o + ksi_deg19 --> acgam + ksi_deg20 R_NACHEXA13ly subsystem: Keratan sulfate degradation R_NACHEXA13ly equation: [l] : (2) h2o + ksi_deg18 --> acgam + h + ksi_deg20 + so4 R_NACHEX20ly subsystem: Keratan sulfate degradation R_NACHEX20ly equation: [l] : h2o + ksi_deg37 --> acgam + ksi_deg38 R_NACHEXA2ly subsystem: Chondroitin sulfate degradation R_NACHEXA2ly equation: [l] : cs_b + (2) h2o --> acgal + cs_b_deg2 + h + so4 R_NACHEX19ly subsystem: Keratan sulfate degradation R_NACHEX19ly equation: [l] : h2o + ksi_deg34 --> acgam + ksi_deg35 R_NACHEXA18ly subsystem: Keratan sulfate degradation R_NACHEXA18ly equation: [l] : (2) h2o + ksi_deg33 --> acgam + h + ksi_deg35 + so4 R_NACHEX21ly subsystem: Keratan sulfate degradation R_NACHEX21ly equation: [l] : h2o + ksi_deg39 --> acgam + ksi_deg40 R_NACHEXA22ly subsystem: Keratan sulfate degradation R_NACHEXA22ly equation: [l] : (3) h2o + ksii_core4_deg3 --> (2) acgam + h + ksii_core2_deg5 + so4 R_NACHEX23ly subsystem: Keratan sulfate degradation R_NACHEX23ly equation: [l] : h2o + ksii_core2_deg4 --> acgam + ksii_core2_deg5 R_NACHEX10ly subsystem: Keratan sulfate degradation R_NACHEX10ly equation: [l] : (2) h2o + ksi_deg7 --> (2) acgam + ksi_deg8 R_NACHEX5ly subsystem: Chondroitin sulfate degradation R_NACHEX5ly equation: [l] : cs_c_deg4 + h2o --> acgal + cs_c_deg5 R_NACHEX2ly subsystem: Chondroitin sulfate degradation R_NACHEX2ly equation: [l] : cs_a_deg4 + h2o --> acgal + cs_a_deg5 R_NACHEXA14ly subsystem: Keratan sulfate degradation R_NACHEXA14ly equation: [l] : (2) h2o + ksi_deg21 --> acgam + h + ksi_deg23 + so4 R_NACHEXA17ly subsystem: Keratan sulfate degradation R_NACHEXA17ly equation: [l] : (2) h2o + ksi_deg30 --> …
product: 287176
reactant: 286706
reactant: 286415
reactant: 286572
product: 287248
reactant: 286536
reactant: 286427
reactant: 286584
reactant: 286790
reactant: 286718
product: 287104
reactant: 286886
reactant: 286645
reactant: 286682
product: 287043
is: ENSMUSG00000021665.6
reactant: 286632
reactant: 286694
product: 287320
reactant: 286947
product: 287200
product: 287164
reactant: 286935
reactant: 286391
reactant: 286379
reactant: 286451
reactant: 286959
product: 287188
product: 287224
reactant: 286560
product: 287308
reactant: 286524
product: 286995
is: http://identifiers.org/ec-code/3.2.1.52
product: 287128
reactant: 286511
reactant: 286802
product: 287284
product: 287019
reactant: 286898
reactant: 286826
reactant: 286439
reactant: 286367

287236
type: SpeciesReference
stoichiometry: 2.0
species: 169175

169175
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 5_C23H36O24S

286910
type: SpeciesReference
stoichiometry: 1.0
species: 177893

177893
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 33_C76H125N5O62S2

287116
type: SpeciesReference
stoichiometry: 2.0
species: 169285

287260
type: SpeciesReference
stoichiometry: 2.0
species: 169430

169430
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 7_C23H35O27S2

286922
type: SpeciesReference
stoichiometry: 1.0
species: 177688

177688
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 19_C146H236N10O124S6

286754
type: SpeciesReference
stoichiometry: 1.0
species: 177639

177639
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 15_C160H257N11O140S8

286778
type: SpeciesReference
stoichiometry: 1.0
species: 177942

177942
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initial amount: NaN
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name: keratan sulfate I, degradation product 37_C62H104N4O46

286343
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species: 169007

286499
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169127
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name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 1_C45H68N2O43S2

286814
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species: 169224

169224
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name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 1_C45H66N2O49S4

287296
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species: 177591

177591
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286596
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species: 177967

177967
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name: keratan sulfate I, degradation product 39_C48H81N3O36

286355
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286983
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species: 172427

172427
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287031
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286608
type: SpeciesReference
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286850
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species: 177809

177809
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287055
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178641
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287007
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species: 175866

286403
type: SpeciesReference
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species: 169393

286971
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species: 168983

286657
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species: 178846

178846
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initial concentration: NaN
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286548
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178003
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initial concentration: NaN
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name: keratan sulfate I, degradation product 41_C34H58N2O26

286620
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species: 169079

286730
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species: 177930

177930
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has only substance units: false
initial concentration: NaN
initial amount: NaN
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286475
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species: 178834

178834
type: Species
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: keratan sulfate II (core 4-linked), degradation product 3_C66H107N6O51S2X

286669
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species: 177603

287272
type: SpeciesReference
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species: 169019

286766
type: SpeciesReference
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species: 169187

169187
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: chondroitin sulfate C (GalNAc6S-GlcA), free chain_C45H67N2O46S3

287152
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species: 178605

178605
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: keratan sulfate II (core 2-linked), degradation product 5_C50H82N4O38SX

286742
type: SpeciesReference
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species: 169443

287067
type: SpeciesReference
stoichiometry: 2.0
species: 177833

177833
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: keratan sulfate I, degradation product 29_C96H157N6O80S3

286487
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species: 177676

177676
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 18_C146H235N10O127S7

287176
type: SpeciesReference
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species: 178063

178063
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: keratan sulfate I, degradation product 8_C194H311N13O171S10

286706
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species: 169369

169369
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 2_C45H66N2O49S4

286415
type: SpeciesReference
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species: 169297

169297
type: Species
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), free chain_C45H65N2O52S5

286572
type: SpeciesReference
stoichiometry: 1.0
species: 177772

287248
type: SpeciesReference
stoichiometry: 2.0
species: 177918

286536
type: SpeciesReference
stoichiometry: 1.0
species: 177906

177906
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 34_C76H126N5O59S1

286427
type: SpeciesReference
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species: 169043

286584
type: SpeciesReference
stoichiometry: 1.0
species: 178617

286790
type: SpeciesReference
stoichiometry: 1.0
species: 181314

181314
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: reducing GlcNAc removed form of n2m2nmasn (w/o peptide)_C50H84N4O36

286718
type: SpeciesReference
stoichiometry: 1.0
species: 178075

287104
type: SpeciesReference
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species: 177724

286886
type: SpeciesReference
stoichiometry: 1.0
species: 175818

175818
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: hyaluronan degradation product 1_C22H33N2O16

286645
type: SpeciesReference
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species: 178593

178593
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: keratan sulfate II (core 2-linked), degradation product 4_C58H95N5O43SX

286682
type: SpeciesReference
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species: 169273

169273
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 5_C31H48NO32S2

287043
type: SpeciesReference
stoichiometry: 24.0
species: 185679

286632
type: SpeciesReference
stoichiometry: 1.0
species: 177651

286694
type: SpeciesReference
stoichiometry: 82.0
species: 175650

287320
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species: 169139

169139
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 2_C37H55NO38S2

286947
type: SpeciesReference
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species: 168971

287200
type: SpeciesReference
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species: 177797

177797
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: keratan sulfate I, degradation product 26_C110H179N7O93S4

287164
type: SpeciesReference
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species: 169055

286935
type: SpeciesReference
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species: 181236

181236
type: Species
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has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: de-Fuc, reducing GlcNAc removed, de-Sia, de-Gal form of PA6 (w/o peptide linkage)_C42H71N3O31

286391
type: SpeciesReference
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species: 169418

169418
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 6_C31H48NO32S2

286379
type: SpeciesReference
stoichiometry: 1.0
species: 169031

286451
type: SpeciesReference
stoichiometry: 1.0
species: 177821

177821
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 28_C104H170N7O85S3

286959
type: SpeciesReference
stoichiometry: 1.0
species: 178039

287188
type: SpeciesReference
stoichiometry: 2.0
species: 177627

177627
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 14_C166H267N11O145S8

287224
type: SpeciesReference
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species: 179956

179956
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: (alpha-D-mannosyl)2-beta-D-mannosyl-N-acetylglucosamine_C26H45NO21

286560
type: SpeciesReference
stoichiometry: 1.0
species: 177579

177579
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 10_C188H302N13O163S9

287308
type: SpeciesReference
stoichiometry: 2.0
species: 169381

169381
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 3_C37H53NO44S4

286524
type: SpeciesReference
stoichiometry: 1.0
species: 169260

169260
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 4_C31H47NO35S3

286995
type: SpeciesReference
stoichiometry: 2.0
species: 177881

177881
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 32_C82H135N5O67S2

287128
type: SpeciesReference
stoichiometry: 2.0
species: 177760

286511
type: SpeciesReference
stoichiometry: 1.0
species: 178654

178654
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate II (core 2-linked), degradation product 9_C30H50N3O20X

286802
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species: 169163

169163
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 4_C31H49NO29S

287284
type: SpeciesReference
stoichiometry: 41.0
species: 164884

164884
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: N-Acetyl-D-glucosamine_C8H15NO6

287019
type: SpeciesReference
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species: 164763

164763
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: N-Acetyl-D-galactosamine_C8H15NO6

286898
type: SpeciesReference
stoichiometry: 1.0
species: 177736

177736
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 21_C132H213N9O114S6

286826
type: SpeciesReference
stoichiometry: 1.0
species: 178581

286439
type: SpeciesReference
stoichiometry: 1.0
species: 177748

177748
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 22_C132H214N9O111S5

286367
type: SpeciesReference
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species: 177615

177615
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 13_C174H280N12O150S8

287140
type: SpeciesReference
stoichiometry: 2.0
species: 177664

286838
type: SpeciesReference
stoichiometry: 1.0
species: 178629

178629
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate II (core 2-linked), degradation product 7_C44H73N4O30X

286862
type: SpeciesReference
stoichiometry: 1.0
species: 177784

177784
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 25_C118H192N8O98S4

287091
type: SpeciesReference
stoichiometry: 2.0
species: 169236

169236
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 2_C37H53NO44S4

286874
type: SpeciesReference
stoichiometry: 1.0
species: 177857

177857
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 30_C90H147N6O75S3

287212
type: SpeciesReference
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species: 177954

286463
type: SpeciesReference
stoichiometry: 1.0
species: 178051

178051
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: keratan sulfate I, degradation product 7_C210H337N15O181S10

287079
type: SpeciesReference
stoichiometry: 24.0
species: 175758

955764
type: Reaction
product: 290809
product: 290821
product: 290773
is: http://identifiers.org/ec-code/2.7.1.151
is: ENSMUSG00000060733.5
product: 290785
reactant: 290724
reactant: 290712
is: http://identifiers.org/ec-code/2.7.1.127
reactant: 290737
fast: false
notes: R_MI145P6Kn subsystem: Inositol Phosphate Metabolism R_MI145P6Kn equation: [n] : atp + mi145p --> adp + h + mi1456p R_MI1456PKn subsystem: Inositol Phosphate Metabolism R_MI1456PKn equation: [n] : atp + mi1456p --> adp + h + mi13456p R_MI1346PKn subsystem: Inositol Phosphate Metabolism R_MI1346PKn equation: [n] : atp + mi1346p --> adp + h + mi13456p R_MI1345PKn subsystem: Inositol Phosphate Metabolism R_MI1345PKn equation: [n] : atp + mi1345p --> adp + h + mi13456p R_MI145PKn subsystem: Inositol Phosphate Metabolism R_MI145PKn equation: [n] : atp + mi145p --> adp + h + mi1345p
product: 290797
reactant: 290761
reactant: 290749
reversible: false
is: http://identifiers.org/ec-code/2.7.1.140

290809
type: SpeciesReference
stoichiometry: 3.0
species: 180849

290821
type: SpeciesReference
stoichiometry: 5.0
species: 165423

290773
type: SpeciesReference
stoichiometry: 1.0
species: 180909

180909
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: _1D-myo-Inositol 1,4,5,6-tetrakisphosphate_C6H8O18P4

290785
type: SpeciesReference
stoichiometry: 1.0
species: 180873

180873
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: _1D-myo-Inositol 1,3,4,5-tetrakisphosphate_C6H8O18P4

290724
type: SpeciesReference
stoichiometry: 1.0
species: 180885

290712
type: SpeciesReference
stoichiometry: 1.0
species: 180909

290737
type: SpeciesReference
stoichiometry: 1.0
species: 180873

290797
type: SpeciesReference
stoichiometry: 5.0
species: 175782

290761
type: SpeciesReference
stoichiometry: 5.0
species: 166940

290749
type: SpeciesReference
stoichiometry: 2.0
species: 180933

180933
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160586
name: _1D-myo-Inositol 1,4,5-trisphosphate_C6H9O15P3

186235
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: D-Tagatose_C6H12O6

167772
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N,N'-Diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1185H1940N20O170P20

175999
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Hexadecenoyl carnitine_C23H43NO4

946338
type: Reaction
reactant: 198847
is: ENSMUSG00000027737.4
fast: false
name: L-cystine/L-glutamate exchanger
product: 198871
reactant: 198859
product: 198883
reversible: false
notes: R_CYSTGLUex subsystem: Transport, Extracellular R_CYSTGLUex equation: Lcystin[e] + glu-L[c] --> Lcystin[c] + glu-L[e]

198847
type: SpeciesReference
stoichiometry: 1.0
species: 174442

198871
type: SpeciesReference
stoichiometry: 1.0
species: 174454

198859
type: SpeciesReference
stoichiometry: 1.0
species: 163811

198883
type: SpeciesReference
stoichiometry: 1.0
species: 163799

179292
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: Leukotriene B4_C20H31O4

949873
type: Reaction
is: ENSMUSG00000047674.1
is: http://identifiers.org/ec-code/1.2.4.1
reactant: 230526
name: pyruvate dehydrogenase
reactant: 230514
is: ENSMUSG00000000168.2
product: 230550
is: ENSMUSG00000031299.8
product: 230562
notes: R_PDHm subsystem: Glycolysis/Gluconeogenesis R_PDHm equation: [m] : coa + nad + pyr --> accoa + co2 + nadh
fast: false
reactant: 230502
product: 230538
reversible: false
is: ENSMUSG00000021748.7

230526
type: SpeciesReference
stoichiometry: 1.0
species: 181461

230514
type: SpeciesReference
stoichiometry: 1.0
species: 184843

230550
type: SpeciesReference
stoichiometry: 1.0
species: 164607

230562
type: SpeciesReference
stoichiometry: 1.0
species: 181522

230502
type: SpeciesReference
stoichiometry: 1.0
species: 168545

230538
type: SpeciesReference
stoichiometry: 1.0
species: 168461

161963
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _3-Hydroxy-N6,N6,N6-trimethyl-L-lysine_C9H20N2O3

946072
type: Reaction
reactant: 196744
product: 196805
product: 196819
product: 196830
reactant: 196768
is: ENSMUSG00000028479.8
product: 196792
reactant: 196780
is: http://identifiers.org/ec-code/2.7.1.60
reversible: false
product: 196842
fast: false
notes: R_UAG2EMAi subsystem: Aminosugar Metabolism R_UAG2EMAi equation: [c] : h2o + uacgam --> acmana + h + udp R_AMANK subsystem: Aminosugar Metabolism R_AMANK equation: [c] : acmana + atp --> acmanap + adp + h
is: http://identifiers.org/ec-code/5.1.3.14
reactant: 196756

196744
type: SpeciesReference
stoichiometry: 1.0
species: 187560

196805
type: SpeciesReference
stoichiometry: 1.0
species: 165387

196819
type: SpeciesReference
stoichiometry: 1.0
species: 187584

196830
type: SpeciesReference
stoichiometry: 1.0
species: 165028

165028
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Acetyl-D-mannosamine_C8H15NO6

196768
type: SpeciesReference
stoichiometry: 1.0
species: 166904

196792
type: SpeciesReference
stoichiometry: 1.0
species: 165040

165040
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Acetyl-D-mannosamine 6-phosphate_C8H14NO9P

196780
type: SpeciesReference
stoichiometry: 1.0
species: 175614

196842
type: SpeciesReference
stoichiometry: 2.0
species: 175722

196756
type: SpeciesReference
stoichiometry: 1.0
species: 165028

954489
type: Reaction
product: 276999
reversible: false
reactant: 276927
product: 277011
product: 277023
is: ENSMUSG00000005043.6
fast: false
notes: R_HS1ly subsystem: Heparan sulfate degradation R_HS1ly equation: [l] : h2o + hs_deg1 --> h + hs_deg2 + so4 R_HS2ly subsystem: Heparan sulfate degradation R_HS2ly equation: [l] : h2o + hs_deg6 --> h + hs_deg7 + so4 R_HS4ly subsystem: Heparan sulfate degradation R_HS4ly equation: [l] : h2o + hs_deg18 --> h + hs_deg19 + so4 R_HS3ly subsystem: Heparan sulfate degradation R_HS3ly equation: [l] : h2o + hs_deg12 --> h + hs_deg13 + so4
reactant: 276951
product: 276987
reactant: 276939
is: http://identifiers.org/ec-code/3.10.1.1
product: 276975
reactant: 276915
reactant: 276903
product: 276963

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type: SpeciesReference
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species: 175758

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type: SpeciesReference
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species: 176481

176481
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 12_C55H82N3O64S6

277011
type: SpeciesReference
stoichiometry: 1.0
species: 176722

176722
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 7_C67H99N4O80S8

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species: 176565

276951
type: SpeciesReference
stoichiometry: 1.0
species: 176710

176710
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 6_C67H98N4O83S9

276987
type: SpeciesReference
stoichiometry: 1.0
species: 176661

176661
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 2_C79H116N5O96S10

276939
type: SpeciesReference
stoichiometry: 1.0
species: 176553

276975
type: SpeciesReference
stoichiometry: 4.0
species: 185679

276915
type: SpeciesReference
stoichiometry: 4.0
species: 175650

276903
type: SpeciesReference
stoichiometry: 1.0
species: 176577

176577
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 1_C79H115N5O99S11

276963
type: SpeciesReference
stoichiometry: 1.0
species: 176493

176493
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160562
name: heparan sulfate, degradation product 13_C55H83N3O61S5

179751
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: gamma-linolenyl carnitine_C25H43NO4

945531
type: Reaction
reversible: false
name: N-acetylglucosamine-6-phosphate deacetylase
reactant: 192398
notes: R_AGDC subsystem: Aminosugar Metabolism R_AGDC equation: [c] : acgam6p + h2o --> ac + gam6p
is: ENSMUSG00000036820.4
is: http://identifiers.org/ec-code/3.5.1.25
reactant: 192410
fast: false
product: 192435
product: 192423

192398
type: SpeciesReference
stoichiometry: 1.0
species: 175614

192410
type: SpeciesReference
stoichiometry: 1.0
species: 164848

164848
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: N-Acetyl-D-glucosamine 6-phosphate_C8H14NO9P

192435
type: SpeciesReference
stoichiometry: 1.0
species: 164438

192423
type: SpeciesReference
stoichiometry: 1.0
species: 173875

177011
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160598
name: Hypoxanthine_C5H4N4O

187875
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160550
name: UMP_C9H11N2O9P

953757
type: Reaction
fast: false
reactant: 269724
name: phosphogluconate dehydrogenase
product: 269748
notes: R_GND subsystem: Pentose Phosphate Pathway R_GND equation: [c] : 6pgc + nadp --> co2 + nadph + ru5p-D
reversible: false
product: 269760
is: http://identifiers.org/ec-code/1.1.1.44
reactant: 269712
is: ENSMUSG00000028961.8
product: 269736

269724
type: SpeciesReference
stoichiometry: 1.0
species: 163450

163450
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: _6-Phospho-D-gluconate_C6H10O10P

269748
type: SpeciesReference
stoichiometry: 1.0
species: 168436

269760
type: SpeciesReference
stoichiometry: 1.0
species: 181631

269712
type: SpeciesReference
stoichiometry: 1.0
species: 181558

269736
type: SpeciesReference
stoichiometry: 1.0
species: 185145

184963
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: fatty acid retinol_C20H29OFULLR2CO

164354
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Tyr-194 of apo-glycogenin protein (primer for glycogen synthesis)_XOH

954249
type: Reaction
product: 275238
is: ENSMUSG00000031910.7
reversible: false
is: http://identifiers.org/ec-code/2.4.1.212
reactant: 275213
is: ENSMUSG00000022367.6
notes: R_HAS1 subsystem: Hyaluronan Metabolism R_HAS1 equation: uacgam[c] + udpglcur[c] --> (2) h[c] + ha_pre1[e] + (2) udp[c] R_HAS2 subsystem: Hyaluronan Metabolism R_HAS2 equation: ha_pre1[e] + uacgam[c] + udpglcur[c] --> (2) h[c] + ha[e] + (2) udp[c]
product: 275250
reactant: 275226
is: ENSMUSG00000003665.5
reactant: 275201
product: 275274
product: 275262
fast: false

275238
type: SpeciesReference
stoichiometry: 1.0
species: 175854

175854
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: hyaluronan biosynthesis, precursor 1_C14H20NO11

275213
type: SpeciesReference
stoichiometry: 2.0
species: 187560

275250
type: SpeciesReference
stoichiometry: 1.0
species: 175830

175830
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: hyaluronan_C28H40N2O22

275226
type: SpeciesReference
stoichiometry: 2.0
species: 187777

187777
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160514
name: UDP-D-glucuronate_C15H19N2O18P2

275201
type: SpeciesReference
stoichiometry: 1.0
species: 175854

275274
type: SpeciesReference
stoichiometry: 4.0
species: 175722

275262
type: SpeciesReference
stoichiometry: 4.0
species: 187584

946807
type: Reaction
reactant: 203664
reversible: false
fast: false
name: Ap4A hydrolase, asymmetrically
is: http://identifiers.org/ec-code/3.6.1.17
product: 203700
product: 203688
notes: R_AP4AH1 subsystem: Nucleotides R_AP4AH1 equation: [c] : ap4a + h2o --> amp + atp + (2) h
product: 203676
reactant: 203652
is: ENSMUSG00000028443.5

203664
type: SpeciesReference
stoichiometry: 1.0
species: 166399

203700
type: SpeciesReference
stoichiometry: 2.0
species: 175722

203688
type: SpeciesReference
stoichiometry: 1.0
species: 166219

203676
type: SpeciesReference
stoichiometry: 1.0
species: 166904

203652
type: SpeciesReference
stoichiometry: 1.0
species: 175614

954574
type: Reaction
reversible: false
is: http://identifiers.org/ec-code/1.1.1.14
name: D-sorbitol dehydrogenase (D-fructose producing)
product: 277726
fast: false
product: 277750
product: 277738
is: ENSMUSG00000027227.5
reactant: 277701
reactant: 277714
notes: R_SBTD_D2 subsystem: Fructose and Mannose Metabolism R_SBTD_D2 equation: [c] : nad + sbt-D --> fru + h + nadh

277726
type: SpeciesReference
stoichiometry: 1.0
species: 172932

277750
type: SpeciesReference
stoichiometry: 1.0
species: 181510

277738
type: SpeciesReference
stoichiometry: 1.0
species: 175722

277701
type: SpeciesReference
stoichiometry: 1.0
species: 181437

277714
type: SpeciesReference
stoichiometry: 1.0
species: 185349

163595
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: heptaglutamyl folate (DHF)_C49H55N13O24

176253
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160538
name: Histamine_C5H10N3

172668
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: Fe2+_Fe

947624
type: Reaction
product: 211090
reactant: 211066
reactant: 211078
reversible: false
notes: R_METLEUex subsystem: Transport, Extracellular R_METLEUex equation: leu-L[c] + met-L[e] --> leu-L[e] + met-L[c]
product: 211102
fast: false
name: Methionine/Leucine exchange (Met in)
is: ENSMUSG00000040010.7

211090
type: SpeciesReference
stoichiometry: 1.0
species: 179243

211066
type: SpeciesReference
stoichiometry: 1.0
species: 180752

211078
type: SpeciesReference
stoichiometry: 1.0
species: 179231

211102
type: SpeciesReference
stoichiometry: 1.0
species: 180740

950198
type: Reaction
product: 235665
reactant: 235640
reactant: 235592
product: 235713
product: 235653
fast: false
product: 235725
product: 235701
reactant: 235604
reactant: 235580
product: 235689
reactant: 235628
reactant: 235616
reversible: false
product: 235677
is: http://identifiers.org/ec-code/1.5.1.8
reactant: 235568
is: http://identifiers.org/ec-code/1.5.1.10
is: ENSMUSG00000029695.6
notes: R_SACCD3m subsystem: Lysine Metabolism R_SACCD3m equation: [m] : akg + h + lys-L + nadph --> h2o + nadp + saccrp-L R_SACCD4m subsystem: Lysine Metabolism R_SACCD4m equation: [m] : h2o + nadp + saccrp-L --> L2aadp6sa + glu-L + h + nadph

235665
type: SpeciesReference
stoichiometry: 1.0
species: 185301

185301
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 160574
name: L-Saccharopine_C11H19N2O6

235640
type: SpeciesReference
stoichiometry: 1.0
species: 175770

235592
type: SpeciesReference
stoichiometry: 1.0
species: 179871