MODEL0912160000
type: SBMLModel
parameter: 609656
rule: 609562
parameter: 609668
rule: 609572
parameter: 609599
name: Guyton1972_CapillaryDynamics
parameter: 609591
rule: 609539
parameter: 609632
compartment: 609530
rule: 609571
rule: 609535
rule: 609581
parameter: 609645
parameter: 609608
parameter: 609647
parameter: 609639
parameter: 609666
rule: 609580
rule: 609566
time units: 640312
parameter: 609612
parameter: 609624
parameter: 609614
parameter: 609650
rule: 609533
parameter: 609618
rule: 609543
parameter: 609642
rule: 609583
parameter: 609657
parameter: 609594
area units: area
parameter: 609627
rule: 609534
rule: 609574
parameter: 609660
parameter: 609603
parameter: 609605
parameter: 609630
notes: This a model from the article: Circulation: overall regulation. Guyton AC, Coleman TG, Granger HJ. Annu Rev Physiol 1972;34:13-46 4334846 , Abstract: This article is an experiment, one undertaken primarily because of the long-term belief of Dr. Victor Hall, Editor of the Annual Review of Physiology fo r many years, that physiology is, or at least should be, an analytical subject, and that a method not utilized to its fullest advantage for organizing review material is the systems analysis. Furthermore, one of the most likely areas in physiology for which a systems analysis could be of value would be in a discussion of circulatory regulation. Therefore, this article was undertaken directly at the request of the editors of the A ogy to attempt the welding togeth er of a systemsn annuaally Rsiesv ioewf coifr cPuhlaytsoiorlyregulation with a review of the current literature in this field. The systems analysis of circulatory regulation developed for this article is based on earlier, much less extensive analyses (Guyton and Coleman 1, 2); it i s illustrated in Figure 1. This analysis is comprised of 354 blocks, each of which represents one or more mathematical equations describing some physiological facet of circulatory function. In general, each of the functional blocks has been the subject of research investigation by one or many investigator s, but the analysis is based on cumulative knowledge of the circulation rather than simply on current literature. Therefore, the analysis presented here is not a review of the current literature but is a framework to show how the different regulations operate together in the overall system. Later in this review we will attempt to show some of the voids still present in our knowledge of circulatory regulation (which is perhaps the most important value of performing systems analyses), and we will discuss the current research that is attempting to fill these voids. A criticism that has often been made against systems analyses, and ver…
rule: 609559
rule: 609550
parameter: 609588
parameter: 609673
parameter: 609663
parameter: 609597
parameter: 609665
rule: 609577
parameter: 609611
parameter: 609621
parameter: 609593
parameter: 609644
parameter: 609636
parameter: 609617
rule: 609568
rule: 609578
rule: 609536
rule: 609575
rule: 609558
rule: 609554
rule: 609584
parameter: 609626
volume units: 970346
parameter: 609654
rule: 609551
parameter: 609669
parameter: 609659
parameter: 609596
rule: 609542
parameter: 609600
parameter: 609602
curated: false
parameter: 609606
parameter: 609633
parameter: 609635
parameter: 609672
parameter: 609662
parameter: 609609

609656
type: Parameter
constant: true
units: dimensionless
value: 15.0
name: PCR

609668
type: Parameter
constant: true
units: dimensionless
value: -2.0
name: PGHF

609599
type: Parameter
constant: false
units: dimensionless
value: 16.9144
name: PC

609591
type: Parameter
constant: true
units: dimensionless
value: 2.77751
name: RVS

609632
type: Parameter
constant: false
units: dimensionless
value: NaN
name: PGH

609530
type: Compartment
constant: true
units: litre
size: 1.0
spatial dimensions: 3.0

609645
type: Parameter
constant: false
units: dimensionless
value: NaN
name: VG

609608
type: Parameter
constant: false
units: dimensionless
value: NaN
name: CPPD

609647
type: Parameter
constant: false
units: dimensionless
value: NaN
name: VIF

609639
type: Parameter
constant: false
units: dimensionless
value: NaN
name: PTS

609666
type: Parameter
constant: true
units: dimensionless
value: 2.0
name: CMPTSS

609612
type: Parameter
constant: false
units: dimensionless
value: NaN
name: DPC

609624
type: Parameter
constant: false
units: dimensionless
value: NaN
name: DPI

609614
type: Parameter
constant: false
units: dimensionless
value: 216.243
name: PRP

609650
type: Parameter
constant: true
units: dimensionless
value: 0.0
name: TRPL

609618
type: Parameter
constant: false
units: dimensionless
value: NaN
name: VTS

609642
type: Parameter
constant: false
units: dimensionless
value: NaN
name: PLD1

609657
type: Parameter
constant: true
units: dimensionless
value: 2.728E-14
name: LPK

609594
type: Parameter
constant: true
units: dimensionless
value: 0.0123238
name: VPF

609627
type: Parameter
constant: false
units: dimensionless
value: NaN
name: PTCPR

609660
type: Parameter
constant: true
units: dimensionless
value: 2.53E-4
name: CPK

609603
type: Parameter
constant: false
units: dimensionless
value: NaN
name: VPD

609605
type: Parameter
constant: false
units: dimensionless
value: NaN
name: CPP

609630
type: Parameter
constant: false
units: dimensionless
value: NaN
name: CHY

609588
type: Parameter
constant: true
units: dimensionless
value: 14.8548
name: VEC

609673
type: Parameter
constant: true
units: dimensionless
value: 4.2
name: PLDF

609663
type: Parameter
constant: true
units: dimensionless
value: 0.005
name: TSSLTC

609597
type: Parameter
constant: true
units: dimensionless
value: 3.71612
name: PVS

609665
type: Parameter
constant: true
units: dimensionless
value: 60.0
name: HYL

609611
type: Parameter
constant: false
units: dimensionless
value: NaN
name: PRCD

609621
type: Parameter
constant: false
units: dimensionless
value: 0.0
name: VTS2

609593
type: Parameter
constant: true
units: dimensionless
value: -4.078E-7
name: DFP

609644
type: Parameter
constant: false
units: dimensionless
value: NaN
name: PLD

609636
type: Parameter
constant: false
units: dimensionless
value: NaN
name: PTT

609617
type: Parameter
constant: false
units: dimensionless
value: NaN
name: PPC

609626
type: Parameter
constant: false
units: dimensionless
value: NaN
name: CPI

609654
type: Parameter
constant: true
units: dimensionless
value: 1.0
name: PCE

609669
type: Parameter
constant: true
units: dimensionless
value: 0.8092
name: GCOPF

609659
type: Parameter
constant: true
units: dimensionless
value: 0.03
name: LPPR

609596
type: Parameter
constant: true
units: dimensionless
value: 2.79521
name: BFN

609600
type: Parameter
constant: false
units: dimensionless
value: NaN
name: VTC

609602
type: Parameter
constant: false
units: dimensionless
value: 3.00449
name: VP

609606
type: Parameter
constant: false
units: dimensionless
value: NaN
name: DLP

609633
type: Parameter
constant: false
units: dimensionless
value: NaN
name: POSHYL

609635
type: Parameter
constant: false
units: dimensionless
value: NaN
name: PTC

609672
type: Parameter
constant: true
units: dimensionless
value: 6.0
name: VTSF

609662
type: Parameter
constant: true
units: dimensionless
value: 0.15
name: TSSLML

609609
type: Parameter
constant: false
units: dimensionless
value: NaN
name: VTCPL

609620
type: Parameter
constant: false
units: dimensionless
value: NaN
name: VTS1

609623
type: Parameter
constant: false
units: dimensionless
value: 279.945
name: TSP

609651
type: Parameter
constant: true
units: dimensionless
value: 40.0
name: CPR

609615
type: Parameter
constant: false
units: dimensionless
value: NaN
name: DPP

609648
type: Parameter
constant: true
units: dimensionless
value: 0.01167
name: CFC

609638
type: Parameter
constant: false
units: dimensionless
value: NaN
name: PIF

609641
type: Parameter
constant: false
units: dimensionless
value: NaN
name: VTL

609629
type: Parameter
constant: false
units: dimensionless
value: NaN
name: DPL

609653
type: Parameter
constant: true
units: dimensionless
value: 8.0
name: LPDE

609590
type: Parameter
constant: true
units: dimensionless
value: 4.4805E-6
name: PPD