BIOMD0000000426
type: SBMLModel
parameter: COPASI83
parameter: COPASI58
parameter: COPASI43
name: ENO [1]
rule: 225943
reaction: COPASI110
rule: 226075
parameter: COPASI62
reaction: COPASI90
reaction: COPASI104
parameter: 225499
rule: 226039
species: COPASI25
species: COPASI11
rule: 225919
units def: 225389
occurs in: http://identifiers.org/taxonomy/9606
parameter: COPASI46
function def: COPASI128
parameter: 225559
function def: COPASI115
parameter: 225763
parameter: COPASI67
reaction: COPASI94
reaction: COPASI108
compartment: COPASI2
rule: 226255
parameter: COPASI70
function def: COPASI121
volume units: 225341
rule: 226099
rule: 225979
parameter: 225487
parameter: 225691
species: COPASI10
name: RUPE
rule: 226111
rule: 226219
reaction: COPASI99
parameter: COPASI76
parameter: 225751
function def: COPASI133
name: PGLM
parameter: 225607
species: COPASI19
rule: 226051
rule: 225931
reaction: COPASI101
function def: COPASI125
parameter: 225703
parameter: 225679
parameter: COPASI54
reaction: COPASI87
species: COPASI13
name: AK [1]
rule: 226135
rule: 225991
function def: COPASI137
species: COPASI6
parameter: COPASI37
species: COPASI18
parameter: 225775
name: PGDH
name: PRPPS
rule: 226231
name: PFK
rule: 225955
parameter: COPASI82
species: COPASI33
parameter: 225667
parameter: COPASI57
parameter: COPASI41
parameter: COPASI42
function def: COPASI117
rule: 226195
parameter: 225727
name: TAL
function def: COPASI131
name: MPM [1]

COPASI83
type: Parameter
constant: false
value: 127800.0
name: DPHase_Vf

COPASI58
type: Parameter
constant: false
value: 58.9795390787319
name: PGYM_Vr

COPASI43
type: Parameter
constant: false
value: 6.03725213205671E-5
name: GPb_Vr

COPASI110
type: Reaction
product: 228858
kinetic law: 228870
reversible: true
reactant: 228846
name: DHase
fast: false
modifier: 580618
is version of: GO:0006116
modifier: 580630

228858
type: SpeciesReference
stoichiometry: 1.0
species: COPASI21

COPASI21
type: Species
is: SBO:0000247
initial amount: NaN
constant: false
is version of: CHEBI:13389
boundary condition: false
has only substance units: false
in compartment: COPASI2
name: NAD
initial concentration: 0.00134

COPASI2
type: Compartment
is version of: GO:0005623
constant: true
size: 1.0
spatial dimensions: 3.0
name: compartment

228882
type: LocalParameter
value: 300.0
name: Keq

228846
type: SpeciesReference
stoichiometry: 1.0
species: COPASI20

COPASI20
type: Species
initial concentration: 5.00000000000001E-6
is version of: CHEBI:16908
has only substance units: false
name: NADH
is: SBO:0000247
in compartment: COPASI2
initial amount: NaN
constant: false
boundary condition: true

COPASI62
type: Parameter
constant: false
value: 54.0471638909003
name: LDH_Vr

COPASI90
type: Reaction
reversible: true
modifier: 579800
reactant: 226902
fast: false
is version of: GO:0008742
name: RUPE
kinetic law: 226926
product: 226914
modifier: 579788

COPASI16
type: Species
has only substance units: false
initial amount: NaN
boundary condition: false
name: X5P
initial concentration: 2.42E-4
in compartment: COPASI2
constant: false
is version of: CHEBI:57737
is: SBO:0000247

226902
type: SpeciesReference
stoichiometry: 1.0
species: COPASI15

COPASI15
type: Species
constant: false
boundary condition: false
is: SBO:0000247
in compartment: COPASI2
has only substance units: false
is version of: CHEBI:58121
initial amount: NaN
name: RU5P
initial concentration: 1.43E-4

226974
type: LocalParameter
value: 5.0E-7
name: KX5P

226962
type: LocalParameter
value: 1.9E-7
name: KRu5P

226950
type: LocalParameter
value: 2.7
name: Keq_RUPE

226938
type: LocalParameter
value: 1.471
name: Vmax

226914
type: SpeciesReference
stoichiometry: 1.0
species: COPASI16

COPASI104
type: Reaction
modifier: 228294
kinetic law: 228306
modifier: 580414
product: 228270
modifier: 228282
reversible: true
product: 228258
modifier: 580378
modifier: 580366
modifier: 580390
reactant: 228234
modifier: 580354
modifier: 580402
name: PFK
reactant: 228246
fast: false
is version of: GO:0008443

COPASI27
type: Species
is: SBO:0000247
in compartment: COPASI2
has only substance units: false
initial amount: NaN
constant: true
initial concentration: 0.00108
boundary condition: true
is version of: CHEBI:30769
name: CIT

228426
type: LocalParameter
value: 5.0
name: Kfbp

228402
type: LocalParameter
value: 20.0
name: Kiatp

228438
type: LocalParameter
value: 247.0
name: Kapp

228414
type: LocalParameter
value: 5.0
name: Kadp

228318
type: LocalParameter
value: 2.1E-5
name: Katp

228366
type: LocalParameter
value: 1.0
name: Kf6p

228390
type: LocalParameter
value: 6.8
name: Kcit

228342
type: LocalParameter
value: 0.32
name: alfa

228378
type: LocalParameter
value: 4.1
name: L

228354
type: LocalParameter
value: 8.4E-7
name: Kf26bp

228330
type: LocalParameter
value: 0.98
name: beta

COPASI8
type: Species
constant: false
boundary condition: false
is: SBO:0000247
initial amount: NaN
is version of: CHEBI:40595
has only substance units: false
name: F16P
in compartment: COPASI2
initial concentration: 3.67E-4

228270
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

COPASI5
type: Species
name: ADP
boundary condition: true
in compartment: COPASI2
initial amount: NaN
has only substance units: false
is version of: CHEBI:16761
constant: false
is: SBO:0000247
initial concentration: 0.0027

COPASI28
type: Species
is version of: http://identifiers.org/pubchem.compound/105021
has only substance units: false
name: F26P
initial concentration: 3.67E-6
boundary condition: true
initial amount: NaN
in compartment: COPASI2
is: SBO:0000247
constant: true

228258
type: SpeciesReference
stoichiometry: 1.0
species: COPASI8

COPASI7
type: Species
name: F6P
initial concentration: 3.62E-5
is version of: CHEBI:15946
in compartment: COPASI2
initial amount: NaN
constant: false
has only substance units: false
is: SBO:0000247
boundary condition: false

228234
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

COPASI6
type: Species
in compartment: COPASI2
initial concentration: 0.0087
boundary condition: false
initial amount: NaN
name: ATP
is version of: CHEBI:15422
constant: false
is: SBO:0000247
has only substance units: false

228246
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

225499
type: Parameter
constant: true
value: 3.0E-5
name: PGLM_KG6P

COPASI25
type: Species
in compartment: COPASI2
is version of: CHEBI:18367
is: SBO:0000247
has only substance units: false
initial concentration: 0.02
boundary condition: true
constant: true
name: Pi
initial amount: NaN

COPASI11
type: Species
name: GLC_e
constant: true
initial concentration: 0.01
has only substance units: false
in compartment: COPASI2
occurs in: GO:0005783
is version of: CHEBI:17234
boundary condition: true
initial amount: NaN
is: SBO:0000247

225389
type: SBMLUnitsDef
unit: 225401
name: substance

225401
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

COPASI46
type: Parameter
constant: false
value: 135.42497838741
name: GAPDH_Vr

225559
type: Parameter
constant: true
value: 0.0017
name: GPa_KiGLYf

225763
type: Parameter
constant: true
value: 154.0
name: PGYM_Vmf

COPASI67
type: Parameter
constant: false
value: 86.85
name: HK_Vf

COPASI94
type: Reaction
modifier: 579932
modifier: 579956
name: TAL
product: 227406
product: 227418
reactant: 227382
reactant: 227394
modifier: 579968
fast: false
modifier: 579944
reversible: true
is version of: GO:0004801
kinetic law: 227430

COPASI19
type: Species
is: SBO:0000247
has only substance units: false
initial concentration: 8.58E-5
in compartment: COPASI2
initial amount: NaN
boundary condition: false
constant: false
is version of: CHEBI:15721
name: S7P

COPASI9
type: Species
is: SBO:0000247
initial concentration: 9.3E-4
initial amount: NaN
has only substance units: false
boundary condition: false
name: E4P
constant: false
is version of: CHEBI:48153
in compartment: COPASI2

227406
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

227418
type: SpeciesReference
stoichiometry: 1.0
species: COPASI9

227382
type: SpeciesReference
stoichiometry: 1.0
species: COPASI19

227394
type: SpeciesReference
stoichiometry: 1.0
species: COPASI18

COPASI18
type: Species
is: SBO:0000247
initial amount: NaN
initial concentration: 1.53E-4
constant: false
in compartment: COPASI2
has only substance units: false
name: GAP
boundary condition: false
is version of: CHEBI:17138

227466
type: LocalParameter
value: 8.23E-9
name: K1

227538
type: LocalParameter
value: 2.524
name: K7

227502
type: LocalParameter
value: 1.733E-7
name: K3

227478
type: LocalParameter
value: 4.765E-8
name: K2

227514
type: LocalParameter
value: 0.8683
name: K5

227490
type: LocalParameter
value: 0.4653
name: K6

227442
type: LocalParameter
value: 58.27
name: Vmax

227454
type: LocalParameter
value: 2.703
name: Keq_TAL

227526
type: LocalParameter
value: 6.095E-9
name: K4

COPASI108
type: Reaction
kinetic law: 228738
reactant: 228690
modifier: 580558
fast: false
name: LDH
product: 228714
modifier: 580546
is version of: GO:0004457
reversible: true
modifier: 580570
product: 228726
modifier: 580534
reactant: 228702

228762
type: LocalParameter
value: 1.0
name: beta

228750
type: LocalParameter
value: 1.0
name: alfa

228690
type: SpeciesReference
stoichiometry: 1.0
species: COPASI33

COPASI33
type: Species
initial amount: NaN
name: PYR
is: SBO:0000247
initial concentration: 0.00183
constant: false
in compartment: COPASI2
has only substance units: false
is version of: CHEBI:15361
boundary condition: false

COPASI34
type: Species
constant: true
initial concentration: 0.0155
has only substance units: false
initial amount: NaN
name: LAC
is version of: CHEBI:24996
is: SBO:0000247
in compartment: COPASI2
boundary condition: true

228714
type: SpeciesReference
stoichiometry: 1.0
species: COPASI34

228726
type: SpeciesReference
stoichiometry: 1.0
species: COPASI21

228702
type: SpeciesReference
stoichiometry: 1.0
species: COPASI20

COPASI70
type: Parameter
constant: false
value: 31.02
name: PGDH_Vf

225341
type: SBMLUnitsDef
unit: 225353
name: volume

225353
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: LITRE

225487
type: Parameter
constant: true
value: 7.364
name: PGLM_Vmaxf

225691
type: Parameter
constant: true
value: 5.1E-4
name: TPI_Kms

COPASI10
type: Species
has only substance units: false
is version of: CHEBI:16938
boundary condition: false
name: PGN
initial amount: NaN
constant: false
initial concentration: 1.0E-4
is: SBO:0000247
in compartment: COPASI2

COPASI99
type: Reaction
reactant: 227826
kinetic law: 227850
reversible: true
modifier: 580138
fast: false
modifier: 580126
name: TPI
product: 227838
is version of: GO:0004807

227826
type: SpeciesReference
stoichiometry: 1.0
species: COPASI18

COPASI29
type: Species
has only substance units: false
is: SBO:0000247
in compartment: COPASI2
name: DHAP
is version of: CHEBI:57642
boundary condition: false
initial concentration: 5.53E-4
initial amount: NaN
constant: false

227838
type: SpeciesReference
stoichiometry: 1.0
species: COPASI29

COPASI76
type: Parameter
constant: false
value: 73.41
name: PGK_Vf

225751
type: Parameter
constant: true
value: 0.029
name: GAPDH_Kp

225607
type: Parameter
constant: true
value: 0.0015
name: GPb_KG1P

COPASI101
type: Reaction
fast: false
modifier: 580246
is version of: GO:0004618
reversible: true
modifier: 580222
kinetic law: 227982
product: 227958
product: 227970
name: PGK
modifier: 580234
reactant: 227946
modifier: 580210
reactant: 227934

228006
type: LocalParameter
value: 1.0
name: beta

227994
type: LocalParameter
value: 1.0
name: alfa

227958
type: SpeciesReference
stoichiometry: 1.0
species: COPASI30

COPASI30
type: Species
has only substance units: false
in compartment: COPASI2
initial amount: NaN
is: SBO:0000247
is version of: CHEBI:17050
boundary condition: false
initial concentration: 3.07E-5
constant: false
name: PG3

227970
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

227946
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

COPASI14
type: Species
has only substance units: false
is: SBO:0000247
initial concentration: 6.29E-5
boundary condition: false
name: BPG
initial amount: NaN
in compartment: COPASI2
is version of: http://identifiers.org/pubchem.compound/683
constant: false

227934
type: SpeciesReference
stoichiometry: 1.0
species: COPASI14

225703
type: Parameter
constant: true
value: 2.2E-5
name: GAPDH_Kdpg

225679
type: Parameter
constant: true
value: 0.0016
name: TPI_Kmp

COPASI54
type: Parameter
constant: true
value: 0.381
name: TPI_Keq

COPASI87
type: Reaction
name: PGI
is version of: GO:0004347
modifier: 226507
modifier: 579608
modifier: 226495
kinetic law: 226530
modifier: 579620
fast: false
reversible: true
reactant: 226471
modifier: 579632
modifier: 579596
product: 226482
modifier: 579584
modifier: 226518

226566
type: LocalParameter
value: 1.5E-5
name: Kpg

226555
type: LocalParameter
value: 6.0E-5
name: Kfbp

226542
type: LocalParameter
value: 1.0E-6
name: Kery4p

226471
type: SpeciesReference
stoichiometry: 1.0
species: COPASI4

COPASI4
type: Species
is: SBO:0000247
in compartment: COPASI2
name: G6P
boundary condition: false
initial concentration: 0.00109
has only substance units: false
initial amount: NaN
is version of: CHEBI:17665
constant: false

226482
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

COPASI13
type: Species
boundary condition: false
constant: false
name: NADPH
in compartment: COPASI2
has only substance units: false
initial concentration: 1.87082E-5
is: SBO:0000247
initial amount: NaN
is version of: CHEBI:16464

COPASI37
type: Parameter
constant: true
value: 0.0114
name: Atot

225775
type: Parameter
constant: true
value: 1.2E-4
name: PGYM_Kmp

COPASI82
type: Parameter
constant: false
value: 4982000.0
name: DHase_Vf

225667
type: Parameter
constant: true
value: 9.0E-6
name: FBA_Kfbp

COPASI57
type: Parameter
constant: true
value: 1.6491
name: PGYM_Keq

COPASI41
type: Parameter
constant: true
value: 0.42
name: GPa_Keq

COPASI42
type: Parameter
constant: true
value: 16.62
name: GPb_Keq

225727
type: Parameter
constant: true
value: 1.9E-4
name: GAPDH_Kg3p

225523
type: Parameter
constant: true
value: 0.03347
name: GPa_Vmaxf

COPASI61
type: Parameter
constant: true
value: 3452.5
name: LDH_Keq

COPASI103
type: Reaction
reactant: 228126
modifier: 580318
is version of: GO:0009011
modifier: 580306
reactant: 228138
product: 228150
name: GS
reversible: true
modifier: 580342
fast: false
product: 228174
kinetic law: 228186
modifier: 580294
product: 228162
modifier: 580330

228126
type: SpeciesReference
stoichiometry: 1.0
species: COPASI24

COPASI24
type: Species
in compartment: COPASI2
initial amount: NaN
is: SBO:0000247
has only substance units: false
constant: false
initial concentration: 3.41E-5
is version of: CHEBI:16077
boundary condition: false
name: G1P

COPASI26
type: Species
in compartment: COPASI2
is version of: CHEBI:28087
initial concentration: 0.208403745497308
constant: true
name: GLY
is: SBO:0000247
has only substance units: false
initial amount: NaN
boundary condition: true

228138
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

228150
type: SpeciesReference
stoichiometry: 1.0
species: COPASI26

228174
type: SpeciesReference
stoichiometry: 2.0
species: COPASI25

228222
type: LocalParameter
value: 158.0
name: Kr

228210
type: LocalParameter
value: 267100.0
name: Keq

228198
type: LocalParameter
value: 17400.0
name: Kf

228162
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

225451
type: Parameter
constant: true
value: 4.0E-5
name: PGK_Kb

COPASI45
type: Parameter
constant: false
value: 49.2079666512274
name: TPI_Vr

COPASI113
type: Reaction
fast: false
reversible: false
reactant: 229050
kinetic law: 229086
modifier: 580738
product: 229062
is version of: GO:0016887
name: ATPase
product: 229074

229050
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

229098
type: LocalParameter
value: 6210.0
name: k1

229062
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

229074
type: SpeciesReference
stoichiometry: 1.0
species: COPASI25

225715
type: Parameter
constant: true
value: 1.0E-5
name: GAPDH_Knadh

COPASI66
type: Parameter
constant: false
value: 23.03
name: GLUT_Vf

COPASI93
type: Reaction
modifier: 579896
reversible: true
kinetic law: 227274
modifier: 579908
fast: false
is version of: GO:0004802
name: TKL2
product: 227250
reactant: 227238
modifier: 579920
reactant: 227226
modifier: 579884
product: 227262

227370
type: LocalParameter
value: 0.215
name: K7

227358
type: LocalParameter
value: 3.0E-10
name: K4

227346
type: LocalParameter
value: 0.0287
name: K5

227334
type: LocalParameter
value: 5.48E-8
name: K3

227322
type: LocalParameter
value: 0.122
name: K6

227310
type: LocalParameter
value: 3.055E-7
name: K2

227298
type: LocalParameter
value: 1.84E-9
name: K1

227286
type: LocalParameter
value: 29.7
name: Keq_TKL2

227250
type: SpeciesReference
stoichiometry: 1.0
species: COPASI18

227238
type: SpeciesReference
stoichiometry: 1.0
species: COPASI9

227226
type: SpeciesReference
stoichiometry: 1.0
species: COPASI16

227262
type: SpeciesReference
stoichiometry: 1.0
species: COPASI7

COPASI39
type: Parameter
constant: true
value: 0.001345
name: Ntot

COPASI107
type: Reaction
modifier: 580474
reversible: true
is version of: GO:0008443
kinetic law: 228582
modifier: 580510
reactant: 228534
modifier: 580522
modifier: 228570
product: 228546
product: 228558
modifier: 580486
modifier: 580498
name: PK
fast: false
reactant: 228522

228678
type: LocalParameter
value: 195172.0
name: Kapp

228666
type: LocalParameter
value: 10.0
name: Kpyr

228654
type: LocalParameter
value: 0.86
name: Katp

228642
type: LocalParameter
value: 4.0E-4
name: Kfbp

228630
type: LocalParameter
value: 2.5
name: Kiatp

228618
type: LocalParameter
value: 1.0
name: L

228606
type: LocalParameter
value: 0.014
name: Kpep

228594
type: LocalParameter
value: 0.4
name: Kadp

228534
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

228546
type: SpeciesReference
stoichiometry: 1.0
species: COPASI33

228558
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

COPASI32
type: Species
name: PEP
has only substance units: false
boundary condition: false
in compartment: COPASI2
is: SBO:0000247
is version of: CHEBI:18021
initial amount: NaN
constant: false
initial concentration: 5.79E-5

228522
type: SpeciesReference
stoichiometry: 1.0
species: COPASI32

COPASI31
type: Species
initial concentration: 4.98E-6
has only substance units: false
is: SBO:0000247
is version of: CHEBI:18117
initial amount: NaN
boundary condition: false
constant: false
name: PG2
in compartment: COPASI2

COPASI22
type: Species
boundary condition: true
is: SBO:0000247
is version of: CHEBI:16027
initial amount: NaN
constant: true
in compartment: COPASI2
name: AMP
has only substance units: false
initial concentration: 0.00311

225365
type: SBMLUnitsDef
unit: 225377
name: time

225377
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 60.0
kind: SECOND

COPASI36
type: Species
name: O2
has only substance units: false
is: SBO:0000247
is version of: CHEBI:26689
initial concentration: 6.5E-5
constant: true
in compartment: COPASI2
initial amount: NaN
boundary condition: true

COPASI49
type: Parameter
constant: false
value: 17486.5107913669
name: PGI_Vmr

COPASI98
type: Reaction
product: 227790
kinetic law: 227814
product: 227802
modifier: 580090
fast: false
reactant: 227778
is version of: GO:0097023
modifier: 580114
name: FBA
reversible: true
modifier: 580102

227790
type: SpeciesReference
stoichiometry: 1.0
species: COPASI18

227802
type: SpeciesReference
stoichiometry: 1.0
species: COPASI29

227778
type: SpeciesReference
stoichiometry: 1.0
species: COPASI8

COPASI74
type: Parameter
constant: false
value: 5.976
name: TPI_Vf

COPASI75
type: Parameter
constant: false
value: 109.1
name: GAPDH_Vf

COPASI69
type: Parameter
constant: false
value: 1.008
name: G6PDH_Vf

225739
type: Parameter
constant: true
value: 9.0E-5
name: GAPDH_Knad

COPASI100
type: Reaction
reactant: 227874
name: GAPDH
kinetic law: 227922
product: 227910
modifier: 580162
modifier: 580198
fast: false
reactant: 227886
product: 227898
modifier: 580174
is version of: GO:0004365
reactant: 227862
reversible: true
modifier: 580150
modifier: 580186

227874
type: SpeciesReference
stoichiometry: 1.0
species: COPASI21

227910
type: SpeciesReference
stoichiometry: 1.0
species: COPASI20

227886
type: SpeciesReference
stoichiometry: 1.0
species: COPASI25

227898
type: SpeciesReference
stoichiometry: 1.0
species: COPASI14

227862
type: SpeciesReference
stoichiometry: 1.0
species: COPASI18

COPASI52
type: Parameter
constant: true
value: 17.2
name: PGLM_Keq

COPASI79
type: Parameter
constant: false
value: 160.9
name: ENO_Vf

COPASI53
type: Parameter
constant: true
value: 1000.0
name: scale1e3

225835
type: Parameter
constant: true
value: 7.0E-5
name: LDH_Kq

225463
type: Parameter
constant: true
value: 6.0E-5
name: ENO_Kmp

COPASI85
type: Reaction
name: GLUT
is version of: GO:0015758
reactant: 226279
modifier: 579524
fast: false
product: 226291
reversible: true
modifier: 579512
kinetic law: 226303

226279
type: SpeciesReference
stoichiometry: 1.0
species: COPASI11

COPASI3
type: Species
initial concentration: 8.97E-4
boundary condition: false
is version of: CHEBI:17234
is: SBO:0000247
constant: false
initial amount: NaN
in compartment: COPASI2
name: GLC
has only substance units: false

226291
type: SpeciesReference
stoichiometry: 1.0
species: COPASI3

226339
type: LocalParameter
value: 0.0093
name: KGlc

226327
type: LocalParameter
value: 0.01
name: KGlc_e

226315
type: LocalParameter
value: 1.0
name: keq

COPASI86
type: Reaction
kinetic law: 226399
name: HK
fast: false
product: 226375
modifier: 579572
modifier: 579548
modifier: 579560
reactant: 226351
is version of: GO:0004396
reactant: 226363
reversible: true
modifier: 579536
product: 226387

226459
type: LocalParameter
value: 0.0035
name: Kq

226447
type: LocalParameter
value: 2.0E-5
name: Kp

226435
type: LocalParameter
value: 651.0
name: Kapp

226423
type: LocalParameter
value: 0.0011
name: Kb

226411
type: LocalParameter
value: 1.0E-4
name: Ka

226375
type: SpeciesReference
stoichiometry: 1.0
species: COPASI4

226351
type: SpeciesReference
stoichiometry: 1.0
species: COPASI3

226363
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

226387
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

225415
type: Parameter
constant: true
value: 1.3E-4
name: PGK_Kp

COPASI81
type: Parameter
constant: false
value: 340.3
name: LDH_Vf

COPASI40
type: Parameter
constant: false
value: 0.0177545693277311
name: GPa_Vr

225619
type: Parameter
constant: true
value: 0.015
name: GPb_KiGLYf

225799
type: Parameter
constant: true
value: 5.0E-5
name: PGI_Kf6p

225859
type: Parameter
constant: true
value: 3.0E-4
name: LDH_Kb

COPASI60
type: Parameter
constant: false
value: 179.83480680891
name: ENO_Vr

225655
type: Parameter
constant: true
value: 1.6E-4
name: FBA_Kg3p

225583
type: Parameter
constant: true
value: 0.01049
name: GPb_Vmaxf

COPASI112
type: Reaction
kinetic law: 229014
product: 228990
modifier: 580666
reactant: 228942
modifier: 580714
reversible: true
modifier: 580678
name: MPM
is version of: GO:0004739
reactant: 228978
reactant: 228966
modifier: 580690
reactant: 228954
modifier: 580726
fast: false
product: 229002
modifier: 580702

229038
type: LocalParameter
value: 1000000.0
name: Keq

229026
type: LocalParameter
value: 12.5
name: y

228990
type: SpeciesReference
stoichiometry: 0.24
species: COPASI35

COPASI35
type: Species
constant: true
in compartment: COPASI2
is version of: CHEBI:16526
has only substance units: false
is: SBO:0000247
initial concentration: 0.0214
name: CO2
initial amount: NaN
boundary condition: true

228942
type: SpeciesReference
stoichiometry: 0.08
species: COPASI33

228978
type: SpeciesReference
stoichiometry: 1.0
species: COPASI5

228966
type: SpeciesReference
stoichiometry: 1.0
species: COPASI25

228954
type: SpeciesReference
stoichiometry: 0.2
species: COPASI36

229002
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

225847
type: Parameter
constant: true
value: 2.0E-6
name: LDH_Ka

COPASI65
type: Parameter
constant: true
value: 1.0
name: AKT_MPM

COPASI92
type: Reaction
is version of: GO:0004802
reactant: 227082
modifier: 579872
modifier: 579860
reversible: true
kinetic law: 227118
fast: false
product: 227094
modifier: 579848
product: 227106
modifier: 579836
reactant: 227070
name: TKL

227082
type: SpeciesReference
stoichiometry: 1.0
species: COPASI16

227214
type: LocalParameter
value: 48.8
name: K7

227202
type: LocalParameter
value: 4.96E-9
name: K4

227190
type: LocalParameter
value: 0.41139
name: K5

227178
type: LocalParameter
value: 1.2432E-5
name: K3

227166
type: LocalParameter
value: 0.00774
name: K6

227154
type: LocalParameter
value: 3.055E-7
name: K2

227142
type: LocalParameter
value: 4.177E-7
name: K1

227130
type: LocalParameter
value: 2.08
name: Keq_TKL

227094
type: SpeciesReference
stoichiometry: 1.0
species: COPASI18

227106
type: SpeciesReference
stoichiometry: 1.0
species: COPASI19

COPASI17
type: Species
has only substance units: false
is: SBO:0000247
in compartment: COPASI2
initial concentration: 2.74E-5
boundary condition: false
initial amount: NaN
name: R5P
constant: false
is version of: CHEBI:58273

227070
type: SpeciesReference
stoichiometry: 1.0
species: COPASI17

COPASI106
type: Reaction
reversible: true
reactant: 228486
kinetic law: 228510
name: ENO
is version of: GO:0004634
modifier: 580462
product: 228498
modifier: 580450
fast: false

228486
type: SpeciesReference
stoichiometry: 1.0
species: COPASI31

228498
type: SpeciesReference
stoichiometry: 1.0
species: COPASI32

COPASI48
type: Parameter
constant: true
value: 0.0018
name: FBA_Keq

225571
type: Parameter
constant: true
value: 0.004
name: GPa_KPi

225427
type: Parameter
constant: true
value: 2.7E-4
name: PGK_Kq

COPASI96
type: Reaction
modifier: 580030
product: 227670
reactant: 227658
modifier: 580042
name: PGLM
fast: false
is version of: GO:0004614
kinetic law: 227682
reversible: true

227670
type: SpeciesReference
stoichiometry: 1.0
species: COPASI4

227658
type: SpeciesReference
stoichiometry: 1.0
species: COPASI24

COPASI73
type: Parameter
constant: false
value: 14.63
name: FBA_Vf

COPASI97
type: Reaction
reversible: true
product: 227718
reactant: 227694
fast: false
product: 227730
is version of: GO:0008184
modifier: 580078
modifier: 580066
reactant: 227706
name: GPa
modifier: 580054
kinetic law: 227742

227718
type: SpeciesReference
stoichiometry: 1.0
species: COPASI26

227694
type: SpeciesReference
stoichiometry: 1.0
species: COPASI26

227730
type: SpeciesReference
stoichiometry: 1.0
species: COPASI24

227706
type: SpeciesReference
stoichiometry: 1.0
species: COPASI25

227766
type: LocalParameter
value: 0.0047
name: KiPi

227754
type: LocalParameter
value: 1.5E-4
name: KGLYb

COPASI12
type: Species
has only substance units: false
initial concentration: 6.118E-7
boundary condition: true
initial amount: NaN
constant: false
is: SBO:0000247
name: NADP
is version of: CHEBI:25523
in compartment: COPASI2

COPASI78
type: Parameter
constant: false
value: 107.6
name: PFK_Vf

COPASI51
type: Parameter
constant: false
value: 0.203875968992248
name: PGLM_Vmr

225595
type: Parameter
constant: true
value: 0.0044
name: GPb_KiGLYb

COPASI56
type: Parameter
constant: true
value: 11.369
name: PGK_Keq

COPASI80
type: Parameter
constant: false
value: 27.81
name: PK_Vf

COPASI89
type: Reaction
name: PGDH
product: 226758
reactant: 226734
modifier: 579716
product: 226770
modifier: 579776
modifier: 579752
kinetic law: 226806
fast: false
modifier: 579728
modifier: 579764
modifier: 579740
reactant: 226746
reversible: true
modifier: 226794
modifier: 226782
is version of: GO:0017057

226758
type: SpeciesReference
stoichiometry: 1.0
species: COPASI15

226734
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

226770
type: SpeciesReference
stoichiometry: 1.0
species: COPASI13

226890
type: LocalParameter
value: 4.5E-9
name: KNADPH

226878
type: LocalParameter
value: 5.8E-8
name: K6PG2

226866
type: LocalParameter
value: 1.54E-7
name: KATP

226854
type: LocalParameter
value: 1.2E-7
name: KPGA23

226842
type: LocalParameter
value: 141.7
name: Kapp

226830
type: LocalParameter
value: 1.8E-8
name: KNADP

226818
type: LocalParameter
value: 1.0E-8
name: K6PG1

226746
type: SpeciesReference
stoichiometry: 1.0
species: COPASI12

225511
type: Parameter
constant: true
value: 6.3E-5
name: PGLM_KG1P

225811
type: Parameter
constant: true
value: 4.0E-4
name: PGI_Kg6p

W3 CDTF: Mon Sep 03 16:27:35 BST 2012

225787
type: Parameter
constant: true
value: 1.9E-4
name: PGYM_Kms

COPASI59
type: Parameter
constant: true
value: 1.4127
name: ENO_Keq

COPASI44
type: Parameter
constant: false
value: 11.5595061728395
name: FBA_Vr

COPASI111
type: Reaction
reactant: 228894
fast: false
reversible: true
product: 228906
kinetic law: 228918
name: DPHase
modifier: 580642
modifier: 580654
is version of: GO:0070995

228894
type: SpeciesReference
stoichiometry: 1.0
species: COPASI13

228906
type: SpeciesReference
stoichiometry: 1.0
species: COPASI12

228930
type: LocalParameter
value: 0.2
name: Keq

COPASI63
type: Parameter
constant: false
value: 0.00311
name: AMP

COPASI64
type: Parameter
constant: true
value: 1.0
name: AKT

COPASI91
type: Reaction
modifier: 579824
kinetic law: 227010
reactant: 226986
modifier: 579812
reversible: true
name: R5PI
is version of: GO:0004751
product: 226998
fast: false

227058
type: LocalParameter
value: 2.2E-6
name: KR5P

227046
type: LocalParameter
value: 7.8E-7
name: KRu5P

227034
type: LocalParameter
value: 3.0
name: Keq_R5PI

227022
type: LocalParameter
value: 0.7646
name: Vmax

226986
type: SpeciesReference
stoichiometry: 1.0
species: COPASI15

226998
type: SpeciesReference
stoichiometry: 1.0
species: COPASI17

COPASI105
type: Reaction
is version of: GO:0004619
modifier: 580426
kinetic law: 228474
modifier: 580438
fast: false
reversible: true
reactant: 228450
product: 228462
name: PGYM

228450
type: SpeciesReference
stoichiometry: 1.0
species: COPASI30

228462
type: SpeciesReference
stoichiometry: 1.0
species: COPASI31

W3 CDTF: Mon Jun 10 12:47:43 BST 2013

COPASI47
type: Parameter
constant: false
value: 71.7220990679741
name: PGK_Vr

225631
type: Parameter
constant: true
value: 0.0046
name: GPb_KiPi

COPASI95
type: Reaction
name: PRPPS
reactant: 227550
reversible: true
is version of: GO:0004749
modifier: 579982
fast: false
product: 227574
product: 227586
modifier: 579994
kinetic law: 227598
modifier: 580006
reactant: 227562
modifier: 580018

227550
type: SpeciesReference
stoichiometry: 1.0
species: COPASI17

227574
type: SpeciesReference
stoichiometry: 1.0
species: COPASI22

227586
type: SpeciesReference
stoichiometry: 1.0
species: COPASI23

COPASI23
type: Species
is version of: http://identifiers.org/pubchem.compound/7339
name: PRPP
constant: true
in compartment: COPASI2
has only substance units: false
initial concentration: 0.001
is: SBO:0000247
boundary condition: true
initial amount: NaN

227646
type: LocalParameter
value: 5.7E-7
name: KR5P

227634
type: LocalParameter
value: 3.0E-8
name: KATP

227622
type: LocalParameter
value: 100000.0
name: Kapp

227610
type: LocalParameter
value: 0.5104
name: Vmax

227562
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

COPASI68
type: Parameter
constant: false
value: 7778.0
name: PGI_Vmf

COPASI72
type: Parameter
constant: false
value: 0.1761
name: TKL2_Vf

COPASI109
type: Reaction
is version of: GO:0004017
reversible: true
modifier: 580606
product: 228786
product: 228798
modifier: 580582
reactant: 228774
fast: false
modifier: 580594
name: AK
kinetic law: 228810

228786
type: SpeciesReference
stoichiometry: 1.0
species: COPASI6

228798
type: SpeciesReference
stoichiometry: 1.0
species: COPASI22

228774
type: SpeciesReference
stoichiometry: 2.0
species: COPASI5

228834
type: LocalParameter
value: 2.26
name: Keq

228822
type: LocalParameter
value: 141.2
name: Vf

COPASI71
type: Parameter
constant: false
value: 1056.0
name: TKL_Vf

ORG:
  orgname: EMBL-EBI
n:
  given: Vijayalakshmi
  family: Chelliah

225823
type: Parameter
constant: true
value: 0.0047
name: LDH_Kp

COPASI77
type: Parameter
constant: false
value: 32040.0
name: GS_Vf

COPASI50
type: Parameter
constant: true
value: 0.0556
name: PGI_Keq

COPASI102
type: Reaction
product: 228054
is version of: GO:0008184
modifier: 580282
fast: false
name: GPb
modifier: 580258
reactant: 228018
modifier: 580270
kinetic law: 228066
reactant: 228030
product: 228042
reversible: true

228054
type: SpeciesReference
stoichiometry: 1.0
species: COPASI24

228018
type: SpeciesReference
stoichiometry: 1.0
species: COPASI26

228114
type: LocalParameter
value: 1.9E-12
name: Kamp

228102
type: LocalParameter
value: 1.75
name: nH

228090
type: LocalParameter
value: 0.0074
name: KiG1P

228078
type: LocalParameter
value: 2.0E-4
name: KPi

228030
type: SpeciesReference
stoichiometry: 1.0
species: COPASI25

228042
type: SpeciesReference
stoichiometry: 1.0
species: COPASI26

225547
type: Parameter
constant: true
value: 0.0101
name: GPa_KiG1P

225439
type: Parameter
constant: true
value: 7.9E-5
name: PGK_Ka

COPASI55
type: Parameter
constant: true
value: 0.3574
name: GAPDH_Keq

COPASI88
type: Reaction
reactant: 226578
name: G6PDH
kinetic law: 226650
modifier: 226638
fast: false
modifier: 579692
modifier: 226626
modifier: 579704
reactant: 226590
modifier: 579680
product: 226602
modifier: 579668
is version of: GO:0004345
modifier: 579656
modifier: 579644
reversible: true
product: 226614

226578
type: SpeciesReference
stoichiometry: 1.0
species: COPASI4

226722
type: LocalParameter
value: 2.289E-6
name: KPGA23

226710
type: LocalParameter
value: 3.12E-9
name: KNADPH

226698
type: LocalParameter
value: 7.49E-7
name: KATP

226686
type: LocalParameter
value: 2000.0
name: Kapp

226674
type: LocalParameter
value: 3.67E-9
name: KNADP

226662
type: LocalParameter
value: 6.67E-8
name: KG6P

226590
type: SpeciesReference
stoichiometry: 1.0
species: COPASI12

226602
type: SpeciesReference
stoichiometry: 1.0
species: COPASI10

226614
type: SpeciesReference
stoichiometry: 1.0
species: COPASI13

225475
type: Parameter
constant: true
value: 3.8E-5
name: ENO_Kms

225643
type: Parameter
constant: true
value: 8.0E-5
name: FBA_Kdhap

COPASI38
type: Parameter
constant: true
value: 1.932E-5
name: NPtot

COPASI84
type: Parameter
constant: false
value: 9801000.0
name: MPM_Vf

225535
type: Parameter
constant: true
value: 1.5E-4
name: GPa_KiGLYb

ORG:
  orgname: Institute for Biomedical Technologies, National Research Council
n:
  given: Ettore
  family: Mosca

ORG:
  orgname: ITB-CNR
n:
  given: Roberta
  family: Alfieri