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units def: metaid_0000321
reaction: metaid_0000217
reaction: metaid_0000311
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reaction: metaid_0000291
reaction: metaid_0000332
reaction: metaid_0000220
reaction: metaid_0000252
rule: metaid_0000463
parameter: metaid_0000170
reaction: metaid_0000236
species: blabla 6
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species: metaid_0000038
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reaction: metaid_0000303
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metaid_0000321
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260442
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metaid_0000217
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260770
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metaid_0000014
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metaid_0000005
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260758
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metaid_0000023
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260746
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metaid_0000012
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metaid_0000311
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is version of: GO:0043241
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265143
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metaid_0000065
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265131
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metaid_0000086
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265119
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metaid_0000089
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metaid_0000160
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metaid_0000324
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260478
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metaid_0000307
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264951
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metaid_0000082
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264939
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264927
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metaid_0000085
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metaid_0000176
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metaid_0000326
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260527
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260514
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metaid_0000094
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metaid_0000215
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is version of: MOD:00000
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260673
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metaid_0000010
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260661
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metaid_0000009
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is version of: REACT 9820
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metaid_0000207
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metaid_0000174
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units: metaid_0000326
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metaid_0000222
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260977
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metaid_0000015
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260965
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metaid_0000021
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260953
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metaid_0000011
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metaid_0000046
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metaid_0000004
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metaid_0000017
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metaid_0000323
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260466
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metaid_0000048
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metaid_0000291
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is version of: GO:0043241
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264181
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metaid_0000043
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264169
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metaid_0000022
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264157
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metaid_0000071
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metaid_0000332
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265754
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metaid_0000026
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265741
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265727
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metaid_0000095
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metaid_0000220
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260893
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metaid_0000020
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260881
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metaid_0000019
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260869
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metaid_0000252
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262345
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262332
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metaid_0000044
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262320
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metaid_0000029
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metaid_0000170
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metaid_0000236
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261582
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metaid_0000039
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261570
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metaid_0000038
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261558
type: SpeciesReference
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metaid_0000027
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blabla 6
type: Species
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initial concentration: NaN
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in compartment: metaid_0000005
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metaid_0000067
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metaid_0000289
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is version of: GO:0006461
fast: false
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name: v77

264085
type: SpeciesReference
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species: metaid_0000073

metaid_0000073
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264073
type: SpeciesReference
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264061
type: SpeciesReference
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metaid_0000076
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metaid_0000303
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is version of: GO:0043241
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264759
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metaid_0000058
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264747
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metaid_0000080
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264735
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metaid_0000083
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metaid_0000152
type: Parameter
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metaid_0000060
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metaid_0000197
type: Parameter
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metaid_0000168
type: Parameter
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metaid_0000301
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264661
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264649
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metaid_0000077
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264637
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metaid_0000081
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metaid_0000150
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metaid_0000195
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metaid_0000317
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265383
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metaid_0000024
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265371
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metaid_0000030
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metaid_0000166
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value: 6.871213E-4

metaid_0000137
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value: 3803.728

metaid_0000135
type: Parameter
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units: metaid_0000326
value: 5.174108E-4

metaid_0000098
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metaid_0000281
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263712
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metaid_0000068
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263700
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263687
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metaid_0000036
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metaid_0000091
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metaid_0000253
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kinetic law: 262406
product: 262394
reactant: 262381
reactant: 262369
is version of: GO:0006461
fast: false
reversible: true
name: v41

262394
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000040

metaid_0000040
type: Species
has part: P01133
has only substance units: true
has part: Q07889
in compartment: metaid_0000005
name: EGF-EGFR*^2-GAP-Shc*-Grb2-Sos
has part: P20936
has part: P00533
has part: P62993
has part: P98077
initial concentration: NaN
initial amount: 0.0
constant: false
boundary condition: false

262381
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000038

262369
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000035

metaid_0000035
type: Species
constant: false
has part: P62993
name: Grb2-Sos
initial concentration: NaN
in compartment: metaid_0000005
initial amount: 40000.0
has part: Q07889
boundary condition: false
has only substance units: true

metaid_0000297
type: Reaction
kinetic law: 264481
product: 264469
product: 264457
reactant: 264445
is version of: GO:0043241
fast: false
reversible: true
name: v85

264469
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000049

metaid_0000049
type: Species
is version of: MI:0501
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 40000.0
in compartment: metaid_0000005
name: Phosphotase1

264457
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000046

264445
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000078

metaid_0000078
type: Species
constant: false
boundary condition: false
initial concentration: NaN
in compartment: metaid_0000005
has part: P04049
has part: MI:0501
has only substance units: true
name: Rafi*-P'ase
initial amount: 0.0

metaid_0000269
type: Reaction
kinetic law: 263179
product: 263167
product: 263155
reactant: 263143
is version of: GO:0043241
fast: false
reversible: true
name: v57

263167
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000065

263155
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000062

metaid_0000062
type: Species
initial concentration: NaN
initial amount: 0.0
name: ERK-P
has only substance units: true
is version of: P28482
boundary condition: false
constant: false
in compartment: metaid_0000005
is version of: C00562

263143
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000066

metaid_0000066
type: Species
boundary condition: false
constant: false
has part: MI:0501
initial amount: 0.0
initial concentration: NaN
in compartment: metaid_0000005
is version of: C00562
has only substance units: true
name: ERK-PP-P'ase3
has part: P28482

metaid_0000144
type: Parameter
constant: true
units: metaid_0000326
value: 6.370566E-7

blabla 3
type: Species
constant: false
boundary condition: true
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: t_MEK_PP

metaid_0000295
type: Reaction
kinetic law: 264385
product: 264373
reactant: 264361
reactant: 264349
is version of: GO:0006461
fast: false
reversible: true
name: v83

264373
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000071

264361
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000069

metaid_0000069
type: Species
initial amount: 0.0
name: EGF-EGFRi*^2-GAP-Shc*
in compartment: metaid_0000005
has only substance units: true
initial concentration: NaN
boundary condition: false
has part: P00533
constant: false
has part: P20936
has part: P98077
has part: P01133

264349
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000035

metaid_0000007
type: Species
is version of: P00533
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 50000.0
in compartment: metaid_0000003
name: EGFR

metaid_0000003
type: Compartment
is: GO:0005615
constant: true
size: 1.0
spatial dimensions: 3.0
name: extracellular volume

metaid_0000189
type: Parameter
constant: true
units: metaid_0000324
value: 1.870396

metaid_0000267
type: Reaction
kinetic law: 263083
product: 263071
product: 263059
reactant: 263047
is version of: GO:0043241
fast: false
reversible: true
name: v55

263071
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000056

metaid_0000056
type: Species
has only substance units: true
initial amount: 0.0
name: MEK-PP
boundary condition: false
is version of: Q02750
initial concentration: NaN
constant: false
in compartment: metaid_0000005
is version of: C00562

263059
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000064

metaid_0000064
type: Species
in compartment: metaid_0000005
has only substance units: true
boundary condition: false
initial concentration: NaN
initial amount: 0.0
is version of: P28482
name: ERK-PP
is version of: C00562
constant: false

263047
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000063

metaid_0000063
type: Species
boundary condition: false
initial concentration: NaN
constant: false
name: ERK-P-MEK-PP
has part: Q02750
has part: P28482
initial amount: 0.0
in compartment: metaid_0000005
has only substance units: true
is version of: C00562

metaid_0000279
type: Reaction
kinetic law: 263627
product: 263615
reactant: 263603
reactant: 263591
is version of: GO:0006461
fast: false
reversible: true
name: v67

263615
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000026

263603
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000024

263591
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000076

metaid_0000084
type: Species
has only substance units: true
is version of: C00562
in compartment: metaid_0000005
name: MEKi-P-P'ase2i
has part: MI:0501
has part: Q02750
initial concentration: NaN
boundary condition: false
constant: false
initial amount: 0.0

metaid_0000142
type: Parameter
constant: true
units: metaid_0000324
value: 31.71871

metaid_0000053
type: Species
initial amount: 0.0
in compartment: metaid_0000005
has only substance units: true
boundary condition: false
constant: false
initial concentration: NaN
has part: P04049
has part: Q02750
name: MEK-Raf*

metaid_0000187
type: Parameter
constant: true
units: metaid_0000326
value: 0.001522817

metaid_0000158
type: Parameter
constant: true
units: metaid_0000326
value: 1.714441E-5

metaid_0000334
type: Reaction
kinetic law: 265858
product: 265845
reactant: 265832
reactant: 265819
is version of: GO:0006461
fast: false
reversible: true
name: v115

265845
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000096

metaid_0000096
type: Species
initial amount: 0.0
has only substance units: true
has part: P01133
name: EGF-EGFR*^2-GAP-Shc*-Grb2-Prot
boundary condition: false
has part: P98077
has part: P00533
has part: GO:0030119
has part: P20936
initial concentration: NaN
constant: false
in compartment: metaid_0000005
has part: P62993

265832
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

265819
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000039

metaid_0000129
type: Parameter
constant: true
units: metaid_0000326
value: 3.047285E-5

metaid_0000238
type: Reaction
kinetic law: 261691
product: 261679
reactant: 261667
reactant: 261655
is version of: GO:0006461
fast: false
reversible: true
name: v26

261679
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000041

metaid_0000041
type: Species
has part: P98077
in compartment: metaid_0000005
has part: CHEBI:17552
constant: false
initial amount: 0.0
has part: P00533
has part: P01112
has part: P62993
initial concentration: NaN
has part: P01133
has part: Q07889
name: EGF-EGFR*^2-GAP-Shc*-Grb2-Sos-Ras-GDP
boundary condition: false
has part: P20936
has only substance units: true

261667
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000040

261655
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

metaid_0000031
type: Species
initial concentration: NaN
name: Ras-GDP
boundary condition: false
constant: false
has only substance units: true
in compartment: metaid_0000005
has part: CHEBI:17552
has part: P01112
initial amount: 72000.0

metaid_0000074
type: Species
initial concentration: NaN
has only substance units: true
name: Rasi-GTP
in compartment: metaid_0000005
has part: P01112
has part: CHEBI:15996
constant: false
initial amount: 0.0
boundary condition: false

metaid_0000127
type: Parameter
constant: true
units: metaid_0000324
value: 31.71871

metaid_0000212
type: Parameter
constant: true
units: metaid_0000324
value: 0.006499143

metaid_0000261
type: Reaction
kinetic law: 262794
product: 262782
product: 262770
reactant: 262758
is version of: GO:0043241
fast: false
reversible: true
name: v49

262782
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000058

262770
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000054

metaid_0000054
type: Species
constant: false
initial amount: 0.0
is version of: Q02750
name: MEK-P
initial concentration: NaN
in compartment: metaid_0000005
is version of: C00562
has only substance units: true
is described by: http://identifiers.org/omim/176872
is version of: A4QPA9
boundary condition: false

262758
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000057

metaid_0000057
type: Species
initial concentration: NaN
in compartment: metaid_0000005
has only substance units: true
boundary condition: false
has part: Q9BZL4
has part: Q02750
name: MEK-PP-P'ase2
constant: false
is version of: C00562
initial amount: 0.0

metaid_0000273
type: Reaction
kinetic law: 263349
product: 263337
reactant: 263325
is version of: GO:0030163
fast: false
reversible: false
name: v61

263337
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000018

metaid_0000018
type: Species
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000004
name: EGFideg

263325
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000021

metaid_0000245
type: Reaction
kinetic law: 262032
product: 262020
product: 262008
reactant: 261996
is version of: GO:0043241
fast: false
reversible: true
name: v33

262020
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000035

262008
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000045

metaid_0000045
type: Species
has part: P98077
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: Shc*

261996
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000043

metaid_0000271
type: Reaction
kinetic law: 263277
product: 263265
product: 263253
reactant: 263241
is version of: GO:0043241
fast: false
reversible: true
name: v59

263265
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000065

263253
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000060

263241
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000067

metaid_0000308
type: Reaction
kinetic law: 265011
product: 264999
reactant: 264987
reactant: 264975
is version of: GO:0006461
fast: false
reversible: true
name: v96

264999
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000087

metaid_0000087
type: Species
boundary condition: false
in compartment: metaid_0000005
has part: Q02750
has only substance units: true
initial amount: 0.0
is version of: C00562
name: ERKi-P-MEKi-PP
constant: false
has part: P28482
initial concentration: NaN

264987
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000086

264975
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000082

metaid_0000028
type: Species
has part: P20936
boundary condition: false
constant: false
name: EGF-EGFR*^2-GAP-Grb2
has part: P00533
has part: P01133
in compartment: metaid_0000005
has part: P62993
initial amount: 0.0
initial concentration: NaN
has only substance units: true

metaid_0000243
type: Reaction
kinetic law: 261934
product: 261922
product: 261910
reactant: 261898
is version of: GO:0043241
fast: false
reversible: true
name: v31

261922
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

261910
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000040

261898
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

metaid_0000042
type: Species
has part: CHEBI:15996
boundary condition: false
has part: P01112
has part: P01133
has only substance units: true
name: EGF-EGFR*^2-GAP-Shc*-Grb2-Sos-Ras-GTP
has part: Q07889
in compartment: metaid_0000005
has part: P00533
has part: P20936
has part: P62993
has part: P98077
initial concentration: NaN
constant: false
initial amount: 0.0

metaid_0000287
type: Reaction
kinetic law: 264000
product: 263988
reactant: 263976
reactant: 263964
is version of: GO:0006461
fast: false
reversible: true
name: v75

263988
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000075

metaid_0000075
type: Species
has only substance units: true
has part: P01112
initial concentration: NaN
has part: P04049
name: Rafi-Rasi-GTP
boundary condition: false
constant: false
initial amount: 0.0
in compartment: metaid_0000005
has part: CHEBI:15996

263976
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000046

263964
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000074

metaid_0000259
type: Reaction
kinetic law: 262697
product: 262685
product: 262673
reactant: 262661
is version of: GO:0043241
fast: false
reversible: true
name: v47

262685
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

metaid_0000050
type: Species
is version of: P04049
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: Raf*

262673
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000056

262661
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000055

metaid_0000055
type: Species
initial amount: 0.0
in compartment: metaid_0000005
has only substance units: true
boundary condition: false
has part: P04049
has part: Q02750
is version of: C00562
constant: false
name: MEK-P-Raf*
initial concentration: NaN

metaid_0000013
type: Species
name: EGF-EGFRi*^2
has only substance units: true
has part: P00533
has part: P01133
boundary condition: false
constant: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005

metaid_0000310
type: Reaction
kinetic law: 265107
product: 265095
reactant: 265083
reactant: 265071
is version of: GO:0006461
fast: false
reversible: true
name: v98

265095
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000089

265083
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000065

265071
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000088

metaid_0000088
type: Species
name: ERKi-PP
initial amount: 0.0
is version of: C00562
initial concentration: NaN
boundary condition: false
is version of: P28482
in compartment: metaid_0000005
constant: false
has only substance units: true

metaid_0000306
type: Reaction
kinetic law: 264915
product: 264903
reactant: 264891
reactant: 264879
is version of: GO:0006461
fast: false
reversible: true
name: v94

264903
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000085

264891
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000082

264879
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000060

metaid_0000214
type: Reaction
kinetic law: 260649
product: 260637
reactant: 260625
is version of: GO:0042803
fast: false
reversible: true
name: v2

260637
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000009

260625
type: SpeciesReference
stoichiometry: 2.0
species: metaid_0000008

metaid_0000008
type: Species
boundary condition: false
has only substance units: true
name: EGF-EGFR
initial amount: 0.0
constant: false
initial concentration: NaN
has part: P00533
in compartment: metaid_0000005
has part: P01133
is version of: REACT 9893

metaid_0000206
type: Parameter
constant: true
units: metaid_0000326
value: 0.004700229

blabla 2
type: Species
constant: false
boundary condition: true
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: t_Ras_GTP

metaid_0000322
type: SBMLUnitsDef
unit: 260454
name: min

260454
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 60.0
kind: SECOND

metaid_0000173
type: Parameter
constant: true
units: metaid_0000324
value: 10.96212

metaid_0000292
type: Reaction
kinetic law: 264241
product: 264229
product: 264217
reactant: 264205
is version of: GO:0043241
fast: false
reversible: true
name: v80

264229
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000035

264217
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

264205
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000024

metaid_0000204
type: Parameter
constant: true
units: metaid_0000324
value: 1120.398

metaid_0000228
type: Reaction
kinetic law: 261218
product: 261206
reactant: 261194
reactant: 261182
is version of: GO:0006461
fast: false
reversible: true
name: v16

261206
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000028

261194
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

261182
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000027

metaid_0000221
type: Reaction
kinetic law: 260941
product: 260929
reactant: 260917
is version of: MOD:00000
fast: false
reversible: false
name: v9

260929
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000023

260917
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000028

metaid_0000171
type: Parameter
constant: true
units: metaid_0000326
value: 5.54527E-5

metaid_0000059
type: Species
in compartment: metaid_0000005
initial amount: 0.0
initial concentration: NaN
is version of: C00562
has only substance units: true
has part: Q02750
constant: false
boundary condition: false
name: MEK-P-P'ase2
has part: Q9BZL4

metaid_0000290
type: Reaction
kinetic law: 264145
product: 264133
product: 264121
reactant: 264109
is version of: GO:0043241
fast: false
reversible: true
name: v78

264133
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

264121
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000071

264109
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000073

metaid_0000331
type: Reaction
kinetic law: 265714
product: 265701
reactant: 265688
reactant: 265675
is version of: GO:0006461
fast: false
reversible: true
name: v112

265701
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000095

265688
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

265675
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000034

metaid_0000034
type: Species
has part: Q07889
has only substance units: true
initial concentration: NaN
in compartment: metaid_0000005
name: EGF-EGFR*^2-GAP-Grb2-Sos-Ras-GTP
initial amount: 0.0
has part: CHEBI:15996
has part: P62993
has part: P00533
has part: P01133
has part: P20936
has part: P01112
constant: false
boundary condition: false

metaid_0000251
type: Reaction
kinetic law: 262308
product: 262296
product: 262284
reactant: 262272
is version of: GO:0043241
fast: false
reversible: true
name: v39

262296
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000044

262284
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

262272
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000039

metaid_0000235
type: Reaction
kinetic law: 261546
product: 261533
reactant: 261521
is version of: GO:0006461
fast: false
reversible: true
name: v23

261533
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000038

261521
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000037

metaid_0000037
type: Species
in compartment: metaid_0000005
initial amount: 0.0
has part: P00533
boundary condition: false
constant: false
has only substance units: true
has part: P98077
name: EGF-EGFR*^2-GAP-Shc
initial concentration: NaN
has part: P01133
has part: P20936

metaid_0000025
type: Species
has part: CHEBI:17552
has part: P01112
has part: P00533
has part: P20936
in compartment: metaid_0000005
has part: P62993
initial amount: 0.0
initial concentration: NaN
has only substance units: true
boundary condition: false
name: EGF-EGFRi*^2-GAP-Grb2-Sos-Ras-GDP
has part: P01133
constant: false
has part: Q07889

metaid_0000302
type: Reaction
kinetic law: 264723
product: 264711
reactant: 264699
reactant: 264686
is version of: GO:0006461
fast: false
reversible: true
name: v90

264711
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000083

264699
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000058

264686
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000082

metaid_0000196
type: Parameter
constant: true
units: metaid_0000326
value: 6.874119E-4

metaid_0000300
type: Reaction
kinetic law: 264625
product: 264613
reactant: 264601
reactant: 264589
is version of: GO:0006461
fast: false
reversible: true
name: v88

264613
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000081

264601
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000080

264589
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000077

metaid_0000092
type: Species
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: EGF-EGFRi*^2deg

metaid_0000194
type: Parameter
constant: true
units: metaid_0000324
value: 1632.425

metaid_0000316
type: Reaction
kinetic law: 265359
product: 265347
reactant: 265335
is version of: MOD:00000
fast: false
reversible: true
name: v104

265347
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000069

265335
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000038

metaid_0000165
type: Parameter
constant: true
units: metaid_0000324
value: 1.218132

metaid_0000136
type: Parameter
constant: true
units: metaid_0000324
value: 0.9058936

metaid_0000033
type: Species
name: Ras-GTP
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
has part: P01112
has part: CHEBI:15996
constant: false
boundary condition: false

metaid_0000325
type: SBMLUnitsDef
unit: 260502
unit: 260490
name: itemspermin

260502
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND

260490
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 1.0
kind: ITEM

metaid_0000163
type: Parameter
constant: true
units: metaid_0000326
value: 0.007178843

metaid_0000192
type: Parameter
constant: true
units: metaid_0000326
value: 0.001406622

metaid_0000134
type: Parameter
constant: true
units: metaid_0000324
value: 0.003011324

metaid_0000351
type: Parameter
constant: false
value: NaN
name: C_internalization

metaid_0000327
type: SBMLUnitsDef
unit: 260564
unit: 260552
unit: 260539
name: plperitempermin

260564
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND

260552
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: ITEM

260539
type: SBMLUnit
exponent: 1.0
scale: -12
multipler: 1.0
kind: LITRE

metaid_0000190
type: Parameter
constant: true
units: metaid_0000324
value: 51.60945

W3 CDTF: Thu Nov 03 14:33:48 GMT 2011

metaid_0000294
type: Reaction
kinetic law: 264337
product: 264325
product: 264313
reactant: 264301
is version of: GO:0043241
fast: false
reversible: true
name: v82

264325
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000044

264313
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

264301
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000070

metaid_0000070
type: Species
in compartment: metaid_0000005
has part: P62993
name: EGF-EGFRi*^2-GAP-Shc*-Grb2
initial concentration: NaN
constant: false
has part: P20936
boundary condition: false
has part: P98077
has only substance units: true
has part: P00533
has part: P01133
initial amount: 0.0

metaid_0000188
type: Parameter
constant: true
units: metaid_0000326
value: 0.009688174

metaid_0000266
type: Reaction
kinetic law: 263035
product: 263023
reactant: 263011
reactant: 262999
is version of: GO:0006461
fast: false
reversible: true
name: v54

263023
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000063

263011
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000062

262999
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000056

metaid_0000278
type: Reaction
kinetic law: 263578
product: 263566
product: 263554
reactant: 263542
is version of: GO:0043241
fast: false
reversible: true
name: v66

263566
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000024

263554
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000074

263542
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000025

metaid_0000141
type: Parameter
constant: true
units: metaid_0000324
value: 2.220991

metaid_0000186
type: Parameter
constant: true
units: metaid_0000324
value: 44.60169

metaid_0000157
type: Parameter
constant: true
units: metaid_0000324
value: 0.4722901

metaid_0000128
type: Parameter
constant: true
units: metaid_0000324
value: 2.220991

metaid_0000237
type: Reaction
kinetic law: 261643
product: 261630
reactant: 261618
reactant: 261606
is version of: GO:0006461
fast: false
reversible: true
name: v25

261630
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000040

261618
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000039

261606
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000029

metaid_0000155
type: Parameter
constant: true
units: metaid_0000324
value: 12.816

metaid_0000126
type: Parameter
constant: true
units: metaid_0000326
value: 4.80156E-4

metaid_0000061
type: Species
has only substance units: true
is version of: C00562
has part: P28482
boundary condition: false
name: ERK-MEK-PP
initial amount: 0.0
in compartment: metaid_0000005
has part: Q02750
constant: false
initial concentration: NaN

metaid_0000211
type: Parameter
constant: true
units: metaid_0000324
value: 0.08693199

metaid_0000270
type: Reaction
kinetic law: 263228
product: 263216
reactant: 263204
reactant: 263192
is version of: GO:0006461
fast: false
reversible: true
name: v58

263216
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000067

263204
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000062

263192
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000065

metaid_0000242
type: Reaction
kinetic law: 261886
product: 261874
reactant: 261862
reactant: 261850
is version of: GO:0006461
fast: false
reversible: true
name: v30

261874
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

261862
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000048

261850
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000040

metaid_0000286
type: Reaction
kinetic law: 263952
product: 263940
product: 263928
reactant: 263916
is version of: GO:0043241
fast: false
reversible: true
name: v74

263940
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000074

263928
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000071

263916
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000072

metaid_0000072
type: Species
initial concentration: NaN
has part: Q07889
has only substance units: true
has part: P00533
name: EGF-EGFRi*^2-GAP-Shc*-Grb2-Sos-Ras-GDP
in compartment: metaid_0000005
has part: P01133
has part: P62993
has part: P01112
has part: P98077
has part: CHEBI:17552
has part: P20936
boundary condition: false
constant: false
initial amount: 0.0

metaid_0000258
type: Reaction
kinetic law: 262649
product: 262637
reactant: 262625
reactant: 262613
is version of: GO:0006461
fast: false
reversible: true
name: v46

262637
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000055

262625
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

262613
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000054

metaid_0000284
type: Reaction
kinetic law: 263856
product: 263844
reactant: 263832
reactant: 263820
is version of: GO:0006461
fast: false
reversible: true
name: v72

263844
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000071

263832
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000070

263820
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000029

metaid_0000149
type: Parameter
constant: true
units: metaid_0000324
value: 2.524092

metaid_0000256
type: Reaction
kinetic law: 262553
product: 262541
reactant: 262529
reactant: 262517
is version of: GO:0006461
fast: false
reversible: true
name: v44

262541
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000053

262529
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

262517
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000052

metaid_0000052
type: Species
in compartment: metaid_0000005
initial amount: 2.2E7
has only substance units: true
boundary condition: false
initial concentration: NaN
is described by: http://identifiers.org/omim/176872
is version of: Q02750
is version of: A4QPA9
constant: false
name: MEK

metaid_0000213
type: Reaction
kinetic law: 260613
product: 260601
reactant: 260589
reactant: 260577
is version of: GO:0006461
fast: false
reversible: true
name: v1

260601
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000008

260589
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000007

260577
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000006

metaid_0000006
type: Species
name: EGF
initial concentration: NaN
notes: 4962 molecules correspond roughly to 50 ng/ml, concentration used throughout the article (MW~6045 Da, vol=1e-12l) Similarly, 496.2 molecules correspond roughly to 5 ng/ml, 49.62 molecules correspond roughly to .5 ng/ml, 12.405 molecules correspond roughly to 0.125 ng/ml, 6.2025 molecules correspond roughly to 0.0625 ng/ml
in compartment: metaid_0000003
boundary condition: true
is version of: P01133
has only substance units: true
constant: false
initial amount: 4962.0

metaid_0000205
type: Parameter
constant: true
units: metaid_0000324
value: 1.229629

metaid_0000229
type: Reaction
kinetic law: 261267
product: 261255
reactant: 261243
reactant: 261230
is version of: GO:0006461
fast: false
reversible: true
name: v17

261255
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030

261243
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000028

261230
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000029

metaid_0000147
type: Parameter
constant: true
units: metaid_0000324
value: 0.4509308

metaid_0000172
type: Parameter
constant: true
units: metaid_0000324
value: 14.19908

metaid_0000203
type: Parameter
constant: true
units: metaid_0000324
value: 62181.84

metaid_0000339
type: Reaction
kinetic law: 266092
product: 266079
reactant: 266066
is version of: MOD:00000
fast: false
reversible: true
name: v120

266079
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000072

266066
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000041

metaid_0000099
type: Species
has part: P01112
initial amount: 0.0
has part: P01133
initial concentration: NaN
constant: false
has part: CHEBI:15996
has part: P62993
has part: P98077
has part: P00533
has part: GO:0030119
has part: P20936
has only substance units: true
name: EGF-EGFR*^2-GAP-Shc*-Grb2-Sos-Ras-GTP-Prot
in compartment: metaid_0000005
boundary condition: false
has part: Q07889

metaid_0000227
type: Reaction
kinetic law: 261170
product: 261158
reactant: 261146
is version of: MOD:00000
fast: false
reversible: false
name: v15

261158
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

261146
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

metaid_0000337
type: Reaction
kinetic law: 266001
product: 265988
reactant: 265975
reactant: 265962
is version of: GO:0006461
fast: false
reversible: true
name: v118

265988
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000097

metaid_0000097
type: Species
in compartment: metaid_0000005
has part: P62993
has part: P98077
has part: Q07889
has only substance units: true
boundary condition: false
has part: P20936
constant: false
name: EGF-EGFR*^2-GAP-Shc*-Grb2-Sos-Prot
has part: P00533
initial amount: 0.0
has part: GO:0030119
has part: P01133
initial concentration: NaN

265975
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

265962
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000040

metaid_0000330
type: Reaction
kinetic law: 265662
product: 265650
reactant: 265638
is version of: MOD:00000
fast: false
reversible: true
name: v111

265650
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000026

265638
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000034

metaid_0000250
type: Reaction
kinetic law: 262260
product: 262248
reactant: 262236
reactant: 262224
is version of: GO:0006461
fast: false
reversible: true
name: v38

262248
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000044

262236
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000045

262224
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000027

metaid_0000234
type: Reaction
kinetic law: 261509
product: 261497
reactant: 261485
reactant: 261473
is version of: GO:0006461
fast: false
reversible: true
name: v22

261497
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000037

261485
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

261473
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000036

blabla 4
type: Species
constant: false
boundary condition: true
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: t_ERK_PP

metaid_0000344
type: Reaction
kinetic law: 266333
product: 266321
product: 266309
reactant: 266297
is version of: GO:0043241
fast: false
reversible: true
name: v125

266321
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

266309
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000073

266297
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000099

metaid_0000264
type: Reaction
kinetic law: 262938
product: 262926
reactant: 262914
reactant: 262902
is version of: GO:0006461
fast: false
reversible: true
name: v52

262926
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000061

262914
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000056

262902
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000060

metaid_0000232
type: Reaction
kinetic law: 261413
product: 261401
reactant: 261388
reactant: 261376
is version of: GO:0006461
fast: false
reversible: true
name: v20

261401
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000034

261388
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000048

261376
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030

metaid_0000276
type: Reaction
kinetic law: 263482
product: 263470
reactant: 263458
reactant: 263446
is version of: GO:0006461
fast: false
reversible: true
name: v64

263470
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000024

263458
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000023

263446
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000029

metaid_0000248
type: Reaction
kinetic law: 262164
product: 262152
reactant: 262140
is version of: MOD:00000
fast: false
reversible: false
name: v36

262152
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000036

262140
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000045

metaid_0000193
type: Parameter
constant: true
units: metaid_0000324
value: 6340.081

metaid_0000315
type: Reaction
kinetic law: 265323
product: 265311
reactant: 265299
is version of: MOD:00000
fast: false
reversible: true
name: v103

265311
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000068

265299
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000037

metaid_0000164
type: Parameter
constant: true
units: metaid_0000324
value: 563.2135

metaid_0000219
type: Reaction
kinetic law: 260857
product: 260845
reactant: 260833
is version of: MOD:00000
fast: false
reversible: false
name: v7

260845
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000013

260833
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000010

metaid_0000313
type: Reaction
kinetic law: 265251
product: 265239
product: 265227
reactant: 265215
is version of: GO:0043241
fast: false
reversible: true
name: v101

265239
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000065

265227
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000060

265215
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000090

metaid_0000090
type: Species
in compartment: metaid_0000005
has only substance units: true
initial amount: 0.0
constant: false
boundary condition: false
has part: MI:0501
initial concentration: NaN
has part: P28482
name: ERKi-P-P'ase3i
is version of: C00562

metaid_0000162
type: Parameter
constant: true
units: metaid_0000324
value: 17.39321

metaid_0000191
type: Parameter
constant: true
units: metaid_0000324
value: 0.5985189

metaid_0000133
type: Parameter
constant: true
units: metaid_0000324
value: 0.294324

metaid_0000329
type: Reaction
kinetic law: 265625
product: 265612
product: 265599
reactant: 265587
is version of: GO:0043241
fast: false
reversible: true
name: v110

265612
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000025

265599
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

265587
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000094

metaid_0000178
type: Parameter
constant: true
units: metaid_0000326
value: 3.866434E-4

ORG:
  orgname: Whitaker Biomedical Engineering Institute, The Johns Hopkins University, Baltimore, MD 21218, USA
n:
  given: Garrett
  family: Jenkinson

metaid_0000131
type: Parameter
constant: false
units: metaid_0000324
value: NaN

metaid_0000320
type: Reaction
kinetic law: 265527
product: 265515
reactant: 265503
is version of: MOD:00000
fast: false
reversible: true
name: v108

265515
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000025

265503
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000032

metaid_0000032
type: Species
initial concentration: NaN
in compartment: metaid_0000005
has part: P62993
has part: P00533
initial amount: 0.0
has part: P01133
has part: CHEBI:17552
has part: P20936
has part: P01112
boundary condition: false
name: EGF-EGFR*^2-GAP-Grb2-Sos-Ras-GDP
has part: Q07889
constant: false
has only substance units: true

metaid_0000240
type: Reaction
kinetic law: 261789
product: 261777
reactant: 261765
reactant: 261753
is version of: GO:0006461
fast: false
reversible: true
name: v28

261777
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000047

metaid_0000047
type: Species
initial amount: 0.0
boundary condition: false
initial concentration: NaN
constant: false
has only substance units: true
has part: P04049
name: Raf-Ras-GTP
has part: CHEBI:15996
has part: P01112
in compartment: metaid_0000005

261765
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000046

261753
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000033

metaid_0000224
type: Reaction
kinetic law: 261062
product: 261050
reactant: 261038
is version of: MOD:00000
fast: false
reversible: true
name: v12

261050
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000013

261038
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000016

metaid_0000016
type: Species
boundary condition: false
name: EGF-EGFRi^2
constant: false
in compartment: metaid_0000005
initial amount: 0.0
has part: P00533
has part: P01133
has only substance units: true
initial concentration: NaN

metaid_0000293
type: Reaction
kinetic law: 264289
product: 264277
product: 264265
reactant: 264253
is version of: GO:0043241
fast: false
reversible: true
name: v81

264277
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000045

264265
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

264253
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000069

metaid_0000265
type: Reaction
kinetic law: 262987
product: 262974
product: 262962
reactant: 262950
is version of: GO:0043241
fast: false
reversible: true
name: v53

262974
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000062

262962
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000056

262950
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000061

metaid_0000277
type: Reaction
kinetic law: 263530
product: 263518
reactant: 263506
reactant: 263494
is version of: GO:0006461
fast: false
reversible: true
name: v65

263518
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000025

263506
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000024

263494
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

metaid_0000140
type: Parameter
constant: true
units: metaid_0000326
value: 4.80156E-4

metaid_0000051
type: Species
has part: P04049
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: Raf*-P'ase

metaid_0000185
type: Parameter
constant: true
units: metaid_0000324
value: 2.748877

metaid_0000156
type: Parameter
constant: true
units: metaid_0000326
value: 5.17656E-5

metaid_0000183
type: Parameter
constant: true
units: metaid_0000326
value: 5.477036E-6

metaid_0000305
type: Reaction
kinetic law: 264867
product: 264855
product: 264843
reactant: 264831
is version of: GO:0043241
fast: false
reversible: true
name: v93

264855
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000058

264843
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000052

264831
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000084

metaid_0000154
type: Parameter
constant: true
units: metaid_0000324
value: 349.772

metaid_0000125
type: Parameter
constant: true
units: metaid_0000324
value: 0.5100538

metaid_0000199
type: Parameter
constant: true
units: metaid_0000326
value: 5.464454E-4

metaid_0000210
type: Parameter
constant: true
units: metaid_0000324
value: 6.409354

metaid_0000181
type: Parameter
constant: true
units: metaid_0000321
value: 7.719778E14

metaid_0000123
type: Parameter
constant: true
units: metaid_0000326
value: 0.002372521

metaid_0000079
type: Species
constant: false
has part: P04049
name: MEKi-Rafi*
initial amount: 0.0
boundary condition: false
initial concentration: NaN
in compartment: metaid_0000005
has part: Q02750
has only substance units: true

metaid_0000139
type: Parameter
constant: true
units: metaid_0000324
value: 0.5100538

metaid_0000241
type: Reaction
kinetic law: 261837
product: 261825
product: 261813
reactant: 261801
is version of: GO:0043241
fast: false
reversible: true
name: v29

261825
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

261813
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000048

261801
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000047

metaid_0000285
type: Reaction
kinetic law: 263904
product: 263892
reactant: 263880
reactant: 263868
is version of: GO:0006461
fast: false
reversible: true
name: v73

263892
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000072

263880
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000071

263868
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

metaid_0000257
type: Reaction
kinetic law: 262601
product: 262589
product: 262577
reactant: 262565
is version of: GO:0043241
fast: false
reversible: true
name: v45

262589
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

262577
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000054

262565
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000053

metaid_0000283
type: Reaction
kinetic law: 263808
product: 263796
reactant: 263784
reactant: 263772
is version of: GO:0006461
fast: false
reversible: true
name: v71

263796
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000070

263784
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000069

263772
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000027

metaid_0000255
type: Reaction
kinetic law: 262505
product: 262493
product: 262481
reactant: 262468
is version of: GO:0006461
fast: false
reversible: true
name: v43

262493
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000049

262481
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000046

262468
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000051

metaid_0000093
type: Species
constant: false
has part: P01133
has part: Q07889
has part: P00533
in compartment: metaid_0000005
has part: GO:0030119
has part: P62993
name: EGF-EGFR*^2-GAP-Grb2-Sos-Prot
has only substance units: true
has part: P20936
boundary condition: false
initial concentration: NaN
initial amount: 0.0

metaid_0000148
type: Parameter
constant: true
units: metaid_0000326
value: 4.021305E-4

metaid_0000299
type: Reaction
kinetic law: 264577
product: 264565
product: 264553
reactant: 264541
is version of: GO:0043241
fast: false
reversible: true
name: v87

264565
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000077

264553
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000080

264541
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000079

metaid_0000146
type: Parameter
constant: true
units: metaid_0000324
value: 46468.78

blabla 5
type: Species
constant: false
boundary condition: true
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: t_SHC_P_t

metaid_0000318
type: Reaction
kinetic law: 265443
product: 265431
reactant: 265419
reactant: 265407
is version of: GO:0006461
fast: false
reversible: true
name: v106

265431
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000093

265419
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

265407
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030

metaid_0000202
type: Parameter
constant: true
units: metaid_0000324
value: 19.85279

metaid_0000338
type: Reaction
kinetic law: 266053
product: 266040
product: 266027
reactant: 266014
is version of: GO:0043241
fast: false
reversible: true
name: v119

266040
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000071

266027
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

266014
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000097

metaid_0000226
type: Reaction
kinetic law: 261134
product: 261122
reactant: 261110
reactant: 261098
is version of: GO:0006461
fast: false
reversible: true
name: v14

261122
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

261110
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000019

261098
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000013

metaid_0000336
type: Reaction
kinetic law: 265949
product: 265936
reactant: 265923
is version of: MOD:00000
fast: false
reversible: true
name: v117

265936
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000071

265923
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000040

metaid_0000233
type: Reaction
kinetic law: 261461
product: 261449
product: 261437
reactant: 261425
is version of: GO:0043241
fast: false
reversible: true
name: v21

261449
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

261437
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030

261425
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000034

metaid_0000343
type: Reaction
kinetic law: 266285
product: 266272
reactant: 266260
reactant: 266248
is version of: GO:0006461
fast: false
reversible: true
name: v124

266272
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000099

266260
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

266248
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

metaid_0000231
type: Reaction
kinetic law: 261364
product: 261352
product: 261339
reactant: 261327
is version of: GO:0043241
fast: false
reversible: true
name: v19

261352
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030

261339
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000033

261327
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000032

metaid_0000263
type: Reaction
kinetic law: 262890
product: 262878
product: 262866
reactant: 262854
is version of: GO:0043241
fast: false
reversible: true
name: v51

262878
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000058

262866
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000052

262854
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000059

metaid_0000275
type: Reaction
kinetic law: 263434
product: 263421
reactant: 263409
reactant: 263397
is version of: GO:0006461
fast: false
reversible: true
name: v63

263421
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000023

263409
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000027

263397
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

metaid_0000247
type: Reaction
kinetic law: 262128
product: 262116
product: 262104
reactant: 262092
is version of: GO:0043241
fast: false
reversible: true
name: v35

262116
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000027

262104
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000029

262092
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000035

metaid_0000341
type: Reaction
kinetic law: 266197
product: 266184
product: 266171
reactant: 266157
is version of: GO:0043241
fast: false
reversible: true
name: v122

266184
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000072

266171
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

266157
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000098

metaid_0000314
type: Reaction
kinetic law: 265287
product: 265275
reactant: 265263
is version of: MOD:00000
fast: false
reversible: true
name: v102

265275
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

265263
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

metaid_0000218
type: Reaction
kinetic law: 260820
product: 260808
reactant: 260795
is version of: MOD:00000
fast: false
reversible: true
name: v6

260808
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000011

260795
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000007

metaid_0000312
type: Reaction
kinetic law: 265203
product: 265191
reactant: 265179
reactant: 265167
is version of: GO:0006461
fast: false
reversible: true
name: v100

265191
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000090

265179
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000086

265167
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000065

metaid_0000161
type: Parameter
constant: true
units: metaid_0000324
value: 420.3359

metaid_0000132
type: Parameter
constant: true
units: metaid_0000324
value: 4.123214E-4

metaid_0000328
type: Reaction
kinetic law: 265575
product: 265563
reactant: 265551
reactant: 265539
is version of: GO:0006461
fast: false
reversible: true
name: v109

265563
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000094

265551
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

265539
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000032

metaid_0000177
type: Parameter
constant: true
units: metaid_0000324
value: 1.836058

metaid_0000216
type: Reaction
kinetic law: 260734
product: 260722
reactant: 260710
reactant: 260697
is version of: GO:0006461
fast: false
reversible: true
name: v4

260722
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000012

260710
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

260697
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000028

metaid_0000208
type: Parameter
constant: true
units: metaid_0000324
value: 0.1138168

metaid_0000130
type: Parameter
constant: true
units: metaid_0000324
value: 0.1230832

metaid_0000175
type: Parameter
constant: true
units: metaid_0000324
value: 0.2467995

metaid_0000223
type: Reaction
kinetic law: 261026
product: 261013
reactant: 261001
is version of: GO:0042803
fast: false
reversible: true
name: v11

261013
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000016

261001
type: SpeciesReference
stoichiometry: 2.0
species: metaid_0000015

W3 CDTF: Wed May 16 15:31:52 BST 2012

metaid_0000333
type: Reaction
kinetic law: 265806
product: 265793
reactant: 265780
is version of: MOD:00000
fast: false
reversible: true
name: v114

265793
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000070

265780
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000039

metaid_0000184
type: Parameter
constant: true
units: metaid_0000326
value: 7.409959E-5

metaid_0000182
type: Parameter
constant: true
units: metaid_0000324
value: 29.34687

metaid_0000304
type: Reaction
kinetic law: 264819
product: 264807
reactant: 264795
reactant: 264783
is version of: GO:0006461
fast: false
reversible: true
name: v92

264807
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000084

264795
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000080

264783
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000058

metaid_0000153
type: Parameter
constant: true
units: metaid_0000326
value: 5.84737E-6

metaid_0000124
type: Parameter
constant: true
units: metaid_0000324
value: 0.1146248

metaid_0000198
type: Parameter
constant: true
units: metaid_0000324
value: 9.954943

metaid_0000169
type: Parameter
constant: true
units: metaid_0000324
value: 931.1092

metaid_0000151
type: Parameter
constant: true
units: metaid_0000324
value: 11.1361

metaid_0000180
type: Parameter
constant: true
units: metaid_0000325
value: 615.0325

metaid_0000249
type: Reaction
kinetic law: 262212
product: 262200
product: 262188
reactant: 262176
is version of: GO:0043241
fast: false
reversible: true
name: v37

262200
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000045

262188
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

262176
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000038

metaid_0000167
type: Parameter
constant: true
units: metaid_0000326
value: 9.826084E-6

metaid_0000138
type: Parameter
constant: true
units: metaid_0000324
value: 171.6947

blabla 1
type: Species
constant: false
boundary condition: true
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: t_Raf*

metaid_0000353
type: Parameter
constant: true
units: metaid_0000321
value: 50000.0
name: total_Receptors

metaid_0000282
type: Reaction
kinetic law: 263760
product: 263748
reactant: 263736
is version of: MOD:00000
fast: false
reversible: true
name: v70

263748
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000069

263736
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000068

metaid_0000319
type: Reaction
kinetic law: 265491
product: 265479
product: 265467
reactant: 265455
is version of: GO:0043241
fast: false
reversible: true
name: v107

265479
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000024

265467
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

265455
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000093

metaid_0000254
type: Reaction
kinetic law: 262456
product: 262444
reactant: 262431
reactant: 262418
is version of: GO:0006461
fast: false
reversible: true
name: v42

262444
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000051

262431
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

262418
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000049

metaid_0000298
type: Reaction
kinetic law: 264529
product: 264517
reactant: 264505
reactant: 264493
is version of: GO:0006461
fast: false
reversible: true
name: v86

264517
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000079

264505
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000077

264493
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000052

metaid_0000145
type: Parameter
constant: true
units: metaid_0000324
value: 196.6479

metaid_0000280
type: Reaction
kinetic law: 263675
product: 263663
product: 263651
reactant: 263639
is version of: GO:0043241
fast: false
reversible: true
name: v68

263663
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

263651
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000024

263639
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000026

metaid_0000296
type: Reaction
kinetic law: 264433
product: 264421
reactant: 264409
reactant: 264397
is version of: GO:0006461
fast: false
reversible: true
name: v84

264421
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000078

264409
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000077

264397
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000049

metaid_0000201
type: Parameter
constant: true
units: metaid_0000326
value: 0.003826571

metaid_0000268
type: Reaction
kinetic law: 263131
product: 263119
reactant: 263107
reactant: 263095
is version of: GO:0006461
fast: false
reversible: true
name: v56

263119
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000066

263107
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000065

263095
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000064

metaid_0000225
type: Reaction
kinetic law: 261086
product: 261074
is version of: GO:0032800
fast: false
reversible: false
name: v13

261074
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000007

metaid_0000143
type: Parameter
constant: true
units: metaid_0000325
value: 0.4545611

metaid_0000159
type: Parameter
constant: true
units: metaid_0000326
value: 1.445554E-4

metaid_0000335
type: Reaction
kinetic law: 265910
product: 265897
product: 265884
reactant: 265871
is version of: GO:0043241
fast: false
reversible: true
name: v116

265897
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000070

265884
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

265871
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000096

metaid_0000239
type: Reaction
kinetic law: 261741
product: 261728
product: 261716
reactant: 261704
is version of: GO:0043241
fast: false
reversible: true
name: v27

261728
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000033

261716
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000040

261704
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000041

metaid_0000209
type: Parameter
constant: true
units: metaid_0000326
value: 1.714511E-4

metaid_0000342
type: Reaction
kinetic law: 266236
product: 266223
reactant: 266210
is version of: MOD:00000
fast: false
reversible: true
name: v123

266223
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000073

266210
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

metaid_0000262
type: Reaction
kinetic law: 262842
product: 262830
reactant: 262818
reactant: 262806
is version of: GO:0006461
fast: false
reversible: true
name: v50

262830
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000059

262818
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000054

262806
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000058

metaid_0000230
type: Reaction
kinetic law: 261315
product: 261303
reactant: 261291
reactant: 261279
is version of: GO:0006461
fast: false
reversible: true
name: v18

261303
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000032

261291
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030

261279
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

metaid_0000274
type: Reaction
kinetic law: 263385
product: 263373
reactant: 263361
is version of: GO:0030163
fast: false
reversible: false
name: v62

263373
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000092

263361
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000013

metaid_0000246
type: Reaction
kinetic law: 262080
product: 262068
product: 262056
reactant: 262044
is version of: GO:0043241
fast: false
reversible: true
name: v34

262068
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000035

262056
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

262044
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030

metaid_0000340
type: Reaction
kinetic law: 266144
product: 266131
reactant: 266118
reactant: 266105
is version of: GO:0006461
fast: false
reversible: true
name: v121

266131
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000098

266118
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

266105
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000041

metaid_0000260
type: Reaction
kinetic law: 262746
product: 262733
reactant: 262721
reactant: 262709
is version of: GO:0006461
fast: false
reversible: true
name: v48

262733
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000057

262721
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000058

262709
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000056

metaid_0000272
type: Reaction
kinetic law: 263313
product: 263301
reactant: 263289
is version of: GO:0030163
fast: false
reversible: false
name: v60

263301
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000091

263289
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000011

metaid_0000309
type: Reaction
kinetic law: 265059
product: 265047
product: 265035
reactant: 265023
is version of: GO:0043241
fast: false
reversible: true
name: v97

265047
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000082

265035
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000088

265023
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000087

metaid_0000244
type: Reaction
kinetic law: 261984
product: 261972
product: 261960
reactant: 261947
is version of: GO:0043241
fast: false
reversible: true
name: v32

261972
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000043

261960
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

261947
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000040

metaid_0000288
type: Reaction
kinetic law: 264049
product: 264037
product: 264025
reactant: 264013
is version of: GO:0043241
fast: false
reversible: true
name: v76

264037
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000077

264025
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000076

264013
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000075

ORG:
  orgname: EMBL-EBI
n:
  given: Vijayalakshmi
  family: Chelliah