BIOMD0000000366
type: SBMLModel
time units: 709214
species: 8
reaction: 16
substance units: 709238
is: GO:0007596
occurs in: http://identifiers.org/taxonomy/2759
reaction: 20
reaction: 13
species: 1
modified:
  W3 CDTF: Fri Apr 20 21:02:28 BST 2012
parameter: 22
parameter: 32
species: 12
compartment: 35
reaction: 19
species: 11
parameter: 25
parameter: 31
parameter: 29
species: 7
area units: 498119
length unit: length
reaction: 14
reaction: 17
species: 6
species: 4
units def: 709238
parameter: 23
parameter: 33
species: 10
units def: 709214
parameter: 26
name: Orfao2008_ThrombinGeneration_AmidolyticActivity
creator:
  ORG:
    orgname: EBI
  n:
    given: Michael
    family: Schubert
is: MODEL1108260000
is described by: j.jmaa.2008.05.060
rule: 37
name: Henri-Michaelis-Menten (irreversible) kcat
volume units: 498095
reaction: 15
species: 5
species: 3
parameter: 28
parameter: 34
function def: 36
curated: true
species: 2
reaction: 18
parameter: 21
parameter: 27
created:
  W3 CDTF: Fri Aug 26 17:38:20 BST 2011
species: 9
parameter: 24
parameter: 30

709214
type: SBMLUnitsDef
unit: 709226
name: time

709226
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 60.0
kind: SECOND

8
type: Species
is: P12259
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.02999999
initial amount: NaN
in compartment: 35
name: V

35
type: Compartment
constant: true
size: 1.0
spatial dimensions: 3.0
name: compartment_1

16
type: Reaction
kinetic law: 709445
modifier: 709433
product: 709420
reactant: 709408
fast: false
reversible: false
name: R4

7
type: Species
is: P00734
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 35
name: IIa

709420
type: SpeciesReference
is: SBO:0000011
stoichiometry: 1.0
species: 6

6
type: Species
is: P12259
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 35
name: Va

709408
type: SpeciesReference
is: SBO:0000010
stoichiometry: 1.0
species: 8

709238
type: SBMLUnitsDef
unit: 709250
name: substance

709250
type: SBMLUnit
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE

20
type: Reaction
kinetic law: 709613
product: 709601
reactant: 709589
fast: false
reversible: false
name: R8

709601
type: SpeciesReference
is: SBO:0000011
stoichiometry: 1.0
species: 11

11
type: Species
name: IIa_ATIII
constant: false
initial concentration: 0.0
has only substance units: false
has part: P00734
in compartment: 35
boundary condition: false
has part: P01008
initial amount: NaN

709589
type: SpeciesReference
is: SBO:0000010
stoichiometry: 1.0
species: 7

13
type: Reaction
kinetic law: 709299
modifier: 709286
product: 709274
reactant: 709262
fast: false
reversible: false
name: R1

12
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.03
initial amount: NaN
in compartment: 35
name: RVV

709274
type: SpeciesReference
is: SBO:0000011
stoichiometry: 1.0
species: 2

2
type: Species
is: P00742
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 35
name: Xa

709262
type: SpeciesReference
is: SBO:0000010
stoichiometry: 1.0
species: 1

1
type: Species
is: P00742
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.1999999
initial amount: NaN
in compartment: 35
name: X

22
type: Parameter
is: SBO:0000371
constant: true
value: 23.65
name: km_X

32
type: Parameter
is: SBO:0000035
constant: true
value: 0.1762
name: ki_IIaAlpha2M

19
type: Reaction
kinetic law: 709577
product: 709565
reactant: 709553
fast: false
reversible: false
name: R7

709565
type: SpeciesReference
is: SBO:0000011
stoichiometry: 1.0
species: 10

10
type: Species
initial amount: NaN
boundary condition: false
constant: false
has only substance units: false
name: IIa_alpha2M
has part: P01023
initial concentration: 0.0
has part: P00734
in compartment: 35

709553
type: SpeciesReference
is: SBO:0000010
stoichiometry: 1.0
species: 7

25
type: Parameter
is: SBO:0000038
constant: true
value: 801.4
name: k_PL

31
type: Parameter
is: SBO:0000371
constant: true
value: 0.06148
name: km_2

29
type: Parameter
is: SBO:0000371
constant: true
value: 62.25
name: km_II

14
type: Reaction
kinetic law: 709335
product: 709323
reactant: 709311
fast: false
reversible: false
name: R2

709323
type: SpeciesReference
is: SBO:0000011
stoichiometry: 1.0
species: 3

3
type: Species
name: Xa_ATIII
initial amount: NaN
has part: P00742
boundary condition: false
has part: P01008
constant: false
initial concentration: 0.0
has only substance units: false
in compartment: 35

709311
type: SpeciesReference
is: SBO:0000010
stoichiometry: 1.0
species: 2

17
type: Reaction
kinetic law: 709493
modifier: 709481
product: 709469
reactant: 709457
fast: false
reversible: false
name: R5

5
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 35
name: PT

709469
type: SpeciesReference
is: SBO:0000011
stoichiometry: 1.0
species: 7

709457
type: SpeciesReference
is: SBO:0000010
stoichiometry: 1.0
species: 9

9
type: Species
is: P00734
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.4
initial amount: NaN
in compartment: 35
name: II

4
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.04999999
initial amount: NaN
in compartment: 35
name: PL

23
type: Parameter
is: SBO:0000035
constant: true
value: 4.531
name: ki_Xa

33
type: Parameter
is: SBO:0000035
constant: true
value: 0.7859
name: ki_IIaATIII

26
type: Parameter
is: SBO:0000025
constant: true
value: 7.844
name: kcat_V

15
type: Reaction
kinetic law: 709396
product: 709383
reactant: 709371
reactant: 709359
reactant: 709347
fast: false
reversible: true
name: R3

709383
type: SpeciesReference
is: SBO:0000011
stoichiometry: 1.0
species: 5

709371
type: SpeciesReference
is: SBO:0000010
stoichiometry: 1.0
species: 4

709359
type: SpeciesReference
is: SBO:0000010
stoichiometry: 1.0
species: 2

709347
type: SpeciesReference
is: SBO:0000010
stoichiometry: 1.0
species: 6

28
type: Parameter
is: SBO:0000025
constant: true
value: 43.87
name: kcat_II

34
type: Parameter
constant: false
value: 0.0
name: AmAct

18
type: Reaction
kinetic law: 709541
modifier: 709529
product: 709517
reactant: 709505
fast: false
reversible: false
name: R6

709517
type: SpeciesReference
is: SBO:0000011
stoichiometry: 1.0
species: 7

709505
type: SpeciesReference
is: SBO:0000010
stoichiometry: 1.0
species: 9

21
type: Parameter
is: SBO:0000025
constant: true
value: 239.1
name: kcat_X

27
type: Parameter
is: SBO:0000371
constant: true
value: 149.7
name: km_V

24
type: Parameter
is: SBO:0000037
constant: true
value: 122.9
name: k_PT

30
type: Parameter
is: SBO:0000025
constant: true
value: 12.4
name: kcat_2