BIOMD0000000268
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280700
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280441
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704080
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280396
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280366
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280708
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280716
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703633
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703645
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280501
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706196
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280405
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280367
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280704
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280603
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280489
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705749
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280417
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705737
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280419
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280497
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706014
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280415
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706026
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280412
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280369
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280407
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280697
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280477
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705254
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280389
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705230
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280467
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704880
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280368
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704868
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280485
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705567
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705555
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280388
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280469
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704952
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704940
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280737
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280455
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704432
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280449
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704286
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280473
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705108
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705084
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280463
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704746
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280457
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704528
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280696
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280401
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280725
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703754
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280733
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280437
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704007
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280588
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280451
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704323
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704310
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280445
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704177
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280721
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280729
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280576
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703935
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280605
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280584
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280499
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280784
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280595
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280479
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280601
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280580
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280487
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280739
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value: 4530.0

280675
type: Parameter
constant: true
units: 703549
value: 0.5

280439
type: Reaction
kinetic law: 704043
reactant: 704031
is version of: GO:0006751
fast: false
reversible: true

704031
type: SpeciesReference
stoichiometry: 1.0
species: 280400

280683
type: Parameter
constant: true
units: 703585
value: 3900.0

280447
type: Reaction
kinetic law: 704226
product: 704213
reactant: 704201
is version of: GO:0034635
fast: false
reversible: true

704213
type: SpeciesReference
stoichiometry: 1.0
species: 280400

704201
type: SpeciesReference
stoichiometry: 1.0
species: 280409

280715
type: Parameter
constant: true
units: 703549
value: 41.0

280655
type: Parameter
constant: true
units: 703549
value: 5700.0

280456
type: Reaction
kinetic law: 704480
product: 704468
reactant: 704456
is version of: R00941
fast: false
reversible: true

704468
type: SpeciesReference
stoichiometry: 1.0
species: 280384

704456
type: SpeciesReference
stoichiometry: 1.0
species: 280395

280481
type: Reaction
kinetic law: 705423
product: 705411
reactant: 705399
reactant: 705387
is version of: R02101
fast: false
reversible: true

705411
type: SpeciesReference
stoichiometry: 1.0
species: 280391

705399
type: SpeciesReference
stoichiometry: 1.0
species: 280387

705387
type: SpeciesReference
stoichiometry: 1.0
species: 280376

280376
type: Species
constant: false
is version of: C00365
has only substance units: false
is version of: CHEBI:17622
in compartment: 280367
initial concentration: 20.0
boundary condition: true
initial amount: NaN
name: dUMP

280723
type: Parameter
constant: true
units: 703585
value: 260.0

280663
type: Parameter
constant: true
units: 703549
value: 5700.0

280464
type: Reaction
kinetic law: 704818
product: 704806
product: 704794
reactant: 704782
reactant: 704770
fast: false
reversible: true

704806
type: SpeciesReference
stoichiometry: 1.0
species: 280425

704794
type: SpeciesReference
stoichiometry: 1.0
species: 280392

704782
type: SpeciesReference
stoichiometry: 1.0
species: 280427

280427
type: Species
has only substance units: false
initial amount: NaN
in compartment: 280369
is version of: CHEBI:17724
constant: false
is version of: C01026
name: Dimethylglycine
boundary condition: false
initial concentration: 0.707382712261505

704770
type: SpeciesReference
stoichiometry: 1.0
species: 280384

280731
type: Parameter
constant: true
units: 703549
value: 1.4

280671
type: Parameter
constant: true
units: 703549
value: 0.01

280435
type: Reaction
kinetic law: 703971
reactant: 703959
is version of: GO:0006538
fast: false
reversible: true

703959
type: SpeciesReference
stoichiometry: 1.0
species: 280397

280703
type: Parameter
constant: true
units: 703585
value: 500000.0

280444
type: Reaction
kinetic law: 704153
product: 704141
reactant: 704129
is version of: GO:0034635
fast: false
reversible: true

704141
type: SpeciesReference
stoichiometry: 1.0
species: 280401

704129
type: SpeciesReference
stoichiometry: 1.0
species: 280411

ORG:
  orgname: EMBL-EBI
n:
  given: Lukas
  family: Endler

280711
type: Parameter
constant: true
units: 703549
value: 100.0

280589
type: Parameter
constant: true
units: 703585
value: 4025.0

280651
type: Parameter
constant: true
units: 703585
value: 20000.0

280768
type: Parameter
constant: true
units: 703549
value: 10.4

280452
type: Reaction
kinetic law: 704371
product: 704359
reactant: 704347
is version of: GO:0015816
fast: false
reversible: true

704359
type: SpeciesReference
stoichiometry: 1.0
species: 280408

704347
type: SpeciesReference
stoichiometry: 1.0
species: 280396

280719
type: Parameter
constant: true
units: 703549
value: 300.0

280597
type: Parameter
constant: true
units: 703633
value: 1.0

280776
type: Parameter
constant: false
value: NaN
name: Aminoacid_input

280748
type: Parameter
constant: true
units: 703549
value: 100.0

280508
type: Reaction
kinetic law: 706401
reactant: 706389
is version of: GO:0006751
fast: false
reversible: true

706389
type: SpeciesReference
stoichiometry: 1.0
species: 280411

280432
type: Reaction
kinetic law: 703923
reactant: 703910
is version of: GO:0019456
fast: false
reversible: true

703910
type: SpeciesReference
stoichiometry: 1.0
species: 280399

280577
type: Parameter
constant: false
units: 703585
value: NaN

280440
type: Reaction
kinetic law: 704068
product: 704055
is version of: GO:0042883
fast: false
reversible: true

704055
type: SpeciesReference
stoichiometry: 1.0
species: 280399

280756
type: Parameter
constant: true
units: 703706
value: 5600.0

703706
type: SBMLUnitsDef
unit: 703730
unit: 703718
name: 1/uM

703730
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE

703718
type: SBMLUnit
exponent: -1.0
scale: -6
multipler: 1.0
kind: MOLE

280385
type: Species
name: c_5-methyl-THF
in compartment: 280367
boundary condition: false
is version of: CHEBI:15641
constant: false
is version of: C00440
has only substance units: false
initial concentration: 4.4965335653401
initial amount: NaN

280707
type: Parameter
constant: true
units: 703549
value: 100.0

280585
type: Parameter
constant: true
units: 703549
value: 3000.0

280764
type: Parameter
constant: true
units: 703549
value: 0.09

280593
type: Parameter
constant: true
units: 703549
value: 2100.0

280689
type: Parameter
constant: true
units: 703658
value: 0.03

703658
type: SBMLUnitsDef
unit: 703694
unit: 703682
unit: 703670
name: 1/(uM*h)

703694
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 3600.0
kind: SECOND

703682
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE

703670
type: SBMLUnit
exponent: -1.0
scale: -6
multipler: 1.0
kind: MOLE

280772
type: Parameter
constant: true
units: dimensionless
value: 1.75

703524
type: SBMLUnitsDef
unit: 703536
name: micromole

703536
type: SBMLUnit
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE

280744
type: Parameter
constant: true
units: 703549
value: 500.0

280573
type: Parameter
constant: false
units: 703549
value: NaN

280669
type: Parameter
constant: true
units: 703549
value: 1.0

280752
type: Parameter
constant: true
units: 703706
value: 300.0

280504
type: Reaction
kinetic law: 706280
product: 706268
reactant: 706256
reactant: 706244
is version of: R00497
fast: false
reversible: true

706268
type: SpeciesReference
stoichiometry: 1.0
species: 280411

706256
type: SpeciesReference
stoichiometry: 1.0
species: 280408

706244
type: SpeciesReference
stoichiometry: 1.0
species: 280407

280495
type: Reaction
kinetic law: 705966
product: 705954
reactant: 705942
is version of: R00192
fast: false
reversible: true

705954
type: SpeciesReference
stoichiometry: 1.0
species: 280413

705942
type: SpeciesReference
stoichiometry: 1.0
species: 280416

280581
type: Parameter
constant: true
units: 703549
value: 150.0

280677
type: Parameter
constant: true
units: 703585
value: 500.0

280760
type: Parameter
constant: true
units: 703706
value: 30.0

280488
type: Reaction
reactant: 705640
product: 705677
modifier: 705701
is version of: R02821
fast: false
modifier: 705713
modifier: 705689
reactant: 705652
product: 705664
reversible: true
kinetic law: 705725

705640
type: SpeciesReference
stoichiometry: 1.0
species: 280413

705677
type: SpeciesReference
stoichiometry: 1.0
species: 280427

705652
type: SpeciesReference
stoichiometry: 1.0
species: 280375

280375
type: Species
initial concentration: 50.0
is: CHEBI:17750
initial amount: NaN
boundary condition: true
constant: false
is: C00719
name: Betaine
in compartment: 280367
has only substance units: false

705664
type: SpeciesReference
stoichiometry: 1.0
species: 280419

280685
type: Parameter
constant: true
units: 703549
value: 43.0

280507
type: Reaction
kinetic law: 706377
product: 706365
reactant: 706353
reactant: 706341
is version of: R00115
fast: false
reversible: true

706365
type: SpeciesReference
stoichiometry: 2.0
species: 280411

706353
type: SpeciesReference
stoichiometry: 1.0
species: 280373

706341
type: SpeciesReference
stoichiometry: 1.0
species: 280409

280781
type: Parameter
constant: true
units: 703585
value: 273.0

280657
type: Parameter
constant: true
units: 703549
value: 5700.0

280688
type: Parameter
constant: true
units: 703585
value: 1.5E7

280639
type: Parameter
constant: true
units: 703585
value: 15000.0

280740
type: Parameter
constant: true
units: 703549
value: 2000.0

280483
type: Reaction
is version of: R01220
reactant: 705435
reactant: 705447
modifier: 705471
reversible: true
modifier: 705483
product: 705459
fast: false
kinetic law: 705495

705435
type: SpeciesReference
stoichiometry: 1.0
species: 280387

705447
type: SpeciesReference
stoichiometry: 1.0
species: 280373

705459
type: SpeciesReference
stoichiometry: 1.0
species: 280385

280647
type: Parameter
constant: true
units: 703549
value: 10.0

280665
type: Parameter
constant: true
units: 703549
value: 5700.0

280476
type: Reaction
kinetic law: 705218
product: 705205
product: 705193
reactant: 705181
reactant: 705169
fast: false
reversible: true

705205
type: SpeciesReference
stoichiometry: 1.0
species: 280383

705193
type: SpeciesReference
stoichiometry: 1.0
species: 280403

705181
type: SpeciesReference
stoichiometry: 1.0
species: 280372

280372
type: Species
is version of: C003838
is version of: CHEBI:18349
constant: false
boundary condition: true
has only substance units: false
initial concentration: 10.0
initial amount: NaN
in compartment: 280367

705169
type: SpeciesReference
stoichiometry: 1.0
species: 280389

280491
type: Reaction
kinetic law: 705821
modifier: 705809
product: 705797
reactant: 705785
is version of: R00650
fast: false
reversible: true

705797
type: SpeciesReference
stoichiometry: 1.0
species: 280417

705785
type: SpeciesReference
stoichiometry: 1.0
species: 280419

280673
type: Parameter
constant: true
units: 703585
value: 2000.0

280681
type: Parameter
constant: true
units: 703549
value: 520.0

280668
type: Parameter
constant: true
units: 703549
value: 25.0

280503
type: Reaction
kinetic law: 706232
reactant: 706220
is version of: GO:0006538
fast: false
reversible: true

706220
type: SpeciesReference
stoichiometry: 1.0
species: 280404

280676
type: Parameter
constant: true
units: 703549
value: 4.0

280627
type: Parameter
constant: true
units: 703549
value: 22.0

280471
type: Reaction
kinetic law: 705000
product: 704988
reactant: 704976
fast: false
reversible: true

704988
type: SpeciesReference
stoichiometry: 1.0
species: 280408

704976
type: SpeciesReference
stoichiometry: 3.0
species: 280423

280684
type: Parameter
constant: true
units: 703549
value: 3.0

280635
type: Parameter
constant: true
units: 703585
value: 15000.0

280653
type: Parameter
constant: true
units: 703585
value: 10000.0

280448
type: Reaction
kinetic law: 704262
product: 704250
reactant: 704238
is version of: GO:0034635
fast: false
reversible: true

704250
type: SpeciesReference
stoichiometry: 1.0
species: 280400

704238
type: SpeciesReference
stoichiometry: 1.0
species: 280409

280661
type: Parameter
constant: true
units: 703585
value: 10000.0

280643
type: Parameter
constant: true
units: 703585
value: 180000.0

280656
type: Parameter
constant: true
units: 703585
value: 10000.0

280664
type: Parameter
constant: true
units: 703585
value: 10000.0

280615
type: Parameter
constant: true
units: 703549
value: 50.0

280672
type: Parameter
constant: true
units: 703549
value: 0.01

280623
type: Parameter
constant: true
units: 703549
value: 3.0

280436
type: Reaction
kinetic law: 703995
reactant: 703983
is version of: GO:0006546
fast: false
reversible: true

703983
type: SpeciesReference
stoichiometry: 1.0
species: 280396

280680
type: Parameter
constant: true
units: 703549
value: 4.9

280631
type: Parameter
constant: true
units: 703585
value: 15000.0

280380
type: Species
initial amount: NaN
constant: false
has only substance units: false
initial concentration: 0.0
name: CO2
is version of: C00011
is version of: CHEBI:16526
boundary condition: true
in compartment: 280368

280460
type: Reaction
kinetic law: 704637
product: 704625
reactant: 704613
reactant: 704601
is version of: R09093
fast: false
reversible: true

704625
type: SpeciesReference
stoichiometry: 1.0
species: 280392

704613
type: SpeciesReference
stoichiometry: 1.0
species: 280381

280381
type: Species
has only substance units: false
initial amount: NaN
name: Formaldehyde
constant: false
is version of: CHEBI:16842
in compartment: 280369
boundary condition: true
initial concentration: 500.0
is version of: C00067

704601
type: SpeciesReference
stoichiometry: 1.0
species: 280384

280769
type: Parameter
constant: true
units: dimensionless
value: 3.25

280652
type: Parameter
constant: true
units: 703549
value: 100.0

280777
type: Parameter
constant: true
units: 703549
value: 30.0

280660
type: Parameter
constant: true
units: 703633
value: 100.0

280611
type: Parameter
constant: true
units: 703585
value: 1050.0

280619
type: Parameter
constant: true
units: 703549
value: 10000.0

280749
type: Parameter
constant: true
units: 703549
value: 1900.0

280757
type: Parameter
constant: true
units: 703549
value: 300.0

280509
type: Reaction
kinetic law: 706425
reactant: 706413
is version of: GO:0006751
fast: false
reversible: true

706413
type: SpeciesReference
stoichiometry: 1.0
species: 280409

280783
type: Parameter
constant: true
units: 703585
value: 70.0

280765
type: Parameter
constant: true
units: 703585
value: 892.5

280607
type: Parameter
constant: true
units: 703585
value: 913.4

280773
type: Parameter
constant: true
units: dimensionless
value: 0.25

280649
type: Parameter
constant: true
units: 703549
value: 250.0

280745
type: Parameter
constant: true
units: 703585
value: 3600.0

280505
type: Reaction
kinetic law: 706329
product: 706316
reactant: 706304
reactant: 706292
is version of: R00274
fast: false
reversible: true

706316
type: SpeciesReference
stoichiometry: 1.0
species: 280409

706304
type: SpeciesReference
stoichiometry: 1.0
species: 280379

706292
type: SpeciesReference
stoichiometry: 2.0
species: 280411

280496
type: Reaction
kinetic law: 705990
reactant: 705978
is version of: R0006565
fast: false
reversible: true

705978
type: SpeciesReference
stoichiometry: 1.0
species: 280415

280753
type: Parameter
constant: true
units: 703549
value: 0.01

280629
type: Parameter
constant: true
units: 703633
value: 20.0

280761
type: Parameter
constant: true
units: 703585
value: 4500.0

280637
type: Parameter
constant: true
units: 703549
value: 320.0

280645
type: Parameter
constant: true
units: 703585
value: 594000.0

280500
type: Reaction
reactant: 706124
kinetic law: 706184
reactant: 706136
modifier: 706160
reversible: true
product: 706148
fast: false
modifier: 706172
is version of: R00894

706124
type: SpeciesReference
stoichiometry: 1.0
species: 280405

706136
type: SpeciesReference
stoichiometry: 1.0
species: 280404

706148
type: SpeciesReference
stoichiometry: 1.0
species: 280407

280741
type: Parameter
constant: true
units: 703549
value: 0.035

280484
type: Reaction
kinetic law: 705543
product: 705531
product: 705519
reactant: 705507
is version of: R01220
fast: false
reversible: true

705531
type: SpeciesReference
stoichiometry: 1.0
species: 280373

705519
type: SpeciesReference
stoichiometry: 1.0
species: 280388

705507
type: SpeciesReference
stoichiometry: 1.0
species: 280387

280648
type: Parameter
constant: true
units: 703585
value: 790000.0

280617
type: Parameter
constant: true
units: 703585
value: 3.0E7

280492
type: Reaction
reactant: 705833
reactant: 705845
kinetic law: 705894
is version of: R00367
product: 705870
product: 705857
reversible: true
modifier: 705882
fast: false

705833
type: SpeciesReference
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species: 280417

705845
type: SpeciesReference
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species: 280408

705870
type: SpeciesReference
stoichiometry: 1.0
species: 280425

705857
type: SpeciesReference
stoichiometry: 1.0
species: 280416

280625
type: Parameter
constant: true
units: 703585
value: 6300.0

280633
type: Parameter
constant: true
units: 703549
value: 3400.0

280641
type: Parameter
constant: true
units: 703549
value: 50.0

280628
type: Parameter
constant: true
units: 703658
value: 0.03

280472
type: Reaction
fast: false
reactant: 705012
reversible: true
kinetic law: 705072
product: 705048
modifier: 705060
reactant: 705024
product: 705036

705012
type: SpeciesReference
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species: 280385

705048
type: SpeciesReference
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species: 280419

705024
type: SpeciesReference
stoichiometry: 1.0
species: 280413

705036
type: SpeciesReference
stoichiometry: 1.0
species: 280383

280636
type: Parameter
constant: true
units: 703549
value: 50.0

280480
type: Reaction
kinetic law: 705375
product: 705363
reactant: 705351
reactant: 705339
fast: false
reversible: true

705363
type: SpeciesReference
stoichiometry: 1.0
species: 280387

705351
type: SpeciesReference
stoichiometry: 1.0
species: 280381

705339
type: SpeciesReference
stoichiometry: 1.0
species: 280383

280779
type: Parameter
constant: true
units: 703549
value: 150.0

280644
type: Parameter
constant: true
units: 703549
value: 2.0

280613
type: Parameter
constant: true
units: 703585
value: 11440.0

280621
type: Parameter
constant: true
units: 703585
value: 2000.0

280616
type: Parameter
constant: true
units: 703549
value: 600.0

280624
type: Parameter
constant: true
units: 703549
value: 43.0

280759
type: Parameter
constant: true
units: 703549
value: 22.0

280699
type: Parameter
constant: true
units: 703549
value: 16.0

280632
type: Parameter
constant: true
units: 703549
value: 50.0

280767
type: Parameter
constant: true
units: 703549
value: 107.0

280775
type: Parameter
constant: false
units: 703742
value: NaN

280609
type: Parameter
constant: true
units: 703633
value: 1.0

280640
type: Parameter
constant: true
units: 703549
value: 50.0

280736
type: Parameter
constant: true
units: 703549
value: 150.0

280612
type: Parameter
constant: true
units: 703549
value: 20.0

280747
type: Parameter
constant: true
units: 703706
value: 5597.0

280620
type: Parameter
constant: true
units: 703549
value: 3200.0

280755
type: Parameter
constant: true
units: 703585
value: 5400.0

280695
type: Parameter
constant: true
units: 703549
value: 14.0

280377
type: Species
has only substance units: false
is version of: CHEBI:27470
name: Folate
is version of: C00504
boundary condition: true
initial concentration: 20.1
initial amount: NaN
constant: false
in compartment: 280369

280763
type: Parameter
constant: true
units: 703549
value: 1330.0

280724
type: Parameter
constant: true
units: 703549
value: 63.0

280465
type: Reaction
kinetic law: 704855
product: 704842
reactant: 704830
fast: false
reversible: true

704842
type: SpeciesReference
stoichiometry: 1.0
species: 280393

704830
type: SpeciesReference
stoichiometry: 1.0
species: 280392

280771
type: Parameter
constant: true
units: dimensionless
value: 1.75

280732
type: Parameter
constant: true
units: 703585
value: 320.0

280429
type: Reaction
reactant: 703790
product: 703814
product: 703802
kinetic law: 703838
fast: false
is version of: GO:0006751
reversible: true
product: 703826

703790
type: SpeciesReference
stoichiometry: 1.0
species: 280401

703814
type: SpeciesReference
stoichiometry: 1.0
species: 280396

703802
type: SpeciesReference
stoichiometry: 1.0
species: 280399

703826
type: SpeciesReference
stoichiometry: 1.0
species: 280397

280608
type: Parameter
constant: true
units: 703549
value: 150.0

280743
type: Parameter
constant: true
units: 703585
value: 1500.0

280751
type: Parameter
constant: true
units: 703549
value: 8200.0

280712
type: Parameter
constant: true
units: 703549
value: 0.01

280691
type: Parameter
constant: true
units: 703633
value: 22.0

280453
type: Reaction
kinetic law: 704408
product: 704395
reactant: 704383
is version of: GO:0032329
fast: false
reversible: true

704395
type: SpeciesReference
stoichiometry: 1.0
species: 280415

704383
type: SpeciesReference
stoichiometry: 1.0
species: 280371

280371
type: Species
has only substance units: false
is version of: C00716
initial amount: NaN
boundary condition: true
constant: false
is version of: CHEBI:17822
name: b_Ser
initial concentration: NaN
in compartment: 280366

280720
type: Parameter
constant: true
units: 703549
value: 360.0

280461
type: Reaction
kinetic law: 704697
product: 704685
product: 704673
reactant: 704661
reactant: 704649
fast: false
reversible: true

704685
type: SpeciesReference
stoichiometry: 1.0
species: 280380

704673
type: SpeciesReference
stoichiometry: 1.0
species: 280392

704661
type: SpeciesReference
stoichiometry: 1.0
species: 280423

704649
type: SpeciesReference
stoichiometry: 1.0
species: 280384

280728
type: Parameter
constant: true
units: 703585
value: 180.0

W3 CDTF: Fri Sep 24 16:00:03 BST 2010

W3 CDTF: Tue Sep 07 17:28:04 BST 2010