BIOMD0000000246
type: SBMLModel
parameter: metaid_0000129
rule: metaid_0000218
parameter: metaid_0000036
parameter: metaid_0000136
species: metaid_0000172
parameter: metaid_0000043
area units: metaid_0000005
parameter: metaid_0000059
rule: metaid_0000214
species: metaid_0000189
parameter: metaid_0000041
parameter: metaid_0000070
parameter: metaid_0000057
reaction: metaid_0000233
parameter: metaid_0000011
species: metaid_0000182
parameter: metaid_0000143
units def: metaid_0000280
rule: metaid_0000212
reaction: metaid_0000249
parameter: metaid_0000141
reaction: metaid_0000247
parameter: metaid_0000025
parameter: metaid_0000157
is: MODEL1004080000
species: metaid_0000193
species: metaid_0000175
reaction: metaid_0000272
parameter: metaid_0000112
parameter: metaid_0000098
parameter: metaid_0000128
parameter: metaid_0000035
parameter: metaid_0000091
parameter: metaid_0000096
parameter: metaid_0000126
parameter: metaid_0000033
units def: metaid_0000291
parameter: metaid_0000165
parameter: metaid_0000049
species: metaid_0000176
units def: metaid_0000279
length unit: length
parameter: metaid_0000133
reaction: metaid_0000239
rule: metaid_0000228
parameter: metaid_0000140
reaction: metaid_0000264
parameter: metaid_0000074
parameter: metaid_0000156
units def: metaid_0000285
species: metaid_0000186
substance units: metaid_0000274
reaction: metaid_0000262
parameter: metaid_0000107
parameter: metaid_0000154
parameter: metaid_0000088
units def: metaid_0000278
parameter: metaid_0000118
rule: metaid_0000224
parameter: metaid_0000105
parameter: metaid_0000090
rule: metaid_0000230
species: metaid_0000179
parameter: metaid_0000095
parameter: metaid_0000164
rule: metaid_0000219
curated: true
parameter: metaid_0000162
rule: metaid_0000204
reaction: metaid_0000240
parameter: metaid_0000014
parameter: metaid_0000132
rule: metaid_0000210
rule: metaid_0000215
parameter: metaid_0000130
reaction: metaid_0000254
parameter: metaid_0000060
parameter: metaid_0000146
compartment: metaid_0000167

metaid_0000129
type: Parameter
constant: false
units: metaid_0000278
value: NaN

metaid_0000278
type: SBMLUnitsDef
unit: 865642
name: milliVolt

865642
type: SBMLUnit
exponent: 1.0
scale: -3
multipler: 1.0
kind: VOLT

metaid_0000036
type: Parameter
constant: true
units: dimensionless
value: 2.0

metaid_0000136
type: Parameter
constant: true
units: metaid_0000279
value: 36.0
name: g_Na

metaid_0000279
type: SBMLUnitsDef
unit: 865655
name: nanoSievert

865655
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: SIEVERT

metaid_0000172
type: Species
initial concentration: 5.0
is: C00076
initial amount: NaN
boundary condition: false
constant: false
in compartment: metaid_0000166
is: SBO:0000327
has only substance units: false
substance units: metaid_0000275
is: CHEBI:29108

metaid_0000166
type: Compartment
is part of: FMA:67883
is version of: GO:0005615
is: SBO:0000290
constant: true
size: 1.0
spatial dimensions: 3.0

metaid_0000275
type: SBMLUnitsDef
unit: 865603
name: micromole

865603
type: SBMLUnit
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE

metaid_0000043
type: Parameter
constant: true
units: metaid_0000282
value: 0.1
name: K_p

metaid_0000282
type: SBMLUnitsDef
unit: 865707
unit: 865694
name: nM

865707
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE

865694
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000059
type: Parameter
constant: true
units: metaid_0000290
value: 0.7
name: vd_PCC

metaid_0000290
type: SBMLUnitsDef
unit: 865921
unit: 865909
unit: 865896
name: nM_per_h

865921
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 3600.0
kind: SECOND

865909
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE

865896
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000189
type: Species
constant: false
initial concentration: 0.12
is version of: P16220
has only substance units: false
in compartment: metaid_0000167
boundary condition: false
name: CB
initial amount: NaN
is: SBO:0000252

metaid_0000167
type: Compartment
is: GO:0005737
is part of: FMA:54527
is: SBO:0000290
constant: true
size: 1.0
spatial dimensions: 3.0

metaid_0000041
type: Parameter
constant: true
units: metaid_0000288
value: 0.01
name: kd_n

metaid_0000288
type: SBMLUnitsDef
unit: 865847
name: per_h

865847
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 3600.0
kind: SECOND

metaid_0000070
type: Parameter
constant: true
value: 0.2

metaid_0000057
type: Parameter
constant: true
units: metaid_0000290
value: NaN
name: V1_PC

metaid_0000233
type: Reaction
kinetic law: 866071
modifier: 866059
product: 866047
is version of: GO:0070588
is: SBO:0000185
fast: false
reversible: true

metaid_0000184
type: Species
initial concentration: 2.41
is version of: O00327
boundary condition: false
name: B_C
constant: false
initial amount: NaN
in compartment: metaid_0000167
is: SBO:0000252
has only substance units: false

866047
type: SpeciesReference
stoichiometry: 0.001
species: metaid_0000170

metaid_0000170
type: Species
substance units: metaid_0000275
constant: false
is: CHEBI:29108
boundary condition: false
is: SBO:0000327
initial amount: NaN
initial concentration: 0.1
is: C00076
in compartment: metaid_0000167
has only substance units: false

metaid_0000011
type: Parameter
constant: true
units: dimensionless
value: 0.5
name: beta_IP3

metaid_0000182
type: Species
name: PC_CP
is: SBO:0000297
has part: Q16526
initial amount: NaN
has part: O15534
initial concentration: 0.2
is version of: C00562
has part: P56645
constant: false
boundary condition: false
has only substance units: false
in compartment: metaid_0000167

metaid_0000143
type: Parameter
constant: true
value: 105.0
name: V_ex1

metaid_0000280
type: SBMLUnitsDef
unit: 865668
name: microAmpere

865668
type: SBMLUnit
exponent: 1.0
scale: -6
multipler: 1.0
kind: AMPERE

metaid_0000249
type: Reaction
kinetic law: 866613
modifier: 866600
product: 866588
is version of: GO:0006412
is: SBO:0000184
fast: false
reversible: true

metaid_0000174
type: Species
is: SBO:0000278
has only substance units: false
name: M_C
initial concentration: 2.0
initial amount: NaN
in compartment: metaid_0000167
constant: false
boundary condition: false
encodes: Q16526
is version of: CHEBI:33699
encodes: Q49AN0

866588
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000177

metaid_0000177
type: Species
constant: false
boundary condition: false
initial amount: NaN
in compartment: metaid_0000167
name: C_C
has only substance units: false
has version: Q49AN0
is: SBO:0000252
has version: Q16526
initial concentration: 12.0

metaid_0000141
type: Parameter
constant: false
units: metaid_0000280
value: NaN
name: I_Na_abs

metaid_0000247
type: Reaction
kinetic law: 866528
product: 866516
reactant: 866504
is: SBO:0000216
fast: false
reversible: true

866516
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000178

metaid_0000178
type: Species
has version: O15055
boundary condition: false
constant: false
initial concentration: 0.13
initial amount: NaN
has version: P56645
name: P_CP
in compartment: metaid_0000167
has version: O15534
has only substance units: false
is: SBO:0000252

866504
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000176

metaid_0000176
type: Species
boundary condition: false
is: SBO:0000252
has version: O15055
constant: false
has version: P56645
initial amount: NaN
in compartment: metaid_0000167
has only substance units: false
name: P_C
initial concentration: 0.4
has version: O15534

metaid_0000025
type: Parameter
constant: true
units: metaid_0000282
value: 0.6
name: K_AP

metaid_0000157
type: Parameter
constant: true
value: 0.16
name: K_KCa

metaid_0000193
type: Species
constant: false
has only substance units: false
is: CHEBI:16865
boundary condition: true
is: SBO:0000327
is: C00334
in compartment: metaid_0000167
initial amount: NaN
initial concentration: NaN

metaid_0000175
type: Species
is version of: CHEBI:33699
initial concentration: 7.94
is: SBO:0000278
initial amount: NaN
boundary condition: false
name: M_B
constant: false
is version of: O00327
in compartment: metaid_0000167
has only substance units: false

metaid_0000272
type: Reaction
kinetic law: 867292
product: 867280
is version of: GO:0032800
is version of: GO:0004999
fast: false
reversible: true

867280
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000190

metaid_0000190
type: Species
in compartment: metaid_0000167
boundary condition: false
has only substance units: false
initial amount: NaN
is homolog to: P32241
name: VIP
constant: false
initial concentration: 0.0
is: SBO:0000244

metaid_0000112
type: Parameter
constant: false
units: metaid_0000278
value: NaN

metaid_0000098
type: Parameter
constant: true
units: kelvin
value: 273.15

metaid_0000128
type: Parameter
constant: true
value: 96485.0
name: Faraday

metaid_0000035
type: Parameter
constant: true
units: metaid_0000282
value: 2.2
name: K_IB

metaid_0000091
type: Parameter
constant: true
value: 5.0
name: V_MK

metaid_0000096
type: Parameter
constant: true
units: metaid_0000278
value: 45.0
name: E_Na_0

metaid_0000126
type: Parameter
constant: false
units: metaid_0000278
value: NaN
name: V_rest

metaid_0000033
type: Parameter
constant: true
units: metaid_0000288
value: 0.01
name: kd_mC

metaid_0000291
type: SBMLUnitsDef
unit: 865958
unit: 865946
unit: 865934
name: per_uM_per_h

865958
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 3600.0
kind: SECOND

865946
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE

865934
type: SBMLUnit
exponent: -1.0
scale: -6
multipler: 1.0
kind: MOLE

metaid_0000165
type: Parameter
constant: true
value: 0.4
name: V_phos

metaid_0000049
type: Parameter
constant: true
units: metaid_0000288
value: 0.12
name: kd_nc

metaid_0000133
type: Parameter
constant: true
value: 0.41

metaid_0000239
type: Reaction
reversible: true
fast: false
product: 866251
is: SBO:0000183
modifier: 866275
modifier: 866263
is version of: GO:0009299
kinetic law: 866287

866251
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000173

metaid_0000173
type: Species
name: M_P
encodes: O15055
initial amount: NaN
encodes: O15534
constant: false
has only substance units: false
boundary condition: false
initial concentration: 2.8
is version of: CHEBI:33699
is: SBO:0000278
encodes: P56645
in compartment: metaid_0000167

metaid_0000186
type: Species
has only substance units: false
initial concentration: 1.94
is version of: O00327
constant: false
initial amount: NaN
in compartment: metaid_0000169
boundary condition: false
name: B_N
is: SBO:0000252

metaid_0000169
type: Compartment
is part of: FMA:54527
is version of: GO:0005634
is: SBO:0000290
constant: true
size: 1.0
spatial dimensions: 3.0

metaid_0000140
type: Parameter
constant: true
units: metaid_0000279
value: 10.0
name: v_gk

metaid_0000264
type: Reaction
kinetic law: 867072
product: 867060
reactant: 867048
is version of: GO:0006468
is: SBO:0000216
fast: false
reversible: true

867060
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000185

metaid_0000185
type: Species
boundary condition: false
is version of: C00562
has only substance units: false
initial concentration: 0.48
is version of: O00327
constant: false
initial amount: NaN
is: SBO:0000252
in compartment: metaid_0000167
name: B_CP

867048
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000184

metaid_0000074
type: Parameter
constant: true
units: metaid_0000290
value: 0.6
name: vd_BN

metaid_0000156
type: Parameter
constant: true
value: -1.0
name: n_KCa

metaid_0000285
type: SBMLUnitsDef
unit: 865785
unit: 865772
name: per_uM

865785
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE

865772
type: SBMLUnit
exponent: -1.0
scale: -6
multipler: 1.0
kind: MOLE

metaid_0000274
type: SBMLUnitsDef
unit: 865590
name: nmole

865590
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000262
type: Reaction
kinetic law: 867000
reactant: 866988
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: true

866988
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000188

metaid_0000188
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.05
initial amount: NaN
in compartment: metaid_0000169
name: I_N

metaid_0000107
type: Parameter
constant: true
value: 4.0
name: K_Cl1

metaid_0000154
type: Parameter
constant: false
value: NaN
name: gK_Ca

metaid_0000088
type: Parameter
constant: false
units: dimensionless
value: NaN

metaid_0000118
type: Parameter
constant: false
units: metaid_0000278
value: NaN
name: theta_K

metaid_0000105
type: Parameter
constant: true
value: 8.75E-5

metaid_0000090
type: Parameter
constant: false
value: NaN
name: v_sPc

metaid_0000179
type: Species
initial amount: NaN
is version of: C00562
name: C_CP
initial concentration: 9.0
boundary condition: false
has version: Q16526
is: SBO:0000252
in compartment: metaid_0000167
has version: Q49AN0
has only substance units: false
constant: false

metaid_0000095
type: Parameter
constant: false
units: metaid_0000278
value: NaN
name: E_Na

metaid_0000164
type: Parameter
constant: true
value: 1.1

metaid_0000162
type: Parameter
constant: false
value: NaN

metaid_0000240
type: Reaction
kinetic law: 866311
reactant: 866299
is version of: GO:0006402
is: SBO:0000179
fast: false
reversible: true

866299
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000173

metaid_0000014
type: Parameter
constant: true
units: metaid_0000287
value: 5.0
name: K_2

metaid_0000287
type: SBMLUnitsDef
unit: 865835
unit: 865823
name: uM

865835
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE

865823
type: SBMLUnit
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE

metaid_0000132
type: Parameter
constant: false
value: NaN

metaid_0000130
type: Parameter
constant: true
units: metaid_0000278
value: 20.0

metaid_0000254
type: Reaction
kinetic law: 866759
product: 866747
reactant: 866735
fast: false
reversible: true

866747
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

metaid_0000181
type: Species
has part: Q16526
name: PC_N
constant: false
has only substance units: false
has part: Q49AN0
is: SBO:0000297
has part: O15534
in compartment: metaid_0000169
has part: P56645
boundary condition: false
initial concentration: 0.16
initial amount: NaN

866735
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000180

metaid_0000180
type: Species
is: SBO:0000297
name: PC_C
has part: Q16526
has part: O15534
has part: P56645
boundary condition: false
in compartment: metaid_0000167
initial concentration: 1.26
initial amount: NaN
has only substance units: false
constant: false

metaid_0000060
type: Parameter
constant: true
units: metaid_0000290
value: NaN
name: V3_PC

metaid_0000146
type: Parameter
constant: true
value: -1.0
name: n_ex2

metaid_0000261
type: Reaction
fast: false
product: 866964
reactant: 866952
kinetic law: 866976
reversible: true
is: SBO:0000526
is version of: GO:0006461
reactant: 866940

866964
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000188

866952
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

866940
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000186

metaid_0000042
type: Parameter
constant: true
units: metaid_0000290
value: NaN
name: V1_P

metaid_0000087
type: Parameter
constant: true
units: metaid_0000282
value: 3.0

metaid_0000104
type: Parameter
constant: false
units: metaid_0000278
value: NaN
name: E_Ca

metaid_0000080
type: Parameter
constant: true
units: metaid_0000290
value: 0.5

metaid_0000038
type: Parameter
constant: true
units: metaid_0000282
value: 0.4
name: K_mB

metaid_0000085
type: Parameter
constant: true
units: dimensionless
value: 0.2

metaid_0000102
type: Parameter
constant: false
units: metaid_0000278
value: NaN
name: E_L

metaid_0000283
type: SBMLUnitsDef
unit: 865733
unit: 865720
name: per_nM

865733
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE

865720
type: SBMLUnit
exponent: -1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000006
type: Parameter
constant: true
units: metaid_0000291
value: 3.3

metaid_0000004
type: Parameter
constant: true
units: dimensionless
value: 4.5

metaid_0000122
type: Parameter
constant: true
value: 0.3
name: P_Cl

metaid_0000253
type: Reaction
kinetic law: 866722
reactant: 866710
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: true

866710
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000179

metaid_0000079
type: Parameter
constant: true
units: dimensionless
value: 1.0

metaid_0000066
type: Parameter
constant: true
value: 0.12

metaid_0000251
type: Reaction
kinetic law: 866674
product: 866662
reactant: 866650
is: SBO:0000216
fast: false
reversible: true

866662
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000179

866650
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000177

metaid_0000267
type: Reaction
kinetic law: 867158
reactant: 867146
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: true

867146
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000185

metaid_0000077
type: Parameter
constant: true
units: metaid_0000290
value: 1.0

metaid_0000064
type: Parameter
constant: true
units: metaid_0000288
value: 0.1

metaid_0000093
type: Parameter
constant: true
value: 2.0

metaid_0000028
type: Parameter
constant: true
units: metaid_0000288
value: 0.01
name: kd_mP

metaid_00002991
type: SBMLUnitsDef
unit: 865995
unit: 865982
unit: 865970
name: per_nM_per_h

865995
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 3600.0
kind: SECOND

865982
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE

865970
type: SBMLUnit
exponent: -1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000256
type: Reaction
kinetic law: 866819
reactant: 866807
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: true

866807
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000180

metaid_0000160
type: Parameter
constant: true
units: metaid_0000278
value: 0.0

metaid_0000183
type: Species
in compartment: metaid_0000169
boundary condition: false
name: PC_NP
has only substance units: false
is: SBO:0000297
has part: Q16526
has part: P56645
has part: O15534
initial concentration: 0.091
constant: false
initial amount: NaN
has part: O15055

metaid_0000003
type: Parameter
constant: true
units: metaid_0000289
value: 0.09

metaid_0000289
type: SBMLUnitsDef
unit: 865884
unit: 865871
unit: 865859
name: uM_per_h

865884
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 3600.0
kind: SECOND

865871
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE

865859
type: SBMLUnit
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE

metaid_0000284
type: SBMLUnitsDef
unit: 865759
unit: 865746
name: per_nM_2

865759
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE

865746
type: SBMLUnit
exponent: -2.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000135
type: Parameter
constant: false
units: metaid_0000280
value: NaN
name: I_Na

metaid_0000019
type: Parameter
constant: true
units: metaid_0000287
value: 0.67
name: K_A

metaid_0000270
type: Reaction
kinetic law: 867242
reactant: 867230
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: true

867230
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000187

metaid_0000187
type: Species
name: B_NP
is: SBO:0000252
has only substance units: false
constant: false
boundary condition: false
initial concentration: 0.32
initial amount: NaN
is version of: O00327
in compartment: metaid_0000169

metaid_0000058
type: Parameter
constant: true
units: metaid_0000290
value: 0.1
name: V2_PC

metaid_0000243
type: Reaction
kinetic law: 866408
modifier: 866395
product: 866383
is version of: GO:0009299
is: SBO:0000183
fast: false
reversible: true

866383
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000175

metaid_0000017
type: Parameter
constant: true
units: metaid_0000287
value: 3.0
name: K_R_Ca

metaid_0000040
type: Parameter
constant: true
units: metaid_0000288
value: 0.6
name: ks_P

metaid_0000194
type: Species
initial concentration: 0.2
constant: false
initial amount: NaN
is: CHEBI:16865
has only substance units: false
is: SBO:0000327
boundary condition: false
in compartment: metaid_0000167
is: C00334

metaid_0000149
type: Parameter
constant: false
value: NaN
name: g_L

metaid_0000056
type: Parameter
constant: true
units: metaid_0000288
value: 0.2

metaid_0000010
type: Parameter
constant: true
units: metaid_0000289
value: 3.0E-4
name: V_M1

metaid_0000248
type: Reaction
fast: false
product: 866564
reversible: true
reactant: 866540
reactant: 866552
is version of: GO:0006461
kinetic law: 866576
is: SBO:0000526

866564
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000180

866540
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000176

866552
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000177

metaid_0000063
type: Parameter
constant: true
units: metaid_00002991
value: 0.5

metaid_0000083
type: Parameter
constant: true
value: 15.0

metaid_0000027
type: Parameter
constant: true
units: metaid_0000282
value: 0.31
name: K_mP

metaid_0000159
type: Parameter
constant: true
units: metaid_0000279
value: 12.3

metaid_0000246
type: Reaction
kinetic law: 866492
reactant: 866480
is: SBO:0000179
fast: false
reversible: true

866480
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000176

metaid_0000024
type: Parameter
constant: true
units: dimensionless
value: 4.0

metaid_0000111
type: Parameter
constant: true
value: 19.0
name: v_Cl2

metaid_0000127
type: Parameter
constant: true
value: 8.314
name: R_g

metaid_0000269
type: Reaction
kinetic law: 867218
reactant: 867206
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: true

867206
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000186

metaid_0000034
type: Parameter
constant: true
units: metaid_0000290
value: 1.0
name: v_sB

metaid_0000197
type: Species
is: CHEBI:9175
is: C01330
has only substance units: false
substance units: metaid_0000276
is: SBO:0000327
constant: false
initial amount: NaN
in compartment: metaid_0000167
boundary condition: true
initial concentration: NaN

metaid_0000276
type: SBMLUnitsDef
unit: 865616
name: millimole

865616
type: SBMLUnit
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE

metaid_0000125
type: Parameter
constant: false
value: NaN

metaid_0000009
type: Parameter
constant: true
units: dimensionless
value: 2.0

metaid_0000032
type: Parameter
constant: true
units: metaid_0000282
value: 0.4
name: K_mC

metaid_0000048
type: Parameter
constant: true
units: metaid_0000288
value: 1.6
name: ks_C

metaid_0000148
type: Parameter
constant: true
value: 4.4
name: V_ex2

W3 CDTF: Fri Apr 09 00:39:53 BST 2010

metaid_0000055
type: Parameter
constant: true
units: metaid_0000288
value: 0.45

metaid_0000238
type: Reaction
kinetic law: 866239
product: 866227
reactant: 866215
is version of: GO:0051209
is: SBO:0000185
fast: false
reversible: true

866227
type: SpeciesReference
stoichiometry: 0.001
species: metaid_0000170

866215
type: SpeciesReference
stoichiometry: 0.001
species: metaid_0000171

metaid_0000171
type: Species
initial amount: NaN
substance units: metaid_0000275
initial concentration: 0.1
is: C00076
boundary condition: false
in compartment: metaid_0000168
has only substance units: false
is: SBO:0000327
constant: false
is: CHEBI:29108

metaid_0000168
type: Compartment
has part: GO:0005739
has part: GO:0005783
is part of: FMA:54527
is: SBO:0000290
constant: true
size: 1.0
spatial dimensions: 3.0

metaid_0000053
type: Parameter
constant: true
units: metaid_0000282
value: 0.3
name: Kd

metaid_0000082
type: Parameter
constant: true
units: dimensionless
value: 1.9

metaid_0000198
type: Species
substance units: metaid_0000276
constant: false
is: SBO:0000327
initial concentration: 145.0
has only substance units: false
is: CHEBI:9175
in compartment: metaid_0000166
boundary condition: false
initial amount: NaN
is: C01330

metaid_0000069
type: Parameter
constant: true
value: 0.4

metaid_0000245
type: Reaction
kinetic law: 866468
modifier: 866456
product: 866444
is version of: GO:0006412
is: SBO:0000184
fast: false
reversible: true

866444
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000176

metaid_0000023
type: Parameter
constant: true
units: metaid_0000282
value: 0.15
name: K_C

metaid_0000155
type: Parameter
constant: true
value: 3.0
name: VK_Ca

metaid_0000191
type: Species
initial amount: NaN
initial concentration: 114.5
constant: false
is: C00698
boundary condition: false
is: SBO:0000327
is: CHEBI:17996
in compartment: metaid_0000166
substance units: metaid_0000276
has only substance units: false

metaid_0000119
type: Parameter
constant: false
value: NaN

metaid_0000021
type: Parameter
constant: true
units: metaid_0000290
value: 1.0
name: v_sP0

metaid_0000153
type: Parameter
constant: true
value: 22.0
name: K_Ca

metaid_0000259
type: Reaction
kinetic law: 866904
reactant: 866892
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: true

866892
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

metaid_0000117
type: Parameter
constant: false
units: metaid_0000278
value: NaN
name: theta_Na

metaid_0000281
type: SBMLUnitsDef
unit: 865681
name: nanoFarrad

865681
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: FARAD

metaid_0000124
type: Parameter
constant: false
value: NaN

metaid_0000031
type: Parameter
constant: true
units: metaid_0000290
value: 1.0
name: v_mC

metaid_0000163
type: Parameter
constant: true
value: 5.0

metaid_0000047
type: Parameter
constant: true
units: metaid_0000288
value: 0.2
name: k4

metaid_0000138
type: Parameter
constant: true
units: metaid_0000279
value: 9.7
name: g_K_0

metaid_0000161
type: Parameter
constant: false
value: NaN

metaid_0000045
type: Parameter
constant: true
units: metaid_0000282
value: 0.1
name: K_dp

metaid_0000131
type: Parameter
constant: false
units: metaid_0000278
value: NaN
name: V_reset

metaid_0000061
type: Parameter
constant: true
units: metaid_0000290
value: 0.1
name: V4_PC

metaid_0000237
type: Reaction
kinetic law: 866203
product: 866191
reactant: 866179
is version of: GO:0051209
is: SBO:0000185
fast: false
reversible: true

866191
type: SpeciesReference
stoichiometry: 0.001
species: metaid_0000170

866179
type: SpeciesReference
stoichiometry: 0.001
species: metaid_0000171

metaid_0000072
type: Parameter
constant: true
units: metaid_0000290
value: 0.5
name: V3_B

metaid_0000271
type: Reaction
kinetic law: 867267
product: 867254
is version of: GO:0032793
fast: false
reversible: true

867254
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000189

metaid_0000235
type: Reaction
kinetic law: 866131
product: 866119
is version of: GO:0005220
is: SBO:0000185
fast: false
reversible: true

866119
type: SpeciesReference
stoichiometry: 0.001
species: metaid_0000170

metaid_0000013
type: Parameter
constant: true
units: dimensionless
value: 2.2
name: n_M2

metaid_0000145
type: Parameter
constant: true
units: metaid_0000280
value: 5.7405E8
name: K_ex1

metaid_0000260
type: Reaction
kinetic law: 866928
reactant: 866916
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: true

866916
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000183

metaid_0000152
type: Parameter
constant: true
value: 2.2
name: n_Ca

metaid_0000086
type: Parameter
constant: true
units: metaid_0000282
value: 19.0

metaid_0000116
type: Parameter
constant: true
value: 1.0
name: K_PK

metaid_0000103
type: Parameter
constant: true
units: metaid_0000278
value: -29.0
name: E_L_0

metaid_0000150
type: Parameter
constant: false
value: NaN
name: g_Ca

metaid_0000084
type: Parameter
constant: true
value: 0.5

metaid_0000114
type: Parameter
constant: true
value: 1.9
name: v_PK

metaid_0000101
type: Parameter
constant: true
units: metaid_0000278
value: -97.0
name: E_K_0

metaid_0000037
type: Parameter
constant: true
units: metaid_0000290
value: 0.8
name: v_mB

metaid_0000121
type: Parameter
constant: true
value: 0.036
name: P_Na

metaid_0000277
type: SBMLUnitsDef
unit: 865629
name: hour

865629
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 3600.0
kind: SECOND

metaid_0000252
type: Reaction
kinetic law: 866698
reactant: 866686
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: true

866686
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000178

metaid_0000144
type: Parameter
constant: true
value: 2.5
name: n_ex1

metaid_0000078
type: Parameter
constant: true
units: metaid_0000282
value: 0.01

metaid_0000250
type: Reaction
kinetic law: 866637
reactant: 866625
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: true

866625
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000177

metaid_0000142
type: Parameter
constant: false
units: metaid_0000279
value: NaN

metaid_0000266
type: Reaction
kinetic law: 867133
reactant: 867121
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: true

867121
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000184

metaid_0000076
type: Parameter
constant: true
units: metaid_0000282
value: 0.01

metaid_0000158
type: Parameter
constant: false
units: metaid_0000280
value: NaN

metaid_0000273
type: Reaction
kinetic law: 867316
reactant: 867304
is version of: GO:0032801
is version of: GO:0004999
is: SBO:0000179
fast: false
reversible: true

867304
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000190

metaid_0000109
type: Parameter
constant: true
value: -0.2
name: n_Cl

metaid_0000100
type: Parameter
constant: false
units: metaid_0000278
value: NaN
name: E_K

metaid_0000099
type: Parameter
constant: true
units: kelvin
value: 22.0

metaid_0000092
type: Parameter
constant: true
value: 2.9
name: k_MK

metaid_0000097
type: Parameter
constant: true
units: kelvin
value: 37.0

metaid_0000120
type: Parameter
constant: true
value: 0.05
name: P_Ca

metaid_0000050
type: Parameter
constant: true
units: metaid_0000290
value: 0.6
name: V1_C

metaid_0000018
type: Parameter
constant: true
units: dimensionless
value: 4.2
name: p_A

metaid_0000242
type: Reaction
kinetic law: 866371
reactant: 866359
is version of: GO:0006402
is: SBO:0000179
fast: false
reversible: true

866359
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000174

metaid_0000016
type: Parameter
constant: true
units: dimensionless
value: 6.0
name: n_M3

metaid_0000134
type: Parameter
constant: true
units: metaid_0000278
value: 34.0

metaid_0000265
type: Reaction
kinetic law: 867109
product: 867097
reactant: 867084
fast: false
reversible: true

867097
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000186

867084
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000184

metaid_0000075
type: Parameter
constant: false
units: metaid_0000290
value: NaN
name: v_K

metaid_0000062
type: Parameter
constant: true
units: metaid_0000290
value: 0.7
name: vd_PCN

metaid_0000026
type: Parameter
constant: true
units: metaid_0000290
value: 1.1
name: v_mP

metaid_0000263
type: Reaction
kinetic law: 867036
modifier: 867024
product: 867012
is version of: GO:0006412
is: SBO:0000184
fast: false
reversible: true

867012
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000184

metaid_0000108
type: Parameter
constant: true
value: 15.5
name: v_Cl1

metaid_0000073
type: Parameter
constant: true
units: metaid_0000290
value: 0.2
name: V4_B

metaid_0000089
type: Parameter
constant: true
value: 0.08
name: K_D

metaid_0000106
type: Parameter
constant: false
value: NaN

metaid_0000268
type: Reaction
kinetic law: 867194
product: 867182
reactant: 867170
is version of: GO:0006468
is: SBO:0000216
fast: false
reversible: true

867182
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000187

867170
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000186

metaid_0000286
type: SBMLUnitsDef
unit: 865810
unit: 865797
name: mM

865810
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE

865797
type: SBMLUnit
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE

metaid_0000008
type: Parameter
constant: true
units: metaid_0000282
value: 0.02

metaid_0000241
type: Reaction
kinetic law: 866347
modifier: 866335
product: 866323
is version of: GO:0009299
is: SBO:0000183
fast: false
reversible: true

866323
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000174

metaid_0000015
type: Parameter
constant: true
units: metaid_0000289
value: 400.0
name: V_M3

metaid_0000192
type: Species
in compartment: metaid_0000167
initial amount: NaN
is: SBO:0000327
boundary condition: false
constant: false
has only substance units: false
initial concentration: 1.0
is: CHEBI:17996
substance units: metaid_0000276
is: C00698

metaid_0000147
type: Parameter
constant: true
units: metaid_0000285
value: 1.0
name: K_ex2

metaid_0000054
type: Parameter
constant: true
units: metaid_0000290
value: 0.7
name: v_dCC

metaid_0000255
type: Reaction
kinetic law: 866795
product: 866783
reactant: 866771
is version of: GO:0006468
is: SBO:0000216
fast: false
reversible: true

866783
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000182

866771
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000180

metaid_0000052
type: Parameter
constant: true
units: metaid_00002991
value: 0.7
name: v_dPC

metaid_0000081
type: Parameter
constant: false
units: hertz
value: NaN

metaid_0000068
type: Parameter
constant: true
units: metaid_0000290
value: 0.1
name: V2_B

metaid_0000244
type: Reaction
kinetic law: 866432
reactant: 866420
is version of: GO:0006402
is: SBO:0000179
fast: false
reversible: true

866420
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000175

metaid_0000022
type: Parameter
constant: true
units: metaid_0000290
value: 1.6
name: C_T

metaid_0000020
type: Parameter
constant: true
units: metaid_0000288
value: 0.001
name: k_f

metaid_0000039
type: Parameter
constant: true
units: metaid_0000288
value: 0.01
name: kd_mB

metaid_0000258
type: Reaction
kinetic law: 866880
product: 866868
reactant: 866856
is version of: GO:0006468
is: SBO:0000216
fast: false
reversible: true

866868
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000183

866856
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

metaid_0000195
type: Species
has only substance units: false
substance units: metaid_0000276
boundary condition: true
is: SBO:0000327
in compartment: metaid_0000167
is: C00238
is: CHEBI:29103
constant: false
initial amount: NaN
initial concentration: NaN

metaid_0000123
type: Parameter
constant: false
value: NaN
name: beta_a

metaid_0000007
type: Parameter
constant: true
units: dimensionless
value: 0.1

metaid_0000030
type: Parameter
constant: true
units: metaid_0000282
value: 0.6
name: K_sC

metaid_0000139
type: Parameter
constant: true
units: metaid_0000282
value: 10.0
name: K_gk

metaid_0000046
type: Parameter
constant: true
units: metaid_00002991
value: 0.4
name: k3

metaid_0000005
type: Parameter
constant: true
units: metaid_0000282
value: 4.5

metaid_0000137
type: Parameter
constant: false
units: metaid_0000279
value: NaN
name: g_K

metaid_0000110
type: Parameter
constant: true
value: 1.0
name: K_Cl2

metaid_0000044
type: Parameter
constant: true
units: metaid_0000290
value: 0.3
name: V2_P

metaid_0000236
type: Reaction
kinetic law: 866167
product: 866155
reactant: 866143
is version of: GO:0051208
is: SBO:0000185
fast: false
reversible: true

866155
type: SpeciesReference
stoichiometry: 0.001
species: metaid_0000171

866143
type: SpeciesReference
stoichiometry: 0.001
species: metaid_0000170

metaid_0000051
type: Parameter
constant: true
units: metaid_0000290
value: 0.1
name: V2_C

metaid_0000196
type: Species
boundary condition: false
substance units: metaid_0000276
is: SBO:0000327
is: C00238
in compartment: metaid_0000166
has only substance units: false
initial concentration: 1.0
is: CHEBI:29103
constant: false
initial amount: NaN

metaid_0000071
type: Parameter
constant: true
units: metaid_0000290
value: 0.5
name: vd_BC

metaid_0000067
type: Parameter
constant: true
units: metaid_0000290
value: 0.5
name: V1_B

metaid_0000234
type: Reaction
kinetic law: 866107
modifier: 866095
reactant: 866083
is version of: GO:0060401
is: SBO:0000185
fast: false
reversible: true

866083
type: SpeciesReference
stoichiometry: 0.001
species: metaid_0000170

metaid_0000012
type: Parameter
constant: true
units: metaid_0000289
value: 149.5
name: V_M2

metaid_0000065
type: Parameter
constant: true
units: metaid_0000290
value: 0.8
name: vd_IN

metaid_0000094
type: Parameter
constant: true
value: 2.0

metaid_0000029
type: Parameter
constant: true
units: metaid_0000290
value: 1.1
name: v_sC

metaid_0000151
type: Parameter
constant: true
value: 12.3
name: v_Ca

metaid_0000115
type: Parameter
constant: true
value: -2.0
name: n_PK

metaid_0000257
type: Reaction
kinetic law: 866844
reactant: 866831
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: true

866831
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000182

metaid_0000113
type: Parameter
constant: false
value: NaN
name: P_K

W3 CDTF: Wed Aug 31 21:01:44 BST 2011

ORG:
  orgname: EMBL-EBI
n:
  given: Lukas
  family: Endler