BIOMD0000000226
type: SBMLModel
species: 090967
parameter: 091544
reaction: 091353
species: 091178
species: 091092
species: 091018
reaction: 091463
parameter: 091532
reaction: 091380
species: 091146
reaction: 091338
length unit: length
parameter: 091582
parameter: 091590
parameter: 091570
species: 091167
species: 091124
curated: true
compartment: 090937
parameter: 091558
parameter: 091538
reaction: 091216
reaction: 091368
species: 091135
reaction: 091242
is derived from: BIOMD0000000139
is part of: mmu04660
reaction: 091200
occurs in: http://identifiers.org/taxonomy/10090
reaction: 091515
species: 090998
reaction: 091300
name: Radulescu2008_NFkB_hierarchy_M_14_25_28_Lipniacky
species: 091008
parameter: 091562
parameter: 091542
parameter: 091566
parameter: 091546
parameter: 091550
species: 091039
species: 090947
species: 091156
parameter: 091554
parameter: 091534
species: 091103
reaction: 091503
parameter: 091584
reaction: 091284
reaction: 091422
species: 091114
species: 090977
parameter: 091588
reaction: 091394
parameter: 091572
reaction: 091450
parameter: 091576
species: 091061
is version of: GO:0007249
reaction: 091491
reaction: 091256
reaction: 091325
time units: metaid_0000029
species: 091082
substance units: metaid_0000028
species: 090987
parameter: 091580
reaction: 091229
reaction: 091409
reaction: 091476
area units: metaid_0000005
species: 091189
species: 090957
parameter: 091564
species: 091028
volume units: metaid_0000069
parameter: 091568
parameter: 091548
is: MODEL7743386835
parameter: 091552

090967
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090937
name: sa12_degraded

090937
type: Compartment
is version of: GO:0005829
constant: true
size: 1.0
spatial dimensions: 3.0

091544
type: Parameter
constant: true
value: 0.1

091353
type: Reaction
kinetic law: 974770
product: 974758
product: 974746
reactant: 974734
is version of: GO:0043241
fast: false
reversible: false

974758
type: SpeciesReference
stoichiometry: 1.0
species: 091050

091050
type: Species
has part: Q60680
initial amount: 0.0
boundary condition: false
has part: O88522
in compartment: 090937
has only substance units: false
name: IKKa
initial concentration: NaN
has part: O88351
constant: false

974746
type: SpeciesReference
stoichiometry: 1.0
species: 091167

091167
type: Species
is version of: P25799
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090937
name: NFkB

974734
type: SpeciesReference
stoichiometry: 1.0
species: 091114

091114
type: Species
name: NFkB/Ikb_alpha/IKKa
has part: Q60680
initial amount: 0.0
constant: false
has only substance units: false
has part: P25799
initial concentration: NaN
in compartment: 090937
has part: O88522
has part: Q9Z1E3
boundary condition: false
has part: O88351

091178
type: Species
is version of: P25799
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090938
name: NFkB

090938
type: Compartment
is version of: GO:0005634
constant: true
size: 1.0
spatial dimensions: 3.0
name: nucleus

091092
type: Species
initial amount: 0.0
constant: false
has part: O88351
boundary condition: false
has part: Q60680
name: IKKa/IKBa
has part: Q9Z1E3
has part: O88522
in compartment: 090937
initial concentration: NaN
has only substance units: false

091018
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090937
name: sa444_degraded

091463
type: Reaction
kinetic law: 975106
product: 975094
reactant: 975082
fast: false
reversible: false

975094
type: SpeciesReference
stoichiometry: 1.0
species: 091082

091082
type: Species
initial amount: 0.06
name: NFkB:IkB_alpha
has part: P25799
constant: false
in compartment: 090937
has part: Q9Z1E3
boundary condition: false
has only substance units: false
initial concentration: NaN

975082
type: SpeciesReference
stoichiometry: 5.0
species: 091146

091146
type: Species
in compartment: 090938
initial concentration: NaN
name: NFkB/IkB_alpha
boundary condition: false
constant: false
has part: Q9Z1E3
has only substance units: false
initial amount: 0.0
has part: P25799

091532
type: Parameter
constant: true
value: 1.25E-4

091380
type: Reaction
kinetic law: 974854
product: 974842
product: 974830
reactant: 974818
is version of: GO:0006412
fast: false
reversible: false

974842
type: SpeciesReference
stoichiometry: 1.0
species: 090998

090998
type: Species
is version of: ENSMUST00000019997
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090937
name: mRNAA20

974830
type: SpeciesReference
stoichiometry: 1.0
species: 091008

091008
type: Species
is version of: Q60769
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090937
name: A20

974818
type: SpeciesReference
stoichiometry: 1.0
species: 090998

091338
type: Reaction
kinetic law: 974722
product: 974710
reactant: 974698
reactant: 974686
is version of: GO:0006461
fast: false
reversible: false

974710
type: SpeciesReference
stoichiometry: 1.0
species: 091114

974698
type: SpeciesReference
stoichiometry: 1.0
species: 091082

974686
type: SpeciesReference
stoichiometry: 1.0
species: 091050

091582
type: Parameter
constant: true
value: 5.0E-4

091590
type: Parameter
constant: true
value: 5.0E-7

091570
type: Parameter
constant: true
value: 3.0E-4

091124
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090937
name: sa96_degraded

091558
type: Parameter
constant: true
value: 18.4

091538
type: Parameter
constant: true
value: 0.0015

091216
type: Reaction
kinetic law: 974350
product: 974338
reactant: 974326
is version of: GO:0006402
fast: false
reversible: false

974338
type: SpeciesReference
stoichiometry: 1.0
species: 090967

974326
type: SpeciesReference
stoichiometry: 1.0
species: 090977

090977
type: Species
is version of: ENSMUST00000021413
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090937
name: mRNAIKBA

091368
type: Reaction
kinetic law: 974806
product: 974794
reactant: 974782
is version of: GO:0030163
fast: false
reversible: false

974794
type: SpeciesReference
stoichiometry: 1.0
species: 091018

974782
type: SpeciesReference
stoichiometry: 1.0
species: 091028

091028
type: Species
name: IKKi
has only substance units: false
in compartment: 090937
has part: Q60680
has part: O88522
initial concentration: NaN
constant: false
has part: O88351
boundary condition: false
initial amount: 0.0

091135
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090937
name: sa97_degraded

091242
type: Reaction
kinetic law: 974434
product: 974422
product: 974410
reactant: 974398
is version of: GO:0006412
fast: false
reversible: false

974422
type: SpeciesReference
stoichiometry: 1.0
species: 090977

974410
type: SpeciesReference
stoichiometry: 1.0
species: 091156

091156
type: Species
is version of: Q9Z1E3
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090937
name: IkB_alpha

974398
type: SpeciesReference
stoichiometry: 1.0
species: 090977

091200
type: Reaction
kinetic law: 974314
modifier: 974302
product: 974290
reactant: 974278
is version of: GO:0006406
fast: false
reversible: false

974290
type: SpeciesReference
stoichiometry: 1.0
species: 090977

974278
type: SpeciesReference
stoichiometry: 1.0
species: 090947

090947
type: Species
is version of: Q9Z1E3
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090938
name: IKBA

091515
type: Reaction
kinetic law: 975262
product: 975250
reactant: 975238
fast: false
reversible: false

975250
type: SpeciesReference
stoichiometry: 5.0
species: 091189

091189
type: Species
is version of: Q9Z1E3
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090938
name: IkB_alpha

975238
type: SpeciesReference
stoichiometry: 1.0
species: 091156

091300
type: Reaction
kinetic law: 974602
product: 974590
reactant: 974578
is version of: GO:0030163
fast: false
reversible: false

974590
type: SpeciesReference
stoichiometry: 1.0
species: 091039

091039
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090937
name: sa19_degraded

974578
type: SpeciesReference
stoichiometry: 1.0
species: 091061

091061
type: Species
initial amount: 0.0
has part: Q60680
has part: O88522
name: IKKn
initial concentration: NaN
has part: O88351
boundary condition: false
constant: false
has only substance units: false
in compartment: 090937

091562
type: Parameter
constant: true
value: 0.0025

091542
type: Parameter
constant: true
value: 0.2

091566
type: Parameter
constant: true
value: 0.5

091546
type: Parameter
constant: true
value: 1.0

091550
type: Parameter
constant: true
value: 1.25E-4

091554
type: Parameter
constant: true
value: 18.4

091534
type: Parameter
constant: false
value: 2.5E-6

091103
type: Species
has part: O88522
constant: true
has part: O88351
has part: Q60680
has only substance units: false
boundary condition: true
initial amount: 0.0
initial concentration: NaN
in compartment: 090938
name: IKK

091503
type: Reaction
kinetic law: 975226
product: 975214
reactant: 975202
is version of: GO:0030163
fast: false
reversible: false

975214
type: SpeciesReference
stoichiometry: 1.0
species: 091135

975202
type: SpeciesReference
stoichiometry: 1.0
species: 091008

091584
type: Parameter
constant: true
value: 4.0E-4

091284
type: Reaction
kinetic law: 974566
modifier: 974554
product: 974542
reactant: 974530
is version of: GO:0043241
fast: false
reversible: false

974542
type: SpeciesReference
stoichiometry: 1.0
species: 091167

974530
type: SpeciesReference
stoichiometry: 1.0
species: 091082

091422
type: Reaction
kinetic law: 974986
product: 974974
reactant: 974962
reactant: 974950
is version of: GO:0006461
fast: false
reversible: false

974974
type: SpeciesReference
stoichiometry: 1.0
species: 091082

974962
type: SpeciesReference
stoichiometry: 1.0
species: 091167

974950
type: SpeciesReference
stoichiometry: 1.0
species: 091156

091588
type: Parameter
constant: true
value: 0.0

091394
type: Reaction
kinetic law: 974902
modifier: 974890
product: 974878
reactant: 974866
fast: false
reversible: false

974878
type: SpeciesReference
stoichiometry: 1.0
species: 091028

974866
type: SpeciesReference
stoichiometry: 1.0
species: 091050

091572
type: Parameter
constant: true
value: 5.0E-7

091450
type: Reaction
kinetic law: 975070
product: 975058
reactant: 975046
fast: false
reversible: false

975058
type: SpeciesReference
stoichiometry: 5.0
species: 091178

975046
type: SpeciesReference
stoichiometry: 1.0
species: 091167

091576
type: Parameter
constant: true
value: 1.0E-4

091491
type: Reaction
kinetic law: 975190
product: 975178
reactant: 975166
is version of: GO:0006402
fast: false
reversible: false

975178
type: SpeciesReference
stoichiometry: 1.0
species: 091124

975166
type: SpeciesReference
stoichiometry: 1.0
species: 090998

091256
type: Reaction
kinetic law: 974482
modifier: 974470
product: 974458
reactant: 974446
is version of: GO:0006406
fast: false
reversible: false

974458
type: SpeciesReference
stoichiometry: 1.0
species: 090998

974446
type: SpeciesReference
stoichiometry: 1.0
species: 090987

090987
type: Species
is version of: Q60769
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090938
name: A20

091325
type: Reaction
kinetic law: 974674
product: 974662
reactant: 974650
is version of: GO:0043241
fast: false
reversible: false

974662
type: SpeciesReference
stoichiometry: 1.0
species: 091050

974650
type: SpeciesReference
stoichiometry: 1.0
species: 091092

091580
type: Parameter
constant: true
value: 0.001

091229
type: Reaction
kinetic law: 974386
product: 974374
reactant: 974362
is version of: GO:0030163
fast: false
reversible: false

974374
type: SpeciesReference
stoichiometry: 1.0
species: 090957

090957
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090937
name: sa13_degraded

974362
type: SpeciesReference
stoichiometry: 1.0
species: 091156

091409
type: Reaction
kinetic law: 974938
product: 974926
reactant: 974914
fast: false
reversible: false

974926
type: SpeciesReference
stoichiometry: 1.0
species: 091061

974914
type: SpeciesReference
stoichiometry: 1.0
species: 091103

091476
type: Reaction
kinetic law: 975154
product: 975142
reactant: 975130
reactant: 975118
is version of: GO:0006461
fast: false
reversible: false

975142
type: SpeciesReference
stoichiometry: 1.0
species: 091146

975130
type: SpeciesReference
stoichiometry: 1.0
species: 091189

975118
type: SpeciesReference
stoichiometry: 1.0
species: 091178

091564
type: Parameter
constant: true
value: 0.0

091568
type: Parameter
constant: true
value: 4.0E-4

091548
type: Parameter
constant: true
value: 0.1

091552
type: Parameter
constant: true
value: 2.0E-5

091556
type: Parameter
constant: true
value: 0.0

091536
type: Parameter
constant: true
value: 0.1

091436
type: Reaction
kinetic law: 975034
product: 975022
reactant: 975010
reactant: 974998
is version of: GO:0006461
fast: false
reversible: false

975022
type: SpeciesReference
stoichiometry: 1.0
species: 091092

975010
type: SpeciesReference
stoichiometry: 1.0
species: 091050

974998
type: SpeciesReference
stoichiometry: 1.0
species: 091156

091586
type: Parameter
constant: true
value: 0.01

091312
type: Reaction
kinetic law: 974638
product: 974626
reactant: 974614
is version of: GO:0030163
fast: false
reversible: false

974626
type: SpeciesReference
stoichiometry: 1.0
species: 091071

091071
type: Species
constant: true
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 090937
name: sa20_degraded

974614
type: SpeciesReference
stoichiometry: 1.0
species: 091050

091271
type: Reaction
kinetic law: 974518
product: 974506
reactant: 974494
fast: false
reversible: false

974506
type: SpeciesReference
stoichiometry: 1.0
species: 091050

974494
type: SpeciesReference
stoichiometry: 1.0
species: 091061

W3 CDTF: Fri Mar 09 11:42:09 GMT 2012

091574
type: Parameter
constant: true
value: 0.0

091529
type: Parameter
constant: true
value: 0.0025

091578
type: Parameter
constant: true
value: 0.5

091560
type: Parameter
constant: true
value: 0.0

091540
type: Parameter
constant: true
value: 1.25E-4

W3 CDTF: Fri Feb 27 16:28:12 GMT 2009

ORG:
  orgname: IRMAR and IRISA/INRIA, University of Rennes 1
n:
  given: Ovidiu
  family: Radulescu

ORG:
  orgname: EMBL-EBI
n:
  given: Vijayalakshmi
  family: Chelliah