BIOMD0000000223
type: SBMLModel
parameter: metaid_0000069
reaction: metaid_0000388
parameter: metaid_0000016
units def: metaid_0000393
parameter: metaid_0000098
parameter: metaid_0000035
reaction: metaid_0000321
rule: metaid_0000264
parameter: metaid_0000014
rule: metaid_0000271
reaction: metaid_0000328
reaction: metaid_0000330
parameter: metaid_0000128
parameter: metaid_0000071
species: metaid_0000243
rule: metaid_0000258
parameter: metaid_0000058
species: metaid_0000227
species: metaid_0000218
rule: metaid_0000267
species: metaid_0000178
species: metaid_0000169
rule: metaid_0000260
reaction: metaid_0000337
parameter: metaid_0000088
name: Borisov2009_EGF_Insulin_Crosstalk
species: metaid_0000211
species: metaid_0000202
parameter: metaid_0000076
parameter: metaid_0000161
parameter: metaid_0000092
rule: metaid_0000256
parameter: metaid_0000004
parameter: metaid_0000080
parameter: metaid_0000086
parameter: metaid_0000074
parameter: metaid_0000118
parameter: metaid_0000023
reaction: metaid_0000348
parameter: metaid_0000090
parameter: metaid_0000048
reaction: metaid_0000392
reaction: metaid_0000380
parameter: metaid_0000036
reaction: metaid_0000316
reaction: metaid_0000358
parameter: metaid_0000116
volume units: metaid_0000069
reaction: metaid_0000304
reaction: metaid_0000346
reaction: metaid_0000297
parameter: metaid_0000109
parameter: metaid_0000097
species: metaid_0000239
species: metaid_0000195
rule: metaid_0000279
reaction: metaid_0000320
species: metaid_0000203
parameter: metaid_0000107
parameter: metaid_0000095
parameter: metaid_0000083
units def: metaid_0000398
species: metaid_0000170
parameter: metaid_0000064
reaction: metaid_0000383
rule: metaid_0000268
parameter: metaid_0000062
reaction: metaid_0000336
parameter: metaid_0000123
compartment: metaid_0000166
reaction: metaid_0000285
reaction: metaid_0000334
parameter: metaid_0000085
species: metaid_0000231
parameter: metaid_0000073
species: metaid_0000215
species: metaid_0000206
species: metaid_0000171
rule: metaid_0000255

metaid_0000069
type: Parameter
constant: true
units: metaid_0000395
value: 2.5

metaid_0000395
type: SBMLUnitsDef
unit: 886640
unit: 886628
name: nM

886640
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE

886628
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000388
type: Reaction
reversible: false
fast: false
product: 891731
product: 891719
modifier: 891767
modifier: 891755
modifier: 891743
kinetic law: 891779
reactant: 891707

891731
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000184

metaid_0000184
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000165
type: Compartment
is: GO:0005623
constant: true
size: 1.0
spatial dimensions: 3.0
name: cell

891719
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

metaid_0000181
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 50.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000221
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000204
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000203
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

891707
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000186

metaid_0000186
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000016
type: Parameter
constant: true
units: metaid_0000397
value: 200.0

metaid_0000397
type: SBMLUnitsDef
unit: 886713
unit: 886701
unit: 886689
name: nM per sec

886713
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND

886701
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE

886689
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000393
type: SBMLUnitsDef
unit: 886604
name: nanomole

886604
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000098
type: Parameter
constant: true
units: metaid_0000395
value: 50.0

metaid_0000035
type: Parameter
constant: true
units: metaid_0000398
value: 0.1066

metaid_0000398
type: SBMLUnitsDef
unit: 886750
unit: 886737
unit: 886725
name: per nM per s

886750
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND

886737
type: SBMLUnit
exponent: -1.0
scale: -9
multipler: 1.0
kind: MOLE

886725
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE

metaid_0000321
type: Reaction
kinetic law: 888451
product: 888439
reactant: 888427
reactant: 888415
fast: false
reversible: true

888439
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000195

metaid_0000195
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

888427
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000193

metaid_0000193
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

888415
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000179

metaid_0000179
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 200.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000014
type: Parameter
constant: true
units: metaid_0000398
value: 6.66E-4

metaid_0000328
type: Reaction
kinetic law: 888787
product: 888775
reactant: 888763
reactant: 888751
fast: false
reversible: true

888775
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000202

metaid_0000202
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

888763
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000200

metaid_0000200
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

888751
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000179

metaid_0000330
type: Reaction
kinetic law: 888884
product: 888872
reactant: 888859
reactant: 888847
fast: false
reversible: true

888872
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000203

888859
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000200

888847
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000196

metaid_0000196
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 300.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000128
type: Parameter
constant: true
units: metaid_0000396
value: 0.166

metaid_0000396
type: SBMLUnitsDef
unit: 886676
name: per second

886676
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND

metaid_0000071
type: Parameter
constant: true
units: metaid_0000395
value: 66666.0

metaid_0000243
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000058
type: Parameter
constant: true
units: metaid_0000396
value: 0.666

metaid_0000227
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000218
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000178
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000169
type: Species
has part: P01133
has part: P00533
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000337
type: Reaction
modifier: 889244
modifier: 889256
reversible: false
modifier: 889268
kinetic law: 889292
fast: false
reactant: 889208
modifier: 889232
modifier: 889280
product: 889220

metaid_0000194
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000201
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

889208
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000206

metaid_0000206
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 150.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000173
type: Species
has part: P00533
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

889220
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000226

metaid_0000226
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000088
type: Parameter
constant: true
units: metaid_0000396
value: 2.5

metaid_0000211
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000076
type: Parameter
constant: true
units: metaid_0000395
value: 150.0

metaid_0000161
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000092
type: Parameter
constant: true
units: metaid_0000395
value: 10.0

metaid_0000004
type: Parameter
constant: true
units: metaid_0000398
value: 0.068

metaid_0000080
type: Parameter
constant: true
units: metaid_0000395
value: 20.0

metaid_0000086
type: Parameter
constant: true
units: metaid_0000395
value: 50.0

metaid_0000074
type: Parameter
constant: true
units: metaid_0000396
value: 0.666

metaid_0000118
type: Parameter
constant: true
units: metaid_0000396
value: 0.666

metaid_0000023
type: Parameter
constant: true
units: metaid_0000398
value: 0.00933

metaid_0000348
type: Reaction
kinetic law: 889868
modifier: 889857
product: 889845
reactant: 889833
fast: false
reversible: false

metaid_0000223
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

889845
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000210

metaid_0000210
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 400.0
initial amount: NaN
in compartment: metaid_0000165

889833
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000211

metaid_0000090
type: Parameter
constant: true
units: metaid_0000395
value: 400.0

metaid_0000048
type: Parameter
constant: true
units: metaid_0000395
value: 10.0

metaid_0000392
type: Reaction
kinetic law: 891985
product: 891972
reactant: 891960
fast: false
reversible: false

891972
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000232

metaid_0000232
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

891960
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000250

metaid_0000250
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000380
type: Reaction
kinetic law: 891262
product: 891250
product: 891238
reactant: 891226
fast: false
reversible: false

891250
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000198

metaid_0000198
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 225.0
initial amount: NaN
in compartment: metaid_0000165

891238
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000179

891226
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000244

metaid_0000244
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000036
type: Parameter
constant: true
units: metaid_0000395
value: 3.75

metaid_0000316
type: Reaction
kinetic law: 888210
product: 888198
reactant: 888186
fast: false
reversible: false

888198
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000191

metaid_0000191
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 518.0
initial amount: NaN
in compartment: metaid_0000165

888186
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000234

metaid_0000234
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000358
type: Reaction
kinetic law: 890325
product: 890313
reactant: 890301
fast: false
reversible: false

890313
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000170

metaid_0000170
type: Species
is version of: P00533
is version of: P01133
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

890301
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000235

metaid_0000235
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000116
type: Parameter
constant: true
units: dimensionless
value: 0.5

metaid_0000304
type: Reaction
kinetic law: 887717
product: 887704
reactant: 887692
reactant: 887680
fast: false
reversible: true

887704
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000185

metaid_0000185
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

887692
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000184

887680
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000179

metaid_0000346
type: Reaction
kinetic law: 889785
modifier: 889773
modifier: 889761
product: 889749
reactant: 889736
fast: false
reversible: false

metaid_0000220
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

889749
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000223

889736
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000211

metaid_0000297
type: Reaction
kinetic law: 887437
product: 887425
reactant: 887413
fast: false
reversible: false

887425
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000174

metaid_0000174
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 270.0
initial amount: NaN
in compartment: metaid_0000165

887413
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000175

metaid_0000175
type: Species
has part: P00533
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000109
type: Parameter
constant: true
units: metaid_0000398
value: 0.00666

metaid_0000097
type: Parameter
constant: true
units: metaid_0000396
value: 0.133

metaid_0000239
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000320
type: Reaction
kinetic law: 888403
product: 888391
reactant: 888379
reactant: 888367
fast: false
reversible: true

888391
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000194

888379
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000193

888367
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000172

metaid_0000172
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 200.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000107
type: Parameter
constant: true
units: metaid_0000397
value: 23.33

metaid_0000095
type: Parameter
constant: true
units: metaid_0000398
value: 1.0E-6

metaid_0000083
type: Parameter
constant: true
units: metaid_0000396
value: 5.33

metaid_0000064
type: Parameter
constant: true
units: metaid_0000397
value: 333.0

metaid_0000383
type: Reaction
kinetic law: 891406
product: 891394
product: 891382
reactant: 891370
fast: false
reversible: false

891394
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000198

891382
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000196

891370
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000247

metaid_0000247
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000062
type: Parameter
constant: true
units: dimensionless
value: 1.0E-4

metaid_0000336
type: Reaction
kinetic law: 889196
product: 889184
reactant: 889172
fast: false
reversible: false

889184
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000216

metaid_0000216
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

889172
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

metaid_0000205
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000123
type: Parameter
constant: true
units: metaid_0000395
value: 5000.0

metaid_0000166
type: Compartment
constant: true
size: 34.0
spatial dimensions: 3.0
name: extracellular space

metaid_0000285
type: Reaction
kinetic law: 886919
product: 886907
reactant: 886895
reactant: 886883
fast: false
reversible: true

886907
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000173

886895
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000172

886883
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000171

metaid_0000171
type: Species
is version of: P00533
is version of: P01133
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000334
type: Reaction
kinetic law: 889076
product: 889064
reactant: 889052
reactant: 889040
fast: false
reversible: true

889064
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000221

889052
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000204

889040
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000172

metaid_0000085
type: Parameter
constant: true
units: metaid_0000396
value: 20000.0

metaid_0000231
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000073
type: Parameter
constant: true
units: metaid_0000395
value: 100.0

metaid_0000215
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000339
type: Reaction
kinetic law: 889424
product: 889412
reactant: 889400
reactant: 889388
fast: false
reversible: false

889412
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000227

889400
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000226

889388
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000179

metaid_0000144
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000371
type: Reaction
kinetic law: 890830
product: 890818
product: 890807
reactant: 890794
fast: false
reversible: true

890818
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000247

890807
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

890794
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000203

metaid_0000288
type: Reaction
kinetic law: 887052
product: 887040
product: 887028
reactant: 887016
fast: false
reversible: true

887040
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000177

metaid_0000177
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

887028
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000171

887016
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000176

metaid_0000176
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

ORG:
  orgname: EMBL-EBI
n:
  given: Lukas
  family: Endler

metaid_0000106
type: Parameter
constant: true
units: metaid_0000395
value: 500.0

metaid_0000343
type: Reaction
kinetic law: 889640
modifier: 889628
product: 889616
reactant: 889604
fast: false
reversible: false

metaid_0000217
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

889616
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000220

889604
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000209

metaid_0000209
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 200.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000019
type: Parameter
constant: true
units: metaid_0000398
value: 0.00666

metaid_0000111
type: Parameter
constant: true
units: metaid_0000396
value: 4.66

metaid_0000104
type: Parameter
constant: true
units: metaid_0000395
value: 500.0

metaid_0000199
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000207
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000299
type: Reaction
kinetic law: 887511
product: 887499
reactant: 887486
fast: false
reversible: false

887499
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000219

metaid_0000219
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

887486
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000178

metaid_0000155
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000061
type: Parameter
constant: true
units: metaid_0000396
value: 3333.0

metaid_0000134
type: Parameter
constant: true
units: metaid_0000397
value: 333.0

metaid_0000183
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000122
type: Parameter
constant: true
units: metaid_0000396
value: 0.0466

metaid_0000052
type: Parameter
constant: true
units: metaid_0000395
value: 100000.0

metaid_0000132
type: Parameter
constant: true
units: metaid_0000395
value: 50.0

metaid_0000120
type: Parameter
constant: true
units: metaid_0000395
value: 100.0

metaid_0000009
type: Parameter
constant: true
units: metaid_0000398
value: 6.66E-4

metaid_0000050
type: Parameter
constant: true
units: metaid_0000395
value: 150.0

metaid_0000079
type: Parameter
constant: true
units: metaid_0000398
value: 0.01

metaid_0000331
type: Reaction
kinetic law: 888932
product: 888920
product: 888908
reactant: 888896
fast: false
reversible: false

888920
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000199

888908
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000196

888896
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000203

metaid_0000164
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000007
type: Parameter
constant: true
units: metaid_0000395
value: 15.0

metaid_0000309
type: Reaction
kinetic law: 887933
product: 887921
reactant: 887909
fast: false
reversible: false

887921
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000187

metaid_0000187
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 300.0
initial amount: NaN
in compartment: metaid_0000165

887909
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000190

metaid_0000190
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000287
type: Reaction
kinetic law: 887004
product: 886992
reactant: 886980
fast: false
reversible: false

886992
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000176

886980
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000175

metaid_0000039
type: Parameter
constant: true
units: metaid_0000395
value: 10.0

metaid_0000365
type: Reaction
kinetic law: 890541
product: 890529
product: 890517
reactant: 890505
fast: false
reversible: true

890529
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000241

metaid_0000241
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

890517
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

890505
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000194

metaid_0000325
type: Reaction
kinetic law: 888655
modifier: 888643
modifier: 888631
product: 888619
reactant: 888607
fast: false
reversible: false

888619
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000200

888607
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000199

metaid_0000110
type: Parameter
constant: true
units: metaid_0000395
value: 100.0

metaid_0000040
type: Parameter
constant: true
units: metaid_0000397
value: 333.0

metaid_0000154
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000101
type: Parameter
constant: true
units: metaid_0000396
value: 0.333

metaid_0000067
type: Parameter
constant: true
units: metaid_0000395
value: 1.0

metaid_0000386
type: Reaction
modifier: 891575
modifier: 891563
reactant: 891526
product: 891551
modifier: 891599
modifier: 891587
kinetic law: 891611
fast: false
product: 891538
reversible: false

metaid_0000197
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

891526
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000229

metaid_0000229
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

891551
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000199

891538
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

metaid_0000152
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000029
type: Parameter
constant: true
units: metaid_0000395
value: 0.029412

metaid_0000252
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: metaid_0000165

metaid_0000236
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000027
type: Parameter
constant: true
units: metaid_0000396
value: 1.85E-4

metaid_0000353
type: Reaction
kinetic law: 890109
modifier: 890097
product: 890085
reactant: 890073
fast: false
reversible: true

metaid_0000230
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

890085
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000228

metaid_0000228
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

890073
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000214

metaid_0000214
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000313
type: Reaction
kinetic law: 888077
product: 888065
reactant: 888053
fast: false
reversible: false

888065
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000187

888053
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000188

metaid_0000188
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000341
type: Reaction
kinetic law: 889520
modifier: 889508
product: 889496
reactant: 889484
fast: false
reversible: false

889496
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000217

889484
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000208

metaid_0000208
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000301
type: Reaction
kinetic law: 887583
product: 887571
reactant: 887559
fast: false
reversible: false

887571
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

887559
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000182

metaid_0000182
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000308
type: Reaction
kinetic law: 887897
product: 887885
product: 887873
reactant: 887861
fast: false
reversible: true

887885
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000190

887873
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000184

887861
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000189

metaid_0000189
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000376
type: Reaction
kinetic law: 891070
product: 891058
product: 891046
reactant: 891034
fast: false
reversible: false

891058
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000196

891046
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000187

891034
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000242

metaid_0000242
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000364
type: Reaction
kinetic law: 890493
product: 890481
product: 890469
reactant: 890457
fast: false
reversible: true

890481
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000240

metaid_0000240
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

890469
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

890457
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000195

metaid_0000324
type: Reaction
kinetic law: 888595
product: 888583
reactant: 888571
reactant: 888559
fast: false
reversible: true

888583
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000199

888571
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

888559
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000198

metaid_0000374
type: Reaction
kinetic law: 890974
product: 890962
product: 890950
reactant: 890938
fast: false
reversible: false

890962
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000187

890950
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000179

890938
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000240

metaid_0000322
type: Reaction
kinetic law: 888499
product: 888487
reactant: 888475
reactant: 888463
fast: false
reversible: true

888487
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000197

888475
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000196

888463
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000193

metaid_0000046
type: Parameter
constant: true
units: metaid_0000395
value: 50.0

metaid_0000248
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000129
type: Parameter
constant: true
units: metaid_0000395
value: 300.0

metaid_0000034
type: Parameter
constant: true
units: metaid_0000395
value: 2000000.0

metaid_0000212
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000327
type: Reaction
kinetic law: 888739
product: 888727
reactant: 888715
reactant: 888703
fast: false
reversible: true

888727
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000201

888715
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000200

888703
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000172

metaid_0000013
type: Parameter
constant: true
units: metaid_0000396
value: 0.333

metaid_0000139
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000369
type: Reaction
kinetic law: 890734
product: 890722
product: 890709
reactant: 890697
fast: false
reversible: true

890722
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000245

metaid_0000245
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

890709
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

890697
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000201

metaid_0000127
type: Parameter
constant: true
units: metaid_0000396
value: 6.66E-5

metaid_0000057
type: Parameter
constant: true
units: metaid_0000395
value: 1000.0

metaid_0000011
type: Parameter
constant: true
units: metaid_0000395
value: 10.0

metaid_0000352
type: Reaction
kinetic law: 890061
modifier: 890049
modifier: 890037
product: 890025
reactant: 890013
fast: false
reversible: true

890025
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000230

890013
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000215

metaid_0000312
type: Reaction
kinetic law: 888041
product: 888029
reactant: 888017
fast: false
reversible: false

888029
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

888017
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000186

metaid_0000055
type: Parameter
constant: true
units: metaid_0000395
value: 1.0

metaid_0000340
type: Reaction
kinetic law: 889472
modifier: 889460
product: 889448
reactant: 889436
fast: false
reversible: false

889448
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000208

889436
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000207

metaid_0000300
type: Reaction
kinetic law: 887547
product: 887535
reactant: 887523
fast: false
reversible: false

887535
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000179

887523
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000180

metaid_0000180
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000350
type: Reaction
kinetic law: 889965
modifier: 889953
product: 889941
reactant: 889928
fast: false
reversible: false

metaid_0000225
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

889941
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000214

889928
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000213

metaid_0000213
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000249
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000291
type: Reaction
kinetic law: 887185
product: 887173
product: 887161
reactant: 887148
fast: false
reversible: true

887173
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000219

887161
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000171

887148
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000178

metaid_0000024
type: Parameter
constant: true
units: metaid_0000395
value: 12.45

metaid_0000148
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000091
type: Parameter
constant: true
units: metaid_0000396
value: 3.33

metaid_0000359
type: Reaction
kinetic law: 890361
product: 890349
reactant: 890337
fast: false
reversible: false

890349
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000236

890337
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000184

metaid_0000117
type: Parameter
constant: true
units: metaid_0000395
value: 100.0

metaid_0000022
type: Parameter
constant: false
units: metaid_0000398
value: 0.0

metaid_0000347
type: Reaction
kinetic law: 889821
product: 889809
reactant: 889797
fast: false
reversible: false

889809
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000211

889797
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000223

metaid_0000224
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 150.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000391
type: Reaction
kinetic law: 891948
modifier: 891936
product: 891924
reactant: 891911
fast: false
reversible: true

891924
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000250

891911
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000200

metaid_0000315
type: Reaction
kinetic law: 888174
modifier: 888162
modifier: 888150
product: 888138
reactant: 888126
fast: false
reversible: false

888138
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000234

888126
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000191

metaid_0000357
type: Reaction
kinetic law: 890289
product: 890277
reactant: 890265
fast: false
reversible: false

890277
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000235

890265
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000171

metaid_0000303
type: Reaction
kinetic law: 887668
product: 887656
reactant: 887644
fast: false
reversible: false

887656
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000184

887644
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000183

metaid_0000115
type: Parameter
constant: true
units: metaid_0000396
value: 0.666

metaid_0000296
type: Reaction
kinetic law: 887401
product: 887389
reactant: 887377
fast: false
reversible: false

887389
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000172

887377
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000173

metaid_0000345
type: Reaction
kinetic law: 889724
modifier: 889712
product: 889700
reactant: 889688
fast: false
reversible: false

889700
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000211

889688
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000210

metaid_0000096
type: Parameter
constant: true
units: dimensionless
value: 2.0

metaid_0000045
type: Parameter
constant: true
units: metaid_0000397
value: 6.66

metaid_0000033
type: Parameter
constant: true
units: metaid_0000398
value: 6.66E-8

metaid_0000159
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000094
type: Parameter
constant: true
units: metaid_0000395
value: 10000.0

metaid_0000138
type: Parameter
constant: true
units: metaid_0000396
value: 0.001

metaid_0000043
type: Parameter
constant: true
units: metaid_0000395
value: 110.0

metaid_0000368
type: Reaction
kinetic law: 890685
product: 890673
product: 890661
reactant: 890649
fast: false
reversible: true

890673
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000244

890661
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

890649
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000202

metaid_0000126
type: Parameter
constant: true
units: metaid_0000395
value: 700.0

metaid_0000031
type: Parameter
constant: true
units: metaid_0000398
value: 0.00933

metaid_0000136
type: Parameter
constant: true
units: metaid_0000396
value: 0.0166

metaid_0000167
type: Species
is version of: REACT 9610
is version of: P01133
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.0
initial amount: NaN
in compartment: metaid_0000166

metaid_0000124
type: Parameter
constant: true
units: metaid_0000396
value: 6.66E-5

metaid_0000335
type: Reaction
product: 889088
fast: false
modifier: 889148
modifier: 889112
reversible: false
modifier: 889100
kinetic law: 889160
modifier: 889136
modifier: 889124

889088
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

metaid_0000192
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000290
type: Reaction
kinetic law: 887136
product: 887124
reactant: 887112
reactant: 887100
fast: false
reversible: true

887124
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000178

887112
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000176

887100
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000172

metaid_0000284
type: Reaction
kinetic law: 886871
product: 886859
reactant: 886847
fast: false
reversible: false

886859
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000171

886847
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000170

metaid_0000333
type: Reaction
kinetic law: 889028
product: 889016
reactant: 889004
fast: false
reversible: false

889016
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000203

889004
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000204

metaid_0000084
type: Parameter
constant: true
units: metaid_0000395
value: 50.0

metaid_0000072
type: Parameter
constant: true
units: metaid_0000398
value: 6.66E-4

metaid_0000021
type: Parameter
constant: true
units: metaid_0000398
value: 4.0E-4

metaid_0000145
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000289
type: Reaction
kinetic law: 887088
product: 887076
reactant: 887064
fast: false
reversible: false

887076
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000174

887064
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000177

metaid_0000356
type: Reaction
kinetic law: 890253
modifier: 890241
product: 890229
reactant: 890217
fast: false
reversible: true

890229
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000233

metaid_0000233
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

890217
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000192

metaid_0000114
type: Parameter
constant: true
units: metaid_0000395
value: 1.0

metaid_0000168
type: Species
is version of: REACT 5828
is version of: P01308
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000166

metaid_0000295
type: Reaction
kinetic law: 887365
product: 887353
reactant: 887341
fast: false
reversible: false

887353
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000216

887341
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000171

metaid_0000344
type: Reaction
kinetic law: 889676
product: 889664
reactant: 889652
fast: false
reversible: false

889664
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000209

889652
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000220

metaid_0000143
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000237
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 200.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000158
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000293
type: Reaction
kinetic law: 887281
product: 887269
reactant: 887257
reactant: 887245
fast: false
reversible: true

887269
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000180

887257
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000179

887245
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000171

metaid_0000105
type: Parameter
constant: true
units: metaid_0000397
value: 33.3

metaid_0000018
type: Parameter
constant: true
units: metaid_0000395
value: 10.0

metaid_0000103
type: Parameter
constant: true
units: metaid_0000396
value: 0.666

metaid_0000298
type: Reaction
kinetic law: 887474
product: 887462
reactant: 887450
fast: false
reversible: false

887462
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000177

887450
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000176

metaid_0000133
type: Parameter
constant: true
units: metaid_0000396
value: 0.0166

metaid_0000121
type: Parameter
constant: true
units: metaid_0000396
value: 0.666

metaid_0000394
type: SBMLUnitsDef
unit: 886616
name: seconds

886616
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 1.0
kind: SECOND

metaid_0000283
type: Reaction
kinetic law: 886835
product: 886823
reactant: 886811
fast: false
reversible: true

886823
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000170

886811
type: SpeciesReference
stoichiometry: 2.0
species: metaid_0000169

metaid_0000131
type: Parameter
constant: true
units: metaid_0000397
value: 133.0

metaid_0000008
type: Parameter
constant: true
units: metaid_0000396
value: 0.4

metaid_0001395
type: SBMLUnitsDef
unit: 886664
unit: 886652
name: per_nM

886664
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE

886652
type: SBMLUnit
exponent: -1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000078
type: Parameter
constant: true
units: metaid_0000395
value: 130.0

metaid_0000163
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000378
type: Reaction
kinetic law: 891178
product: 891166
product: 891154
product: 891142
reactant: 891130
fast: false
reversible: false

891166
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000199

891154
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000196

891142
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000172

891130
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000221

metaid_0000006
type: Parameter
constant: true
units: metaid_0000398
value: 0.033

metaid_0000082
type: Parameter
constant: true
units: metaid_0000396
value: 3.33

metaid_0000366
type: Reaction
kinetic law: 890589
product: 890577
product: 890565
reactant: 890553
fast: false
reversible: true

890577
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000242

890565
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

890553
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000197

metaid_0000142
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000286
type: Reaction
kinetic law: 886968
product: 886955
reactant: 886943
reactant: 886931
fast: false
reversible: true

886955
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000175

886943
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000174

886931
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000171

metaid_0000382
type: Reaction
kinetic law: 891358
product: 891346
product: 891334
reactant: 891322
fast: false
reversible: false

891346
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000198

891334
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

891322
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000246

metaid_0000246
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000038
type: Parameter
constant: true
units: metaid_0000398
value: 0.0066

metaid_0000318
type: Reaction
kinetic law: 888319
modifier: 888307
modifier: 888295
product: 888283
reactant: 888271
fast: false
reversible: false

888283
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000193

888271
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000192

metaid_0000140
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000306
type: Reaction
kinetic law: 887813
product: 887801
reactant: 887789
reactant: 887777
fast: false
reversible: true

887801
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000188

887789
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000187

887777
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000184

metaid_0000017
type: Parameter
constant: true
units: metaid_0000395
value: 100.0

metaid_0000099
type: Parameter
constant: true
units: metaid_0000397
value: 16.6

metaid_0000102
type: Parameter
constant: true
units: metaid_0000395
value: 500.0

metaid_0000068
type: Parameter
constant: true
units: metaid_0000398
value: 0.0133

metaid_0000015
type: Parameter
constant: true
units: metaid_0000395
value: 400.0

metaid_0000387
type: Reaction
fast: false
reactant: 891623
modifier: 891659
product: 891635
kinetic law: 891695
modifier: 891683
product: 891647
modifier: 891671
reversible: false

891623
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000182

891635
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000171

891647
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

metaid_0000153
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000066
type: Parameter
constant: true
units: metaid_0000398
value: 0.002

metaid_0000059
type: Parameter
constant: true
units: metaid_0000398
value: 6.66E-4

metaid_0000385
type: Reaction
kinetic law: 891514
product: 891502
product: 891490
product: 891478
reactant: 891466
fast: false
reversible: false

891502
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000198

891490
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000196

891478
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000172

891466
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000249

metaid_0000151
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000070
type: Parameter
constant: true
units: metaid_0000398
value: 1.0E-5

metaid_0000028
type: Parameter
constant: true
units: metaid_0000398
value: 0.011322

metaid_0000130
type: Parameter
constant: true
units: metaid_0000396
value: 6.66E-5

metaid_0000338
type: Reaction
modifier: 889352
modifier: 889340
modifier: 889364
reactant: 889304
reversible: false
modifier: 889328
kinetic law: 889376
fast: false
product: 889316

metaid_0000251
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.0E-5
initial amount: NaN
in compartment: metaid_0000165

889304
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000226

889316
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000206

metaid_0000089
type: Parameter
constant: true
units: metaid_0000396
value: 0.1

metaid_0000077
type: Parameter
constant: true
units: metaid_0000397
value: 2.0

metaid_0000026
type: Parameter
constant: true
units: metaid_0000395
value: 200.0

metaid_0000370
type: Reaction
kinetic law: 890782
product: 890770
product: 890758
reactant: 890746
fast: false
reversible: true

890770
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000246

890758
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

890746
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000229

metaid_0000162
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000005
type: Parameter
constant: true
units: metaid_0000395
value: 0.58824

metaid_0000319
type: Reaction
kinetic law: 888355
product: 888343
reactant: 888331
fast: false
reversible: false

888343
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000192

888331
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000193

metaid_0000087
type: Parameter
constant: true
units: metaid_0000398
value: 0.0

metaid_0000075
type: Parameter
constant: true
units: metaid_0000396
value: 0.133

metaid_0000049
type: Parameter
constant: true
units: metaid_0000396
value: 33.3

metaid_0000160
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000310
type: Reaction
kinetic law: 887969
product: 887957
reactant: 887945
fast: false
reversible: false

887957
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000216

887945
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000184

metaid_0000003
type: Parameter
constant: false
units: metaid_0000395
value: 3.4

metaid_0000375
type: Reaction
kinetic law: 891022
product: 891010
product: 890998
reactant: 890986
fast: false
reversible: false

891010
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000187

890998
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000172

890986
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000241

metaid_0000037
type: Parameter
constant: true
units: metaid_0000396
value: 0.66

metaid_0000363
type: Reaction
kinetic law: 890445
product: 890433
product: 890421
reactant: 890409
fast: false
reversible: true

890433
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

890421
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000190

890409
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000193

metaid_0000323
type: Reaction
kinetic law: 888547
product: 888535
product: 888523
reactant: 888511
fast: false
reversible: false

888535
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000196

888523
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000192

888511
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000197

metaid_0000060
type: Parameter
constant: true
units: metaid_0000395
value: 1.0

metaid_0000047
type: Parameter
constant: true
units: metaid_0000398
value: 0.00666

metaid_0000373
type: Reaction
kinetic law: 890926
product: 890914
product: 890902
reactant: 890890
fast: false
reversible: true

890914
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000249

890902
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

890890
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000221

ORG:
  orgname: Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University
n:
  given: Nikolay
  family: Borisov

metaid_0000108
type: Parameter
constant: true
units: metaid_0000395
value: 500.0

metaid_0000065
type: Parameter
constant: true
units: metaid_0000395
value: 130.0

metaid_0000384
type: Reaction
kinetic law: 891454
product: 891442
product: 891430
reactant: 891418
fast: false
reversible: false

891442
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000198

891430
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000196

891418
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000248

metaid_0000012
type: Parameter
constant: true
units: metaid_0000398
value: 0.0133

metaid_0000150
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000063
type: Parameter
constant: true
units: metaid_0000395
value: 150.0

metaid_0000056
type: Parameter
constant: true
units: metaid_0000398
value: 6.66E-4

metaid_0000010
type: Parameter
constant: true
units: metaid_0000395
value: 10.0

metaid_0000025
type: Parameter
constant: true
units: metaid_0000398
value: 6.66E-6

metaid_0000351
type: Reaction
kinetic law: 890001
product: 889989
reactant: 889977
fast: false
reversible: false

889989
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000213

889977
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000214

metaid_0000311
type: Reaction
kinetic law: 888005
product: 887993
reactant: 887981
fast: false
reversible: false

887993
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000179

887981
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000185

metaid_0000149
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000054
type: Parameter
constant: true
units: metaid_0000398
value: 0.00666

metaid_0000147
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000372
type: Reaction
kinetic law: 890878
product: 890866
product: 890854
reactant: 890842
fast: false
reversible: true

890866
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000248

890854
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

890842
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000204

metaid_0000360
type: Reaction
kinetic law: 890397
product: 890385
reactant: 890373
fast: false
reversible: false

890385
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000183

890373
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000236

metaid_0000044
type: Parameter
constant: true
units: dimensionless
value: 2.5E-4

metaid_0000032
type: Parameter
constant: true
units: metaid_0000395
value: 124.5

metaid_0000112
type: Parameter
constant: true
units: metaid_0000395
value: 500.0

metaid_0000379
type: Reaction
kinetic law: 891214
product: 891202
reactant: 891190
fast: false
reversible: false

891202
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000198

891190
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000243

metaid_0000137
type: Parameter
constant: true
units: metaid_0000398
value: 0.0133

metaid_0000042
type: Parameter
constant: true
units: metaid_0000396
value: 6.6

metaid_0000367
type: Reaction
kinetic law: 890637
product: 890625
product: 890613
reactant: 890601
fast: false
reversible: true

890625
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000243

890613
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

890601
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000200

metaid_0000125
type: Parameter
constant: true
units: metaid_0000396
value: 0.04

metaid_0000030
type: Parameter
constant: true
units: metaid_0000396
value: 1.66

metaid_0000156
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000135
type: Parameter
constant: true
units: metaid_0000395
value: 266.0

metaid_0000053
type: Parameter
constant: true
units: metaid_0000398
value: 6.66E-4

metaid_0000238
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000146
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000051
type: Parameter
constant: true
units: dimensionless
value: 0.05

metaid_0000332
type: Reaction
kinetic law: 888992
modifier: 888980
modifier: 888968
product: 888956
reactant: 888944
fast: false
reversible: false

888956
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000204

888944
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000203

metaid_0000020
type: Parameter
constant: true
units: metaid_0000395
value: 400.0

metaid_0000222
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: metaid_0000165

metaid_0000355
type: Reaction
kinetic law: 890205
modifier: 890193
product: 890181
reactant: 890169
fast: false
reversible: true

890181
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000232

890169
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000199

metaid_0000113
type: Parameter
constant: true
units: metaid_0000397
value: 16.66

metaid_0000294
type: Reaction
kinetic law: 887329
product: 887317
reactant: 887305
reactant: 887293
fast: false
reversible: true

887317
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000182

887305
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

887293
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000171

metaid_0000326
type: Reaction
kinetic law: 888691
product: 888679
reactant: 888667
fast: false
reversible: false

888679
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000199

888667
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000200

metaid_0000157
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000292
type: Reaction
kinetic law: 887233
product: 887221
product: 887209
reactant: 887197
fast: false
reversible: true

887221
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000177

887209
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000172

887197
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000219

metaid_0000041
type: Parameter
constant: true
units: metaid_0000395
value: 143.3

metaid_0000389
type: Reaction
kinetic law: 891839
modifier: 891827
product: 891815
product: 891803
reactant: 891791
fast: false
reversible: false

891815
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

891803
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000171

891791
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000182

metaid_0000329
type: Reaction
kinetic law: 888835
product: 888823
reactant: 888811
reactant: 888799
fast: false
reversible: true

888823
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000229

888811
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000200

888799
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

metaid_0000100
type: Parameter
constant: true
units: metaid_0000395
value: 675.299

metaid_0000390
type: Reaction
kinetic law: 891899
modifier: 891887
product: 891875
product: 891863
reactant: 891851
fast: false
reversible: false

891875
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000184

891863
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

891851
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000186

metaid_0000282
type: Reaction
kinetic law: 886798
product: 886786
reactant: 886774
reactant: 886762
fast: false
reversible: true

886786
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000169

886774
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000167

886762
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000222

metaid_0000354
type: Reaction
kinetic law: 890157
modifier: 890145
product: 890133
reactant: 890121
fast: false
reversible: true

890133
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000231

890121
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000172

metaid_0000314
type: Reaction
kinetic law: 888114
product: 888102
reactant: 888090
fast: false
reversible: false

888102
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000190

888090
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000189

metaid_0000342
type: Reaction
fast: false
modifier: 889580
product: 889544
modifier: 889556
reversible: false
kinetic law: 889592
modifier: 889568
reactant: 889532

889544
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000207

889532
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000217

metaid_0000302
type: Reaction
kinetic law: 887632
product: 887620
reactant: 887608
reactant: 887595
fast: false
reversible: true

887620
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000183

887608
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000224

887595
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000168

metaid_0000093
type: Parameter
constant: true
units: metaid_0000396
value: 0.666

metaid_0000377
type: Reaction
kinetic law: 891118
product: 891106
product: 891094
reactant: 891082
fast: false
reversible: false

891106
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000199

891094
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000196

891082
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000204

metaid_0000081
type: Parameter
constant: true
units: metaid_0000396
value: 4.66

metaid_0000141
type: Parameter
constant: false
units: metaid_0000396
value: NaN

metaid_0000307
type: Reaction
kinetic law: 887849
product: 887837
reactant: 887825
fast: false
reversible: false

887837
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000189

887825
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000188

metaid_0000119
type: Parameter
constant: true
units: metaid_0000396
value: 0.666

metaid_0000349
type: Reaction
kinetic law: 889916
product: 889904
reactant: 889892
reactant: 889880
fast: false
reversible: true

889904
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000225

889892
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000212

889880
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

metaid_0000381
type: Reaction
kinetic law: 891310
product: 891298
product: 891286
reactant: 891274
fast: false
reversible: false

891298
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000198

891286
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000172

891274
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000245

metaid_0000317
type: Reaction
kinetic law: 888258
product: 888246
reactant: 888234
reactant: 888222
fast: false
reversible: true

888246
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000192

888234
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000205

888222
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000187

metaid_0000305
type: Reaction
kinetic law: 887765
product: 887753
reactant: 887741
reactant: 887729
fast: false
reversible: true

887753
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000186

887741
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000184

887729
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000181

W3 CDTF: Thu Jul 09 12:00:31 BST 2009

W3 CDTF: Fri Mar 09 11:44:02 GMT 2012