BIOMD0000000201
type: SBMLModel
species: metaid_0000100
parameter: metaid_0000011
reaction: metaid_0110172
reaction: metaid_0000169
species: metaid_0000047
reaction: metaid_0000160
parameter: metaid_0000090
rule: metaid_0000123
reaction: metaid_0000176
parameter: metaid_0000036
rule: metaid_0000134
species: metaid_0000119
species: metaid_0000101
reaction: metaid_0000172
parameter: metaid_0000048
parameter: metaid_0000039
reaction: metaid_0000168
reaction: metaid_0000167
parameter: metaid_0000028
species: metaid_0000112
units def: metaid_0000007
reaction: metaid_0000157
is: MODEL6415057828
parameter: metaid_0000034
has version: GO:0007219
units def: metaid_0010003
parameter: metaid_0000050
parameter: metaid_0000076
volume units: metaid_0000005
parameter: metaid_0000057
species: metaid_0000117
parameter: metaid_0000030
parameter: metaid_0000094
parameter: metaid_0000085
parameter: metaid_0000137
parameter: metaid_0000053
parameter: metaid_0000088
parameter: metaid_0000079
occurs in: http://identifiers.org/taxonomy/32524
parameter: metaid_0000027
has version: ko04330
parameter: metaid_0000143
parameter: metaid_0000139
reaction: metaid_0000155
parameter: metaid_0000042
parameter: metaid_0000016
parameter: metaid_0000033
species: metaid_0000107
species: metaid_0000110
has version: GO:0016055
notes: This is a model of the coupled Natch, Wnt and FGF modules as described in: A. Goldbeter and O. Pourquié , Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways. J Theor Biol. 2008 Jun 7;252(3):574-85, pubmed ID: 18308339 To uncouple the modules remove the reaction MAx_trans_Xa and set vsFK=vsF . The SBML version of the model was converted from the CellML version by Catherine Lloyd for the CellML repository . To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
parameter: metaid_0000018
parameter: metaid_0000022
substance units: metaid_0010003
species: metaid_0000099
parameter: metaid_0000081
parameter: metaid_0000136
species: metaid_0000104
parameter: metaid_0000087
parameter: metaid_0000142
reaction: metaid_0000183
parameter: metaid_0000041
parameter: metaid_0000015
species: metaid_0000111
parameter: metaid_0000067
reaction: metaid_0000180
length unit: length
units def: metaid_0000005
reaction: metaid_0000163
parameter: metaid_0000093
species: metaid_0000075
parameter: metaid_0000021
species: metaid_0000105
has version: REACT 299.2
parameter: metaid_0000010
is part of: GO:0001756
parameter: metaid_0000080
has version: ko04010
reaction: metaid_0000175

metaid_0000100
type: Species
initial concentration: 0.1
is version of: CHEBI:33699
in compartment: metaid_0000095
name: Lunatic fringe mRNA
has only substance units: false
is: SBO:0000250
encodes: Q8NES3
initial amount: NaN
encodes: IPR017374
constant: false
boundary condition: false

metaid_0000095
type: Compartment
is: GO:0005829
constant: true
units: litre
size: 1.0
spatial dimensions: 3.0

metaid_0000011
type: Parameter
is: SBO:0000324
constant: true
units: metaid_0000006
value: 2.82
name: vdN

metaid_0000006
type: SBMLUnitsDef
unit: 389838
unit: 389826
unit: 389813
name: flux

389838
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND

389826
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE

389813
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0110172
type: Reaction
kinetic law: 390500
modifier: 390488
product: 390476
is version of: GO:0009299
is: SBO:0000183
fast: false
reversible: false

metaid_0000103
type: Species
has only substance units: false
in compartment: metaid_0000095
initial concentration: 0.001
boundary condition: false
constant: false
name: nuclear beta-catenin
is homolog to: P35222
initial amount: NaN
is version of: IPR013284
is: SBO:0000252

390476
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000107

metaid_0000107
type: Species
encodes: Q9Y2T1
initial concentration: 0.1
is version of: CHEBI:33699
in compartment: metaid_0000095
boundary condition: false
initial amount: NaN
is homolog to: ENSG00000168646
is: SBO:0000250
constant: false
name: Axin2 mRNA
has only substance units: false

metaid_0000169
type: Reaction
kinetic law: 390368
product: 390356
reactant: 390344
is version of: GO:0006470
is: SBO:0000330
fast: false
reversible: false

390356
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000106

metaid_0000106
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.1
is: SBO:0000252
in compartment: metaid_0000095
name: beta-catenin
initial amount: NaN
is version of: IPR013284

390344
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000102

metaid_0000102
type: Species
is homolog to: P35222
has only substance units: false
is: SBO:0000252
constant: false
is version of: C00562
in compartment: metaid_0000095
initial amount: NaN
name: phosph. beta-catenin
boundary condition: false
is version of: IPR013284
initial concentration: 0.1

metaid_0000047
type: Species
is homolog to: P49841
has only substance units: false
initial concentration: 3.0
is: SBO:0000252
in compartment: metaid_0000095
initial amount: NaN
name: Kt
boundary condition: false
constant: true

metaid_0000160
type: Reaction
kinetic law: 390043
reactant: 390031
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: false

390031
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000099

metaid_0000099
type: Species
initial concentration: 0.0
name: nuclear NicD
in compartment: metaid_0000095
boundary condition: false
is: SBO:0000252
has only substance units: false
initial amount: NaN
constant: false
is part of: IPR008297

metaid_0000090
type: Parameter
is: SBO:0000191
constant: true
units: dimensionless
value: 2.0
name: j

metaid_0000176
type: Reaction
is version of: GO:0032856
kinetic law: 390670
modifier: 390646
fast: false
product: 390633
is version of: REACT 2010.5
reversible: false
modifier: 390658

metaid_0000113
type: Species
boundary condition: true
constant: false
name: inactive Ras
in compartment: metaid_0000095
is: SBO:0000252
initial concentration: NaN
has only substance units: false
has version: IPR001806
initial amount: NaN
has version: CHEBI:17552

390633
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000108

metaid_0000108
type: Species
has version: IPR001806
is: SBO:0000252
initial concentration: 0.5
has version: CHEBI:15996
has only substance units: false
boundary condition: false
initial amount: NaN
in compartment: metaid_0000095
constant: false
name: active Ras

metaid_0000075
type: Species
boundary condition: false
in compartment: metaid_0000095
name: Fgf
is: SBO:0000252
is version of: IPR017338
initial concentration: 1.0
initial amount: NaN
constant: true
has only substance units: false

metaid_0000036
type: Parameter
constant: true
units: metaid_0000007
value: 0.48
name: Kmd

metaid_0000007
type: SBMLUnitsDef
unit: 389862
unit: 389850
name: nanomolar

389862
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE

389850
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000119
type: Species
initial concentration: 2.0
is: SBO:0000252
is homolog to: O14640
in compartment: metaid_0000095
constant: false
name: Dsh protein
boundary condition: false
is version of: IPR003351
initial amount: NaN
has only substance units: false

metaid_0000101
type: Species
boundary condition: false
in compartment: metaid_0000095
has only substance units: false
initial amount: NaN
is: SBO:0000252
is version of: IPR017374
constant: false
is homolog to: Q8NES3
name: Lunatic Fringe protein
initial concentration: 0.001

metaid_0000172
type: Reaction
kinetic law: 390464
modifier: 390452
product: 390440
is version of: GO:0009299
is: SBO:0000183
fast: false
reversible: false

390440
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000107

metaid_0000048
type: Parameter
is: SBO:0000338
constant: true
units: metaid_0000004
value: 0.1
name: d1

metaid_0000004
type: SBMLUnitsDef
unit: 389765
name: first_order_rate_constant

389765
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND

metaid_0000039
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.5
name: vMXa

metaid_0000168
type: Reaction
is version of: REACT 11065.1
is: SBO:0000216
modifier: 390308
fast: false
reversible: false
product: 390284
reactant: 390272
kinetic law: 390332
modifier: 390296
is version of: GO:0006468
modifier: 390320

390284
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000102

390272
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000106

metaid_0000120
type: Species
constant: false
has only substance units: false
has part: Q9Y2T1
is: SBO:0000297
in compartment: metaid_0000095
name: Axin2/Gsk3 destruction complex
boundary condition: true
initial amount: NaN
has part: P49841
initial concentration: NaN

metaid_0000167
type: Reaction
kinetic law: 390260
reactant: 390248
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: false

390248
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000106

metaid_0000028
type: Parameter
is: SBO:0000022
constant: true
units: metaid_0000004
value: 0.0
name: kd1

metaid_0000112
type: Species
constant: false
initial concentration: 0.1
is: SBO:0000252
boundary condition: false
is homolog to: Q16828
initial amount: NaN
has only substance units: false
name: Dusp6 protein
in compartment: metaid_0000095

metaid_0000157
type: Reaction
is: SBO:0000178
is version of: GO:0007220
kinetic law: 389959
product: 389934
reactant: 389922
modifier: 389946
name: Notch_activation
fast: false
reversible: false
is version of: REACT 691.2

389934
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000098

metaid_0000098
type: Species
in compartment: metaid_0000095
is: SBO:0000252
has only substance units: false
name: cytosolic NicD
initial amount: NaN
constant: false
is part of: IPR008297
boundary condition: false
initial concentration: 0.2

389922
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000097

metaid_0000097
type: Species
in compartment: metaid_0000095
is version of: IPR008297
has only substance units: false
name: Notch protein
constant: false
boundary condition: false
is: SBO:0000252
initial concentration: 0.5
is homolog to: P46531
initial amount: NaN

metaid_0000034
type: Parameter
constant: true
units: metaid_0000007
value: 0.7
name: KaB

metaid_0010003
type: SBMLUnitsDef
unit: 389741
name: nanomole

389741
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000050
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.28
name: K1

metaid_0000076
type: Parameter
is: SBO:0000191
constant: true
units: metaid_0000007
value: 0.5
name: KaFgf

metaid_0000057
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 2.0
name: vdDusp

metaid_0000117
type: Species
initial amount: NaN
is: SBO:0000252
in compartment: metaid_0000095
is version of: IPR008349
boundary condition: false
name: ERK total
constant: false
initial concentration: 2.0
has only substance units: false

metaid_0000030
type: Parameter
is: SBO:0000022
constant: true
units: metaid_0000004
value: 7.062
name: kd2

metaid_0000094
type: Parameter
is: SBO:0000381
constant: true
units: dimensionless
value: 0.3
name: eta

metaid_0000085
type: Parameter
is: SBO:0000191
constant: true
units: metaid_0000007
value: 0.5
name: KaMDusp

metaid_0000137
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.5
name: VMdMDusp

metaid_0000053
type: Parameter
is: SBO:0000032
constant: true
units: metaid_0000004
value: 1.5
name: kt4

metaid_0000088
type: Parameter
is: SBO:0000191
constant: true
units: dimensionless
value: 2.0
name: r

metaid_0000079
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.05
name: KdErk

metaid_0000027
type: Parameter
is: SBO:0000022
constant: true
units: metaid_0000004
value: 0.3
name: ksF

metaid_0000143
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 1.6
name: VMaX

metaid_0000139
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 1.0
name: VMP

metaid_0000155
type: Reaction
kinetic law: 389886
product: 389874
is version of: GO:0010467
fast: false
reversible: false
name: Notch_synthesis

389874
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000097

metaid_0000042
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.63
name: KdAx

metaid_0000016
type: Parameter
is: SBO:0000032
constant: true
units: metaid_0000004
value: 0.1
name: kt2

metaid_0000033
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.8
name: vmd

metaid_0000110
type: Species
initial amount: NaN
is version of: IPR006715
initial concentration: 0.1
boundary condition: false
constant: false
has only substance units: false
is: SBO:0000252
in compartment: metaid_0000095
name: active TF X

metaid_0000018
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.1
name: VdNan

metaid_0000022
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 3.0
name: vsF

metaid_0000081
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.05
name: KaX

metaid_0000136
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.9
name: VMsMDusp

metaid_0000104
type: Species
is: SBO:0000252
name: Axin2 protein
is homolog to: Q9Y2T1
has only substance units: false
boundary condition: false
in compartment: metaid_0000095
initial concentration: 0.1
constant: false
initial amount: NaN

metaid_0000087
type: Parameter
is: SBO:0000190
constant: true
units: dimensionless
value: 2.0
name: q

metaid_0000142
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 3.3
name: VMaErk

metaid_0000183
type: Reaction
kinetic law: 390937
reactant: 390925
is version of: GO:0006402
is: SBO:0000179
fast: false
reversible: false

390925
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000111

metaid_0000111
type: Species
name: Dusp6 mRNA
is: SBO:0000250
initial amount: NaN
has only substance units: false
in compartment: metaid_0000095
encodes: Q16828
boundary condition: false
is homolog to: ENSG00000139318
constant: false
initial concentration: 0.1

metaid_0000041
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.6
name: vdAx

metaid_0000015
type: Parameter
is: SBO:0000022
constant: true
units: metaid_0000004
value: 0.1
name: kt1

metaid_0000067
type: Parameter
is: SBO:0000022
constant: true
units: metaid_0000004
value: 1.35
name: kcDusp

metaid_0000180
type: Reaction
modifier: 390816
product: 390804
kinetic law: 390852
reversible: false
is version of: GO:0051091
fast: false
modifier: 390828
modifier: 390840

metaid_0000109
type: Species
has only substance units: false
is version of: IPR008349
initial amount: NaN
in compartment: metaid_0000095
boundary condition: false
initial concentration: 0.2
constant: false
is: SBO:0000252
name: active ERK

390804
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000110

metaid_0000115
type: Species
is version of: IPR006715
has only substance units: false
is: SBO:0000252
boundary condition: true
initial amount: NaN
in compartment: metaid_0000095
constant: false
initial concentration: NaN
name: inactive TF X

metaid_0000005
type: SBMLUnitsDef
unit: 389801
unit: 389789
unit: 389777
name: second_order_rate_constant

389801
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND

389789
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE

389777
type: SBMLUnit
exponent: -1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000163
type: Reaction
kinetic law: 390140
modifier: 390128
product: 390116
is version of: GO:0006412
is: SBO:0000184
fast: false
reversible: false

390116
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000101

metaid_0000093
type: Parameter
is: SBO:0000381
constant: true
units: dimensionless
value: 1.5
name: theta

metaid_0000021
type: Parameter
is: SBO:0000186
constant: false
units: metaid_0000006
value: NaN
name: vsFK

metaid_0000105
type: Species
initial concentration: 3.0
in compartment: metaid_0000095
has only substance units: false
constant: false
boundary condition: false
initial amount: NaN
is homolog to: P49841
is: SBO:0000252
name: Gsk3

metaid_0000010
type: Parameter
is: SBO:0000048
constant: true
units: metaid_0000006
value: 0.23
name: vsN

metaid_0000080
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.05
name: KaErk

metaid_0000175
type: Reaction
kinetic law: 390621
reactant: 390609
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: false

390609
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000104

metaid_0000166
type: Reaction
kinetic law: 390236
product: 390224
is version of: GO:0010467
fast: false
reversible: false

390224
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000106

metaid_0000116
type: Species
initial amount: NaN
initial concentration: 2.0
in compartment: metaid_0000095
is version of: IPR001806
boundary condition: false
constant: false
name: Ras total
is: SBO:0000252
has only substance units: false

metaid_0000013
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.001
name: KdNa

metaid_0000009
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 1.4
name: KdN

metaid_0000058
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.5
name: KdDusp

metaid_0000171
type: Reaction
kinetic law: 390428
reactant: 390416
is version of: GO:0030163
is version of: REACT 11063.1
is: SBO:0000179
fast: false
reversible: false

390416
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000102

metaid_0000162
type: Reaction
kinetic law: 390104
reactant: 390092
is version of: GO:0006402
is: SBO:0000179
fast: false
reversible: false

390092
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000100

metaid_0000092
type: Parameter
is: SBO:0000381
constant: true
units: dimensionless
value: 0.3
name: epsilon

metaid_0000178
type: Reaction
fast: false
modifier: 390719
is version of: REACT 1482.4
product: 390707
modifier: 390744
reversible: false
kinetic law: 390756
modifier: 390731

metaid_0000114
type: Species
in compartment: metaid_0000095
is: SBO:0000252
is version of: IPR008349
has only substance units: false
name: inactive ERK
initial amount: NaN
initial concentration: NaN
boundary condition: true
constant: false

390707
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000109

metaid_0000038
type: Parameter
is: SBO:0000190
constant: true
units: dimensionless
value: 2.0
name: m

metaid_0000003
type: SBMLUnitsDef
unit: 389753
name: minute

389753
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 60.0
kind: SECOND

metaid_0000174
type: Reaction
kinetic law: 390597
modifier: 390584
product: 390572
is version of: GO:0006412
is: SBO:0000184
fast: false
reversible: false

390572
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000104

metaid_0000179
type: Reaction
kinetic law: 390792
modifier: 390780
reactant: 390768
is version of: REACT 12436.1
fast: false
reversible: false

390768
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000109

metaid_0100172
type: Reaction
kinetic law: 390536
modifier: 390524
product: 390512
is version of: GO:0009299
is: SBO:0000183
fast: false
reversible: false

390512
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000107

metaid_0000056
type: Parameter
is: SBO:0000022
constant: true
units: metaid_0000004
value: 0.5
name: ksDusp

metaid_0000159
type: Reaction
reactant: 389995
kinetic law: 390019
is version of: REACT 2155.3
reversible: true
product: 390007
is: SBO:0000185
fast: false
is version of: GO:0006913

389995
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000098

390007
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000099

metaid_0000037
type: Parameter
is: SBO:0000190
constant: true
units: dimensionless
value: 2.0
name: n

metaid_0000084
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.05
name: KdX

metaid_0000052
type: Parameter
is: SBO:0000022
constant: true
units: metaid_0000004
value: 0.7
name: kt3

metaid_0000078
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.1
name: KdRas

metaid_0000026
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.39
name: vdF

metaid_0000170
type: Reaction
kinetic law: 390404
product: 390392
reactant: 390380
is version of: GO:0006913
is: SBO:0000185
fast: false
reversible: true

390392
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000106

390380
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000103

metaid_0000032
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 1.64
name: vMB

metaid_0000049
type: Parameter
is: SBO:0000023
constant: true
units: metaid_0000005
value: 1.8
name: a1

metaid_0000029
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.087
name: vsB

metaid_0000158
type: Reaction
kinetic law: 389983
reactant: 389971
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: false
name: Na_degradation

389971
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000098

metaid_0000035
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.05
name: KaXa

metaid_0000083
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.5
name: KID

metaid_0000051
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.03
name: K2

metaid_0000086
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.5
name: KdMDusp

metaid_0000077
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.103
name: KaRas

metaid_0000025
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.37
name: KdF

metaid_0000024
type: Parameter
constant: true
units: metaid_0000007
value: 0.05
name: KA

metaid_0000141
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.41
name: VMdRas

metaid_0000040
type: Parameter
is: SBO:0000022
constant: true
units: metaid_0000004
value: 0.02
name: ksAx

metaid_0000014
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.01
name: VdNa

metaid_0000031
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.06
name: v0

metaid_0000182
type: Reaction
kinetic law: 390913
modifier: 390901
product: 390889
is version of: GO:0009299
is: SBO:0000183
fast: false
reversible: false

390889
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000111

ORG:
  orgname: EMBL-EBI
n:
  given: Lukas
  family: Endler

metaid_0000138
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 5.08
name: VMK

metaid_0000020
type: Parameter
constant: true
units: metaid_0000007
value: 2.5
name: KIG1

metaid_0000089
type: Parameter
is: SBO:0000022
constant: true
units: metaid_0000004
value: 3.45
name: kc

metaid_0000144
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.5
name: VMdX

metaid_0000185
type: Reaction
kinetic law: 390997
reactant: 390985
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: false

390985
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000112

metaid_0000156
type: Reaction
kinetic law: 389910
reactant: 389898
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: false
name: N_degradation

389898
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000097

metaid_0000017
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.001
name: KdNan

metaid_0000165
type: Reaction
reactant: 390176
fast: false
kinetic law: 390212
product: 390200
is: SBO:0000180
reversible: true
product: 390188
is version of: GO:0043241

390176
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000120

390200
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000105

390188
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000104

metaid_0000019
type: Parameter
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.768
name: KdMF

metaid_0000023
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 1.92
name: vmF

metaid_0000140
type: Parameter
is: SBO:0000186
constant: true
units: metaid_0000006
value: 4.968
name: VMaRas

metaid_0000161
type: Reaction
kinetic law: 390080
modifier: 390068
product: 390055
is version of: GO:0009299
is: SBO:0000183
fast: false
reversible: false

390055
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000100

metaid_0000091
type: Parameter
is: SBO:0000191
constant: true
units: dimensionless
value: 2.0
name: p

metaid_0000082
type: Parameter
is: SBO:0000191
constant: true
units: metaid_0000007
value: 0.5
name: KIF

metaid_0000177
type: Reaction
kinetic law: 390694
reactant: 390682
is version of: GO:0034261
fast: false
reversible: false

390682
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000108

metaid_0000184
type: Reaction
kinetic law: 390973
modifier: 390961
product: 390949
is version of: GO:0006412
is: SBO:0000184
fast: false
reversible: false

390949
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000112

metaid_0000118
type: Species
is: SBO:0000252
initial concentration: 2.0
in compartment: metaid_0000095
name: X total
is version of: IPR006715
constant: false
has only substance units: false
boundary condition: false
initial amount: NaN

metaid_0000181
type: Reaction
kinetic law: 390877
reactant: 390865
is version of: GO:0043433
fast: false
reversible: false

390865
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000110

metaid_0000173
type: Reaction
kinetic law: 390560
reactant: 390548
is version of: GO:0006402
is: SBO:0000179
fast: false
reversible: false

390548
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000107

metaid_0000164
type: Reaction
kinetic law: 390164
reactant: 390152
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: false

390152
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000101

ORG:
  orgname: University of Auckland
n:
  given: Catherine
  family: Lloyd

W3 CDTF: Wed Jun 05 18:17:15 BST 2013

W3 CDTF: Fri Nov 07 15:03:43 GMT 2008