BIOMD0000000181
type: SBMLModel
reaction: metaid_0000046
is part of: GO:0000278
time units: metaid_0000055
parameter: metaid_0000006
parameter: metaid_0000014
parameter: metaid_0000024
reaction: metaid_0000037
parameter: metaid_0000015
notes: The model reproduces the time profile of species depicted in Figure 12a and 12 b. The authors communicated to the curator that there is a typo in the paper, the values of kd1 and kd2 are reversed. Model successfully reproduced using MathSBML.
name: Sriram2007_CellCycle
is part of: sce04111
curated: true
parameter: metaid_0000004
is: MODEL8610478473
reaction: metaid_0000052
species: metaid_0000034
reaction: metaid_0000048
reaction: metaid_0000038
species: metaid_0000031
compartment: metaid_0000028
parameter: metaid_0000010
units def: metaid_0000056
parameter: metaid_0000020
parameter: metaid_0000008
parameter: metaid_0000026
parameter: metaid_0000011
reaction: metaid_0000047
parameter: metaid_0000017
units def: metaid_0000054
parameter: metaid_0000007
units def: metaid_0000058
parameter: metaid_0000025
parameter: metaid_0000005
reaction: metaid_0000042
creator:
  ORG:
    orgname: California Institute of Technology
  n:
    given: Harish
    family: Dharuri
length unit: length
is homolog to: REACT 152
reaction: metaid_0000044
reaction: metaid_0000040
parameter: metaid_0000012
parameter: metaid_0000022
species: metaid_0000033
modified:
  W3 CDTF: Wed May 16 11:02:23 BST 2012
parameter: metaid_0000018
reaction: metaid_0000049
parameter: metaid_0000021
created:
  W3 CDTF: Tue Aug 12 22:04:02 BST 2008
units def: metaid_0000055
parameter: metaid_0000009
parameter: metaid_0000019
parameter: metaid_0000027
is described by: http://identifiers.org/pubmed/18203579
volume units: metaid_0000020
substance units: metaid_0000054
parameter: metaid_0000016
occurs in: http://identifiers.org/taxonomy/33154
species: metaid_0000035
parameter: metaid_0000003
parameter: metaid_0000013
reaction: metaid_0000043
reaction: metaid_0000053
reaction: metaid_0000050
reaction: metaid_0000045
species: metaid_0000032
reaction: metaid_0000041
reaction: metaid_0000051
area units: metaid_0000005
parameter: metaid_0000023
reaction: metaid_0000039
species: metaid_0000030
units def: metaid_0000057
reaction: metaid_0000036

metaid_0000046
type: Reaction
kinetic law: 973979
modifier: 973967
product: 973955
is version of: GO:0045727
fast: false
reversible: false

metaid_0000035
type: Species
is version of: P38634
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000028
name: C3

metaid_0000028
type: Compartment
constant: true
size: 1.0
spatial dimensions: 3.0

973955
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000032

metaid_0000032
type: Species
is version of: P08153
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.0
initial amount: NaN
in compartment: metaid_0000028
name: T3

metaid_0000055
type: SBMLUnitsDef
unit: 973565
name: minutes

973565
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 60.0
kind: SECOND

metaid_0000006
type: Parameter
constant: true
units: metaid_0000057
value: 5.0

metaid_0000057
type: SBMLUnitsDef
unit: 973625
unit: 973613
name: nM

973625
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE

973613
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000014
type: Parameter
constant: true
units: metaid_0000056
value: 0.2

metaid_0000056
type: SBMLUnitsDef
unit: 973601
unit: 973589
unit: 973577
name: nM_min_1

973601
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND

973589
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE

973577
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000024
type: Parameter
constant: true
units: metaid_0000058
value: 0.16

metaid_0000058
type: SBMLUnitsDef
unit: 973637
name: min_1

973637
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND

metaid_0000037
type: Reaction
kinetic law: 973698
modifier: 973686
product: 973674
is version of: GO:0045727
fast: false
reversible: false

973674
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030

metaid_0000030
type: Species
is version of: P25302
constant: false
boundary condition: false
has only substance units: false
initial concentration: 6.0
initial amount: NaN
in compartment: metaid_0000028
name: T1

metaid_0000015
type: Parameter
constant: true
units: metaid_0000056
value: 3.0

metaid_0000004
type: Parameter
constant: true
units: metaid_0000056
value: 6.0

metaid_0000052
type: Reaction
kinetic law: 974196
modifier: 974184
modifier: 974172
product: 974160
is version of: GO:0045727
fast: false
reversible: false

metaid_0000033
type: Species
has only substance units: false
has part: P20437
in compartment: metaid_0000028
boundary condition: false
initial concentration: 0.0
initial amount: NaN
has part: P00546
name: C1
constant: false

974160
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000035

metaid_0000034
type: Species
has only substance units: false
in compartment: metaid_0000028
initial amount: NaN
name: C2
constant: false
has part: P24868
boundary condition: false
initial concentration: 0.0
has part: P00546

metaid_0000048
type: Reaction
kinetic law: 974052
modifier: 974039
modifier: 974027
product: 974015
is version of: GO:0045727
fast: false
reversible: false

974015
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000033

metaid_0000038
type: Reaction
kinetic law: 973736
modifier: 973723
product: 973710
is version of: GO:0045727
fast: false
reversible: false

973710
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030

metaid_0000031
type: Species
is version of: P11746
constant: false
boundary condition: false
has only substance units: false
initial concentration: 5.0
initial amount: NaN
in compartment: metaid_0000028
name: T2

metaid_0000010
type: Parameter
constant: true
units: metaid_0000056
value: 1.052

metaid_0000020
type: Parameter
constant: true
units: metaid_0000057
value: 10.0

metaid_0000008
type: Parameter
constant: true
units: metaid_0000058
value: 0.8

metaid_0000026
type: Parameter
constant: true
units: metaid_0000057
value: 10.0

metaid_0000011
type: Parameter
constant: true
units: metaid_0000057
value: 5.0

metaid_0000047
type: Reaction
kinetic law: 974003
reactant: 973991
is version of: GO:0044257
fast: false
reversible: false

973991
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000032

metaid_0000017
type: Parameter
constant: true
units: metaid_0000058
value: 0.6

metaid_0000054
type: SBMLUnitsDef
unit: 973553
name: nano mole

973553
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000007
type: Parameter
constant: true
units: metaid_0000058
value: 0.2

metaid_0000025
type: Parameter
constant: true
units: metaid_0000056
value: 15.0

metaid_0000005
type: Parameter
constant: true
units: dimensionless
value: 2.0

metaid_0000042
type: Reaction
kinetic law: 973858
modifier: 973846
product: 973834
is version of: GO:0045727
fast: false
reversible: false

973834
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

metaid_0000044
type: Reaction
kinetic law: 973906
product: 973894
is version of: GO:0045727
fast: false
reversible: false

973894
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000032

metaid_0000040
type: Reaction
kinetic law: 973786
product: 973774
is version of: GO:0045727
fast: false
reversible: false

973774
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

metaid_0000012
type: Parameter
constant: true
units: metaid_0000058
value: 0.22

metaid_0000022
type: Parameter
constant: true
units: metaid_0000056
value: 15.0

metaid_0000018
type: Parameter
constant: true
units: metaid_0000058
value: 0.8

metaid_0000049
type: Reaction
kinetic law: 974076
reactant: 974064
is version of: GO:0044257
fast: false
reversible: false

974064
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000033

metaid_0000021
type: Parameter
constant: true
units: metaid_0000058
value: 0.16

metaid_0000009
type: Parameter
constant: true
units: metaid_0000056
value: 0.5

metaid_0000019
type: Parameter
constant: true
units: metaid_0000056
value: 15.0

metaid_0000027
type: Parameter
constant: true
units: metaid_0000058
value: 0.16

metaid_0000016
type: Parameter
constant: true
units: metaid_0000057
value: 5.0

metaid_0000003
type: Parameter
constant: true
units: metaid_0000056
value: 0.9

metaid_0000013
type: Parameter
constant: true
units: metaid_0000058
value: 0.9

metaid_0000043
type: Reaction
kinetic law: 973882
reactant: 973870
is version of: GO:0044257
fast: false
reversible: false

973870
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

metaid_0000053
type: Reaction
kinetic law: 974220
reactant: 974208
is version of: GO:0044257
fast: false
reversible: false

974208
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000035

metaid_0000050
type: Reaction
kinetic law: 974124
modifier: 974112
modifier: 974100
product: 974088
is version of: GO:0045727
fast: false
reversible: false

974088
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000034

metaid_0000045
type: Reaction
kinetic law: 973943
modifier: 973930
product: 973918
is version of: GO:0045727
fast: false
reversible: false

973918
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000032

metaid_0000041
type: Reaction
kinetic law: 973822
modifier: 973810
product: 973798
is version of: GO:0045727
fast: false
reversible: false

973798
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

metaid_0000051
type: Reaction
kinetic law: 974148
reactant: 974136
is version of: GO:0044257
fast: false
reversible: false

974136
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000034

metaid_0000023
type: Parameter
constant: true
units: metaid_0000057
value: 10.0

metaid_0000039
type: Reaction
kinetic law: 973761
reactant: 973749
is version of: GO:0044257
fast: false
reversible: false

973749
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030

metaid_0000036
type: Reaction
kinetic law: 973661
product: 973649
is version of: GO:0045727
fast: false
reversible: false

973649
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030