IL6-gp80-gp130-JAK dimer-SHP2 dissociation
IL6-gp80-gp130-JAK-STAT3Cast complex formation
IL6-gp80-gp130-JAK SHP2 Grb2 dissociation
The model reproduces Fig 2 , Fig3A and Fig 3B of the paper. The ODE for x1(gp180) and x3 (gp 130) is wrong and the authors have communicated to the curator that the species ought to have a constant value. There are a few other differences from the paper and these were made in consultation with the authors. Model was successfully tested on MathSBML. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
IL6-gp80-gp130-JAK-SOCS2-STAT3C complex formation
IL6-gp80-gp130-JAK -SHP2 complex formation
IL6-gp80-gp130-JAK -SHP2 dimer dissociation
IL6-gp80-gp130-JAK-STAT3C-SOCS3-SHP2 dissociation
IL6-gp80-gp130-JAK -STAT3C complex formation
IL6-gp80-gp130-JAK -SOCS3 complex formation
IL6-gp80-gp130-JAK STAT3Cast complex formation
IL6-gp80-gp130-JAK-SHP2-Grb2-SOS dissociation
IL6-gp80-gp130-JAK dimer phosphorylation