BIOMD0000000149
type: SBMLModel
species: metaid_0000062
parameter: metaid_0000035
parameter: metaid_0000032
reaction: metaid_0000113
parameter: metaid_0000059
parameter: metaid_0000056
reaction: metaid_0000117
reaction: metaid_0000092
parameter: metaid_0000045
species: metaid_0000069
species: metaid_0000073
species: metaid_0000081
parameter: metaid_0000014
species: metaid_0000064
name: Kim2007_Wnt_ERK_Crosstalk
parameter: metaid_0000018
reaction: metaid_0000095
species: metaid_0000072
area units: metaid_0000005
species: metaid_0000082
has part: GO:0000165
is described by: http://identifiers.org/pubmed/17237813
parameter: metaid_0000031
parameter: metaid_0000011
parameter: metaid_0000027
reaction: metaid_0000112
parameter: metaid_0000024
parameter: metaid_0000004
species: metaid_0000086
parameter: metaid_0000055
reaction: metaid_0000116
parameter: metaid_0000028
parameter: metaid_0000048
reaction: metaid_0000097
time units: metaid_0000127
event: metaid_0000125
parameter: metaid_0000034
parameter: metaid_0000021
reaction: metaid_0000115
parameter: metaid_0000037
reaction: metaid_0000122
has part: hsa04310
reaction: metaid_0000102
parameter: metaid_0000058
compartment: metaid_0000128
reaction: metaid_0000119
reaction: metaid_0000106
reaction: metaid_0000094
reaction: metaid_0000091
reaction: metaid_0000120
parameter: metaid_0000047
volume units: metaid_0000084
parameter: metaid_0000044
species: metaid_0000083
parameter: metaid_0000050
parameter: metaid_0000003
reaction: metaid_0000109
species: metaid_0000066
parameter: metaid_0000130
parameter: metaid_0000007
species: metaid_0000074
species: metaid_0000084
parameter: metaid_0000041
units def: metaid_0000127
species: metaid_0000065
parameter: metaid_0000010
parameter: metaid_0000026
reaction: metaid_0000111
rule: metaid_0000131
parameter: metaid_0000013
parameter: metaid_0000052
parameter: metaid_0000054
parameter: metaid_0000017
reaction: metaid_0000099
parameter: metaid_0000009
reaction: metaid_0000090
species: metaid_0000087
parameter: metaid_0000043
parameter: metaid_0000023

metaid_0000062
type: Species
is version of: Q5TA35
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000060
name: Dsha

metaid_0000060
type: Compartment
is: GO:0005737
constant: true
size: 1.0
spatial dimensions: 3.0
name: cytoplasm

metaid_0000035
type: Parameter
constant: true
value: 15.0

metaid_0000032
type: Parameter
constant: true
value: 1.5

metaid_0000113
type: Reaction
fast: false
name: ERK activation
product: 191662
reactant: 191650
modifier: 191674
is: http://identifiers.org/ec-code/2.7.12.2
is version of: GO:0004708
reversible: false
is version of: GO:0000187
kinetic law: 191686

191662
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000083

metaid_0000083
type: Species
is version of: P28482
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.1103
initial amount: NaN
in compartment: metaid_0000060
name: ERK_ast

191650
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000082

metaid_0000082
type: Species
is version of: P28482
constant: false
boundary condition: false
has only substance units: false
initial concentration: 297.8897
initial amount: NaN
in compartment: metaid_0000060
name: ERK

metaid_0000081
type: Species
is version of: Q02750
constant: false
boundary condition: false
has only substance units: false
initial concentration: 3.8863
initial amount: NaN
in compartment: metaid_0000060
name: MEK_ast

metaid_0000059
type: Parameter
constant: true
value: 15.0

metaid_0000056
type: Parameter
constant: true
value: 1.5

metaid_0000117
type: Reaction
kinetic law: 191866
product: 191854
reactant: 191842
is version of: GO:0016311
fast: false
reversible: false
name: RKIP dephosphorylation

191854
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000085

metaid_0000085
type: Species
is version of: P30086
constant: false
boundary condition: false
has only substance units: false
initial concentration: 418.1788
initial amount: NaN
in compartment: metaid_0000060
name: RKIP

191842
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000086

metaid_0000086
type: Species
is version of: P30086
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.8619
initial amount: NaN
in compartment: metaid_0000060
name: RKIP_ast

metaid_0000092
type: Reaction
product: 190821
name: Dishevelled mediated GSK/Axin/APC complex disassembly
reactant: 190797
reversible: false
product: 190809
kinetic law: 190845
is version of: GO:0030177
fast: false
modifier: 190833

190821
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000065

metaid_0000065
type: Species
is version of: P49841
constant: false
boundary condition: false
has only substance units: false
initial concentration: 49.1372
initial amount: NaN
in compartment: metaid_0000060
name: GSK3beta

190797
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000064

metaid_0000064
type: Species
has part: O15169
is: GO:0030877
constant: false
initial concentration: 0.0076
boundary condition: false
in compartment: metaid_0000060
initial amount: NaN
has part: P49841
has only substance units: false
name: APC/Axin/GSK3beta
has part: O95996

190809
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000066

metaid_0000066
type: Species
initial amount: NaN
has part: O15169
boundary condition: false
in compartment: metaid_0000060
has only substance units: false
initial concentration: 0.0015
name: APC/Axin
has part: O95996
constant: false

metaid_0000045
type: Parameter
constant: true
value: 9.0

metaid_0000069
type: Species
has part: P49841
name: bCatenin_ast/APC_ast/Axin_ast/GSK3beta
in compartment: metaid_0000060
has part: O95996
has part: P35222
boundary condition: false
has part: O15169
initial amount: NaN
initial concentration: 0.002
is: GO:0030877
has only substance units: false
constant: false

metaid_0000073
type: Species
is version of: Q9UJU2
constant: false
boundary condition: false
has only substance units: false
initial concentration: 6.1879
initial amount: NaN
in compartment: metaid_0000128
name: TCF

metaid_0000128
type: Compartment
is: GO:0005634
constant: true
size: 1.0
spatial dimensions: 3.0
name: nucleus

metaid_0000014
type: Parameter
constant: true
value: 120.0

metaid_0000018
type: Parameter
constant: true
value: 0.423

metaid_0000095
type: Reaction
kinetic law: 190965
product: 190953
reactant: 190941
reactant: 190929
is version of: GO:0043623
fast: false
reversible: true
name: GSK/Axin/APC complex reassembly

190953
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000064

190941
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000065

190929
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000066

metaid_0000072
type: Species
is version of: O15169
constant: false
boundary condition: false
has only substance units: false
initial concentration: 8.0E-4
initial amount: NaN
in compartment: metaid_0000060
name: Axin

metaid_0000031
type: Parameter
constant: true
value: 8.0

metaid_0000011
type: Parameter
constant: true
value: 1.0

metaid_0000027
type: Parameter
constant: true
value: 150.0

metaid_0000112
type: Reaction
kinetic law: 191638
product: 191626
reactant: 191614
is version of: GO:0051389
fast: false
reversible: false
name: MEK inactivation

191626
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000080

metaid_0000080
type: Species
is version of: Q02750
constant: false
boundary condition: false
has only substance units: false
initial concentration: 296.1137
initial amount: NaN
in compartment: metaid_0000060
name: MEK

191614
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000081

metaid_0000024
type: Parameter
constant: true
value: 30.0

metaid_0000004
type: Parameter
constant: false
value: 0.0

metaid_0000055
type: Parameter
constant: true
value: 15.0

metaid_0000116
type: Reaction
kinetic law: 191830
product: 191818
reactant: 191806
reactant: 191794
is version of: GO:0005515
fast: false
reversible: true
name: Raf-RKIP complex formation

191818
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000084

metaid_0000084
type: Species
has part: P30086
name: Raf1/RKIP
constant: false
boundary condition: false
initial amount: NaN
initial concentration: 180.9595
in compartment: metaid_0000060
has only substance units: false
has part: P04049

191806
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000085

191794
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000078

metaid_0000078
type: Species
is version of: P04049
constant: false
boundary condition: false
has only substance units: false
initial concentration: 112.5585
initial amount: NaN
in compartment: metaid_0000060
name: Raf-1

metaid_0000028
type: Parameter
constant: true
value: 10.0

metaid_0000048
type: Parameter
constant: true
value: 45.0

metaid_0000097
type: Reaction
kinetic law: 191062
product: 191050
reactant: 191038
reactant: 191026
is: GO:0008013
fast: false
reversible: true
name: bCatenin binding to GSK/Axin/APC complex

191050
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000068

metaid_0000068
type: Species
boundary condition: false
name: bCatenin/APC_Ast/Axin_ast/GSK3beta
initial concentration: 0.002
is: GO:0030877
has only substance units: false
constant: false
has part: P49841
has part: O95996
has part: P35222
has part: O15169
in compartment: metaid_0000060
initial amount: NaN

191038
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000063

metaid_0000063
type: Species
in compartment: metaid_0000060
constant: false
name: APC_ast/Axin_ast/GSK3beta
has part: P49841
is: GO:0030877
initial concentration: 0.0153
has part: O15169
has part: O95996
initial amount: NaN
boundary condition: false
has only substance units: false

191026
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000071

metaid_0000071
type: Species
is version of: P35222
constant: false
boundary condition: false
has only substance units: false
initial concentration: 42.7224
initial amount: NaN
in compartment: metaid_0000128
name: bCatenin

metaid_0000127
type: SBMLUnitsDef
unit: 190712
name: minute

190712
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 60.0
kind: SECOND

metaid_0000125
type: Event
event assignment: 192106
trigger: 192094
use values from trigger time: true

192094
type: Trigger
persistant: true
initial value: true

metaid_0000034
type: Parameter
constant: true
value: 45.0

metaid_0000021
type: Parameter
constant: true
value: 1.0E-6

metaid_0000115
type: Reaction
modifier: 191770
name: Raf/RKIP complex disassembly
product: 191758
is version of: GO:0043624
product: 191746
kinetic law: 191782
reversible: false
reactant: 191734
fast: false

191758
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000086

191746
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000078

191734
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000084

metaid_0000037
type: Parameter
constant: true
value: 15.0

metaid_0000122
type: Reaction
kinetic law: 192058
product: 192046
reactant: 192034
is version of: GO:0016311
fast: false
reversible: false
name: GSK3beta dephosphorylation

192046
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000065

192034
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000088

metaid_0000088
type: Species
is version of: P49841
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.85544
initial amount: NaN
in compartment: metaid_0000060
name: GSK3beta

metaid_0000102
type: Reaction
kinetic law: 191218
reactant: 191206
is version of: GO:0030163
fast: false
reversible: false
name: Unphosphorylated bCatenin degradation

191206
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000071

metaid_0000058
type: Parameter
constant: true
value: 45.0

metaid_0000119
type: Reaction
kinetic law: 191926
reactant: 191914
is version of: GO:0030163
fast: false
reversible: false
name: Factor-X degradation

191914
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000087

metaid_0000087
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 10.263
initial amount: NaN
in compartment: metaid_0000060
name: unknown molecule X

metaid_0000106
type: Reaction
kinetic law: 191386
product: 191374
reactant: 191362
reactant: 191350
is version of: GO:0005515
fast: false
reversible: true
name: APC/bCatenin complex formation

191374
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000075

metaid_0000075
type: Species
initial amount: NaN
in compartment: metaid_0000060
name: bCatenin/APC
initial concentration: 3.4392
has only substance units: false
has part: P35222
constant: false
boundary condition: false
has part: O95996

191362
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000067

metaid_0000067
type: Species
is version of: O95996
constant: false
boundary condition: false
has only substance units: false
initial concentration: 96.6019
initial amount: NaN
in compartment: metaid_0000060
name: APC

191350
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000071

metaid_0000094
type: Reaction
kinetic law: 190917
product: 190905
reactant: 190893
is version of: GO:0016311
fast: false
reversible: false
name: Inactivation of GSK/Axin/APC complex

190905
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000064

190893
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000063

metaid_0000091
type: Reaction
kinetic law: 190785
product: 190772
reactant: 190760
is version of: GO:0030111
fast: false
reversible: false
name: Dishevelled inactivation

190772
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000061

metaid_0000061
type: Species
is version of: Q5TA35
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: metaid_0000060
name: Dshi

190760
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000062

metaid_0000120
type: Reaction
kinetic law: 191974
modifier: 191962
product: 191950
reactant: 191938
is version of: GO:0000185
fast: false
reversible: false
name: Factor-X mediated Raf activation

191950
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000079

metaid_0000079
type: Species
is version of: P04049
constant: false
boundary condition: false
has only substance units: false
initial concentration: 6.486
initial amount: NaN
in compartment: metaid_0000060
name: Raf-1_ast

191938
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000078

metaid_0000047
type: Parameter
constant: true
value: 39.0

metaid_0000044
type: Parameter
constant: true
value: 1.5

metaid_0000050
type: Parameter
constant: true
value: 0.6

metaid_0000003
type: Parameter
constant: true
value: 0.182

metaid_0000109
type: Reaction
kinetic law: 191518
modifier: 191506
product: 191494
reactant: 191482
is version of: GO:0000185
fast: false
reversible: false
name: Raf activation

metaid_0000077
type: Species
is version of: P62070
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000060
name: Rasa

191494
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000079

191482
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000078

metaid_0000130
type: Parameter
constant: false
value: 0.0

metaid_0000007
type: Parameter
constant: true
value: 0.267

metaid_0000074
type: Species
has only substance units: false
initial concentration: 8.8121
in compartment: metaid_0000128
constant: false
boundary condition: false
has part: P35222
has part: Q9UJU2
initial amount: NaN
name: bCatenin/TCF

metaid_0000041
type: Parameter
constant: true
value: 15.0

metaid_0000010
type: Parameter
constant: true
value: 0.909

metaid_0000026
type: Parameter
constant: true
value: 1200.0

metaid_0000111
type: Reaction
modifier: 191590
reversible: false
name: MEK activation
reactant: 191566
is: http://identifiers.org/ec-code/2.7.11.1
fast: false
kinetic law: 191602
product: 191578
is version of: GO:0004709
is version of: GO:0000186

191566
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000080

191578
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000081

metaid_0000013
type: Parameter
constant: true
value: 1.0

metaid_0000052
type: Parameter
constant: true
value: 15.0

metaid_0000054
type: Parameter
constant: true
value: 1.5

metaid_0000017
type: Parameter
constant: true
value: 0.417

metaid_0000099
type: Reaction
kinetic law: 191146
product: 191134
product: 191122
reactant: 191110
is version of: GO:0043624
fast: false
reversible: false
name: GSK.Axin/APC/bCatenin complex disassembly

191134
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000070

metaid_0000070
type: Species
is version of: P35222
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.9881
initial amount: NaN
in compartment: metaid_0000060
name: bCatenin_ast

191122
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000063

191110
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000069

metaid_0000009
type: Parameter
constant: true
value: 0.0909

metaid_0000090
type: Reaction
kinetic law: 190748
product: 190736
reactant: 190724
is version of: GO:0017147
fast: false
reversible: false
name: Dishevelled activation

190736
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000062

190724
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000061

metaid_0000043
type: Parameter
constant: true
value: 15.0

metaid_0000023
type: Parameter
constant: true
value: 1.0

metaid_0000121
type: Reaction
is: GO:0004707
kinetic law: 192022
reactant: 191986
product: 191998
reversible: false
name: ERK mediated GSK3beta phosphorylation
is: GO:0016310
is: http://identifiers.org/ec-code/2.7.11.24
modifier: 192010
fast: false

191986
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000065

191998
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000088

metaid_0000020
type: Parameter
constant: true
value: 8.22E-5

metaid_0000104
type: Reaction
kinetic law: 191290
reactant: 191278
is version of: GO:0030163
fast: false
reversible: false
name: Axin degradation

191278
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000072

metaid_0000036
type: Parameter
constant: true
value: 1.5

metaid_0000101
type: Reaction
kinetic law: 191194
product: 191182
is version of: GO:0006417
fast: false
reversible: false
name: bCatenin synthesis

191182
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000071

metaid_0000016
type: Parameter
constant: true
value: 206.0

metaid_0000076
type: Species
is version of: P62070
constant: false
boundary condition: false
has only substance units: false
initial concentration: 200.0
initial amount: NaN
in compartment: metaid_0000060
name: Rasi

metaid_0000108
type: Reaction
kinetic law: 191470
product: 191458
reactant: 191446
is version of: GO:0032318
fast: false
reversible: false
name: Ras inactivation

191458
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000076

191446
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000077

metaid_0000105
type: Reaction
is version of: GO:0008013
kinetic law: 191338
name: bCatenin/TCF complex formation
reactant: 191314
fast: false
reversible: true
reactant: 191302
is version of: GO:0008134
product: 191326

191314
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000071

191302
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000073

191326
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000074

metaid_0000093
type: Reaction
kinetic law: 190881
product: 190869
reactant: 190857
is version of: GO:0004674
is: http://identifiers.org/ec-code/2.7.11.26
fast: false
reversible: false
name: Activation of GSK/Axin/APC complex

190869
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000063

190857
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000064

metaid_0000126
type: SBMLUnitsDef
unit: 190700
name: nanomole

190700
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000046
type: Parameter
constant: true
value: 0.15

metaid_0000033
type: Parameter
constant: true
value: 15.0

metaid_0000114
type: Reaction
kinetic law: 191722
product: 191710
reactant: 191698
is version of: GO:0000188
fast: false
reversible: false
name: ERK inactivation

191710
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000082

191698
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000083

metaid_0000057
type: Parameter
constant: true
value: 15.0

metaid_0000118
type: Reaction
kinetic law: 191902
modifier: 191890
product: 191878
is version of: GO:0045727
fast: false
reversible: false
name: Unknown factor-X formation

191878
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000087

ORG:
  orgname: California Institute of Technology
n:
  given: Harish
  family: Dharuri

metaid_0000006
type: Parameter
constant: true
value: 0.05

metaid_0000030
type: Parameter
constant: true
value: 15.0

metaid_0000100
type: Reaction
kinetic law: 191170
reactant: 191158
is version of: GO:0030163
fast: false
reversible: false
name: Phosphorylated bCatenin degradation

191158
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000070

metaid_0000015
type: Parameter
constant: true
value: 206.0

metaid_0000012
type: Parameter
constant: true
value: 50.0

metaid_0000051
type: Parameter
constant: true
value: 2.0

metaid_0000039
type: Parameter
constant: true
value: 15.0

metaid_0000019
type: Parameter
constant: true
value: 2.57E-4

metaid_0000096
type: Reaction
kinetic law: 191014
product: 191001
reactant: 190989
reactant: 190977
is version of: GO:0005515
fast: false
reversible: true
name: Axin/APC complex formation

191001
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000066

190989
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000067

190977
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000072

metaid_0000098
type: Reaction
kinetic law: 191098
product: 191086
reactant: 191074
is: GO:0004674
is: http://identifiers.org/ec-code/2.7.11.26
fast: false
reversible: false
name: bCatenin phosphorylation

191086
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000069

191074
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000068

metaid_0000008
type: Parameter
constant: true
value: 0.133

metaid_0000040
type: Parameter
constant: true
value: 1.5

metaid_0000042
type: Parameter
constant: true
value: 45.0

metaid_0000110
type: Reaction
kinetic law: 191554
product: 191542
reactant: 191530
is version of: GO:0051390
fast: false
reversible: false
name: Raf inactivation

191542
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000078

191530
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000079

metaid_0000022
type: Parameter
constant: true
value: 0.167

metaid_0000038
type: Parameter
constant: true
value: 45.0

metaid_0000103
type: Reaction
kinetic law: 191266
modifier: 191254
modifier: 191242
product: 191230
is version of: GO:0045727
fast: false
reversible: false
name: Axin synthesis

191230
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000072

metaid_0000025
type: Parameter
constant: true
value: 1.0

metaid_0000005
type: Parameter
constant: true
value: 0.0182

metaid_0000107
type: Reaction
kinetic law: 191434
modifier: 191422
product: 191410
reactant: 191398
is: GO:0032856
fast: false
reversible: false
name: Ras activation

191410
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000077

191398
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000076

metaid_0000053
type: Parameter
constant: true
value: 0.015

metaid_0000029
type: Parameter
constant: true
value: 9.0

metaid_0000049
type: Parameter
constant: true
value: 12.0

metaid_0000123
type: Event
event assignment: 192082
trigger: 192070
notes: The two events are used to increase the value of wnt from 0 to 1 between time t=500minutes and t=1000minutes.
use values from trigger time: true

192070
type: Trigger
persistant: true
initial value: true

metaid_0000124
type: Parameter
constant: false
value: 0.0

W3 CDTF: Thu Jul 05 17:30:05 BST 2012

W3 CDTF: Tue Jul 10 14:55:45 BST 2007