BIOMD0000000139
type: SBMLModel
species: metaid_0000056
species: metaid_0000055
reaction: metaid_0000114
parameter: metaid_0000005
rule: metaid_0000146
parameter: metaid_0000132
reaction: metaid_0000128
reaction: metaid_0000127
reaction: metaid_0000090
parameter: metaid_0000009
species: metaid_0000046
parameter: metaid_0000039
reaction: metaid_0000096
reaction: metaid_0000086
parameter: metaid_0000135
species: metaid_0000050
parameter: metaid_0000139
species: metaid_0000049
area units: metaid_0000005
parameter: metaid_0000032
parameter: metaid_0000022
parameter: metaid_0000012
species: metaid_0000047
species: metaid_0000041
species: metaid_0000058
species: metaid_0000057
rule: metaid_0000137
parameter: metaid_0000031
reaction: metaid_0000123
reaction: metaid_0000119
reaction: metaid_0000117
reaction: metaid_0000113
reaction: metaid_0000103
reaction: metaid_0000092
reaction: metaid_0000082
reaction: metaid_0000078
reaction: metaid_0000068
reaction: metaid_0000072
parameter: metaid_0000035
parameter: metaid_0000025
parameter: metaid_0000015
parameter: metaid_0000004
reaction: metaid_0000109
parameter: metaid_0000131
reaction: metaid_0000095
species: metaid_0000052
species: metaid_0000060
parameter: metaid_0000029
parameter: metaid_0000019
parameter: metaid_0000008
parameter: metaid_0000038
parameter: metaid_0000028
reaction: metaid_0000075
parameter: metaid_0000141
curated: true
reaction: metaid_0000099
species: metaid_0000051
reaction: metaid_0000126
units def: metaid_0000133
rule: metaid_0000138
species: metaid_0000048
occurs in: http://identifiers.org/taxonomy/10090
is described by: http://identifiers.org/pubmed/12424381
volume units: metaid_0000084
parameter: metaid_0000021
parameter: metaid_0000011
substance units: metaid_0000133
is part of: mmu04660
reaction: metaid_0000081
parameter: metaid_0000034
parameter: metaid_0000024
parameter: metaid_0000014
compartment: metaid_0000040
parameter: metaid_0000030
parameter: metaid_0000020
species: metaid_0000043
parameter: metaid_0000018
species: metaid_0000042
rule: metaid_0000140

metaid_0000056
type: Species
is version of: Q9Z1E3
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000124

metaid_0000124
type: Compartment
is: GO:0005634
constant: true
size: 1.0
spatial dimensions: 3.0

metaid_0000055
type: Species
is version of: P25799
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.001
initial amount: NaN
in compartment: metaid_0000124

metaid_0000114
type: Reaction
kinetic law: 901332
reactant: 901320
is version of: GO:0044257
fast: false
reversible: false
name: IkBeps degradation

901320
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000046

metaid_0000046
type: Species
is version of: O54910
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000040

metaid_0000040
type: Compartment
is: GO:0005737
constant: true
size: 1.0
spatial dimensions: 3.0

metaid_0000005
type: Parameter
constant: true
value: 30.0

metaid_0000132
type: Parameter
constant: false
value: 1.0

metaid_0000128
type: Reaction
kinetic law: 901741
product: 901729
reactant: 901717
is version of: GO:0044257
has part: http://identifiers.org/ec-code/2.7.11.10
fast: false
reversible: false
name: IkBeps degradation

901729
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

metaid_0000050
type: Species
has part: Q60680
in compartment: metaid_0000040
initial amount: NaN
boundary condition: false
constant: false
has only substance units: false
has part: O88522
initial concentration: 0.0
has part: O88351

901717
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000053

metaid_0000053
type: Species
has part: Q60680
initial concentration: 0.0
in compartment: metaid_0000040
initial amount: NaN
has part: O88351
has only substance units: false
constant: false
has part: O54910
boundary condition: false
has part: O88522

metaid_0000127
type: Reaction
kinetic law: 901705
product: 901693
reactant: 901681
is version of: GO:0044257
has part: http://identifiers.org/ec-code/2.7.11.10
fast: false
reversible: false
name: IkBbeta degradation

901693
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

901681
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000051

metaid_0000051
type: Species
initial concentration: 0.0
is version of: O88522
initial amount: NaN
is version of: Q60778
constant: false
has only substance units: false
is version of: O88351
is version of: Q60680
in compartment: metaid_0000040
boundary condition: false

metaid_0000090
type: Reaction
is version of: GO:0005515
product: 900728
reactant: 900704
name: NFkB-IkBeps complex formation
fast: false
kinetic law: 900740
reversible: true
is version of: GO:0043623
reactant: 900716

900728
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000065

metaid_0000065
type: Species
has part: O54910
has part: P25799
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000124

900704
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000055

900716
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000060

metaid_0000060
type: Species
is version of: O54910
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000124

metaid_0000009
type: Parameter
constant: true
value: 1.224

metaid_0000039
type: Parameter
constant: true
value: 0.0072

metaid_0000096
type: Reaction
kinetic law: 900873
reactant: 900861
is version of: GO:0006402
fast: false
reversible: false
name: IkBbeta transcript degradation

900861
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000063

metaid_0000063
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000124

metaid_0000086
type: Reaction
name: NFkB-IkBalpha complex formation
reactant: 900619
fast: false
is version of: GO:0043623
is version of: GO:0005515
product: 900631
kinetic law: 900643
reversible: true
reactant: 900607

900619
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000056

900631
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000057

metaid_0000057
type: Species
has part: Q9Z1E3
has part: P25799
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000124

900607
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000055

metaid_0000135
type: Parameter
constant: false
value: NaN

metaid_0000139
type: Parameter
constant: false
value: NaN

metaid_0000049
type: Species
has part: Q60680
has only substance units: false
initial amount: NaN
has part: Q9Z1E3
in compartment: metaid_0000040
has part: O88351
initial concentration: 0.0
boundary condition: false
has part: P25799
has part: O88522
constant: false

metaid_0000032
type: Parameter
constant: true
value: 2.88

metaid_0000022
type: Parameter
constant: true
value: 0.2448

metaid_0000012
type: Parameter
constant: true
value: 0.00135

metaid_0000047
type: Species
has part: O54910
has part: P25799
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000040

metaid_0000041
type: Species
is version of: Q9Z1E3
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.1
initial amount: NaN
in compartment: metaid_0000040

metaid_0000058
type: Species
is version of: Q60778
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000124

metaid_0000031
type: Parameter
constant: true
value: 0.828

metaid_0000123
type: Reaction
name: IKK binary IkBeps NFkB complex formation
is version of: GO:0043623
is version of: GO:0005515
kinetic law: 901596
reactant: 901560
fast: false
reactant: 901572
product: 901584
reversible: true

901560
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

901572
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000047

901584
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000054

metaid_0000054
type: Species
in compartment: metaid_0000040
has part: O54910
has part: P25799
has part: Q60680
has part: O88351
constant: false
has part: O88522
initial amount: NaN
boundary condition: false
has only substance units: false
initial concentration: 0.0

metaid_0000119
type: Reaction
kinetic law: 901452
product: 901440
reactant: 901428
is version of: GO:0006611
fast: false
reversible: false
name: IkBalpha_NFkB translocation

901440
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000043

metaid_0000043
type: Species
has part: P25799
has part: Q9Z1E3
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000040

901428
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000057

metaid_0000117
type: Reaction
fast: false
product: 901404
reversible: true
reactant: 901380
is version of: GO:0005515
name: IKK-binary IkBalpha NFkB complex formation
reactant: 901392
kinetic law: 901416
is version of: GO:0043623

901404
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000049

901380
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

901392
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000043

metaid_0000113
type: Reaction
kinetic law: 901308
modifier: 901296
product: 901284
is version of: GO:0006412
fast: false
reversible: false
name: IkBeps synthesis

metaid_0000064
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000124

901284
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000046

metaid_0000103
type: Reaction
kinetic law: 901072
product: 901059
reactant: 901046
is version of: GO:0000060
fast: false
reversible: true
name: IkBalpha translocation

901059
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000056

901046
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000041

metaid_0000092
type: Reaction
kinetic law: 900764
product: 900752
is version of: GO:0006351
fast: false
reversible: false
name: IkBalpha transcription

900752
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000062

metaid_0000062
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000124

metaid_0000082
type: Reaction
kinetic law: 900523
product: 900511
reactant: 900499
is version of: GO:0044257
fast: false
reversible: false
name: IkBbeta degradation

900511
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

metaid_0000042
type: Species
is version of: P25799
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.1
initial amount: NaN
in compartment: metaid_0000040

900499
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000045

metaid_0000045
type: Species
has part: Q60778
has part: P25799
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000040

metaid_0000078
type: Reaction
name: NFkB binary IKK IkBeps complex formation
kinetic law: 900402
fast: false
is version of: GO:0005515
reactant: 900378
reactant: 900366
reversible: true
is version of: GO:0043623
product: 900390

900378
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000053

900366
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

900390
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000054

metaid_0000068
type: Reaction
kinetic law: 900114
product: 900102
reactant: 900090
reactant: 900078
is version of: GO:0005515
fast: false
reversible: true
name: NFkB-IkBbeta complex formation

900102
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000045

900090
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000044

metaid_0000044
type: Species
is version of: Q60778
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000040

900078
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

metaid_0000072
type: Reaction
name: NFkB-binary IKK IkBalpha complex formation
kinetic law: 900210
is version of: GO:0043623
product: 900198
fast: false
is version of: GO:0005515
reactant: 900174
reactant: 900186
reversible: true

900198
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000049

900174
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

900186
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000048

metaid_0000048
type: Species
in compartment: metaid_0000040
boundary condition: false
has part: O88522
constant: false
has part: O88351
initial amount: NaN
has part: Q60680
has only substance units: false
initial concentration: 0.0
has part: Q9Z1E3

metaid_0000035
type: Parameter
constant: true
value: 0.624

metaid_0000025
type: Parameter
constant: true
value: 0.012

metaid_0000015
type: Parameter
constant: true
value: 9.25E-5

metaid_0000004
type: Parameter
constant: true
value: 0.03

metaid_0000109
type: Reaction
kinetic law: 901224
product: 901212
reactant: 901200
is version of: GO:0000060
fast: false
reversible: true
name: IkBbeta translocation

901212
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000058

901200
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000044

metaid_0000131
type: Parameter
constant: false
value: 0.0

metaid_0000095
type: Reaction
kinetic law: 900849
product: 900837
is version of: GO:0006351
fast: false
reversible: false
name: IkBbeta transcription

900837
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000063

metaid_0000052
type: Species
has part: Q60680
initial concentration: 0.0
in compartment: metaid_0000040
has part: P25799
boundary condition: false
has part: O88522
initial amount: NaN
has part: O88351
has only substance units: false
constant: false
has part: Q60778

metaid_0000029
type: Parameter
constant: true
value: 0.105

metaid_0000019
type: Parameter
constant: true
value: 0.0

metaid_0000008
type: Parameter
constant: true
value: 0.03

metaid_0000038
type: Parameter
constant: true
value: 0.132

metaid_0000028
type: Parameter
constant: true
value: 0.54

metaid_0000075
type: Reaction
is version of: GO:0005515
reactant: 900282
product: 900294
name: NFkB binary IKK IkBbeta complex formation
reactant: 900270
kinetic law: 900306
reversible: true
is version of: GO:0043623
fast: false

900282
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000051

900294
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000052

900270
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

metaid_0000141
type: Parameter
constant: false
value: NaN

metaid_0000099
type: Reaction
product: 900958
kinetic law: 900970
reactant: 900934
name: IKK-IkBalpha complex formation
reversible: true
is version of: GO:0005515
fast: false
reactant: 900946
is version of: GO:0043623

900958
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000048

900934
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

900946
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000041

metaid_0000126
type: Reaction
kinetic law: 901669
product: 901657
reactant: 901645
is version of: GO:0044257
has part: http://identifiers.org/ec-code/2.7.11.10
fast: false
reversible: false
name: IkBalpha degradation

901657
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

901645
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000048

metaid_0000133
type: SBMLUnitsDef
unit: 900004
name: micro mole

900004
type: SBMLUnit
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE

metaid_0000021
type: Parameter
constant: true
value: 0.075

metaid_0000011
type: Parameter
constant: true
value: 0.66

metaid_0000081
type: Reaction
kinetic law: 900487
product: 900475
reactant: 900463
is version of: GO:0044257
fast: false
reversible: false
name: IkBalpha degradation

900475
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

900463
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000043

metaid_0000034
type: Parameter
constant: true
value: 4.2

metaid_0000024
type: Parameter
constant: true
value: 0.018

metaid_0000014
type: Parameter
constant: true
value: 0.0048

metaid_0000030
type: Parameter
constant: true
value: 11.1

metaid_0000020
type: Parameter
constant: true
value: 1.35

metaid_0000018
type: Parameter
constant: true
value: 0.0

metaid_0000059
type: Species
has part: Q60778
has part: P25799
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000124

metaid_0000077
type: Reaction
reversible: false
reactant: 900318
has part: http://identifiers.org/ec-code/2.7.11.10
name: IkBbeta degradation
kinetic law: 900354
product: 900342
fast: false
is version of: GO:0044257
product: 900330

900318
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000052

900342
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

900330
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

metaid_0000125
type: Reaction
kinetic law: 901633
product: 901621
reactant: 901608
is version of: GO:0006611
fast: false
reversible: false
name: IkBeps_NFkB translocation

901621
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000047

901608
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000065

metaid_0000122
type: Reaction
kinetic law: 901536
product: 901524
reactant: 901512
is version of: GO:0006611
fast: false
reversible: false
name: IkBbeta_NFkB translocation

901536
type: KineticLaw
local parameters: 901548
notes: The sum of "flag_for_after_signal" and "fr_after_trigger" insures that the value of the fraction of "IkBbeta_nuc_ NFkB_nuc" capable of nuclear export is equal to one before the signal is introduced and then follows the rate rule for "fr_after_trigger" after the signal is introduced.

901548
type: LocalParameter
value: 0.0069

901524
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000045

901512
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000059

metaid_0000115
type: Reaction
kinetic law: 901368
product: 901356
reactant: 901344
is version of: GO:0000060
fast: false
reversible: true
name: IkBeps translocation

901356
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000060

901344
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000046

metaid_0000102
type: Reaction
kinetic law: 901033
reactant: 901020
is version of: GO:0044257
fast: false
reversible: false
name: IkBalpha degradation

901020
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000041

metaid_0000003
type: Parameter
constant: true
value: 30.0

metaid_0000108
type: Reaction
kinetic law: 901188
reactant: 901176
is version of: GO:0044257
fast: false
reversible: false
name: IkBbeta degradation

901176
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000044

metaid_0000105
type: Reaction
reactant: 901098
reversible: true
reactant: 901085
kinetic law: 901124
fast: false
is version of: GO:0005515
is version of: GO:0043623
product: 901111
name: IKK-IkBbeta complex formation

901098
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000044

901085
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

901111
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000051

metaid_0000134
type: SBMLUnitsDef
unit: 900017
name: minutes

900017
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 60.0
kind: SECOND

metaid_0000098
type: Reaction
kinetic law: 900922
reactant: 900910
is version of: GO:0006402
fast: false
reversible: false
name: IkBeps transcript degradation

900910
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000064

metaid_0000088
type: Reaction
is version of: GO:0005515
reactant: 900656
reactant: 900668
product: 900680
fast: false
kinetic law: 900692
name: NFkB-IkBbeta complex formation
reversible: true
is version of: GO:0043623

900656
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000055

900668
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000058

900680
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000059

metaid_0000094
type: Reaction
kinetic law: 900825
reactant: 900812
is version of: GO:0006402
fast: false
reversible: false
name: IkBalpha transcript degradation

900812
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000062

metaid_0000084
type: Reaction
kinetic law: 900595
product: 900583
reactant: 900571
is version of: GO:0000060
fast: false
reversible: true
name: NFkB translocation

900583
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000055

900571
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

metaid_0000007
type: Parameter
constant: true
value: 30.0

metaid_0000074
type: Reaction
product: 900246
has part: http://identifiers.org/ec-code/2.7.11.10
name: IkBalpha degradation
is version of: GO:0044257
reactant: 900222
kinetic law: 900258
fast: false
product: 900234
reversible: false

900246
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

900222
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000049

900234
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

metaid_0000037
type: Parameter
constant: true
value: 0.09

metaid_0000027
type: Parameter
constant: true
value: 0.105

metaid_0000017
type: Parameter
constant: true
value: 0.0168

metaid_0000006
type: Parameter
constant: true
value: 0.03

metaid_0000144
type: Parameter
constant: false
value: 0.5

metaid_0000130
type: Event
event assignment: 901813
event assignment: 901801
event assignment: 901789
trigger: 901777
notes: The events section is used to set the IKK signal, the system is allowed to equilibrate for 2000 minutes and IKK is increased to 0.1 uM. trigger value is a parameter that is zero until equilibration and then is set to 1, this in turn is used in the rate rule section for "fr_after_trigger". The latter term corresponds to fr in the paper.
use values from trigger time: true

901777
type: Trigger
persistant: true
initial value: true

metaid_0000129
type: Reaction
kinetic law: 901765
reactant: 901753
fast: false
reversible: false
name: IKK consumption

901753
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

metaid_0000097
type: Reaction
kinetic law: 900898
product: 900886
is version of: GO:0006351
fast: false
reversible: false
name: IkBeps transcription

900886
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000064

metaid_0000010
type: Parameter
constant: true
value: 0.45

metaid_0000136
type: Parameter
constant: false
value: NaN

metaid_0000120
type: Reaction
reactant: 901476
name: IKK binary IkBbeta NFkB complex formation
reversible: true
kinetic law: 901500
fast: false
is version of: GO:0005515
product: 901488
reactant: 901464
is version of: GO:0043623

901476
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000045

901488
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000052

901464
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

metaid_0000111
type: Reaction
product: 901260
name: IKK-IkBeps complex formation
is version of: GO:0005515
fast: false
is version of: GO:0043623
kinetic law: 901272
reactant: 901248
reactant: 901236
reversible: true

901260
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000053

901248
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000046

901236
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

metaid_0000101
type: Reaction
kinetic law: 901007
modifier: 900994
product: 900982
is version of: GO:0006412
fast: false
reversible: false
name: IkBalpha synthesis

900982
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000041

metaid_0000080
type: Reaction
reversible: false
reactant: 900414
fast: false
has part: http://identifiers.org/ec-code/2.7.11.10
name: IkBeps degradation
is version of: GO:0044257
product: 900438
product: 900426
kinetic law: 900451

900414
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000054

900438
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000050

900426
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

metaid_0000066
type: Reaction
kinetic law: 900066
product: 900054
reactant: 900042
reactant: 900030
is version of: GO:0005515
fast: false
reversible: true
name: NFkB-IkBalpha complex formation

900054
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000043

900042
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000041

900030
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

metaid_0000033
type: Parameter
constant: true
value: 0.624

metaid_0000023
type: Parameter
constant: true
value: 0.00678

metaid_0000013
type: Parameter
constant: true
value: 5.4

metaid_0000070
type: Reaction
kinetic law: 900162
product: 900150
reactant: 900138
reactant: 900126
is version of: GO:0005515
fast: false
reversible: true
name: NFkB-IkBeps complex formation

900150
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000047

900138
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000046

900126
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

metaid_0000107
type: Reaction
kinetic law: 901163
modifier: 901150
product: 901137
is version of: GO:0006412
fast: false
reversible: false
name: IkBbeta synthesis

901137
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000044

metaid_0000093
type: Reaction
kinetic law: 900800
modifier: 900788
product: 900776
is version of: GO:0006351
fast: false
reversible: false
name: IkBalpha inducible transcription

900776
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000062

metaid_0000083
type: Reaction
kinetic law: 900559
product: 900547
reactant: 900535
is version of: GO:0044257
fast: false
reversible: false
name: IkBeps degradation

900547
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

900535
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000047

metaid_0000036
type: Parameter
constant: true
value: 0.2442

metaid_0000026
type: Parameter
constant: true
value: 0.36

metaid_0000016
type: Parameter
constant: true
value: 0.99

metaid_0000143
type: Parameter
constant: false
value: 0.5

W3 CDTF: Thu Jul 05 15:45:15 BST 2012

W3 CDTF: Wed May 16 14:37:19 BST 2007

ORG:
  orgname: California Institute of Technology
n:
  given: Harish
  family: Dharuri