Phosphorylated NFAT Calcineurin complex in cytosol
Calcineurin dpdnt NFAT dephosphorylation
Phosphorylated NFAT Calcineurin complex in nucleus
Phosphorylated NFAT Calcineurin complex disassembly
NFAT Calcineurin complex phosphorylation
The model reproduces the calcium oscillation dependent activation-deactivation kinetics of nuclear factor of activated T cells (NFAT) as depicted in Fig 4a of the paper. A simple algorithm in the events section takes care of the calcium oscillation. The model was successfully tested on MathSBML. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
Phosphorylated NFAT Calcineurin complex transport