Release of Ca from the pool into the cytosol
when flag=0, beta=0, flag=1, beta=beta_f*exp[-0.2*(t-tp)]
Constant input of Ca from the extracellular medium
InsP3 modulated release of Ca from the InsP3 sensitive store
According to the legend of Figure4B, beta decays from the initial value beta_f=96% according to the equation beta=beta_f*exp[-0.2*(t-tp)]. and tp=4s.
Transport of cytosolic ca into the extracellular medium
This model is according to the paper Signal-induced Ca2+ oscillations: Properties of a model based on Ca2+-induced Ca2+ release. Figure4B in the paper has been reproduced by RoadRunner and MathSBML. Damped Ca2+ oscillations elicited by a transient pulse of InsP3 applied intracellularly to a resting, non-oscillatory cell. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
Pumping Ca into the InsP3-insensitive store
saturation function of the InsP3 receptor