BIOMD0000000078
type: SBMLModel
reaction: metaid_0000046
reaction: metaid_0000066
has version: hsa04710
species: metaid_0000010
occurs in: http://identifiers.org/taxonomy/40674
is version of: GO:0009649
name: Inhibition of gene
is: MODEL4108701438
function def: metaid_0000004
rule: metaid_0000076
function def: metaid_0000006
reaction: metaid_0000040
reaction: metaid_0000060
reaction: metaid_0000041
reaction: metaid_0000061
substance units: metaid_0000008
reaction: metaid_0000055
reaction: metaid_0000035
species: metaid_0000024
reaction: metaid_0000036
reaction: metaid_0000056
curated: true
name: ceiling
reaction: metaid_0000070
species: metaid_0000015
is described by: http://identifiers.org/pubmed/12775757
species: metaid_0000014
species: metaid_0000018
reaction: metaid_0000028
is derived from: BIOMD0000000021
reaction: metaid_0000029
parameter: metaid_0000077
reaction: metaid_0000044
species: metaid_0000021
reaction: metaid_0000064
reaction: metaid_0000045
reaction: metaid_0000065
volume units: metaid_0000004
reaction: metaid_0000039
reaction: metaid_0000059
notes: This model is described in the paper Toward a detailed computational model for the mammalian circadian clock . In this model only interlocked negative and positive regulation of Per, Cry, Bmal gene are involved. Some initial values were not provided, therefore they were chosen to fit the curves from the paper. Figure2C is re-produced by odeSolver. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
reaction: metaid_0000073
species: metaid_0000011
reaction: metaid_0000030
reaction: metaid_0000050
function def: metaid_0000003
name: Michaelis-Menten(irreversible)
function def: metaid_0000005
rule: metaid_0000078
compartment: metaid_0000009
time units: metaid_0000007
species: metaid_0000025
name: Activation of gene
area units: metaid_0000005
name: Leloup2003_CircClock_LD
species: metaid_0000012
reaction: metaid_0000048
reaction: metaid_0000068
reaction: metaid_0000049
reaction: metaid_0000069
species: metaid_0000016
reaction: metaid_0000027
parameter: metaid_0000075
species: metaid_0000019
reaction: metaid_0000063
reaction: metaid_0000043
reaction: metaid_0000033
reaction: metaid_0000053
reaction: metaid_0000034
reaction: metaid_0000054
units def: metaid_0000008
species: metaid_0000022
function def: metaid_0000074
reaction: metaid_0000071
reaction: metaid_0000072
reaction: metaid_0000026
length unit: length
species: metaid_0000023
reaction: metaid_0000042

metaid_0000046
type: Reaction
kinetic law: 870998
modifier: 870986
product: 870973
is version of: GO:0045893
fast: false
reversible: false
name: Mc synthesis

416562
type: LocalParameter
value: 0.6
name: Kac

416559
type: LocalParameter
value: 4.0

416556
type: LocalParameter
value: 1.1
name: vsc

metaid_0000013
type: Species
has version: O00327
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.9
initial amount: NaN
in compartment: metaid_0000009
name: Bn

metaid_0000009
type: Compartment
is version of: GO:0005623
constant: true
size: 1.0
spatial dimensions: 3.0
name: cell

870973
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000015

metaid_0000015
type: Species
boundary condition: false
initial amount: NaN
constant: false
has only substance units: false
initial concentration: 1.7
name: Mc
in compartment: metaid_0000009
is part of: CHEBI:33699
notes: Initial concentration for Mc got from the value of the curve at time=0 in the paper.

metaid_0000066
type: Reaction
kinetic law: 871529
reactant: 871517
is part of: GO:0051261
fast: false
reversible: false
name: Bn nonspecific degradation

416599
type: LocalParameter
value: 0.01
name: kdn

871517
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000013

metaid_0000010
type: Species
initial concentration: 9.5
notes: The initial concentration of Mb got from the curve in the paper at time=0
boundary condition: false
in compartment: metaid_0000009
is version of: CHEBI:33699
initial amount: NaN
name: Mb
constant: false
has only substance units: false

metaid_0000040
type: Reaction
kinetic law: 870812
product: 870799
reactant: 870787
is version of: GO:0006468
fast: false
reversible: false
name: PCc phosphorylation

416547
type: LocalParameter
value: 0.1
name: Kp

416544
type: LocalParameter
value: 0.4
name: V1pc

870799
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000021

metaid_0000021
type: Species
initial concentration: 0.0
has part: Q16526
constant: false
has only substance units: false
in compartment: metaid_0000009
has part: O15534
has part: Q8IV71
has part: P56645
initial amount: NaN
name: PCcp
boundary condition: false

870787
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

metaid_0000020
type: Species
in compartment: metaid_0000009
has part: P56645
constant: false
has part: Q8IV71
boundary condition: false
initial concentration: 0.0
has part: Q16526
name: PCc
has part: O15534
initial amount: NaN
has only substance units: false

metaid_0000060
type: Reaction
kinetic law: 871373
reactant: 871361
is version of: GO:0051261
fast: false
reversible: false
name: Bc nonspecific degradation

416586
type: LocalParameter
value: 0.01
name: kdn

871361
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000011

metaid_0000011
type: Species
in compartment: metaid_0000009
name: Bc
notes: In order to get the similar shape of the plot,we assigned 2nM as initial concentration for Bc
initial amount: NaN
constant: false
boundary condition: false
has version: O00327
has only substance units: false
initial concentration: 2.0

metaid_0000041
type: Reaction
kinetic law: 870836
reactant: 870824
is part of: GO:0008233
fast: false
reversible: false
name: PCcp specific degradation

416549
type: LocalParameter
value: 0.3
name: Kd

416548
type: LocalParameter
value: 0.7
name: vdpcc

870824
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000021

metaid_0000061
type: Reaction
kinetic law: 871397
reactant: 871385
is version of: GO:0008233
fast: false
reversible: false
name: Bcp specific degradation

416588
type: LocalParameter
value: 0.3
name: Kd

416587
type: LocalParameter
value: 0.5
name: vdbc

871385
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000012

metaid_0000012
type: Species
has version: O00327
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000009
name: Bcp

870307
type: SBMLUnit
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE

metaid_0000055
type: Reaction
kinetic law: 871252
reactant: 871240
is version of: GO:0051261
fast: false
reversible: false
name: Pcp nonspecific degradation

416579
type: LocalParameter
value: 0.01
name: kdn

871240
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000019

metaid_0000019
type: Species
has version: O15534
constant: false
has only substance units: false
has version: O15055
initial concentration: 0.0
in compartment: metaid_0000009
name: Pcp
boundary condition: false
initial amount: NaN
has version: P56645

metaid_0000035
type: Reaction
kinetic law: 870631
modifier: 870619
product: 870607
is: GO:0045893
fast: false
reversible: false
name: Mp synthesis

416533
type: LocalParameter
value: 0.7
name: Kap

416532
type: LocalParameter
value: 4.0

870607
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

metaid_0000017
type: Species
initial amount: NaN
is version of: CHEBI:33699
has only substance units: false
name: Mp
notes: Initial concentration for Mp got from the value of curve at time=0 in the paper.
initial concentration: 2.5
constant: false
in compartment: metaid_0000009
boundary condition: false

metaid_0000024
type: Species
boundary condition: false
has part: Q16526
initial amount: NaN
constant: false
has part: P56645
has part: O15055
has only substance units: false
has part: Q8IV71
name: PCnp
has part: O15534
initial concentration: 0.0
in compartment: metaid_0000009

metaid_0000036
type: Reaction
kinetic law: 870667
modifier: 870655
product: 870643
is version of: GO:0006412
fast: false
reversible: false
name: Mp translated into protein

416534
type: LocalParameter
value: 0.6
name: ksp

870643
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000018

metaid_0000018
type: Species
has version: O15534
initial concentration: 0.0
initial amount: NaN
name: Pc
boundary condition: false
has only substance units: false
constant: false
has version: O15055
in compartment: metaid_0000009
has version: P56645

metaid_0000056
type: Reaction
kinetic law: 871277
reactant: 871264
is version of: GO:0051261
fast: false
reversible: false
name: Ccp nonspecific degradation

416580
type: LocalParameter
value: 0.01
name: kdn

871264
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000016

metaid_0000016
type: Species
initial concentration: 0.0
has version: Q16526
name: Ccp
initial amount: NaN
has only substance units: false
boundary condition: false
has version: Q8IV71
in compartment: metaid_0000009
constant: false

metaid_0000070
type: Reaction
kinetic law: 871673
product: 871661
reactant: 871649
is version of: GO:0006470
fast: false
reversible: false
name: Pcp dephosphorylation

416607
type: LocalParameter
value: 0.1
name: Kdp

416606
type: LocalParameter
value: 0.3
name: V2p

871661
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000018

871649
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000019

metaid_0000014
type: Species
in compartment: metaid_0000009
constant: false
initial amount: NaN
boundary condition: false
has version: Q16526
has version: Q8IV71
name: Cc
has only substance units: false
initial concentration: 0.0

metaid_0000028
type: Reaction
kinetic law: 870403
reactant: 870391
is version of: GO:0051261
fast: false
reversible: false
name: Mb nonspecific degradation

416518
type: LocalParameter
value: 0.01
name: kdmb

870391
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000010

metaid_0000029
type: Reaction
kinetic law: 870439
product: 870427
reactant: 870415
is version of: GO:0006468
fast: false
reversible: false
name: Bc phosphorylation

416523
type: LocalParameter
value: 0.1
name: Kp

416520
type: LocalParameter
value: 0.5
name: V1b

870427
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000012

870415
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000011

metaid_0000077
type: Parameter
constant: false
value: NaN
name: vsp

metaid_0000044
type: Reaction
kinetic law: 870937
reactant: 870925
is version of: GO:0051261
fast: false
reversible: false
name: Bcp nonspecific degradation

416553
type: LocalParameter
value: 0.01
name: kdn

870925
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000012

metaid_0000064
type: Reaction
kinetic law: 871481
reactant: 871469
is version of: GO:0051261
fast: false
reversible: false
name: In nonspecific degration

416593
type: LocalParameter
value: 0.01
name: kdn

871469
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000025

metaid_0000025
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000009
name: In

metaid_0000045
type: Reaction
kinetic law: 870961
reactant: 870949
is version of: GO:0051261
fast: false
reversible: false
name: Bnp nonspecific degradation

416555
type: LocalParameter
value: 0.01
name: kdn

870949
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000023

metaid_0000023
type: Species
is version of: O00327
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000009
name: Bnp

metaid_0000065
type: Reaction
kinetic law: 871505
reactant: 871493
is version of: GO:0008233
fast: false
reversible: false
name: In specific degradation

416598
type: LocalParameter
value: 0.3
name: Kd

416595
type: LocalParameter
value: 0.8
name: vdin

871493
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000025

metaid_0000039
type: Reaction
kinetic law: 870775
product: 870763
reactant: 870751
reactant: 870739
is version of: GO:0043623
fast: false
reversible: true
name: Cc and Pc produce complex Per_Cry

416543
type: LocalParameter
value: 0.2
name: k4

416542
type: LocalParameter
value: 0.4
name: k3

870763
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

870751
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000018

870739
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

metaid_0000059
type: Reaction
kinetic law: 871349
reactant: 871337
is version of: GO:0008233
fast: false
reversible: false
name: PCnp specific degradation

416585
type: LocalParameter
value: 0.3
name: Kd

416584
type: LocalParameter
value: 0.7
name: vdpcn

871337
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000024

metaid_0000073
type: Reaction
kinetic law: 871769
product: 871757
reactant: 871745
is version of: GO:0016311
is version of: GO:0006470
fast: false
reversible: false
name: PCcp dephosphorylation

416612
type: LocalParameter
value: 0.1
name: Kdp

416611
type: LocalParameter
value: 0.1
name: V2pc

871757
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

871745
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000021

metaid_0000030
type: Reaction
kinetic law: 870475
product: 870463
reactant: 870451
is version of: GO:0000060
fast: false
reversible: true
name: Bc transfered from cytosolic to nuclear

416525
type: LocalParameter
value: 0.2
name: k6

416524
type: LocalParameter
value: 0.4
name: k5

870463
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000013

870451
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000011

metaid_0000050
type: Reaction
kinetic law: 871131
reactant: 871118
is version of: GO:0008233
fast: false
reversible: false
name: Mb specific degradation

416571
type: LocalParameter
value: 0.4
name: Kmb

416570
type: LocalParameter
value: 0.8
name: vmb

871118
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000010

870295
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 3600.0
kind: SECOND

metaid_0000048
type: Reaction
kinetic law: 871058
reactant: 871046
is version of: GO:0051261
fast: false
reversible: false
name: Mp nonspecific degradation

416567
type: LocalParameter
value: 0.01
name: kdmp

871046
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

metaid_0000068
type: Reaction
kinetic law: 871601
product: 871589
reactant: 871577
is version of: GO:0006470
fast: false
reversible: false
name: Bnp dephosphorylation

416603
type: LocalParameter
value: 0.1
name: Kdp

416602
type: LocalParameter
value: 0.2
name: V4b

871589
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000013

871577
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000023

metaid_0000049
type: Reaction
kinetic law: 871106
product: 871094
reactant: 871082
reactant: 871070
is version of: GO:0043623
fast: false
reversible: true
name: Per_Cry and Clock_Bmal form inactive complex

416569
type: LocalParameter
value: 0.1
name: k8

416568
type: LocalParameter
value: 0.5
name: k7

871094
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000025

871082
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000013

871070
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

metaid_0000022
type: Species
initial concentration: 1.0
has part: P56645
in compartment: metaid_0000009
has part: Q8IV71
boundary condition: false
has part: Q16526
name: PCn
initial amount: NaN
has part: O15534
constant: false
has only substance units: false

metaid_0000069
type: Reaction
kinetic law: 871637
product: 871625
reactant: 871613
is version of: GO:0006470
fast: false
reversible: false
name: Ccp dephosphorylation

416605
type: LocalParameter
value: 0.1
name: Kdp

416604
type: LocalParameter
value: 0.1
name: V2c

871625
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

871613
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000016

metaid_0000027
type: Reaction
kinetic law: 870379
modifier: 870367
product: 870355
is version of: GO:0006412
fast: false
reversible: false
name: Mb translated into protein

416517
type: LocalParameter
value: 0.12
name: ksb

870355
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000011

metaid_0000075
type: Parameter
constant: false
value: NaN
name: LD

metaid_0000063
type: Reaction
kinetic law: 871457
reactant: 871445
is version of: GO:0008233
fast: false
reversible: false
name: Bnp specific degradation

416592
type: LocalParameter
value: 0.3
name: Kd

416591
type: LocalParameter
value: 0.6
name: vdbn

871445
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000023

metaid_0000043
type: Reaction
kinetic law: 870896
reactant: 870884
is version of: GO:0051261
fast: false
reversible: false
name: PCnp nonspecific degradation

416552
type: LocalParameter
value: 0.01
name: kdn

870884
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000024

metaid_0000033
type: Reaction
kinetic law: 870571
product: 870559
reactant: 870547
is version of: GO:0006468
fast: false
reversible: false
name: Cc phosphorylation

416529
type: LocalParameter
value: 0.1
name: Kp

416528
type: LocalParameter
value: 0.6
name: V1c

870559
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000016

870547
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

metaid_0000053
type: Reaction
kinetic law: 871204
reactant: 871192
is version of: GO:0051261
fast: false
reversible: false
name: Pc nonspecific degradation

416576
type: LocalParameter
value: 0.01
name: kdn

871192
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000018

metaid_0000034
type: Reaction
kinetic law: 870595
reactant: 870583
is version of: GO:0008233
fast: false
reversible: false
name: Ccp specific degradation

416531
type: LocalParameter
value: 0.3
name: Kd

416530
type: LocalParameter
value: 0.7
name: vdcc

870583
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000016

metaid_0000054
type: Reaction
kinetic law: 871228
reactant: 871216
is version of: GO:0051261
fast: false
reversible: false
name: Cc nonspecific degradation

416577
type: LocalParameter
value: 0.12
name: kdnc

871216
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

metaid_0000071
type: Reaction
kinetic law: 871709
product: 871697
reactant: 871685
is version of: GO:0006470
fast: false
reversible: false
name: PCnp dephosphorylation

416609
type: LocalParameter
value: 0.1
name: Kdp

416608
type: LocalParameter
value: 0.1
name: V4pc

871697
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

871685
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000024

metaid_0000072
type: Reaction
kinetic law: 871733
reactant: 871721
has version: GO:0051261
fast: false
reversible: false
name: PCn nonspecific degradation

416610
type: LocalParameter
value: 0.01
name: kdn

871721
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

metaid_0000026
type: Reaction
kinetic law: 870343
modifier: 870331
product: 870319
is version of: GO:0045892
fast: false
reversible: false
name: Mb synthesized

416516
type: LocalParameter
value: 2.0

416515
type: LocalParameter
value: 2.2
name: Kib

416514
type: LocalParameter
value: 1.0

870319
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000010

metaid_0000042
type: Reaction
kinetic law: 870872
product: 870860
reactant: 870848
is version of: GO:0000060
fast: false
reversible: true
name: PCc transfered into nuclear

416551
type: LocalParameter
value: 0.2
name: k2

416550
type: LocalParameter
value: 0.4
name: k1

870860
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

870848
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

metaid_0000062
type: Reaction
kinetic law: 871433
product: 871421
reactant: 871409
is version of: GO:0006468
fast: false
reversible: false
name: Bn phosphorylation

416590
type: LocalParameter
value: 0.1
name: Kp

416589
type: LocalParameter
value: 0.5
name: V3b

871421
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000023

871409
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000013

metaid_0000067
type: Reaction
kinetic law: 871565
product: 871553
reactant: 871541
is version of: GO:0006470
fast: false
reversible: false
name: Bcp dephosphorylation

416601
type: LocalParameter
value: 0.1
name: Kdp

416600
type: LocalParameter
value: 0.1
name: V2b

871553
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000011

871541
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000012

metaid_0000047
type: Reaction
kinetic law: 871034
product: 871022
reactant: 871010
is version of: GO:0006468
fast: false
reversible: false
name: PCn phosphorylation

416566
type: LocalParameter
value: 0.1
name: Kp

416563
type: LocalParameter
value: 0.4
name: V3pc

871022
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000024

871010
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

metaid_0000037
type: Reaction
kinetic law: 870691
reactant: 870679
is version of: GO:0008233
fast: false
reversible: false
name: Pcp specific degradation

416539
type: LocalParameter
value: 0.3
name: Kd

416536
type: LocalParameter
value: 0.7
name: vdpc

870679
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000019

metaid_0000057
type: Reaction
kinetic law: 871301
reactant: 871289
is version of: GO:0051261
fast: false
reversible: false
name: PCcp nonspecific degradation

416581
type: LocalParameter
value: 0.01
name: kdn

871289
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000021

metaid_0000038
type: Reaction
kinetic law: 870727
product: 870715
reactant: 870703
is version of: GO:0006468
fast: false
reversible: false
name: Pc phosphorylation

416541
type: LocalParameter
value: 0.1
name: Kp

416540
type: LocalParameter
value: 0.4
name: V1p

870715
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000019

870703
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000018

metaid_0000058
type: Reaction
kinetic law: 871325
reactant: 871313
is version of: GO:0051261
fast: false
reversible: false
name: PCc nonspecific degradation

416583
type: LocalParameter
value: 0.01
name: kdn

871313
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

metaid_0000031
type: Reaction
kinetic law: 870511
modifier: 870499
product: 870487
is version of: GO:0006412
fast: false
reversible: false
name: Mc translated into protein

416526
type: LocalParameter
value: 1.6
name: ksc

870487
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

metaid_0000051
type: Reaction
kinetic law: 871155
reactant: 871143
is version of: GO:0008233
fast: false
reversible: false
name: Mc specific degradation

416573
type: LocalParameter
value: 0.4
name: Kmc

416572
type: LocalParameter
value: 1.0
name: vmc

871143
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000015

metaid_0000032
type: Reaction
kinetic law: 870535
reactant: 870523
is version of: GO:0051261
fast: false
reversible: false
name: Mc nonspecific degradation

416527
type: LocalParameter
value: 0.01
name: kdmc

870523
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000015

metaid_0000052
type: Reaction
kinetic law: 871180
reactant: 871167
is part of: GO:0008233
fast: false
reversible: false
name: Mp specific degradation

416575
type: LocalParameter
value: 0.31
name: Kmp

416574
type: LocalParameter
value: 1.1
name: vmp

871167
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

ORG:
  orgname: University of Oxford
n:
  given: Enuo
  family: He

W3 CDTF: Wed Jul 11 19:31:48 BST 2012

W3 CDTF: Tue Oct 17 16:43:58 BST 2006