BIOMD0000000070
type: SBMLModel
reaction: metaid_0000062
species: metaid_0000025
species: metaid_0000038
species: metaid_0000029
species: metaid_0000011
reaction: metaid_0000049
reaction: metaid_0000058
species: metaid_0000024
species: metaid_0000035
reaction: metaid_0000073
species: metaid_0000028
species: metaid_0000039
reaction: metaid_0000085
species: metaid_0000041
species: metaid_0000036
species: metaid_0000005
reaction: metaid_0000053
reaction: metaid_0000068
reaction: metaid_0000083
reaction: metaid_0000070
species: metaid_0000022
species: metaid_0000033
species: metaid_0000043
reaction: metaid_0000079
reaction: metaid_0000066
reaction: metaid_0000051
species: metaid_0000019
reaction: metaid_0000063
species: metaid_0000046
units def: metaid_0000087
has part: REACT 1859
species: metaid_0000009
reaction: metaid_0000077
name: Holzhutter2004_Erythrocyte_Metabolism
reaction: metaid_0000061
reaction: metaid_0000057
volume units: metaid_0000323
species: metaid_0000026
species: metaid_0000037
species: metaid_0000047
reaction: metaid_0000074
has part: GO:0006096
reaction: metaid_0000055
reaction: metaid_0000067
species: metaid_0000042
area units: area
species: metaid_0000012
curated: true
species: metaid_0000006
species: metaid_0000016
length unit: length
reaction: metaid_0000072
units def: metaid_0000091
time units: metaid_0000088
reaction: metaid_0000065
has part: hsa00010
reaction: metaid_0000052
species: metaid_0000040
species: metaid_0000044
species: metaid_0000004
compartment: metaid_0000003
reaction: metaid_0000082
species: metaid_0000010
has part: hsa00480
occurs in: http://identifiers.org/taxonomy/9606
reaction: metaid_0000078
species: metaid_0000007
reaction: metaid_0000050
species: metaid_0000034
reaction: metaid_0000059
reaction: metaid_0000080
has part: REACT 1383
notes: . . . SBML level 2 code generated for the JWS Online project by Jacky Snoep using PySCeS Run this model online at http://jjj.biochem.sun.ac.za To cite JWS Online please refer to: Olivier, B.G. and Snoep, J.L. (2004) Web-based modelling using JWS Online , Bioinformatics, 20:2143-2144 . . . . . . Biomodels Curation The model simulates the flux values as given for "kinetic model" in Table 1 of the paper. The model was successfully tested on Jarnac.
has part: hsa00030
reaction: metaid_0000076
has part: GO:0006098
reaction: metaid_0000060
species: metaid_0000013
species: metaid_0000023

metaid_0000062
type: Reaction
reactant: 848571
name: Lactate dehydrogenase
is: REACT 178
reversible: true
kinetic law: 848608
product: 848596
is version of: http://identifiers.org/ec-code/1.1.1.27
reactant: 848559
is: R00703
product: 848583
fast: false

848571
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

metaid_0000020
type: Species
is: CHEBI:15361
is: C00022
boundary condition: false
has only substance units: false
initial amount: NaN
in compartment: metaid_0000003
initial concentration: 0.084
constant: false
name: Pyruvate

metaid_0000003
type: Compartment
is: GO:0005737
constant: true
size: 1.0
spatial dimensions: 3.0
name: cytoplasm

848632
type: LocalParameter
units: dimensionless
value: 9090.0

848620
type: LocalParameter
units: metaid_0000092
value: 2800000.0

metaid_0000092
type: SBMLUnitsDef
unit: 846896
unit: 846884
unit: 846872
name: per_mM_hour

846896
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 3600.0
kind: SECOND

846884
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE

846872
type: SBMLUnit
exponent: -1.0
scale: -3
multipler: 1.0
kind: MOLE

848596
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000013

metaid_0000013
type: Species
boundary condition: false
name: NAD
initial amount: NaN
has only substance units: false
is: C00003
in compartment: metaid_0000003
is: CHEBI:15846
constant: false
initial concentration: 0.0653

848559
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000015

metaid_0000015
type: Species
in compartment: metaid_0000003
name: NADH
is: CHEBI:16908
has only substance units: false
is: C00004
initial concentration: 2.0E-4
initial amount: NaN
constant: false
boundary condition: false

848583
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000021

metaid_0000021
type: Species
is: C00256
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.6803
initial amount: NaN
in compartment: metaid_0000003
name: Lactate

metaid_0000025
type: Species
constant: false
name: ADP
initial amount: NaN
initial concentration: 0.25
boundary condition: false
is: C00008
in compartment: metaid_0000003
is: CHEBI:16761
has only substance units: false

metaid_0000038
type: Species
constant: false
in compartment: metaid_0000003
has part: C00006
has only substance units: false
has part: C00017
name: Protein1 bound NADP
initial concentration: 0.0
has part: CHEBI:36080
has part: CHEBI:18009
initial amount: NaN
boundary condition: false

metaid_0000029
type: Species
boundary condition: false
is: C00051
is: CHEBI:16856
in compartment: metaid_0000003
constant: false
name: Reduced Glutathione
initial amount: NaN
has only substance units: false
initial concentration: 3.1136

metaid_0000011
type: Species
initial concentration: 0.1492
is: C00111
initial amount: NaN
constant: false
name: Dihydroxyacetone phosphate
has only substance units: false
boundary condition: false
is: CHEBI:16108
in compartment: metaid_0000003

metaid_0000049
type: Reaction
kinetic law: 846933
product: 846920
reactant: 846908
is: REACT 2092
is version of: GO:0046323
fast: false
reversible: true
name: Glucose transport

846994
type: LocalParameter
units: dimensionless
value: 0.54

846982
type: LocalParameter
units: metaid_0000089
value: 6.9

metaid_0000089
type: SBMLUnitsDef
unit: 846812
unit: 846799
name: mM

846812
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE

846799
type: SBMLUnit
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE

846970
type: LocalParameter
units: dimensionless
value: 1.0

846957
type: LocalParameter
units: metaid_0000089
value: 1.7

846945
type: LocalParameter
units: metaid_0000090
value: 33.6

metaid_0000090
type: SBMLUnitsDef
unit: 846848
unit: 846836
unit: 846824
name: mM_per_hour

846848
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 3600.0
kind: SECOND

846836
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE

846824
type: SBMLUnit
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE

846920
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000004

metaid_0000004
type: Species
has only substance units: false
initial amount: NaN
is: C00293
boundary condition: false
initial concentration: 4.5663
in compartment: metaid_0000003
constant: false
name: Glucose in
is: CHEBI:17234

846908
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000047

metaid_0000047
type: Species
constant: false
name: Glucose outside
is: C00293
initial amount: NaN
in compartment: metaid_0000003
is: CHEBI:17234
boundary condition: true
has only substance units: false
initial concentration: 5.0

metaid_0000058
type: Reaction
product: 848145
kinetic law: 848170
reversible: true
modifier: 848158
product: 848133
reactant: 848121
name: Bisphosphoglycerate phosphatase
is: R01516
is version of: http://identifiers.org/ec-code/3.1.3.13
fast: false

848145
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000012

metaid_0000012
type: Species
is: CHEBI:35780
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.9992
initial amount: NaN
in compartment: metaid_0000003
name: Phosphate

848206
type: LocalParameter
units: metaid_0000089
value: 0.2

848194
type: LocalParameter
units: dimensionless
value: 100000.0

848182
type: LocalParameter
units: metaid_0000090
value: 0.53

metaid_0000037
type: Species
in compartment: metaid_0000003
name: MgGri23P2
has only substance units: false
constant: false
boundary condition: false
has part: C00305
initial concentration: 0.5
initial amount: NaN
has part: C01159
has part: CHEBI:25107
has part: CHEBI:17720

848133
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000016

metaid_0000016
type: Species
is: CHEBI:17794
name: 3-Phospho-D-glycerate
is: C00197
boundary condition: false
initial concentration: 0.0658
has only substance units: false
constant: false
initial amount: NaN
in compartment: metaid_0000003

848121
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

metaid_0000017
type: Species
constant: false
has only substance units: false
is: C01159
initial amount: NaN
name: 2,3-Bisphospho-D-glycerate
boundary condition: false
is: CHEBI:17720
initial concentration: 2.0601
in compartment: metaid_0000003

metaid_0000024
type: Species
in compartment: metaid_0000003
name: AMP
has only substance units: false
initial amount: NaN
is: C00020
initial concentration: 0.0
is: CHEBI:16027
constant: false
boundary condition: false

metaid_0000035
type: Species
has only substance units: false
name: ATP
boundary condition: false
is: CHEBI:15422
constant: false
is: C00002
initial concentration: 0.25
in compartment: metaid_0000003
initial amount: NaN

metaid_0000073
type: Reaction
reversible: true
fast: false
is version of: http://identifiers.org/ec-code/2.2.1.2
product: 849861
is: R01827
reactant: 849837
name: Transaldolase
is: REACT 479
reactant: 849825
kinetic law: 849873
product: 849849

849861
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000008

metaid_0000008
type: Species
is: C05345
name: Fructose 6-phosphate
boundary condition: false
in compartment: metaid_0000003
initial concentration: 0.0153
is: CHEBI:16084
initial amount: NaN
constant: false
has only substance units: false

849837
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000032

metaid_0000032
type: Species
is: C05382
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0154
initial amount: NaN
in compartment: metaid_0000003
name: Sedoheptulose 7-phosphate

849825
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000010

metaid_0000010
type: Species
in compartment: metaid_0000003
boundary condition: false
initial amount: NaN
is: C00118
is: CHEBI:29052
initial concentration: 0.0061
name: Glyceraldehyde 3-phosphate
constant: false
has only substance units: false

849897
type: LocalParameter
units: dimensionless
value: 1.05

849909
type: LocalParameter
units: metaid_0000089
value: 0.00823

849921
type: LocalParameter
units: metaid_0000089
value: 0.04765

849885
type: LocalParameter
units: metaid_0000090
value: 27.2

849945
type: LocalParameter
units: metaid_0000089
value: 0.1733

849969
type: LocalParameter
units: metaid_0000089
value: 0.006095

849933
type: LocalParameter
units: dimensionless
value: 0.4653

849957
type: LocalParameter
units: dimensionless
value: 0.8683

849981
type: LocalParameter
units: dimensionless
value: 2.524

849849
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000033

metaid_0000033
type: Species
initial amount: NaN
initial concentration: 0.0063
is: C00279
is: CHEBI:16897
constant: false
in compartment: metaid_0000003
has only substance units: false
name: Erythrose 4-phosphate
boundary condition: false

metaid_0000028
type: Species
initial concentration: 4.0E-4
is: CHEBI:17858
name: Oxidized Glutathione
boundary condition: false
has only substance units: false
constant: false
initial amount: NaN
in compartment: metaid_0000003
is: C00127

metaid_0000039
type: Species
name: Protein1
has only substance units: false
initial amount: NaN
constant: false
in compartment: metaid_0000003
is version of: C00017
boundary condition: false
initial concentration: 0.0
is version of: CHEBI:36080

metaid_0000085
type: Reaction
kinetic law: 850921
product: 850909
product: 850897
reactant: 850885
fast: false
reversible: true
name: P2NADP dissociation

850945
type: LocalParameter
units: metaid_0000089
value: 1.0E-5

850933
type: LocalParameter
units: metaid_0000091
value: 1.0E7

metaid_0000091
type: SBMLUnitsDef
unit: 846860
name: hour_inverse

846860
type: SBMLUnit
exponent: -1.0
scale: 0
multipler: 3600.0
kind: SECOND

850909
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000023

metaid_0000023
type: Species
constant: false
initial concentration: 0.0
name: NADP
boundary condition: false
in compartment: metaid_0000003
is: CHEBI:18009
has only substance units: false
is: C00006
initial amount: NaN

850897
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

metaid_0000042
type: Species
name: Protein2
constant: false
initial concentration: 0.0
is version of: C00017
has only substance units: false
is version of: CHEBI:36080
boundary condition: false
in compartment: metaid_0000003
initial amount: NaN

850885
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000041

metaid_0000041
type: Species
initial concentration: 0.0
in compartment: metaid_0000003
initial amount: NaN
has part: CHEBI:18009
has part: CHEBI:36080
name: Protein2 bound NADP
boundary condition: false
has part: C00017
constant: false
has part: C00006
has only substance units: false

metaid_0000036
type: Species
initial amount: NaN
in compartment: metaid_0000003
boundary condition: false
has only substance units: false
constant: false
is: C00305
name: Mg
initial concentration: 0.8
is: CHEBI:25107

metaid_0000005
type: Species
has only substance units: false
has part: C00305
initial amount: NaN
constant: false
has part: CHEBI:15422
in compartment: metaid_0000003
initial concentration: 1.4
boundary condition: false
has part: CHEBI:25107
name: MgATP
has part: C00002

metaid_0000053
type: Reaction
is: R01070
product: 847550
product: 847538
is: REACT 1602
reactant: 847526
kinetic law: 847562
name: Aldolase
reversible: true
fast: false
is version of: http://identifiers.org/ec-code/4.1.2.13

847550
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000011

847538
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000010

847526
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000009

metaid_0000009
type: Species
is: CHEBI:28013
initial concentration: 0.0097
is: C05378
in compartment: metaid_0000003
constant: false
boundary condition: false
name: Fructose 1,6-phosphate
initial amount: NaN
has only substance units: false

847648
type: LocalParameter
units: metaid_0000089
value: 0.176

847636
type: LocalParameter
units: metaid_0000089
value: 0.0364

847624
type: LocalParameter
units: metaid_0000089
value: 0.1906

847612
type: LocalParameter
units: metaid_0000089
value: 0.0572

847599
type: LocalParameter
units: metaid_0000089
value: 0.114

847586
type: LocalParameter
units: metaid_0000089
value: 0.0071

847574
type: LocalParameter
units: metaid_0000090
value: 98.91000366

metaid_0000068
type: Reaction
is: REACT 2220
kinetic law: 849354
is version of: http://identifiers.org/ec-code/1.8.1.7
reversible: true
is: R00094
name: Glutathione reductase
product: 849342
reactant: 849306
fast: false
product: 849330
reactant: 849318

849427
type: LocalParameter
units: dimensionless
value: 1.04

849415
type: LocalParameter
units: metaid_0000089
value: 0.07

849403
type: LocalParameter
units: metaid_0000089
value: 20.0

849391
type: LocalParameter
units: metaid_0000089
value: 0.00852

849379
type: LocalParameter
units: metaid_0000089
value: 0.0652

849367
type: LocalParameter
units: metaid_0000090
value: 90.0

849342
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000023

849306
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000028

849330
type: SpeciesReference
stoichiometry: 2.0
species: metaid_0000029

849318
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

metaid_0000022
type: Species
is: C00005
is: CHEBI:16474
boundary condition: false
name: NADPH
initial amount: NaN
constant: false
initial concentration: 0.004
has only substance units: false
in compartment: metaid_0000003

metaid_0000083
type: Reaction
kinetic law: 850777
product: 850765
product: 850753
reactant: 850741
fast: false
reversible: true
name: P1NADP dissociation

850801
type: LocalParameter
units: metaid_0000089
value: 2.0E-4

850789
type: LocalParameter
units: metaid_0000091
value: 1.0E7

850765
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000023

850753
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000039

850741
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000038

metaid_0000070
type: Reaction
kinetic law: 849512
name: Phosphoribulose epimerase
is: R01529
reversible: true
product: 849500
reactant: 849488
is version of: http://identifiers.org/ec-code/5.1.3.1
is: REACT 1522
fast: false

849560
type: LocalParameter
units: metaid_0000089
value: 0.5

849548
type: LocalParameter
units: metaid_0000089
value: 0.19

849536
type: LocalParameter
units: dimensionless
value: 2.7

849524
type: LocalParameter
units: metaid_0000090
value: 4634.0

849500
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030

metaid_0000030
type: Species
in compartment: metaid_0000003
initial concentration: 0.0127
name: Xylulose 5-phosphate
is: C00231
constant: false
has only substance units: false
boundary condition: false
initial amount: NaN
is: CHEBI:16332

849488
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000027

metaid_0000027
type: Species
initial amount: NaN
boundary condition: false
in compartment: metaid_0000003
is: C00199
name: Ribulose 5-phosphate
is: CHEBI:17363
has only substance units: false
constant: false
initial concentration: 0.0047

metaid_0000043
type: Species
constant: false
has only substance units: false
has part: C00017
initial concentration: 0.024
boundary condition: false
has part: CHEBI:36080
name: Protein2 bound NADPH
has part: CHEBI:16474
initial amount: NaN
has part: C00005
in compartment: metaid_0000003

metaid_0000079
type: Reaction
kinetic law: 850489
product: 850477
product: 850465
reactant: 850453
is version of: GO:0006754
fast: false
reversible: true
name: MgATP dissociation

850513
type: LocalParameter
units: metaid_0000089
value: 0.072

850501
type: LocalParameter
units: metaid_0000091
value: 1.0E7

850477
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000035

850465
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000036

850453
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000005

metaid_0000066
type: Reaction
is: R00835
reactant: 848908
modifier: 848956
fast: false
is version of: http://identifiers.org/ec-code/1.1.1.49
modifier: 848981
product: 848944
reactant: 848920
name: Glucose 6-phosphate dehydrogenase
has version: REACT 1125
product: 848932
modifier: 848968
has version: REACT 1868
modifier: 848993
reversible: true
kinetic law: 849005

848908
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000006

metaid_0000006
type: Species
initial amount: NaN
boundary condition: false
constant: false
initial concentration: 0.0394
is: CHEBI:17665
in compartment: metaid_0000003
is: C00668
has only substance units: false
name: Glucose 6-phosphate

848944
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

848920
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000023

848932
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000026

metaid_0000026
type: Species
boundary condition: false
is: C01236
initial concentration: 0.025
is: CHEBI:16938
initial amount: NaN
name: Phospho-D-glucono-1,5-lactone
in compartment: metaid_0000003
has only substance units: false
constant: false

849089
type: LocalParameter
units: metaid_0000089
value: 2.289

849077
type: LocalParameter
units: metaid_0000089
value: 0.00312

849065
type: LocalParameter
units: metaid_0000089
value: 0.749

849053
type: LocalParameter
units: dimensionless
value: 2000.0

849041
type: LocalParameter
units: metaid_0000089
value: 0.00367

849029
type: LocalParameter
units: metaid_0000089
value: 0.0667

849017
type: LocalParameter
units: metaid_0000090
value: 162.0

metaid_0000051
type: Reaction
reversible: true
is: R00771
is: REACT 1164
fast: false
kinetic law: 847261
product: 847249
reactant: 847236
is version of: http://identifiers.org/ec-code/5.3.1.9
name: Glucosephosphate isomerase

847309
type: LocalParameter
units: metaid_0000089
value: 0.071

847297
type: LocalParameter
units: metaid_0000089
value: 0.182

847285
type: LocalParameter
units: dimensionless
value: 0.3925

847273
type: LocalParameter
units: metaid_0000090
value: 935.0

847249
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000008

847236
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000006

metaid_0000019
type: Species
is: C00074
initial amount: NaN
is: CHEBI:18021
has only substance units: false
name: Phosphoenolpyruvate
boundary condition: false
constant: false
initial concentration: 0.0109
in compartment: metaid_0000003

metaid_0000063
type: Reaction
fast: false
reversible: true
reactant: 848644
kinetic law: 848692
is version of: http://identifiers.org/ec-code/1.1.1.27
product: 848668
reactant: 848656
product: 848680
name: Lactate dehydrogenase

848644
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

848716
type: LocalParameter
units: dimensionless
value: 14181.8

848704
type: LocalParameter
units: metaid_0000092
value: 243.4

848668
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000021

848656
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

848680
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000023

metaid_0000046
type: Species
in compartment: metaid_0000003
boundary condition: true
is: CHEBI:32816
initial amount: NaN
has only substance units: false
name: External Pyruvate
initial concentration: 0.084
is: C00022
constant: false

metaid_0000087
type: SBMLUnitsDef
unit: 846775
name: millimole

846775
type: SBMLUnit
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE

metaid_0000077
type: Reaction
kinetic law: 850357
product: 850345
reactant: 850333
is version of: GO:0009935
fast: false
reversible: true
name: Lactate exchange

850381
type: LocalParameter
units: dimensionless
value: 1.0

850369
type: LocalParameter
units: metaid_0000091
value: 10000.0

850345
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000021

850333
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000045

metaid_0000045
type: Species
is: C00256
constant: false
boundary condition: true
has only substance units: false
initial concentration: 1.68
initial amount: NaN
in compartment: metaid_0000003
name: External Lactate

metaid_0000061
type: Reaction
modifier: 848450
reactant: 848402
reactant: 848390
is: REACT 1911
product: 848426
reversible: true
name: Pyruvate kinase
modifier: 848438
fast: false
product: 848414
is version of: http://identifiers.org/ec-code/2.7.1.40
kinetic law: 848463
is: R00200

848402
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000007

metaid_0000007
type: Species
boundary condition: false
has part: CHEBI:25107
initial concentration: 0.1
initial amount: NaN
constant: false
has only substance units: false
has part: C00305
in compartment: metaid_0000003
has part: CHEBI:16761
name: MgADP
has part: C00008

848390
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000019

848426
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

848414
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000005

848547
type: LocalParameter
units: metaid_0000089
value: 0.005

848535
type: LocalParameter
units: metaid_0000089
value: 3.39

848523
type: LocalParameter
units: dimensionless
value: 19.0

848511
type: LocalParameter
units: metaid_0000089
value: 0.474

848499
type: LocalParameter
units: metaid_0000089
value: 0.225

848487
type: LocalParameter
units: dimensionless
value: 13790.0

848475
type: LocalParameter
units: metaid_0000090
value: 570.0

metaid_0000057
type: Reaction
reversible: true
fast: false
kinetic law: 848073
name: Bisphosphoglycerate mutase
reactant: 848037
product: 848049
is: R01662
is version of: http://identifiers.org/ec-code/5.4.2.4
modifier: 848061

848109
type: LocalParameter
units: metaid_0000089
value: 0.04

848097
type: LocalParameter
units: dimensionless
value: 100000.0

848085
type: LocalParameter
units: metaid_0000091
value: 76000.0

848037
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

metaid_0000014
type: Species
initial amount: NaN
initial concentration: 5.0E-4
is: CHEBI:16001
is: C00236
has only substance units: false
constant: false
in compartment: metaid_0000003
name: 1,3-Bisphospho-D-glycerate
boundary condition: false

848049
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

metaid_0000074
type: Reaction
kinetic law: 850043
is: R01049
fast: false
product: 850030
name: Phosphoribosylpyrophosphate synthetase
reactant: 850005
reactant: 849993
is version of: http://identifiers.org/ec-code/2.7.6.1
product: 850017
is: REACT 2023
reversible: true

850091
type: LocalParameter
units: metaid_0000089
value: 0.57

850079
type: LocalParameter
units: metaid_0000089
value: 0.03

850067
type: LocalParameter
units: dimensionless
value: 100000.0

850055
type: LocalParameter
units: metaid_0000090
value: 1.1

850030
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000044

metaid_0000044
type: Species
is: CHEBI:17111
initial amount: NaN
in compartment: metaid_0000003
boundary condition: true
initial concentration: 1.0
is: C00119
name: PRPP
constant: false
has only substance units: false

850005
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

metaid_0000031
type: Species
name: Ribose 5-phosphate
is: C00117
is: CHEBI:17797
initial amount: NaN
initial concentration: 0.014
in compartment: metaid_0000003
has only substance units: false
constant: false
boundary condition: false

849993
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000005

850017
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000034

metaid_0000034
type: Species
boundary condition: false
in compartment: metaid_0000003
initial concentration: 0.0
initial amount: NaN
name: MgAMP
has only substance units: false
has part: C00020
has part: C00305
has part: CHEBI:16027
constant: false
has part: CHEBI:25107

metaid_0000055
type: Reaction
product: 847782
is: R01061
product: 847794
reactant: 847770
reactant: 847757
reactant: 847745
fast: false
reversible: true
is: REACT 1847
is version of: http://identifiers.org/ec-code/1.2.1.12
name: Glyceraldehyde 3-phosphate dehydrogenase
kinetic law: 847806

847782
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000015

847794
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

847770
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000013

847757
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000012

847745
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000010

847891
type: LocalParameter
units: metaid_0000089
value: 0.0035

847879
type: LocalParameter
units: metaid_0000089
value: 0.0083

847866
type: LocalParameter
units: dimensionless
value: 1.92E-4

847854
type: LocalParameter
units: metaid_0000089
value: 3.9

847842
type: LocalParameter
units: metaid_0000089
value: 0.005

847830
type: LocalParameter
units: metaid_0000089
value: 0.05

847818
type: LocalParameter
units: metaid_0000090
value: 4300.0

metaid_0000067
type: Reaction
has part: REACT 611
reactant: 849114
has part: R01528
is version of: http://identifiers.org/ec-code/1.1.1.44
modifier: 849186
modifier: 849150
has part: R02035
has part: REACT 2072
modifier: 849174
name: Phosphogluconate dehydrogenase
kinetic law: 849198
product: 849126
reversible: true
fast: false
reactant: 849101
product: 849138
modifier: 849162

849114
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000023

849294
type: LocalParameter
units: metaid_0000089
value: 0.0045

849282
type: LocalParameter
units: metaid_0000089
value: 0.058

849270
type: LocalParameter
units: metaid_0000089
value: 0.154

849258
type: LocalParameter
units: metaid_0000089
value: 0.12

849246
type: LocalParameter
units: dimensionless
value: 141.7

849234
type: LocalParameter
units: metaid_0000089
value: 0.018

849222
type: LocalParameter
units: metaid_0000089
value: 0.01

849210
type: LocalParameter
units: metaid_0000090
value: 1575.0

849126
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000027

849101
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000026

849138
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

metaid_0000072
type: Reaction
is version of: http://identifiers.org/ec-code/2.2.1.1
reactant: 849657
product: 849693
product: 849681
reactant: 849669
kinetic law: 849705
name: Transketolase 1
reversible: true
is: R01641
fast: false
is: REACT 1629

849657
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030

849693
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000032

849681
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000010

849669
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

849789
type: LocalParameter
units: dimensionless
value: 0.41139

849741
type: LocalParameter
units: metaid_0000089
value: 0.4177

849717
type: LocalParameter
units: metaid_0000090
value: 23.5

849801
type: LocalParameter
units: metaid_0000089
value: 0.00496

849777
type: LocalParameter
units: metaid_0000089
value: 12.432

849765
type: LocalParameter
units: dimensionless
value: 0.00774

849753
type: LocalParameter
units: metaid_0000089
value: 0.3055

849729
type: LocalParameter
units: dimensionless
value: 1.05

849813
type: LocalParameter
units: dimensionless
value: 48.8

metaid_0000088
type: SBMLUnitsDef
unit: 846787
name: hour

846787
type: SBMLUnit
exponent: 1.0
scale: 0
multipler: 3600.0
kind: SECOND

metaid_0000065
type: Reaction
reversible: true
name: Adenylate kinase
kinetic law: 848836
product: 848812
reactant: 848800
is: R00127
product: 848824
reactant: 848788
is version of: http://identifiers.org/ec-code/2.7.4.3
fast: false

848896
type: LocalParameter
units: metaid_0000089
value: 0.11

848884
type: LocalParameter
units: dimensionless
value: 0.25

848872
type: LocalParameter
units: metaid_0000089
value: 0.08

848860
type: LocalParameter
units: metaid_0000089
value: 0.09

848848
type: LocalParameter
units: metaid_0000090
value: 1380.0

848812
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000025

848800
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000024

848824
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000007

848788
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000005

metaid_0000052
type: Reaction
product: 847357
modifier: 847369
kinetic law: 847418
is: REACT 736
fast: false
modifier: 847381
name: Phosphofructokinase
is version of: http://identifiers.org/ec-code/2.7.1.11
reactant: 847333
is: R00756
reactant: 847321
modifier: 847393
reversible: true
product: 847345
modifier: 847406

847357
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000007

847514
type: LocalParameter
units: metaid_0000089
value: 0.033

847502
type: LocalParameter
units: metaid_0000089
value: 0.44

847490
type: LocalParameter
units: metaid_0000089
value: 0.01

847478
type: LocalParameter
units: dimensionless
value: 0.001072

847466
type: LocalParameter
units: metaid_0000089
value: 0.068

847454
type: LocalParameter
units: metaid_0000089
value: 0.1

847442
type: LocalParameter
units: dimensionless
value: 100000.0

847430
type: LocalParameter
units: metaid_0000090
value: 239.0

847333
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000008

847321
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000005

847345
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000009

metaid_0000040
type: Species
initial concentration: 0.024
initial amount: NaN
constant: false
in compartment: metaid_0000003
boundary condition: false
has part: CHEBI:36080
has part: C00017
name: Protein1 bound NADPH
has part: CHEBI:16474
has part: C00005
has only substance units: false

metaid_0000082
type: Reaction
kinetic law: 850705
product: 850693
product: 850681
reactant: 850669
fast: false
reversible: true
name: MgGri23P2 dissociation

850729
type: LocalParameter
units: metaid_0000089
value: 1.667

850717
type: LocalParameter
units: metaid_0000091
value: 1.0E7

850693
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000017

850681
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000036

850669
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000037

metaid_0000078
type: Reaction
kinetic law: 850417
product: 850405
reactant: 850393
is version of: GO:0009935
fast: false
reversible: true
name: Pyruvate exchange

850441
type: LocalParameter
units: dimensionless
value: 1.0

850429
type: LocalParameter
units: metaid_0000091
value: 10000.0

850405
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000020

850393
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000046

metaid_0000050
type: Reaction
modifier: 847079
modifier: 847067
is: REACT 1318
reversible: true
product: 847043
is: R00299
name: Hexokinase
modifier: 847055
kinetic law: 847091
is version of: http://identifiers.org/ec-code/2.7.1.2
reactant: 847007
product: 847031
reactant: 847019
fast: false

847043
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000007

847127
type: LocalParameter
units: metaid_0000090
value: 15.8

847212
type: LocalParameter
units: metaid_0000089
value: 2.7

847103
type: LocalParameter
units: dimensionless
value: 1.0

847139
type: LocalParameter
units: metaid_0000089
value: 1.44

847115
type: LocalParameter
units: metaid_0000089
value: 0.1

847188
type: LocalParameter
units: metaid_0000089
value: 1.03

847163
type: LocalParameter
units: metaid_0000089
value: 1.14

847200
type: LocalParameter
units: metaid_0000089
value: 0.0045

847151
type: LocalParameter
units: metaid_0000090
value: 33.2

847224
type: LocalParameter
units: metaid_0000089
value: 3.44

847176
type: LocalParameter
units: metaid_0000089
value: 3900.0

847007
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000004

847031
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000006

847019
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000005

metaid_0000059
type: Reaction
reversible: true
fast: false
product: 848230
reactant: 848218
name: Phosphoglycerate mutase
kinetic law: 848243
is version of: http://identifiers.org/ec-code/5.4.2.1
is: REACT 576
is: R01518

848230
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000018

metaid_0000018
type: Species
initial concentration: 0.0084
in compartment: metaid_0000003
constant: false
name: 2-Phospho-D-glycerate
boundary condition: false
initial amount: NaN
has only substance units: false
is: C00631
is: CHEBI:17835

848218
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000016

848293
type: LocalParameter
units: metaid_0000089
value: 1.0

848280
type: LocalParameter
units: metaid_0000089
value: 5.0

848268
type: LocalParameter
units: dimensionless
value: 0.145

848256
type: LocalParameter
units: metaid_0000090
value: 2000.0

metaid_0000080
type: Reaction
kinetic law: 850561
product: 850549
product: 850537
reactant: 850525
fast: false
reversible: true
name: MgADP dissociation

850585
type: LocalParameter
units: metaid_0000089
value: 0.76

850573
type: LocalParameter
units: metaid_0000091
value: 1.0E7

850549
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000025

850537
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000036

850525
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000007

metaid_0000076
type: Reaction
kinetic law: 850297
product: 850285
reactant: 850273
is version of: GO:0009935
fast: false
reversible: true
name: Phosphate exchange

850321
type: LocalParameter
units: dimensionless
value: 1.0

850309
type: LocalParameter
units: metaid_0000091
value: 100.0

850285
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000012

850273
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000048

metaid_0000048
type: Species
is: CHEBI:35780
constant: false
boundary condition: true
has only substance units: false
initial concentration: 1.0
initial amount: NaN
in compartment: metaid_0000003
name: Phosphate external

metaid_0000060
type: Reaction
is: R00658
reactant: 848305
reversible: true
kinetic law: 848329
name: Enolase
is: REACT 1400
product: 848317
is version of: http://identifiers.org/ec-code/4.2.1.11
fast: false

848305
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000018

848378
type: LocalParameter
units: metaid_0000089
value: 1.0

848366
type: LocalParameter
units: metaid_0000089
value: 1.0

848354
type: LocalParameter
units: dimensionless
value: 1.7

848342
type: LocalParameter
units: metaid_0000090
value: 1500.0

848317
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000019

metaid_0000069
type: Reaction
kinetic law: 849463
product: 849451
reactant: 849439
is: REACT 2037
is version of: http://identifiers.org/ec-code/1.8.1.7
fast: false
reversible: true
name: Glutathione oxidation

849476
type: LocalParameter
units: metaid_0000091
value: 0.03

849451
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000028

849439
type: SpeciesReference
stoichiometry: 2.0
species: metaid_0000029

metaid_0000056
type: Reaction
is version of: http://identifiers.org/ec-code/2.7.2.3
reactant: 847916
kinetic law: 847952
reactant: 847904
product: 847940
reversible: true
product: 847928
is: R01512
is: REACT 1186
name: Phosphoglycerate kinase
fast: false

847916
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000014

848025
type: LocalParameter
units: metaid_0000089
value: 1.2

848013
type: LocalParameter
units: metaid_0000089
value: 0.48

848000
type: LocalParameter
units: dimensionless
value: 1455.0

847988
type: LocalParameter
units: metaid_0000089
value: 0.002

847976
type: LocalParameter
units: metaid_0000089
value: 0.35

847964
type: LocalParameter
units: metaid_0000090
value: 5000.0

847904
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000007

847940
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000016

847928
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000005

ORG:
  orgname: Stellenbosh University
n:
  given: Jacky L
  family: Snoep

metaid_0000071
type: Reaction
reversible: true
is: R01056
name: Ribose phosphate isomerase
fast: false
product: 849584
is: http://identifiers.org/ec-code/5.3.1.6
is: REACT 2033
kinetic law: 849596
reactant: 849572

849584
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

849644
type: LocalParameter
units: metaid_0000089
value: 2.2

849632
type: LocalParameter
units: metaid_0000089
value: 0.78

849620
type: LocalParameter
units: dimensionless
value: 3.0

849608
type: LocalParameter
units: metaid_0000090
value: 730.0

849572
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000027

metaid_0000086
type: Reaction
kinetic law: 850993
product: 850981
product: 850969
reactant: 850957
is version of: GO:0006735
fast: false
reversible: true
name: P2NADPH dissociation

851017
type: LocalParameter
units: metaid_0000089
value: 2.0E-4

851005
type: LocalParameter
units: metaid_0000091
value: 1.0E7

850981
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

850969
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000042

850957
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000043

metaid_0000054
type: Reaction
is: REACT 775
name: Triosephosphate isomerase
is: R01015
is version of: http://identifiers.org/ec-code/5.3.1.1
fast: false
product: 847672
reactant: 847660
kinetic law: 847685
reversible: true

847672
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000010

847660
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000011

847733
type: LocalParameter
units: metaid_0000089
value: 0.428

847721
type: LocalParameter
units: metaid_0000089
value: 0.838

847709
type: LocalParameter
units: dimensionless
value: 0.0407

847697
type: LocalParameter
units: metaid_0000090
value: 5456.600098

metaid_0000084
type: Reaction
kinetic law: 850849
product: 850837
product: 850825
reactant: 850813
is version of: GO:0006740
fast: false
reversible: true
name: P1NADPH dissociation

850873
type: LocalParameter
units: metaid_0000089
value: 1.0E-5

850861
type: LocalParameter
units: metaid_0000091
value: 1.0E7

850837
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000022

850825
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000039

850813
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000040

metaid_0000081
type: Reaction
kinetic law: 850633
product: 850621
product: 850609
reactant: 850597
fast: false
reversible: true
name: MgAMP dissociation

850657
type: LocalParameter
units: metaid_0000089
value: 16.64

850645
type: LocalParameter
units: metaid_0000091
value: 1.0E7

850621
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000024

850609
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000036

850597
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000034

W3 CDTF: Wed May 16 11:20:02 BST 2012

metaid_0000064
type: Reaction
kinetic law: 848764
fast: false
reactant: 848728
is version of: http://identifiers.org/ec-code/3.6.1.3
is: R00086
name: ATPase
reversible: true
product: 848740
product: 848752

848776
type: LocalParameter
units: metaid_0000091
value: 1.68

848728
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000005

848740
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000012

848752
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000007

metaid_0000075
type: Reaction
is: REACT 1811
is version of: http://identifiers.org/ec-code/2.2.1.1
product: 850127
name: Transketolase 2
is: R01830
kinetic law: 850151
product: 850139
fast: false
reactant: 850103
reactant: 850115
reversible: true

850127
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000010

850188
type: LocalParameter
units: metaid_0000089
value: 0.00184

850224
type: LocalParameter
units: metaid_0000089
value: 0.0548

850200
type: LocalParameter
units: metaid_0000089
value: 0.3055

850237
type: LocalParameter
units: dimensionless
value: 0.0287

850212
type: LocalParameter
units: dimensionless
value: 0.122

850249
type: LocalParameter
units: metaid_0000089
value: 3.0E-4

850176
type: LocalParameter
units: dimensionless
value: 1.2

850261
type: LocalParameter
units: dimensionless
value: 0.215

850163
type: LocalParameter
units: metaid_0000090
value: 23.5

850139
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000008

850103
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030

850115
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000033

ORG:
  orgname: California Institute of Technology
n:
  given: Harish
  family: Dharuri

W3 CDTF: Thu Sep 07 16:04:38 BST 2006