BIOMD0000000066
type: SBMLModel
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units def: metaid_0000028
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reaction: metaid_0000018
compartment: metaid_0000003
reaction: metaid_0000019
area units: area
notes: . . . SBML level 2 code generated for the JWS Online project by Jacky Snoep using PySCeS Run this model online at http://jjj.biochem.sun.ac.za To cite JWS Online please refer to: Olivier, B.G. and Snoep, J.L. (2004) Web-based modelling using JWS Online , Bioinformatics, 20:2143-2144 . . . . . . Biomodels Curation: The model reproduces Fig 2f of the paper. The Vmax values for different reactions are obtained by multiplying the specific activites given in Table 3 of the paper with the protein concentration and an assay correction factor that was provided by the authors. The protein concentration is 202 mg/litre. The specific activities that need to be taken into consideration are those given for "variable threonine" in Table 3. The following are the assay correction factors provided by the authors: vak1=1.49; vak3=1.12; vasd=1.14; vhsd=1.42; vts=1.15; vhk=1.13. The model was successfully tested on MathSBML and Jarnac
species: metaid_0000008
species: metaid_0000010
units def: metaid_0000022
created:
  W3 CDTF: Tue Aug 29 11:11:33 BST 2006
species: metaid_0000011
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species: metaid_0000005
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reaction: metaid_0000017
occurs in: http://identifiers.org/taxonomy/83333
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is: MODEL6624131052
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creator:
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    orgname: Stellenbosh University
  n:
    given: Jacky L
    family: Snoep
substance units: metaid_0000022
name: Chassagnole2001_Threonine Synthesis
curated: true
volume units: metaid_0000323
has part: GO:0006531
length unit: length
creator:
  ORG:
    orgname: California Institute of Technology
  n:
    given: Harish
    family: Dharuri
reaction: metaid_0000021
units def: metaid_0000023
has part: GO:0009088
modified:
  W3 CDTF: Wed May 16 11:20:51 BST 2012
is version of: map00260
is described by: http://identifiers.org/pubmed/11368770
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name: O-Phospho-homoserine
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metaid_0000003
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reversible: true
name: Endogenous consumption of NADPH

800667
type: LocalParameter
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value: 202.0
name: Protein

800655
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value: 5.4E-6

metaid_0000026
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name: NADP
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metaid_0000012
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metaid_0000018
type: Reaction
name: Threonine synthase
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product: 800390
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reversible: true
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800402
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metaid_0000008
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name: Threonine
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800438
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value: 0.31

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800426
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metaid_0000025
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800378
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metaid_0000019
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metaid_0000013
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800474
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800462
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metaid_0000014
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name: ATP
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800450
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metaid_0000006
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800607
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value: 4.35

800595
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value: 1.09

800582
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value: 0.11

800570
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value: 4.7

800558
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800546
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800534
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800522
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value: 0.1

metaid_0000010
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name: Aspartate
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metaid_0000022
type: SBMLUnitsDef
unit: 799569
name: millimole

799569
type: SBMLUnit
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scale: -3
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kind: MOLE

metaid_0000005
type: Species
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metaid_0000016
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name: Aspartate semialdehyde dehydrogenase

800028
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800052
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800076
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800149
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800137
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800125
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value: 56.4150334574039

800100
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800040
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name: Aspartyl phosphate

metaid_0000017
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name: Homoserine dehydrogenase
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800209
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800221
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800185
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800294
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800306
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800342
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800330
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800366
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800269
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800354
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800281
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value: 3162.27766016838

metaid_0000023
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799581
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metaid_0000015
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is version of: GO:0004072
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is: R00480
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is version of: http://identifiers.org/ec-code/2.7.2.4
kinetic law: 799811
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799883
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value: 4.09

800004
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value: 2.8

799859
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value: 0.167

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value: 0.46

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value: 0.98

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value: 6.4E-4

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value: 0.15

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value: 0.32

metaid_0000027
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metaid_0000021
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is: GO:0016887
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reversible: true
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800740
type: LocalParameter
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value: 202.0
name: Protein

800728
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units: metaid_0000027
value: 4.1E-5

800704
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800692
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