BIOMD0000000057
type: SBMLModel
parameter: metaid_0000051
time units: metaid_0000366
area units: area
reaction: metaid_0000045
reaction: metaid_0000041
is: MODEL9098147664
parameter: metaid_0000018
reaction: metaid_0000044
species: metaid_0000032
parameter: metaid_0000022
units def: metaid_0000047
parameter: metaid_0000005
parameter: metaid_0000013
curated: true
rule: metaid_0000035
parameter: metaid_0000008
parameter: metaid_0000016
rule: metaid_0000034
parameter: metaid_0000012
parameter: metaid_0000020
parameter: metaid_0000003
is version of: GO:0019722
is version of: GO:0006816
parameter: metaid_0000048
parameter: metaid_0000009
created:
  W3 CDTF: Tue May 30 13:07:25 BST 2006
species: metaid_0000027
species: metaid_0000028
reaction: metaid_0000042
species: metaid_0000030
species: metaid_0000031
parameter: metaid_0000019
name: Sneyd2002_IP3_Receptor
is: map04020
parameter: metaid_0000049
parameter: metaid_0000023
rule: metaid_0000040
parameter: metaid_0000006
creator:
  ORG:
    orgname: California Institute of Technology
  n:
    given: Harish
    family: Dharuri
parameter: metaid_0000014
parameter: metaid_0000010
notes: This model was successfully tested on Jarnac and MathSBML. The model reproduces the time profile of "Open Probability" of the receptor as shown in Figure 4 of the publication. The value of calcium ion concentration "c" in this model is 10 microM. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
is version of: GO:0005220
rule: metaid_0000033
rule: metaid_0000039
is version of: GO:0048016
parameter: metaid_0000004
is version of: GO:0031585
parameter: metaid_0000024
is described by: http://identifiers.org/pubmed/11842185
rule: metaid_0000038
parameter: metaid_0000050
occurs in: http://identifiers.org/taxonomy/10117
length unit: length
species: metaid_0000029
parameter: metaid_0000017
parameter: metaid_0000025
parameter: metaid_0000021
reaction: metaid_0000043
rule: metaid_0000036
substance units: metaid_0000047
modified:
  W3 CDTF: Thu Jul 05 17:30:21 BST 2012
parameter: metaid_0000007
parameter: metaid_0000015
parameter: metaid_0000011
volume units: metaid_0000323
compartment: metaid_0000026
rule: metaid_0000037

metaid_0000051
type: Parameter
constant: true
value: 29.8

metaid_0000045
type: Reaction
kinetic law: 213872
product: 213860
reactant: 213848
is version of: GO:0031586
fast: false
reversible: true
name: Activated-Inactivated state 2 transition

213896
type: LocalParameter
value: 0.8

213884
type: LocalParameter
value: 0.04

213860
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000032

metaid_0000032
type: Species
is version of: IPR000493
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000026
name: Inactivated State 2

metaid_0000026
type: Compartment
is: GO:0005829
constant: true
size: 1.0
spatial dimensions: 3.0

213848
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

metaid_0000031
type: Species
is version of: IPR000493
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000026
name: Activated State

metaid_0000041
type: Reaction
kinetic law: 213680
product: 213668
reactant: 213656
is version of: GO:0005220
is version of: GO:0031587
fast: false
reversible: true
name: Receptor-Open state transition

213692
type: LocalParameter
value: 10.0

213668
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000028

metaid_0000028
type: Species
is version of: IPR000493
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000026
name: Open State

213656
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000027

metaid_0000027
type: Species
is version of: IPR000493
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.0
initial amount: NaN
in compartment: metaid_0000026
name: Receptor

metaid_0000018
type: Parameter
constant: true
value: 0.11

metaid_0000044
type: Reaction
kinetic law: 213836
product: 213824
reactant: 213812
is version of: GO:0031587
fast: false
reversible: true
name: Open-Activated state transition

213824
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000031

213812
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000028

metaid_0000022
type: Parameter
constant: false
value: 0.0

metaid_0000047
type: SBMLUnitsDef
unit: 213644
name: micromole

213644
type: SBMLUnit
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE

metaid_0000005
type: Parameter
constant: true
value: 0.64

metaid_0000013
type: Parameter
constant: false
value: 0.0

metaid_0000008
type: Parameter
constant: true
value: 10.0

metaid_0000016
type: Parameter
constant: true
value: 54.7

metaid_0000012
type: Parameter
constant: true
value: 1.7

metaid_0000020
type: Parameter
constant: true
value: 4.0

metaid_0000003
type: Parameter
constant: false
value: 0.0

metaid_0000048
type: Parameter
constant: true
value: 10.0
name: IP3

metaid_0000009
type: Parameter
constant: true
value: 0.025

metaid_0000042
type: Reaction
kinetic law: 213728
product: 213716
reactant: 213704
is version of: GO:0031586
fast: false
reversible: true
name: Receptor-Inactivated state 1 transition

213752
type: LocalParameter
value: 0.8

213740
type: LocalParameter
value: 0.04

213716
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000029

metaid_0000029
type: Species
is version of: IPR000493
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000026
name: Inactivated State 1

213704
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000027

metaid_0000030
type: Species
is version of: IPR000493
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000026
name: Shut State

metaid_0000019
type: Parameter
constant: false
value: 0.0

metaid_0000049
type: Parameter
constant: true
value: 0.8

metaid_0000023
type: Parameter
constant: true
value: 0.54

metaid_0000006
type: Parameter
constant: true
value: 0.12

metaid_0000014
type: Parameter
constant: true
value: 1.4

metaid_0000010
type: Parameter
constant: false
value: 0.0

metaid_0000004
type: Parameter
constant: false
value: 0.0

metaid_0000024
type: Parameter
constant: true
value: 11.4

metaid_0000050
type: Parameter
constant: true
value: 0.04

metaid_0000017
type: Parameter
constant: false
value: 0.0

metaid_0000025
type: Parameter
constant: false
value: 0.0

metaid_0000021
type: Parameter
constant: true
value: 4707.0

metaid_0000043
type: Reaction
kinetic law: 213788
product: 213776
reactant: 213764
is version of: GO:0031586
fast: false
reversible: true
name: Open-Shut state transition

213800
type: LocalParameter
value: 29.8

213776
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000030

213764
type: SpeciesReference
stoichiometry: 1.0
species: metaid_0000028

metaid_0000007
type: Parameter
constant: true
value: 1.7

metaid_0000015
type: Parameter
constant: true
value: 2.5

metaid_0000011
type: Parameter
constant: true
value: 37.4