UnificationXref3539
type: UnificationXref
id: 5593683
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593683

PublicationXref1075
type: PublicationXref
author: Oesch, F
author: Arand, M
title: Toxicology
source: 83-107
year: 1999

UnificationXref3536
type: UnificationXref
id: PF10_0103
db: UniProt

UnificationXref3535
type: UnificationXref
id: 5593677
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593677

UnificationXref3538
type: UnificationXref
id: 5593682
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593682

UnificationXref3537
type: UnificationXref
id: 5593679
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593679

UnificationXref3532
type: UnificationXref
id: PF14_0104
db: UniProt

UnificationXref3531
type: UnificationXref
id: 5593673
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593673

UnificationXref3534
type: UnificationXref
id: PF07_0117
db: UniProt

UnificationXref3533
type: UnificationXref
id: 5593681
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593681

UnificationXref2088
type: UnificationXref
id: 2162209
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2162209

UnificationXref2089
type: UnificationXref
id: REACT_160379
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_160379.1

UnificationXref2086
type: UnificationXref
id: REACT_160998
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_160998.1

UnificationXref3530
type: UnificationXref
id: 5593668
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593668

UnificationXref2087
type: UnificationXref
id: CHEBI:50775
db: ChEBI

UnificationXref2085
type: UnificationXref
id: 2162265
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2162265

UnificationXref2084
type: UnificationXref
id: CHEBI:15414
db: ChEBI

UnificationXref2083
type: UnificationXref
id: REACT_210311
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_210311.2

UnificationXref2082
type: UnificationXref
id: 5596310
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596310

UnificationXref2081
type: UnificationXref
id: 5596308
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596308

UnificationXref2080
type: UnificationXref
id: PFF0370w
db: UniProt

UnificationXref3529
type: UnificationXref
id: PF10_0077
db: UniProt

UnificationXref3528
type: UnificationXref
id: 5593670
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593670

UnificationXref3527
type: UnificationXref
id: PFL0310c
db: UniProt

UnificationXref3526
type: UnificationXref
id: 5593658
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593658

UnificationXref3525
type: UnificationXref
id: MAL7P1.81
db: UniProt

UnificationXref3524
type: UnificationXref
id: 5593660
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593660

UnificationXref2079
type: UnificationXref
id: REACT_160757
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_160757.1

UnificationXref3523
type: UnificationXref
id: MAL8P1.83
db: UniProt

http://identifiers.org/pubmed/11903050
type: PublicationXref
id: 11903050
author: MacMullen, CM
author: Smith, TJ
author: Poncz, M
author: Hsu, BY
author: Fang, J
author: Stanley, CA
db: Pubmed
title: Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations
source: Biochem J 363:81-7
year: 2002

http://identifiers.org/pubmed/9809442
type: PublicationXref
id: 9809442
author: Marin-Garcia, J
author: Ananthakrishnan, R
author: Goldenthal, MJ
db: Pubmed
title: Cloning and molecular analysis of the human citrate synthase gene
source: Genome 41:733-738
year: 1998

UnificationXref3522
type: UnificationXref
id: 5593662
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593662

UnificationXref3521
type: UnificationXref
id: PFI0895c
db: UniProt

UnificationXref3520
type: UnificationXref
id: 5593672
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593672

UnificationXref2075
type: UnificationXref
id: 2162214
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2162214

UnificationXref2076
type: UnificationXref
id: REACT_161199
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_161199.1

UnificationXref2077
type: UnificationXref
id: CHEBI:64136
db: ChEBI

UnificationXref2078
type: UnificationXref
id: 2162207
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2162207

UnificationXref2072
type: UnificationXref
id: 2162213
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2162213

UnificationXref2071
type: UnificationXref
id: CHEBI:30763
db: ChEBI

UnificationXref2074
type: UnificationXref
id: CHEBI:61011
db: ChEBI

UnificationXref2073
type: UnificationXref
id: REACT_160368
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_160368.1

http://identifiers.org/pubmed/9478990
type: PublicationXref
id: 9478990
author: Kadowaki, T
author: Ueki, K
author: Komuro, I
author: Kaburagi, Y
author: Akanuma, Y
author: Burgering, B M
author: Yazaki, Y
author: Coffer, P J
author: Yamamoto-Honda, R
author: Tobe, K
author: Yamauchi, T
db: Pubmed
title: Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis
source: J. Biol. Chem. 273:5315-22
year: 1998

UnificationXref2070
type: UnificationXref
id: REACT_242772
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_242772.1

UniProt:MAL13P1.167
type: ProteinReference
xref: UnificationXref4783
organism: http://identifiers.org/taxonomy/5833

UnificationXref3514
type: UnificationXref
id: 5593656
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593656

UnificationXref3513
type: UnificationXref
id: 5593611
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593611

UnificationXref3516
type: UnificationXref
id: 5593666
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593666

UnificationXref3515
type: UnificationXref
id: PFL0625c
db: UniProt

UnificationXref3518
type: UnificationXref
id: 5593664
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593664

http://identifiers.org/pubmed/16322778
type: PublicationXref
id: 16322778
author: Kaushansky, K
db: Pubmed
title: The molecular mechanisms that control thrombopoiesis
source: J Clin Invest 115:3339-47
year: 2005

UnificationXref3517
type: UnificationXref
id: PFE0885w
db: UniProt

UnificationXref3519
type: UnificationXref
id: PFE1405c
db: UniProt

UnificationXref2066
type: UnificationXref
id: REACT_230345
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_230345.1

UnificationXref2067
type: UnificationXref
id: 5596978
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596978

UnificationXref2064
type: UnificationXref
id: 5595342
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595342

UnificationXref2065
type: UnificationXref
id: 5595344
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595344

UnificationXref3510
type: UnificationXref
id: PF14_0585
db: UniProt

UnificationXref2068
type: UnificationXref
id: REACT_192074
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192074.3

UnificationXref3512
type: UnificationXref
id: PFL2055w
db: UniProt

UnificationXref2069
type: UnificationXref
id: 5596979
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596979

UnificationXref3511
type: UnificationXref
id: 5593633
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593633

http://identifiers.org/pubmed/18442489
type: PublicationXref
id: 18442489
author: Wallace, JC
author: Pendini, Nicole R
author: Wilce, Matthew C
author: Polyak, Steven W
author: Booker, Grant W
author: Bailey, Lisa M
db: Pubmed
title: Microbial biotin protein ligases aid in understanding holocarboxylase synthetase deficiency
source: Biochim. Biophys. Acta 1784:973-82
year: 2008

UnificationXref2063
type: UnificationXref
id: 5595341
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595341

UnificationXref2062
type: UnificationXref
id: 5595340
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595340

UnificationXref2061
type: UnificationXref
id: 5595339
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595339

UnificationXref2060
type: UnificationXref
id: 5595338
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595338

http://identifiers.org/pubmed/642006
type: PublicationXref
id: 642006
author: Gall, JG
author: Blackburn, EH
db: Pubmed
title: A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena
source: J Mol Biol 120:33-53
year: 1978

UnificationXref3505
type: UnificationXref
id: 5593637
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593637

UnificationXref3504
type: UnificationXref
id: PF14_0627
db: UniProt

UnificationXref3503
type: UnificationXref
id: 5593619
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593619

http://identifiers.org/pubmed/17986282
type: PublicationXref
id: 17986282
author: Uemura, M
author: Nakagawa, H
author: Nakamura, Y
author: Chung, S
author: Tamura, K
author: Honma, S
author: Okuyama, A
db: Pubmed
title: Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer
source: Cancer Sci 99:81-6
year: 2008

UnificationXref3502
type: UnificationXref
id: PF14_0448
db: UniProt

UnificationXref3509
type: UnificationXref
id: 5593631
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593631

UnificationXref3508
type: UnificationXref
id: PF13_0045
db: UniProt

UnificationXref3507
type: UnificationXref
id: 5593655
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593655

UnificationXref3506
type: UnificationXref
id: PF10_0264
db: UniProt

UnificationXref2053
type: UnificationXref
id: REACT_20160
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_20160.2

http://identifiers.org/pubmed/18786386
type: PublicationXref
id: 18786386
author: Maywood, ES
author: O'Neill, JS
author: Hastings, MH
db: Pubmed
title: Cellular circadian pacemaking and the role of cytosolic rhythms
source: Curr Biol 18:R805-R815
year: 2008

UnificationXref2054
type: UnificationXref
id: CHEBI:31488
db: ChEBI

UnificationXref2055
type: UnificationXref
id: 428126
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=428126

UnificationXref2056
type: UnificationXref
id: REACT_19455
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_19455.2

UniProt:MAL13P1.190
type: ProteinReference
xref: UnificationXref3724
organism: http://identifiers.org/taxonomy/5833

UnificationXref2057
type: UnificationXref
id: PF14_0034
db: UniProt

UnificationXref3501
type: UnificationXref
id: 5593653
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593653

UnificationXref2058
type: UnificationXref
id: 5595336
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595336

UnificationXref3500
type: UnificationXref
id: PFE1005w
db: UniProt

UnificationXref2059
type: UnificationXref
id: 5595337
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595337

PublicationXref1080
type: PublicationXref
author: Parkinson, A
title: Casarett and Doull's Toxicology 5th Edn
source: 113-186
year: 1995

UnificationXref2050
type: UnificationXref
id: REACT_177495
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_177495.3

UnificationXref2052
type: UnificationXref
id: 428163
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=428163

UnificationXref2051
type: UnificationXref
id: CHEBI:16566
db: ChEBI

Methionine salvage pathway
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction268
evidence: Evidence461
xref: RelationshipXref465
xref: UnificationXref2912
xref: UnificationXref2911
pathway order: PathwayStep457
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UniProt:MAL13P1.189
type: ProteinReference
xref: UnificationXref1045
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/11158296
type: PublicationXref
id: 11158296
author: Pelzer, W
author: Kmita, H
author: Diekert, K
author: Bedekovics, T
author: Lill, R
author: Prohl, C
author: Kispal, G
db: Pubmed
title: The yeast mitochondrial carrier Leu5p and its human homologue Graves' disease protein are required for accumulation of coenzyme A in the matrix
source: Mol Cell Biol 21:1089-97
year: 2001

UnificationXref2049
type: UnificationXref
id: 5595334
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595334

UnificationXref3575
type: UnificationXref
id: 5593126
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593126

UnificationXref2048
type: UnificationXref
id: 5595332
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595332

UnificationXref3576
type: UnificationXref
id: 5593129
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593129

UnificationXref2047
type: UnificationXref
id: 5595331
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595331

UnificationXref3577
type: UnificationXref
id: 68419
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=68419

UnificationXref2046
type: UnificationXref
id: 5595330
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595330

UnificationXref3578
type: UnificationXref
id: REACT_3087
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3087.1

UnificationXref2045
type: UnificationXref
id: 5595328
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595328

UnificationXref3571
type: UnificationXref
id: PF14_0366
db: UniProt

UnificationXref2044
type: UnificationXref
id: 5595325
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595325

UnificationXref3572
type: UnificationXref
id: 5593128
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593128

UnificationXref2043
type: UnificationXref
id: 5595327
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595327

UnificationXref3573
type: UnificationXref
id: PF14_0602
db: UniProt

UnificationXref2042
type: UnificationXref
id: PF14_0155
db: UniProt

UnificationXref3574
type: UnificationXref
id: 5593125
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593125

http://identifiers.org/pubmed/23222971
type: PublicationXref
id: 23222971
author: Lu, Ning
author: Yuan, Bin
author: Zhang, Zhiqiang
author: Bao, Musheng
author: Liu, Yong-Jun
author: Weng, Leiyun
db: Pubmed
title: The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA
source: Nat. Immunol.
year: 2012

UnificationXref3579
type: UnificationXref
id: PFF1470c
db: UniProt

http://identifiers.org/pubmed/17697045
type: PublicationXref
id: 17697045
author: Mikoshiba, K
db: Pubmed
title: IP3 receptor/Ca2+ channel: from discovery to new signaling concepts
source: J Neurochem 102:1426-46
year: 2007

UnificationXref2040
type: UnificationXref
id: 428182
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=428182

UnificationXref2041
type: UnificationXref
id: REACT_20257
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_20257.1

UnificationXref3570
type: UnificationXref
id: REACT_192655
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192655.3

UnificationXref2036
type: UnificationXref
id: REACT_193044
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_193044.3

UnificationXref3566
type: UnificationXref
id: 5595613
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595613

UnificationXref4299
type: UnificationXref
id: 5596618
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596618

UnificationXref2035
type: UnificationXref
id: 5597089
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597089

UnificationXref3567
type: UnificationXref
id: 5595614
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595614

UnificationXref4298
type: UnificationXref
id: 5596597
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596597

UnificationXref2038
type: UnificationXref
id: REACT_192114
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192114.3

UnificationXref3564
type: UnificationXref
id: 5593120
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593120

UnificationXref4297
type: UnificationXref
id: 5596596
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596596

UnificationXref2037
type: UnificationXref
id: 5596948
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596948

UnificationXref3565
type: UnificationXref
id: 5595612
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595612

UnificationXref2032
type: UnificationXref
id: REACT_150517
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_150517.1

UnificationXref3562
type: UnificationXref
id: PFD0590c
db: UniProt

UnificationXref2031
type: UnificationXref
id: 2142678
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2142678

UnificationXref3563
type: UnificationXref
id: 5593123
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593123

UnificationXref2034
type: UnificationXref
id: REACT_202674
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_202674.2

UnificationXref3560
type: UnificationXref
id: 5593298
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593298

UnificationXref2033
type: UnificationXref
id: 5596298
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596298

UnificationXref3561
type: UnificationXref
id: 5593299
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593299

http://identifiers.org/pubmed/11815450
type: PublicationXref
id: 11815450
author: Südhof, TC
author: Gerber, SH
db: Pubmed
title: Molecular determinants of regulated exocytosis
source: Diabetes 51:S3-11
year: 2002

PublicationXref1020
type: PublicationXref
id: 0079130356
author: Horwich, AL
author: Brusilow, SW
db: ISBN
title: Urea cycle enzymes
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 1909-1963
year: 2001

UniProt:PFB0535w
type: ProteinReference
xref: UnificationXref229
organism: http://identifiers.org/taxonomy/5833

UnificationXref2039
type: UnificationXref
id: CHEBI:17862
db: ChEBI

UnificationXref3568
type: UnificationXref
id: REACT_209098
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_209098.2

UnificationXref3569
type: UnificationXref
id: 5597009
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597009

http://identifiers.org/pubmed/9188485
type: PublicationXref
id: 9188485
author: Folk, JE
author: Park, MH
author: Wolff, EC
db: Pubmed
title: Enzyme-substrate intermediate formation at lysine 329 of human deoxyhypusine synthase
source: J Biol Chem 272:15865-71
year: 1997

UnificationXref4291
type: UnificationXref
id: PFE0270c
db: UniProt

UnificationXref4292
type: UnificationXref
id: 5596595
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596595

http://identifiers.org/pubmed/19962665
type: PublicationXref
id: 19962665
author: Yue, Peng
author: Eby, Michael
author: Stern, Howard M
author: Wang, Weiru
author: de Sauvage, Frederic J
author: Waring, Paul
author: Seshagiri, Somasekar
author: Kan, Zhengyan
author: Bowman, Krista K
author: Modrusan, Zora
author: Dela Vega, Trisha
author: Kenski, Denise M
author: Backer, Jonathan M
author: Chaudhuri, Subhra
author: Kaminker, Josh S
author: Kljavin, Noelyn M
author: Jaiswal, Bijay S
author: Stinson, Jeremy
author: Wu, Jiansheng
author: Peters, Brock A
author: Lorenzo, Maria
author: Janakiraman, Vasantharajan
author: Li, Hong
author: Dbouk, Hashem A
db: Pubmed
title: Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation
source: Cancer Cell 16:463-74
year: 2009

UnificationXref4290
type: UnificationXref
id: 5596593
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596593

UnificationXref2030
type: UnificationXref
id: CHEBI:34146
db: ChEBI

UnificationXref4295
type: UnificationXref
id: 5596610
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596610

UnificationXref4296
type: UnificationXref
id: REACT_246640
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_246640.1

UnificationXref4293
type: UnificationXref
id: 5596608
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596608

UnificationXref4294
type: UnificationXref
id: 5596609
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596609

UnificationXref2023
type: UnificationXref
id: 2142716
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2142716

UnificationXref2022
type: UnificationXref
id: CHEBI:34144
db: ChEBI

UnificationXref3550
type: UnificationXref
id: 5596855
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596855

UnificationXref2021
type: UnificationXref
id: REACT_151674
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_151674.1

UnificationXref3551
type: UnificationXref
id: REACT_244939
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_244939.1

UnificationXref2020
type: UnificationXref
id: 2142790
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2142790

UnificationXref3552
type: UnificationXref
id: MAL13P1.279
db: UniProt

UnificationXref4287
type: UnificationXref
id: 5596590
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596590

UnificationXref2027
type: UnificationXref
id: CHEBI:15626
db: ChEBI

UnificationXref3553
type: UnificationXref
id: 5595610
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595610

UnificationXref4286
type: UnificationXref
id: MAL7P1.206
db: UniProt

UnificationXref2026
type: UnificationXref
id: REACT_217427
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_217427.2

UnificationXref3554
type: UnificationXref
id: 5595611
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595611

UnificationXref4289
type: UnificationXref
id: 5596592
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596592

UnificationXref2025
type: UnificationXref
id: 5596295
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596295

UnificationXref3555
type: UnificationXref
id: PFL0150w
db: UniProt

UnificationXref4288
type: UnificationXref
id: PF14_0254
db: UniProt

UnificationXref2024
type: UnificationXref
id: REACT_152057
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_152057.1

UnificationXref3556
type: UnificationXref
id: 5593161
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593161

UnificationXref3557
type: UnificationXref
id: PFL1285c
db: UniProt

http://identifiers.org/pubmed/22240719
type: PublicationXref
id: 22240719
author: Jaeken, J
author: Ezgü, F S
author: Hasano?lu, A
author: Tümer, L
author: Matthijs, G
author: Race, V
author: Kasapkara, C S
db: Pubmed
title: SRD5A3-CDG: a patient with a novel mutation
source: Eur. J. Paediatr. Neurol. 16:554-6
year: 2012

http://identifiers.org/pubmed/12883891
type: PublicationXref
id: 12883891
author: Koepsell, H
author: Endou, H
db: Pubmed
title: The SLC22 drug transporter family
source: Pflugers Arch 447:666-76
year: 2004

UnificationXref3558
type: UnificationXref
id: 5593296
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593296

UnificationXref2029
type: UnificationXref
id: REACT_151618
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_151618.1

UnificationXref3559
type: UnificationXref
id: PF13_0328
db: UniProt

UnificationXref2028
type: UnificationXref
id: 2142811
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2142811

UniProt:PFF1095w
type: ProteinReference
xref: UnificationXref5479
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/10753883
type: PublicationXref
id: 10753883
author: Fukami, K
author: Funaki, M
author: Asano, T
author: Mochizuki, Y
author: Ijuin, T
author: Takenawa, T
db: Pubmed
title: Identification and characterization of a novel inositol polyphosphate 5-phosphatase
source: J Biol Chem 275:10870-5
year: 2000

UnificationXref4282
type: UnificationXref
id: 5596771
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596771

UnificationXref4283
type: UnificationXref
id: REACT_237118
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_237118.1

UnificationXref4284
type: UnificationXref
id: 5358514
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5358514

UnificationXref4285
type: UnificationXref
id: REACT_228358
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_228358.1

UnificationXref4280
type: UnificationXref
id: 5596828
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596828

http://identifiers.org/pubmed/8541526
type: PublicationXref
id: 8541526
author: Park, JG
author: Hunter, S
author: Schreiber, AD
author: Indik, ZK
db: Pubmed
title: The molecular dissection of Fc gamma receptor mediated phagocytosis
source: Blood 86:4389-99
year: 1995

UnificationXref4281
type: UnificationXref
id: REACT_237364
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_237364.1

Catalysis1
type: Catalysis
data source: Provenance1
controlled: ABC7, mABC1 and mABC2 mediate heme transport
control type: ACTIVATION
xref: RelationshipXref1
xref: RelationshipXref2
controller: Complex1

UnificationXref2010
type: UnificationXref
id: 2142733
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2142733

UnificationXref3540
type: UnificationXref
id: 72393
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=72393

UniProt:PF11_0524
type: ProteinReference
xref: UnificationXref3959
organism: http://identifiers.org/taxonomy/5833

Catalysis2
type: Catalysis
data source: Provenance1
controlled: MTABC3 transports porphyrin into mitochondria
control type: ACTIVATION
xref: RelationshipXref3
xref: RelationshipXref1
controller: Complex3

UnificationXref3541
type: UnificationXref
id: REACT_4829
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4829.1

Catalysis3
type: Catalysis
data source: Provenance1
controlled: Type III Na+/Pi cotransport
control type: ACTIVATION
xref: RelationshipXref5
xref: RelationshipXref6
controller: Protein3

UnificationXref2012
type: UnificationXref
id: PFL0595c
db: UniProt

UnificationXref4279
type: UnificationXref
id: REACT_231725
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_231725.1

Catalysis4
type: Catalysis
data source: Provenance1
controlled: alpha-D-Glucose + ATP => alpha-D-glucose 6-phosphate + ADP
control type: ACTIVATION
xref: RelationshipXref9
xref: RelationshipXref8
controller: Protein6

UnificationXref2011
type: UnificationXref
id: REACT_151106
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_151106.1

UnificationXref4278
type: UnificationXref
id: 5594192
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594192

Catalysis5
type: Catalysis
data source: Provenance1
controlled: Glucose transport by class III GLUTs
control type: ACTIVATION
xref: RelationshipXref13
xref: RelationshipXref14
controller: Protein11

UnificationXref2014
type: UnificationXref
id: 5596292
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596292

UnificationXref3544
type: UnificationXref
id: 5594374
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594374

UnificationXref4277
type: UnificationXref
id: 5594191
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594191

Catalysis6
type: Catalysis
data source: Provenance1
controlled: HMIT co-transports myo-inositol with a proton
control type: ACTIVATION
xref: RelationshipXref16
xref: RelationshipXref15
controller: Protein14

UnificationXref2013
type: UnificationXref
id: 5596291
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596291

UnificationXref3545
type: UnificationXref
id: 5594375
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594375

UnificationXref4276
type: UnificationXref
id: 5594190
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594190

Catalysis7
type: Catalysis
data source: Provenance1
controlled: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages
control type: ACTIVATION
xref: RelationshipXref17
xref: RelationshipXref18
controller: Protein15

UnificationXref2016
type: UnificationXref
id: REACT_222451
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_222451.2

UnificationXref3542
type: UnificationXref
id: 5593684
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593684

UnificationXref4275
type: UnificationXref
id: REACT_236266
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_236266.1

Catalysis8
type: Catalysis
data source: Provenance1
controlled: DCT1 (NRAMP2) mediates divalent iron uptake across the apical membrane of enterocytes
control type: ACTIVATION
xref: RelationshipXref19
xref: RelationshipXref20
controller: Protein16

UnificationXref2015
type: UnificationXref
id: 5596294
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596294

UnificationXref3543
type: UnificationXref
id: 5593685
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593685

UnificationXref2018
type: UnificationXref
id: REACT_193043
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_193043.3

UnificationXref3548
type: UnificationXref
id: 5596854
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596854

UnificationXref2017
type: UnificationXref
id: 5597088
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597088

UnificationXref3549
type: UnificationXref
id: REACT_234678
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_234678.1

UnificationXref3546
type: UnificationXref
id: 5594376
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594376

http://identifiers.org/pubmed/9771708
type: PublicationXref
id: 9771708
author: Ahmad, W
author: Swank, RT
author: Krakow, D
author: King, LM
author: Cohn, DH
author: Abbas, H
author: Ahmad, M
author: Rusiniak, ME
author: Superti-Furga, A
author: Cantor, RM
author: ul Haque, MF
author: Haque, S
db: Pubmed
title: Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse
source: Nat Genet 20:157-62
year: 1998

UnificationXref2019
type: UnificationXref
id: CHEBI:34145
db: ChEBI

UnificationXref3547
type: UnificationXref
id: REACT_244578
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_244578.1

http://identifiers.org/pubmed/11395502
type: PublicationXref
id: 11395502
author: Dutta, A
author: Delmolino, L
author: Dhar, SK
db: Pubmed
title: Architecture of the human origin recognition complex.
source: J Biol Chem 276:29067-71
year: 2001

Role of second messengers in netrin-1 signaling
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction335
evidence: Evidence619
xref: UnificationXref3921
xref: UnificationXref3920
pathway order: PathwayStep605
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4273
type: UnificationXref
id: REACT_237150
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_237150.1

UnificationXref4274
type: UnificationXref
id: 5596829
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596829

UnificationXref4271
type: UnificationXref
id: REACT_5433
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5433.1

UnificationXref4272
type: UnificationXref
id: 5594189
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594189

http://identifiers.org/pubmed/9771710
type: PublicationXref
id: 9771710
author: Snead, O Carter
author: Andermann, Eva
author: Dunham, Ian
author: Fong, Chung-yan G
author: Soder, Sylvia
author: Tsui, LC
author: Satishchandra, P
author: Scherer, Stephen W
author: Jardim, L
author: Huizenga, Jack
author: Delgado-Escueta, Antonio V
author: Gardner, Rebecca
author: Lopes-Cendes, Iscia
author: Lee, Jeffrey R
author: Minassian, Berge A
author: Mungall, Andrew J
author: Herbrick, Jo-Anne
author: Rouleau, Guy A
author: Carpenter, Stirling
db: Pubmed
title: Mutations in a gene encoding a novel protein tyrosine phosphatase cause progressive myoclonus epilepsy
source: Nat. Genet. 20:171-4
year: 1998

UnificationXref4270
type: UnificationXref
id: 110295
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=110295

Lagging Strand Synthesis
type: Pathway
data source: Provenance1
pathway component: REACT 249314.1
pathway component: REACT 234532.1
evidence: Evidence582
xref: UnificationXref3819
xref: UnificationXref3818
pathway order: PathwayStep571
pathway order: PathwayStep568
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

Formic acid
type: SmallMoleculeReference
name: Formate
name: Formate [ChEBI:30751]
name: Methanoic acid
xref: UnificationXref2188

Passive transport by Aquaporins
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction20
pathway component: BiochemicalReaction22
pathway component: BiochemicalReaction21
pathway component: BiochemicalReaction19
pathway component: BiochemicalReaction18
pathway component: BiochemicalReaction17
evidence: Evidence41
xref: UnificationXref275
xref: RelationshipXref39
xref: UnificationXref274
pathway order: PathwayStep35
pathway order: PathwayStep36
pathway order: PathwayStep37
pathway order: PathwayStep38
pathway order: PathwayStep39
pathway order: PathwayStep40
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

Catalysis9
type: Catalysis
data source: Provenance1
controlled: BiochemicalReaction10
control type: ACTIVATION
xref: RelationshipXref21
xref: RelationshipXref22
controller: Protein17

IDH2 dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry295
component stoichiometry: Stoichiometry294
component: Protein284
component: SmallMolecule339
xref: UnificationXref2282
cellular location: GO_0005759
comment: Reactome DB_ID: 5595538

Citrate Synthase Holoenzyme (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry293
component: Protein283
xref: UnificationXref2268
cellular location: GO_0005759
comment: Reactome DB_ID: 5593486

cyclopropylamine
type: SmallMoleculeReference
name: cyclopropylamine [ChEBI:34660]
name: Aminocyclopropane
xref: UnificationXref3154

NNT dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry296
component: Protein285
xref: UnificationXref2287
cellular location: GO_0005743
comment: Reactome DB_ID: 5595533

pyruvate dehydrogenase E1 complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry284
component stoichiometry: Stoichiometry283
component stoichiometry: Stoichiometry282
component: SmallMolecule334
component: Protein278
component: Protein279
xref: UnificationXref2249
cellular location: GO_0005759
comment: Reactome DB_ID: 5593537

alpha-keto acid dehydrogenase E3 homodimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry289
component: alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens)
xref: UnificationXref2255
cellular location: GO_0005759
comment: Reactome DB_ID: 5593465

alpha-keto acid dehydrogenase E3 holoenzyme (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry287
component stoichiometry: Stoichiometry288
component: Protein281
component: SmallMolecule206
xref: UnificationXref2254
cellular location: GO_0005759
comment: Reactome DB_ID: 5593464

pyruvate dehydrogenase E2 trimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry291
component: Protein282
xref: UnificationXref2258
cellular location: GO_0005759
comment: Reactome DB_ID: 5593542

UnificationXref2006
type: UnificationXref
id: CHEBI:17858
db: ChEBI

UnificationXref2007
type: UnificationXref
id: 111745
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=111745

lactate dehydrogenase AB3 complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry278
component stoichiometry: Stoichiometry279
component: Protein272
component: Protein96
xref: UnificationXref2223
cellular location: GO_0005829
comment: Reactome DB_ID: 5593390

UnificationXref2008
type: UnificationXref
id: REACT_3495
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3495.2

MPC1:MPC2 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry281
component stoichiometry: Stoichiometry280
component: Protein276
component: Protein277
xref: UnificationXref2235
cellular location: GO_0005743
comment: Reactome DB_ID: 5595024

http://identifiers.org/pubmed/21937421
type: PublicationXref
id: 21937421
author: Forties, Robert A
author: Punja, Nidhi
author: Cyr, Jennifer L
author: Fishel, Richard
author: Cook, Christopher
author: Sakato, Miho
author: Lopez, Juana Martin
author: Hingorani, Manju M
author: Heinen, Christopher D
db: Pubmed
title: Human MSH2 (hMSH2) protein controls ATP processing by hMSH2-hMSH6
source: J. Biol. Chem. 286:40287-95
year: 2011

UnificationXref2009
type: UnificationXref
id: CHEBI:28209
db: ChEBI

pyruvate dehydrogenase complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry286
component stoichiometry: Stoichiometry285
component stoichiometry: Stoichiometry290
component stoichiometry: Stoichiometry292
component: pyruvate dehydrogenase E1 complex (name copied from entity in Homo sapiens)
component: alpha-keto acid dehydrogenase E3 homodimer (name copied from entity in Homo sapiens)
component: pyruvate dehydrogenase E2 trimer (name copied from entity in Homo sapiens)
component: Protein280
xref: UnificationXref2259
cellular location: GO_0005759
comment: Reactome DB_ID: 5593544

Role of LAT2/NTAL/LAB on calcium mobilization
type: Pathway
data source: Provenance1
pathway component: REACT 237994.1
evidence: Evidence757
xref: UnificationXref4550
xref: UnificationXref4549
pathway order: PathwayStep77
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref2002
type: UnificationXref
id: REACT_235596
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_235596.1

http://identifiers.org/pubmed/11226282
type: PublicationXref
id: 11226282
author: Watanabe, D
author: Matsushita, M
author: Hashimoto, S
author: Baba, Y
author: Kurosaki, T
author: Kishimoto, T
author: Tsukada, S
db: Pubmed
title: BLNK mediates Syk-dependent Btk activation
source: Proc Natl Acad Sci U S A 98:2582-6
year: 2001

UnificationXref2003
type: UnificationXref
id: CHEBI:15632
db: ChEBI

http://identifiers.org/pubmed/19443651
type: PublicationXref
id: 19443651
author: Wang, Jianghai
author: Fukui, Lisa
author: Lee, Brian
author: Cai, Sheng
author: Chen, Yuan
author: Hu, Weidong
db: Pubmed
title: Conformational transition associated with E1-E2 interaction in small ubiquitin-like modifications
source: J. Biol. Chem. 284:20340-8
year: 2009

UnificationXref2004
type: UnificationXref
id: 266010
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=266010

UnificationXref2005
type: UnificationXref
id: REACT_15596
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15596.2

UnificationXref2000
type: UnificationXref
id: REACT_237680
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_237680.1

UnificationXref2001
type: UnificationXref
id: 5596949
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596949

lactate dehydrogenase A4 complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry277
component: Protein272
xref: UnificationXref2222
cellular location: GO_0005829
comment: Reactome DB_ID: 5593389

lactate dehydrogenase A3B complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry276
component stoichiometry: Stoichiometry275
component: Protein272
component: Protein96
xref: UnificationXref2221
cellular location: GO_0005829
comment: Reactome DB_ID: 5593388

lactate dehydrogenase A2B2 complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry273
component stoichiometry: Stoichiometry274
component: Protein272
component: Protein96
xref: UnificationXref2220
cellular location: GO_0005829
comment: Reactome DB_ID: 5593387

lactate dehydrogenase complex
type: Complex
data source: Provenance1
member physical entity: Complex29
member physical entity: lactate dehydrogenase AB3 complex (name copied from entity in Homo sapiens)
member physical entity: lactate dehydrogenase A4 complex (name copied from entity in Homo sapiens)
member physical entity: lactate dehydrogenase A3B complex (name copied from entity in Homo sapiens)
member physical entity: lactate dehydrogenase A2B2 complex (name copied from entity in Homo sapiens)
xref: UnificationXref2224
cellular location: GO_0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5593392

GCH1 decamer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry272
component: GCH1 dimer (name copied from entity in Homo sapiens)
xref: UnificationXref2197
cellular location: GO_0005829
comment: Reactome DB_ID: 5595930

http://identifiers.org/pubmed/6105839
type: PublicationXref
id: 6105839
author: Jones, ME
db: Pubmed
title: Pyrimidine nucleotide biosynthesis in animals: genes, enzymes, and regulation of UMP biosynthesis.
source: Annu Rev Biochem 49:253-79
year: 1980

GCH1 dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry271
component: Protein271
xref: UnificationXref2196
cellular location: GO_0005829
comment: Reactome DB_ID: 5595929

http://identifiers.org/pubmed/16738315
type: PublicationXref
id: 16738315
author: Lee, Hsiang-Ying
author: Gill, Grace
author: Catic, Andre
author: Di Bacco, A
author: Ouyang, Jian
author: Ploegh, Hidde
db: Pubmed
title: The SUMO-specific protease SENP5 is required for cell division
source: Mol. Cell. Biol. 26:4489-98
year: 2006

p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry259
component stoichiometry: Stoichiometry260
component stoichiometry: Stoichiometry263
component stoichiometry: Stoichiometry262
component stoichiometry: Stoichiometry261
component: p-S1177-eNOS dimer (name copied from entity in Homo sapiens)
component: Protein92
component: Protein95
component: Complex24
component: SmallMolecule319
xref: UnificationXref2158
cellular location: GO_0005886
comment: Reactome DB_ID: 5594846

p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry266
component stoichiometry: Stoichiometry267
component stoichiometry: Stoichiometry268
component stoichiometry: Stoichiometry269
component stoichiometry: Stoichiometry270
component: p-S1177-eNOS dimer (name copied from entity in Homo sapiens)
component: SmallMolecule325
component: Protein92
component: Protein95
component: Complex24
xref: UnificationXref2181
cellular location: GO_0005886
comment: Reactome DB_ID: 5596046

http://identifiers.org/pubmed/16169847
type: PublicationXref
id: 16169847
author: Treadwell, L
author: Warrington, JA
author: Wolfe, CL
author: Norcum, MT
db: Pubmed
title: A three-dimensional working model of the multienzyme complex of aminoacyl-tRNA synthetases based on electron microscopic placements of tRNA and proteins
source: J Biol Chem 280:38870-8
year: 2005

p-S1177-eNOS:CaM:HSP90:p-AKT1 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry258
component stoichiometry: Stoichiometry250
component stoichiometry: Stoichiometry251
component stoichiometry: Stoichiometry249
component: p-S1177-eNOS dimer (name copied from entity in Homo sapiens)
component: Protein92
component: Protein95
component: Complex24
xref: UnificationXref2155
cellular location: GO_0005886
comment: Reactome DB_ID: 5594844

p-S1177-eNOS dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry256
component stoichiometry: Stoichiometry257
component stoichiometry: Stoichiometry254
component stoichiometry: Stoichiometry255
component stoichiometry: Stoichiometry252
component stoichiometry: Stoichiometry253
component: PhysicalEntity7
component: SmallMolecule135
component: SmallMolecule134
component: SmallMolecule5
component: SmallMolecule24
component: SmallMolecule319
xref: UnificationXref2154
cellular location: GO_0005886
comment: Reactome DB_ID: 5594843

Oxaloacetate [ChEBI:30744]
type: SmallMoleculeReference
name: Oxalacetic acid
name: Oxosuccinic acid
name: 2-oxobutanedioic acid
name: Oxaloacetic acid
name: Oxaloacetate
xref: UnificationXref761

UnificationXref3591
type: UnificationXref
id: REACT_203689
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_203689.2

UnificationXref3592
type: UnificationXref
id: 68424
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=68424

UnificationXref3590
type: UnificationXref
id: 5596662
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596662

dihydroorotate dehydrogenase holoenzyme (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry325
component stoichiometry: Stoichiometry326
component: Protein302
component: SmallMolecule371
xref: UnificationXref2471
cellular location: GO_0005743
comment: Reactome DB_ID: 5593842

http://identifiers.org/pubmed/15153069
type: PublicationXref
id: 15153069
author: Lake, S
author: Climent, I
author: Swiezewska, E
author: Forsgren, M
author: Attersand, A
author: Dallner, G
author: Grünler, J
db: Pubmed
title: Isolation and functional expression of human COQ2, a gene encoding a polyprenyl transferase involved in the synthesis of CoQ
source: Biochem J 382:519-26
year: 2004

adenylosuccinate synthetase holoenzyme (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry312
component stoichiometry: Stoichiometry313
component: Protein294
component: SmallMolecule96
xref: UnificationXref2366
cellular location: GO_0005829
comment: Reactome DB_ID: 5594262

AMPD tetramers
type: Complex
data source: Provenance1
member physical entity: AMPD1 tetramer (name copied from entity in Homo sapiens)
member physical entity: AMPD2 tetramer (name copied from entity in Homo sapiens)
member physical entity: AMPD3 tetramer (name copied from entity in Homo sapiens)
xref: UnificationXref2410
cellular location: GO_0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5594129

AMPD1 tetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry315
component: Protein296
xref: UnificationXref2405
cellular location: GO_0005829
comment: Reactome DB_ID: 5594124

AMPD2 tetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry316
component: Protein297
xref: UnificationXref2407
cellular location: GO_0005829
comment: Reactome DB_ID: 5594126

AMPD3 tetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry317
component: Protein298
xref: UnificationXref2409
cellular location: GO_0005829
comment: Reactome DB_ID: 5594128

ADAL:Zn (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry319
component stoichiometry: Stoichiometry318
component: Protein299
component: SmallMolecule24
xref: UnificationXref2420
cellular location: GO_0005829
comment: Reactome DB_ID: 5596274

HGPRT homotetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry321
component stoichiometry: Stoichiometry320
component: Protein300
component: SmallMolecule96
xref: UnificationXref2433
cellular location: GO_0005829
comment: Reactome DB_ID: 5593921

CAD hexamer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry324
component: Protein301
xref: UnificationXref2445
cellular location: GO_0005829
comment: Reactome DB_ID: 5593847

UnificationXref3596
type: UnificationXref
id: 5593138
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593138

UnificationXref3595
type: UnificationXref
id: REACT_3288
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3288.1

UnificationXref3594
type: UnificationXref
id: 68422
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=68422

UnificationXref3593
type: UnificationXref
id: REACT_2531
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2531.1

UnificationXref3599
type: UnificationXref
id: REACT_3748
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3748.1

UnificationXref3598
type: UnificationXref
id: 113499
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113499

UniProt:PFI0960w
type: ProteinReference
xref: UnificationXref4457
organism: http://identifiers.org/taxonomy/5833

adenylosuccinate synthetase holoenzyme dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry314
component: adenylosuccinate synthetase holoenzyme (name copied from entity in Homo sapiens)
xref: UnificationXref2367
cellular location: GO_0005829
comment: Reactome DB_ID: 5594263

UnificationXref3597
type: UnificationXref
id: 5593254
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593254

Hydroxybenzenecarboxylic acid
type: SmallMoleculeReference
name: 4-Hydroxybenzoate
name: 4-Hydroxybenzoic acid [ChEBI:30763]
name: Hydroxybenzoic acid
name: 4-Hydroxybenzoic acid
xref: UnificationXref2071

UnificationXref3580
type: UnificationXref
id: 5593131
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593131

http://identifiers.org/pubmed/14514684
type: PublicationXref
id: 14514684
author: Rebholz, H
author: Foxon, R
author: Matsuka, G
author: Fenton, T
author: Valovka, T
author: Nemazanyy, I
author: Zhyvoloup, A
author: Filonenko, V
author: Wang, ML
author: Lyzogubov, V
author: Usenko, V
author: Gorbenko, O
author: Kyyamova, R
author: Gout, IT
author: Panasyuk, G
db: Pubmed
title: Subcellular localization and regulation of coenzyme A synthase
source: J Biol Chem 278:50316-21
year: 2003

UnificationXref3581
type: UnificationXref
id: PFL1655c
db: UniProt

adenylosuccinate synthetase like 1 holoenzyme (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry309
component stoichiometry: Stoichiometry310
component: Protein293
component: SmallMolecule96
xref: UnificationXref2363
cellular location: GO_0005829
comment: Reactome DB_ID: 5594259

http://identifiers.org/pubmed/17336609
type: PublicationXref
id: 17336609
author: Kambayashi, Taku
author: Koretzky, Gary A
db: Pubmed
title: Proximal signaling events in Fc epsilon RI-mediated mast cell activation
source: J. Allergy Clin. Immunol. 119:544-52; quiz 553-4
year: 2007

adenylosuccinate synthetase like 1 holoenzyme dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry311
component: adenylosuccinate synthetase like 1 holoenzyme (name copied from entity in Homo sapiens)
xref: UnificationXref2364
cellular location: GO_0005829
comment: Reactome DB_ID: 5594260

UniProt:PFF0895w
type: ProteinReference
xref: UnificationXref570
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/18555844
type: PublicationXref
id: 18555844
author: Buehrer, B
author: Madan, AK
author: Fain, JN
author: Bahouth, SW
author: Tichansky, DS
db: Pubmed
title: Comparison of messenger RNA distribution for 60 proteins in fat cells vs the nonfat cells of human omental adipose tissue
source: Metabolism 57:1005-15
year: 2008

http://identifiers.org/pubmed/17266529
type: PublicationXref
id: 17266529
author: Hyde, JE
db: Pubmed
title: Targeting purine and pyrimidine metabolism in human apicomplexan parasites
source: Curr Drug Targets 8:31-47
year: 2007

alpha-ketoglutarate dehydrogenase E1 holoenzyme (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry297
component stoichiometry: Stoichiometry298
component: SmallMolecule334
component: Protein286
xref: UnificationXref2295
cellular location: GO_0005759
comment: Reactome DB_ID: 5593498

alpha-ketoglutarate dehydrogenase E2 holoenzyme (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry303
component stoichiometry: Stoichiometry302
component: SmallMolecule341
component: Protein287
xref: UnificationXref2302
cellular location: GO_0005759
comment: Reactome DB_ID: 5593503

alpha-ketoglutarate dehydrogenase complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry304
component stoichiometry: Stoichiometry301
component stoichiometry: Stoichiometry300
component: alpha-ketoglutarate dehydrogenase E2 holoenzyme (name copied from entity in Homo sapiens)
component: alpha-keto acid dehydrogenase E3 homodimer (name copied from entity in Homo sapiens)
component: alpha-ketoglutarate dehydrogenase E1 homodimer (name copied from entity in Homo sapiens)
xref: UnificationXref2303
cellular location: GO_0005759
comment: Reactome DB_ID: 5593504

alpha-ketoglutarate dehydrogenase E1 homodimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry299
component: alpha-ketoglutarate dehydrogenase E1 holoenzyme (name copied from entity in Homo sapiens)
xref: UnificationXref2296
cellular location: GO_0005759
comment: Reactome DB_ID: 5593499

IMP (inosine monophosphate) dehydrogenase 1 tetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry308
component: Protein291
xref: UnificationXref2344
cellular location: GO_0005829
comment: Reactome DB_ID: 5593903

ADSS, ADSSL1 dimers
type: Complex
data source: Provenance1
member physical entity: adenylosuccinate synthetase like 1 holoenzyme dimer (name copied from entity in Homo sapiens)
member physical entity: adenylosuccinate synthetase holoenzyme dimer (name copied from entity in Homo sapiens)
xref: UnificationXref2368
cellular location: GO_0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5594264

Succinyl-CoA synthetase heterodimer (ADP-forming) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry306
component stoichiometry: Stoichiometry305
component: Protein289
component: Protein288
xref: UnificationXref2313
cellular location: GO_0005759
comment: Reactome DB_ID: 5593493

Hexose transport
type: Pathway
data source: Provenance1
pathway component: REACT 256642.1
evidence: Evidence12
xref: RelationshipXref12
xref: UnificationXref94
xref: UnificationXref95
pathway order: PathwayStep11
display name: Hexose uptake
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

adenylosuccinate lyase tetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry307
component: Protein290
xref: UnificationXref2333
cellular location: GO_0005829
comment: Reactome DB_ID: 5593909

UnificationXref3583
type: UnificationXref
id: 5593134
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593134

UnificationXref3582
type: UnificationXref
id: 5593133
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593133

UnificationXref3585
type: UnificationXref
id: 5593136
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593136

UnificationXref3584
type: UnificationXref
id: 5593135
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593135

UnificationXref3587
type: UnificationXref
id: REACT_206437
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_206437.2

2-Hydroxytricarballylic acid
type: SmallMoleculeReference
name: 2-Hydroxy-1,2,3-propanetricarboxylic acid
name: Citric acid [ChEBI:30769]
name: Citric acid
xref: UnificationXref1340

UnificationXref3586
type: UnificationXref
id: 5593141
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593141

UnificationXref3589
type: UnificationXref
id: REACT_217227
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_217227.2

UnificationXref3588
type: UnificationXref
id: 5593271
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593271

UniProt:MAL13P1.118
type: ProteinReference
xref: UnificationXref3244
organism: http://identifiers.org/taxonomy/5833

PCYT1 dimer
type: Complex
data source: Provenance1
member physical entity: PCYT1A dimer (name copied from entity in Homo sapiens)
member physical entity: PCYT1B dimer (name copied from entity in Homo sapiens)
xref: UnificationXref1707
cellular location: GO_0005789
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5596003

UniProt:MAL13P1.119
type: ProteinReference
xref: UnificationXref3240
organism: http://identifiers.org/taxonomy/5833

PCYT1A dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry197
component: Protein224
xref: UnificationXref1704
cellular location: GO_0005789
comment: Reactome DB_ID: 5596000

PCYT1B dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry198
component: Protein225
xref: UnificationXref1706
cellular location: GO_0005789
comment: Reactome DB_ID: 5596002

http://identifiers.org/pubmed/12700044
type: PublicationXref
id: 12700044
author: Maness, PF
author: Thelen, K
author: Panicker, AK
author: Buhusi, M
db: Pubmed
title: Cellular signalling mechanisms of neural cell adhesion molecules
source: Front Biosci 8:d900-11
year: 2003

LPIN3:Mg2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry190
component stoichiometry: Stoichiometry191
component: SmallMolecule227
component: Protein216
xref: UnificationXref1640
cellular location: GO_0005789
comment: Reactome DB_ID: 5596029

CEPT1:Mg2+/Mn2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry192
component stoichiometry: Stoichiometry193
component: SmallMolecule230
component: Protein217
xref: UnificationXref1657
cellular location: GO_0005789
comment: Reactome DB_ID: 5595972

PISD:Pyruvoyl (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry194
component stoichiometry: Stoichiometry195
component stoichiometry: Stoichiometry196
component: SmallMolecule235
component: Protein220
component: Protein221
xref: UnificationXref1672
cellular location: GO_0005743
comment: Reactome DB_ID: 5596036

CHK dimer
type: Complex
data source: Provenance1
member physical entity: Complex96
member physical entity: Complex97
member physical entity: Complex98
xref: UnificationXref1696
cellular location: GO_0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5595995

http://identifiers.org/pubmed/19228687
type: PublicationXref
id: 19228687
author: Tian, Lei
author: Gu, Liya
author: Li, Guo-Min
db: Pubmed
title: Distinct nucleotide binding/hydrolysis properties and molar ratio of MutSalpha and MutSbeta determine their differential mismatch binding activities
source: J. Biol. Chem. 284:11557-62
year: 2009

Formation of incision complex in GG-NER
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction366
evidence: Evidence690
xref: UnificationXref4225
xref: UnificationXref4224
pathway order: PathwayStep673
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

LPIN
type: Complex
data source: Provenance1
member physical entity: LPIN3:Mg2+ (name copied from entity in Homo sapiens)
member physical entity: LPIN2:Mg2+ (name copied from entity in Homo sapiens)
member physical entity: LPIN1:Mg2+ (name copied from entity in Homo sapiens)
xref: UnificationXref1641
cellular location: GO_0005789
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5596030

LPIN2:Mg2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry189
component stoichiometry: Stoichiometry188
component: SmallMolecule227
component: Protein198
xref: UnificationXref1638
cellular location: GO_0005789
comment: Reactome DB_ID: 5596027

LPIN1:Mg2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry186
component stoichiometry: Stoichiometry187
component: SmallMolecule227
component: Protein197
xref: UnificationXref1637
cellular location: GO_0005789
comment: Reactome DB_ID: 5596026

http://identifiers.org/pubmed/22112783
type: PublicationXref
id: 22112783
author: Amin, Kawa
db: Pubmed
title: The role of mast cells in allergic inflammation
source: Respir Med 106:9-14
year: 2012

UniProt:PFE0285c
type: ProteinReference
xref: UnificationXref5210
organism: http://identifiers.org/taxonomy/5833

ADP/ATP translocase 1 homodimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry236
component: Protein265
xref: UnificationXref2126
cellular location: GO_0005743
comment: Reactome DB_ID: 5594440

eNOS:CaM:HSP90:p-AKT1 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry248
component stoichiometry: Stoichiometry247
component: Protein270
component: eNOS:CaM:HSP90 (name copied from entity in Homo sapiens)
xref: UnificationXref2150
cellular location: GO_0005886
comment: Reactome DB_ID: 5594841

UniProt:MAL13P1.134
type: ProteinReference
xref: UnificationXref5291
organism: http://identifiers.org/taxonomy/5833

eNOS:CaM:HSP90 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry240
component stoichiometry: Stoichiometry246
component stoichiometry: Stoichiometry237
component: Active Calmodulin (name copied from entity in Homo sapiens)
component: palmitoylated, myristoylated eNOS dimer (name copied from entity in Homo sapiens)
component: Protein268
xref: UnificationXref2148
cellular location: GO_0005886
comment: Reactome DB_ID: 5594839

Active Calmodulin (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry239
component stoichiometry: Stoichiometry238
component: Protein269
component: SmallMolecule162
xref: UnificationXref2145
cellular location: GO_0005886
comment: Reactome DB_ID: 5594836

palmitoylated, myristoylated eNOS dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry241
component stoichiometry: Stoichiometry242
component stoichiometry: Stoichiometry245
component stoichiometry: Stoichiometry244
component stoichiometry: Stoichiometry243
component: PhysicalEntity7
component: SmallMolecule135
component: SmallMolecule134
component: SmallMolecule5
component: SmallMolecule24
xref: UnificationXref2147
cellular location: GO_0005886
comment: Reactome DB_ID: 5594834

Inositol phosphate metabolism
type: Pathway
data source: Provenance1
pathway component: REACT 192442.3
pathway component: REACT 192743.3
pathway component: Synthesis of pyrophosphates in the cytosol
pathway component: REACT 192443.3
evidence: Evidence226
xref: RelationshipXref170
xref: UnificationXref1306
xref: UnificationXref1305
pathway order: PathwayStep217
pathway order: PathwayStep212
pathway order: PathwayStep220
pathway order: PathwayStep223
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

HPGDS dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry226
component stoichiometry: Stoichiometry225
component: SmallMolecule294
component: Protein248
xref: UnificationXref1985
cellular location: GO_0005829
comment: Reactome DB_ID: 5596282

serine palymitoyltransferase
type: Complex
data source: Provenance1
member physical entity: SPTLC1:SPTLC3 (name copied from entity in Homo sapiens)
member physical entity: SPTLC1:SPTLC2 (name copied from entity in Homo sapiens)
xref: UnificationXref2048
cellular location: GO_0005789
display name: SPTLC 2 or 3 complexes
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5595332

triciribine
type: SmallMoleculeReference
name: triciribine [ChEBI:65310]
xref: UnificationXref651

LTA4H:Zn2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry228
component stoichiometry: Stoichiometry227
component: Protein249
component: SmallMolecule24
xref: UnificationXref1998
cellular location: GO_0005829
comment: Reactome DB_ID: 5594967

SPTLC1:SPTLC3 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry235
component stoichiometry: Stoichiometry234
component: Protein254
component: Protein253
xref: UnificationXref2047
cellular location: GO_0005789
comment: Reactome DB_ID: 5595331

SPTLC1:SPTLC2 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry233
component stoichiometry: Stoichiometry232
component: Protein253
component: Protein252
xref: UnificationXref2045
cellular location: GO_0005789
comment: Reactome DB_ID: 5595328

PIP4K2A:PIP4K2A (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry209
component: Protein243
xref: UnificationXref1852
cellular location: GO_0005829
comment: Reactome DB_ID: 5596052

UniProt:MAL13P1.146
type: ProteinReference
xref: UnificationXref2403
organism: http://identifiers.org/taxonomy/5833

PIP4K2A:PIP4K2B (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry211
component stoichiometry: Stoichiometry210
component: Protein244
component: Protein243
xref: UnificationXref1854
cellular location: GO_0005829
comment: Reactome DB_ID: 5596054

http://identifiers.org/pubmed/10448521
type: PublicationXref
id: 10448521
author: Seetharam, B
db: Pubmed
title: Receptor-mediated endocytosis of cobalamin (vitamin B12)
source: Annu. Rev. Nutr. 19:173-95
year: 1999

ARF1/3:GTP:PI4KB (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry207
component stoichiometry: Stoichiometry208
component: Protein239
component: ARF1:GTP (name copied from entity in Homo sapiens)
xref: UnificationXref1827
cellular location: GO_0000139
comment: Reactome DB_ID: 5596072

PIP4K2A/B
type: Complex
data source: Provenance1
member physical entity: PIP4K2A:PIP4K2A (name copied from entity in Homo sapiens)
member physical entity: PIP4K2A:PIP4K2B (name copied from entity in Homo sapiens)
member physical entity: PIP4K2B:PIP4K2B (name copied from entity in Homo sapiens)
xref: UnificationXref1856
cellular location: GO_0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5596056

Branched-chain amino acid catabolism
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction256
pathway component: BiochemicalReaction257
pathway component: BiochemicalReaction258
evidence: Evidence446
xref: UnificationXref2819
xref: UnificationXref2820
xref: RelationshipXref445
pathway order: PathwayStep442
pathway order: PathwayStep440
pathway order: PathwayStep441
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

PIP4K2B:PIP4K2B (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry212
component: Protein244
xref: UnificationXref1855
cellular location: GO_0005829
comment: Reactome DB_ID: 5596055

ACSL1 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry214
component stoichiometry: Stoichiometry213
component: Protein176
component: SmallMolecule227
xref: UnificationXref1898
cellular location: GO_0005789
comment: Reactome DB_ID: 5596256

http://identifiers.org/pubmed/2793178
type: PublicationXref
id: 2793178
author: Povey, S
author: Benham, FJ
db: Pubmed
title: Members of the human glyceraldehyde-3-phosphate dehydrogenase-related gene family map to dispersed chromosomal locations.
source: Genomics 5:209-14
year: 1989

http://identifiers.org/pubmed/9335335
type: PublicationXref
id: 9335335
author: Bell, SP
author: Aparicio, OM
author: Weinstein, DM
db: Pubmed
title: Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase.
source: Cell 91:59-69
year: 1997

UniProt:MAL13P1.144
type: ProteinReference
xref: UnificationXref4723
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/4340992
type: PublicationXref
id: 4340992
author: Fielding, PE
author: Shore, VG
author: Fielding, CJ
db: Pubmed
title: Lecithin: cholesterol acyltransferase: effects of substrate composition upon enzyme activity
source: Biochim Biophys Acta 270:513-8
year: 1972

http://identifiers.org/pubmed/16738331
type: PublicationXref
id: 16738331
author: Itahana, Yoko
author: Yeh, Edward T H
author: Zhang, Yanping
db: Pubmed
title: Nucleocytoplasmic shuttling modulates activity and ubiquitination-dependent turnover of SUMO-specific protease 2
source: Mol. Cell. Biol. 26:4675-89
year: 2006

alvespimycin [ChEBI:65324]
type: SmallMoleculeReference
name: alvespimycin
xref: UnificationXref521

ARF1:GTP (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry205
component stoichiometry: Stoichiometry206
component: SmallMolecule261
component: Protein238
xref: UnificationXref1825
cellular location: GO_0000139
comment: Reactome DB_ID: 5596071

CDIPT:Mg2+/Mn2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry203
component stoichiometry: Stoichiometry204
component: SmallMolecule230
component: Protein232
xref: UnificationXref1761
cellular location: GO_0005789
comment: Reactome DB_ID: 5595986

CDS1:Mg2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry201
component stoichiometry: Stoichiometry202
component: SmallMolecule227
component: Protein231
xref: UnificationXref1753
cellular location: GO_0005789
comment: Reactome DB_ID: 5596012

CHPT1:Mg2+/Mn2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry200
component stoichiometry: Stoichiometry199
component: SmallMolecule243
component: Protein226
xref: UnificationXref1724
cellular location: GO_0000139
comment: Reactome DB_ID: 5595981

Mitochondrial ABC transporters
type: Pathway
data source: Provenance1
pathway component: ABC7, mABC1 and mABC2 mediate heme transport
pathway component: MTABC3 transports porphyrin into mitochondria
evidence: Evidence3
xref: UnificationXref49
xref: UnificationXref50
pathway order: PathwayStep2
pathway order: PathwayStep1
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref5787
type: UnificationXref
id: REACT_248889
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_248889.1

UnificationXref5786
type: UnificationXref
id: 5596935
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596935

UnificationXref5789
type: UnificationXref
id: REACT_249423
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_249423.1

UnificationXref5788
type: UnificationXref
id: 5596709
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596709

UnificationXref5783
type: UnificationXref
id: REACT_256993
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_256993.1

http://identifiers.org/pubmed/17531985
type: PublicationXref
id: 17531985
author: Wittkopp, N
author: Rehwinkel, J
author: Kashima, I
author: Behm-Ansmant, I
author: Izaurralde, E
author: Saulière, J
db: Pubmed
title: mRNA quality control: an ancient machinery recognizes and degrades mRNAs with nonsense codons
source: FEBS Lett 581:2845-53
year: 2007

UnificationXref5782
type: UnificationXref
id: 5594862
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594862

UnificationXref5785
type: UnificationXref
id: REACT_246886
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_246886.1

http://identifiers.org/pubmed/15317809
type: PublicationXref
id: 15317809
author: Van Remmen, Holly
author: Muller, Florian L
author: Liu, Yuhong
db: Pubmed
title: Complex III releases superoxide to both sides of the inner mitochondrial membrane
source: J. Biol. Chem. 279:49064-73
year: 2004

UnificationXref5784
type: UnificationXref
id: 5596934
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596934

Nuclear Envelope Breakdown
type: Pathway
data source: Provenance1
pathway component: REACT 204630.2
evidence: Evidence592
xref: UnificationXref3845
xref: UnificationXref3846
xref: RelationshipXref541
pathway order: PathwayStep581
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref5780
type: UnificationXref
id: 203828
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=203828

UnificationXref5781
type: UnificationXref
id: REACT_12806
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_12806.1

http://identifiers.org/pubmed/15280035
type: PublicationXref
id: 15280035
author: Kissner, Reinhard
author: Nauser, Thomas
author: Koppenol, Willem H
author: Vander Stricht, Delphine
author: Clippe, André
author: Dubuisson, Marlène
author: Etienne, Florence
author: Rees, Jean-François
author: Knoops, Bernard
db: Pubmed
title: Human peroxiredoxin 5 is a peroxynitrite reductase
source: FEBS Lett. 571:161-5
year: 2004

http://identifiers.org/pubmed/10970868
type: PublicationXref
id: 10970868
author: Bell, SP
author: Klemm, RD
author: Lee, DG
author: Makhov, AM
db: Pubmed
title: Regulation of origin recognition complex conformation and ATPase activity: differential effects of single-stranded and double-stranded DNA binding.
source: EMBO J 19:4774-82
year: 2000

http://identifiers.org/pubmed/15519848
type: PublicationXref
id: 15519848
author: Reissmann, S
author: Meyer, AS
author: Frydman, J
author: Spiess, C
db: Pubmed
title: Mechanism of the eukaryotic chaperonin: protein folding in the chamber of secrets
source: Trends Cell Biol 14:598-604
year: 2004

UnificationXref5799
type: UnificationXref
id: 5596484
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596484

UnificationXref5798
type: UnificationXref
id: PFF1130c
db: UniProt

UnificationXref5797
type: UnificationXref
id: REACT_2551
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2551.2

UnificationXref5796
type: UnificationXref
id: 113533
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113533

UnificationXref5795
type: UnificationXref
id: REACT_116583
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_116583.1

UnificationXref5794
type: UnificationXref
id: 1614617
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1614617

http://identifiers.org/pubmed/12482854
type: PublicationXref
id: 12482854
author: Horton, JD
author: Moon, YA
db: Pubmed
title: Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade
source: J Biol Chem 278:7335-43
year: 2003

UnificationXref5793
type: UnificationXref
id: REACT_173459
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_173459.1

UnificationXref5791
type: UnificationXref
id: REACT_229745
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_229745.1

UnificationXref5792
type: UnificationXref
id: 3299683
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=3299683

UnificationXref5790
type: UnificationXref
id: 5596706
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596706

UniProt:MAL8P1.142
type: ProteinReference
xref: UnificationXref3694
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/9712840
type: PublicationXref
id: 9712840
author: Kikuchi, Y
author: Mizutani, M
author: Katada, T
author: Imai, M
author: Hoshino, S
author: Hanaoka, F
author: Ui, M
db: Pubmed
title: Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1.
source: J Biol Chem 273:22254-9
year: 1998

Stoichiometry698
type: Stoichiometry
physical entity: PhysicalEntity24
stoichiometric coefficient: 2.0

Stoichiometry699
type: Stoichiometry
physical entity: Protein590
stoichiometric coefficient: 1.0

Stoichiometry696
type: Stoichiometry
physical entity: Protein587
stoichiometric coefficient: 2.0

Stoichiometry697
type: Stoichiometry
physical entity: SPO11 Dimer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry694
type: Stoichiometry
physical entity: SmallMolecule521
stoichiometric coefficient: 1.0

Stoichiometry695
type: Stoichiometry
physical entity: PCNA homotrimer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

UnificationXref5769
type: UnificationXref
id: 5595505
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595505

UnificationXref5768
type: UnificationXref
id: 5595504
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595504

http://identifiers.org/pubmed/15534001
type: PublicationXref
id: 15534001
author: Allison, JG
author: Williams, CC
author: Beckman, BS
author: Jones, FE
author: Vidal, GA
author: Burow, ME
author: Marrero, L
db: Pubmed
title: The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone
source: J Cell Biol 167:469-78
year: 2004

http://identifiers.org/pubmed/11952783
type: PublicationXref
id: 11952783
author: Kurachi, Y
author: Kishida, K
author: Matsuzawa, Y
author: Makino, Y
author: Matsuda, M
author: Kondo, H
author: Nakamura, T
author: Kuriyama, H
author: Nagaretani, H
author: Maeda, N
author: Nishizawa, H
author: Funahashi, T
author: Shimomura, I
author: Kihara, S
db: Pubmed
title: Human aquaporin adipose (AQPap) gene. Genomic structure, promoter analysis and functional mutation
source: Eur J Biochem 269:1814-26
year: 2002

http://identifiers.org/pubmed/15944408
type: PublicationXref
id: 15944408
author: Waku, K
author: Suzuki, H
author: Kamata, R
author: Yamashita, A
author: Sugiura, T
author: Nakanishi, H
author: Kawagishi, N
db: Pubmed
title: Roles of C-terminal processing, and involvement in transacylation reaction of human group IVC phospholipase A2 (cPLA2gamma)
source: J Biochem 137:557-67
year: 2005

UnificationXref5761
type: UnificationXref
id: REACT_15875
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15875.1

UnificationXref5760
type: UnificationXref
id: 379735
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379735

UnificationXref5763
type: UnificationXref
id: REACT_15572
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15572.1

UnificationXref5762
type: UnificationXref
id: 379782
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379782

UnificationXref5765
type: UnificationXref
id: 5595144
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595144

UnificationXref5764
type: UnificationXref
id: 5595142
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595142

UnificationXref5767
type: UnificationXref
id: 5595503
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595503

UnificationXref5766
type: UnificationXref
id: REACT_174167
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_174167.3

http://identifiers.org/pubmed/16539657
type: PublicationXref
id: 16539657
author: Kakiuchi, C
author: Hayashi, A
author: Ishiwata, M
author: Kato, T
db: Pubmed
title: XBP1 induces WFS1 through an endoplasmic reticulum stress response element-like motif in SH-SY5Y cells
source: J Neurochem 97:545-55
year: 2006

herbimycin
type: SmallMoleculeReference
name: herbimycin [ChEBI:5674]
xref: UnificationXref527

UnificationXref5779
type: UnificationXref
id: REACT_243848
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_243848.1

http://identifiers.org/pubmed/10834843
type: PublicationXref
id: 10834843
author: Tercero, JA
author: Labib, K
author: Diffley, JF
db: Pubmed
title: Uninterrupted MCM2-7 function required for DNA replication fork progression.
source: Science 288:1643-7
year: 2000

UnificationXref5774
type: UnificationXref
id: 109496
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=109496

UnificationXref5773
type: UnificationXref
id: 5595509
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595509

UnificationXref5772
type: UnificationXref
id: REACT_256945
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_256945.1

UnificationXref5771
type: UnificationXref
id: 5595508
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595508

UnificationXref5778
type: UnificationXref
id: 5596708
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596708

UnificationXref5777
type: UnificationXref
id: REACT_254969
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_254969.1

UnificationXref5776
type: UnificationXref
id: 5596956
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596956

UnificationXref5775
type: UnificationXref
id: REACT_3508
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3508.3

http://identifiers.org/pubmed/21147620
type: PublicationXref
id: 21147620
author: Gorska, Elzbieta
author: Popko, K
author: Stelmaszczyk-Emmel, A
author: Wasik, M
author: Ciepiela, O
author: Kucharska, A
db: Pubmed
title: Leptin receptors
source: Eur. J. Med. Res. 15:50-4
year: 2010

UnificationXref5770
type: UnificationXref
id: 5595506
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595506

http://identifiers.org/pubmed/9587028
type: PublicationXref
id: 9587028
author: Fowler, B
db: Pubmed
title: Genetic defects of folate and cobalamin metabolism
source: Eur. J. Pediatr. 157:S60-6
year: 1998

http://identifiers.org/pubmed/11896061
type: PublicationXref
id: 11896061
author: Hang, Jun
author: Dasso, Mary
db: Pubmed
title: Association of the human SUMO-1 protease SENP2 with the nuclear pore
source: J. Biol. Chem. 277:19961-6
year: 2002

Stoichiometry670
type: Stoichiometry
physical entity: Protein583
stoichiometric coefficient: 1.0

Stoichiometry671
type: Stoichiometry
physical entity: RNA primer-DNA primer:origin duplex (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/15489917
type: PublicationXref
id: 15489917
author: Gauld, SB
author: Cambier, JC
db: Pubmed
title: Src-family kinases in B-cell development and signaling
source: Oncogene 23:8001-6
year: 2004

Stoichiometry666
type: Stoichiometry
physical entity: Protein579
stoichiometric coefficient: 1.0

Stoichiometry665
type: Stoichiometry
physical entity: Protein577
stoichiometric coefficient: 1.0

Stoichiometry668
type: Stoichiometry
physical entity: Protein581
stoichiometric coefficient: 1.0

Stoichiometry667
type: Stoichiometry
physical entity: Protein580
stoichiometric coefficient: 1.0

Stoichiometry662
type: Stoichiometry
physical entity: Protein577
stoichiometric coefficient: 1.0

Stoichiometry661
type: Stoichiometry
physical entity: Protein576
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/8257433
type: PublicationXref
id: 8257433
author: Hopkinson, DA
author: Edwards, YH
author: Whitehouse, DB
author: Ives, JH
author: Hollyoake, M
author: Putt, W
db: Pubmed
title: Phosphoglucomutase 1: a gene with two promoters and a duplicated first exon
source: Biochem J 296:417-22
year: 1993

Stoichiometry664
type: Stoichiometry
physical entity: Protein574
stoichiometric coefficient: 1.0

Stoichiometry663
type: Stoichiometry
physical entity: Protein572
stoichiometric coefficient: 1.0

Stoichiometry669
type: Stoichiometry
physical entity: Protein582
stoichiometric coefficient: 1.0

IGF1R signaling cascade
type: Pathway
data source: Provenance1
pathway component: REACT 192034.3
pathway component: REACT 240431.1
evidence: Evidence814
xref: UnificationXref4668
xref: UnificationXref4667
pathway order: PathwayStep793
pathway order: PathwayStep794
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

Stoichiometry660
type: Stoichiometry
physical entity: Protein575
stoichiometric coefficient: 1.0

UniProt:PFD0265w
type: ProteinReference
xref: UnificationXref5423
organism: http://identifiers.org/taxonomy/5833

Stoichiometry657
type: Stoichiometry
physical entity: Protein572
stoichiometric coefficient: 1.0

Stoichiometry656
type: Stoichiometry
physical entity: Protein518
stoichiometric coefficient: 1.0

Stoichiometry655
type: Stoichiometry
physical entity: Protein571
stoichiometric coefficient: 1.0

Stoichiometry654
type: Stoichiometry
physical entity: PhysicalEntity15
stoichiometric coefficient: 1.0

Stoichiometry653
type: Stoichiometry
physical entity: Protein569
stoichiometric coefficient: 1.0

Stoichiometry652
type: Stoichiometry
physical entity: Protein568
stoichiometric coefficient: 1.0

Stoichiometry651
type: Stoichiometry
physical entity: Protein567
stoichiometric coefficient: 1.0

Stoichiometry650
type: Stoichiometry
physical entity: Protein566
stoichiometric coefficient: 1.0

Stoichiometry659
type: Stoichiometry
physical entity: Protein574
stoichiometric coefficient: 1.0

Stoichiometry658
type: Stoichiometry
physical entity: Protein573
stoichiometric coefficient: 1.0

UniProt:PF13_0023
type: ProteinReference
xref: UnificationXref4246
organism: http://identifiers.org/taxonomy/5833

Stoichiometry690
type: Stoichiometry
physical entity: RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry691
type: Stoichiometry
physical entity: PCNA homotrimer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

UniProt:MAL8P1.128
type: ProteinReference
xref: UnificationXref3708
organism: http://identifiers.org/taxonomy/5833

Stoichiometry692
type: Stoichiometry
physical entity: PhysicalEntity18
stoichiometric coefficient: 1.0

Stoichiometry693
type: Stoichiometry
physical entity: PhysicalEntity17
stoichiometric coefficient: 1.0

Stoichiometry684
type: Stoichiometry
physical entity: RNA primer:G-strand extended telomere end:DNA polymerase alpha:primase complex (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry683
type: Stoichiometry
physical entity: SmallMolecule521
stoichiometric coefficient: 1.0

Stoichiometry686
type: Stoichiometry
physical entity: PhysicalEntity18
stoichiometric coefficient: 1.0

Stoichiometry685
type: Stoichiometry
physical entity: PhysicalEntity17
stoichiometric coefficient: 1.0

Stoichiometry688
type: Stoichiometry
physical entity: PhysicalEntity17
stoichiometric coefficient: 1.0

Stoichiometry687
type: Stoichiometry
physical entity: RFC Heteropentamer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry689
type: Stoichiometry
physical entity: SmallMolecule521
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/12474143
type: PublicationXref
id: 12474143
author: Carlson, Christopher G
author: Hoffbuhr, Kristen C
author: Kennaway, Nancy G
author: Glerum, D Moira
author: Antonicka, Hana
author: Leary, Scot C
author: Shoubridge, EA
author: Mattman, Andre
db: Pubmed
title: Mutations in COX15 produce a defect in the mitochondrial heme biosynthetic pathway, causing early-onset fatal hypertrophic cardiomyopathy
source: Am. J. Hum. Genet. 72:101-14
year: 2003

http://identifiers.org/pubmed/8619816
type: PublicationXref
id: 8619816
author: Kondo, M
author: Itakura, M
author: Takahashi, Y
author: Moritani, M
author: Yoshimoto, K
author: Yamaoka, T
author: Fujimura, H
author: Ii, S
author: Iwahana, H
db: Pubmed
title: Molecular cloning of a human cDNA encoding a trifunctional enzyme of carbamoyl-phosphate synthetase-aspartate transcarbamoylase-dihydroorotase in de Novo pyrimidine synthesis
source: Biochem Biophys Res Commun 219:249-255
year: 1996

UniProt:PF13_0019
type: ProteinReference
xref: UnificationXref410
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/7909354
type: PublicationXref
id: 7909354
author: Melki, R
author: Cowan, NJ
db: Pubmed
title: Facilitated folding of actins and tubulins occurs via a nucleotide-dependent interaction between cytoplasmic chaperonin and distinctive folding intermediates
source: Mol Cell Biol 14:2895-904
year: 1994

http://identifiers.org/pubmed/9697839
type: PublicationXref
id: 9697839
author: Turck, CW
author: Kurosaki, T
author: Chan, AC
author: Fu, C
db: Pubmed
title: BLNK: a central linker protein in B cell activation
source: Immunity 9:93-103
year: 1998

UniProt:PF13_0014
type: ProteinReference
xref: UnificationXref3478
organism: http://identifiers.org/taxonomy/5833

UniProt:PF13_0013
type: ProteinReference
xref: UnificationXref5001
organism: http://identifiers.org/taxonomy/5833

Stoichiometry681
type: Stoichiometry
physical entity: PhysicalEntity18
stoichiometric coefficient: 1.0

Stoichiometry682
type: Stoichiometry
physical entity: DNA polymerase alpha:primase (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry680
type: Stoichiometry
physical entity: DNA polymerase alpha:primase (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry675
type: Stoichiometry
physical entity: PCNA homotrimer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry674
type: Stoichiometry
physical entity: RFC Heteropentamer:RNA primer-DNA primer:origin duplex (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

UniProt:MAL8P1.125
type: ProteinReference
xref: UnificationXref5587
organism: http://identifiers.org/taxonomy/5833

Stoichiometry673
type: Stoichiometry
physical entity: Protein496
stoichiometric coefficient: 3.0

Stoichiometry672
type: Stoichiometry
physical entity: RFC Heteropentamer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry679
type: Stoichiometry
physical entity: DNA polymerase epsilon:G-strand extended telomere end (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry678
type: Stoichiometry
physical entity: DNA polymerase epsilon (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry677
type: Stoichiometry
physical entity: PCNA homotrimer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry676
type: Stoichiometry
physical entity: RNA primer-DNA primer:origin duplex (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

UnificationXref4250
type: UnificationXref
id: PFC0155c
db: UniProt

UnificationXref4252
type: UnificationXref
id: PFA0505c
db: UniProt

Stoichiometry629
type: Stoichiometry
physical entity: Protein545
stoichiometric coefficient: 1.0

UnificationXref4251
type: UnificationXref
id: 5594005
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594005

Stoichiometry627
type: Stoichiometry
physical entity: Protein543
stoichiometric coefficient: 1.0

Stoichiometry628
type: Stoichiometry
physical entity: Protein544
stoichiometric coefficient: 1.0

Stoichiometry625
type: Stoichiometry
physical entity: Protein542
stoichiometric coefficient: 1.0

Stoichiometry626
type: Stoichiometry
physical entity: PhysicalEntity2
stoichiometric coefficient: 5.0

http://identifiers.org/pubmed/18173545
type: PublicationXref
id: 18173545
author: Calamita, G
author: Svelto, M
author: Portincasa, P
author: Palasciano, G
db: Pubmed
title: Aquaporins in the hepatobiliary tract. Which, where and what they do in health and disease
source: Eur J Clin Invest 38:1-10
year: 2008

Stoichiometry623
type: Stoichiometry
physical entity: Protein540
stoichiometric coefficient: 1.0

Stoichiometry624
type: Stoichiometry
physical entity: Protein541
stoichiometric coefficient: 1.0

Expression of BIP (78 kDa Glucose-regulated protein, GRP78, HSPA5)
type: TemplateReaction
data source: Provenance1
evidence: Evidence916
product: Protein391
xref: UnificationXref5279
xref: UnificationXref5280
participant: Protein391
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

Stoichiometry621
type: Stoichiometry
physical entity: Protein538
stoichiometric coefficient: 1.0

Expression of HSP90B1 (Endoplasmin)
type: TemplateReaction
data source: Provenance1
evidence: Evidence917
product: Endoplasmin
xref: UnificationXref5283
xref: UnificationXref5284
participant: Endoplasmin
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

Stoichiometry622
type: Stoichiometry
physical entity: Protein539
stoichiometric coefficient: 1.0

Stoichiometry620
type: Stoichiometry
physical entity: Protein537
stoichiometric coefficient: 1.0

UnificationXref5709
type: UnificationXref
id: REACT_216312
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_216312.2

Expression of GFPT1
type: TemplateReaction
data source: Provenance1
evidence: Evidence925
product: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5308
xref: UnificationXref5307
participant: Note: the coordinates are copied over from Homo sapiens.
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

UnificationXref5708
type: UnificationXref
id: 5595155
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595155

Expression of ARFGAP1 (GAP)
type: TemplateReaction
data source: Provenance1
evidence: Evidence924
product: ARFGAP1
xref: UnificationXref5306
xref: UnificationXref5305
participant: ARFGAP1
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

UnificationXref5707
type: UnificationXref
id: 5595153
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595153

Expression of HYOU1
type: TemplateReaction
data source: Provenance1
evidence: Evidence927
product: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5313
xref: UnificationXref5314
participant: Note: the coordinates are copied over from Homo sapiens.
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

D-Glucose 6-phosphate
type: SmallMoleculeReference
name: D-Glucose 6-phosphate [ChEBI:4170]
name: Robison ester
name: Glucose 6-phosphate
xref: UnificationXref1292

UnificationXref5706
type: UnificationXref
id: PFF0180w
db: UniProt

Expression of GSK3A
type: TemplateReaction
data source: Provenance1
evidence: Evidence926
product: Protein86
xref: UnificationXref5309
xref: UnificationXref5310
participant: Protein86
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

UnificationXref5705
type: UnificationXref
id: REACT_16119
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_16119.1

Expression of DDX11
type: TemplateReaction
data source: Provenance1
evidence: Evidence921
product: MAL13P1.134
xref: UnificationXref5294
xref: UnificationXref5293
participant: MAL13P1.134
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

UnificationXref5704
type: UnificationXref
id: 379789
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379789

Expression of ATP6VOD1
type: TemplateReaction
data source: Provenance1
evidence: Evidence920
product: Protein33
xref: UnificationXref5290
xref: UnificationXref5289
participant: Protein33
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

UnificationXref5703
type: UnificationXref
id: REACT_17466
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17466.1

Expression of DNAJB9
type: TemplateReaction
data source: Provenance1
evidence: Evidence923
product: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5302
xref: UnificationXref5301
participant: Note: the coordinates are copied over from Homo sapiens.
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

UnificationXref5702
type: UnificationXref
id: 379760
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379760

Expression of DNAJB11
type: TemplateReaction
data source: Provenance1
evidence: Evidence922
product: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5297
xref: UnificationXref5298
participant: Note: the coordinates are copied over from Homo sapiens.
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

UnificationXref5701
type: UnificationXref
id: CHEBI:29184
db: ChEBI

UnificationXref4257
type: UnificationXref
id: 5593999
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593999

UnificationXref5700
type: UnificationXref
id: 379701
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379701

UnificationXref4258
type: UnificationXref
id: 5594184
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594184

UnificationXref4259
type: UnificationXref
id: 110291
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=110291

UnificationXref4253
type: UnificationXref
id: 5593993
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593993

UnificationXref4254
type: UnificationXref
id: PF07_0027
db: UniProt

Conversion of palmitic acid to very long chain fatty acyl-CoAs
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction119
pathway component: BiochemicalReaction118
pathway component: BiochemicalReaction117
pathway component: BiochemicalReaction113
pathway component: BiochemicalReaction122
pathway component: BiochemicalReaction114
pathway component: BiochemicalReaction123
pathway component: BiochemicalReaction115
pathway component: BiochemicalReaction120
pathway component: BiochemicalReaction116
pathway component: BiochemicalReaction121
pathway component: BiochemicalReaction124
pathway component: BiochemicalReaction125
pathway component: BiochemicalReaction112
evidence: Evidence246
xref: UnificationXref1435
xref: UnificationXref1434
xref: RelationshipXref209
pathway order: PathwayStep242
pathway order: PathwayStep243
pathway order: PathwayStep240
pathway order: PathwayStep241
pathway order: PathwayStep230
pathway order: PathwayStep231
pathway order: PathwayStep232
pathway order: PathwayStep233
pathway order: PathwayStep234
pathway order: PathwayStep235
pathway order: PathwayStep236
pathway order: PathwayStep237
pathway order: PathwayStep238
pathway order: PathwayStep239
display name: Synthesis of very long-chain fatty acyl-CoAs
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4255
type: UnificationXref
id: 5594007
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594007

UnificationXref4256
type: UnificationXref
id: PFI1130c
db: UniProt

UnificationXref4263
type: UnificationXref
id: REACT_247805
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_247805.1

Stoichiometry618
type: Stoichiometry
physical entity: Protein535
stoichiometric coefficient: 1.0

UnificationXref4262
type: UnificationXref
id: 5594246
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594246

Stoichiometry619
type: Stoichiometry
physical entity: Protein536
stoichiometric coefficient: 1.0

UnificationXref4261
type: UnificationXref
id: 5594185
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594185

UnificationXref4260
type: UnificationXref
id: REACT_3022
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3022.1

Stoichiometry614
type: Stoichiometry
physical entity: Protein531
stoichiometric coefficient: 1.0

Stoichiometry615
type: Stoichiometry
physical entity: Protein532
stoichiometric coefficient: 1.0

Stoichiometry616
type: Stoichiometry
physical entity: Protein533
stoichiometric coefficient: 1.0

Stoichiometry617
type: Stoichiometry
physical entity: Protein534
stoichiometric coefficient: 1.0

Expression of PDIA5
type: TemplateReaction
data source: Provenance1
evidence: Evidence929
product: Homologues of PDIA5
xref: UnificationXref5325
xref: UnificationXref5324
participant: Homologues of PDIA5
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

Stoichiometry610
type: Stoichiometry
physical entity: Protein507
stoichiometric coefficient: 1.0

Expression of SRPR (SRP Receptor subunit alpha)
type: TemplateReaction
data source: Provenance1
evidence: Evidence930
product: Protein670
xref: UnificationXref5327
xref: UnificationXref5326
participant: Protein670
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

Stoichiometry611
type: Stoichiometry
physical entity: Protein518
stoichiometric coefficient: 1.0

Stoichiometry612
type: Stoichiometry
physical entity: Protein529
stoichiometric coefficient: 1.0

Expression of KDELR3
type: TemplateReaction
data source: Provenance1
evidence: Evidence928
product: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5317
xref: UnificationXref5318
participant: Note: the coordinates are copied over from Homo sapiens.
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

Stoichiometry613
type: Stoichiometry
physical entity: Protein530
stoichiometric coefficient: 1.0

UnificationXref5718
type: UnificationXref
id: 379732
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379732

PublicationXref1113
type: PublicationXref
id: 978-953-307-395-8
author: Murcia, Hansen
author: Diaz, Gonzalo
db: ISBN
title: Biotransformation of Aflatoxin B1 and Its Relationship with the Differential Toxicological Response to Aflatoxin in Commercial Poultry Species,
source: Aflatoxins - Biochemistry and Molecular Biology (Book)
year: 2011

Pol II mediated transcription of microRNA genes
type: TemplateReaction
data source: Provenance1
evidence: Evidence992
product: PhysicalEntity84
xref: UnificationXref5783
xref: UnificationXref5782
participant: PhysicalEntity84
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

UnificationXref5717
type: UnificationXref
id: REACT_244016
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_244016.1

Expression of Asparagine Synthetase
type: TemplateReaction
data source: Provenance1
evidence: Evidence940
product: Protein326
xref: UnificationXref5357
xref: UnificationXref5356
participant: Protein326
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

UnificationXref5719
type: UnificationXref
id: REACT_15595
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15595.2

Expression of WIPI1
type: TemplateReaction
data source: Provenance1
evidence: Evidence935
product: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5343
xref: UnificationXref5342
participant: Note: the coordinates are copied over from Homo sapiens.
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

UnificationXref5714
type: UnificationXref
id: PFI1240c
db: UniProt

Expression of TSPYL2
type: TemplateReaction
data source: Provenance1
evidence: Evidence934
product: PFI0930c
xref: UnificationXref5338
xref: UnificationXref5339
participant: PFI0930c
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

UnificationXref5713
type: UnificationXref
id: REACT_23357
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_23357.1

Expression of Sec31A
type: TemplateReaction
data source: Provenance1
evidence: Evidence933
product: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5334
xref: UnificationXref5335
participant: Note: the coordinates are copied over from Homo sapiens.
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

UnificationXref5716
type: UnificationXref
id: 5595141
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595141

Expression of SYVN1 (HRD1)
type: TemplateReaction
data source: Provenance1
evidence: Evidence932
product: E3 ubiquitin-protein ligase synoviolin
xref: UnificationXref5332
xref: UnificationXref5333
participant: E3 ubiquitin-protein ligase synoviolin
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

UnificationXref5715
type: UnificationXref
id: 5595139
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595139

Expression of SRPRB (SRP Receptor subunit beta)
type: TemplateReaction
data source: Provenance1
evidence: Evidence931
product: Protein671
xref: UnificationXref5329
xref: UnificationXref5328
participant: Protein671
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

UnificationXref5710
type: UnificationXref
id: 379775
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379775

UnificationXref5712
type: UnificationXref
id: 379745
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379745

UnificationXref4268
type: UnificationXref
id: 110303
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=110303

UnificationXref5711
type: UnificationXref
id: REACT_22591
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_22591.1

UnificationXref4269
type: UnificationXref
id: REACT_5428
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5428.1

UnificationXref4266
type: UnificationXref
id: 5596827
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596827

http://identifiers.org/pubmed/16978839
type: PublicationXref
id: 16978839
author: Mei, Y
author: Zhou, M
author: Liu, X
author: Li, Z
db: Pubmed
title: Neuregulin-1 only induces trans-phosphorylation between ErbB receptor heterodimer partners
source: Cell Signal 19:466-71
year: 2007

UnificationXref4267
type: UnificationXref
id: REACT_229926
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_229926.1

UnificationXref4264
type: UnificationXref
id: 5594186
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594186

UnificationXref4265
type: UnificationXref
id: REACT_248133
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_248133.1

Stoichiometry649
type: Stoichiometry
physical entity: Protein565
stoichiometric coefficient: 1.0

Stoichiometry647
type: Stoichiometry
physical entity: Protein563
stoichiometric coefficient: 1.0

Stoichiometry648
type: Stoichiometry
physical entity: Protein564
stoichiometric coefficient: 1.0

UnificationXref4230
type: UnificationXref
id: 109966
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=109966

http://identifiers.org/pubmed/12369887
type: PublicationXref
id: 12369887
author: Danielson, PB
db: Pubmed
title: The cytochrome P450 superfamily: biochemistry, evolution and drug metabolism in humans
source: Curr Drug Metab 3:561-97
year: 2002

Stoichiometry641
type: Stoichiometry
physical entity: Protein557
stoichiometric coefficient: 1.0

Stoichiometry642
type: Stoichiometry
physical entity: Protein558
stoichiometric coefficient: 1.0

Stoichiometry640
type: Stoichiometry
physical entity: Protein556
stoichiometric coefficient: 1.0

Stoichiometry645
type: Stoichiometry
physical entity: Protein561
stoichiometric coefficient: 1.0

Stoichiometry646
type: Stoichiometry
physical entity: Protein562
stoichiometric coefficient: 1.0

Stoichiometry643
type: Stoichiometry
physical entity: Protein559
stoichiometric coefficient: 1.0

Stoichiometry644
type: Stoichiometry
physical entity: Protein560
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/10692433
type: PublicationXref
id: 10692433
author: Kijima, S
author: Fujita, M
author: Arata, Y
author: Ohtani, K
author: Kato, JY
db: Pubmed
title: Cdk2-dependent and -independent pathways in E2F-mediated S phase induction
source: J Biol Chem 275:6337-45
year: 2000

UnificationXref4239
type: UnificationXref
id: 5593995
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593995

http://identifiers.org/pubmed/8723348
type: PublicationXref
id: 8723348
author: Jefferson, AB
author: Pot, DA
author: Deuter-Reinhard, M
author: Masiarz, FR
author: Cousens, LS
author: Williams, LT
author: Chin, SM
author: Norris, FA
author: Kavanaugh, WM
author: Majerus, PW
db: Pubmed
title: Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2
source: Curr Biol 6:438-45
year: 1996

http://identifiers.org/pubmed/3932573
type: PublicationXref
id: 3932573
author: Kuhl, W
author: Beutler, E
db: Pubmed
title: Limiting role of 6-phosphogluconolactonase in erythrocyte hexose monophosphate pathway metabolism
source: J Lab Clin Med 106:573-7
year: 1985

UnificationXref4231
type: UnificationXref
id: REACT_4318
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4318.1

UnificationXref4232
type: UnificationXref
id: 5593984
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593984

UnificationXref4233
type: UnificationXref
id: REACT_253148
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253148.1

UnificationXref4234
type: UnificationXref
id: 5596769
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596769

UnificationXref4235
type: UnificationXref
id: REACT_232593
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_232593.1

UnificationXref4236
type: UnificationXref
id: 5596770
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596770

UnificationXref4237
type: UnificationXref
id: REACT_257532
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_257532.1

UnificationXref4238
type: UnificationXref
id: PFB0715w
db: UniProt

Stoichiometry636
type: Stoichiometry
physical entity: Protein552
stoichiometric coefficient: 1.0

Stoichiometry637
type: Stoichiometry
physical entity: Protein553
stoichiometric coefficient: 1.0

Stoichiometry638
type: Stoichiometry
physical entity: Protein554
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/1894595
type: PublicationXref
id: 1894595
author: Burbaum, JJ
author: Schimmel, P
db: Pubmed
title: Structural relationships and the classification of aminoacyl-tRNA synthetases
source: J Biol Chem 266:16965-8
year: 1991

Stoichiometry639
type: Stoichiometry
physical entity: Protein555
stoichiometric coefficient: 1.0

UnificationXref4241
type: UnificationXref
id: 5594001
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594001

UnificationXref4240
type: UnificationXref
id: PFL0665c
db: UniProt

Stoichiometry630
type: Stoichiometry
physical entity: Protein546
stoichiometric coefficient: 1.0

Stoichiometry631
type: Stoichiometry
physical entity: Protein547
stoichiometric coefficient: 1.0

Stoichiometry632
type: Stoichiometry
physical entity: Protein548
stoichiometric coefficient: 1.0

Stoichiometry633
type: Stoichiometry
physical entity: Protein549
stoichiometric coefficient: 1.0

Stoichiometry634
type: Stoichiometry
physical entity: Protein550
stoichiometric coefficient: 1.0

Stoichiometry635
type: Stoichiometry
physical entity: Protein551
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/11815463
type: PublicationXref
id: 11815463
author: Sharp, GW
author: Liu, YJ
author: Gunawardana, S
author: Straub, SG
author: Mulvaney-Musa, J
author: Cheng, H
author: Schermerhorn, T
author: Yajima, H
author: Daniel, S
author: Bratanova-Tochkova, TK
db: Pubmed
title: Triggering and augmentation mechanisms, granule pools, and biphasic insulin secretion
source: Diabetes 51:S83-90
year: 2002

UnificationXref4244
type: UnificationXref
id: PF13_0341
db: UniProt

UnificationXref4245
type: UnificationXref
id: 5594003
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594003

UnificationXref4242
type: UnificationXref
id: PF10_0269
db: UniProt

UnificationXref4243
type: UnificationXref
id: 5593997
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593997

UnificationXref4248
type: UnificationXref
id: PFC0805w
db: UniProt

UnificationXref4249
type: UnificationXref
id: 5594183
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594183

UnificationXref4246
type: UnificationXref
id: PF13_0023
db: UniProt

UnificationXref4247
type: UnificationXref
id: 5593991
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593991

http://identifiers.org/pubmed/21173190
type: PublicationXref
id: 21173190
author: Agarwal, AK
author: Prasad, SS
author: Garg, A
db: Pubmed
title: Enzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria
source: J Lipid Res 52:451-62
year: 2011

UnificationXref5744
type: UnificationXref
id: 5595161
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595161

UnificationXref4214
type: UnificationXref
id: REACT_230536
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_230536.1

UnificationXref5745
type: UnificationXref
id: 5595163
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595163

UnificationXref4213
type: UnificationXref
id: 5596779
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596779

UnificationXref5742
type: UnificationXref
id: REACT_15822
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15822.1

UnificationXref4216
type: UnificationXref
id: REACT_257434
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_257434.1

UnificationXref5743
type: UnificationXref
id: PFL2485c
db: UniProt

UnificationXref4215
type: UnificationXref
id: 5596780
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596780

UnificationXref5740
type: UnificationXref
id: 379709
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379709

UnificationXref4210
type: UnificationXref
id: REACT_236025
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_236025.1

UnificationXref5741
type: UnificationXref
id: 379759
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379759

UnificationXref4212
type: UnificationXref
id: REACT_247363
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_247363.1

UnificationXref4211
type: UnificationXref
id: 5596778
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596778

UnificationXref3600
type: UnificationXref
id: 5594333
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594333

UnificationXref3601
type: UnificationXref
id: 5594334
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594334

UnificationXref3602
type: UnificationXref
id: REACT_259519
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_259519.1

UnificationXref3603
type: UnificationXref
id: 5596844
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596844

UnificationXref3604
type: UnificationXref
id: REACT_261846
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_261846.1

UniProt:PFF0740c
type: ProteinReference
xref: UnificationXref5027
organism: http://identifiers.org/taxonomy/5833

UnificationXref5748
type: UnificationXref
id: REACT_18191
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_18191.1

UnificationXref4218
type: UnificationXref
id: 5594176
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594176

UnificationXref3605
type: UnificationXref
id: 5596845
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596845

UnificationXref5749
type: UnificationXref
id: 379710
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379710

UnificationXref4217
type: UnificationXref
id: PFB0160w
db: UniProt

UnificationXref3606
type: UnificationXref
id: REACT_258875
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_258875.1

UnificationXref5746
type: UnificationXref
id: REACT_250951
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_250951.1

UnificationXref3607
type: UnificationXref
id: 5596663
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596663

UnificationXref5747
type: UnificationXref
id: 379756
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379756

UnificationXref4219
type: UnificationXref
id: MAL13P1.346
db: UniProt

UnificationXref3608
type: UnificationXref
id: REACT_220090
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_220090.2

UnificationXref3609
type: UnificationXref
id: 5596664
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596664

http://identifiers.org/pubmed/3143362
type: PublicationXref
id: 3143362
author: Sakuraba, H
author: Nagao, Y
author: Suzuki, Y
author: Tsuji, A
author: Oshima, A
db: Pubmed
title: Cloning, sequencing, and expression of cDNA for human beta-galactosidase
source: Biochem. Biophys. Res. Commun. 157:238-44
year: 1988

UnificationXref5753
type: UnificationXref
id: PF11_0181
db: UniProt

UnificationXref4227
type: UnificationXref
id: REACT_3448
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3448.1

UnificationXref5754
type: UnificationXref
id: 5595131
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595131

UnificationXref4226
type: UnificationXref
id: 109964
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=109964

UnificationXref5755
type: UnificationXref
id: 5595132
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595132

UnificationXref4225
type: UnificationXref
id: REACT_239755
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_239755.1

UnificationXref5756
type: UnificationXref
id: 5595134
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595134

UnificationXref4224
type: UnificationXref
id: 5596826
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596826

UnificationXref4223
type: UnificationXref
id: REACT_241398
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_241398.1

UnificationXref3610
type: UnificationXref
id: REACT_225646
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_225646.2

(S)-3-Hydroxyisobutyryl-CoA
type: SmallMoleculeReference
name: (S)-3-Hydroxyisobutyryl-CoA [ChEBI:28259]
xref: UnificationXref2809

UnificationXref5750
type: UnificationXref
id: REACT_15744
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15744.2

UnificationXref4222
type: UnificationXref
id: 5594180
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594180

UnificationXref3611
type: UnificationXref
id: 29470
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29470

UnificationXref5751
type: UnificationXref
id: 379755
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379755

UnificationXref4221
type: UnificationXref
id: 5594179
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594179

UnificationXref5752
type: UnificationXref
id: REACT_15651
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15651.1

UnificationXref4220
type: UnificationXref
id: 5594178
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594178

Glycerophospholipid biosynthesis
type: Pathway
data source: Provenance1
pathway component: REACT 192727.3
pathway component: REACT 217128.2
pathway component: REACT 192709.3
pathway component: REACT 192726.3
pathway component: Synthesis of PG
pathway component: REACT 192729.3
pathway component: REACT 192733.3
pathway component: Synthesis of PC
pathway component: Acyl chain remodelling of PC
pathway component: REACT 255397.1
evidence: Evidence308
xref: UnificationXref1801
xref: UnificationXref1802
xref: RelationshipXref286
pathway order: PathwayStep277
pathway order: PathwayStep294
pathway order: PathwayStep283
pathway order: PathwayStep291
pathway order: PathwayStep300
pathway order: PathwayStep305
pathway order: PathwayStep271
pathway order: PathwayStep297
pathway order: PathwayStep303
pathway order: PathwayStep286
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref3614
type: UnificationXref
id: REACT_5587
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5587.1

UnificationXref3615
type: UnificationXref
id: 113562
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113562

UnificationXref3612
type: UnificationXref
id: REACT_2826
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2826.1

UnificationXref3613
type: UnificationXref
id: 113571
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113571

UnificationXref5757
type: UnificationXref
id: REACT_255742
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_255742.1

UnificationXref3618
type: UnificationXref
id: 5593140
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593140

UnificationXref5758
type: UnificationXref
id: 113540
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113540

UnificationXref3619
type: UnificationXref
id: REACT_211264
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_211264.2

http://identifiers.org/pubmed/9110970
type: PublicationXref
id: 9110970
author: Lingner, J
author: Shevchenko, A
author: Hughes, TR
author: Lundblad, V
author: Mann, M
author: Cech, TR
db: Pubmed
title: Reverse transcriptase motifs in the catalytic subunit of telomerase
source: Science 276:561-7
year: 1997

UnificationXref5759
type: UnificationXref
id: REACT_2426
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2426.2

UnificationXref4229
type: UnificationXref
id: REACT_3852
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3852.2

UnificationXref3616
type: UnificationXref
id: REACT_3782
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3782.1

UnificationXref4228
type: UnificationXref
id: 109961
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=109961

UnificationXref3617
type: UnificationXref
id: 5593137
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593137

http://identifiers.org/pubmed/3049610
type: PublicationXref
id: 3049610
author: Smith, BL
author: Agre, P
author: Denker, BM
author: Kuhajda, FP
db: Pubmed
title: Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules
source: J Biol Chem 263:15634-42
year: 1988

Stoichiometry602
type: Stoichiometry
physical entity: PhysicalEntity17
stoichiometric coefficient: 1.0

Stoichiometry601
type: Stoichiometry
physical entity: DNA polymerase epsilon:origin complex (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry600
type: Stoichiometry
physical entity: DNA polymerase alpha:primase (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

UnificationXref2095
type: UnificationXref
id: CHEBI:16680
db: ChEBI

Stoichiometry606
type: Stoichiometry
physical entity: RNA primer:origin duplex:DNA polymerase alpha:primase complex (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

UnificationXref2096
type: UnificationXref
id: 2162252
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2162252

Stoichiometry605
type: Stoichiometry
physical entity: PhysicalEntity16
stoichiometric coefficient: 1.0

UnificationXref2093
type: UnificationXref
id: 113529
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113529

Stoichiometry604
type: Stoichiometry
physical entity: DNA polymerase alpha:primase (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

UnificationXref2094
type: UnificationXref
id: REACT_5847
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5847.1

Stoichiometry603
type: Stoichiometry
physical entity: PhysicalEntity18
stoichiometric coefficient: 1.0

UnificationXref2091
type: UnificationXref
id: 2162215
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2162215

UnificationXref2092
type: UnificationXref
id: REACT_160433
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_160433.1

Stoichiometry609
type: Stoichiometry
physical entity: Protein495
stoichiometric coefficient: 1.0

Stoichiometry608
type: Stoichiometry
physical entity: PhysicalEntity19
stoichiometric coefficient: 1.0

UnificationXref2090
type: UnificationXref
id: CHEBI:50776
db: ChEBI

Stoichiometry607
type: Stoichiometry
physical entity: PhysicalEntity17
stoichiometric coefficient: 1.0

UnificationXref5722
type: UnificationXref
id: 379777
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379777

UnificationXref5723
type: UnificationXref
id: REACT_15932
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15932.1

UnificationXref2099
type: UnificationXref
id: 5596300
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596300

UnificationXref5720
type: UnificationXref
id: 379761
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379761

UnificationXref2098
type: UnificationXref
id: MAL7P1.130
db: UniProt

UnificationXref5721
type: UnificationXref
id: REACT_15998
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15998.1

UnificationXref2097
type: UnificationXref
id: REACT_161327
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_161327.1

http://identifiers.org/pubmed/9630604
type: PublicationXref
id: 9630604
author: Li, X
author: Hiratsuka, M
author: Suzuki, Y
author: Sakamoto, O
author: Narisawa, K
author: Aoki, Y
db: Pubmed
title: Identification of holocarboxylase synthetase (HCS) proteins in human placenta
source: Biochim. Biophys. Acta 1385:165-71
year: 1998

UnificationXref5726
type: UnificationXref
id: 5595182
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595182

UnificationXref5727
type: UnificationXref
id: 5595184
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595184

UnificationXref5724
type: UnificationXref
id: PFL0770w
db: UniProt

UnificationXref5725
type: UnificationXref
id: 5595181
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595181

UnificationXref5728
type: UnificationXref
id: REACT_250452
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_250452.1

UnificationXref5729
type: UnificationXref
id: 379706
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379706

http://identifiers.org/pubmed/17008356
type: PublicationXref
id: 17008356
author: Monroy, N
author: Kretz, C
author: Mandel, JL
author: Payrastre, B
author: Dondaine, N
author: Tronchère, H
author: Zanoteli, E
author: Rohde, HM
author: Tosch, V
author: Laporte, J
db: Pubmed
title: A novel PtdIns3P and PtdIns(3,5)P2 phosphatase with an inactivating variant in centronuclear myopathy
source: Hum Mol Genet 15:3098-106
year: 2006

http://identifiers.org/pubmed/8325892
type: PublicationXref
id: 8325892
author: Froguel, P
author: Velho, G
author: Stoffel, M
author: Vionnet, N
author: Cohen, D
author: Takeda, J
author: St. Charles, R
author: Bell, GI
author: Vaxillaire, M
author: Pilkis, SJ
author: Weber, IT
author: Gidh-Jain, M
author: Shimada, F
author: Nishi, S
author: Harrison, RW
author: Makino, H
author: Xu, LZ
db: Pubmed
title: Structure/function studies of human beta-cell glucokinase. Enzymatic properties of a sequence polymorphism, mutations associated with diabetes, and other site-directed mutants.
source: J Biol Chem 268:15200-4
year: 1993

UniProt:PFD1070w
type: ProteinReference
xref: UnificationXref4021
organism: http://identifiers.org/taxonomy/5833

UnificationXref4201
type: UnificationXref
id: 83898
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=83898

UnificationXref4200
type: UnificationXref
id: REACT_244874
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_244874.1

http://identifiers.org/pubmed/19855401
type: PublicationXref
id: 19855401
author: Wilkinson, RJ
author: Boshoff, HI
author: Young, D
author: Dartois, V
author: Ehrt, S
author: Flynn, J
author: Barry CE, 3rd
author: Schnappinger, D
author: Dick, T
db: Pubmed
title: The spectrum of latent tuberculosis: rethinking the biology and intervention strategies
source: Nat Rev Microbiol 7:845-55
year: 2009

UnificationXref5730
type: UnificationXref
id: REACT_15829
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15829.2

UnificationXref5731
type: UnificationXref
id: 379791
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379791

UnificationXref4205
type: UnificationXref
id: 5594085
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594085

UnificationXref5732
type: UnificationXref
id: REACT_15748
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15748.1

UnificationXref4204
type: UnificationXref
id: REACT_5857
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5857.1

UnificationXref5733
type: UnificationXref
id: 379779
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379779

UnificationXref4203
type: UnificationXref
id: 75220
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=75220

http://identifiers.org/pubmed/22649417
type: PublicationXref
id: 22649417
author: Siddle, Kenneth
db: Pubmed
title: Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances
source: Front Endocrinol (Lausanne) 3:34
year: 2012

UnificationXref5734
type: UnificationXref
id: REACT_17148
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17148.1

UnificationXref4202
type: UnificationXref
id: REACT_2357
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2357.1

UnificationXref5735
type: UnificationXref
id: 5595149
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595149

UnificationXref4209
type: UnificationXref
id: 5596777
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596777

UnificationXref5736
type: UnificationXref
id: 5595151
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595151

UnificationXref4208
type: UnificationXref
id: REACT_246414
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_246414.1

UnificationXref5737
type: UnificationXref
id: REACT_174284
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_174284.3

UnificationXref4207
type: UnificationXref
id: 5596776
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596776

http://identifiers.org/pubmed/17984070
type: PublicationXref
id: 17984070
author: Masih, Prerna Jasmine
author: Kunnev, Dimiter
author: Melendy, Thomas
db: Pubmed
title: Mismatch Repair proteins are recruited to replicating DNA through interaction with Proliferating Cell Nuclear Antigen (PCNA)
source: Nucleic Acids Res. 36:67-75
year: 2008

UnificationXref5738
type: UnificationXref
id: 379774
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379774

UnificationXref4206
type: UnificationXref
id: REACT_233603
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_233603.1

http://identifiers.org/pubmed/15632136
type: PublicationXref
id: 15632136
author: Kinoshita, T
author: Ashida, H
author: Shishioh, N
author: Hong, Y
author: Maeda, Y
author: Ohishi, K
db: Pubmed
title: GPI7 is the second partner of PIG-F and involved in modification of glycosylphosphatidylinositol
source: J Biol Chem 280:9728-34
year: 2005

UnificationXref5739
type: UnificationXref
id: REACT_15653
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15653.1

UnificationXref2187
type: UnificationXref
id: REACT_2875
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2875.1

UnificationXref2188
type: UnificationXref
id: CHEBI:30751
db: ChEBI

http://identifiers.org/pubmed/9405935
type: PublicationXref
id: 9405935
author: Fujiwara, T
author: Suzuki, K
author: Okutomi, K
author: Suzuki, M
author: Kanemoto, N
author: Hirano, H
author: Kuga, Y
author: Horie, M
author: Isono, K
db: Pubmed
title: Identification and characterization of a novel human phosphatidylinositol 4-kinase
source: DNA Res 4:273-80
year: 1997

UnificationXref2185
type: UnificationXref
id: REACT_261883
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_261883.1

UnificationXref2186
type: UnificationXref
id: 29438
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29438

UnificationXref3631
type: UnificationXref
id: REACT_203174
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_203174.2

UnificationXref3630
type: UnificationXref
id: 5596659
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596659

UnificationXref2189
type: UnificationXref
id: 29460
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29460

UnificationXref3633
type: UnificationXref
id: 5593149
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593149

UnificationXref3632
type: UnificationXref
id: 5593147
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593147

UnificationXref3635
type: UnificationXref
id: 5593151
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593151

UnificationXref3634
type: UnificationXref
id: PFL0585w
db: UniProt

UnificationXref3637
type: UnificationXref
id: 5593153
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593153

UnificationXref3636
type: UnificationXref
id: 5593152
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593152

ALAS1,2
type: Complex
data source: Provenance1
member physical entity: ALAS2 homodimer (pyridoxal phosphate cofactor) (name copied from entity in Homo sapiens)
member physical entity: ALAS1 homodimer (pyridoxal phosphate cofactor) (name copied from entity in Homo sapiens)
xref: UnificationXref2950
cellular location: GO_0005759
comment: Reactome DB_ID: 5594613
comment: Converted from EntitySet in Reactome

UnificationXref3639
type: UnificationXref
id: 5593155
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593155

ALAS1 homodimer (pyridoxal phosphate cofactor) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry377
component: Protein341
xref: UnificationXref2947
cellular location: GO_0005759
comment: Reactome DB_ID: 5594610

UnificationXref3638
type: UnificationXref
id: 5593154
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593154

http://identifiers.org/pubmed/7306699
type: PublicationXref
id: 7306699
author: Plow, EF
db: Pubmed
title: The presence and release of alpha 2-antiplasmin from human platelets
source: Blood 58:1069-74
year: 1981

HMBS:DIPY (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry391
component stoichiometry: Stoichiometry390
component: SmallMolecule475
component: Protein344
xref: UnificationXref2978
cellular location: GO_0005829
comment: Reactome DB_ID: 5594589

8xALAD:Pb2+:Zn2+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry382
component stoichiometry: Stoichiometry383
component stoichiometry: Stoichiometry384
component: SmallMolecule471
component: Protein343
component: SmallMolecule24
xref: UnificationXref2960
cellular location: GO_0005829
comment: Reactome DB_ID: 5594623

8x(ALAD:Zn2+) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry380
component stoichiometry: Stoichiometry381
component: Protein343
component: SmallMolecule24
xref: UnificationXref2959
cellular location: GO_0005829
comment: Reactome DB_ID: 5594604

ALAS2 homodimer (pyridoxal phosphate cofactor) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry378
component: Protein342
xref: UnificationXref2949
cellular location: GO_0005759
comment: Reactome DB_ID: 5594612

GSS (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry403
component stoichiometry: Stoichiometry402
component: Protein351
component: SmallMolecule96
xref: UnificationXref3074
cellular location: GO_0005829
comment: Reactome DB_ID: 5594522

2x(FECH:2Fe-2S cluster) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry400
component stoichiometry: Stoichiometry401
component: PhysicalEntity10
component: Protein347
xref: UnificationXref3026
cellular location: GO_0005759
comment: Reactome DB_ID: 5594619

2xCPO (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry398
component: Protein346
xref: UnificationXref3014
cellular location: GO_0005758
comment: Reactome DB_ID: 5594594

2xUROD (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry393
component: Protein345
xref: UnificationXref2989
cellular location: GO_0005829
comment: Reactome DB_ID: 5594599

UnificationXref2180
type: UnificationXref
id: REACT_111511
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_111511.1

http://identifiers.org/pubmed/21356517
type: PublicationXref
id: 21356517
author: Roach, PJ
author: Glushka, John
author: Contreras, Christopher J
author: Ishihara, Mayumi
author: Heiss, Christian
author: Tagliabracci, Vincent S
author: Hurley, TD
author: Karthik, Chandra
author: Azadi, Parastoo
author: DePaoli-Roach, Anna A
db: Pubmed
title: Phosphate incorporation during glycogen synthesis and Lafora disease
source: Cell Metab. 13:274-82
year: 2011

UnificationXref2184
type: UnificationXref
id: 5596928
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596928

UnificationXref2183
type: UnificationXref
id: REACT_231808
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_231808.1

UnificationXref2182
type: UnificationXref
id: 5596049
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596049

UnificationXref2181
type: UnificationXref
id: 5596046
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596046

UnificationXref2174
type: UnificationXref
id: REACT_239441
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_239441.1

UnificationXref2175
type: UnificationXref
id: CHEBI:18421
db: ChEBI

UnificationXref2176
type: UnificationXref
id: 1222424
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1222424

UnificationXref2177
type: UnificationXref
id: REACT_111446
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_111446.2

UnificationXref2178
type: UnificationXref
id: CHEBI:15375
db: ChEBI

UnificationXref3622
type: UnificationXref
id: 29892
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29892

UnificationXref2179
type: UnificationXref
id: 1497857
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1497857

UnificationXref3621
type: UnificationXref
id: REACT_2773
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2773.1

UnificationXref3620
type: UnificationXref
id: 30187
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=30187

UnificationXref3626
type: UnificationXref
id: 30185
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=30185

http://identifiers.org/pubmed/1939222
type: PublicationXref
id: 1939222
author: Cox, TM
author: Gardner, LC
author: Smith, SJ
db: Pubmed
title: Biosynthesis of delta-aminolevulinic acid and the regulation of heme formation by immature erythroid cells in man
source: J Biol Chem 266:22010-8
year: 1991

UnificationXref3625
type: UnificationXref
id: REACT_5621
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5621.1

http://identifiers.org/pubmed/12655297
type: PublicationXref
id: 12655297
author: Janicke, RU
author: Schulze-Osthoff, K
author: Fischer, U
db: Pubmed
title: Many cuts to ruin: a comprehensive update of caspase substrates
source: Cell Death Differ 10:76-100
year: 2003

UnificationXref3624
type: UnificationXref
id: 29604
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29604

UnificationXref3623
type: UnificationXref
id: REACT_4670
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4670.1

UnificationXref3629
type: UnificationXref
id: REACT_208781
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_208781.2

UnificationXref3628
type: UnificationXref
id: 5593256
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593256

UnificationXref3627
type: UnificationXref
id: REACT_5885
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5885.1

UnificationXref2171
type: UnificationXref
id: 202124
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=202124

UnificationXref2170
type: UnificationXref
id: CHEBI:16480
db: ChEBI

UnificationXref2173
type: UnificationXref
id: 5594848
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594848

UnificationXref2172
type: UnificationXref
id: REACT_13183
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_13183.2

UnificationXref3653
type: UnificationXref
id: 5593169
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593169

http://identifiers.org/pubmed/16311595
type: PublicationXref
id: 16311595
author: Forgetta, Vince
author: Tirone, Jamie C
author: Rosenblatt, DS
author: Watkins, D
author: Fujiwara, T Mary
author: Morel, Chantal F
author: Dunbar, Gail V
author: Dobson, C Melissa
author: Atkinson, Janet L
author: Shoubridge, EA
author: Pawelek, Peter D
author: Gravel, RA
author: Lerner-Ellis, Jordan P
author: Moras, Emily
author: Coulton, James W
author: Leclerc, Daniel
author: Doré, Carole
author: Morgan, Kenneth
author: Antonicka, Hana
author: Lepage, Pierre
author: Hosack, Angela R
author: Rommens, JM
db: Pubmed
title: Identification of the gene responsible for methylmalonic aciduria and homocystinuria, cblC type
source: Nat. Genet. 38:93-100
year: 2006

UnificationXref3652
type: UnificationXref
id: 5593168
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593168

UniProt:MAL8P1.22
type: ProteinReference
xref: UnificationXref5056
organism: http://identifiers.org/taxonomy/5833

UnificationXref3655
type: UnificationXref
id: 5593171
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593171

UnificationXref3654
type: UnificationXref
id: 5593170
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593170

UnificationXref3651
type: UnificationXref
id: 5593167
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593167

UnificationXref3650
type: UnificationXref
id: 5593166
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593166

http://identifiers.org/pubmed/10753735
type: PublicationXref
id: 10753735
author: Leroux, MR
author: Hartl, FU
db: Pubmed
title: Protein folding: versatility of the cytosolic chaperonin TRiC/CCT
source: Curr Biol 10:R260-4
year: 2000

http://identifiers.org/pubmed/18240029
type: PublicationXref
id: 18240029
author: Luttrell, LM
db: Pubmed
title: Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors
source: Mol Biotechnol 39:239-64
year: 2008

RNA Polymerase II Transcription
type: Pathway
data source: Provenance1
pathway component: REACT 252156.1
evidence: Evidence513
xref: UnificationXref3219
xref: UnificationXref3218
xref: RelationshipXref511
pathway order: PathwayStep506
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

Response to elevated platelet cytosolic Ca2+
type: Pathway
data source: Provenance1
pathway component: REACT 243308.1
evidence: Evidence534
xref: UnificationXref3306
xref: UnificationXref3307
pathway order: PathwayStep525
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref3657
type: UnificationXref
id: 5593173
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593173

UnificationXref3656
type: UnificationXref
id: 5593172
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593172

UnificationXref3659
type: UnificationXref
id: 5593175
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593175

UnificationXref3658
type: UnificationXref
id: 5593174
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593174

http://identifiers.org/pubmed/16321791
type: PublicationXref
id: 16321791
author: Joseph, JW
author: MacDonald, PE
author: Rorsman, P
db: Pubmed
title: Glucose-sensing mechanisms in pancreatic beta-cells
source: Philos Trans R Soc Lond B Biol Sci 360:2211-25
year: 2005

UnificationXref3644
type: UnificationXref
id: 5593160
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593160

UnificationXref3643
type: UnificationXref
id: 5593159
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593159

UnificationXref3642
type: UnificationXref
id: 5593158
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593158

UnificationXref3641
type: UnificationXref
id: 5593157
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593157

UnificationXref2196
type: UnificationXref
id: 5595929
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595929

UnificationXref3640
type: UnificationXref
id: 5593156
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593156

2,4-Dinitro-1-chlorobenzene
type: SmallMoleculeReference
name: 1-chloro-2,4-dinitrobenzene [ChEBI:34718]
name: DNCB
name: 1-Chloro-2,4-dinitrobenzol
name: 1-chloro-2,4-dinitrobenzene
name: Dncb
name: 6-Chloro-1,3-dinitrobenzene
name: Dinitrochlorobenzene
name: 1,3-Dinitro-4-chlorobenzene
name: Chlorodinitrobenzene
name: 2,4-Dinitrophenyl chloride
name: Cdnb
name: 4-Chloro-1,3-dinitrobenzene
name: 2,4-Dinitrochlorobenzene
xref: UnificationXref3086

5-HETE
type: SmallMoleculeReference
name: 5-Hydroxyeicosatetraenoate
name: 5-Hydroxyeicosatetraenoate [ChEBI:2068]
xref: UnificationXref2009

UnificationXref2197
type: UnificationXref
id: 5595930
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595930

UnificationXref2198
type: UnificationXref
id: 5595932
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595932

UnificationXref2199
type: UnificationXref
id: REACT_225837
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_225837.2

UnificationXref3649
type: UnificationXref
id: 5593165
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593165

UnificationXref3648
type: UnificationXref
id: 5593164
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593164

UnificationXref3647
type: UnificationXref
id: REACT_215438
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_215438.2

UnificationXref3646
type: UnificationXref
id: 5593163
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593163

UnificationXref3645
type: UnificationXref
id: 5593162
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593162

UnificationXref2193
type: UnificationXref
id: REACT_111890
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_111890.1

UnificationXref2192
type: UnificationXref
id: 1474124
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1474124

UnificationXref2195
type: UnificationXref
id: 5595928
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595928

UnificationXref2194
type: UnificationXref
id: PFL1155w
db: UniProt

http://identifiers.org/pubmed/6300847
type: PublicationXref
id: 6300847
author: Filpula, D
author: Johnson, GG
author: Esty, AC
author: Jolly, DJ
author: Okayama, H
author: Bohlen, P
author: Berg, P
author: Hunkapillar, T
author: Friedmann, T
author: Shively, JE
db: Pubmed
title: Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase
source: Proc Natl Acad Sci U S A 80:477-81
year: 1983

UnificationXref2191
type: UnificationXref
id: CHEBI:18372
db: ChEBI

UnificationXref2190
type: UnificationXref
id: REACT_4966
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4966.2

UnificationXref3678
type: UnificationXref
id: 5593247
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593247

UnificationXref3679
type: UnificationXref
id: PF10_0174
db: UniProt

UnificationXref2149
type: UnificationXref
id: 5594840
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594840

UnificationXref2144
type: UnificationXref
id: 5594835
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594835

UnificationXref3670
type: UnificationXref
id: 5593185
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593185

UnificationXref2143
type: UnificationXref
id: 5594838
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594838

UnificationXref3671
type: UnificationXref
id: PFI0370c
db: UniProt

UnificationXref2142
type: UnificationXref
id: REACT_229764
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_229764.1

UnificationXref3672
type: UnificationXref
id: 5593248
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593248

UnificationXref2141
type: UnificationXref
id: 5596862
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596862

UnificationXref3673
type: UnificationXref
id: MAL13P1.270
db: UniProt

UnificationXref2148
type: UnificationXref
id: 5594839
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594839

UnificationXref3674
type: UnificationXref
id: 5593249
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593249

UnificationXref2147
type: UnificationXref
id: 5594834
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594834

UnificationXref3675
type: UnificationXref
id: PF13_0282
db: UniProt

UnificationXref2146
type: UnificationXref
id: 5594833
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594833

UnificationXref3676
type: UnificationXref
id: 5593187
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593187

http://identifiers.org/pubmed/12573255
type: PublicationXref
id: 12573255
author: Hegele, RA
author: Cao, H
author: Mok, A
db: Pubmed
title: Genomic basis of mucopolysaccharidosis type IIID (MIM 252940) revealed by sequencing of GNS encoding N-acetylglucosamine-6-sulfatase
source: Genomics 81:1-5
year: 2003

UnificationXref2145
type: UnificationXref
id: 5594836
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594836

UnificationXref3677
type: UnificationXref
id: 5593246
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593246

http://identifiers.org/pubmed/15476407
type: PublicationXref
id: 15476407
author: Tsai, AL
author: Gao, D
author: Yeh, HC
author: Kiran, F
author: Berka, V
db: Pubmed
title: Redox function of tetrahydrobiopterin and effect of L-arginine on oxygen binding in endothelial nitric oxide synthase
source: Biochemistry 43:13137-48
year: 2004

UnificationXref2140
type: UnificationXref
id: REACT_255456
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_255456.1

http://identifiers.org/pubmed/15215243
type: PublicationXref
id: 15215243
author: Graf, SA
author: Shirihai, OS
author: Corson, ED
author: Haigh, SE
db: Pubmed
title: Targeting, import, and dimerization of a mammalian mitochondrial ATP binding cassette (ABC) transporter, ABCB10 (ABC-me)
source: J Biol Chem 279:42954-63
year: 2004

UnificationXref2139
type: UnificationXref
id: 5596863
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596863

UnificationXref3669
type: UnificationXref
id: PFC0745c
db: UniProt

UnificationXref2138
type: UnificationXref
id: REACT_99442
db: Reactome
id version: 4
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_99442.4

UnificationXref3667
type: UnificationXref
id: PFF0420c
db: UniProt

UnificationXref3668
type: UnificationXref
id: 5593183
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593183

UnificationXref2131
type: UnificationXref
id: 5596864
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596864

UnificationXref3661
type: UnificationXref
id: 5593177
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593177

UnificationXref2130
type: UnificationXref
id: REACT_79002
db: Reactome
id version: 4
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_79002.4

UnificationXref3662
type: UnificationXref
id: REACT_202704
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_202704.2

UnificationXref2133
type: UnificationXref
id: 5594443
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594443

UnificationXref2132
type: UnificationXref
id: REACT_260505
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_260505.1

UnificationXref3660
type: UnificationXref
id: 5593176
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593176

UnificationXref4399
type: UnificationXref
id: CHEBI:17895
db: ChEBI

UnificationXref2135
type: UnificationXref
id: 5594445
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594445

UnificationXref3665
type: UnificationXref
id: PF14_0716
db: UniProt

http://identifiers.org/pubmed/8428933
type: PublicationXref
id: 8428933
author: Doroshow, JH
author: Esworthy, RS
author: Chu, FF
db: Pubmed
title: Expression, characterization, and tissue distribution of a new cellular selenium-dependent glutathione peroxidase, GSHPx-GI
source: J Biol Chem 268:2571-6
year: 1993

http://identifiers.org/pubmed/12558974
type: PublicationXref
id: 12558974
author: Kolkova, K
author: Kohler, LB
author: Meyer, M
author: Pedersen, MV
author: Risell, M
author: Ditlevsen, DK
author: Berezin, V
author: Bock, E
db: Pubmed
title: The role of phosphatidylinositol 3-kinase in neural cell adhesion molecule-mediated neuronal differentiation and survival
source: J Neurochem 84:546-56
year: 2003

UnificationXref4398
type: UnificationXref
id: REACT_3188
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3188.2

UnificationXref2134
type: UnificationXref
id: REACT_243082
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_243082.1

UnificationXref3666
type: UnificationXref
id: 5593181
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593181

UnificationXref4397
type: UnificationXref
id: 29500
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29500

UnificationXref2137
type: UnificationXref
id: 5594447
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594447

UnificationXref3663
type: UnificationXref
id: PFI0630w
db: UniProt

UnificationXref4396
type: UnificationXref
id: CHEBI:16828
db: ChEBI

UnificationXref2136
type: UnificationXref
id: 5594446
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594446

UnificationXref3664
type: UnificationXref
id: 5593240
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593240

UnificationXref4394
type: UnificationXref
id: 351990
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=351990

UnificationXref4395
type: UnificationXref
id: REACT_14295
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_14295.2

UnificationXref4392
type: UnificationXref
id: REACT_2613
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2613.2

UnificationXref4393
type: UnificationXref
id: CHEBI:16857
db: ChEBI

UnificationXref4390
type: UnificationXref
id: REACT_14674
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_14674.2

UnificationXref4391
type: UnificationXref
id: 113538
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113538

UniProt:PFF1190c
type: ProteinReference
xref: UnificationXref5018
organism: http://identifiers.org/taxonomy/5833

ChEBI:60125 N-epsilon-(1-(1-carboxy)ethyl)lysine
type: SmallMoleculeReference
name: N-epsilon-(1-(1-carboxy)ethyl)lysine
xref: UnificationXref4465

UniProt:PFF1375c.2
type: ProteinReference
xref: UnificationXref1652
organism: http://identifiers.org/taxonomy/5833

UnificationXref3696
type: UnificationXref
id: PFL2345c
db: UniProt

UnificationXref2169
type: UnificationXref
id: REACT_3861
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3861.3

UnificationXref3697
type: UnificationXref
id: 5593220
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593220

UnificationXref2168
type: UnificationXref
id: 29968
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29968

UnificationXref3698
type: UnificationXref
id: PFA0400c
db: UniProt

UniProt:PFF1375c.1
type: ProteinReference
xref: UnificationXref1654
organism: http://identifiers.org/taxonomy/5833

UnificationXref2167
type: UnificationXref
id: CHEBI:16349
db: ChEBI

UnificationXref3699
type: UnificationXref
id: 5593201
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593201

UnificationXref2166
type: UnificationXref
id: REACT_2911
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2911.2

UnificationXref3692
type: UnificationXref
id: PF13_0033
db: UniProt

UnificationXref2165
type: UnificationXref
id: 29468
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29468

UnificationXref3693
type: UnificationXref
id: 5593222
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593222

UnificationXref2164
type: UnificationXref
id: CHEBI:16467
db: ChEBI

UnificationXref3694
type: UnificationXref
id: MAL8P1.142
db: UniProt

UnificationXref2163
type: UnificationXref
id: REACT_5251
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5251.2

UnificationXref3695
type: UnificationXref
id: 5593203
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593203

UnificationXref2161
type: UnificationXref
id: CHEBI:15379
db: ChEBI

UniProt:PFE0185c
type: ProteinReference
xref: UnificationXref3418
organism: http://identifiers.org/taxonomy/5833

UnificationXref2162
type: UnificationXref
id: 29368
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29368

UnificationXref3691
type: UnificationXref
id: 5593205
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593205

UnificationXref2160
type: UnificationXref
id: REACT_253197
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253197.1

UnificationXref3690
type: UnificationXref
id: 5593207
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593207

UnificationXref5900
type: UnificationXref
id: REACT_236678
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_236678.1

UnificationXref3689
type: UnificationXref
id: PFI1545c
db: UniProt

UnificationXref2157
type: UnificationXref
id: REACT_245575
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_245575.1

UnificationXref3687
type: UnificationXref
id: PFC0520w
db: UniProt

UnificationXref2156
type: UnificationXref
id: 5594845
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594845

UnificationXref3688
type: UnificationXref
id: 5593242
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593242

UnificationXref2159
type: UnificationXref
id: 5596045
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596045

UnificationXref3685
type: UnificationXref
id: PF10_0111
db: UniProt

UnificationXref2158
type: UnificationXref
id: 5594846
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594846

UnificationXref3686
type: UnificationXref
id: 5593209
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593209

UnificationXref2153
type: UnificationXref
id: REACT_2495
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2495.2

UnificationXref3683
type: UnificationXref
id: PFC0785c
db: UniProt

UnificationXref2152
type: UnificationXref
id: 29870
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29870

UnificationXref3684
type: UnificationXref
id: 5593244
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593244

http://identifiers.org/pubmed/14514735
type: PublicationXref
id: 14514735
author: Walker, RJ
author: Bedford, JJ
author: Leader, JP
db: Pubmed
title: Aquaporin expression in normal human kidney and in renal disease
source: J Am Soc Nephrol 14:2581-7
year: 2003

UnificationXref2155
type: UnificationXref
id: 5594844
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594844

UnificationXref3681
type: UnificationXref
id: PF07_0112
db: UniProt

UnificationXref2154
type: UnificationXref
id: 5594843
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594843

UnificationXref3682
type: UnificationXref
id: 5593189
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593189

UnificationXref3680
type: UnificationXref
id: 5593228
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593228

UnificationXref2150
type: UnificationXref
id: 5594841
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594841

UnificationXref2151
type: UnificationXref
id: CHEBI:15372
db: ChEBI

http://identifiers.org/pubmed/17560368
type: PublicationXref
id: 17560368
author: Peters, L
author: Meister, G
db: Pubmed
title: Argonaute proteins: mediators of RNA silencing
source: Mol Cell 26:611-23
year: 2007

http://identifiers.org/pubmed/1944596
type: PublicationXref
id: 1944596
author: Russell, DW
author: Andersson, S
author: Berman, DM
author: Jenkins, EP
db: Pubmed
title: Deletion of steroid 5 alpha-reductase 2 gene in male pseudohermaphroditism
source: Nature 354:159-61
year: 1991

UnificationXref2100
type: UnificationXref
id: 5596312
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596312

UnificationXref2101
type: UnificationXref
id: REACT_226019
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_226019.2

UnificationXref2102
type: UnificationXref
id: CHEBI:64180
db: ChEBI

SMG1:SMG8:SMG9 Complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry720
component: PhysicalEntity2
xref: UnificationXref4010
cellular location: GO_0005829
comment: Reactome DB_ID: 5595778

UnificationXref2103
type: UnificationXref
id: 2162205
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2162205

Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry744
component stoichiometry: Stoichiometry731
component stoichiometry: Stoichiometry734
component stoichiometry: Stoichiometry741
component stoichiometry: Stoichiometry722
component stoichiometry: Stoichiometry723
component: Protein611
component: Exon Junction:UPF2:UPF3 Complex (name copied from entity in Homo sapiens)
component: GDP bound eRF3 (name copied from entity in Homo sapiens)
component: mRNA Complex with a Premature Termination Codon Preceding an Exon Junction (name copied from entity in Homo sapiens)
component: 80S ribosome (name copied from entity in Homo sapiens)
component: SmallMolecule522
xref: UnificationXref4035
cellular location: GO_0005829
comment: Reactome DB_ID: 5595766

UnificationXref2104
type: UnificationXref
id: REACT_161345
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_161345.1

UniProt:PFD0590c
type: ProteinReference
xref: UnificationXref3562
organism: http://identifiers.org/taxonomy/5833

Exon Junction:UPF2:UPF3 Complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry730
component stoichiometry: Stoichiometry729
component: Core Exon Junction Complex (Core EJC) (name copied from entity in Homo sapiens)
component: PhysicalEntity2
xref: UnificationXref4024
cellular location: GO_0005829
comment: Reactome DB_ID: 5595765

UnificationXref2105
type: UnificationXref
id: CHEBI:64181
db: ChEBI

Core Exon Junction Complex (Core EJC) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry726
component stoichiometry: Stoichiometry727
component stoichiometry: Stoichiometry728
component: Protein614
component: Magoh-Y14 complex (name copied from entity in Homo sapiens)
component: PhysicalEntity2
xref: UnificationXref4023
cellular location: GO_0005829
comment: Reactome DB_ID: 5595764

UnificationXref2106
type: UnificationXref
id: 2162204
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2162204

Magoh-Y14 complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry724
component stoichiometry: Stoichiometry725
component: Protein612
component: Protein613
xref: UnificationXref4020
cellular location: GO_0005829
comment: Reactome DB_ID: 5595763

UnificationXref2107
type: UnificationXref
id: REACT_161541
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_161541.1

GDP bound eRF3 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry732
component stoichiometry: Stoichiometry733
component: SmallMolecule350
component: Protein615
xref: UnificationXref4027
cellular location: GO_0005829
comment: Reactome DB_ID: 5594350

UnificationXref2108
type: UnificationXref
id: PFB0220w
db: UniProt

mRNA Complex with a Premature Termination Codon Preceding an Exon Junction (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry740
component stoichiometry: Stoichiometry739
component stoichiometry: Stoichiometry736
component stoichiometry: Stoichiometry735
component: PhysicalEntity30
component: Cap Binding Complex (CBC) (name copied from entity in Homo sapiens)
component: Protein448
component: Protein447
xref: UnificationXref4033
cellular location: GO_0005829
comment: Reactome DB_ID: 5595758

UnificationXref2109
type: UnificationXref
id: 5596304
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596304

Cap Binding Complex (CBC) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry738
component stoichiometry: Stoichiometry737
component: Protein616
component: PhysicalEntity2
xref: UnificationXref4032
cellular location: GO_0005829
comment: Reactome DB_ID: 5595753

80S ribosome (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry743
component stoichiometry: Stoichiometry742
component: 60S ribosomal complex (name copied from entity in Homo sapiens)
component: 40S ribosomal complex (name copied from entity in Homo sapiens)
xref: UnificationXref4034
cellular location: GO_0005829
comment: Reactome DB_ID: 5593818

SMG1:Phosphorylated UPF1:EJC:Translated mRNP (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry748
component stoichiometry: Stoichiometry747
component stoichiometry: Stoichiometry746
component: SMG1:SMG8:SMG9 Complex (name copied from entity in Homo sapiens)
component: Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction (name copied from entity in Homo sapiens)
component: Protein617
xref: UnificationXref4038
cellular location: GO_0005829
comment: Reactome DB_ID: 5595780

http://identifiers.org/pubmed/6311078
type: PublicationXref
id: 6311078
author: Hammarström, Sven
db: Pubmed
title: Leukotrienes
source: Annu Rev Biochem 52:355-77
year: 1983

SMG1:UPF1:EJC:Translated mRNP (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry745
component stoichiometry: Stoichiometry719
component stoichiometry: Stoichiometry721
component: Protein610
component: SMG1:SMG8:SMG9 Complex (name copied from entity in Homo sapiens)
component: Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction (name copied from entity in Homo sapiens)
xref: UnificationXref4036
cellular location: GO_0005829
comment: Reactome DB_ID: 5595779

http://identifiers.org/pubmed/8892014
type: PublicationXref
id: 8892014
author: Treacy, E
author: Thompson, GN
author: Pitt, JJ
author: Cotton, RG
author: Seller, K
author: Ramus, S
db: Pubmed
title: In vivo disposal of phenylalanine in phenylketonuria: a study of two siblings
source: J Inherit Metab Dis 19:595-602
year: 1996

http://identifiers.org/pubmed/22527994
type: PublicationXref
id: 22527994
author: Monaga, Madelyn
author: Campos, Derbis
db: Pubmed
title: Mucopolysaccharidosis type I: current knowledge on its pathophysiological mechanisms
source: Metab Brain Dis 27:121-9
year: 2012

http://identifiers.org/pubmed/12126930
type: PublicationXref
id: 12126930
author: Jakobs, C
author: Patel, A
author: Geraghty, MT
author: Thomas, GH
author: Schor, DS
author: Salomons, GS
author: Goh, DL
db: Pubmed
title: Characterization of the human gene encoding alpha-aminoadipate aminotransferase (AADAT).
source: Mol Genet Metab 76:172-80
year: 2002

SPO11 Dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry696
component: Protein587
xref: UnificationXref3898
cellular location: GO_0005654
comment: Reactome DB_ID: 5595743

http://identifiers.org/pubmed/21245903
type: PublicationXref
id: 21245903
author: Kufer, TA
author: Sansonetti, PJ
db: Pubmed
title: NLR functions beyond pathogen recognition
source: Nat Immunol 12:121-8
year: 2011

Lsm1-7 Complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry706
component stoichiometry: Stoichiometry707
component stoichiometry: Stoichiometry704
component stoichiometry: Stoichiometry705
component stoichiometry: Stoichiometry702
component stoichiometry: Stoichiometry703
component stoichiometry: Stoichiometry701
component: Protein597
component: Protein598
component: Protein599
component: Protein594
component: Protein595
component: Protein596
component: PhysicalEntity2
xref: UnificationXref3961
cellular location: GO_0005829
comment: Reactome DB_ID: 5595397

Deadenylated mRNA:Lsm1-7 Complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry708
component stoichiometry: Stoichiometry709
component: Lsm1-7 Complex (name copied from entity in Homo sapiens)
component: PhysicalEntity25
xref: UnificationXref3964
cellular location: GO_0005829
comment: Reactome DB_ID: 5595403

SPO11:double stand break (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry698
component stoichiometry: Stoichiometry697
component: SPO11 Dimer (name copied from entity in Homo sapiens)
component: PhysicalEntity24
xref: UnificationXref3901
cellular location: GO_0005654
comment: Reactome DB_ID: 5595744

pPLCgamma:PIP2 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry700
component stoichiometry: Stoichiometry699
component: SmallMolecule69
component: Protein590
xref: UnificationXref3917
cellular location: GO_0005886
comment: Reactome DB_ID: 5595678

HuR with phosphoserine221 and phosphoserine318:mRNA Complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry714
component stoichiometry: Stoichiometry715
component: Protein604
component: PhysicalEntity28
xref: UnificationXref3993
cellular location: GO_0005654
comment: Reactome DB_ID: 5595605

HuR with Unknown Phosphorylation: mRNA Complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry716
component stoichiometry: Stoichiometry717
component: PhysicalEntity29
component: Protein607
xref: UnificationXref4001
cellular location: GO_0005654
comment: Reactome DB_ID: 5595517

Decapped mRNA:LSM1-7 Complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry710
component stoichiometry: Stoichiometry711
component: Lsm1-7 Complex (name copied from entity in Homo sapiens)
component: PhysicalEntity26
xref: UnificationXref3969
cellular location: GO_0005829
comment: Reactome DB_ID: 5595398

HuR with phosphoserine221 and phosphoserine158:mRNA Complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry713
component stoichiometry: Stoichiometry712
component: Protein601
component: PhysicalEntity27
xref: UnificationXref3985
cellular location: GO_0005654
comment: Reactome DB_ID: 5595603

RNA primer-DNA primer:G-strand extended telomere:PCNA (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry694
component stoichiometry: Stoichiometry692
component stoichiometry: Stoichiometry695
component stoichiometry: Stoichiometry693
component: SmallMolecule521
component: PCNA homotrimer (name copied from entity in Homo sapiens)
component: PhysicalEntity17
component: PhysicalEntity18
xref: UnificationXref3880
cellular location: GO_0005654
comment: Reactome DB_ID: 5594541

RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry690
component stoichiometry: Stoichiometry691
component: RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end (name copied from entity in Homo sapiens)
component: PCNA homotrimer (name copied from entity in Homo sapiens)
xref: UnificationXref3877
cellular location: GO_0005654
comment: Reactome DB_ID: 5594539

UnificationXref2123
type: UnificationXref
id: REACT_245466
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_245466.1

UnificationXref2124
type: UnificationXref
id: PF10_0366
db: UniProt

UnificationXref2125
type: UnificationXref
id: 5594439
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594439

UnificationXref2126
type: UnificationXref
id: 5594440
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594440

UnificationXref2120
type: UnificationXref
id: 5597090
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597090

UnificationXref2121
type: UnificationXref
id: REACT_193049
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_193049.3

UnificationXref2122
type: UnificationXref
id: 5596728
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596728

DNA polymerase epsilon:G-strand extended telomere end (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry678
component: DNA polymerase epsilon (name copied from entity in Homo sapiens)
xref: UnificationXref3861
cellular location: GO_0005654
comment: Reactome DB_ID: 5594532

RNA primer:G-strand extended telomere end:DNA polymerase alpha:primase complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry683
component stoichiometry: Stoichiometry681
component stoichiometry: Stoichiometry682
component: DNA polymerase alpha:primase (name copied from entity in Homo sapiens)
component: SmallMolecule521
component: PhysicalEntity18
xref: UnificationXref3866
cellular location: GO_0005654
comment: Reactome DB_ID: 5594534

RNA primer-DNA primer:G-strand extended telomere (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry684
component stoichiometry: Stoichiometry685
component: RNA primer:G-strand extended telomere end:DNA polymerase alpha:primase complex (name copied from entity in Homo sapiens)
component: PhysicalEntity17
xref: UnificationXref3869
cellular location: GO_0005654
comment: Reactome DB_ID: 5594536

RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry686
component stoichiometry: Stoichiometry688
component stoichiometry: Stoichiometry687
component stoichiometry: Stoichiometry689
component: RFC Heteropentamer (name copied from entity in Homo sapiens)
component: SmallMolecule521
component: PhysicalEntity17
component: PhysicalEntity18
xref: UnificationXref3874
cellular location: GO_0005654
comment: Reactome DB_ID: 5594538

PCNA homotrimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry673
component: Protein496
xref: UnificationXref3797
cellular location: GO_0005654
comment: Reactome DB_ID: 5593300

UnificationXref2127
type: UnificationXref
id: 5594442
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594442

RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry675
component stoichiometry: Stoichiometry674
component: RFC Heteropentamer:RNA primer-DNA primer:origin duplex (name copied from entity in Homo sapiens)
component: PCNA homotrimer (name copied from entity in Homo sapiens)
xref: UnificationXref3798
cellular location: GO_0005654
comment: Reactome DB_ID: 5593301

UnificationXref2128
type: UnificationXref
id: REACT_239019
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_239019.1

RNA primer-DNA primer:origin duplex:PCNA (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry677
component stoichiometry: Stoichiometry676
component: RNA primer-DNA primer:origin duplex (name copied from entity in Homo sapiens)
component: PCNA homotrimer (name copied from entity in Homo sapiens)
xref: UnificationXref3801
cellular location: GO_0005654
comment: Reactome DB_ID: 5593303

UnificationXref2129
type: UnificationXref
id: 5596861
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596861

DNA polymerase alpha:primase:DNA polymerase alpha:G-strand extended telomere end (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry679
component stoichiometry: Stoichiometry680
component: DNA polymerase alpha:primase (name copied from entity in Homo sapiens)
component: DNA polymerase epsilon:G-strand extended telomere end (name copied from entity in Homo sapiens)
xref: UnificationXref3862
cellular location: GO_0005654
comment: Reactome DB_ID: 5594533

http://identifiers.org/pubmed/12627223
type: PublicationXref
id: 12627223
author: Miyano, M
author: Irikura, Daisuke
author: Matsumura, H
author: Kumasaka, T
author: Kai, Y
author: Uodome, N
author: Urade, Y
author: Yamamoto, M
author: Inoue, T
author: Kinugasa, S
author: Okazaki, N
db: Pubmed
title: Mechanism of metal activation of human hematopoietic prostaglandin D synthase
source: Nat Struct Biol 10:291-6
year: 2003

UniProt:PFF0885w
type: ProteinReference
xref: UnificationXref3373
organism: http://identifiers.org/taxonomy/5833

RFC Heteropentamer:RNA primer-DNA primer:origin duplex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry672
component stoichiometry: Stoichiometry671
component: RFC Heteropentamer (name copied from entity in Homo sapiens)
component: RNA primer-DNA primer:origin duplex (name copied from entity in Homo sapiens)
xref: UnificationXref3794
cellular location: GO_0005654
comment: Reactome DB_ID: 5593293

RFC Heteropentamer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry666
component stoichiometry: Stoichiometry668
component stoichiometry: Stoichiometry667
component stoichiometry: Stoichiometry670
component stoichiometry: Stoichiometry669
component: Protein579
component: Protein581
component: Protein580
component: Protein583
component: Protein582
xref: UnificationXref3793
cellular location: GO_0005654
comment: Reactome DB_ID: 5593292

Mcm4,6,7 complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry665
component stoichiometry: Stoichiometry664
component stoichiometry: Stoichiometry663
component: Protein572
component: Protein574
component: Protein577
xref: UnificationXref3766
cellular location: GO_0005654
comment: Reactome DB_ID: 5593280

UnificationXref2114
type: UnificationXref
id: REACT_160371
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_160371.1

UnificationXref2115
type: UnificationXref
id: CHEBI:64183
db: ChEBI

http://identifiers.org/pubmed/8431482
type: PublicationXref
id: 8431482
author: Ahmad, H
author: Singhal, S S
author: Awasthi, Y C
author: Saxena, M
db: Pubmed
title: Characterization of two novel subunits of the alpha-class glutathione S-transferases of human liver
source: Biochim. Biophys. Acta 1161:333-6
year: 1993

UnificationXref2112
type: UnificationXref
id: CHEBI:64182
db: ChEBI

UnificationXref2113
type: UnificationXref
id: 2162212
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2162212

UnificationXref2110
type: UnificationXref
id: 5596306
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596306

UnificationXref2111
type: UnificationXref
id: REACT_207207
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_207207.2

ubiquitinated Cdc6 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry656
component stoichiometry: Stoichiometry655
component: Protein518
component: Protein571
xref: UnificationXref3748
cellular location: GO_0005829
comment: Reactome DB_ID: 5593278

http://identifiers.org/pubmed/18288277
type: PublicationXref
id: 18288277
author: Kersten, S
db: Pubmed
title: Peroxisome proliferator activated receptors and lipoprotein metabolism
source: PPAR Res 2008:132960
year: 2008

Mcm2-7 complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry657
component stoichiometry: Stoichiometry662
component stoichiometry: Stoichiometry661
component stoichiometry: Stoichiometry660
component stoichiometry: Stoichiometry659
component stoichiometry: Stoichiometry658
component: Protein572
component: Protein574
component: Protein573
component: Protein576
component: Protein575
component: Protein577
xref: UnificationXref3765
cellular location: GO_0005654
comment: Reactome DB_ID: 5593269

26S proteasome (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry649
component stoichiometry: Stoichiometry647
component stoichiometry: Stoichiometry629
component stoichiometry: Stoichiometry648
component stoichiometry: Stoichiometry627
component stoichiometry: Stoichiometry628
component stoichiometry: Stoichiometry625
component stoichiometry: Stoichiometry626
component stoichiometry: Stoichiometry641
component stoichiometry: Stoichiometry623
component stoichiometry: Stoichiometry642
component stoichiometry: Stoichiometry624
component stoichiometry: Stoichiometry621
component stoichiometry: Stoichiometry640
component stoichiometry: Stoichiometry622
component stoichiometry: Stoichiometry645
component stoichiometry: Stoichiometry646
component stoichiometry: Stoichiometry620
component stoichiometry: Stoichiometry643
component stoichiometry: Stoichiometry644
component stoichiometry: Stoichiometry618
component stoichiometry: Stoichiometry636
component stoichiometry: Stoichiometry619
component stoichiometry: Stoichiometry637
component stoichiometry: Stoichiometry638
component stoichiometry: Stoichiometry639
component stoichiometry: Stoichiometry614
component stoichiometry: Stoichiometry615
component stoichiometry: Stoichiometry616
component stoichiometry: Stoichiometry617
component stoichiometry: Stoichiometry630
component stoichiometry: Stoichiometry613
component stoichiometry: Stoichiometry631
component stoichiometry: Stoichiometry632
component stoichiometry: Stoichiometry633
component stoichiometry: Stoichiometry634
component stoichiometry: Stoichiometry635
component stoichiometry: Stoichiometry652
component stoichiometry: Stoichiometry651
component stoichiometry: Stoichiometry650
component: Protein554
component: Protein553
component: Protein556
component: Protein555
component: Protein550
component: Protein552
component: Protein551
component: Protein568
component: Protein530
component: Protein533
component: Protein546
component: Protein534
component: Protein547
component: Protein531
component: Protein548
component: Protein532
component: Protein549
component: Protein567
component: Protein536
component: Protein566
component: Protein535
component: Protein565
component: Protein538
component: Protein564
component: Protein537
component: Protein563
component: Protein562
component: Protein539
component: Protein561
component: Protein560
component: Protein540
component: Protein541
component: Protein559
component: Protein542
component: Protein543
component: Protein557
component: Protein544
component: Protein558

CDK (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry654
component stoichiometry: Stoichiometry653
component: Protein569
component: PhysicalEntity15
xref: UnificationXref3741
cellular location: GO_0005654
comment: Reactome DB_ID: 5593144

Gluconeogenesis
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction58
pathway component: BiochemicalReaction59
pathway component: BiochemicalReaction56
pathway component: BiochemicalReaction57
pathway component: BiochemicalReaction60
pathway component: BiochemicalReaction61
pathway component: BiochemicalReaction62
pathway component: BiochemicalReaction63
pathway component: BiochemicalReaction64
pathway component: BiochemicalReaction55
evidence: Evidence137
xref: UnificationXref818
xref: UnificationXref819
xref: RelationshipXref101
pathway order: PathwayStep129
pathway order: PathwayStep127
pathway order: PathwayStep128
pathway order: PathwayStep134
pathway order: PathwayStep126
pathway order: PathwayStep135
pathway order: PathwayStep130
pathway order: PathwayStep131
pathway order: PathwayStep132
pathway order: PathwayStep133
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref2118
type: UnificationXref
id: 5596302
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596302

ubiquitinated Orc1 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry610
component stoichiometry: Stoichiometry609
component: Protein507
component: Protein495
xref: UnificationXref3645
cellular location: GO_0005654
comment: Reactome DB_ID: 5593162

UnificationXref2119
type: UnificationXref
id: REACT_224281
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_224281.2

ubiquitinated Orc1 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry611
component stoichiometry: Stoichiometry612
component: Protein518
component: Protein529
xref: UnificationXref3660
cellular location: GO_0005829
comment: Reactome DB_ID: 5593176

UnificationXref2116
type: UnificationXref
id: 2162198
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2162198

UnificationXref2117
type: UnificationXref
id: REACT_161274
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_161274.1

RNA primer-DNA primer:origin duplex with DNA damage (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry608
component stoichiometry: Stoichiometry607
component: PhysicalEntity17
component: PhysicalEntity19
xref: UnificationXref3600
cellular location: GO_0005654
comment: Reactome DB_ID: 5594333

DNA polymerase epsilon (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry597
component stoichiometry: Stoichiometry598
component: Protein505
component: Protein504
xref: UnificationXref3583
cellular location: GO_0005654
comment: Reactome DB_ID: 5593134

DNA polymerase alpha:primase:DNA polymerase alpha:origin complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry601
component stoichiometry: Stoichiometry600
component: DNA polymerase epsilon:origin complex (name copied from entity in Homo sapiens)
component: DNA polymerase alpha:primase (name copied from entity in Homo sapiens)
xref: UnificationXref3585
cellular location: GO_0005654
comment: Reactome DB_ID: 5593136

RNA primer-DNA primer:origin duplex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry602
component stoichiometry: Stoichiometry606
component: RNA primer:origin duplex:DNA polymerase alpha:primase complex (name copied from entity in Homo sapiens)
component: PhysicalEntity17
xref: UnificationXref3597
cellular location: GO_0005654
comment: Reactome DB_ID: 5593254

SHC1 events in ERBB2 signaling
type: Pathway
data source: Provenance1
pathway component: REACT 238671.1
evidence: Evidence790
xref: UnificationXref4615
xref: UnificationXref4616
pathway order: PathwayStep70
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

RNA primer:origin duplex:DNA polymerase alpha:primase complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry605
component stoichiometry: Stoichiometry604
component stoichiometry: Stoichiometry603
component: DNA polymerase alpha:primase (name copied from entity in Homo sapiens)
component: PhysicalEntity16
component: PhysicalEntity18
xref: UnificationXref3596
cellular location: GO_0005654
comment: Reactome DB_ID: 5593138

eIF2:GTP (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry585
component stoichiometry: Stoichiometry581
component: EIF2S1:EIF2S2:EIF2S3 (name copied from entity in Homo sapiens)
component: SmallMolecule326
xref: UnificationXref3539
cellular location: GO_0005829
comment: Reactome DB_ID: 5593683

ternary complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry586
component stoichiometry: Stoichiometry587
component: eIF2:GTP (name copied from entity in Homo sapiens)
component: PhysicalEntity13
xref: UnificationXref3542
cellular location: GO_0005829
comment: Reactome DB_ID: 5593684

phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry591
component stoichiometry: Stoichiometry590
component: 43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP (name copied from entity in Homo sapiens)
component: Protein446
xref: UnificationXref3545
cellular location: GO_0005829
comment: Reactome DB_ID: 5594375

EIF2S1:EIF2S2:EIF2S3 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry584
component stoichiometry: Stoichiometry583
component stoichiometry: Stoichiometry582
component: Protein492
component: Protein491
component: Protein490
xref: UnificationXref3538
cellular location: GO_0005829
comment: Reactome DB_ID: 5593682

DNA polymerase epsilon:origin complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry596
component stoichiometry: Stoichiometry599
component: DNA polymerase epsilon (name copied from entity in Homo sapiens)
component: PhysicalEntity16
xref: UnificationXref3584
cellular location: GO_0005654
comment: Reactome DB_ID: 5593135

DNA polymerase alpha:primase (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry595
component stoichiometry: Stoichiometry592
component stoichiometry: Stoichiometry594
component stoichiometry: Stoichiometry593
component: Protein499
component: PhysicalEntity15
component: Protein503
component: Protein502
xref: UnificationXref3576
cellular location: GO_0005654
comment: Reactome DB_ID: 5593129

Fibroblast Growth Factor Receptor (FGFR) signaling
type: Pathway
data source: Provenance1
pathway component: REACT 263387.1
evidence: Evidence88
xref: UnificationXref553
xref: UnificationXref552
xref: RelationshipXref69
pathway order: PathwayStep86
display name: Signaling by FGFR
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

43S complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry588
component stoichiometry: Stoichiometry570
component stoichiometry: Stoichiometry538
component stoichiometry: Stoichiometry580
component: ternary complex (name copied from entity in Homo sapiens)
component: Protein451
component: 40S ribosomal complex (name copied from entity in Homo sapiens)
component: eIF3 subunits complex (name copied from entity in Homo sapiens)
xref: UnificationXref3543
cellular location: GO_0005829
comment: Reactome DB_ID: 5593685

40S ribosomal complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry550
component stoichiometry: Stoichiometry549
component stoichiometry: Stoichiometry548
component stoichiometry: Stoichiometry545
component stoichiometry: Stoichiometry563
component stoichiometry: Stoichiometry544
component stoichiometry: Stoichiometry562
component stoichiometry: Stoichiometry565
component stoichiometry: Stoichiometry547
component stoichiometry: Stoichiometry564
component stoichiometry: Stoichiometry546
component stoichiometry: Stoichiometry567
component stoichiometry: Stoichiometry541
component stoichiometry: Stoichiometry566
component stoichiometry: Stoichiometry540
component stoichiometry: Stoichiometry569
component stoichiometry: Stoichiometry543
component stoichiometry: Stoichiometry568
component stoichiometry: Stoichiometry542
component stoichiometry: Stoichiometry560
component stoichiometry: Stoichiometry561
component stoichiometry: Stoichiometry559
component stoichiometry: Stoichiometry539
component stoichiometry: Stoichiometry554
component stoichiometry: Stoichiometry553
component stoichiometry: Stoichiometry552
component stoichiometry: Stoichiometry551
component stoichiometry: Stoichiometry558
component stoichiometry: Stoichiometry557
component stoichiometry: Stoichiometry556
component stoichiometry: Stoichiometry555
component: Protein459
component: Protein458
component: Protein465
component: Protein466
component: Protein467
component: Protein468
component: Protein480
component: Protein461
component: Protein462
component: Protein463
component: Protein481
component: Protein464
component: Protein460
component: Protein469
component: Protein456
component: Protein457
component: Protein454
component: Protein455
component: Protein452
component: Protein471
component: Protein453
component: Protein470
component: Protein475
component: Protein474
component: Protein473
component: Protein472
component: Protein479
component: Protein478
component: Protein477
component: PhysicalEntity2
component: Protein476
xref: UnificationXref3514
cellular location: GO_0005829
comment: Reactome DB_ID: 5593656

eIF4F (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry536
component stoichiometry: Stoichiometry535
component stoichiometry: Stoichiometry532
component: eIF4A subunits complex (name copied from entity in Homo sapiens)
component: PhysicalEntity2
component: Protein448
xref: UnificationXref3451
cellular location: GO_0005829
comment: Reactome DB_ID: 5593693

eIF4A subunits complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry534
component stoichiometry: Stoichiometry533
component: Protein450
component: Protein449
xref: UnificationXref3450
cellular location: GO_0005829
comment: Reactome DB_ID: 5593690

eIF3 subunits complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry579
component stoichiometry: Stoichiometry577
component stoichiometry: Stoichiometry578
component stoichiometry: Stoichiometry575
component stoichiometry: Stoichiometry576
component stoichiometry: Stoichiometry573
component stoichiometry: Stoichiometry571
component stoichiometry: Stoichiometry574
component stoichiometry: Stoichiometry572
component: Protein482
component: Protein484
component: Protein483
component: Protein486
component: Protein485
component: Protein488
component: Protein487
component: PhysicalEntity2
component: Protein489
xref: UnificationXref3531
cellular location: GO_0005829
comment: Reactome DB_ID: 5593673

Kinesins
type: Complex
data source: Provenance1
member physical entity: KIF18A dimer (name copied from entity in Homo sapiens)
member physical entity: Kinesin-5 homotetramer (name copied from entity in Homo sapiens)
xref: UnificationXref3333
cellular location: GO_0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5595840

43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry589
component stoichiometry: Stoichiometry537
component stoichiometry: Stoichiometry531
component stoichiometry: Stoichiometry530
component: 43S complex (name copied from entity in Homo sapiens)
component: eIF4F (name copied from entity in Homo sapiens)
component: PhysicalEntity2
component: Protein447
xref: UnificationXref3544
cellular location: GO_0005829
comment: Reactome DB_ID: 5594374

60s ribosomal complex lacking L13a subunit (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry520
component stoichiometry: Stoichiometry502
component stoichiometry: Stoichiometry521
component stoichiometry: Stoichiometry503
component stoichiometry: Stoichiometry500
component stoichiometry: Stoichiometry501
component stoichiometry: Stoichiometry524
component stoichiometry: Stoichiometry525
component stoichiometry: Stoichiometry522
component stoichiometry: Stoichiometry523
component stoichiometry: Stoichiometry528
component stoichiometry: Stoichiometry529
component stoichiometry: Stoichiometry486
component stoichiometry: Stoichiometry526
component stoichiometry: Stoichiometry487
component stoichiometry: Stoichiometry508
component stoichiometry: Stoichiometry527
component stoichiometry: Stoichiometry488
component stoichiometry: Stoichiometry509
component stoichiometry: Stoichiometry489
component stoichiometry: Stoichiometry506
component stoichiometry: Stoichiometry507
component stoichiometry: Stoichiometry504
component stoichiometry: Stoichiometry505
component stoichiometry: Stoichiometry497
component stoichiometry: Stoichiometry496
component stoichiometry: Stoichiometry491
component stoichiometry: Stoichiometry499
component stoichiometry: Stoichiometry498
component stoichiometry: Stoichiometry490
component stoichiometry: Stoichiometry493
component stoichiometry: Stoichiometry492
component stoichiometry: Stoichiometry495
component stoichiometry: Stoichiometry494
component stoichiometry: Stoichiometry510
component stoichiometry: Stoichiometry511
component stoichiometry: Stoichiometry512
component stoichiometry: Stoichiometry513
component stoichiometry: Stoichiometry514
component stoichiometry: Stoichiometry515
component stoichiometry: Stoichiometry516
component stoichiometry: Stoichiometry517
component stoichiometry: Stoichiometry518
component stoichiometry: Stoichiometry519
component: Protein399
component: Protein398
component: Protein437
component: Protein424
component: Protein423
component: Protein422
component: Protein438
component: Protein421
component: Protein402
component: Protein420
component: Protein401
component: Protein400
component: Protein441
component: Protein418
component: Protein442
component: Protein419
component: Protein443
component: Protein416
component: Protein417
component: Protein414
component: Protein415
component: Protein428
component: Protein411
component: Protein427
component: Protein410
component: Protein426
component: Protein413
component: Protein425
component: Protein412
component: Protein429
component: Protein430
component: Protein407
component: Protein431
component: Protein408

http://identifiers.org/pubmed/17132626
type: PublicationXref
id: 17132626
author: Forman, HJ
author: Persechini, PM
author: Ojcius, DM
author: Ventura, AL
author: Rinna, A
author: Cruz, CM
db: Pubmed
title: ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
source: J Biol Chem 282:2871-9
year: 2007

60S ribosomal complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry442
component stoichiometry: Stoichiometry441
component stoichiometry: Stoichiometry444
component stoichiometry: Stoichiometry443
component stoichiometry: Stoichiometry446
component stoichiometry: Stoichiometry445
component stoichiometry: Stoichiometry448
component stoichiometry: Stoichiometry447
component stoichiometry: Stoichiometry485
component stoichiometry: Stoichiometry467
component stoichiometry: Stoichiometry468
component stoichiometry: Stoichiometry449
component stoichiometry: Stoichiometry469
component stoichiometry: Stoichiometry463
component stoichiometry: Stoichiometry464
component stoichiometry: Stoichiometry465
component stoichiometry: Stoichiometry466
component stoichiometry: Stoichiometry471
component stoichiometry: Stoichiometry470
component stoichiometry: Stoichiometry473
component stoichiometry: Stoichiometry472
component stoichiometry: Stoichiometry450
component stoichiometry: Stoichiometry451
component stoichiometry: Stoichiometry476
component stoichiometry: Stoichiometry458
component stoichiometry: Stoichiometry477
component stoichiometry: Stoichiometry459
component stoichiometry: Stoichiometry474
component stoichiometry: Stoichiometry456
component stoichiometry: Stoichiometry475
component stoichiometry: Stoichiometry457
component stoichiometry: Stoichiometry454
component stoichiometry: Stoichiometry455
component stoichiometry: Stoichiometry478
component stoichiometry: Stoichiometry452
component stoichiometry: Stoichiometry479
component stoichiometry: Stoichiometry453
component stoichiometry: Stoichiometry480
component stoichiometry: Stoichiometry462
component stoichiometry: Stoichiometry461
component stoichiometry: Stoichiometry460
component stoichiometry: Stoichiometry484
component stoichiometry: Stoichiometry483
component stoichiometry: Stoichiometry482
component stoichiometry: Stoichiometry481
component: Protein399
component: Protein398
component: Protein437
component: Protein424
component: Protein436
component: Protein423
component: Protein422
component: Protein438
component: Protein421
component: Protein402
component: Protein420
component: Protein401
component: Protein400
component: Protein441
component: Protein418
component: Protein442
component: Protein419
component: Protein443
component: Protein416
component: Protein417
component: Protein414
component: Protein415
component: Protein428
component: Protein411
component: Protein427
component: Protein410
component: Protein426
component: Protein413
component: Protein425
component: Protein412
component: Protein429
component: Protein430
component: Protein407

Kinesins:microtubule (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry439
component stoichiometry: Stoichiometry440
component: Kinesins
component: PhysicalEntity12
xref: UnificationXref3334
cellular location: GO_0005829
comment: Reactome DB_ID: 5595841

http://identifiers.org/pubmed/15877282
type: PublicationXref
id: 15877282
author: Eshhar, S
author: Elpeleg, O
author: Saada, A
author: Miller, C
author: Bondi-Rubinstein, G
author: Pagnamenta, A
author: Rahman, S
author: Bitner-Glindzicz, M
author: Hershkovitz, E
db: Pubmed
title: Deficiency of the ADP-forming succinyl-CoA synthase activity is associated with encephalomyopathy and mitochondrial DNA depletion
source: Am J Hum Genet 76:1081-6
year: 2005

http://identifiers.org/pubmed/11909533
type: PublicationXref
id: 11909533
author: Ho, MW
author: Vogel, G
author: Shears, Stephen B
author: Chung, SK
author: Carew, MA
author: Kwon, YU
author: Riley, AM
author: Hua, L
author: Yang, X
author: Adelt, S
author: Potter, BV
author: Zhang, T
db: Pubmed
title: Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase
source: Curr Biol 12:477-82
year: 2002

http://identifiers.org/pubmed/20192774
type: PublicationXref
id: 20192774
author: Leventis, PA
author: Grinstein, S
db: Pubmed
title: The distribution and function of phosphatidylserine in cellular membranes
source: Annu Rev Biophys 39:407-27
year: 2010

KIF18A dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry436
component: Protein396
xref: UnificationXref3324
cellular location: GO_0005829
comment: Reactome DB_ID: 5595839

Kinesin-14 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry438
component: Protein397
xref: UnificationXref3329
cellular location: GO_0005829
comment: Reactome DB_ID: 5595848

14-3-3zeta dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry428
component: Protein377
xref: UnificationXref3263
cellular location: GO_0005829
comment: Reactome DB_ID: 5595407

http://identifiers.org/pubmed/12670391
type: PublicationXref
id: 12670391
author: Kane, LP
author: Weiss, A
db: Pubmed
title: The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3
source: Immunol Rev 192:7-20
year: 2003

14-3-3-zeta:Raf1 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry430
component stoichiometry: Stoichiometry429
component: Protein378
component: 14-3-3zeta dimer (name copied from entity in Homo sapiens)
xref: UnificationXref3265
cellular location: GO_0005829
comment: Reactome DB_ID: 5595448

UniProt:PFC0710w.1
type: ProteinReference
xref: UnificationXref5601
organism: http://identifiers.org/taxonomy/5833

F-actin capping protein (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry432
component stoichiometry: Stoichiometry431
component: Protein393
component: Protein394
xref: UnificationXref3314
cellular location: GO_0005829
comment: Reactome DB_ID: 5595720

UniProt:PFC0710w.2
type: ProteinReference
xref: UnificationXref5599
organism: http://identifiers.org/taxonomy/5833

Kinesin-5 homotetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry434
component: Protein395
xref: UnificationXref3319
cellular location: GO_0005829
comment: Reactome DB_ID: 5595836

DSIF complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry422
component stoichiometry: Stoichiometry421
component: Protein365
component: Protein364
xref: UnificationXref3206
cellular location: GO_0005654
comment: Reactome DB_ID: 5594331

HMGB1/HMGB2- bound chromatin (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry420
component stoichiometry: Stoichiometry419
component: PhysicalEntity11
component: Protein359
xref: UnificationXref3185
cellular location: GO_0005654
comment: Reactome DB_ID: 5594974

Activated cGMP-dependent protein kinase (PKGs) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry426
component stoichiometry: Stoichiometry427
component: Protein369
component: SmallMolecule510
xref: UnificationXref3237
cellular location: GO_0005829
comment: Reactome DB_ID: 5595260

FACT complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry424
component stoichiometry: Stoichiometry423
component: Protein367
component: Protein366
xref: UnificationXref3213
cellular location: GO_0005654
comment: Reactome DB_ID: 5594321

http://identifiers.org/pubmed/8163052
type: PublicationXref
id: 8163052
author: Gomis, R
author: Malaisse, WJ
author: Sener, A
author: Fernandez-Alvarez, J
author: Conget, I
author: Rasschaert, J
db: Pubmed
title: Enzymatic, metabolic and secretory patterns in human islets of type 2 (non-insulin-dependent) diabetic patients
source: Diabetologia 37:177-81
year: 1994

http://identifiers.org/pubmed/15080793
type: PublicationXref
id: 15080793
author: Wenk, MR
author: De Camilli, Pietro
author: Uhlén, P
author: Lee, E
author: Ehrlich, BE
author: Degray, B
author: Johenning, FW
db: Pubmed
title: InsP3-mediated intracellular calcium signalling is altered by expression of synaptojanin-1
source: Biochem J 382:687-94
year: 2004

UniProt:PFL0310c
type: ProteinReference
xref: UnificationXref3527
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/15105273
type: PublicationXref
id: 15105273
author: Westaway, SK
author: Johnson, MA
author: Parker, SM
author: Hayflick, SJ
author: Gitschier, J
author: Ching, KH
author: Kuo, YM
db: Pubmed
title: Mitochondrial localization of human PANK2 and hypotheses of secondary iron accumulation in pantothenate kinase-associated neurodegeneration
source: Ann N Y Acad Sci 1012:282-98
year: 2004

http://identifiers.org/pubmed/9889196
type: PublicationXref
id: 9889196
author: Sørensen, CS
author: Lukas, J
author: Petersen, BO
author: Helin, K
db: Pubmed
title: Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization.
source: EMBO J 18:396-410
year: 1999

FDX1L (reduced) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry415
component stoichiometry: Stoichiometry416
component: Protein356
component: SmallMolecule505
xref: UnificationXref3144
cellular location: GO_0005759
comment: Reactome DB_ID: 5596340

FDXR:FADH2 (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry411
component stoichiometry: Stoichiometry410
component: SmallMolecule208
component: Protein355
xref: UnificationXref3132
cellular location: GO_0005759
comment: Reactome DB_ID: 5596335

FDX1L (oxidized) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry413
component stoichiometry: Stoichiometry412
component: Protein356
component: SmallMolecule504
xref: UnificationXref3140
cellular location: GO_0005759
comment: Reactome DB_ID: 5596338

AKR7L dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry407
component: Protein354
xref: UnificationXref3121
cellular location: GO_0005829
comment: Reactome DB_ID: 5596638

FDXR:FAD (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry408
component stoichiometry: Stoichiometry409
component: Protein355
component: SmallMolecule206
xref: UnificationXref3131
cellular location: GO_0005759
comment: Reactome DB_ID: 5596339

AKR7A2 dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry405
component: Protein352
xref: UnificationXref3116
cellular location: GO_0005829
comment: Reactome DB_ID: 5596633

AKR7A3 dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry406
component: Protein353
xref: UnificationXref3119
cellular location: GO_0005829
comment: Reactome DB_ID: 5596636

AKR dimers
type: Complex
data source: Provenance1
member physical entity: AKR7L dimer (name copied from entity in Homo sapiens)
member physical entity: AKR7A2 dimer (name copied from entity in Homo sapiens)
member physical entity: AKR7A3 dimer (name copied from entity in Homo sapiens)
xref: UnificationXref3122
cellular location: GO_0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5596639

2xHPGDS (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry404
component: Protein248
xref: UnificationXref3100
cellular location: GO_0005829
comment: Reactome DB_ID: 5594554

GST dimers
type: Complex
data source: Provenance1
member physical entity: 2xHPGDS (name copied from entity in Homo sapiens)
xref: UnificationXref3101
cellular location: GO_0005829
comment: Reactome DB_ID: 5594555
comment: Converted from EntitySet in Reactome

http://identifiers.org/pubmed/14990995
type: PublicationXref
id: 14990995
author: Yoshida, K
author: Inoue, I
db: Pubmed
title: Regulation of Geminin and Cdt1 expression by E2F transcription factors
source: Oncogene 23:3802-12
year: 2004

UnificationXref5882
type: UnificationXref
id: GO:0030660
db: GENE ONTOLOGY

UnificationXref5881
type: UnificationXref
id: 5594800
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594800

UnificationXref5884
type: UnificationXref
id: 5594810
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594810

UnificationXref5883
type: UnificationXref
id: 5594809
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594809

UnificationXref5886
type: UnificationXref
id: 5594796
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594796

UnificationXref5885
type: UnificationXref
id: REACT_230103
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_230103.1

UnificationXref5888
type: UnificationXref
id: REACT_259512
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_259512.1

UnificationXref5887
type: UnificationXref
id: 5594798
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594798

UnificationXref5889
type: UnificationXref
id: 5594801
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594801

http://identifiers.org/pubmed/12482742
type: PublicationXref
id: 12482742
author: Busse, R
author: Fleming, I
db: Pubmed
title: Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase
source: Am J Physiol Regul Integr Comp Physiol 284:R1-12
year: 2003

http://identifiers.org/pubmed/6434529
type: PublicationXref
id: 6434529
author: Chuang, DT
author: Cox, RP
author: Markovitz, PJ
db: Pubmed
title: Familial hyperlysinemias. Purification and characterization of the bifunctional aminoadipic semialdehyde synthase with lysine-ketoglutarate reductase and saccharopine dehydrogenase activities.
source: J Biol Chem 259:11643-6
year: 1984

UnificationXref5880
type: UnificationXref
id: REACT_250981
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_250981.1

UnificationXref5895
type: UnificationXref
id: 5596924
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596924

http://identifiers.org/pubmed/19165215
type: PublicationXref
id: 19165215
author: Siomi, MC
author: Kim, VN
author: Han, J
db: Pubmed
title: Biogenesis of small RNAs in animals
source: Nat Rev Mol Cell Biol 10:126-39
year: 2009

UnificationXref5894
type: UnificationXref
id: REACT_251527
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_251527.1

UnificationXref5893
type: UnificationXref
id: 5594814
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594814

UnificationXref5892
type: UnificationXref
id: REACT_226267
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_226267.2

UnificationXref5899
type: UnificationXref
id: 5596926
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596926

Downstream signal transduction
type: Pathway
data source: Provenance1
pathway component: REACT 237994.1
pathway component: REACT 238671.1
pathway component: REACT 259160.1
evidence: Evidence783
xref: UnificationXref4601
xref: UnificationXref4602
pathway order: PathwayStep70
pathway order: PathwayStep66
pathway order: PathwayStep77
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref5898
type: UnificationXref
id: REACT_251802
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_251802.1

UnificationXref5897
type: UnificationXref
id: 5596925
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596925

UnificationXref5896
type: UnificationXref
id: REACT_246577
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_246577.1

http://identifiers.org/pubmed/8946167
type: PublicationXref
id: 8946167
author: Blanch, L
author: Anson, D S
author: Hopwood, J J
author: Scott, H S
author: Guo, X H
author: Karageorgos, L E
author: Weber, B
db: Pubmed
title: Structure and sequence of the human sulphamidase gene
source: DNA Res. 3:269-71
year: 1996

Stoichiometry597
type: Stoichiometry
physical entity: Protein504
stoichiometric coefficient: 1.0

Stoichiometry598
type: Stoichiometry
physical entity: Protein505
stoichiometric coefficient: 1.0

Stoichiometry595
type: Stoichiometry
physical entity: Protein499
stoichiometric coefficient: 1.0

Stoichiometry596
type: Stoichiometry
physical entity: PhysicalEntity16
stoichiometric coefficient: 1.0

Stoichiometry599
type: Stoichiometry
physical entity: DNA polymerase epsilon (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Resolution of D-loop structures
type: Pathway
data source: Provenance1
pathway component: REACT 246414.1
evidence: Evidence685
xref: UnificationXref4210
xref: UnificationXref4209
pathway order: PathwayStep668
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref5890
type: UnificationXref
id: 5594802
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594802

UnificationXref5891
type: UnificationXref
id: 5594803
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594803

http://identifiers.org/pubmed/8228618
type: PublicationXref
id: 8228618
author: Brown, EJ
author: Lefkowith, JB
author: Bromley, FA
author: Lennartz, MR
db: Pubmed
title: Immunoglobulin G-mediated phagocytosis activates a calcium-independent, phosphatidylethanolamine-specific phospholipase
source: J Leukoc Biol 54:389-98
year: 1993

http://identifiers.org/pubmed/10748114
type: PublicationXref
id: 10748114
author: You, Z
author: Kitagawa, M
author: Komamura-Kohno, Y
author: Ishimi, Y
author: Omori, A
db: Pubmed
title: Inhibition of Mcm4,6,7 helicase activity by phosphorylation with cyclin A/Cdk2.
source: J Biol Chem 275:16235-41
year: 2000

Stoichiometry592
type: Stoichiometry
physical entity: Protein502
stoichiometric coefficient: 1.0

Stoichiometry591
type: Stoichiometry
physical entity: 43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry594
type: Stoichiometry
physical entity: PhysicalEntity15
stoichiometric coefficient: 1.0

Stoichiometry593
type: Stoichiometry
physical entity: Protein503
stoichiometric coefficient: 1.0

Stoichiometry590
type: Stoichiometry
physical entity: Protein446
stoichiometric coefficient: 1.0

Stoichiometry588
type: Stoichiometry
physical entity: ternary complex (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry589
type: Stoichiometry
physical entity: 43S complex (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/1104615
type: PublicationXref
id: 1104615
author: Adams, SL
author: Anderson, WF
author: Safer, B
author: Merrick, WC
db: Pubmed
title: Binding of MET-TRNAf and GTP to homogeneous initiation factor MP.
source: J Biol Chem 250:9076-82
year: 1976

Stoichiometry584
type: Stoichiometry
physical entity: Protein492
stoichiometric coefficient: 1.0

Stoichiometry585
type: Stoichiometry
physical entity: EIF2S1:EIF2S2:EIF2S3 (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry586
type: Stoichiometry
physical entity: eIF2:GTP (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry587
type: Stoichiometry
physical entity: PhysicalEntity13
stoichiometric coefficient: 1.0

UnificationXref4301
type: UnificationXref
id: MAL7P1.145
db: UniProt

UnificationXref4302
type: UnificationXref
id: 5596587
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596587

UnificationXref4303
type: UnificationXref
id: PF11_0184
db: UniProt

UnificationXref4304
type: UnificationXref
id: 5596585
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596585

UnificationXref4300
type: UnificationXref
id: REACT_244621
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_244621.1

UnificationXref4309
type: UnificationXref
id: 5358526
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5358526

Stoichiometry583
type: Stoichiometry
physical entity: Protein491
stoichiometric coefficient: 1.0

Stoichiometry582
type: Stoichiometry
physical entity: Protein490
stoichiometric coefficient: 1.0

Stoichiometry581
type: Stoichiometry
physical entity: SmallMolecule326
stoichiometric coefficient: 1.0

Stoichiometry580
type: Stoichiometry
physical entity: eIF3 subunits complex (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

UnificationXref4305
type: UnificationXref
id: 5596588
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596588

UnificationXref4306
type: UnificationXref
id: 5596598
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596598

UnificationXref4307
type: UnificationXref
id: 5596599
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596599

UnificationXref4308
type: UnificationXref
id: REACT_252214
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_252214.1

Stoichiometry579
type: Stoichiometry
physical entity: Protein489
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/9490415
type: PublicationXref
id: 9490415
author: Phillips, JH
author: Lanier, LL
author: Leong, C
author: Wu, J
author: Corliss, BC
db: Pubmed
title: Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells
source: Nature 391:703-7
year: 1998

Stoichiometry577
type: Stoichiometry
physical entity: Protein487
stoichiometric coefficient: 1.0

Stoichiometry578
type: Stoichiometry
physical entity: Protein488
stoichiometric coefficient: 1.0

Stoichiometry575
type: Stoichiometry
physical entity: PhysicalEntity2
stoichiometric coefficient: 3.0

http://identifiers.org/pubmed/8755247
type: PublicationXref
id: 8755247
author: Migliaccio, E
author: Bonfini, L
author: Pelicci, PG
author: Pelicci, G
author: Lanfrancone, L
db: Pubmed
title: Not all Shc's roads lead to Ras
source: Trends Biochem Sci 21:257-61
year: 1996

Stoichiometry576
type: Stoichiometry
physical entity: Protein486
stoichiometric coefficient: 1.0

Stoichiometry573
type: Stoichiometry
physical entity: Protein484
stoichiometric coefficient: 1.0

Stoichiometry574
type: Stoichiometry
physical entity: Protein485
stoichiometric coefficient: 1.0

AHCY:NAD+ (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry375
component stoichiometry: Stoichiometry374
component: SmallMolecule81
component: Protein340
xref: UnificationXref2932
cellular location: GO_0005829
comment: Reactome DB_ID: 5594528

4x(AHCY:NAD+) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry376
component: AHCY:NAD+ (name copied from entity in Homo sapiens)
xref: UnificationXref2933
cellular location: GO_0005829
comment: Reactome DB_ID: 5594529

MAT I homotetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry370
component: MAT I/III (Mg, K cofactors) (name copied from entity in Homo sapiens)
xref: UnificationXref2920
cellular location: GO_0005829
comment: Reactome DB_ID: 5594515

MAT multimers
type: Complex
data source: Provenance1
member physical entity: MAT I homotetramer (name copied from entity in Homo sapiens)
member physical entity: MAT III homodimer (name copied from entity in Homo sapiens)
xref: UnificationXref2922
cellular location: GO_0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5594517

Stoichiometry570
type: Stoichiometry
physical entity: 40S ribosomal complex (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

MAT III homodimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry372
component stoichiometry: Stoichiometry371
component stoichiometry: Stoichiometry373
component: Protein339
component: SmallMolecule100
component: SmallMolecule96
xref: UnificationXref2921
cellular location: GO_0005829
comment: Reactome DB_ID: 5594516

Stoichiometry571
type: Stoichiometry
physical entity: Protein482
stoichiometric coefficient: 1.0

MAT I/III (Mg, K cofactors) (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry367
component stoichiometry: Stoichiometry368
component stoichiometry: Stoichiometry369
component: Protein339
component: SmallMolecule100
component: SmallMolecule96
xref: UnificationXref2919
cellular location: GO_0005829
comment: Reactome DB_ID: 5594514

Stoichiometry572
type: Stoichiometry
physical entity: Protein483
stoichiometric coefficient: 1.0

OTC trimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry362
component: Protein332
xref: UnificationXref2837
cellular location: GO_0005759
comment: Reactome DB_ID: 5593397

branched-chain alpha-ketoacid dehydrogenase E1 complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry356
component stoichiometry: Stoichiometry357
component stoichiometry: Stoichiometry358
component: SmallMolecule334
component: Protein329
component: Protein328
xref: UnificationXref2795
cellular location: GO_0005759
comment: Reactome DB_ID: 5593461

http://identifiers.org/pubmed/22119861
type: PublicationXref
id: 22119861
author: Hall, Traci M Tanaka
author: Falck, JR
author: Shears, Stephen B
author: Wang, Huanchen
db: Pubmed
title: Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding
source: Nat. Chem. Biol. 8:111-6
year: 2012

ARG2 trimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry365
component stoichiometry: Stoichiometry366
component: SmallMolecule339
component: Protein334
xref: UnificationXref2852
cellular location: GO_0005759
comment: Reactome DB_ID: 5595552

ARG1 trimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry364
component stoichiometry: Stoichiometry363
component: SmallMolecule26
component: Protein333
xref: UnificationXref2844
cellular location: GO_0005829
comment: Reactome DB_ID: 5593402

Stoichiometry563
type: Stoichiometry
physical entity: Protein475
stoichiometric coefficient: 1.0

Stoichiometry562
type: Stoichiometry
physical entity: Protein474
stoichiometric coefficient: 1.0

Stoichiometry565
type: Stoichiometry
physical entity: Protein477
stoichiometric coefficient: 1.0

Stoichiometry564
type: Stoichiometry
physical entity: Protein476
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/9469823
type: PublicationXref
id: 9469823
author: Watanabe, H
author: Gu, L
author: Hong, Y
author: Li, G M
author: McCulloch, S
db: Pubmed
title: ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair
source: Nucleic Acids Res. 26:1173-8
year: 1998

Stoichiometry567
type: Stoichiometry
physical entity: Protein479
stoichiometric coefficient: 1.0

Stoichiometry566
type: Stoichiometry
physical entity: Protein478
stoichiometric coefficient: 1.0

Stoichiometry569
type: Stoichiometry
physical entity: Protein481
stoichiometric coefficient: 1.0

Stoichiometry568
type: Stoichiometry
physical entity: Protein480
stoichiometric coefficient: 1.0

Stoichiometry560
type: Stoichiometry
physical entity: Protein472
stoichiometric coefficient: 1.0

Stoichiometry561
type: Stoichiometry
physical entity: Protein473
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/11742412
type: PublicationXref
id: 11742412
author: Saltiel, AR
author: Kahn, CR
db: Pubmed
title: Insulin signalling and the regulation of glucose and lipid metabolism
source: Nature 414:799-806
year: 2001

8-oxoguanine [ChEBI:29116]
type: SmallMoleculeReference
name: 8-oxoguanine
xref: UnificationXref4096

http://identifiers.org/pubmed/18660845
type: PublicationXref
id: 18660845
author: Zhao, FQ
author: Keating, AF
db: Pubmed
title: Functional properties and genomics of glucose transporters
source: Curr Genomics 8:113-28
year: 2007

Stoichiometry559
type: Stoichiometry
physical entity: Protein471
stoichiometric coefficient: 1.0

Stoichiometry554
type: Stoichiometry
physical entity: Protein467
stoichiometric coefficient: 1.0

Stoichiometry553
type: Stoichiometry
physical entity: Protein466
stoichiometric coefficient: 1.0

Stoichiometry552
type: Stoichiometry
physical entity: Protein465
stoichiometric coefficient: 1.0

Stoichiometry551
type: Stoichiometry
physical entity: Protein464
stoichiometric coefficient: 1.0

Stoichiometry558
type: Stoichiometry
physical entity: Protein470
stoichiometric coefficient: 1.0

Stoichiometry557
type: Stoichiometry
physical entity: Protein469
stoichiometric coefficient: 1.0

Stoichiometry556
type: Stoichiometry
physical entity: PhysicalEntity2
stoichiometric coefficient: 3.0

Stoichiometry555
type: Stoichiometry
physical entity: Protein468
stoichiometric coefficient: 1.0

CTPS2 tetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry333
component: Protein309
xref: UnificationXref2546
cellular location: GO_0005829
comment: Reactome DB_ID: 5595587

CTPS tetramer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry332
component: Protein308
xref: UnificationXref2542
cellular location: GO_0005829
comment: Reactome DB_ID: 5593892

ribonucleotide reductase M1 polypeptide dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry334
component: Protein312
xref: UnificationXref2563
cellular location: GO_0005829
comment: Reactome DB_ID: 5594280

ribonucleotide reductase (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry338
component stoichiometry: Stoichiometry335
component: ribonucleotide reductase M1 polypeptide dimer (name copied from entity in Homo sapiens)
component: ribonucleotide reductase M2 polypeptide dimer (name copied from entity in Homo sapiens)
xref: UnificationXref2570
cellular location: GO_0005829
comment: Reactome DB_ID: 5594284

Stoichiometry550
type: Stoichiometry
physical entity: Protein463
stoichiometric coefficient: 1.0

ribonucleotide reductase M2B (TP53 inducible) variant (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry343
component stoichiometry: Stoichiometry341
component: ribonucleotide reductase M1 polypeptide dimer (name copied from entity in Homo sapiens)
component: ribonucleotide reductase M2B (TP53 inducible) dimer (name copied from entity in Homo sapiens)
xref: UnificationXref2608
cellular location: GO_0005654
comment: Reactome DB_ID: 5594304

ribonucleotide reductase M2 polypeptide dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry337
component stoichiometry: Stoichiometry336
component: SmallMolecule391
component: Protein313
xref: UnificationXref2569
cellular location: GO_0005829
comment: Reactome DB_ID: 5594283

ribonucleotide reductase M1 polypeptide dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry342
component: Protein319
xref: UnificationXref2607
cellular location: GO_0005654
comment: Reactome DB_ID: 5594301

ribonucleotide reductase M2B (TP53 inducible) dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry340
component stoichiometry: Stoichiometry339
component: Protein318
component: SmallMolecule402
xref: UnificationXref2605
cellular location: GO_0005654
comment: Reactome DB_ID: 5594303

deoxythymidylate kinase (thymidylate kinase) holoenzyme (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry331
component: Protein307
xref: UnificationXref2532
cellular location: GO_0005829
comment: Reactome DB_ID: 5593877

TS dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry328
component stoichiometry: Stoichiometry327
component: Protein303
component: SmallMolecule96
xref: UnificationXref2485
cellular location: GO_0005829
comment: Reactome DB_ID: 5593869

http://identifiers.org/pubmed/17690096
type: PublicationXref
id: 17690096
author: York, JD
author: Otto, JC
author: Dollins, DE
author: Fridy, PC
db: Pubmed
title: Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases
source: J Biol Chem 282:30754-62
year: 2007

Stoichiometry549
type: Stoichiometry
physical entity: Protein462
stoichiometric coefficient: 1.0

Stoichiometry548
type: Stoichiometry
physical entity: Protein461
stoichiometric coefficient: 1.0

Stoichiometry545
type: Stoichiometry
physical entity: Protein458
stoichiometric coefficient: 1.0

Stoichiometry544
type: Stoichiometry
physical entity: Protein457
stoichiometric coefficient: 1.0

Stoichiometry547
type: Stoichiometry
physical entity: Protein460
stoichiometric coefficient: 2.0

Stoichiometry546
type: Stoichiometry
physical entity: Protein459
stoichiometric coefficient: 1.0

Stoichiometry541
type: Stoichiometry
physical entity: Protein454
stoichiometric coefficient: 1.0

Stoichiometry540
type: Stoichiometry
physical entity: Protein453
stoichiometric coefficient: 1.0

Stoichiometry543
type: Stoichiometry
physical entity: Protein456
stoichiometric coefficient: 1.0

Stoichiometry542
type: Stoichiometry
physical entity: Protein455
stoichiometric coefficient: 1.0

PYCR1 decamer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry353
component: Protein325
xref: UnificationXref2739
cellular location: GO_0005759
comment: Reactome DB_ID: 5593446

OAT hexamer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry352
component: Protein324
xref: UnificationXref2726
cellular location: GO_0005759
comment: Reactome DB_ID: 5593441

ITPA dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry351
component: Protein323
xref: UnificationXref2691
cellular location: GO_0005829
comment: Reactome DB_ID: 5596360

NME4 hexamer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry350
component: Protein322
xref: UnificationXref2679
cellular location: GO_0005743
comment: Reactome DB_ID: 5595582

http://identifiers.org/pubmed/12669019
type: PublicationXref
id: 12669019
author: Desjardins, M
db: Pubmed
title: ER-mediated phagocytosis: a new membrane for new functions
source: Nat Rev Immunol 3:280-91
year: 2003

branched-chain alpha-ketoacid dehydrogenase complex (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry359
component stoichiometry: Stoichiometry361
component stoichiometry: Stoichiometry360
component: alpha-keto acid dehydrogenase E3 homodimer (name copied from entity in Homo sapiens)
component: branched-chain alpha-ketoacid dehydrogenase E1 complex (name copied from entity in Homo sapiens)
component: Protein330
xref: UnificationXref2798
cellular location: GO_0005759
comment: Reactome DB_ID: 5593469

ChEBI:29265 Asn-tRNA(Asn)
type: SmallMoleculeReference
name: Asn-tRNA(Asn)
xref: UnificationXref4810

GLUD1 hexamer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry355
component: Protein327
xref: UnificationXref2756
cellular location: GO_0005759
comment: Reactome DB_ID: 5593414

ASNS dimer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry354
component: Protein326
xref: UnificationXref2747
cellular location: GO_0005829
comment: Reactome DB_ID: 5593431

L-Apple acid
type: SmallMoleculeReference
name: (S)-Malate [ChEBI:30797]
name: (S)-Malate
name: L-Malate
name: L-2-Hydroxybutanedioic acid
name: L-Malic acid
xref: UnificationXref779

nucleoside diphosphate kinase 1A:5B heterohexamer (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry349
component: Protein321
xref: UnificationXref2641
cellular location: GO_0005829
comment: Reactome DB_ID: 5595566

2xTXNRD1:2xFAD (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry347
component stoichiometry: Stoichiometry348
component: Protein203
component: SmallMolecule135
xref: UnificationXref2620
cellular location: GO_0005829
comment: Reactome DB_ID: 5593887

2xGSR-2:2xFAD (name copied from entity in Homo sapiens)
type: Complex
data source: Provenance1
component stoichiometry: Stoichiometry346
component stoichiometry: Stoichiometry345
component: SmallMolecule135
component: Protein320
xref: UnificationXref2615
cellular location: GO_0005829
comment: Reactome DB_ID: 5593575

Stoichiometry539
type: Stoichiometry
physical entity: Protein452
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/6434534
type: PublicationXref
id: 6434534
author: Gracy, RW
author: Yuan, PM
author: Lu, HS
db: Pubmed
title: Primary structure of human triosephosphate isomerase
source: J Biol Chem 259:11958-68
year: 1984

Stoichiometry538
type: Stoichiometry
physical entity: Protein451
stoichiometric coefficient: 1.0

Stoichiometry537
type: Stoichiometry
physical entity: eIF4F (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry536
type: Stoichiometry
physical entity: PhysicalEntity2
stoichiometric coefficient: 1.0

Stoichiometry535
type: Stoichiometry
physical entity: eIF4A subunits complex (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry534
type: Stoichiometry
physical entity: Protein450
stoichiometric coefficient: 1.0

Stoichiometry533
type: Stoichiometry
physical entity: Protein449
stoichiometric coefficient: 1.0

Stoichiometry532
type: Stoichiometry
physical entity: Protein448
stoichiometric coefficient: 1.0

Stoichiometry531
type: Stoichiometry
physical entity: Protein447
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/15274629
type: PublicationXref
id: 15274629
author: Takeuchi, N
author: Heck, A
author: Spencer, AC
author: Watanabe, K
author: Spremulli, LL
db: Pubmed
title: Characterization of the human mitochondrial methionyl-tRNA synthetase
source: Biochemistry 43:9743-54
year: 2004

Stoichiometry530
type: Stoichiometry
physical entity: PhysicalEntity2
stoichiometric coefficient: 3.0

http://identifiers.org/pubmed/7354069
type: PublicationXref
id: 7354069
author: Anderson, PM
author: Desnick, RJ
db: Pubmed
title: Purification and properties of uroporphyrinogen I synthase from human erythrocytes. Identification of stable enzyme-substrate intermediates.
source: J Biol Chem 255:1993-9
year: 1980

Stoichiometry520
type: Stoichiometry
physical entity: Protein431
stoichiometric coefficient: 1.0

Stoichiometry521
type: Stoichiometry
physical entity: Protein432
stoichiometric coefficient: 1.0

Stoichiometry524
type: Stoichiometry
physical entity: Protein435
stoichiometric coefficient: 1.0

Stoichiometry525
type: Stoichiometry
physical entity: Protein437
stoichiometric coefficient: 1.0

Stoichiometry522
type: Stoichiometry
physical entity: Protein433
stoichiometric coefficient: 1.0

Stoichiometry523
type: Stoichiometry
physical entity: Protein434
stoichiometric coefficient: 1.0

Stoichiometry528
type: Stoichiometry
physical entity: Protein442
stoichiometric coefficient: 1.0

Stoichiometry529
type: Stoichiometry
physical entity: Protein443
stoichiometric coefficient: 1.0

Stoichiometry526
type: Stoichiometry
physical entity: Protein438
stoichiometric coefficient: 1.0

Stoichiometry527
type: Stoichiometry
physical entity: Protein441
stoichiometric coefficient: 1.0

UniProt:PFE1345c
type: ProteinReference
xref: UnificationXref3755
organism: http://identifiers.org/taxonomy/5833

UnificationXref4351
type: UnificationXref
id: 5594851
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594851

UnificationXref4350
type: UnificationXref
id: REACT_233136
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_233136.1

UnificationXref4352
type: UnificationXref
id: 5594852
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594852

UnificationXref4353
type: UnificationXref
id: 5594853
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594853

UnificationXref4354
type: UnificationXref
id: REACT_231900
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_231900.1

UnificationXref4355
type: UnificationXref
id: 5594855
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594855

UnificationXref5800
type: UnificationXref
id: PF08_0071
db: UniProt

UnificationXref4356
type: UnificationXref
id: REACT_256152
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_256152.1

UnificationXref4357
type: UnificationXref
id: 5596932
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596932

UnificationXref4358
type: UnificationXref
id: REACT_233060
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_233060.1

UnificationXref4359
type: UnificationXref
id: 5596933
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596933

UnificationXref5804
type: UnificationXref
id: 5596489
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596489

UnificationXref5803
type: UnificationXref
id: 5596488
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596488

UnificationXref5802
type: UnificationXref
id: 5596487
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596487

UnificationXref5801
type: UnificationXref
id: 5596486
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596486

UnificationXref5808
type: UnificationXref
id: REACT_117738
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_117738.1

UnificationXref5807
type: UnificationXref
id: 1655882
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1655882

http://identifiers.org/pubmed/17331073
type: PublicationXref
id: 17331073
author: Wei, Y
author: Hornemann, T
author: von Eckardstein, A
db: Pubmed
title: Is the mammalian serine palmitoyltransferase a high-molecular-mass complex?
source: Biochem J 405:157-64
year: 2007

UnificationXref5806
type: UnificationXref
id: REACT_233459
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_233459.1

UnificationXref5805
type: UnificationXref
id: 5596491
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596491

PublicationXref1002
type: PublicationXref
id: 0079130356
author: Shih, VE
author: Chuang, DT
db: ISBN
title: Maple syrup urine disease (branched-chain ketoaciduria)
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 1971-2005
year: 2001

UnificationXref5809
type: UnificationXref
id: 1655887
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1655887

PublicationXref1008
type: PublicationXref
id: 0079130356
author: Williams, JC
author: Sweetman, L
db: ISBN
title: Branched chain organic acidurias
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 2125-2163
year: 2001

PublicationXref1009
type: PublicationXref
id: 0079130356
author: Cox, RP
db: ISBN
title: Errors of lysine metabolism
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 1965-1970
year: 2001

Stoichiometry510
type: Stoichiometry
physical entity: Protein421
stoichiometric coefficient: 1.0

Stoichiometry511
type: Stoichiometry
physical entity: Protein422
stoichiometric coefficient: 1.0

Stoichiometry512
type: Stoichiometry
physical entity: Protein423
stoichiometric coefficient: 1.0

Stoichiometry513
type: Stoichiometry
physical entity: Protein424
stoichiometric coefficient: 1.0

Stoichiometry514
type: Stoichiometry
physical entity: Protein425
stoichiometric coefficient: 1.0

UniProt:MAL8P1.81
type: ProteinReference
xref: UnificationXref1017
organism: http://identifiers.org/taxonomy/5833

Stoichiometry515
type: Stoichiometry
physical entity: Protein426
stoichiometric coefficient: 1.0

Stoichiometry516
type: Stoichiometry
physical entity: Protein427
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/7354072
type: PublicationXref
id: 7354072
author: Bodlaender, P
author: Shemin, D
author: Bevan, DR
db: Pubmed
title: Mechanism of porphobilinogen synthase. Requirement of Zn2+ for enzyme activity.
source: J Biol Chem 255:2030-5
year: 1980

Stoichiometry517
type: Stoichiometry
physical entity: Protein428
stoichiometric coefficient: 1.0

Stoichiometry518
type: Stoichiometry
physical entity: Protein429
stoichiometric coefficient: 1.0

UnificationXref4362
type: UnificationXref
id: REACT_253456
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253456.1

Stoichiometry519
type: Stoichiometry
physical entity: Protein430
stoichiometric coefficient: 1.0

UnificationXref4361
type: UnificationXref
id: 5597092
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597092

UnificationXref4360
type: UnificationXref
id: REACT_231788
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_231788.1

UnificationXref4365
type: UnificationXref
id: 5597094
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597094

UnificationXref4366
type: UnificationXref
id: REACT_238435
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_238435.1

UnificationXref4363
type: UnificationXref
id: 5597093
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597093

UnificationXref4364
type: UnificationXref
id: REACT_237474
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_237474.1

UnificationXref4369
type: UnificationXref
id: 5596918
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596918

UnificationXref5811
type: UnificationXref
id: 5596496
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596496

UnificationXref4367
type: UnificationXref
id: 5596759
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596759

UniProt:MAL8P1.83
type: ProteinReference
xref: UnificationXref3523
organism: http://identifiers.org/taxonomy/5833

UnificationXref5810
type: UnificationXref
id: REACT_117659
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_117659.1

UnificationXref4368
type: UnificationXref
id: REACT_241483
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_241483.1

UnificationXref5813
type: UnificationXref
id: 5596498
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596498

UnificationXref5812
type: UnificationXref
id: 5596497
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596497

UnificationXref5815
type: UnificationXref
id: REACT_220419
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_220419.2

PublicationXref1012
type: PublicationXref
id: 0079130356
author: Goodman, SI
author: Frerman, FE
db: ISBN
title: Organic acidemias due to defects in lysine oxidation: 2-ketoadipic acidemia and glutaric acidemia
source: The Metabolic and Molecular Bases of Inherited Disease, 8th ed (Book): 2195-2204
year: 2001

UnificationXref5814
type: UnificationXref
id: 5596500
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596500

UnificationXref5817
type: UnificationXref
id: REACT_173244
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_173244.2

http://identifiers.org/pubmed/16183910
type: PublicationXref
id: 16183910
author: Wettschureck, N
author: Offermanns, S
db: Pubmed
title: Mammalian G proteins and their cell type specific functions
source: Physiol Rev 85:1159-204
year: 2005

UnificationXref5816
type: UnificationXref
id: 3341308
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=3341308

UnificationXref5819
type: UnificationXref
id: 3341371
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=3341371

UnificationXref5818
type: UnificationXref
id: CHEBI:38574
db: ChEBI

Stoichiometry502
type: Stoichiometry
physical entity: Protein414
stoichiometric coefficient: 1.0

Stoichiometry503
type: Stoichiometry
physical entity: Protein415
stoichiometric coefficient: 1.0

Stoichiometry500
type: Stoichiometry
physical entity: Protein412
stoichiometric coefficient: 1.0

Stoichiometry501
type: Stoichiometry
physical entity: Protein413
stoichiometric coefficient: 1.0

UnificationXref4371
type: UnificationXref
id: 5596760
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596760

UnificationXref4370
type: UnificationXref
id: REACT_263427
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_263427.1

UnificationXref4373
type: UnificationXref
id: 983123
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=983123

Stoichiometry508
type: Stoichiometry
physical entity: Protein420
stoichiometric coefficient: 1.0

UnificationXref4372
type: UnificationXref
id: REACT_253420
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253420.1

Stoichiometry509
type: Stoichiometry
physical entity: PhysicalEntity2
stoichiometric coefficient: 7.0

Stoichiometry506
type: Stoichiometry
physical entity: Protein419
stoichiometric coefficient: 1.0

Stoichiometry507
type: Stoichiometry
physical entity: Protein418
stoichiometric coefficient: 1.0

Stoichiometry504
type: Stoichiometry
physical entity: Protein416
stoichiometric coefficient: 1.0

Stoichiometry505
type: Stoichiometry
physical entity: Protein417
stoichiometric coefficient: 1.0

UnificationXref5822
type: UnificationXref
id: 5594437
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594437

UnificationXref4378
type: UnificationXref
id: REACT_76778
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_76778.1

UnificationXref5821
type: UnificationXref
id: 5594435
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594435

UnificationXref4379
type: UnificationXref
id: CHEBI:15971
db: ChEBI

UnificationXref5820
type: UnificationXref
id: REACT_164233
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_164233.1

UnificationXref4374
type: UnificationXref
id: REACT_75986
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_75986.2

UnificationXref4375
type: UnificationXref
id: 983032
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=983032

UnificationXref4376
type: UnificationXref
id: REACT_76829
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_76829.1

UnificationXref4377
type: UnificationXref
id: 983036
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=983036

UnificationXref5829
type: UnificationXref
id: 29408
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29408

UnificationXref5828
type: UnificationXref
id: REACT_212645
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_212645.2

UnificationXref5827
type: UnificationXref
id: 5596505
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596505

UnificationXref5826
type: UnificationXref
id: 5594436
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594436

UnificationXref5825
type: UnificationXref
id: REACT_165067
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_165067.1

UnificationXref5824
type: UnificationXref
id: 3341317
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=3341317

http://identifiers.org/pubmed/12515382
type: PublicationXref
id: 12515382
author: Arndt-Jovin, DJ
author: Ingelfinger, D
author: Achsel, T
author: Lührmann, R
db: Pubmed
title: The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci
source: RNA 8:1489-501
year: 2002

UnificationXref5823
type: UnificationXref
id: CHEBI:38573
db: ChEBI

UnificationXref4384
type: UnificationXref
id: REACT_3974
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3974.2

UnificationXref4383
type: UnificationXref
id: 30102
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=30102

UnificationXref4382
type: UnificationXref
id: CHEBI:17191
db: ChEBI

UnificationXref4381
type: UnificationXref
id: REACT_3169
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3169.2

UnificationXref4380
type: UnificationXref
id: 29612
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29612

UnificationXref5831
type: UnificationXref
id: PF14_0368
db: UniProt

UnificationXref5830
type: UnificationXref
id: REACT_3714
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3714.1

UnificationXref5833
type: UnificationXref
id: PFL0725w
db: UniProt

UnificationXref4389
type: UnificationXref
id: 351979
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=351979

UnificationXref5832
type: UnificationXref
id: 5596507
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596507

UnificationXref4387
type: UnificationXref
id: REACT_3962
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3962.2

http://identifiers.org/pubmed/11044454
type: PublicationXref
id: 11044454
author: Wang, J
author: Jackowski, S
author: Lykidis, A
author: Karim, MA
db: Pubmed
title: Overexpression of a mammalian ethanolamine-specific kinase accelerates the CDP-ethanolamine pathway
source: J Biol Chem 276:2174-9
year: 2001

UnificationXref4388
type: UnificationXref
id: CHEBI:18019
db: ChEBI

UnificationXref4385
type: UnificationXref
id: CHEBI:15603
db: ChEBI

UnificationXref4386
type: UnificationXref
id: 29588
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29588

UnificationXref5839
type: UnificationXref
id: 5596514
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596514

UnificationXref5838
type: UnificationXref
id: 5596513
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596513

UnificationXref5835
type: UnificationXref
id: 5596510
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596510

UnificationXref5834
type: UnificationXref
id: 5596509
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596509

UnificationXref5837
type: UnificationXref
id: 5596512
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596512

UnificationXref5836
type: UnificationXref
id: 5596511
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596511

http://identifiers.org/pubmed/20051984
type: PublicationXref
id: 20051984
author: Schimenti, JC
author: Handel, MA
db: Pubmed
title: Genetics of mammalian meiosis: regulation, dynamics and impact on fertility
source: Nat Rev Genet 11:124-36
year: 2010

http://identifiers.org/pubmed/14508490
type: PublicationXref
id: 14508490
author: Sacks, D
author: Goyette, G
author: Desjardins, M
author: Princiotta, MF
author: Brunet, S
author: Bertholet, S
author: Houde, M
author: Laplante, A
author: Thibault, P
author: Gagnon, E
db: Pubmed
title: Phagosomes are competent organelles for antigen cross-presentation
source: Nature 425:402-6
year: 2003

UniProt:PFL0460w
type: ProteinReference
xref: UnificationXref3949
organism: http://identifiers.org/taxonomy/5833

UnificationXref5847
type: UnificationXref
id: 1222481
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1222481

UnificationXref4317
type: UnificationXref
id: 5596617
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596617

UnificationXref3704
type: UnificationXref
id: PF10_0298
db: UniProt

UnificationXref5848
type: UnificationXref
id: REACT_111700
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_111700.1

UnificationXref4316
type: UnificationXref
id: 5596616
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596616

UnificationXref3705
type: UnificationXref
id: 5593230
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593230

UnificationXref5845
type: UnificationXref
id: REACT_262362
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_262362.1

UnificationXref4319
type: UnificationXref
id: 5358610
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5358610

UnificationXref3706
type: UnificationXref
id: 5593250
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593250

UnificationXref5846
type: UnificationXref
id: CHEBI:25941
db: ChEBI

UnificationXref4318
type: UnificationXref
id: REACT_257630
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_257630.1

UnificationXref3707
type: UnificationXref
id: 5593193
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593193

UniProt:MAL8P1.58
type: ProteinReference
xref: UnificationXref1782
organism: http://identifiers.org/taxonomy/5833

UnificationXref3700
type: UnificationXref
id: PF14_0025
db: UniProt

UnificationXref3701
type: UnificationXref
id: 5593226
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593226

UnificationXref5849
type: UnificationXref
id: CHEBI:16301
db: ChEBI

UnificationXref3702
type: UnificationXref
id: PF14_0632
db: UniProt

UnificationXref3703
type: UnificationXref
id: 5593224
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593224

UnificationXref5840
type: UnificationXref
id: 5596515
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596515

UnificationXref4311
type: UnificationXref
id: 5596605
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596605

UnificationXref4310
type: UnificationXref
id: REACT_228484
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_228484.1

UnificationXref5843
type: UnificationXref
id: 5596518
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596518

UnificationXref4313
type: UnificationXref
id: REACT_253798
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253798.1

UnificationXref5844
type: UnificationXref
id: 5596520
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596520

UnificationXref4312
type: UnificationXref
id: 5596607
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596607

UnificationXref5841
type: UnificationXref
id: MAL7P1.159
db: UniProt

UnificationXref4315
type: UnificationXref
id: 5596612
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596612

UnificationXref5842
type: UnificationXref
id: 5596517
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596517

UnificationXref4314
type: UnificationXref
id: PF07_0105
db: UniProt

http://identifiers.org/pubmed/14508489
type: PublicationXref
id: 14508489
author: Kleijmeer, M
author: Saveanu, L
author: Amigorena, S
author: Van Endert, P
author: Davoust, J
author: Guermonprez, P
db: Pubmed
title: ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells
source: Nature 425:397-402
year: 2003

UnificationXref3709
type: UnificationXref
id: 5593191
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593191

UnificationXref3708
type: UnificationXref
id: MAL8P1.128
db: UniProt

UnificationXref5856
type: UnificationXref
id: 5596705
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596705

UnificationXref3717
type: UnificationXref
id: 5593179
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593179

UnificationXref5857
type: UnificationXref
id: REACT_191641
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_191641.3

UnificationXref4329
type: UnificationXref
id: 5358527
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5358527

UnificationXref3718
type: UnificationXref
id: PFD0665c
db: UniProt

UnificationXref5858
type: UnificationXref
id: PFF0330w
db: UniProt

UnificationXref4328
type: UnificationXref
id: REACT_241593
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_241593.1

UnificationXref3715
type: UnificationXref
id: 5593199
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593199

UnificationXref5859
type: UnificationXref
id: 5594775
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594775

UnificationXref4327
type: UnificationXref
id: 5597118
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597118

UnificationXref3716
type: UnificationXref
id: MAL13P1.343
db: UniProt

UnificationXref3713
type: UnificationXref
id: 5593195
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593195

UniProt:MAL8P1.48
type: ProteinReference
xref: UnificationXref5384
organism: http://identifiers.org/taxonomy/5833

UnificationXref3714
type: UnificationXref
id: PF14_0676
db: UniProt

UnificationXref3711
type: UnificationXref
id: 5593197
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593197

UnificationXref3712
type: UnificationXref
id: PFE0915c
db: UniProt

UnificationXref4322
type: UnificationXref
id: REACT_2517
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2517.2

UnificationXref4321
type: UnificationXref
id: 113541
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113541

UnificationXref3710
type: UnificationXref
id: PF13_0156
db: UniProt

UniProt:MAL8P1.43
type: ProteinReference
xref: UnificationXref5418
organism: http://identifiers.org/taxonomy/5833

UnificationXref5850
type: UnificationXref
id: 1222379
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1222379

UnificationXref4320
type: UnificationXref
id: REACT_228610
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_228610.1

UnificationXref5851
type: UnificationXref
id: REACT_125495
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_125495.1

UnificationXref5852
type: UnificationXref
id: 5596522
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596522

UnificationXref4326
type: UnificationXref
id: REACT_231819
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_231819.1

UnificationXref5853
type: UnificationXref
id: REACT_255610
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_255610.1

UnificationXref4325
type: UnificationXref
id: 5596615
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596615

http://identifiers.org/pubmed/15758951
type: PublicationXref
id: 15758951
author: Wang, GX
author: Poo, MM
db: Pubmed
title: Requirement of TRPC channels in netrin-1-induced chemotropic turning of nerve growth cones
source: Nature 434:898-904
year: 2005

UnificationXref5854
type: UnificationXref
id: 5596704
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596704

UnificationXref4324
type: UnificationXref
id: REACT_2883
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2883.1

UnificationXref5855
type: UnificationXref
id: REACT_191640
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_191640.3

UnificationXref4323
type: UnificationXref
id: 164121
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=164121

UnificationXref3719
type: UnificationXref
id: 5593218
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593218

Epidermal Growth Factor Receptor (EGFR) signaling
type: Pathway
data source: Provenance1
pathway component: REACT 241299.1
pathway component: GAB1 signalosome
pathway component: REACT 261823.1
pathway component: REACT 242135.1
evidence: Evidence80
xref: UnificationXref517
xref: UnificationXref516
xref: RelationshipXref68
pathway order: PathwayStep72
pathway order: PathwayStep71
pathway order: PathwayStep67
pathway order: PathwayStep78
display name: Signaling by EGFR
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref3722
type: UnificationXref
id: PF13_0063
db: UniProt

Defective MMAB causes methylmalonic aciduria type cblB
type: Pathway
data source: Provenance1
pathway component: REACT 242840.1
evidence: Evidence200
xref: UnificationXref1158
xref: UnificationXref1157
pathway order: PathwayStep189
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref3723
type: UnificationXref
id: 5593214
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593214

UnificationXref3724
type: UnificationXref
id: MAL13P1.190
db: UniProt

UnificationXref3725
type: UnificationXref
id: 5593234
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593234

UnificationXref5869
type: UnificationXref
id: 5594779
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594779

UnificationXref4339
type: UnificationXref
id: 5596614
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596614

UnificationXref3726
type: UnificationXref
id: PF11_0314
db: UniProt

mRNA Splicing - Minor Pathway
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction460
pathway component: BiochemicalReaction459
pathway component: BiochemicalReaction458
evidence: Evidence948
xref: UnificationXref5453
xref: UnificationXref5452
xref: RelationshipXref687
pathway order: PathwayStep924
pathway order: PathwayStep926
pathway order: PathwayStep925
display name: U12 Dependent Splicing
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4338
type: UnificationXref
id: 5596613
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596613

UnificationXref3727
type: UnificationXref
id: 5593216
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593216

UnificationXref5867
type: UnificationXref
id: 5594781
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594781

UnificationXref3728
type: UnificationXref
id: PF08_0109
db: UniProt

UnificationXref5868
type: UnificationXref
id: PFI0290c
db: UniProt

UnificationXref3729
type: UnificationXref
id: 5593236
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593236

UniProt:MAL8P1.72
type: ProteinReference
xref: UnificationXref3181
organism: http://identifiers.org/taxonomy/5833

UnificationXref5865
type: UnificationXref
id: 5594783
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594783

UnificationXref4335
type: UnificationXref
id: 5596602
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596602

UnificationXref5866
type: UnificationXref
id: PF11_0359
db: UniProt

UnificationXref4334
type: UnificationXref
id: REACT_228934
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_228934.1

UnificationXref5863
type: UnificationXref
id: 5594785
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594785

UnificationXref4337
type: UnificationXref
id: REACT_230002
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_230002.1

UnificationXref5864
type: UnificationXref
id: PF11_0463
db: UniProt

UnificationXref4336
type: UnificationXref
id: 5596604
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596604

UnificationXref5861
type: UnificationXref
id: 5594777
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594777

UnificationXref4331
type: UnificationXref
id: 5596600
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596600

UnificationXref5862
type: UnificationXref
id: PFD0745c
db: UniProt

UnificationXref4330
type: UnificationXref
id: REACT_229232
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_229232.1

UnificationXref4333
type: UnificationXref
id: 5358521
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5358521

UnificationXref3720
type: UnificationXref
id: PFB0260w
db: UniProt

UnificationXref5860
type: UnificationXref
id: PF14_0277
db: UniProt

UnificationXref4332
type: UnificationXref
id: 5596601
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596601

UnificationXref3721
type: UnificationXref
id: 5593232
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593232

UnificationXref4340
type: UnificationXref
id: REACT_247045
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_247045.1

UnificationXref3735
type: UnificationXref
id: 5593251
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593251

UnificationXref3736
type: UnificationXref
id: 5593253
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593253

UniProt:MAL8P1.69
type: ProteinReference
xref: UnificationXref470
organism: http://identifiers.org/taxonomy/5833

UnificationXref3733
type: UnificationXref
id: PF10_0081
db: UniProt

UnificationXref3734
type: UnificationXref
id: 5593212
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593212

UnificationXref5878
type: UnificationXref
id: 5594805
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594805

UnificationXref3739
type: UnificationXref
id: REACT_236500
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_236500.1

UnificationXref5879
type: UnificationXref
id: 5594806
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594806

UnificationXref3737
type: UnificationXref
id: REACT_227918
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_227918.2

UnificationXref4349
type: UnificationXref
id: 5596758
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596758

UnificationXref3738
type: UnificationXref
id: 5596665
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596665

http://identifiers.org/pubmed/16873062
type: PublicationXref
id: 16873062
author: Kadyrov, Farid A
author: Modrich, Paul
author: Dzantiev, Leonid
author: Constantin, Nicoleta
db: Pubmed
title: Endonucleolytic function of MutLalpha in human mismatch repair
source: Cell 126:297-308
year: 2006

UnificationXref5874
type: UnificationXref
id: REACT_211290
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_211290.2

UnificationXref4348
type: UnificationXref
id: REACT_261032
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_261032.1

UnificationXref5875
type: UnificationXref
id: 5594794
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594794

UnificationXref4347
type: UnificationXref
id: 5596757
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596757

http://identifiers.org/pubmed/17307970
type: PublicationXref
id: 17307970
author: Omori, K
author: Kotera, J
db: Pubmed
title: Overview of PDEs and their regulation
source: Circ Res 100:309-27
year: 2007

UnificationXref5876
type: UnificationXref
id: 5594804
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594804

UnificationXref4346
type: UnificationXref
id: REACT_244513
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_244513.1

UnificationXref5877
type: UnificationXref
id: REACT_256190
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_256190.1

UnificationXref4345
type: UnificationXref
id: 5596772
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596772

UnificationXref5870
type: UnificationXref
id: 5594786
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594786

UnificationXref4344
type: UnificationXref
id: REACT_236245
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_236245.1

UnificationXref3731
type: UnificationXref
id: PF11_0303
db: UniProt

UnificationXref5871
type: UnificationXref
id: 5594773
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594773

UnificationXref4343
type: UnificationXref
id: 5597119
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597119

UnificationXref3732
type: UnificationXref
id: 5593238
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593238

UnificationXref5872
type: UnificationXref
id: 5594787
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594787

UnificationXref4342
type: UnificationXref
id: REACT_255527
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_255527.1

UnificationXref5873
type: UnificationXref
id: 5594788
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594788

UnificationXref4341
type: UnificationXref
id: 5597120
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597120

UnificationXref3730
type: UnificationXref
id: 5593210
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593210

http://identifiers.org/pubmed/9045610
type: PublicationXref
id: 9045610
author: Weaver, PL
author: Chuang, RY
author: Chang, TH
author: Liu, Z
db: Pubmed
title: Requirement of the DEAD-Box protein ded1p for messenger RNA translation.
source: Science 275:1468-71
year: 1997

http://identifiers.org/pubmed/16510870
type: PublicationXref
id: 16510870
author: Hannon, GJ
author: Parker, R
author: Liu, J
author: Valencia-Sanchez, MA
db: Pubmed
title: Control of translation and mRNA degradation by miRNAs and siRNAs
source: Genes Dev 20:515-24
year: 2006

SequenceSite112
type: SequenceSite
position status: EQUAL
sequence position: 830

UnificationXref2282
type: UnificationXref
id: 5595538
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595538

SequenceSite113
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2283
type: UnificationXref
id: 5595540
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595540

SequenceSite110
type: SequenceSite
position status: EQUAL
sequence position: 205

UnificationXref2280
type: UnificationXref
id: 113527
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113527

SequenceSite111
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2281
type: UnificationXref
id: REACT_4600
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4600.2

UnificationXref3333
type: UnificationXref
id: 5595840
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595840

SequenceSite109
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref3334
type: UnificationXref
id: 5595841
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595841

SequenceSite108
type: SequenceSite
position status: EQUAL
sequence position: 1177

UnificationXref2289
type: UnificationXref
id: REACT_181058
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_181058.3

UnificationXref3335
type: UnificationXref
id: 5595843
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595843

SequenceSite107
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2288
type: UnificationXref
id: 5595535
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595535

UnificationXref3336
type: UnificationXref
id: REACT_234478
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_234478.1

SequenceSite106
type: SequenceSite
position status: EQUAL
sequence position: 1132

UnificationXref2287
type: UnificationXref
id: 5595533
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595533

PublicationXref1271
type: PublicationXref
author: Machin, S
author: Allford, S
title: Haemostasis
source: Surgery (Oxford) 22:200a - 200d
year: 2004

SequenceSite105
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2286
type: UnificationXref
id: 5595532
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595532

UnificationXref3330
type: UnificationXref
id: 5595849
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595849

PublicationXref1272
type: PublicationXref
author: Marder, V
author: George, J
author: Colman, R
author: Goldhaber, S
author: Clowes, A
title: Hemostasis and Thrombosis: Basic Principles and Clinical Practice
year: 2005

SequenceSite104
type: SequenceSite
position status: EQUAL
sequence position: 1164

UnificationXref2285
type: UnificationXref
id: PF14_0508
db: UniProt

UnificationXref3331
type: UnificationXref
id: REACT_219166
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_219166.2

SequenceSite103
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2284
type: UnificationXref
id: REACT_212575
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_212575.2

UnificationXref3332
type: UnificationXref
id: 5594644
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594644

UnificationXref3337
type: UnificationXref
id: 5595842
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595842

UnificationXref3338
type: UnificationXref
id: REACT_253249
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253249.1

UnificationXref3339
type: UnificationXref
id: 5597047
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597047

PublicationXref1259
type: PublicationXref
author: Greene, E
author: Henikoff, S
title: Kinesin home page
url: http://www.cellbio.duke.edu/kinesin/

SequenceSite100
type: SequenceSite
position status: EQUAL
sequence position: 919

UnificationXref2270
type: UnificationXref
id: REACT_246052
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_246052.1

SequenceSite101
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2271
type: UnificationXref
id: CHEBI:151
db: ChEBI

SequenceSite102
type: SequenceSite
position status: EQUAL
sequence position: 946

UnificationXref2272
type: UnificationXref
id: 29938
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29938

UnificationXref2278
type: UnificationXref
id: PF13_0242
db: UniProt

UnificationXref3324
type: UnificationXref
id: 5595839
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595839

UnificationXref2277
type: UnificationXref
id: REACT_5633
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5633.1

UnificationXref3325
type: UnificationXref
id: 5595845
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595845

UnificationXref3322
type: UnificationXref
id: PFC0860w
db: UniProt

UnificationXref2279
type: UnificationXref
id: 5595537
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595537

UnificationXref3323
type: UnificationXref
id: 5595838
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595838

UnificationXref2274
type: UnificationXref
id: 113563
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113563

UnificationXref3320
type: UnificationXref
id: 5595844
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595844

UnificationXref2273
type: UnificationXref
id: REACT_5798
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5798.3

UnificationXref3321
type: UnificationXref
id: REACT_246888
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_246888.1

UnificationXref2276
type: UnificationXref
id: 113600
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113600

UnificationXref2275
type: UnificationXref
id: REACT_5783
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5783.1

http://identifiers.org/pubmed/17035995
type: PublicationXref
id: 17035995
author: De Camilli, Pietro
author: Di Paolo, G
db: Pubmed
title: Phosphoinositides in cell regulation and membrane dynamics
source: Nature 443:651-7
year: 2006

UnificationXref3328
type: UnificationXref
id: 5595847
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595847

UnificationXref3329
type: UnificationXref
id: 5595848
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595848

UnificationXref3326
type: UnificationXref
id: REACT_209640
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_209640.2

UnificationXref3327
type: UnificationXref
id: PFL2190c
db: UniProt

http://identifiers.org/pubmed/15845384
type: PublicationXref
id: 15845384
author: Ohira, RH
author: Dipple, KM
author: McCabe, ER
author: Zhang, YH
db: Pubmed
title: Human and murine glycerol kinase: influence of exon 18 alternative splicing on function
source: Biochem Biophys Res Commun 331:239-46
year: 2005

http://identifiers.org/pubmed/10899997
type: PublicationXref
id: 10899997
author: Bobik, E
author: Das, T
author: Mukerji, P
author: Thurmond, JM
author: Parker-Barnes, JM
author: Chaung, LT
author: Leonard, AE
author: Huang, YS
db: Pubmed
title: Identification and characterization of an enzyme involved in the elongation of n-6 and n-3 polyunsaturated fatty acids
source: Proc Natl Acad Sci U S A 97:8284-9
year: 2000

UnificationXref2260
type: UnificationXref
id: 5593546
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593546

UnificationXref2261
type: UnificationXref
id: REACT_256087
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_256087.1

UnificationXref2265
type: UnificationXref
id: REACT_4667
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4667.2

UnificationXref2264
type: UnificationXref
id: 29654
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29654

UnificationXref2263
type: UnificationXref
id: REACT_30108
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_30108.5

UnificationXref2262
type: UnificationXref
id: 5596691
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596691

UnificationXref3310
type: UnificationXref
id: PFE1420w
db: UniProt

UnificationXref2269
type: UnificationXref
id: 5593488
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593488

UnificationXref3311
type: UnificationXref
id: 5595717
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595717

UnificationXref2268
type: UnificationXref
id: 5593486
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593486

UnificationXref3312
type: UnificationXref
id: PFE0880c
db: UniProt

UnificationXref2267
type: UnificationXref
id: 5593485
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593485

UnificationXref3313
type: UnificationXref
id: 5595719
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595719

http://identifiers.org/pubmed/18388293
type: PublicationXref
id: 18388293
author: Kumar, R
author: An, S
author: Benkovic, SJ
author: Sheets, ED
db: Pubmed
title: Reversible compartmentalization of de novo purine biosynthetic complexes in living cells
source: Science 320:103-6
year: 2008

UnificationXref2266
type: UnificationXref
id: PF10_0218
db: UniProt

UnificationXref3314
type: UnificationXref
id: 5595720
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595720

UnificationXref3315
type: UnificationXref
id: 5595721
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595721

UnificationXref3316
type: UnificationXref
id: REACT_213614
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_213614.2

UnificationXref3317
type: UnificationXref
id: PFC0770c
db: UniProt

UnificationXref3318
type: UnificationXref
id: 5595835
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595835

UnificationXref3319
type: UnificationXref
id: 5595836
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595836

http://identifiers.org/pubmed/2040271
type: PublicationXref
id: 2040271
author: Sadahiro, S
author: Matsuda, T
author: Takenaka, M
author: Tanaka, T
author: Noguchi, T
author: Hirai, H
author: Imai, E
author: Yamada, K
db: Pubmed
title: Isolation and characterization of the human pyruvate kinase M gene
source: Eur J Biochem 198:101-6
year: 1991

5,10-methylenetetrahydrofolate polyglutamate
type: SmallMoleculeReference
name: 5,10-methylenetetrahydrofolate polyglutamate macromolecule
name: 5,10-methylenetetrahydrofolate polyglutamate macromolecule [ChEBI:60473]
xref: UnificationXref1106

http://identifiers.org/pubmed/16839620
type: PublicationXref
id: 16839620
author: Kushner, JP
author: Phillips, JD
author: Ajioka, RS
db: Pubmed
title: Biosynthesis of heme in mammals
source: Biochim Biophys Acta 1763:723-36
year: 2006

http://identifiers.org/pubmed/21106529
type: PublicationXref
id: 21106529
author: Oakley, Aaron J
author: Casarotto, Marco G
author: Brock, Joseph
author: Board, PG
author: Zhou, Huina
db: Pubmed
title: Novel folding and stability defects cause a deficiency of human glutathione transferase omega 1
source: J. Biol. Chem. 286:4271-9
year: 2011

UnificationXref2250
type: UnificationXref
id: PF10_0407
db: UniProt

UnificationXref2252
type: UnificationXref
id: PFL1550w
db: UniProt

UnificationXref2251
type: UnificationXref
id: 5593543
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593543

UnificationXref2254
type: UnificationXref
id: 5593464
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593464

UnificationXref2253
type: UnificationXref
id: 5593463
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593463

UnificationXref2256
type: UnificationXref
id: MOD:00127
db: MOD

UnificationXref3302
type: UnificationXref
id: 5594989
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594989

UnificationXref2255
type: UnificationXref
id: 5593465
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593465

UnificationXref3303
type: UnificationXref
id: REACT_231583
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_231583.1

UnificationXref2258
type: UnificationXref
id: 5593542
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593542

UnificationXref3300
type: UnificationXref
id: 5594987
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594987

UnificationXref2257
type: UnificationXref
id: 5593541
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593541

UnificationXref3301
type: UnificationXref
id: 5594988
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594988

Platelet activation, signaling and aggregation
type: Pathway
data source: Provenance1
pathway component: REACT 244972.1
pathway component: Response to elevated platelet cytosolic Ca2+
pathway component: REACT 239738.1
pathway component: REACT 240387.1
evidence: Evidence535
xref: RelationshipXref519
xref: UnificationXref3308
xref: UnificationXref3309
pathway order: PathwayStep526
pathway order: PathwayStep520
pathway order: PathwayStep518
pathway order: PathwayStep517
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref3306
type: UnificationXref
id: 5596955
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596955

UnificationXref2259
type: UnificationXref
id: 5593544
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593544

UnificationXref3307
type: UnificationXref
id: REACT_234828
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_234828.1

UnificationXref3304
type: UnificationXref
id: 5596954
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596954

UnificationXref3305
type: UnificationXref
id: REACT_243308
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_243308.1

UnificationXref3308
type: UnificationXref
id: 5596850
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596850

UnificationXref3309
type: UnificationXref
id: REACT_259616
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_259616.1

http://identifiers.org/pubmed/3356695
type: PublicationXref
id: 3356695
author: Panniers, R
author: Rowlands, AG
author: Henshaw, EC
db: Pubmed
title: The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2.
source: J Biol Chem 263:5526-33
year: 1988

http://identifiers.org/pubmed/18583706
type: PublicationXref
id: 18583706
author: Bakovic, M
author: Zhu, L
author: Johnson, C
db: Pubmed
title: Stimulation of the human CTP:phosphoethanolamine cytidylyltransferase gene by early growth response protein 1
source: J Lipid Res 49:2197-211
year: 2008

Oxoglutaric acid
type: SmallMoleculeReference
name: 2-Oxoglutarate [ChEBI:30915]
name: 2-Oxoglutarate
name: alpha-Ketoglutaric acid
name: 2-Ketoglutaric acid
xref: UnificationXref767

http://identifiers.org/pubmed/1607388
type: PublicationXref
id: 1607388
author: Bernstein, HD
author: Sparks, L
author: Niclas, J
author: Navone, F
author: Vale, RD
author: McCaffrey, G
author: Hom-Booher, N
db: Pubmed
title: Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells
source: J Cell Biol 117:1263-75
year: 1992

http://identifiers.org/pubmed/12323090
type: PublicationXref
id: 12323090
author: Burdge, GC
author: Wootton, SA
db: Pubmed
title: Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women
source: Br J Nutr 88:411-20
year: 2002

http://identifiers.org/pubmed/2069720
type: PublicationXref
id: 2069720
author: Myöhänen, S
author: Kauppinen, L
author: Jänne, J
author: Wahlfors, J
author: Alhonen, L
db: Pubmed
title: Human spermidine synthase gene: structure and chromosomal localization
source: DNA Cell Biol 10:467-74
year: 1991

http://identifiers.org/pubmed/12323085
type: PublicationXref
id: 12323085
author: Burdge, GC
author: Wootton, SA
author: Jones, AE
db: Pubmed
title: Eicosapentaenoic and docosapentaenoic acids are the principal products of alpha-linolenic acid metabolism in young men*
source: Br J Nutr 88:355-63
year: 2002

Depyrimidination
type: Pathway
data source: Provenance1
pathway component: REACT 259424.1
pathway component: REACT 241125.1
evidence: Evidence672
xref: UnificationXref4171
xref: UnificationXref4172
xref: RelationshipXref568
pathway order: PathwayStep650
pathway order: PathwayStep655
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref2290
type: UnificationXref
id: CHEBI:15380
db: ChEBI

UnificationXref2292
type: UnificationXref
id: REACT_2852
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2852.2

UnificationXref2291
type: UnificationXref
id: 70958
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=70958

UnificationXref2294
type: UnificationXref
id: 5593497
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593497

Interleukin-2 signaling
type: Pathway
data source: Provenance1
pathway component: REACT 238671.1
evidence: Evidence760
xref: UnificationXref4555
xref: UnificationXref4556
pathway order: PathwayStep70
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref2293
type: UnificationXref
id: PF08_0045
db: UniProt

UniProt:PFF0715c
type: ProteinReference
xref: UnificationXref4131
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/14761955
type: PublicationXref
id: 14761955
author: Jacob, J
author: Chazin, WJ
author: Lee, YT
author: Nowotny, M
author: Kuznicki, J
author: Michowski, W
db: Pubmed
title: Human Sgt1 binds HSP90 through the CHORD-Sgt1 domain and not the tetratricopeptide repeat domain
source: J Biol Chem 279:16511-7
year: 2004

UnificationXref2295
type: UnificationXref
id: 5593498
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593498

UnificationXref2296
type: UnificationXref
id: 5593499
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593499

UnificationXref2297
type: UnificationXref
id: PF13_0121
db: UniProt

UnificationXref2298
type: UnificationXref
id: 5593502
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593502

UnificationXref2299
type: UnificationXref
id: CHEBI:17460
db: ChEBI

http://identifiers.org/pubmed/17545517
type: PublicationXref
id: 17545517
author: Baines, AJ
author: Russell, GA
author: Gullick, WJ
author: Boyle, MM
author: Smart, LV
author: Morgan, BJ
author: Frost, TM
author: Hayes, NV
author: Blackburn, E
db: Pubmed
title: Identification and characterization of novel spliced variants of neuregulin 4 in prostate cancer
source: Clin Cancer Res 13:3147-55
year: 2007

UnificationXref2201
type: UnificationXref
id: 5595934
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595934

UnificationXref2200
type: UnificationXref
id: 5595933
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595933

UnificationXref118
type: UnificationXref
id: REACT_232791
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_232791.1

UnificationXref2203
type: UnificationXref
id: 29502
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29502

UnificationXref119
type: UnificationXref
id: 5596982
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596982

UnificationXref2202
type: UnificationXref
id: CHEBI:17295
db: ChEBI

UnificationXref116
type: UnificationXref
id: 5595359
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595359

UnificationXref117
type: UnificationXref
id: 5595361
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595361

UnificationXref114
type: UnificationXref
id: 70106
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=70106

UnificationXref115
type: UnificationXref
id: REACT_4941
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4941.2

UnificationXref2209
type: UnificationXref
id: 5596929
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596929

UnificationXref2208
type: UnificationXref
id: REACT_192707
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192707.3

UnificationXref2205
type: UnificationXref
id: 5596047
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596047

UnificationXref2204
type: UnificationXref
id: REACT_4077
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4077.3

UnificationXref2207
type: UnificationXref
id: 5597054
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597054

UnificationXref2206
type: UnificationXref
id: REACT_263315
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_263315.1

VEGFR2 mediated cell proliferation
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction34
pathway component: BiochemicalReaction35
pathway component: REACT 238671.1
evidence: Evidence786
xref: UnificationXref4607
xref: UnificationXref4608
pathway order: PathwayStep70
pathway order: PathwayStep64
pathway order: PathwayStep63
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

Stoichiometry497
type: Stoichiometry
physical entity: Protein409
stoichiometric coefficient: 1.0

Stoichiometry496
type: Stoichiometry
physical entity: Protein408
stoichiometric coefficient: 1.0

Stoichiometry499
type: Stoichiometry
physical entity: Protein411
stoichiometric coefficient: 1.0

Stoichiometry498
type: Stoichiometry
physical entity: Protein410
stoichiometric coefficient: 1.0

UnificationXref124
type: UnificationXref
id: CHEBI:18248
db: ChEBI

UnificationXref123
type: UnificationXref
id: REACT_3201
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3201.3

UnificationXref122
type: UnificationXref
id: 29426
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29426

UnificationXref121
type: UnificationXref
id: CHEBI:29105
db: ChEBI

Synthesis of UDP-N-acetyl-glucosamine
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction436
pathway component: BiochemicalReaction437
pathway component: BiochemicalReaction435
evidence: Evidence882
xref: UnificationXref5107
xref: RelationshipXref661
xref: UnificationXref5108
pathway order: PathwayStep859
pathway order: PathwayStep860
pathway order: PathwayStep861
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref120
type: UnificationXref
id: REACT_239212
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_239212.1

SequenceSite1605
type: SequenceSite
position status: EQUAL
sequence position: 1063

UnificationXref107
type: UnificationXref
id: 429130
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=429130

SequenceSite1606
type: SequenceSite
position status: EQUAL
sequence position: 33

UnificationXref108
type: UnificationXref
id: REACT_20151
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_20151.2

SequenceSite1603
type: SequenceSite
position status: EQUAL
sequence position: 477

UnificationXref109
type: UnificationXref
id: CHEBI:15378
db: ChEBI

SequenceSite1604
type: SequenceSite
position status: EQUAL
sequence position: 27

SequenceSite1601
type: SequenceSite
position status: EQUAL
sequence position: 360

UnificationXref103
type: UnificationXref
id: REACT_253661
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253661.1

SequenceSite1602
type: SequenceSite
position status: EQUAL
sequence position: 17

UnificationXref104
type: UnificationXref
id: 5596980
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596980

UnificationXref105
type: UnificationXref
id: REACT_192344
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192344.3

SequenceSite1600
type: SequenceSite
position status: EQUAL
sequence position: 19

UnificationXref106
type: UnificationXref
id: CHEBI:17268
db: ChEBI

http://identifiers.org/pubmed/19416660
type: PublicationXref
id: 19416660
author: Ren, M
author: Xu, Y
author: Malhotra, A
author: Schlame, M
db: Pubmed
title: Formation of molecular species of mitochondrial cardiolipin. 1. A novel transacylation mechanism to shuttle fatty acids between sn-1 and sn-2 positions of multiple phospholipid species
source: Biochim Biophys Acta 1791:314-20
year: 2009

http://identifiers.org/pubmed/17597991
type: PublicationXref
id: 17597991
author: Ruggeri, ZM
db: Pubmed
title: Von Willebrand factor: looking back and looking forward
source: Thromb Haemost 98:55-62
year: 2007

UniProt:PFB0550w
type: ProteinReference
xref: UnificationXref4014
organism: http://identifiers.org/taxonomy/5833

UnificationXref111
type: UnificationXref
id: REACT_13894
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_13894.1

UnificationXref110
type: UnificationXref
id: 351626
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=351626

UnificationXref113
type: UnificationXref
id: REACT_20018
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_20018.2

UnificationXref112
type: UnificationXref
id: 426910
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=426910

UnificationXref3397
type: UnificationXref
id: PF14_0391
db: UniProt

UnificationXref3398
type: UnificationXref
id: 5593730
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593730

http://identifiers.org/pubmed/17531815
type: PublicationXref
id: 17531815
author: Beese, Lorena S
author: Iyer, Ravi R
author: Changela, Anita
author: Pohlhaus, Timothy J
author: Modrich, Paul L
author: Warren, Joshua J
db: Pubmed
title: Structure of the human MutSalpha DNA lesion recognition complex
source: Mol. Cell 26:579-92
year: 2007

UnificationXref3395
type: UnificationXref
id: PF08_0039
db: UniProt

UnificationXref3396
type: UnificationXref
id: 5593754
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593754

Generation of second messenger molecules
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction381
pathway component: BiochemicalReaction380
evidence: Evidence718
xref: UnificationXref4357
xref: UnificationXref4358
pathway order: PathwayStep699
pathway order: PathwayStep698
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref3399
type: UnificationXref
id: PF07_0079
db: UniProt

http://identifiers.org/pubmed/19487573
type: PublicationXref
id: 19487573
author: Agami, Reuven
author: Rouhanifard, Sara H
author: Holland, Eric C
author: Tuschl, Thomas
author: Huse, Jason T
author: Hambardzumyan, Dolores
author: Brennan, Cameron
author: Sohn-Lee, Cherin
author: le Sage, Carlos
author: Wee, Boyoung
author: Pena, John
db: Pubmed
title: The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo
source: Genes Dev. 23:1327-37
year: 2009

Cell Cycle
type: Pathway
data source: Provenance1
pathway component: REACT 249999.1
pathway component: REACT 235042.1
pathway component: REACT 202009.2
evidence: Evidence614
xref: UnificationXref3908
xref: UnificationXref3909
pathway order: PathwayStep600
pathway order: PathwayStep603
pathway order: PathwayStep589
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/14660560
type: PublicationXref
id: 14660560
author: Yu, Y
author: Arnold, E
author: Shen, N
author: Ding, Jianping
author: Xu, X
author: Jin, Y
author: Xu, F
author: Jia, J
author: Liu, Y
db: Pubmed
title: Crystal structure of human tryptophanyl-tRNA synthetase catalytic fragment: insights into substrate recognition, tRNA binding, and angiogenesis activity
source: J Biol Chem 279:8378-88
year: 2004

http://identifiers.org/pubmed/18511455
type: PublicationXref
id: 18511455
author: Giacomini, KM
author: Hurowitz, E
author: Zador, Z
author: Sorani, MD
author: Manley, GT
author: Yan, D
db: Pubmed
title: Novel variants in human Aquaporin-4 reduce cellular water permeability
source: Hum Mol Genet 17:2379-89
year: 2008

http://identifiers.org/pubmed/15381398
type: PublicationXref
id: 15381398
author: Jaffe, EK
db: Pubmed
title: The porphobilinogen synthase catalyzed reaction mechanism
source: Bioorg Chem 32:316-25
year: 2004

UnificationXref3390
type: UnificationXref
id: 5593808
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593808

http://identifiers.org/pubmed/14660569
type: PublicationXref
id: 14660569
author: Chaussade, C
author: Mandel, JL
author: Liaubet, L
author: Payrastre, B
author: Pendaries, C
author: Tronchère, H
author: Laporte, J
author: Pirola, L
db: Pubmed
title: Production of phosphatidylinositol 5-phosphate by the phosphoinositide 3-phosphatase myotubularin in mammalian cells
source: J Biol Chem 279:7304-12
year: 2004

UnificationXref102
type: UnificationXref
id: 5595358
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595358

UnificationXref3394
type: UnificationXref
id: 5593752
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593752

UnificationXref101
type: UnificationXref
id: 5595356
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595356

UnificationXref3393
type: UnificationXref
id: PF14_0240
db: UniProt

UnificationXref100
type: UnificationXref
id: 5595355
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595355

UnificationXref3392
type: UnificationXref
id: 5593779
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593779

UnificationXref3391
type: UnificationXref
id: PF07_0043
db: UniProt

http://identifiers.org/pubmed/7913615
type: PublicationXref
id: 7913615
author: Sheng, H
author: Warner, TD
author: Murad, F
author: Mitchell, JA
db: Pubmed
title: Effects of cyclic GMP on smooth muscle relaxation
source: Adv Pharmacol 26:171-94
year: 1994

UnificationXref3384
type: UnificationXref
id: 5593781
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593781

UnificationXref3385
type: UnificationXref
id: PF14_0141
db: UniProt

UnificationXref3386
type: UnificationXref
id: 5593728
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593728

UnificationXref3387
type: UnificationXref
id: MAL13P1.209
db: UniProt

UnificationXref3388
type: UnificationXref
id: 5593746
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593746

UnificationXref3389
type: UnificationXref
id: PF14_0230
db: UniProt

Synthesis of PC
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction152
pathway component: BiochemicalReaction151
pathway component: BiochemicalReaction150
pathway component: BiochemicalReaction145
pathway component: BiochemicalReaction153
evidence: Evidence293
xref: UnificationXref1727
xref: UnificationXref1728
xref: RelationshipXref269
pathway order: PathwayStep289
pathway order: PathwayStep288
pathway order: PathwayStep290
pathway order: PathwayStep280
pathway order: PathwayStep287
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref3381
type: UnificationXref
id: PF13_0129
db: UniProt

UnificationXref3380
type: UnificationXref
id: 5593764
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593764

UnificationXref3383
type: UnificationXref
id: PF11_0260
db: UniProt

UnificationXref3382
type: UnificationXref
id: 5593816
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593816

SequenceSite1631
type: SequenceSite
position status: EQUAL
sequence position: 953

SequenceSite1630
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2248
type: UnificationXref
id: 5593534
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593534

UnificationXref2249
type: UnificationXref
id: 5593537
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593537

SequenceSite1637
type: SequenceSite
position status: EQUAL
sequence position: 511

UnificationXref2244
type: UnificationXref
id: CHEBI:18290
db: ChEBI

SequenceSite1636
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2245
type: UnificationXref
id: 113547
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113547

UnificationXref3379
type: UnificationXref
id: PF14_0579
db: UniProt

SequenceSite1639
type: SequenceSite
position status: EQUAL
sequence position: 906

UnificationXref2246
type: UnificationXref
id: REACT_2518
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2518.3

UnificationXref3378
type: UnificationXref
id: 5593748
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593748

UniProt:PFI1090w
type: ProteinReference
xref: UnificationXref2917
organism: http://identifiers.org/taxonomy/5833

SequenceSite1638
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref2247
type: UnificationXref
id: PF11_0256
db: UniProt

UnificationXref3377
type: UnificationXref
id: PF13_0224
db: UniProt

SequenceSite1633
type: SequenceSite
position status: EQUAL
sequence position: 177

UnificationXref2240
type: UnificationXref
id: 29362
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29362

UnificationXref3376
type: UnificationXref
id: 5593783
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593783

SequenceSite1632
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2241
type: UnificationXref
id: REACT_2390
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2390.1

UnificationXref3375
type: UnificationXref
id: PF11_0438
db: UniProt

SequenceSite1635
type: SequenceSite
position status: EQUAL
sequence position: 874

UnificationXref159
type: UnificationXref
id: GO:0008021
db: GENE ONTOLOGY

UnificationXref2242
type: UnificationXref
id: PF14_0441
db: UniProt

UnificationXref3374
type: UnificationXref
id: 5593766
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593766

SequenceSite1634
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref158
type: UnificationXref
id: REACT_261535
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_261535.1

UnificationXref2243
type: UnificationXref
id: 5593536
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593536

UnificationXref3373
type: UnificationXref
id: PFF0885w
db: UniProt

UnificationXref167
type: UnificationXref
id: GO:0034774
db: GENE ONTOLOGY

UnificationXref3371
type: UnificationXref
id: PF11_0043
db: UniProt

UnificationXref168
type: UnificationXref
id: 216785
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=216785

UnificationXref3372
type: UnificationXref
id: 5593724
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593724

UnificationXref165
type: UnificationXref
id: 5595441
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595441

UnificationXref166
type: UnificationXref
id: REACT_246022
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_246022.1

UnificationXref3370
type: UnificationXref
id: 5593785
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593785

SequenceSite1629
type: SequenceSite
position status: EQUAL
sequence position: 1224

UnificationXref163
type: UnificationXref
id: 5595438
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595438

UnificationXref164
type: UnificationXref
id: 5595439
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595439

UnificationXref161
type: UnificationXref
id: REACT_21130
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_21130.2

UnificationXref162
type: UnificationXref
id: GO:0030672
db: GENE ONTOLOGY

UnificationXref160
type: UnificationXref
id: 437093
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=437093

SequenceSite1641
type: SequenceSite
position status: EQUAL
sequence position: 181

SequenceSite1640
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref2239
type: UnificationXref
id: REACT_4970
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4970.1

UnificationXref2237
type: UnificationXref
id: REACT_174157
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_174157.3

http://identifiers.org/pubmed/20435355
type: PublicationXref
id: 20435355
author: Palczewski, Krzysztof
db: Pubmed
title: Retinoids for treatment of retinal diseases
source: Trends Pharmacol. Sci. 31:284-95
year: 2010

UnificationXref2238
type: UnificationXref
id: 113526
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113526

UnificationXref2235
type: UnificationXref
id: 5595024
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595024

UnificationXref3367
type: UnificationXref
id: PF14_0231
db: UniProt

UnificationXref2236
type: UnificationXref
id: 5595026
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595026

UnificationXref3366
type: UnificationXref
id: 5593760
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593760

UnificationXref2233
type: UnificationXref
id: PF13_0223
db: UniProt

UnificationXref3369
type: UnificationXref
id: PF11_0106
db: UniProt

UnificationXref2234
type: UnificationXref
id: 5595021
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595021

UnificationXref3368
type: UnificationXref
id: 5593812
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593812

UnificationXref148
type: UnificationXref
id: 5595431
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595431

UnificationXref2231
type: UnificationXref
id: PF14_0671
db: UniProt

UnificationXref3363
type: UnificationXref
id: PFC0400w
db: UniProt

http://identifiers.org/pubmed/20462400
type: PublicationXref
id: 20462400
author: Henley, Jeremy M
author: Wilkinson, Kevin A
db: Pubmed
title: Mechanisms, regulation and consequences of protein SUMOylation
source: Biochem. J. 428:133-45
year: 2010

UnificationXref147
type: UnificationXref
id: REACT_21053
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_21053.2

UnificationXref2232
type: UnificationXref
id: 5595023
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595023

UnificationXref3362
type: UnificationXref
id: 5593787
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593787

UnificationXref3365
type: UnificationXref
id: PF13_0049
db: UniProt

UnificationXref149
type: UnificationXref
id: 5595433
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595433

UnificationXref2230
type: UnificationXref
id: REACT_4060
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4060.2

UnificationXref3364
type: UnificationXref
id: 5593726
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593726

UnificationXref154
type: UnificationXref
id: GO:0010008
db: GENE ONTOLOGY

UnificationXref155
type: UnificationXref
id: PF07_0065
db: UniProt

UnificationXref156
type: UnificationXref
id: 5595435
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595435

UnificationXref3360
type: UnificationXref
id: 5593814
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593814

UnificationXref157
type: UnificationXref
id: 5595437
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595437

UnificationXref3361
type: UnificationXref
id: MAL7P1.320
db: UniProt

UnificationXref150
type: UnificationXref
id: REACT_250225
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_250225.1

UnificationXref151
type: UnificationXref
id: GO:0031904
db: GENE ONTOLOGY

UnificationXref152
type: UnificationXref
id: 435350
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=435350

UnificationXref153
type: UnificationXref
id: REACT_20925
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_20925.2

UnificationXref2226
type: UnificationXref
id: REACT_263825
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_263825.1

UnificationXref2227
type: UnificationXref
id: 5593394
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593394

UnificationXref2228
type: UnificationXref
id: REACT_247761
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_247761.1

UnificationXref2229
type: UnificationXref
id: 113557
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113557

UnificationXref3359
type: UnificationXref
id: PFE0845c
db: UniProt

SequenceSite1611
type: SequenceSite
position status: EQUAL
sequence position: 222

UnificationXref139
type: UnificationXref
id: 1470067
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1470067

UnificationXref3354
type: UnificationXref
id: 5593740
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593740

SequenceSite1610
type: SequenceSite
position status: EQUAL
sequence position: 25

UnificationXref138
type: UnificationXref
id: 5595426
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595426

UnificationXref3353
type: UnificationXref
id: PF14_0296
db: UniProt

SequenceSite1613
type: SequenceSite
position status: EQUAL
sequence position: 222

UnificationXref137
type: UnificationXref
id: REACT_27452
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_27452.2

UnificationXref2220
type: UnificationXref
id: 5593387
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593387

UnificationXref3352
type: UnificationXref
id: 5593810
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593810

SequenceSite1612
type: SequenceSite
position status: EQUAL
sequence position: 25

UnificationXref136
type: UnificationXref
id: 1222286
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1222286

UnificationXref2221
type: UnificationXref
id: 5593388
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593388

UnificationXref3351
type: UnificationXref
id: PF13_0213
db: UniProt

SequenceSite1615
type: SequenceSite
position status: EQUAL
sequence position: 522

UnificationXref2222
type: UnificationXref
id: 5593389
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593389

UnificationXref3358
type: UnificationXref
id: 5593762
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593762

SequenceSite1614
type: SequenceSite
position status: EQUAL
sequence position: 44

UnificationXref2223
type: UnificationXref
id: 5593390
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593390

UnificationXref3357
type: UnificationXref
id: PFC0535w
db: UniProt

SequenceSite1617
type: SequenceSite
position status: EQUAL
sequence position: 105

UnificationXref2224
type: UnificationXref
id: 5593392
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593392

UnificationXref3356
type: UnificationXref
id: 5593722
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593722

http://identifiers.org/pubmed/19381358
type: PublicationXref
id: 19381358
author: Torti, FM
author: Shulaev, V
author: Mendes, P
author: Laubenbacher, R
author: Akman, S
author: Torti, SV
author: Hower, V
db: Pubmed
title: A general map of iron metabolism and tissue-specific subnetworks
source: Mol Biosyst 5:422-43
year: 2009

SequenceSite1616
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref2225
type: UnificationXref
id: 5593589
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593589

UnificationXref3355
type: UnificationXref
id: PF11_0313
db: UniProt

SequenceSite1607
type: SequenceSite
position status: EQUAL
sequence position: 334

UnificationXref141
type: UnificationXref
id: GO:0031902
db: GENE ONTOLOGY

SequenceSite1608
type: SequenceSite
position status: EQUAL
sequence position: 33

UnificationXref142
type: UnificationXref
id: PFE1185w
db: UniProt

SequenceSite1609
type: SequenceSite
position status: EQUAL
sequence position: 334

UnificationXref140
type: UnificationXref
id: REACT_111691
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_111691.1

UnificationXref145
type: UnificationXref
id: REACT_238561
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_238561.1

UnificationXref146
type: UnificationXref
id: 435347
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=435347

UnificationXref3350
type: UnificationXref
id: 5593742
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593742

UnificationXref143
type: UnificationXref
id: 5595428
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595428

UnificationXref144
type: UnificationXref
id: 5595430
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595430

http://identifiers.org/pubmed/17846176
type: PublicationXref
id: 17846176
author: Baas, PW
author: Myers, KA
db: Pubmed
title: Kinesin-5 regulates the growth of the axon by acting as a brake on its microtubule array
source: J Cell Biol 178:1081-91
year: 2007

UnificationXref2217
type: UnificationXref
id: 5593379
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593379

UnificationXref3349
type: UnificationXref
id: PFD0770c
db: UniProt

UnificationXref2218
type: UnificationXref
id: 5593381
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593381

UnificationXref3348
type: UnificationXref
id: 5593768
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593768

UnificationXref2215
type: UnificationXref
id: REACT_4026
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4026.2

UnificationXref2216
type: UnificationXref
id: 5593377
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593377

SequenceSite1620
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref2219
type: UnificationXref
id: 5593382
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593382

SequenceSite1624
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref126
type: UnificationXref
id: REACT_3428
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3428.2

UnificationXref3341
type: UnificationXref
id: 5597037
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597037

SequenceSite1623
type: SequenceSite
position status: EQUAL
sequence position: 198

UnificationXref125
type: UnificationXref
id: 71067
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=71067

UnificationXref2210
type: UnificationXref
id: REACT_192706
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192706.3

UnificationXref3340
type: UnificationXref
id: REACT_192692
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192692.3

SequenceSite1622
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref128
type: UnificationXref
id: 29418
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29418

UnificationXref3343
type: UnificationXref
id: 5596851
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596851

SequenceSite1621
type: SequenceSite
position status: EQUAL
sequence position: 199

UnificationXref127
type: UnificationXref
id: CHEBI:18291
db: ChEBI

UnificationXref3342
type: UnificationXref
id: REACT_192670
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192670.3

SequenceSite1628
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2213
type: UnificationXref
id: CHEBI:422
db: ChEBI

UnificationXref3345
type: UnificationXref
id: PF13_0268
db: UniProt

SequenceSite1627
type: SequenceSite
position status: EQUAL
sequence position: 214

UnificationXref129
type: UnificationXref
id: REACT_4937
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4937.2

UnificationXref2214
type: UnificationXref
id: 29708
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29708

UnificationXref3344
type: UnificationXref
id: REACT_263512
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_263512.1

SequenceSite1626
type: SequenceSite
position status: EQUAL
sequence position: 53

UnificationXref2211
type: UnificationXref
id: 5596930
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596930

UnificationXref3347
type: UnificationXref
id: PF14_0575a
db: UniProt

SequenceSite1625
type: SequenceSite
position status: EQUAL
sequence position: 198

UnificationXref2212
type: UnificationXref
id: REACT_192711
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192711.3

UnificationXref3346
type: UnificationXref
id: 5593744
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593744

SequenceSite1618
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref130
type: UnificationXref
id: 5595425
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595425

SequenceSite1619
type: SequenceSite
position status: EQUAL
sequence position: 199

UnificationXref131
type: UnificationXref
id: GO:0097013
db: GENE ONTOLOGY

UnificationXref132
type: UnificationXref
id: 1562549
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1562549

UnificationXref133
type: UnificationXref
id: REACT_111498
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_111498.1

UnificationXref134
type: UnificationXref
id: 1562550
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1562550

http://identifiers.org/pubmed/20807551
type: PublicationXref
id: 20807551
author: Noël, Jacques
author: Diochot, Sylvie
author: Baron, Anne
author: Deval, Emmanuel
author: Gasull, Xavier
author: Salinas, Miguel
author: Lingueglia, Eric
db: Pubmed
title: Acid-sensing ion channels (ASICs): pharmacology and implication in pain
source: Pharmacol. Ther. 128:549-58
year: 2010

UnificationXref135
type: UnificationXref
id: REACT_111721
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_111721.1

http://identifiers.org/pubmed/10648173
type: PublicationXref
id: 10648173
author: Menear, K
author: Baldock, D
author: Graff, P
author: Jones, CE
author: Akhlaq, M
author: Graham, B
db: Pubmed
title: Purification and characterization of human Syk produced using a baculovirus expression system
source: Protein Expr Purif 18:86-94
year: 2000

http://identifiers.org/pubmed/14091597
type: PublicationXref
id: 14091597
author: Lamy, M
author: MARIE, J
author: MAROTEAUX, P
author: Leveque, B
db: Pubmed
title: [A NEW DYSOSTOSIS WITH URINARY ELIMINATION OF CHONDROITIN SULFATE B]
source: Presse Med 71:1849-52
year: 1963

http://identifiers.org/pubmed/19261456
type: PublicationXref
id: 19261456
author: Procko, E
author: Gaudet, R
db: Pubmed
title: Antigen processing and presentation: TAPping into ABC transporters
source: Curr Opin Immunol 21:84-91
year: 2009

MLCL
type: SmallMoleculeReference
name: lysoDPG
name: Monolysocardiolipin
name: monolyso cardiolipin [ChEBI:60430]
name: monolysoDPG
name: monolyso cardiolipin
xref: UnificationXref1791

Stoichiometry424
type: Stoichiometry
physical entity: Protein367
stoichiometric coefficient: 1.0

Stoichiometry423
type: Stoichiometry
physical entity: Protein366
stoichiometric coefficient: 1.0

Stoichiometry426
type: Stoichiometry
physical entity: SmallMolecule510
stoichiometric coefficient: 1.0

Stoichiometry425
type: Stoichiometry
physical entity: SmallMolecule510
stoichiometric coefficient: 2.0

Stoichiometry420
type: Stoichiometry
physical entity: Protein359
stoichiometric coefficient: 1.0

Stoichiometry422
type: Stoichiometry
physical entity: Protein365
stoichiometric coefficient: 1.0

Stoichiometry421
type: Stoichiometry
physical entity: Protein364
stoichiometric coefficient: 1.0

UnificationXref5581
type: UnificationXref
id: 5595087
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595087

UnificationXref5580
type: UnificationXref
id: 5595086
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595086

UnificationXref5583
type: UnificationXref
id: REACT_231137
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_231137.1

UnificationXref5582
type: UnificationXref
id: 5595089
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595089

Stoichiometry428
type: Stoichiometry
physical entity: Protein377
stoichiometric coefficient: 2.0

Stoichiometry427
type: Stoichiometry
physical entity: Protein369
stoichiometric coefficient: 1.0

Stoichiometry429
type: Stoichiometry
physical entity: 14-3-3zeta dimer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

UnificationXref5588
type: UnificationXref
id: 5595091
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595091

UnificationXref5589
type: UnificationXref
id: 5595092
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595092

UnificationXref5584
type: UnificationXref
id: CHEBI:29182
db: ChEBI

UnificationXref5585
type: UnificationXref
id: 379743
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379743

UnificationXref5586
type: UnificationXref
id: REACT_23144
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_23144.1

UnificationXref5587
type: UnificationXref
id: MAL8P1.125
db: UniProt

Stoichiometry415
type: Stoichiometry
physical entity: SmallMolecule505
stoichiometric coefficient: 1.0

Stoichiometry414
type: Stoichiometry
physical entity: FDX1L (oxidized) (name copied from entity in Homo sapiens)
stoichiometric coefficient: 2.0

Stoichiometry413
type: Stoichiometry
physical entity: SmallMolecule504
stoichiometric coefficient: 1.0

Stoichiometry412
type: Stoichiometry
physical entity: Protein356
stoichiometric coefficient: 1.0

Stoichiometry411
type: Stoichiometry
physical entity: Protein355
stoichiometric coefficient: 1.0

MPS VI - Maroteaux-Lamy syndrome
type: Pathway
data source: Provenance1
pathway component: REACT 250358.1
evidence: Evidence102
xref: UnificationXref601
xref: UnificationXref600
pathway order: PathwayStep92
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

Stoichiometry410
type: Stoichiometry
physical entity: SmallMolecule208
stoichiometric coefficient: 1.0

UnificationXref5594
type: UnificationXref
id: REACT_15833
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15833.1

UnificationXref5593
type: UnificationXref
id: 379793
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379793

UnificationXref5592
type: UnificationXref
id: CHEBI:29183
db: ChEBI

UnificationXref5591
type: UnificationXref
id: REACT_77273
db: Reactome
id version: 4
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_77273.4

UnificationXref5590
type: UnificationXref
id: 5595094
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595094

Stoichiometry419
type: Stoichiometry
physical entity: PhysicalEntity11
stoichiometric coefficient: 1.0

Stoichiometry418
type: Stoichiometry
physical entity: SmallMolecule313
stoichiometric coefficient: 2.0

Stoichiometry417
type: Stoichiometry
physical entity: FDX1L (reduced) (name copied from entity in Homo sapiens)
stoichiometric coefficient: 2.0

UniProt:PFF1155w
type: ProteinReference
xref: UnificationXref79
organism: http://identifiers.org/taxonomy/5833

Stoichiometry416
type: Stoichiometry
physical entity: Protein356
stoichiometric coefficient: 1.0

di-mu-sulfido-diiron(2+) [ChEBI:33737]
type: SmallMoleculeReference
name: [Fe2S2](2+)
name: [2Fe-2S](2+)
name: di-mu-sulfido-diiron(2+)
name: [Fe2(mu-S)2](2+)
xref: UnificationXref3137

http://identifiers.org/pubmed/47244
type: PublicationXref
id: 47244
author: Cash, JD
author: Pepper, DS
author: Moore, S
db: Pubmed
title: The isolation and characterisation of a platelet-specific beta-globulin (beta-thromboglobulin) and the detection of antiurokinase and antiplasmin released from thrombin-aggregated washed human platelets
source: Biochim Biophys Acta 379:360-9
year: 1975

UnificationXref5599
type: UnificationXref
id: PFC0710w.2
db: UniProt

UnificationXref5597
type: UnificationXref
id: 5595120
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595120

UnificationXref5598
type: UnificationXref
id: REACT_254486
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_254486.1

[Fe2S2](+)
type: SmallMoleculeReference
name: di-mu-sulfido-diiron(1+)
name: [2Fe-2S](1+)
name: di-mu-sulfido-diiron(1+) [ChEBI:33738]
name: [Fe2(mu-S)2](+)
xref: UnificationXref3141

UnificationXref5595
type: UnificationXref
id: PF14_0589
db: UniProt

UnificationXref5596
type: UnificationXref
id: 5595118
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595118

http://identifiers.org/pubmed/4358634
type: PublicationXref
id: 4358634
author: Roth, DG
author: Deuel, TF
author: Shelton, E
db: Pubmed
title: Purification and properties of phosphoribosyl pyrophosphate synthetase from rat liver
source: J Biol Chem 249:291-296
year: 1974

http://identifiers.org/pubmed/21479626
type: PublicationXref
id: 21479626
author: Sass, JO
db: Pubmed
title: Inborn errors of ketogenesis and ketone body utilization
source: J Inherit Metab Dis
year: 2011

Stoichiometry442
type: Stoichiometry
physical entity: Protein399
stoichiometric coefficient: 1.0

Stoichiometry441
type: Stoichiometry
physical entity: Protein398
stoichiometric coefficient: 1.0

Stoichiometry444
type: Stoichiometry
physical entity: Protein401
stoichiometric coefficient: 1.0

Stoichiometry443
type: Stoichiometry
physical entity: Protein400
stoichiometric coefficient: 1.0

Stoichiometry446
type: Stoichiometry
physical entity: Protein403
stoichiometric coefficient: 1.0

Stoichiometry445
type: Stoichiometry
physical entity: Protein402
stoichiometric coefficient: 1.0

Stoichiometry448
type: Stoichiometry
physical entity: Protein405
stoichiometric coefficient: 1.0

Stoichiometry447
type: Stoichiometry
physical entity: Protein404
stoichiometric coefficient: 2.0

Stoichiometry449
type: Stoichiometry
physical entity: Protein406
stoichiometric coefficient: 1.0

UnificationXref5561
type: UnificationXref
id: 379762
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379762

UnificationXref5560
type: UnificationXref
id: CHEBI:29179
db: ChEBI

UnificationXref5562
type: UnificationXref
id: REACT_16106
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_16106.1

UnificationXref5563
type: UnificationXref
id: PF07_0073
db: UniProt

UnificationXref5564
type: UnificationXref
id: 5595098
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595098

UnificationXref5565
type: UnificationXref
id: 5595099
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595099

UnificationXref5566
type: UnificationXref
id: 5595101
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595101

UnificationXref5567
type: UnificationXref
id: REACT_236542
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_236542.1

endosome membrane
type: CellularLocationVocabulary
xref: UnificationXref154

UnificationXref5568
type: UnificationXref
id: CHEBI:29180
db: ChEBI

UnificationXref5569
type: UnificationXref
id: 379749
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379749

Stoichiometry450
type: Stoichiometry
physical entity: Protein407
stoichiometric coefficient: 1.0

Stoichiometry451
type: Stoichiometry
physical entity: Protein408
stoichiometric coefficient: 1.0

Stoichiometry433
type: Stoichiometry
physical entity: Protein395
stoichiometric coefficient: 4.0

Stoichiometry432
type: Stoichiometry
physical entity: Protein394
stoichiometric coefficient: 1.0

Stoichiometry431
type: Stoichiometry
physical entity: Protein393
stoichiometric coefficient: 1.0

Stoichiometry430
type: Stoichiometry
physical entity: Protein378
stoichiometric coefficient: 1.0

Stoichiometry437
type: Stoichiometry
physical entity: Protein397
stoichiometric coefficient: 2.0

Stoichiometry436
type: Stoichiometry
physical entity: Protein396
stoichiometric coefficient: 2.0

http://identifiers.org/pubmed/2531289
type: PublicationXref
id: 2531289
author: Sugimura, A
author: Hagiya, M
author: Shimizu, S
author: Shimonishi, M
author: Seki, T
author: Tashiro, K
author: Nishizawa, T
author: Nakamura, T
db: Pubmed
title: Molecular cloning and expression of human hepatocyte growth factor
source: Nature 342:440-3
year: 1989

Stoichiometry435
type: Stoichiometry
physical entity: Protein396
stoichiometric coefficient: 2.0

Stoichiometry434
type: Stoichiometry
physical entity: Protein395
stoichiometric coefficient: 4.0

Stoichiometry439
type: Stoichiometry
physical entity: PhysicalEntity12
stoichiometric coefficient: 1.0

Stoichiometry438
type: Stoichiometry
physical entity: Protein397
stoichiometric coefficient: 2.0

UnificationXref5572
type: UnificationXref
id: 5595111
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595111

UnificationXref5571
type: UnificationXref
id: PF11_0270
db: UniProt

UnificationXref5570
type: UnificationXref
id: REACT_15966
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15966.1

UnificationXref5575
type: UnificationXref
id: REACT_174140
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_174140.3

UnificationXref5576
type: UnificationXref
id: CHEBI:29181
db: ChEBI

UnificationXref5573
type: UnificationXref
id: 5595112
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595112

UnificationXref5574
type: UnificationXref
id: 5595114
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595114

UnificationXref5579
type: UnificationXref
id: PF13_0205
db: UniProt

UnificationXref5577
type: UnificationXref
id: 379763
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379763

http://identifiers.org/pubmed/13679574
type: PublicationXref
id: 13679574
author: Bouvier, M
author: Rousseau, G
author: Angers, S
author: Charest, PG
author: Kohout, T
author: Azzi, M
author: Piñeyro, G
db: Pubmed
title: Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors
source: Proc Natl Acad Sci U S A 100:11406-11
year: 2003

UnificationXref5578
type: UnificationXref
id: REACT_15882
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15882.1

http://identifiers.org/pubmed/11123943
type: PublicationXref
id: 11123943
author: Klee, C B
author: Yang, S A
db: Pubmed
title: Low affinity Ca2+-binding sites of calcineurin B mediate conformational changes in calcineurin A
source: Biochemistry 39:16147-54
year: 2000

Stoichiometry440
type: Stoichiometry
physical entity: Kinesins
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/21903638
type: PublicationXref
id: 21903638
author: De, Antara
db: Pubmed
title: Wnt/Ca2+ signaling pathway: a brief overview
source: Acta Biochim. Biophys. Sin. (Shanghai) 43:745-56
year: 2011

http://identifiers.org/pubmed/14988808
type: PublicationXref
id: 14988808
author: Jakobs, C
author: Huck, JH
author: Verhoeven, NM
author: van der Knaap, MS
author: Struys, EA
author: Salomons, GS
db: Pubmed
title: Ribose-5-phosphate isomerase deficiency: new inborn error in the pentose phosphate pathway associated with a slowly progressive leukoencephalopathy
source: Am J Hum Genet 74:745-51
year: 2004

Stoichiometry467
type: Stoichiometry
physical entity: Protein423
stoichiometric coefficient: 1.0

Stoichiometry468
type: Stoichiometry
physical entity: Protein424
stoichiometric coefficient: 1.0

Stoichiometry469
type: Stoichiometry
physical entity: Protein425
stoichiometric coefficient: 1.0

Stoichiometry463
type: Stoichiometry
physical entity: Protein420
stoichiometric coefficient: 1.0

Stoichiometry464
type: Stoichiometry
physical entity: PhysicalEntity2
stoichiometric coefficient: 7.0

Stoichiometry465
type: Stoichiometry
physical entity: Protein421
stoichiometric coefficient: 1.0

Stoichiometry466
type: Stoichiometry
physical entity: Protein422
stoichiometric coefficient: 1.0

UniProt:PFC0400w
type: ProteinReference
xref: UnificationXref3363
organism: http://identifiers.org/taxonomy/5833

Stoichiometry471
type: Stoichiometry
physical entity: Protein427
stoichiometric coefficient: 1.0

Stoichiometry470
type: Stoichiometry
physical entity: Protein426
stoichiometric coefficient: 1.0

UnificationXref4419
type: UnificationXref
id: REACT_215034
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_215034.2

Stoichiometry473
type: Stoichiometry
physical entity: Protein429
stoichiometric coefficient: 1.0

Stoichiometry472
type: Stoichiometry
physical entity: Protein428
stoichiometric coefficient: 1.0

UnificationXref5549
type: UnificationXref
id: REACT_253924
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253924.1

UnificationXref4417
type: UnificationXref
id: REACT_111524
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_111524.1

http://identifiers.org/pubmed/14559994
type: PublicationXref
id: 14559994
author: Iwakoshi, NN
author: Lee, AH
author: Glimcher, LH
db: Pubmed
title: XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response
source: Mol Cell Biol 23:7448-59
year: 2003

UnificationXref5548
type: UnificationXref
id: 5595116
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595116

UnificationXref4418
type: UnificationXref
id: 5595898
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595898

UnificationXref4415
type: UnificationXref
id: REACT_192689
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192689.3

alpha-Linolenic acid [ChEBI:10298]
type: SmallMoleculeReference
name: alpha-Linolenic acid
name: Linolenate
name: 9,12,15-Octadecatrienoic acid
name: alpha-Linolenate
xref: UnificationXref1884

UnificationXref4416
type: UnificationXref
id: 1236719
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1236719

Synthesis and interconversion of nucleotide di- and triphosphates
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction239
pathway component: BiochemicalReaction238
pathway component: BiochemicalReaction228
pathway component: BiochemicalReaction227
pathway component: BiochemicalReaction229
pathway component: BiochemicalReaction243
pathway component: BiochemicalReaction225
pathway component: BiochemicalReaction234
pathway component: BiochemicalReaction244
pathway component: BiochemicalReaction226
pathway component: BiochemicalReaction235
pathway component: BiochemicalReaction241
pathway component: BiochemicalReaction236
pathway component: BiochemicalReaction242
pathway component: BiochemicalReaction237
pathway component: BiochemicalReaction230
pathway component: BiochemicalReaction231
pathway component: BiochemicalReaction232
pathway component: BiochemicalReaction233
pathway component: BiochemicalReaction240
evidence: Evidence428
xref: RelationshipXref423
xref: UnificationXref2684
xref: UnificationXref2685
pathway order: PathwayStep422
pathway order: PathwayStep423
pathway order: PathwayStep420
pathway order: PathwayStep421
pathway order: PathwayStep406
pathway order: PathwayStep419
pathway order: PathwayStep407
pathway order: PathwayStep417
pathway order: PathwayStep408
pathway order: PathwayStep424
pathway order: PathwayStep418
pathway order: PathwayStep409
pathway order: PathwayStep416
pathway order: PathwayStep415
pathway order: PathwayStep405
pathway order: PathwayStep414
pathway order: PathwayStep413
pathway order: PathwayStep412
pathway order: PathwayStep411
pathway order: PathwayStep410
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref5545
type: UnificationXref
id: CHEBI:29185
db: ChEBI

UnificationXref4413
type: UnificationXref
id: REACT_206766
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_206766.2

UnificationXref5544
type: UnificationXref
id: REACT_245419
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_245419.1

UnificationXref4414
type: UnificationXref
id: 5597049
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597049

UnificationXref5547
type: UnificationXref
id: REACT_15975
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15975.1

UnificationXref4411
type: UnificationXref
id: REACT_111624
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_111624.2

UnificationXref5546
type: UnificationXref
id: 379776
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379776

UnificationXref4412
type: UnificationXref
id: 5595896
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595896

UnificationXref5541
type: UnificationXref
id: 379771
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379771

UnificationXref5540
type: UnificationXref
id: CHEBI:29169
db: ChEBI

UnificationXref4410
type: UnificationXref
id: 1236918
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1236918

UnificationXref5543
type: UnificationXref
id: 5595084
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595084

http://identifiers.org/pubmed/9883897
type: PublicationXref
id: 9883897
author: Csere, P
author: Lill, R
author: Kispal, G
db: Pubmed
title: Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p
source: FEBS Lett 441:266-70
year: 1998

UnificationXref5542
type: UnificationXref
id: REACT_15877
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15877.1

http://identifiers.org/pubmed/13538944
type: PublicationXref
id: 13538944
author: Tsuboi, KK
author: Hudson, PB
author: Estrada, J
db: Pubmed
title: Enzymes of the human erythrocyte. IV. Phosphoglucose isomerase, purification and properties.
source: J Biol Chem 231:19-29
year: 1958

UnificationXref5550
type: UnificationXref
id: CHEBI:29173
db: ChEBI

Stoichiometry458
type: Stoichiometry
physical entity: Protein415
stoichiometric coefficient: 1.0

Stoichiometry459
type: Stoichiometry
physical entity: Protein416
stoichiometric coefficient: 1.0

Stoichiometry456
type: Stoichiometry
physical entity: Protein413
stoichiometric coefficient: 1.0

Stoichiometry457
type: Stoichiometry
physical entity: Protein414
stoichiometric coefficient: 1.0

Stoichiometry454
type: Stoichiometry
physical entity: Protein411
stoichiometric coefficient: 1.0

Stoichiometry455
type: Stoichiometry
physical entity: Protein412
stoichiometric coefficient: 1.0

Stoichiometry452
type: Stoichiometry
physical entity: Protein409
stoichiometric coefficient: 1.0

Stoichiometry453
type: Stoichiometry
physical entity: Protein410
stoichiometric coefficient: 1.0

Stoichiometry462
type: Stoichiometry
physical entity: Protein419
stoichiometric coefficient: 1.0

Stoichiometry461
type: Stoichiometry
physical entity: Protein418
stoichiometric coefficient: 1.0

Stoichiometry460
type: Stoichiometry
physical entity: Protein417
stoichiometric coefficient: 1.0

UnificationXref4426
type: UnificationXref
id: 2213225
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2213225

UnificationXref4427
type: UnificationXref
id: REACT_124109
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_124109.1

UnificationXref4428
type: UnificationXref
id: 2213226
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2213226

UnificationXref5559
type: UnificationXref
id: REACT_233669
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_233669.1

UnificationXref4429
type: UnificationXref
id: REACT_125085
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_125085.1

UnificationXref5558
type: UnificationXref
id: 5595073
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595073

UnificationXref4422
type: UnificationXref
id: 5597050
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597050

IRS-mediated signalling
type: Pathway
data source: Provenance1
pathway component: REACT 239272.1
evidence: Evidence767
xref: UnificationXref4570
xref: UnificationXref4569
pathway order: PathwayStep747
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref5557
type: UnificationXref
id: REACT_15779
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15779.1

UnificationXref4423
type: UnificationXref
id: REACT_192688
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192688.3

UnificationXref5556
type: UnificationXref
id: 379768
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379768

UnificationXref4424
type: UnificationXref
id: 5597046
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597046

UnificationXref5555
type: UnificationXref
id: CHEBI:29177
db: ChEBI

UnificationXref4425
type: UnificationXref
id: REACT_192694
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192694.3

UnificationXref5554
type: UnificationXref
id: REACT_230422
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_230422.1

UnificationXref5553
type: UnificationXref
id: 5595105
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595105

UnificationXref5552
type: UnificationXref
id: REACT_15914
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15914.1

UnificationXref4420
type: UnificationXref
id: 5597051
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597051

UnificationXref5551
type: UnificationXref
id: 379742
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379742

UnificationXref4421
type: UnificationXref
id: REACT_192713
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192713.3

http://identifiers.org/pubmed/14530973
type: PublicationXref
id: 14530973
author: Mackenzie, B
author: Hediger, MA
db: Pubmed
title: SLC11 family of H+-coupled metal-ion transporters NRAMP1 and DMT1
source: Pflugers Arch 447:571-9
year: 2004

Stoichiometry485
type: Stoichiometry
physical entity: Protein443
stoichiometric coefficient: 1.0

Stoichiometry486
type: Stoichiometry
physical entity: Protein398
stoichiometric coefficient: 1.0

Stoichiometry487
type: Stoichiometry
physical entity: Protein399
stoichiometric coefficient: 1.0

Sphingolipid de novo biosynthesis
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction189
pathway component: BiochemicalReaction190
evidence: Evidence350
xref: UnificationXref2067
xref: RelationshipXref328
xref: UnificationXref2068
pathway order: PathwayStep346
pathway order: PathwayStep347
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

Stoichiometry488
type: Stoichiometry
physical entity: Protein400
stoichiometric coefficient: 1.0

Stoichiometry489
type: Stoichiometry
physical entity: Protein401
stoichiometric coefficient: 1.0

UnificationXref5527
type: UnificationXref
id: REACT_237643
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_237643.1

UnificationXref5526
type: UnificationXref
id: 5595125
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595125

UnificationXref5529
type: UnificationXref
id: 379758
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379758

Stoichiometry491
type: Stoichiometry
physical entity: Protein403
stoichiometric coefficient: 1.0

UnificationXref5528
type: UnificationXref
id: CHEBI:29178
db: ChEBI

Stoichiometry490
type: Stoichiometry
physical entity: Protein402
stoichiometric coefficient: 1.0

Stoichiometry493
type: Stoichiometry
physical entity: Protein405
stoichiometric coefficient: 1.0

Stoichiometry492
type: Stoichiometry
physical entity: Protein404
stoichiometric coefficient: 2.0

Stoichiometry495
type: Stoichiometry
physical entity: Protein407
stoichiometric coefficient: 1.0

Stoichiometry494
type: Stoichiometry
physical entity: Protein406
stoichiometric coefficient: 1.0

UnificationXref5521
type: UnificationXref
id: 379766
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379766

UnificationXref5520
type: UnificationXref
id: CHEBI:29176
db: ChEBI

UnificationXref5523
type: UnificationXref
id: PF14_0198
db: UniProt

UnificationXref5522
type: UnificationXref
id: REACT_15638
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15638.1

UnificationXref5525
type: UnificationXref
id: 5595123
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595123

UnificationXref5524
type: UnificationXref
id: 5595122
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595122

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction342
evidence: Evidence643
xref: UnificationXref4050
xref: UnificationXref4051
pathway order: PathwayStep627
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/13828999
type: PublicationXref
id: 13828999
author: KANTERO, I
author: KUHLBACK, B
author: GORDIN, R
author: GRASBECK, R
db: Pubmed
title: Selective vitamin B12 malabsorption and proteinuria in young people. A syndrome
source: Acta Med Scand 167:289-96
year: 1960

Stoichiometry476
type: Stoichiometry
physical entity: Protein432
stoichiometric coefficient: 1.0

Stoichiometry477
type: Stoichiometry
physical entity: Protein433
stoichiometric coefficient: 1.0

Stoichiometry474
type: Stoichiometry
physical entity: Protein430
stoichiometric coefficient: 1.0

Stoichiometry475
type: Stoichiometry
physical entity: Protein431
stoichiometric coefficient: 1.0

Stoichiometry478
type: Stoichiometry
physical entity: Protein434
stoichiometric coefficient: 1.0

Stoichiometry479
type: Stoichiometry
physical entity: Protein435
stoichiometric coefficient: 1.0

UnificationXref4404
type: UnificationXref
id: REACT_2965
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2965.2

Stoichiometry480
type: Stoichiometry
physical entity: Protein436
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/9331217
type: PublicationXref
id: 9331217
author: Cooper, JA
author: Hart, MC
author: Korshunova, YO
db: Pubmed
title: Vertebrates have conserved capping protein alpha isoforms with specific expression patterns
source: Cell Motil Cytoskeleton 38:120-32
year: 1997

http://identifiers.org/pubmed/18243674
type: PublicationXref
id: 18243674
author: Purcell, AW
author: Elliott, T
db: Pubmed
title: Molecular machinations of the MHC-I peptide loading complex
source: Curr Opin Immunol 20:75-81
year: 2008

UnificationXref5539
type: UnificationXref
id: REACT_234618
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_234618.1

UnificationXref4405
type: UnificationXref
id: 5595314
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595314

UnificationXref5538
type: UnificationXref
id: 5595082
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595082

UnificationXref4406
type: UnificationXref
id: 5595820
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595820

UnificationXref5537
type: UnificationXref
id: REACT_17479
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17479.1

UnificationXref4407
type: UnificationXref
id: REACT_227839
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_227839.2

UnificationXref4408
type: UnificationXref
id: 5597045
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597045

Stoichiometry484
type: Stoichiometry
physical entity: Protein442
stoichiometric coefficient: 1.0

UnificationXref4409
type: UnificationXref
id: REACT_192695
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192695.3

Stoichiometry483
type: Stoichiometry
physical entity: Protein441
stoichiometric coefficient: 1.0

Stoichiometry482
type: Stoichiometry
physical entity: Protein438
stoichiometric coefficient: 1.0

Stoichiometry481
type: Stoichiometry
physical entity: Protein437
stoichiometric coefficient: 1.0

UnificationXref5532
type: UnificationXref
id: 5595042
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595042

UnificationXref5531
type: UnificationXref
id: PF14_0428
db: UniProt

UnificationXref5530
type: UnificationXref
id: REACT_15991
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15991.1

UnificationXref5536
type: UnificationXref
id: 379739
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379739

UnificationXref4400
type: UnificationXref
id: 29506
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29506

UnificationXref5535
type: UnificationXref
id: CHEBI:29174
db: ChEBI

UnificationXref4401
type: UnificationXref
id: REACT_2616
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2616.2

UnificationXref5534
type: UnificationXref
id: REACT_206140
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_206140.2

UnificationXref4402
type: UnificationXref
id: CHEBI:16414
db: ChEBI

UnificationXref5533
type: UnificationXref
id: 5595044
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595044

UnificationXref4403
type: UnificationXref
id: 29702
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29702

UnificationXref5502
type: UnificationXref
id: CHEBI:29167
db: ChEBI

UnificationXref4456
type: UnificationXref
id: REACT_259176
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_259176.1

UnificationXref5503
type: UnificationXref
id: 379725
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379725

UnificationXref4455
type: UnificationXref
id: 5597035
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597035

UnificationXref5500
type: UnificationXref
id: 5595075
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595075

UnificationXref4458
type: UnificationXref
id: 5595712
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595712

UnificationXref5501
type: UnificationXref
id: REACT_231520
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_231520.1

UnificationXref4457
type: UnificationXref
id: PFI0960w
db: UniProt

UnificationXref4452
type: UnificationXref
id: REACT_254048
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_254048.1

UnificationXref4451
type: UnificationXref
id: 5597033
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597033

UnificationXref4454
type: UnificationXref
id: REACT_249357
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_249357.1

UnificationXref4453
type: UnificationXref
id: 5597034
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597034

UnificationXref5508
type: UnificationXref
id: 5595080
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595080

UnificationXref5509
type: UnificationXref
id: REACT_236584
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_236584.1

UnificationXref5506
type: UnificationXref
id: 5595077
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595077

UnificationXref5507
type: UnificationXref
id: 5595078
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595078

UnificationXref4459
type: UnificationXref
id: CHEBI:16670
db: ChEBI

UnificationXref5504
type: UnificationXref
id: REACT_15645
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15645.1

http://identifiers.org/pubmed/19230644
type: PublicationXref
id: 19230644
author: Tammela, Tuomas
author: Bry, Maija
author: Alitalo, K
author: Lohela, Marja
db: Pubmed
title: VEGFs and receptors involved in angiogenesis versus lymphangiogenesis
source: Curr. Opin. Cell Biol. 21:154-65
year: 2009

UnificationXref5505
type: UnificationXref
id: PF10_0149
db: UniProt

SequenceSite181
type: SequenceSite
position status: EQUAL
sequence position: 364

SequenceSite182
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite180
type: SequenceSite
position status: EQUAL
sequence position: 2

Switching of origins to a post-replicative state
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction321
pathway component: REACT 236500.1
pathway component: REACT 263437.1
evidence: Evidence571
xref: UnificationXref3770
xref: UnificationXref3769
pathway order: PathwayStep560
pathway order: PathwayStep555
pathway order: PathwayStep559
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

SequenceSite185
type: SequenceSite
position status: EQUAL
sequence position: 286

SequenceSite186
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite183
type: SequenceSite
position status: EQUAL
sequence position: 286

UnificationXref4450
type: UnificationXref
id: REACT_240831
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_240831.1

SequenceSite184
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite189
type: SequenceSite
position status: EQUAL
sequence position: 408

SequenceSite187
type: SequenceSite
position status: EQUAL
sequence position: 335

SequenceSite188
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref5511
type: UnificationXref
id: 379778
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379778

UnificationXref4469
type: UnificationXref
id: 5595710
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595710

UnificationXref5512
type: UnificationXref
id: REACT_16086
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_16086.1

UnificationXref4468
type: UnificationXref
id: 5595709
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595709

UnificationXref5513
type: UnificationXref
id: 5595067
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595067

UnificationXref4467
type: UnificationXref
id: REACT_24806
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_24806.1

http://identifiers.org/pubmed/16314626
type: PublicationXref
id: 16314626
author: Forastiere, AA
author: Goldwasser, MA
author: Eastern Cooperative Oncology, Group
author: Burtness, B
author: Mattar, B
author: Flood, W
db: Pubmed
title: Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: an Eastern Cooperative Oncology Group study
source: J Clin Oncol 23:8646-54
year: 2005

UnificationXref5514
type: UnificationXref
id: REACT_241671
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_241671.1

UnificationXref4466
type: UnificationXref
id: 938699
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=938699

UnificationXref4465
type: UnificationXref
id: CHEBI:60125
db: ChEBI

UnificationXref4464
type: UnificationXref
id: REACT_24449
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_24449.1

UnificationXref4463
type: UnificationXref
id: 879473
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=879473

UnificationXref5510
type: UnificationXref
id: CHEBI:29175
db: ChEBI

UnificationXref4462
type: UnificationXref
id: CHEBI:53014
db: ChEBI

UnificationXref5519
type: UnificationXref
id: REACT_230225
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_230225.1

UnificationXref5515
type: UnificationXref
id: CHEBI:29168
db: ChEBI

UnificationXref5516
type: UnificationXref
id: 379748
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379748

UnificationXref5517
type: UnificationXref
id: REACT_16123
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_16123.1

UnificationXref5518
type: UnificationXref
id: 5595096
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595096

SequenceSite190
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite191
type: SequenceSite
position status: EQUAL
sequence position: 417

SequenceSite192
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite193
type: SequenceSite
position status: EQUAL
sequence position: 254

UnificationXref4460
type: UnificationXref
id: 879484
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=879484

SequenceSite194
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref4461
type: UnificationXref
id: REACT_24248
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_24248.2

SequenceSite195
type: SequenceSite
position status: EQUAL
sequence position: 253

SequenceSite196
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite197
type: SequenceSite
position status: EQUAL
sequence position: 434

SequenceSite198
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite199
type: SequenceSite
position status: EQUAL
sequence position: 434

Acetaminophen glutathion
type: SmallMoleculeReference
name: AA-Gsh
name: AA-Glutathion
name: acetaminophen glutathione conjugate
name: Glutathione-S-acetaminophen conjugate
name: 3-(Glutathion-S-yl)acetaminophen
name: acetaminophen glutathione conjugate [ChEBI:32639]
xref: UnificationXref3093

UnificationXref4430
type: UnificationXref
id: PF14_0553
db: UniProt

UnificationXref4432
type: UnificationXref
id: 5596267
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596267

UnificationXref4431
type: UnificationXref
id: 5596266
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596266

UnificationXref4434
type: UnificationXref
id: REACT_204238
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_204238.2

UnificationXref4433
type: UnificationXref
id: 5596269
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596269

UnificationXref4436
type: UnificationXref
id: REACT_209418
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_209418.2

SequenceSite159
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref4435
type: UnificationXref
id: 5597084
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597084

SequenceSite158
type: SequenceSite
position status: EQUAL
sequence position: 480

UnificationXref4438
type: UnificationXref
id: REACT_191581
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_191581.3

UnificationXref4437
type: UnificationXref
id: 5596761
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596761

UnificationXref4439
type: UnificationXref
id: PFI1610c
db: UniProt

SequenceSite160
type: SequenceSite
position status: EQUAL
sequence position: 732

SequenceSite167
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/15665109
type: PublicationXref
id: 15665109
author: Dirago, L
author: Mifsud, S
author: Hyland, C
author: Alexander, WS
author: Hilton, DJ
author: Carpinelli, MR
author: Nicola, NA
author: Metcalf, D
db: Pubmed
title: Anomalous megakaryocytopoiesis in mice with mutations in the c-Myb gene
source: Blood 105:3480-7
year: 2005

SequenceSite168
type: SequenceSite
position status: EQUAL
sequence position: 393

SequenceSite165
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite166
type: SequenceSite
position status: EQUAL
sequence position: 334

SequenceSite163
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite164
type: SequenceSite
position status: EQUAL
sequence position: 334

SequenceSite161
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite162
type: SequenceSite
position status: EQUAL
sequence position: 334

UnificationXref4443
type: UnificationXref
id: 5595707
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595707

UnificationXref4442
type: UnificationXref
id: 5595706
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595706

UnificationXref4441
type: UnificationXref
id: PF14_0417
db: UniProt

UnificationXref4440
type: UnificationXref
id: 5595704
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595704

UnificationXref4447
type: UnificationXref
id: 1250243
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=1250243

UnificationXref4446
type: UnificationXref
id: CHEBI:26523
db: ChEBI

SequenceSite169
type: SequenceSite
position status: EQUAL
sequence position: 17

UnificationXref4445
type: UnificationXref
id: REACT_245223
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_245223.1

UnificationXref4444
type: UnificationXref
id: 5595708
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595708

UnificationXref4449
type: UnificationXref
id: 5595903
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595903

UnificationXref4448
type: UnificationXref
id: REACT_76566
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_76566.1

SequenceSite170
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite171
type: SequenceSite
position status: EQUAL
sequence position: 480

SequenceSite176
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite177
type: SequenceSite
position status: EQUAL
sequence position: 480

SequenceSite178
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite179
type: SequenceSite
position status: EQUAL
sequence position: 558

SequenceSite172
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite173
type: SequenceSite
position status: EQUAL
sequence position: 480

SequenceSite174
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite175
type: SequenceSite
position status: EQUAL
sequence position: 480

UnificationXref4499
type: UnificationXref
id: 5596865
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596865

SequenceSite138
type: SequenceSite
position status: EQUAL
sequence position: 246

SequenceSite139
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite136
type: SequenceSite
position status: EQUAL
sequence position: 648

SequenceSite137
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref4495
type: UnificationXref
id: 428981
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=428981

PI3K events in ERBB2 signaling
type: Pathway
data source: Provenance1
pathway component: REACT 237994.1
evidence: Evidence792
xref: UnificationXref4620
xref: UnificationXref4619
pathway order: PathwayStep77
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4496
type: UnificationXref
id: REACT_20410
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_20410.2

UnificationXref4497
type: UnificationXref
id: 5596250
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596250

UnificationXref4498
type: UnificationXref
id: REACT_205539
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_205539.2

UnificationXref4492
type: UnificationXref
id: REACT_20105
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_20105.2

SequenceSite142
type: SequenceSite
position status: EQUAL
sequence position: 480

UnificationXref4491
type: UnificationXref
id: 428980
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=428980

SequenceSite141
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref4494
type: UnificationXref
id: REACT_3333
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3333.2

SequenceSite140
type: SequenceSite
position status: EQUAL
sequence position: 480

UnificationXref4493
type: UnificationXref
id: 140356
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=140356

SequenceSite146
type: SequenceSite
position status: EQUAL
sequence position: 420

SequenceSite145
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref4490
type: UnificationXref
id: REACT_193013
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_193013.3

SequenceSite144
type: SequenceSite
position status: EQUAL
sequence position: 483

SequenceSite143
type: SequenceSite
position status: EQUAL
sequence position: 2

http://identifiers.org/pubmed/224930
type: PublicationXref
id: 224930
author: Inoue, K
author: Yamasawa, K
author: Nishimukai, H
db: Pubmed
title: Purification and partial characterization of aldehyde dehydrogenase from human erythrocytes.
source: Biochim Biophys Acta 569:117-23
year: 1979

http://identifiers.org/pubmed/18436705
type: PublicationXref
id: 18436705
author: Scheuner, D
author: Kaufman, RJ
db: Pubmed
title: The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes
source: Endocr Rev 29:317-33
year: 2008

SequenceSite147
type: SequenceSite
position status: EQUAL
sequence position: 21

SequenceSite148
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite149
type: SequenceSite
position status: EQUAL
sequence position: 483

SequenceSite151
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite150
type: SequenceSite
position status: EQUAL
sequence position: 9

SequenceSite153
type: SequenceSite
position status: EQUAL
sequence position: 308

SequenceSite152
type: SequenceSite
position status: EQUAL
sequence position: 420

SequenceSite155
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite154
type: SequenceSite
position status: EQUAL
sequence position: 473

http://identifiers.org/pubmed/9296496
type: PublicationXref
id: 9296496
author: Simon, MI
author: Hu, YH
author: Toombs, CF
author: Offermanns, S
db: Pubmed
title: Defective platelet activation in G alpha(q)-deficient mice
source: Nature 389:183-6
year: 1997

SequenceSite157
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite156
type: SequenceSite
position status: EQUAL
sequence position: 480

L-glutamic acid removal
type: SequenceModificationVocabulary
xref: UnificationXref632

UnificationXref4473
type: UnificationXref
id: 5597036
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597036

http://identifiers.org/pubmed/10825291
type: PublicationXref
id: 10825291
author: Pepperkok, R
author: Paccaud, JP
author: Stephens, DJ
author: Lin-Marq, N
author: Pagano, A
db: Pubmed
title: COPI-coated ER-to-Golgi transport complexes segregate from COPII in close proximity to ER exit sites
source: J Cell Sci 113:2177-85
year: 2000

UnificationXref4474
type: UnificationXref
id: REACT_192669
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192669.3

UnificationXref4475
type: UnificationXref
id: PFE1390w
db: UniProt

SequenceSite118
type: SequenceSite
position status: EQUAL
sequence position: 840

UnificationXref4476
type: UnificationXref
id: 5596464
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596464

SequenceSite119
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref4477
type: UnificationXref
id: CHEBI:49537
db: ChEBI

SequenceSite116
type: SequenceSite
position status: EQUAL
sequence position: 856

UnificationXref4478
type: UnificationXref
id: 2395973
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2395973

SequenceSite117
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref4479
type: UnificationXref
id: REACT_148079
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_148079.2

SequenceSite114
type: SequenceSite
position status: EQUAL
sequence position: 837

SequenceSite115
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite124
type: SequenceSite
position status: EQUAL
sequence position: 350

Stoichiometry407
type: Stoichiometry
physical entity: Protein354
stoichiometric coefficient: 2.0

SequenceSite123
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry408
type: Stoichiometry
physical entity: SmallMolecule206
stoichiometric coefficient: 1.0

SequenceSite122
type: SequenceSite
position status: EQUAL
sequence position: 351

Stoichiometry405
type: Stoichiometry
physical entity: Protein352
stoichiometric coefficient: 2.0

SequenceSite121
type: SequenceSite
position status: EQUAL
sequence position: 1

Stoichiometry406
type: Stoichiometry
physical entity: Protein353
stoichiometric coefficient: 2.0

UnificationXref4470
type: UnificationXref
id: 5595713
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595713

SequenceSite120
type: SequenceSite
position status: EQUAL
sequence position: 155

MPS IIIB - Sanfilippo syndrome B
type: Pathway
data source: Provenance1
pathway component: REACT 250358.1
evidence: Evidence97
xref: UnificationXref590
xref: UnificationXref591
pathway order: PathwayStep92
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4472
type: UnificationXref
id: REACT_219530
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_219530.2

Stoichiometry409
type: Stoichiometry
physical entity: Protein355
stoichiometric coefficient: 1.0

UnificationXref4471
type: UnificationXref
id: 5595714
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595714

Stoichiometry400
type: Stoichiometry
physical entity: PhysicalEntity10
stoichiometric coefficient: 2.0

Stoichiometry403
type: Stoichiometry
physical entity: Protein351
stoichiometric coefficient: 2.0

Stoichiometry404
type: Stoichiometry
physical entity: Protein248
stoichiometric coefficient: 2.0

Stoichiometry401
type: Stoichiometry
physical entity: Protein347
stoichiometric coefficient: 2.0

Stoichiometry402
type: Stoichiometry
physical entity: SmallMolecule96
stoichiometric coefficient: 2.0

UnificationXref4486
type: UnificationXref
id: REACT_205071
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_205071.2

SequenceSite129
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref4487
type: UnificationXref
id: 5597112
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597112

UnificationXref4484
type: UnificationXref
id: 5596466
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596466

UnificationXref4485
type: UnificationXref
id: 5596467
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596467

SequenceSite125
type: SequenceSite
position status: EQUAL
sequence position: 771

SequenceSite126
type: SequenceSite
position status: EQUAL
sequence position: 783

UnificationXref4488
type: UnificationXref
id: REACT_193014
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_193014.3

SequenceSite127
type: SequenceSite
position status: EQUAL
sequence position: 1253

UnificationXref4489
type: UnificationXref
id: 5597113
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597113

SequenceSite128
type: SequenceSite
position status: EQUAL
sequence position: 472

Mismatch Repair
type: Pathway
data source: Provenance1
pathway component: REACT 241593.1
pathway component: REACT 255527.1
evidence: Evidence712
xref: UnificationXref4344
xref: UnificationXref4343
xref: RelationshipXref582
pathway order: PathwayStep695
pathway order: PathwayStep692
display name: MMR
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

SequenceSite133
type: SequenceSite
position status: EQUAL
sequence position: 259

SequenceSite132
type: SequenceSite
position status: EQUAL
sequence position: 149

SequenceSite135
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite134
type: SequenceSite
position status: EQUAL
sequence position: 621

UnificationXref4483
type: UnificationXref
id: 5596465
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596465

UnificationXref4482
type: UnificationXref
id: REACT_160853
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_160853.1

UnificationXref4481
type: UnificationXref
id: 3134845
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=3134845

SequenceSite131
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref4480
type: UnificationXref
id: CHEBI:47037
db: ChEBI

SequenceSite130
type: SequenceSite
position status: EQUAL
sequence position: 1290

http://identifiers.org/pubmed/6693436
type: PublicationXref
id: 6693436
author: Hu, SZ
author: Wang, TS
author: Korn, D
db: Pubmed
title: DNA primase from KB cells. Characterization of a primase activity tightly associated with immunoaffinity-purified DNA polymerase-alpha.
source: J Biol Chem 259:1854-65
year: 1984

UnificationXref2381
type: UnificationXref
id: REACT_5822
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5822.2

UnificationXref2382
type: UnificationXref
id: CHEBI:17256
db: ChEBI

http://identifiers.org/pubmed/17598937
type: PublicationXref
id: 17598937
author: Matijevi?, Tanja
author: Paveli?, Jasminka
author: Knezevi?, Jelena
db: Pubmed
title: Biological & physiological aspects of action of insulin-like growth factor peptide family
source: Indian J. Med. Res. 125:511-22
year: 2007

UnificationXref2380
type: UnificationXref
id: 83909
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=83909

http://identifiers.org/pubmed/20153287
type: PublicationXref
id: 20153287
author: Wallace, J C
author: Bailey, L M
author: Polyak, S W
db: Pubmed
title: Holocarboxylase synthetase: correlation of protein localisation with biological function
source: Arch. Biochem. Biophys. 496:45-52
year: 2010

http://identifiers.org/pubmed/9839448
type: PublicationXref
id: 9839448
author: Aureli, G
author: Federici, G
author: Petruzzelli, R
author: Ricci, G
author: Pastore, A
author: Di Ilio, C
author: Lo Bello, M
db: Pubmed
title: Purification and characterization of a novel alpha-class glutathione transferase from human liver
source: Int. J. Biochem. Cell Biol. 30:1235-43
year: 1998

UnificationXref3436
type: UnificationXref
id: 5593793
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593793

UnificationXref3437
type: UnificationXref
id: 5593794
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593794

UnificationXref3438
type: UnificationXref
id: 5593817
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593817

UnificationXref3439
type: UnificationXref
id: 5594377
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594377

SequenceSite1531
type: SequenceSite
position status: EQUAL
sequence position: 2136

SequenceSite1532
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite1530
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite1535
type: SequenceSite
position status: EQUAL
sequence position: 941

UnificationXref2386
type: UnificationXref
id: CHEBI:16134
db: ChEBI

SequenceSite1536
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2385
type: UnificationXref
id: 5593926
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593926

PublicationXref1173
type: PublicationXref
author: Page, C
author: Vermylen, J
author: Fuster, V
author: Gresele, P
title: Platelets in thrombotic and non-thrombotic disorders.
source: 435-437
year: 2002

SequenceSite1533
type: SequenceSite
position status: EQUAL
sequence position: 972

UnificationXref2384
type: UnificationXref
id: REACT_3734
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3734.2

UnificationXref3430
type: UnificationXref
id: 5593777
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593777

SequenceSite1534
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2383
type: UnificationXref
id: 83925
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=83925

UnificationXref3431
type: UnificationXref
id: PF13_0132
db: UniProt

SequenceSite1539
type: SequenceSite
position status: EQUAL
sequence position: 900

UnificationXref3432
type: UnificationXref
id: 5593758
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593758

UnificationXref2389
type: UnificationXref
id: CHEBI:17596
db: ChEBI

UnificationXref3433
type: UnificationXref
id: PFB0455w.1
db: UniProt

SequenceSite1537
type: SequenceSite
position status: EQUAL
sequence position: 968

UnificationXref2388
type: UnificationXref
id: REACT_3820
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3820.1

UnificationXref3434
type: UnificationXref
id: 5593791
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593791

SequenceSite1538
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2387
type: UnificationXref
id: 29382
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29382

UnificationXref3435
type: UnificationXref
id: PFB0455w.2
db: UniProt

UnificationXref2370
type: UnificationXref
id: REACT_242783
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_242783.1

UnificationXref2371
type: UnificationXref
id: 5594270
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594270

UnificationXref3427
type: UnificationXref
id: 5593805
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593805

UnificationXref3428
type: UnificationXref
id: 5593806
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593806

UnificationXref3425
type: UnificationXref
id: 5593803
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593803

UnificationXref3426
type: UnificationXref
id: PFC0200w.1
db: UniProt

SequenceSite1540
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite1541
type: SequenceSite
position status: EQUAL
sequence position: 1512

SequenceSite1542
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref3429
type: UnificationXref
id: PFI0190w
db: UniProt

SequenceSite1543
type: SequenceSite
position status: EQUAL
sequence position: 501

SequenceSite1544
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2373
type: UnificationXref
id: 5594267
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594267

SequenceSite1545
type: SequenceSite
position status: EQUAL
sequence position: 660

UnificationXref2372
type: UnificationXref
id: 5594269
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594269

UnificationXref3420
type: UnificationXref
id: PF10_0043
db: UniProt

SequenceSite1546
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref2375
type: UnificationXref
id: 5593912
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593912

SequenceSite1547
type: SequenceSite
position status: EQUAL
sequence position: 597

UnificationXref2374
type: UnificationXref
id: 5594268
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594268

SequenceSite1548
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2377
type: UnificationXref
id: 5596723
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596723

UnificationXref3423
type: UnificationXref
id: 5593756
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593756

SequenceSite1549
type: SequenceSite
position status: EQUAL
sequence position: 1176

UnificationXref2376
type: UnificationXref
id: REACT_204804
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_204804.2

UnificationXref3424
type: UnificationXref
id: PFC0200w.2
db: UniProt

UnificationXref2379
type: UnificationXref
id: CHEBI:16335
db: ChEBI

UnificationXref3421
type: UnificationXref
id: 5593738
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593738

Purine ribonucleoside monophosphate biosynthesis
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction211
pathway component: BiochemicalReaction213
pathway component: BiochemicalReaction212
pathway component: BiochemicalReaction215
pathway component: BiochemicalReaction214
evidence: Evidence394
xref: RelationshipXref380
xref: UnificationXref2377
xref: UnificationXref2378
pathway order: PathwayStep386
pathway order: PathwayStep390
pathway order: PathwayStep387
pathway order: PathwayStep388
pathway order: PathwayStep389
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref2378
type: UnificationXref
id: REACT_251054
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_251054.1

UnificationXref3422
type: UnificationXref
id: PF13_0171
db: UniProt

Signaling by GPCR
type: Pathway
data source: Provenance1
pathway component: REACT 250746.1
pathway component: REACT 253603.1
pathway component: REACT 230516.1
evidence: Evidence807
xref: UnificationXref4654
xref: UnificationXref4653
pathway order: PathwayStep780
pathway order: PathwayStep787
pathway order: PathwayStep786
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

SequenceSite1553
type: SequenceSite
position status: EQUAL
sequence position: 1262

SequenceSite1554
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite1551
type: SequenceSite
position status: EQUAL
sequence position: 775

SequenceSite1552
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/19783045
type: PublicationXref
id: 19783045
author: Kongsuphol, Patthara
author: Kunzelmann, Karl
author: Schreiber, Rainer
author: Warth, R
author: Tian, Yuemin
author: Ousingsawat, Jiraporn
author: Aldehni, Fadi
db: Pubmed
title: Bestrophin and TMEM16-Ca(2+) activated Cl(-) channels with different functions
source: Cell Calcium 46:233-41
year: 2009

UnificationXref3458
type: UnificationXref
id: PF07_0080
db: UniProt

SequenceSite1550
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref3459
type: UnificationXref
id: 5593597
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593597

PublicationXref1156
type: PublicationXref
author: Marks, F
author: Raab, I
title: The second messenger system of mouse epidermis. IV. Cyclic AMP and cyclic GMP phosphodiesterase.
source: Biochim. Biophys. Acta 334:368-377
year: 1974

UnificationXref3454
type: UnificationXref
id: PFC1020c
db: UniProt

http://identifiers.org/pubmed/3965505
type: PublicationXref
id: 3965505
author: Smith, PM
author: Schmaier, AH
author: Colman, RW
db: Pubmed
title: Platelet C1- inhibitor. A secreted alpha-granule protein.
source: J Clin Invest 75:242-50
year: 1985

UnificationXref3455
type: UnificationXref
id: 5593641
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593641

SequenceSite1559
type: SequenceSite
position status: EQUAL
sequence position: 748

UnificationXref3456
type: UnificationXref
id: PFE0810c
db: UniProt

http://identifiers.org/pubmed/3893466
type: PublicationXref
id: 3893466
author: Jornvall, H
db: Pubmed
title: Alcohol dehydrogenases, aldehyde dehydrogenases, and related enzymes
source: Alcohol 2:61-6
year: 1985

UnificationXref3457
type: UnificationXref
id: 5593605
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593605

SequenceSite1557
type: SequenceSite
position status: EQUAL
sequence position: 548

UnificationXref3450
type: UnificationXref
id: 5593690
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593690

SequenceSite1558
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref3451
type: UnificationXref
id: 5593693
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593693

SequenceSite1555
type: SequenceSite
position status: EQUAL
sequence position: 312

UnificationXref3452
type: UnificationXref
id: PF11_0447
db: UniProt

SequenceSite1556
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref3453
type: UnificationXref
id: 5593675
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593675

UnificationXref2390
type: UnificationXref
id: 83927
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=83927

UnificationXref2391
type: UnificationXref
id: REACT_3272
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3272.2

UnificationXref2392
type: UnificationXref
id: CHEBI:28997
db: ChEBI

UnificationXref2393
type: UnificationXref
id: 109331
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=109331

http://identifiers.org/pubmed/7890667
type: PublicationXref
id: 7890667
author: Liu, SM
author: Cheng, HF
author: Wong, LP
author: King, K
author: Jiang, MJ
author: Chen, CL
author: Lomasney, JW
db: Pubmed
title: Cloning and identification of amino acid residues of human phospholipase C delta 1 essential for catalysis
source: J Biol Chem 270:5495-505
year: 1995

UniProt:PFB0410c
type: ProteinReference
xref: UnificationXref1680
organism: http://identifiers.org/taxonomy/5833

SequenceSite1562
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite1563
type: SequenceSite
position status: EQUAL
sequence position: 509

SequenceSite1564
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite1565
type: SequenceSite
position status: EQUAL
sequence position: 514

UnificationXref3449
type: UnificationXref
id: 5593689
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593689

UniProt:PFF0700c
type: ProteinReference
xref: UnificationXref3401
organism: http://identifiers.org/taxonomy/5833

SequenceSite1560
type: SequenceSite
position status: EQUAL
sequence position: 55

UnificationXref3447
type: UnificationXref
id: PF14_0655
db: UniProt

http://identifiers.org/pubmed/8662720
type: PublicationXref
id: 8662720
author: Korenberg, J
author: Garrow, TA
author: Qi, H
author: Choi, YJ
author: Shane, B
author: Chen, L
db: Pubmed
title: Purification and properties of human cytosolic folylpoly-gamma-glutamate synthetase and organization, localization, and differential splicing of its gene
source: J Biol Chem 271:13077-87
year: 1996

SequenceSite1561
type: SequenceSite
position status: EQUAL
sequence position: 739

UnificationXref3448
type: UnificationXref
id: 5593688
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593688

UnificationXref2399
type: UnificationXref
id: REACT_194969
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_194969.3

UnificationXref3445
type: UnificationXref
id: MAL13P1.63
db: UniProt

UnificationXref2398
type: UnificationXref
id: 5593931
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593931

UnificationXref3446
type: UnificationXref
id: 5593692
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593692

UnificationXref3443
type: UnificationXref
id: PFL1170w
db: UniProt

UnificationXref3444
type: UnificationXref
id: 5594373
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594373

SequenceSite1566
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2395
type: UnificationXref
id: 5593927
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593927

UnificationXref3441
type: UnificationXref
id: REACT_236891
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_236891.1

SequenceSite1567
type: SequenceSite
position status: EQUAL
sequence position: 723

UnificationXref2394
type: UnificationXref
id: REACT_4959
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4959.2

UnificationXref3442
type: UnificationXref
id: 5594371
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594371

SequenceSite1568
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref2397
type: UnificationXref
id: 5593929
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593929

UniProt:PFE0160c
type: ProteinReference
xref: UnificationXref5396
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/14500886
type: PublicationXref
id: 14500886
author: Green, S
author: Warrington, JA
author: Davis, S
author: Wolfe, CL
author: Norcum, MT
db: Pubmed
title: Isolation and characterization of human nuclear and cytosolic multisynthetase complexes and the intracellular distribution of p43/EMAPII
source: Protein Sci 12:2282-90
year: 2003

SequenceSite1569
type: SequenceSite
position status: EQUAL
sequence position: 471

UnificationXref2396
type: UnificationXref
id: PF10_0289
db: UniProt

UnificationXref3440
type: UnificationXref
id: 5594378
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594378

http://identifiers.org/pubmed/12941691
type: PublicationXref
id: 12941691
author: Youle, RJ
author: Sharpe, JC
author: Gaume, B
author: Arnoult, D
author: Cecconi, F
author: Karbowski, M
db: Pubmed
title: Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization.
source: EMBO J 22:4385-99
year: 2003

http://identifiers.org/pubmed/1702903
type: PublicationXref
id: 1702903
author: Toyoshima, K
author: Kakiuchi, T
author: Yamanashi, Y
author: Mizuguchi, J
author: Yamamoto, T
db: Pubmed
title: Association of B cell antigen receptor with protein tyrosine kinase Lyn
source: Science 251:192-4
year: 1991

http://identifiers.org/pubmed/9294177
type: PublicationXref
id: 9294177
author: Genschel, J
author: Drummond, J T
author: Wolf, E
author: Modrich, P
db: Pubmed
title: DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair
source: Proc. Natl. Acad. Sci. U.S.A. 94:10144-9
year: 1997

SequenceSite1579
type: SequenceSite
position status: EQUAL
sequence position: 985

SequenceSite1578
type: SequenceSite
position status: EQUAL
sequence position: 24

SequenceSite1577
type: SequenceSite
position status: EQUAL
sequence position: 289

SequenceSite1572
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite1571
type: SequenceSite
position status: EQUAL
sequence position: 528

SequenceSite1570
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite1576
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite1575
type: SequenceSite
position status: EQUAL
sequence position: 289

SequenceSite1574
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite1573
type: SequenceSite
position status: EQUAL
sequence position: 1264

http://identifiers.org/pubmed/11604561
type: PublicationXref
id: 11604561
author: Cattaneo, M
author: Ruggeri, ZM
author: Savage, B
db: Pubmed
title: Mechanisms of platelet aggregation
source: Curr Opin Hematol 8:270-6
year: 2001

Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
type: Pathway
data source: Provenance1
pathway component: REACT 257730.1
pathway component: REACT 242172.1
evidence: Evidence862
xref: UnificationXref4974
xref: UnificationXref4973
pathway order: PathwayStep841
pathway order: PathwayStep839
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

SequenceSite1589
type: SequenceSite
position status: EQUAL
sequence position: 739

SequenceSite1588
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/16746585
type: PublicationXref
id: 16746585
author: Salvin, E
author: Johnson, WA
author: Krebs, HA
db: Pubmed
title: The formation of citric and alpha-ketoglutaric acids in the mammalian body
source: Biochem J 32:113-117
year: 1938

SequenceSite1581
type: SequenceSite
position status: EQUAL
sequence position: 477

SequenceSite1580
type: SequenceSite
position status: EQUAL
sequence position: 15

SequenceSite1583
type: SequenceSite
position status: EQUAL
sequence position: 645

SequenceSite1582
type: SequenceSite
position status: EQUAL
sequence position: 48

SequenceSite1585
type: SequenceSite
position status: EQUAL
sequence position: 523

SequenceSite1584
type: SequenceSite
position status: EQUAL
sequence position: 42

http://identifiers.org/pubmed/19489725
type: PublicationXref
id: 19489725
author: Joazeiro, Claudio A
author: Deshaies, RJ
db: Pubmed
title: RING domain E3 ubiquitin ligases
source: Annu Rev Biochem 78:399-434
year: 2009

GAB1 signalosome
type: Pathway
data source: Provenance1
pathway component: REACT 237994.1
evidence: Evidence79
xref: UnificationXref515
xref: UnificationXref514
pathway order: PathwayStep77
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

SequenceSite1587
type: SequenceSite
position status: EQUAL
sequence position: 775

SequenceSite1586
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite1590
type: SequenceSite
position status: EQUAL
sequence position: 34

http://identifiers.org/pubmed/8618861
type: PublicationXref
id: 8618861
author: Nevins, JR
author: DeGregori, J
author: Ohtani, K
db: Pubmed
title: Regulation of the cyclin E gene by transcription factor E2F1
source: Proc Natl Acad Sci U S A 92:12146-50
year: 1995

UnificationXref200
type: UnificationXref
id: 5596981
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596981

UnificationXref201
type: UnificationXref
id: REACT_248122
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_248122.1

UnificationXref3411
type: UnificationXref
id: 5593799
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593799

UnificationXref3410
type: UnificationXref
id: PF13_0346
db: UniProt

UnificationXref3413
type: UnificationXref
id: 5593773
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593773

UnificationXref3412
type: UnificationXref
id: PF10_0187
db: UniProt

SequenceSite1599
type: SequenceSite
position status: EQUAL
sequence position: 518

SequenceSite1598
type: SequenceSite
position status: EQUAL
sequence position: 35

UnificationXref3419
type: UnificationXref
id: 5593775
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593775

SequenceSite1597
type: SequenceSite
position status: EQUAL
sequence position: 475

UnificationXref3418
type: UnificationXref
id: PFE0185c
db: UniProt

SequenceSite1596
type: SequenceSite
position status: EQUAL
sequence position: 30

SequenceSite1595
type: SequenceSite
position status: EQUAL
sequence position: 593

SequenceSite1594
type: SequenceSite
position status: EQUAL
sequence position: 30

UnificationXref3415
type: UnificationXref
id: 5593736
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593736

SequenceSite1593
type: SequenceSite
position status: EQUAL
sequence position: 597

UnificationXref3414
type: UnificationXref
id: PF08_0075
db: UniProt

SequenceSite1592
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref3417
type: UnificationXref
id: 5593798
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593798

SequenceSite1591
type: SequenceSite
position status: EQUAL
sequence position: 506

UnificationXref3416
type: UnificationXref
id: PFE0350c
db: UniProt

Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
type: Pathway
data source: Provenance1
pathway component: REACT 249357.1
evidence: Evidence741
xref: UnificationXref4456
xref: UnificationXref4455
xref: RelationshipXref596
pathway order: PathwayStep722
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

Pyruvate
type: SmallMoleculeReference
name: Pyruvic acid
name: Pyroracemic acid
name: 2-Oxopropanoate
name: 2-Oxopropanoic acid
name: Pyruvate [ChEBI:32816]
xref: UnificationXref735

UnificationXref3402
type: UnificationXref
id: 5593750
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593750

UnificationXref3401
type: UnificationXref
id: PFF0700c
db: UniProt

UnificationXref3400
type: UnificationXref
id: 5593732
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593732

http://identifiers.org/pubmed/11481335
type: PublicationXref
id: 11481335
author: Lardizabal, KD
author: Cases, S
author: Tow, B
author: Zhou, P
author: Farese, RV
author: Voelker, T
author: Yen, E
author: Stone, SJ
db: Pubmed
title: Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members
source: J Biol Chem 276:38870-6
year: 2001

UnificationXref3409
type: UnificationXref
id: 5593770
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593770

UnificationXref3408
type: UnificationXref
id: 5593796
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593796

UnificationXref3407
type: UnificationXref
id: PFF0573c
db: UniProt

UnificationXref3406
type: UnificationXref
id: 5593734
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593734

UnificationXref3405
type: UnificationXref
id: PFE0850c
db: UniProt

UnificationXref3404
type: UnificationXref
id: 5593771
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593771

UnificationXref3403
type: UnificationXref
id: PF10_0272
db: UniProt

UnificationXref2304
type: UnificationXref
id: 5593547
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593547

UnificationXref2303
type: UnificationXref
id: 5593504
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593504

UnificationXref2306
type: UnificationXref
id: CHEBI:15741
db: ChEBI

UnificationXref2305
type: UnificationXref
id: REACT_247113
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_247113.1

UnificationXref2308
type: UnificationXref
id: REACT_2775
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2775.2

UnificationXref2307
type: UnificationXref
id: 113536
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113536

UnificationXref2309
type: UnificationXref
id: PF14_0295
db: UniProt

UnificationXref215
type: UnificationXref
id: REACT_7132
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_7132.1

UnificationXref216
type: UnificationXref
id: 741440
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=741440

UnificationXref213
type: UnificationXref
id: CHEBI:17980
db: ChEBI

UnificationXref214
type: UnificationXref
id: 158471
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=158471

UnificationXref219
type: UnificationXref
id: 5595692
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595692

UnificationXref2300
type: UnificationXref
id: 29824
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29824

UnificationXref217
type: UnificationXref
id: REACT_22655
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_22655.1

UnificationXref2302
type: UnificationXref
id: 5593503
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593503

UnificationXref218
type: UnificationXref
id: PF11_0141
db: UniProt

UnificationXref2301
type: UnificationXref
id: REACT_3209
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3209.3

UnificationXref223
type: UnificationXref
id: REACT_240740
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_240740.1

UnificationXref222
type: UnificationXref
id: 5595696
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595696

UnificationXref221
type: UnificationXref
id: 5595694
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595694

http://identifiers.org/pubmed/11051212
type: PublicationXref
id: 11051212
author: Szkopinska, A
db: Pubmed
title: Ubiquinone. Biosynthesis of quinone ring and its isoprenoid side chain. Intracellular localization
source: Acta Biochim Pol 47:469-80
year: 2000

UnificationXref220
type: UnificationXref
id: 5595693
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595693

Stoichiometry398
type: Stoichiometry
physical entity: Protein346
stoichiometric coefficient: 2.0

Stoichiometry397
type: Stoichiometry
physical entity: SmallMolecule484
stoichiometric coefficient: 2.0

http://identifiers.org/pubmed/8617750
type: PublicationXref
id: 8617750
author: Green, JM
author: Cohen, BD
author: Fell, HP
author: Foy, L
db: Pubmed
title: HER4-mediated biological and biochemical properties in NIH 3T3 cells. Evidence for HER1-HER4 heterodimers
source: J Biol Chem 271:4813-8
year: 1996

Stoichiometry399
type: Stoichiometry
physical entity: SmallMolecule313
stoichiometric coefficient: 2.0

UnificationXref202
type: UnificationXref
id: CHEBI:15351
db: ChEBI

UnificationXref203
type: UnificationXref
id: 76183
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=76183

http://identifiers.org/pubmed/18043707
type: PublicationXref
id: 18043707
author: Hamm, HE
author: Oldham, WM
db: Pubmed
title: Heterotrimeric G protein activation by G-protein-coupled receptors
source: Nat Rev Mol Cell Biol 9:60-71
year: 2008

UnificationXref204
type: UnificationXref
id: REACT_2630
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2630.2

UnificationXref205
type: UnificationXref
id: GO:0005796
db: GENE ONTOLOGY

UnificationXref206
type: UnificationXref
id: 727753
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=727753

UnificationXref207
type: UnificationXref
id: REACT_23184
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_23184.2

UnificationXref208
type: UnificationXref
id: GO:0000139
db: GENE ONTOLOGY

UnificationXref209
type: UnificationXref
id: PF10_0360
db: UniProt

UnificationXref210
type: UnificationXref
id: 5595686
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595686

UnificationXref212
type: UnificationXref
id: REACT_218026
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_218026.2

UnificationXref211
type: UnificationXref
id: 5595688
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595688

http://identifiers.org/pubmed/16970545
type: PublicationXref
id: 16970545
author: Penning, Trevor M
author: Jin, Yi
db: Pubmed
title: Aldo-keto reductases and bioactivation/detoxication
source: Annu. Rev. Pharmacol. Toxicol. 47:263-92
year: 2007

UnificationXref2329
type: UnificationXref
id: 29586
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29586

Stoichiometry380
type: Stoichiometry
physical entity: SmallMolecule24
stoichiometric coefficient: 8.0

Stoichiometry381
type: Stoichiometry
physical entity: Protein343
stoichiometric coefficient: 8.0

UnificationXref2326
type: UnificationXref
id: 111409
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=111409

Stoichiometry382
type: Stoichiometry
physical entity: SmallMolecule24
stoichiometric coefficient: 4.0

UnificationXref2325
type: UnificationXref
id: CHEBI:18406
db: ChEBI

Stoichiometry383
type: Stoichiometry
physical entity: SmallMolecule471
stoichiometric coefficient: 4.0

UnificationXref2328
type: UnificationXref
id: CHEBI:37154
db: ChEBI

Stoichiometry384
type: Stoichiometry
physical entity: Protein343
stoichiometric coefficient: 8.0

UnificationXref2327
type: UnificationXref
id: REACT_2302
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2302.2

Stoichiometry385
type: Stoichiometry
physical entity: SmallMolecule24
stoichiometric coefficient: 4.0

UnificationXref2322
type: UnificationXref
id: CHEBI:18319
db: ChEBI

UnificationXref2321
type: UnificationXref
id: REACT_191643
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_191643.3

UnificationXref239
type: UnificationXref
id: 109276
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=109276

UnificationXref2324
type: UnificationXref
id: REACT_3661
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3661.2

UnificationXref2323
type: UnificationXref
id: 111399
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=111399

UnificationXref237
type: UnificationXref
id: 5596685
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596685

UnificationXref238
type: UnificationXref
id: REACT_238157
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_238157.1

UnificationXref235
type: UnificationXref
id: 5597016
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597016

UnificationXref2320
type: UnificationXref
id: 5596693
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596693

UnificationXref236
type: UnificationXref
id: REACT_192660
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192660.3

UnificationXref245
type: UnificationXref
id: 5595416
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595416

UnificationXref244
type: UnificationXref
id: 5595415
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595415

UnificationXref243
type: UnificationXref
id: 5595453
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595453

UniProt:PFL0335c
type: ProteinReference
xref: UnificationXref4704
organism: http://identifiers.org/taxonomy/5833

UnificationXref242
type: UnificationXref
id: 5595452
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595452

UnificationXref241
type: UnificationXref
id: PF11_0338
db: UniProt

UnificationXref240
type: UnificationXref
id: REACT_3225
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3225.1

http://identifiers.org/pubmed/9551553
type: PublicationXref
id: 9551553
author: McKinstry, W J
author: Rossjohn, J
author: Board, P G
author: Chelvanayagam, G
author: Parker, M W
author: Verger, D
author: Flanagan, J
author: Tan, K L
author: Oakley, A J
db: Pubmed
title: Human theta class glutathione transferase: the crystal structure reveals a sulfate-binding pocket within a buried active site
source: Structure 6:309-22
year: 1998

Stoichiometry376
type: Stoichiometry
physical entity: AHCY:NAD+ (name copied from entity in Homo sapiens)
stoichiometric coefficient: 4.0

Stoichiometry375
type: Stoichiometry
physical entity: SmallMolecule81
stoichiometric coefficient: 1.0

Stoichiometry378
type: Stoichiometry
physical entity: Protein342
stoichiometric coefficient: 2.0

Stoichiometry377
type: Stoichiometry
physical entity: Protein341
stoichiometric coefficient: 2.0

Stoichiometry379
type: Stoichiometry
physical entity: SmallMolecule471
stoichiometric coefficient: 4.0

Stoichiometry391
type: Stoichiometry
physical entity: SmallMolecule475
stoichiometric coefficient: 1.0

Stoichiometry392
type: Stoichiometry
physical entity: SmallMolecule122
stoichiometric coefficient: 4.0

UnificationXref2319
type: UnificationXref
id: REACT_245515
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_245515.1

UnificationXref2318
type: UnificationXref
id: 5596692
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596692

Stoichiometry390
type: Stoichiometry
physical entity: Protein344
stoichiometric coefficient: 1.0

UnificationXref2317
type: UnificationXref
id: REACT_255130
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_255130.1

Stoichiometry395
type: Stoichiometry
physical entity: SmallMolecule481
stoichiometric coefficient: 2.0

http://identifiers.org/pubmed/5940
type: PublicationXref
id: 5940
author: Povey, S
author: Wilson, Jr, DE
author: Harris, H
db: Pubmed
title: Adenylate kinases in man: evidence for a third locus
source: Ann Hum Genet 39:305-313
year: 1976

UnificationXref2316
type: UnificationXref
id: 5596699
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596699

Stoichiometry396
type: Stoichiometry
physical entity: SmallMolecule483
stoichiometric coefficient: 2.0

UnificationXref2315
type: UnificationXref
id: REACT_87261
db: Reactome
id version: 4
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_87261.4

Stoichiometry393
type: Stoichiometry
physical entity: Protein345
stoichiometric coefficient: 2.0

UnificationXref2314
type: UnificationXref
id: 5593495
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593495

Stoichiometry394
type: Stoichiometry
physical entity: SmallMolecule122
stoichiometric coefficient: 4.0

UnificationXref228
type: UnificationXref
id: REACT_22654
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_22654.2

UnificationXref2313
type: UnificationXref
id: 5593493
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593493

UnificationXref229
type: UnificationXref
id: PFB0535w
db: UniProt

UnificationXref2312
type: UnificationXref
id: 5593490
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593490

UnificationXref2311
type: UnificationXref
id: PF11_0097
db: UniProt

Metabolism of RNA
type: Pathway
data source: Provenance1
pathway component: REACT 239368.1
evidence: Evidence646
xref: RelationshipXref561
xref: UnificationXref4056
xref: UnificationXref4057
pathway order: PathwayStep630
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref2310
type: UnificationXref
id: 5593492
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593492

UnificationXref224
type: UnificationXref
id: CHEBI:17009
db: ChEBI

UnificationXref225
type: UnificationXref
id: 742368
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=742368

UnificationXref226
type: UnificationXref
id: REACT_23055
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_23055.2

UnificationXref227
type: UnificationXref
id: 205683
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=205683

UnificationXref232
type: UnificationXref
id: REACT_205646
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_205646.2

UnificationXref231
type: UnificationXref
id: 5595700
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595700

UnificationXref234
type: UnificationXref
id: REACT_192668
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192668.3

UnificationXref233
type: UnificationXref
id: 5597032
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597032

UnificationXref230
type: UnificationXref
id: 5595698
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595698

Stoichiometry389
type: Stoichiometry
physical entity: SmallMolecule354
stoichiometric coefficient: 4.0

Stoichiometry388
type: Stoichiometry
physical entity: SmallMolecule473
stoichiometric coefficient: 4.0

Stoichiometry387
type: Stoichiometry
physical entity: SmallMolecule8
stoichiometric coefficient: 2.0

Stoichiometry386
type: Stoichiometry
physical entity: SmallMolecule472
stoichiometric coefficient: 2.0

http://identifiers.org/pubmed/17556371
type: PublicationXref
id: 17556371
author: Ikonomov, OC
author: Sbrissa, D
author: Gruenberg, J
author: Shisheva, A
author: Fu, Z
author: Ijuin, T
author: Takenawa, T
db: Pubmed
title: Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex
source: J Biol Chem 282:23878-91
year: 2007

UnificationXref3475
type: UnificationXref
id: 5593599
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593599

UnificationXref259
type: UnificationXref
id: REACT_3756
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3756.1

UnificationXref2340
type: UnificationXref
id: 111584
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=111584

UnificationXref3474
type: UnificationXref
id: PFC0775w
db: UniProt

UnificationXref258
type: UnificationXref
id: 76116
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=76116

UnificationXref2341
type: UnificationXref
id: REACT_3823
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3823.2

UnificationXref3473
type: UnificationXref
id: 5593607
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593607

UnificationXref257
type: UnificationXref
id: REACT_9588
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_9588.2

UnificationXref2342
type: UnificationXref
id: PFI1020c
db: UniProt

UnificationXref3472
type: UnificationXref
id: MAL13P1.92
db: UniProt

UnificationXref2343
type: UnificationXref
id: 5593902
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593902

UnificationXref3479
type: UnificationXref
id: 5593649
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593649

UnificationXref2344
type: UnificationXref
id: 5593903
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593903

UnificationXref3478
type: UnificationXref
id: PF13_0014
db: UniProt

UnificationXref2345
type: UnificationXref
id: 5593905
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593905

UnificationXref3477
type: UnificationXref
id: 5593625
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593625

UnificationXref2346
type: UnificationXref
id: REACT_238434
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_238434.1

UnificationXref3476
type: UnificationXref
id: PFC0290w
db: UniProt

UnificationXref2347
type: UnificationXref
id: 5593906
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593906

UnificationXref2348
type: UnificationXref
id: CHEBI:17345
db: ChEBI

UnificationXref2349
type: UnificationXref
id: 113578
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113578

http://identifiers.org/pubmed/12084581
type: PublicationXref
id: 12084581
author: Imai, M
author: Morinaga, T
author: Ishibashi, K
author: Sasaki, S
author: Kuwahara, M
db: Pubmed
title: Cloning and identification of a new member of water channel (AQP10) as an aquaglyceroporin
source: Biochim Biophys Acta 1576:335-40
year: 2002

UnificationXref262
type: UnificationXref
id: 5595598
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595598

UnificationXref263
type: UnificationXref
id: REACT_204391
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_204391.2

UnificationXref260
type: UnificationXref
id: 5595596
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595596

UnificationXref261
type: UnificationXref
id: REACT_222705
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_222705.2

UnificationXref266
type: UnificationXref
id: REACT_21102
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_21102.1

UnificationXref3470
type: UnificationXref
id: PF11_0065
db: UniProt

UnificationXref267
type: UnificationXref
id: 29514
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29514

UnificationXref3471
type: UnificationXref
id: 5593643
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593643

UnificationXref264
type: UnificationXref
id: CHEBI:16199
db: ChEBI

UnificationXref265
type: UnificationXref
id: 432019
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=432019

SequenceSite1503
type: SequenceSite
position status: EQUAL
sequence position: 221

UnificationXref247
type: UnificationXref
id: 5595412
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595412

UnificationXref2330
type: UnificationXref
id: REACT_5412
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5412.3

UnificationXref3462
type: UnificationXref
id: PFB0830w
db: UniProt

SequenceSite1502
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref246
type: UnificationXref
id: 5595411
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595411

UnificationXref2331
type: UnificationXref
id: PFB0295w
db: UniProt

UnificationXref3461
type: UnificationXref
id: 5593603
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593603

SequenceSite1501
type: SequenceSite
position status: EQUAL
sequence position: 221

UnificationXref249
type: UnificationXref
id: 5595591
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595591

UnificationXref3464
type: UnificationXref
id: PF07_0088
db: UniProt

SequenceSite1500
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref248
type: UnificationXref
id: 5595590
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595590

UnificationXref3463
type: UnificationXref
id: 5593629
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593629

SequenceSite1507
type: SequenceSite
position status: EQUAL
sequence position: 1217

UnificationXref2334
type: UnificationXref
id: 5593911
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593911

UnificationXref3466
type: UnificationXref
id: PF08_0076
db: UniProt

SequenceSite1506
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2335
type: UnificationXref
id: REACT_215399
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_215399.2

UnificationXref3465
type: UnificationXref
id: 5593645
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593645

SequenceSite1505
type: SequenceSite
position status: EQUAL
sequence position: 248

UnificationXref2332
type: UnificationXref
id: 5593908
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593908

UnificationXref3468
type: UnificationXref
id: PFE0975c
db: UniProt

SequenceSite1504
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref2333
type: UnificationXref
id: 5593909
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593909

UnificationXref3467
type: UnificationXref
id: 5593609
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593609

UnificationXref2338
type: UnificationXref
id: REACT_2342
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2342.1

UnificationXref2339
type: UnificationXref
id: CHEBI:15652
db: ChEBI

UnificationXref3469
type: UnificationXref
id: 5593627
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593627

UnificationXref2336
type: UnificationXref
id: CHEBI:17202
db: ChEBI

UnificationXref2337
type: UnificationXref
id: 29602
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29602

http://identifiers.org/pubmed/5666113
type: PublicationXref
id: 5666113
author: Luzzatto, L
author: Afolayan, A
db: Pubmed
title: Enzymic properties of different types of human erythrocyte glucose-6-phosphate dehydrogenase, with characterization of two new genetic variants
source: J Clin Invest 47:1833-42
year: 1968

http://identifiers.org/pubmed/17186029
type: PublicationXref
id: 17186029
author: Mariathasan, S
author: Monack, DM
db: Pubmed
title: Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation
source: Nat Rev Immunol 7:31-40
year: 2007

UnificationXref250
type: UnificationXref
id: 5595592
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595592

UnificationXref251
type: UnificationXref
id: 5595594
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595594

UnificationXref252
type: UnificationXref
id: REACT_204169
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_204169.2

UnificationXref253
type: UnificationXref
id: 5595597
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595597

UnificationXref254
type: UnificationXref
id: REACT_208766
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_208766.2

UnificationXref255
type: UnificationXref
id: CHEBI:17754
db: ChEBI

UnificationXref256
type: UnificationXref
id: 192438
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=192438

UnificationXref3460
type: UnificationXref
id: PF13_0316
db: UniProt

SequenceSite1516
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2365
type: UnificationXref
id: 5594261
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594261

SequenceSite1515
type: SequenceSite
position status: EQUAL
sequence position: 1304

UnificationXref2366
type: UnificationXref
id: 5594262
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594262

SequenceSite1518
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2367
type: UnificationXref
id: 5594263
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594263

UnificationXref3499
type: UnificationXref
id: 5593635
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593635

SequenceSite1517
type: SequenceSite
position status: EQUAL
sequence position: 125

UnificationXref2368
type: UnificationXref
id: 5594264
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594264

UnificationXref3498
type: UnificationXref
id: MAL7P1.300
db: UniProt

SequenceSite1512
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref2361
type: UnificationXref
id: PF13_0287
db: UniProt

UnificationXref3497
type: UnificationXref
id: 5593617
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593617

SequenceSite1511
type: SequenceSite
position status: EQUAL
sequence position: 86

UnificationXref2362
type: UnificationXref
id: 5594258
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594258

UnificationXref3496
type: UnificationXref
id: PFC0735w
db: UniProt

SequenceSite1514
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2363
type: UnificationXref
id: 5594259
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594259

UnificationXref3495
type: UnificationXref
id: 5593651
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593651

SequenceSite1513
type: SequenceSite
position status: EQUAL
sequence position: 424

UnificationXref279
type: UnificationXref
id: REACT_212175
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_212175.2

UnificationXref2364
type: UnificationXref
id: 5594260
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594260

UnificationXref3494
type: UnificationXref
id: PF14_0083
db: UniProt

SequenceSite1510
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2369
type: UnificationXref
id: 5594266
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594266

http://identifiers.org/pubmed/11331907
type: PublicationXref
id: 11331907
author: Irvine, RF
author: Schell, MJ
db: Pubmed
title: Back in the water: the return of the inositol phosphates
source: Nat Rev Mol Cell Biol 2:327-38
year: 2001

UnificationXref280
type: UnificationXref
id: 5595418
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595418

UnificationXref281
type: UnificationXref
id: REACT_225650
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_225650.2

UnificationXref288
type: UnificationXref
id: 74722
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=74722

UnificationXref3492
type: UnificationXref
id: PFD1055w
db: UniProt

UnificationXref289
type: UnificationXref
id: REACT_5598
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5598.2

UnificationXref3493
type: UnificationXref
id: 5593615
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593615

UnificationXref286
type: UnificationXref
id: 5596988
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596988

UnificationXref2360
type: UnificationXref
id: REACT_4014
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4014.1

UnificationXref3490
type: UnificationXref
id: PFB0885w
db: UniProt

UnificationXref287
type: UnificationXref
id: REACT_213254
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_213254.2

UnificationXref3491
type: UnificationXref
id: 5593639
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593639

SequenceSite1508
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref284
type: UnificationXref
id: 5596987
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596987

SequenceSite1509
type: SequenceSite
position status: EQUAL
sequence position: 895

UnificationXref285
type: UnificationXref
id: REACT_214411
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_214411.2

UnificationXref282
type: UnificationXref
id: 5595414
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595414

UnificationXref283
type: UnificationXref
id: REACT_221758
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_221758.2

SequenceSite1529
type: SequenceSite
position status: EQUAL
sequence position: 142

UnificationXref2356
type: UnificationXref
id: 35141
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=35141

UnificationXref3488
type: UnificationXref
id: PF11_0272
db: UniProt

SequenceSite1528
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2357
type: UnificationXref
id: REACT_5442
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5442.2

UnificationXref3487
type: UnificationXref
id: 5593601
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593601

http://identifiers.org/pubmed/21413788
type: PublicationXref
id: 21413788
author: Dunaway-Mariano, Debra
author: Wu, Rui
author: Garland, Megan
author: Allen, Karen N
db: Pubmed
title: Homo sapiens dullard protein phosphatase shows a preference for the insulin-dependent phosphorylation site of lipin1
source: Biochemistry 50:3045-7
year: 2011

SequenceSite1527
type: SequenceSite
position status: EQUAL
sequence position: 128

UnificationXref2354
type: UnificationXref
id: REACT_254821
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_254821.1

SequenceSite1526
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref2355
type: UnificationXref
id: CHEBI:15919
db: ChEBI

UnificationXref3489
type: UnificationXref
id: 5593613
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593613

SequenceSite1525
type: SequenceSite
position status: EQUAL
sequence position: 2335

UnificationXref269
type: UnificationXref
id: 5595599
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595599

UnificationXref2352
type: UnificationXref
id: 5593898
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593898

UnificationXref3484
type: UnificationXref
id: PF10_0038
db: UniProt

SequenceSite1524
type: SequenceSite
position status: EQUAL
sequence position: 2

UnificationXref268
type: UnificationXref
id: REACT_2669
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2669.1

UnificationXref2353
type: UnificationXref
id: 5593900
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593900

UnificationXref3483
type: UnificationXref
id: 5593647
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593647

SequenceSite1523
type: SequenceSite
position status: EQUAL
sequence position: 820

UnificationXref2350
type: UnificationXref
id: REACT_2761
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2761.1

UnificationXref3486
type: UnificationXref
id: PFC0295c
db: UniProt

SequenceSite1522
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2351
type: UnificationXref
id: PF10_0123
db: UniProt

UnificationXref3485
type: UnificationXref
id: 5593621
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593621

SequenceSite1521
type: SequenceSite
position status: EQUAL
sequence position: 95

SequenceSite1520
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref2358
type: UnificationXref
id: CHEBI:17552
db: ChEBI

UnificationXref2359
type: UnificationXref
id: 29420
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29420

UnificationXref270
type: UnificationXref
id: 5595602
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595602

UnificationXref275
type: UnificationXref
id: REACT_209225
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_209225.2

UnificationXref276
type: UnificationXref
id: 5595455
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595455

UnificationXref3480
type: UnificationXref
id: PF11_0454
db: UniProt

UnificationXref277
type: UnificationXref
id: REACT_224077
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_224077.2

UnificationXref3481
type: UnificationXref
id: 5593623
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593623

UnificationXref278
type: UnificationXref
id: 5596998
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596998

UnificationXref3482
type: UnificationXref
id: PF13_0228
db: UniProt

UnificationXref271
type: UnificationXref
id: REACT_204246
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_204246.2

UnificationXref272
type: UnificationXref
id: 5595601
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595601

SequenceSite1519
type: SequenceSite
position status: EQUAL
sequence position: 357

UnificationXref273
type: UnificationXref
id: REACT_202225
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_202225.2

UnificationXref274
type: UnificationXref
id: 5597008
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597008

UnificationXref179
type: UnificationXref
id: REACT_254094
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_254094.1

Stoichiometry329
type: Stoichiometry
physical entity: SmallMolecule11
stoichiometric coefficient: 2.0

UnificationXref178
type: UnificationXref
id: 5596989
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596989

Stoichiometry328
type: Stoichiometry
physical entity: Protein303
stoichiometric coefficient: 2.0

UnificationXref177
type: UnificationXref
id: REACT_245454
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_245454.1

UnificationXref176
type: UnificationXref
id: 5596994
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596994

UnificationXref5680
type: UnificationXref
id: REACT_243935
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_243935.1

UnificationXref175
type: UnificationXref
id: REACT_241761
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_241761.1

UnificationXref174
type: UnificationXref
id: 5596993
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596993

UnificationXref5682
type: UnificationXref
id: REACT_17942
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17942.1

UnificationXref173
type: UnificationXref
id: REACT_229575
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_229575.1

UnificationXref5681
type: UnificationXref
id: 379747
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379747

UnificationXref172
type: UnificationXref
id: 5595444
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595444

UnificationXref171
type: UnificationXref
id: 5595442
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595442

Stoichiometry321
type: Stoichiometry
physical entity: Protein300
stoichiometric coefficient: 4.0

UnificationXref170
type: UnificationXref
id: GO:0030667
db: GENE ONTOLOGY

Stoichiometry320
type: Stoichiometry
physical entity: SmallMolecule96
stoichiometric coefficient: 8.0

Stoichiometry323
type: Stoichiometry
physical entity: SmallMolecule11
stoichiometric coefficient: 2.0

Stoichiometry322
type: Stoichiometry
physical entity: SmallMolecule7
stoichiometric coefficient: 2.0

Stoichiometry325
type: Stoichiometry
physical entity: SmallMolecule371
stoichiometric coefficient: 1.0

Stoichiometry324
type: Stoichiometry
physical entity: Protein301
stoichiometric coefficient: 6.0

Stoichiometry327
type: Stoichiometry
physical entity: SmallMolecule96
stoichiometric coefficient: 2.0

Stoichiometry326
type: Stoichiometry
physical entity: Protein302
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/8188258
type: PublicationXref
id: 8188258
author: Hameister, H
author: Schray, B
author: Hu, B
author: Knippers, R
author: Eberhard, D
author: Baack, M
author: Kaiser, E
author: Becher, S
db: Pubmed
title: The human EPRS locus (formerly the QARS locus): a gene encoding a class I and a class II aminoacyl-tRNA synthetase
source: Genomics 19:280-90
year: 1994

Stoichiometry330
type: Stoichiometry
physical entity: SmallMolecule11
stoichiometric coefficient: 2.0

UnificationXref5683
type: UnificationXref
id: 29444
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29444

UnificationXref5684
type: UnificationXref
id: REACT_3737
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3737.2

UnificationXref5685
type: UnificationXref
id: 379795
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379795

UnificationXref5686
type: UnificationXref
id: REACT_16107
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_16107.1

UnificationXref5687
type: UnificationXref
id: 5595173
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595173

UnificationXref5688
type: UnificationXref
id: 5595174
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595174

UnificationXref5689
type: UnificationXref
id: 5595176
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595176

UnificationXref169
type: UnificationXref
id: REACT_16092
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_16092.3

Metabolism of folate and pterines
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction96
pathway component: BiochemicalReaction93
pathway component: BiochemicalReaction92
pathway component: BiochemicalReaction95
pathway component: BiochemicalReaction94
evidence: Evidence187
xref: RelationshipXref161
xref: UnificationXref1119
xref: UnificationXref1120
pathway order: PathwayStep185
pathway order: PathwayStep181
pathway order: PathwayStep182
pathway order: PathwayStep183
pathway order: PathwayStep184
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref188
type: UnificationXref
id: REACT_22773
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_22773.2

UnificationXref187
type: UnificationXref
id: 597613
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=597613

Stoichiometry319
type: Stoichiometry
physical entity: Protein299
stoichiometric coefficient: 1.0

Stoichiometry318
type: Stoichiometry
physical entity: SmallMolecule24
stoichiometric coefficient: 1.0

UnificationXref189
type: UnificationXref
id: 597625
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=597625

Stoichiometry317
type: Stoichiometry
physical entity: Protein298
stoichiometric coefficient: 4.0

UnificationXref5693
type: UnificationXref
id: 379705
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379705

UnificationXref184
type: UnificationXref
id: 597598
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=597598

UnificationXref5692
type: UnificationXref
id: REACT_16039
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_16039.1

UnificationXref183
type: UnificationXref
id: CHEBI:28593
db: ChEBI

UnificationXref5691
type: UnificationXref
id: 379741
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379741

UnificationXref186
type: UnificationXref
id: 5595670
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595670

UnificationXref5690
type: UnificationXref
id: REACT_245730
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_245730.1

UnificationXref185
type: UnificationXref
id: REACT_23056
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_23056.2

UnificationXref180
type: UnificationXref
id: CHEBI:3638
db: ChEBI

Stoichiometry312
type: Stoichiometry
physical entity: Protein294
stoichiometric coefficient: 1.0

Stoichiometry311
type: Stoichiometry
physical entity: adenylosuccinate synthetase like 1 holoenzyme (name copied from entity in Homo sapiens)
stoichiometric coefficient: 2.0

UnificationXref182
type: UnificationXref
id: REACT_22486
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_22486.2

Stoichiometry310
type: Stoichiometry
physical entity: Protein293
stoichiometric coefficient: 1.0

UnificationXref181
type: UnificationXref
id: 597610
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=597610

Stoichiometry316
type: Stoichiometry
physical entity: Protein297
stoichiometric coefficient: 4.0

Stoichiometry315
type: Stoichiometry
physical entity: Protein296
stoichiometric coefficient: 4.0

Stoichiometry314
type: Stoichiometry
physical entity: adenylosuccinate synthetase holoenzyme (name copied from entity in Homo sapiens)
stoichiometric coefficient: 2.0

Stoichiometry313
type: Stoichiometry
physical entity: SmallMolecule96
stoichiometric coefficient: 1.0

UnificationXref5696
type: UnificationXref
id: PF10_0053
db: UniProt

http://identifiers.org/pubmed/19359157
type: PublicationXref
id: 19359157
author: Lykke-Andersen, J
author: Rebbapragada, I
db: Pubmed
title: Execution of nonsense-mediated mRNA decay: what defines a substrate?
source: Curr Opin Cell Biol 21:394-402
year: 2009

UnificationXref5697
type: UnificationXref
id: 5595127
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595127

UnificationXref5694
type: UnificationXref
id: 379780
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379780

UnificationXref5695
type: UnificationXref
id: REACT_15919
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15919.1

UnificationXref5698
type: UnificationXref
id: 5595129
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595129

UnificationXref5699
type: UnificationXref
id: REACT_250351
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_250351.1

UnificationXref197
type: UnificationXref
id: REACT_192658
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192658.3

UnificationXref196
type: UnificationXref
id: 5597012
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597012

UnificationXref195
type: UnificationXref
id: REACT_208078
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_208078.2

UnificationXref194
type: UnificationXref
id: 5595675
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595675

Stoichiometry307
type: Stoichiometry
physical entity: Protein290
stoichiometric coefficient: 4.0

Stoichiometry306
type: Stoichiometry
physical entity: Protein289
stoichiometric coefficient: 1.0

UnificationXref199
type: UnificationXref
id: REACT_192659
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192659.3

Stoichiometry309
type: Stoichiometry
physical entity: SmallMolecule96
stoichiometric coefficient: 1.0

GRB2 events in ERBB2 signaling
type: Pathway
data source: Provenance1
pathway component: REACT 238671.1
evidence: Evidence791
xref: UnificationXref4617
xref: UnificationXref4618
pathway order: PathwayStep70
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref198
type: UnificationXref
id: 5597013
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597013

Stoichiometry308
type: Stoichiometry
physical entity: Protein291
stoichiometric coefficient: 4.0

Stoichiometry303
type: Stoichiometry
physical entity: SmallMolecule341
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/17698287
type: PublicationXref
id: 17698287
author: Grabowska, AM
author: Watson, SA
db: Pubmed
title: Role of gastrin peptides in carcinogenesis
source: Cancer Lett 257:1-15
year: 2007

UniProt:PFI0215c
type: ProteinReference
xref: UnificationXref4786
organism: http://identifiers.org/taxonomy/5833

Stoichiometry302
type: Stoichiometry
physical entity: Protein287
stoichiometric coefficient: 1.0

Stoichiometry305
type: Stoichiometry
physical entity: Protein288
stoichiometric coefficient: 1.0

Stoichiometry304
type: Stoichiometry
physical entity: alpha-ketoglutarate dehydrogenase E2 holoenzyme (name copied from entity in Homo sapiens)
stoichiometric coefficient: 24.0

UnificationXref193
type: UnificationXref
id: 5595673
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595673

UnificationXref192
type: UnificationXref
id: PFE0825w
db: UniProt

UnificationXref191
type: UnificationXref
id: 5595671
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595671

Stoichiometry301
type: Stoichiometry
physical entity: alpha-keto acid dehydrogenase E3 homodimer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 6.0

UnificationXref190
type: UnificationXref
id: REACT_22938
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_22938.2

Stoichiometry300
type: Stoichiometry
physical entity: alpha-ketoglutarate dehydrogenase E1 homodimer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 12.0

Nicotinamide salvaging
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction91
evidence: Evidence180
xref: RelationshipXref154
xref: UnificationXref1074
xref: UnificationXref1075
pathway order: PathwayStep178
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/7378348
type: PublicationXref
id: 7378348
author: So, AG
author: Tan, CK
author: Downey, KM
author: Lee, MY
db: Pubmed
title: Purification of deoxyribonucleic acid polymerase delta from calf thymus: partial characterization of physical properties.
source: Biochemistry 19:2096-101
year: 1980

Nonsense-Mediated Decay (NMD)
type: Pathway
data source: Provenance1
pathway component: Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
pathway component: REACT 192699.3
evidence: Evidence644
xref: RelationshipXref559
xref: UnificationXref4052
xref: UnificationXref4053
pathway order: PathwayStep626
pathway order: PathwayStep628
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4508
type: UnificationXref
id: 5594464
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594464

UnificationXref4507
type: UnificationXref
id: PFB0150c
db: UniProt

UnificationXref4509
type: UnificationXref
id: 5596385
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596385

UnificationXref4504
type: UnificationXref
id: REACT_230086
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_230086.1

UnificationXref4503
type: UnificationXref
id: 5596753
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596753

UnificationXref4506
type: UnificationXref
id: REACT_242713
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_242713.1

UnificationXref4505
type: UnificationXref
id: 5596754
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596754

UnificationXref4500
type: UnificationXref
id: REACT_191790
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_191790.3

http://identifiers.org/pubmed/22448029
type: PublicationXref
id: 22448029
author: Nadal, Angel
author: Ripoll, Cristina
author: Vieira, Elaine
author: Ñeco, Patricia
author: Caballero-Garrido, Ernesto
author: Marroquí, Laura
author: Quesada, Ivan
author: Gonzalez, Alejandro
db: Pubmed
title: Role of leptin in the pancreatic ?-cell: effects and signaling pathways
source: J. Mol. Endocrinol. 49:R9-17
year: 2012

UnificationXref4502
type: UnificationXref
id: REACT_191793
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_191793.3

UnificationXref4501
type: UnificationXref
id: 5596866
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596866

Stoichiometry364
type: Stoichiometry
physical entity: Protein333
stoichiometric coefficient: 3.0

Stoichiometry365
type: Stoichiometry
physical entity: Protein334
stoichiometric coefficient: 3.0

Stoichiometry366
type: Stoichiometry
physical entity: SmallMolecule339
stoichiometric coefficient: 6.0

Stoichiometry367
type: Stoichiometry
physical entity: SmallMolecule100
stoichiometric coefficient: 1.0

Stoichiometry368
type: Stoichiometry
physical entity: SmallMolecule96
stoichiometric coefficient: 2.0

Stoichiometry369
type: Stoichiometry
physical entity: Protein339
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/8089153
type: PublicationXref
id: 8089153
author: Hirst, M
author: Lou, L
author: Nakamura, J
author: Haliday, E
db: Pubmed
title: Human GMP synthetase. Protein purification, cloning, and functional expression of cDNA
source: J Biol Chem 269:23830-23837
year: 1994

Stoichiometry36
type: Stoichiometry
physical entity: SmallMolecule22
stoichiometric coefficient: 2.0

Stoichiometry37
type: Stoichiometry
physical entity: SmallMolecule54
stoichiometric coefficient: 2.0

Stoichiometry38
type: Stoichiometry
physical entity: SmallMolecule57
stoichiometric coefficient: 2.0

Stoichiometry39
type: Stoichiometry
physical entity: SmallMolecule58
stoichiometric coefficient: 2.0

Stoichiometry32
type: Stoichiometry
physical entity: PhysicalEntity1
stoichiometric coefficient: 1.0

Stoichiometry33
type: Stoichiometry
physical entity: SmallMolecule54
stoichiometric coefficient: 2.0

Stoichiometry34
type: Stoichiometry
physical entity: SmallMolecule55
stoichiometric coefficient: 2.0

Stoichiometry35
type: Stoichiometry
physical entity: SmallMolecule56
stoichiometric coefficient: 2.0

UnificationXref5640
type: UnificationXref
id: 379744
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379744

UnificationXref5642
type: UnificationXref
id: MAL13P1.281
db: UniProt

Stoichiometry31
type: Stoichiometry
physical entity: Complex13
stoichiometric coefficient: 1.0

UnificationXref5641
type: UnificationXref
id: REACT_15607
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15607.1

Stoichiometry30
type: Stoichiometry
physical entity: Protein53
stoichiometric coefficient: 1.0

UnificationXref5644
type: UnificationXref
id: 5595159
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595159

UnificationXref4512
type: UnificationXref
id: 5596825
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596825

UnificationXref5643
type: UnificationXref
id: 5595157
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595157

UnificationXref4513
type: UnificationXref
id: REACT_259164
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_259164.1

UnificationXref5646
type: UnificationXref
id: 379740
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379740

UnificationXref4510
type: UnificationXref
id: 5596387
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596387

UnificationXref5645
type: UnificationXref
id: REACT_239354
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_239354.1

UnificationXref4511
type: UnificationXref
id: REACT_241283
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_241283.1

UnificationXref5648
type: UnificationXref
id: 113522
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113522

UnificationXref4516
type: UnificationXref
id: PF08_0129
db: UniProt

UnificationXref5647
type: UnificationXref
id: REACT_15900
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15900.1

UnificationXref4517
type: UnificationXref
id: 5594828
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594828

UnificationXref4514
type: UnificationXref
id: PF14_0492
db: UniProt

Stoichiometry370
type: Stoichiometry
physical entity: MAT I/III (Mg, K cofactors) (name copied from entity in Homo sapiens)
stoichiometric coefficient: 4.0

UnificationXref5649
type: UnificationXref
id: REACT_4410
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4410.2

UnificationXref4515
type: UnificationXref
id: 5596239
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596239

Stoichiometry372
type: Stoichiometry
physical entity: SmallMolecule96
stoichiometric coefficient: 4.0

Stoichiometry371
type: Stoichiometry
physical entity: SmallMolecule100
stoichiometric coefficient: 2.0

UnificationXref4518
type: UnificationXref
id: 5594827
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594827

Stoichiometry374
type: Stoichiometry
physical entity: Protein340
stoichiometric coefficient: 1.0

UnificationXref4519
type: UnificationXref
id: 5596241
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596241

Stoichiometry373
type: Stoichiometry
physical entity: Protein339
stoichiometric coefficient: 2.0

Stoichiometry355
type: Stoichiometry
physical entity: Protein327
stoichiometric coefficient: 6.0

Stoichiometry356
type: Stoichiometry
physical entity: Protein328
stoichiometric coefficient: 2.0

Stoichiometry353
type: Stoichiometry
physical entity: Protein325
stoichiometric coefficient: 10.0

Stoichiometry354
type: Stoichiometry
physical entity: Protein326
stoichiometric coefficient: 2.0

Stoichiometry359
type: Stoichiometry
physical entity: branched-chain alpha-ketoacid dehydrogenase E1 complex (name copied from entity in Homo sapiens)
stoichiometric coefficient: 12.0

Stoichiometry357
type: Stoichiometry
physical entity: Protein329
stoichiometric coefficient: 2.0

Stoichiometry358
type: Stoichiometry
physical entity: SmallMolecule334
stoichiometric coefficient: 2.0

Stoichiometry49
type: Stoichiometry
physical entity: Protein72
stoichiometric coefficient: 1.0

Stoichiometry47
type: Stoichiometry
physical entity: Protein70
stoichiometric coefficient: 1.0

Stoichiometry48
type: Stoichiometry
physical entity: Protein71
stoichiometric coefficient: 1.0

Stoichiometry45
type: Stoichiometry
physical entity: Complex13
stoichiometric coefficient: 1.0

Stoichiometry46
type: Stoichiometry
physical entity: Protein69
stoichiometric coefficient: 1.0

Stoichiometry43
type: Stoichiometry
physical entity: SmallMolecule22
stoichiometric coefficient: 3.0

Stoichiometry44
type: Stoichiometry
physical entity: SmallMolecule31
stoichiometric coefficient: 3.0

UnificationXref5653
type: UnificationXref
id: 5595191
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595191

Stoichiometry42
type: Stoichiometry
physical entity: SmallMolecule60
stoichiometric coefficient: 1.0

UnificationXref5652
type: UnificationXref
id: 5595189
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595189

Stoichiometry41
type: Stoichiometry
physical entity: Protein62
stoichiometric coefficient: 1.0

UnificationXref5651
type: UnificationXref
id: REACT_15807
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15807.1

Stoichiometry40
type: Stoichiometry
physical entity: SmallMolecule22
stoichiometric coefficient: 2.0

UnificationXref5650
type: UnificationXref
id: 379753
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379753

UnificationXref4520
type: UnificationXref
id: 5596242
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596242

UnificationXref5657
type: UnificationXref
id: 379781
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379781

UnificationXref4521
type: UnificationXref
id: 5596246
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596246

UnificationXref5656
type: UnificationXref
id: REACT_16111
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_16111.1

UnificationXref4522
type: UnificationXref
id: 5596240
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596240

UnificationXref5655
type: UnificationXref
id: 379770
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379770

UnificationXref4523
type: UnificationXref
id: 5596243
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596243

UnificationXref5654
type: UnificationXref
id: REACT_236325
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_236325.1

UnificationXref4524
type: UnificationXref
id: 5596244
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596244

UnificationXref4525
type: UnificationXref
id: 5596382
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596382

UnificationXref4526
type: UnificationXref
id: REACT_234652
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_234652.1

UnificationXref5659
type: UnificationXref
id: 5595185
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595185

UnificationXref4527
type: UnificationXref
id: 5596245
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596245

UnificationXref5658
type: UnificationXref
id: REACT_15734
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15734.1

UnificationXref4528
type: UnificationXref
id: 5596370
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596370

UnificationXref4529
type: UnificationXref
id: 29496
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29496

Stoichiometry363
type: Stoichiometry
physical entity: SmallMolecule26
stoichiometric coefficient: 6.0

Stoichiometry362
type: Stoichiometry
physical entity: Protein332
stoichiometric coefficient: 3.0

Stoichiometry361
type: Stoichiometry
physical entity: Protein330
stoichiometric coefficient: 24.0

http://identifiers.org/pubmed/22522127
type: PublicationXref
id: 22522127
author: Oakley, Aaron J
author: Brock, Joseph
author: Liu, D
author: Board, PG
author: Zhou, Huina
db: Pubmed
title: Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases
source: J. Mol. Biol. 420:190-203
year: 2012

Stoichiometry360
type: Stoichiometry
physical entity: alpha-keto acid dehydrogenase E3 homodimer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 6.0

Stoichiometry18
type: Stoichiometry
physical entity: Complex12
stoichiometric coefficient: 1.0

Stoichiometry346
type: Stoichiometry
physical entity: Protein320
stoichiometric coefficient: 2.0

http://identifiers.org/pubmed/14729598
type: PublicationXref
id: 14729598
author: Zhou, B
author: Shao, J
author: Zhu, L
author: Yen, Y
author: Qiu, W
author: Xi, B
author: Yuan, YC
db: Pubmed
title: In vitro characterization of enzymatic properties and inhibition of the p53R2 subunit of human ribonucleotide reductase
source: Cancer Res 64:1-6
year: 2004

Stoichiometry19
type: Stoichiometry
physical entity: Complex11
stoichiometric coefficient: 1.0

Stoichiometry347
type: Stoichiometry
physical entity: SmallMolecule135
stoichiometric coefficient: 2.0

Stoichiometry348
type: Stoichiometry
physical entity: Protein203
stoichiometric coefficient: 2.0

Stoichiometry349
type: Stoichiometry
physical entity: Protein321
stoichiometric coefficient: 6.0

http://identifiers.org/pubmed/17635743
type: PublicationXref
id: 17635743
author: Bluteau, D
author: Debili, N
author: Chang, Y
author: Vainchenker, W
db: Pubmed
title: From hematopoietic stem cells to platelets
source: J Thromb Haemost 5:318-27
year: 2007

Stoichiometry342
type: Stoichiometry
physical entity: Protein319
stoichiometric coefficient: 2.0

Stoichiometry343
type: Stoichiometry
physical entity: ribonucleotide reductase M1 polypeptide dimer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry344
type: Stoichiometry
physical entity: SmallMolecule294
stoichiometric coefficient: 2.0

Stoichiometry345
type: Stoichiometry
physical entity: SmallMolecule135
stoichiometric coefficient: 2.0

Stoichiometry10
type: Stoichiometry
physical entity: Protein30
stoichiometric coefficient: 4.0

Stoichiometry11
type: Stoichiometry
physical entity: SmallMolecule22
stoichiometric coefficient: 3.0

Stoichiometry12
type: Stoichiometry
physical entity: SmallMolecule53
stoichiometric coefficient: 3.0

UnificationXref5660
type: UnificationXref
id: 5595186
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595186

Stoichiometry13
type: Stoichiometry
physical entity: Protein31
stoichiometric coefficient: 1.0

Stoichiometry14
type: Stoichiometry
physical entity: Protein32
stoichiometric coefficient: 1.0

Stoichiometry15
type: Stoichiometry
physical entity: Protein35
stoichiometric coefficient: 1.0

Stoichiometry16
type: Stoichiometry
physical entity: PhysicalEntity1
stoichiometric coefficient: 1.0

Stoichiometry17
type: Stoichiometry
physical entity: Protein40
stoichiometric coefficient: 6.0

UnificationXref5666
type: UnificationXref
id: 379764
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379764

UnificationXref4534
type: UnificationXref
id: 5596374
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596374

UnificationXref5665
type: UnificationXref
id: REACT_17378
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17378.1

UnificationXref4535
type: UnificationXref
id: 5596375
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596375

UnificationXref5668
type: UnificationXref
id: 5595177
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595177

UnificationXref4532
type: UnificationXref
id: 5596372
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596372

UnificationXref5667
type: UnificationXref
id: REACT_15671
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15671.1

UnificationXref4533
type: UnificationXref
id: 5596373
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596373

UnificationXref5662
type: UnificationXref
id: REACT_241208
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_241208.1

UnificationXref4530
type: UnificationXref
id: REACT_15981
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15981.2

UnificationXref5661
type: UnificationXref
id: 5595188
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595188

UnificationXref4531
type: UnificationXref
id: 5596371
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596371

UnificationXref5664
type: UnificationXref
id: 379752
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379752

UnificationXref5663
type: UnificationXref
id: 379695
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379695

Stoichiometry350
type: Stoichiometry
physical entity: Protein322
stoichiometric coefficient: 6.0

Stoichiometry352
type: Stoichiometry
physical entity: Protein324
stoichiometric coefficient: 6.0

http://identifiers.org/pubmed/8619989
type: PublicationXref
id: 8619989
author: Westley, J
author: Schwartz, NB
author: Ozeran, JD
db: Pubmed
title: Identification and partial purification of PAPS translocase
source: Biochemistry 35:3695-703
year: 1996

Stoichiometry351
type: Stoichiometry
physical entity: Protein323
stoichiometric coefficient: 2.0

UnificationXref4538
type: UnificationXref
id: REACT_11368
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_11368.2

UnificationXref5669
type: UnificationXref
id: 5595179
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595179

UnificationXref4539
type: UnificationXref
id: 2685584
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2685584

UnificationXref4536
type: UnificationXref
id: 5596376
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596376

UnificationXref4537
type: UnificationXref
id: 200493
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=200493

Stoichiometry337
type: Stoichiometry
physical entity: SmallMolecule391
stoichiometric coefficient: 2.0

Stoichiometry338
type: Stoichiometry
physical entity: ribonucleotide reductase M2 polypeptide dimer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry29
type: Stoichiometry
physical entity: Protein52
stoichiometric coefficient: 1.0

Stoichiometry335
type: Stoichiometry
physical entity: ribonucleotide reductase M1 polypeptide dimer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

Stoichiometry336
type: Stoichiometry
physical entity: Protein313
stoichiometric coefficient: 2.0

Stoichiometry333
type: Stoichiometry
physical entity: Protein309
stoichiometric coefficient: 1.0

Stoichiometry334
type: Stoichiometry
physical entity: Protein312
stoichiometric coefficient: 2.0

Stoichiometry331
type: Stoichiometry
physical entity: Protein307
stoichiometric coefficient: 2.0

Stoichiometry332
type: Stoichiometry
physical entity: Protein308
stoichiometric coefficient: 4.0

UnificationXref5670
type: UnificationXref
id: REACT_202750
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_202750.2

Stoichiometry23
type: Stoichiometry
physical entity: Protein43
stoichiometric coefficient: 3.0

UnificationXref5671
type: UnificationXref
id: 379788
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379788

Stoichiometry24
type: Stoichiometry
physical entity: Complex15
stoichiometric coefficient: 1.0

Stoichiometry21
type: Stoichiometry
physical entity: Protein42
stoichiometric coefficient: 3.0

Stoichiometry22
type: Stoichiometry
physical entity: Complex14
stoichiometric coefficient: 1.0

Stoichiometry27
type: Stoichiometry
physical entity: Complex16
stoichiometric coefficient: 1.0

Stoichiometry28
type: Stoichiometry
physical entity: Protein49
stoichiometric coefficient: 1.0

UniProt:PFA0260c
type: ProteinReference
xref: UnificationXref3289
organism: http://identifiers.org/taxonomy/5833

Stoichiometry25
type: Stoichiometry
physical entity: Protein46
stoichiometric coefficient: 1.0

Stoichiometry339
type: Stoichiometry
physical entity: Protein318
stoichiometric coefficient: 2.0

Stoichiometry26
type: Stoichiometry
physical entity: PhysicalEntity2
stoichiometric coefficient: 2.0

http://identifiers.org/pubmed/16807922
type: PublicationXref
id: 16807922
author: Hu, WS
author: Lee, MM
author: Hossler, P
author: Goh, LT
db: Pubmed
title: GlycoVis: visualizing glycan distribution in the protein N-glycosylation pathway in mammalian cells
source: Biotechnol Bioeng 95:946-60
year: 2006

UnificationXref5679
type: UnificationXref
id: 5595148
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595148

UnificationXref4543
type: UnificationXref
id: 5596379
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596379

UnificationXref5678
type: UnificationXref
id: 5595146
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595146

UnificationXref4544
type: UnificationXref
id: 5596380
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596380

UnificationXref5677
type: UnificationXref
id: PF08_0011
db: UniProt

UnificationXref4545
type: UnificationXref
id: 5596381
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596381

UnificationXref5676
type: UnificationXref
id: REACT_18097
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_18097.1

UnificationXref4546
type: UnificationXref
id: REACT_238240
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_238240.1

UnificationXref5675
type: UnificationXref
id: 379773
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379773

Stoichiometry20
type: Stoichiometry
physical entity: Protein41
stoichiometric coefficient: 1.0

UnificationXref2400
type: UnificationXref
id: CHEBI:28938
db: ChEBI

UnificationXref5674
type: UnificationXref
id: REACT_4213
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4213.2

UnificationXref4540
type: UnificationXref
id: REACT_165070
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_165070.1

UnificationXref2401
type: UnificationXref
id: 31633
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=31633

UnificationXref5673
type: UnificationXref
id: 113580
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=113580

UnificationXref4541
type: UnificationXref
id: 5596377
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596377

UnificationXref5672
type: UnificationXref
id: REACT_17073
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17073.1

UnificationXref4542
type: UnificationXref
id: 5596378
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596378

UnificationXref2404
type: UnificationXref
id: 5594123
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594123

Stoichiometry341
type: Stoichiometry
physical entity: ribonucleotide reductase M2B (TP53 inducible) dimer (name copied from entity in Homo sapiens)
stoichiometric coefficient: 1.0

UnificationXref2405
type: UnificationXref
id: 5594124
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594124

Stoichiometry340
type: Stoichiometry
physical entity: SmallMolecule402
stoichiometric coefficient: 2.0

UnificationXref2402
type: UnificationXref
id: REACT_2447
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2447.1

UnificationXref2403
type: UnificationXref
id: MAL13P1.146
db: UniProt

UnificationXref4547
type: UnificationXref
id: 5596762
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596762

UnificationXref2408
type: UnificationXref
id: 5594127
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594127

UnificationXref4548
type: UnificationXref
id: REACT_257103
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_257103.1

UnificationXref2409
type: UnificationXref
id: 5594128
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594128

UnificationXref4549
type: UnificationXref
id: 5596922
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596922

UnificationXref2406
type: UnificationXref
id: 5594125
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594125

UnificationXref2407
type: UnificationXref
id: 5594126
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594126

UnificationXref5605
type: UnificationXref
id: 5593587
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593587

UnificationXref4559
type: UnificationXref
id: 5596817
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596817

UnificationXref5606
type: UnificationXref
id: REACT_244352
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_244352.1

UnificationXref4558
type: UnificationXref
id: REACT_252012
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_252012.1

UnificationXref5603
type: UnificationXref
id: 5593584
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593584

UnificationXref5604
type: UnificationXref
id: 5593585
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593585

http://identifiers.org/pubmed/8428657
type: PublicationXref
id: 8428657
author: Yang, DC
author: Donovan, D
author: Vogeli, G
author: Vilalta, A
author: Wood, L
db: Pubmed
title: Cloning, sequencing and expression of a cDNA encoding mammalian valyl-tRNA synthetase
source: Gene 123:181-6
year: 1993

UnificationXref5609
type: UnificationXref
id: REACT_246867
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_246867.1

http://identifiers.org/pubmed/16024644
type: PublicationXref
id: 16024644
author: Shimamura, T
author: Shapiro, GI
author: Engelman, JA
author: Lowell, AM
db: Pubmed
title: Epidermal growth factor receptors harboring kinase domain mutations associate with the heat shock protein 90 chaperone and are destabilized following exposure to geldanamycins
source: Cancer Res 65:6401-8
year: 2005

UnificationXref5607
type: UnificationXref
id: 5593588
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593588

UnificationXref5608
type: UnificationXref
id: 5596707
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596707

UnificationXref4551
type: UnificationXref
id: 5596763
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596763

Stoichiometry74
type: Stoichiometry
physical entity: PhysicalEntity4
stoichiometric coefficient: 1.0

UnificationXref4550
type: UnificationXref
id: REACT_231511
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_231511.1

Stoichiometry75
type: Stoichiometry
physical entity: SmallMolecule86
stoichiometric coefficient: 1.0

UnificationXref4553
type: UnificationXref
id: 5596755
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596755

Stoichiometry72
type: Stoichiometry
physical entity: SmallMolecule69
stoichiometric coefficient: 1.0

UnificationXref4552
type: UnificationXref
id: REACT_232812
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_232812.1

Stoichiometry73
type: Stoichiometry
physical entity: Protein102
stoichiometric coefficient: 1.0

UnificationXref5601
type: UnificationXref
id: PFC0710w.1
db: UniProt

UnificationXref4555
type: UnificationXref
id: 5596815
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596815

Stoichiometry70
type: Stoichiometry
physical entity: Complex27
stoichiometric coefficient: 1.0

UnificationXref5602
type: UnificationXref
id: 5593583
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593583

UnificationXref4554
type: UnificationXref
id: REACT_191605
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_191605.3

Stoichiometry71
type: Stoichiometry
physical entity: Protein96
stoichiometric coefficient: 4.0

UnificationXref4557
type: UnificationXref
id: 5596816
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596816

UnificationXref5600
type: UnificationXref
id: 5593581
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593581

UnificationXref4556
type: UnificationXref
id: REACT_258602
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_258602.1

Stoichiometry79
type: Stoichiometry
physical entity: Protein110
stoichiometric coefficient: 4.0

Stoichiometry78
type: Stoichiometry
physical entity: Protein107
stoichiometric coefficient: 2.0

http://identifiers.org/pubmed/17222168
type: PublicationXref
id: 17222168
author: Agre, P
author: Frøkiaer, J
author: Nielsen, S
author: Kwon, TH
db: Pubmed
title: Regulation and dysregulation of aquaporins in water balance disorders
source: J Intern Med 261:53-64
year: 2007

Stoichiometry77
type: Stoichiometry
physical entity: Protein106
stoichiometric coefficient: 4.0

Stoichiometry76
type: Stoichiometry
physical entity: Protein105
stoichiometric coefficient: 2.0

UnificationXref5614
type: UnificationXref
id: 379730
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379730

UnificationXref5615
type: UnificationXref
id: REACT_15557
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15557.1

UnificationXref5616
type: UnificationXref
id: 5595135
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595135

Phospholipid metabolism
type: Pathway
data source: Provenance1
pathway component: Glycerophospholipid biosynthesis
pathway component: PI Metabolism
evidence: Evidence325
xref: UnificationXref1883
xref: RelationshipXref306
xref: UnificationXref1882
pathway order: PathwayStep306
pathway order: PathwayStep322
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref5617
type: UnificationXref
id: 5595137
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595137

UnificationXref4569
type: UnificationXref
id: 5596800
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596800

UnificationXref5618
type: UnificationXref
id: REACT_210198
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_210198.2

UnificationXref5619
type: UnificationXref
id: 379703
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379703

UnificationXref4564
type: UnificationXref
id: REACT_236621
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_236621.1

Stoichiometry83
type: Stoichiometry
physical entity: Protein113
stoichiometric coefficient: 2.0

UnificationXref4563
type: UnificationXref
id: 5596793
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596793

Stoichiometry84
type: Stoichiometry
physical entity: Protein114
stoichiometric coefficient: 2.0

UnificationXref4562
type: UnificationXref
id: REACT_191586
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_191586.3

Stoichiometry85
type: Stoichiometry
physical entity: SmallMolecule96
stoichiometric coefficient: 1.0

UnificationXref4561
type: UnificationXref
id: 5596756
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596756

Stoichiometry86
type: Stoichiometry
physical entity: Protein115
stoichiometric coefficient: 2.0

UnificationXref5610
type: UnificationXref
id: 379697
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379697

UnificationXref4568
type: UnificationXref
id: REACT_239272
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_239272.1

UnificationXref5611
type: UnificationXref
id: REACT_16024
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_16024.2

UnificationXref4567
type: UnificationXref
id: 5596799
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596799

Stoichiometry80
type: Stoichiometry
physical entity: Protein111
stoichiometric coefficient: 4.0

UnificationXref5612
type: UnificationXref
id: 379729
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379729

UnificationXref4566
type: UnificationXref
id: REACT_241119
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_241119.1

Stoichiometry81
type: Stoichiometry
physical entity: SmallMolecule96
stoichiometric coefficient: 1.0

UnificationXref5613
type: UnificationXref
id: REACT_15767
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15767.1

UnificationXref4565
type: UnificationXref
id: 5596794
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596794

Stoichiometry82
type: Stoichiometry
physical entity: Protein112
stoichiometric coefficient: 1.0

Stoichiometry88
type: Stoichiometry
physical entity: SmallMolecule96
stoichiometric coefficient: 1.0

UnificationXref4560
type: UnificationXref
id: REACT_245323
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_245323.1

Stoichiometry87
type: Stoichiometry
physical entity: Protein116
stoichiometric coefficient: 2.0

http://identifiers.org/pubmed/12641448
type: PublicationXref
id: 12641448
author: Tatham, Michael H
author: Chen, Yuan
author: Hay, Ronald T
db: Pubmed
title: Role of two residues proximal to the active site of Ubc9 in substrate recognition by the Ubc9.SUMO-1 thiolester complex
source: Biochemistry 42:3168-79
year: 2003

Stoichiometry89
type: Stoichiometry
physical entity: SmallMolecule100
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/16750198
type: PublicationXref
id: 16750198
author: Becker, K
author: Irmler, A
author: Urig, S
author: Lieske, J
author: Fritz-Wolf, K
db: Pubmed
title: Truncated mutants of human thioredoxin reductase 1 do not exhibit glutathione reductase activity
source: FEBS Lett 580:3595-600
year: 2006

UniProt:PFI0320w
type: ProteinReference
xref: UnificationXref2842
organism: http://identifiers.org/taxonomy/5833

UnificationXref5629
type: UnificationXref
id: 379715
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379715

UnificationXref5627
type: UnificationXref
id: 5595167
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595167

UnificationXref5628
type: UnificationXref
id: REACT_253678
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253678.1

UnificationXref5625
type: UnificationXref
id: PFE0475w
db: UniProt

UnificationXref5626
type: UnificationXref
id: 5595165
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595165

UnificationXref5623
type: UnificationXref
id: 379718
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379718

UnificationXref4577
type: UnificationXref
id: 5596767
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596767

UnificationXref5624
type: UnificationXref
id: REACT_16009
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_16009.1

UnificationXref4576
type: UnificationXref
id: REACT_241712
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_241712.1

UnificationXref5621
type: UnificationXref
id: 379699
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379699

UnificationXref4579
type: UnificationXref
id: 5596768
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596768

UnificationXref5622
type: UnificationXref
id: REACT_15719
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15719.1

UnificationXref4578
type: UnificationXref
id: REACT_242606
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_242606.1

UnificationXref4573
type: UnificationXref
id: 5596795
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596795

Stoichiometry52
type: Stoichiometry
physical entity: Protein74
stoichiometric coefficient: 6.0

UnificationXref5620
type: UnificationXref
id: REACT_15752
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15752.2

UnificationXref4572
type: UnificationXref
id: REACT_192035
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192035.3

Stoichiometry53
type: Stoichiometry
physical entity: Complex21
stoichiometric coefficient: 1.0

UnificationXref4575
type: UnificationXref
id: 5593983
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593983

Stoichiometry50
type: Stoichiometry
physical entity: Protein73
stoichiometric coefficient: 1.0

UnificationXref4574
type: UnificationXref
id: REACT_192020
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192020.3

Stoichiometry51
type: Stoichiometry
physical entity: Complex20
stoichiometric coefficient: 1.0

Stoichiometry57
type: Stoichiometry
physical entity: Protein76
stoichiometric coefficient: 1.0

Stoichiometry56
type: Stoichiometry
physical entity: Protein75
stoichiometric coefficient: 1.0

UnificationXref4570
type: UnificationXref
id: REACT_192014
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192014.3

Stoichiometry55
type: Stoichiometry
physical entity: Complex22
stoichiometric coefficient: 1.0

UnificationXref4571
type: UnificationXref
id: 5596801
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596801

Stoichiometry54
type: Stoichiometry
physical entity: PhysicalEntity3
stoichiometric coefficient: 2.0

Stoichiometry59
type: Stoichiometry
physical entity: Complex19
stoichiometric coefficient: 1.0

Stoichiometry58
type: Stoichiometry
physical entity: Complex23
stoichiometric coefficient: 1.0

http://identifiers.org/pubmed/10503886
type: PublicationXref
id: 10503886
author: Yoshinari, K
author: Fujita, K
author: Nagata, K
author: Shiraga, T
author: Yamazoe, Y
author: Iwasaki, K
db: Pubmed
title: Sulfotransferase catalyzing sulfation of heterocyclic amines
source: Cancer Lett 143:103-7
year: 1999

UnificationXref5636
type: UnificationXref
id: 5595172
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595172

UnificationXref5637
type: UnificationXref
id: REACT_239284
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_239284.1

UnificationXref5638
type: UnificationXref
id: 379754
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379754

UnificationXref5639
type: UnificationXref
id: REACT_15650
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15650.1

UnificationXref5632
type: UnificationXref
id: REACT_16074
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_16074.1

UnificationXref5633
type: UnificationXref
id: PF14_0166
db: UniProt

UnificationXref4589
type: UnificationXref
id: 5596806
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596806

UnificationXref5634
type: UnificationXref
id: 5595169
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595169

UnificationXref4588
type: UnificationXref
id: REACT_256451
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_256451.1

UnificationXref5635
type: UnificationXref
id: 5595170
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595170

UnificationXref4587
type: UnificationXref
id: 5596807
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596807

Stoichiometry60
type: Stoichiometry
physical entity: SmallMolecule54
stoichiometric coefficient: 4.0

UnificationXref4586
type: UnificationXref
id: REACT_255609
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_255609.1

Stoichiometry61
type: Stoichiometry
physical entity: SmallMolecule54
stoichiometric coefficient: 4.0

UnificationXref4585
type: UnificationXref
id: 5596805
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596805

Stoichiometry62
type: Stoichiometry
physical entity: Protein78
stoichiometric coefficient: 1.0

UnificationXref5630
type: UnificationXref
id: REACT_15813
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15813.1

UnificationXref4584
type: UnificationXref
id: REACT_247130
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_247130.1

Stoichiometry63
type: Stoichiometry
physical entity: Protein79
stoichiometric coefficient: 1.0

UnificationXref5631
type: UnificationXref
id: 379698
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379698

UnificationXref4583
type: UnificationXref
id: 5596810
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596810

Stoichiometry64
type: Stoichiometry
physical entity: Protein80
stoichiometric coefficient: 1.0

UnificationXref4581
type: UnificationXref
id: 5596803
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596803

Stoichiometry66
type: Stoichiometry
physical entity: SmallMolecule72
stoichiometric coefficient: 1.0

UnificationXref4582
type: UnificationXref
id: REACT_258870
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_258870.1

Stoichiometry65
type: Stoichiometry
physical entity: Protein83
stoichiometric coefficient: 1.0

Stoichiometry68
type: Stoichiometry
physical entity: Protein95
stoichiometric coefficient: 2.0

UnificationXref4580
type: UnificationXref
id: REACT_257822
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_257822.1

Stoichiometry67
type: Stoichiometry
physical entity: SmallMolecule73
stoichiometric coefficient: 2.0

Stoichiometry69
type: Stoichiometry
physical entity: SmallMolecule73
stoichiometric coefficient: 2.0

Base Excision Repair
type: Pathway
data source: Provenance1
pathway component: REACT 253233.1
pathway component: REACT 235060.1
evidence: Evidence678
xref: UnificationXref4186
xref: UnificationXref4187
xref: RelationshipXref572
pathway order: PathwayStep657
pathway order: PathwayStep661
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4594
type: UnificationXref
id: REACT_232892
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_232892.1

UnificationXref4595
type: UnificationXref
id: 5596917
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596917

UnificationXref4596
type: UnificationXref
id: REACT_241851
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_241851.1

http://identifiers.org/pubmed/18767960
type: PublicationXref
id: 18767960
author: Antonellis, A
author: Green, ED
db: Pubmed
title: The role of aminoacyl-tRNA synthetases in genetic diseases
source: Annu Rev Genomics Hum Genet 9:87-107
year: 2008

UnificationXref4597
type: UnificationXref
id: 5596740
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596740

UnificationXref4598
type: UnificationXref
id: REACT_258559
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_258559.1

UnificationXref4599
type: UnificationXref
id: 5596741
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596741

http://identifiers.org/pubmed/8063828
type: PublicationXref
id: 8063828
author: Frigeri, A
author: Ma, T
author: Verkman, AS
author: Hasegawa, H
db: Pubmed
title: Cloning of a water channel homolog expressed in brain meningeal cells and kidney collecting duct that functions as a stilbene-sensitive glycerol transporter
source: J Biol Chem 269:21845-9
year: 1994

http://identifiers.org/pubmed/2995985
type: PublicationXref
id: 2995985
author: Evans, DR
author: Kelly, RE
author: Pastra-Landis, SC
author: Lee, L
db: Pubmed
title: Oligomeric structure of the multifunctional protein CAD that initiates pyrimidine biosynthesis in mammalian cells
source: Proc Natl Acad Sci USA 82:6802-6806
year: 1985

http://identifiers.org/pubmed/6022858
type: PublicationXref
id: 6022858
author: Younathan, ES
author: Pynes, GD
db: Pubmed
title: Purification and some properties of inorganic pyrophosphatase from human erythrocytes
source: J Biol Chem 242:2119-23
year: 1967

http://identifiers.org/pubmed/18201392
type: PublicationXref
id: 18201392
author: Clarke, LA
db: Pubmed
title: The mucopolysaccharidoses: a success of molecular medicine
source: Expert Rev Mol Med 10:e1
year: 2008

UnificationXref4591
type: UnificationXref
id: 5596804
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596804

UnificationXref4590
type: UnificationXref
id: REACT_231072
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_231072.1

UnificationXref4593
type: UnificationXref
id: 5596739
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596739

UnificationXref4592
type: UnificationXref
id: REACT_247272
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_247272.1

http://identifiers.org/pubmed/1335363
type: PublicationXref
id: 1335363
author: Birnbaumer, L
db: Pubmed
title: Receptor-to-effector signaling through G proteins: roles for beta gamma dimers as well as alpha subunits
source: Cell 71:1069-72
year: 1992

http://identifiers.org/pubmed/11706405
type: PublicationXref
id: 11706405
author: Tari, AM
author: Lopez-Berestein, G
db: Pubmed
title: GRB2: a pivotal protein in signal transduction
source: Semin Oncol 28:142-7
year: 2001

Stoichiometry93
type: Stoichiometry
physical entity: SmallMolecule96
stoichiometric coefficient: 1.0

Stoichiometry92
type: Stoichiometry
physical entity: SmallMolecule100
stoichiometric coefficient: 1.0

Stoichiometry91
type: Stoichiometry
physical entity: SmallMolecule96
stoichiometric coefficient: 1.0

Stoichiometry90
type: Stoichiometry
physical entity: Protein117
stoichiometric coefficient: 4.0

Stoichiometry97
type: Stoichiometry
physical entity: SmallMolecule113
stoichiometric coefficient: 2.0

Stoichiometry96
type: Stoichiometry
physical entity: Protein120
stoichiometric coefficient: 2.0

Stoichiometry95
type: Stoichiometry
physical entity: Protein119
stoichiometric coefficient: 2.0

Stoichiometry94
type: Stoichiometry
physical entity: Protein118
stoichiometric coefficient: 4.0

http://identifiers.org/pubmed/9305914
type: PublicationXref
id: 9305914
author: Ishimi, Y
db: Pubmed
title: A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex.
source: J Biol Chem 272:24508-13
year: 1997

http://identifiers.org/pubmed/15314182
type: PublicationXref
id: 15314182
author: Salas-Marco, J
author: Bedwell, David M
db: Pubmed
title: GTP hydrolysis by eRF3 facilitates stop codon decoding during eukaryotic translation termination
source: Mol Cell Biol 24:7769-78
year: 2004

Metabolism of porphyrins
type: Pathway
data source: Provenance1
pathway component: REACT 241340.1
evidence: Evidence478
xref: RelationshipXref490
xref: UnificationXref3050
xref: UnificationXref3051
pathway order: PathwayStep474
display name: Porphyrin metabolism
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

Stoichiometry98
type: Stoichiometry
physical entity: Protein121
stoichiometric coefficient: 2.0

Stoichiometry99
type: Stoichiometry
physical entity: SmallMolecule96
stoichiometric coefficient: 1.0

Transport of nucleotide sugars
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction15
pathway component: BiochemicalReaction16
evidence: Evidence32
xref: UnificationXref234
xref: UnificationXref233
pathway order: PathwayStep31
pathway order: PathwayStep30
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/8114698
type: PublicationXref
id: 8114698
author: Nevins, JR
author: Ohtani, K
db: Pubmed
title: Functional properties of a Drosophila homolog of the E2F1 gene
source: Mol Cell Biol 14:1603-12
year: 1994

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL1635w
data source: Provenance1
name: PFL1635w
name: SENP5_HUMAN
name: Sentrin-specific protease 5 ecNumber3.4.22.68/ecNumber
xref: UnificationXref5216
feature: FragmentFeature687
cellular location: GO_0005654
comment: Reactome DB_ID: 5596415
display name: SENP5

UnificationXref397
type: UnificationXref
id: 5595796
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595796

Small ubiquitin-related modifier 2
type: Protein
entity reference: UniProt:PFE0285c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: proSUMO2
name: SUMO2_HUMAN
name: SUMO2(1-95)
name: PFE0285c
xref: UnificationXref5220
feature: FragmentFeature688
cellular location: GO_0005654
comment: Reactome DB_ID: 5596419
display name: SUMO2

UnificationXref396
type: UnificationXref
id: 5595795
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595795

UnificationXref399
type: UnificationXref
id: REACT_219685
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_219685.2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL1635w
data source: Provenance1
name: SENP2_HUMAN
name: PFL1635w
name: Sentrin-specific protease 2 ecNumber3.4.22.68/ecNumber
xref: UnificationXref5215
feature: FragmentFeature686
cellular location: GO_0005654
comment: Reactome DB_ID: 5596414
display name: SENP2

UnificationXref398
type: UnificationXref
id: 5595798
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595798

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFE0285c
data source: Provenance1
name: Small ubiquitin-related modifier 3
name: SUMO3_HUMAN
name: PFE0285c
xref: UnificationXref5225
feature: FragmentFeature691
cellular location: GO_0005654
comment: Reactome DB_ID: 5596423
display name: SUMO3

UnificationXref393
type: UnificationXref
id: PFC0840w
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF11_0457
data source: Provenance1
name: PF11_0457
name: SUMO-activating enzyme subunit 1
name: SAE1_HUMAN
xref: UnificationXref5231
feature: FragmentFeature692
cellular location: GO_0005654
comment: Reactome DB_ID: 5596397
display name: SAE1

UnificationXref392
type: UnificationXref
id: 5595791
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595791

Small ubiquitin-related modifier 2
type: Protein
entity reference: UniProt:PFE0285c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: SUMO2_HUMAN
name: PFE0285c
xref: UnificationXref5221
feature: FragmentFeature689
cellular location: GO_0005654
comment: Reactome DB_ID: 5596420
display name: SUMO2

UnificationXref395
type: UnificationXref
id: PF11_0395
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFE0285c
data source: Provenance1
name: Small ubiquitin-related modifier 3
name: proSUMO3
name: SUMO3_HUMAN
name: PFE0285c
name: SUMO3(1-103)
xref: UnificationXref5224
feature: FragmentFeature690
cellular location: GO_0005654
comment: Reactome DB_ID: 5596422
display name: SUMO3

UnificationXref394
type: UnificationXref
id: 5595793
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595793

UnificationXref391
type: UnificationXref
id: REACT_25925
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_25925.2

UnificationXref390
type: UnificationXref
id: 947592
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=947592

http://identifiers.org/pubmed/803528
type: PublicationXref
id: 803528
author: Winchester, RJ
author: Fu, SM
author: Kunkel, HG
db: Pubmed
title: Similar idiotypic specificity for the membrane IgD and IgM of human B lymphocytes
source: J Immunol 114:250-2
year: 1975

UnificationXref3128
type: UnificationXref
id: REACT_244230
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_244230.1

UnificationXref3129
type: UnificationXref
id: PF11_0407
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL1635w
data source: Provenance1
name: PFL1635w
name: Sentrin-specific protease 1 ecNumber3.4.22.68/ecNumber
name: SENP1_HUMAN
xref: UnificationXref5214
feature: FragmentFeature685
cellular location: GO_0005654
comment: Reactome DB_ID: 5596413
display name: SENP1

UnificationXref3124
type: UnificationXref
id: REACT_237544
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_237544.1

SENP1,2,5
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5217
cellular location: GO_0005654
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5596416

UnificationXref3125
type: UnificationXref
id: 5597121
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597121

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFE0285c
data source: Provenance1
name: SUMO1_HUMAN
name: Small ubiquitin-related modifier 1
name: PFE0285c
xref: UnificationXref5212
feature: FragmentFeature684
cellular location: GO_0005654
comment: Reactome DB_ID: 5596402
display name: SUMO1

UnificationXref3126
type: UnificationXref
id: REACT_239413
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_239413.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFE0285c
data source: Provenance1
name: proSUMO1
name: SUMO1(2-101)
name: SUMO1_HUMAN
name: Small ubiquitin-related modifier 1
name: PFE0285c
xref: UnificationXref5211
feature: FragmentFeature683
cellular location: GO_0005654
comment: Reactome DB_ID: 5596411
display name: SUMO1

UnificationXref3127
type: UnificationXref
id: 5596871
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596871

UnificationXref389
type: UnificationXref
id: REACT_26149
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_26149.2

UnificationXref3120
type: UnificationXref
id: 5596637
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596637

UnificationXref3121
type: UnificationXref
id: 5596638
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596638

UnificationXref3122
type: UnificationXref
id: 5596639
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596639

UnificationXref3123
type: UnificationXref
id: 5596641
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596641

Small ubiquitin-related modifier 2
type: Protein
entity reference: UniProt:PFE0285c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: SUMO2_HUMAN
name: UBA2-G93-SUMO2
xref: UnificationXref5242
feature: ModificationFeature57
feature: FragmentFeature696
cellular location: GO_0005654
comment: Reactome DB_ID: 5596440
display name: PFE0285c

UnificationXref3130
type: UnificationXref
id: 5596334
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596334

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFE0285c
data source: Provenance1
name: Small ubiquitin-related modifier 3
name: SUMO3_HUMAN
name: UBA2-G92-SUMO3
xref: UnificationXref5247
feature: ModificationFeature58
feature: FragmentFeature697
cellular location: GO_0005654
comment: Reactome DB_ID: 5596428
display name: PFE0285c

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFI0740c
data source: Provenance1
name: SUMO-conjugating enzyme UBC9
name: UBC9_HUMAN
name: PFI0740c
name: UBE2I (UBC9)
xref: UnificationXref5255
feature: FragmentFeature698
cellular location: GO_0005654
comment: Reactome DB_ID: 5596426
display name: UBE2I

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFI0740c
data source: Provenance1
name: SUMO-conjugating enzyme UBC9
name: SUMO3 S-glycyl-cys93 UBE2I
name: SUMO3-C93-UBE2I
name: UBC9_HUMAN
xref: UnificationXref5256
feature: ModificationFeature59
feature: FragmentFeature699
cellular location: GO_0005654
comment: Reactome DB_ID: 5596432
display name: PFI0740c

Small ubiquitin-related modifier 2
type: Protein
entity reference: UniProt:PFE0285c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: UBE2I-G93-SUMO2
name: SUMO2_HUMAN
xref: UnificationXref5260
feature: FragmentFeature700
feature: ModificationFeature60
cellular location: GO_0005654
comment: Reactome DB_ID: 5596445
display name: PFE0285c

Endoplasmin
type: Protein
entity reference: PFL1070c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: ENPL_HUMAN
name: PFL1070c
xref: UnificationXref5282
feature: FragmentFeature701
cellular location: GO_0005788
comment: Reactome DB_ID: 5596135
display name: HSP90B1

MAL13P1.134
type: Protein
entity reference: UniProt:MAL13P1.134
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: DDX11_HUMAN
name: Probable ATP-dependent RNA helicase DDX11
xref: UnificationXref5292
feature: FragmentFeature702
cellular location: GO_0005654
comment: Reactome DB_ID: 5596114
display name: DDX11

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFF1415c
data source: Provenance1
name: DNAJB11
name: ERdj3
name: PFF1415c
xref: UnificationXref5296
feature: FragmentFeature703
cellular location: GO_0005788
comment: Reactome DB_ID: 5596107
display name: HEDJ

UnificationXref4704
type: UnificationXref
id: PFL0335c
db: UniProt

UnificationXref4703
type: UnificationXref
id: 5593701
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593701

UnificationXref4702
type: UnificationXref
id: REACT_252228
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_252228.1

UnificationXref4701
type: UnificationXref
id: 5593700
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593700

UnificationXref4708
type: UnificationXref
id: 5596710
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596710

UnificationXref4707
type: UnificationXref
id: REACT_241718
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_241718.1

UnificationXref4706
type: UnificationXref
id: 5593830
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593830

UnificationXref3139
type: UnificationXref
id: REACT_152181
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_152181.1

http://identifiers.org/pubmed/21068004
type: PublicationXref
id: 21068004
author: Zechner, R
author: Sitnick, MT
author: Cai, L
author: Li, JZ
author: Kershaw, EE
author: Schoiswohl, G
author: Brenner, DS
author: Basantani, MK
author: Kumari, M
author: Gardner, NP
author: Gross, RW
author: Yang, K
db: Pubmed
title: Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome
source: J Lipid Res 52:318-29
year: 2011

UnificationXref4705
type: UnificationXref
id: 5593696
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593696

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFE0285c
data source: Provenance1
name: SUMO1_HUMAN
name: Small ubiquitin-related modifier 1
name: UBA2-G97-SUMO1
xref: UnificationXref5236
feature: FragmentFeature694
feature: ModificationFeature55
cellular location: GO_0005654
comment: Reactome DB_ID: 5596406
display name: PFE0285c

UnificationXref3137
type: UnificationXref
id: CHEBI:33737
db: ChEBI

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL1790w
data source: Provenance1
name: PFL1790w
name: SAE2_HUMAN
name: SUMO-activating enzyme subunit 2
xref: UnificationXref5233
feature: FragmentFeature693
cellular location: GO_0005654
comment: Reactome DB_ID: 5596399
display name: UBA2

UnificationXref3138
type: UnificationXref
id: 2395501
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2395501

UnificationXref3135
type: UnificationXref
id: PFL0705c
db: UniProt

SUMO1-C173-UBA2
type: Protein
entity reference: PFL1790w
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: SAE2_HUMAN
name: SUMO-activating enzyme subunit 2
name: SUMO1 S-glycyl-cys173 UBA2
xref: UnificationXref5237
feature: ModificationFeature56
feature: FragmentFeature695
cellular location: GO_0005654
comment: Reactome DB_ID: 5596404
display name: PFL1790w

UnificationXref3136
type: UnificationXref
id: 5596337
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596337

UnificationXref4700
type: UnificationXref
id: REACT_3030
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3030.1

UnificationXref3133
type: UnificationXref
id: 5596342
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596342

UnificationXref3134
type: UnificationXref
id: REACT_205842
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_205842.2

UniProt:PFL0560c
type: ProteinReference
xref: UnificationXref3777
organism: http://identifiers.org/taxonomy/5833

UnificationXref3131
type: UnificationXref
id: 5596339
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596339

UnificationXref3132
type: UnificationXref
id: 5596335
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596335

SC13_HUMAN
type: Protein
entity reference: PFL1480w
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: PFL1480w
name: SEC13-related protein
xref: UnificationXref5176
feature: FragmentFeature671
cellular location: GO_0005829
comment: Reactome DB_ID: 5594911
display name: SEC13

UnificationXref371
type: UnificationXref
id: 5595785
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595785

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFB0640c
data source: Provenance1
name: PFB0640c
name: Protein transport protein Sec31A
name: SC31A_HUMAN
xref: UnificationXref5178
feature: FragmentFeature672
cellular location: GO_0005829
comment: Reactome DB_ID: 5594910
display name: SEC31A

UnificationXref370
type: UnificationXref
id: 5595784
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595784

PFD0250c
type: Protein
entity reference: PFD0250c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Protein transport protein Sec24D
name: S24D_HUMAN
xref: UnificationXref5165
feature: FragmentFeature669
cellular location: GO_0005789
comment: Reactome DB_ID: 5594873
display name: SEC24D

UnificationXref373
type: UnificationXref
id: CHEBI:18420
db: ChEBI

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFD0810w
data source: Provenance1
name: PFD0810w
name: SAR1B GTP-binding protein
name: SARA2
xref: UnificationXref5171
feature: FragmentFeature670
cellular location: GO_0005829
comment: Reactome DB_ID: 5594879
display name: SAR1B

UnificationXref372
type: UnificationXref
id: 5595786
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595786

UnificationXref375
type: UnificationXref
id: REACT_11509
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_11509.2

PFD0250c
type: Protein
entity reference: PFD0250c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: S24C_HUMAN
name: Protein transport protein Sec24C
xref: UnificationXref5164
feature: FragmentFeature668
cellular location: GO_0005789
comment: Reactome DB_ID: 5594872
display name: SEC24C

UnificationXref374
type: UnificationXref
id: 200503
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=200503

UnificationXref377
type: UnificationXref
id: 5595789
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595789

UnificationXref376
type: UnificationXref
id: 5595787
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595787

UnificationXref3106
type: UnificationXref
id: 5596870
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596870

http://identifiers.org/pubmed/15581364
type: PublicationXref
id: 15581364
author: Zhai, H
author: McLafferty, FW
author: Brand, LA
author: Begley, TP
author: Strauss, E
db: Pubmed
title: Mechanistic studies on phosphopantothenoylcysteine decarboxylase: trapping of an enethiolate intermediate with a mechanism-based inactivating agent
source: Biochemistry 43:15520-33
year: 2004

UnificationXref3107
type: UnificationXref
id: REACT_258955
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_258955.1

UnificationXref3108
type: UnificationXref
id: CHEBI:53107
db: ChEBI

UnificationXref3109
type: UnificationXref
id: 5423727
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5423727

ATF4 activates genes
type: Pathway
data source: Provenance1
pathway component: Expression of Asparagine Synthetase
evidence: Evidence941
xref: UnificationXref5358
xref: UnificationXref5359
pathway order: PathwayStep920
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref367
type: UnificationXref
id: 167012
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=167012

UnificationXref368
type: UnificationXref
id: REACT_10868
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_10868.2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF13_0324
data source: Provenance1
name: S24B_HUMAN
name: Protein transport protein Sec24B
name: PF13_0324
xref: UnificationXref5163
feature: FragmentFeature667
cellular location: GO_0005789
comment: Reactome DB_ID: 5594870
display name: SEC24B

UnificationXref369
type: UnificationXref
id: PFL0590c
db: UniProt

UnificationXref3100
type: UnificationXref
id: 5594554
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594554

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF13_0324
data source: Provenance1
name: S24A_HUMAN
name: Protein transport protein Sec24A
name: PF13_0324
xref: UnificationXref5162
feature: FragmentFeature666
cellular location: GO_0005789
comment: Reactome DB_ID: 5594869
display name: SEC24A

UnificationXref3101
type: UnificationXref
id: 5594555
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594555

Sec24
type: Protein
data source: Provenance1
member physical entity: PFD0250c
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5166
cellular location: GO_0005789
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5594874

UnificationXref3102
type: UnificationXref
id: 5594557
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594557

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF08_0036
data source: Provenance1
name: Protein transport protein Sec23A
name: PF08_0036
name: S23A_HUMAN
xref: UnificationXref5161
feature: FragmentFeature665
cellular location: GO_0005789
comment: Reactome DB_ID: 5594876
display name: SEC23A

UnificationXref3103
type: UnificationXref
id: REACT_235326
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_235326.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFD0810w
data source: Provenance1
name: PFD0810w
name: SAR1B GTP-binding protein
name: SARA2
xref: UnificationXref5159
feature: FragmentFeature664
cellular location: GO_0005789
comment: Reactome DB_ID: 5594866
display name: SAR1B

UnificationXref3104
type: UnificationXref
id: 5596874
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596874

PFD0250c
type: Protein
entity reference: PFD0250c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Protein transport protein Sec24D
name: S24D_HUMAN
xref: UnificationXref5155
feature: FragmentFeature663
cellular location: GO_0005829
comment: Reactome DB_ID: 5594884
display name: SEC24D

UnificationXref3105
type: UnificationXref
id: REACT_240690
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_240690.1

PFD0250c
type: Protein
entity reference: PFD0250c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Protein transport protein Sec24D
name: S24D_HUMAN
xref: UnificationXref5190
feature: FragmentFeature679
cellular location: GO_0012507
comment: Reactome DB_ID: 5594902
display name: SEC24D

UnificationXref384
type: UnificationXref
id: 939747
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=939747

ARMS-mediated activation
type: Pathway
data source: Provenance1
pathway component: REACT 238671.1
evidence: Evidence776
xref: UnificationXref4588
xref: UnificationXref4587
pathway order: PathwayStep70
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF08_0036
data source: Provenance1
name: Protein transport protein Sec23A
name: PF08_0036
name: S23A_HUMAN
xref: UnificationXref5192
feature: FragmentFeature680
cellular location: GO_0012507
comment: Reactome DB_ID: 5594904
display name: SEC23A

UnificationXref383
type: UnificationXref
id: CHEBI:18303
db: ChEBI

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFB0640c
data source: Provenance1
name: PFB0640c
name: Protein transport protein Sec31A
name: SC31A_HUMAN
xref: UnificationXref5194
feature: FragmentFeature681
cellular location: GO_0012507
comment: Reactome DB_ID: 5594896
display name: SEC31A

UnificationXref382
type: UnificationXref
id: REACT_25558
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_25558.2

SC13_HUMAN
type: Protein
entity reference: PFL1480w
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: PFL1480w
name: SEC13-related protein
name: SEC13L1
xref: UnificationXref5195
feature: FragmentFeature682
cellular location: GO_0012507
comment: Reactome DB_ID: 5594897
display name: SEC13

UnificationXref381
type: UnificationXref
id: 947595
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=947595

UnificationXref388
type: UnificationXref
id: 939760
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=939760

UnificationXref387
type: UnificationXref
id: GO:0009898
db: GENE ONTOLOGY

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF13_0324
data source: Provenance1
name: S24B_HUMAN
name: Protein transport protein Sec24B
name: PF13_0324
xref: UnificationXref5188
feature: FragmentFeature677
cellular location: GO_0012507
comment: Reactome DB_ID: 5594900
display name: SEC24B

UnificationXref386
type: UnificationXref
id: 5595790
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595790

PFD0250c
type: Protein
entity reference: PFD0250c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: S24C_HUMAN
name: Protein transport protein Sec24C
xref: UnificationXref5189
feature: FragmentFeature678
cellular location: GO_0012507
comment: Reactome DB_ID: 5594901
display name: SEC24C

UnificationXref385
type: UnificationXref
id: REACT_26138
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_26138.2

UniProt:PFE1405c
type: ProteinReference
xref: UnificationXref3519
organism: http://identifiers.org/taxonomy/5833

UnificationXref380
type: UnificationXref
id: CHEBI:16038
db: ChEBI

UnificationXref3119
type: UnificationXref
id: 5596636
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596636

UnificationXref3117
type: UnificationXref
id: MAL13P1.324
db: UniProt

http://identifiers.org/pubmed/10522552
type: PublicationXref
id: 10522552
author: Ponka, P
db: Pubmed
title: Cell biology of heme
source: Am J Med Sci 318:241-56
year: 1999

UnificationXref3118
type: UnificationXref
id: 5596635
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596635

UnificationXref3111
type: UnificationXref
id: CHEBI:78575
db: ChEBI

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF13_0324
data source: Provenance1
name: S24A_HUMAN
name: Protein transport protein Sec24A
name: PF13_0324
xref: UnificationXref5187
feature: FragmentFeature676
cellular location: GO_0012507
comment: Reactome DB_ID: 5594899
display name: SEC24A

UnificationXref3112
type: UnificationXref
id: 5423729
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5423729

UnificationXref378
type: UnificationXref
id: REACT_258539
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_258539.1

UnificationXref379
type: UnificationXref
id: GO:0009897
db: GENE ONTOLOGY

UnificationXref3110
type: UnificationXref
id: REACT_228863
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_228863.1

Phagosomal maturation (early endosomal stage)
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction33
pathway component: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages
evidence: Evidence62
xref: UnificationXref438
xref: UnificationXref439
xref: RelationshipXref60
pathway order: PathwayStep60
pathway order: PathwayStep17
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

SC13_HUMAN
type: Protein
entity reference: PFL1480w
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: PFL1480w
name: SEC13-related protein
name: SEC13L1
xref: UnificationXref5180
feature: FragmentFeature674
cellular location: GO_0005789
comment: Reactome DB_ID: 5594893
display name: SEC13

UnificationXref3115
type: UnificationXref
id: 5596632
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596632

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFB0640c
data source: Provenance1
name: PFB0640c
name: Protein transport protein Sec31A
name: SC31A_HUMAN
xref: UnificationXref5179
feature: FragmentFeature673
cellular location: GO_0005789
comment: Reactome DB_ID: 5594891
display name: SEC31A

UnificationXref3116
type: UnificationXref
id: 5596633
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596633

http://identifiers.org/pubmed/3435492
type: PublicationXref
id: 3435492
author: Li, SS
author: Pan, YC
author: Sakai, I
author: Sharief, FS
db: Pubmed
title: The cDNA and protein sequences of human lactate dehydrogenase B
source: Biochem J 248:933-6
year: 1987

Sec24
type: Protein
data source: Provenance1
member physical entity: PFD0250c
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5191
cellular location: GO_0012507
comment: Reactome DB_ID: 5594903
comment: Converted from EntitySet in Reactome

UnificationXref3113
type: UnificationXref
id: REACT_229295
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_229295.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFD0810w
data source: Provenance1
name: PFD0810w
name: SAR1B GTP-binding protein
name: SARA2
xref: UnificationXref5186
feature: FragmentFeature675
cellular location: GO_0012507
comment: Reactome DB_ID: 5594906
display name: SAR1B

UnificationXref3114
type: UnificationXref
id: PF14_0088
db: UniProt

UnificationXref352
type: UnificationXref
id: 5595253
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595253

UnificationXref3160
type: UnificationXref
id: 5596277
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596277

UnificationXref353
type: UnificationXref
id: 5595255
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595255

UnificationXref3161
type: UnificationXref
id: REACT_248919
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_248919.1

UnificationXref354
type: UnificationXref
id: REACT_259774
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_259774.1

UnificationXref3162
type: UnificationXref
id: 5597086
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597086

UnificationXref355
type: UnificationXref
id: GO:0005788
db: GENE ONTOLOGY

UnificationXref3163
type: UnificationXref
id: REACT_258439
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_258439.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: MAL13P1.218
data source: Provenance1
name: UDP-N-acetylhexosamine pyrophosphorylase
name: UAP1_HUMAN
name: MAL13P1.218
xref: UnificationXref5102
feature: FragmentFeature653
cellular location: GO_0005829
comment: Reactome DB_ID: 5595480
display name: UAP1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF11_0311
data source: Provenance1
name: Phosphoacetylglucosamine mutase
name: PF11_0311
name: AGM1_HUMAN
xref: UnificationXref5095
feature: FragmentFeature652
cellular location: GO_0005829
comment: Reactome DB_ID: 5595457
display name: PGM3

Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) 2
type: Protein
entity reference: PF10_0245
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: PF10_0245
xref: UnificationXref5084
feature: FragmentFeature651
cellular location: GO_0005829
comment: Reactome DB_ID: 5595495
display name: GFPT2

UnificationXref350
type: UnificationXref
id: 5595251
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595251

UnificationXref351
type: UnificationXref
id: 5595252
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595252

MAL8P1.22
type: Protein
entity reference: UniProt:MAL8P1.22
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Dehydrodolichyl diphosphate synthase
name: DHDDS_HUMAN
xref: UnificationXref5057
feature: FragmentFeature647
cellular location: GO_0005789
comment: Reactome DB_ID: 5596560
display name: DHDDS

UnificationXref3169
type: UnificationXref
id: REACT_260949
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_260949.1

Homologues of DOLK
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5074
cellular location: GO_0005789
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5595470

UnificationXref349
type: UnificationXref
id: 5595250
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595250

UnificationXref3168
type: UnificationXref
id: 5596886
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596886

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFF0740c
data source: Provenance1
name: PIG-W
name: PFF0740c
name: phosphatidylinositol glycan, class W
xref: UnificationXref5028
feature: FragmentFeature645
cellular location: GO_0005789
comment: Reactome DB_ID: 5594422
display name: PIGW

MAL13P1.210
type: Protein
entity reference: MAL13P1.210
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: phosphatidylinositol glycan, class B
name: PIG-B
xref: UnificationXref5044
feature: FragmentFeature646
cellular location: GO_0005789
comment: Reactome DB_ID: 5594428
display name: PIGB

GFPT1,2
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) 2
xref: UnificationXref5085
cellular location: GO_0005829
comment: Reactome DB_ID: 5595496
comment: Converted from EntitySet in Reactome

UnificationXref346
type: UnificationXref
id: REACT_2606
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2606.2

UnificationXref3165
type: UnificationXref
id: REACT_193046
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_193046.3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF10_0245
data source: Provenance1
name: Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) 1
name: PF10_0245
xref: UnificationXref5083
feature: FragmentFeature650
cellular location: GO_0005829
comment: Reactome DB_ID: 5595494
display name: GFPT1

UnificationXref345
type: UnificationXref
id: 139827
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=139827

UnificationXref3164
type: UnificationXref
id: 5597087
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597087

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFA0485w.1
data source: Provenance1
name: DOLK_HUMAN
name: Dolichol kinase
name: PFA0485w.1
xref: UnificationXref5071
feature: FragmentFeature648
cellular location: GO_0005789
comment: Reactome DB_ID: 5595467
display name: DOLK

UnificationXref348
type: UnificationXref
id: PFA0310c
db: UniProt

UnificationXref3167
type: UnificationXref
id: REACT_191755
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_191755.3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFA0485w.2
data source: Provenance1
name: DOLK_HUMAN
name: PFA0485w.2
name: Dolichol kinase
xref: UnificationXref5073
feature: FragmentFeature649
cellular location: GO_0005789
comment: Reactome DB_ID: 5595469
display name: DOLK

UnificationXref347
type: UnificationXref
id: GO:0031095
db: GENE ONTOLOGY

UnificationXref3166
type: UnificationXref
id: 5596677
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596677

http://identifiers.org/pubmed/2995393
type: PublicationXref
id: 2995393
author: Fitzpatrick, F
author: McGee, J
db: Pubmed
title: Enzymatic hydration of leukotriene A4. Purification and characterization of a novel epoxide hydrolase from human erythrocytes
source: J Biol Chem 260:12832-7
year: 1985

UnificationXref365
type: UnificationXref
id: 5595309
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595309

UnificationXref3173
type: UnificationXref
id: 5594338
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594338

UnificationXref366
type: UnificationXref
id: REACT_233149
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_233149.1

UnificationXref3174
type: UnificationXref
id: REACT_257110
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_257110.1

UnificationXref363
type: UnificationXref
id: 5595306
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595306

UnificationXref3171
type: UnificationXref
id: 5594337
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594337

UnificationXref364
type: UnificationXref
id: 5595307
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595307

UnificationXref3172
type: UnificationXref
id: 5594336
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594336

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF13_0324
data source: Provenance1
name: S24A_HUMAN
name: Protein transport protein Sec24A
name: PF13_0324
xref: UnificationXref5151
feature: FragmentFeature660
cellular location: GO_0005829
comment: Reactome DB_ID: 5594881
display name: SEC24A

UnificationXref361
type: UnificationXref
id: 5595304
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595304

Sec24
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: PFD0250c
xref: UnificationXref5156
cellular location: GO_0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5594885

UnificationXref362
type: UnificationXref
id: 5595305
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595305

UnificationXref3170
type: UnificationXref
id: PF14_0038
db: UniProt

UniProt:PF07_0117
type: ProteinReference
xref: UnificationXref3534
organism: http://identifiers.org/taxonomy/5833

PFD0250c
type: Protein
entity reference: PFD0250c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: S24C_HUMAN
name: Protein transport protein Sec24C
xref: UnificationXref5154
feature: FragmentFeature662
cellular location: GO_0005829
comment: Reactome DB_ID: 5594883
display name: SEC24C

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF13_0324
data source: Provenance1
name: S24B_HUMAN
name: Protein transport protein Sec24B
name: PF13_0324
xref: UnificationXref5152
feature: FragmentFeature661
cellular location: GO_0005829
comment: Reactome DB_ID: 5594882
display name: SEC24B

UnificationXref360
type: UnificationXref
id: GO:0005789
db: GENE ONTOLOGY

UniProt:PF07_0112
type: ProteinReference
xref: UnificationXref3681
organism: http://identifiers.org/taxonomy/5833

PMM1,2
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5118
cellular location: GO_0005829
comment: Reactome DB_ID: 5595476
comment: Converted from EntitySet in Reactome

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF10_0169
data source: Provenance1
name: PMM1_HUMAN
name: Phosphomannomutase 1
name: PF10_0169
xref: UnificationXref5116
feature: FragmentFeature654
cellular location: GO_0005829
comment: Reactome DB_ID: 5595474
display name: PMM1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF10_0169
data source: Provenance1
name: PMM2_HUMAN
name: Phosphomannomutase 2
name: PF10_0169
xref: UnificationXref5117
feature: FragmentFeature655
cellular location: GO_0005829
comment: Reactome DB_ID: 5595475
display name: PMM2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0774
data source: Provenance1
name: PF14_0774
name: Mannose-1-phosphate guanyltransferase beta
name: GMPPB_HUMAN
xref: UnificationXref5125
feature: FragmentFeature656
cellular location: GO_0005829
comment: Reactome DB_ID: 5595490
display name: GMPPB

UnificationXref3179
type: UnificationXref
id: 29428
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=29428

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFC0935c
data source: Provenance1
name: PFC0935c
name: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
name: GPT_HUMAN
xref: UnificationXref5136
feature: FragmentFeature657
cellular location: GO_0005789
comment: Reactome DB_ID: 5595461
display name: DPAGT1

UnificationXref359
type: UnificationXref
id: REACT_11819
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_11819.2

UnificationXref3178
type: UnificationXref
id: REACT_234298
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_234298.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFB0515w
data source: Provenance1
name: UDP-N-acetylglucosamine transferase subunit ALG14 homolog
name: PFB0515w
name: ALG14_HUMAN
xref: UnificationXref5143
feature: FragmentFeature658
cellular location: GO_0005789
comment: Reactome DB_ID: 5595486
display name: ALG14

UnificationXref358
type: UnificationXref
id: 111875
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=111875

UnificationXref3177
type: UnificationXref
id: 5596847
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596847

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF08_0036
data source: Provenance1
name: Protein transport protein Sec23A
name: PF08_0036
name: S23A_HUMAN
xref: UnificationXref5149
feature: FragmentFeature659
cellular location: GO_0005829
comment: Reactome DB_ID: 5594886
display name: SEC23A

UnificationXref357
type: UnificationXref
id: REACT_3830
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3830.1

UnificationXref3176
type: UnificationXref
id: REACT_243561
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_243561.1

UnificationXref356
type: UnificationXref
id: 156540
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=156540

UnificationXref3175
type: UnificationXref
id: 5596846
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596846

EIF5A
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref4982
cellular location: GO_0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5594922

UniProt:PF07_0105
type: ProteinReference
xref: UnificationXref4314
organism: http://identifiers.org/taxonomy/5833

UnificationXref330
type: UnificationXref
id: 5593979
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593979

UnificationXref331
type: UnificationXref
id: 5593980
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593980

UnificationXref332
type: UnificationXref
id: 5593981
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593981

UnificationXref3140
type: UnificationXref
id: 5596338
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596338

UnificationXref333
type: UnificationXref
id: 5595749
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595749

UnificationXref3141
type: UnificationXref
id: CHEBI:33738
db: ChEBI

Homologues of TUBA3C unfolded
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref4952
cellular location: GO_0005829
comment: Reactome DB_ID: 5595227
comment: Converted from EntitySet in Reactome

UnificationXref324
type: UnificationXref
id: 5593966
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593966

UnificationXref3143
type: UnificationXref
id: REACT_150885
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_150885.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFD1050w
data source: Provenance1
name: Tubulin alpha-3C/D chain
name: TUBA3C unfolded
name: PFD1050w
name: unfolded alpha tubulin 2.2
name: TBA3C_HUMAN
xref: UnificationXref4950
feature: FragmentFeature634
cellular location: GO_0005829
comment: Reactome DB_ID: 5595225
display name: TUBA3C

UnificationXref323
type: UnificationXref
id: PFA0300c
db: UniProt

UnificationXref3142
type: UnificationXref
id: 2395504
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2395504

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PF10_0084
data source: Provenance1
name: beta tubulin 5
name: PF10_0084
xref: UnificationXref4948
feature: FragmentFeature632
cellular location: GO_0005829
comment: Reactome DB_ID: 5594637
display name: TUBB4A

UnificationXref326
type: UnificationXref
id: 5593968
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593968

UnificationXref3145
type: UnificationXref
id: 5596341
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596341

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PF10_0084
data source: Provenance1
name: beta tubulin 6
name: PF10_0084
xref: UnificationXref4949
feature: FragmentFeature633
cellular location: GO_0005829
comment: Reactome DB_ID: 5594640
display name: TUBB6

UnificationXref325
type: UnificationXref
id: 5593967
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593967

UnificationXref3144
type: UnificationXref
id: 5596340
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596340

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PF10_0084
data source: Provenance1
name: beta tubulin 2C
name: PF10_0084
xref: UnificationXref4946
feature: FragmentFeature630
cellular location: GO_0005829
comment: Reactome DB_ID: 5594638
display name: TUBB4B

UnificationXref328
type: UnificationXref
id: 5593976
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593976

UnificationXref3147
type: UnificationXref
id: 5597095
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597095

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PF10_0084
data source: Provenance1
name: beta tubulin 4
name: PF10_0084
xref: UnificationXref4947
feature: FragmentFeature631
cellular location: GO_0005829
comment: Reactome DB_ID: 5594636
display name: TUBB3

UnificationXref327
type: UnificationXref
id: PF11_0412
db: UniProt

UnificationXref3146
type: UnificationXref
id: REACT_212007
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_212007.2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFI0180w
data source: Provenance1
name: alpha tubulin 6
name: Tubulin alpha-1C chain
name: PFI0180w
xref: UnificationXref4942
feature: FragmentFeature628
cellular location: GO_0005829
comment: Reactome DB_ID: 5594629
display name: TUBA1C

UnificationXref3149
type: UnificationXref
id: 5597096
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597096

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PF10_0084
data source: Provenance1
name: PF10_0084
name: beta tubulin 1
xref: UnificationXref4945
feature: FragmentFeature629
cellular location: GO_0005829
comment: Reactome DB_ID: 5594639
display name: TUBB1

UnificationXref329
type: UnificationXref
id: PF13_0034
db: UniProt

UnificationXref3148
type: UnificationXref
id: REACT_193048
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_193048.3

UniProt:PFC1020c
type: ProteinReference
xref: UnificationXref3454
organism: http://identifiers.org/taxonomy/5833

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFI0180w
data source: Provenance1
name: PFI0180w
name: Tubulin alpha-3C/D chain
name: TUBA3C unfolded
name: unfolded alpha tubulin 2.2
name: TBA3C_HUMAN
xref: UnificationXref4951
feature: FragmentFeature635
cellular location: GO_0005829
comment: Reactome DB_ID: 5595226
display name: TUBA3C

beta-tubulin folding intermediate
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref4958
cellular location: GO_0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5595231

http://identifiers.org/pubmed/9191022
type: PublicationXref
id: 9191022
author: Hindges, R
author: Hubscher, U
db: Pubmed
title: DNA polymerase delta, an essential enzyme for DNA transactions.
source: Biol Chem 378:345-62
year: 1997

UnificationXref340
type: UnificationXref
id: 74016
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=74016

http://identifiers.org/pubmed/18768791
type: PublicationXref
id: 18768791
author: Horsefield, R
author: Neutze, R
author: Nordén, K
author: Törnroth-Horsefield, S
author: Johanson, U
author: Terwisscha van Scheltinga, AC
author: Kvassman, J
author: Fellert, M
author: Kjellbom, P
author: Backmark, A
db: Pubmed
title: High-resolution x-ray structure of human aquaporin 5
source: Proc Natl Acad Sci U S A 105:13327-32
year: 2008

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFF1190c
data source: Provenance1
name: PFF1190c
name: PIG-L
name: phosphatidylinositol glycan, class L
name: N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
xref: UnificationXref5019
feature: FragmentFeature644
cellular location: GO_0005789
comment: Reactome DB_ID: 5594432
display name: PIGL

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PF13_0013
data source: Provenance1
name: PF13_0013
name: Deoxyhypusine hydroxylase apoenzyme
name: DOHH apoenzyme
xref: UnificationXref5002
feature: FragmentFeature643
cellular location: GO_0005829
comment: Reactome DB_ID: 5594934
display name: DOHH

UnificationXref343
type: UnificationXref
id: 427899
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=427899

UnificationXref3151
type: UnificationXref
id: CHEBI:64112
db: ChEBI

UnificationXref344
type: UnificationXref
id: REACT_24619
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_24619.1

UnificationXref3152
type: UnificationXref
id: 2161194
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2161194

UnificationXref341
type: UnificationXref
id: REACT_5631
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_5631.2

http://identifiers.org/pubmed/7706277
type: PublicationXref
id: 7706277
author: Lou, L
author: Nakamura, J
db: Pubmed
title: Biochemical characterization of human GMP synthetase
source: J Biol Chem 270:7347-7353
year: 1995

UnificationXref342
type: UnificationXref
id: GO:0031096
db: GENE ONTOLOGY

UnificationXref3150
type: UnificationXref
id: REACT_193052
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_193052.3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL0210c
data source: Provenance1
name: EIF5A2(Dhp)
name: Dhp-EIF5A2
name: Eukaryotic tranlation initiation factor 5A2
xref: UnificationXref4985
feature: FragmentFeature639
feature: ModificationFeature53
cellular location: GO_0005829
comment: Reactome DB_ID: 5594918
display name: PFL0210c

UnificationXref337
type: UnificationXref
id: 5596992
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596992

UnificationXref3156
type: UnificationXref
id: REACT_122307
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_122307.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0125
data source: Provenance1
name: Deoxyhypusine synthase monomer
name: PF14_0125
xref: UnificationXref4991
feature: FragmentFeature640
cellular location: GO_0005829
comment: Reactome DB_ID: 5594924
display name: DHPS

UnificationXref336
type: UnificationXref
id: REACT_192676
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192676.3

UnificationXref3155
type: UnificationXref
id: 2161175
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2161175

EIF5A(Hyp)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5000
cellular location: GO_0005829
comment: Reactome DB_ID: 5594932
comment: Converted from EntitySet in Reactome

UnificationXref335
type: UnificationXref
id: 5597040
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597040

UnificationXref3154
type: UnificationXref
id: CHEBI:34660
db: ChEBI

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL0210c
data source: Provenance1
name: Hypu-EIF5A2
name: EIF5A2(Hyp50)
xref: UnificationXref4998
feature: FragmentFeature641
feature: ModificationFeature54
cellular location: GO_0005829
comment: Reactome DB_ID: 5594930
display name: PFL0210c

UnificationXref334
type: UnificationXref
id: REACT_207390
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_207390.2

UnificationXref3153
type: UnificationXref
id: REACT_124629
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_124629.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL0210c
data source: Provenance1
name: Eukaryotic translation initiation factor 5A-1
name: Dhp50
name: PFL0210c
name: IF5A1_HUMAN
xref: UnificationXref4980
feature: FragmentFeature636
cellular location: GO_0005829
comment: Reactome DB_ID: 5594920
display name: EIF5A

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL0210c
data source: Provenance1
name: PFL0210c
name: Eukaryotic tranlation initiation factor 5A2
xref: UnificationXref4981
feature: FragmentFeature637
cellular location: GO_0005829
comment: Reactome DB_ID: 5594921
display name: EIF5A2

UnificationXref3159
type: UnificationXref
id: REACT_124587
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_124587.1

PPi
type: SmallMoleculeReference
name: PPi [ChEBI:29888]
xref: UnificationXref976

EIF5A(Dhp)
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
member physical entity: Dhp-EIF5A
xref: UnificationXref4986
cellular location: GO_0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5594919

UnificationXref339
type: UnificationXref
id: CHEBI:29108
db: ChEBI

UnificationXref3158
type: UnificationXref
id: 2161176
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=2161176

Dhp-EIF5A
type: Protein
entity reference: PFL0210c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: EIF5A(Dhp)
name: Eukaryotic translation initiation factor 5A-1
name: IF5A1_HUMAN
xref: UnificationXref4984
feature: FragmentFeature638
feature: ModificationFeature53
cellular location: GO_0005829
comment: Reactome DB_ID: 5594917
display name: PFL0210c

UnificationXref338
type: UnificationXref
id: REACT_250608
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_250608.1

UnificationXref3157
type: UnificationXref
id: CHEBI:64116
db: ChEBI

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL0210c
data source: Provenance1
name: PFL0210c
name: Eukaryotic translation initiation factor 5A
name: Hypu-EIF5A
name: IF5A1_HUMAN
xref: UnificationXref4999
feature: FragmentFeature642
feature: ModificationFeature54
cellular location: GO_0005829
comment: Reactome DB_ID: 5594931
display name: Hyp50

http://identifiers.org/pubmed/13575436
type: PublicationXref
id: 13575436
author: Robbins, PW
author: Lipmann, F
db: Pubmed
title: Separation of the two enzymatic phases in active sulfate synthesis
source: J Biol Chem 233:681-5
year: 1958

http://identifiers.org/pubmed/15585754
type: PublicationXref
id: 15585754
author: Hicklin, DJ
author: Ellis, LM
db: Pubmed
title: Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
source: J Clin Oncol 23:1011-27
year: 2005

UnificationXref309
type: UnificationXref
id: PF13_0065
db: UniProt

UnificationXref307
type: UnificationXref
id: PF13_0227
db: UniProt

UnificationXref308
type: UnificationXref
id: 5593970
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593970

http://identifiers.org/pubmed/11208594
type: PublicationXref
id: 11208594
author: Rabelink, TJ
author: Govers, R
db: Pubmed
title: Cellular regulation of endothelial nitric oxide synthase
source: Am J Physiol Renal Physiol 280:F193-206
year: 2001

UnificationXref305
type: UnificationXref
id: 5593950
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593950

UnificationXref306
type: UnificationXref
id: 5593956
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593956

UnificationXref303
type: UnificationXref
id: PFE0965c
db: UniProt

UnificationXref304
type: UnificationXref
id: 5593949
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593949

UnificationXref301
type: UnificationXref
id: 5593945
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593945

UnificationXref302
type: UnificationXref
id: 5593955
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593955

UnificationXref311
type: UnificationXref
id: 5593959
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593959

UnificationXref310
type: UnificationXref
id: 5593958
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593958

SequenceSite300
type: SequenceSite
position status: EQUAL
sequence position: 1433

http://identifiers.org/pubmed/12123609
type: PublicationXref
id: 12123609
author: Snider, WD
author: Zhong, J
author: Markus, A
db: Pubmed
title: Raf and akt mediate distinct aspects of sensory axon growth
source: Neuron 35:65-76
year: 2002

http://identifiers.org/pubmed/10958673
type: PublicationXref
id: 10958673
author: Yoshida, H
author: Haze, K
author: Yura, T
author: Yanagi, H
author: Mori, K
author: Okada, T
author: Negishi, M
db: Pubmed
title: ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response
source: Mol Cell Biol 20:6755-67
year: 2000

SequenceSite309
type: SequenceSite
position status: EQUAL
sequence position: 2346

SequenceSite308
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref316
type: UnificationXref
id: 5593964
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593964

SequenceSite307
type: SequenceSite
position status: EQUAL
sequence position: 786

UnificationXref317
type: UnificationXref
id: PFI1670c
db: UniProt

SequenceSite306
type: SequenceSite
position status: EQUAL
sequence position: 440

UnificationXref318
type: UnificationXref
id: 5593972
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593972

SequenceSite305
type: SequenceSite
position status: EQUAL
sequence position: 25

UnificationXref319
type: UnificationXref
id: 5593973
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593973

SequenceSite304
type: SequenceSite
position status: EQUAL
sequence position: 558

UnificationXref312
type: UnificationXref
id: PFD0305c
db: UniProt

SequenceSite303
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref313
type: UnificationXref
id: 5593961
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593961

SequenceSite302
type: SequenceSite
position status: EQUAL
sequence position: 1243

UnificationXref314
type: UnificationXref
id: 5593962
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593962

SequenceSite301
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref315
type: UnificationXref
id: 5593963
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593963

SequenceSite310
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref320
type: UnificationXref
id: 5593974
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593974

SequenceSite311
type: SequenceSite
position status: EQUAL
sequence position: 698

UnificationXref322
type: UnificationXref
id: 5593977
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593977

UnificationXref321
type: UnificationXref
id: 5593208
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593208

Maintenance of Telomeres
type: Pathway
data source: Provenance1
pathway component: REACT 251478.1
evidence: Evidence609
xref: UnificationXref3889
xref: UnificationXref3890
xref: RelationshipXref547
pathway order: PathwayStep598
display name: Telomere Maintenance
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/9380723
type: PublicationXref
id: 9380723
author: Rock, KL
author: Goldberg, A
author: Akopian, T
author: Craiu, A
db: Pubmed
title: Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide
source: Proc Natl Acad Sci U S A 94:10850-5
year: 1997

UniProt:PFC0535w
type: ProteinReference
xref: UnificationXref3357
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/11920679
type: PublicationXref
id: 11920679
author: Fleck, Oliver
author: Kunz, Christophe
author: Marti, Thomas M
db: Pubmed
title: DNA mismatch repair and mutation avoidance pathways
source: J. Cell. Physiol. 191:28-41
year: 2002

http://identifiers.org/pubmed/19935667
type: PublicationXref
id: 19935667
author: Hall, RA
author: Ritter, SL
db: Pubmed
title: Fine-tuning of GPCR activity by receptor-interacting proteins
source: Nat Rev Mol Cell Biol 10:819-30
year: 2009

Translation
type: Pathway
data source: Provenance1
pathway component: Eukaryotic Translation Elongation
pathway component: SRP-dependent cotranslational protein targeting to membrane
pathway component: REACT 239461.1
pathway component: REACT 235015.1
evidence: Evidence856
xref: RelationshipXref630
xref: UnificationXref4920
xref: UnificationXref4919
pathway order: PathwayStep831
pathway order: PathwayStep820
pathway order: PathwayStep835
pathway order: PathwayStep816
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/23604073
type: PublicationXref
id: 23604073
author: Ablasser, A
author: Hopfner, KP
author: Deimling, Tobias
author: Hornung, V
author: Cavlar, Taner
db: Pubmed
title: Species-specific detection of the antiviral small-molecule compound CMA by STING
source: EMBO J. 32:1440-50
year: 2013

http://identifiers.org/pubmed/11988738
type: PublicationXref
id: 11988738
author: Lukas, J
author: Jackson, PK
author: Reimann, JD
author: Sorensen, CS
author: Hsu, JY
db: Pubmed
title: E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)
source: Nat Cell Biol 4:358-66
year: 2002

UnificationXref300
type: UnificationXref
id: 5593944
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593944

http://identifiers.org/pubmed/12626323
type: PublicationXref
id: 12626323
author: Jiang, G
author: Zhang, BB
db: Pubmed
title: Glucagon and regulation of glucose metabolism
source: Am J Physiol Endocrinol Metab 284:E671-8
year: 2003

http://identifiers.org/pubmed/19330724
type: PublicationXref
id: 19330724
author: Chua, JH
author: Armugam, A
author: Jeyaseelan, K
db: Pubmed
title: MicroRNAs: biogenesis, function and applications
source: Curr Opin Mol Ther 11:189-99
year: 2009

http://identifiers.org/pubmed/17223360
type: PublicationXref
id: 17223360
author: Yamane, H
author: Kim, KW
author: Wang, M
author: Busby, J
author: Zondlo, J
db: Pubmed
title: Expression, purification, and characterization of human acetyl-CoA carboxylase 2
source: Protein Expr Purif 53:16-23
year: 2007

SequenceSite338
type: SequenceSite
position status: EQUAL
sequence position: 1

Uroporphyrinogen I
type: SmallMoleculeReference
name: Uroporphyrinogen I [ChEBI:9904]
xref: UnificationXref2992

SequenceSite339
type: SequenceSite
position status: EQUAL
sequence position: 351

http://identifiers.org/pubmed/7565730
type: PublicationXref
id: 7565730
author: van Raaij, TM
author: Riese DJ, 2nd
author: Stern, DF
author: Plowman, GD
author: Andrews, GC
db: Pubmed
title: The cellular response to neuregulins is governed by complex interactions of the erbB receptor family
source: Mol Cell Biol 15:5770-6
year: 1995

SequenceSite334
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite335
type: SequenceSite
position status: EQUAL
sequence position: 308

SequenceSite336
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite337
type: SequenceSite
position status: EQUAL
sequence position: 349

http://identifiers.org/pubmed/7968268
type: PublicationXref
id: 7968268
author: Hatch, GM
author: Cao, SG
db: Pubmed
title: Stimulation of phosphatidylglycerolphosphate phosphatase activity by unsaturated fatty acids in rat heart
source: Lipids 29:475-80
year: 1994

DCT1 (NRAMP2) mediates divalent iron uptake across the apical membrane of enterocytes
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence18
conversion direction: LEFT_TO_RIGHT
xref: UnificationXref150
xref: UnificationXref149
left: SmallMolecule20
left: SmallMolecule32
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule25
right: SmallMolecule22

NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence17
conversion direction: LEFT_TO_RIGHT
xref: UnificationXref145
xref: UnificationXref144
participant stoichiometry: Stoichiometry6
participant stoichiometry: Stoichiometry5
left: SmallMolecule22
left: SmallMolecule23
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule31
right: SmallMolecule27

HMIT co-transports myo-inositol with a proton
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence15
conversion direction: LEFT_TO_RIGHT
xref: UnificationXref118
xref: UnificationXref117
left: SmallMolecule19
left: SmallMolecule20
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule21
right: SmallMolecule22

UniProt:PFL0900c
type: ProteinReference
xref: UnificationXref5474
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/1644792
type: PublicationXref
id: 1644792
author: Jhon, DY
author: Rhee, SG
author: Kriz, R
author: Knopf, J
author: Park, D
db: Pubmed
title: Cloning, sequencing, expression, and Gq-independent activation of phospholipase C-beta 2
source: J Biol Chem 267:16048-55
year: 1992

SequenceSite342
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite341
type: SequenceSite
position status: EQUAL
sequence position: 559

SequenceSite344
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite343
type: SequenceSite
position status: EQUAL
sequence position: 890

SequenceSite340
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/15326200
type: PublicationXref
id: 15326200
author: Sundareshan, S
author: Mazumdar, M
author: Misteli, T
db: Pubmed
title: Human chromokinesin KIF4A functions in chromosome condensation and segregation
source: J Cell Biol 166:613-20
year: 2004

SequenceSite349
type: SequenceSite
position status: EQUAL
sequence position: 427

SequenceSite347
type: SequenceSite
position status: EQUAL
sequence position: 488

SequenceSite348
type: SequenceSite
position status: EQUAL
sequence position: 35

SequenceSite345
type: SequenceSite
position status: EQUAL
sequence position: 896

SequenceSite346
type: SequenceSite
position status: EQUAL
sequence position: 1

Type III Na+/Pi cotransport
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence5
conversion direction: LEFT_TO_RIGHT
xref: UnificationXref67
xref: UnificationXref68
participant stoichiometry: Stoichiometry4
participant stoichiometry: Stoichiometry3
left: SmallMolecule13
left: SmallMolecule14
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule10
right: SmallMolecule15

alpha-D-Glucose + ATP => alpha-D-glucose 6-phosphate + ADP
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence8
conversion direction: LEFT_TO_RIGHT
EC number: 2.7.1.2
xref: UnificationXref85
xref: UnificationXref84
left: SmallMolecule16
left: SmallMolecule7
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule11
right: SmallMolecule17

glucokinase [nucleoplasm] => glucokinase [cytosol]
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence9
conversion direction: LEFT_TO_RIGHT
xref: UnificationXref89
xref: UnificationXref88
left: Protein10
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: Protein7

Glucose transport by class III GLUTs
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence13
conversion direction: LEFT_TO_RIGHT
xref: UnificationXref103
xref: UnificationXref102
left: SmallMolecule18
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule16

ABC7, mABC1 and mABC2 mediate heme transport
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence1
conversion direction: LEFT_TO_RIGHT
xref: UnificationXref27
xref: UnificationXref28
left: SmallMolecule1
left: SmallMolecule2
left: SmallMolecule3
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule4
right: SmallMolecule5
right: SmallMolecule6

MTABC3 transports porphyrin into mitochondria
type: BiochemicalReaction
data source: Provenance1
evidence: Evidence2
conversion direction: LEFT_TO_RIGHT
xref: UnificationXref47
xref: UnificationXref48
left: SmallMolecule9
left: SmallMolecule7
left: SmallMolecule8
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
right: SmallMolecule12
right: SmallMolecule10
right: SmallMolecule11

SequenceSite355
type: SequenceSite
position status: EQUAL
sequence position: 649

SequenceSite354
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite353
type: SequenceSite
position status: EQUAL
sequence position: 698

SequenceSite352
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite351
type: SequenceSite
position status: EQUAL
sequence position: 727

SequenceSite350
type: SequenceSite
position status: EQUAL
sequence position: 43

SequenceSite312
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite313
type: SequenceSite
position status: EQUAL
sequence position: 711

SequenceSite314
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite315
type: SequenceSite
position status: EQUAL
sequence position: 683

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFL0565w
data source: Provenance1
name: DNAJB9
name: PFL0565w
name: ERdj4
xref: UnificationXref5300
feature: FragmentFeature704
cellular location: GO_0005789
comment: Reactome DB_ID: 5596127
display name: MDG1

SequenceSite316
type: SequenceSite
position status: EQUAL
sequence position: 1

ARFGAP1
type: Protein
entity reference: PFL2140c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: PFL2140c
xref: UnificationXref5304
feature: FragmentFeature705
cellular location: GO_0005829
comment: Reactome DB_ID: 5594793
display name: GAP

SequenceSite317
type: SequenceSite
position status: EQUAL
sequence position: 697

SequenceSite318
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite319
type: SequenceSite
position status: EQUAL
sequence position: 279

Peptide chain elongation
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction416
pathway component: BiochemicalReaction417
pathway component: BiochemicalReaction413
pathway component: BiochemicalReaction414
pathway component: BiochemicalReaction415
evidence: Evidence848
xref: UnificationXref4889
xref: UnificationXref4890
pathway order: PathwayStep823
pathway order: PathwayStep826
pathway order: PathwayStep827
pathway order: PathwayStep824
pathway order: PathwayStep825
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/11242114
type: PublicationXref
id: 11242114
author: Brahmbhatt, SB
author: Hulme, DJ
author: Nicholson, GA
author: Dawkins, JL
author: Auer-Grumbach, M
db: Pubmed
title: Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit-1, cause hereditary sensory neuropathy type I
source: Nat Genet 27:309-12
year: 2001

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: MAL13P1.540
data source: Provenance1
name: HYOU1_HUMAN
name: MAL13P1.540
name: Hypoxia up-regulated protein 1
xref: UnificationXref5312
feature: FragmentFeature706
cellular location: GO_0005788
comment: Reactome DB_ID: 5596104
display name: HYOU1

PFI0930c
type: Protein
entity reference: PFI0930c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: TSYL2_HUMAN
name: Testis-specific Y-encoded-like protein 2
xref: UnificationXref5337
feature: FragmentFeature711
cellular location: GO_0005654
comment: Reactome DB_ID: 5596097
display name: TSPYL2

E3 ubiquitin-protein ligase synoviolin
type: Protein
entity reference: PF14_0215
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: PF14_0215
name: SYVN1_HUMAN
name: SYVN1(1-617)
xref: UnificationXref5331
feature: FragmentFeature710
cellular location: GO_0005789
comment: Reactome DB_ID: 5596110
display name: SYVN1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0423
data source: Provenance1
name: PF14_0423
name: EIF2AK3
xref: UnificationXref5349
feature: FragmentFeature713
cellular location: GO_0005789
comment: Reactome DB_ID: 5595195
display name: PERK

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF10_0126
data source: Provenance1
name: PF10_0126
name: WIPI1_HUMAN
name: WD repeat domain phosphoinositide-interacting protein 1
xref: UnificationXref5341
feature: FragmentFeature712
cellular location: GO_0000139
comment: Reactome DB_ID: 5596138
display name: WIPI1

Homologues of PDIA5
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5323
cellular location: GO_0005789
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5596121

SequenceSite320
type: SequenceSite
position status: EQUAL
sequence position: 1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF13_0280
data source: Provenance1
name: ERD23_HUMAN
name: ER lumen protein retaining receptor 3
name: PF13_0280
xref: UnificationXref5316
feature: FragmentFeature707
cellular location: GO_0005789
comment: Reactome DB_ID: 5596124
display name: KDELR3

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF11_0352
data source: Provenance1
name: Protein disulfide-isomerase A5
name: PF11_0352
name: PDIA5_HUMAN
xref: UnificationXref5322
feature: FragmentFeature709
cellular location: GO_0005789
comment: Reactome DB_ID: 5596120
display name: PDIA5

SequenceSite322
type: SequenceSite
position status: EQUAL
sequence position: 1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0694
data source: Provenance1
name: Protein disulfide-isomerase A5
name: PF14_0694
name: PDIA5_HUMAN
xref: UnificationXref5320
feature: FragmentFeature708
cellular location: GO_0005789
comment: Reactome DB_ID: 5596118
display name: PDIA5

SequenceSite321
type: SequenceSite
position status: EQUAL
sequence position: 296

SequenceSite325
type: SequenceSite
position status: EQUAL
sequence position: 314

SequenceSite326
type: SequenceSite
position status: EQUAL
sequence position: 1

Synthesis of pyrophosphates in the cytosol
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction107
pathway component: BiochemicalReaction106
evidence: Evidence222
xref: RelationshipXref170
xref: UnificationXref1285
xref: UnificationXref1286
pathway order: PathwayStep218
pathway order: PathwayStep219
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

SequenceSite323
type: SequenceSite
position status: EQUAL
sequence position: 270

SequenceSite324
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite329
type: SequenceSite
position status: EQUAL
sequence position: 265

phospho-p-S52-EIF2S1
type: Protein
entity reference: UniProt:PF07_0117
data source: Provenance1
xref: UnificationXref5353
feature: ModificationFeature61
feature: FragmentFeature714
cellular location: GO_0005829
comment: Reactome DB_ID: 5595200

SequenceSite327
type: SequenceSite
position status: EQUAL
sequence position: 299

SequenceSite328
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/11242102
type: PublicationXref
id: 11242102
author: Khanna, KK
db: Pubmed
title: DNA double-strand breaks: signaling, repair and the cancer connection.
source: Nat Genet 27:247-54
year: 2001

http://identifiers.org/pubmed/22118461
type: PublicationXref
id: 22118461
author: Desai, Arshad
author: Hombauer, Hans
author: Smith, Catherine E
author: Campbell, Christopher S
author: Kolodner, Richard D
db: Pubmed
title: Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates
source: Cell 147:1040-53
year: 2011

SequenceSite333
type: SequenceSite
position status: EQUAL
sequence position: 312

SequenceSite332
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite331
type: SequenceSite
position status: EQUAL
sequence position: 281

SequenceSite330
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/15795316
type: PublicationXref
id: 15795316
author: Liu, Wei
author: Lippincott-Schwartz, J
author: Duden, R
author: Phair, RD
db: Pubmed
title: ArfGAP1 dynamics and its role in COPI coat assembly on Golgi membranes of living cells
source: J Cell Biol 168:1053-63
year: 2005

SequenceSite392
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite393
type: SequenceSite
position status: EQUAL
sequence position: 369

SequenceSite394
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite395
type: SequenceSite
position status: EQUAL
sequence position: 406

SequenceSite396
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/16413920
type: PublicationXref
id: 16413920
author: Nimmerjahn, F
author: Ravetch, JV
db: Pubmed
title: Fcgamma receptors: old friends and new family members
source: Immunity 24:19-28
year: 2006

SequenceSite397
type: SequenceSite
position status: EQUAL
sequence position: 406

SequenceSite398
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite399
type: SequenceSite
position status: EQUAL
sequence position: 473

UnificationXref98
type: UnificationXref
id: PFB0210c
db: UniProt

UnificationXref97
type: UnificationXref
id: REACT_4078
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_4078.3

UnificationXref96
type: UnificationXref
id: 70115
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=70115

UnificationXref95
type: UnificationXref
id: REACT_261851
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_261851.1

SequenceSite390
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite391
type: SequenceSite
position status: EQUAL
sequence position: 367

UnificationXref99
type: UnificationXref
id: 5595354
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595354

UnificationXref90
type: UnificationXref
id: 5596868
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596868

UnificationXref93
type: UnificationXref
id: REACT_256642
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_256642.1

UnificationXref94
type: UnificationXref
id: 5596684
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596684

UnificationXref91
type: UnificationXref
id: REACT_237782
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_237782.1

http://identifiers.org/pubmed/6490615
type: PublicationXref
id: 6490615
author: Shimizu, T
author: Samuelsson, B
author: Rådmark, O
author: Jörnvall, H
db: Pubmed
title: Leukotriene A4 hydrolase in human leukocytes. Purification and properties
source: J Biol Chem 259:12339-45
year: 1984

UnificationXref92
type: UnificationXref
id: 5596683
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596683

SRP-dependent cotranslational protein targeting to membrane
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction410
pathway component: BiochemicalReaction409
pathway component: BiochemicalReaction408
evidence: Evidence840
xref: RelationshipXref619
xref: UnificationXref4793
xref: UnificationXref4794
pathway order: PathwayStep819
pathway order: PathwayStep818
pathway order: PathwayStep817
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

SequenceSite389
type: SequenceSite
position status: EQUAL
sequence position: 782

http://identifiers.org/pubmed/11779870
type: PublicationXref
id: 11779870
author: Tsurumi, T
author: Fujita, M
author: Kiyono, T
author: Nakamura, H
author: Ishimi, Y
db: Pubmed
title: Nuclear organization of DNA replication initiation proteins in mammalian cells.
source: J Biol Chem 277:10354-61
year: 2002

http://identifiers.org/pubmed/12205100
type: PublicationXref
id: 12205100
author: Van Komen, S
author: Sigurdsson, S
author: Petukhova, G
author: Sung, P
db: Pubmed
title: Homologous DNA pairing by human recombination factors Rad51 and Rad54
source: J Biol Chem 277:42790-4
year: 2002

SequenceSite383
type: SequenceSite
position status: EQUAL
sequence position: 409

SequenceSite384
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite381
type: SequenceSite
position status: EQUAL
sequence position: 416

SequenceSite382
type: SequenceSite
position status: EQUAL
sequence position: 378

http://identifiers.org/pubmed/9564029
type: PublicationXref
id: 9564029
author: Kushner, JP
author: Phillips, JD
author: Hill, CP
author: Whitby, FG
db: Pubmed
title: Crystal structure of human uroporphyrinogen decarboxylase
source: EMBO J 17:2463-71
year: 1998

http://identifiers.org/pubmed/3413114
type: PublicationXref
id: 3413114
author: Cram, LS
author: Wu, JR
author: Ratliff, RL
author: Buckingham, JM
author: Moyzis, RK
author: Jones, MD
author: Meyne, J
author: Deaven, LL
author: Dani, M
db: Pubmed
title: A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes
source: Proc Natl Acad Sci U S A 85:6622-6
year: 1988

SequenceSite387
type: SequenceSite
position status: EQUAL
sequence position: 806

SequenceSite388
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite385
type: SequenceSite
position status: EQUAL
sequence position: 377

SequenceSite386
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/16793762
type: PublicationXref
id: 16793762
author: Pewzner-Jung, Y
author: Ben-Dor, S
author: Futerman, AH
db: Pubmed
title: When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: Insights into the regulation of ceramide synthesis
source: J Biol Chem 281:25001-5
year: 2006

http://identifiers.org/pubmed/18202181
type: PublicationXref
id: 18202181
author: Hub, JS
author: de Groot, BL
db: Pubmed
title: Mechanism of selectivity in aquaporins and aquaglyceroporins
source: Proc Natl Acad Sci U S A 105:1198-203
year: 2008

http://identifiers.org/pubmed/4218100
type: PublicationXref
id: 4218100
author: Matalon, R
author: Brandt, IK
author: Dorfman, A
author: Justice, P
author: Arbogast, B
db: Pubmed
title: Morquio's syndrome: deficiency of a chondroitin sulfate N-acetylhexosamine sulfate sulfatase
source: Biochem Biophys Res Commun 61:759-65
year: 1974

SequenceSite380
type: SequenceSite
position status: EQUAL
sequence position: 1

Metabolism of nitric oxide
type: Pathway
data source: Provenance1
pathway component: REACT 192706.3
evidence: Evidence375
xref: RelationshipXref352
xref: UnificationXref2211
xref: UnificationXref2212
pathway order: PathwayStep371
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/7990965
type: PublicationXref
id: 7990965
author: Rasmussen, HH
author: Philippe, M
author: Drugeon, G
author: Celis, JE
author: Kress, M
author: Frolova, L
author: Cheperegin, S
author: Arman, I
author: Haenni, AL
author: Le, Goff X
db: Pubmed
title: A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor
source: Nature 372:701-3
year: 1994

SequenceSite379
type: SequenceSite
position status: EQUAL
sequence position: 416

SequenceSite378
type: SequenceSite
position status: EQUAL
sequence position: 1

Association of licensing factors with the pre-replicative complex
type: Pathway
data source: Provenance1
pathway component: TemplateReaction6
evidence: Evidence587
xref: UnificationXref3828
xref: UnificationXref3829
pathway order: PathwayStep576
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

SequenceSite374
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite375
type: SequenceSite
position status: EQUAL
sequence position: 389

SequenceSite376
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite377
type: SequenceSite
position status: EQUAL
sequence position: 851

SequenceSite370
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite371
type: SequenceSite
position status: EQUAL
sequence position: 452

SequenceSite372
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite373
type: SequenceSite
position status: EQUAL
sequence position: 386

UnificationXref79
type: UnificationXref
id: PFF1155w
db: UniProt

UnificationXref78
type: UnificationXref
id: REACT_3817
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3817.2

UnificationXref77
type: UnificationXref
id: 30537
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=30537

UnificationXref76
type: UnificationXref
id: CHEBI:17665
db: ChEBI

UnificationXref75
type: UnificationXref
id: REACT_2878
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2878.2

UnificationXref74
type: UnificationXref
id: 70113
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=70113

UnificationXref73
type: UnificationXref
id: CHEBI:17925
db: ChEBI

UnificationXref71
type: UnificationXref
id: 5596977
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596977

UnificationXref72
type: UnificationXref
id: REACT_251489
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_251489.1

UnificationXref70
type: UnificationXref
id: REACT_254964
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_254964.1

http://identifiers.org/pubmed/18403674
type: PublicationXref
id: 18403674
author: Steele, C
author: Mossman, BT
author: Dostert, C
author: Tschopp, J
author: Van Bruggen, R
author: Pétrilli, V
db: Pubmed
title: Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
source: Science 320:674-7
year: 2008

SequenceSite368
type: SequenceSite
position status: EQUAL
sequence position: 2

SequenceSite367
type: SequenceSite
position status: EQUAL
sequence position: 457

SequenceSite369
type: SequenceSite
position status: EQUAL
sequence position: 395

SequenceSite365
type: SequenceSite
position status: EQUAL
sequence position: 481

SequenceSite366
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite363
type: SequenceSite
position status: EQUAL
sequence position: 504

Advanced glycosylation endproduct receptor signaling
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction388
evidence: Evidence743
xref: UnificationXref4473
xref: UnificationXref4474
pathway order: PathwayStep724
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

SequenceSite364
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite361
type: SequenceSite
position status: EQUAL
sequence position: 318

SequenceSite362
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite360
type: SequenceSite
position status: EQUAL
sequence position: 1

UnificationXref89
type: UnificationXref
id: REACT_252807
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_252807.1

UnificationXref88
type: UnificationXref
id: 5594504
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594504

http://identifiers.org/pubmed/10529898
type: PublicationXref
id: 10529898
author: Wahli, W
author: Desvergne, B
db: Pubmed
title: Peroxisome proliferator-activated receptors: nuclear control of metabolism
source: Endocr Rev 20:649-88
year: 1999

UnificationXref85
type: UnificationXref
id: REACT_258179
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_258179.1

UnificationXref84
type: UnificationXref
id: 5593337
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593337

UnificationXref87
type: UnificationXref
id: 5594503
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594503

UnificationXref86
type: UnificationXref
id: GO:0005654
db: GENE ONTOLOGY

UnificationXref80
type: UnificationXref
id: 5593332
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593332

UniProt:PFF1130c
type: ProteinReference
xref: UnificationXref5798
organism: http://identifiers.org/taxonomy/5833

UnificationXref81
type: UnificationXref
id: 5593333
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593333

http://identifiers.org/pubmed/3208766
type: PublicationXref
id: 3208766
author: Day, IN
author: Fothergill, JE
author: McAleese, SM
author: Hinks, LJ
author: Dunbar, B
db: Pubmed
title: Complete amino acid sequence of the neurone-specific gamma isozyme of enolase (NSE) from human brain and comparison with the non-neuronal alpha form (NNE)
source: Eur J Biochem 178:413-7
year: 1988

UnificationXref82
type: UnificationXref
id: 5593334
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593334

UnificationXref83
type: UnificationXref
id: 5593335
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593335

http://identifiers.org/pubmed/20930137
type: PublicationXref
id: 20930137
author: Kull, FJ
author: Endow, SA
author: Liu, H
db: Pubmed
title: Kinesins at a glance
source: J Cell Sci 123:3420-4
year: 2010

SequenceSite359
type: SequenceSite
position status: EQUAL
sequence position: 310

SequenceSite358
type: SequenceSite
position status: EQUAL
sequence position: 1

SequenceSite357
type: SequenceSite
position status: EQUAL
sequence position: 419

SequenceSite356
type: SequenceSite
position status: EQUAL
sequence position: 1

http://identifiers.org/pubmed/19540337
type: PublicationXref
id: 19540337
author: Masson, K
author: Rönnstrand, L
db: Pubmed
title: Oncogenic signaling from the hematopoietic growth factor receptors c-Kit and Flt3
source: Cell Signal 21:1717-26
year: 2009

http://identifiers.org/pubmed/9083101
type: PublicationXref
id: 9083101
author: Hosaka, K
author: Nikawa, J
author: Nakashima, A
db: Pubmed
title: Cloning of a human cDNA for CTP-phosphoethanolamine cytidylyltransferase by complementation in vivo of a yeast mutant
source: J Biol Chem 272:9567-72
year: 1997

PI Metabolism
type: Pathway
data source: Provenance1
pathway component: REACT 226265.2
pathway component: REACT 208421.2
pathway component: REACT 192724.3
evidence: Evidence324
xref: UnificationXref1880
xref: UnificationXref1881
xref: RelationshipXref306
pathway order: PathwayStep308
pathway order: PathwayStep312
pathway order: PathwayStep321
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4690
type: UnificationXref
id: 72595
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=72595

UnificationXref4692
type: UnificationXref
id: 5593702
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593702

UnificationXref4691
type: UnificationXref
id: REACT_3670
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3670.1

UnificationXref4697
type: UnificationXref
id: REACT_206648
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_206648.2

UnificationXref4698
type: UnificationXref
id: 5593694
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593694

UnificationXref4699
type: UnificationXref
id: 72617
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=72617

http://identifiers.org/pubmed/20713702
type: PublicationXref
id: 20713702
author: Sun, Minghao
author: Hart, Jonathan R
author: Hofmann, Bianca T
author: Hillmann, Petra
author: Vogt, Peter K
db: Pubmed
title: Cancer-derived mutations in the regulatory subunit p85alpha of phosphoinositide 3-kinase function through the catalytic subunit p110alpha
source: Proc. Natl. Acad. Sci. U.S.A. 107:15547-52
year: 2010

UnificationXref4693
type: UnificationXref
id: 5593703
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593703

CHEBI:71956
type: SmallMoleculeReference
name: CHEBI:71956 [ChEBI:71956]
xref: UnificationXref530

UnificationXref4694
type: UnificationXref
id: 5593704
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593704

UnificationXref4695
type: UnificationXref
id: REACT_203964
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_203964.2

UnificationXref4696
type: UnificationXref
id: 5596715
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596715

di-retinoid-pyridinium-ethanolamine
type: SmallMoleculeReference
name: di-retinoid-pyridinium-ethanolamine [ChEBI:71980]
name: A2E
xref: UnificationXref615

UnificationXref4681
type: UnificationXref
id: 5593706
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593706

UnificationXref4680
type: UnificationXref
id: REACT_253832
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253832.1

UnificationXref4684
type: UnificationXref
id: 5593828
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593828

UnificationXref4685
type: UnificationXref
id: 5593829
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593829

UnificationXref4682
type: UnificationXref
id: REACT_254237
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_254237.1

UnificationXref4683
type: UnificationXref
id: 5593707
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593707

UnificationXref4688
type: UnificationXref
id: REACT_255830
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_255830.1

UnificationXref4689
type: UnificationXref
id: 5593686
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593686

UnificationXref4686
type: UnificationXref
id: REACT_258067
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_258067.1

UnificationXref4687
type: UnificationXref
id: 5596716
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596716

http://identifiers.org/pubmed/10958654
type: PublicationXref
id: 10958654
author: Vincent, MF
author: Marie, S
author: Van den Berghe, G
author: Race, V
db: Pubmed
title: Clinical, biochemical and molecular genetic correlations in adenylosuccinate lyase deficiency
source: Hum Mol Genet 9:2159-2165
year: 2000

http://identifiers.org/pubmed/6338048
type: PublicationXref
id: 6338048
author: McLaren, KM
db: Pubmed
title: Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets
source: J Clin Pathol 36:197-9
year: 1983

UnificationXref4670
type: UnificationXref
id: REACT_192010
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192010.3

UnificationXref4671
type: UnificationXref
id: 5596824
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596824

UnificationXref4672
type: UnificationXref
id: REACT_253622
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253622.1

UnificationXref4673
type: UnificationXref
id: 5596737
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596737

http://identifiers.org/pubmed/19946895
type: PublicationXref
id: 19946895
author: Albers, E
db: Pubmed
title: Metabolic characteristics and importance of the universal methionine salvage pathway recycling methionine from 5'-methylthioadenosine
source: IUBMB Life 61:1132-42
year: 2009

UnificationXref4674
type: UnificationXref
id: REACT_191610
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_191610.3

UnificationXref4675
type: UnificationXref
id: 5593827
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593827

UnificationXref4676
type: UnificationXref
id: REACT_248427
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_248427.1

UnificationXref4677
type: UnificationXref
id: 5596719
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596719

UnificationXref4678
type: UnificationXref
id: REACT_258018
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_258018.1

UnificationXref4679
type: UnificationXref
id: 5593705
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593705

http://identifiers.org/pubmed/12151002
type: PublicationXref
id: 12151002
author: Paiement, J
author: Desjardins, M
author: Bergeron, JJ
author: Cameron, PH
author: Duclos, S
author: Chevet, E
author: Gagnon, E
author: Steele-Mortimer, O
author: Rondeau, C
db: Pubmed
title: Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages
source: Cell 110:119-31
year: 2002

http://identifiers.org/pubmed/17517897
type: PublicationXref
id: 17517897
author: Wilson, GM
author: Toth, EA
author: Willis, CD
author: Ballin, JD
author: Brewer, BY
author: Fialcowitz-White, EJ
db: Pubmed
title: Specific protein domains mediate cooperative assembly of HuR oligomers on AU-rich mRNA-destabilizing sequences
source: J Biol Chem 282:20948-59
year: 2007

UnificationXref4669
type: UnificationXref
id: 5596798
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596798

UnificationXref4668
type: UnificationXref
id: REACT_192012
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192012.3

UnificationXref4665
type: UnificationXref
id: 5596802
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596802

UnificationXref4664
type: UnificationXref
id: REACT_240431
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_240431.1

UnificationXref4667
type: UnificationXref
id: 5596797
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596797

UnificationXref4666
type: UnificationXref
id: REACT_192034
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_192034.3

UnificationXref4661
type: UnificationXref
id: 5597104
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597104

L-cysteine persulfide
type: SequenceModificationVocabulary
xref: UnificationXref1124

UnificationXref4660
type: UnificationXref
id: REACT_193028
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_193028.3

UnificationXref4663
type: UnificationXref
id: 5596796
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596796

UnificationXref4662
type: UnificationXref
id: REACT_193030
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_193030.3

http://identifiers.org/pubmed/19383790
type: PublicationXref
id: 19383790
author: Robbins, RA
author: Chorny, I
author: Miercke, LJ
author: Yeh, R
author: Ho, JD
author: Stroud, RM
author: Harries, WE
author: Sandstrom, A
db: Pubmed
title: Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance
source: Proc Natl Acad Sci U S A 106:7437-42
year: 2009

UnificationXref4659
type: UnificationXref
id: 5597103
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597103

UnificationXref4658
type: UnificationXref
id: REACT_193021
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_193021.3

UnificationXref4657
type: UnificationXref
id: 5597102
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5597102

UnificationXref4656
type: UnificationXref
id: REACT_251272
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_251272.1

UnificationXref4655
type: UnificationXref
id: 5596565
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596565

UnificationXref4654
type: UnificationXref
id: REACT_235703
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_235703.1

UnificationXref4653
type: UnificationXref
id: 5596736
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596736

Acyl chain remodelling of PC
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction155
pathway component: BiochemicalReaction154
evidence: Evidence296
xref: UnificationXref1736
xref: UnificationXref1735
xref: RelationshipXref270
pathway order: PathwayStep293
pathway order: PathwayStep292
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4652
type: UnificationXref
id: REACT_230516
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_230516.1

UnificationXref4651
type: UnificationXref
id: 5596818
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596818

UnificationXref4650
type: UnificationXref
id: REACT_253603
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253603.1

http://identifiers.org/pubmed/11347887
type: PublicationXref
id: 11347887
author: Hou, YM
author: King, MP
author: Davidson, E
author: Vitseva, O
author: Caffarella, J
db: Pubmed
title: Isolation of two cDNAs encoding functional human cytoplasmic cysteinyl-tRNA synthetase
source: Biol Chem 382:399-406
year: 2001

http://identifiers.org/pubmed/10484769
type: PublicationXref
id: 10484769
author: Wilson, A
author: Rosenblatt, DS
author: Gravel, R A
author: Leclerc, D
db: Pubmed
title: Molecular basis for methionine synthase reductase deficiency in patients belonging to the cblE complementation group of disorders in folate/cobalamin metabolism
source: Hum. Mol. Genet. 8:2009-16
year: 1999

UnificationXref4647
type: UnificationXref
id: 5596927
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596927

UnificationXref4646
type: UnificationXref
id: REACT_230158
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_230158.1

UnificationXref4649
type: UnificationXref
id: 5596735
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596735

UniProt:PFD1035w
type: ProteinReference
xref: UnificationXref1418
organism: http://identifiers.org/taxonomy/5833

UnificationXref4648
type: UnificationXref
id: REACT_255120
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_255120.1

UnificationXref4641
type: UnificationXref
id: 5594826
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594826

UnificationXref4640
type: UnificationXref
id: REACT_251600
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_251600.1

UnificationXref4643
type: UnificationXref
id: 5594830
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594830

UnificationXref3197
type: UnificationXref
id: 5596952
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596952

Eukaryotic Translation Elongation
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction418
pathway component: BiochemicalReaction419
pathway component: BiochemicalReaction412
pathway component: BiochemicalReaction411
pathway component: Peptide chain elongation
evidence: Evidence851
xref: RelationshipXref628
xref: UnificationXref4903
xref: UnificationXref4904
pathway order: PathwayStep822
pathway order: PathwayStep821
pathway order: PathwayStep830
pathway order: PathwayStep828
pathway order: PathwayStep829
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4642
type: UnificationXref
id: 5594829
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594829

UnificationXref3198
type: UnificationXref
id: REACT_248978
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_248978.1

http://identifiers.org/pubmed/20713735
type: PublicationXref
id: 20713735
author: Kadyrov, Farid A
author: Modrich, Paul
author: Iyer, Ravi R
author: Dzantiev, Leonid
author: Constantin, Nicoleta
author: Pluciennik, Anna
db: Pubmed
title: PCNA function in the activation and strand direction of MutL? endonuclease in mismatch repair
source: Proc. Natl. Acad. Sci. U.S.A. 107:16066-71
year: 2010

UnificationXref4645
type: UnificationXref
id: 5594832
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594832

UnificationXref3199
type: UnificationXref
id: 5596848
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596848

http://identifiers.org/pubmed/10413847
type: PublicationXref
id: 10413847
author: Bläker, M
author: de Weerth, A
author: von Schrenck, T
db: Pubmed
title: [Receptors for cholecystokinin and gastrin]
source: Z Gastroenterol 37:389-401
year: 1999

UnificationXref4644
type: UnificationXref
id: 5594831
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594831

UnificationXref3194
type: UnificationXref
id: 5594992
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594992

UnificationXref3193
type: UnificationXref
id: 5594991
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594991

UnificationXref3196
type: UnificationXref
id: REACT_248821
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_248821.1

UnificationXref3195
type: UnificationXref
id: 5594993
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594993

UnificationXref3190
type: UnificationXref
id: 5596951
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596951

UnificationXref3192
type: UnificationXref
id: PF10_0368
db: UniProt

UnificationXref3191
type: UnificationXref
id: REACT_242435
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_242435.1

UnificationXref4638
type: UnificationXref
id: REACT_250242
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_250242.1

UnificationXref4637
type: UnificationXref
id: 5596733
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596733

UnificationXref4636
type: UnificationXref
id: REACT_235611
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_235611.1

Removal of licensing factors from origins
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction321
pathway component: REACT 236500.1
pathway component: REACT 263437.1
evidence: Evidence588
xref: UnificationXref3830
xref: UnificationXref3831
pathway order: PathwayStep560
pathway order: PathwayStep555
pathway order: PathwayStep559
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4635
type: UnificationXref
id: 5596732
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596732

UnificationXref4639
type: UnificationXref
id: 5596734
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596734

UnificationXref4630
type: UnificationXref
id: REACT_245238
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_245238.1

ER to Golgi Transport
type: Pathway
data source: Provenance1
pathway component: REACT 244496.1
evidence: Evidence896
xref: UnificationXref5205
xref: RelationshipXref675
xref: UnificationXref5204
pathway order: PathwayStep875
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4634
type: UnificationXref
id: REACT_250746
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_250746.1

UnificationXref3188
type: UnificationXref
id: 5596950
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596950

UnificationXref4633
type: UnificationXref
id: 5596975
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596975

UnificationXref3189
type: UnificationXref
id: REACT_253140
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253140.1

UnificationXref4632
type: UnificationXref
id: REACT_249427
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_249427.1

UnificationXref3186
type: UnificationXref
id: 5594975
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594975

UnificationXref4631
type: UnificationXref
id: 5596974
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596974

UnificationXref3187
type: UnificationXref
id: REACT_256086
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_256086.1

UnificationXref3185
type: UnificationXref
id: 5594974
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594974

UnificationXref3184
type: UnificationXref
id: 5594973
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594973

UnificationXref3183
type: UnificationXref
id: 5594972
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594972

UnificationXref3182
type: UnificationXref
id: 5594971
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594971

http://identifiers.org/pubmed/19196647
type: PublicationXref
id: 19196647
author: De Camilli, Pietro
author: McCrea, HJ
db: Pubmed
title: Mutations in phosphoinositide metabolizing enzymes and human disease
source: Physiology (Bethesda) 24:8-16
year: 2009

NCAM signaling for neurite out-growth
type: Pathway
data source: Provenance1
pathway component: REACT 238671.1
evidence: Evidence617
xref: UnificationXref3914
xref: UnificationXref3915
pathway order: PathwayStep70
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref3181
type: UnificationXref
id: MAL8P1.72
db: UniProt

UnificationXref3180
type: UnificationXref
id: REACT_3913
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3913.3

UniProt:PFL0565w
type: ProteinReference
xref: UnificationXref5299
organism: http://identifiers.org/taxonomy/5833

UnificationXref4620
type: UnificationXref
id: REACT_234077
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_234077.1

UnificationXref4621
type: UnificationXref
id: 5596751
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596751

UnificationXref4622
type: UnificationXref
id: REACT_246360
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_246360.1

Sulfur amino acid metabolism
type: Pathway
data source: Provenance1
pathway component: Methionine salvage pathway
pathway component: BiochemicalReaction269
pathway component: BiochemicalReaction270
evidence: Evidence465
xref: UnificationXref2937
xref: UnificationXref2936
xref: RelationshipXref471
pathway order: PathwayStep458
pathway order: PathwayStep461
pathway order: PathwayStep460
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4623
type: UnificationXref
id: 5596752
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596752

UnificationXref4628
type: UnificationXref
id: REACT_231787
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_231787.1

UnificationXref4629
type: UnificationXref
id: 5596821
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596821

UnificationXref4624
type: UnificationXref
id: REACT_254847
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_254847.1

UnificationXref4625
type: UnificationXref
id: 5596820
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596820

UnificationXref4626
type: UnificationXref
id: REACT_230858
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_230858.1

http://identifiers.org/pubmed/13211603
type: PublicationXref
id: 13211603
author: Joklik, WK
author: Berg, P
db: Pubmed
title: Enzymatic phosphorylation of nucleoside diphosphates
source: J Biol Chem 210:657-672
year: 1954

UnificationXref4627
type: UnificationXref
id: 5596919
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596919

UnificationXref4611
type: UnificationXref
id: 5596766
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596766

UnificationXref4612
type: UnificationXref
id: REACT_244655
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_244655.1

PERK regulates gene expression
type: Pathway
data source: Provenance1
pathway component: ATF4 activates genes
pathway component: BiochemicalReaction457
pathway component: BiochemicalReaction456
evidence: Evidence942
xref: UnificationXref5361
xref: UnificationXref5360
xref: RelationshipXref683
pathway order: PathwayStep919
pathway order: PathwayStep918
pathway order: PathwayStep921
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4610
type: UnificationXref
id: REACT_261775
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_261775.1

UnificationXref4619
type: UnificationXref
id: 5596920
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596920

UnificationXref4617
type: UnificationXref
id: 5596823
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596823

UnificationXref4618
type: UnificationXref
id: REACT_254607
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_254607.1

UnificationXref4615
type: UnificationXref
id: 5596819
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596819

UnificationXref4616
type: UnificationXref
id: REACT_253156
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253156.1

http://identifiers.org/pubmed/9630229
type: PublicationXref
id: 9630229
author: Vainberg, IE
author: Klein, HL
author: Vandekerckhove, J
author: Rommelaere, H
author: Cowan, NJ
author: Lewis, SA
author: Ampe, C
db: Pubmed
title: Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin
source: Cell 93:863-73
year: 1998

UnificationXref4613
type: UnificationXref
id: 5596822
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596822

UnificationXref4614
type: UnificationXref
id: REACT_256371
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_256371.1

http://identifiers.org/pubmed/21029861
type: PublicationXref
id: 21029861
author: Hogg, JR
author: Goff, SP
db: Pubmed
title: Upf1 senses 3'UTR length to potentiate mRNA decay
source: Cell 143:379-89
year: 2010

http://identifiers.org/pubmed/7493035
type: PublicationXref
id: 7493035
author: Morris, CP
author: Hopwood, JJ
author: Blanch, L
author: Guo, XH
author: Sutherland, GR
author: Freeman, C
author: Baker, E
author: Orsborn, A
author: Scott, HS
db: Pubmed
title: Cloning of the sulphamidase gene and identification of mutations in Sanfilippo A syndrome
source: Nat Genet 11:465-7
year: 1995

http://identifiers.org/pubmed/11278511
type: PublicationXref
id: 11278511
author: Ding, WC
author: Berger, SH
author: Lebioda, L
author: Koli, S
author: Minor, W
author: Dunlap, RB
author: Phan, J
author: Steadman, DJ
db: Pubmed
title: Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors
source: J Biol Chem 276:14170-7
year: 2001

UnificationXref4600
type: UnificationXref
id: REACT_242794
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_242794.1

UnificationXref4601
type: UnificationXref
id: 5596742
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596742

UnificationXref4602
type: UnificationXref
id: REACT_258729
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_258729.1

UnificationXref4603
type: UnificationXref
id: 5596743
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596743

UnificationXref4604
type: UnificationXref
id: REACT_236513
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_236513.1

UnificationXref4605
type: UnificationXref
id: 5596931
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596931

http://identifiers.org/pubmed/59727
type: PublicationXref
id: 59727
author: Nachman, RL
author: Harpel, PC
db: Pubmed
title: Platelet alpha2-macroglobulin and alpha1-antitrypsin
source: J Biol Chem 251:4512-21
year: 1976

UnificationXref4606
type: UnificationXref
id: REACT_253030
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253030.1

UnificationXref4607
type: UnificationXref
id: 5596764
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596764

UnificationXref4608
type: UnificationXref
id: REACT_240876
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_240876.1

UnificationXref4609
type: UnificationXref
id: 5596765
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596765

http://identifiers.org/pubmed/10625641
type: PublicationXref
id: 10625641
author: Lopez-Jimenez, M
author: Ramesh, B
author: Srai, SK
author: Dedes, M
author: Williams, M
author: Leggett, A
author: Sharp, P
author: Tandy, S
db: Pubmed
title: Nramp2 expression is associated with pH-dependent iron uptake across the apical membrane of human intestinal Caco-2 cells
source: J Biol Chem 275:1023-9
year: 2000

http://identifiers.org/pubmed/8617223
type: PublicationXref
id: 8617223
author: Cole, TB
author: Findley, SD
author: Palmiter, RD
db: Pubmed
title: ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration
source: EMBO J 15:1784-91
year: 1996

UnificationXref291
type: UnificationXref
id: 5593947
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593947

UnificationXref292
type: UnificationXref
id: PF14_0615
db: UniProt

UnificationXref290
type: UnificationXref
id: MAL13P1.271
db: UniProt

UnificationXref299
type: UnificationXref
id: 5593943
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593943

http://identifiers.org/pubmed/16483568
type: PublicationXref
id: 16483568
author: Da Silva, CA
author: Frossard, N
author: Reber, L
db: Pubmed
title: Stem cell factor and its receptor c-Kit as targets for inflammatory diseases
source: Eur J Pharmacol 533:327-40
year: 2006

UnificationXref297
type: UnificationXref
id: 5593941
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593941

http://identifiers.org/pubmed/21781017
type: PublicationXref
id: 21781017
author: Pulimeno, P
author: Stutz, J
author: Spadaro, D
author: Schneider, Y
author: Citi, S
db: Pubmed
title: Regulation of small GTPases at epithelial cell-cell junctions
source: Mol Membr Biol
year: 2011

UnificationXref298
type: UnificationXref
id: 5593942
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593942

UnificationXref295
type: UnificationXref
id: 5593954
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593954

UnificationXref296
type: UnificationXref
id: PF08_0113
db: UniProt

UnificationXref293
type: UnificationXref
id: 5593952
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593952

UnificationXref294
type: UnificationXref
id: 5593953
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593953

http://identifiers.org/pubmed/16391004
type: PublicationXref
id: 16391004
author: Osborne, HB
author: Barreau, C
author: Paillard, L
db: Pubmed
title: AU-rich elements and associated factors: are there unifying principles?
source: Nucleic Acids Res 33:7138-50
year: 2005

UnificationXref490
type: UnificationXref
id: 5594759
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594759

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0038
data source: Provenance1
name: Cytochrome c
name: PF14_0038
xref: UnificationXref5821
feature: FragmentFeature782
cellular location: GO_0005743
comment: Reactome DB_ID: 5594435
display name: CYCS

UnificationXref492
type: UnificationXref
id: 5596332
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596332

http://identifiers.org/pubmed/10659855
type: PublicationXref
id: 10659855
author: Dever, TE
author: Lee, JH
author: Pestova, TV
author: Choi, SK
author: Lomakin, IB
author: Hellen, CU
db: Pubmed
title: The joining of ribosomal subunits in eukaryotes requires eIF5B.
source: Nature 403:332-5
year: 2000

Homologues of PRDX1
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5835
cellular location: GO_0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5596510

UnificationXref491
type: UnificationXref
id: 5594760
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594760

http://identifiers.org/pubmed/13115431
type: PublicationXref
id: 13115431
author: Lieberman, I
author: Kornberg, A
db: Pubmed
title: Enzymic synthesis and breakdown of a pyrimidine, orotic acid. I. Dihydro-orotic dehydrogenase
source: Biochim Biophys Acta 12:223-234
year: 1953

PF08_0071
type: Protein
entity reference: PF08_0071
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: SODM_HUMAN
name: Superoxide dismutase [Mn], mitochondrial ecNumber1.15.1.1/ecNumber
xref: UnificationXref5801
feature: FragmentFeature780
cellular location: GO_0005759
comment: Reactome DB_ID: 5596486
display name: SOD2

UnificationXref494
type: UnificationXref
id: PFC0525c
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0192
data source: Provenance1
name: GSR isoform 1
name: Glutathione reductase, mitochondrial
name: PF14_0192
name: GSHR_HUMAN
xref: UnificationXref5811
feature: FragmentFeature781
cellular location: GO_0005759
comment: Reactome DB_ID: 5596496
display name: GSR-1

UnificationXref493
type: UnificationXref
id: REACT_241988
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_241988.1

Homologues of SOD2
type: Protein
data source: Provenance1
member physical entity: PF08_0071
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5802
cellular location: GO_0005759
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5596487

UnificationXref496
type: UnificationXref
id: 5594744
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594744

http://identifiers.org/pubmed/16564093
type: PublicationXref
id: 16564093
author: Jacobsson, A
author: Jakobsson, A
author: Westerberg, R
db: Pubmed
title: Fatty acid elongases in mammals: their regulation and roles in metabolism
source: Prog Lipid Res 45:237-49
year: 2006

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFF1130c
data source: Provenance1
name: SODM_HUMAN
name: PFF1130c
name: Superoxide dismutase [Mn], mitochondrial ecNumber1.15.1.1/ecNumber
xref: UnificationXref5799
feature: FragmentFeature779
cellular location: GO_0005759
comment: Reactome DB_ID: 5596484
display name: SOD2

UnificationXref495
type: UnificationXref
id: 5594743
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594743

http://identifiers.org/pubmed/5789664
type: PublicationXref
id: 5789664
author: Thomas, DP
author: Niewiarowski, S
db: Pubmed
title: Platelet factor 4 and adenosine diphosphate release during human platelet aggregation
source: Nature 222:1269-70
year: 1969

UnificationXref498
type: UnificationXref
id: 5594747
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594747

UnificationXref497
type: UnificationXref
id: 5594745
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594745

UnificationXref488
type: UnificationXref
id: 5594734
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594734

UnificationXref489
type: UnificationXref
id: 5594758
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594758

UnificationXref3220
type: UnificationXref
id: 5596843
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596843

UnificationXref3221
type: UnificationXref
id: REACT_259978
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_259978.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFC0710w.1
data source: Provenance1
name: PFC0710w.1
name: Inorganic pyrophosphatase 2, mitochondrial
name: pyrophosphatase (inorganic) 2
xref: UnificationXref5768
feature: FragmentFeature778
cellular location: GO_0005759
comment: Reactome DB_ID: 5595504
display name: PPA2

UnificationXref3222
type: UnificationXref
id: CHEBI:17815
db: ChEBI

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFC0710w.2
data source: Provenance1
name: PFC0710w.2
name: Inorganic pyrophosphatase 2, mitochondrial
name: pyrophosphatase (inorganic) 2
xref: UnificationXref5767
feature: FragmentFeature777
cellular location: GO_0005759
comment: Reactome DB_ID: 5595503
display name: PPA2

UnificationXref3223
type: UnificationXref
id: 114519
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=114519

Homologues of PPA2
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5769
cellular location: GO_0005759
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5595505

UnificationXref3224
type: UnificationXref
id: REACT_3927
db: Reactome
id version: 5
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_3927.5

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0589
data source: Provenance1
name: Valyl-tRNA synthetase 2
name: PF14_0589
xref: UnificationXref5764
feature: FragmentFeature776
cellular location: GO_0005759
comment: Reactome DB_ID: 5595142
display name: VARS2

UnificationXref3225
type: UnificationXref
id: 5594344
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594344

PF11_0181
type: Protein
entity reference: PF11_0181
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Tyrosyl-tRNA synthetase 2
xref: UnificationXref5754
feature: FragmentFeature775
cellular location: GO_0005759
comment: Reactome DB_ID: 5595131
display name: YARS2

UnificationXref3226
type: UnificationXref
id: 5594346
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594346

UnificationXref3227
type: UnificationXref
id: REACT_242610
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_242610.1

UniProt:PF10_0057
type: ProteinReference
xref: UnificationXref4008
organism: http://identifiers.org/taxonomy/5833

UnificationXref3228
type: UnificationXref
id: 5596852
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596852

http://identifiers.org/pubmed/20188572
type: PublicationXref
id: 20188572
author: von Lintig, Johannes
author: Palczewski, Krzysztof
author: Kiser, Philip D
author: Golczak, Marcin
db: Pubmed
title: The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision
source: Trends Biochem. Sci. 35:400-10
year: 2010

UnificationXref3229
type: UnificationXref
id: REACT_235909
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_235909.1

UniProt:PF10_0053
type: ProteinReference
xref: UnificationXref5696
organism: http://identifiers.org/taxonomy/5833

UniProt:PFI1485c
type: ProteinReference
xref: UnificationXref3274
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/12767043
type: PublicationXref
id: 12767043
author: Neri, LM
author: Tabellini, G
author: Borgatti, P
author: Martelli, AM
author: Capitani, S
author: Bellacosa, A
db: Pubmed
title: Threonine 308 phosphorylated form of Akt translocates to the nucleus of PC12 cells under nerve growth factor stimulation and associates with the nuclear matrix protein nucleolin
source: J Cell Physiol 196:79-88
year: 2003

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0277
data source: Provenance1
name: PF14_0277
name: Coatomer beta subunit
xref: UnificationXref5861
feature: FragmentFeature789
cellular location: GO_0005829
comment: Reactome DB_ID: 5594777
display name: COPB1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFD0745c
data source: Provenance1
name: Coatomer zeta-1 subunit
name: PFD0745c
xref: UnificationXref5863
feature: FragmentFeature790
cellular location: GO_0005829
comment: Reactome DB_ID: 5594785
display name: COPZ1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF11_0463
data source: Provenance1
name: Coatomer gamma subunit
name: PF11_0463
xref: UnificationXref5865
feature: FragmentFeature791
cellular location: GO_0005829
comment: Reactome DB_ID: 5594783
display name: COPG1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF11_0359
data source: Provenance1
name: Coatomer delta subunit
name: PF11_0359
xref: UnificationXref5867
feature: FragmentFeature792
cellular location: GO_0005829
comment: Reactome DB_ID: 5594781
display name: ARCN1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL0725w
data source: Provenance1
name: Peroxiredoxin-2 ecNumber1.11.1.15/ecNumber
name: PFL0725w
name: PRDX2_HUMAN
xref: UnificationXref5838
feature: FragmentFeature786
cellular location: GO_0005829
comment: Reactome DB_ID: 5596513
display name: PRDX2

http://identifiers.org/pubmed/22952392
type: PublicationXref
id: 22952392
author: Nusse, Roel
author: Willert, Karl
db: Pubmed
title: Wnt proteins
source: Cold Spring Harb Perspect Biol 4:a007864
year: 2012

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: MAL7P1.159
data source: Provenance1
name: PRDX5_HUMAN
name: Peroxiredoxin-5, mitochondrial ecNumber1.11.1.15/ecNumber
name: MAL7P1.159
xref: UnificationXref5842
feature: FragmentFeature787
cellular location: GO_0005829
comment: Reactome DB_ID: 5596517
display name: PRDX5

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFF0330w
data source: Provenance1
name: Coatomer alpha subunit
name: PFF0330w
xref: UnificationXref5859
feature: FragmentFeature788
cellular location: GO_0005829
comment: Reactome DB_ID: 5594775
display name: COPA

S-(glycyl)-L-cysteine (Cys-Gly)
type: SequenceModificationVocabulary
xref: UnificationXref5235

UnificationXref3232
type: UnificationXref
id: REACT_24220
db: Reactome
id version: 2
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_24220.2

UnificationXref3233
type: UnificationXref
id: PF14_0346
db: UniProt

UnificationXref499
type: UnificationXref
id: 5594749
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594749

UnificationXref3230
type: UnificationXref
id: CHEBI:16356
db: ChEBI

UnificationXref3231
type: UnificationXref
id: 30991
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=30991

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL0725w
data source: Provenance1
name: PRDX1_HUMAN
name: Peroxiredoxin-1 ecNumber1.11.1.15/ecNumber
name: PFL0725w
xref: UnificationXref5834
feature: FragmentFeature784
cellular location: GO_0005829
comment: Reactome DB_ID: 5596509
display name: PRDX1

UnificationXref3236
type: UnificationXref
id: 5595259
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595259

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0368
data source: Provenance1
name: PRDX1_HUMAN
name: Peroxiredoxin-1 ecNumber1.11.1.15/ecNumber
name: PF14_0368
xref: UnificationXref5832
feature: FragmentFeature783
cellular location: GO_0005829
comment: Reactome DB_ID: 5596507
display name: PRDX1

UnificationXref3237
type: UnificationXref
id: 5595260
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595260

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0368
data source: Provenance1
name: Peroxiredoxin-2 ecNumber1.11.1.15/ecNumber
name: PF14_0368
name: PRDX2_HUMAN
xref: UnificationXref5837
feature: FragmentFeature785
cellular location: GO_0005829
comment: Reactome DB_ID: 5596512
display name: PRDX2

UnificationXref3234
type: UnificationXref
id: 5595257
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595257

Homologues of PRDX2
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5839
cellular location: GO_0005829
comment: Converted from EntitySet in Reactome
comment: Reactome DB_ID: 5596514

UnificationXref3235
type: UnificationXref
id: 5595258
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595258

UnificationXref4807
type: UnificationXref
id: CHEBI:18366
db: ChEBI

UnificationXref4806
type: UnificationXref
id: REACT_17687
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_17687.1

PLC-gamma1 signalling
type: Pathway
data source: Provenance1
pathway component: REACT 259160.1
evidence: Evidence779
xref: UnificationXref4594
xref: RelationshipXref609
xref: UnificationXref4593
pathway order: PathwayStep66
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4805
type: UnificationXref
id: 379700
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379700

UnificationXref3238
type: UnificationXref
id: 5595261
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595261

UnificationXref4804
type: UnificationXref
id: CHEBI:17732
db: ChEBI

UnificationXref3239
type: UnificationXref
id: REACT_242510
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_242510.1

UniProt:PF10_0043
type: ProteinReference
xref: UnificationXref3420
organism: http://identifiers.org/taxonomy/5833

UnificationXref4803
type: UnificationXref
id: REACT_87166
db: Reactome
id version: 4
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_87166.4

UnificationXref4802
type: UnificationXref
id: 5594392
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594392

UniProt:PF10_0041
type: ProteinReference
xref: UnificationXref5431
organism: http://identifiers.org/taxonomy/5833

UnificationXref4801
type: UnificationXref
id: 5594390
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594390

UnificationXref4800
type: UnificationXref
id: 5594384
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594384

UnificationXref4808
type: UnificationXref
id: 379720
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379720

Formation of a pool of free 40S subunits
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction397
evidence: Evidence819
xref: UnificationXref4677
xref: UnificationXref4678
pathway order: PathwayStep798
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

UnificationXref4809
type: UnificationXref
id: REACT_15727
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15727.1

pyruvoyl group
type: SmallMoleculeReference
name: pyruvoyl group [ChEBI:45360]
name: CH3-CO-CO-
xref: UnificationXref1669

UnificationXref3240
type: UnificationXref
id: MAL13P1.119
db: UniProt

http://identifiers.org/pubmed/5324173
type: PublicationXref
id: 5324173
author: Berg, P
author: Baldwin, AN
db: Pubmed
title: Transfer ribonucleic acid-induced hydrolysis of valyladenylate bound to isoleucyl ribonucleic acid synthetase
source: J Biol Chem 241:839-45
year: 1966

http://identifiers.org/pubmed/5324172
type: PublicationXref
id: 5324172
author: Berg, P
author: Baldwin, AN
db: Pubmed
title: Purification and properties of isoleucyl ribonucleic acid synthetase from Escherichia coli
source: J Biol Chem 241:831-8
year: 1966

UniProt:PF10_0038
type: ProteinReference
xref: UnificationXref3484
organism: http://identifiers.org/taxonomy/5833

UnificationXref3245
type: UnificationXref
id: 5595267
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595267

UnificationXref3246
type: UnificationXref
id: PF14_0672
db: UniProt

PF10_0203
type: Protein
entity reference: PF10_0203
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Arf1
xref: UnificationXref5889
feature: FragmentFeature794
cellular location: GO_0005829
comment: Reactome DB_ID: 5594801
display name: ARF1

UnificationXref3247
type: UnificationXref
id: 5595269
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595269

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFI0290c
data source: Provenance1
name: PFI0290c
name: Coatomer beta' subunit
xref: UnificationXref5869
feature: FragmentFeature793
cellular location: GO_0005829
comment: Reactome DB_ID: 5594779
display name: COPB2

UnificationXref3248
type: UnificationXref
id: 5595270
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595270

Coproporphyrinogen I
type: SmallMoleculeReference
name: Coproporphyrinogen I [ChEBI:3879]
xref: UnificationXref2995

UnificationXref3241
type: UnificationXref
id: 5595263
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595263

UnificationXref3242
type: UnificationXref
id: PFL0475w
db: UniProt

http://identifiers.org/pubmed/18802415
type: PublicationXref
id: 18802415
author: Ko, CH
author: Takahashi, JS
author: Hong, HK
author: McDearmon, EL
db: Pubmed
title: The genetics of mammalian circadian order and disorder: implications for physiology and disease
source: Nat Rev Genet 9:764-75
year: 2008

UnificationXref4810
type: UnificationXref
id: CHEBI:29265
db: ChEBI

UnificationXref3243
type: UnificationXref
id: 5595265
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595265

UnificationXref3244
type: UnificationXref
id: MAL13P1.118
db: UniProt

UnificationXref4812
type: UnificationXref
id: REACT_15840
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15840.1

UnificationXref4811
type: UnificationXref
id: 379728
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379728

UniProt:PFA0355w
type: ProteinReference
xref: UnificationXref3934
organism: http://identifiers.org/taxonomy/5833

UnificationXref4814
type: UnificationXref
id: 379707
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379707

UnificationXref4813
type: UnificationXref
id: CHEBI:29158
db: ChEBI

UnificationXref4816
type: UnificationXref
id: CHEBI:29152
db: ChEBI

UnificationXref3249
type: UnificationXref
id: 5595272
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595272

UnificationXref4815
type: UnificationXref
id: REACT_15677
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15677.1

UnificationXref4818
type: UnificationXref
id: REACT_15780
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15780.1

UnificationXref4817
type: UnificationXref
id: 379719
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379719

UnificationXref4819
type: UnificationXref
id: CHEBI:29166
db: ChEBI

UnificationXref3251
type: UnificationXref
id: 5596971
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596971

http://identifiers.org/pubmed/1592113
type: PublicationXref
id: 1592113
author: Powell, SM
author: Dixon, JE
author: Zalkin, H
db: Pubmed
title: Cloning and characterization of the cDNA encoding human adenylosuccinate synthetase
source: FEBS Lett 303:4-20
year: 1992

UnificationXref3250
type: UnificationXref
id: REACT_177159
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_177159.3

http://identifiers.org/pubmed/15526160
type: PublicationXref
id: 15526160
author: Rönnstrand, L
db: Pubmed
title: Signal transduction via the stem cell factor receptor/c-Kit
source: Cell Mol Life Sci 61:2535-48
year: 2004

Glycogen breakdown (glycogenolysis)
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction66
evidence: Evidence141
xref: UnificationXref833
xref: RelationshipXref105
xref: UnificationXref832
pathway order: PathwayStep139
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/11698410
type: PublicationXref
id: 11698410
author: Bambara, RA
author: DeMott, Michael S
author: Ranalli, TA
db: Pubmed
title: Mechanism underlying replication protein a stimulation of DNA ligase I
source: J. Biol. Chem. 277:1719-27
year: 2002

UnificationXref3258
type: UnificationXref
id: REACT_236984
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_236984.1

UnificationXref3259
type: UnificationXref
id: 5596968
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596968

UnificationXref3256
type: UnificationXref
id: REACT_262401
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_262401.1

UnificationXref3257
type: UnificationXref
id: 5596967
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596967

UnificationXref4821
type: UnificationXref
id: REACT_15566
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_15566.1

UnificationXref3254
type: UnificationXref
id: REACT_246778
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_246778.1

UnificationXref4820
type: UnificationXref
id: 379772
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379772

UnificationXref3255
type: UnificationXref
id: 5596966
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596966

UnificationXref3252
type: UnificationXref
id: REACT_243010
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_243010.1

UnificationXref3253
type: UnificationXref
id: 5596972
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596972

UnificationXref4825
type: UnificationXref
id: CHEBI:29156
db: ChEBI

UnificationXref4824
type: UnificationXref
id: REACT_16052
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_16052.1

UnificationXref4823
type: UnificationXref
id: 379751
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379751

UnificationXref4822
type: UnificationXref
id: CHEBI:29157
db: ChEBI

UnificationXref4829
type: UnificationXref
id: 379786
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379786

UnificationXref4828
type: UnificationXref
id: CHEBI:29155
db: ChEBI

UnificationXref4827
type: UnificationXref
id: REACT_18164
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_18164.1

UnificationXref4826
type: UnificationXref
id: 379784
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=379784

AKT phosphorylates targets in the cytosol
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction38
evidence: Evidence76
xref: UnificationXref506
xref: UnificationXref507
pathway order: PathwayStep74
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

Aspartyl-tRNA synthetase
type: Protein
entity reference: PFA0145c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: PFA0145c
xref: UnificationXref5472
feature: FragmentFeature745
cellular location: GO_0005829
comment: Reactome DB_ID: 5595046
display name: DARS

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL0670c
data source: Provenance1
name: Bifunctional aminoacyl-tRNA synthetase
name: PFL0670c
xref: UnificationXref5470
feature: FragmentFeature744
cellular location: GO_0005829
comment: Reactome DB_ID: 5595049
display name: EPRS

UnificationXref450
type: UnificationXref
id: REACT_12312
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_12312.3

UnificationXref451
type: UnificationXref
id: PF10_0132
db: UniProt

UnificationXref452
type: UnificationXref
id: MOD:00048
db: MOD

UnificationXref3260
type: UnificationXref
id: REACT_247292
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_247292.1

UnificationXref453
type: UnificationXref
id: 5594469
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594469

UnificationXref3261
type: UnificationXref
id: MAL13P1.309
db: UniProt

UnificationXref454
type: UnificationXref
id: 5594471
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594471

UnificationXref3262
type: UnificationXref
id: 5595406
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595406

http://identifiers.org/pubmed/18400693
type: PublicationXref
id: 18400693
author: Dorwart, MR
author: Muallem, S
author: Yang, D
author: Shcheynikov, N
db: Pubmed
title: The solute carrier 26 family of proteins in epithelial ion transport
source: Physiology (Bethesda) 23:104-14
year: 2008

http://identifiers.org/pubmed/11502751
type: PublicationXref
id: 11502751
author: Nagata, E
author: Luo, HR
author: Saiardi, A
author: Snowman, AM
author: Snyder, SH
db: Pubmed
title: Identification and characterization of a novel inositol hexakisphosphate kinase
source: J Biol Chem 276:39179-85
year: 2001

http://identifiers.org/pubmed/10660545
type: PublicationXref
id: 10660545
author: Fishel, R
author: Acharya, S
author: Gradia, S
db: Pubmed
title: The role of mismatched nucleotides in activating the hMSH2-hMSH6 molecular switch
source: J. Biol. Chem. 275:3922-30
year: 2000

PF10_0340
type: Protein
entity reference: PF10_0340
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Methionyl-tRNA synthetase
xref: UnificationXref5468
feature: FragmentFeature743
cellular location: GO_0005829
comment: Reactome DB_ID: 5595058
display name: MARS

U5 snRNP-associated 102 kDa protein
type: Protein
entity reference: PF11_0108
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: PRPU_HUMAN
name: U5-102 kDa protein
name: PF11_0108
xref: UnificationXref5434
feature: FragmentFeature741
cellular location: GO_0005654
comment: Reactome DB_ID: 5594060
display name: PRPF6

UnificationXref445
type: UnificationXref
id: CHEBI:16595
db: ChEBI

UnificationXref3264
type: UnificationXref
id: 5595447
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595447

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF13_0354
data source: Provenance1
name: PF13_0354
name: Alanyl-tRNA synthetase
xref: UnificationXref5461
feature: FragmentFeature742
cellular location: GO_0005829
comment: Reactome DB_ID: 5595069
display name: AARS

UnificationXref444
type: UnificationXref
id: REACT_12371
db: Reactome
id version: 4
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_12371.4

UnificationXref3263
type: UnificationXref
id: 5595407
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595407

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFD1060w
data source: Provenance1
name: U5-200kDa helicase
name: U520_HUMAN
name: U5 small nuclear ribonucleoprotein 200 kDa helicase
name: U5-200KD
name: PFD1060w
name: U5 snRNP-specific 200 kDa protein
xref: UnificationXref5430
feature: FragmentFeature739
cellular location: GO_0005654
comment: Reactome DB_ID: 5594064
display name: SNRNP200

UnificationXref447
type: UnificationXref
id: REACT_2897
db: Reactome
id version: 4
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_2897.4

UnificationXref3266
type: UnificationXref
id: 5595449
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595449

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PF10_0041
data source: Provenance1
name: 116 kDa U5 small nuclear ribonucleoprotein component (U5 snRNP- specific protein, 116 kDa) (U5-116 kDa)
name: U5 snRNP- specific protein, 116 kDa
name: U5S1_HUMAN
name: U5-116 kDa protein
name: PF10_0041
name: U5-116 kDa
name: 116 kDa U5 small nuclear ribonucleoprotein component
xref: UnificationXref5432
feature: FragmentFeature740
cellular location: GO_0005654
comment: Reactome DB_ID: 5594062
display name: EFTUD2

UnificationXref446
type: UnificationXref
id: 114520
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=114520

UnificationXref3265
type: UnificationXref
id: 5595448
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595448

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF11_0250
data source: Provenance1
name: PF11_0250
name: High mobility group-like nuclear protein 2 homolog 1
name: (U4/U6.U5) tri-snRNP 15.5 kDa protein
name: NHP2L1
name: tri-snRNP 15.5 kDa protein
name: NHP2-like protein 1
xref: UnificationXref5426
feature: FragmentFeature737
cellular location: GO_0005654
comment: Reactome DB_ID: 5594066
display name: OTK27

UnificationXref449
type: UnificationXref
id: 112275
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=112275

UnificationXref3268
type: UnificationXref
id: 5596997
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596997

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL1520w
data source: Provenance1
name: DIM1_HUMAN
name: Spliceosomal U5 snRNP-specific 15 kDa protein
name: PFL1520w
name: Thioredoxin-like U5 snRNP protein U5-15kD
name: DIM1 protein homolog
name: TXNL4A
xref: UnificationXref5428
feature: FragmentFeature738
cellular location: GO_0005654
comment: Reactome DB_ID: 5594054
display name: DIM1

UnificationXref448
type: UnificationXref
id: CHEBI:18035
db: ChEBI

UnificationXref3267
type: UnificationXref
id: REACT_254919
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_254919.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFE0925c
data source: Provenance1
name: PFE0925c
name: U5-100 kDa protein
xref: UnificationXref5422
feature: FragmentFeature735
cellular location: GO_0005654
comment: Reactome DB_ID: 5594058
display name: DDX23

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFD0265w
data source: Provenance1
name: hPrp8
name: PFD0265w
xref: UnificationXref5424
feature: FragmentFeature736
cellular location: GO_0005654
comment: Reactome DB_ID: 5594070
display name: PRPF8

UnificationXref3269
type: UnificationXref
id: REACT_239738
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_239738.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0198
data source: Provenance1
name: PF14_0198
name: Glycyl-tRNA synthetase
name: GARS(55-739)
xref: UnificationXref5524
feature: FragmentFeature754
cellular location: GO_0005829
comment: Reactome DB_ID: 5595122
display name: GARS

UnificationXref460
type: UnificationXref
id: REACT_250838
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_250838.1

UnificationXref461
type: UnificationXref
id: 5596731
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596731

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF07_0073
data source: Provenance1
name: Seryl-tRNA synthetase
name: PF07_0073
xref: UnificationXref5564
feature: FragmentFeature756
cellular location: GO_0005829
comment: Reactome DB_ID: 5595098
display name: SARS

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0428
data source: Provenance1
name: Histidyl-tRNA synthetase
name: PF14_0428
xref: UnificationXref5532
feature: FragmentFeature755
cellular location: GO_0005829
comment: Reactome DB_ID: 5595042
display name: HARS

UnificationXref464
type: UnificationXref
id: REACT_259160
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_259160.1

UnificationXref3272
type: UnificationXref
id: PF14_0681
db: UniProt

http://identifiers.org/pubmed/7544491
type: PublicationXref
id: 7544491
author: Yu, J
author: Allsopp, RC
author: Chiu, CP
author: Funk, WD
author: Avilion, AA
author: Feng, J
author: Chang, E
author: Adams, RR
author: Weinrich, SL
author: Wang, SS
db: Pubmed
title: The RNA component of human telomerase
source: Science 269:1236-41
year: 1995

UnificationXref465
type: UnificationXref
id: 5596748
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596748

UnificationXref3273
type: UnificationXref
id: 5595290
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595290

UnificationXref462
type: UnificationXref
id: REACT_260544
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_260544.1

UnificationXref3270
type: UnificationXref
id: 5596849
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596849

http://identifiers.org/pubmed/2462567
type: PublicationXref
id: 2462567
author: de Jong, WW
author: Stapel, SO
author: Lietman, T
author: Wistow, GJ
author: Piatigorsky, J
author: Williams, LA
author: Horwitz, J
db: Pubmed
title: Tau-crystallin/alpha-enolase: one gene encodes both an enzyme and a lens structural protein
source: J Cell Biol 107:2729-36
year: 1988

UnificationXref463
type: UnificationXref
id: 5596738
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596738

UnificationXref3271
type: UnificationXref
id: REACT_240387
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_240387.1

UniProt:PF10_0084
type: ProteinReference
xref: UnificationXref4944
organism: http://identifiers.org/taxonomy/5833

UniProt:PF10_0081
type: ProteinReference
xref: UnificationXref3733
organism: http://identifiers.org/taxonomy/5833

UniProt:PF10_0086
type: ProteinReference
xref: UnificationXref2492
organism: http://identifiers.org/taxonomy/5833

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF13_0179
data source: Provenance1
name: Isoleucyl-tRNA synthetase
name: PF13_0179
xref: UnificationXref5484
feature: FragmentFeature750
cellular location: GO_0005829
comment: Reactome DB_ID: 5595051
display name: IARS

UnificationXref458
type: UnificationXref
id: 5593938
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593938

UnificationXref3277
type: UnificationXref
id: 5595295
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595295

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0401
data source: Provenance1
name: PF14_0401
name: AIMP1(1-312)
name: Multisynthetase complex auxiliary component p43
xref: UnificationXref5486
feature: FragmentFeature751
cellular location: GO_0005829
comment: Reactome DB_ID: 5595062
display name: SCYE1

UnificationXref457
type: UnificationXref
id: 5593937
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593937

UnificationXref3276
type: UnificationXref
id: 5595293
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595293

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFB0525w
data source: Provenance1
name: Asparaginyl-tRNA synthetase
name: PFB0525w
xref: UnificationXref5494
feature: FragmentFeature752
cellular location: GO_0005829
comment: Reactome DB_ID: 5595107
display name: NARS

UnificationXref456
type: UnificationXref
id: PF14_0323
db: UniProt

UnificationXref3275
type: UnificationXref
id: 5595292
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595292

PF10_0149
type: Protein
entity reference: PF10_0149
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Cysteinyl-tRNA synthetase
xref: UnificationXref5506
feature: FragmentFeature753
cellular location: GO_0005829
comment: Reactome DB_ID: 5595077
display name: CARS

UnificationXref455
type: UnificationXref
id: REACT_236499
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_236499.1

UnificationXref3274
type: UnificationXref
id: PFI1485c
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFL0900c
data source: Provenance1
name: Arginyl-tRNA synthetase
name: PFL0900c
xref: UnificationXref5475
feature: FragmentFeature746
cellular location: GO_0005829
comment: Reactome DB_ID: 5595064
display name: RARS

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF13_0262
data source: Provenance1
name: Lysyl-tRNA synthetase
name: PF13_0262
xref: UnificationXref5477
feature: FragmentFeature747
cellular location: GO_0005829
comment: Reactome DB_ID: 5595053
display name: KARS

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFF1095w
data source: Provenance1
name: PFF1095w
name: Leucyl-tRNA synthetase
xref: UnificationXref5480
feature: FragmentFeature748
cellular location: GO_0005829
comment: Reactome DB_ID: 5595056
display name: LARS

UnificationXref3279
type: UnificationXref
id: 5596973
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596973

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF13_0257
data source: Provenance1
name: Glutaminyl-tRNA synthetase
name: PF13_0257
xref: UnificationXref5482
feature: FragmentFeature749
cellular location: GO_0005829
comment: Reactome DB_ID: 5595060
display name: QARS

UnificationXref459
type: UnificationXref
id: 5593939
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5593939

UnificationXref3278
type: UnificationXref
id: REACT_248644
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_248644.1

UnificationXref473
type: UnificationXref
id: 5594172
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594172

UnificationXref3281
type: UnificationXref
id: GO:0031093
db: GENE ONTOLOGY

UnificationXref474
type: UnificationXref
id: REACT_261202
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_261202.1

UnificationXref3282
type: UnificationXref
id: 5595559
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595559

http://identifiers.org/pubmed/12324224
type: PublicationXref
id: 12324224
author: Sprecher, H
db: Pubmed
title: The roles of anabolic and catabolic reactions in the synthesis and recycling of polyunsaturated fatty acids
source: Prostaglandins Leukot Essent Fatty Acids 67:79-83
year: 2002

UnificationXref475
type: UnificationXref
id: 5596791
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596791

UnificationXref3283
type: UnificationXref
id: 5595560
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595560

UnificationXref476
type: UnificationXref
id: REACT_253567
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_253567.1

UnificationXref3284
type: UnificationXref
id: 5595561
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595561

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: MAL13P1.281
data source: Provenance1
name: MAL13P1.281
name: Glutamyl-tRNA synthetase 2
xref: UnificationXref5643
feature: FragmentFeature766
cellular location: GO_0005759
comment: Reactome DB_ID: 5595157
display name: EARS2

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0166
data source: Provenance1
name: PF14_0166
name: Aspartyl-tRNA synthetase 2
xref: UnificationXref5634
feature: FragmentFeature765
cellular location: GO_0005759
comment: Reactome DB_ID: 5595169
display name: DARS2

UnificationXref470
type: UnificationXref
id: MAL8P1.69
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFE0475w
data source: Provenance1
name: PFE0475w
name: Asparaginyl-tRNA synthetase 2
xref: UnificationXref5626
feature: FragmentFeature764
cellular location: GO_0005759
comment: Reactome DB_ID: 5595165
display name: NARS2

UnificationXref471
type: UnificationXref
id: 5594170
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594170

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF13_0354
data source: Provenance1
name: PF13_0354
name: Alanyl-tRNA synthetase 2
xref: UnificationXref5616
feature: FragmentFeature763
cellular location: GO_0005759
comment: Reactome DB_ID: 5595135
display name: AARS2

UnificationXref472
type: UnificationXref
id: 5594171
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594171

UnificationXref3280
type: UnificationXref
id: REACT_244972
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_244972.1

http://identifiers.org/pubmed/17127307
type: PublicationXref
id: 17127307
author: Luckashenak, N
author: Clements, JL
db: Pubmed
title: Signaling mechanisms utilized by antigen receptors and integrins: common intermediates, different outcomes?
source: Front Biosci 12:419-36
year: 2007

UniProt:PF10_0077
type: ProteinReference
xref: UnificationXref3529
organism: http://identifiers.org/taxonomy/5833

http://identifiers.org/pubmed/11533233
type: PublicationXref
id: 11533233
author: Fox, PL
author: Sonenberg, N
author: Imataka, H
author: Seshadri, V
author: Mazumder, B
db: Pubmed
title: Translational silencing of ceruloplasmin requires the essential elements of mRNA circularization: poly(A) tail, poly(A)-binding protein, and eukaryotic translation initiation factor 4G
source: Mol Cell Biol 21:6440-9
year: 2001

Synthesis of PG
type: Pathway
data source: Provenance1
pathway component: BiochemicalReaction161
pathway component: BiochemicalReaction160
evidence: Evidence305
xref: RelationshipXref283
xref: UnificationXref1786
xref: UnificationXref1787
pathway order: PathwayStep301
pathway order: PathwayStep302
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:MAL8P1.125
data source: Provenance1
name: MAL8P1.125
name: Tyrosyl-tRNA synthetase
xref: UnificationXref5588
feature: FragmentFeature759
cellular location: GO_0005829
comment: Reactome DB_ID: 5595091
display name: YARS

http://identifiers.org/pubmed/9741684
type: PublicationXref
id: 9741684
author: Edwards, PA
author: Shell, BK
author: Greene, JM
author: Ericsson, J
author: Carter, KC
author: Florence, C
author: Duan, DR
db: Pubmed
title: Human geranylgeranyl diphosphate synthase: isolation of the cDNA, chromosomal mapping and tissue expression
source: J Lipid Res 39:1731-9
year: 1998

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0589
data source: Provenance1
name: PF14_0589
name: Valyl-tRNA synthetase
xref: UnificationXref5596
feature: FragmentFeature760
cellular location: GO_0005829
comment: Reactome DB_ID: 5595118
display name: VARS

UnificationXref3289
type: UnificationXref
id: PFA0260c
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF11_0270
data source: Provenance1
name: PF11_0270
name: Threonyl-tRNA synthetase
xref: UnificationXref5572
feature: FragmentFeature757
cellular location: GO_0005829
comment: Reactome DB_ID: 5595111
display name: TARS

PF13_0205
type: Protein
entity reference: PF13_0205
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Tryptophanyl-tRNA synthetase
xref: UnificationXref5580
feature: FragmentFeature758
cellular location: GO_0005829
comment: Reactome DB_ID: 5595086
display name: WARS

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFC0710w.1
data source: Provenance1
name: Pyrophosphate phospho-hydrolase
name: PFC0710w.1
name: Inorganic pyrophosphatase
name: pyrophosphatase (inorganic) 1
xref: UnificationXref5602
feature: FragmentFeature762
cellular location: GO_0005829
comment: Reactome DB_ID: 5593583
display name: PPA1

UnificationXref467
type: UnificationXref
id: PFB0520w
db: UniProt

UnificationXref3286
type: UnificationXref
id: 5595570
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595570

UnificationXref466
type: UnificationXref
id: REACT_261823
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_261823.1

UnificationXref3285
type: UnificationXref
id: REACT_243015
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_243015.1

Homologues of PPA1
type: Protein
data source: Provenance1
member physical entity: Note: the coordinates are copied over from Homo sapiens.
xref: UnificationXref5603
cellular location: GO_0005829
comment: Reactome DB_ID: 5593584
comment: Converted from EntitySet in Reactome

UnificationXref469
type: UnificationXref
id: 5594168
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594168

UnificationXref3288
type: UnificationXref
id: REACT_252310
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_252310.1

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: UniProt:PFC0710w.2
data source: Provenance1
name: Pyrophosphate phospho-hydrolase
name: PFC0710w.2
name: Inorganic pyrophosphatase
name: pyrophosphatase (inorganic) 1
xref: UnificationXref5600
feature: FragmentFeature761
cellular location: GO_0005829
comment: Reactome DB_ID: 5593581
display name: PPA1

UnificationXref468
type: UnificationXref
id: MOD:00046
db: MOD

UnificationXref3287
type: UnificationXref
id: 5595571
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595571

UnificationXref486
type: UnificationXref
id: PFL2250c
db: UniProt

UnificationXref3294
type: UnificationXref
id: 5595575
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595575

http://identifiers.org/pubmed/19021507
type: PublicationXref
id: 19021507
author: Johnson, MK
author: Chandramouli, K
author: Bandyopadhyay, S
db: Pubmed
title: Iron-sulfur cluster biosynthesis
source: Biochem Soc Trans 36:1112-9
year: 2008

UnificationXref487
type: UnificationXref
id: 5594733
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5594733

UnificationXref3295
type: UnificationXref
id: 5595576
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595576

PFF0180w
type: Protein
entity reference: PFF0180w
data source: Provenance1
xref: UnificationXref5707
cellular location: GO_0005759
comment: Reactome DB_ID: 5595153

UnificationXref484
type: UnificationXref
id: 179838
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=179838

UnificationXref3292
type: UnificationXref
id: 5595247
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595247

UnificationXref485
type: UnificationXref
id: REACT_12989
db: Reactome
id version: 3
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_12989.3

UnificationXref3293
type: UnificationXref
id: 5595574
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595574

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL0770w
data source: Provenance1
name: Seryl-tRNA synthetase 2
name: PFL0770w
xref: UnificationXref5725
feature: FragmentFeature773
cellular location: GO_0005759
comment: Reactome DB_ID: 5595181
display name: SARS2

UnificationXref482
type: UnificationXref
id: REACT_241299
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_241299.1

UnificationXref3290
type: UnificationXref
id: 5595573
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5595573

PFI1240c
type: Protein
entity reference: PFI1240c
data source: Provenance1
name: Note: the coordinates are copied over from Homo sapiens.
name: Prolyl-tRNA synthetase 2
xref: UnificationXref5715
feature: FragmentFeature772
cellular location: GO_0005759
comment: Reactome DB_ID: 5595139
display name: PARS2

UnificationXref483
type: UnificationXref
id: CHEBI:16618
db: ChEBI

UnificationXref3291
type: UnificationXref
id: PF13_0326
db: UniProt

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PFL2485c
data source: Provenance1
name: Tryptophanyl-tRNA synthetase 2
name: PFL2485c
xref: UnificationXref5744
feature: FragmentFeature774
cellular location: GO_0005759
comment: Reactome DB_ID: 5595161
display name: WARS2

UnificationXref480
type: UnificationXref
id: REACT_242135
db: Reactome
id version: 1
comment: Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_242135.1

PF11_0270
type: Protein
entity reference: PF11_0270
data source: Provenance1
xref: UnificationXref5735
cellular location: GO_0005759
comment: Reactome DB_ID: 5595149

UnificationXref481
type: UnificationXref
id: 5596809
db: Reactome Database ID Release 49
comment: Database identifier. Use this URL to connect to the web page of this instance in Reactome: http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&ID=5596809

Processing of Capped Intron-Containing Pre-mRNA
type: Pathway
data source: Provenance1
pathway component: REACT 259411.1
evidence: Evidence950
xref: UnificationXref5457
xref: UnificationXref5456
pathway order: PathwayStep928
comment: This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.
organism: http://identifiers.org/taxonomy/5833

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF13_0257
data source: Provenance1
name: Glutaminyl-tRNA synthetase
name: PF13_0257
xref: UnificationXref5652
feature: FragmentFeature767
cellular location: GO_0005759
comment: Reactome DB_ID: 5595189
display name: QARS

Note: the coordinates are copied over from Homo sapiens.
type: Protein
entity reference: PF14_0198
data source: Provenance1
name: PF14_0198
name: Glycyl-tRNA synthetase
xref: UnificationXref5659
feature: FragmentFeature768
cellular location: GO_0005759
comment: Reactome DB_ID: 5595185
display name: GARS