Bacterial dihydrofolate reductase inhibitor
Sodium-(potassium)-chloride cotransporter 2 inhibitor
Norepinephrine transporter releasing agent
GABA-A receptor; anion channel allosteric antagonist
Muscarinic acetylcholine receptor M3 agonist
Succinate semialdehyde dehydrogenase inhibitor
Bacterial dihydropteroate synthase inhibitor
GABA-A receptor; anion channel positive allosteric modulator
Human immunodeficiency virus type 1 reverse transcriptase inhibitor
Serotonin 2c (5-HT2c) receptor antagonist
Serotonin 2a (5-HT2a) receptor antagonist
Estrogen-related receptor gamma antagonist
Bacterial enoyl-[acyl-carrier-protein] reductase inhibitor
Muscarinic acetylcholine receptor M1 agonist
GABA-A receptor negative allosteric modulator
Vascular endothelial growth factor receptor inhibitor
Tyrosine-protein kinase receptor RET inhibitor
Epidermal growth factor receptor inhibitor
Glutamate NMDA receptor; GRIN1/GRIN2B antagonist
GABA-A receptor; anion channel positive modulator
3',5'-cyclic phosphodiesterase inhibitor
DNA polymerase/reverse transcriptase inhibitor
Gonadotropin-releasing hormone receptor antagonist
Vitamin k epoxide reductase complex subunit 1 isoform 1 inhibitor
Glucagon-like peptide 1 receptor agonist
DNA polymerase (alpha/delta/epsilon) inhibitor
Voltage-gated L-type calcium channel blocker
Voltage-gated N-type calcium channel alpha-1B subunit blocker
Voltage-gated P/Q-type calcium channel alpha-1A subunit blocker
Sodium channel protein type III alpha subunit blocker
Sodium channel protein type II alpha subunit blocker
CRL4(CRBN) E3 ubiquitin ligase inhibitor
Peroxisome proliferator-activated receptor gamma agonist
Bacterial penicillin-binding protein inhibitor
Thiazide-sensitive sodium-chloride cotransporter inhibitor
Tyrosine-protein kinase receptor FLT3 inhibitor
Fibroblast growth factor receptor inhibitor
Serine/threonine-protein kinase Aurora-A inhibitor
Vascular endothelial growth factor receptor 2 inhibitor
Platelet-derived growth factor receptor inhibitor
Human herpesvirus 1 DNA polymerase inhibitor
Solute carrier family 22 member 12 inhibitor
Voltage-activated calcium channel beta 2 subunit blocker
Voltage-activated calcium channel beta 1 subunit blocker
Muscle-type nicotinic acetylcholine receptor agonist
Type-1 angiotensin II receptor antagonist
Stem cell growth factor receptor inhibitor
Tissue-type plasminogen activator inhibitor
Endothelin receptor, ET-A/ET-B antagonist
Macrophage colony stimulating factor receptor inhibitor
Peroxisome proliferator-activated receptor gamma modulator
Voltage-gated T-type calcium channel blocker
Muscle-type nicotinic acetylcholine receptor partial agonist
Platelet-derived growth factor receptor beta inhibitor
Neuronal acetylcholine receptor; alpha4/beta2 agonist
Synaptic vesicular amine transporter inhibitor
Inhibitor of nuclear factor kappa B kinase beta subunit inhibitor
Muscarinic acetylcholine receptor M3 antagonist
Muscarinic acetylcholine receptor M2 antagonist
4-hydroxyphenylpyruvate dioxygenase inhibitor
Peroxisome proliferator-activated receptor alpha agonist
Nicotinamide phosphoribosyltransferase inhibitor
Neuronal acetylcholine receptor; alpha4/beta2 partial agonist
Human immunodeficiency virus type 1 integrase inhibitor
Sodium channel protein type IV alpha subunit blocker
Sodium channel protein type V alpha subunit blocker
Calcitonin gene-related peptide type 1 receptor antagonist
Calcium-activated potassium channel subunit alpha-1 activator
Hepatitis C virus serine protease, NS3/NS4A inhibitor
Alpha-1a adrenergic receptor partial agonist
Sodium/potassium-transporting ATPase inhibitor
DNA (cytosine-5)-methyltransferase 3A inhibitor
DNA (cytosine-5)-methyltransferase 1 inhibitor
Hepatocyte growth factor receptor inhibitor
Macrophage-stimulating protein receptor inhibitor
Voltage-sensitive sodium channel blocker
Voltage-gated potassium channel subunit Kv7.5 activator
Voltage-gated potassium channel subunit Kv7.4 activator
Voltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3) activator
Calcium-activated potassium channel subunit alpha-1 opener
Voltage-gated potassium channel subunit Kv7.2 activator
Voltage-gated potassium channel KCNQ3/KCNQ4 activator
Enoyl-[acyl-carrier-protein] reductase inhibitor
GABA receptor alpha-1 subunit positive allosteric modulator
Muscle-type nicotinic acetylcholine receptor antagonist
Amiloride-sensitive sodium channel, ENaC blocker
Bacterial penicillin-binding protein 2 inhibitor
Beta-2 adrenergic receptor partial agonist
Beta-1 adrenergic receptor partial agonist
Nematode GABA-A receptor positive modulator
Human immunodeficiency virus type 1 protease inhibitor
Mitogen-activated protein kinase kinase kinase 12 inhibitor
Mitogen-activated protein kinase kinase kinase 11 inhibitor
Mitogen-activated protein kinase kinase kinase 10 inhibitor
Mitogen-activated protein kinase kinase kinase 9 inhibitor
Mitogen-activated protein kinase kinase kinase 13 inhibitor
Solute carrier family 22 member 8 inhibitor
Solute carrier family 22 member 11 inhibitor
Solute carrier family 22 member 6 inhibitor
Cholesteryl ester transfer protein inhibitor
Plasminogen activator inhibitor-1 inhibitor
Serotonin 1a (5-HT1a) receptor partial agonist
Glycogen synthase kinase-3 beta inhibitor
Glycogen synthase kinase-3 alpha inhibitor
Metabotropic glutamate receptor 2 agonist
Metabotropic glutamate receptor 3 agonist
Pyruvate:ferredoxin oxidoreductase inhibitor
Purinergic receptor P2Y12 negative allosteric modulator
Potassium channel, inwardly rectifying, subfamily J, member 8 opener
Potassium channel, inwardly rectifying, subfamily J, member 11 opener
Glutamate [NMDA] receptor negative allosteric modulator
Intermediate conductance calcium-activated potassium channel protein 4 blocker
Serine/threonine-protein kinase Aurora inhibitor
Vascular endothelial growth factor receptor 1 inhibitor
Fibroblast growth factor receptor 2 inhibitor
Fibroblast growth factor receptor 1 inhibitor
Serine/threonine-protein kinase Aurora-B inhibitor
Muscarinic acetylcholine receptor M1 antagonist
Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor
Epidermal growth factor receptor erbB1 inhibitor
Equilibrative nucleoside transporter 1 inhibitor
Neuronal acetylcholine receptor protein alpha-7 subunit positive allosteric modulator
Bacterial DNA-directed RNA polymerase inhibitor
DNA topoisomerase I, mitochondrial inhibitor
Fibroblast growth factor receptor 3 inhibitor
Corticotropin releasing factor receptor 1 antagonist
Dual specificity mitogen-activated protein kinase kinase 2 inhibitor
Dual specificity mitogen-activated protein kinase kinase 1 inhibitor
Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor
Inosine-5'-monophosphate dehydrogenase 1 inhibitor
Sphingosine 1-phosphate receptor agonist
Transmembrane glycoprotein gp41 inhibitor
Amidophosphoribosyltransferase inhibitor
Mitochondrial glycerol-3-phosphate dehydrogenase inhibitor
Mitochondrial complex I (NADH dehydrogenase) inhibitor
Insulin-like growth factor I receptor inhibitor
Ribonucleoside-diphosphate reductase RR1 inhibitor
Nerve growth factor receptor Trk-A inhibitor
Muscarinic acetylcholine receptor M2 agonist
Serine/threonine-protein kinase mTOR inhibitor
Neurotrophic tyrosine kinase receptor type 2 inhibitor
Poly [ADP-ribose] polymerase-1 inhibitor
Poly [ADP-ribose] polymerase 2 inhibitor
Sphingosine 1-phosphate receptor Edg-1 agonist
Mitogen-activated protein kinase kinase kinase 1 inhibitor
Serine/threonine-protein kinase Aurora-C inhibitor
Serine/threonine-protein kinase PLK1 inhibitor
Fibroblast growth factor receptor 2 agonist
Vascular endothelial growth factor A inhibitor
Cysteinyl leukotriene receptor 1 antagonist
Gonadotropin-releasing hormone receptor agonist
Tyrosine-protein kinase ITK/TSK inhibitor
Serine/threonine-protein kinase B-raf inhibitor
Serine/threonine-protein kinase RAF inhibitor
Inositol-1(or 4)-monophosphatase 1 inhibitor
D2-like dopamine receptor inverse agonist
Serotonin 2b (5-HT2b) receptor partial agonist
Betaine-homocysteine S-methyltransferase substrate
Opioid receptors; mu/kappa/delta agonist
Glycine receptor (alpha-1/beta) positive modulator
Potassium channel subfamily K member 3 opener
Potassium channel subfamily K member 2 opener
Potassium channel subfamily K member 18 opener
Potassium channel subfamily K member 10 opener
Potassium channel subfamily K member 9 opener
Opioid receptors; mu/kappa/delta antagonist
C-C chemokine receptor type 5 antagonist
Luteinizing hormone/Choriogonadotropin receptor agonist
Glutamate [NMDA] receptor subunit epsilon 1 antagonist
Growth hormone-releasing hormone receptor agonist
Myeloid cell surface antigen CD33 binding agent
Major intermediate early region 2 mRNA antisense inhibitor
Thyroid stimulating hormone receptor agonist
Granulocyte colony stimulating factor receptor agonist
Vesicle-associated membrane protein 2 inhibitor
Integrin alpha-L/beta-2 (LFA-1) inhibitor
Receptor protein-tyrosine kinase erbB-2 inhibitor
Calcium sensing receptor positive allosteric modulator
Follicle stimulating hormone receptor agonist
Insulin-like growth factor I receptor agonist
C-X-C chemokine receptor type 4 partial agonist
Mycobacterium tuberculosis H37Rv inhibitor
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 blocker
Inward rectifier potassium channel 2 blocker
Glutamate-gated chloride channel modulator
Potassium channel subfamily K member 3 blocker
Potassium channel subfamily K member 9 blocker
Nicotinic acetylcholine receptor alpha4/beta2/alpha5 partial agonist
Neuronal acetylcholine receptor; alpha6/beta2 partial agonist
Interleukin-6 receptor alpha subunit inhibitor
Tumor necrosis factor ligand superfamily member 11 inhibitor
Niemann-Pick C1-like protein 1 inhibitor
cAMP-dependent protein kinase (PKA) inhibitor
Serine/threonine-protein kinase AKT inhibitor
Peroxisome proliferator-activated receptor agonist
Neuronal acetylcholine receptor protein alpha-7 subunit partial agonist
Serotonin 3a (5-HT3a) receptor antagonist
T-lymphocyte activation antigen CD86 inhibitor
T-lymphocyte activation antigen CD80 inhibitor
Carbamoyl-phosphate synthase [ammonia], mitochondrial positive allosteric modulator
Vascular endothelial growth factor A antagonist
G protein-coupled receptor 44 antagonist
Neuronal acetylcholine receptor; alpha4/beta2 antagonist
Purine nucleoside phosphorylase inhibitor
Type I iodothyronine deiodinase (Type-I 5'deiodinase) (DIOI) (Type 1 DI) (5DI) inhibitor
Neuronal acetylcholine receptor protein alpha-7 subunit agonist
Neuronal acetylcholine receptor; alpha3/beta4 negative allosteric modulator
3-phosphoinositide dependent protein kinase-1 inhibitor
Serine/threonine-protein kinase Chk1 inhibitor
Sodium channel protein type X alpha subunit blocker
Nicotinic acetylcholine receptor alpha subunit agonist
Serotonin 2b (5-HT2b) receptor antagonist
Neuronal acetylcholine receptor; alpha3/beta4 antagonist
Glutamate receptor ionotropic AMPA positive allosteric modulator
Receptor protein-tyrosine kinase erbB-4 inhibitor
T cell surface glycoprotein CD3 inhibitor
Basic fibroblast growth factor inhibitor
Acidic fibroblast growth factor inhibitor
Glutamate [NMDA] receptor positive allosteric modulator
Serotonin 1d (5-HT1d) receptor antagonist
Serotonin 1a (5-HT1a) receptor antagonist
Serotonin 1b (5-HT1b) receptor antagonist
GABA A receptor alpha-1/beta-1/gamma-2 positive allosteric modulator
Slowly adapting pulmonary stretch receptor inhibitor
Peroxisome proliferator-activated receptor gamma antagonist
Influenza virus A matrix protein M2 inhibitor
Vascular endothelial growth factor receptor 2 antagonist
Tumor necrosis factor ligand superfamily member 13 inhibitor
Tumor necrosis factor ligand superfamily member 13B inhibitor
Heterotrimeric lymphotoxin LTa1b2 inhibitor
Tumor necrosis factor ligand superfamily member 14 inhibitor
Interleukin-5 receptor subunit alpha inhibitor
T cell surface glycoprotein CD3 cross-linking agent
B-lymphocyte antigen CD19 cross-linking agent
Tumor necrosis factor receptor superfamily member 8 inhibitor
Epithelial cell adhesion molecule binding agent
Insulin-like growth factor I receptor antagonist
Tumor necrosis factor receptor superfamily member 10B agonist
Tumor necrosis factor receptor superfamily member 5 inhibitor
Tumor necrosis factor receptor superfamily member 12A agonist
Transforming growth factor beta-3 inhibitor
Transforming growth factor beta-2 inhibitor
Transforming growth factor beta-1 inhibitor
Interleukin-1 beta negative allosteric modulator
Transmembrane glycoprotein NMB binding agent
Platelet-derived growth factor receptor alpha antagonist
T-cell surface glycoprotein CD3 epsilon chain other
Tumor necrosis factor receptor superfamily member 9 agonist
GABA receptor alpha-2 subunit positive allosteric modulator
GABA receptor alpha-3 subunit positive allosteric modulator
Cannabinoid CB1 receptor inverse agonist
Cytotoxic T-lymphocyte protein 4 inhibitor
Synaptic vesicle glycoprotein 2A modulator
Cystic fibrosis transmembrane conductance regulator positive modulator
Sodium/glucose cotransporter 2 inhibitor
Serine/threonine-protein kinase PIM inhibitor
Tyrosine-protein kinase receptor UFO inhibitor
Serine/threonine-protein kinase WEE1 inhibitor
Free fatty acid receptor 1 positive allosteric modulator
Neuropeptide Y receptor type 5 antagonist
Serotonin 4 (5-HT4) receptor partial agonist
Nicotinic acetylcholine receptor agonist
Killer cell immunoglobulin-like receptor 2DL2 inhibitor
Killer cell immunoglobulin-like receptor 2DL3 inhibitor
Killer cell immunoglobulin-like receptor 2DL1 inhibitor
Mucosal addressin cell adhesion molecule-1 inhibitor
Parathyroid hormone-related protein inhibitor
Vascular endothelial growth factor receptor 3 inhibitor
Calcitonin gene-related peptide type 1 receptor agonist
Amylin receptor AMY1, CALCR/RAMP1 agonist
Tumor necrosis factor receptor superfamily member 8 agonist
High affinity immunoglobulin gamma Fc receptor I other
Receptor protein-tyrosine kinase erbB-2 other
Serine/threonine-protein kinase receptor R3 inhibitor
Monocyte differentiation antigen CD14 inhibitor
C-C chemokine receptor type 2 antagonist
Connective tissue growth factor inhibitor
Epidermal growth factor-like protein 7 inhibitor
Receptor tyrosine-protein kinase erbB-3 antagonist
Receptor tyrosine-protein kinase erbB-3 inhibitor
Telomerase reverse transcriptase inhibitor
Epidermal growth factor receptor erbB1 antagonist
Kelch-like ECH-associated protein 1 inhibitor
Nucleotide-binding oligomerization domain-containing protein 2 other
Proteinase-activated receptor 1 antagonist
Induced myeloid leukemia cell differentiation protein Mcl-1 inhibitor
Amine oxidase, copper containing inhibitor
5-lipoxygenase activating protein inhibitor
Vitamin K-dependent gamma-carboxylase inhibitor
Synaptosomal-associated protein 25 inhibitor
Glucagon-like peptide 2 receptor agonist
Neural cell adhesion molecule 1 binding agent
Growth/differentiation factor 2 inhibitor
Serine/threonine-protein kinase PLK4 inhibitor
Group X secretory phospholipase A2 inhibitor
Microsomal triglyceride transfer protein inhibitor
Breakpoint cluster region protein inhibitor
Myeloid cell surface antigen CD33 other
Immunoglobulin epsilon Fc receptor antagonist
Leukocyte adhesion glycoprotein LFA-1 alpha inhibitor
Heat shock cognate 71 kDa protein inhibitor
Granulocyte-macrophage colony-stimulating factor inhibitor
HLA class II histocompatibility antigen, DRB1-10 beta chain other
Intercellular adhesion molecule-1 antagonist
T-cell differentiation antigen CD6 binding agent
Carcinoembryonic antigen-related cell adhesion molecule 5 other
Vascular endothelial growth factor receptor 1 and 2 (Flt-1 and KDR) agonist
Tumor necrosis factor receptor superfamily member 8 other
Sulfonylurea receptors; K-ATP channels opener
Muscarinic acetylcholine receptor antagonist
Neuronal acetylcholine receptor; alpha3/beta4 partial agonist
Platelet-derived growth factor receptor alpha inhibitor
Lanosterol 14-alpha demethylase inhibitor
Cystic fibrosis transmembrane conductance regulator stabiliser
HLA class II histocompatibility antigen, DRB1-15 beta chain modulator
Vascular endothelial growth factor receptor 1 antagonist
Dopamine receptors; D2 & D3 partial agonist
Integrin alpha-L/beta-2 (LFA-1) antagonist
Tumor necrosis factor receptor superfamily member 5 partial agonist
Metabotropic glutamate receptor 2 modulator
Metabotropic glutamate receptor 3 modulator
Cystic fibrosis transmembrane conductance regulator inhibitor
Neuronal acetylcholine receptor; alpha9/alpha10 antagonist
Growth/differentiation factor 8 inhibitor
Platelet activating factor receptor antagonist
Interleukin-4 receptor subunit alpha antagonist
Voltage-sensitive sodium channel alpha-subunit blocker
Tumor necrosis factor ligand superfamily member 4 inhibitor
Interleukin-6 receptor alpha subunit antagonist
5,6-dihydroxyindole-2-carboxylic acid oxidase other
T-cell surface glycoprotein CD3 epsilon chain inhibitor
C-C chemokine receptor type 1 antagonist
C-C chemokine receptor type 9 antagonist
Proteinase-activated receptor 1 inhibitor
Metabotropic glutamate receptor 5 modulator
Diacylglycerol O-acyltransferase 1 inhibitor
Platelet-derived growth factor receptor agonist
Glutamate receptor ionotropic AMPA antagonist
LDL-associated phospholipase A2 inhibitor
T-cell surface antigen CD4 negative modulator
Myelin-associated glycoprotein inhibitor
Interleukin-2 receptor alpha chain binding agent
Gamma-amino-N-butyrate transaminase inhibitor
T-cell surface glycoprotein CD5 binding agent
GABA receptor beta-3 subunit positive allosteric modulator
Granulocyte-macrophage colony-stimulating factor receptor agonist
UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitor
Glutamate receptor ionotropic kainate antagonist
HLA-DR antigens-associated invariant chain antagonist
Hepatocyte growth factor receptor antagonist
Interleukin-13 receptor subunit alpha-2 binding agent
Interleukin-13 receptor subunit alpha-1, Interleukin-4 receptor subunit alpha binding agent
GABA-A receptor; benzodiazepine site partial agonist
GABA-A receptor; benzodiazepine site inverse agonist
Soluble guanylate cyclase positive allosteric modulator
Peroxisome proliferator-activated receptor gamma partial agonist
Glutamate receptor ionotropic kainate 1 antagonist
Interleukin-2 receptor alpha chain antagonist
Vascular endothelial growth factor C inhibitor
Vascular endothelial growth factor B inhibitor
Programmed cell death protein 1 inhibitor
Lymphocyte differentiation antigen CD38 inhibitor
Heat-stable enterotoxin receptor agonist
Serotonin 2a (5-HT2a) receptor inverse agonist
Sodium/glucose cotransporter 1 inhibitor
Fast skeletal troponin complex activator
3-beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II inhibitor
Serine/threonine-protein kinase PAK 4 inhibitor
Metabotropic glutamate receptor 5 antagonist
Platelet-derived growth factor subunit B inhibitor
Programmed cell death 1 ligand 1 inhibitor
RAF serine/threonine protein kinase inhibitor
Cystic fibrosis transmembrane conductance regulator activator
MAP kinase-activated protein kinase 5 inhibitor
Neuronal acetylcholine receptor; alpha3/beta4 agonist
Sodium channel protein type IX alpha subunit blocker
Serine/threonine-protein kinase Chk2 inhibitor
Glutamate [NMDA] receptor partial agonist
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 inhibitor
Ribosomal protein S6 kinase (P70S6K) inhibitor
C-X-C chemokine receptor type 4 antagonist
Dual specificity protein kinase TTK inhibitor
Peroxisome proliferator-activated receptor delta agonist
MAP kinase-activated protein kinase 2 inhibitor
Serine/threonine-protein kinase AKT3 inhibitor
Metabotropic glutamate receptor 5 negative allosteric modulator
Serine/threonine-protein kinase AKT2 inhibitor
Neurotrophic tyrosine kinase receptor inhibitor
Cell division cycle 7-related protein kinase inhibitor
C5a anaphylatoxin chemotactic receptor antagonist
Sodium channel protein type XI alpha subunit blocker
Serine/threonine-protein kinase A-Raf inhibitor
Voltage-gated calcium channel alpha2/delta subunit 1 modulator
Voltage-gated calcium channel alpha2/delta subunit 2 modulator
Fibroblast growth factor receptor 4 inhibitor
Tyrosine-protein kinase receptor Tie-1 inhibitor
Dual specificity mitogen-activated protein kinase kinase; MEK1/2 inhibitor
Mitogen-activated protein kinase kinase kinase 5 inhibitor
Epithelial cell adhesion molecule inhibitor
Thyrotropin-releasing hormone receptor agonist
P2X purinoceptor 7 negative allosteric modulator
Sphingosine 1-phosphate receptor modulator
Leukocyte adhesion molecule-1 antagonist
Transient receptor potential cation channel subfamily V member 4 antagonist
Neuronal acetylcholine receptor protein alpha-7 subunit modulator
Vascular endothelial growth factor A binding agent
Transient receptor potential cation channel subfamily M member 8 agonist
GABA-A receptor; benzodiazepine site positive allosteric modulator
Transient receptor potential cation channel subfamily A member 1 antagonist
Transient receptor potential cation channel subfamily V member 3 antagonist
Neuronal acetylcholine receptor; alpha4/beta2 modulator
Atrial natriuretic peptide receptor A agonist
ATP-binding cassette sub-family A member 1 inhibitor
Epidermal growth factor receptor erbB1 other
Intermediate conductance calcium-activated potassium channel protein 4 opener
Transient receptor potential cation channel subfamily A member 1 opener
Transient receptor potential cation channel subfamily M member 8 opener
Cannabinoid CB1 receptor Negative allosteric modulator
Discoidin domain-containing receptor 2 inhibitor
Intercellular adhesion molecule 3 inhibitor
GABA-A receptor; agonist GABA site agonist
Sphingosine 1-phosphate receptor Edg-8 agonist
Protein tyrosine kinase 2 beta inhibitor
C-type lectin domain family 4 member C inhibitor
Calcitonin gene-related peptide_UNCURATED inhibitor
Receptor protein-tyrosine kinase erbB-2 binding agent
Amylin receptor AMY2; CALCR/RAMP2 agonist
Amylin receptor AMY3; CALCR/RAMP3 agonist