467899
constant: false
units: 993833
value: NaN
name: i_H
type: Parameter

467837
constant: false
units: dimensionless
value: 0.0
name: m
type: Parameter

467776
constant: true
units: 993858
value: 0.1
name: g_T
type: Parameter

467919
constant: true
units: 993785
value: 10.0
name: i_stimStart
type: Parameter

467890
constant: true
units: 993785
value: NaN
name: time
type: Parameter

467827
constant: true
units: 993809
value: 3.0
name: sigma_h
type: Parameter

467806
constant: false
units: dimensionless
value: NaN
name: h_infinity
type: Parameter

993931
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

467704
constant: false
units: dimensionless
value: 0.981
name: h
type: Parameter

467695
constant: true
units: 993882
value: 0.04
name: C
type: Parameter

467861
constant: true
units: 993785
value: 1.0
name: tau_z
type: Parameter

467780
constant: true
units: 993785
value: NaN
name: time
type: Parameter

993882
unit: 993894
name: uF
type: SBMLUnitsDef

467746
constant: true
units: 993809
value: 4.1
name: sigma_m
type: Parameter

467911
constant: true
units: 993809
value: 70.0
name: theta_1
type: Parameter

467870
constant: false
units: dimensionless
value: 0.057
name: m
type: Parameter

467904
constant: true
units: 993809
value: NaN
name: V
type: Parameter

467889
constant: true
units: 993809
value: NaN
name: V
type: Parameter

467842
constant: true
units: 993785
value: 10.0
name: tau_m
type: Parameter

993858
unit: 993870
name: uS
type: SBMLUnitsDef

467714
constant: false
units: dimensionless
value: NaN
name: h_infinity
type: Parameter

467789
constant: true
units: 993809
value: 70.0
name: sigma_2
type: Parameter

467794
constant: true
units: 993809
value: NaN
name: V
type: Parameter

467756
constant: true
units: 993785
value: NaN
name: time
type: Parameter

467857
constant: true
units: 993967
value: -500.0
name: K1
type: Parameter

467812
constant: true
units: 993785
value: NaN
name: time
type: Parameter

467851
constant: true
units: 993833
value: NaN
name: i_T
type: Parameter

467880
constant: true
units: 993809
value: 40.0
name: theta_1
type: Parameter

993906
unit: 993931
unit: 993918
name: uM
type: SBMLUnitsDef

467777
constant: true
units: 993809
value: 40.0
name: E_Ca
type: Parameter

467830
constant: false
units: dimensionless
value: NaN
name: h_infinity
type: Parameter

467819
constant: false
units: dimensionless
value: NaN
name: m_infinity
type: Parameter

467828
constant: true
units: 993785
value: 25.0
name: tau_h
type: Parameter

467840
constant: true
units: 993809
value: 3.0
name: sigma_m
type: Parameter

993979
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

467767
constant: false
units: 993785
value: NaN
name: tau_n
type: Parameter

467705
constant: true
units: 993809
value: 44.1
name: theta_h
type: Parameter

467848
constant: true
units: 993809
value: NaN
name: V
type: Parameter

467910
constant: true
units: 993809
value: 5.3
name: sigma_m
type: Parameter

993845
exponent: 1.0
scale: -9
multipler: 1.0
kind: AMPERE
type: SBMLUnit

467860
constant: false
units: 993906
value: 0.0604
name: Ca_conc
type: Parameter

467747
constant: true
units: 993785
value: 0.1
name: tau_m
type: Parameter

467725
constant: false
units: dimensionless
value: NaN
name: m_infinity
type: Parameter

467788
constant: true
units: 993809
value: 25.0
name: sigma_1
type: Parameter

994016
unit: 994028
name: time
type: SBMLUnitsDef

467831
constant: false
units: 993833
value: NaN
name: i_P
type: Parameter

467881
constant: true
units: 993809
value: 74.0
name: theta_2
type: Parameter

467858
constant: true
units: 993943
value: 0.04
name: K2
type: Parameter

467905
constant: true
units: 993785
value: NaN
name: time
type: Parameter

467818
constant: true
units: 993785
value: 5.0
name: tau_m
type: Parameter

467864
constant: false
units: 993833
value: NaN
name: i_A
type: Parameter

467825
constant: true
units: 993809
value: 70.0
name: theta_h
type: Parameter

467839
constant: true
units: 993809
value: 17.0
name: theta_m
type: Parameter

994004
exponent: -1.0
scale: -9
multipler: 1.0
kind: COULOMB
type: SBMLUnit

467913
constant: true
units: 993809
value: 11.0
name: sigma_1
type: Parameter

467726
constant: false
units: 993833
value: NaN
name: i_NaP
type: Parameter

467845
constant: false
units: 993833
value: NaN
name: i_SK
type: Parameter

467902
constant: true
units: 993809
value: -38.8
name: E_H
type: Parameter

467782
constant: false
units: dimensionless
value: 0.001
name: m
type: Parameter

467863
constant: false
units: dimensionless
value: NaN
name: z_infinity
type: Parameter

467800
constant: true
units: 993809
value: 7.0
name: sigma_h
type: Parameter

467744
constant: true
units: 993809
value: 47.1
name: theta_m
type: Parameter

993894
exponent: 1.0
scale: -9
multipler: 1.0
kind: FARAD
type: SBMLUnit

467711
constant: true
units: 993809
value: 25.0
name: sigma_2
type: Parameter

467810
constant: true
units: 993809
value: NaN
name: V
type: Parameter

467896
constant: true
units: 993785
value: 20.0
name: tau_h
type: Parameter

467792
constant: false
units: dimensionless
value: NaN
name: m_infinity
type: Parameter

467877
constant: true
units: 993809
value: 27.0
name: theta_m
type: Parameter

467758
constant: false
units: dimensionless
value: 0.158
name: n
type: Parameter

993967
unit: 994004
unit: 993991
unit: 993979
name: uM_per_nanocoulomb
type: SBMLUnitsDef

467779
constant: true
units: 993809
value: NaN
name: V
type: Parameter

467898
constant: false
units: dimensionless
value: NaN
name: h_infinity
type: Parameter

467707
constant: true
units: 993809
value: 7.0
name: sigma_h
type: Parameter

467770
constant: false
units: 993833
value: NaN
name: i_leak
type: Parameter

467696
constant: false
units: 993833
value: NaN
name: i_Na
type: Parameter

467807
constant: false
units: 993833
value: NaN
name: i_N
type: Parameter

467765
constant: true
units: 993809
value: 50.0
name: sigma_2
type: Parameter

993918
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

467843
constant: false
units: dimensionless
value: NaN
name: m_infinity
type: Parameter

993797
exponent: 1.0
scale: -3
multipler: 1.0
kind: SECOND
type: SBMLUnit

467764
constant: true
units: 993809
value: 40.0
name: sigma_1
type: Parameter

467846
constant: true
units: 993858
value: 0.3
name: g_SK
type: Parameter

467750
constant: false
units: 993833
value: NaN
name: i_K
type: Parameter

467922
constant: true
units: 993833
value: 10.0
name: i_stimAmplitude
type: Parameter

467713
constant: false
units: 993785
value: NaN
name: tau_h
type: Parameter

467791
constant: false
units: 993785
value: NaN
name: tau_m
type: Parameter

993833
unit: 993845
name: nanoA
type: SBMLUnitsDef

467710
constant: true
units: 993809
value: 4.0
name: sigma_1
type: Parameter

467759
constant: true
units: 993809
value: 30.0
name: theta_n
type: Parameter

467883
constant: true
units: 993809
value: 5.0
name: sigma_1
type: Parameter

467878
constant: true
units: 993809
value: 16.0
name: sigma_m
type: Parameter

993809
unit: 993821
name: millivolt
type: SBMLUnitsDef

467884
constant: true
units: 993809
value: 7.5
name: sigma_2
type: Parameter

467723
constant: true
units: 993785
value: 0.1
name: tau_m
type: Parameter

467741
constant: true
units: 993785
value: NaN
name: time
type: Parameter

467749
constant: false
units: dimensionless
value: NaN
name: m_infinity
type: Parameter

467771
constant: true
units: 993858
value: 0.005
name: g_leak
type: Parameter

467866
constant: true
units: 993858
value: 1.0
name: g_A
type: Parameter

993991
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

467833
constant: true
units: 993858
value: 0.05
name: g_P
type: Parameter

467761
constant: true
units: 993809
value: 25.0
name: sigma_n
type: Parameter

467816
constant: true
units: 993809
value: 6.0
name: sigma_m
type: Parameter

467908
constant: true
units: 993809
value: 79.8
name: theta_m
type: Parameter

467708
constant: true
units: 993809
value: 35.0
name: theta_1
type: Parameter

467728
constant: true
units: 993858
value: 0.05
name: g_NaP
type: Parameter

467701
constant: true
units: 993809
value: NaN
name: V
type: Parameter

467722
constant: true
units: 993809
value: 8.5
name: sigma_m
type: Parameter

467824
constant: false
units: dimensionless
value: 0.649
name: h
type: Parameter

467809
constant: true
units: 993858
value: 0.05
name: g_N
type: Parameter

993821
exponent: 1.0
scale: -3
multipler: 1.0
kind: VOLT
type: SBMLUnit

467895
constant: true
units: 993809
value: 11.0
name: sigma_h
type: Parameter

467698
constant: true
units: 993858
value: 0.7
name: g_Na
type: Parameter

467901
constant: true
units: 993858
value: 0.005
name: g_H
type: Parameter

467855
constant: false
units: dimensionless
value: 0.0
name: z
type: Parameter

467834
constant: true
units: 993809
value: NaN
name: V
type: Parameter

467752
constant: true
units: 993858
value: 1.3
name: g_K
type: Parameter

993785
unit: 993797
name: millisecond
type: SBMLUnitsDef

467738
constant: false
units: dimensionless
value: NaN
name: h_infinity
type: Parameter

467914
constant: false
units: 993785
value: NaN
name: tau_m
type: Parameter

467762
constant: true
units: 993809
value: 30.0
name: theta_1
type: Parameter

467798
constant: true
units: 993809
value: 70.1
name: theta_h
type: Parameter

467732
constant: false
units: dimensionless
value: 0.797
name: h
type: Parameter

467815
constant: true
units: 993809
value: 30.0
name: theta_m
type: Parameter

467731
constant: true
units: 993785
value: NaN
name: time
type: Parameter

467797
constant: false
units: dimensionless
value: 0.562
name: h
type: Parameter

467729
constant: true
units: 993809
value: NaN
name: V
type: Parameter

467920
constant: true
units: 993785
value: 11.0
name: i_stimEnd
type: Parameter

467801
constant: true
units: 993809
value: 70.0
name: theta_1
type: Parameter

467743
constant: false
units: dimensionless
value: 0.002
name: m
type: Parameter

467699
constant: true
units: 993809
value: 60.0
name: E_Na
type: Parameter

993955
exponent: -1.0
scale: -3
multipler: 1.0
kind: SECOND
type: SBMLUnit

467886
constant: false
units: 993785
value: NaN
name: tau_m
type: Parameter

467719
constant: false
units: dimensionless
value: 0.015
name: m
type: Parameter

467783
constant: true
units: 993809
value: 38.0
name: theta_m
type: Parameter

467821
constant: true
units: 993809
value: NaN
name: V
type: Parameter

467773
constant: true
units: 993809
value: -50.0
name: E_leak
type: Parameter

467768
constant: false
units: dimensionless
value: NaN
name: n_infinity
type: Parameter

467892
constant: false
units: dimensionless
value: 0.287
name: h
type: Parameter

467917
constant: false
units: 993833
value: NaN
name: i_app
type: Parameter

467702
constant: true
units: 993785
value: NaN
name: time
type: Parameter

467735
constant: true
units: 993809
value: 5.0
name: sigma_h
type: Parameter

993870
exponent: 1.0
scale: -6
multipler: 1.0
kind: SIEMENS
type: SBMLUnit

467854
constant: true
units: 993833
value: NaN
name: i_P
type: Parameter

467753
constant: true
units: 993809
value: -80.0
name: E_K
type: Parameter

467737
constant: true
units: 993785
value: 150.0
name: tau_h
type: Parameter

MODEL7980735163
parameter: 467877
parameter: 467710
parameter: 467843
parameter: 467922
rule: 467691
rule: 467649
parameter: 467825
parameter: 467870
parameter: 467756
parameter: 467889
parameter: 467738
parameter: 467722
parameter: 467801
parameter: 467789
parameter: 467855
parameter: 467704
rule: 467637
length unit: length
parameter: 467890
parameter: 467837
parameter: 467776
units def: 993809
parameter: 467768
parameter: 467782
parameter: 467734
curated: false
parameter: 467867
parameter: 467830
parameter: 467857
parameter: 467716
parameter: 467849
rule: 467683
parameter: 467902
units def: 993833
parameter: 467884
rule: 467668
is described by: http://identifiers.org/pubmed/15653786
parameter: 467750
parameter: 467917
parameter: 467901
parameter: 467883
parameter: 467728
parameter: 467783
rule: 467650
rule: 467671
parameter: 467896
parameter: 467696
parameter: 467762
parameter: 467895
parameter: 467795
units def: 994016
parameter: 467729
parameter: 467774
parameter: 467907
parameter: 467743
rule: 467685
parameter: 467702
parameter: 467842
rule: 467692
parameter: 467824
rule: 467652
parameter: 467755
rule: 467673
parameter: 467737
notes: This a model from the article: Ionic current model of a hypoglossal motoneuron. Purvis LK, Butera RJ. J Neurophysiol. 2005:93(2):723-33. 18068197 , Abstract: We have developed a single-compartment, electrophysiological, hypoglossal motoneuron (HM) model based primarily on experimental data from neonatal rat HMs. The model is able to reproduce the fine features of the HM action potential: the fast afterhyperpolarization, the afterdepolarization, and the medium-duration afterhyperpolarization (mAHP). The model also reproduces the repetitive firing properties seen in neonatal HMs and replicates the neuron's response to pharmacological experiments. The model was used to study the role of specific ionic currents in HM firing and how variations in the densities of these currents may account for age-dependent changes in excitability seen in HMs. By varying the density of a fast inactivating calcium current, the model alternates between accelerating and adapting firing patterns. Modeling the age-dependent increase in H current density accounts for the decrease in mAHP duration observed experimentally, but does not fully account for the decrease in input resistance. An increase in the density of the voltage-dependent potassium currents and the H current is required to account for the decrease in input resistance. These changes also account for the age-dependent decrease in action potential duration. This model was taken from the CellML repository and automatically converted to SBML. The original model was: purvis, butera, (2005) - version03 The original CellML model was created by: Nunns, Geoffrey, Rogan gnunns1@jhem.jhu.edu The University of Auckland Auckland Bioengineering Institute This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been ded…
parameter: 467800
parameter: 467854
parameter: 467788
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type: SBMLModel
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parameter: 467767
parameter: 467749
parameter: 467812
parameter: 467866
parameter: 467848
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467716
constant: true
units: 993809
value: NaN
name: V
type: Parameter

467887
constant: false
units: dimensionless
value: NaN
name: m_infinity
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467804
constant: false
units: 993785
value: NaN
name: tau_h
type: Parameter

467720
constant: true
units: 993809
value: 36.0
name: theta_m
type: Parameter

467786
constant: true
units: 993809
value: 28.0
name: theta_1
type: Parameter

467849
constant: true
units: 993785
value: NaN
name: time
type: Parameter

467822
constant: true
units: 993785
value: NaN
name: time
type: Parameter

467867
constant: true
units: 993809
value: NaN
name: V
type: Parameter

467740
constant: true
units: 993809
value: NaN
name: V
type: Parameter

994028
exponent: 1.0
scale: -3
multipler: 1.0
kind: SECOND
type: SBMLUnit

467893
constant: true
units: 993809
value: 80.0
name: theta_h
type: Parameter

467869
constant: true
units: 993785
value: NaN
name: time
type: Parameter

467916
constant: false
units: dimensionless
value: NaN
name: m_infinity
type: Parameter

467774
constant: false
units: 993833
value: NaN
name: i_T
type: Parameter

467734
constant: true
units: 993809
value: 65.0
name: theta_h
type: Parameter

467836
constant: true
units: 993785
value: NaN
name: time
type: Parameter

467907
constant: false
units: dimensionless
value: 0.182
name: m
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467755
constant: true
units: 993809
value: NaN
name: V
type: Parameter

467852
constant: true
units: 993833
value: NaN
name: i_N
type: Parameter

467693
constant: false
units: 993809
value: -71.847
name: V
type: Parameter

993943
unit: 993955
name: per_ms
type: SBMLUnitsDef

467717
constant: true
units: 993785
value: NaN
name: time
type: Parameter

467813
constant: false
units: dimensionless
value: 0.001
name: m
type: Parameter

467795
constant: true
units: 993785
value: NaN
name: time
type: Parameter

467620
constant: true
units: litre
size: 1.0
spatial dimensions: 3.0
type: Compartment

467785
constant: true
units: 993809
value: 5.0
name: sigma_m
type: Parameter

467803
constant: true
units: 993809
value: 65.0
name: sigma_1
type: Parameter