Complex(Grb2_br_@early end.EGFR_br_Y1068/1086P/c-Cbl_br_@EGFR.Y1045P)
Complex(Grb2_br_@EGFR._br_Y1068/1086P/PAK1_br_@GTP-Rac_br_or Cdc42)
active ADAMs: PMID: 10622253 PMID: 15337756
EGF / TGF_alpha_ / HB-EGF_br_amphiregulin / biregulin_br_betacellulin / epiregulin
Complex(NRG-1 biregulin_br_NRG-2 / heregulin/active_br_ErbB3)
autophosphorylation: PMID: 14963038 PMID: 10704819
hydrolysis: PMID: 14663478 beta2-chimaerin (RacGAP): PMID: 1903516 PMID: 8496137 PMID: 11278894
ligand: PMID: 10214951 PMID: 11252954 PMID: 10880430 sutophosphorylation: PMID: 10880430
Complex(active_br_ErbB4/HB-EGF / NRG-1 / 2 / 3 / 4_br_betacellulin / epiregulin)
active Rin1@GTP+Ras: PMID: 11703925 GDP-GTP exchange: PMID: 11703925
RasGAP@EGFR.Y992P:PMID: 14663478 PMID: 10740269 hydrolysis: PMID: 14663478
active EGFR: PMID: 12127568 PMID: 7532293
Complex(GDP/G_alpha_ _sub_s/G_beta/G_gamma)
Complex(ErbB1_br_ligand/early end._br_EGFR)
PI3 PMID: 4 PMID: 5P3: PMID: 12829245 PMID: 15276015 autophosphorylation: PMID: 10455013
Complex(Grb2_br_@early end.EGFR_br_Y1068/1086P/active_br_SOS1)
active MKK3: PMID: 8622669 active MKK4: PMID: 8622669 PMID: 9582321 active MKK6: PMID: 8622669
Complex(GDP/G_alpha_ _sub_q/G_beta/G_gamma)
early end.EGFR: PMID: 15210722 c-Cbl: PMID: 10635327
active adenylyl cyclase: PMID: 14519441 active adenylyl cyclase II: PMID: 14519441
early end.EGFR: PMID: 12006650 PMID: 11084343
Galpha s: PMID: 14519441 Galpha i: PMID: 14519441
autophosphorylation: PMID: 12829245 active PDK2: PMID: 12829245
active ERK1: PMID: 15136564 active ERK2: PMID: 15136564 active JNK: PMID: 15136564
autophosphorylation: PMID: 10428774 PMID: 10856237
active EGFR: PMID: 8378775 PMID: 9287210 active c-Src: PMID: 10358079
Complex(Grb2_br_@early end.EGFR_br_Y1068/1086P/SOS1)
Complex(GDP/G_alpha_ _sub_i/G_beta/G_gamma)
autophosphorylation: PMID: 11950587 PMID: 10551809
Complex(GDP/G_alpha_ _sub_12/13/G_beta/G_gamma)
unidentified S/T kinase(s): PMID: 12551923
phosphorylation: PMID: 8205620 nuc.RSK: PMID: 9528766 PMID: 9770464
phosphatidic acid: PMID: 1313792 PMID: 12790797
This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not.. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
active PLCbeta: PMID: 12790797 active truncated PLCbeta: PMID: 12790797 PLCgamma: PMID: 10579907