http://identifiers.org/biomodels.db/MODEL1303260018#_56b227a8_cefc_48d9_bc12_33b89de8ca17
units: dimensionless
value: 100.0
type: LocalParameter

meta PDC PDC6
name: pyruvate decarboxylase [PDC6]
reversible: false
is version of: GO:0004737
is version of: http://identifiers.org/ec-code/4.1.1.1
is: R00636
type: Reaction
modifier: MODEL1303260018#
is: SBO:0000176
fast: false

http://identifiers.org/biomodels.db/MODEL1303260018#e87d9b6b_8cee_4ebf_8829_072758b4609e
value: 8.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_2667a6b6_f9ec_4ecd_aca8_da6c2d8793a8
value: 0.003
type: LocalParameter

meta PDC1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.06781077822834
initial amount: NaN
in compartment: meta cell
name: PDC1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#f072c1a0_e513_4b1d_be02_711eda68faf5
stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#b7c654d2_1688_454d_9d1d_2ac8fb6ccfe7
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

meta ACE
has only substance units: false
is: CHEBI:30089
initial concentration: 223.000253398294
constant: true
name: acetate
in compartment: meta cell
type: Species
is: SBO:0000247
initial amount: NaN
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1303260018#_1b1a9ece_52a1_4920_8581_52965b728756
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_58f5ef63_45b5_4fe9_8991_8adbe5d88eaf
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_35048714_5616_430c_8781_2575289368b6
value: 0.17
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_834389f1_577c_4b2a_970a_0fbee1004f23
value: 0.865
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_890a2c59_df86_4809_bf84_5a853f31ffc5
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_49ce2752_662a_404e_b882_633e6d52b9b5
value: 0.65
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_51d329f6_7f07_4f32_b4c7_747338e44009
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

meta UGP
name: UDP glucose phosphorylase
type: Reaction
is version of: http://identifiers.org/ec-code/2.7.7.9
reversible: false
fast: false
modifier: MODEL1303260018#
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1303260018#_57770519_b7e5_40cc_b6a0_45c96007c8cb
stoichiometry: 1.0
species: meta UDP
type: SpeciesReference

meta PEP
boundary condition: false
has only substance units: false
is: CHEBI:18021
is: C00074
initial amount: NaN
name: phosphoenolpyruvate
in compartment: meta cell
constant: false
type: Species
is: SBO:0000247
initial concentration: 0.610005413358042

http://identifiers.org/biomodels.db/MODEL1303260018#_3b929fcd_bdca_48fc_88e8_2607bdd5e443
value: 0.19
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_749cb4bc_1044_4d59_8d11_11084d57a576
value: 0.023
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_50ea5506_7b82_460a_836a_6cba0a7fae46
value: 10.32
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_563099a1_e024_4095_bb25_6198c39e72da
value: 0.2
type: LocalParameter

meta TPS2
in compartment: meta cell
boundary condition: true
initial concentration: 0.00265985181347494
has only substance units: false
is: P31688
initial amount: NaN
is: SBO:0000252
is encoded by: S000002481
name: TPS2
constant: true
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#b1dc4096_6feb_491f_beb7_15e25cf34b4b
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_5c9073bf_4607_4bc7_8bc2_29b7928bd4f6
value: 1.0257
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#f6477a66_689a_4f8d_bb37_e98daf0afcc8
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#c8789725_faaa_4a8c_bdc5_5415a748f32a
value: 0.0995
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#ff48a0b3_d0e7_465a_8789_2e5265e94884
value: 0.783333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#ced1e7b5_b02f_4254_8540_c48c7c060086
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_7e5f780e_0359_4268_9a6b_546eaec481d7
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#ffca051a_6da5_44e3_9ac3_3d4b22781add
value: 0.9
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_37d09fcc_da9a_4f36_9ef1_d5d0852b162c
units: dimensionless
value: 0.0845
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#afe76c9c_ae45_4e25_97dd_e24c4d027c27
value: 30.0
type: LocalParameter

meta TPS1
name: TPS1
is: Q00764
constant: true
in compartment: meta cell
initial concentration: 0.00339248174237065
initial amount: NaN
is: SBO:0000252
type: Species
boundary condition: true
is encoded by: S000000330
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260018#e119909f_5998_4b15_8f12_87b3357fab60
stoichiometry: 1.0
species: meta UTP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#bc5eda3f_f38d_4ac3_9abd_ff1133a1b5e4
value: 35.1
type: LocalParameter

meta GPD
type: Reaction
fast: false
is: SBO:0000176
is: http://identifiers.org/ec-code/1.1.1.94
name: glycerol 3-phosphate dehydrogenase
modifier: MODEL1303260018#
is: R00842
reversible: true

meta PDC PDC5
is: R00636
fast: false
modifier: MODEL1303260018#
reversible: false
is version of: GO:0004737
type: Reaction
is: SBO:0000176
is version of: http://identifiers.org/ec-code/4.1.1.1
name: pyruvate decarboxylase [PDC5]

http://identifiers.org/biomodels.db/MODEL1303260018#_16a8ae46_dd14_46ae_8844_7b5ddfd35913
value: 0.495
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_33586259_58fd_4194_835d_2243011cf4ca
value: 6.82E-4
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_6f258b10_9aaf_4032_b81c_488154018c27
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_1f0959a2_55d0_4795_968b_261c878457f7
stoichiometry: 3.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_8dc0a11d_3c33_477d_b153_52e0ccc932bf
value: 0.023
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#e3653041_8b83_4993_9311_d76697b916f6
stoichiometry: 1.0
species: meta UDG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_30858e42_3e34_402d_86d4_60b20aefa436
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#cc8ce1b3_7fad_4bdf_9980_1a5c49a4ad7e
value: 0.243
type: LocalParameter

meta GPM1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.73000029889707
initial amount: NaN
in compartment: meta cell
name: GPM1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#_21fde91a_9c6e_4f52_9b0a_700be2b4e83d
value: 1.1
type: LocalParameter

meta F26bP
initial concentration: 0.003
type: Species
has only substance units: false
name: fructose 2,6-bisphosphate
constant: true
is: CHEBI:28602
is: SBO:0000247
is: C00665
in compartment: meta cell
initial amount: NaN
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1303260018#_2809f8aa_a1d2_4aa3_ae9f_07af35cf70ae
value: 0.0106
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_26d582c8_a93c_496e_a2c4_e4ae4f1c564b
exponent: -1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260018#a00187ee_bae5_4cae_98e0_78457ce83c35
value: 0.92
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#ca85bda7_3ca7_4366_a93c_6891f1d53120
stoichiometry: 1.0
species: meta UDG
type: SpeciesReference

meta PYK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00606993527217899
initial amount: NaN
in compartment: meta cell
name: PYK2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#ab90bd47_b348_4965_a705_21741a98ae4a
value: 487.36
type: LocalParameter

meta G1P
constant: false
initial amount: NaN
boundary condition: false
is: CHEBI:16077
has only substance units: false
initial concentration: 0.539248506344921
type: Species
in compartment: meta cell
name: glucose 1-phosphate
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1303260018#a943f559_724a_4a12_8ee8_8c9b700ce457
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

meta PDC6
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00654086421106118
initial amount: NaN
in compartment: meta cell
name: PDC6
type: Species

meta P2G
constant: false
has only substance units: false
is: C00631
name: 2-phosphoglycerate
boundary condition: false
is: CHEBI:17835
is: SBO:0000247
type: Species
initial amount: NaN
in compartment: meta cell
initial concentration: 0.0677379081099344

meta P3G
type: Species
initial amount: NaN
is: SBO:0000247
is: C00197
initial concentration: 0.469825011134444
name: 3-phosphoglycerate
has only substance units: false
in compartment: meta cell
constant: false
is: CHEBI:17794
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1303260018#da5856d1_fffd_4d2d_9304_d334ee269571
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

meta GLY
in compartment: meta cell
constant: true
initial concentration: 0.15
has only substance units: false
type: Species
boundary condition: true
initial amount: NaN
is: SBO:0000247
is: C00116
is: CHEBI:17754
name: glycerol

W3 CDTF: Sun Nov 09 00:00:00 GMT 2008

http://identifiers.org/biomodels.db/MODEL1303260018#_8239425b_57d5_487a_ace9_d76d3a961130
value: 21.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_50904bd1_28ce_47ed_b63d_203cbd46d7a7
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260018#aa3f7c4c_ed66_470f_b84b_f05054a432c8
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_89e063c2_75a3_4053_bbe6_800ecb9db8bf
value: 13.2552
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_1f19c05a_8e90_4470_b6a3_d7fcc9b5ada3
name: per mM per second
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260018#_5158d08c_d2a4_4a66_bbe7_8120dce9c448
value: 0.49356
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#b226d329_5112_43c9_8292_039543677fa3
value: 1.5
type: LocalParameter

meta PFK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0390366215332091
initial amount: NaN
in compartment: meta cell
name: PFK2
type: Species

meta PDC5
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0123547443267676
initial amount: NaN
in compartment: meta cell
name: PDC5
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#ae404a03_539e_4074_be21_f6f32948894f
constant: true
units: dimensionless
value: 0.00533412710224736
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260018#_8a8858ec_84e5_42f3_a372_d0fa460f03dd
stoichiometry: 1.0
species: meta UDP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_89732ff9_bb6f_4987_842b_c2385bf36e7f
units: dimensionless
value: 10000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#d2e86983_ae7e_49ca_9466_c57d6771b281
constant: true
value: 1.59
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260018#_8b157c66_1699_463a_bbf8_5061e12a2e8a
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_23ac0b58_6274_41e2_8fd7_d68191d3c72c
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260018#c9215613_be91_44dc_b817_2aab55e93bc3
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_26a3e011_b3ba_4dd4_aa43_5fe92f76300b
value: 0.0745258294103764
type: LocalParameter

meta ENO ENO1
type: Reaction
is version of: GO:0004634
is: R00658
modifier: MODEL1303260018#
is version of: http://identifiers.org/ec-code/4.2.1.11
reversible: true
fast: false
name: enolase [ENO1]
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1303260018#a86932b9_72e4_461d_be93_cb6e7da9df9e
value: 1.41
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#edbdf12e_9926_40d3_b9db_21bc4084e685
units: dimensionless
value: 0.66
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#a317e48a_4049_40b6_8bca_35fc4296ad28
value: 1.99
type: LocalParameter

meta NAD
is: CHEBI:15846
boundary condition: false
type: Species
constant: false
in compartment: meta cell
has only substance units: false
name: NAD
is: SBO:0000247
is: C00003
initial amount: NaN
initial concentration: 1.50329030201531

http://identifiers.org/biomodels.db/MODEL1303260018#d3c77c2d_e4a3_4017_993a_f7520a2b6bc9
value: 2.0
type: LocalParameter

meta GAP
name: glyceraldehyde 3-phosphate
initial concentration: 0.315891028770503
is: C00118
boundary condition: false
constant: false
initial amount: NaN
is: CHEBI:29052
is: SBO:0000247
has only substance units: false
type: Species
in compartment: meta cell

meta ENO ENO2
is: SBO:0000176
is version of: http://identifiers.org/ec-code/4.2.1.11
name: enolase [ENO2]
type: Reaction
is: R00658
fast: false
modifier: MODEL1303260018#
reversible: true
is version of: GO:0004634

http://identifiers.org/biomodels.db/MODEL1303260018#ff982c81_4b97_4ec4_957e_9fd9c911b02a
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#e662e7b4_52f5_4053_be73_70bec08b4f89
units: dimensionless
value: 3200.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_6c649074_e649_417f_9f31_78972370b990
units: dimensionless
value: 0.0174
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_024c649a_f068_4685_b345_ec3158b0e256
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#f4cf6e5b_0418_4ba5_88af_7768c4215497
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

meta ATPase
is: SBO:0000176
reversible: false
fast: false
type: Reaction
modifier: MODEL1303260018#
is version of: GO:0016887
name: ATPase

http://identifiers.org/biomodels.db/MODEL1303260018#_28dcffe7_8190_4553_b173_4c9de8997e8d
value: 0.77
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_82adb6d9_47ce_4e31_8f72_81fb029ee014
value: 9.21
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#a786f101_6e37_4933_977b_00afe480fb59
constant: true
value: 6.022140000000001E20
name: Avogadro constant
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260018#_608eb296_98b2_4233_9043_391ad9823746
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_2da05961_3747_4fb0_89a3_d1afda0ae8ac
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta ENO2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.97444629317817
initial amount: NaN
in compartment: meta cell
name: ENO2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#ce39977c_80db_427f_9fe6_4083add5992c
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#ea842652_ba4c_4749_a880_1f24f64d0244
value: 0.73
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#fecc08fd_0456_4267_8214_2289bbab0940
value: 0.00554339592436782
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_1295d8f2_be39_411b_ab5f_d284621213fd
value: 0.909
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#b8cb36d9_f773_4314_8040_83175207506f
value: 0.23
type: LocalParameter

meta FBA
fast: false
modifier: MODEL1303260018#
name: fructosebisphosphate aldolase
type: Reaction
is version of: GO:0004332
is: R01068
is version of: http://identifiers.org/ec-code/4.1.2.13
reversible: true
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1303260018#_6f9471b6_e3f6_46c1_a48b_e071f3c427a2
units: dimensionless
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_11cf65a3_67dc_454f_bb66_45f4e12e7286
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_629f81e5_a8d4_440a_9384_da44af5c7ea8
value: 90.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_07b2390c_565f_4286_a8ba_fae60008be0c
stoichiometry: 1.0
species: meta TRH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_819e52ae_7b6d_4e6a_912f_a8067e5f5eed
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta ENO1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.686371954155832
initial amount: NaN
in compartment: meta cell
name: ENO1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#_3255d072_7007_47f0_8fb8_48b2c4f12cae
stoichiometry: 1.0
species: meta ACE
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_7bc530b7_1c81_4828_9903_0d123203b599
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_7b823821_8769_4c1f_88fb_38b323ebd30b
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#b38928d6_bd4b_4de8_a81a_12f8dcf21869
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_52110975_9d64_4976_a8e8_fab1679e172c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#ce037089_73d8_4e58_ae4e_2b3a3cfacf90
units: dimensionless
value: 0.19
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#f089fabd_c8dd_40ff_b5ae_7e1f9b070d06
stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#c803b8a1_85d3_42e6_bdf3_6e4040619997
value: 1.1
type: LocalParameter

meta TDH TDH1
is version of: GO:0004365
is version of: http://identifiers.org/ec-code/1.2.1.12
is: SBO:0000176
is: R01061
reversible: true
type: Reaction
modifier: MODEL1303260018#
fast: false
name: glyceraldehyde phosphate dehydrogenase [TDH1]

meta PFK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0467850299063124
initial amount: NaN
in compartment: meta cell
name: PFK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#_3a04e497_0f91_4380_85eb_4397f53fba76
stoichiometry: 1.0
species: meta G3P
type: SpeciesReference

meta AMP
in compartment: meta cell
is: CHEBI:16027
boundary condition: true
initial amount: NaN
initial concentration: 0.44
is: SBO:0000247
is: C00020
has only substance units: false
name: AMP
type: Species
constant: false

http://identifiers.org/biomodels.db/MODEL1303260018#_92aba4d8_085d_4f3c_a20c_faaa35f42064
name: per second
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260018#c4e5b78c_cb73_4827_933e_a1fee91f8b70
value: 4.139
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_286cce5a_6d9e_48c4_b45b_0f57c869515c
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_821cd729_dad5_453e_b6c4_deed5b831b51
stoichiometry: 1.0
species: meta EtOH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_8697ea1e_b7cd_48a0_aae7_4e157d4ebc07
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

meta ADP
is: CHEBI:16761
in compartment: meta cell
initial concentration: 1.29
constant: false
is: SBO:0000247
is: C00008
initial amount: NaN
boundary condition: false
type: Species
has only substance units: false
name: ADP

meta TDH TDH2
reversible: true
modifier: MODEL1303260018#
is: SBO:0000176
type: Reaction
is version of: http://identifiers.org/ec-code/1.2.1.12
name: glyceraldehyde phosphate dehydrogenase [TDH2]
fast: false
is: R01061
is version of: GO:0004365

meta HXK GLK1
reversible: true
type: Reaction
is version of: http://identifiers.org/ec-code/2.7.1.1
fast: false
name: hexokinase [GLK1]
is: SBO:0000176
is: R02848
is version of: GO:0004396
modifier: MODEL1303260018#

http://identifiers.org/biomodels.db/MODEL1303260018#_21e71f37_d14a_4a16_ba29_abd362e40969
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#e213fdc8_8e5a_4651_99ad_de57d41268ff
units: dimensionless
value: 5.12
type: LocalParameter

meta cell
is: GO:0005829
constant: true
size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

http://identifiers.org/biomodels.db/MODEL1303260018#d1403dbd_576c_4639_92bc_b3fecca805e4
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_6b81d398_734b_4e44_9888_7b340aa85bbc
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#ac3a95d4_bec3_4ed3_8454_123e08660902
value: 0.883333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#abe1ba89_e401_4436_9dd2_445b8c8df189
stoichiometry: 1.0
species: meta P2G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#bb78cb88_b37e_4e0f_882b_f9470a99717f
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_5195570a_8e6d_48a7_a8df_4a3b039d061e
value: 209.6
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#ce3e9248_7dfb_45ba_bba2_706c1baf0c26
value: 0.0721
type: LocalParameter

meta UTP
initial amount: NaN
constant: false
name: UTP
initial concentration: 0.6491
in compartment: meta cell
is: CHEBI:46398
has only substance units: false
is: SBO:0000247
boundary condition: false
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#e35e853d_c501_441a_a65d_9b1a206de6cd
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_257be9bc_adc1_4274_af14_7e112a04ef4b
value: 0.23
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#ce19a7d5_3768_4b43_a312_45de641e486b
value: 63.1
type: LocalParameter

meta PYK CDC19
modifier: MODEL1303260018#
is version of: http://identifiers.org/ec-code/2.7.1.40
is version of: GO:0004743
fast: false
type: Reaction
name: pyruvate kinase [CDC19]
is: R00200
reversible: true
is: SBO:0000176

meta UDP
constant: false
boundary condition: false
is: CHEBI:17659
in compartment: meta cell
initial concentration: 0.2815
has only substance units: false
is: SBO:0000247
type: Species
name: UDP
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260018#_9a22d790_4dc4_42b6_952b_49c2939fef8e
value: 4.8
type: LocalParameter

meta GPD1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00683511177089872
initial amount: NaN
in compartment: meta cell
name: GPD1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#_387ef114_64e8_436b_aa82_645aa6fbd288
units: dimensionless
value: 0.29
type: LocalParameter

meta succinate branch
fast: false
is: SBO:0000176
type: Reaction
modifier: MODEL1303260018#
reversible: false
is version of: GO:0006105
name: succinate branch

http://identifiers.org/biomodels.db/MODEL1303260018#_5c423a7d_2fca_4486_a7b6_e4474b5554e8
value: 2.4
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_3e1b813f_8b92_4482_b4f6_6b1274fa9740
stoichiometry: 1.0
species: meta P3G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_603e60f2_2644_4921_87a7_f9f5ea3c82c9
units: dimensionless
value: 0.45
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#ac17eca5_f909_4904_b8ab_3baa50c6e796
value: 1.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_2ea36c5b_ace1_4853_9128_343393cae01c
name: per mmol
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260018#bdde168f_f581_49f1_93eb_7f00add4d372
value: 0.195
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_84fa4323_2bc4_4159_8cc2_db86ab38490d
constant: false
units: dimensionless
value: NaN
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260018#_8ee727be_dd80_4888_b81c_a763501785de
value: 0.09
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_1a8c46c1_5366_456c_86a1_f91b81fb5fe4
value: 2.92
type: LocalParameter

meta GPD2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 7.93405666424228E-4
initial amount: NaN
in compartment: meta cell
name: GPD2
type: Species

meta GLCx
in compartment: meta extracellular
name: glucose
type: Species
is: SBO:0000247
is: CHEBI:4167
constant: true
initial amount: NaN
initial concentration: 74.0
boundary condition: true
has only substance units: false
is: C00031

http://identifiers.org/biomodels.db/MODEL1303260018#_9dbb319e_7d23_49d1_a02e_ca78b7f53494
value: 90.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_20d22893_90e6_428a_b364_b83f735a70f8
value: 0.0098
type: LocalParameter

meta FBA1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.33839465704882
initial amount: NaN
in compartment: meta cell
name: FBA1
type: Species

meta TPI1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.294357819645508
initial amount: NaN
in compartment: meta cell
name: TPI1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#_2348b2e2_56ca_4d68_8fc3_ef7f68870cd7
value: 4.58
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#f5f8544b_bc14_434c_b75b_a922c60486b6
value: 0.307
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_139f8353_97d4_4ee5_81ae_531e09eced76
value: 400.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#fa35f0ce_db85_45d8_8651_7c37899f8bd7
units: dimensionless
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_79722660_695a_40fc_a066_baa6caca623f
value: 12.14
type: LocalParameter

meta ATP
initial amount: NaN
is: SBO:0000247
boundary condition: false
has only substance units: false
is: CHEBI:15422
name: ATP
in compartment: meta cell
type: Species
constant: false
is: C00002
initial concentration: 4.29

http://identifiers.org/biomodels.db/MODEL1303260018#ac7e18e1_cc04_4b98_b002_4471e151b9f8
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#e94b4886_6c6a_43af_8983_b3f296fd32b5
value: 10.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_4a751c53_412a_46ce_ac48_9f789abd083b
value: 0.12762
type: LocalParameter

meta F6P
initial amount: NaN
initial concentration: 0.235441221891221
constant: false
boundary condition: false
type: Species
in compartment: meta cell
is: CHEBI:16084
is: SBO:0000247
has only substance units: false
name: fructose 6-phosphate
is: C05345

http://identifiers.org/biomodels.db/MODEL1303260018#_49580b1c_39c8_46a0_80ea_7f00a43bc693
value: 176.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_35081372_1cc8_4a8a_82c1_7271932c939d
units: dimensionless
value: 0.045
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#f3d24f5f_47f0_4bc7_8730_d41fa6c2df11
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260018#_98b7747b_4e69_444a_8a0b_78bbf6d95712
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_5c4cf266_28ae_4e4d_90eb_47fd81f4721a
stoichiometry: 1.0
species: meta G1P
type: SpeciesReference

meta HXT
reversible: true
is version of: GO:0015758
modifier: MODEL1303260018#
fast: false
type: Reaction
name: glucose transport
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1303260018#_64c8a232_7724_4986_abf0_177334a677e7
stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_8ca218d6_75a7_480e_ba55_c3817080726b
stoichiometry: 3.0
species: meta NADH
type: SpeciesReference

meta PDC PDC1
is: R00636
modifier: MODEL1303260018#
reversible: false
name: pyruvate decarboxylase [PDC1]
is version of: GO:0004737
fast: false
is version of: http://identifiers.org/ec-code/4.1.1.1
type: Reaction
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1303260018#_6e5aeac3_dc85_476e_8d69_6f4cd0170e50
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260018#_486d1a07_8e56_4f1e_9d54_5abf7bdb56b7
value: 30.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#a3f30ecb_1dfd_47f7_ac00_acfa0b9350a4
constant: true
value: 6.02
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260018#_301ab0bc_5de7_477d_9ea3_b2f218e8c908
value: 0.15
type: LocalParameter

meta DHAP
in compartment: meta cell
boundary condition: false
initial concentration: 1.1613768527467
constant: false
initial amount: NaN
is: SBO:0000247
is: CHEBI:16108
has only substance units: false
type: Species
is: C00111
name: dihydroxyacetone phosphate

http://identifiers.org/biomodels.db/MODEL1303260018#_61e928c1_81b5_4e72_9569_5c24024913f4
value: 1.11
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#fb0ce1b3_30a5_4238_8e11_34682e82f654
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_404cb718_e661_40ef_a2d5_0ef5649c1552
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_531b5f50_a6d8_4f6f_b2c2_a1766879a0fc
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_18174b48_44c0_43ed_ad31_39735a6b9b8b
value: 0.04
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_15852d2e_7e74_4f7b_8172_a33dbd7ebb16
value: 7.08
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#c37c24d4_751b_401b_92ef_553748c76bca
value: 2.33999999999999
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_1be3b1ac_e65c_4019_bef0_0c7ff75b1f45
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

meta GLK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0450869624419226
initial amount: NaN
in compartment: meta cell
name: GLK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#_1f843d6c_43e0_4711_b0e2_9b8f24679203
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta HXK HXK2
is version of: http://identifiers.org/ec-code/2.7.1.1
modifier: MODEL1303260018#
is: R02848
name: hexokinase [HXK2]
is: SBO:0000176
type: Reaction
fast: false
reversible: true
is version of: GO:0004396

http://identifiers.org/biomodels.db/MODEL1303260018#e6138357_9de8_492e_9733_8e6b0706f1cd
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta HXK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0167807457149784
initial amount: NaN
in compartment: meta cell
name: HXK1
type: Species

meta PGI
reversible: true
is: R00771
type: Reaction
is version of: GO:0004347
fast: false
name: phosphoglucose isomerase
modifier: MODEL1303260018#
is: SBO:0000176
is version of: http://identifiers.org/ec-code/5.3.1.9

http://identifiers.org/biomodels.db/MODEL1303260018#_0e99f564_3e89_481a_aec3_2c3cee1736cc
stoichiometry: 1.0
species: meta P2G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#a7e9b27c_8f11_48c9_81ce_c64fa9cf2745
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#ad0189a7_e484_4d91_9364_0834a093d7b9
units: dimensionless
value: 0.397
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#c29dda27_822a_436f_800d_f92856bccd1e
value: 1.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_6ed88a41_5ba7_4a58_8d79_a4f835b639f5
constant: true
units: dimensionless
value: 6500.0
type: Parameter

meta PGM1
boundary condition: true
initial concentration: 0.00326229546307459
type: Species
is: SBO:0000252
constant: true
in compartment: meta cell
is encoded by: S000001610
is: P33401
has only substance units: false
name: PGM1
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260018#_7932a897_836b_4a66_a29b_c736aa156df1
value: 17.0
type: LocalParameter

meta HXK HXK1
fast: false
is: R02848
is: SBO:0000176
reversible: true
is version of: GO:0004396
type: Reaction
is version of: http://identifiers.org/ec-code/2.7.1.1
modifier: MODEL1303260018#
name: hexokinase [HXK1]

http://identifiers.org/biomodels.db/MODEL1303260018#_589d18d0_0482_44fa_aeec_49864b6cd096
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_10f9c172_a977_4758_8ba6_26f31811d4eb
value: 20.146
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#f9912460_dae5_4c2c_b6c1_b8b47a548464
value: 0.111
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_54fbec4e_b0a9_4e47_aaf5_0bcd3bac56ac
constant: true
units: dimensionless
value: 6.7
type: Parameter

meta UGP1
is encoded by: S000001518
type: Species
initial concentration: 0.00620211419860714
is: P32861
boundary condition: true
has only substance units: false
in compartment: meta cell
name: UGP1
initial amount: NaN
is: SBO:0000252
constant: true

http://identifiers.org/biomodels.db/MODEL1303260018#_82337a5b_3f80_4df2_9c57_29eb7ac2a91d
value: 0.92
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#de7bd9ff_e0e4_4ad9_a8fc_609c41cbe88f
value: 0.93
type: LocalParameter

meta PGI1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.1382907072901
initial amount: NaN
in compartment: meta cell
name: PGI1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#f2c137a8_25aa_43eb_ae46_2a898bca609c
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

meta HXK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0613313539705155
initial amount: NaN
in compartment: meta cell
name: HXK2
type: Species

meta extracellular
is: GO:0005576
constant: true
size: 1.0
spatial dimensions: 3.0
name: extracellular
type: Compartment

http://identifiers.org/biomodels.db/MODEL1303260018#dc8d95ed_d9d3_424c_97d8_5246a277505b
value: 3.35
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#a0feca30_5ce7_4a2f_9e2c_23c48cdaeb0b
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

meta PGM2
has only substance units: false
name: PGM2
is: P37012
is encoded by: S000004711
initial amount: NaN
constant: true
in compartment: meta cell
boundary condition: true
type: Species
is: SBO:0000252
initial concentration: 0.00125868877176552

meta PGK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.257656912658955
initial amount: NaN
in compartment: meta cell
name: PGK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#c2f639df_394b_4045_aaaa_ed405b3d5457
units: dimensionless
value: 0.91
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_997f980c_2d18_48a4_a8a5_95174d4e4cd2
stoichiometry: 1.0
species: meta F6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#a2919328_beea_40e0_8e66_9eea8ede1276
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

meta F16bP
is: SBO:0000247
in compartment: meta cell
boundary condition: false
name: fructose 1,6-bisphosphate
initial concentration: 4.58321859006931
is: CHEBI:28013
has only substance units: false
initial amount: NaN
is: C05378
type: Species
constant: false

meta TDH3
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 4.20440474648547
initial amount: NaN
in compartment: meta cell
name: TDH3
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#be60bfa5_0c2c_4763_8864_2b686ca0651c
value: 0.09
type: LocalParameter

meta GLC
initial amount: NaN
is: C00031
initial concentration: 6.28000179338242
constant: false
boundary condition: false
is: CHEBI:4167
has only substance units: false
is: SBO:0000247
type: Species
name: glucose
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260018#ca0256fc_efb3_4b12_9a73_d136f3930e05
value: 0.293
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#c6724ed2_7730_4fbd_9c22_866a060aa424
value: 2.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#dd8092e1_7087_4e87_99f7_24d494b71cb1
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_92b816c7_b147_4128_abed_2c8d5bfa58bf
reversible: false
name: UDP to UTP pseudoreaction
fast: false
modifier: MODEL1303260018#
type: Reaction
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1303260018#_5cc709b2_7219_4834_9819_12a312d32655
stoichiometry: 1.0
species: meta EtOH
type: SpeciesReference

meta ADH ADH5
name: alcohol dehydrogenase [ADH5]
is: SBO:0000176
is version of: http://identifiers.org/ec-code/1.1.1.1
type: Reaction
is: R00754
modifier: MODEL1303260018#
is version of: GO:0004022
reversible: true
fast: false

MODEL1303260018
species: meta F16bP
species: meta HXK1
name: min
name: phosphoglycerate kinase kinetics
reaction: meta ADH ADH1
species: meta CDC19
species: meta PGM2
species: meta ADP
name: reversible michaelis-menten: ordered uni-bi
reaction: meta AK
species: meta HOR2
reaction: meta PGI
species: meta T6P
species: meta F6P
species: meta F26bP
species: meta GPD1
species: meta TPI1
species: meta ACE
species: meta DHAP
name: irreversible mass action
species: meta AcAld
species: meta PYR
species: meta PDC1
species: meta PFK1
reaction: meta PYK CDC19
species: meta G1P
reaction: meta HXK HXK2
reaction: meta ATPase
name: phosphofructokinase kinetics with Keq
reaction: meta FBA
name: reversible michaelis-menten: one substrate, one product
reaction: meta HXK HXK1
reaction: meta PDC PDC1
species: meta PGM1
notes: Smallbone2013 - Glycolysis in S.cerevisiae - Iteration 18 This model is described in the article: A model of yeast glycolysis based on a consistent kinetic characterization of all its enzymes Kieran Smallbone, Hanan L. Messiha, Kathleen M. Carroll, Catherine L. Winder, Naglis Malys, Warwick B. Dunn, Ettore Murabito, Neil Swainston, Joseph O. Dada, Farid Khan, Pınar Pir, Evangelos Simeonidis, Irena Spasić, Jill Wishart, Dieter Weichart, Neil W. Hayes, Daniel Jameson, David S. Broomhead, Stephen G. Oliver, Simon J. Gaskell, John E.G. McCarthy, Norman W. Paton, Hans V. Westerhoff, Douglas B. Kell, Pedro Mendes FEBS Letters (in press) Abstract: We present an experimental and computational pipeline for the generation of kinetic models of metabolism, and demonstrate its application to glycolysis in Saccharomyces cerevisiae. Starting from an approximate mathematical model, we employ a “cycle of knowledge” strategy, identifying the steps with most control over flux. Kinetic parameters of the individual isoenzymes within these steps are measured experimentally under a standardised set of conditions. Experimental strategies are applied to establish a set of in vivo concentrations for isoenzymes and metabolites. The data are integrated into a mathematical model that is used to predict a new set of metabolite concentrations and reevaluate the control properties of the system. This bottom-up modelling study reveals that control over the metabolic network most directly involved in yeast glycolysis is more widely distributed than previously thought. This model is hosted on BioModels Database and identified by: MODEL1303260018 . To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models . To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more …
species: meta UDG
reaction: meta ENO ENO1
species: meta ATP
reaction: meta PGK
name: irreversible michaelis-menten: one substrate, no product
name: UGP kinetics
species: meta PYK2
reaction: meta acetate branch
species: meta GPM1
species: meta PGI1
species: meta TRH
species: meta GLY
reaction: meta TPP
reaction: meta ADH ADH5
curated: false
name: irreversible michaelis-menten: two substrates, no products
species: meta GLC
reaction: meta TDH TDH1
name: reversible michaelis-menten: two substrates, two products, three inhibitors, non-competitive inhibition
reaction: meta PDC PDC5
name: triose-phosphate isomerase kinetics
name: max
species: meta RHR2
compartment: meta cell
species: meta TDH3
species: meta GAP
species: meta NADH
name: HXK inhibition by T6P
species: meta TPS1
reaction: meta succinate branch
species: meta GLK1
species: meta NAD
name: facilitated diffusion: symmetrical carrier
species: meta PFK2
reaction: meta UGP
species: meta TPS2
species: meta PEP
reaction: meta HXT
species: meta AMP
species: meta TDH1
reaction: meta GPD
reaction: meta TDH TDH2
type: SBMLModel
species: meta UGP1
species: meta UDP

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constant: true
units: litre
value: 5.0E-15
name: volume
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260018#f8e84b60_cb8e_4527_b7b1_d231ab8fca78
stoichiometry: 1.0
species: meta GLY
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_3f600b41_22ae_44f1_b15c_a1242da191bf
value: 0.09
type: LocalParameter

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value: 0.11
type: LocalParameter

meta TDH2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: meta cell
name: TDH2
type: Species

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stoichiometry: 2.0
species: meta ADP
type: SpeciesReference

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stoichiometry: 1.0
species: meta F16bP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_8b594195_9d28_424c_8554_a6a446369144
value: 564.38
type: LocalParameter

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value: 1.0
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http://identifiers.org/biomodels.db/MODEL1303260018#f54cec2e_2e43_47a5_85ae_94b0eea2e602
value: 0.069
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_71d202a6_29c4_446b_8c23_2fdcc41f207c
value: 3.5
type: LocalParameter

meta SUC
has only substance units: false
is: CHEBI:30031
initial concentration: 0.0
name: succinate
is: SBO:0000247
type: Species
initial amount: NaN
is: C00042
constant: true
boundary condition: true
in compartment: meta cell

meta PGM
type: Reaction
fast: false
modifier: MODEL1303260018#
is: SBO:0000176
is version of: http://identifiers.org/ec-code/5.4.2.2
name: phosphoglucomutase
reversible: true

meta BPG
has only substance units: false
in compartment: meta cell
type: Species
constant: false
initial amount: NaN
boundary condition: false
initial concentration: 7.36873499865602E-4
is: CHEBI:16001
name: 1,3-bisphosphoglycerate
is: C00236
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1303260018#_6741bb18_4f01_49f2_9277_3899c0997db8
name: mM
type: SBMLUnitsDef

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constant: true
value: 1.39784619487425
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260018#e6f03b19_5ca7_44b0_8074_dc60b18c65cb
value: 3.0
type: LocalParameter

meta AK
is: SBO:0000176
fast: false
modifier: MODEL1303260018#
is: R00127
type: Reaction
is version of: GO:0004017
reversible: true
is version of: http://identifiers.org/ec-code/2.7.4.3
name: adenylate kinase

http://identifiers.org/biomodels.db/MODEL1303260018#_5db76eec_89ee_4853_85ac_70d778a3df47
stoichiometry: 1.0
species: meta T6P
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stoichiometry: 1.0
species: meta BPG
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stoichiometry: 1.0
species: meta ADP
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stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

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value: 0.3
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stoichiometry: 1.0
species: meta ADP
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stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#f763c8fd_fc33_406d_818d_a8494381d49b
value: 6.454
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_024f9667_ffd2_426a_ab5e_613da5e7f269
exponent: -1.0
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kind: SECOND
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260018#ee9b3178_927e_4b0f_99ab_21a59c3ae17f
value: 0.423
type: LocalParameter

meta TDH TDH3
is version of: GO:0004365
is: SBO:0000176
type: Reaction
modifier: MODEL1303260018#
name: glyceraldehyde phosphate dehydrogenase [TDH3]
is version of: http://identifiers.org/ec-code/1.2.1.12
is: R01061
fast: false
reversible: true

http://identifiers.org/biomodels.db/MODEL1303260018#_0d7bc43e_81ee_4008_bda4_17358eb63111
value: 0.11
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http://identifiers.org/biomodels.db/MODEL1303260018#_3668b874_b437_45d0_a078_4b38853a4da7
stoichiometry: 1.0
species: meta ADP
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meta PGK
reversible: true
type: Reaction
is: R01512
is version of: GO:0004618
fast: false
modifier: MODEL1303260018#
is: SBO:0000176
name: 3-phosphoglycerate kinase
is version of: http://identifiers.org/ec-code/2.7.2.3

http://identifiers.org/biomodels.db/MODEL1303260018#ebf8b619_ddc6_4099_a2e8_7cfa00e98aca
value: 0.06
type: LocalParameter

meta G6P
has only substance units: false
initial amount: NaN
boundary condition: false
is: SBO:0000247
is: C00668
constant: false
is: CHEBI:17665
name: glucose 6-phosphate
type: Species
in compartment: meta cell
initial concentration: 0.772483203645216

http://identifiers.org/biomodels.db/MODEL1303260018#_54832dd3_2ae2_4b0f_9c2d_9f32e86b0366
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_15d14a25_cb30_4d70_aede_6d62b7b8f691
units: dimensionless
value: 800.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_7b49026a_ee2c_4e47_8f4d_f80ed2271b8f
constant: false
value: NaN
name: glycerate phosphates
type: Parameter

meta TPI
is version of: GO:0004807
fast: false
modifier: MODEL1303260018#
is: SBO:0000176
is version of: http://identifiers.org/ec-code/5.3.1.1
is: R01015
reversible: true
type: Reaction
name: triosephosphate isomerase

http://identifiers.org/biomodels.db/MODEL1303260018#b8a0d157_84a2_4855_a4e5_892d0db00d89
stoichiometry: 1.0
species: meta GLCx
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_231b2f53_c150_44b3_bbf5_91def4d6532b
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

meta ADH ADH1
modifier: MODEL1303260018#
is version of: GO:0004022
reversible: true
is: R00754
is: SBO:0000176
is version of: http://identifiers.org/ec-code/1.1.1.1
name: alcohol dehydrogenase [ADH1]
type: Reaction
fast: false

meta UDG
type: Species
has only substance units: false
name: UDP glucose
is: SBO:0000247
in compartment: meta cell
constant: false
boundary condition: true
initial amount: NaN
initial concentration: 0.467246194874247
is: CHEBI:18066

http://identifiers.org/biomodels.db/MODEL1303260018#a7df413e_8bbc_4cf4_8333_93f9245493b4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_914866d6_e48e_489f_a511_29a57fb63005
value: 21.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#cbb7424a_fb7c_4d4c_b95f_92a1cbb30ce3
value: 17.0
type: LocalParameter

meta PYR
boundary condition: false
type: Species
initial concentration: 2.10847140717419
in compartment: meta cell
constant: false
name: pyruvate
initial amount: NaN
is: C00022
has only substance units: false
is: SBO:0000247
is: CHEBI:15361

http://identifiers.org/biomodels.db/MODEL1303260018#bc3e9551_615c_4acb_9a58_6a4a22465f0c
constant: false
units: dimensionless
value: NaN
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260018#_31365b93_d5a1_45db_9082_7d69e9844569
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

meta TRH
boundary condition: true
type: Species
is: SBO:0000247
initial amount: NaN
constant: true
in compartment: meta cell
has only substance units: false
initial concentration: 0.0153878853696526
name: trehalose
is: CHEBI:16551
is: C01083

http://identifiers.org/biomodels.db/MODEL1303260018#c38d6cc4_d791_41b6_b76e_3711c66c318f
value: 0.23
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_7e05980e_b3eb_43e5_b8c8_eac27bc2d7b7
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_1ad6ef75_d282_4d6e_9dea_d53333f8b905
value: 0.06
type: LocalParameter

meta CDC19
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 2.0483901071712
initial amount: NaN
in compartment: meta cell
name: CDC19
type: Species

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stoichiometry: 1.0
species: meta G3P
type: SpeciesReference

meta acetate branch
is: SBO:0000176
type: Reaction
fast: false
name: acetate branch
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reversible: false
is version of: GO:0006105

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stoichiometry: 1.0
species: meta P2G
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stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_802ea487_f9bf_454d_a285_71f2846b5088
value: 0.281
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#d8e5f3f6_bf0b_4f37_9d1a_005d96fc6078
value: 0.4622
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#f60172b3_e49c_4759_adb9_e366feaceaf4
value: 0.2
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value: 0.11
type: LocalParameter

meta HOR2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0054734695639756
initial amount: NaN
in compartment: meta cell
name: HOR2
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stoichiometry: 1.0
species: meta NADH
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value: 18.162
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value: 30.0
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value: 10.0
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http://identifiers.org/biomodels.db/MODEL1303260018#_4c15f00b_f1a4_4927_9eeb_3e49cf3a1270
units: dimensionless
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meta T6P
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meta GPM
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meta ADH5
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is: CHEBI:16236
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meta PFK
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value: 3.8
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_4a83f3ad_a37d_4405_8de1_b3c9afcc4840
value: 5.25
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#e8cb99d3_70af_41fb_bc60_8066e06cc989
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260018#e25033d6_1103_4451_86c4_273766a99848
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#f5bc1676_8feb_4e61_b72d_e37981305134
value: 0.0035
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_8d9c0d8a_7157_4b27_8645_67b1832dea05
value: 8.633
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_5b273ada_edb9_449a_ae2e_eae156da42f0
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

meta PYK PYK2
reversible: true
name: pyruvate kinase [PYK2]
is: R00200
is version of: http://identifiers.org/ec-code/2.7.1.40
is: SBO:0000176
type: Reaction
modifier: MODEL1303260018#
is version of: GO:0004743
fast: false

http://identifiers.org/biomodels.db/MODEL1303260018#_308d9092_1851_40bf_823d_76f53e33de4f
value: 0.031
type: LocalParameter

meta TPS
is: SBO:0000176
fast: false
modifier: MODEL1303260018#
type: Reaction
is version of: http://identifiers.org/ec-code/2.4.1.15
name: T6P synthase
reversible: false

http://identifiers.org/biomodels.db/MODEL1303260018#_3a4dc0b8_eb57_4a8b_ba63_f1d23dcd64a1
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_5ed9505b_e862_47a6_a762_86240838c012
value: 19.87
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_505b9acb_c0af_4181_ab17_09a7ffa75169
constant: true
units: dimensionless
value: 14492.7536231884
type: Parameter

meta TDH1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.350864642801396
initial amount: NaN
in compartment: meta cell
name: TDH1
type: Species

meta NADH
initial amount: NaN
constant: false
name: NADH
initial concentration: 0.0867096979846952
has only substance units: false
is: SBO:0000247
boundary condition: true
is: CHEBI:16908
type: Species
is: C00004
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260018#_759c677a_f215_4863_ac81_bffad2826806
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_0b74adc5_9795_4cd3_a038_07d360ea8ae1
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260018#a13f1e84_bc78_471d_9d72_f7d832d9b596
value: 58.6
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_9567c9b9_b895_47d5_ab19_15098982a1a8
value: 9.3
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_60d74ba2_5296_4de2_a8e3_a2ce2affe61a
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#af4deee3_ad41_4c85_93e2_024a2e44f239
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_95fcc190_0c52_473f_83a6_10307cb8f330
value: 0.4507
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_58712e2e_16d7_4647_8ff7_3243d56ecc10
value: 0.32
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#ba8ad9cc_5759_4c9d_9d54_8348d1ec8c23
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_0eaa2d70_9c54_4919_aea5_8ca508180d07
value: 9.3
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_0759eb1b_4260_40de_b417_798fcc54d64a
value: 0.06
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_2c816390_2ac4_435a_b21c_aa104d5810c5
value: 0.54
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#dcc88aad_046c_42f2_9b96_eb421ad88efd
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_86f8f263_3b36_4d6d_96ca_e3836587355c
value: 0.71
type: LocalParameter

meta RHR2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0511804773718313
initial amount: NaN
in compartment: meta cell
name: RHR2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#e38420b1_d8f4_4c79_a32c_61636af78587
value: 0.043
type: LocalParameter

meta ADH1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.163908510928009
initial amount: NaN
in compartment: meta cell
name: ADH1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260018#f0d24fef_5b2a_4eab_a309_c5893516b4fc
value: 0.0098
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_0e4a3241_033e_458b_a5ac_6bed1fcffa12
value: 0.886
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#d5ed866a_dbb1_4ac8_97a2_5970d751e2d5
name: mM per second
type: SBMLUnitsDef

meta GPP
is: SBO:0000176
type: Reaction
modifier: MODEL1303260018#
is: R00841
reversible: false
is: http://identifiers.org/ec-code/3.1.3.21
name: glycerol 3-phosphatase
fast: false

http://identifiers.org/biomodels.db/MODEL1303260018#_0e90f61d_6d37_47fd_a306_548b2264627c
value: 0.17
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#c478a4be_fffe_4cfb_b6be_4d6f68bdf2f8
name: mmol
type: SBMLUnitsDef

meta TPP
is: SBO:0000176
type: Reaction
modifier: MODEL1303260018#
reversible: false
is version of: http://identifiers.org/ec-code/3.1.3.12
fast: false
name: T6P phosphatase

http://identifiers.org/biomodels.db/MODEL1303260018#_4edec72a_519a_4fca_bed5_4bc8c9bc3a8e
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_83240557_3bef_478b_b589_4956f91a8d3b
stoichiometry: 1.0
species: meta F16bP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_33ec2990_9e34_428d_b3c3_c728cf35f047
value: 0.104
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_3a6c1e1c_53c2_43cd_a6bf_9077e1877f61
stoichiometry: 1.0
species: meta T6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#_333b32df_b5c8_470a_94b3_a8ccb96d6300
stoichiometry: 1.0
species: meta P3G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260018#acffe77c_c19b_436f_a278_27f6d0d8ea17
value: 6.16
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260018#_758962f9_9183_4b5b_8225_db74e72f15c1
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260018#d0404f11_2304_4986_8472_89090aa2de4b
value: 1.5
type: LocalParameter

meta AcAld
type: Species
is: CHEBI:15343
is: C00084
initial amount: NaN
has only substance units: false
constant: false
in compartment: meta cell
boundary condition: false
initial concentration: 0.178140579850657
name: acetaldehyde
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1303260018#aab8be04_2133_4700_a62e_a0132be4bb22
value: 19.12
type: LocalParameter

ORG:
  orgname: University of Manchester
n:
  given: Kieran
  family: Smallbone

W3 CDTF: Wed Nov 14 14:48:54 GMT 2012