http://identifiers.org/biomodels.db/MODEL1303260017#_16b4489e_46e4_4b19_a21a_380d97d9d6bc
value: 0.0745258294103764
type: LocalParameter

meta TDH2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: meta cell
name: TDH2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#_2a12d2f9_150c_45b1_9494_bf468da022db
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_5da83b00_576c_4e5b_8b22_91afaf94a3cc
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_358a98fa_bc09_43b7_8615_4d63d713d0b3
constant: false
value: NaN
name: glycerate phosphates
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260017#c84332d4_4005_42fa_9f94_93fa14ab3721
stoichiometry: 3.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#b0440b3b_2488_4639_ab4d_8dba1044b680
value: 0.104
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_893d1bfa_ea57_4a27_8dad_08c95dd9ea17
stoichiometry: 1.0
species: meta UTP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#ea8d1754_0cdb_4ca0_b985_f715a05baa3f
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_0efbc161_f025_4f4d_9501_6210a1e83cce
value: 3.8
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_59418566_61c2_4c73_a0b5_22184b8f5a4c
value: 3.35
type: LocalParameter

W3 CDTF: Wed Nov 14 14:35:00 GMT 2012

http://identifiers.org/biomodels.db/MODEL1303260017#_97665d77_30b7_4798_a29c_971dee5fcef4
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#ee9eb1c6_f8aa_44ed_ace8_1b235d9bc121
value: 30.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_87c2fef1_7f23_4957_aed1_32d21c7464a2
stoichiometry: 1.0
species: meta GLCx
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#eba8e934_e48e_4ffb_99ef_2a97b96b79f2
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta TDH1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.087716160700349
initial amount: NaN
in compartment: meta cell
name: TDH1
type: Species

meta HXK HXK1
is version of: http://identifiers.org/ec-code/2.7.1.1
name: hexokinase [HXK1]
is: SBO:0000176
is: R02848
fast: false
modifier: MODEL1303260017#
type: Reaction
reversible: true
is version of: GO:0004396

meta GPD2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.98351416606057E-4
initial amount: NaN
in compartment: meta cell
name: GPD2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#_980524c3_8eca_40e0_ac4d_81bc2c965678
value: 0.92
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#a5abadf9_4756_4dc4_a36b_fa5317db22ce
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#a6810bb2_62d0_4cdb_9326_0e30a59a3a39
value: 0.23
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#c2e9e417_03aa_46ad_a88d_51514da39742
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_80b10d75_1840_4ff8_a57f_b71c6879542e
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

meta PGI
is: SBO:0000176
reversible: true
is: R00771
name: phosphoglucose isomerase
type: Reaction
is version of: http://identifiers.org/ec-code/5.3.1.9
is version of: GO:0004347
modifier: MODEL1303260017#
fast: false

http://identifiers.org/biomodels.db/MODEL1303260017#ebdc879c_636d_4d27_ad78_186f748de836
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_480cf727_b871_4652_ad57_ecbf86513e44
value: 0.17
type: LocalParameter

W3 CDTF: Sun Nov 09 00:00:00 GMT 2008

http://identifiers.org/biomodels.db/MODEL1303260017#eb6279bb_0286_42d3_a7b8_17a30fd07206
units: dimensionless
value: 0.1667
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_0535c23d_c4b2_4b51_b718_b2975cf64caf
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_1fe44d67_5e95_448b_bfc4_7f83157f3dcd
value: 0.75
type: LocalParameter

meta HXK HXK2
is: R02848
modifier: MODEL1303260017#
type: Reaction
reversible: true
name: hexokinase [HXK2]
fast: false
is: SBO:0000176
is version of: GO:0004396
is version of: http://identifiers.org/ec-code/2.7.1.1

http://identifiers.org/biomodels.db/MODEL1303260017#_10aec94e_52e6_4280_bbc8_19545037e6e6
stoichiometry: 1.0
species: meta P3G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_4ca1a626_5b1f_418f_8315_3400fba310da
value: 0.0098
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_7544cc8a_35f9_4871_a89a_836ae999a353
stoichiometry: 1.0
species: meta UDG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_4caebf2f_36b2_47ff_b400_af9c3cfff86f
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260017#_2e83fead_e5ce_4848_92a0_bfbcf647d74a
value: 6.454
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_50368b77_faa9_442d_84da_898ee5486d49
value: 30.0
type: LocalParameter

meta G6P
initial amount: NaN
is: CHEBI:17665
constant: false
name: glucose 6-phosphate
has only substance units: false
type: Species
is: C00668
is: SBO:0000247
initial concentration: 0.193120800911304
in compartment: meta cell
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1303260017#a09c1add_30ec_45cb_b068_d20f455990f9
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta TDH3
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.05110118662137
initial amount: NaN
in compartment: meta cell
name: TDH3
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#a5f3e4c8_c573_443d_8527_40ea2b715266
value: 1.2
type: LocalParameter

meta TPP
fast: false
name: T6P phosphatase
modifier: MODEL1303260017#
is version of: http://identifiers.org/ec-code/3.1.3.12
is: SBO:0000176
reversible: false
type: Reaction

http://identifiers.org/biomodels.db/MODEL1303260017#b3f43e9a_6bab_42c6_9221_a2550e7756a2
name: mM per second
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260017#_9f901ef1_de94_4505_99f4_81b7cb465aaa
constant: true
units: litre
value: 2.0E-14
name: volume
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260017#_1b9eb7c2_b490_4d4d_a6c5_45907073a350
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_78689b05_2c70_4e48_95a4_d5f059ad3c1f
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#ac61d126_07f6_4621_b903_53484efaadda
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#a671cd73_d4b7_47c3_a978_281a119a160f
value: 20.146
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#ec72c579_a966_4e11_83d5_b4fd4432a602
value: 2.92
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_955693c3_bd01_44eb_82d3_977b75500a28
value: 1.2
type: LocalParameter

meta PGK
type: Reaction
fast: false
is version of: http://identifiers.org/ec-code/2.7.2.3
reversible: true
is version of: GO:0004618
is: R01512
is: SBO:0000176
modifier: MODEL1303260017#
name: 3-phosphoglycerate kinase

http://identifiers.org/biomodels.db/MODEL1303260017#_1995a5f3_eed1_4438_8efc_bc41afd4078d
stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#a7852972_3d31_4768_b396_ad54aab50b54
units: dimensionless
value: 100.0
type: LocalParameter

meta FBA1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.334598664262206
initial amount: NaN
in compartment: meta cell
name: FBA1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#d9a5e5cd_4742_4a38_9209_172186e9573d
value: 0.11
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_531cda48_5825_47e0_9b57_de3a118cd6b8
value: 0.04
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#f3263cfb_1b22_4e87_a4e9_be1426f22b5d
value: 0.06
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_284c408f_481e_4585_b36b_ccd1771debcd
value: 10.32
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_41a8b528_7455_48b9_8995_4a0b1dc0dc81
value: 0.495
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_1a714a38_3c4f_4db6_a930_c6e217cc4060
value: 7.6
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#bbb2f746_7617_4f93_8090_914c2274ad98
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

meta PYK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00151748381804475
initial amount: NaN
in compartment: meta cell
name: PYK2
type: Species

meta TDH TDH1
fast: false
is version of: GO:0004365
reversible: true
name: glyceraldehyde phosphate dehydrogenase [TDH1]
is version of: http://identifiers.org/ec-code/1.2.1.12
is: R01061
type: Reaction
is: SBO:0000176
modifier: MODEL1303260017#

meta FBA
modifier: MODEL1303260017#
is: SBO:0000176
fast: false
name: fructosebisphosphate aldolase
type: Reaction
is version of: http://identifiers.org/ec-code/4.1.2.13
is: R01068
is version of: GO:0004332
reversible: true

meta UDP
has only substance units: false
in compartment: meta cell
type: Species
initial amount: NaN
name: UDP
initial concentration: 0.2815
is: CHEBI:17659
is: SBO:0000247
boundary condition: false
constant: false

http://identifiers.org/biomodels.db/MODEL1303260017#f7509632_b4f8_48cb_8fb8_0288cb72164a
value: 1.1
type: LocalParameter

meta GPP
is: http://identifiers.org/ec-code/3.1.3.21
fast: false
modifier: MODEL1303260017#
is: SBO:0000176
type: Reaction
is: R00841
name: glycerol 3-phosphatase
reversible: false

http://identifiers.org/biomodels.db/MODEL1303260017#_5feb715b_d2e2_47dd_9b13_515655908fca
value: 4.8
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_5c3c8311_4a28_4388_abe5_77445a04e292
value: 0.243
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_7c93e7ba_c3a1_4105_a8fa_a596839e075c
units: dimensionless
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_94784be7_fe34_4554_a8f2_51d0183930b3
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260017#d9e77dc7_3e2a_4fcd_80cb_35f3aa921027
stoichiometry: 1.0
species: meta F16bP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#a08286a7_69ac_43fd_ab36_168f19131f22
units: dimensionless
value: 3.0
type: LocalParameter

meta RHR2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0127951193429578
initial amount: NaN
in compartment: meta cell
name: RHR2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#_2713f268_d471_4856_9e34_ad00fddb007f
units: dimensionless
value: 0.91
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#ef540df5_bd42_4e66_85f2_3cd55184c761
constant: false
units: dimensionless
value: NaN
type: Parameter

meta GPD1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00170877794272468
initial amount: NaN
in compartment: meta cell
name: GPD1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#_45d6f4aa_0381_4686_965a_7309f1d7e305
value: 3.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#cbfbe6b2_9b2e_4de3_8f3c_7d42be2f9cee
exponent: -1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260017#aa27e482_7328_4892_8933_8f1fc56ffd82
value: 0.92
type: LocalParameter

meta GPM
reversible: true
fast: false
is version of: GO:0004619
is version of: http://identifiers.org/ec-code/5.4.2.1
name: phosphoglyceromutase
modifier: MODEL1303260017#
is: SBO:0000176
type: Reaction
is: R01518

http://identifiers.org/biomodels.db/MODEL1303260017#_88cc15b0_66d8_4064_b54c_901189e8aee7
units: dimensionless
value: 0.045
type: LocalParameter

meta CDC19
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.512097526792801
initial amount: NaN
in compartment: meta cell
name: CDC19
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#_20e4e866_425b_4aef_b289_2a6fc32a6bc7
value: 0.069
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_2e9ddb33_a8a2_4f44_98f7_03128b798260
constant: true
units: dimensionless
value: 14492.7536231884
type: Parameter

meta ATPase
reversible: false
name: ATPase
fast: false
is: SBO:0000176
is version of: GO:0016887
type: Reaction
modifier: MODEL1303260017#

meta succinate branch
reversible: false
is version of: GO:0006105
name: succinate branch
is: SBO:0000176
fast: false
type: Reaction
modifier: MODEL1303260017#

http://identifiers.org/biomodels.db/MODEL1303260017#f01d8bc6_367f_433f_8b5b_c8078cdf313f
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

meta ADH5
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00106249605621922
initial amount: NaN
in compartment: meta cell
name: ADH5
type: Species

meta GPM1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.182500074724267
initial amount: NaN
in compartment: meta cell
name: GPM1
type: Species

meta SUC
is: SBO:0000247
is: CHEBI:30031
initial amount: NaN
initial concentration: 0.0
has only substance units: false
in compartment: meta cell
name: succinate
boundary condition: true
is: C00042
constant: true
type: Species

meta ENO ENO1
reversible: true
is version of: http://identifiers.org/ec-code/4.2.1.11
fast: false
type: Reaction
modifier: MODEL1303260017#
is: R00658
name: enolase [ENO1]
is: SBO:0000176
is version of: GO:0004634

http://identifiers.org/biomodels.db/MODEL1303260017#_4ed3c0b1_c798_4a04_9ebb_b06ada5d8746
stoichiometry: 1.0
species: meta G1P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#b59ed74f_0842_4da1_9480_628698166ef0
value: 2.33999999999999
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_9fa6fb63_c27b_48a5_a50e_9314f2ec9e23
stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_5b33d459_728b_47e7_8d1c_01a493bfbcc0
value: 17.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#e51885f8_acaf_43bc_993e_bca53d6037b8
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_4144b313_0c34_41a8_9715_9667aa012b3a
value: 2.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#f4e51542_6ca4_4707_9fa0_341e3c7e3f1b
value: 0.73
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#f14a22ab_f9c0_4116_b8ae_70aaaedd8f3d
constant: true
units: dimensionless
value: 6.7
type: Parameter

meta ATP
boundary condition: false
name: ATP
initial amount: NaN
is: SBO:0000247
constant: false
is: CHEBI:15422
in compartment: meta cell
has only substance units: false
type: Species
is: C00002
initial concentration: 4.29

http://identifiers.org/biomodels.db/MODEL1303260017#_925791f3_3719_4974_8140_a16639b5ee87
value: 0.281
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#d55feb9a_db8d_4536_86aa_068feadbc5c7
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_50e92f80_27ef_4ed3_a30b_b0a4c8799f5f
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

meta ENO ENO2
modifier: MODEL1303260017#
type: Reaction
is version of: GO:0004634
is: R00658
is: SBO:0000176
is version of: http://identifiers.org/ec-code/4.2.1.11
fast: false
name: enolase [ENO2]
reversible: true

http://identifiers.org/biomodels.db/MODEL1303260017#_352379f9_aa95_4eeb_b48e_4d01587c643d
value: 0.09
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#e5fe2f17_86b5_498b_969f_2e39b44705dd
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_38c30a44_bcd5_40c1_83f9_569ec47e2766
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_95dec308_4740_4219_bb97_478ec04a9fe5
value: 0.0035
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#fca82b2f_a824_4e47_bbbf_eb18ceed61f5
stoichiometry: 1.0
species: meta T6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_44cd132b_db81_4efc_b901_c6f4adb12e3b
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_3dc61e9a_dcab_4c6f_a8dd_8f27fd331a0c
units: dimensionless
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_9644d3f6_cde3_49f2_964c_32557f665541
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_04ab9ea2_e6e7_4004_b9c4_ab226fc70382
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260017#_88697bfc_3044_40c1_a0f3_99677c088a32
value: 0.195
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#c1ec32be_3242_4c3c_9e68_204ef7516d99
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#cb530c86_9fd3_43cf_a957_928ee2b2e8f5
value: 0.031
type: LocalParameter

meta TPI1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.073589454911377
initial amount: NaN
in compartment: meta cell
name: TPI1
type: Species

meta ADH1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0409771277320022
initial amount: NaN
in compartment: meta cell
name: ADH1
type: Species

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value: 5.25
type: LocalParameter

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exponent: -1.0
scale: -3
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kind: MOLE
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value: 0.043
type: LocalParameter

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value: 0.77
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_99937880_c5eb_475c_b73e_31aec0b4c229
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type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_73cd043c_bc5b_4fe7_9283_c9d2d5a28d51
value: 0.11
type: LocalParameter

meta GLK1
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constant: true
boundary condition: true
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initial concentration: 0.0112717406104807
initial amount: NaN
in compartment: meta cell
name: GLK1
type: Species

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units: dimensionless
value: 5.12
type: LocalParameter

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species: meta NADH
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value: 9.3
type: LocalParameter

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initial amount: NaN
in compartment: meta cell
name: HOR2
type: Species

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is: SBO:0000176
fast: false
type: Reaction
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name: T6P synthase

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value: 18.162
type: LocalParameter

meta PGM
modifier: MODEL1303260017#
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fast: false
reversible: true
is version of: http://identifiers.org/ec-code/5.4.2.2
is: SBO:0000176

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value: 0.65
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species: meta PYR
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stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

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value: 0.0
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value: 0.0995
type: LocalParameter

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value: 0.5
type: LocalParameter

meta UTP
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initial amount: NaN
constant: false
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is: SBO:0000247
initial concentration: 0.6491
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type: Species
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boundary condition: false

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constant: false
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is: CHEBI:15343
is: SBO:0000247

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stoichiometry: 1.0
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type: SpeciesReference

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value: 0.06
type: LocalParameter

meta GPD
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reversible: true
modifier: MODEL1303260017#
fast: false
type: Reaction
is: R00842
is: http://identifiers.org/ec-code/1.1.1.94
is: SBO:0000176

meta GAP
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type: Species
has only substance units: false
initial concentration: 0.0789727571926259
is: CHEBI:29052
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boundary condition: false
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constant: false
name: glyceraldehyde 3-phosphate

meta TPS2
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type: Species
is: SBO:0000252
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boundary condition: true
is: P31688
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has only substance units: false

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constant: true
units: dimensionless
value: 6500.0
type: Parameter

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stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_697aa61f_17de_471b_9661_b0170451807c
units: dimensionless
value: 0.19
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_81aa1faf_11af_44dd_aa50_525427e45d40
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type: LocalParameter

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stoichiometry: 1.0
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meta HXT
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modifier: MODEL1303260017#
type: Reaction
fast: false
name: glucose transport

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stoichiometry: 1.0
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units: dimensionless
value: 800.0
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meta acetate branch
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reversible: false
name: acetate branch
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meta PFK
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fast: false
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is version of: GO:0003872
is: R00756
type: Reaction
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value: 8.5
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http://identifiers.org/biomodels.db/MODEL1303260017#_8ac197f6_f55e_43f0_a8b7_e34eb81da69f
value: 58.6
type: LocalParameter

meta UGP
reversible: false
is version of: http://identifiers.org/ec-code/2.7.7.9
fast: false
modifier: MODEL1303260017#
type: Reaction
name: UDP glucose phosphorylase
is: SBO:0000176

meta TPS1
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is: Q00764
has only substance units: false
in compartment: meta cell
name: TPS1
is encoded by: S000000330
initial amount: NaN
type: Species
is: SBO:0000252
constant: true
initial concentration: 8.48120435592663E-4

http://identifiers.org/biomodels.db/MODEL1303260017#_054873bd_86fb_4bc7_a2ea_44afa58fda19
constant: true
units: dimensionless
value: 0.00533412710224736
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260017#_361c3c41_14d3_4adb_aa79_0cc48313931b
value: 30.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#ef1bb7b3_8cd1_472f_92fa_3595c4c52598
value: 1.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_81010c05_7d0b_48ad_88bf_9a687788c213
stoichiometry: 1.0
species: meta ATP
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http://identifiers.org/biomodels.db/MODEL1303260017#_5d38ac9e_b8b5_43e8_b0f8_e69c74fe9788
value: 1.11
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_2cb3d20c_3f99_489d_9d93_bf05a0df8cbd
value: 0.23
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#d9c40db1_efb3_4344_b5b7_b5a989b77f33
value: 1.41
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_2fe15c80_275e_4993_a3e4_df76b0788017
units: dimensionless
value: 10000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_2285c349_0829_45ee_ad25_8accca556939
value: 4.139
type: LocalParameter

meta F26bP
name: fructose 2,6-bisphosphate
type: Species
in compartment: meta cell
constant: true
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initial amount: NaN
is: C00665
boundary condition: true
is: SBO:0000247
is: CHEBI:28602
initial concentration: 0.003

http://identifiers.org/biomodels.db/MODEL1303260017#_629d3056_edd9_455a_abdd_42e90575169c
stoichiometry: 1.0
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type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_0f336ede_3add_41b3_9cec_8caf5c5f848e
units: dimensionless
value: 0.66
type: LocalParameter

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stoichiometry: 1.0
species: meta NAD
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http://identifiers.org/biomodels.db/MODEL1303260017#_2d147b5c_33cb_4c88_807b_79d122ceaffd
value: 0.5
type: LocalParameter

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type: SpeciesReference

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type: SpeciesReference

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value: 0.0106
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_05eb1ba3_4667_41da_868b_79c7daa97ca5
value: 209.6
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_119e0dc3_8803_42bd_91d7_943362af51ba
value: 1.13333333333333
type: LocalParameter

meta DHAP
constant: false
boundary condition: false
name: dihydroxyacetone phosphate
has only substance units: false
initial concentration: 0.290344213186674
in compartment: meta cell
is: C00111
type: Species
is: SBO:0000247
is: CHEBI:16108
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260017#e1768395_ca93_4172_a173_2c0a4c12c374
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

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value: 0.54
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_5d9970ca_8287_4b8c_98f4_9f4c28ea927f
value: 0.23
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_9aa51b05_ccdd_4306_a3f3_3199b4e5f53d
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260017#f9396aaa_2a8b_4a0f_87b7_e97bc83963de
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

meta G3P
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in compartment: meta cell
has only substance units: false
name: glycerol 3-phosphate
is: CHEBI:15978
is: C00093
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is: SBO:0000247
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meta PDC5
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constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00308868608169189
initial amount: NaN
in compartment: meta cell
name: PDC5
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http://identifiers.org/biomodels.db/MODEL1303260017#_7e9ded4b_5c73_41bc_bd6b_bf6959ee4753
constant: false
units: dimensionless
value: NaN
type: Parameter

meta G1P
name: glucose 1-phosphate
is: CHEBI:16077
initial concentration: 0.13481212658623
boundary condition: false
constant: false
type: Species
has only substance units: false
initial amount: NaN
in compartment: meta cell
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1303260017#_8fc245c5_8834_4350_85f3_1a00c114e2ad
stoichiometry: 1.0
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http://identifiers.org/biomodels.db/MODEL1303260017#_72651850_0a4e_49a3_9ed9_56757c40233d
name: mmol
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260017#c2081695_21d7_4f1d_ae9f_f52252e7e246
value: 0.06
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_98e553df_48d9_48c1_900b_ccb2fbb3a3e9
stoichiometry: 1.0
species: meta PYR
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meta GLCx
in compartment: meta extracellular
type: Species
constant: true
initial concentration: 74.0
is: SBO:0000247
boundary condition: true
has only substance units: false
is: C00031
is: CHEBI:4167
initial amount: NaN
name: glucose

http://identifiers.org/biomodels.db/MODEL1303260017#_5264b998_e121_49fd_9cc5_f9530d3cf2a5
value: 0.883333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_1bea87fb_ca9e_4805_ad71_912592e0e902
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_367b32e4_2449_486e_ad6b_4906504ff62b
constant: true
units: dimensionless
value: 2000.0
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260017#_184cbc2c_bde4_474a_b714_d20513137245
units: dimensionless
value: 0.0845
type: LocalParameter

meta NAD
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initial amount: NaN
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name: NAD
in compartment: meta cell
is: SBO:0000247
initial concentration: 1.50329030201531
is: CHEBI:15846
has only substance units: false
is: C00003
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#c9fe4c89_d290_4b48_b9e9_203c07c7d1ab
value: 0.886
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#dfee8f56_fa23_4634_9a24_b0aeb15238f5
name: mM
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260017#_8c944013_78cc_4c20_bc2c_f55a5e5e824c
stoichiometry: 0.75
species: meta SUC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#fdeda68d_a9a9_48a6_aad4_6768f1917e6c
value: 0.2
type: LocalParameter

MODEL1303260017
species: meta GLCx
reaction: meta GPD
name: facilitated diffusion: symmetrical carrier
species: meta HOR2
curated: false
name: irreversible mass action
notes: Smallbone2013 - Glycolysis in S.cerevisiae - Iteration 17 This model is described in the article: A model of yeast glycolysis based on a consistent kinetic characterization of all its enzymes Kieran Smallbone, Hanan L. Messiha, Kathleen M. Carroll, Catherine L. Winder, Naglis Malys, Warwick B. Dunn, Ettore Murabito, Neil Swainston, Joseph O. Dada, Farid Khan, Pınar Pir, Evangelos Simeonidis, Irena Spasić, Jill Wishart, Dieter Weichart, Neil W. Hayes, Daniel Jameson, David S. Broomhead, Stephen G. Oliver, Simon J. Gaskell, John E.G. McCarthy, Norman W. Paton, Hans V. Westerhoff, Douglas B. Kell, Pedro Mendes FEBS Letters (in press) Abstract: We present an experimental and computational pipeline for the generation of kinetic models of metabolism, and demonstrate its application to glycolysis in Saccharomyces cerevisiae. Starting from an approximate mathematical model, we employ a “cycle of knowledge” strategy, identifying the steps with most control over flux. Kinetic parameters of the individual isoenzymes within these steps are measured experimentally under a standardised set of conditions. Experimental strategies are applied to establish a set of in vivo concentrations for isoenzymes and metabolites. The data are integrated into a mathematical model that is used to predict a new set of metabolite concentrations and reevaluate the control properties of the system. This bottom-up modelling study reveals that control over the metabolic network most directly involved in yeast glycolysis is more widely distributed than previously thought. This model is hosted on BioModels Database and identified by: MODEL1303260017 . To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models . To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more …
species: meta F6P
reaction: meta HXK GLK1
species: meta GLC
reaction: meta PDC PDC1
species: meta AcAld
reaction: meta PFK
species: meta DHAP
species: meta ADP
name: reversible michaelis-menten: one substrate, one product
species: meta NADH
reaction: meta PGM
name: reversible michaelis-menten: ordered uni-bi
species: meta SUC
reaction: meta TPS
name: reversible michaelis-menten: two noncompeting couples
name: reversible michaelis-menten: ordered bi-bi
species: meta HXK2
reaction: meta ATPase
species: meta ADH5
species: meta NAD
name: irreversible michaelis-menten: one substrate, no product
reaction: meta GPP
name: UGP kinetics
species: meta UDG
species: meta P2G
name: pyruvate kinase kinetics with F16bP activation
reaction: meta TPI
species: meta TPS1
species: meta G1P
name: irreversible michaelis-menten: two substrates, no products
species: meta GPM1
species: meta HXK1
species: meta GLY
species: meta T6P
name: min
name: phosphoglycerate kinase kinetics
initial assignment: MODEL1303260017#
species: meta PDC6
species: meta ATP
species: meta PDC1
reaction: meta ENO ENO2
reaction: meta PDC PDC6
name: reversible mass action
species: meta TRH
species: meta PDC5
reaction: meta ADH ADH1
is: http://identifiers.org/taxonomy/4932
reaction: meta PYK CDC19
name: reversible michaelis-menten: two substrates, two products, three inhibitors, non-competitive inhibition
species: meta F26bP
species: meta PFK2
reaction: meta AK
name: phosphofructokinase kinetics with Keq
reaction: meta acetate branch
species: meta GAP
type: SBMLModel
species: meta PGM1
species: meta EtOH
name: HXK inhibition by T6P
species: meta PGI1
reaction: meta PGI
compartment: meta cell
species: meta PYK2
area units: area
reaction: meta PYK PYK2
species: meta UGP1
reaction: meta GPM
species: meta ENO1
length unit: length
reaction: meta ENO ENO1
species: meta ACE
species: meta TDH1
species: meta PEP

meta AMP
constant: false
is: SBO:0000247
name: AMP
initial amount: NaN
has only substance units: false
initial concentration: 0.44
type: Species
is: C00020
in compartment: meta cell
is: CHEBI:16027
boundary condition: true

meta PGM2
constant: true
boundary condition: true
has only substance units: false
initial amount: NaN
type: Species
in compartment: meta cell
name: PGM2
is: P37012
is: SBO:0000252
is encoded by: S000004711
initial concentration: 3.1467219294138E-4

http://identifiers.org/biomodels.db/MODEL1303260017#_29889e7e_2216_41fe_ac18_ca606a77821b
units: dimensionless
value: 0.45
type: LocalParameter

meta PDC6
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constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0016352160527653
initial amount: NaN
in compartment: meta cell
name: PDC6
type: Species

meta BPG
boundary condition: false
is: CHEBI:16001
initial amount: NaN
initial concentration: 7.36873499865602E-4
type: Species
is: C00236
has only substance units: false
in compartment: meta cell
constant: false
is: SBO:0000247
name: 1,3-bisphosphoglycerate

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stoichiometry: 1.0
species: meta UTP
type: SpeciesReference

meta F16bP
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is: CHEBI:28013
name: fructose 1,6-bisphosphate
is: C05378
is: SBO:0000247
in compartment: meta cell
boundary condition: false
type: Species
initial concentration: 1.14580464751733
has only substance units: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260017#edfc0bf5_fad1_4ac3_8df3_b1f58c51966e
value: 0.49356
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_52bf0d46_160f_4549_a4c0_703365d7b193
value: 0.0
type: LocalParameter

meta T6P
name: trehalose 6-phosphate
initial amount: NaN
has only substance units: false
initial concentration: 0.02
constant: false
is: CHEBI:18283
boundary condition: false
is: SBO:0000247
type: Species
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260017#_22472d39_f802_4b3b_97a5_2d38feaf33d6
stoichiometry: 1.0
species: meta T6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_1a9e8a26_962d_4e7b_a38b_db903baa66f2
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_5707533e_7694_4a9e_8df6_70b5309d847f
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_866d96fd_9588_4c73_9c14_3762f178779c
value: 0.32
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#ee1bf0db_3f9a_4fca_a04c_be9da75c48ce
value: 8.633
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_5440f23f_21fd_4e3f_aa66_819ae8daa9f4
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_52a3caf9_4fa5_47ee_952c_070d5e15aebb
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

meta PDC PDC1
is version of: http://identifiers.org/ec-code/4.1.1.1
reversible: false
is: SBO:0000176
is version of: GO:0004737
is: R00636
fast: false
modifier: MODEL1303260017#
name: pyruvate decarboxylase [PDC1]
type: Reaction

http://identifiers.org/biomodels.db/MODEL1303260017#_34cffbb1_5654_47e8_8f51_95eff7c1874d
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_5c8e1335_653b_4522_a4f4_2f1725e304c5
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_1a51f12a_eaff_4001_a027_7d788f3752e2
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

meta extracellular
is: GO:0005576
constant: true
size: 1.0
spatial dimensions: 3.0
name: extracellular
type: Compartment

http://identifiers.org/biomodels.db/MODEL1303260017#c56264ae_06b6_4bcd_a008_65d7e67f5a28
value: 1.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#ea36fcf2_a80d_4dc6_83e7_db3d2e014cbd
stoichiometry: 1.0
species: meta UDG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#fdf7f6af_9c0e_4104_a45b_ecf910d85eaa
constant: true
value: 6.022140000000001E20
name: Avogadro constant
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260017#_93d1d77e_489b_41f4_b3dd_7aaeb3cb1722
stoichiometry: 1.0
species: meta G3P
type: SpeciesReference

meta P3G
is: SBO:0000247
initial amount: NaN
has only substance units: false
name: 3-phosphoglycerate
type: Species
is: CHEBI:17794
initial concentration: 0.117456252783611
constant: false
boundary condition: false
is: C00197
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260017#_3e5c742e_5301_41b8_868c_3d1168c38726
value: 0.0098
type: LocalParameter

meta NADH
in compartment: meta cell
is: SBO:0000247
boundary condition: true
type: Species
name: NADH
is: C00004
has only substance units: false
initial amount: NaN
initial concentration: 0.0867096979846952
is: CHEBI:16908
constant: false

http://identifiers.org/biomodels.db/MODEL1303260017#_9e42b88e_b370_4274_8566_8cd219fe2df7
constant: true
value: 6.02
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260017#a0924179_275b_49e9_9cf2_4e6f37e494f6
value: 0.11
type: LocalParameter

meta PGM1
initial amount: NaN
type: Species
initial concentration: 8.15573865768647E-4
is encoded by: S000001610
is: SBO:0000252
constant: true
boundary condition: true
name: PGM1
has only substance units: false
in compartment: meta cell
is: P33401

http://identifiers.org/biomodels.db/MODEL1303260017#_488e04a1_7dd8_4a4b_8d82_41174d7a8a49
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_45301d82_f71a_4e80_8958_6e853d4eb040
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_958490c9_e784_42b0_b19a_423f9e31f1c4
value: 400.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_287e0284_424d_4004_a2a2_06afdd151b3e
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#ef484d12_87cc_470b_9dce_27cef711f7c7
value: 17.0
type: LocalParameter

meta ENO2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.493611573294543
initial amount: NaN
in compartment: meta cell
name: ENO2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#_7df15dcd_1558_434b_a750_7e4dc3ce5874
value: 21.0
type: LocalParameter

meta PGI1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0345726768225249
initial amount: NaN
in compartment: meta cell
name: PGI1
type: Species

meta UGP1
name: UGP1
constant: true
initial concentration: 0.00155052854965178
is encoded by: S000001518
initial amount: NaN
in compartment: meta cell
boundary condition: true
has only substance units: false
type: Species
is: P32861
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1303260017#bbe9fc31_9bef_49b9_95c2_85afddce2ffb
value: 0.93
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_354e52c1_efa0_4478_b809_81a9b7597246
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#d5cc9476_3eaa_4eab_ae51_1c39901bf04b
stoichiometry: 1.0
species: meta UDP
type: SpeciesReference

meta HXK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0041951864287446
initial amount: NaN
in compartment: meta cell
name: HXK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#_08e8782d_c264_4d89_b892_55510dd65517
value: 90.0
type: LocalParameter

meta PGK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0644142281647388
initial amount: NaN
in compartment: meta cell
name: PGK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#_23a1d6bf_e6be_4cc9_94a8_beefd0bad9e4
stoichiometry: 3.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#f61bc2ed_c139_479d_b152_347d1aa28751
value: 9.3
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_56b4f419_8e32_455d_9617_606d722d432f
value: 0.12762
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_765523a8_09bb_48cd_ba94_c7b1943d9d63
value: 19.87
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_54a9d1b2_23aa_4253_aa9f_6d20c4ccb61e
stoichiometry: 1.0
species: meta F6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#a6aee307_1ffd_4a35_9430_8bf31ef2c206
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_9fa32f84_8c7a_4f56_92d7_998d5aa21204
value: 0.865
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_1fea149e_cea6_46ef_a6d5_9ca4409aff86
value: 3.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_63e2cf58_8b25_4231_8db4_7a6bf28db937
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_7c8926fa_d26b_4e60_98ba_c901e01a62d1
value: 0.423
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#e947f961_061b_4e72_b85d_9f35f999b238
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta HXK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0153328384926289
initial amount: NaN
in compartment: meta cell
name: HXK2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#a97767ce_6070_4b97_a8ce_092f8cb28e0f
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#b9a1f227_1ead_434b_b7d1_5f8dd2af77b1
value: 0.4622
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_06fba159_d2fd_4438_ac93_ee737697c741
units: dimensionless
value: 3200.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_85ebccc0_fb95_4d8f_b365_6bdbe6d37041
value: 21.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_3b59220f_30f3_4624_928d_26abd211a16b
value: 0.023
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#ae5d86bd_e48b_449d_adc5_dd5d485fcdbc
value: 1.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_0e3f7b42_dc2f_41a2_aa2d_94007837aba1
value: 0.909
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_77ddddb5_2175_43b6_a2ad_81fd5d12381a
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

meta EtOH
constant: true
type: Species
is: CHEBI:16236
has only substance units: false
initial amount: NaN
name: ethanol
initial concentration: 55.472577854384
is: SBO:0000247
is: C00469
in compartment: meta cell
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1303260017#_8da2a7c9_da9c_4884_b068_ad8ba7f36fc1
stoichiometry: 1.0
species: meta P2G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#b4b7a99f_88d2_43e8_882b_3ee8bec98390
stoichiometry: 1.0
species: meta P3G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_71a7e332_e00b_4182_b23d_6a0c28e466c1
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_13883ad3_7d91_46f4_9e75_80563958e0b2
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#dbf5916d_93c7_4687_b490_00bcb144d01f
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#c8a28ad2_aab2_471d_ae9a_6f4e79d8988e
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

meta GLY
is: SBO:0000247
boundary condition: true
type: Species
is: CHEBI:17754
initial concentration: 0.15
name: glycerol
is: C00116
constant: true
in compartment: meta cell
has only substance units: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260017#_7bab472f_436d_43ab_919a_2f569a11d398
name: per second
type: SBMLUnitsDef

meta PEP
is: SBO:0000247
type: Species
initial concentration: 0.152501353339511
constant: false
initial amount: NaN
is: C00074
boundary condition: false
is: CHEBI:18021
in compartment: meta cell
name: phosphoenolpyruvate
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260017#_620a9e95_919f_4221_a151_de327a0b40f6
value: 0.023
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_7d197daf_6bb0_450d_b282_b6438957ba26
stoichiometry: 2.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#d4a9d3be_f664_46c0_bac2_c46d5ac4b81a
value: 487.36
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_5aa3f26a_3fca_451d_a4e1_0100ab1cd1b5
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#ba090b23_b346_4b71_ae88_4b417b227e71
stoichiometry: 1.0
species: meta F16bP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_0f0179b4_ab78_4ebb_a67e_2701badfd316
value: 2.4
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_127ff222_adaa_4562_a5fb_8f11b3f0764b
units: dimensionless
value: 2.0
type: LocalParameter

meta PFK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0116962574765781
initial amount: NaN
in compartment: meta cell
name: PFK1
type: Species

meta TDH TDH2
is version of: GO:0004365
fast: false
modifier: MODEL1303260017#
reversible: true
is: R01061
is version of: http://identifiers.org/ec-code/1.2.1.12
type: Reaction
is: SBO:0000176
name: glyceraldehyde phosphate dehydrogenase [TDH2]

http://identifiers.org/biomodels.db/MODEL1303260017#f85d54bd_c437_4372_8c74_40de1b87b525
stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#a87431a0_d8e4_4a6f_b0b6_77f714443685
value: 564.38
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_63e7e87c_1a73_43a8_96a4_c1648b4f56b9
value: 7.08
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_80c72234_b74f_45fd_adb5_5025641abc1d
value: 2.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#b5e386ae_e1b0_4da2_bd44_0b0786f0cd15
modifier: MODEL1303260017#
name: UDP to UTP pseudoreaction
fast: false
type: Reaction
is: SBO:0000176
reversible: false

http://identifiers.org/biomodels.db/MODEL1303260017#_90a23cc4_c8dd_4799_9e09_32d9b157dea2
name: per mM per second
type: SBMLUnitsDef

meta ADH ADH1
is version of: GO:0004022
is version of: http://identifiers.org/ec-code/1.1.1.1
type: Reaction
is: R00754
name: alcohol dehydrogenase [ADH1]
modifier: MODEL1303260017#
fast: false
reversible: true
is: SBO:0000176

meta PYK CDC19
is: R00200
is version of: http://identifiers.org/ec-code/2.7.1.40
name: pyruvate kinase [CDC19]
is: SBO:0000176
reversible: true
type: Reaction
is version of: GO:0004743
modifier: MODEL1303260017#
fast: false

http://identifiers.org/biomodels.db/MODEL1303260017#_082371aa_c6e4_4e42_8e3c_b87b9e3631a1
value: 0.5
type: LocalParameter

meta TDH TDH3
is version of: GO:0004365
is version of: http://identifiers.org/ec-code/1.2.1.12
is: R01061
fast: false
name: glyceraldehyde phosphate dehydrogenase [TDH3]
reversible: true
modifier: MODEL1303260017#
type: Reaction
is: SBO:0000176

meta PFK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00975915538330228
initial amount: NaN
in compartment: meta cell
name: PFK2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#c1444a3f_3493_4d0e_bb43_880cb80ea1b1
stoichiometry: 1.0
species: meta F6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_4dfcb4a5_593c_4d41_84f8_f0a793e0e370
value: 35.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_4096f97d_532e_44b4_87ac_abae6977e025
value: 0.71
type: LocalParameter

meta ADP
constant: false
is: SBO:0000247
has only substance units: false
in compartment: meta cell
initial concentration: 1.29
is: C00008
type: Species
initial amount: NaN
boundary condition: false
name: ADP
is: CHEBI:16761

http://identifiers.org/biomodels.db/MODEL1303260017#f4693432_de00_4761_b576_6a90b33c5e73
value: 0.00549663630823988
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_0ab8f3bb_b5b5_48d8_8fac_09e362364086
stoichiometry: 1.0
species: meta EtOH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_5ba475ee_3054_46d3_aa10_93495cb6c02e
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

meta PYK PYK2
is: R00200
name: pyruvate kinase [PYK2]
type: Reaction
reversible: true
modifier: MODEL1303260017#
is: SBO:0000176
fast: false
is version of: GO:0004743
is version of: http://identifiers.org/ec-code/2.7.1.40

http://identifiers.org/biomodels.db/MODEL1303260017#_8dc2d8a3_7048_4fed_abef_ba8b76d85839
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260017#b7e8d4ce_d500_49e8_847d_d3c8e5e8a1bf
stoichiometry: 1.0
species: meta GLY
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#ef57a55e_5859_48e9_ace4_f26dac250841
value: 0.031
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#abf0f1fc_8c6d_4195_87bb_549445d7e1f5
name: per mmol
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260017#fe283051_df34_469b_90aa_4f4c12f3b058
value: 1.99
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_37cd90b4_ab3b_4047_b39e_d0d82e46d892
units: dimensionless
value: 0.397
type: LocalParameter

meta TRH
is: CHEBI:16551
initial concentration: 0.00384697134241316
is: C01083
in compartment: meta cell
boundary condition: true
constant: true
type: Species
initial amount: NaN
is: SBO:0000247
has only substance units: false
name: trehalose

http://identifiers.org/biomodels.db/MODEL1303260017#_6c2ace08_a5ba_41c2_b738_7ed544f501ee
value: 0.11
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_7c14aad5_b555_4e5d_9154_f0b66c2cb05a
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_79e919eb_6cf3_425d_b37c_dd8eb7730eee
stoichiometry: 1.0
species: meta P2G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#c75d036b_a15f_488b_97c6_f5225a05f868
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#d294b520_544c_4942_9ecb_3a2f14e8866c
stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

meta ENO1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.171592988538958
initial amount: NaN
in compartment: meta cell
name: ENO1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#_507684dc_b773_4df6_a034_27e118af462c
value: 0.783333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_6d8901f4_675c_4633_bf52_dd62b4d32636
value: 0.111
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#e8e5ca1d_7398_42cd_b396_e264a2f13bef
value: 0.0721
type: LocalParameter

meta PYR
initial amount: NaN
boundary condition: false
type: Species
initial concentration: 0.527117851793548
is: CHEBI:15361
is: SBO:0000247
constant: false
name: pyruvate
is: C00022
has only substance units: false
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260017#_75ebec06_ded7_4753_8787_12cdd8a8c46e
value: 0.3
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_76e9bdbd_28cd_4c71_952b_349bfa58d730
stoichiometry: 1.0
species: meta EtOH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_61bc11fa_98c5_45ea_922d_8963ce93e443
stoichiometry: 1.0
species: meta G1P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_063daf8f_79ae_4a50_8d2d_2b68c472765d
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

meta AK
is: R00127
reversible: true
is version of: GO:0004017
is version of: http://identifiers.org/ec-code/2.7.4.3
fast: false
modifier: MODEL1303260017#
is: SBO:0000176
type: Reaction
name: adenylate kinase

http://identifiers.org/biomodels.db/MODEL1303260017#b4473bbc_c81b_4aad_9d74_b29bc0a0a94c
value: 0.00554339592436782
type: LocalParameter

meta TPI
name: triosephosphate isomerase
reversible: true
is version of: http://identifiers.org/ec-code/5.3.1.1
is: SBO:0000176
type: Reaction
is: R01015
fast: false
is version of: GO:0004807
modifier: MODEL1303260017#

meta HXK GLK1
is version of: GO:0004396
name: hexokinase [GLK1]
is: R02848
is: SBO:0000176
reversible: true
fast: false
type: Reaction
modifier: MODEL1303260017#
is version of: http://identifiers.org/ec-code/2.7.1.1

http://identifiers.org/biomodels.db/MODEL1303260017#bd8dbfe5_15c8_407f_af42_76d9d6ad3717
constant: true
value: 1.59
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260017#e21e8158_55a3_4d3b_9413_8b5049c9148d
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta F6P
is: SBO:0000247
type: Species
boundary condition: false
in compartment: meta cell
has only substance units: false
initial concentration: 0.0588603054728053
is: C05345
name: fructose 6-phosphate
initial amount: NaN
constant: false
is: CHEBI:16084

http://identifiers.org/biomodels.db/MODEL1303260017#a55516f9_e74f_4d38_ba6d_5455283e583e
value: 12.14
type: LocalParameter

meta UDG
type: Species
is: CHEBI:18066
is: SBO:0000247
name: UDP glucose
initial amount: NaN
boundary condition: true
initial concentration: 0.467246194874247
in compartment: meta cell
constant: false
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260017#_17066f74_9c9c_4dbd_ab03_851314f899dd
value: 0.09
type: LocalParameter

meta ACE
is: CHEBI:30089
is: SBO:0000247
initial amount: NaN
constant: true
has only substance units: false
name: acetate
boundary condition: true
initial concentration: 55.7500633495734
in compartment: meta cell
type: Species

http://identifiers.org/biomodels.db/MODEL1303260017#e9d400e8_83a9_45fe_8514_90a57fe12732
value: 0.17
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_2ab917df_03c2_4e90_94a9_06b20de326ba
value: 0.09
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#c93d3a4e_2f8f_4932_872d_adc5ed4053b9
value: 0.307
type: LocalParameter

meta P2G
type: Species
is: SBO:0000247
is: C00631
has only substance units: false
initial concentration: 0.0169344770274836
initial amount: NaN
boundary condition: false
constant: false
in compartment: meta cell
name: 2-phosphoglycerate
is: CHEBI:17835

http://identifiers.org/biomodels.db/MODEL1303260017#e75dda5a_bdce_4474_a67a_62680102c17d
value: 19.12
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_7fe45f53_1127_4f48_bd92_bea76bc12b60
value: 13.2552
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_69d655fa_4b94_4559_8f1e_e79a7a7a4ec9
units: dimensionless
value: 0.29
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_885ac2e3_7c6a_4ab0_9e5c_dff2588266e4
value: 0.293
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#f49ab0ac_335c_4e41_9cd2_609469f5b54f
stoichiometry: 1.0
species: meta P2G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#a53ea722_c325_4401_8558_4c693d8bab90
value: 10.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_9e406499_b758_48eb_90e2_458f8a61d18a
value: 0.19
type: LocalParameter

meta ADH ADH5
type: Reaction
name: alcohol dehydrogenase [ADH5]
fast: false
reversible: true
is version of: GO:0004022
is: SBO:0000176
is: R00754
modifier: MODEL1303260017#
is version of: http://identifiers.org/ec-code/1.1.1.1

http://identifiers.org/biomodels.db/MODEL1303260017#c4386471_8c03_4673_8da4_860f5f41f511
value: 90.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_563dccc0_fc70_46a4_98f8_05ce199f7392
value: 4.58
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_34545540_68ed_444c_9a7b_9adae6eb42d0
stoichiometry: 1.0
species: meta G3P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#f9199f5c_01af_4bb0_a825_d1358aab7e04
value: 0.15
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#fd3a2a07_0566_4fd5_9c60_a72318287aa2
constant: true
value: 1.39784619487425
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260017#_7c7cebed_d8cc_4476_8bb2_2335f62b8a92
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_6f6b179e_0c26_4eac_a935_16d73a797214
units: dimensionless
value: 0.0174
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#b8417dba_510a_4a42_b640_102442a3574e
value: 0.9
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#_7e09407f_c464_41ae_9c03_d687e6a22dc2
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#ada6077b_55c7_4c01_bf3e_d446257afeb7
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_2179ab61_27c3_4a55_a594_a76f3256e676
value: 63.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#a86bf64b_3558_45fc_9120_27a272226ed3
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_2652f1f2_924e_4bd3_b10b_a9d0ae6cce61
value: 6.82E-4
type: LocalParameter

meta PDC1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.266952694557084
initial amount: NaN
in compartment: meta cell
name: PDC1
type: Species

meta PDC PDC6
fast: false
modifier: MODEL1303260017#
is: R00636
type: Reaction
is version of: GO:0004737
reversible: false
name: pyruvate decarboxylase [PDC6]
is version of: http://identifiers.org/ec-code/4.1.1.1
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1303260017#f4004575_8ea4_4c79_8f81_1d992e1e44b8
value: 9.21
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#d9251842_55e2_457a_8a71_900884b8208c
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

meta cell
is: GO:0005829
constant: true
size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

http://identifiers.org/biomodels.db/MODEL1303260017#_6c1ccb5a_bd54_4eb4_a3cb_e9d07b5c178d
value: 0.003
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260017#daa355e7_5101_42c3_bb84_40ce19dea099
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_7a2840a1_e9c6_4417_95e8_a402e2b00af1
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260017#_80393d3b_e9e5_4d78_8eec_1f7f900d1f64
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

meta PDC PDC5
is version of: GO:0004737
reversible: false
is: SBO:0000176
name: pyruvate decarboxylase [PDC5]
modifier: MODEL1303260017#
is: R00636
type: Reaction
fast: false
is version of: http://identifiers.org/ec-code/4.1.1.1

http://identifiers.org/biomodels.db/MODEL1303260017#a82ed8da_ee26_43a9_a252_02a4adf92ab3
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

meta GLC
in compartment: meta cell
is: C00031
type: Species
is: CHEBI:4167
initial amount: NaN
is: SBO:0000247
initial concentration: 1.5700004483456
name: glucose
constant: false
boundary condition: false
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260017#_71b62df5_a12e_4dd0_ad0a_cfc19bd4f05f
value: 0.2
type: LocalParameter

orgname: University of Manchester

n:
  given: Kieran
  family: Smallbone