http://identifiers.org/biomodels.db/MODEL1303260015#c59c7e3c_9024_4f7b_93db_94e1f894e230
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_2459af4b_78c5_48c5_b536_7aa577a6ea8d
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

meta PYK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00151748381804475
initial amount: NaN
in compartment: meta cell
name: PYK2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#_5ec91e21_ca08_4e74_aa81_afcc42477554
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_38a44363_86eb_4e97_924d_f33d92b78067
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_06f2391f_19db_4ad3_b080_41db7385d6de
value: 0.54
type: LocalParameter

meta UGP1
is: P32861
type: Species
is encoded by: S000001518
name: UGP1
initial concentration: 0.00155052854965178
boundary condition: true
initial amount: NaN
has only substance units: false
constant: true
in compartment: meta cell
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1303260015#b4ad60cf_5eb6_4829_bef1_ef58db411a46
name: per mM per second
type: SBMLUnitsDef

meta PYK
is version of: GO:0004743
type: Reaction
modifier: MODEL1303260015#
is: R00200
reversible: true
name: pyruvate kinase
is version of: http://identifiers.org/ec-code/2.7.1.40
fast: false
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1303260015#_88d17746_7738_4b01_91e6_e4a75849c4d2
value: 2.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_5d681d90_1f67_43d1_adda_d7a3e3bb57b1
value: 30.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_049d1f54_4c8a_48ce_a26d_dd528cbd0fa0
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

meta GLC
is: SBO:0000247
has only substance units: false
type: Species
in compartment: meta cell
name: glucose
initial concentration: 1.5700004483456
boundary condition: false
is: CHEBI:4167
initial amount: NaN
constant: false
is: C00031

http://identifiers.org/biomodels.db/MODEL1303260015#_1237d05c_e16f_48cb_a910_9779869de1a9
value: 0.003
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_0b7c273e_cbdb_4cc3_b666_9e83bcdad1eb
name: per second
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260015#_7e8e758e_b9f3_40b8_be75_3c47bb3c65a5
value: 30.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#d40eee5a_35a0_49d8_b3ff_54151b53ab0f
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_2b595aa8_ec9b_43c6_813e_9b10b13c31b2
value: 0.307
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_0079242d_6dca_43b0_abc6_c7bc86662f36
value: 1.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_9028c307_2f21_42ce_93de_e395c8154577
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_6021d1b6_3716_4e5d_bd6d_5da57a5b75df
name: mmol
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260015#deaaed7c_7de4_4380_b0ba_8cc3771f1572
constant: true
units: dimensionless
value: 22.0
type: Parameter

meta GPM1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.182500074724267
initial amount: NaN
in compartment: meta cell
name: GPM1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#_18c8190f_367d_4db6_bf06_b0329f488062
value: 0.104
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_7b507543_07aa_4a5c_a50c_139a06d02d9c
stoichiometry: 1.0
species: meta EtOH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#e9745ca7_d137_460f_90fd_9325a2d829c1
value: 1.0
type: LocalParameter

meta TRH
type: Species
boundary condition: true
name: trehalose
is: CHEBI:16551
constant: true
is: SBO:0000247
initial concentration: 0.00384697134241316
initial amount: NaN
is: C01083
has only substance units: false
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260015#_9782830f_e538_46a8_8ebc_8b58736ab19c
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

meta PDC PDC6
is: SBO:0000176
reversible: false
name: pyruvate decarboxylase [PDC6]
is: R00636
is version of: GO:0004737
type: Reaction
is version of: http://identifiers.org/ec-code/4.1.1.1
modifier: MODEL1303260015#
fast: false

http://identifiers.org/biomodels.db/MODEL1303260015#ce75f407_d8ca_443d_bfe6_abba747adc75
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_98856079_78ad_47fa_9a0e_961c4f7e2403
value: 209.6
type: LocalParameter

meta NAD
initial amount: NaN
is: CHEBI:15846
initial concentration: 1.50329030201531
name: NAD
type: Species
is: SBO:0000247
boundary condition: false
in compartment: meta cell
has only substance units: false
constant: false
is: C00003

http://identifiers.org/biomodels.db/MODEL1303260015#f9f2de3e_e889_4c46_9e98_51d6b0e3a0e5
value: 0.65
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#ac881ac4_0088_4e76_a5a0_48c412802cd1
stoichiometry: 1.0
species: meta G1P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_0cbc5c90_85c8_4e2a_be64_c5679c35f64d
value: 10.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#b327a20b_bb1c_4cb9_98e3_e8cae1925d7c
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_727d8836_e6e9_4ba5_be60_26f745f44975
value: 3.8
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#bef75499_2d9e_42a6_871b_79d6429d1759
value: 0.423
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#c63caae6_7452_4f87_8b1f_8b381a3395eb
constant: true
value: 1.39784619487425
type: Parameter

meta PDC PDC5
is version of: GO:0004737
is: SBO:0000176
modifier: MODEL1303260015#
fast: false
is: R00636
name: pyruvate decarboxylase [PDC5]
type: Reaction
is version of: http://identifiers.org/ec-code/4.1.1.1
reversible: false

meta P2G
boundary condition: false
is: CHEBI:17835
name: 2-phosphoglycerate
has only substance units: false
is: C00631
type: Species
constant: false
is: SBO:0000247
in compartment: meta cell
initial concentration: 0.0169344770274836
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260015#e4d55928_a166_4728_9e9a_f8f7723d5543
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_36aab2ce_06a8_438c_b948_de8ba88fdd4e
value: 7500.0
type: LocalParameter

meta TPS1
has only substance units: false
is encoded by: S000000330
initial concentration: 8.48120435592663E-4
boundary condition: true
type: Species
name: TPS1
in compartment: meta cell
constant: true
is: Q00764
is: SBO:0000252
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260015#_11e0fb9a_e54e_4865_ade4_da5a924feba0
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

meta G6P
name: glucose 6-phosphate
in compartment: meta cell
is: C00668
initial amount: NaN
constant: false
boundary condition: false
type: Species
is: CHEBI:17665
is: SBO:0000247
initial concentration: 0.193120800911304
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260015#e92556d6_dbd4_492c_8ae0_ec0276a7b06f
value: 10.32
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#c951d2cc_12d4_4d94_bb27_9271c024841f
value: 0.909
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#f8c7318a_5dca_468a_b6c6_8aa5dcab8fc0
value: 1.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_04645cdc_ddae_47ae_9348_2e95617ca256
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

meta GPP
reversible: false
modifier: MODEL1303260015#
is: R00841
name: glycerol 3-phosphatase
type: Reaction
is: http://identifiers.org/ec-code/3.1.3.21
is: SBO:0000176
fast: false

http://identifiers.org/biomodels.db/MODEL1303260015#_869ed736_03c9_42f9_a6bd_bc6c415eb794
value: 0.023
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#c47d4eb6_54b4_49d7_b036_c13005a6c48e
value: 0.73
type: LocalParameter

meta G1P
initial concentration: 0.13481212658623
is: CHEBI:16077
boundary condition: false
has only substance units: false
initial amount: NaN
name: glucose 1-phosphate
is: SBO:0000247
type: Species
constant: false
in compartment: meta cell

meta GPD1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00170877794272468
initial amount: NaN
in compartment: meta cell
name: GPD1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#_63296fa7_6040_41e3_b7ba_ef3fef0c0a44
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta AMP
constant: false
in compartment: meta cell
name: AMP
is: C00020
is: CHEBI:16027
boundary condition: true
type: Species
initial amount: NaN
initial concentration: 0.44
is: SBO:0000247
has only substance units: false

meta TPS2
in compartment: meta cell
constant: true
boundary condition: true
is: P31688
initial concentration: 6.64962953368736E-4
type: Species
name: TPS2
is: SBO:0000252
initial amount: NaN
is encoded by: S000002481
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260015#_88fc14b8_41df_4d94_8b45_cba2fe9e84c7
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#c0862e96_7ae6_44d0_bc45_8f4efd1d737e
value: 3.35
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#b948ab9b_ef35_4245_9429_66b871d7fc3e
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#b49227c2_8971_4aae_b4ca_6e155851d441
units: dimensionless
value: 100.0
type: LocalParameter

meta RHR2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0127951193429578
initial amount: NaN
in compartment: meta cell
name: RHR2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#f40127d4_5611_46da_abe0_9555a47e9d47
constant: true
value: 6.02
type: Parameter

meta GPD2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.98351416606057E-4
initial amount: NaN
in compartment: meta cell
name: GPD2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#_4f32e479_f04e_4890_80fc_afe533447804
stoichiometry: 1.0
species: meta P2G
type: SpeciesReference

meta GAP
is: CHEBI:29052
in compartment: meta cell
initial concentration: 0.0789727571926259
name: glyceraldehyde 3-phosphate
type: Species
has only substance units: false
boundary condition: false
is: SBO:0000247
constant: false
initial amount: NaN
is: C00118

http://identifiers.org/biomodels.db/MODEL1303260015#a882158a_9824_4ddd_b27b_b789b6703319
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_61870985_3926_40ba_a6f8_e056c55eaffb
value: 9.21
type: LocalParameter

ORG:
  orgname: University of Manchester
n:
  given: Kieran
  family: Smallbone

http://identifiers.org/biomodels.db/MODEL1303260015#_89e6f6b0_b8bd_44da_ac54_6b9a3fc73ffd
constant: true
units: dimensionless
value: 0.00533412710224736
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260015#ebe2a382_2b0e_441f_8b58_59ad361707d3
constant: true
units: dimensionless
value: 6.7
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260015#ebdb6343_aeb9_4572_bba2_92e4788914d7
units: dimensionless
value: 0.1667
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_9541acc9_707a_4821_9ac4_fde514d9a7db
value: 0.00554339592436782
type: LocalParameter

meta PDC PDC1
name: pyruvate decarboxylase [PDC1]
is: R00636
is version of: GO:0004737
modifier: MODEL1303260015#
reversible: false
fast: false
is: SBO:0000176
is version of: http://identifiers.org/ec-code/4.1.1.1
type: Reaction

http://identifiers.org/biomodels.db/MODEL1303260015#_834af77c_1eb5_4fe6_92a2_4e41f5766bda
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

meta GPM
reversible: true
type: Reaction
fast: false
is: SBO:0000176
is version of: GO:0004619
is: R01518
is version of: http://identifiers.org/ec-code/5.4.2.1
name: phosphoglyceromutase
modifier: MODEL1303260015#

meta HXK HXK1
is: R02848
is version of: GO:0004396
type: Reaction
is: SBO:0000176
modifier: MODEL1303260015#
name: hexokinase [HXK1]
is version of: http://identifiers.org/ec-code/2.7.1.1
reversible: true
fast: false

http://identifiers.org/biomodels.db/MODEL1303260015#_56d627a9_3084_4962_86d0_93125a88a683
value: 0.14
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_802b8cd3_9aae_4a03_8864_3c2978079828
stoichiometry: 1.0
species: meta AMP
type: SpeciesReference

meta PGM2
is: SBO:0000252
boundary condition: true
in compartment: meta cell
name: PGM2
initial amount: NaN
initial concentration: 3.1467219294138E-4
constant: true
is encoded by: S000004711
is: P37012
has only substance units: false
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#e82c62eb_5d7e_455a_aca0_742cf0e8be10
units: dimensionless
value: 0.66
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_584a7542_7988_4c5c_9640_e45e11cd0bde
stoichiometry: 1.0
species: meta ACE
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#b9ce0ce8_099b_4eff_8338_aeff66331ede
value: 3.0
type: LocalParameter

meta UDP
in compartment: meta cell
has only substance units: false
boundary condition: false
type: Species
is: SBO:0000247
initial amount: NaN
constant: false
initial concentration: 0.2815
name: UDP
is: CHEBI:17659

http://identifiers.org/biomodels.db/MODEL1303260015#_54b8019e_d0b8_4f72_af4d_a9b2598bbfd9
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

meta PDC1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.266952694557084
initial amount: NaN
in compartment: meta cell
name: PDC1
type: Species

meta GLY
type: Species
boundary condition: true
constant: true
name: glycerol
is: C00116
is: SBO:0000247
initial amount: NaN
initial concentration: 0.15
is: CHEBI:17754
has only substance units: false
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260015#f42f7928_c68a_4309_92c9_1124282316a1
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_53cc7508_cb91_4f59_81ac_39ee4c5bb245
stoichiometry: 1.0
species: meta G3P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#c772769c_f0e2_4c43_83de_04da93d34de7
stoichiometry: 1.0
species: meta F16bP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#c1ce7171_b856_48a7_ac2b_834318f8e0a5
value: 10.0
type: LocalParameter

meta PYR
is: SBO:0000247
constant: false
in compartment: meta cell
name: pyruvate
is: C00022
initial concentration: 0.527117851793548
initial amount: NaN
boundary condition: false
is: CHEBI:15361
has only substance units: false
type: Species

meta FBA
reversible: true
is: SBO:0000176
is version of: GO:0004332
fast: false
name: fructosebisphosphate aldolase
is version of: http://identifiers.org/ec-code/4.1.2.13
is: R01068
type: Reaction
modifier: MODEL1303260015#

http://identifiers.org/biomodels.db/MODEL1303260015#_9ce30647_7ffc_4938_a25a_67fdd7e1f4f8
stoichiometry: 1.0
species: meta P2G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_3c3e0b9c_5882_4d3a_8e37_c94e67151c04
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260015#_67e5f921_028a_4659_b548_99c6ef982aee
stoichiometry: 1.0
species: meta F16bP
type: SpeciesReference

meta GLK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0112717406104807
initial amount: NaN
in compartment: meta cell
name: GLK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#_6abd2f49_1d37_4864_9e6f_91ed49b9328b
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_1597c986_b885_4d67_8135_755436a1894f
value: 1.41
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#ebcb9f40_4a8e_4b5c_a76a_1e6b33eb94ef
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_80af5402_d354_4ac4_aa69_681733ca3feb
value: 0.886
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_3d373189_a50e_447f_9103_d8ab2f15003a
units: dimensionless
value: 0.0845
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_7caa9701_8c2b_49b4_af38_cc128447406e
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

meta ATP
initial concentration: 4.29
in compartment: meta cell
is: CHEBI:15422
is: SBO:0000247
constant: false
has only substance units: false
name: ATP
type: Species
initial amount: NaN
boundary condition: false
is: C00002

http://identifiers.org/biomodels.db/MODEL1303260015#_1a65c0b3_8457_4249_a4ed_3de7af7152d4
value: 0.4507
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_004d0490_50fd_450c_b75e_419d12646707
value: 0.00345026988011002
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_5ff7e36a_cee9_436f_b0c1_b4f17bd23b86
constant: true
value: 6.022140000000001E20
name: Avogadro constant
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260015#_6d2aaab6_894f_4f97_a1bb_6a5c8b45bb12
stoichiometry: 1.0
species: meta GLCx
type: SpeciesReference

meta HXK HXK2
reversible: true
type: Reaction
is version of: http://identifiers.org/ec-code/2.7.1.1
name: hexokinase [HXK2]
modifier: MODEL1303260015#
fast: false
is: SBO:0000176
is: R02848
is version of: GO:0004396

http://identifiers.org/biomodels.db/MODEL1303260015#_6acfaa94_f7a8_4dae_94d3_d7f73dce65e7
value: 0.17
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#c5a80c1d_e970_4b56_808b_55e0b3e3f28d
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#d9b53dc9_7dc0_44b1_88aa_7d64c349e06b
value: 0.75
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#c06ee88d_ba55_42a3_879e_d8a830454102
units: dimensionless
value: 2.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_5a3ba2f1_dcdf_4ba6_81a5_1b10d1078e39
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260015#_8da6258c_7f9c_4740_b132_166eaa25687c
stoichiometry: 1.0
species: meta G3P
type: SpeciesReference

meta PGM1
is encoded by: S000001610
name: PGM1
initial amount: NaN
boundary condition: true
type: Species
constant: true
is: SBO:0000252
in compartment: meta cell
initial concentration: 8.15573865768647E-4
is: P33401
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260015#b70a31fd_cbfc_4306_afbc_9f68935f20f9
value: 0.93
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#a12e53c9_e6fe_440e_8a7e_b99c6e97d47f
stoichiometry: 1.0
species: meta UDG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#db6fcf88_6f66_464b_afba_d8c5d7a00cdf
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

meta ADH1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0409771277320022
initial amount: NaN
in compartment: meta cell
name: ADH1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#ff73dd02_164c_4650_83b3_7f00494dcad0
stoichiometry: 1.0
species: meta F6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_60c6da51_ac21_4195_93bd_e4e146c546b8
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#e1cdf8ea_76b5_420f_97ca_0353df2b63ce
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_81eeb724_7217_4b15_a10f_d0ff24431249
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta PDC6
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0016352160527653
initial amount: NaN
in compartment: meta cell
name: PDC6
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#_67283239_80bf_4637_a1ba_ea5984d3d057
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta HXT
is: SBO:0000185
is version of: GO:0015758
type: Reaction
modifier: MODEL1303260015#
fast: false
name: glucose transport
reversible: true

http://identifiers.org/biomodels.db/MODEL1303260015#b8af66fc_84da_409d_bf3f_538bcfc6b9b0
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#a37b2e99_6609_42e3_8858_55b5c71169e8
value: 3.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#b1c86ebd_adb1_4b3e_b674_593f0874862f
value: 0.09
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_40f55e55_515f_4dcb_bb53_f1e89fb17e97
stoichiometry: 1.0
species: meta UTP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_5451f3d3_46d1_46ea_92d4_50d47ab9909b
stoichiometry: 0.75
species: meta SUC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_8ee4549d_4ee4_42ba_be75_112bb7ff0159
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#b2c0b629_a253_4eec_a3a7_5f5bb5aa51a6
stoichiometry: 1.0
species: meta G1P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_2eb8323c_bb2e_4866_bf2d_c9d584ea35ba
value: 0.09
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_4d5ae7eb_6e81_48be_ad85_16ccbd5ccd86
value: 19.12
type: LocalParameter

meta AcAld
type: Species
has only substance units: false
name: acetaldehyde
is: CHEBI:15343
initial amount: NaN
is: SBO:0000247
boundary condition: false
is: C00084
constant: false
in compartment: meta cell
initial concentration: 0.178140579850657

http://identifiers.org/biomodels.db/MODEL1303260015#_9c8d29f5_44ce_4406_8580_6f7f0d0e5cb5
value: 1.99
type: LocalParameter

meta PDC5
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00308868608169189
initial amount: NaN
in compartment: meta cell
name: PDC5
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#_7476d2bc_d940_4826_99a1_664d67890423
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_51446e27_9faa_4263_9cec_7b1a9d71a95f
value: 2.4
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#b4e7d05b_9eda_461f_8d0d_36bfefd787e8
stoichiometry: 1.0
species: meta UDG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_371545e1_124f_4495_9f12_cdd03f63afd2
constant: false
value: NaN
name: glycerate phosphates
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260015#_40a90773_612d_4eab_9ccd_b742a5150263
value: 63.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_0b58dd0d_348d_4262_9bec_56f24a880061
name: mM per second
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260015#db63f407_88b8_4cf7_8ef9_1e3e9297d86a
value: 2.92
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_0a810a43_a0ff_443a_8792_4a54b46ad250
units: dimensionless
value: 6500.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_4ca82075_ffd1_494b_8647_cf7b0cc819f2
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260015#_3ba2e749_3f80_4542_bc84_93debeb2160b
value: 17.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#e75a8fdf_c9eb_45bb_84c6_f6baa654d18b
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_781c2342_d3b8_41e3_87d2_8e608d5e0a58
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#faac5413_bff2_4e28_81bc_61af67f5f3fb
exponent: -1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260015#_49ff75f8_5c4e_49b5_a8f2_08748ce9835f
stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#e5493fb0_b814_46c1_bdef_d5837d629bc5
value: 0.06
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_3ca2ccca_1cc6_4767_819a_b22a824b45be
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_2f981001_2c41_49b2_b069_6e062258f77e
value: 0.0995
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#e71105a9_3622_4e6d_aa7e_27f5387cd1b0
value: 0.06
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#c425fe4b_0166_4adf_94ee_ecd825b9e239
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#e4e0ceea_b70d_4af1_9f39_5661755632ad
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_9c0476d2_04f9_4701_88e4_4279ebb0becc
value: 0.031
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#b4c46a47_6e6b_417d_89c9_d0cb5133c935
value: 0.17
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#fc77651e_7b38_44df_b04b_98f0cc438033
value: 1.13333333333333
type: LocalParameter

meta PEP
is: CHEBI:18021
type: Species
in compartment: meta cell
has only substance units: false
boundary condition: false
constant: false
name: phosphoenolpyruvate
is: C00074
initial amount: NaN
is: SBO:0000247
initial concentration: 0.152501353339511

http://identifiers.org/biomodels.db/MODEL1303260015#_38d495fe_4edd_4027_a6c9_c299504d4423
constant: false
units: dimensionless
value: NaN
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260015#_1db2337e_ebd2_4524_ae0b_a0c529256238
value: 1.1
type: LocalParameter

meta DHAP
is: CHEBI:16108
constant: false
boundary condition: false
initial amount: NaN
is: C00111
is: SBO:0000247
in compartment: meta cell
type: Species
has only substance units: false
initial concentration: 0.290344213186674
name: dihydroxyacetone phosphate

http://identifiers.org/biomodels.db/MODEL1303260015#_92e978ae_c834_4b93_aba1_beb331f562b2
value: 19.87
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_28092e7d_dad5_44e7_86b0_cb722a320329
value: 58.6
type: LocalParameter

meta UTP
has only substance units: false
is: SBO:0000247
constant: false
is: CHEBI:46398
type: Species
initial amount: NaN
boundary condition: false
in compartment: meta cell
name: UTP
initial concentration: 0.6491

meta TPI1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.073589454911377
initial amount: NaN
in compartment: meta cell
name: TPI1
type: Species

meta F6P
is: CHEBI:16084
in compartment: meta cell
is: SBO:0000247
type: Species
initial concentration: 0.0588603054728053
name: fructose 6-phosphate
boundary condition: false
initial amount: NaN
has only substance units: false
constant: false
is: C05345

http://identifiers.org/biomodels.db/MODEL1303260015#a278a562_d461_46d6_bd28_77ef1bfacf7e
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_551a323d_0807_4223_996e_b1f257b052e9
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#e7000d8c_cc71_4c9d_9f23_c3286aa688e8
stoichiometry: 1.0
species: meta P3G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_68af1688_516d_4842_adb6_49cd145e65ab
value: 1.0257
type: LocalParameter

meta ADH5
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00106249605621922
initial amount: NaN
in compartment: meta cell
name: ADH5
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#_53d17b24_5511_472b_9bab_a66acd678d28
value: 400.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_8176a300_1e18_47c4_b4eb_819713944590
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_9f27c586_46c6_4831_bd00_4d509053ccb6
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#d81ac7d7_4c2e_4823_b239_9861fcac7986
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#e63e89b6_8b0b_49a8_9194_9fb582c2fae8
stoichiometry: 1.0
species: meta UDP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#f8bd307d_da10_460e_827f_b3766a7f83b1
value: 0.783333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_949b35e0_2937_4b61_9f15_72d5ecd45e20
value: 17.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#c72181a3_8300_4a8f_b876_2f3118cd771a
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#ec7cf798_4a0b_47bf_9fd9_d0441586434b
constant: true
units: dimensionless
value: 14492.7536231884
type: Parameter

meta ADH ADH1
is version of: http://identifiers.org/ec-code/1.1.1.1
modifier: MODEL1303260015#
is: R00754
name: alcohol dehydrogenase [ADH1]
is version of: GO:0004022
reversible: true
type: Reaction
is: SBO:0000176
fast: false

meta PGI
is: SBO:0000176
is: R00771
modifier: MODEL1303260015#
is version of: GO:0004347
is version of: http://identifiers.org/ec-code/5.3.1.9
type: Reaction
reversible: true
fast: false
name: phosphoglucose isomerase

http://identifiers.org/biomodels.db/MODEL1303260015#a37dc36e_a261_4546_b030_7d7db61acf84
stoichiometry: 1.0
species: meta TRH
type: SpeciesReference

meta TPI
is: SBO:0000176
name: triosephosphate isomerase
reversible: true
fast: false
is version of: http://identifiers.org/ec-code/5.3.1.1
type: Reaction
is version of: GO:0004807
is: R01015
modifier: MODEL1303260015#

http://identifiers.org/biomodels.db/MODEL1303260015#_4f0bc3e2_d9e4_4ccf_bcdd_751b501d5f9c
value: 0.53
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_92d20bb3_6405_44cc_bb13_2a345b9a8548
name: mM
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260015#_73ceb68a_bfaf_4ca4_8e32_3a9e1d7b15b7
value: 176.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_2b4a0ee0_4ead_4e5b_bd50_d8b14d600115
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_9b18b498_2cf9_4c75_b823_2183b3b9a398
value: 1.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_90fd1b24_9f69_4f80_8836_458eaacd1feb
units: dimensionless
value: 0.397
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_0d289f6e_4177_4437_8156_b9c4446d8a47
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

meta PFK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0116962574765781
initial amount: NaN
in compartment: meta cell
name: PFK1
type: Species

meta NADH
boundary condition: true
has only substance units: false
type: Species
name: NADH
is: SBO:0000247
initial concentration: 0.0867096979846952
is: C00004
initial amount: NaN
in compartment: meta cell
is: CHEBI:16908
constant: false

http://identifiers.org/biomodels.db/MODEL1303260015#af24b83d_1d79_45cc_a32e_219d432c99a8
value: 4.58
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#ada98702_4b7c_4ea5_8f61_75111449df1e
value: 7.08
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#ce6f54f7_f8c4_4f25_ac5e_97f2462c9566
value: 0.11
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_8458d504_28e0_4fcd_9632_ca5759392f80
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#bfa240d9_862d_4d3f_a862_3326586d6302
value: 0.23
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_51062714_e14c_4354_9ade_2c9ba02d1ebe
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

meta ADH ADH5
modifier: MODEL1303260015#
is: SBO:0000176
is version of: http://identifiers.org/ec-code/1.1.1.1
reversible: true
type: Reaction
is version of: GO:0004022
name: alcohol dehydrogenase [ADH5]
is: R00754
fast: false

http://identifiers.org/biomodels.db/MODEL1303260015#_5f250600_3cf0_4511_80fb_ef20cf9d551b
stoichiometry: 1.0
species: meta P2G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#ffe435fc_b3a0_4202_bd5d_7e47027eb8c9
units: dimensionless
value: 10000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_4a9ab324_4f4e_4e93_92bc_ea2bbd3ff739
value: 0.92
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_01aa5134_b634_4dda_a551_cb0c6218b15f
value: 0.0106
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#cf5cfab6_0668_430a_9cf4_69463721cdda
value: 0.11
type: LocalParameter

meta PFK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00975915538330228
initial amount: NaN
in compartment: meta cell
name: PFK2
type: Species

meta PGK
is: R01512
type: Reaction
is version of: GO:0004618
fast: false
modifier: MODEL1303260015#
name: 3-phosphoglycerate kinase
reversible: true
is version of: http://identifiers.org/ec-code/2.7.2.3
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1303260015#_4dce6807_6f0d_4cb1_a06c_7056bb59fe05
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_390ade82_ca72_44c7_a77f_944f78f32d78
value: 16.6666666666667
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#dd855b7f_7610_4899_8db3_6ab728508d09
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

meta HXK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0153328384926289
initial amount: NaN
in compartment: meta cell
name: HXK2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#ec5ff729_6445_425f_b3ef_3cdb194b0ca5
value: 0.09
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_7bb63753_3117_4058_9dfb_770ae9cca509
stoichiometry: 1.0
species: meta T6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#ba3d57fa_5b76_46be_90c7_e7b320efde24
value: 0.23
type: LocalParameter

meta GPD
is: R00842
is: SBO:0000176
is: http://identifiers.org/ec-code/1.1.1.94
modifier: MODEL1303260015#
name: glycerol 3-phosphate dehydrogenase
reversible: true
fast: false
type: Reaction

http://identifiers.org/biomodels.db/MODEL1303260015#_6418f984_b08b_4ff7_b90e_3785ff649b07
value: 0.92
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_1b128b3c_fb24_4b62_b8bb_aeb710305cd2
value: 12.14
type: LocalParameter

meta PFK
fast: false
type: Reaction
is version of: GO:0003872
is version of: http://identifiers.org/ec-code/2.7.1.11
reversible: false
modifier: MODEL1303260015#
is: SBO:0000176
name: phosphofructokinase
is: R00756

http://identifiers.org/biomodels.db/MODEL1303260015#d850cde8_e256_40a5_8a24_b1c6364a26fe
constant: true
units: dimensionless
value: 2000.0
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260015#_0956a766_2de7_4f80_9d18_5b6e0efa4963
value: 4.139
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_867a90fb_a4e0_4263_9722_aa3cbb372408
value: 0.043
type: LocalParameter

meta UDG
initial concentration: 0.467246194874247
has only substance units: false
in compartment: meta cell
type: Species
name: UDP glucose
initial amount: NaN
constant: false
boundary condition: true
is: SBO:0000247
is: CHEBI:18066

meta TDH TDH1
name: glyceraldehyde phosphate dehydrogenase [TDH1]
is version of: GO:0004365
fast: false
is: SBO:0000176
reversible: true
is version of: http://identifiers.org/ec-code/1.2.1.12
type: Reaction
modifier: MODEL1303260015#
is: R01061

meta HXK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0041951864287446
initial amount: NaN
in compartment: meta cell
name: HXK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#f355869f_cf9f_468f_b1cb_94fd41ea27dd
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_4d7e4f4b_3c4f_4450_b4af_6f8936a28dde
constant: true
value: 1.59
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260015#_7702ea92_4d86_4bf2_8147_1e3d385f833c
units: dimensionless
value: 5.12
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#c4ad79b2_8794_4853_a812_20f9c8b48f22
value: 487.36
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_284e96af_9b69_4a7c_b501_0e0df093e6b8
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_06c2b4ef_f0e6_4de4_81b1_8e4f155d4d7e
stoichiometry: 2.0
species: meta ADP
type: SpeciesReference

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units: dimensionless
value: 0.29
type: LocalParameter

meta ADP
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in compartment: meta cell
is: CHEBI:16761
constant: false
name: ADP
initial concentration: 1.29
is: C00008
has only substance units: false
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initial amount: NaN

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constant: false
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value: NaN
type: Parameter

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stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

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value: 0.2
type: LocalParameter

meta cell
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constant: true
size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

meta TDH3
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boundary condition: true
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initial concentration: 1.05110118662137
initial amount: NaN
in compartment: meta cell
name: TDH3
type: Species

meta PGM
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fast: false
reversible: true
type: Reaction
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is version of: http://identifiers.org/ec-code/5.4.2.2

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species: meta BPG
type: SpeciesReference

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value: 0.069
type: LocalParameter

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value: 8.633
type: LocalParameter

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name: glyceraldehyde phosphate dehydrogenase [TDH3]
type: Reaction
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modifier: MODEL1303260015#

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stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

meta T6P
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initial amount: NaN
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is: SBO:0000247
is: CHEBI:18283
boundary condition: false
constant: false
in compartment: meta cell

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value: 0.11
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exponent: -1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
species: meta PYR
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value: 0.613666666666667
type: LocalParameter

W3 CDTF: Sun Nov 09 00:00:00 GMT 2008

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value: 0.111
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value: 0.77
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meta extracellular
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constant: true
size: 1.0
spatial dimensions: 3.0
name: extracellular
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stoichiometry: 3.0
species: meta NADH
type: SpeciesReference

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value: 1.11
type: LocalParameter

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value: 0.0035
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meta BPG
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in compartment: meta cell
constant: false
boundary condition: false
is: C00236
initial amount: NaN
initial concentration: 7.36873499865602E-4

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value: 0.0721
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#d8dc7c6a_caf4_43eb_b027_01065be01f83
value: 21.0
type: LocalParameter

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value: 4.8
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meta UGP
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fast: false
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name: adenylate kinase
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meta PGI1
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initial concentration: 0.0345726768225249
initial amount: NaN
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value: 0.4622
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value: 0.06
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meta TPP
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reversible: false
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units: dimensionless
value: 0.19
type: LocalParameter

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value: 0.293
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#bbddee4e_4c98_41d9_b690_0522e47c6e27
value: 0.05
type: LocalParameter

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units: dimensionless
value: 0.045
type: LocalParameter

meta ENO ENO1
is version of: http://identifiers.org/ec-code/4.2.1.11
is: SBO:0000176
type: Reaction
reversible: true
is version of: GO:0004634
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fast: false
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units: dimensionless
value: 3.0
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units: dimensionless
value: 3200.0
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value: 0.11
type: LocalParameter

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stoichiometry: 1.0
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meta EtOH
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initial concentration: 55.472577854384
is: SBO:0000247
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meta PGK1
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meta GLCx
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name: glucose
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type: SBMLUnit

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value: 8.5
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value: 0.0098
type: LocalParameter

meta ENO ENO2
modifier: MODEL1303260015#
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type: Reaction
reversible: true
is: R00658
is version of: http://identifiers.org/ec-code/4.2.1.11
is version of: GO:0004634
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fast: false

http://identifiers.org/biomodels.db/MODEL1303260015#_4ec0dbbc_65e8_4073_859d_e9aa44c27fa2
value: 0.9
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_60174843_ad4b_4896_bbaa_1a1348d6e68d
constant: true
units: litre
value: 2.0E-14
name: volume
type: Parameter

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value: 90.0
type: LocalParameter

meta P3G
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initial amount: NaN
name: 3-phosphoglycerate
is: SBO:0000247
type: Species
constant: false
is: C00197
initial concentration: 0.117456252783611
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in compartment: meta cell

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value: 2.0
type: LocalParameter

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value: 0.031
type: LocalParameter

meta ENO1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.171592988538958
initial amount: NaN
in compartment: meta cell
name: ENO1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#fdc8ce65_59d8_4232_a237_50035f9ec1b6
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#b38d862e_a853_49e8_868a_b84c294e90ed
units: dimensionless
value: 0.0174
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#a05cbdfd_08ca_4564_b071_fd1877a2cf83
exponent: 1.0
scale: -3
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kind: MOLE
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meta FBA1
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in compartment: meta cell
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stoichiometry: 1.0
species: meta F6P
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stoichiometry: 1.0
species: meta AcAld
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meta ATPase
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fast: false
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type: Reaction
name: ATPase

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value: 0.023
type: LocalParameter

meta ENO2
is: SBO:0000252
constant: true
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initial concentration: 0.493611573294543
initial amount: NaN
in compartment: meta cell
name: ENO2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#_5de5d84c_86dc_451e_a553_39ef49aef683
value: 6.82E-4
type: LocalParameter

meta TDH2
is: SBO:0000252
constant: true
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initial concentration: 0.0
initial amount: NaN
in compartment: meta cell
name: TDH2
type: Species

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value: 0.00590833333333333
type: LocalParameter

meta SUC
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name: succinate
is: CHEBI:30031
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type: Species

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units: dimensionless
value: 0.45
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meta G3P
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name: glycerol 3-phosphate
is: SBO:0000247
has only substance units: false
in compartment: meta cell
type: Species
constant: false
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is: C00093
initial amount: NaN

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stoichiometry: 1.0
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type: SpeciesReference

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value: 0.883333333333333
type: LocalParameter

meta acetate branch
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is: SBO:0000176
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is version of: GO:0006105
type: Reaction
name: acetate branch
reversible: false

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value: 0.71
type: LocalParameter

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value: 0.108333333333333
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meta TDH1
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in compartment: meta cell
name: TDH1
type: Species

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value: 18.162
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_5530c60e_3482_4b71_90dc_90750782a802
value: 0.865
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http://identifiers.org/biomodels.db/MODEL1303260015#_5e1ee3e4_4c78_4c0a_91c2_520d01723030
value: 0.04
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http://identifiers.org/biomodels.db/MODEL1303260015#_5c65ad10_9f0d_4c71_a74a_310f50197d71
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meta F26bP
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is: SBO:0000247
is: CHEBI:28602
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initial concentration: 0.003

meta succinate branch
is version of: GO:0006105
is: SBO:0000176
type: Reaction
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name: succinate branch
fast: false

MODEL1303260015
name: reversible mass action
species: meta TPS2
name: Hill kinetics
species: meta UTP
species: meta EtOH
reaction: meta TPP
species: meta TDH2
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initial assignment: MODEL1303260015#
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species: meta GLC
reaction: meta HXK HXK1
species: meta NAD
species: meta PGM2
species: meta GLK1
species: meta PYR
is: http://identifiers.org/taxonomy/4932
name: HXK inhibition by T6P
name: irreversible michaelis-menten: one substrate, no product
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species: meta RHR2
species: meta AMP
compartment: meta extracellular
species: meta PGK1
name: reversible michaelis-menten: ordered uni-bi
name: irreversible michaelis-menten: two substrates, no products
species: meta AcAld
reaction: meta PFK
species: meta PFK1
species: meta F26bP
name: reversible michaelis-menten: ordered bi-bi
species: meta DHAP
species: meta ADH1
reaction: meta TPS
reaction: meta PDC PDC5
reaction: meta AK
species: meta PDC5
compartment: meta cell
species: meta GLCx
reaction: meta TDH TDH3
curated: false
species: meta PDC1
species: meta TRH
type: SBMLModel
species: meta T6P
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reaction: meta PGI
species: meta PEP
name: facilitated diffusion: symmetrical carrier
species: meta P3G
species: meta TDH1
name: phosphofructokinase kinetics with Keq
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species: meta PGM1
species: meta TPI1
species: meta PDC6
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name: reversible michaelis-menten: one substrate, one product
name: reversible michaelis-menten: two substrates, two products, three inhibitors, non-competitive inhibition
species: meta HOR2
species: meta FBA1
name: phosphoglycerate kinase kinetics
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species: meta TDH3
notes: Smallbone2013 - Glycolysis in S.cerevisiae - Iteration 15 This model is described in the article: A model of yeast glycolysis based on a consistent kinetic characterization of all its enzymes Kieran Smallbone, Hanan L. Messiha, Kathleen M. Carroll, Catherine L. Winder, Naglis Malys, Warwick B. Dunn, Ettore Murabito, Neil Swainston, Joseph O. Dada, Farid Khan, Pınar Pir, Evangelos Simeonidis, Irena Spasić, Jill Wishart, Dieter Weichart, Neil W. Hayes, Daniel Jameson, David S. Broomhead, Stephen G. Oliver, Simon J. Gaskell, John E.G. McCarthy, Norman W. Paton, Hans V. Westerhoff, Douglas B. Kell, Pedro Mendes FEBS Letters (in press) Abstract: We present an experimental and computational pipeline for the generation of kinetic models of metabolism, and demonstrate its application to glycolysis in Saccharomyces cerevisiae. Starting from an approximate mathematical model, we employ a “cycle of knowledge” strategy, identifying the steps with most control over flux. Kinetic parameters of the individual isoenzymes within these steps are measured experimentally under a standardised set of conditions. Experimental strategies are applied to establish a set of in vivo concentrations for isoenzymes and metabolites. The data are integrated into a mathematical model that is used to predict a new set of metabolite concentrations and reevaluate the control properties of the system. This bottom-up modelling study reveals that control over the metabolic network most directly involved in yeast glycolysis is more widely distributed than previously thought. This model is hosted on BioModels Database and identified by: MODEL1303260015 . To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models . To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more …
species: meta PGI1
species: meta SUC
reaction: meta ADH ADH5
species: meta ADH5
reaction: meta GPM
species: meta ENO2
reaction: meta HXK GLK1
species: meta G6P

http://identifiers.org/biomodels.db/MODEL1303260015#cb7288a4_5990_431e_ade0_6a45408e34d3
fast: false
is: SBO:0000176
type: Reaction
reversible: false
modifier: MODEL1303260015#
name: UDP to UTP pseudoreaction

meta F16bP
in compartment: meta cell
is: SBO:0000247
is: C05378
name: fructose 1,6-bisphosphate
has only substance units: false
initial amount: NaN
is: CHEBI:28013
initial concentration: 1.14580464751733
constant: false
boundary condition: false
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#_28acf4a2_8689_46e1_8368_3d1c39ac7482
value: 0.195
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_1dc4c1e8_9f50_4e01_8e26_c94bc846d539
value: 0.00549663630823988
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#a3b43989_4185_46b5_b1b7_c5584a954993
stoichiometry: 3.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_90b7c2de_530d_4295_88d7_9514fa88f319
value: 90.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_71d705f7_de7c_441d_b9a4_43e4dbd50e73
value: 0.23
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_30b3f2ae_fb1a_4569_8c9a_be67449a8b6a
units: dimensionless
value: 800.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_752e4192_417f_4dcf_baec_f19018a45b9e
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#cf898eff_a514_4177_ae65_cd8507d72ef1
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260015#_3788a0d1_3c3a_4186_a5f4_1d28e793e772
value: 0.15
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_2b5ab195_92bf_4823_865d_ce80ec859766
stoichiometry: 1.0
species: meta EtOH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#b0530376_3005_43a3_ba93_4738d0cbbdca
value: 0.32
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_64309d46_04e9_433f_b1da_6ad76d5064d1
value: 0.02285
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#cfbc9b83_c0a2_4efd_a757_f3e3c0214227
value: 30.0
type: LocalParameter

meta CDC19
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.512097526792801
initial amount: NaN
in compartment: meta cell
name: CDC19
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#_27a45bcd_9090_421d_8cd3_71e3a4df8035
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#e456f696_739f_41b9_b4c4_806030ac8dc8
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_28968ea3_a64e_4f4e_9ea8_1defaf4d6cf9
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#cd213a2f_513f_448a_a564_3c82aa1972a8
stoichiometry: 1.0
species: meta P3G
type: SpeciesReference

meta TPS
is: SBO:0000176
reversible: false
modifier: MODEL1303260015#
is version of: http://identifiers.org/ec-code/2.4.1.15
type: Reaction
fast: false
name: T6P synthase

http://identifiers.org/biomodels.db/MODEL1303260015#_2b6366d4_768f_48c6_9653_b914314471ab
value: 1.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#_4092d46f_a45e_4fe3_84f2_04e7e51c1910
name: per mmol
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260015#_064bb2cd_62ad_4a03_b4b2_ee423f8f182c
units: dimensionless
value: 0.91
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#bc252987_d567_4db9_8e8f_b50cd42b9f92
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta HXK GLK1
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.7.1.1
modifier: MODEL1303260015#
name: hexokinase [GLK1]
reversible: true
type: Reaction
is version of: GO:0004396
fast: false
is: R02848

http://identifiers.org/biomodels.db/MODEL1303260015#c6c91b04_74b1_4d38_87a0_54704e8312e4
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_9eb23edd_018a_4625_9233_0c8c119b53ac
value: 0.495
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260015#fa1bdc03_9b61_41cd_a7da_c39e2e1a6421
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_925584a6_47c8_4fb0_8f91_6b8cb21c4c6f
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_34c3db80_18d0_408b_aaf7_cca3086bfb7c
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260015#_3d2f9b60_f05c_4d06_9e23_6a0dae1f1e96
value: 0.0098
type: LocalParameter

meta HOR2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0013683673909939
initial amount: NaN
in compartment: meta cell
name: HOR2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260015#_8653054e_3d67_4aef_860f_6a9613a2519a
value: 7.6
type: LocalParameter

meta ACE
type: Species
initial concentration: 55.7500633495734
constant: true
is: CHEBI:30089
boundary condition: true
name: acetate
has only substance units: false
initial amount: NaN
in compartment: meta cell
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1303260015#_5ebf7b28_930e_4a9c_a9a4_ab6eb9a3bb0d
value: 0.5
type: LocalParameter

W3 CDTF: Wed Nov 14 14:34:59 GMT 2012