http://identifiers.org/biomodels.db/MODEL1303260008#_997d891d_e089_402f_9215_6fefb5b68bcc
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#a5dda954_5913_472b_9196_8a6c4f2b8feb
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

meta PYR
name: pyruvate
initial concentration: 0.527117851793548
has only substance units: false
initial amount: NaN
is: C00022
is: CHEBI:15361
boundary condition: false
in compartment: meta cell
constant: false
is: SBO:0000247
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#_625f3ac6_b1c8_46ff_8837_fc40cec5c6a1
value: 0.65
type: LocalParameter

meta PFK
name: phosphofructokinase
reversible: false
is: SBO:0000176
modifier: MODEL1303260008#
is: R00756
type: Reaction
is version of: http://identifiers.org/ec-code/2.7.1.11
is version of: GO:0003872
fast: false

http://identifiers.org/biomodels.db/MODEL1303260008#_31dfb7a4_dcad_4fa7_b15b_5eec2d8f3578
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#d1c08f8d_a99d_4505_aa72_9e00c593cf07
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta GLK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0112717406104807
initial amount: NaN
in compartment: meta cell
name: GLK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#_13c4fd7e_1079_4117_9e5c_a7ec577923b4
name: per mmol
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260008#_371e7518_4a76_457b_acb9_21e8539ef0a4
value: 0.53
type: LocalParameter

meta TPI
reversible: true
is version of: GO:0004807
fast: false
is version of: http://identifiers.org/ec-code/5.3.1.1
is: R01015
modifier: MODEL1303260008#
type: Reaction
is: SBO:0000176
name: triosephosphate isomerase

http://identifiers.org/biomodels.db/MODEL1303260008#_20252218_9cbd_43c0_a535_9aabf80d2260
value: 259.220125786164
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#df20d048_a9f8_441c_904e_080883a4ad70
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_08ec6183_57fe_4e06_be28_42e5b303ff90
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_5945aaad_bd9c_4780_82ef_3a6ff4daf8c0
value: 1.4
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#d3e9062d_bc9c_4d39_afd1_1ae21214d538
stoichiometry: 1.0
species: meta UDP
type: SpeciesReference

meta P3G
constant: false
is: CHEBI:17794
is: C00197
boundary condition: false
name: 3-phosphoglycerate
in compartment: meta cell
initial amount: NaN
has only substance units: false
is: SBO:0000247
type: Species
initial concentration: 0.117456252783611

http://identifiers.org/biomodels.db/MODEL1303260008#a000916f_8e64_4059_b6aa_954f943a6ecf
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_2fe01932_c99d_4745_a25f_82404d737190
value: 0.04
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#b98569cc_4978_40e3_8cac_8daee596f06b
value: 0.17
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#a28b0459_aea8_4011_9622_196fd74ca338
value: 0.23
type: LocalParameter

meta HXK GLK1
is version of: GO:0004396
is: R02848
type: Reaction
reversible: true
is: SBO:0000176
fast: false
name: hexokinase [GLK1]
modifier: MODEL1303260008#
is version of: http://identifiers.org/ec-code/2.7.1.1

http://identifiers.org/biomodels.db/MODEL1303260008#_8926c86e_9372_4264_86da_de56480174a6
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_2f3c63b9_cbb4_470d_9544_9f9769e671a0
units: dimensionless
value: 6500.0
type: LocalParameter

meta GPD
modifier: MODEL1303260008#
type: Reaction
reversible: true
is: R00842
name: glycerol 3-phosphate dehydrogenase
is: SBO:0000176
fast: false
is: http://identifiers.org/ec-code/1.1.1.94

http://identifiers.org/biomodels.db/MODEL1303260008#ef2be82f_ccaa_439b_a360_3673861e8197
value: 7.08
type: LocalParameter

meta PGM
reversible: true
fast: false
is: SBO:0000176
modifier: MODEL1303260008#
type: Reaction
is version of: http://identifiers.org/ec-code/5.4.2.2
name: phosphoglucomutase

http://identifiers.org/biomodels.db/MODEL1303260008#ab4bc502_70a8_4d15_9eaf_c16c6720f347
value: 0.11
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_44c298ee_7205_4e34_b255_66318fe68d13
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

meta PGM2
initial concentration: 3.1467219294138E-4
type: Species
in compartment: meta cell
name: PGM2
has only substance units: false
is: SBO:0000252
boundary condition: true
constant: true
is: P37012
initial amount: NaN
is encoded by: S000004711

meta TPP
modifier: MODEL1303260008#
fast: false
is: SBO:0000176
reversible: false
name: T6P phosphatase
is version of: http://identifiers.org/ec-code/3.1.3.12
type: Reaction

meta T6P
in compartment: meta cell
is: CHEBI:18283
name: trehalose 6-phosphate
initial concentration: 0.02
constant: false
boundary condition: false
initial amount: NaN
type: Species
is: SBO:0000247
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260008#_64e107d4_c86a_4d6a_9a20_81ccde092f3b
value: 209.6
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_90f5f8e3_5401_4879_a14f_4273ad63112d
value: 0.111
type: LocalParameter

meta GLCx
is: C00031
is: CHEBI:4167
name: glucose
type: Species
initial concentration: 74.0
initial amount: NaN
boundary condition: true
in compartment: meta extracellular
constant: true
has only substance units: false
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1303260008#_0d3ba04e_30a3_46d9_a08b_856abd6cefd0
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#c3a30bc7_fc48_4a3c_bc67_bb67bf6ccd83
value: 0.003
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#be051755_91dd_4658_8af4_4e6d6a40b147
value: 0.71
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_5d5e390d_5433_44b4_9b2f_64d2b2f96389
stoichiometry: 1.0
species: meta P3G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_43bdfae5_c372_4ec4_809e_018de5a8d0c8
value: 16.6666666666667
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_5898add9_806b_4367_baeb_c21556216b94
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

meta P2G
initial amount: NaN
initial concentration: 0.0169344770274836
in compartment: meta cell
is: CHEBI:17835
boundary condition: false
is: C00631
has only substance units: false
name: 2-phosphoglycerate
type: Species
is: SBO:0000247
constant: false

meta PGK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0644142281647388
initial amount: NaN
in compartment: meta cell
name: PGK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#c78e0479_8a38_4b22_a346_c3f10eec04e8
units: dimensionless
value: 3200.0
type: LocalParameter

meta PGM1
boundary condition: true
in compartment: meta cell
is: SBO:0000252
name: PGM1
is encoded by: S000001610
constant: true
initial concentration: 8.15573865768647E-4
type: Species
is: P33401
initial amount: NaN
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260008#a6c850cc_5f8d_43fd_8ff1_c1168a1f2f73
value: 0.32
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_06865229_bf06_4796_b251_dbe11b177ac0
constant: false
value: NaN
name: glycerate phosphates
type: Parameter

meta PDC1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.266952694557084
initial amount: NaN
in compartment: meta cell
name: PDC1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#_462bd27d_e017_480c_a299_9358b50c1f82
value: 0.06
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#bf18b501_1302_4ed1_bc5d_01ace8cd8d9f
value: 30.0
type: LocalParameter

meta TPS2
is encoded by: S000002481
type: Species
initial concentration: 6.64962953368736E-4
has only substance units: false
boundary condition: true
initial amount: NaN
in compartment: meta cell
name: TPS2
is: SBO:0000252
constant: true
is: P31688

http://identifiers.org/biomodels.db/MODEL1303260008#e2a54d6c_3f03_44b9_aa0a_e2c67384a2e8
stoichiometry: 2.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_14aad317_072a_4183_b6ee_3dab6e3b718c
value: 0.04
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#bb32f537_31c8_4d86_b8e9_e2ef874fc57c
value: 2.4
type: LocalParameter

meta cell
is: GO:0005829
constant: true
size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

meta PGK
is version of: GO:0004618
fast: false
name: 3-phosphoglycerate kinase
is: R01512
reversible: true
modifier: MODEL1303260008#
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.7.2.3
type: Reaction

http://identifiers.org/biomodels.db/MODEL1303260008#_40a85412_2521_4125_900b_69e259f78425
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#db32c4b4_7681_4bc9_9c77_1b04d1015d14
units: dimensionless
value: 0.1667
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_4dcbe87b_950e_4786_aaae_31018c3bba7b
value: 8.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_29e4cc64_4003_425a_b175_7180908fee5d
stoichiometry: 1.0
species: meta UDG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_0a60f4c3_22a9_4852_92e0_f8934aa96b2e
value: 0.9
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_175c13ba_1cfd_4be3_8671_b4f421467ce8
value: 0.069
type: LocalParameter

meta GPM1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.182500074724267
initial amount: NaN
in compartment: meta cell
name: GPM1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#a910a43f_66e7_4638_b6a4_5a829eb86f7b
stoichiometry: 1.0
species: meta G3P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#a402ab35_25df_44f7_8d81_f81e693fc11a
value: 19.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#a00c363c_8195_4cff_9764_e8b28bbb6325
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#f2dd4a2c_d9e8_42c8_9570_903ba2f123ee
units: dimensionless
value: 0.00533412710224736
type: LocalParameter

meta FBA1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0367018202831552
initial amount: NaN
in compartment: meta cell
name: FBA1
type: Species

meta PGI
name: phosphoglucose isomerase
fast: false
reversible: true
modifier: MODEL1303260008#
is version of: http://identifiers.org/ec-code/5.3.1.9
is version of: GO:0004347
is: R00771
is: SBO:0000176
type: Reaction

http://identifiers.org/biomodels.db/MODEL1303260008#d9f9cadc_57e4_460b_9617_d1b6edba1851
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260008#_6d3fe461_c15f_4316_a1c0_bbbbbb046bdb
value: 0.02285
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#e44cb1b9_7126_41ee_b579_47010fe12167
value: 0.00554339592436782
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_9611d4b5_80f1_4d14_bab8_d650ed89a0a0
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260008#_127164fc_8748_4c71_91d3_2d8d4f64a870
units: dimensionless
value: 0.45
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_5bf9ee77_be25_4259_9eec_49788c8430ae
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_820e963b_70ef_4700_ac86_16e743909b39
units: dimensionless
value: 5.12
type: LocalParameter

meta ADH1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0409771277320022
initial amount: NaN
in compartment: meta cell
name: ADH1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#c3b6bffc_257f_4cf9_b26c_3c677c4b6366
stoichiometry: 1.0
species: meta F6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#bba04654_eb0e_457a_8a64_fa652016277b
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260008#ce789d87_ad61_4d11_bac6_53051b04e648
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_2103914f_78cb_416e_8832_9e9a58c9fba8
value: 21.0
type: LocalParameter

meta TPS1
name: TPS1
is encoded by: S000000330
is: SBO:0000252
is: Q00764
type: Species
in compartment: meta cell
initial concentration: 8.48120435592663E-4
has only substance units: false
constant: true
boundary condition: true
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260008#b4346de0_6b8b_4eee_a8e6_b99957ebe2b3
units: dimensionless
value: 14492.7536231884
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_470adb16_5601_43e9_9379_6e74d0561a92
value: 1.11
type: LocalParameter

meta TPI1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.073589454911377
initial amount: NaN
in compartment: meta cell
name: TPI1
type: Species

meta TPS
modifier: MODEL1303260008#
is version of: http://identifiers.org/ec-code/2.4.1.15
reversible: false
is: SBO:0000176
name: T6P synthase
type: Reaction
fast: false

http://identifiers.org/biomodels.db/MODEL1303260008#_5ab99466_bc54_4a86_8fac_c76a21879692
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_9fa265e5_a4f0_4afd_9711_616661c11aba
value: 0.883333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_10260488_fcf4_4df3_9bd6_3ee3e9285cd7
stoichiometry: 1.0
species: meta UDP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#bd10a123_5794_428e_87f2_109551b891ad
value: 10.32
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_174ed930_71f0_46af_ae02_7d2db2c3e716
stoichiometry: 1.0
species: meta AMP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_5c0fac2d_bcd4_4ac7_bd50_87633dbececb
value: 0.293
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_502238a9_ea0a_40ee_940e_f38fc6dcb845
value: 3.8
type: LocalParameter

meta GPD1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00170877794272468
initial amount: NaN
in compartment: meta cell
name: GPD1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#a919ce62_d042_4d87_ad3b_4049374d8ee1
value: 9.21
type: LocalParameter

meta HXT
reversible: true
type: Reaction
name: glucose transport
modifier: MODEL1303260008#
is version of: GO:0015758
fast: false
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1303260008#_1af73526_948b_46df_80d7_cbe831c63345
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#ce713cff_9285_4146_a141_f4f327107a6d
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#a50c854b_caa4_493a_b562_40ae3c23ebc0
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#dea12d9d_cd41_45ba_910e_5a84a096fd4f
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#dc0e2f0e_136c_4ef0_955e_0cb40eb6ad24
stoichiometry: 1.0
species: meta GLY
type: SpeciesReference

meta PEP
initial amount: NaN
initial concentration: 0.152501353339511
is: SBO:0000247
type: Species
constant: false
in compartment: meta cell
name: phosphoenolpyruvate
boundary condition: false
has only substance units: false
is: CHEBI:18021
is: C00074

meta GPD2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.98351416606057E-4
initial amount: NaN
in compartment: meta cell
name: GPD2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#caf5d759_6832_474b_ac84_c6790d9f03c8
value: 3.35
type: LocalParameter

meta BPG
has only substance units: false
constant: false
is: SBO:0000247
boundary condition: false
name: 1,3-bisphosphoglycerate
initial concentration: 7.36873499865602E-4
is: CHEBI:16001
type: Species
in compartment: meta cell
is: C00236
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260008#a7fd84e9_d094_4eb0_b842_b62b3afeb54b
stoichiometry: 3.0
species: meta NAD
type: SpeciesReference

meta GLY
initial amount: NaN
boundary condition: true
name: glycerol
has only substance units: false
is: C00116
is: CHEBI:17754
is: SBO:0000247
type: Species
in compartment: meta cell
initial concentration: 0.15
constant: true

http://identifiers.org/biomodels.db/MODEL1303260008#_8c864380_abdd_423c_ad2c_82cfa13a5ee8
stoichiometry: 1.0
species: meta F16bP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_1e67dc17_1c4e_4e5d_a865_b531616736d3
name: per second
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260008#_0ad98a78_8436_4514_ae95_30e1db2f1ab3
constant: true
value: 6.022140000000001E20
name: Avogadro constant
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260008#_849454d1_2358_41b2_9778_95586500c2dd
value: 0.05
type: LocalParameter

meta HXK HXK1
type: Reaction
is: SBO:0000176
is: R02848
reversible: true
fast: false
is version of: http://identifiers.org/ec-code/2.7.1.1
modifier: MODEL1303260008#
is version of: GO:0004396
name: hexokinase [HXK1]

http://identifiers.org/biomodels.db/MODEL1303260008#b8df9c92_0d46_42d0_b73e_03e0d7847e0a
stoichiometry: 1.0
species: meta G1P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#bdaa8677_896b_4d05_9baa_8e96f02f0fc2
value: 2.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_7a23c69b_d9a0_4062_b491_3c663dabe5c5
name: mmol
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260008#_4858335b_a7f7_48a4_a62d_3863c8fe2eeb
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

meta succinate branch
name: succinate branch
is version of: GO:0006105
modifier: MODEL1303260008#
fast: false
type: Reaction
is: SBO:0000176
reversible: false

http://identifiers.org/biomodels.db/MODEL1303260008#_3ba0d07e_1cda_43c8_8dc6_27a909638876
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_2f5c7279_c5c4_4e56_8457_ca1c7c7307ca
constant: true
units: dimensionless
value: 38.8857
type: Parameter

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value: 43.0833333333333
type: LocalParameter

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stoichiometry: 1.0
species: meta NAD
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value: 0.2
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meta HXK HXK2
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is version of: http://identifiers.org/ec-code/2.7.1.1
modifier: MODEL1303260008#
name: hexokinase [HXK2]
is version of: GO:0004396
fast: false
type: Reaction
is: SBO:0000176
is: R02848

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value: 0.00345026988011002
type: LocalParameter

meta FBA
name: fructosebisphosphate aldolase
type: Reaction
modifier: MODEL1303260008#
fast: false
is: SBO:0000176
is version of: http://identifiers.org/ec-code/4.1.2.13
is version of: GO:0004332
reversible: true
is: R01068

meta G6P
initial concentration: 0.193120800911304
constant: false
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boundary condition: false
is: SBO:0000247
is: CHEBI:17665
has only substance units: false
initial amount: NaN
in compartment: meta cell

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stoichiometry: 1.0
species: meta ADP
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value: 0.92
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units: dimensionless
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stoichiometry: 1.0
species: meta ADP
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type: SpeciesReference

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value: 0.3
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stoichiometry: 3.0
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stoichiometry: 1.0
species: meta NADH
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stoichiometry: 1.0
species: meta F16bP
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value: 0.023
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value: 0.00590833333333333
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meta ATP
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constant: false
is: C00002
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boundary condition: false
initial amount: NaN
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species: meta GLC
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units: dimensionless
value: 0.397
type: LocalParameter

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stoichiometry: 1.0
species: meta AcAld
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stoichiometry: 1.0
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value: 1.0
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meta ENO2
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constant: true
boundary condition: true
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initial concentration: 0.493611573294543
initial amount: NaN
in compartment: meta cell
name: ENO2
type: Species

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value: 0.3
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_80350635_0fa7_4e06_8a59_1497097d303b
value: 90.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_726c798d_1bb8_4a70_a84a_d7a231b6224a
value: 1.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_38979c7f_2920_4421_9be0_da49a23f104b
value: 0.54
type: LocalParameter

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units: dimensionless
value: 3.0
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value: 10.0
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units: dimensionless
value: 800.0
type: LocalParameter

meta ADP
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in compartment: meta cell
name: ADP
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type: Species
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boundary condition: false
initial concentration: 1.29
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has only substance units: false

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stoichiometry: 1.0
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initial concentration: 0.171592988538958
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constant: true
units: dimensionless
value: 2000.0
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260008#b8f1e735_0d1f_422b_8426_15d3bedeb257
value: 17.6
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#c67edb45_ef4a_47e1_8c51_69e8c8d6f82c
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_7752c135_9150_41f0_9ef9_16c8374a8e1e
stoichiometry: 1.0
species: meta T6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_655b723a_9709_4ca4_ab69_b371eb122601
value: 6.82E-4
type: LocalParameter

meta SUC
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type: Species
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initial amount: NaN
boundary condition: true
name: succinate
constant: true
is: C00042
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is: CHEBI:30031

http://identifiers.org/biomodels.db/MODEL1303260008#_28a38735_6049_402e_a8ca_473a8a3fddb5
stoichiometry: 1.0
species: meta UDG
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stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

meta UGP1
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initial amount: NaN
is encoded by: S000001518
is: SBO:0000252
constant: true
in compartment: meta cell
boundary condition: true
initial concentration: 0.00155052854965178
is: P32861
type: Species
name: UGP1

http://identifiers.org/biomodels.db/MODEL1303260008#a07ab8a6_008b_4997_bd37_0735978aad18
units: dimensionless
value: 0.0845
type: LocalParameter

meta GLC
in compartment: meta cell
name: glucose
type: Species
initial amount: NaN
is: C00031
constant: false
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initial concentration: 1.5700004483456
boundary condition: false
is: CHEBI:4167
is: SBO:0000247

meta F16bP
has only substance units: false
initial amount: NaN
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type: Species
name: fructose 1,6-bisphosphate
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constant: false
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is: CHEBI:28013
is: C05378

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units: dimensionless
value: 10000.0
type: LocalParameter

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exponent: 1.0
scale: 0
multipler: 1.0
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http://identifiers.org/biomodels.db/MODEL1303260008#_4aab1fa1_5a8d_4ea3_86a4_7374a3a172b7
value: 1.57816666666667
type: LocalParameter

meta PDC PDC5
name: pyruvate decarboxylase [PDC5]
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reversible: false
type: Reaction
is: SBO:0000176
is version of: http://identifiers.org/ec-code/4.1.1.1
is version of: GO:0004737
modifier: MODEL1303260008#
is: R00636

http://identifiers.org/biomodels.db/MODEL1303260008#_367305e4_e908_4d82_ad36_c7e3718a1625
value: 0.14
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_359a09f2_4a20_4cc3_b01b_2e297efc2d42
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#cdb37f5f_f671_412f_b676_646967d91d41
stoichiometry: 1.0
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stoichiometry: 1.0
species: meta ATP
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meta F6P
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is: SBO:0000247
constant: false
name: fructose 6-phosphate
in compartment: meta cell
initial amount: NaN
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is: C05345

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value: 0.0098
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stoichiometry: 1.0
species: meta EtOH
type: SpeciesReference

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value: 0.783333333333333
type: LocalParameter

meta ENO
reversible: true
name: enolase
modifier: MODEL1303260008#
is version of: GO:0004634
is version of: http://identifiers.org/ec-code/4.2.1.11
fast: false
type: Reaction
is: SBO:0000176
is: R00658

http://identifiers.org/biomodels.db/MODEL1303260008#_9377c235_29c5_4061_87b0_a102bb42d1d7
value: 0.886
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meta DHAP
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constant: false
type: Species
is: C00111
is: SBO:0000247
initial amount: NaN
is: CHEBI:16108
name: dihydroxyacetone phosphate
initial concentration: 0.290344213186674
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has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260008#_383c95e0_8473_4436_9add_0d3c7f6d6986
value: 30.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#e3db9d55_4fbd_4039_b824_668facb023ce
name: mM per second
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260008#_54164b55_4c46_44b8_adc5_05fd33447dce
value: 0.11
type: LocalParameter

meta UGP
is version of: http://identifiers.org/ec-code/2.7.7.9
modifier: MODEL1303260008#
fast: false
name: UDP glucose phosphorylase
type: Reaction
is: SBO:0000176
reversible: false

http://identifiers.org/biomodels.db/MODEL1303260008#_5d5e2bbc_a69f_44e5_94f7_b63cc6dfd7fc
stoichiometry: 1.0
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meta AcAld
constant: false
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name: acetaldehyde
is: SBO:0000247
is: CHEBI:15343
has only substance units: false
is: C00084
type: Species
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initial amount: NaN

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units: dimensionless
value: 0.19
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value: 0.865
type: LocalParameter

meta extracellular
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constant: true
size: 1.0
spatial dimensions: 3.0
name: extracellular
type: Compartment

MODEL1303260008
reaction: meta ADH
name: min
is: http://identifiers.org/taxonomy/4932
reaction: meta PGK
reaction: meta PFK
reaction: meta AK
species: meta PFK1
species: meta G1P
reaction: meta PDC PDC1
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species: meta PFK2
species: meta PDC6
species: meta UTP
species: meta F16bP
name: irreversible mass action
name: reversible mass action
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species: meta HXK1
name: phosphofructokinase kinetics with Keq
reaction: meta PGI
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species: meta G6P
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reaction: meta GPD
species: meta NAD
name: max
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species: meta GPM1
reaction: meta TPI
species: meta P2G
species: meta PGI1
species: meta TDH3
reaction: meta succinate branch
species: meta UDG
species: meta TPI1
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reaction: meta HXT
species: meta ADP
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species: meta G3P
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species: meta UDP
species: meta ENO1
species: meta EtOH
reaction: meta acetate branch
species: meta TDH1
species: meta F6P
name: reversible michaelis-menten: two substrates, two products, three inhibitors, non-competitive inhibition
species: meta ENO2
name: HXK inhibition by T6P
initial assignment: MODEL1303260008#
reaction: meta ENO
reaction: meta HXK HXK2
species: meta RHR2
species: meta FBA1
species: meta TDH2
species: meta PGK1
species: meta GAP
name: UGP kinetics
compartment: meta cell
name: facilitated diffusion: symmetrical carrier
species: meta GLY
species: meta AcAld
notes: Smallbone2013 - Glycolysis in S.cerevisiae - Iteration 08 This model is described in the article: A model of yeast glycolysis based on a consistent kinetic characterization of all its enzymes Kieran Smallbone, Hanan L. Messiha, Kathleen M. Carroll, Catherine L. Winder, Naglis Malys, Warwick B. Dunn, Ettore Murabito, Neil Swainston, Joseph O. Dada, Farid Khan, Pınar Pir, Evangelos Simeonidis, Irena Spasić, Jill Wishart, Dieter Weichart, Neil W. Hayes, Daniel Jameson, David S. Broomhead, Stephen G. Oliver, Simon J. Gaskell, John E.G. McCarthy, Norman W. Paton, Hans V. Westerhoff, Douglas B. Kell, Pedro Mendes FEBS Letters (in press) Abstract: We present an experimental and computational pipeline for the generation of kinetic models of metabolism, and demonstrate its application to glycolysis in Saccharomyces cerevisiae. Starting from an approximate mathematical model, we employ a “cycle of knowledge” strategy, identifying the steps with most control over flux. Kinetic parameters of the individual isoenzymes within these steps are measured experimentally under a standardised set of conditions. Experimental strategies are applied to establish a set of in vivo concentrations for isoenzymes and metabolites. The data are integrated into a mathematical model that is used to predict a new set of metabolite concentrations and reevaluate the control properties of the system. This bottom-up modelling study reveals that control over the metabolic network most directly involved in yeast glycolysis is more widely distributed than previously thought. This model is hosted on BioModels Database and identified by: MODEL1303260008 . To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models . To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more …
species: meta AMP
species: meta TRH
species: meta BPG
species: meta ADH1
species: meta T6P
reaction: meta PYK
species: meta GLC
species: meta ACE
type: SBMLModel

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value: 0.1
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constant: true
units: litre
value: 2.0E-14
name: volume
type: Parameter

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value: 7500.0
type: LocalParameter

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units: dimensionless
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value: 0.195
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value: 1.1
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value: 3.0
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meta acetate branch
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name: acetate branch
fast: false
reversible: false
is: SBO:0000176
type: Reaction
modifier: MODEL1303260008#

meta PDC PDC6
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fast: false
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name: pyruvate decarboxylase [PDC6]
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is: R00636
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is version of: GO:0004737
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meta ACE
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initial concentration: 55.7500633495734
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meta PGI1
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in compartment: meta cell
name: PGI1
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value: 0.23
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value: 0.023
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meta GAP
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type: Species
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name: glyceraldehyde 3-phosphate
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http://identifiers.org/biomodels.db/MODEL1303260008#_53120043_42da_4e01_ac00_44c0325f0935
value: 1.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_88ad559e_f58f_4e1f_9900_72c68fa30e37
value: 0.031
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http://identifiers.org/biomodels.db/MODEL1303260008#e972c584_1cbd_4feb_8612_78bbe83845e4
stoichiometry: 1.0
species: meta ATP
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meta TRH
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constant: true
initial concentration: 0.00384697134241316
in compartment: meta cell
is: C01083
initial amount: NaN
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http://identifiers.org/biomodels.db/MODEL1303260008#b6c108ec_8ba7_43f2_840e_aa000f503eba
value: 63.1
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meta F26bP
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initial concentration: 0.003
is: CHEBI:28602
name: fructose 2,6-bisphosphate
constant: true
is: C00665
is: SBO:0000247
initial amount: NaN
in compartment: meta cell
type: Species

meta PYK
type: Reaction
is version of: http://identifiers.org/ec-code/2.7.1.40
modifier: MODEL1303260008#
is: SBO:0000176
name: pyruvate kinase
is: R00200
reversible: true
fast: false
is version of: GO:0004743

http://identifiers.org/biomodels.db/MODEL1303260008#_876b2c32_b654_46b3_98f1_bdf2fab1b1b0
value: 0.15
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_21c5eb7b_3535_4b2e_b239_6d37613173db
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#b086afa1_4944_4327_9107_11c6f748d133
value: 0.108333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#ea247591_5885_4ca2_9c90_e11d65785aca
stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#f7d41f71_5b21_489c_a3cf_13452f12cedc
constant: true
value: 1.59
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260008#fe7e93ad_7e6d_4731_961b_40786ce5053c
name: mM
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260008#d0977544_842a_40a3_9ecb_73bf907c993e
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

meta UTP
type: Species
initial amount: NaN
is: SBO:0000247
has only substance units: false
constant: false
is: CHEBI:46398
in compartment: meta cell
name: UTP
boundary condition: false
initial concentration: 0.6491

http://identifiers.org/biomodels.db/MODEL1303260008#d35032ff_db5a_4c96_8577_23582a039849
value: 0.08
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#fa1f2bd8_9c88_4880_ad0c_71e6cccf03c6
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#aee61d67_f2af_47f6_9031_9f64f2e442f1
units: dimensionless
value: 0.66
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#c6916ef9_9336_4b2d_819a_adf30bd440a2
value: 0.613666666666667
type: LocalParameter

meta RHR2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0127951193429578
initial amount: NaN
in compartment: meta cell
name: RHR2
type: Species

meta GPP
type: Reaction
is: R00841
is: SBO:0000176
name: glycerol 3-phosphatase
is: http://identifiers.org/ec-code/3.1.3.21
fast: false
modifier: MODEL1303260008#
reversible: false

http://identifiers.org/biomodels.db/MODEL1303260008#ec994df5_168f_4b14_a92c_e49e5be9c8ed
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta NAD
type: Species
constant: false
has only substance units: false
in compartment: meta cell
boundary condition: false
initial concentration: 1.50329030201531
name: NAD
initial amount: NaN
is: CHEBI:15846
is: C00003
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1303260008#_9662f222_f108_4a00_aa4c_39f4b5aab0f4
stoichiometry: 1.0
species: meta UTP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_7efb4aad_7a6a_4f6c_9929_dd130c8a4a9c
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260008#_44dc991b_c7cb_4ea0_b34c_0605c2268e5d
value: 1.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_834c000d_08c6_4d6f_b4d2_a26a9ba9cb8f
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_141f5578_9010_46a0_b488_256c08e337f2
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#f6b119b3_9514_46eb_9eb3_781cd8c1ba1f
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta UDP
initial amount: NaN
initial concentration: 0.2815
boundary condition: false
has only substance units: false
is: CHEBI:17659
in compartment: meta cell
constant: false
name: UDP
type: Species
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1303260008#bf960787_b1ed_48b8_9aa3_b6ced87b7461
stoichiometry: 1.0
species: meta F6P
type: SpeciesReference

meta HOR2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0013683673909939
initial amount: NaN
in compartment: meta cell
name: HOR2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#_2de47b3d_0ce0_4e74_9e74_71ba8622c182
value: 12.14
type: LocalParameter

meta PDC6
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0016352160527653
initial amount: NaN
in compartment: meta cell
name: PDC6
type: Species

meta PFK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0116962574765781
initial amount: NaN
in compartment: meta cell
name: PFK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#_6653851c_05b9_42d3_a1c2_25524dbc6127
value: 0.11
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#a4629c38_8ffd_455a_bff9_2f414561f6a8
value: 0.73
type: LocalParameter

meta ATPase
type: Reaction
is version of: GO:0016887
fast: false
is: SBO:0000176
modifier: MODEL1303260008#
name: ATPase
reversible: false

http://identifiers.org/biomodels.db/MODEL1303260008#_5554045e_cc3a_4a33_8e27_b957c65ecb7e
value: 2.92
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_428aa816_6422_45c7_a1ce_7f76735bf95a
value: 0.53
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_6c726cfb_2ef5_4950_b33c_da81d9fef8b4
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260008#a0ff6fb9_5707_4f05_bace_5df62d7f5597
modifier: MODEL1303260008#
type: Reaction
fast: false
is: SBO:0000176
reversible: false
name: UDP to UTP pseudoreaction

http://identifiers.org/biomodels.db/MODEL1303260008#b15e3d65_4244_41f8_acd2_fb489c0b440d
value: 0.5
type: LocalParameter

meta PDC5
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00308868608169189
initial amount: NaN
in compartment: meta cell
name: PDC5
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#_79f4ea55_c06e_449f_925a_9e09cf481b1a
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260008#_516d741d_4cd8_4777_91aa_1d94b48ba759
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta CDC19
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.512097526792801
initial amount: NaN
in compartment: meta cell
name: CDC19
type: Species

meta ADH
name: alcohol dehydrogenase
type: Reaction
reversible: true
fast: false
is: R00754
is: SBO:0000176
is version of: http://identifiers.org/ec-code/1.1.1.1
modifier: MODEL1303260008#
is version of: GO:0004022

http://identifiers.org/biomodels.db/MODEL1303260008#a1e69b5d_eaee_4f61_8599_adbb6cd8969f
exponent: -1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260008#_622a57ff_b599_4e7f_8cf2_f3b1b1d3caeb
value: 0.0721
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_24de79b5_a1c1_49de_8433_a32d8ed37df7
constant: true
value: 1.39784619487425
type: Parameter

meta NADH
is: C00004
is: CHEBI:16908
constant: false
boundary condition: true
name: NADH
is: SBO:0000247
has only substance units: false
initial concentration: 0.0867096979846952
initial amount: NaN
in compartment: meta cell
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#_78dda587_6f10_41c0_bd52_d098dc531ff9
constant: true
value: 6.02
type: Parameter

meta TDH1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.087716160700349
initial amount: NaN
in compartment: meta cell
name: TDH1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#b00338db_f985_4706_b530_1e10299ae356
value: 0.0995
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_289121cc_41a9_47c9_87c3_efc4a602b1b8
stoichiometry: 1.0
species: meta P2G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#b73e93f5_3fa8_4a30_9c77_420f0bc0f9a0
constant: false
units: dimensionless
value: NaN
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260008#_206d8d4f_94f5_4483_858b_c0feaa6ec380
value: 1.13333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_706a2922_2818_45cc_8162_3434bbb5798c
constant: false
units: dimensionless
value: NaN
type: Parameter

meta ADH5
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00106249605621922
initial amount: NaN
in compartment: meta cell
name: ADH5
type: Species

meta G3P
initial amount: NaN
boundary condition: false
constant: false
name: glycerol 3-phosphate
is: C00093
is: SBO:0000247
initial concentration: 0.068500732297821
is: CHEBI:15978
has only substance units: false
in compartment: meta cell
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#_68cc705c_be9b_461c_a587_2f3cf0273802
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_94933b31_e438_4bd9_b3db_64dbf6a23eff
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_75d87e93_f771_482e_911f_c944eb8da222
units: dimensionless
value: 0.0174
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_951b6293_8e75_4222_b3a3_1f62a212f5ad
exponent: -1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

meta GPM
reversible: true
name: phosphoglyceromutase
modifier: MODEL1303260008#
is version of: GO:0004619
type: Reaction
is: SBO:0000176
is: R01518
fast: false
is version of: http://identifiers.org/ec-code/5.4.2.1

http://identifiers.org/biomodels.db/MODEL1303260008#c99d02da_cb93_4f2f_9da2_069e6a07a400
value: 111.334973497906
type: LocalParameter

meta G1P
in compartment: meta cell
name: glucose 1-phosphate
initial amount: NaN
is: SBO:0000247
type: Species
constant: false
is: CHEBI:16077
initial concentration: 0.13481212658623
has only substance units: false
boundary condition: false

meta AK
fast: false
name: adenylate kinase
modifier: MODEL1303260008#
is version of: http://identifiers.org/ec-code/2.7.4.3
type: Reaction
is: SBO:0000176
reversible: true
is: R00127
is version of: GO:0004017

http://identifiers.org/biomodels.db/MODEL1303260008#_9d2ff6b3_ec3c_4443_9d90_716a3bbe0b45
name: per mM per second
type: SBMLUnitsDef

meta TDH3
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.05110118662137
initial amount: NaN
in compartment: meta cell
name: TDH3
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#b890739e_e3f8_4fc0_be4c_048e0bf117c3
value: 30.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#ebb7ce55_69ac_48e1_a6ec_97415fbe34f7
stoichiometry: 1.0
species: meta G1P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_4349343a_cd96_447b_8060_7d8a13e7a051
value: 10.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#aa490076_e133_466e_a56e_dbe7775ccd5c
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_8bddf624_c361_49a1_8402_bffc1c110272
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

meta PYK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00151748381804475
initial amount: NaN
in compartment: meta cell
name: PYK2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#_341db142_5def_4376_b83f_93df112146e8
value: 0.75
type: LocalParameter

meta PDC PDC1
reversible: false
is version of: GO:0004737
is version of: http://identifiers.org/ec-code/4.1.1.1
is: SBO:0000176
name: pyruvate decarboxylase [PDC1]
type: Reaction
fast: false
is: R00636
modifier: MODEL1303260008#

meta TDH2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: meta cell
name: TDH2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#_9d237b7c_cae8_439e_981c_775a6e10eb36
value: 0.21
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_26894763_a237_401e_8ff0_11c297a6aecb
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#d8bc36a9_1313_4856_a7cd_4193174b5abf
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_372114e4_99d7_4dbc_90bc_2d11c5c1d167
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_022f805e_e991_4f36_abc8_b8df293db8ee
value: 0.3
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_6ea96f44_5fbd_4b58_a02b_16c01dd0604e
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

meta EtOH
is: C00469
type: Species
boundary condition: true
constant: true
is: CHEBI:16236
initial amount: NaN
in compartment: meta cell
name: ethanol
has only substance units: false
initial concentration: 55.472577854384
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1303260008#fb06bb80_43c3_4dd0_af43_44f849a316f4
stoichiometry: 0.75
species: meta SUC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_3a465ffb_9004_48e8_86e0_c32e0cf3ec4a
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#ec15af2d_ec72_4cd2_8b50_3cd325a226cc
units: dimensionless
value: 0.045
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#fd0ea2e5_e534_404e_ae56_df3edd0c8a1e
value: 0.23
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_9723558a_7ebf_4d1a_8327_dea210cb4b2b
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_67947b35_fafc_4a5c_978c_62223b627e14
value: 3.36
type: LocalParameter

meta HXK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0153328384926289
initial amount: NaN
in compartment: meta cell
name: HXK2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#da3f87d8_7cd4_4226_ba72_d5932692b836
units: dimensionless
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#ee703e22_659b_4782_ae57_2349409a6738
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

meta TDH
is version of: http://identifiers.org/ec-code/1.2.1.12
reversible: true
fast: false
is version of: GO:0004365
is: SBO:0000176
modifier: MODEL1303260008#
is: R01061
type: Reaction
name: glyceraldehyde phosphate dehydrogenase

http://identifiers.org/biomodels.db/MODEL1303260008#cb36e452_b6b8_4dd6_aa2e_6fb9a79edfe2
stoichiometry: 1.0
species: meta T6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_3ef879e1_72b7_4368_b792_3baa55f62adc
value: 2.0
type: LocalParameter

meta AMP
name: AMP
is: C00020
constant: false
is: SBO:0000247
initial concentration: 0.44
has only substance units: false
initial amount: NaN
type: Species
is: CHEBI:16027
boundary condition: true
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260008#cd6d083a_54d9_4072_8da7_ee7abbda9877
value: 0.93
type: LocalParameter

meta PFK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00975915538330228
initial amount: NaN
in compartment: meta cell
name: PFK2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#bd6d5450_ef6e_49ed_a243_428ca5649c45
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260008#_15c929e6_983a_47a1_86f9_151b27587dd6
value: 3.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260008#_77c674e7_ecdd_4235_9267_9fbf864955f9
units: dimensionless
value: 6.7
type: LocalParameter

meta HXK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0041951864287446
initial amount: NaN
in compartment: meta cell
name: HXK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260008#_00783d80_0590_488b_94d3_42a6c391a463
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260008#_4ec11b07_772c_4908_92d3_4b5e2fca2b3e
value: 17.0
type: LocalParameter

meta UDG
is: CHEBI:18066
name: UDP glucose
initial concentration: 0.467246194874247
initial amount: NaN
is: SBO:0000247
in compartment: meta cell
has only substance units: false
type: Species
constant: false
boundary condition: true

ORG:
  orgname: University of Manchester
n:
  given: Kieran
  family: Smallbone

W3 CDTF: Sun Nov 09 00:00:00 GMT 2008

W3 CDTF: Wed Nov 14 14:34:56 GMT 2012