http://identifiers.org/biomodels.db/MODEL1303260004#_6acf190b_dfc6_48a9_a59c_9f626b1e75c4
value: 0.15
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_8ec30a54_5b2c_43a0_b778_099836e79afa
constant: false
units: dimensionless
value: NaN
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260004#d22b2faa_d0e1_4876_97f5_64a59bf86379
stoichiometry: 3.0
species: meta NADH
type: SpeciesReference

meta TPI1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.073589454911377
initial amount: NaN
in compartment: meta cell
name: TPI1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#c4e94511_9dcd_41ab_807f_f11939edf28a
units: dimensionless
value: 10000.0
type: LocalParameter

meta NADH
type: Species
initial concentration: 0.0867096979846952
initial amount: NaN
boundary condition: true
constant: false
is: SBO:0000247
in compartment: meta cell
is: C00004
has only substance units: false
name: NADH
is: CHEBI:16908

meta NAD
is: CHEBI:15846
is: SBO:0000247
initial concentration: 1.50329030201531
name: NAD
type: Species
in compartment: meta cell
constant: false
is: C00003
initial amount: NaN
boundary condition: false
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260004#a80a1ec7_348c_4563_9692_7670b011065c
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_59adc6ee_fc92_40a6_947f_02511005fddc
units: dimensionless
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_4ab8521d_a280_4ffe_b4af_bcf9a382de0d
value: 7500.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_539063d5_e2f0_4be7_aee6_1d919fcbfb4a
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#c89f9279_ffed_4712_af4e_6c2d32b95eb6
value: 1.57816666666667
type: LocalParameter

meta glycogen
is: SBO:0000247
initial amount: NaN
type: Species
name: glycogen
in compartment: meta cell
boundary condition: true
constant: true
is: CHEBI:28087
has only substance units: false
is: C00182
initial concentration: 0.0

http://identifiers.org/biomodels.db/MODEL1303260004#_5d3f39fb_a7e7_42f2_a57c_497c62819501
value: 0.0721
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_8bb554a1_c4a5_48ac_bf2a_5489f5d70727
value: 17.6
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_2b4165a9_7ab8_42bd_8f6f_ec20662c461b
units: dimensionless
value: 5.12
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_1e0f9f06_7a78_403c_a7ff_c802fb8eaa7a
value: 0.04
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_121ae15b_b406_471c_bfa8_8a8a281c3904
value: 1.4
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#ef25abc6_49e5_44cd_8425_cc06d4d80c1b
value: 0.53
type: LocalParameter

meta SUC
in compartment: meta cell
initial amount: NaN
name: succinate
boundary condition: true
type: Species
is: SBO:0000247
is: C00042
has only substance units: false
initial concentration: 0.0
constant: true
is: CHEBI:30031

http://identifiers.org/biomodels.db/MODEL1303260004#_2fc59a12_4e5a_4f77_8e1f_a53e6b67b9f3
units: dimensionless
value: 3.0
type: LocalParameter

meta FBA
is: SBO:0000176
modifier: MODEL1303260004#
is version of: http://identifiers.org/ec-code/4.1.2.13
type: Reaction
is version of: GO:0004332
fast: false
name: fructosebisphosphate aldolase
reversible: true
is: R01068

http://identifiers.org/biomodels.db/MODEL1303260004#_23a648a0_2b38_456d_b254_3d4b0ce7ab7d
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_0927c995_00ee_410d_8179_ca94da4ff7fe
value: 1.5
type: LocalParameter

meta GPM
modifier: MODEL1303260004#
is: SBO:0000176
is: R01518
name: phosphoglyceromutase
type: Reaction
is version of: http://identifiers.org/ec-code/5.4.2.1
is version of: GO:0004619
fast: false
reversible: true

http://identifiers.org/biomodels.db/MODEL1303260004#e0687bff_f2eb_410d_855c_a786d220b42e
value: 19.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#e7b08dea_90fa_49eb_b53d_de61023fb3fd
units: dimensionless
value: 0.045
type: LocalParameter

meta PGI
name: phosphoglucose isomerase
reversible: true
is: R00771
type: Reaction
fast: false
is version of: http://identifiers.org/ec-code/5.3.1.9
is: SBO:0000176
modifier: MODEL1303260004#
is version of: GO:0004347

http://identifiers.org/biomodels.db/MODEL1303260004#_999bc450_393f_48a0_b02d_d1ab2fee1918
value: 0.865
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_47a0c495_7333_46b9_8899_d37e11021b36
stoichiometry: 1.0
species: meta AMP
type: SpeciesReference

meta ATPase
modifier: MODEL1303260004#
name: ATPase
type: Reaction
reversible: false
is: SBO:0000176
is version of: GO:0016887
fast: false

http://identifiers.org/biomodels.db/MODEL1303260004#_8bf2ada8_862b_4724_8235_75bba76824f9
value: 0.23
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#bf8ff302_7f99_4c73_a3d8_2753fbd28c80
units: dimensionless
value: 0.66
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_62dd2521_27f5_46f8_b16e_ef259f809ae3
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

meta glycogen branch
name: glycogen branch
fast: false
modifier: MODEL1303260004#
type: Reaction
is: SBO:0000176
is version of: GO:0005978
reversible: false

http://identifiers.org/biomodels.db/MODEL1303260004#_2b485545_8277_462a_ac25_6a5e266bd5ca
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_79b54171_f49c_4f82_9ecb_8df3b7efd04b
value: 0.031
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#dad17351_a86d_4b46_b836_c980351e074b
stoichiometry: 1.0
species: meta G3P
type: SpeciesReference

meta G6P
constant: false
type: Species
initial amount: NaN
has only substance units: false
boundary condition: false
initial concentration: 0.193120800911304
in compartment: meta cell
is: CHEBI:17665
is: SBO:0000247
is: C00668
name: glucose 6-phosphate

http://identifiers.org/biomodels.db/MODEL1303260004#_6daedcc1_e379_422a_aa5c_eda34e5f5415
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#b5d057d8_dd8e_48b7_b9ab_25332b66e7d7
stoichiometry: 1.0
species: meta P2G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#a3d83eab_0ba2_4924_9ebc_ec7598ad231b
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

meta PDC5
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00308868608169189
initial amount: NaN
in compartment: meta cell
name: PDC5
type: Species

meta F6P
is: CHEBI:16084
name: fructose 6-phosphate
initial concentration: 0.0588603054728053
is: SBO:0000247
boundary condition: false
type: Species
constant: false
has only substance units: false
is: C05345
in compartment: meta cell
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260004#_6aa7046f_8ade_48f8_85c3_34c351d3a279
value: 21.0
type: LocalParameter

meta PFK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0116962574765781
initial amount: NaN
in compartment: meta cell
name: PFK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#_91450e4c_3896_4b5a_984e_0d8ba3aa35a7
constant: true
value: 1.59
type: Parameter

meta TRH
boundary condition: true
initial amount: NaN
name: trehalose
is: SBO:0000247
type: Species
is: C01083
initial concentration: 0.00384697134241316
is: CHEBI:16551
constant: true
has only substance units: false
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260004#b1378454_f084_40f4_8c3f_c84737f275b8
value: 0.54
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_22f618cc_fd03_46fc_84b8_5171ed232c52
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_5a30aa75_b151_43d6_8025_62629c7bd118
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_09742852_a1dc_499e_9f81_adf73a245604
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_499edd54_453c_41ee_b3a8_4599ce38741c
stoichiometry: 1.0
species: meta P3G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_8d097592_b067_4514_9dc6_b5fb78280be3
stoichiometry: 1.0
species: meta F6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_3f47253c_35d3_4606_9412_d8b344a9de28
value: 0.93
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_92fec20b_c524_4ce5_b1c3_d67934559c04
units: dimensionless
value: 0.91
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#a6fe4668_8b15_4ab3_ac2d_fabae84ee70b
stoichiometry: 2.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#d04e63cc_7c5c_4635_b974_3e4fd1dd59a1
units: dimensionless
value: 6.7
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_3d969bcc_b059_4174_a2f8_cfe1af4c5c4f
value: 0.92
type: LocalParameter

meta HXK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0041951864287446
initial amount: NaN
in compartment: meta cell
name: HXK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#ed7da896_c0ca_4cd9_ada7_61d12671a81e
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta F16bP
initial concentration: 1.14580464751733
type: Species
is: C05378
boundary condition: false
in compartment: meta cell
has only substance units: false
initial amount: NaN
constant: false
is: SBO:0000247
is: CHEBI:28013
name: fructose 1,6-bisphosphate

http://identifiers.org/biomodels.db/MODEL1303260004#_7fb6eafe_022a_4b48_99b2_d404e44d9bee
units: dimensionless
value: 0.19
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#c6cbfdf6_5222_4757_8b62_7935aa0dd864
stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_10d50507_806c_48ea_b5dd_a1c1dc29264e
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta PYR
is: C00022
constant: false
is: CHEBI:15361
in compartment: meta cell
initial concentration: 0.527117851793548
has only substance units: false
name: pyruvate
boundary condition: false
type: Species
initial amount: NaN
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1303260004#_092a4247_a19e_4793_8f91_27ff25da7ea7
value: 0.17
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#df082e8d_959f_4972_a20b_362f192f2d67
value: 0.23
type: LocalParameter

meta extracellular
is: GO:0005576
constant: true
size: 1.0
spatial dimensions: 3.0
name: extracellular
type: Compartment

http://identifiers.org/biomodels.db/MODEL1303260004#aaa496cc_4575_48a4_a6b1_26428dd75a31
value: 0.73
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#e3f93060_d331_4491_b04d_09a1e5cd43ef
stoichiometry: 1.0
species: meta G3P
type: SpeciesReference

meta PDC6
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0016352160527653
initial amount: NaN
in compartment: meta cell
name: PDC6
type: Species

meta ADP
name: ADP
initial concentration: 1.29
has only substance units: false
is: SBO:0000247
constant: false
in compartment: meta cell
is: CHEBI:16761
initial amount: NaN
type: Species
is: C00008
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1303260004#c35f3d92_4470_4c85_aa45_99f912cf7a88
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_796c4a07_d254_45f0_8a25_bbd8f875942d
value: 0.003
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#d384c3eb_9076_499d_9d3c_013b5bb580a6
exponent: -1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260004#_7219329a_0e65_44c7_bf8c_56cbb6cbc80f
value: 3.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#b42ef7ff_d5c2_4631_99b9_d6dfcecf4a1f
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta PGK
modifier: MODEL1303260004#
reversible: true
type: Reaction
name: 3-phosphoglycerate kinase
fast: false
is: R01512
is: SBO:0000176
is version of: GO:0004618
is version of: http://identifiers.org/ec-code/2.7.2.3

http://identifiers.org/biomodels.db/MODEL1303260004#_7c1baab6_d3ef_43c4_931d_283e6a3fee01
units: dimensionless
value: 3200.0
type: LocalParameter

meta HXK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0153328384926289
initial amount: NaN
in compartment: meta cell
name: HXK2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#_646f1681_e0b8_419f_a121_1b81b2bb93f3
value: 1.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_7213f48b_2cb0_41c4_9689_4b3db49595c2
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260004#_89677eba_5f41_4885_b9c9_502202c8a6f5
value: 0.65
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_8da2db62_c3dd_4d4d_ba8b_583d9ee46d6f
units: dimensionless
value: 0.397
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#e7abb10c_0e2f_4280_8b7f_a5ad566a7dc3
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_697f6466_1b60_4df3_8408_53d544d96dfa
value: 0.237257345562943
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_93bb1479_0e67_46ef_b0c6_3aa5c6f546b7
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#e5ed78da_a430_4941_833f_5769f008085e
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta GLC
name: glucose
has only substance units: false
is: SBO:0000247
type: Species
initial concentration: 1.5700004483456
is: CHEBI:4167
is: C00031
constant: false
boundary condition: false
in compartment: meta cell
initial amount: NaN

meta TDH1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.087716160700349
initial amount: NaN
in compartment: meta cell
name: TDH1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#_8ef1cdec_a70d_41c0_ac1c_3251f7740004
value: 1.2
type: LocalParameter

meta PDC
reversible: false
type: Reaction
is: R00636
is version of: GO:0004737
fast: false
is version of: http://identifiers.org/ec-code/4.1.1.1
modifier: MODEL1303260004#
is: SBO:0000176
name: pyruvate decarboxylase

http://identifiers.org/biomodels.db/MODEL1303260004#_4859512d_e578_4870_8e62_b496d2b41f26
name: per mM per second
type: SBMLUnitsDef

meta ATP
constant: false
initial concentration: 4.29
is: SBO:0000247
in compartment: meta cell
name: ATP
boundary condition: false
type: Species
is: CHEBI:15422
is: C00002
has only substance units: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260004#be1d536c_c9d4_4c73_9a2f_83d6739f38e5
constant: true
units: dimensionless
value: 2000.0
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260004#_400ca40c_799a_4179_b444_86a4a3130213
units: dimensionless
value: 14492.7536231884
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_85ac64d4_2bf2_43a8_9b0b_66df35335359
stoichiometry: 1.0
species: meta F6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_2b38060e_43a1_4d37_8875_621796a971d7
value: 0.21
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_7ad3e199_5dc5_444e_829b_327e9ce56a87
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260004#e2bd3fda_5a46_4201_ba4c_98b528cf5d7a
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta HXK GLK1
is version of: http://identifiers.org/ec-code/2.7.1.1
is version of: GO:0004396
is: SBO:0000176
reversible: true
fast: false
is: R02848
type: Reaction
modifier: MODEL1303260004#
name: hexokinase [GLK1]

http://identifiers.org/biomodels.db/MODEL1303260004#e459a7cd_9c37_4a6e_8d6c_c5c56cf45952
value: 0.06
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#af620fc1_215c_4957_a6b1_8111b9862446
stoichiometry: 1.0
species: meta F16bP
type: SpeciesReference

meta PFK
reversible: false
is version of: http://identifiers.org/ec-code/2.7.1.11
modifier: MODEL1303260004#
fast: false
type: Reaction
name: phosphofructokinase
is version of: GO:0003872
is: SBO:0000176
is: R00756

http://identifiers.org/biomodels.db/MODEL1303260004#de917c90_6c82_49de_a90d_6f682175ca1d
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#de57cf88_1d21_40bc_9736_856dca99a014
name: mM per second
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260004#_311be363_f646_4a17_a7e4_a20870cec1e9
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#bb64beb0_bd81_4436_884a_f07bfcc9b7a4
value: 0.3
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_4cbf0bdc_487b_43e0_945c_dd441eeaaea3
units: dimensionless
value: 1.9
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_0c58b054_25b1_46b5_80b8_8c4f7caf7a68
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#bb579da8_6145_4645_be27_284fac75db84
constant: true
value: 6.02
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260004#_5c227ea9_4a41_40eb_8608_785200b52a1c
constant: true
value: 6.022140000000001E20
name: Avogadro constant
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260004#_09f3643a_fc73_4037_bd28_e696c46722fc
value: 111.334973497906
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_11732d32_bd74_4d33_a1e5_e5f9f10b3956
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

meta P3G
is: SBO:0000247
has only substance units: false
boundary condition: false
is: C00197
is: CHEBI:17794
initial concentration: 0.117456252783611
constant: false
initial amount: NaN
in compartment: meta cell
name: 3-phosphoglycerate
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#f86407c3_5644_47eb_9111_64a4f14238e4
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_6f818fb7_7ff5_4a31_8115_29c62470c643
stoichiometry: 1.0
species: meta TRH
type: SpeciesReference

meta PDC1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.266952694557084
initial amount: NaN
in compartment: meta cell
name: PDC1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#dfd09480_5f0e_4df1_9451_16f434c2ac30
stoichiometry: 2.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#f38c887f_584d_4a8d_bce6_632e63b19586
value: 0.53
type: LocalParameter

meta P2G
in compartment: meta cell
is: C00631
type: Species
has only substance units: false
boundary condition: false
initial concentration: 0.0169344770274836
is: SBO:0000247
is: CHEBI:17835
constant: false
name: 2-phosphoglycerate
initial amount: NaN

meta DHAP
name: dihydroxyacetone phosphate
is: C00111
is: CHEBI:16108
type: Species
boundary condition: false
in compartment: meta cell
initial amount: NaN
constant: false
has only substance units: false
is: SBO:0000247
initial concentration: 0.290344213186674

http://identifiers.org/biomodels.db/MODEL1303260004#_75c338d0_5bf4_479e_b263_5ca2e103328b
value: 0.783333333333333
type: LocalParameter

meta succinate branch
modifier: MODEL1303260004#
type: Reaction
is version of: GO:0006105
fast: false
name: succinate branch
reversible: false
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1303260004#_9d203e18_8d83_4a47_a469_77d1a6681fee
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#af32276f_7189_433b_877c_34240d8b37ab
name: per second
type: SBMLUnitsDef

meta G3P
constant: false
has only substance units: false
is: C00093
is: SBO:0000247
is: CHEBI:15978
name: glycerol 3-phosphate
type: Species
in compartment: meta cell
initial amount: NaN
boundary condition: false
initial concentration: 0.068500732297821

http://identifiers.org/biomodels.db/MODEL1303260004#_3537ba13_fbeb_4a96_8ff6_f634003ddef1
constant: true
units: litre
value: 2.0E-14
name: volume
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260004#_9201d8cc_96d3_45f0_becc_6f2d8ed08ed7
value: 0.9
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_6bdecce5_5af1_4289_ab59_744dea5d5d0e
value: 2.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_22f3b67e_ac5f_4fa1_8f0d_d7a31c36d53e
value: 0.023
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_105d589d_e381_42f5_ab4a_8ceaaa9bfd5f
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#b848f2bf_0017_4a66_9f17_8bd3195fa708
value: 3.35
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_058c1502_70a7_4fb0_a70d_a686e8096610
name: mmol
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260004#f65b7629_9284_4bad_ab97_a00ead911227
stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_27783419_640f_4549_b6eb_547c5d80b626
units: dimensionless
value: 0.00533412710224736
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#e0c0875f_8204_4dfd_a869_97590ce778bd
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta F26bP
boundary condition: true
is: C00665
name: fructose 2,6-bisphosphate
has only substance units: false
initial concentration: 0.003
in compartment: meta cell
is: CHEBI:28602
type: Species
constant: true
initial amount: NaN
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1303260004#_3a33e132_062e_4e36_bd3b_cadd910606d4
value: 0.069
type: LocalParameter

meta trehalose branch
reversible: false
name: trehalose branch
is version of: GO:0005992
is: SBO:0000176
fast: false
type: Reaction
modifier: MODEL1303260004#

http://identifiers.org/biomodels.db/MODEL1303260004#_99f0d098_2f40_4fdd_a85e_abec7d6ff844
exponent: -1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260004#a3269ec4_e0d1_4472_a9cf_1eaf7082b07d
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260004#c8f7bed7_429d_4560_809f_34ff976561a0
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_59988bad_a3b7_4df8_8cd9_c1da2dd47a49
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260004#_45ed4e3b_e869_48b9_b6ee_d1a0d4e96042
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#f5251176_d6f6_4e3f_bbee_a814e0660755
value: 0.71
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#e8d159ef_c9bc_4f77_8f52_b3fef06cc57e
units: dimensionless
value: 0.45
type: LocalParameter

meta HXT
modifier: MODEL1303260004#
reversible: true
name: glucose transport
type: Reaction
fast: false
is: SBO:0000185
is version of: GO:0015758

meta TDH
type: Reaction
name: glyceraldehyde phosphate dehydrogenase
is: R01061
is version of: http://identifiers.org/ec-code/1.2.1.12
is version of: GO:0004365
is: SBO:0000176
reversible: true
fast: false
modifier: MODEL1303260004#

meta ADH5
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00106249605621922
initial amount: NaN
in compartment: meta cell
name: ADH5
type: Species

meta GLY
type: Species
name: glycerol
is: SBO:0000247
initial concentration: 0.15
initial amount: NaN
has only substance units: false
boundary condition: true
is: C00116
constant: true
in compartment: meta cell
is: CHEBI:17754

meta ENO2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.493611573294543
initial amount: NaN
in compartment: meta cell
name: ENO2
type: Species

meta GPM1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.182500074724267
initial amount: NaN
in compartment: meta cell
name: GPM1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#ba913771_7799_477a_890f_cd6f3acaa7c0
value: 0.09
type: LocalParameter

meta ENO
name: enolase
is: SBO:0000176
is version of: GO:0004634
modifier: MODEL1303260004#
type: Reaction
is version of: http://identifiers.org/ec-code/4.2.1.11
is: R00658
reversible: true
fast: false

http://identifiers.org/biomodels.db/MODEL1303260004#_4cf179e8_1fc7_49be_90ee_afce7489cece
constant: false
value: NaN
name: glycerate phosphates
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260004#_3fc5fe74_7209_486b_9e68_5e68e4d16c94
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#faeff2c4_7871_4420_b5d6_f7a025b016a6
value: 3.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#ca9f821c_9651_459f_a50c_0be5406d8ac3
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_888e451e_eede_4c91_a126_5de9efda8ad4
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_4e0f7f97_f14f_4397_bdea_d83b3dc3e1e7
value: 43.0833333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#f3150449_d2f5_45fa_809b_d99a6288fd29
value: 1.83333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#e44c530a_407e_4a6f_a3ee_3dfadb97a478
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_39d6dc8a_c40b_42ad_b096_672ad62721bf
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#afc6b0a0_e686_425a_92f1_f9644e502926
stoichiometry: 1.0
species: meta EtOH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_0a3c790e_9ab7_473b_ad9a_ac6f1c2108fe
value: 0.0098
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_32f1d9fb_5ca7_486d_95a3_4bbd7604db93
name: mM
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260004#f0b887fb_e378_4428_92c7_b29d13ee9ff3
value: 1.13333333333333
type: LocalParameter

meta GPD
is: SBO:0000176
fast: false
reversible: true
is: R00842
modifier: MODEL1303260004#
type: Reaction
is: http://identifiers.org/ec-code/1.1.1.94
name: glycerol 3-phosphate dehydrogenase

http://identifiers.org/biomodels.db/MODEL1303260004#e12efe25_8a04_4f90_8398_df7af2bb089b
stoichiometry: 1.0
species: meta P3G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_20527070_a4bb_4212_8db2_33ea98439e55
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_62de6453_7152_4b6c_bd20_3bd1389b1653
name: per mmol
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260004#e17d19c6_0785_422e_a47e_f1d4dd37733e
value: 30.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#d87accaf_4e4d_48cf_8eae_c716ebb4af72
value: 0.00592169973725601
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_9f308b6b_adb9_4f48_ba4b_6fc9a13e3c74
value: 0.2
type: LocalParameter

meta PYK
fast: false
reversible: true
modifier: MODEL1303260004#
type: Reaction
name: pyruvate kinase
is: SBO:0000176
is: R00200
is version of: GO:0004743
is version of: http://identifiers.org/ec-code/2.7.1.40

meta ENO1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.171592988538958
initial amount: NaN
in compartment: meta cell
name: ENO1
type: Species

meta AK
is: SBO:0000176
is version of: GO:0004017
reversible: true
type: Reaction
name: adenylate kinase
modifier: MODEL1303260004#
is version of: http://identifiers.org/ec-code/2.7.4.3
fast: false
is: R00127

http://identifiers.org/biomodels.db/MODEL1303260004#_6c8728f1_0bb9_4969_89e5_e54943c148f2
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#a8c2eef8_05d4_488c_b409_3153c0c6a90d
value: 14.2966666666667
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#e825de8a_f4fd_4bff_8401_fcc810345f46
value: 0.883333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#ee67d63b_9889_4589_a028_16dd509e44c5
value: 6.82E-4
type: LocalParameter

meta PEP
is: C00074
type: Species
is: SBO:0000247
initial amount: NaN
has only substance units: false
name: phosphoenolpyruvate
is: CHEBI:18021
in compartment: meta cell
constant: false
boundary condition: false
initial concentration: 0.152501353339511

meta TPI
is: R01015
is: SBO:0000176
name: triosephosphate isomerase
modifier: MODEL1303260004#
fast: false
is version of: GO:0004807
type: Reaction
reversible: true
is version of: http://identifiers.org/ec-code/5.3.1.1

http://identifiers.org/biomodels.db/MODEL1303260004#_6d48f111_6073_4f6d_ae0d_5c4f9175fe01
units: dimensionless
value: 800.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#e1ba41a9_b28f_4044_8716_49c41e4f238a
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta HXK HXK2
name: hexokinase [HXK2]
is version of: GO:0004396
type: Reaction
is: R02848
fast: false
modifier: MODEL1303260004#
is version of: http://identifiers.org/ec-code/2.7.1.1
reversible: true
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1303260004#ec95eb32_c2a5_42ce_82d0_731d4ede24d7
value: 4.8
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_25fd4a19_44f6_4858_b4e0_542d0192e95d
value: 4.33
type: LocalParameter

W3 CDTF: Sun Nov 09 00:00:00 GMT 2008

http://identifiers.org/biomodels.db/MODEL1303260004#_3039f956_7880_4153_add0_93b2171d0cfa
value: 0.01480424934314
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#d2adafbf_c42c_4374_835d_5233040b46ed
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_799386bd_1539_43e8_82e5_57ed24fc895e
value: 90.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_72ae0b4b_1b72_4e7f_a343_ec1b523db899
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_17ad46d8_2c5f_46af_a422_236de2838f98
value: 1.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_96facc7b_c01d_4c7e_a64f_fa186988d92d
value: 17.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_3f8c714c_4e67_4056_8a35_f75d4cc23109
value: 0.195
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#f7c1869c_26b9_461d_ba5f_a0e2c2205c0c
stoichiometry: 1.0
species: meta P2G
type: SpeciesReference

meta ADH
modifier: MODEL1303260004#
type: Reaction
name: alcohol dehydrogenase
fast: false
is version of: http://identifiers.org/ec-code/1.1.1.1
is version of: GO:0004022
reversible: true
is: R00754
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1303260004#_0bdd5520_1f5a_44d1_b52d_c38a32a12c1f
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#a57ae4b3_62ff_4ac3_a576_2e7299d57eef
stoichiometry: 1.0
species: meta SUC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_278cad0d_0d17_4076_ae7c_0a7239c09ff8
value: 1.11
type: LocalParameter

meta EtOH
is: CHEBI:16236
initial amount: NaN
name: ethanol
is: C00469
initial concentration: 55.472577854384
in compartment: meta cell
constant: true
has only substance units: false
type: Species
boundary condition: true
is: SBO:0000247

meta TDH3
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.05110118662137
initial amount: NaN
in compartment: meta cell
name: TDH3
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#_1a7d291f_6297_4492_8d08_697101563917
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta HXK HXK1
is version of: http://identifiers.org/ec-code/2.7.1.1
reversible: true
is: SBO:0000176
fast: false
modifier: MODEL1303260004#
name: hexokinase [HXK1]
is version of: GO:0004396
type: Reaction
is: R02848

http://identifiers.org/biomodels.db/MODEL1303260004#d5a8895c_e2b9_4a68_9884_55d23df7e5aa
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#e510601f_ebc2_441c_a3ad_bd546cac30df
stoichiometry: 1.0
species: meta GLY
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_7d512f1a_a562_4c7a_8a10_4422130d1a1a
value: 2.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#e7261f46_292c_43f1_9bf4_f9c9aaf709e2
value: 10.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_32842944_b920_45a1_921d_2c2ac0fff281
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta GLCx
is: SBO:0000247
boundary condition: true
has only substance units: false
name: glucose
is: C00031
initial concentration: 74.0
type: Species
in compartment: meta extracellular
is: CHEBI:4167
constant: true
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260004#_2dcbfab3_6de8_4e87_86b4_bdd294574232
value: 0.23
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_0069bfe3_00ef_488f_a6c2_6f32e447416b
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_8a4987b2_e4fc_41e5_93b3_2b97d74bbca6
value: 0.75
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_31fb1221_a072_4f83_bdae_7ab7a4427720
stoichiometry: 1.0
species: meta glycogen
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#e4416f56_c8ff_4b1a_af6a_d2dfff6b8139
value: 30.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#ff1c7159_f1bf_4eb9_b1c6_15b6579c1b50
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

meta AMP
name: AMP
is: C00020
has only substance units: false
is: CHEBI:16027
is: SBO:0000247
in compartment: meta cell
type: Species
boundary condition: true
initial concentration: 0.44
constant: false
initial amount: NaN

meta HOR2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0013683673909939
initial amount: NaN
in compartment: meta cell
name: HOR2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#_0161fac1_65b0_4dc6_9e30_b64909be0792
value: 259.220125786164
type: LocalParameter

meta TDH2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: meta cell
name: TDH2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#a553345a_d209_4d57_b966_2650af575825
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

meta ADH1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0409771277320022
initial amount: NaN
in compartment: meta cell
name: ADH1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#ed0ba7ad_9b14_4337_ab72_e1a6ed760cbc
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_2622cd56_4d3b_4094_8a44_84eab09699e8
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_78d68a70_7eff_4fd0_bd73_68fceefd8778
stoichiometry: 1.0
species: meta GLCx
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_24965355_5575_4279_a5e3_e25aa9100774
value: 0.11
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_4053dd61_ec99_4282_aa14_c0a0d3963977
units: dimensionless
value: 0.0845
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#a13fdd82_98eb_4488_97a6_7823a128ebeb
value: 16.6666666666667
type: LocalParameter

meta GAP
is: CHEBI:29052
constant: false
has only substance units: false
boundary condition: false
is: C00118
name: glyceraldehyde 3-phosphate
type: Species
initial amount: NaN
in compartment: meta cell
is: SBO:0000247
initial concentration: 0.0789727571926259

meta CDC19
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.512097526792801
initial amount: NaN
in compartment: meta cell
name: CDC19
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#eec315c3_2a8f_4cf6_b0f0_ef71e4570f93
units: dimensionless
value: 6500.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_5d53267d_4109_4850_a3c3_9454bfe6dc07
value: 0.14
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_93b14f02_1c21_49ec_8392_9af9855d193c
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260004#_542e212b_2c0b_4cbd_bfd7_d34356fa6e7a
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260004#f7420399_aa0a_43b3_97cf_ab7e699546d9
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_06f74e81_b8fe_4e57_9fce_be150379b6fe
value: 0.08
type: LocalParameter

meta FBA1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0367018202831552
initial amount: NaN
in compartment: meta cell
name: FBA1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#_4e385881_2cd2_431c_905a_d82a5c2fd09b
value: 0.0106
type: LocalParameter

meta GLK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0112717406104807
initial amount: NaN
in compartment: meta cell
name: GLK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#_38e7b91a_21f2_4b95_b3e5_183badd937e0
value: 63.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_050a904f_e008_494c_bf57_444f3e8a3e44
value: 2.4
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_0c48791d_d180_46a0_9105_30a0005912da
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_4b0425ba_1e87_41e1_91cd_291aec7cf5c9
stoichiometry: 1.0
species: meta F16bP
type: SpeciesReference

meta PYK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00151748381804475
initial amount: NaN
in compartment: meta cell
name: PYK2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#_9100d10a_14a0_4c5d_9924_367639f62cfd
stoichiometry: 2.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#cae41843_c35d_48d3_94ce_20679df76a62
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_1b5fc502_ec84_4838_ac5e_d6b407b0b1c0
stoichiometry: 3.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#a6fed363_48eb_4a2c_97cc_64cb56669214
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260004#aa07b1c6_0c24_4af4_bb63_b1f303ece6cc
value: 0.293
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#f72a9ae8_ce57_4b39_ada5_83423d1445f7
value: 0.3
type: LocalParameter

meta PFK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00975915538330228
initial amount: NaN
in compartment: meta cell
name: PFK2
type: Species

meta AcAld
has only substance units: false
type: Species
in compartment: meta cell
is: CHEBI:15343
initial amount: NaN
is: SBO:0000247
is: C00084
boundary condition: false
initial concentration: 0.178140579850657
constant: false
name: acetaldehyde

http://identifiers.org/biomodels.db/MODEL1303260004#_3aabe2c7_b034_4406_9cf9_7a9fa23b26ed
value: 0.3
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#b2f7ac62_00a4_48d6_9bcf_61f975eb5268
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_432a8451_d081_4313_83d0_aebeef84aaea
units: dimensionless
value: 0.0174
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_820d5d41_42ff_49c7_ade5_fb2706459979
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260004#_51f91bed_9e93_444c_b2c3_5af012ab3edc
units: dimensionless
value: 0.29
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_395fe538_662f_41f8_8b8d_608fa192ce9d
value: 3.36
type: LocalParameter

meta GPD2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.98351416606057E-4
initial amount: NaN
in compartment: meta cell
name: GPD2
type: Species

meta cell
is: GO:0005829
constant: true
size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

meta RHR2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0127951193429578
initial amount: NaN
in compartment: meta cell
name: RHR2
type: Species

meta PGK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0644142281647388
initial amount: NaN
in compartment: meta cell
name: PGK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260004#acf38745_9e09_4dd0_9369_9d1b55e802ec
value: 0.0995
type: LocalParameter

meta BPG
name: 1,3-bisphosphoglycerate
in compartment: meta cell
type: Species
has only substance units: false
boundary condition: false
is: CHEBI:16001
constant: false
initial concentration: 7.36873499865602E-4
is: C00236
initial amount: NaN
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1303260004#e4d1bf7b_807f_49f2_8a8a_3c1b681938d7
value: 30.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_65aa5920_4692_4194_ac67_f06a69a9f72f
value: 0.111
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260004#_102950a6_2c34_4991_92df_5a97f52a92c7
constant: false
units: dimensionless
value: NaN
type: Parameter

meta GPP
is: http://identifiers.org/ec-code/3.1.3.21
reversible: false
fast: false
type: Reaction
modifier: MODEL1303260004#
is: R00841
is: SBO:0000176
name: glycerol 3-phosphatase

http://identifiers.org/biomodels.db/MODEL1303260004#df669894_257c_4b09_a450_82d560f83755
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

meta GPD1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00170877794272468
initial amount: NaN
in compartment: meta cell
name: GPD1
type: Species

meta PGI1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0345726768225249
initial amount: NaN
in compartment: meta cell
name: PGI1
type: Species

MODEL1303260004
name: max
species: meta FBA1
species: meta PFK2
name: reversible michaelis-menten: two noncompeting couples
reaction: meta HXK HXK2
compartment: meta extracellular
species: meta P2G
reaction: meta TDH
reaction: meta AK
reaction: meta ENO
species: meta PDC6
name: irreversible michaelis-menten: one substrate, no product
species: meta ADH1
species: meta GAP
area units: area
reaction: meta PGI
notes: Smallbone2013 - Glycolysis in S.cerevisiae - Iteration 04 This model is described in the article: A model of yeast glycolysis based on a consistent kinetic characterization of all its enzymes Kieran Smallbone, Hanan L. Messiha, Kathleen M. Carroll, Catherine L. Winder, Naglis Malys, Warwick B. Dunn, Ettore Murabito, Neil Swainston, Joseph O. Dada, Farid Khan, Pınar Pir, Evangelos Simeonidis, Irena Spasić, Jill Wishart, Dieter Weichart, Neil W. Hayes, Daniel Jameson, David S. Broomhead, Stephen G. Oliver, Simon J. Gaskell, John E.G. McCarthy, Norman W. Paton, Hans V. Westerhoff, Douglas B. Kell, Pedro Mendes FEBS Letters (in press) Abstract: We present an experimental and computational pipeline for the generation of kinetic models of metabolism, and demonstrate its application to glycolysis in Saccharomyces cerevisiae. Starting from an approximate mathematical model, we employ a “cycle of knowledge” strategy, identifying the steps with most control over flux. Kinetic parameters of the individual isoenzymes within these steps are measured experimentally under a standardised set of conditions. Experimental strategies are applied to establish a set of in vivo concentrations for isoenzymes and metabolites. The data are integrated into a mathematical model that is used to predict a new set of metabolite concentrations and reevaluate the control properties of the system. This bottom-up modelling study reveals that control over the metabolic network most directly involved in yeast glycolysis is more widely distributed than previously thought. This model is hosted on BioModels Database and identified by: MODEL1303260004 . To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models . To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more …
reaction: meta FBA
reaction: meta TPI
reaction: meta PDC
reaction: meta glycogen branch
species: meta PEP
species: meta HXK1
reaction: meta ATPase
species: meta PYK2
species: meta G6P
species: meta glycogen
species: meta NAD
reaction: meta GPM
species: meta GLC
name: Hill kinetics
species: meta SUC
species: meta GPD1
species: meta PGK1
species: meta PGI1
reaction: meta HXK HXK1
species: meta HOR2
reaction: meta GPP
species: meta RHR2
species: meta F16bP
name: reversible michaelis-menten: ordered uni-bi
name: phosphofructokinase kinetics with Keq
type: SBMLModel
reaction: meta GPD
name: irreversible mass action
species: meta TRH
species: meta F6P
species: meta PDC1
reaction: meta PGK
species: meta F26bP
species: meta GLY
species: meta NADH
reaction: meta HXK GLK1
species: meta P3G
species: meta ADP
name: reversible michaelis-menten: one substrate, one product
curated: false
species: meta PYR
species: meta DHAP
species: meta ATP
reaction: meta succinate branch
reaction: meta trehalose branch
compartment: meta cell
species: meta ADH5
species: meta TDH2
species: meta HXK2
species: meta GPM1
species: meta ENO2
species: meta EtOH
species: meta TPI1
initial assignment: MODEL1303260004#
species: meta AMP
name: reversible michaelis-menten: two substrates, two products, three inhibitors, non-competitive inhibition
reaction: meta ADH
species: meta BPG
species: meta GPD2
name: reversible michaelis-menten: ordered bi-bi
species: meta AcAld
reaction: meta PYK
species: meta G3P

W3 CDTF: Wed Nov 14 14:34:50 GMT 2012

given: Kieran
family: Smallbone

orgname: University of Manchester