1-phosphatidyl-1D-myo-inositol 4-phosphate [vacuole]
(S)-3-hydroxytetradecanoyl-CoA [endoplasmic reticulum]
COX1:COX12:COX13:COX2:COX3:COX4:COX5A:COX6:COX7:COX8:COX9:CYC7 [mitochondrial membrane]
purine-nucleoside phosphorylase (adenosine)
Delta(6)-trans,Delta(8)-cis-leukotriene B4 [cytoplasm]
GENE_ASSOCIATION:(YER070W or YJL026W or YIL066C or YGR180C or (YER070W and YJL026W) or (YER070W and YGR180C) or (YER070W and YJL026W) or (YGR180C and YIL066C))
aldehyde dehydrogenase (acetaldehyde, NADP)
alcohol acetyltransferase (phenylethanol alcohol)
LAT1:LPD1:PDA1:PDB1:PDX1 [mitochondrion]
5'-phosphoribosyl-N-formylglycineamide [cytoplasm]
phosphatidylinositol 3,5-bisphosphate phosphatase
(2S)-2-isopropyl-3-oxosuccinate(2-) [mitochondrion]
ceramide-2 (C26) [endoplasmic reticulum]
phosphoribosyl-carboxy-aminoimidazole [cytoplasm]
3-methyl-2-oxobutanoate hydroxymethyltransferase
GENE_ASSOCIATION:(YAL044C and YDR019C and YFL018C and YMR189W)
3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase
GENE_ASSOCIATION:((YCL035C and YPL091W) or (YDR098C and YPL091W) or (YDR513W and YPL091W) or (YER174C and YPL091W))
sn-glycero-3-phosphocholine [endoplasmic reticulum]
GENE_ASSOCIATION:(YBR126C and YDR074W and (YML100W or YMR261C))
alpha,alpha-trehalose-phosphate synthase (UDP-forming)
1-phosphatidyl-1D-myo-inositol 3-phosphate [vacuole]
GENE_ASSOCIATION:((YGL205W and YIL160C and YKR009C and YLR284C and YNL202W) or (YGL205W and YIL160C and YKR009C and YLR284C and YNL202W and YOR180C) or (YGL205W and YIL160C and YKR009C and YNL202W and YOR180C))
1D-myo-inositol 4,5-bisphosphate:SLM1 [cytoplasm]
1-phosphatidyl-1D-myo-inositol [vacuole]
GENE_ASSOCIATION:((YGR175C and YIL043C and YNL111C) or (YGR175C and YKL150W and YNL111C))
phosphatidylinositol phosphate phosphatase
N-(5-phospho-beta-D-ribosyl)anthranilate [cytoplasm]
3'-phospho-5'-adenylyl sulfate [cytoplasm]
hexadecaprenyl diphosphate [lipid particle]
myo-inositol 1,3,4,5,6-pentakisphosphate [cytoplasm]
tridecaprenyl diphosphate [lipid particle]
dodecaprenyl diphosphate [lipid particle]
1-acylglycerophosphocholine [mitochondrion]
5-formyltetrahydrofolic acid [cytoplasm]
GENE_ASSOCIATION:(YER056C or YER060W or YER060W-A or YGL186C)
dihydroxyacetone phosphate [mitochondrion]
3-phosphoshikimate 1-carboxyvinyltransferase
3-ketosphinganine [endoplasmic reticulum]
mannosylinositol phosphorylceramide A (C24) [endoplasmic reticulum]
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase
GENE_ASSOCIATION:(YGR037C and YKL182W and YNR016C and YPL231W)
5-methylthio-5-deoxy-D-ribulose 1-phosphate dehydratase
4-hydroxy-2-oxoglutarate(2-) [mitochondrion]
glutamine-fructose-6-phosphate transaminase
nicotinic acid D-ribonucleotide [mitochondrion]
5-methylthioribose-1-phosphate isomerase
inositol phosphomannosylinositol phosphoceramide D (C24) [Golgi]
S-methyl-5-thio-alpha-D-ribose 1-phosphate [cytoplasm]
glycerol-3-phosphate/dihydroxyacetone phosphate acyltransferase
6-(alpha-D-glucosaminyl)-O-acyl-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
GENE_ASSOCIATION:(YDL245C or YDR342C or YDR343C or YDR345C or YEL069C or YFL011W or YHR092C or YHR094C or YHR096C or YJL214W or YJL219W or YJR158W or YMR011W or YNR072W or YOL156W)
pentaprenyl diphosphate [lipid particle]
Delta(6)-trans,Delta(8)-cis-leukotriene B4 [nucleus]
COX1:COX12:COX13:COX2:COX3:COX4:COX5B:COX6:COX7:COX8:COX9:CYC1 [mitochondrial membrane]
GENE_ASSOCIATION:(YBR026C and YER061C and YHR067W and YKL055C and YKL192C and YOR221C)
trans-4-hydroxy-L-proline [mitochondrion]
GENE_ASSOCIATION:(YAL044C and YBR221C and YDR019C and YER178W and YMR189W)
phosphoribosylaminoimidazolecarboxamide formyltransferase
2-hexaprenyl-6-methoxy-3-methyl-1,4-benzoquinone [mitochondrion]
1-acylglycerophosphocholine [extracellular]
2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase
1-phosphatidyl-1D-myo-inositol 4-phosphate [nucleus]
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid [mitochondrion]
GENE_ASSOCIATION:(YFL001W or YGL063W or YNL292W or YPL212C)
GENE_ASSOCIATION:(YBR145W or YDL168W or YGL256W or YMR303C or YOL086C)
aldehyde dehydrogenase (2-methylbutanol, NAD)
GENE_ASSOCIATION:(YLL028W or YGR138C or YPR156C or YOR273C)
tetracosanoyl-CoA [endoplasmic reticulum]
GENE_ASSOCIATION:((YEL039C and YKR066C) or (YJR048W and YKR066C))
ferrocytochrome-c:hydrogen-peroxide oxidoreductase
pyruvate decarboxylase (acetoin-forming)
GENE_ASSOCIATION:(YGR087C or YLR044C or YLR134W)
5'-phosphoribosyl-N-formylglycineamidine [cytoplasm]
ketol-acid reductoisomerase (2-aceto-2-hydroxybutanoate)
GENE_ASSOCIATION:(YJR051W or (YDR178W and YJL045W and YKL141W and YLL041C) or (YDR178W and YKL141W and YKL148C and YLL041C))
alpha-D-glucosamine 1-phosphate [cytoplasm]
nicotinate-nucleotide diphosphorylase (carboxylating)
GENE_ASSOCIATION:(YLR237W or YOR071C or YOR192C)
inositol-P-ceramide A (C24) [mitochondrion]
1D-myo-inositol 4,5-bisphosphate:SLM2 [cytoplasm]
1-phosphatidyl-1D-myo-inositol [nucleus]
methylenetetrahydrofolate dehydrogenase (NAD)
inositol-1,3,4,5-triphosphate 6-kinase, nucleus
Heavner2012 - Metabolic Network of S.cerevisiae
Heavner2012 - Metabolic Network of S.cerevisiae This SBML representation of the yeast metabolic network is made available under the Creative Commons Attribution-Share Alike 3.0 Unported Licence (see www.creativecommons.org). This model is described in the article: Yeast 5 - an expanded reconstruction of the Saccharomyces cerevisiae metabolic network. Heavner BD, Smallbone K, Barker B, Mendes P, Walker LP. BMC Syst Biol. 2012 Jun 4;6:55. Abstract: BACKGROUND: Efforts to improve the computational reconstruction of the Saccharomyces cerevisiae biochemical reaction network and to refine the stoichiometrically constrained metabolic models that can be derived from such a reconstruction have continued since the first stoichiometrically constrained yeast genome scale metabolic model was published in 2003. Continuing this ongoing process, we have constructed an update to the Yeast Consensus Reconstruction, Yeast 5. The Yeast Consensus Reconstruction is a product of efforts to forge a community-based reconstruction emphasizing standards compliance and biochemical accuracy via evidence-based selection of reactions. It draws upon models published by a variety of independent research groups as well as information obtained from biochemical databases and primary literature. RESULTS: Yeast 5 refines the biochemical reactions included in the reconstruction, particularly reactions involved in sphingolipid metabolism; updates gene-reaction annotations; and emphasizes the distinction between reconstruction and stoichiometrically constrained model. Although it was not a primary goal, this update also improves the accuracy of model prediction of viability and auxotrophy phenotypes and increases the number of epistatic interactions. This update maintains an emphasis on standards compliance, unambiguous metabolite naming, and computer-readable annotations available through a structured document format. Additionally, we have developed MATLAB scripts to evaluate the model's predictive accuracy and to demonstrate basic model applications such as simulating aerobic and anaerobic growth. These scripts, which provide an independent tool for evaluating the performance of various stoichiometrically constrained yeast metabolic models using flux balance analysis, are included as Additional files 1, 2 and 3. CONCLUSIONS: Yeast 5 expands and refines the computational reconstruction of yeast metabolism and improves the predictive accuracy of a stoichiometrically constrained yeast metabolic model. It differs from previous reconstructions and models by emphasizing the distinction between the yeast metabolic reconstruction and the stoichiometrically constrained model, and makes both available as Additional file 4 and Additional file 5 and at http://yeast.sf.net/ as separate systems biology markup language (SBML) files. Through this separation, we intend to make the modeling process more accessible, explicit, transparent, and reproducible. This model is hosted on BioModels Database and identified by: MODEL1209060000 . To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. PMID: 20587024 . To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to [CC0 Public Domain Dedication>http://creativecommons.org/publicdomain/zero/1.0/] for more information.
myo-inositol 1,3,4,5,6-pentakisphosphate [nucleus]
GENE_ASSOCIATION:(YDL042C or YDR191W or YOL068C or YOR025W or YPL015C)
GENE_ASSOCIATION:((Q0105 and YBL045C and YDR529C and YEL024W and YEL039C and YFR033C and YGR183C and YHR001W-A and YJL166W and YOR065W and YPR191W) or (Q0105 and YBL045C and YDR529C and YEL024W and YFR033C and YGR183C and YHR001W-A and YJL166W and YJR048W and YOR065W and YPR191W))
fecosteryl palmitoleate [endoplasmic reticulum]
mannosylinositol phosphorylceramide C (C26) [Golgi]
4-amino-5-hydroxymethyl-2-methylpyrimidine [cytoplasm]
5-diphospho-1D-myo-inositol pentakisphosphate [cytoplasm]
glycine-cleavage complex (lipoylprotein)
1D-myo-inositol 1-phosphate [endoplasmic reticulum]
GENE_ASSOCIATION:(YBR068C or YCL025C or YDR046C or YDR508C or YGR055W or YHL036W or YKR039W)
S-adenosyl-L-homocysteine [endoplasmic reticulum]
mannosylinositol phosphorylceramide A (C24) [Golgi]
ribonucleoside-triphosphate reductase (ATP)
aldehyde dehydrogenase (tryptophol, NAD)
GENE_ASSOCIATION:(YGL205W and YIL160C and YKR009C)
fatty acid oxidation (tetradecansoyl-CoA)
inositol phosphomannosylinositol phosphoceramide D (C24) [endoplasmic reticulum]
GENE_ASSOCIATION:((YGL205W and YIL160C and YKR009C and YLR284C) or (YGL205W and YIL160C and YKR009C and YOR180C))
nicotinic acid D-ribonucleotide [cytoplasm]
phosphatidyl-N,N-dimethylethanolamine [mitochondrion]
S-methyl-5-thio-D-ribulose 1-phosphate [cytoplasm]
octadecaprenyl diphosphate [lipid particle]
GENE_ASSOCIATION:(YDR353W or (YDR353W and YGR209C) or (YDR353W and YLR043C))
GENE_ASSOCIATION:(YBR068C or YBR069C or YCL025C or YDR046C or YKR039W)
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
5'-S-methyl-5'-thioadenosine [cytoplasm]
spontaneous cis-aconitate(3-) to trans-aconitate
5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide [cytoplasm]
sedoheptulose 1,7-bisphosphate D-glyceraldehyde-3-phosphate-lyase
inositol phosphomannosylinositol phosphoceramide B (C26) [mitochondrion]
2-hexaprenyl-6-methoxy-1,4-benzoquinone [mitochondrion]
1-acylglycerophosphocholine [cell envelope]
acetyl-CoA acyltransferase (tetradecanoyl-CoA)
GENE_ASSOCIATION:(YCR020C-A and YEL053C and YPR051W)
(S)-3-methyl-2-oxopentanoate [cytoplasm]
C-3 sterol dehydrogenase (4-methylzymosterol)
GENE_ASSOCIATION:(YDR148C and YFL018C and YIL125W)
oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase)
inositol-P-ceramide B' (C24) [endoplasmic reticulum]
protein with N-terminal(Met-Phe) [cytoplasm]
2-deoxy-D-arabino-heptulosonate 7-phosphate synthetase
aldehyde dehydrogenase (indole-3-acetaldehyde, NADP)
GENE_ASSOCIATION:(YKR089C or YMR313C or YOR081C)
1D-myo-inositol 4,5-bisphosphate:AVO1:AVO2:BIT61:LST8:SLM1:TOR2:TSC11 [cell envelope]
palmitoleoyl-CoA [endoplasmic reticulum]
GPI-anchor assembly, step 11, deacylation reaction as part of glycosylation
lanosteryl oleate [endoplasmic reticulum]
inositol-P-ceramide A (C26) [endoplasmic reticulum]
sphingoid base-phosphate phosphatase (phytosphingosine 1-phosphate)
4-hydroxy-2-oxoglutarate(2-) [cytoplasm]
GENE_ASSOCIATION:(YIL009W or YMR246W or YOR317W)
P(1),P(4)-bis(5'-guanosyl) tetraphosphate [cytoplasm]
ATP1:ATP14:ATP15:ATP16:ATP17:ATP18:ATP2:ATP20:ATP3:ATP4:ATP5:ATP6:ATP7:ATP8:OLI1 [mitochondrial membrane]
GENE_ASSOCIATION:(YBR132C or YHL016C or YKR039W or YLL028W or YPL274W or YOR273C)
3',5'-cyclic-nucleotide phosphodiesterase
dolichyl D-mannosyl phosphate [endoplasmic reticulum]
dolichyl-phosphate D-mannosyltransferase
S(8)-succinyldihydrolipoamide [mitochondrion]
GENE_ASSOCIATION:((YDR178W and YJL045W and YKL141W and YLL041C) or (YDR178W and YKL141W and YKL148C and YLL041C))
succinate dehydrogenase (FADH2, ubiquinone-6)
mannosylinositol phosphorylceramide B (C26) [mitochondrion]
GENE_ASSOCIATION:(YBR068C or YBR069C or YCL025C or YDR046C or YDR508C or YKR039W or YOL020W)
phosphatidylethanolamine [endoplasmic reticulum]
(Z)-tetradec-7-enoyl-ACP [mitochondrion]
3,4-dihydroxy-2-butanone-4-phosphate synthase
DCI1:ECI1:FOX2:POT1:POX1:SPS19 [peroxisome]
fecosteryl oleate [endoplasmic reticulum]
palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA)
mannosylinositol phosphorylceramide D (C24) [endoplasmic reticulum]
phosphatidylinositol-4-phosphate 5-kinase
1D-myo-inositol 4,5-bisphosphate [cytoplasm]
dehydro-D-arabinono-1,4-lactone [cytoplasm]
asparaginyl-tRNA synthetase, miotchondrial
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [cytoplasm]
dihydroxyacetone phosphate [endoplasmic reticulum]
inositol phosphomannosylinositol phosphoceramide A (C24) [Golgi]
mannosylinositol phosphorylceramide A (C24) [mitochondrion]
5-amino-6-(5-phosphoribitylamino)uracil [cytoplasm]
ceramide-2 (C24) [endoplasmic reticulum]
GENE_ASSOCIATION:((YGL205W and YIL160C and YKR009C and YLR284C and YNL202W) or (YGL205W and YIL160C and YKR009C and YNL202W and YOR180C))
tetradecaprenyl diphosphate [lipid particle]
L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase
protein with N-terminal(Met-Trp) [cytoplasm]
COX1:COX12:COX13:COX2:COX3:COX4:COX5A:COX6:COX7:COX8:COX9:CYC1 [mitochondrial membrane]
glycerol-3-phosphate dehydrogenase (NAD)
2-hexaprenyl-5-hydroxy-6-methoxy-3-methyl-1,4-benzoquinone [mitochondrion]
D-erythrose 4-phosphate(2-) [mitochondrion]
GENE_ASSOCIATION:((YEL039C and YML054C) or (YJR048W and YML054C))
(S)-lactate:ferricytochrome-c 2-oxidoreductase
1-acyl-sn-glycerol 3-phosphate [lipid particle]
(S)-3-hydroxytetradecanoyl-CoA [peroxisome]
alcohol dehydrogenase, reverse rxn (acetaldehyde -> ethanol)
aldehyde dehydrogenase (indole-3-acetaldehyde, NAD)
alcohol acetyltransferase (isoamyl alcohol)
GENE_ASSOCIATION:(YDR400W and YLR017W and YLR209C)
phosphopantothenoylcysteine decarboxylase
1D-myo-inositol 4,5-bisphosphate:AVO1:AVO2:BIT61:LST8:SLM2:TOR2:TSC11 [cell envelope]
sphingolipid long chain base kinase (phytosphingosine)
L-glutamic 5-semialdehyde [mitochondrion]
sn-glycero-3-phosphocholine [extracellular]
P(1),P(4)-bis(5'-adenosyl) tetraphosphate [cytoplasm]
1-acyl-sn-gylcerol-3-phosphate acyltransferase
2,3-diketo-5-methylthio-1-phosphopentane degradation reaction
ergosterol 3-beta-D-glucoside [cytoplasm]
GENE_ASSOCIATION:(YBR293W or YCL069W or YMR088C)
5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase
S-adenosyl-4-methylthio-2-oxobutanoate [cytoplasm]
inositol phosphomannosylinositol phosphoceramide C (C26) [mitochondrion]
N-tetradecanoylglycylpeptide [cytoplasm]
D-sorbitol dehydrogenase (D-fructose producing)
2-oxo-4-methyl-3-carboxypentanoate decarboxylation
mannosylinositol phosphorylceramide C (C26) [mitochondrion]
1D-myo-inositol 3-phosphate [mitochondrion]
L-4-hydroxyglutamate semialdehyde dehydrogenase
5-diphosphoinositol-1,2,3,4,6-pentakisphosphate diphosphohydrolase
dihydroxyacetone phosphate [lipid particle]
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [cell envelope]
aldehyde dehydrogenase (isoamyl alcohol, NADP)
inositol phosphomannosylinositol phosphoceramide A (C24) [mitochondrion]
glycogen vacuolar 'transport' via autophagy
GENE_ASSOCIATION:(YDL245C or YDR342C or YDR343C or YDR345C or YDR536W or YEL069C or YFL011W or YHR092C or YHR094C or YHR096C or YJL214W or YJL219W or YJR158W or YLR081W or YMR011W or YNR072W or YOL156W or YDL247W or YDL247W)
PIB1:phosphatidylinositol 3-phosphate [vacuole]
mannosylinositol phosphorylceramide B' (C24) [Golgi]
1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
N-acetyl-D-glucosamine 6-phosphate [cytoplasm]
Aminoacetone:oxygen oxidoreductase(deaminating)(flavin-containing)
COB:COR1:CYC1:CYT1:QCR10:QCR2:QCR6:QCR7:QCR8:QCR9:RIP1 [mitochondrial membrane]
1-acyl-sn-glycerol 3-phosphate [endoplasmic reticulum]
6,7-dimethyl-8-(1-D-ribityl)lumazine [cytoplasm]
glycerol 3-phosphate [endoplasmic reticulum]
inositol phosphomannosylinositol phosphoceramide B' (C24) [Golgi]
5-(2-hydroxyethyl)-4-methylthiazole [cytoplasm]
diacylglycerol pyrophosphate phosphatase
GENE_ASSOCIATION:(YBR298C or YDL247W or YGR289C or YDL247W)
1-phosphatidyl-1D-myo-inositol 3-phosphate [cell envelope]
2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone [cytoplasm]
4beta-methylzymosterol-4alpha-carboxylic acid [cytoplasm]
4-amino-2-methyl-5-phosphomethylpyrimidine [cytoplasm]
orotidine 5'-(dihydrogen phosphate) [cytoplasm]
phosphatidylcholine [endoplasmic reticulum]
phosphoribosyl amino imidazolesuccinocarbozamide synthetase
GENE_ASSOCIATION:((YBR036C and YPL057C) or (YBR036C and YBR161W))
glycinamide ribonucleotide transformylase
aldehyde dehydrogenase (isoamyl alcohol, NAD)
acetylated protein with terminal(Met-Glu) [cytoplasm]
inositol phosphomannosylinositol phosphoceramide C (C26) [Golgi]
1D-myo-inositol 1,4,5,6-tetrakisphosphate [nucleus]
phosphatidyl-L-serine [endoplasmic reticulum]
inositol-P-ceramide B' (C24) [mitochondrion]
GENE_ASSOCIATION:(YBR299W or YGR287C or YGR292W)
ceramide-2' (C26) [endoplasmic reticulum]
1,2-diacylglycerol 3-diphosphate [cell envelope]
1-phosphatidyl-1D-myo-inositol 4-phosphate [mitochondrion]
inositol-P-ceramide D (C24) [mitochondrion]
phosphatidylethanolamine [mitochondrion]
ATP1:ATP14:ATP15:ATP16:ATP17:ATP18:ATP2:ATP3:ATP4:ATP5:ATP6:ATP7:ATP8:OLI1:TIM11 [mitochondrial membrane]
C-terminal processing of farnesylated proteins I
fatty acyl-CoA synthase (n-C8:0CoA), lumped reaction
dihydroneopterin monophosphate dephosphorylase
citrate to cis-aconitate(3-), cytoplasmic
inositol phosphomannosylinositol phosphoceramide A (C26) [endoplasmic reticulum]
7,8-dihydroneopterin 3'-triphosphate [cytoplasm]
COB:COR1:CYC7:CYT1:QCR10:QCR2:QCR6:QCR7:QCR8:QCR9:RIP1 [mitochondrial membrane]
3-hydroxyacyl-CoA [endoplasmic reticulum]
N-acetyl-L-gamma-glutamyl phosphate [mitochondrion]
C-3 sterol keto reductase (4-methylzymosterol)
inositol-P-ceramide A (C26) [mitochondrion]
3-hexaprenyl-4,5-dihydroxybenzoate hydroxylase
pantetheine 4'-phosphate [mitochondrion]
protein with N-terminal(Met-Leu) [cytoplasm]
3-hexaprenyl-4-hydroxy-5-methoxybenzoate decarboxylase
1-(sn-glycero-3-phospho)-1D-myo-inositol [extracellular]
inositol phosphomannosylinositol phosphoceramide B' (C24) [endoplasmic reticulum]
5-(methylsulfanyl)-2,3-dioxopentyl phosphate [cytoplasm]
GENE_ASSOCIATION:(YCL040W or YFR053C or YGL253W)
acetyl-CoA acyltransferase (hexadecanoyl-CoA)
aldehyde dehydrogenase (isobutyl alcohol, NADP)
1-phosphatidyl-1D-myo-inositol 3-phosphate [cytoplasm]
2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine [cytoplasm]
GENE_ASSOCIATION:(YDR380W or YGR087C or YLR044C or YLR134W)
6PP-IP5 pyrophosphorylation to 5,6-PP2-IP4
4-amino-2-methyl-5-diphosphomethylpyrimidine [cytoplasm]
GENE_ASSOCIATION:(YBR127C and YDL185W and YEL027W and YEL051W and YGR020C and YHR026W and YHR039C-A and YKL080W and YLR447C and YOR270C and YOR332W and YPL234C and YPR036W)
2-hydroxyhexadecanal [endoplasmic reticulum]
inositol phosphomannosylinositol phosphoceramide C (C26) [endoplasmic reticulum]
GENE_ASSOCIATION:(YOL055C or YPL258C or YPR121W)
1D-myo-inositol 1,3,4,5-tetrakisphosphate [nucleus]
cytochrome P450 lanosterol 14-alpha-demethylase (NADP)
3-hydroxyacyl-CoA dehydratase (3-hydroxyhexacosyl-CoA)
sphingoid base-phosphate phosphatase (sphinganine 1-phosphatase)
L-sorbitol dehydrogenase (L-sorbose-producing)
alpha-D-ribose 1-phosphate [mitochondrion]
inositol-P-ceramide D (C26) [endoplasmic reticulum]
GENE_ASSOCIATION:(YBR244W or YCL035C or YDR513W or YIR037W or YKL026C)
phytosphingosine 1-phosphate [endoplasmic reticulum]
GPI-anchor assembly, step 10, GPI-modification of newly synthesised protein
GENE_ASSOCIATION:(YDR302W and YDR434W and YHR188C and YLR088W and YLR459W)
1-phosphatidyl-1D-myo-inositol [mitochondrion]
N-[(R)-4-phosphonopantothenoyl]-L-cysteine [cytoplasm]
7,8-dihydroneopterin 3'-phosphate [cytoplasm]
alpha-D-glucosamine 6-phosphate [cytoplasm]
inositol phosphomannosylinositol phosphoceramide B' (C24) [mitochondrion]
UTP-glucose-1-phosphate uridylyltransferase
nicotinate-nucleotide adenylyltransferase
adenosine 3',5'-bismonophosphate [mitochondrion]
GENE_ASSOCIATION:((YAL044C and YDR019C and YFL018C and YMR189W) or (YDR148C and YFL018C and YIL125W))
GENE_ASSOCIATION:(YDL080C or YDR380W or YGR087C or YLR044C or YLR134W)
hexacosanoyl-CoA [endoplasmic reticulum]
mannosylinositol phosphorylceramide B' (C24) [endoplasmic reticulum]
phosphoribosylpyrophosphate amidotransferase
xylitol dehydrogenase (D-xyulose-forming)
(S)-3-hydroxypalmitoyl-CoA [endoplasmic reticulum]
isocitrate dehydrogenase (NADP+), peroxisomal
1-pyrroline-3-hydroxy-5-carboxylic acid [mitochondrion]
trans-2,3-didehydroacyl-CoA [endoplasmic reticulum]
3-hydroxyacyl-CoA dehydrogenase (3-oxodecanoyl-CoA)
3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate [mitochondrion]
farnesyltransferase to proteins with CAAX motif at C-terminus, where X={ser,cys,Met,ala}
PMT1:PMT2 [endoplasmic reticulum membrane]
saccharopine dehydrogenase (NAD, L-lysine forming)
5-formyltetrahydrofolic acid [mitochondrion]
2-hydroxy-3-oxobutyl phosphate [cytoplasm]
acetyl-CoA C-acetyltransferase (octanoyl-CoA)
GENE_ASSOCIATION:(YBR068C or YBR069C or YCL025C or YDR046C or YDR508C or YKR039W)
3-hydroxyacyl-CoA dehydratase (3-hydroxydecanoyl-CoA)
ribonucleoside-triphosphate reductase (UTP)
O-mannosylated protein [endoplasmic reticulum]
2,3-bisphospho-D-glyceric acid [cytoplasm]
5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole [cytoplasm]
1-phosphatidyl-1D-myo-inositol 3-phosphate [endoplasmic reticulum]
asparagine synthase (glutamine-hydrolysing)
1,2-dioleoylglycerol [endoplasmic reticulum]
GENE_ASSOCIATION:((YDR453C and YGR209C) or (YDR453C and YLR043C))
hydrogen peroxide reductase (thioredoxin)
phytosphingosine [endoplasmic reticulum]
S-adenosyl-L-homocysteine [mitochondrion]
GENE_ASSOCIATION:(YBL030C or YBR085W or YMR056C)
D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate [cytoplasm]
1-phosphatidyl-1D-myo-inositol 4-phosphate [endoplasmic reticulum]
tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming)
alcohol acetyltransferase (isobutyl alcohol)
mannosylinositol phosphorylceramide C (C26) [endoplasmic reticulum]
inositol phosphomannosylinositol phosphoceramide C (C24) [mitochondrion]
5,6,7,8-tetrahydrofolyl-L-glutamic acid [cytoplasm]
purine-nucleoside phosphorylase (Guanosine)
GENE_ASSOCIATION:(YDR204W and YGL119W and YGR255C and YLR201C and YML110C and YOL096C and YOR125C)
tryptophan synthase (indoleglycerol phosphate)
GENE_ASSOCIATION:(YLR155C or YLR157C or YLR158C or YLR160C)
PI4,5P2:YNL047C binding to TORC2 at plasma membrane
UDP-N-acetyl-alpha-D-glucosamine [cytoplasm]
PI4,5P2:YIL105C binding to TORC2 at plasma membrane
1-phosphatidylinositol-3-phosphate 5-kinase
N-acetyl-alpha-D-glucosamine 1-phosphate [cytoplasm]
palmitoylated YEL013W [vacuolar membrane]
ceramide-1 (C24) [endoplasmic reticulum]
purine-nucleoside phosphorylase (deoxyadenosine)
alpha-D-mannosyl-beta-D-mannosyldiacetylchitobiosyldiphosphodolichol [Golgi]
phosphoribosyl-formamido-carboxamide [cytoplasm]
GENE_ASSOCIATION:(YDR536W or YFL011W or YJL219W or YLR081W or YNL318C or YOL156W)
2-keto-4-methylthiobutyrate transamination
GENE_ASSOCIATION:((YBR058C-A and YDR062W and YMR296C) or (YDR062W and YMR296C))
adenosine 3',5'-bismonophosphate [cytoplasm]
5'-phosphoribosyl-5-aminoimidazole [cytoplasm]
6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
inositol-P-ceramide D (C26) [mitochondrion]
pentadecaprenyl diphosphate [lipid particle]
5-formyltetrahydrofolic acid [extracellular]
GENE_ASSOCIATION:(YIL002C or YNL106C or YOR109W)
phosphatidylinositol 4,5-bisphosphate 5-phosphatase
1-pyrroline-3-hydroxy-5-carboxylic acid [cytoplasm]
inositol-1,4,5-triphosphate 6-kinase, nucleus
5'-phosphoribosylformyl glycinamidine synthetase
phosphatidylethanolamine [cell envelope]
4-hydroxy-2-oxoglutarate(2-) [peroxisome]
sphingolipid long chain base kinase (sphinganine)
mannosylinositol phosphorylceramide D (C26) [mitochondrion]
4-amino-4-deoxychorismate(2-) [cytoplasm]
2-hexaprenyl-6-methoxyphenol [mitochondrion]
GENE_ASSOCIATION:((YHR007C and YIL043C and YNL111C) or (YHR007C and YKL150W and YNL111C))
cytochrome P450 lanosterol 14-alpha-demethylase (NAD)
ceramide-1 (C26) [endoplasmic reticulum]
but-1-ene-1,2,4-tricarboxylic acid [mitochondrion]
purine-nucleoside phosphorylase (deoxyinosine)
1-phosphatidyl-1D-myo-inositol 3-phosphate [mitochondrion]
GENE_ASSOCIATION:((YGR209C and YLR109W) or (YLR043C and YLR109W))
(2S)-2-isopropyl-3-oxosuccinate(2-) [cytoplasm]
1-phosphatidyl-1D-myo-inositol 4-phosphate [Golgi]
geranylgeranyl diphosphate [lipid particle]
1,2-dioleoyl-sn-glycero-3-phosphocholine [endoplasmic reticulum]
NADH dehydrogenase, cytosolic/mitochondrial
1D-myo-inositol 1,4,5-trisphosphate [nucleus]
aldehyde dehydrogenase (phenylacetaldehyde, NAD)
inositol phosphomannosylinositol phosphoceramide C (C24) [Golgi]
GENE_ASSOCIATION:((YCR083W and YHR106W) or (YCR083W and YPL091W))
5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate [cytoplasm]
mannosylinositol phosphorylceramide C (C24) [mitochondrion]
hexaprenyldihydroxybenzoate methyltransferase
purine-nucleoside phosphorylase (Xanthosine)
(R)-S-lactoylglutathione [mitochondrion]
beta-D-mannosyldiacetylchitobiosyldiphosphodolichol [cytoplasm]
ceramide-3 (C26) [endoplasmic reticulum]
inositol-P-ceramide C (C24) [endoplasmic reticulum]
(2R,3R)-2,3-dihydroxy-3-methylpentanoate [mitochondrion]
aldehyde dehydrogenase (3-aminopropanal, NAD)
6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [endoplasmic reticulum]
nonaprenyl 4-hydroxybenzoate [cytoplasm]
1-phosphatidyl-1D-myo-inositol 4-phosphate [cell envelope]
5,10-methylenetetrahydrofolate(2-) [mitochondrion]
geranylgeranylated protein with AAX motif at C terminal, X={Leu,Phe} [endoplasmic reticulum]
phosphoadenylyl-sulfate reductase (thioredoxin)
GENE_ASSOCIATION:((YGR209C and YPR167C) or (YLR043C and YPR167C))
2-trans,6-trans-farnesyl diphosphate [mitochondrion]
3-hydroxyacyl-CoA dehydratase (3-hydroxytetradecanoyl-CoA)
GENE_ASSOCIATION:((Q0045 and Q0250 and Q0275 and YDL067C and YEL039C and YGL187C and YGL191W and YHR051W and YIL111W and YLR038C and YLR395C and YMR256C) or (Q0045 and Q0250 and Q0275 and YDL067C and YEL039C and YGL187C and YGL191W and YHR051W and YLR038C and YLR395C and YMR256C and YNL052W) or (Q0045 and Q0250 and Q0275 and YDL067C and YGL187C and YGL191W and YHR051W and YIL111W and YJR048W and YLR038C and YLR395C and YMR256C) or (Q0045 and Q0250 and Q0275 and YDL067C and YGL187C and YGL191W and YHR051W and YJR048W and YLR038C and YLR395C and YMR256C and YNL052W))
AVO1:AVO2:BIT61:LST8:TOR2:TSC11 [cell envelope]
4PP-IP5 pyrophosphorylation to 4,5-PP2-IP4
VMA1:VMA10:VMA11:VMA13:VMA16:VMA2:VMA3:VMA4:VMA5:VMA6:VMA7:VMA8:VPH1 [vacuolar membrane]
C-terminal processing of farnesylated proteins II
N-acetyl-L-glutamate(2-) [mitochondrion]
2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol [mitochondrion]
ceramide-4 (C26) [endoplasmic reticulum]
ceramide-2' (C24) [endoplasmic reticulum]
5PP-IP5 pyrophosphorylation to 5,6-PP2-IP4
inositol-P-ceramide A (C24) [endoplasmic reticulum]
acetylated protein with terminal(Met-Phe) [cytoplasm]
mannosylinositol phosphorylceramide D (C26) [Golgi]
3-(4-hydroxyphenyl)pyruvate [mitochondrion]
D-fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase
acylglycerone phosphate [endoplasmic reticulum]
GENE_ASSOCIATION:(YKL127W or YMR105C or YMR278W)
4-(phosphonooxy)-L-threonine [cytoplasm]
inositol phosphomannosylinositol phosphoceramide B (C24) [Golgi]
glycerol-3-phosphate dehydrogenase (fad)
YHR005C, myristoylated at G2 [cytoplasm]
mannosylinositol phosphorylceramide A (C26) [mitochondrion]
ergosteryl palmitoleate [endoplasmic reticulum]
GENE_ASSOCIATION:((YHL003C and YMR298W) or (YKL008C and YMR298W))
3-oxotetracosanoyl-CoA [endoplasmic reticulum]
inositol phosphomannosylinositol phosphoceramide B' (C26) [Golgi]
aldehyde dehydrogenase (2-phenylethanol, NAD)
GENE_ASSOCIATION:(YBR296C or YCR037C or YJL198W or YML123C or YNR013C)
CDP-diacylglycerol [endoplasmic reticulum]
5-O-(1-carboxyvinyl)-3-phosphoshikimic acid [cytoplasm]
episteryl palmitoleate [endoplasmic reticulum]
3-oxohexacosanoyl-CoA [endoplasmic reticulum]
3-hydroxy-2-isopropyl-4-methoxy-4-oxobutanoate [cytoplasm]
mannosylinositol phosphorylceramide C (C24) [endoplasmic reticulum]
3-hydroxyacyl-CoA dehydrogenase (3-oxohexacosyl-CoA)
inositol-P-ceramide C (C26) [mitochondrion]
GENE_ASSOCIATION:(YBR069C or YCL025C or YDR046C or YDR508C or YKR039W)
protein with CAAX motif at C terminal, X={Leu,Phe} [endoplasmic reticulum]
beta-D-fructose 2,6-bisphosphate [cytoplasm]
inositol-P-ceramide B' (C26) [mitochondrion]
(2E)-3-(methoxycarbonyl)pent-2-enedioic acid [cytoplasm]
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [mitochondrion]
L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)
geranylgeranylated protein with hydroxyl C-terminal [endoplasmic reticulum]
5,10-methylenetetrahydrofolate(2-) [cytoplasm]
2-trans,6-trans-farnesyl diphosphate [cytoplasm]
6-O-{alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
UDP-glucose:ergosterol glucosyltransferase
1-phosphatidyl-1D-myo-inositol 4-phosphate [cytoplasm]
nonadecaprenyl diphosphate [lipid particle]
undecaprenyl diphosphate [lipid particle]
inositol phosphomannosylinositol phosphoceramide D (C26) [mitochondrion]
adenosylmethionine-8-amino-7-oxononanoate transaminase
acetylated protein with terminal(Met-Leu) [cytoplasm]
heptaprenyl diphosphate [lipid particle]
glycerophosphodiester phosphodiesterase (glycerophosphocholine)
3-hydroxyoctadecanoyl-CoA [endoplasmic reticulum]
GENE_ASSOCIATION:(YCR034W and YDL015C and YLR372W)
inositol phosphomannosylinositol phosphoceramide B (C24) [endoplasmic reticulum]
GENE_ASSOCIATION:(YDR536W or YGL084C or YPL189W)
lanosteryl palmitoleate [endoplasmic reticulum]
1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate [cytoplasm]
aldehyde dehydrogenase (2-methylbutanol, NADP)
GENE_ASSOCIATION:(YCR105W or YDR368W or YMR318C)
tetrahydropteroyltri-L-glutamic acid [cytoplasm]
inositol phosphomannosylinositol phosphoceramide B' (C26) [endoplasmic reticulum]
sn-glycero-3-phosphocholine [cell envelope]
YHR005C, myristoylated at G2, palmitoylated at C3 [cytoplasm]
mannosylinositol phosphorylceramide B (C24) [endoplasmic reticulum]
erythro-4-hydroxy-L-glutamic acid [cytoplasm]
3-oxotetradecanoyl-CoA [endoplasmic reticulum]
saccharopine dehydrogenase (NADP, L-glutamate forming)
mannosylinositol phosphorylceramide C (C24) [Golgi]
ergosta-5,7,22,24(28)-tetraen-3beta-ol [cytoplasm]
3-oxodocosanoyl-CoA [endoplasmic reticulum]
3-hexaprenyl-4-hydroxybenzoic acid [mitochondrion]
inositol-P-ceramide D (C24) [endoplasmic reticulum]
6-O-phosphono-D-glucono-1,5-lactone [cytoplasm]
geranylgeranylated protein with methylated C-terminal [endoplasmic reticulum]
phosphatidylethanolamine methyltransferase
acetylated protein with terminal(Met-Ile) [cytoplasm]
GENE_ASSOCIATION:(YBR127C and YDL185W and YEL027W and YEL051W and YGR020C and YHR026W and YHR039C-A and YKL080W and YLR447C and YMR054W and YOR332W and YPL234C and YPR036W)
hypoxanthine phosphoribosyltransferase (Hypoxanthine)
O-glycosylation of proteins by PMT1:PMT2
GENE_ASSOCIATION:(YDR376W and YER141W and YPL252C)
acylglycerone phosphate [lipid particle]
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [nucleus]
(S)-3-hydroxyhexacosanoyl-CoA [peroxisome]
1-(5-phospho-D-ribosyl)-5-[(5-phospho-D-ribosylamino)methylideneamino]imidazole-4-carboxamide [cytoplasm]
GENE_ASSOCIATION:(YDR384C or YGR121C or YNL142W or YPR138C)
ergosta-5,7,22,24(28)-tetraen-3beta-ol [endoplasmic reticulum]
Ras protein with CaaX motif at C terminal, a=aliphatic residue, X=any residue [endoplasmic reticulum]
protein with dicysteine at C-terminal [cytoplasm]
inositol phosphomannosylinositol phosphoceramide A (C26) [mitochondrion]
5-phospho-ribosyl-glycineamide [cytoplasm]
3-hydroxyicosanoyl-CoA [endoplasmic reticulum]
2-hexaprenyl-6-methoxyphenol monooxygenase
S-adenosyl-L-methionine [endoplasmic reticulum]
5-diphosphoinositol-1,2,3,4,6-pentakisphosphate synthase
GENE_ASSOCIATION:(YBR068C or YCL025C or YDR046C or YKR039W or YOL020W)
1-phosphatidyl-1D-myo-inositol [cytoplasm]
GENE_ASSOCIATION:((YGR209C and YIL010W) or (YIL010W and YLR043C))
succinate-semialdehyde dehydrogenase (NADP)
3-hydroxy-3-methylglutaryl-CoA [mitochondrion]
3-(4-hydroxyphenyl)pyruvate [peroxisome]
GENE_ASSOCIATION:(YBR221C and YER178W and YFL018C and YGR193C and YNL071W)
GENE_ASSOCIATION:((Q0080 and Q0085 and Q0130 and YBL099W and YBR039W and YDL004W and YDR298C and YDR322C-A and YDR377W and YJR121W and YKL016C and YLR295C and YML081C-A and YPL078C and YPL271W) or (Q0080 and Q0085 and Q0130 and YBL099W and YBR039W and YDL004W and YDR298C and YDR377W and YJR121W and YKL016C and YLR295C and YML081C-A and YPL078C and YPL271W and YPR020W))
inositol phosphomannosylinositol phosphoceramide C (C24) [endoplasmic reticulum]
3-oxopalmitoyl-CoA [endoplasmic reticulum]
S-adenosyl-methionine delta-24-sterol-c-methyltransferase
mannosylinositol phosphorylceramide A (C26) [endoplasmic reticulum]
dolichyl-phosphate-mannose--protein mannosyltransferase
GENE_ASSOCIATION:(YDL093W or YJR143C or YOR321W or (YAL023C and YDL095W))
inositol phosphomannosylinositol phosphoceramide D (C26) [Golgi]
3-hexaprenyl-4,5-dihydroxybenzoate transport
C-terminal processing of geranylgeranylated proteins II
GENE_ASSOCIATION:(YHR216W or YLR432W or YML056C)
stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA)
3-hydroxyacyl-CoA dehydratase (3-hydroxyhexadecanoyl-CoA)
6-O-{2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
methylenetetrahydrofolate dehydrogenase (NADP)
ceramide-4 (C24) [endoplasmic reticulum]
inositol-P-ceramide B' (C26) [endoplasmic reticulum]
GENE_ASSOCIATION:(YBR068C or YBR069C or YDR046C or YKR039W or YOL020W)
GENE_ASSOCIATION:((YCR024C-A and YEL017C-A and YGL008C) or (YCR024C-A and YEL017C-A and YPL036W))
beta-D-mannosyldiacetylchitobiosyldiphosphodolichol [Golgi]
pantetheine-phosphate adenylyltransferase
inositol-P-ceramide B (C24) [endoplasmic reticulum]
GAA1:GAB1:GPI16:GPI17:GPI8 [endoplasmic reticulum]
O-phosphoethanolamine [endoplasmic reticulum]
fatty acyl-ACP synthase (n-C8:0ACP), lumped reaction
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [vacuole]
(S)-3-hydroxyhexacosanoyl-CoA [endoplasmic reticulum]
2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate [cytoplasm]
(R)-5-diphosphomevalonic acid [cytoplasm]
2-deoxy-D-ribofuranose 1-phosphate [cytoplasm]
ergosta-5,7,24(28)-trien-3beta-ol [cytoplasm]
inositol phosphomannosylinositol phosphoceramide A (C26) [Golgi]
protein with CAAX motif at C terminal, X={Ser,Cys,Met,Ala} [endoplasmic reticulum]
carbamoyl-phosphate synthase (glutamine-hydrolysing)
GENE_ASSOCIATION:(YJL130C or (YJR109C and YOR303W))
(R)-lactate:ferricytochrome-c 2-oxidoreductase
GENE_ASSOCIATION:((YDL174C and YEL039C) or (YDL174C and YJR048W) or (YEL039C and YEL071W) or (YEL071W and YJR048W))
GENE_ASSOCIATION:(YCL025C or YDR508C or YFL055W or YKR039W or YPL265W)
3-hydroxy-3-methylglutaryl-CoA [cytoplasm]
UDPglucose--hexose-1-phosphate uridylyltransferase
GENE_ASSOCIATION:((YDL178W and YEL039C) or (YDL178W and YJR048W))
3-hydroxydocosanoyl-CoA [endoplasmic reticulum]
GENE_ASSOCIATION:(YBR068C or YBR069C or YCL025C or YDR046C or YKR039W or YOL020W)
3-hydroxyacyl-CoA dehydrogenase (3-oxohexadecanoyl-CoA)
inositol-1,3,4,5,6-pentakisphosphate 2-kinase
1-pyrroline-5-carboxylate [mitochondrion]
inositol phosphomannosylinositol phosphoceramide B' (C26) [mitochondrion]
mannosylinositol phosphorylceramide A (C26) [Golgi]
ergosteryl oleate [endoplasmic reticulum]
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [cytoplasm]
GENE_ASSOCIATION:(YBR205W or YBR199W or YDR483W or YJL139C or YKR061W or YNL029C or YOR099W or YPL053C)
mannosylinositol phosphorylceramide B' (C24) [mitochondrion]
(R)-4'-phosphopantothenic acid [cytoplasm]
3-hexaprenyl-4,5-dihydroxybenzoic acid [mitochondrion]
7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid [cytoplasm]
erythro-4-hydroxy-L-glutamic acid [peroxisome]
S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase
1-phosphatidyl-1D-myo-inositol [cell envelope]
GENE_ASSOCIATION:(YCL025C or YDR508C or YKR039W or YPL265W)
diphosphoinositol-1,3,4,6-tetrakisphosphate diphosphohydrolase
STV1:VMA1:VMA10:VMA11:VMA13:VMA16:VMA2:VMA3:VMA4:VMA5:VMA6:VMA7:VMA8 [Golgi membrane]
L-aminoadipate-semialdehyde dehydrogenase (NADH)
mannosylinositol phosphorylceramide B (C26) [endoplasmic reticulum]
secretory protein with appropriate seryl or threonyl group [endoplasmic reticulum]
(S)-3-methyl-2-oxopentanoate [mitochondrion]
ribonucleoside-triphosphate reductase (GTP)
N,N'-diacetylchitobiosyldiphosphodolichol [cytoplasm]
5-formethyltetrahydrofolate cyclo-ligase
GENE_ASSOCIATION:(YFL055W or YKR039W or YPL265W)
mannosylinositol phosphorylceramide D (C26) [endoplasmic reticulum]
ceramide-3 (Phytosphingosine:n-C24:0OH) transport
inositol-1,4,5-trisphosphate 3-kinase, nucleus
ceramide-2' (sphinganine:n-C26:0OH) transport
farnesylated protein with hydroxyl C-terminal [endoplasmic reticulum]
3-hydroxyacyl-CoA dehydrogenase (3-oxooctadecanoyl-CoA)
inositol-P-ceramide B (C26) [endoplasmic reticulum]
ceramide-3 (Phytosphingosine:n-C26:0OH) transport
fatty acid synthase (n-C24:0), lumped reaction
GENE_ASSOCIATION:(YGR192C or YJL052W or YJR009C)
glyceraldehyde-3-phosphate dehydrogenase
GENE_ASSOCIATION:(YBR068C or YCL025C or YDR046C or YKR039W or YOL020W or YOR348C or YPL265W)
ceramide-2' (sphinganine:n-C24:0OH) transport
GENE_ASSOCIATION:(YBR023C or YBR038W or YNL192W)
acetyl-CoA acyltransferase (tetracosanoyl-CoA)
diphosphoinositol-1,3,4,6-tetrakisphosphate synthase
GPI14:PBN1 [endoplasmic reticulum membrane]
2-acetamido-5-oxopentanoate [mitochondrion]
6-diphospho-1D-myo-inositol pentakisphosphate [cytoplasm]
nicotinamide-nucleotide adenylyltransferase
S(8)-aminomethyldihydrolipoylprotein [mitochondrion]
2-deoxy-D-ribose 5-phosphate [cytoplasm]
1-(sn-glycero-3-phospho)-1D-myo-inositol [cytoplasm]
mannose-(1D-myo-inositol 1-phosphate)2 [endoplasmic reticulum]
protein with N-terminal(Met-Glu) [cytoplasm]
coproporphyrinogen oxidase (O2 required)
(R)-2,3-dihydroxy-3-methylbutanoate [mitochondrion]
3-hexaprenyl-4,5-dihydroxybenzoic acid [cytoplasm]
L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase
mannosylinositol phosphorylceramide B' (C26) [endoplasmic reticulum]
L-aminoadipate-semialdehyde dehydrogenase (NADPH)
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [endoplasmic reticulum]
inositol phosphomannosylinositol phosphoceramide A (C24) [endoplasmic reticulum]
(S)-2-acetyl-2-hydroxybutanoate [mitochondrion]
inositol-P-ceramide B (C24) [mitochondrion]
purine-nucleoside phosphorylase (deoxyguanosine)
dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate)
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase (NADPH)
palmitoylated Ras protein [endoplasmic reticulum]
aldehyde dehydrogenase (isobutyl alcohol, NAD)
inositol phosphomannosylinositol phosphoceramide B (C26) [Golgi]
GENE_ASSOCIATION:(YCL025C or YKR039W or YOL020W or YOR348C or YPL265W)
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol [cytoplasm]
acetyl-CoA C-acetyltransferase (dodecanoyl)
deoxyhypusine synthase, cytosolic/mitochondrial
mannosylinositol phosphorylceramide B (C26) [Golgi]
farnesyl diphosphate [endoplasmic reticulum]
4-diphospho-1D-myo-inositol pentakisphosphate [cytoplasm]
alcohol acetyltransferase (2-methylbutanol)
P1-(5'-adenosyl),P4-(5'-guanosyl) tetraphosphate [cytoplasm]
farnesylated protein with methylated C-terminal [endoplasmic reticulum]
3-(imidazol-4-yl)-2-oxopropyl dihydrogen phosphate [cytoplasm]
zymosteryl oleate [endoplasmic reticulum]
6-O-[alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
3-hydroxyacyl-CoA dehydratase (3-hydroxyoctadecanoyl-CoA)
protein with GPI signal [endoplasmic reticulum membrane]
ceramide-3 (C24) [endoplasmic reticulum]
inositol-P-ceramide C (C26) [endoplasmic reticulum]
mannose-(1D-myo-inositol 1-phosphate)2 [mitochondrion]
aldehyde dehydrogenase (2-phenylethanol, NADP)
GENE_ASSOCIATION:((YFR015C and YJL137C) or (YFR015C and YKR058W) or (YJL137C and YLR258W) or (YKR058W and YLR258W))
glycerophosphatidylethanolamine [cell envelope]
acetyl-CoA C-acyltransferase (decanoyl-CoA)
inositol phosphomannosylinositol phosphoceramide D (C26) [endoplasmic reticulum]
farnesylated protein with AAX motif at C terminal, X={Ser,Cys,Met,Ala} [endoplasmic reticulum]
purine-nucleoside phosphorylase (inosine)
mannose-1D-myo-inositol 1-phosphate [endoplasmic reticulum]
mannosylinositol phosphorylceramide B' (C26) [Golgi]
(N(omega)-L-arginino)succinic acid [cytoplasm]
3-hexaprenyl-4-hydroxybenzoic acid [cytoplasm]
phosphatidyl-N-methylethanolamine [mitochondrion]
ERF2:SHR5 [endoplasmic reticulum membrane]
sedoheptulose 1,7-bisphosphate [cytoplasm]
fatty acid synthase (n-C8:0), lumped reaction
2-trans,6-trans,10-trans-geranylgeranyl diphosphate [cytoplasm]
mannosylinositol phosphorylceramide D (C24) [Golgi]
C-terminal processing of geranylgeranylated proteins I
myo-inositol hexakisphosphate [cytoplasm]
1-C-(indol-3-yl)glycerol 3-phosphate [cytoplasm]
(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate [mitochondrion]
inositol phosphomannosylinositol phosphoceramide B (C26) [endoplasmic reticulum]
L-4-hydroxyglutamic semialdehyde [mitochondrion]
5-methyltetrahydrofolate(2-) [cytoplasm]
aldehyde dehydrogenase (acetylaldehyde, NAD)
alpha-D-galactose 1-phosphate [cytoplasm]
mannosylinositol phosphorylceramide B (C24) [Golgi]
3-hydroxyacyl-CoA dehydrogenase (3-oxotetradecanoyl-CoA)
phosphatidylinositol 3-phosphate phosphatase
GENE_ASSOCIATION:(YJR110W or YNL106C or YOR109W)
C-4 sterol methyl oxidase (4,4-dimethylzymosterol)
inositol-P-ceramide B (C26) [mitochondrion]
inositol-P-ceramide C (C24) [mitochondrion]
acylation of GPI inositol at 2 position, GPI-anchor assembly, step 3
4-methyl-5-(2-phosphonooxyethyl)thiazole [cytoplasm]
2-oxoadipate and 2-oxoglutarate transport
6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
GCV1:GCV2:GCV3:PDA1:PDB1 [mitochondrion]
dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate)
2-(3-amino-3-carboxypropyl)-L-histidine [cytoplasm]
COX1:COX12:COX13:COX2:COX3:COX4:COX5B:COX6:COX7:COX8:COX9:CYC7 [mitochondrial membrane]
3-hydroxyacyl-CoA dehydratase (3-hydroxydodecanoyl-CoA)
heptadecaprenyl diphosphate [lipid particle]
zymosteryl palmitoleate [endoplasmic reticulum]
ribonucleoside-triphosphate reductase (CTP)
erythro-4-hydroxy-L-glutamic acid [mitochondrion]
3-oxooctadecanoyl-CoA [endoplasmic reticulum]
acetylated protein with terminal(Met-Trp) [cytoplasm]
5-amino-6-(D-ribitylamino)uracil [cytoplasm]
uroporphyrinogen decarboxylase (uroporphyrinogen III)
3-oxoicosanoyl-CoA [endoplasmic reticulum]
7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid [mitochondrion]
N-acetylglucosamine-6-phosphate synthase
inositol phosphomannosylinositol phosphoceramide D (C24) [mitochondrion]
5,10-methylenetetrahydrofolatereductase (NADPH)
3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid [mitochondrion]
mannosylinositol phosphorylceramide B' (C26) [mitochondrion]
GENE_ASSOCIATION:((YIL043C and YMR015C and YNL111C) or (YKL150W and YMR015C and YNL111C))
phosphatidyl-N-methylethanolamine [endoplasmic reticulum]
3-hydroxytetracosanoyl-CoA [endoplasmic reticulum]
CAT5:COQ3:COQ4:COQ5:COQ6:COQ8:COQ9 [mitochondrion]
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [cell envelope]
mannose-1D-myo-inositol 1-phosphate [mitochondrion]
GENE_ASSOCIATION:(YEL063C or YKR039W or YNL270C)
docosaprenyl diphosphate [lipid particle]
glycylpeptide N-tetradecanoyltransferase
mannosylinositol phosphorylceramide D (C24) [mitochondrion]
episteryl oleate [endoplasmic reticulum]
dolichyl phosphate [endoplasmic reticulum]
icosaprenyl diphosphate [lipid particle]
ACP1:CEM1:ETR1:HTD2:MCT1:OAR1 [mitochondrion]
mannosylinositol phosphorylceramide B (C24) [mitochondrion]
GENE_ASSOCIATION:(YBR069C or YGR191W or YKR039W)
GENE_ASSOCIATION:((YHL011C and YKL181W) or (YER099C and YOL061W) or (YBL068W and YOL061W))
D1-pyrroline-5-carboxylate dehydrogenase
formate dehydrogenase, cytosolic/mitochondrial
5PP-IP5 pyrophosphorylation to 4,5-PP2-IP4
alpha,alpha-trehalose 6-phosphate [cytoplasm]
aldehyde dehydrogenase (acetylaldehyde, NADP)
(S)-2,3-epoxysqualene [endoplasmic reticulum]
3-dehydro-4-methylzymosterol [cytoplasm]
sphinganine 1-phosphate [endoplasmic reticulum]
5-methyltetrahydropteroyltri-L-glutamic acid [cytoplasm]
GENE_ASSOCIATION:(YDR261C or YGR282C or YLR300W or YNR067C or YOR190W)
GENE_ASSOCIATION:(YCL025C or YFL055W or YKR039W or YPL265W)
inositol-1,4,5,6- tetrakisphosphate 3-kinase, nucleus
protein with N-terminal(Met-Ile) [cytoplasm]
4,5-bis(diphospho)-1D-myo-inositol tetrakisphosphate [cytoplasm]
inositol phosphomannosylinositol phosphoceramide B (C24) [mitochondrion]
4-methyl-2-oxopentanoate [mitochondrion]
2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase
henicosaprenyl diphosphate [lipid particle]
isopentenyl diphosphate [lipid particle]
S(8)-aminomethyldihydrolipoamide [mitochondrion]
galactose-1-phosphate uridylyltransferase
6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol [endoplasmic reticulum]
2-[3-carboxy-3-(methylammonio)propyl]-L-histidine [cytoplasm]