520913
stoichiometry: 1.0
species: 336403
type: SpeciesReference

361507
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialinnermembrane
type: Species

493504
stoichiometry: 1.0
species: 321540
type: SpeciesReference

345560
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

463845
stoichiometry: 1.0
species: 321274
type: SpeciesReference

525589
stoichiometry: 1.0
species: 322856
type: SpeciesReference

391154
stoichiometry: 1.0
species: 323766
type: SpeciesReference

475266
stoichiometry: 1.0
species: 325137
type: SpeciesReference

574321
stoichiometry: 1.0
species: 325113
type: SpeciesReference

528879
stoichiometry: 1.0
species: 321200
type: SpeciesReference

489388
stoichiometry: 1.0
species: 321163
type: SpeciesReference

434842
stoichiometry: 1.0
species: 335420
type: SpeciesReference

528303
stoichiometry: 1.0
species: 335947
type: SpeciesReference

538478
stoichiometry: 1.0
species: 351345
type: SpeciesReference

387002
stoichiometry: 1.0
species: 323429
type: SpeciesReference

470731
stoichiometry: 1.0
species: 321274
type: SpeciesReference

446166
stoichiometry: 1.0
species: 331808
type: SpeciesReference

R2236 c
fast: false
is: SBO:0000176
product: 535166
name: S-adenosyl-L-methionine:6-thioguanosine monophosphate S-methyltransferase [cytosol]
reversible: true
is: R08246
type: Reaction
is part of: http://identifiers.org/ec-code/2.1.1.67
product: 535154
reactant: 535130
modifier: 535178
reactant: 535142

371223
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

357308
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

512358
stoichiometry: 1.0
species: 348981
type: SpeciesReference

447114
stoichiometry: 1.0
species: 332240
type: SpeciesReference

533547
stoichiometry: 1.0
species: 322025
type: SpeciesReference

476418
stoichiometry: 1.0
species: 342171
type: SpeciesReference

379635
stoichiometry: 4.0
species: 325101
type: SpeciesReference

432310
stoichiometry: 1.0
species: 321163
type: SpeciesReference

389354
stoichiometry: 1.0
species: 322121
type: SpeciesReference

R1097 m
name: ATP:dUDP phosphotransferase [mitochondria]
product: 444306
is part of: http://identifiers.org/ec-code/2.7.4.6
is: R02331
is: SBO:0000176
fast: false
reactant: 444270
modifier: 444318
product: 444294
reversible: true
type: Reaction
reactant: 444282

344192
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

368619
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

R2241 r
fast: false
modifier: 535550
modifier: 535538
reactant: 535478
name: [endoplasmic reticulum membrane]
modifier: 535526
is part of: http://identifiers.org/ec-code/1.14.14.1
is: R08256
type: Reaction
is: SBO:0000176
modifier: 535514
reversible: true
product: 535490
modifier: 535502

562170
stoichiometry: 1.0
species: 336571
type: SpeciesReference

442051
stoichiometry: 1.0
species: 333668
type: SpeciesReference

488945
stoichiometry: 1.0
species: 343405
type: SpeciesReference

444930
stoichiometry: 1.0
species: 321588
type: SpeciesReference

453059
stoichiometry: 1.0
species: 333368
type: SpeciesReference

437687
stoichiometry: 1.0
species: 334280
type: SpeciesReference

323381
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

492448
stoichiometry: 1.0
species: 321455
type: SpeciesReference

345776
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

541934
stoichiometry: 1.0
species: 351657
type: SpeciesReference

R131 cl
product: 377055
reactant: 377043
is: SBO:0000185
fast: false
reversible: false
name: Transport of IDP [lysosomal membrane]
type: Reaction

R1809 r
reactant: 500863
name: [endoplasmic reticulum membrane]
modifier: 500899
product: 500887
product: 500875
is: SBO:0000176
is: R05918
type: Reaction
fast: false
reversible: true
reactant: 500851

500047
stoichiometry: 1.0
species: 353373
type: SpeciesReference

363199
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

R385 m
name: Acetyl-CoA:glycine C-acetyltransferase [mitochondria]
reversible: true
reactant: 392677
type: Reaction
is: R00371
modifier: 392725
product: 392713
product: 392701
is: SBO:0000176
reactant: 392689
is part of: http://identifiers.org/ec-code/2.3.1.29
fast: false

367348
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

433918
stoichiometry: 1.0
species: 339212
type: SpeciesReference

330781
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

323986
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

499855
stoichiometry: 1.0
species: 321274
type: SpeciesReference

513628
stoichiometry: 1.0
species: 328660
type: SpeciesReference

441751
stoichiometry: 1.0
species: 321187
type: SpeciesReference

R2026 p
is: R07084
is: SBO:0000176
reversible: false
modifier: 519197
product: 519184
name: 7,8-dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene hydrolase [peroxisome]
reactant: 519145
product: 519171
type: Reaction
is part of: http://identifiers.org/ec-code/2.5.1.18
reactant: 519158
fast: false

460102
stoichiometry: 1.0
species: 322013
type: SpeciesReference

515235
stoichiometry: 1.0
species: 328660
type: SpeciesReference

431482
stoichiometry: 1.0
species: 330853
type: SpeciesReference

441607
stoichiometry: 1.0
species: 334676
type: SpeciesReference

522436
stoichiometry: 1.0
species: 323998
type: SpeciesReference

434554
stoichiometry: 1.0
species: 321903
type: SpeciesReference

346352
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

549260
stoichiometry: 1.0
species: 354248
type: SpeciesReference

R488 c
modifier: 400463
reactant: 400427
type: Reaction
name: L-phenylalanine:oxygen oxidoreductase (decarboxylating) [cytosol]
is: SBO:0000176
reversible: false
is part of: http://identifiers.org/ec-code/1.11.1.7
is: R00698
fast: false
reactant: 400415
product: 400451
product: 400439

576529
stoichiometry: 1.0
species: 323658
type: SpeciesReference

330382
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

391441
stoichiometry: 1.0
species: 322061
type: SpeciesReference

524754
stoichiometry: 1.0
species: 340076
type: SpeciesReference

406594
stoichiometry: 1.0
species: 322539
type: SpeciesReference

R2209 n
type: Reaction
name: acyl-CoA thioesterase family protein [nucleus]
is: SBO:0000176
reactant: 533295
is: R08181
product: 533307
is part of: http://identifiers.org/ec-code/3.1.2.2
modifier: 533331
product: 533319
reactant: 533283
fast: false
reversible: false

577909
stoichiometry: 1.0
species: 324980
type: SpeciesReference

524689
stoichiometry: 1.0
species: 340076
type: SpeciesReference

491896
stoichiometry: 1.0
species: 344036
type: SpeciesReference

387506
stoichiometry: 1.0
species: 322013
type: SpeciesReference

R1207 c
modifier: 453371
reversible: false
type: Reaction
is: SBO:0000176
reactant: 453323
name: XTP pyrophosphohydrolase [cytosol]
is: R02720
fast: false
is part of: http://identifiers.org/ec-code/3.6.1.19
product: 453347
reactant: 453335
product: 453359

377823
stoichiometry: 1.0
species: 335408
type: SpeciesReference

372327
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialoutermembrane
type: Species

367132
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

324643
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R607 c
is: SBO:0000176
is: R00988
is part of: http://identifiers.org/ec-code/3.5.1.9
type: Reaction
product: 409354
fast: false
modifier: 409378
reactant: 409342
product: 409366
name: N-Formylanthranilate amidohydrolase [cytosol]
reversible: true
reactant: 409330

359984
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialoutermembrane
type: Species

338023
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

360176
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

572977
stoichiometry: 1.0
species: 334292
type: SpeciesReference

467013
stoichiometry: 1.0
species: 338349
type: SpeciesReference

532059
stoichiometry: 1.0
species: 350949
type: SpeciesReference

549980
stoichiometry: 1.0
species: 345464
type: SpeciesReference

543357
stoichiometry: 1.0
species: 321212
type: SpeciesReference

575137
stoichiometry: 1.0
species: 326396
type: SpeciesReference

R415 g
name: UDP-galactose:D-glucose 4-beta-D-galactosyltransferase [Golgi membrane]
modifier: 394981
product: 394969
modifier: 394993
reactant: 394933
is part of: http://identifiers.org/ec-code/2.4.1.22
reactant: 394945
modifier: 395005
product: 394957
is: SBO:0000176
fast: false
type: Reaction
reversible: true
is: R00503

R2105 c
name: FK (FACKEL); delta14-sterol reductase [endoplasmic reticulum membrane]
type: Reaction
product: 526132
is: SBO:0000176
modifier: 526144
reversible: false
reactant: 526096
product: 526120
is: R07483
reactant: 526108
reactant: 526084
is part of: http://identifiers.org/ec-code/1.3.1.70
fast: false

501691
stoichiometry: 1.0
species: 353637
type: SpeciesReference

R2336 c
product: 545468
reactant: 545432
type: Reaction
reversible: true
reactant: 545420
is: R08408
fast: false
product: 545444
reactant: 545408
is part of: http://identifiers.org/ec-code/1.2.3.1
modifier: 545480
product: 545456
is: SBO:0000176
name: Aldehyde:oxygen oxidoreductase [cytosol]

347013
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

410325
stoichiometry: 1.0
species: 321187
type: SpeciesReference

490084
stoichiometry: 1.0
species: 334376
type: SpeciesReference

354632
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R2168 p
is part of: http://identifiers.org/ec-code/1.3.3.6
name: ACX3 (ACYL-COA OXIDASE 3); acyl-CoA oxidase [peroxisome]
is: SBO:0000176
product: 530583
modifier: 530619
modifier: 530607
type: Reaction
reactant: 530559
reversible: false
is: R07892
product: 530595
fast: false
reactant: 530571

458794
stoichiometry: 1.0
species: 334760
type: SpeciesReference

496161
stoichiometry: 1.0
species: 321515
type: SpeciesReference

R552 c
modifier: 405310
modifier: 405298
fast: false
reactant: 405262
is: R00891
is part of: http://identifiers.org/ec-code/4.2.1.22
product: 405286
is: SBO:0000176
product: 405274
reversible: true
reactant: 405250
type: Reaction
name: L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming) [cytosol]

447954
stoichiometry: 1.0
species: 322097
type: SpeciesReference

456598
stoichiometry: 1.0
species: 325125
type: SpeciesReference

521069
stoichiometry: 1.0
species: 323949
type: SpeciesReference

440503
stoichiometry: 1.0
species: 333200
type: SpeciesReference

365695
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

578844
stoichiometry: 1.0
species: 329781
type: SpeciesReference

528183
stoichiometry: 1.0
species: 350637
type: SpeciesReference

473515
stoichiometry: 1.0
species: 321515
type: SpeciesReference

559170
stoichiometry: 1.0
species: 328060
type: SpeciesReference

346723
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

322025
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

R1002 c
reactant: 437362
reactant: 437375
name: CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase [plasma membrane]
is part of: http://identifiers.org/ec-code/2.7.8.1
reversible: false
product: 437388
is: SBO:0000176
fast: false
is: R02057
type: Reaction
modifier: 437414
product: 437401

557911
stoichiometry: 1.0
species: 321163
type: SpeciesReference

321625
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

372999
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosomalmembrane
type: Species

489580
stoichiometry: 1.0
species: 343556
type: SpeciesReference

437570
stoichiometry: 1.0
species: 331700
type: SpeciesReference

470237
stoichiometry: 1.0
species: 337159
type: SpeciesReference

369495
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialinnermembrane
type: Species

R1437 c
is: SBO:0000176
reactant: 471451
type: Reaction
name: lanosterol delta24-reductase [endoplasmic reticulum membrane]
fast: false
is: R03689
product: 471475
reactant: 471439
reactant: 471427
reversible: true
is part of: http://identifiers.org/ec-code/1.3.1.72
product: 471463
modifier: 471487

503623
stoichiometry: 1.0
species: 341784
type: SpeciesReference

332156
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

362023
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

324338
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

423324
stoichiometry: 1.0
species: 324667
type: SpeciesReference

459946
stoichiometry: 1.0
species: 334868
type: SpeciesReference

336115
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

329593
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

513511
stoichiometry: 2.0
species: 323962
type: SpeciesReference

R2079 c
name: Plasmenylethanolamine 2-acylhydrolase [endoplasmic reticulum membrane]
reactant: 524359
product: 524396
is: R07379
is part of: http://identifiers.org/ec-code/3.1.1.4
fast: false
reactant: 524371
is: SBO:0000176
type: Reaction
product: 524384
modifier: 524408
reversible: true

R2015 r
type: Reaction
is: R07079
modifier: 517864
is: SBO:0000176
product: 517828
reactant: 517768
modifier: 517840
modifier: 517876
reversible: true
is part of: http://identifiers.org/ec-code/1.14.14.1
modifier: 517852
reactant: 517792
name: Benzpyrene, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing) [endoplasmic reticulum membrane]
reactant: 517756
product: 517804
fast: false
modifier: 517888
reactant: 517780
product: 517816

508998
stoichiometry: 1.0
species: 348309
type: SpeciesReference

544028
stoichiometry: 1.0
species: 327424
type: SpeciesReference

467661
stoichiometry: 1.0
species: 336751
type: SpeciesReference

416209
stoichiometry: 1.0
species: 322856
type: SpeciesReference

R2350 m
modifier: 546644
reactant: 546608
reversible: true
fast: false
modifier: 546632
is: R08758
type: Reaction
name: [mitochondrial inner membrane]
product: 546620
is part of: http://identifiers.org/ec-code/1.14.13.15
is: SBO:0000176

322171
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

R1692 c
name: 3-Methoxy-4-hydroxyphenylglycolaldehyde:NAD+ oxidoreductase [cytosol]
reactant: 491776
reactant: 491800
is: SBO:0000176
is: R04891
type: Reaction
modifier: 491848
product: 491836
product: 491812
reactant: 491788
fast: false
modifier: 491860
is part of: http://identifiers.org/ec-code/1.2.1.5
reversible: true
product: 491824

R1746 c
modifier: 496005
is: R05050
is: SBO:0000176
is part of: http://identifiers.org/ec-code/1.2.1.3
modifier: 496018
reactant: 495927
reactant: 495940
product: 495966
product: 495979
reversible: false
name: N4-Acetylaminobutanal:NAD+ oxidoreductase [cytosol]
type: Reaction
fast: false
product: 495992
reactant: 495953

367743
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

335935
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

559278
stoichiometry: 1.0
species: 321163
type: SpeciesReference

370407
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

514803
stoichiometry: 1.0
species: 328660
type: SpeciesReference

529143
stoichiometry: 1.0
species: 321200
type: SpeciesReference

537614
stoichiometry: 1.0
species: 351285
type: SpeciesReference

R1322 p
product: 462261
is part of: http://identifiers.org/ec-code/1.2.1.3
name: 4-Trimethylammoniobutanal:NAD+ 1-oxidoreductase; [peroxisome]
type: Reaction
product: 462237
is: SBO:0000176
reversible: false
reactant: 462213
product: 462249
fast: false
reactant: 462201
is: R03283
modifier: 462273
reactant: 462225

470851
stoichiometry: 1.0
species: 322159
type: SpeciesReference

507486
stoichiometry: 1.0
species: 321200
type: SpeciesReference

503059
stoichiometry: 1.0
species: 353457
type: SpeciesReference

429971
stoichiometry: 1.0
species: 321686
type: SpeciesReference

519210
stoichiometry: 1.0
species: 321540
type: SpeciesReference

370515
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

522328
stoichiometry: 1.0
species: 325089
type: SpeciesReference

431590
stoichiometry: 1.0
species: 330853
type: SpeciesReference

339843
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

562758
stoichiometry: 1.0
species: 333788
type: SpeciesReference

539126
stoichiometry: 1.0
species: 321163
type: SpeciesReference

506646
stoichiometry: 1.0
species: 325582
type: SpeciesReference

543465
stoichiometry: 1.0
species: 339588
type: SpeciesReference

489796
stoichiometry: 1.0
species: 321722
type: SpeciesReference

R1576 e
reversible: true
type: Reaction
fast: false
modifier: 482082
product: 482070
reactant: 482046
is: R04452
is part of: http://identifiers.org/ec-code/3.1.1.47
name: 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase [extracellular]
reactant: 482034
product: 482058
is: SBO:0000176

511782
stoichiometry: 1.0
species: 321175
type: SpeciesReference

384482
stoichiometry: 1.0
species: 321323
type: SpeciesReference

358388
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

559386
stoichiometry: 1.0
species: 330174
type: SpeciesReference

349905
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

R1291 m
reactant: 460018
product: 460066
is: R03157
reactant: 460042
product: 460078
modifier: 460090
reactant: 460030
fast: false
name: [mitochondria]
type: Reaction
reversible: true
is part of: http://identifiers.org/ec-code/3.1.2.4
product: 460054
is: SBO:0000176

496460
stoichiometry: 1.0
species: 345584
type: SpeciesReference

445578
stoichiometry: 1.0
species: 325077
type: SpeciesReference

524238
stoichiometry: 1.0
species: 327496
type: SpeciesReference

367024
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

336223
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

459838
stoichiometry: 1.0
species: 330089
type: SpeciesReference

333524
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

482286
stoichiometry: 1.0
species: 323537
type: SpeciesReference

326701
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

462729
stoichiometry: 1.0
species: 322453
type: SpeciesReference

524533
stoichiometry: 1.0
species: 321187
type: SpeciesReference

462249
stoichiometry: 1.0
species: 325137
type: SpeciesReference

391597
stoichiometry: 1.0
species: 325125
type: SpeciesReference

570098
stoichiometry: 2.0
species: 336451
type: SpeciesReference

330272
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

528075
stoichiometry: 1.0
species: 325089
type: SpeciesReference

R2740 ec
reversible: true
type: Reaction
product: 570566
product: 570554
is: SBO:0000185
name: Transport [plasma membrane]
reactant: 570542
fast: false
modifier: 570578
reactant: 570530

346615
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

508842
stoichiometry: 1.0
species: 348237
type: SpeciesReference

324229
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

374390
stoichiometry: 1.0
species: 326262
type: SpeciesReference

R158 cp
product: 377703
reactant: 377691
is: SBO:0000185
fast: false
reversible: false
name: Transport of Indole-3-acetaldehyde [peroxisomal membrane]
type: Reaction

331916
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

537506
stoichiometry: 1.0
species: 347205
type: SpeciesReference

474319
stoichiometry: 1.0
species: 350265
type: SpeciesReference

523157
stoichiometry: 1.0
species: 321686
type: SpeciesReference

426263
stoichiometry: 1.0
species: 321163
type: SpeciesReference

403535
stoichiometry: 1.0
species: 321383
type: SpeciesReference

365299
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

367899
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

335827
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1144 r
reactant: 448518
modifier: 448614
fast: false
is: R02501
is part of: http://identifiers.org/ec-code/1.14.14.1
modifier: 448590
product: 448554
reactant: 448530
modifier: 448626
reactant: 448542
modifier: 448638
type: Reaction
is: SBO:0000176
product: 448578
name: Aromatase [endoplasmic reticulum membrane]
reversible: true
product: 448566
modifier: 448602

534818
stoichiometry: 1.0
species: 341528
type: SpeciesReference

337075
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

398704
stoichiometry: 1.0
species: 322904
type: SpeciesReference

466065
stoichiometry: 1.0
species: 322710
type: SpeciesReference

321734
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialintermembranespace
type: Species

416317
stoichiometry: 1.0
species: 327112
type: SpeciesReference

461085
stoichiometry: 1.0
species: 321274
type: SpeciesReference

359876
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

540314
stoichiometry: 1.0
species: 321698
type: SpeciesReference

461637
stoichiometry: 1.0
species: 325161
type: SpeciesReference

353253
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

492820
stoichiometry: 1.0
species: 322061
type: SpeciesReference

485537
stoichiometry: 1.0
species: 342391
type: SpeciesReference

375770
stoichiometry: 1.0
species: 339576
type: SpeciesReference

438148
stoichiometry: 1.0
species: 330841
type: SpeciesReference

555619
stoichiometry: 1.0
species: 324498
type: SpeciesReference

523805
stoichiometry: 1.0
species: 321163
type: SpeciesReference

536954
stoichiometry: 1.0
species: 321625
type: SpeciesReference

434998
stoichiometry: 1.0
species: 321540
type: SpeciesReference

391669
stoichiometry: 1.0
species: 321927
type: SpeciesReference

365587
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R321 g
modifier: 388094
reactant: 388010
reactant: 388022
is part of: http://identifiers.org/ec-code/6.3.1.2
modifier: 388070
product: 388034
fast: false
is: R00253
modifier: 388082
product: 388058
is: SBO:0000176
reversible: true
name: L-Glutamate:ammonia ligase (ADP-forming) [Golgi]
product: 388046
reactant: 387998
type: Reaction

489472
stoichiometry: 1.0
species: 325077
type: SpeciesReference

467229
stoichiometry: 1.0
species: 321783
type: SpeciesReference

557803
stoichiometry: 1.0
species: 321274
type: SpeciesReference

351045
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

456370
stoichiometry: 1.0
species: 321163
type: SpeciesReference

459250
stoichiometry: 1.0
species: 321625
type: SpeciesReference

431890
stoichiometry: 1.0
species: 321927
type: SpeciesReference

511626
stoichiometry: 1.0
species: 348393
type: SpeciesReference

463737
stoichiometry: 1.0
species: 336319
type: SpeciesReference

344084
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

372747
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

398249
stoichiometry: 1.0
species: 324606
type: SpeciesReference

R2351 m
is: SBO:0000176
modifier: 546680
is: R08759
reversible: true
type: Reaction
name: [mitochondrial inner membrane]
product: 546668
fast: false
reactant: 546656
is part of: http://identifiers.org/ec-code/1.14.13.15
modifier: 546692

R1317 c
fast: false
product: 461793
is part of: http://identifiers.org/ec-code/4.1.1.36
is: SBO:0000176
name: N-[(R)-4'-Phosphopantothenoyl]-L-cysteine carboxy-lyase [cytosol]
modifier: 461805
product: 461781
reactant: 461769
type: Reaction
reversible: false
is: R03269

333668
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

R1176 c
is: SBO:0000176
type: Reaction
fast: false
reactant: 451037
product: 451061
is: R02577
reactant: 451025
product: 451049
product: 451073
is part of: http://identifiers.org/ec-code/1.1.1.21
modifier: 451085
reversible: true
name: Propane-1,2-diol:NAD+ 1-oxidoreductase [cytosol]

R2111 c
is: SBO:0000176
reactant: 526527
type: Reaction
reversible: false
fast: false
product: 526575
is: R07492
name: DWF5 (DWARF 5); sterol delta7 reductase [endoplasmic reticulum membrane]
reactant: 526539
modifier: 526587
reactant: 526551
product: 526563
is part of: http://identifiers.org/ec-code/1.3.1.21

373419
stoichiometry: 1.0
species: 324980
type: SpeciesReference

502423
stoichiometry: 1.0
species: 328348
type: SpeciesReference

546584
stoichiometry: 1.0
species: 352329
type: SpeciesReference

373575
stoichiometry: 0.0
species: 328120
type: SpeciesReference

R2155 e
product: 529623
modifier: 529635
name: [plasma membrane]
is: SBO:0000176
reactant: 529587
product: 529611
reactant: 529599
type: Reaction
fast: false
is: R07818
reversible: true
is part of: http://identifiers.org/ec-code/3.2.1.31

508614
stoichiometry: 1.0
species: 338423
type: SpeciesReference

460258
stoichiometry: 1.0
species: 336691
type: SpeciesReference

371379
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

359648
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

505279
stoichiometry: 1.0
species: 324011
type: SpeciesReference

470623
stoichiometry: 1.0
species: 338641
type: SpeciesReference

352425
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R2050 c
is: R07109
reactant: 521989
is part of: http://identifiers.org/ec-code/3.3.2.10
fast: false
reversible: true
modifier: 522026
type: Reaction
name: 11,12-EET hydrolase [cytosol]
product: 522014
is: SBO:0000176
reactant: 522001

332420
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

574213
stoichiometry: 1.0
species: 322159
type: SpeciesReference

471475
stoichiometry: 1.0
species: 342122
type: SpeciesReference

R334 m
product: 389102
reactant: 389090
reversible: true
type: Reaction
fast: false
product: 389138
product: 389114
reactant: 389078
product: 389126
is: R00267
name: Isocitrate:NADP+ oxidoreductase (decarboxylating) [mitochondria]
is: SBO:0000176
is part of: http://identifiers.org/ec-code/1.1.1.42
modifier: 389150

479286
stoichiometry: 1.0
species: 340369
type: SpeciesReference

420696
stoichiometry: 1.0
species: 321212
type: SpeciesReference

323273
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

489232
stoichiometry: 1.0
species: 321528
type: SpeciesReference

568742
stoichiometry: 1.0
species: 327604
type: SpeciesReference

560598
stoichiometry: 1.0
species: 324473
type: SpeciesReference

525479
stoichiometry: 1.0
species: 341383
type: SpeciesReference

R1968 c
modifier: 512863
product: 512802
reactant: 512778
modifier: 512923
modifier: 512911
modifier: 512814
is: SBO:0000176
fast: false
is part of: http://identifiers.org/ec-code/2.5.1.18
type: Reaction
modifier: 512839
modifier: 512827
modifier: 512875
modifier: 512899
modifier: 512887
reversible: false
is: R07026
modifier: 512851
reactant: 512790
name: 1-nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming) [cytosol]

R1222 m
fast: false
is: R02765
is part of: http://identifiers.org/ec-code/5.1.99.1
name: Methylmalonyl-CoA epimerase [mitochondria]
product: 454415
reactant: 454403
type: Reaction
modifier: 454427
reversible: true
is: SBO:0000176

464493
stoichiometry: 1.0
species: 341261
type: SpeciesReference

481974
stoichiometry: 1.0
species: 321163
type: SpeciesReference

345452
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1024 c
product: 439063
is: SBO:0000176
reversible: true
type: Reaction
is part of: http://identifiers.org/ec-code/2.7.4.9
modifier: 439087
product: 439075
reactant: 439039
reactant: 439051
is: R02098
name: ATP:dUMP phosphotransferase [cytosol]
fast: false

332576
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

492556
stoichiometry: 1.0
species: 322942
type: SpeciesReference

nuclearmembrane
is: GO:0031965
is: SBO:0000290
constant: true
size: NaN
spatial dimensions: 3.0
name: nuclear membrane
type: Compartment

419304
stoichiometry: 1.0
species: 322207
type: SpeciesReference

432202
stoichiometry: 1.0
species: 326310
type: SpeciesReference

495836
stoichiometry: 1.0
species: 345440
type: SpeciesReference

R237 c
is: SBO:0000176
is: R00086
product: 381627
reversible: false
modifier: 381663
reactant: 381615
name: vesicle-fusing ATPase [endoplasmic reticulum membrane]
product: 381639
fast: false
type: Reaction
modifier: 381651
is part of: http://identifiers.org/ec-code/3.6.4.6
reactant: 381603

475038
stoichiometry: 1.0
species: 346016
type: SpeciesReference

515343
stoichiometry: 1.0
species: 321540
type: SpeciesReference

509718
stoichiometry: 1.0
species: 348669
type: SpeciesReference

533655
stoichiometry: 1.0
species: 322159
type: SpeciesReference

R568 m
is: SBO:0000176
modifier: 406498
reactant: 406462
reversible: false
type: Reaction
is part of: http://identifiers.org/ec-code/1.3.99.3
is: R00924
fast: false
product: 406486
product: 406474
reactant: 406450
name: Propanoyl-CoA:(acceptor) 2,3-oxidoreductase [mitochondria]

545624
stoichiometry: 1.0
species: 322904
type: SpeciesReference

421728
stoichiometry: 1.0
species: 339346
type: SpeciesReference

529299
stoichiometry: 1.0
species: 324253
type: SpeciesReference

376671
stoichiometry: 1.0
species: 322365
type: SpeciesReference

575701
stoichiometry: 1.0
species: 324498
type: SpeciesReference

424068
stoichiometry: 1.0
species: 321467
type: SpeciesReference

562062
stoichiometry: 1.0
species: 330853
type: SpeciesReference

366796
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2308 r
modifier: 542822
is part of: http://identifiers.org/ec-code/1.14.14.1
reversible: true
product: 542774
modifier: 542834
modifier: 542786
modifier: 542798
name: [endoplasmic reticulum membrane]
is: SBO:0000176
fast: false
type: Reaction
reactant: 542762
is: R08343
modifier: 542810

512130
stoichiometry: 1.0
species: 323998
type: SpeciesReference

543896
stoichiometry: 1.0
species: 331073
type: SpeciesReference

420480
stoichiometry: 1.0
species: 327496
type: SpeciesReference

329475
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

453167
stoichiometry: 1.0
species: 333416
type: SpeciesReference

475374
stoichiometry: 1.0
species: 322428
type: SpeciesReference

489161
stoichiometry: 1.0
species: 325125
type: SpeciesReference

345668
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

363859
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R622 m
type: Reaction
product: 410301
reversible: true
is: SBO:0000176
is part of: http://identifiers.org/ec-code/1.1.99.1
name: choline:acceptor 1-oxidoreductase [mitochondria]
reactant: 410265
modifier: 410313
fast: false
is: R01025
reactant: 410277
product: 410289

352317
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

429827
stoichiometry: 1.0
species: 329475
type: SpeciesReference

400895
stoichiometry: 1.0
species: 321515
type: SpeciesReference

564363
stoichiometry: 1.0
species: 331856
type: SpeciesReference

321515
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

462885
stoichiometry: 1.0
species: 321662
type: SpeciesReference

407746
stoichiometry: 1.0
species: 324510
type: SpeciesReference

570422
stoichiometry: 1.0
species: 331327
type: SpeciesReference

362515
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

361555
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

370731
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

431674
stoichiometry: 1.0
species: 329646
type: SpeciesReference

342776
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R2442 cp
product: 553963
reactant: 553951
is: SBO:0000185
fast: false
reversible: true
name: Transport [peroxisomal membrane]
type: Reaction

478662
stoichiometry: 1.0
species: 325607
type: SpeciesReference

R2628 mc
name: Transport [mitochondrial membrane]
product: 564771
modifier: 564795
reactant: 564759
is: SBO:0000185
type: Reaction
reactant: 564747
fast: false
product: 564783
reversible: false

484433
stoichiometry: 1.0
species: 321515
type: SpeciesReference

425915
stoichiometry: 1.0
species: 328744
type: SpeciesReference

430919
stoichiometry: 1.0
species: 321431
type: SpeciesReference

539270
stoichiometry: 1.0
species: 325077
type: SpeciesReference

339624
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

415945
stoichiometry: 1.0
species: 321274
type: SpeciesReference

414996
stoichiometry: 1.0
species: 342607
type: SpeciesReference

331206
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

509934
stoichiometry: 1.0
species: 321540
type: SpeciesReference

486197
stoichiometry: 1.0
species: 321431
type: SpeciesReference

533871
stoichiometry: 1.0
species: 321163
type: SpeciesReference

499747
stoichiometry: 1.0
species: 336175
type: SpeciesReference

530919
stoichiometry: 1.0
species: 321431
type: SpeciesReference

419976
stoichiometry: 1.0
species: 327640
type: SpeciesReference

384050
stoichiometry: 1.0
species: 325900
type: SpeciesReference

415489
stoichiometry: 1.0
species: 326956
type: SpeciesReference

430703
stoichiometry: 1.0
species: 326057
type: SpeciesReference

R2049 c
product: 521965
name: 14,15-EET hydrolase [cytosol]
reversible: true
modifier: 521977
reactant: 521941
is: SBO:0000176
reactant: 521953
is part of: http://identifiers.org/ec-code/3.3.2.10
fast: false
is: R07108
type: Reaction

R2307 c
modifier: 542750
modifier: 542726
modifier: 542714
reactant: 542678
modifier: 542738
is part of: http://identifiers.org/ec-code/1.14.14.1
name: [endoplasmic reticulum membrane]
product: 542690
fast: false
type: Reaction
reversible: true
is: SBO:0000176
is: R08343
modifier: 542702

329696
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

364927
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

359180
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

518344
stoichiometry: 1.0
species: 321698
type: SpeciesReference

519600
stoichiometry: 1.0
species: 349425
type: SpeciesReference

575449
stoichiometry: 1.0
species: 324510
type: SpeciesReference

489017
stoichiometry: 1.0
species: 325137
type: SpeciesReference

438739
stoichiometry: 1.0
species: 330925
type: SpeciesReference

567254
stoichiometry: 1.0
species: 328240
type: SpeciesReference

353109
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

550460
stoichiometry: 1.0
species: 325089
type: SpeciesReference

466281
stoichiometry: 1.0
species: 321977
type: SpeciesReference

397877
stoichiometry: 1.0
species: 321879
type: SpeciesReference

401483
stoichiometry: 1.0
species: 325342
type: SpeciesReference

R2322 r
is: SBO:0000176
name: 11-cis-retinol: NADP+ oxidoreductase [endoplasmic reticulum]
product: 544004
reactant: 543980
reversible: true
product: 544016
fast: false
is: R08380
product: 543992
type: Reaction
reactant: 543968

461781
stoichiometry: 1.0
species: 322061
type: SpeciesReference

452531
stoichiometry: 1.0
species: 321212
type: SpeciesReference

539810
stoichiometry: 1.0
species: 346941
type: SpeciesReference

534710
stoichiometry: 1.0
species: 351753
type: SpeciesReference

419820
stoichiometry: 1.0
species: 321163
type: SpeciesReference

379491
stoichiometry: 1.0
species: 345632
type: SpeciesReference

R151 ce
product: 377535
reactant: 377523
is: SBO:0000185
fast: false
reversible: false
name: Transport of L-Cystine [plasma membrane]
type: Reaction

518236
stoichiometry: 1.0
species: 321163
type: SpeciesReference

353685
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

R390 p
product: 393013
is: SBO:0000176
fast: false
reversible: true
is: R00391
product: 393001
modifier: 393025
name: Acyl-CoA:acetyl-CoA C-acyltransferase [peroxisome]
is part of: http://identifiers.org/ec-code/2.3.1.16
reactant: 392977
reactant: 392989
type: Reaction

367240
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialinnermembrane
type: Species

394573
stoichiometry: 1.0
species: 327364
type: SpeciesReference

R37 nc
product: 374798
reactant: 374786
is: SBO:0000185
fast: false
reversible: false
name: Transport of dGDP [nuclear membrane]
type: Reaction

406222
stoichiometry: 1.0
species: 321528
type: SpeciesReference

483353
stoichiometry: 1.0
species: 341760
type: SpeciesReference

563978
stoichiometry: 1.0
species: 331880
type: SpeciesReference

325330
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

383798
stoichiometry: 1.0
species: 321323
type: SpeciesReference

455914
stoichiometry: 1.0
species: 321323
type: SpeciesReference

394789
stoichiometry: 1.0
species: 336775
type: SpeciesReference

347169
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

476526
stoichiometry: 1.0
species: 325125
type: SpeciesReference

386810
stoichiometry: 1.0
species: 321540
type: SpeciesReference

R2887 rc
product: 578232
product: 578220
reactant: 578208
reactant: 578196
is: SBO:0000185
fast: false
reversible: true
name: Transport [endoplasmic reticulum membrane]
type: Reaction

R557 c
is: SBO:0000176
reversible: true
type: Reaction
name: L-cysteine:2-oxoglutarate aminotransferase [cytosol]
modifier: 405646
product: 405634
fast: false
is: R00896
reactant: 405610
is part of: http://identifiers.org/ec-code/2.6.1.1
reactant: 405598
product: 405622

528651
stoichiometry: 1.0
species: 350709
type: SpeciesReference

498919
stoichiometry: 1.0
species: 321323
type: SpeciesReference

R722 c
reactant: 417072
product: 417144
is: SBO:0000176
reversible: false
type: Reaction
reactant: 417084
fast: false
reactant: 417060
product: 417132
name: Xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming) [cytosol]
is: R01231
is part of: http://identifiers.org/ec-code/6.3.5.2
reactant: 417096
product: 417120
product: 417108
modifier: 417156

555775
stoichiometry: 1.0
species: 324546
type: SpeciesReference

R1862 g
modifier: 504487
is part of: http://identifiers.org/ec-code/3.2.1.113
reactant: 504427
is: SBO:0000176
reversible: true
type: Reaction
name: glycoside hydrolase family 47 protein [Golgi membrane]
fast: false
reactant: 504439
modifier: 504475
is: R05982
product: 504463
product: 504451

374079
stoichiometry: 1.0
species: 324715
type: SpeciesReference

368727
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

R2152 l
name: [lysosome]
product: 529431
reversible: true
is: R07814
is part of: http://identifiers.org/ec-code/3.10.1.1
type: Reaction
reactant: 529395
fast: false
reactant: 529407
is: SBO:0000176
product: 529419
modifier: 529443

411705
stoichiometry: 1.0
species: 321187
type: SpeciesReference

362371
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

543014
stoichiometry: 1.0
species: 321163
type: SpeciesReference

493828
stoichiometry: 1.0
species: 328744
type: SpeciesReference

383414
stoichiometry: 1.0
species: 321347
type: SpeciesReference

477702
stoichiometry: 1.0
species: 322856
type: SpeciesReference

446010
stoichiometry: 2.0
species: 321163
type: SpeciesReference

R136 ce
product: 377175
reactant: 377163
is: SBO:0000185
fast: false
reversible: false
name: Transport of Nicotinamide [plasma membrane]
type: Reaction

471319
stoichiometry: 1.0
species: 336619
type: SpeciesReference

558726
stoichiometry: 1.0
species: 321783
type: SpeciesReference

470406
stoichiometry: 1.0
species: 327256
type: SpeciesReference

R1285 m
is: SBO:0000176
modifier: 459610
reactant: 459562
fast: false
reversible: true
product: 459586
is part of: http://identifiers.org/ec-code/1.2.1.31
product: 459598
type: Reaction
name: L-2-Aminoadipate-6-semialdehyde:NAD+ 6-oxidoreductase [mitochondria]
reactant: 459538
product: 459574
is: R03102
reactant: 459550

387098
stoichiometry: 1.0
species: 321855
type: SpeciesReference

R2503 cm
product: 557419
reactant: 557407
is: SBO:0000185
fast: false
reversible: false
name: Transport [mitochondrial membrane]
type: Reaction

R2158 l
type: Reaction
modifier: 529827
is part of: http://identifiers.org/ec-code/3.1.6.13
reversible: true
fast: false
reactant: 529791
product: 529815
is: R07821
product: 529803
name: L-iduronate-2-sulfate 2-sulfohydrolase [lysosome]
reactant: 529779
is: SBO:0000176

369903
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

R1500 r
product: 476442
reactant: 476406
is: SBO:0000176
product: 476454
name: Imidazole acetaldehyde:NAD+ oxidoreductase [endoplasmic reticulum]
modifier: 476466
type: Reaction
fast: false
product: 476430
reactant: 476394
reactant: 476418
is part of: http://identifiers.org/ec-code/1.2.1.3
reversible: false
is: R04065

363751
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

564927
stoichiometry: 1.0
species: 321819
type: SpeciesReference

467385
stoichiometry: 1.0
species: 321163
type: SpeciesReference

519717
stoichiometry: 1.0
species: 348465
type: SpeciesReference

353997
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

350241
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

351381
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

513093
stoichiometry: 1.0
species: 348861
type: SpeciesReference

R2448 cr
modifier: 554131
product: 554119
reactant: 554107
is: SBO:0000185
fast: false
reversible: true
name: Transport [endoplasmic reticulum membrane]
type: Reaction

372891
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

429143
stoichiometry: 1.0
species: 333536
type: SpeciesReference

R2685 lc
product: 567818
reactant: 567806
is: SBO:0000185
fast: false
reversible: false
name: Transport [lysosomal membrane]
type: Reaction

R529 c
type: Reaction
product: 403727
is: SBO:0000176
fast: false
is part of: http://identifiers.org/ec-code/3.5.99.6
is: R00765
reactant: 403691
modifier: 403739
modifier: 403751
reversible: true
name: D-glucosamine-6-phosphate aminohydrolase (ketol isomerizing); [cytosol]
reactant: 403703
product: 403715

502855
stoichiometry: 1.0
species: 353421
type: SpeciesReference

376454
stoichiometry: 1.0
species: 338910
type: SpeciesReference

481758
stoichiometry: 1.0
species: 325125
type: SpeciesReference

R1143 c
product: 448446
product: 448422
is: R02501
modifier: 448458
product: 448434
fast: false
reactant: 448410
is part of: http://identifiers.org/ec-code/1.14.14.1
modifier: 448482
is: SBO:0000176
modifier: 448494
reversible: true
modifier: 448470
type: Reaction
reactant: 448386
modifier: 448506
reactant: 448398
name: Aromatase [endoplasmic reticulum membrane]

554815
stoichiometry: 2.0
species: 325077
type: SpeciesReference

377499
stoichiometry: 1.0
species: 332072
type: SpeciesReference

379335
stoichiometry: 1.0
species: 321686
type: SpeciesReference

525259
stoichiometry: 1.0
species: 328180
type: SpeciesReference

467961
stoichiometry: 3.0
species: 321613
type: SpeciesReference

423240
stoichiometry: 1.0
species: 330624
type: SpeciesReference

415789
stoichiometry: 1.0
species: 322710
type: SpeciesReference

429035
stoichiometry: 1.0
species: 333320
type: SpeciesReference

R2708 ec
fast: false
name: Transport [plasma membrane]
product: 569234
type: Reaction
reversible: true
product: 569246
modifier: 569258
product: 569222
reactant: 569210
is: SBO:0000185
reactant: 569198
reactant: 569186

498619
stoichiometry: 1.0
species: 345368
type: SpeciesReference

338970
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

368859
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

556411
stoichiometry: 1.0
species: 347721
type: SpeciesReference

546368
stoichiometry: 1.0
species: 321540
type: SpeciesReference

533223
stoichiometry: 1.0
species: 321163
type: SpeciesReference

449418
stoichiometry: 1.0
species: 324764
type: SpeciesReference

544844
stoichiometry: 1.0
species: 321686
type: SpeciesReference

553171
stoichiometry: 1.0
species: 336439
type: SpeciesReference

414105
stoichiometry: 1.0
species: 326859
type: SpeciesReference

404770
stoichiometry: 1.0
species: 321783
type: SpeciesReference

323839
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

567038
stoichiometry: 2.0
species: 336439
type: SpeciesReference

522544
stoichiometry: 1.0
species: 349845
type: SpeciesReference

349377
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

377283
stoichiometry: 1.0
species: 328959
type: SpeciesReference

R714 c
reversible: true
product: 416437
is: R01220
modifier: 416461
is part of: http://identifiers.org/ec-code/1.5.1.5
fast: false
reactant: 416413
is: SBO:0000176
reactant: 416425
product: 416449
name: 5,10-methylenetetrahydrofolate:NADP+ oxidoreductase [cytosol]
type: Reaction

572101
stoichiometry: 1.0
species: 326481
type: SpeciesReference

555031
stoichiometry: 1.0
species: 322904
type: SpeciesReference

463629
stoichiometry: 1.0
species: 335875
type: SpeciesReference

523001
stoichiometry: 1.0
species: 349917
type: SpeciesReference

R1314 c
modifier: 461601
is part of: http://identifiers.org/ec-code/2.7.1.11
is: SBO:0000176
type: Reaction
is: R03239
product: 461589
name: ITP:D-Tagatose 6-phosphate 1-phosphotransferase [cytosol]
product: 461577
modifier: 461625
reactant: 461553
modifier: 461613
reversible: true
fast: false
reactant: 461565

380463
stoichiometry: 1.0
species: 321323
type: SpeciesReference

420204
stoichiometry: 1.0
species: 327496
type: SpeciesReference

470515
stoichiometry: 1.0
species: 322183
type: SpeciesReference

383870
stoichiometry: 1.0
species: 331784
type: SpeciesReference

546476
stoichiometry: 1.0
species: 352245
type: SpeciesReference

564819
stoichiometry: 1.0
species: 331808
type: SpeciesReference

442159
stoichiometry: 1.0
species: 321175
type: SpeciesReference

544244
stoichiometry: 1.0
species: 321163
type: SpeciesReference

533115
stoichiometry: 1.0
species: 350553
type: SpeciesReference

453635
stoichiometry: 1.0
species: 321613
type: SpeciesReference

R973 i
is part of: http://identifiers.org/ec-code/2.1.4.1
name: L-Arginine:4-aminobutanoate amidinotransferase [mitochondrial intermembrane space]
modifier: 435394
reactant: 435346
is: SBO:0000176
reversible: true
is: R01989
reactant: 435358
fast: false
type: Reaction
product: 435370
product: 435382

R2654 ce
product: 566186
product: 566174
reactant: 566162
reactant: 566150
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

491068
stoichiometry: 1.0
species: 343938
type: SpeciesReference

529875
stoichiometry: 1.0
species: 353913
type: SpeciesReference

563549
stoichiometry: 1.0
species: 331868
type: SpeciesReference

505974
stoichiometry: 1.0
species: 353121
type: SpeciesReference

375146
stoichiometry: 1.0
species: 333440
type: SpeciesReference

R2714 ec
product: 569474
product: 569462
reactant: 569450
reactant: 569438
is: SBO:0000185
fast: false
reversible: false
name: Transport [plasma membrane]
type: Reaction

329190
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

337459
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

379791
stoichiometry: 1.0
species: 321795
type: SpeciesReference

394633
stoichiometry: 1.0
species: 335036
type: SpeciesReference

427379
stoichiometry: 1.0
species: 339600
type: SpeciesReference

467853
stoichiometry: 1.0
species: 321163
type: SpeciesReference

R68 ec
product: 375542
reactant: 375530
is: SBO:0000185
fast: false
reversible: false
name: Transport of Xanthosine [plasma membrane]
type: Reaction

R2849 ec
is: SBO:0000185
modifier: 576073
fast: false
product: 576037
name: Transport [plasma membrane]
reactant: 576025
product: 576049
modifier: 576061
type: Reaction
reactant: 576013
reversible: false

477810
stoichiometry: 1.0
species: 322904
type: SpeciesReference

R1106 r
reactant: 445146
reactant: 445134
product: 445182
modifier: 445254
product: 445170
modifier: 445206
is part of: http://identifiers.org/ec-code/1.14.14.1
reactant: 445122
product: 445194
type: Reaction
is: SBO:0000176
modifier: 445230
reactant: 445158
fast: false
is: R02354
modifier: 445242
name: [endoplasmic reticulum membrane]
reversible: true
modifier: 445218

325209
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

329370
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

502915
stoichiometry: 1.0
species: 326615
type: SpeciesReference

R1139 c
reversible: false
product: 448110
is part of: http://identifiers.org/ec-code/2.7.1.35
reactant: 448074
fast: false
modifier: 448134
product: 448098
name: ATP:pyridoxal 5'-phosphotransferase [cytosol]
is: R02493
modifier: 448122
is: SBO:0000176
type: Reaction
reactant: 448086

481602
stoichiometry: 1.0
species: 334592
type: SpeciesReference

496317
stoichiometry: 1.0
species: 339140
type: SpeciesReference

517528
stoichiometry: 1.0
species: 349209
type: SpeciesReference

457078
stoichiometry: 1.0
species: 338798
type: SpeciesReference

375086
stoichiometry: 1.0
species: 332984
type: SpeciesReference

R1105 c
modifier: 445062
reactant: 445014
fast: false
reactant: 444990
product: 445026
modifier: 445110
reactant: 445002
name: [endoplasmic reticulum membrane]
product: 445050
is: R02354
reactant: 444978
is part of: http://identifiers.org/ec-code/1.14.14.1
reversible: true
modifier: 445098
type: Reaction
product: 445038
modifier: 445086
modifier: 445074
is: SBO:0000176

388286
stoichiometry: 1.0
species: 334400
type: SpeciesReference

389138
stoichiometry: 1.0
species: 325125
type: SpeciesReference

338861
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

447390
stoichiometry: 1.0
species: 335324
type: SpeciesReference

533763
stoichiometry: 1.0
species: 346663
type: SpeciesReference

486089
stoichiometry: 1.0
species: 342728
type: SpeciesReference

359048
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

384374
stoichiometry: 1.0
species: 322304
type: SpeciesReference

382071
stoichiometry: 1.0
species: 321479
type: SpeciesReference

357524
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

346508
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

350133
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

563130
stoichiometry: 1.0
species: 333788
type: SpeciesReference

349485
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

372315
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

R2432 cm
reactant: 553339
modifier: 553387
name: Transport [mitochondrial membrane]
product: 553363
reactant: 553351
is: SBO:0000185
type: Reaction
fast: false
product: 553375
reversible: true

482178
stoichiometry: 1.0
species: 341515
type: SpeciesReference

332828
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

376226
stoichiometry: 1.0
species: 346929
type: SpeciesReference

366640
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

397325
stoichiometry: 1.0
species: 321323
type: SpeciesReference

516150
stoichiometry: 1.0
species: 349173
type: SpeciesReference

474463
stoichiometry: 1.0
species: 343660
type: SpeciesReference

341808
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

475482
stoichiometry: 1.0
species: 342367
type: SpeciesReference

407818
stoichiometry: 1.0
species: 324522
type: SpeciesReference

525369
stoichiometry: 1.0
species: 329919
type: SpeciesReference

362623
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R1790 c
modifier: 499375
is: SBO:0000176
reversible: true
is: R05703
name: lanosterol D24-reductase [endoplasmic reticulum membrane]
product: 499363
reactant: 499327
product: 499339
reactant: 499315
is part of: http://identifiers.org/ec-code/1.3.1.72
fast: false
product: 499351
type: Reaction

370623
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

575557
stoichiometry: 1.0
species: 336439
type: SpeciesReference

417084
stoichiometry: 1.0
species: 324473
type: SpeciesReference

446442
stoichiometry: 1.0
species: 321187
type: SpeciesReference

340431
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

426719
stoichiometry: 1.0
species: 322232
type: SpeciesReference

358496
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R756 e
is: SBO:0000176
fast: false
type: Reaction
modifier: 420012
is: R01315
modifier: 420000
product: 419976
reactant: 419964
modifier: 420036
reactant: 419952
reversible: true
modifier: 420024
modifier: 420048
name: Phosphatidylcholine 2-acylhydrolase [extracellular]
product: 419988
is part of: http://identifiers.org/ec-code/3.1.1.4

384722
stoichiometry: 1.0
species: 321187
type: SpeciesReference

400115
stoichiometry: 1.0
species: 325113
type: SpeciesReference

R1438 p
reversible: false
is: R03719
name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase; [peroxisome]
is part of: http://identifiers.org/ec-code/2.3.1.176
product: 471523
fast: false
modifier: 471547
reactant: 471499
product: 471535
type: Reaction
reactant: 471511
is: SBO:0000176

376839
stoichiometry: 1.0
species: 324655
type: SpeciesReference

450389
stoichiometry: 1.0
species: 330406
type: SpeciesReference

454882
stoichiometry: 1.0
species: 323113
type: SpeciesReference

412041
stoichiometry: 1.0
species: 324338
type: SpeciesReference

435202
stoichiometry: 1.0
species: 330382
type: SpeciesReference

336667
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

478182
stoichiometry: 1.0
species: 341515
type: SpeciesReference

467445
stoichiometry: 1.0
species: 322415
type: SpeciesReference

563432
stoichiometry: 1.0
species: 333800
type: SpeciesReference

343102
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

423540
stoichiometry: 1.0
species: 321200
type: SpeciesReference

R2864 cm
product: 576817
reactant: 576805
is: SBO:0000185
fast: false
reversible: true
name: Transport [mitochondrial membrane]
type: Reaction

414810
stoichiometry: 1.0
species: 326944
type: SpeciesReference

413289
stoichiometry: 1.0
species: 321383
type: SpeciesReference

493264
stoichiometry: 1.0
species: 344708
type: SpeciesReference

326081
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

326142
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

452687
stoichiometry: 1.0
species: 337555
type: SpeciesReference

R861 m
reactant: 426995
is part of: http://identifiers.org/ec-code/2.7.4.14
reactant: 426983
type: Reaction
reversible: false
product: 427007
is: SBO:0000176
product: 427019
fast: false
is: R01665
modifier: 427031
name: ATP:dCMP phosphotransferase [mitochondria]

347721
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

392305
stoichiometry: 1.0
species: 323489
type: SpeciesReference

331315
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

475842
stoichiometry: 1.0
species: 329488
type: SpeciesReference

453359
stoichiometry: 1.0
species: 333416
type: SpeciesReference

478878
stoichiometry: 1.0
species: 321323
type: SpeciesReference

336079
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

365143
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

423696
stoichiometry: 1.0
species: 321783
type: SpeciesReference

326298
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

410541
stoichiometry: 1.0
species: 326214
type: SpeciesReference

329044
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

482393
stoichiometry: 1.0
species: 323549
type: SpeciesReference

R238 c
is: R00089
fast: false
name: ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) [plasma membrane]
modifier: 381819
type: Reaction
modifier: 381711
product: 381687
modifier: 381735
modifier: 381771
modifier: 381759
modifier: 381723
modifier: 381843
is part of: http://identifiers.org/ec-code/4.6.1.1
modifier: 381807
modifier: 381795
reversible: false
product: 381699
modifier: 381747
modifier: 381831
is: SBO:0000176
reactant: 381675
modifier: 381783

R431 c
is: R00548
reactant: 396137
reactant: 396149
reversible: false
product: 396161
name: riboflavin-5-phosphate phosphohydrolase (acid optimum) [cytosol]
modifier: 396209
fast: false
product: 396173
modifier: 396197
is: SBO:0000176
modifier: 396185
type: Reaction
is part of: http://identifiers.org/ec-code/3.1.3.2

438847
stoichiometry: 1.0
species: 331832
type: SpeciesReference

328911
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

376526
stoichiometry: 1.0
species: 345032
type: SpeciesReference

549764
stoichiometry: 2.0
species: 325077
type: SpeciesReference

R2203 n
reversible: false
fast: false
product: 532947
type: Reaction
modifier: 532971
is part of: http://identifiers.org/ec-code/3.1.2.2
is: R08178
reactant: 532935
product: 532959
is: SBO:0000176
name: acyl-CoA thioesterase family protein [nucleus]
reactant: 532923

R1531 c
modifier: 478806
product: 478794
reversible: true
reactant: 478746
name: (R)-4'-Phosphopantothenate:L-cysteine ligase [cytosol]
is: R04231
reactant: 478758
product: 478770
fast: false
is part of: http://identifiers.org/ec-code/6.3.2.5
reactant: 478734
type: Reaction
product: 478782
is: SBO:0000176

386966
stoichiometry: 1.0
species: 322061
type: SpeciesReference

428327
stoichiometry: 1.0
species: 321175
type: SpeciesReference

R1637 m
product: 486941
type: Reaction
is: R04747
modifier: 486953
reactant: 486917
name: Hexanoyl-CoA:acetyl-CoA C-acyltransferase [mitochondrial inner membrane]
product: 486929
fast: false
is part of: http://identifiers.org/ec-code/2.3.1.16
is: SBO:0000176
reactant: 486905
reversible: true

333080
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

407518
stoichiometry: 1.0
species: 347553
type: SpeciesReference

415333
stoichiometry: 1.0
species: 335671
type: SpeciesReference

383642
stoichiometry: 1.0
species: 322085
type: SpeciesReference

350865
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

359768
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2124 m
modifier: 527583
type: Reaction
product: 527559
product: 527547
reactant: 527535
name: 2-oxoisovalerate dehydrogenase, putative / 3-methyl-2-oxobutanoate dehydrogenase, putative / branched-chain alpha-keto acid dehydrogenase E1 alpha subunit, putative [mitochondria]
modifier: 527571
is: R07604
is part of: http://identifiers.org/ec-code/1.2.4.4
reactant: 527523
is: SBO:0000176
fast: false
reversible: false

364459
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

R1356 c
modifier: 464889
reactant: 464781
modifier: 464877
product: 464829
product: 464853
name: omega-3 fatty acid desaturase, chloroplast (FAD7) (FADD) [endoplasmic reticulum membrane]
modifier: 464913
product: 464841
is part of: http://identifiers.org/ec-code/1.14.14.1
modifier: 464901
reactant: 464817
is: R03408
reversible: false
fast: false
reactant: 464805
type: Reaction
modifier: 464865
is: SBO:0000176
reactant: 464793

442387
stoichiometry: 1.0
species: 331472
type: SpeciesReference

510114
stoichiometry: 1.0
species: 334304
type: SpeciesReference

R2491 ce
product: 556543
fast: false
reactant: 556519
reactant: 556507
type: Reaction
name: Transport [plasma membrane]
modifier: 556555
is: SBO:0000185
product: 556531
reversible: false
modifier: 556567

399634
stoichiometry: 1.0
species: 322904
type: SpeciesReference

R1178 c
is part of: http://identifiers.org/ec-code/1.11.1.7
reversible: false
product: 451193
is: SBO:0000176
type: Reaction
is: R02596
modifier: 451205
fast: false
name: Donor:hydrogen-peroxide oxidoreductase [cytosol]
reactant: 451181

455806
stoichiometry: 1.0
species: 334064
type: SpeciesReference

R2311 c
reactant: 543038
name: didemethylcitalopram:oxygen oxidoreductase(deaminating)(flavin-containing) [mitochondrial outer membrane]
is: R08348
product: 543074
type: Reaction
product: 543062
is part of: http://identifiers.org/ec-code/1.4.3.4
modifier: 543086
fast: false
reactant: 543014
is: SBO:0000176
reactant: 543026
product: 543050
reversible: true

430859
stoichiometry: 1.0
species: 323113
type: SpeciesReference

354776
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

342884
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

335719
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

401375
stoichiometry: 1.0
species: 321515
type: SpeciesReference

406378
stoichiometry: 1.0
species: 325682
type: SpeciesReference

R1965 c
name: 1-nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming) [cytosol]
reactant: 512478
reactant: 512490
modifier: 512598
modifier: 512586
reversible: false
type: Reaction
fast: false
modifier: 512622
modifier: 512610
product: 512502
is: SBO:0000176
is part of: http://identifiers.org/ec-code/2.5.1.18
modifier: 512514
modifier: 512550
modifier: 512538
modifier: 512526
is: R07025
modifier: 512574
modifier: 512562

468980
stoichiometry: 1.0
species: 339965
type: SpeciesReference

397985
stoichiometry: 1.0
species: 324534
type: SpeciesReference

321407
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

555379
stoichiometry: 1.0
species: 324498
type: SpeciesReference

323393
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

453047
stoichiometry: 1.0
species: 321686
type: SpeciesReference

R1554 c
reversible: true
product: 480522
reactant: 480486
modifier: 480546
type: Reaction
name: D-myo-Inositol-3,4-bisphosphate 4-phosphohydrolase [cytosol]
modifier: 480534
product: 480510
fast: false
is: R04372
is part of: http://identifiers.org/ec-code/3.1.3.66
is: SBO:0000176
reactant: 480498

345788
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

415621
stoichiometry: 1.0
species: 326956
type: SpeciesReference

R2515 ce
name: Transport [plasma membrane]
reactant: 558175
is: SBO:0000185
product: 558211
reactant: 558199
product: 558223
modifier: 558259
product: 558235
reactant: 558187
fast: false
product: 558247
type: Reaction
reversible: true

R1389 m
is: SBO:0000176
is part of: http://identifiers.org/ec-code/1.1.99.2
product: 467469
reactant: 467457
reversible: true
type: Reaction
name: 2-Hydroxyglutarate:(acceptor) 2-oxidoreductase [mitochondrial inner membrane]
reactant: 467445
product: 467481
modifier: 467493
fast: false
is: R03534

R107 mc
product: 376478
reactant: 376466
is: SBO:0000185
fast: false
reversible: false
name: Transport of Phosphatidylserine [mitochondrial membrane]
type: Reaction

471331
stoichiometry: 1.0
species: 337375
type: SpeciesReference

481986
stoichiometry: 1.0
species: 341407
type: SpeciesReference

367336
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

421020
stoichiometry: 1.0
species: 327640
type: SpeciesReference

500035
stoichiometry: 1.0
species: 330137
type: SpeciesReference

R2863 cl
product: 576793
reactant: 576781
is: SBO:0000185
fast: false
reversible: true
name: Transport [lysosomal membrane]
type: Reaction

R418 c
name: ATP:adenylylsulfate 3'-phosphotransferase [cytosol]
reactant: 395141
is part of: http://identifiers.org/ec-code/2.7.1.25
product: 395177
product: 395165
modifier: 395201
reactant: 395153
is: R00509
reversible: true
is: SBO:0000176
modifier: 395213
fast: false
type: Reaction
modifier: 395189

572989
stoichiometry: 2.0
species: 321163
type: SpeciesReference

391226
stoichiometry: 1.0
species: 321163
type: SpeciesReference

460114
stoichiometry: 1.0
species: 334940
type: SpeciesReference

384950
stoichiometry: 1.0
species: 321879
type: SpeciesReference

464697
stoichiometry: 1.0
species: 321879
type: SpeciesReference

351489
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

558510
stoichiometry: 1.0
species: 326347
type: SpeciesReference

R2787 ce
product: 572617
modifier: 572653
is: SBO:0000185
type: Reaction
product: 572605
reactant: 572545
reactant: 572581
product: 572629
reactant: 572569
product: 572593
name: Transport [plasma membrane]
modifier: 572641
reversible: true
reactant: 572557
fast: false

433906
stoichiometry: 1.0
species: 323766
type: SpeciesReference

323974
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

529179
stoichiometry: 1.0
species: 353745
type: SpeciesReference

499867
stoichiometry: 1.0
species: 341345
type: SpeciesReference

394429
stoichiometry: 1.0
species: 321686
type: SpeciesReference

481770
stoichiometry: 1.0
species: 345596
type: SpeciesReference

346831
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

431494
stoichiometry: 1.0
species: 321783
type: SpeciesReference

R864 e
reactant: 427187
product: 427211
reversible: false
modifier: 427223
is part of: http://identifiers.org/ec-code/3.2.1.108
is: SBO:0000176
name: Lactose galactohydrolase [plasma membrane]
type: Reaction
fast: false
product: 427199
is: R01678
reactant: 427175

522448
stoichiometry: 1.0
species: 325137
type: SpeciesReference

434566
stoichiometry: 1.0
species: 330260
type: SpeciesReference

R1034 c
is part of: http://identifiers.org/ec-code/2.4.1.1
reactant: 439711
fast: false
name: 1,4-alpha-D-Glucan:orthophosphate alpha-D-glucosyltransferase [cytosol]
modifier: 439759
reversible: false
reactant: 439699
type: Reaction
is: R02111
modifier: 439771
product: 439723
product: 439735
modifier: 439747
is: SBO:0000176

338958
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

515247
stoichiometry: 1.0
species: 321175
type: SpeciesReference

384806
stoichiometry: 1.0
species: 321187
type: SpeciesReference

525271
stoichiometry: 1.0
species: 350097
type: SpeciesReference

391166
stoichiometry: 1.0
species: 321879
type: SpeciesReference

506214
stoichiometry: 1.0
species: 343764
type: SpeciesReference

475254
stoichiometry: 1.0
species: 321600
type: SpeciesReference

481830
stoichiometry: 1.0
species: 321588
type: SpeciesReference

361519
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

476310
stoichiometry: 1.0
species: 321383
type: SpeciesReference

345572
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

R1133 r
modifier: 447678
is part of: http://identifiers.org/ec-code/2.4.1.17
product: 447594
reversible: true
name: UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific) [endoplasmic reticulum membrane]
reactant: 447570
modifier: 447618
modifier: 447666
product: 447606
fast: false
is: R02478
modifier: 447642
is: SBO:0000176
modifier: 447702
modifier: 447690
modifier: 447654
modifier: 447630
reactant: 447582
type: Reaction

400991
stoichiometry: 1.0
species: 322856
type: SpeciesReference

453791
stoichiometry: 1.0
species: 335623
type: SpeciesReference

387014
stoichiometry: 1.0
species: 322097
type: SpeciesReference

352329
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

470743
stoichiometry: 1.0
species: 328132
type: SpeciesReference

520926
stoichiometry: 1.0
species: 349653
type: SpeciesReference

515968
stoichiometry: 1.0
species: 321163
type: SpeciesReference

489376
stoichiometry: 1.0
species: 343477
type: SpeciesReference

R463 m
reactant: 398536
fast: false
reactant: 398548
name: ATP:thiamin-phosphate phosphotransferase [mitochondria]
product: 398572
is: SBO:0000176
is: R00617
product: 398560
type: Reaction
reversible: true

434830
stoichiometry: 1.0
species: 321650
type: SpeciesReference

528315
stoichiometry: 1.0
species: 345044
type: SpeciesReference

533559
stoichiometry: 1.0
species: 328660
type: SpeciesReference

470959
stoichiometry: 1.0
species: 340221
type: SpeciesReference

512346
stoichiometry: 1.0
species: 348909
type: SpeciesReference

492988
stoichiometry: 1.0
species: 327724
type: SpeciesReference

447126
stoichiometry: 1.0
species: 322820
type: SpeciesReference

R2380 n
product: 548888
reactant: 548864
type: Reaction
reactant: 548852
is: R09254
name: L-tyrosine:pyruvate aminotransferase [nucleus]
fast: false
product: 548876
reversible: true
is: SBO:0000176

R2785 pc
product: 572509
reactant: 572497
is: SBO:0000185
fast: false
reversible: false
name: Transport [peroxisomal membrane]
type: Reaction

371235
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

R567 m
name: beta-alanine:2-oxoglutarate aminotransferase [mitochondria]
reactant: 406390
is: R00908
product: 406414
reactant: 406402
product: 406426
fast: false
is: SBO:0000176
type: Reaction
modifier: 406438
is part of: http://identifiers.org/ec-code/2.6.1.19
reversible: true

375290
stoichiometry: 1.0
species: 335144
type: SpeciesReference

469912
stoichiometry: 1.0
species: 337615
type: SpeciesReference

368607
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

344180
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

416473
stoichiometry: 1.0
species: 321431
type: SpeciesReference

388058
stoichiometry: 1.0
species: 324461
type: SpeciesReference

R1069 c
is: SBO:0000176
modifier: 442411
name: (5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13- dienoate E-isomerase [endoplasmic reticulum membrane]
is part of: http://identifiers.org/ec-code/5.3.99.3
reversible: true
is: R02265
modifier: 442423
reactant: 442387
type: Reaction
fast: false
product: 442399

R966 p
reactant: 434758
modifier: 434818
is: SBO:0000176
product: 434794
is part of: http://identifiers.org/ec-code/1.1.1.35
is: R01975
fast: false
reactant: 434746
product: 434770
modifier: 434806
product: 434782
type: Reaction
name: (S)-3-Hydroxybutanoyl-CoA:NAD+ oxidoreductase [peroxisome]
reversible: true

379623
stoichiometry: 1.0
species: 321710
type: SpeciesReference

389366
stoichiometry: 1.0
species: 322917
type: SpeciesReference

R2100 m
reactant: 525808
is: SBO:0000176
modifier: 525856
is: R07411
product: 525832
reversible: false
reactant: 525796
reactant: 525820
type: Reaction
fast: false
product: 525844
name: protoheme IX farnesyltransferase [mitochondrial inner membrane]

322013
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

346711
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

390278
stoichiometry: 2.0
species: 325125
type: SpeciesReference

321637
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

557923
stoichiometry: 1.0
species: 321274
type: SpeciesReference

473503
stoichiometry: 1.0
species: 345956
type: SpeciesReference

559182
stoichiometry: 1.0
species: 321783
type: SpeciesReference

578856
stoichiometry: 2.0
species: 336439
type: SpeciesReference

365683
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

528171
stoichiometry: 1.0
species: 325125
type: SpeciesReference

459958
stoichiometry: 1.0
species: 322244
type: SpeciesReference

423312
stoichiometry: 1.0
species: 339358
type: SpeciesReference

362035
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

424416
stoichiometry: 1.0
species: 321613
type: SpeciesReference

332144
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

324326
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

336103
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

375890
stoichiometry: 1.0
species: 343712
type: SpeciesReference

372987
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

R609 c
reactant: 409498
product: 409510
name: L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming) [cytosol]
modifier: 409546
reactant: 409486
product: 409534
is part of: http://identifiers.org/ec-code/4.4.1.1
is: SBO:0000176
product: 409522
type: Reaction
is: R01001
fast: false
reversible: false

503611
stoichiometry: 1.0
species: 322292
type: SpeciesReference

R1209 c
modifier: 453551
reversible: false
product: 453527
modifier: 453623
is part of: http://identifiers.org/ec-code/3.1.3.46
name: D-Fructose-2,6-bisphosphate 2-phosphohydrolase [cytosol]
product: 453515
fast: false
reactant: 453503
reactant: 453491
modifier: 453563
type: Reaction
modifier: 453587
is: SBO:0000176
modifier: 453575
modifier: 453599
modifier: 453539
modifier: 453611
is: R02731

563874
stoichiometry: 1.0
species: 321819
type: SpeciesReference

463977
stoichiometry: 1.0
species: 321274
type: SpeciesReference

467673
stoichiometry: 1.0
species: 321407
type: SpeciesReference

470249
stoichiometry: 1.0
species: 322159
type: SpeciesReference

524741
stoichiometry: 1.0
species: 332720
type: SpeciesReference

523709
stoichiometry: 1.0
species: 332528
type: SpeciesReference

R492 m
name: 3-Oxopropanoate:NAD+ oxidoreductase (decarboxylating, CoA-acetylating) [mitochondria]
product: 400715
type: Reaction
product: 400727
modifier: 400751
reactant: 400679
product: 400703
reactant: 400667
reactant: 400691
reversible: false
is: R00705
fast: false
is part of: http://identifiers.org/ec-code/1.2.1.18
is: SBO:0000176
product: 400739

544016
stoichiometry: 1.0
species: 337927
type: SpeciesReference

468812
stoichiometry: 1.0
species: 337963
type: SpeciesReference

367731
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

R2873 ec
reactant: 577429
product: 577477
type: Reaction
modifier: 577513
reversible: false
name: Transport [plasma membrane]
fast: false
modifier: 577501
reactant: 577441
product: 577465
product: 577489
reactant: 577453
is: SBO:0000185

537626
stoichiometry: 1.0
species: 351309
type: SpeciesReference

R2396 c
is: SBO:0000176
fast: false
reactant: 549956
reversible: true
is: R09395
modifier: 549992
type: Reaction
name: [cytosol]
reactant: 549968
product: 549980

507498
stoichiometry: 1.0
species: 348081
type: SpeciesReference

562878
stoichiometry: 1.0
species: 330865
type: SpeciesReference

335947
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

524676
stoichiometry: 1.0
species: 332720
type: SpeciesReference

513615
stoichiometry: 1.0
species: 325089
type: SpeciesReference

390062
stoichiometry: 1.0
species: 324023
type: SpeciesReference

462129
stoichiometry: 1.0
species: 325125
type: SpeciesReference

533439
stoichiometry: 1.0
species: 339733
type: SpeciesReference

330370
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

576517
stoichiometry: 1.0
species: 321927
type: SpeciesReference

R980 c
is: SBO:0000176
name: 2'-Deoxyadenosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase [cytosol]
modifier: 435826
is part of: http://identifiers.org/ec-code/1.17.4.1
fast: false
reactant: 435754
product: 435790
reversible: false
modifier: 435814
is: R02017
product: 435778
modifier: 435838
product: 435802
type: Reaction
reactant: 435766

549272
stoichiometry: 1.0
species: 324131
type: SpeciesReference

R2072 c
reactant: 523877
product: 523889
type: Reaction
is: SBO:0000176
is: R07299
reversible: true
name: 1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase [lysosomal membrane]
fast: false
reactant: 523865
modifier: 523913
is part of: http://identifiers.org/ec-code/3.1.3.66
product: 523901

346340
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

367120
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

377835
stoichiometry: 1.0
species: 335623
type: SpeciesReference

400271
stoichiometry: 1.0
species: 322880
type: SpeciesReference

435934
stoichiometry: 1.0
species: 322304
type: SpeciesReference

324655
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

R2595 cm
fast: false
name: Transport [mitochondrial membrane]
product: 562722
reactant: 562710
reversible: false
reactant: 562698
product: 562734
type: Reaction
modifier: 562746
is: SBO:0000185

484721
stoichiometry: 1.0
species: 343725
type: SpeciesReference

491884
stoichiometry: 1.0
species: 321613
type: SpeciesReference

496174
stoichiometry: 1.0
species: 325125
type: SpeciesReference

575461
stoichiometry: 1.0
species: 327388
type: SpeciesReference

427391
stoichiometry: 1.0
species: 322134
type: SpeciesReference

406582
stoichiometry: 1.0
species: 345740
type: SpeciesReference

543345
stoichiometry: 1.0
species: 349953
type: SpeciesReference

506742
stoichiometry: 1.0
species: 353793
type: SpeciesReference

414249
stoichiometry: 1.0
species: 321163
type: SpeciesReference

R2803 mc
reactant: 573481
product: 573505
modifier: 573553
fast: false
reversible: false
reactant: 573469
type: Reaction
product: 573541
product: 573529
name: Transport [mitochondrial membrane]
is: SBO:0000185
reactant: 573493
product: 573517

575149
stoichiometry: 1.0
species: 326384
type: SpeciesReference

489676
stoichiometry: 1.0
species: 343621
type: SpeciesReference

347025
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

559074
stoichiometry: 1.0
species: 326166
type: SpeciesReference

359996
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

338011
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

475158
stoichiometry: 1.0
species: 321662
type: SpeciesReference

R2686 ec
product: 567890
reactant: 567830
product: 567866
is: SBO:0000185
name: Transport [plasma membrane]
modifier: 567902
fast: false
type: Reaction
reversible: false
reactant: 567854
product: 567878
reactant: 567842

467001
stoichiometry: 1.0
species: 331928
type: SpeciesReference

360188
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

498931
stoichiometry: 1.0
species: 322856
type: SpeciesReference

447942
stoichiometry: 1.0
species: 332408
type: SpeciesReference

490072
stoichiometry: 1.0
species: 322490
type: SpeciesReference

354620
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

433054
stoichiometry: 1.0
species: 321163
type: SpeciesReference

410337
stoichiometry: 1.0
species: 337723
type: SpeciesReference

507270
stoichiometry: 1.0
species: 348069
type: SpeciesReference

537518
stoichiometry: 1.0
species: 321175
type: SpeciesReference

R1661 c
modifier: 488645
is part of: http://identifiers.org/ec-code/5.3.3.5
is: SBO:0000176
reversible: false
name: delta8,24-Cholestadien-3beta-ol delta7-delta8-isomerase [endoplasmic reticulum membrane]
reactant: 488621
product: 488633
is: R04804
type: Reaction
fast: false

523145
stoichiometry: 1.0
species: 321540
type: SpeciesReference

403547
stoichiometry: 1.0
species: 331952
type: SpeciesReference

365287
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

367887
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

335839
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

426275
stoichiometry: 1.0
species: 331640
type: SpeciesReference

324217
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

389978
stoichiometry: 1.0
species: 324860
type: SpeciesReference

R2419 c
type: Reaction
modifier: 552391
name: [endoplasmic reticulum membrane]
product: 552379
reversible: true
is: R09441
product: 552355
product: 552367
modifier: 552439
modifier: 552427
is: SBO:0000176
reactant: 552343
reactant: 552319
reactant: 552331
is part of: http://identifiers.org/ec-code/1.14.14.1
modifier: 552415
modifier: 552403
reactant: 552307
fast: false

331904
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

416329
stoichiometry: 2.0
species: 327016
type: SpeciesReference

359888
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

430931
stoichiometry: 1.0
species: 332504
type: SpeciesReference

468968
stoichiometry: 1.0
species: 322503
type: SpeciesReference

366508
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

324920
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

521589
stoichiometry: 1.0
species: 349785
type: SpeciesReference

R2510 ce
product: 557947
name: Transport [plasma membrane]
reactant: 557935
reactant: 557923
is: SBO:0000185
modifier: 557995
reversible: false
type: Reaction
product: 557959
product: 557983
fast: false
product: 557971
reactant: 557911

322453
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

534806
stoichiometry: 1.0
species: 321383
type: SpeciesReference

337087
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

466077
stoichiometry: 1.0
species: 341093
type: SpeciesReference

321746
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

391657
stoichiometry: 1.0
species: 321819
type: SpeciesReference

523817
stoichiometry: 1.0
species: 347949
type: SpeciesReference

489460
stoichiometry: 1.0
species: 321540
type: SpeciesReference

555607
stoichiometry: 1.0
species: 323585
type: SpeciesReference

434986
stoichiometry: 1.0
species: 332624
type: SpeciesReference

R152 cn
product: 377559
reactant: 377547
is: SBO:0000185
fast: false
reversible: false
name: Transport of Oleoyl-CoA [nuclear membrane]
type: Reaction

407950
stoichiometry: 1.0
species: 325803
type: SpeciesReference

536942
stoichiometry: 1.0
species: 321175
type: SpeciesReference

461649
stoichiometry: 1.0
species: 335288
type: SpeciesReference

353241
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

478890
stoichiometry: 1.0
species: 322856
type: SpeciesReference

528207
stoichiometry: 1.0
species: 331375
type: SpeciesReference

R2638 cm
product: 565383
fast: false
type: Reaction
reactant: 565347
product: 565371
reactant: 565359
name: Transport [mitochondrial membrane]
is: SBO:0000185
modifier: 565395
reversible: false

438136
stoichiometry: 1.0
species: 321855
type: SpeciesReference

485525
stoichiometry: 1.0
species: 321431
type: SpeciesReference

375782
stoichiometry: 1.0
species: 339539
type: SpeciesReference

540326
stoichiometry: 1.0
species: 325089
type: SpeciesReference

511638
stoichiometry: 1.0
species: 321163
type: SpeciesReference

456382
stoichiometry: 1.0
species: 321383
type: SpeciesReference

541706
stoichiometry: 1.0
species: 321698
type: SpeciesReference

365575
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

570650
stoichiometry: 1.0
species: 326992
type: SpeciesReference

336091
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

442867
stoichiometry: 1.0
species: 321879
type: SpeciesReference

467217
stoichiometry: 1.0
species: 336523
type: SpeciesReference

351057
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

557815
stoichiometry: 1.0
species: 321819
type: SpeciesReference

339831
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

411933
stoichiometry: 1.0
species: 327328
type: SpeciesReference

R631 c
product: 410877
is: SBO:0000176
reactant: 410865
is part of: http://identifiers.org/ec-code/5.3.1.6
fast: false
reversible: true
type: Reaction
is: R01056
modifier: 410889
name: D-ribose-5-phosphate aldose-ketose-isomerase [cytosol]

328839
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1840 g
reactant: 502927
product: 502951
reversible: true
product: 502939
is: SBO:0000176
modifier: 502963
reactant: 502915
type: Reaction
is part of: http://identifiers.org/ec-code/2.4.99.4
name: [Golgi membrane]
is: R05957
fast: false
modifier: 502975

429983
stoichiometry: 2.0
species: 325077
type: SpeciesReference

333188
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

423108
stoichiometry: 1.0
species: 340319
type: SpeciesReference

370503
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

R1231 c
reactant: 455038
type: Reaction
product: 455062
reversible: true
name: S-adenosylmethioninamine:spermidine 3-aminopropyltransferase [cytosol]
reactant: 455050
has part: http://identifiers.org/ec-code/2.5.1.22
is: R02869
modifier: 455086
has part: http://identifiers.org/ec-code/2.5.1.16
product: 455074
modifier: 455098
is: SBO:0000176
fast: false

324764
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

R2545 nc
product: 559986
reactant: 559974
is: SBO:0000185
fast: false
reversible: false
name: Transport [nuclear membrane]
type: Reaction

396089
stoichiometry: 1.0
species: 321163
type: SpeciesReference

563274
stoichiometry: 1.0
species: 336571
type: SpeciesReference

355292
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

445470
stoichiometry: 1.0
species: 321625
type: SpeciesReference

543453
stoichiometry: 1.0
species: 336511
type: SpeciesReference

530211
stoichiometry: 1.0
species: 340925
type: SpeciesReference

384494
stoichiometry: 1.0
species: 322352
type: SpeciesReference

511794
stoichiometry: 1.0
species: 321625
type: SpeciesReference

505818
stoichiometry: 1.0
species: 353289
type: SpeciesReference

484877
stoichiometry: 1.0
species: 342969
type: SpeciesReference

333512
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

437583
stoichiometry: 1.0
species: 322159
type: SpeciesReference

372879
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosomalmembrane
type: Species

548600
stoichiometry: 1.0
species: 343115
type: SpeciesReference

367012
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

336211
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

482274
stoichiometry: 1.0
species: 330649
type: SpeciesReference

532539
stoichiometry: 1.0
species: 346520
type: SpeciesReference

475590
stoichiometry: 1.0
species: 322037
type: SpeciesReference

407302
stoichiometry: 1.0
species: 328851
type: SpeciesReference

462237
stoichiometry: 1.0
species: 321528
type: SpeciesReference

474307
stoichiometry: 1.0
species: 338361
type: SpeciesReference

513719
stoichiometry: 1.0
species: 348645
type: SpeciesReference

570086
stoichiometry: 1.0
species: 326907
type: SpeciesReference

R2297 c
modifier: 541910
modifier: 541886
reactant: 541838
product: 541850
is: SBO:0000176
modifier: 541874
modifier: 541898
name: [endoplasmic reticulum membrane]
is: R08318
modifier: 541862
is part of: http://identifiers.org/ec-code/1.14.14.1
type: Reaction
reversible: true
fast: false

346603
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

330260
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

391585
stoichiometry: 1.0
species: 323429
type: SpeciesReference

528063
stoichiometry: 1.0
species: 321552
type: SpeciesReference

R1532 c
reactant: 478818
reactant: 478830
is: R04241
fast: false
name: Tetrahydrofolyl-[Glu](n):L-glutamate gamma-ligase (ADP-forming) [cytosol]
type: Reaction
is part of: http://identifiers.org/ec-code/6.3.2.17
product: 478854
is: SBO:0000176
reversible: true
product: 478842
modifier: 478866

332588
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

515355
stoichiometry: 1.0
species: 321686
type: SpeciesReference

338848
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

525381
stoichiometry: 1.0
species: 339612
type: SpeciesReference

495823
stoichiometry: 1.0
species: 321163
type: SpeciesReference

R2403 p
reactant: 550832
modifier: 550868
is: SBO:0000176
reversible: true
reactant: 550844
is: R09409
product: 550856
name: glutathione-S-transferase [peroxisome]
type: Reaction
is part of: http://identifiers.org/ec-code/2.5.1.18
fast: false

R384 p
is: SBO:0000176
is: R00369
reactant: 392617
reactant: 392629
product: 392641
name: L-Alanine:glyoxylate aminotransferase [peroxisome]
modifier: 392665
product: 392653
is part of: http://identifiers.org/ec-code/2.6.1.44
type: Reaction
reversible: true
fast: false

431039
stoichiometry: 1.0
species: 329606
type: SpeciesReference

529287
stoichiometry: 1.0
species: 354021
type: SpeciesReference

487865
stoichiometry: 1.0
species: 321613
type: SpeciesReference

509706
stoichiometry: 1.0
species: 321613
type: SpeciesReference

346941
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

545612
stoichiometry: 1.0
species: 322013
type: SpeciesReference

329488
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

558666
stoichiometry: 1.0
species: 326335
type: SpeciesReference

533667
stoichiometry: 1.0
species: 322503
type: SpeciesReference

R2065 c
reversible: true
product: 523409
reactant: 523337
reactant: 523349
is part of: http://identifiers.org/ec-code/1.14.13.100
product: 523397
is: R07209
reactant: 523373
product: 523385
modifier: 523421
type: Reaction
fast: false
reactant: 523361
name: cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase(7alpha-hydroxylating) [endoplasmic reticulum membrane]
is: SBO:0000176

541838
stoichiometry: 1.0
species: 351633
type: SpeciesReference

543884
stoichiometry: 1.0
species: 325077
type: SpeciesReference

372603
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

367228
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

562050
stoichiometry: 1.0
species: 336571
type: SpeciesReference

507042
stoichiometry: 1.0
species: 353841
type: SpeciesReference

563118
stoichiometry: 1.0
species: 321323
type: SpeciesReference

517540
stoichiometry: 1.0
species: 349281
type: SpeciesReference

337351
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R228 mc
modifier: 380559
type: Reaction
reactant: 380463
modifier: 380571
modifier: 380607
name: H+-transporting two-sector ATPase [mitochondrial membrane]
fast: false
product: 380487
modifier: 380643
modifier: 380655
modifier: 380691
reversible: false
modifier: 380523
is part of: http://identifiers.org/ec-code/3.6.3.14
modifier: 380679
product: 380511
modifier: 380703
modifier: 380547
is: SBO:0000185
modifier: 380667
reactant: 380451
reactant: 380475
modifier: 380595
modifier: 380727
is: R00086
modifier: 380739
modifier: 380535
modifier: 380715
modifier: 380619
modifier: 380631
product: 380499
modifier: 380583

400883
stoichiometry: 1.0
species: 340720
type: SpeciesReference

453155
stoichiometry: 1.0
species: 321163
type: SpeciesReference

492568
stoichiometry: 1.0
species: 344192
type: SpeciesReference

330999
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

379779
stoichiometry: 1.0
species: 321299
type: SpeciesReference

389210
stoichiometry: 1.0
species: 322917
type: SpeciesReference

376010
stoichiometry: 1.0
species: 344732
type: SpeciesReference

473659
stoichiometry: 1.0
species: 338059
type: SpeciesReference

575881
stoichiometry: 1.0
species: 336439
type: SpeciesReference

507342
stoichiometry: 1.0
species: 321150
type: SpeciesReference

344072
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2225 c
reactant: 534375
reactant: 534363
product: 534399
modifier: 534411
fast: false
is: SBO:0000176
type: Reaction
product: 534387
name: ATP:5-fluorodeoxyuridine 5'-phosphotransferase [cytosol]
is part of: http://identifiers.org/ec-code/2.7.1.21
reversible: false
is: R08233

383858
stoichiometry: 1.0
species: 321347
type: SpeciesReference

372759
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

524895
stoichiometry: 1.0
species: 350109
type: SpeciesReference

352437
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

442255
stoichiometry: 1.0
species: 333332
type: SpeciesReference

373587
stoichiometry: 0.0
species: 338629
type: SpeciesReference

492832
stoichiometry: 1.0
species: 344264
type: SpeciesReference

512454
stoichiometry: 1.0
species: 348993
type: SpeciesReference

323285
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

506322
stoichiometry: 1.0
species: 330137
type: SpeciesReference

489220
stoichiometry: 1.0
species: 343441
type: SpeciesReference

574201
stoichiometry: 1.0
species: 321951
type: SpeciesReference

568754
stoichiometry: 1.0
species: 327616
type: SpeciesReference

R1160 e
reactant: 449837
is: R02541
type: Reaction
reversible: false
is part of: http://identifiers.org/ec-code/3.1.4.12
reactant: 449825
fast: false
modifier: 449897
modifier: 449885
modifier: 449873
name: Sphingomyelin cholinephosphohydrolase [plasma membrane]
product: 449861
product: 449849
is: SBO:0000176

554107
stoichiometry: 1.0
species: 322710
type: SpeciesReference

332432
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

R2202 c
is part of: http://identifiers.org/ec-code/3.1.2.2
product: 532899
modifier: 532911
is: R08178
name: acyl-CoA thioesterase family protein [cytosol]
type: Reaction
fast: false
reactant: 532863
reactant: 532875
is: SBO:0000176
product: 532887
reversible: false

512790
stoichiometry: 1.0
species: 348849
type: SpeciesReference

345464
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

464481
stoichiometry: 1.0
species: 322316
type: SpeciesReference

R76 cm
product: 375734
reactant: 375722
is: SBO:0000185
fast: false
reversible: false
name: Transport of L-Methionyl-tRNA [mitochondrial membrane]
type: Reaction

463725
stoichiometry: 1.0
species: 321200
type: SpeciesReference

498511
stoichiometry: 1.0
species: 322734
type: SpeciesReference

R826 m
is part of: http://identifiers.org/ec-code/2.7.4.3
product: 424655
is: SBO:0000176
name: ATP:dAMP phosphotransferase [mitochondria]
modifier: 424679
reactant: 424631
is: R01547
type: Reaction
reactant: 424643
product: 424667
fast: false
reversible: true

539822
stoichiometry: 1.0
species: 351393
type: SpeciesReference

461793
stoichiometry: 1.0
species: 335360
type: SpeciesReference

R2700 cp
product: 568754
reactant: 568742
is: SBO:0000185
fast: false
reversible: false
name: Transport [peroxisomal membrane]
type: Reaction

R2088 c
product: 525022
fast: false
reversible: true
product: 525009
name: Plasmanylcholine 2-acylhydrolase [cytosol]
modifier: 525047
is part of: http://identifiers.org/ec-code/3.1.1.4
modifier: 525035
is: R07387
reactant: 524996
type: Reaction
is: SBO:0000176
reactant: 524984

419832
stoichiometry: 1.0
species: 327496
type: SpeciesReference

392929
stoichiometry: 1.0
species: 323561
type: SpeciesReference

401495
stoichiometry: 1.0
species: 321528
type: SpeciesReference

397865
stoichiometry: 1.0
species: 334916
type: SpeciesReference

559290
stoichiometry: 1.0
species: 321274
type: SpeciesReference

578700
stoichiometry: 1.0
species: 325365
type: SpeciesReference

345680
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

343319
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

394585
stoichiometry: 1.0
species: 322232
type: SpeciesReference

568190
stoichiometry: 1.0
species: 336451
type: SpeciesReference

432526
stoichiometry: 1.0
species: 329833
type: SpeciesReference

576697
stoichiometry: 1.0
species: 323658
type: SpeciesReference

406210
stoichiometry: 1.0
species: 344456
type: SpeciesReference

430715
stoichiometry: 1.0
species: 329593
type: SpeciesReference

518224
stoichiometry: 1.0
species: 347313
type: SpeciesReference

412749
stoichiometry: 1.0
species: 340406
type: SpeciesReference

353697
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

447234
stoichiometry: 1.0
species: 321248
type: SpeciesReference

489568
stoichiometry: 1.0
species: 321383
type: SpeciesReference

R825 c
is: R01547
modifier: 424619
product: 424572
name: ATP:dAMP phosphotransferase [cytosol]
product: 424560
is part of: http://identifiers.org/ec-code/2.7.4.3
reversible: true
modifier: 424595
type: Reaction
modifier: 424607
fast: false
reactant: 424536
modifier: 424584
is: SBO:0000176
reactant: 424548

476538
stoichiometry: 1.0
species: 338958
type: SpeciesReference

R2484 cr
product: 556243
reactant: 556231
is: SBO:0000185
fast: false
reversible: true
name: Transport [endoplasmic reticulum membrane]
type: Reaction

321528
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

364339
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

374067
stoichiometry: 1.0
species: 324727
type: SpeciesReference

368715
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

411717
stoichiometry: 1.0
species: 343890
type: SpeciesReference

463509
stoichiometry: 1.0
species: 321903
type: SpeciesReference

362383
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

554263
stoichiometry: 1.0
species: 325077
type: SpeciesReference

555763
stoichiometry: 1.0
species: 323585
type: SpeciesReference

R2104 n
is: R07460
product: 526048
is part of: http://identifiers.org/ec-code/2.8.1.7
reversible: false
fast: false
modifier: 526072
reactant: 526024
type: Reaction
is: SBO:0000176
product: 526060
reactant: 526036
name: L-cysteine:[ThiI] sulfurtransferase [nucleus]

R2752 ec
modifier: 571142
modifier: 571130
product: 571118
reactant: 571106
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

R2833 cm
fast: false
is: SBO:0000185
reactant: 574981
name: Transport [mitochondrial membrane]
product: 574993
product: 575005
modifier: 575017
reversible: true
type: Reaction
reactant: 574969

361567
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

570434
stoichiometry: 1.0
species: 336439
type: SpeciesReference

R694 p
product: 415189
name: butanoyl-CoA:acetyl-CoA C-butanoyltransferase [peroxisome]
is: SBO:0000176
modifier: 415201
is part of: http://identifiers.org/ec-code/2.3.1.16
product: 415177
reversible: true
reactant: 415165
reactant: 415153
fast: false
is: R01177
type: Reaction

397469
stoichiometry: 1.0
species: 324860
type: SpeciesReference

407734
stoichiometry: 1.0
species: 327112
type: SpeciesReference

412533
stoichiometry: 1.0
species: 326518
type: SpeciesReference

339612
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

423036
stoichiometry: 1.0
species: 321540
type: SpeciesReference

415933
stoichiometry: 2.0
species: 327016
type: SpeciesReference

425903
stoichiometry: 1.0
species: 324107
type: SpeciesReference

478674
stoichiometry: 1.0
species: 340160
type: SpeciesReference

484445
stoichiometry: 1.0
species: 325125
type: SpeciesReference

342788
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

419988
stoichiometry: 1.0
species: 340925
type: SpeciesReference

435106
stoichiometry: 1.0
species: 325089
type: SpeciesReference

376719
stoichiometry: 1.0
species: 323405
type: SpeciesReference

499759
stoichiometry: 1.0
species: 321843
type: SpeciesReference

331218
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

533883
stoichiometry: 1.0
species: 342281
type: SpeciesReference

R253 c
modifier: 383042
modifier: 383030
type: Reaction
product: 382982
name: ATP:ADP phosphatransferase [cytosol]
fast: false
modifier: 382994
is part of: http://identifiers.org/ec-code/2.7.4.6
reactant: 382958
reversible: true
modifier: 383018
is: R00124
product: 382970
is: SBO:0000176
reactant: 382946
modifier: 383006

362503
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

R2597 mc
modifier: 562866
product: 562854
name: Transport [mitochondrial membrane]
product: 562842
reactant: 562830
reversible: false
fast: false
reactant: 562818
is: SBO:0000185
type: Reaction

567266
stoichiometry: 1.0
species: 325077
type: SpeciesReference

466293
stoichiometry: 1.0
species: 342318
type: SpeciesReference

550472
stoichiometry: 1.0
species: 347085
type: SpeciesReference

R988 m
is: R02030
reversible: true
product: 436510
name: CDP-diacylglycerol:phosphatidylglycerol 3-phosphatidyltransferase [mitochondrial inner membrane]
is: SBO:0000176
fast: false
modifier: 436522
reactant: 436486
product: 436498
reactant: 436474
type: Reaction

R1877 g
name: [Golgi membrane]
product: 505579
modifier: 505591
is: SBO:0000176
reactant: 505555
modifier: 505603
is: R06032
reactant: 505543
is part of: http://identifiers.org/ec-code/2.4.99.8
product: 505567
fast: false
type: Reaction
reversible: true

523925
stoichiometry: 1.0
species: 321686
type: SpeciesReference

359192
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

325438
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

518332
stoichiometry: 1.0
species: 321552
type: SpeciesReference

364939
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

489005
stoichiometry: 1.0
species: 321528
type: SpeciesReference

467973
stoichiometry: 1.0
species: 336799
type: SpeciesReference

533319
stoichiometry: 1.0
species: 346567
type: SpeciesReference

415777
stoichiometry: 1.0
species: 322061
type: SpeciesReference

427235
stoichiometry: 1.0
species: 321200
type: SpeciesReference

383210
stoichiometry: 1.0
species: 321819
type: SpeciesReference

460570
stoichiometry: 1.0
species: 325755
type: SpeciesReference

R1811 r
product: 501019
modifier: 501031
is: SBO:0000176
name: [endoplasmic reticulum membrane]
reversible: true
fast: false
reactant: 500995
type: Reaction
is: R05920
product: 501007
reactant: 500983

429047
stoichiometry: 1.0
species: 321528
type: SpeciesReference

368847
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

449406
stoichiometry: 1.0
species: 321710
type: SpeciesReference

R268 m
reactant: 383918
reversible: true
product: 383990
name: Carbon-dioxide:ammonia ligase (ADP-forming,carbamate-phosphorylating) [mitochondria]
is part of: http://identifiers.org/ec-code/6.3.4.16
product: 383978
product: 383966
reactant: 383954
is: R00149
is: SBO:0000176
reactant: 383930
type: Reaction
modifier: 384002
fast: false
reactant: 383942

478062
stoichiometry: 1.0
species: 341153
type: SpeciesReference

404782
stoichiometry: 1.0
species: 335240
type: SpeciesReference

R1933 p
is: SBO:0000176
name: (S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase [peroxisome]
product: 509250
product: 509262
is part of: http://identifiers.org/ec-code/1.1.1.35
fast: false
reversible: true
modifier: 509274
reactant: 509226
is: R06941
modifier: 509286
reactant: 509214
type: Reaction
product: 509238

556423
stoichiometry: 1.0
species: 321783
type: SpeciesReference

464589
stoichiometry: 1.0
species: 335971
type: SpeciesReference

471907
stoichiometry: 1.0
species: 337651
type: SpeciesReference

544856
stoichiometry: 1.0
species: 325077
type: SpeciesReference

377271
stoichiometry: 1.0
species: 328971
type: SpeciesReference

442039
stoichiometry: 1.0
species: 323549
type: SpeciesReference

R245 p
type: Reaction
modifier: 382323
product: 382299
is: R00103
reactant: 382275
product: 382311
is: SBO:0000176
is part of: http://identifiers.org/ec-code/3.6.1.22
fast: false
reactant: 382287
name: NAD+ phosphohydrolase [peroxisome]
reversible: false

349365
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

408082
stoichiometry: 1.0
species: 321187
type: SpeciesReference

507126
stoichiometry: 1.0
species: 332720
type: SpeciesReference

407110
stoichiometry: 1.0
species: 325755
type: SpeciesReference

R981 n
product: 435898
is part of: http://identifiers.org/ec-code/1.17.4.1
is: SBO:0000176
product: 435874
modifier: 435910
reactant: 435850
fast: false
product: 435886
modifier: 435922
reversible: false
type: Reaction
name: 2'-Deoxyadenosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase [nucleus]
is: R02017
reactant: 435862

R2254 c
is part of: http://identifiers.org/ec-code/1.14.14.1
name: [endoplasmic reticulum membrane]
reversible: true
is: R08268
fast: false
is: SBO:0000176
type: Reaction
product: 537002
modifier: 537014
modifier: 537050
modifier: 537026
reactant: 536990
modifier: 537062
modifier: 537038

558738
stoichiometry: 1.0
species: 321879
type: SpeciesReference

470418
stoichiometry: 1.0
species: 337183
type: SpeciesReference

323827
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

R1393 c
reactant: 467709
reversible: true
is: R03545
modifier: 467769
fast: false
is: SBO:0000176
name: [Golgi membrane]
product: 467757
reactant: 467733
reactant: 467721
product: 467745
type: Reaction

477714
stoichiometry: 1.0
species: 344336
type: SpeciesReference

400547
stoichiometry: 1.0
species: 340025
type: SpeciesReference

568706
stoichiometry: 1.0
species: 333860
type: SpeciesReference

543026
stoichiometry: 1.0
species: 321686
type: SpeciesReference

508782
stoichiometry: 1.0
species: 321187
type: SpeciesReference

363763
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

513081
stoichiometry: 1.0
species: 321175
type: SpeciesReference

398560
stoichiometry: 1.0
species: 321819
type: SpeciesReference

528891
stoichiometry: 1.0
species: 353973
type: SpeciesReference

558882
stoichiometry: 1.0
species: 321163
type: SpeciesReference

350253
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R476 m
product: 399671
is part of: http://identifiers.org/ec-code/2.6.1.13
reversible: true
modifier: 399683
reactant: 399646
fast: false
is: SBO:0000176
product: 399659
is: R00667
reactant: 399634
type: Reaction
name: L-Ornithine:2-oxo-acid aminotransferase [mitochondria]

R1364 c
product: 465513
modifier: 465525
reactant: 465477
fast: false
is: SBO:0000176
name: D-myo-Inositol 1,3,4-trisphosphate 1-phosphohydrolase [cytosol]
product: 465501
is: R03427
is part of: http://identifiers.org/ec-code/3.1.3.57
reversible: false
reactant: 465489
type: Reaction

554803
stoichiometry: 2.0
species: 321879
type: SpeciesReference

383426
stoichiometry: 1.0
species: 322564
type: SpeciesReference

502867
stoichiometry: 1.0
species: 326627
type: SpeciesReference

344492
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

368991
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

379347
stoichiometry: 1.0
species: 337903
type: SpeciesReference

377487
stoichiometry: 1.0
species: 332012
type: SpeciesReference

R764 c
reactant: 420564
modifier: 420588
product: 420576
fast: false
is: R01324
is: SBO:0000176
is part of: http://identifiers.org/ec-code/4.2.1.3
reversible: true
type: Reaction
name: citrate hydroxymutase [cytosol]

353805
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

R124 ce
product: 376887
reactant: 376875
is: SBO:0000185
fast: false
reversible: false
name: Transport of L-Ornithine [plasma membrane]
type: Reaction

376442
stoichiometry: 1.0
species: 338898
type: SpeciesReference

497551
stoichiometry: 1.0
species: 321212
type: SpeciesReference

571801
stoichiometry: 1.0
species: 327316
type: SpeciesReference

481614
stoichiometry: 1.0
species: 341371
type: SpeciesReference

388274
stoichiometry: 1.0
species: 324473
type: SpeciesReference

375074
stoichiometry: 1.0
species: 332996
type: SpeciesReference

457066
stoichiometry: 1.0
species: 321455
type: SpeciesReference

503695
stoichiometry: 1.0
species: 345380
type: SpeciesReference

R2383 g
product: 549080
name: UDP-D-GlcNAc:O-L-fucosylpeptide 3-beta-N-acetyl-D-glucosaminyltransferase [Golgi membrane]
reactant: 549056
is part of: http://identifiers.org/ec-code/2.4.1.222
modifier: 549116
reversible: true
modifier: 549092
fast: false
is: R09296
type: Reaction
reactant: 549044
is: SBO:0000176
product: 549068
modifier: 549104

407002
stoichiometry: 1.0
species: 325755
type: SpeciesReference

502927
stoichiometry: 1.0
species: 346172
type: SpeciesReference

519704
stoichiometry: 1.0
species: 325089
type: SpeciesReference

413181
stoichiometry: 1.0
species: 321163
type: SpeciesReference

350145
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

357512
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialoutermembrane
type: Species

384386
stoichiometry: 1.0
species: 321783
type: SpeciesReference

349473
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

372303
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

424080
stoichiometry: 1.0
species: 325077
type: SpeciesReference

403691
stoichiometry: 1.0
species: 321163
type: SpeciesReference

359036
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

454727
stoichiometry: 1.0
species: 333968
type: SpeciesReference

482166
stoichiometry: 1.0
species: 322820
type: SpeciesReference

361411
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R793 l
reactant: 422412
product: 422460
reactant: 422400
type: Reaction
fast: false
product: 422448
is: R01434
name: L-Valine:NAD+ oxidoreductase(deaminating) [lysosome]
product: 422424
reactant: 422388
reversible: true
product: 422436
is: SBO:0000176

376238
stoichiometry: 1.0
species: 346917
type: SpeciesReference

366652
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

414395
stoichiometry: 1.0
species: 335515
type: SpeciesReference

445698
stoichiometry: 1.0
species: 321552
type: SpeciesReference

412689
stoichiometry: 2.0
species: 325077
type: SpeciesReference

R683 c
modifier: 414421
is: R01159
fast: false
reactant: 414369
name: S-adenosyl-L-methionine:L-histidine N-methyltransferase [cytosol]
reversible: false
modifier: 414434
reactant: 414357
is: SBO:0000176
type: Reaction
product: 414395
product: 414382
modifier: 414408

329383
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

474451
stoichiometry: 2.0
species: 333488
type: SpeciesReference

R1747 r
reversible: false
type: Reaction
product: 496070
fast: false
is: SBO:0000176
reactant: 496031
reactant: 496044
name: N4-Acetylaminobutanal:NAD+ oxidoreductase [endoplasmic reticulum]
is: R05050
product: 496096
modifier: 496109
reactant: 496057
product: 496083
is part of: http://identifiers.org/ec-code/1.2.1.3

383366
stoichiometry: 1.0
species: 321335
type: SpeciesReference

R830 c
modifier: 424991
name: dATP:uridine 5'-phosphotransferase [cytosol]
is: R01549
modifier: 425003
product: 424955
reactant: 424931
is part of: http://identifiers.org/ec-code/2.7.1.48
reactant: 424919
type: Reaction
modifier: 424967
reversible: false
modifier: 424979
product: 424943
fast: false
is: SBO:0000176

475470
stoichiometry: 1.0
species: 322013
type: SpeciesReference

407806
stoichiometry: 1.0
species: 327136
type: SpeciesReference

532695
stoichiometry: 1.0
species: 332276
type: SpeciesReference

R1659 c
product: 488489
type: Reaction
modifier: 488513
product: 488501
reversible: false
reactant: 488477
modifier: 488525
is: R04779
is part of: http://identifiers.org/ec-code/2.7.1.11
reactant: 488465
fast: false
name: ATP:D-fructose-6-phosphate 1-phosphotransferase [plasma membrane]
is: SBO:0000176

R789 c
reactant: 422112
type: Reaction
reversible: true
name: 5,6-Dihydrothymine:NAD+ oxidoreductase [cytosol]
product: 422124
fast: false
is: R01414
product: 422148
is: SBO:0000176
reactant: 422100
product: 422136

380451
stoichiometry: 1.0
species: 321212
type: SpeciesReference

424631
stoichiometry: 1.0
species: 321323
type: SpeciesReference

431278
stoichiometry: 1.0
species: 321698
type: SpeciesReference

492460
stoichiometry: 1.0
species: 344180
type: SpeciesReference

502711
stoichiometry: 1.0
species: 346208
type: SpeciesReference

554959
stoichiometry: 1.0
species: 347757
type: SpeciesReference

R859 e
modifier: 426911
product: 426887
reactant: 426875
reactant: 426863
fast: false
type: Reaction
product: 426899
reversible: false
is part of: http://identifiers.org/ec-code/3.1.3.5
is: R01664
is: SBO:0000176
name: 2'-Deoxycytidine 5'-monophosphate phosphohydrolase [plasma membrane]

R1230 c
is: SBO:0000176
reactant: 454966
is: R02840
modifier: 455026
reactant: 454954
name: Cortisol delta5-delat4-isomerase; [endoplasmic reticulum membrane]
type: Reaction
modifier: 455014
reversible: true
reactant: 454978
fast: false
product: 455002
is part of: http://identifiers.org/ec-code/1.1.1.145
product: 454990

555043
stoichiometry: 1.0
species: 327316
type: SpeciesReference

373431
stoichiometry: 0.0
species: 325197
type: SpeciesReference

564807
stoichiometry: 1.0
species: 321323
type: SpeciesReference

546488
stoichiometry: 1.0
species: 321467
type: SpeciesReference

533103
stoichiometry: 1.0
species: 321163
type: SpeciesReference

556315
stoichiometry: 1.0
species: 322453
type: SpeciesReference

453647
stoichiometry: 1.0
species: 335623
type: SpeciesReference

564212
stoichiometry: 1.0
species: 331832
type: SpeciesReference

470527
stoichiometry: 1.0
species: 322539
type: SpeciesReference

395089
stoichiometry: 1.0
species: 324071
type: SpeciesReference

432418
stoichiometry: 1.0
species: 325888
type: SpeciesReference

375134
stoichiometry: 1.0
species: 333368
type: SpeciesReference

339407
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

333680
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

394645
stoichiometry: 1.0
species: 323273
type: SpeciesReference

496304
stoichiometry: 1.0
species: 325137
type: SpeciesReference

335611
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R1855 g
product: 503947
is: R05975
reversible: true
modifier: 503995
is: SBO:0000176
modifier: 503983
name: [Golgi membrane]
is part of: http://identifiers.org/ec-code/2.4.1.149
type: Reaction
product: 503959
fast: false
reactant: 503935
modifier: 503971
reactant: 503923

525492
stoichiometry: 1.0
species: 321163
type: SpeciesReference

359660
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

491056
stoichiometry: 1.0
species: 321383
type: SpeciesReference

416101
stoichiometry: 1.0
species: 333392
type: SpeciesReference

363871
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

505962
stoichiometry: 1.0
species: 330137
type: SpeciesReference

463401
stoichiometry: 1.0
species: 321879
type: SpeciesReference

493948
stoichiometry: 1.0
species: 321383
type: SpeciesReference

467865
stoichiometry: 1.0
species: 321274
type: SpeciesReference

477822
stoichiometry: 1.0
species: 339819
type: SpeciesReference

R66 pc
product: 375494
reactant: 375482
is: SBO:0000185
fast: false
reversible: false
name: Transport of 4-Trimethylammoniobutanoate [peroxisomal membrane]
type: Reaction

358280
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

329056
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

482381
stoichiometry: 1.0
species: 330649
type: SpeciesReference

438859
stoichiometry: 1.0
species: 332024
type: SpeciesReference

410553
stoichiometry: 1.0
species: 321540
type: SpeciesReference

521277
stoichiometry: 1.0
species: 336403
type: SpeciesReference

549776
stoichiometry: 1.0
species: 352557
type: SpeciesReference

376514
stoichiometry: 1.0
species: 345044
type: SpeciesReference

423684
stoichiometry: 1.0
species: 328276
type: SpeciesReference

R1792 c
is part of: http://identifiers.org/ec-code/1.14.13.70
reactant: 499483
fast: false
reactant: 499495
product: 499531
name: sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving) [endoplasmic reticulum membrane]
type: Reaction
reactant: 499471
modifier: 499555
product: 499507
is: SBO:0000176
product: 499543
reactant: 499459
is: R05731
product: 499519
reversible: true

365131
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

362491
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

550580
stoichiometry: 1.0
species: 323937
type: SpeciesReference

449598
stoichiometry: 1.0
species: 321613
type: SpeciesReference

350853
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

364447
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

510102
stoichiometry: 1.0
species: 325089
type: SpeciesReference

565730
stoichiometry: 1.0
species: 340503
type: SpeciesReference

383630
stoichiometry: 1.0
species: 321187
type: SpeciesReference

410409
stoichiometry: 1.0
species: 321467
type: SpeciesReference

398416
stoichiometry: 1.0
species: 321236
type: SpeciesReference

398993
stoichiometry: 1.0
species: 321479
type: SpeciesReference

R43 ec
product: 374942
reactant: 374930
is: SBO:0000185
fast: false
reversible: false
name: Transport of Methylglyoxal [plasma membrane]
type: Reaction

415345
stoichiometry: 1.0
species: 321867
type: SpeciesReference

R523 c
name: L-tyrosine carboxy-lyase (tyramine-forming) [cytosol]
reversible: false
product: 403295
fast: false
modifier: 403319
type: Reaction
is part of: http://identifiers.org/ec-code/4.1.1.28
reactant: 403283
product: 403307
is: SBO:0000176
is: R00736

386954
stoichiometry: 1.0
species: 323417
type: SpeciesReference

562158
stoichiometry: 1.0
species: 333800
type: SpeciesReference

354788
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

433198
stoichiometry: 1.0
species: 329991
type: SpeciesReference

495940
stoichiometry: 1.0
species: 321383
type: SpeciesReference

342896
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

428471
stoichiometry: 1.0
species: 329265
type: SpeciesReference

502639
stoichiometry: 1.0
species: 326615
type: SpeciesReference

406366
stoichiometry: 1.0
species: 322661
type: SpeciesReference

483497
stoichiometry: 1.0
species: 325077
type: SpeciesReference

401387
stoichiometry: 1.0
species: 323309
type: SpeciesReference

340599
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1286 m
modifier: 459694
fast: false
type: Reaction
product: 459682
reactant: 459634
name: L-2-Aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase [mitochondria]
reversible: true
is: R03103
reactant: 459646
is: SBO:0000176
product: 459658
product: 459670
is part of: http://identifiers.org/ec-code/1.2.1.31
reactant: 459622

555367
stoichiometry: 1.0
species: 326835
type: SpeciesReference

397973
stoichiometry: 1.0
species: 323875
type: SpeciesReference

408694
stoichiometry: 1.0
species: 325972
type: SpeciesReference

426707
stoichiometry: 1.0
species: 328959
type: SpeciesReference

446454
stoichiometry: 1.0
species: 321710
type: SpeciesReference

370611
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2592 mc
type: Reaction
reversible: false
reactant: 562530
modifier: 562566
fast: false
product: 562542
reactant: 562518
product: 562554
name: Transport [mitochondrial membrane]
is: SBO:0000185

362611
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1667 p
is: SBO:0000176
reversible: false
is: R04811
type: Reaction
modifier: 489113
reactant: 489065
product: 489089
is part of: http://identifiers.org/ec-code/2.3.1.176
fast: false
product: 489101
reactant: 489077
name: Propanoyl-CoA:acetyl-CoA C-acyltransferase; [peroxisome]

321419
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

417072
stoichiometry: 1.0
species: 321274
type: SpeciesReference

336655
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2611 mc
reversible: false
reactant: 563692
fast: false
is: SBO:0000185
type: Reaction
reactant: 563679
product: 563705
modifier: 563731
product: 563718
name: Transport [mitochondrial membrane]

R155 cp
product: 377631
reactant: 377619
is: SBO:0000185
fast: false
reversible: false
name: Transport of 3-Hydroxyanthranilate [peroxisomal membrane]
type: Reaction

467457
stoichiometry: 1.0
species: 338726
type: SpeciesReference

400127
stoichiometry: 1.0
species: 327760
type: SpeciesReference

478170
stoichiometry: 1.0
species: 321274
type: SpeciesReference

406426
stoichiometry: 1.0
species: 328696
type: SpeciesReference

384734
stoichiometry: 1.0
species: 324872
type: SpeciesReference

326094
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

412053
stoichiometry: 1.0
species: 326409
type: SpeciesReference

454870
stoichiometry: 1.0
species: 321686
type: SpeciesReference

376827
stoichiometry: 1.0
species: 324630
type: SpeciesReference

533019
stoichiometry: 1.0
species: 346591
type: SpeciesReference

R2099 l
fast: false
type: Reaction
product: 525760
reactant: 525724
product: 525772
reversible: true
is: R07410
name: L-aspartate:NAD+ oxidoreductase (deaminating) [lysosome]
product: 525748
modifier: 525784
is part of: http://identifiers.org/ec-code/1.4.1.21
is: SBO:0000176
reactant: 525736

431158
stoichiometry: 1.0
species: 329606
type: SpeciesReference

353541
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

R573 m
reactant: 406774
modifier: 406822
product: 406810
product: 406798
is: SBO:0000176
name: acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase; [mitochondrial inner membrane]
reactant: 406786
is: R00927
fast: false
is part of: http://identifiers.org/ec-code/2.3.1.16
reversible: false
type: Reaction

332720
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

331327
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

453347
stoichiometry: 1.0
species: 322159
type: SpeciesReference

493252
stoichiometry: 1.0
species: 321187
type: SpeciesReference

326154
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

R2337 m
reactant: 545528
reactant: 545492
product: 545564
is: R08505
reactant: 545504
product: 545540
reversible: true
product: 545552
name: cholesterol 26-hydroxylase [mitochondrial inner membrane]
fast: false
type: Reaction
is part of: http://identifiers.org/ec-code/1.14.13.15
reactant: 545516
modifier: 545576
modifier: 545588
is: SBO:0000176

R1035 e
product: 439807
reactant: 439795
name: Phosphatidylcholine:sterol O-acyltransferase [plasma membrane]
product: 439819
reversible: true
is part of: http://identifiers.org/ec-code/2.3.1.43
type: Reaction
is: SBO:0000176
reactant: 439783
is: R02114
fast: false
modifier: 439831

452675
stoichiometry: 1.0
species: 327640
type: SpeciesReference

503071
stoichiometry: 1.0
species: 324131
type: SpeciesReference

392317
stoichiometry: 2.0
species: 326531
type: SpeciesReference

R665 c
is part of: http://identifiers.org/ec-code/3.1.3.5
modifier: 413097
reactant: 413013
type: Reaction
name: Inosine 5'-monophosphate phosphohydrolase [cytosol]
modifier: 413109
fast: false
is: R01126
reversible: false
product: 413049
modifier: 413061
product: 413037
modifier: 413085
reactant: 413025
modifier: 413073
is: SBO:0000176

406570
stoichiometry: 1.0
species: 322013
type: SpeciesReference

550448
stoichiometry: 1.0
species: 321698
type: SpeciesReference

445446
stoichiometry: 1.0
species: 331940
type: SpeciesReference

353121
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

367156
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

R500 p
is part of: http://identifiers.org/ec-code/1.2.1.3
product: 401495
modifier: 401531
product: 401507
reactant: 401471
reactant: 401459
type: Reaction
reactant: 401483
fast: false
is: SBO:0000176
is: R00710
reversible: true
name: Acetaldehyde:NAD+ oxidoreductase [peroxisome]
product: 401519

322576
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

462117
stoichiometry: 1.0
species: 321515
type: SpeciesReference

390098
stoichiometry: 1.0
species: 333848
type: SpeciesReference

337471
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

442987
stoichiometry: 1.0
species: 333068
type: SpeciesReference

391465
stoichiometry: 1.0
species: 321383
type: SpeciesReference

498943
stoichiometry: 1.0
species: 337027
type: SpeciesReference

447930
stoichiometry: 1.0
species: 322415
type: SpeciesReference

329344
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

R386 m
fast: false
type: Reaction
product: 392761
modifier: 392785
product: 392773
reactant: 392749
reactant: 392737
reversible: true
is: R00372
is: SBO:0000176
name: Glycine:2-oxoglutarate aminotransferase [mitochondria]
is part of: http://identifiers.org/ec-code/2.6.1.44

524105
stoichiometry: 1.0
species: 321163
type: SpeciesReference

456574
stoichiometry: 1.0
species: 345788
type: SpeciesReference

410301
stoichiometry: 1.0
species: 332756
type: SpeciesReference

352593
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

467037
stoichiometry: 1.0
species: 321163
type: SpeciesReference

575113
stoichiometry: 1.0
species: 332012
type: SpeciesReference

R824 c
name: D-Ribulose-5-phosphate 3-epimerase [cytosol]
modifier: 424524
reactant: 424500
product: 424512
fast: false
is part of: http://identifiers.org/ec-code/5.1.3.1
type: Reaction
reversible: true
is: SBO:0000176
is: R01529

445590
stoichiometry: 1.0
species: 331940
type: SpeciesReference

489664
stoichiometry: 1.0
species: 323113
type: SpeciesReference

466197
stoichiometry: 1.0
species: 323537
type: SpeciesReference

506778
stoichiometry: 1.0
species: 353793
type: SpeciesReference

543333
stoichiometry: 1.0
species: 337867
type: SpeciesReference

321600
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

524663
stoichiometry: 1.0
species: 341700
type: SpeciesReference

R143 ce
product: 377343
reactant: 377331
is: SBO:0000185
fast: false
reversible: false
name: Transport of D-Erythrose 4-phosphate [plasma membrane]
type: Reaction

R1884 c
is: R06127
product: 506058
fast: false
product: 506046
reactant: 506022
modifier: 506070
is: SBO:0000176
name: GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase [endoplasmic reticulum membrane]
reactant: 506034
reversible: true
type: Reaction

347181
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

477906
stoichiometry: 1.0
species: 325125
type: SpeciesReference

332132
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

366628
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

365998
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

R52 mc
product: 375158
reactant: 375146
is: SBO:0000185
fast: false
reversible: false
name: Transport of Xanthosine 5'-phosphate [mitochondrial membrane]
type: Reaction

578868
stoichiometry: 1.0
species: 329807
type: SpeciesReference

322049
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

559194
stoichiometry: 1.0
species: 321879
type: SpeciesReference

377907
stoichiometry: 1.0
species: 338313
type: SpeciesReference

346747
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

369471
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

407830
stoichiometry: 1.0
species: 325791
type: SpeciesReference

557935
stoichiometry: 3.0
species: 325658
type: SpeciesReference

R687 m
reversible: true
product: 414694
name: Butanoyl-CoA:(acceptor) 2,3-oxidoreductase; [mitochondria]
product: 414681
is: SBO:0000176
fast: false
modifier: 414707
is: R01171
is part of: http://identifiers.org/ec-code/1.3.8.1
type: Reaction
reactant: 414655
product: 414668
reactant: 414642

523289
stoichiometry: 1.0
species: 321163
type: SpeciesReference

367767
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

399097
stoichiometry: 1.0
species: 325125
type: SpeciesReference

335959
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

496187
stoichiometry: 1.0
species: 339128
type: SpeciesReference

426131
stoichiometry: 1.0
species: 326286
type: SpeciesReference

556591
stoichiometry: 1.0
species: 336451
type: SpeciesReference

398837
stoichiometry: 1.0
species: 325077
type: SpeciesReference

371919
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

432562
stoichiometry: 1.0
species: 321323
type: SpeciesReference

440527
stoichiometry: 1.0
species: 321187
type: SpeciesReference

568178
stoichiometry: 1.0
species: 328132
type: SpeciesReference

408502
stoichiometry: 1.0
species: 329794
type: SpeciesReference

468848
stoichiometry: 1.0
species: 324351
type: SpeciesReference

R1905 c
is: R06516
reversible: false
product: 507306
is: SBO:0000176
fast: false
is part of: http://identifiers.org/ec-code/4.1.2.27
modifier: 507330
reactant: 507294
product: 507318
name: sphingosine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming) [endoplasmic reticulum membrane]
type: Reaction

R2420 r
modifier: 552535
fast: false
reversible: true
type: Reaction
is: SBO:0000176
is: R09441
reactant: 552451
product: 552511
modifier: 552583
reactant: 552463
modifier: 552559
modifier: 552571
is part of: http://identifiers.org/ec-code/1.14.14.1
reactant: 552475
product: 552499
reactant: 552487
name: [endoplasmic reticulum membrane]
product: 552523
modifier: 552547

559254
stoichiometry: 1.0
species: 328108
type: SpeciesReference

544004
stoichiometry: 1.0
species: 325089
type: SpeciesReference

R2717 ec
modifier: 569582
product: 569570
reactant: 569558
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

463989
stoichiometry: 1.0
species: 335899
type: SpeciesReference

467685
stoichiometry: 1.0
species: 346244
type: SpeciesReference

495966
stoichiometry: 1.0
species: 321467
type: SpeciesReference

492952
stoichiometry: 1.0
species: 324143
type: SpeciesReference

489364
stoichiometry: 1.0
species: 325077
type: SpeciesReference

528327
stoichiometry: 1.0
species: 322097
type: SpeciesReference

R2773 ec
product: 572149
reactant: 572125
product: 572161
type: Reaction
fast: false
modifier: 572197
reactant: 572137
name: Transport [plasma membrane]
modifier: 572185
reversible: false
modifier: 572173
is: SBO:0000185

368523
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

398261
stoichiometry: 1.0
species: 321163
type: SpeciesReference

R383 m
is part of: http://identifiers.org/ec-code/2.6.1.44
product: 392581
fast: false
product: 392593
reactant: 392569
reactant: 392557
name: L-Alanine:glyoxylate aminotransferase [mitochondria]
reversible: true
type: Reaction
modifier: 392605
is: SBO:0000176
is: R00369

R1971 r
modifier: 513119
fast: false
is: SBO:0000176
is: R07027
product: 513106
reactant: 513081
name: 1-nitronaphthalene-5,6-oxide hydrolase [endoplasmic reticulum membrane]
type: Reaction
reversible: true
is part of: http://identifiers.org/ec-code/3.3.2.9
reactant: 513093

470211
stoichiometry: 1.0
species: 321274
type: SpeciesReference

434866
stoichiometry: 1.0
species: 325113
type: SpeciesReference

412893
stoichiometry: 1.0
species: 326676
type: SpeciesReference

479154
stoichiometry: 1.0
species: 325077
type: SpeciesReference

574345
stoichiometry: 1.0
species: 325077
type: SpeciesReference

R968 c
modifier: 434950
product: 434938
is: R01978
reactant: 434890
is: SBO:0000176
fast: false
reversible: true
name: acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming) [cytosol]
reactant: 434902
type: Reaction
product: 434926
is part of: http://identifiers.org/ec-code/2.3.3.10
product: 434914

476322
stoichiometry: 1.0
species: 342159
type: SpeciesReference

401915
stoichiometry: 1.0
species: 321212
type: SpeciesReference

388190
stoichiometry: 1.0
species: 324485
type: SpeciesReference

481842
stoichiometry: 1.0
species: 325125
type: SpeciesReference

493528
stoichiometry: 1.0
species: 344768
type: SpeciesReference

345584
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

538454
stoichiometry: 1.0
species: 347493
type: SpeciesReference

R282 c
product: 384950
product: 384962
fast: false
is: R00173
reversible: true
modifier: 384986
modifier: 384974
reactant: 384926
name: pyridoxal-5'-phosphate phosphohydrolase [plasma membrane]
is part of: http://identifiers.org/ec-code/3.1.3.74
reactant: 384938
type: Reaction
is: SBO:0000176

363727
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

336391
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

475242
stoichiometry: 1.0
species: 338713
type: SpeciesReference

537782
stoichiometry: 1.0
species: 321540
type: SpeciesReference

432334
stoichiometry: 1.0
species: 322232
type: SpeciesReference

379659
stoichiometry: 2.0
species: 321187
type: SpeciesReference

473539
stoichiometry: 1.0
species: 338047
type: SpeciesReference

R1274 c
type: Reaction
is part of: http://identifiers.org/ec-code/3.3.2.6
modifier: 458362
reactant: 458326
reversible: false
reactant: 458338
name: (7E,9E,11Z,14Z)-(5S,6S)-5,6-Epoxyicosa-7,9,11,14-tetraenoate hydrolase [cytosol]
is: R03057
product: 458350
is: SBO:0000176
fast: false

496796
stoichiometry: 1.0
species: 321455
type: SpeciesReference

529707
stoichiometry: 1.0
species: 321200
type: SpeciesReference

R1460 p
is part of: http://identifiers.org/ec-code/2.3.1.16
type: Reaction
fast: false
reversible: true
product: 473083
is: R03858
name: Lauroyl-CoA:acetyl-CoA C-acyltransferase [peroxisome]
reactant: 473047
is: SBO:0000176
modifier: 473095
reactant: 473059
product: 473071

R1140 c
reactant: 448158
is: SBO:0000176
product: 448182
fast: false
product: 448170
name: pyridoxamine-5'-phosphate phosphohydrolase [plasma membrane]
is: R02494
modifier: 448206
modifier: 448194
is part of: http://identifiers.org/ec-code/3.1.3.74
reactant: 448146
type: Reaction
reversible: true

371247
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2086 c
is: SBO:0000176
reactant: 524869
is: R07385
type: Reaction
is part of: http://identifiers.org/ec-code/3.1.4.4
reactant: 524857
product: 524882
product: 524895
modifier: 524908
fast: false
reversible: false
name: phospholipase D alpha 2 / PLD alpha 2 (PLDALPHA2) (PLD2) / choline phosphatase 2 [cytosol]

400583
stoichiometry: 1.0
species: 328024
type: SpeciesReference

533523
stoichiometry: 1.0
species: 321236
type: SpeciesReference

323851
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

R2669 ec
name: Transport [plasma membrane]
reactant: 566942
product: 566966
reactant: 566954
is: SBO:0000185
fast: false
product: 566978
modifier: 566990
reversible: true
type: Reaction

512334
stoichiometry: 1.0
species: 323949
type: SpeciesReference

528483
stoichiometry: 1.0
species: 325113
type: SpeciesReference

508746
stoichiometry: 1.0
species: 353865
type: SpeciesReference

R1446 p
reversible: true
type: Reaction
is part of: http://identifiers.org/ec-code/2.3.1.16
product: 472039
is: R03778
modifier: 472063
reactant: 472015
is: SBO:0000176
reactant: 472027
name: Octanoyl-CoA:acetyl-CoA C-acyltransferase [peroxisome]
fast: false
product: 472051

528795
stoichiometry: 1.0
species: 350709
type: SpeciesReference

568874
stoichiometry: 3.0
species: 323477
type: SpeciesReference

391238
stoichiometry: 1.0
species: 323766
type: SpeciesReference

507594
stoichiometry: 1.0
species: 334340
type: SpeciesReference

519743
stoichiometry: 1.0
species: 321625
type: SpeciesReference

471343
stoichiometry: 3.0
species: 321175
type: SpeciesReference

562194
stoichiometry: 1.0
species: 336583
type: SpeciesReference

R2012 r
reactant: 517528
modifier: 517552
name: bromobenzene-3,4-oxide hydrolase [endoplasmic reticulum membrane]
product: 517540
is part of: http://identifiers.org/ec-code/3.3.2.9
is: SBO:0000176
reversible: true
reactant: 517516
fast: false
type: Reaction
is: R07071

395393
stoichiometry: 1.0
species: 321274
type: SpeciesReference

362659
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

462333
stoichiometry: 1.0
species: 341057
type: SpeciesReference

R2576 cm
product: 561654
reactant: 561642
is: SBO:0000185
fast: false
reversible: true
name: Transport [mitochondrial membrane]
type: Reaction

R1934 m
name: (3S)-3-hydroxyacyl-CoA hydro-lyase [mitochondria]
modifier: 509358
reactant: 509310
reactant: 509298
is: SBO:0000176
is part of: http://identifiers.org/ec-code/4.2.1.17
reversible: false
modifier: 509346
type: Reaction
modifier: 509370
is: R06942
product: 509322
fast: false
modifier: 509334

498631
stoichiometry: 999.0
species: 326652
type: SpeciesReference

384206
stoichiometry: 1.0
species: 322340
type: SpeciesReference

553699
stoichiometry: 1.0
species: 325077
type: SpeciesReference

384818
stoichiometry: 1.0
species: 322403
type: SpeciesReference

423228
stoichiometry: 1.0
species: 321783
type: SpeciesReference

434530
stoichiometry: 1.0
species: 321187
type: SpeciesReference

398117
stoichiometry: 2.0
species: 321248
type: SpeciesReference

463869
stoichiometry: 1.0
species: 321783
type: SpeciesReference

487721
stoichiometry: 1.0
species: 322428
type: SpeciesReference

499879
stoichiometry: 1.0
species: 321783
type: SpeciesReference

470755
stoichiometry: 1.0
species: 337231
type: SpeciesReference

529167
stoichiometry: 1.0
species: 335348
type: SpeciesReference

441775
stoichiometry: 1.0
species: 321903
type: SpeciesReference

464685
stoichiometry: 1.0
species: 336151
type: SpeciesReference

460126
stoichiometry: 1.0
species: 321212
type: SpeciesReference

323962
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

358256
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

515211
stoichiometry: 1.0
species: 321698
type: SpeciesReference

558522
stoichiometry: 2.0
species: 336451
type: SpeciesReference

508638
stoichiometry: 1.0
species: 321150
type: SpeciesReference

460234
stoichiometry: 2.0
species: 321163
type: SpeciesReference

492844
stoichiometry: 1.0
species: 344372
type: SpeciesReference

373599
stoichiometry: 0.0
species: 327724
type: SpeciesReference

359624
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

371355
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

442243
stoichiometry: 1.0
species: 327640
type: SpeciesReference

400691
stoichiometry: 1.0
species: 328696
type: SpeciesReference

467793
stoichiometry: 1.0
species: 325101
type: SpeciesReference

352449
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

375170
stoichiometry: 1.0
species: 333764
type: SpeciesReference

491080
stoichiometry: 1.0
species: 321467
type: SpeciesReference

344060
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

372723
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

507354
stoichiometry: 1.0
species: 348081
type: SpeciesReference

384926
stoichiometry: 1.0
species: 321163
type: SpeciesReference

379767
stoichiometry: 1.0
species: 321187
type: SpeciesReference

389222
stoichiometry: 1.0
species: 325137
type: SpeciesReference

427799
stoichiometry: 1.0
species: 321540
type: SpeciesReference

R923 m
modifier: 431686
is: SBO:0000176
name: ATP:dGDP phosphotransferase [mitochondria]
reactant: 431650
fast: false
type: Reaction
product: 431674
reactant: 431638
product: 431662
reversible: true
is part of: http://identifiers.org/ec-code/2.7.4.6
is: R01857

473647
stoichiometry: 1.0
species: 325137
type: SpeciesReference

578976
stoichiometry: 1.0
species: 336439
type: SpeciesReference

423888
stoichiometry: 1.0
species: 323223
type: SpeciesReference

364951
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

416449
stoichiometry: 1.0
species: 331640
type: SpeciesReference

R934 c
type: Reaction
modifier: 432442
modifier: 432478
reactant: 432394
modifier: 432454
product: 432430
reactant: 432406
is: R01880
product: 432418
fast: false
is part of: http://identifiers.org/ec-code/2.7.1.48
modifier: 432466
reversible: false
name: dGTP:uridine 5'-phosphotransferase [cytosol]
is: SBO:0000176

442183
stoichiometry: 1.0
species: 327640
type: SpeciesReference

R1252 c
type: Reaction
reactant: 456754
modifier: 456826
reactant: 456778
product: 456790
fast: false
modifier: 456838
product: 456802
is: R02957
product: 456814
reactant: 456766
is: SBO:0000176
is part of: http://identifiers.org/ec-code/1.2.1.3
reversible: true
name: D-Glucuronolactone:NAD+ oxidoreductase [cytosol]

R1966 r
name: 1-nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming) [endoplasmic reticulum membrane]
reactant: 512634
reactant: 512646
reversible: false
is part of: http://identifiers.org/ec-code/2.5.1.18
type: Reaction
product: 512658
modifier: 512682
fast: false
is: SBO:0000176
modifier: 512694
modifier: 512670
is: R07025
modifier: 512706
modifier: 512718

554119
stoichiometry: 1.0
species: 322722
type: SpeciesReference

R1856 e
modifier: 504055
type: Reaction
product: 504043
is: SBO:0000176
is part of: http://identifiers.org/ec-code/2.4.1.149
reactant: 504019
is: R05975
fast: false
name: [plasma membrane]
reactant: 504007
reversible: true
product: 504031

471451
stoichiometry: 1.0
species: 337387
type: SpeciesReference

R2554 ec
product: 560370
modifier: 560418
name: Transport [plasma membrane]
product: 560382
type: Reaction
fast: false
reactant: 560346
reversible: false
is: SBO:0000185
product: 560394
modifier: 560406
reactant: 560334
reactant: 560358

421704
stoichiometry: 1.0
species: 336487
type: SpeciesReference

506334
stoichiometry: 1.0
species: 353289
type: SpeciesReference

482585
stoichiometry: 1.0
species: 345716
type: SpeciesReference

332444
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

568766
stoichiometry: 1.0
species: 326214
type: SpeciesReference

489256
stoichiometry: 1.0
species: 343502
type: SpeciesReference

346953
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

525454
stoichiometry: 1.0
species: 345704
type: SpeciesReference

545600
stoichiometry: 1.0
species: 321431
type: SpeciesReference

530499
stoichiometry: 1.0
species: 350817
type: SpeciesReference

513641
stoichiometry: 1.0
species: 321175
type: SpeciesReference

533679
stoichiometry: 1.0
species: 346651
type: SpeciesReference

426287
stoichiometry: 1.0
species: 325077
type: SpeciesReference

558630
stoichiometry: 1.0
species: 325101
type: SpeciesReference

566726
stoichiometry: 1.0
species: 321274
type: SpeciesReference

475014
stoichiometry: 1.0
species: 344492
type: SpeciesReference

R1522 p
is: R04204
type: Reaction
product: 478146
reactant: 478122
name: (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA hydro-liase [peroxisome]
fast: false
is part of: http://identifiers.org/ec-code/4.2.1.17
reversible: false
modifier: 478158
reactant: 478134
is: SBO:0000176

518794
stoichiometry: 1.0
species: 323998
type: SpeciesReference

332552
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

431027
stoichiometry: 1.0
species: 325077
type: SpeciesReference

362359
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

515367
stoichiometry: 1.0
species: 325077
type: SpeciesReference

419328
stoichiometry: 1.0
species: 327424
type: SpeciesReference

525393
stoichiometry: 1.0
species: 324143
type: SpeciesReference

475398
stoichiometry: 1.0
species: 336643
type: SpeciesReference

R2617 mc
reactant: 564082
modifier: 564121
fast: false
product: 564095
type: Reaction
is: SBO:0000185
reactant: 564069
name: Transport [mitochondrial membrane]
product: 564108
reversible: false

429803
stoichiometry: 1.0
species: 331411
type: SpeciesReference

345644
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

533739
stoichiometry: 1.0
species: 322183
type: SpeciesReference

370191
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

524882
stoichiometry: 1.0
species: 328168
type: SpeciesReference

462489
stoichiometry: 1.0
species: 335551
type: SpeciesReference

400871
stoichiometry: 1.0
species: 321431
type: SpeciesReference

367216
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

372615
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

412785
stoichiometry: 1.0
species: 329528
type: SpeciesReference

510978
stoichiometry: 1.0
species: 323949
type: SpeciesReference

524559
stoichiometry: 1.0
species: 330637
type: SpeciesReference

507030
stoichiometry: 1.0
species: 326033
type: SpeciesReference

391346
stoichiometry: 1.0
species: 321903
type: SpeciesReference

R2450 ce
reactant: 554167
modifier: 554251
type: Reaction
reactant: 554179
product: 554239
fast: false
product: 554227
is: SBO:0000185
name: Transport [plasma membrane]
reversible: false
product: 554203
product: 554215
reactant: 554191

460990
stoichiometry: 1.0
species: 339043
type: SpeciesReference

575005
stoichiometry: 1.0
species: 325125
type: SpeciesReference

543489
stoichiometry: 1.0
species: 340455
type: SpeciesReference

510822
stoichiometry: 1.0
species: 323937
type: SpeciesReference

506622
stoichiometry: 1.0
species: 353253
type: SpeciesReference

533463
stoichiometry: 1.0
species: 321163
type: SpeciesReference

561090
stoichiometry: 1.0
species: 332168
type: SpeciesReference

396077
stoichiometry: 1.0
species: 328708
type: SpeciesReference

R1748 m
modifier: 496213
modifier: 496226
modifier: 496239
modifier: 496200
is: SBO:0000176
product: 496174
reactant: 496135
product: 496161
reactant: 496122
is: R05050
fast: false
is part of: http://identifiers.org/ec-code/1.2.1.3
reactant: 496148
name: N4-Acetylaminobutanal:NAD+ oxidoreductase [mitochondria]
type: Reaction
product: 496187
reversible: false

351369
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

355280
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

429995
stoichiometry: 1.0
species: 329488
type: SpeciesReference

346531
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

R858 c
product: 426791
is: R01664
is: SBO:0000176
modifier: 426851
is part of: http://identifiers.org/ec-code/3.1.3.5
modifier: 426827
reactant: 426755
name: 2'-Deoxycytidine 5'-monophosphate phosphohydrolase [cytosol]
product: 426779
reversible: false
reactant: 426767
fast: false
modifier: 426803
modifier: 426815
type: Reaction
modifier: 426839

370539
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

326057
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

405082
stoichiometry: 1.0
species: 333188
type: SpeciesReference

529011
stoichiometry: 1.0
species: 353733
type: SpeciesReference

324776
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

357092
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

434422
stoichiometry: 1.0
species: 321163
type: SpeciesReference

354500
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

506082
stoichiometry: 1.0
species: 325582
type: SpeciesReference

562734
stoichiometry: 1.0
species: 333788
type: SpeciesReference

328827
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

542678
stoichiometry: 1.0
species: 347325
type: SpeciesReference

539102
stoichiometry: 1.0
species: 351357
type: SpeciesReference

458170
stoichiometry: 1.0
species: 321248
type: SpeciesReference

391573
stoichiometry: 1.0
species: 321515
type: SpeciesReference

346220
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

R2851 cp
product: 576169
reactant: 576157
is: SBO:0000185
fast: false
reversible: true
name: Transport [peroxisomal membrane]
type: Reaction

367000
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

336247
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

558007
stoichiometry: 1.0
species: 325658
type: SpeciesReference

459814
stoichiometry: 1.0
species: 334832
type: SpeciesReference

423456
stoichiometry: 1.0
species: 330077
type: SpeciesReference

484865
stoichiometry: 1.0
species: 325125
type: SpeciesReference

333500
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

406462
stoichiometry: 1.0
species: 325731
type: SpeciesReference

324204
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R2416 c
type: Reaction
modifier: 551995
modifier: 551983
is: SBO:0000176
product: 551947
reactant: 551899
modifier: 552007
fast: false
reactant: 551911
has part: http://identifiers.org/ec-code/1.3.1.20
is: R09420
reversible: true
name: carbonyl reductase [endoplasmic reticulum membrane]
has part: http://identifiers.org/ec-code/1.1.1.146
reactant: 551923
product: 551935
modifier: 551971
modifier: 551959

372867
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

446418
stoichiometry: 1.0
species: 340527
type: SpeciesReference

335192
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

R2518 cn
product: 558355
reactant: 558343
is: SBO:0000185
fast: false
reversible: true
name: Transport [nuclear membrane]
type: Reaction

321758
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

466089
stoichiometry: 1.0
species: 321964
type: SpeciesReference

513706
stoichiometry: 1.0
species: 345644
type: SpeciesReference

337051
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

563419
stoichiometry: 1.0
species: 330853
type: SpeciesReference

405286
stoichiometry: 1.0
species: 325607
type: SpeciesReference

468956
stoichiometry: 1.0
species: 322159
type: SpeciesReference

R75 lc
product: 375710
reactant: 375698
is: SBO:0000185
fast: false
reversible: false
name: Transport of beta-D-Fructose [lysosomal membrane]
type: Reaction

430943
stoichiometry: 1.0
species: 321515
type: SpeciesReference

508866
stoichiometry: 1.0
species: 321163
type: SpeciesReference

342607
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

359852
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

403559
stoichiometry: 1.0
species: 321467
type: SpeciesReference

470983
stoichiometry: 1.0
species: 321274
type: SpeciesReference

R94 cp
product: 376166
reactant: 376154
is: SBO:0000185
fast: false
reversible: false
name: Transport of (S)-3-Hydroxyisobutyryl-CoA [peroxisomal membrane]
type: Reaction

456466
stoichiometry: 1.0
species: 321175
type: SpeciesReference

367875
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

449430
stoichiometry: 1.0
species: 340515
type: SpeciesReference

335803
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

R1842 g
type: Reaction
modifier: 503131
name: [Golgi membrane]
is: SBO:0000176
fast: false
product: 503083
modifier: 503095
reversible: true
product: 503071
reactant: 503047
is: R05959
reactant: 503059
modifier: 503107
modifier: 503119

351069
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

442879
stoichiometry: 1.0
species: 345272
type: SpeciesReference

440635
stoichiometry: 1.0
species: 322612
type: SpeciesReference

R1709 c
modifier: 493180
reactant: 493132
reversible: false
reactant: 493144
name: Cyanoglycoside glucohydrolase [cytosol]
is: SBO:0000176
product: 493168
fast: false
type: Reaction
is: R04949
is part of: http://identifiers.org/ec-code/3.2.1.21
product: 493156

511602
stoichiometry: 1.0
species: 321686
type: SpeciesReference

390842
stoichiometry: 1.0
species: 323345
type: SpeciesReference

365563
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

322159
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

364471
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialmembrane
type: Species

322466
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

434974
stoichiometry: 1.0
species: 321613
type: SpeciesReference

R1901 r
reactant: 507066
is: R06264
name: expressed protein [endoplasmic reticulum membrane]
is: SBO:0000176
reactant: 507078
modifier: 507114
product: 507102
product: 507090
fast: false
reversible: false
type: Reaction

333068
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

523829
stoichiometry: 1.0
species: 321879
type: SpeciesReference

R1634 m
modifier: 486785
modifier: 486761
fast: false
reactant: 486713
modifier: 486773
product: 486725
is: SBO:0000176
is: R04746
is part of: http://identifiers.org/ec-code/4.2.1.17
name: (S)-Hydroxyoctanoyl-CoA hydro-lyase [mitochondria]
modifier: 486749
product: 486737
reversible: true
type: Reaction

324351
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

387638
stoichiometry: 1.0
species: 322856
type: SpeciesReference

446298
stoichiometry: 1.0
species: 336571
type: SpeciesReference

398728
stoichiometry: 1.0
species: 322097
type: SpeciesReference

387074
stoichiometry: 1.0
species: 322037
type: SpeciesReference

R1423 c
reactant: 470211
fast: false
product: 470273
modifier: 470285
reactant: 470224
product: 470261
type: Reaction
is: R03660
is: SBO:0000176
product: 470249
name: L-Phenylalanine:tRNA(Ala) ligase (AMP-forming) [cytosol]
is part of: http://identifiers.org/ec-code/6.1.1.20
reversible: false
reactant: 470237
modifier: 470297

361531
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosomalmembrane
type: Species

394765
stoichiometry: 1.0
species: 323962
type: SpeciesReference

332012
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

335731
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

362203
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

505842
stoichiometry: 1.0
species: 330137
type: SpeciesReference

375278
stoichiometry: 1.0
species: 334724
type: SpeciesReference

R2493 ec
modifier: 556675
type: Reaction
reversible: false
modifier: 556687
reactant: 556639
product: 556651
name: Transport [plasma membrane]
modifier: 556663
is: SBO:0000185
fast: false

523625
stoichiometry: 1.0
species: 322478
type: SpeciesReference

493804
stoichiometry: 1.0
species: 344816
type: SpeciesReference

R1583 n
name: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase [nucleus]
fast: false
reversible: false
type: Reaction
modifier: 482633
modifier: 482621
is: SBO:0000176
product: 482609
product: 482597
reactant: 482585
reactant: 482573
is: R04513
is part of: http://identifiers.org/ec-code/3.1.3.67

543038
stoichiometry: 1.0
species: 351693
type: SpeciesReference

568718
stoichiometry: 1.0
species: 325497
type: SpeciesReference

R2591 cm
name: Transport [mitochondrial membrane]
modifier: 562506
reactant: 562470
reactant: 562458
is: SBO:0000185
fast: false
reversible: false
product: 562494
type: Reaction
product: 562482

R2418 r
modifier: 552235
modifier: 552223
name: [endoplasmic reticulum membrane]
reactant: 552163
modifier: 552283
modifier: 552247
reactant: 552175
modifier: 552295
product: 552187
fast: false
is part of: http://identifiers.org/ec-code/2.4.1.17
is: R09427
product: 552199
reversible: true
modifier: 552259
modifier: 552211
modifier: 552271
is: SBO:0000176
type: Reaction

576097
stoichiometry: 1.0
species: 325077
type: SpeciesReference

R1086 c
modifier: 443443
reactant: 443395
reversible: false
is: SBO:0000176
type: Reaction
is: R02320
name: NTP:pyruvate O2-phosphotransferase [cytosol]
reactant: 443407
product: 443419
product: 443431
modifier: 443455
is part of: http://identifiers.org/ec-code/2.7.1.40
modifier: 443467
fast: false

532575
stoichiometry: 1.0
species: 337771
type: SpeciesReference

409186
stoichiometry: 1.0
species: 325972
type: SpeciesReference

353817
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

338995
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

481734
stoichiometry: 1.0
species: 341057
type: SpeciesReference

420336
stoichiometry: 1.0
species: 327496
type: SpeciesReference

497563
stoichiometry: 1.0
species: 346795
type: SpeciesReference

502831
stoichiometry: 1.0
species: 353409
type: SpeciesReference

376430
stoichiometry: 1.0
species: 351153
type: SpeciesReference

358076
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

467361
stoichiometry: 1.0
species: 336559
type: SpeciesReference

383438
stoichiometry: 2.0
species: 321843
type: SpeciesReference

329178
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

379311
stoichiometry: 2.0
species: 325197
type: SpeciesReference

R1387 m
reactant: 467337
name: ATP:dIDP phosphotransferase [mitochondrial inner membrane]
product: 467349
type: Reaction
product: 467361
is: R03530
fast: false
is part of: http://identifiers.org/ec-code/2.7.4.6
is: SBO:0000176
reactant: 467325
reversible: true
modifier: 467373

350265
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

398572
stoichiometry: 1.0
species: 324643
type: SpeciesReference

353973
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

455710
stoichiometry: 1.0
species: 322710
type: SpeciesReference

R2243 r
modifier: 535790
reversible: true
modifier: 535838
is part of: http://identifiers.org/ec-code/1.14.14.1
modifier: 535814
product: 535778
reactant: 535706
product: 535766
product: 535754
reactant: 535718
product: 535742
modifier: 535802
fast: false
modifier: 535826
name: [endoplasmic reticulum membrane]
type: Reaction
reactant: 535730
is: R08257
is: SBO:0000176

329794
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

413157
stoichiometry: 1.0
species: 329708
type: SpeciesReference

R1731 c
product: 494848
reactant: 494836
reactant: 494824
name: Tetradecanoyl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) [plasma membrane]
is: SBO:0000176
fast: false
reversible: true
product: 494872
modifier: 494896
is: R04967
modifier: 494884
type: Reaction
product: 494860
is part of: http://identifiers.org/ec-code/2.3.1.85

525235
stoichiometry: 1.0
species: 321187
type: SpeciesReference

438172
stoichiometry: 1.0
species: 330889
type: SpeciesReference

551383
stoichiometry: 1.0
species: 325077
type: SpeciesReference

346520
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

533307
stoichiometry: 1.0
species: 322025
type: SpeciesReference

467985
stoichiometry: 3.0
species: 321540
type: SpeciesReference

427247
stoichiometry: 1.0
species: 329056
type: SpeciesReference

567014
stoichiometry: 2.0
species: 336451
type: SpeciesReference

389006
stoichiometry: 1.0
species: 329955
type: SpeciesReference

R2344 m
product: 546212
modifier: 546248
product: 546200
reactant: 546176
is part of: http://identifiers.org/ec-code/1.14.13.15
reactant: 546188
is: R08725
is: SBO:0000176
reversible: true
modifier: 546236
type: Reaction
reactant: 546152
reactant: 546164
fast: false
product: 546224
name: 7alpha,26-dihydroxy-4-cholesten-3-one,NADPH:oxygen oxidoreductase (26-hydroxylating) [mitochondrial inner membrane]

501343
stoichiometry: 1.0
species: 327796
type: SpeciesReference

421008
stoichiometry: 1.0
species: 326214
type: SpeciesReference

522520
stoichiometry: 1.0
species: 349809
type: SpeciesReference

R1013 c
is part of: http://identifiers.org/ec-code/2.7.4.8
reversible: true
is: SBO:0000176
product: 438196
reactant: 438160
modifier: 438209
reactant: 438172
name: ATP:dGMP phosphotransferase [cytosol]
fast: false
type: Reaction
modifier: 438221
product: 438184
is: R02090

370755
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

408094
stoichiometry: 1.0
species: 325851
type: SpeciesReference

435370
stoichiometry: 1.0
species: 324956
type: SpeciesReference

533247
stoichiometry: 1.0
species: 321964
type: SpeciesReference

507138
stoichiometry: 1.0
species: 339612
type: SpeciesReference

556435
stoichiometry: 1.0
species: 321879
type: SpeciesReference

471919
stoichiometry: 1.0
species: 322013
type: SpeciesReference

340419
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

349353
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

414129
stoichiometry: 1.0
species: 322966
type: SpeciesReference

R787 m
product: 422004
is part of: http://identifiers.org/ec-code/2.1.3.3
reversible: true
reactant: 421992
modifier: 422028
reactant: 421980
type: Reaction
is: R01398
is: SBO:0000176
product: 422016
name: Carbamoyl-phosphate:L-ornithine carbamoyltransferase [mitochondria]
fast: false

478050
stoichiometry: 1.0
species: 339892
type: SpeciesReference

342752
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R1529 m
is: R04225
reversible: false
product: 478602
name: (S)-3-Methyl-2-oxopentanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating) [mitochondria]
modifier: 478638
type: Reaction
product: 478614
reactant: 478590
modifier: 478626
is: SBO:0000176
reactant: 478578
is part of: http://identifiers.org/ec-code/1.2.4.4
fast: false

339709
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R534 e
is: R00802
reversible: false
reactant: 404027
reactant: 404015
product: 404051
modifier: 404063
fast: false
is part of: http://identifiers.org/ec-code/3.2.1.20
product: 404039
is: SBO:0000176
type: Reaction
name: sucrose alpha-glucohydrolase [plasma membrane]

323100
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

415921
stoichiometry: 1.0
species: 322880
type: SpeciesReference

478686
stoichiometry: 1.0
species: 322159
type: SpeciesReference

412569
stoichiometry: 1.0
species: 332180
type: SpeciesReference

475170
stoichiometry: 1.0
species: 338713
type: SpeciesReference

423000
stoichiometry: 1.0
species: 327640
type: SpeciesReference

339600
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

R2281 r
modifier: 539942
is part of: http://identifiers.org/ec-code/1.14.14.1
reactant: 539894
is: SBO:0000176
modifier: 539978
fast: false
is: R08287
modifier: 539954
type: Reaction
reversible: true
modifier: 539930
modifier: 539966
name: [endoplasmic reticulum membrane]
product: 539906
product: 539918

347709
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

R2306 r
is: R08342
reversible: true
is: SBO:0000176
modifier: 542630
is part of: http://identifiers.org/ec-code/1.14.14.1
name: [endoplasmic reticulum membrane]
reactant: 542594
modifier: 542642
modifier: 542654
type: Reaction
fast: false
product: 542606
modifier: 542618
modifier: 542666

431698
stoichiometry: 1.0
species: 321323
type: SpeciesReference

462861
stoichiometry: 1.0
species: 335599
type: SpeciesReference

332840
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialintermembranespace
type: Species

R336 c
is part of: http://identifiers.org/ec-code/1.1.1.42
type: Reaction
product: 389258
name: oxalosuccinate carboxy-lyase (2-oxoglutarate-forming) [cytosol]
fast: false
reversible: true
reactant: 389246
is: SBO:0000176
modifier: 389282
product: 389270
is: R00268

R1699 p
name: 5-Hydroxyindoleacetaldehyde:NAD+ oxidoreductase [peroxisome]
type: Reaction
reversible: false
reactant: 492436
reactant: 492460
modifier: 492508
is: R04903
fast: false
reactant: 492448
is part of: http://identifiers.org/ec-code/1.2.1.3
is: SBO:0000176
product: 492496
product: 492472
product: 492484

397457
stoichiometry: 1.0
species: 322232
type: SpeciesReference

407722
stoichiometry: 1.0
species: 323465
type: SpeciesReference

R215 e
name: maltose glucohydrolase [plasma membrane]
type: Reaction
is: SBO:0000176
reversible: false
fast: false
is: R00028
product: 379227
reactant: 379215
is part of: http://identifiers.org/ec-code/3.2.1.20
reactant: 379203
modifier: 379239

493132
stoichiometry: 1.0
species: 321163
type: SpeciesReference

361579
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2191 r
modifier: 532215
is part of: http://identifiers.org/ec-code/1.11.1.7
is: R08107
name: [endoplasmic reticulum membrane]
fast: false
reactant: 532179
product: 532203
reversible: true
reactant: 532167
is: SBO:0000176
type: Reaction
product: 532191
modifier: 532227

575425
stoichiometry: 1.0
species: 327364
type: SpeciesReference

549896
stoichiometry: 1.0
species: 321163
type: SpeciesReference

428087
stoichiometry: 1.0
species: 329142
type: SpeciesReference

438715
stoichiometry: 1.0
species: 330963
type: SpeciesReference

376851
stoichiometry: 1.0
species: 324860
type: SpeciesReference

518368
stoichiometry: 1.0
species: 347313
type: SpeciesReference

365011
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

570614
stoichiometry: 1.0
species: 326968
type: SpeciesReference

R2744 ec
product: 570794
product: 570782
reactant: 570770
reactant: 570758
is: SBO:0000185
fast: false
reversible: false
name: Transport [plasma membrane]
type: Reaction

414971
stoichiometry: 1.0
species: 326919
type: SpeciesReference

369699
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

439819
stoichiometry: 1.0
species: 340925
type: SpeciesReference

336799
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

346328
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

533895
stoichiometry: 1.0
species: 351921
type: SpeciesReference

567230
stoichiometry: 1.0
species: 323211
type: SpeciesReference

400247
stoichiometry: 1.0
species: 323622
type: SpeciesReference

431182
stoichiometry: 1.0
species: 321163
type: SpeciesReference

521082
stoichiometry: 1.0
species: 349737
type: SpeciesReference

415465
stoichiometry: 1.0
species: 340270
type: SpeciesReference

419952
stoichiometry: 1.0
species: 321187
type: SpeciesReference

R350 c
modifier: 390134
is part of: http://identifiers.org/ec-code/2.4.1.11
reactant: 390098
reversible: true
is: SBO:0000176
is: R00292
type: Reaction
fast: false
modifier: 390122
name: UDP-glucose:glycogen 4-alpha-D-glucosyltransferase [cytosol]
product: 390110
reactant: 390086

384074
stoichiometry: 1.0
species: 321187
type: SpeciesReference

376707
stoichiometry: 1.0
species: 323345
type: SpeciesReference

329567
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

518212
stoichiometry: 1.0
species: 325077
type: SpeciesReference

562038
stoichiometry: 1.0
species: 330865
type: SpeciesReference

430727
stoichiometry: 1.0
species: 331688
type: SpeciesReference

376659
stoichiometry: 1.0
species: 322304
type: SpeciesReference

359780
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

343999
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2153 l
product: 529491
modifier: 529515
is part of: http://identifiers.org/ec-code/2.3.1.78
modifier: 529503
is: R07815
name: acetyl-CoA:heparan-alpha-D-glucosaminide N-acetyltransferase [lysosome]
reversible: true
reactant: 529455
is: SBO:0000176
product: 529479
fast: false
reactant: 529467
type: Reaction

502519
stoichiometry: 1.0
species: 346484
type: SpeciesReference

343307
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

410529
stoichiometry: 1.0
species: 321613
type: SpeciesReference

353661
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

563562
stoichiometry: 1.0
species: 336583
type: SpeciesReference

420456
stoichiometry: 1.0
species: 333332
type: SpeciesReference

483377
stoichiometry: 1.0
species: 341541
type: SpeciesReference

R2240 c
modifier: 535430
reversible: true
is part of: http://identifiers.org/ec-code/1.14.14.1
product: 535406
is: R08256
name: [endoplasmic reticulum membrane]
modifier: 535466
modifier: 535418
modifier: 535442
reactant: 535394
type: Reaction
modifier: 535454
is: SBO:0000176
fast: false

455938
stoichiometry: 1.0
species: 334088
type: SpeciesReference

411909
stoichiometry: 1.0
species: 326409
type: SpeciesReference

406246
stoichiometry: 1.0
species: 325695
type: SpeciesReference

437557
stoichiometry: 1.0
species: 326652
type: SpeciesReference

397853
stoichiometry: 1.0
species: 321163
type: SpeciesReference

474870
stoichiometry: 1.0
species: 338169
type: SpeciesReference

R1445 m
is part of: http://identifiers.org/ec-code/2.3.1.16
type: Reaction
name: Octanoyl-CoA:acetyl-CoA C-acyltransferase [mitochondrial inner membrane]
modifier: 472003
is: R03778
is: SBO:0000176
fast: false
product: 471991
product: 471979
reversible: true
reactant: 471955
reactant: 471967

391010
stoichiometry: 1.0
species: 321274
type: SpeciesReference

419844
stoichiometry: 1.0
species: 327640
type: SpeciesReference

392917
stoichiometry: 1.0
species: 322759
type: SpeciesReference

R1315 c
is: SBO:0000176
fast: false
modifier: 461697
product: 461661
reactant: 461649
type: Reaction
reactant: 461637
name: ITP:D-Tagatose 6-phosphate 1-phosphotransferase [plasma membrane]
product: 461673
reversible: true
modifier: 461685
is part of: http://identifiers.org/ec-code/2.7.1.11
is: R03239

R499 m
reactant: 401363
product: 401399
modifier: 401423
modifier: 401411
is part of: http://identifiers.org/ec-code/1.2.1.3
reactant: 401339
product: 401375
reversible: true
modifier: 401447
modifier: 401435
is: SBO:0000176
fast: false
type: Reaction
product: 401387
name: Acetaldehyde:NAD+ oxidoreductase [mitochondria]
reactant: 401351
is: R00710

R2578 ec
product: 561726
reactant: 561714
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

568022
stoichiometry: 1.0
species: 336451
type: SpeciesReference

555751
stoichiometry: 1.0
species: 336451
type: SpeciesReference

496447
stoichiometry: 1.0
species: 322880
type: SpeciesReference

551683
stoichiometry: 1.0
species: 322073
type: SpeciesReference

R1753 p
reactant: 496602
product: 496614
type: Reaction
is: R05053
reactant: 496590
product: 496626
is: SBO:0000176
reversible: true
name: D-Aspartate:2-oxoglutarate aminotransferase [peroxisome]
fast: false

459970
stoichiometry: 1.0
species: 322966
type: SpeciesReference

R2729 ec
product: 570170
reactant: 570158
is: SBO:0000185
fast: false
reversible: false
name: Transport [plasma membrane]
type: Reaction

350997
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

383774
stoichiometry: 1.0
species: 322146
type: SpeciesReference

510246
stoichiometry: 1.0
species: 348741
type: SpeciesReference

467577
stoichiometry: 1.0
species: 325077
type: SpeciesReference

565610
stoichiometry: 3.0
species: 340503
type: SpeciesReference

364327
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

463641
stoichiometry: 1.0
species: 340673
type: SpeciesReference

564338
stoichiometry: 1.0
species: 331832
type: SpeciesReference

R1906 g
reactant: 507342
modifier: 507402
product: 507378
fast: false
is: R06518
reversible: false
type: Reaction
reactant: 507354
is: SBO:0000176
modifier: 507390
name: N-acylsphingosine amidohydrolase [Golgi membrane]
is part of: http://identifiers.org/ec-code/3.5.1.23
product: 507366

432094
stoichiometry: 1.0
species: 350025
type: SpeciesReference

470839
stoichiometry: 1.0
species: 337243
type: SpeciesReference

447246
stoichiometry: 1.0
species: 321758
type: SpeciesReference

544112
stoichiometry: 1.0
species: 321479
type: SpeciesReference

386834
stoichiometry: 1.0
species: 322637
type: SpeciesReference

528675
stoichiometry: 2.0
species: 322478
type: SpeciesReference

R1750 m
type: Reaction
has part: http://identifiers.org/ec-code/1.5.1.12
product: 496408
reactant: 496369
reactant: 496356
is: SBO:0000176
product: 496395
reactant: 496343
has part: http://identifiers.org/ec-code/1.5.99.8
fast: false
modifier: 496434
product: 496382
modifier: 496421
is: R05051
reversible: true
name: L-erythro-4-Hydroxyglutamate:NAD+ oxidoreductase [mitochondria]

R2709 cm
product: 569282
reactant: 569270
is: SBO:0000185
fast: false
reversible: true
name: Transport [mitochondrial membrane]
type: Reaction

462261
stoichiometry: 1.0
species: 335803
type: SpeciesReference

467469
stoichiometry: 1.0
species: 322904
type: SpeciesReference

474763
stoichiometry: 1.0
species: 322478
type: SpeciesReference

R1507 m
modifier: 477030
type: Reaction
is: R04137
modifier: 477018
reactant: 476970
is part of: http://identifiers.org/ec-code/4.2.1.17
fast: false
reversible: true
modifier: 477006
product: 476994
modifier: 477042
name: 3-Hydroxyisopentyl-CoA hydro-lyase [mitochondria]
product: 476982
is: SBO:0000176

509802
stoichiometry: 1.0
species: 321698
type: SpeciesReference

400139
stoichiometry: 1.0
species: 321212
type: SpeciesReference

325461
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

563848
stoichiometry: 1.0
species: 333788
type: SpeciesReference

414835
stoichiometry: 1.0
species: 336643
type: SpeciesReference

R1110 r
fast: false
is: R02356
reversible: true
is part of: http://identifiers.org/ec-code/1.14.14.1
product: 445746
type: Reaction
modifier: 445794
reactant: 445710
is: SBO:0000176
reactant: 445734
modifier: 445818
modifier: 445782
name: [endoplasmic reticulum membrane]
modifier: 445806
reactant: 445722
product: 445770
product: 445758
reactant: 445698
modifier: 445830

358472
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

R2381 r
modifier: 548948
type: Reaction
reactant: 548912
is: R09290
is: SBO:0000176
product: 548924
reversible: true
modifier: 548960
fast: false
product: 548936
name: [endoplasmic reticulum membrane]
reactant: 548900

331484
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

361687
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

503083
stoichiometry: 1.0
species: 353481
type: SpeciesReference

452663
stoichiometry: 1.0
species: 333332
type: SpeciesReference

331339
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

462753
stoichiometry: 1.0
species: 322588
type: SpeciesReference

R2454 ec
product: 554431
product: 554419
reactant: 554407
reactant: 554395
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

572881
stoichiometry: 1.0
species: 327400
type: SpeciesReference

453335
stoichiometry: 1.0
species: 333752
type: SpeciesReference

R614 c
product: 409810
type: Reaction
modifier: 409822
is part of: http://identifiers.org/ec-code/2.4.1.83
reactant: 409786
is: R01009
reversible: false
fast: false
is: SBO:0000176
reactant: 409774
product: 409798
name: GDPmannose:dolichyl-phosphate O-beta-D-mannosyltransferase [endoplasmic reticulum membrane]

R2028 r
type: Reaction
modifier: 519496
product: 519444
reactant: 519366
modifier: 519509
reactant: 519405
modifier: 519483
modifier: 519470
modifier: 519457
is part of: http://identifiers.org/ec-code/1.14.14.1
reactant: 519392
is: SBO:0000176
fast: false
name: benzo[a]pyrene-7,8-diol, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing) [endoplasmic reticulum membrane]
reactant: 519379
is: R07085
product: 519431
product: 519418
reversible: true

353553
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

533007
stoichiometry: 1.0
species: 321964
type: SpeciesReference

339819
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

375614
stoichiometry: 1.0
species: 338023
type: SpeciesReference

543182
stoichiometry: 1.0
species: 337291
type: SpeciesReference

326166
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

423564
stoichiometry: 1.0
species: 327640
type: SpeciesReference

484301
stoichiometry: 1.0
species: 321467
type: SpeciesReference

510138
stoichiometry: 1.0
species: 321625
type: SpeciesReference

489448
stoichiometry: 1.0
species: 343515
type: SpeciesReference

430835
stoichiometry: 1.0
species: 323002
type: SpeciesReference

415357
stoichiometry: 1.0
species: 326956
type: SpeciesReference

326274
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

449586
stoichiometry: 1.0
species: 321163
type: SpeciesReference

417600
stoichiometry: 1.0
species: 340720
type: SpeciesReference

328935
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

399659
stoichiometry: 1.0
species: 322856
type: SpeciesReference

375758
stoichiometry: 1.0
species: 339491
type: SpeciesReference

550592
stoichiometry: 1.0
species: 352689
type: SpeciesReference

549788
stoichiometry: 2.0
species: 321163
type: SpeciesReference

325318
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

423672
stoichiometry: 1.0
species: 321274
type: SpeciesReference

534842
stoichiometry: 1.0
species: 325077
type: SpeciesReference

401351
stoichiometry: 1.0
species: 321431
type: SpeciesReference

555355
stoichiometry: 1.0
species: 324473
type: SpeciesReference

344288
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

340587
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

391681
stoichiometry: 1.0
species: 323429
type: SpeciesReference

523181
stoichiometry: 1.0
species: 328120
type: SpeciesReference

554239
stoichiometry: 3.0
species: 337723
type: SpeciesReference

515994
stoichiometry: 1.0
species: 349173
type: SpeciesReference

R2619 cm
fast: false
modifier: 564251
product: 564238
reversible: false
reactant: 564199
is: SBO:0000185
product: 564225
type: Reaction
reactant: 564212
name: Transport [mitochondrial membrane]

394441
stoichiometry: 1.0
species: 323887
type: SpeciesReference

350889
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

406354
stoichiometry: 1.0
species: 328696
type: SpeciesReference

483485
stoichiometry: 1.0
species: 321540
type: SpeciesReference

433930
stoichiometry: 1.0
species: 322159
type: SpeciesReference

502111
stoichiometry: 1.0
species: 326615
type: SpeciesReference

478794
stoichiometry: 1.0
species: 341105
type: SpeciesReference

367372
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

R1214 c
type: Reaction
name: (5-L-Glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing) [cytosol]
is part of: http://identifiers.org/ec-code/2.3.2.4
reversible: true
reactant: 453875
fast: false
modifier: 453911
product: 453887
product: 453899
is: R02743
is: SBO:0000176

470539
stoichiometry: 1.0
species: 338861
type: SpeciesReference

394657
stoichiometry: 1.0
species: 323887
type: SpeciesReference

398680
stoichiometry: 1.0
species: 324630
type: SpeciesReference

383894
stoichiometry: 1.0
species: 322195
type: SpeciesReference

340307
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

555055
stoichiometry: 1.0
species: 322880
type: SpeciesReference

453659
stoichiometry: 1.0
species: 321540
type: SpeciesReference

464469
stoichiometry: 1.0
species: 335959
type: SpeciesReference

345428
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

554947
stoichiometry: 1.0
species: 325077
type: SpeciesReference

507246
stoichiometry: 1.0
species: 334352
type: SpeciesReference

572125
stoichiometry: 1.0
species: 324812
type: SpeciesReference

501679
stoichiometry: 1.0
species: 322292
type: SpeciesReference

379203
stoichiometry: 1.0
species: 321187
type: SpeciesReference

R227 cl
modifier: 380223
modifier: 380211
modifier: 380379
modifier: 380151
product: 380127
reversible: false
product: 380115
modifier: 380427
modifier: 380403
type: Reaction
modifier: 380331
modifier: 380187
name: H+-transporting two-sector ATPase [lysosomal membrane]
is: R00086
modifier: 380235
reactant: 380091
modifier: 380199
modifier: 380175
modifier: 380439
modifier: 380295
modifier: 380415
is part of: http://identifiers.org/ec-code/3.6.3.14
modifier: 380391
modifier: 380355
modifier: 380343
modifier: 380283
reactant: 380103
modifier: 380247
modifier: 380319
modifier: 380307
is: SBO:0000185
modifier: 380367
product: 380139
modifier: 380271
reactant: 380079
modifier: 380259
fast: false
modifier: 380163

559038
stoichiometry: 1.0
species: 326166
type: SpeciesReference

522676
stoichiometry: 1.0
species: 323949
type: SpeciesReference

420228
stoichiometry: 1.0
species: 340925
type: SpeciesReference

354105
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

R1841 g
name: [Golgi membrane]
product: 503023
is part of: http://identifiers.org/ec-code/2.4.99.8
type: Reaction
reversible: true
fast: false
modifier: 503035
is: SBO:0000176
is: R05958
reactant: 502987
reactant: 502999
product: 503011

374379
stoichiometry: 1.0
species: 326274
type: SpeciesReference

502723
stoichiometry: 1.0
species: 324131
type: SpeciesReference

376322
stoichiometry: 1.0
species: 347733
type: SpeciesReference

444918
stoichiometry: 1.0
species: 334760
type: SpeciesReference

558858
stoichiometry: 1.0
species: 336763
type: SpeciesReference

534614
stoichiometry: 1.0
species: 326310
type: SpeciesReference

454103
stoichiometry: 1.0
species: 333584
type: SpeciesReference

463413
stoichiometry: 1.0
species: 345272
type: SpeciesReference

383546
stoichiometry: 1.0
species: 321163
type: SpeciesReference

477834
stoichiometry: 1.0
species: 322856
type: SpeciesReference

529851
stoichiometry: 1.0
species: 354129
type: SpeciesReference

346807
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

329069
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

460690
stoichiometry: 1.0
species: 322966
type: SpeciesReference

363883
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialinnermembrane
type: Species

432406
stoichiometry: 1.0
species: 329781
type: SpeciesReference

333692
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

503683
stoichiometry: 1.0
species: 323345
type: SpeciesReference

424092
stoichiometry: 1.0
species: 339709
type: SpeciesReference

359024
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

454715
stoichiometry: 1.0
species: 325077
type: SpeciesReference

R761 r
fast: false
product: 420420
reactant: 420396
product: 420408
modifier: 420432
type: Reaction
is: SBO:0000176
is: R01318
name: Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase [endoplasmic reticulum membrane]
reactant: 420384
is part of: http://identifiers.org/ec-code/2.3.1.23
reversible: true

357500
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

544976
stoichiometry: 1.0
species: 321552
type: SpeciesReference

489149
stoichiometry: 1.0
species: 321515
type: SpeciesReference

389114
stoichiometry: 1.0
species: 322097
type: SpeciesReference

368871
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

502939
stoichiometry: 1.0
species: 324131
type: SpeciesReference

324630
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

460546
stoichiometry: 1.0
species: 322820
type: SpeciesReference

497671
stoichiometry: 2.0
species: 325137
type: SpeciesReference

337327
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

501451
stoichiometry: 1.0
species: 322292
type: SpeciesReference

375062
stoichiometry: 1.0
species: 332912
type: SpeciesReference

332996
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

397349
stoichiometry: 1.0
species: 321819
type: SpeciesReference

531195
stoichiometry: 1.0
species: 351057
type: SpeciesReference

532683
stoichiometry: 1.0
species: 321236
type: SpeciesReference

383330
stoichiometry: 1.0
species: 322539
type: SpeciesReference

R676 m
reactant: 413889
modifier: 413925
is part of: http://identifiers.org/ec-code/2.7.4.6
is: R01137
name: ATP:dADP phosphotransferase [mitochondrial inner membrane]
fast: false
product: 413913
reactant: 413877
product: 413901
type: Reaction
is: SBO:0000176
reversible: true

564225
stoichiometry: 1.0
species: 330925
type: SpeciesReference

385598
stoichiometry: 1.0
species: 328468
type: SpeciesReference

plasmamembrane
is: GO:0005886
is: SBO:0000290
constant: true
size: NaN
spatial dimensions: 3.0
name: plasma membrane
type: Compartment

482154
stoichiometry: 1.0
species: 321879
type: SpeciesReference

328708
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

412677
stoichiometry: 1.0
species: 321686
type: SpeciesReference

376202
stoichiometry: 1.0
species: 346531
type: SpeciesReference

416341
stoichiometry: 1.0
species: 331616
type: SpeciesReference

423336
stoichiometry: 1.0
species: 328252
type: SpeciesReference

477918
stoichiometry: 1.0
species: 339868
type: SpeciesReference

485657
stoichiometry: 1.0
species: 342427
type: SpeciesReference

332120
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

482094
stoichiometry: 1.0
species: 321163
type: SpeciesReference

555739
stoichiometry: 1.0
species: 324510
type: SpeciesReference

462849
stoichiometry: 1.0
species: 321383
type: SpeciesReference

347193
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

362011
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialoutermembrane
type: Species

346735
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

528195
stoichiometry: 1.0
species: 321662
type: SpeciesReference

R1245 p
type: Reaction
modifier: 456214
modifier: 456250
product: 456178
reactant: 456142
product: 456202
reversible: true
reactant: 456154
fast: false
modifier: 456238
reactant: 456166
is: SBO:0000176
is part of: http://identifiers.org/ec-code/1.4.3.3
modifier: 456226
name: D-Arginine:oxygen oxidoreductase (deaminating) [peroxisome]
product: 456190
is: R02923

R191 ec
product: 378495
reactant: 378483
is: SBO:0000185
fast: false
reversible: false
name: Transport of R-S-Cysteinylglycine [plasma membrane]
type: Reaction

322037
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

398825
stoichiometry: 1.0
species: 324715
type: SpeciesReference

369483
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

474439
stoichiometry: 2.0
species: 325125
type: SpeciesReference

557947
stoichiometry: 1.0
species: 321783
type: SpeciesReference

321613
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

377919
stoichiometry: 1.0
species: 338337
type: SpeciesReference

R2805 ec
modifier: 573673
product: 573661
reactant: 573649
is: SBO:0000185
fast: false
reversible: false
name: Transport [plasma membrane]
type: Reaction

511506
stoichiometry: 1.0
species: 321625
type: SpeciesReference

321540
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

330247
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2469 ec
modifier: 555139
product: 555127
fast: false
type: Reaction
reactant: 555103
is: SBO:0000185
name: Transport [plasma membrane]
reactant: 555091
reversible: true
product: 555115

435802
stoichiometry: 1.0
species: 330552
type: SpeciesReference

377703
stoichiometry: 1.0
species: 333248
type: SpeciesReference

440539
stoichiometry: 1.0
species: 321710
type: SpeciesReference

329580
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

523277
stoichiometry: 1.0
species: 348297
type: SpeciesReference

470224
stoichiometry: 1.0
species: 325017
type: SpeciesReference

371907
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

426143
stoichiometry: 1.0
species: 343187
type: SpeciesReference

367755
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1656 m
reversible: false
fast: false
name: Selenomethionine:tRNAMet ligase (AMP-forming) [mitochondria]
reactant: 488237
is: SBO:0000176
modifier: 488309
is part of: http://identifiers.org/ec-code/6.1.1.10
reactant: 488261
product: 488273
product: 488285
reactant: 488249
product: 488297
is: R04773
type: Reaction

R778 c
product: 421404
fast: false
reactant: 421380
modifier: 421440
is part of: http://identifiers.org/ec-code/1.1.1.30
is: SBO:0000176
is: R01361
product: 421428
reactant: 421392
product: 421416
name: (R)-3-Hydroxybutanoate:NAD+ oxidoreductase [cytosol]
reversible: true
type: Reaction

R2185 m
name: [mitochondrial inner membrane]
reactant: 531759
is: SBO:0000176
reversible: true
is: R07953
product: 531783
product: 531771
reactant: 531747
is part of: http://identifiers.org/ec-code/2.3.1.16
modifier: 531795
fast: false
type: Reaction

568166
stoichiometry: 1.0
species: 324498
type: SpeciesReference

R176 cm
product: 378135
reactant: 378123
is: SBO:0000185
fast: false
reversible: false
name: Transport of Folinic acid [mitochondrial membrane]
type: Reaction

R1162 m
modifier: 450017
type: Reaction
is part of: http://identifiers.org/ec-code/3.1.4.12
product: 450005
name: Sphingomyelin cholinephosphohydrolase [mitochondrial inner membrane]
is: R02541
reactant: 449969
is: SBO:0000176
product: 449993
reversible: false
fast: false
reactant: 449981

508986
stoichiometry: 1.0
species: 321187
type: SpeciesReference

R1378 c
is: SBO:0000176
modifier: 466629
is: R03479
is part of: http://identifiers.org/ec-code/2.7.1.134
product: 466605
reactant: 466569
type: Reaction
modifier: 466617
product: 466593
reversible: true
fast: false
name: ATP:1D-myo-inositol-3,4,5,6-tetrakisphosphate 1-phosphotransferase [cytosol]
reactant: 466581

468836
stoichiometry: 1.0
species: 321323
type: SpeciesReference

367144
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

377811
stoichiometry: 1.0
species: 335396
type: SpeciesReference

445458
stoichiometry: 1.0
species: 321175
type: SpeciesReference

R2670 ec
fast: false
is: SBO:0000185
product: 567026
product: 567038
name: Transport [plasma membrane]
reversible: true
reactant: 567002
reactant: 567014
type: Reaction
modifier: 567050

R921 c
is: SBO:0000176
reactant: 431482
modifier: 431518
is: R01857
product: 431506
fast: false
name: ATP:dGDP phosphotransferase [cytosol]
type: Reaction
modifier: 431542
product: 431494
is part of: http://identifiers.org/ec-code/2.7.4.6
reversible: true
modifier: 431566
modifier: 431530
reactant: 431470
modifier: 431554

462105
stoichiometry: 1.0
species: 335491
type: SpeciesReference

337483
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

390086
stoichiometry: 999.0
species: 323076
type: SpeciesReference

330394
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialintermembranespace
type: Species

391453
stoichiometry: 1.0
species: 324824
type: SpeciesReference

322588
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

329357
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

542774
stoichiometry: 1.0
species: 351681
type: SpeciesReference

456586
stoichiometry: 1.0
species: 321515
type: SpeciesReference

376995
stoichiometry: 1.0
species: 325607
type: SpeciesReference

524117
stoichiometry: 1.0
species: 321613
type: SpeciesReference

490096
stoichiometry: 1.0
species: 322625
type: SpeciesReference

498955
stoichiometry: 1.0
species: 322183
type: SpeciesReference

R853 m
reactant: 426443
product: 426479
product: 426467
is: SBO:0000176
name: Dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase [mitochondria]
fast: false
reversible: false
is: R01658
type: Reaction
reactant: 426455
is part of: http://identifiers.org/ec-code/2.5.1.1
modifier: 426491

388574
stoichiometry: 1.0
species: 330358
type: SpeciesReference

411801
stoichiometry: 1.0
species: 326360
type: SpeciesReference

R2345 m
reversible: true
product: 546320
modifier: 546356
reactant: 546284
is part of: http://identifiers.org/ec-code/1.14.13.15
reactant: 546296
product: 546308
fast: false
modifier: 546344
reactant: 546260
reactant: 546272
is: SBO:0000176
name: cholest-5-ene-3beta,26-diol,NADPH:oxygen oxidoreductase (26-hydroxylating) [mitochondrial inner membrane]
is: R08726
product: 546332
type: Reaction

489652
stoichiometry: 1.0
species: 321686
type: SpeciesReference

553291
stoichiometry: 3.0
species: 329659
type: SpeciesReference

506766
stoichiometry: 1.0
species: 340685
type: SpeciesReference

R1049 m
reactant: 440803
is: SBO:0000176
name: L-Isoleucine:oxygen oxidoreductase (deaminating) [mitochondria]
type: Reaction
reactant: 440791
product: 440839
product: 440827
is: R02197
modifier: 440863
is part of: http://identifiers.org/ec-code/1.4.3.2
reactant: 440815
reversible: true
product: 440851
fast: false

347001
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

433030
stoichiometry: 1.0
species: 343163
type: SpeciesReference

559050
stoichiometry: 1.0
species: 336439
type: SpeciesReference

R2476 ec
product: 555619
modifier: 555643
product: 555607
is: SBO:0000185
reactant: 555595
reversible: true
fast: false
type: Reaction
modifier: 555631
reactant: 555583
name: Transport [plasma membrane]

575125
stoichiometry: 1.0
species: 332000
type: SpeciesReference

500059
stoichiometry: 1.0
species: 323333
type: SpeciesReference

471355
stoichiometry: 1.0
species: 322390
type: SpeciesReference

518807
stoichiometry: 1.0
species: 349389
type: SpeciesReference

562182
stoichiometry: 1.0
species: 333788
type: SpeciesReference

568886
stoichiometry: 1.0
species: 325077
type: SpeciesReference

539390
stoichiometry: 1.0
species: 351369
type: SpeciesReference

453023
stoichiometry: 1.0
species: 334040
type: SpeciesReference

R33 cm
product: 374702
reactant: 374690
is: SBO:0000185
fast: false
reversible: false
name: Transport of (R)-Lactate [mitochondrial membrane]
type: Reaction

492436
stoichiometry: 1.0
species: 321248
type: SpeciesReference

498643
stoichiometry: 1.0
species: 331700
type: SpeciesReference

462321
stoichiometry: 1.0
species: 325125
type: SpeciesReference

429707
stoichiometry: 1.0
species: 329462
type: SpeciesReference

362647
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

567134
stoichiometry: 1.0
species: 327208
type: SpeciesReference

431470
stoichiometry: 1.0
species: 321274
type: SpeciesReference

398129
stoichiometry: 1.0
species: 324606
type: SpeciesReference

R196 cp
product: 378615
reactant: 378603
is: SBO:0000185
fast: false
reversible: false
name: Transport of N4-Acetylaminobutanal [peroxisomal membrane]
type: Reaction

434542
stoichiometry: 1.0
species: 330901
type: SpeciesReference

384218
stoichiometry: 1.0
species: 321915
type: SpeciesReference

515223
stoichiometry: 1.0
species: 325089
type: SpeciesReference

553687
stoichiometry: 1.0
species: 330430
type: SpeciesReference

358268
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

558534
stoichiometry: 1.0
species: 321783
type: SpeciesReference

460138
stoichiometry: 1.0
species: 344468
type: SpeciesReference

R1645 m
fast: false
name: trans-Dec-2-enoyl-CoA reductase [mitochondrial inner membrane]
product: 487541
reactant: 487517
is: R04753
is: SBO:0000176
product: 487553
type: Reaction
modifier: 487565
reversible: true
is part of: http://identifiers.org/ec-code/1.3.1.38
reactant: 487505
product: 487529

330793
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

487733
stoichiometry: 1.0
species: 342740
type: SpeciesReference

529155
stoichiometry: 1.0
species: 353733
type: SpeciesReference

470767
stoichiometry: 1.0
species: 322159
type: SpeciesReference

464673
stoichiometry: 1.0
species: 321163
type: SpeciesReference

441763
stoichiometry: 1.0
species: 331411
type: SpeciesReference

538466
stoichiometry: 1.0
species: 346953
type: SpeciesReference

434854
stoichiometry: 1.0
species: 321576
type: SpeciesReference

479166
stoichiometry: 1.0
species: 343477
type: SpeciesReference

R1967 p
modifier: 512766
is part of: http://identifiers.org/ec-code/2.5.1.18
name: 1-nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming) [peroxisome]
type: Reaction
reactant: 512730
product: 512754
is: R07025
reversible: false
fast: false
is: SBO:0000176
reactant: 512742

412881
stoichiometry: 1.0
species: 322121
type: SpeciesReference

446178
stoichiometry: 1.0
species: 332024
type: SpeciesReference

489352
stoichiometry: 1.0
species: 321686
type: SpeciesReference

574333
stoichiometry: 1.0
species: 334004
type: SpeciesReference

528339
stoichiometry: 1.0
species: 328756
type: SpeciesReference

398273
stoichiometry: 1.0
species: 321686
type: SpeciesReference

368511
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

363739
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

R1935 p
is part of: http://identifiers.org/ec-code/4.2.1.17
is: R06942
fast: false
name: (3S)-3-hydroxyacyl-CoA hydro-lyase [peroxisome]
reactant: 509394
is: SBO:0000176
reversible: false
modifier: 509418
reactant: 509382
type: Reaction
product: 509406

475230
stoichiometry: 1.0
species: 321674
type: SpeciesReference

391142
stoichiometry: 1.0
species: 321163
type: SpeciesReference

419100
stoichiometry: 1.0
species: 327424
type: SpeciesReference

R636 c
type: Reaction
is part of: http://identifiers.org/ec-code/2.2.1.1
reversible: true
reactant: 411165
name: D-Fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase [cytosol]
modifier: 411225
reactant: 411177
fast: false
modifier: 411213
product: 411201
is: SBO:0000176
is: R01067
product: 411189

537794
stoichiometry: 1.0
species: 321686
type: SpeciesReference

345596
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

476334
stoichiometry: 1.0
species: 321467
type: SpeciesReference

R898 m
is: SBO:0000176
reactant: 429791
is part of: http://identifiers.org/ec-code/2.7.7.41
name: CTP:phosphatidate cytidyltransferase [mitochondrial inner membrane]
is: R01799
type: Reaction
reversible: false
fast: false
modifier: 429839
reactant: 429803
product: 429815
product: 429827

463857
stoichiometry: 1.0
species: 335899
type: SpeciesReference

493516
stoichiometry: 1.0
species: 325077
type: SpeciesReference

529719
stoichiometry: 1.0
species: 353769
type: SpeciesReference

481854
stoichiometry: 1.0
species: 345596
type: SpeciesReference

463209
stoichiometry: 1.0
species: 342220
type: SpeciesReference

349209
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

432322
stoichiometry: 1.0
species: 332024
type: SpeciesReference

389342
stoichiometry: 1.0
species: 343163
type: SpeciesReference

495953
stoichiometry: 1.0
species: 345488
type: SpeciesReference

519730
stoichiometry: 1.0
species: 321175
type: SpeciesReference

379647
stoichiometry: 4.0
species: 349113
type: SpeciesReference

473527
stoichiometry: 1.0
species: 325125
type: SpeciesReference

528495
stoichiometry: 1.0
species: 350685
type: SpeciesReference

R645 m
product: 411801
is: SBO:0000176
is part of: http://identifiers.org/ec-code/3.5.1.12
name: N6-D-Biotinyl-L-lysine amidohydrolase [mitochondria]
modifier: 411813
reactant: 411765
fast: false
reversible: true
product: 411789
type: Reaction
is: R01077
reactant: 411777

533535
stoichiometry: 1.0
species: 338229
type: SpeciesReference

447102
stoichiometry: 1.0
species: 322880
type: SpeciesReference

476406
stoichiometry: 1.0
species: 321395
type: SpeciesReference

492964
stoichiometry: 1.0
species: 344516
type: SpeciesReference

421608
stoichiometry: 1.0
species: 322061
type: SpeciesReference

371259
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialmembrane
type: Species

400571
stoichiometry: 1.0
species: 321383
type: SpeciesReference

487841
stoichiometry: 1.0
species: 342812
type: SpeciesReference

564350
stoichiometry: 1.0
species: 328384
type: SpeciesReference

374091
stoichiometry: 1.0
species: 324739
type: SpeciesReference

354608
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R995 c
is: R02053
name: Phosphatidylethanolamine 2-acylhydrolase [cytosol]
product: 436918
modifier: 436942
is part of: http://identifiers.org/ec-code/3.1.1.4
reactant: 436882
product: 436906
reactant: 436894
fast: false
is: SBO:0000176
reversible: true
type: Reaction
modifier: 436930

566714
stoichiometry: 1.0
species: 321163
type: SpeciesReference

323260
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

346965
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

415609
stoichiometry: 1.0
species: 321867
type: SpeciesReference

558642
stoichiometry: 1.0
species: 326335
type: SpeciesReference

475026
stoichiometry: 1.0
species: 321187
type: SpeciesReference

516461
stoichiometry: 1.0
species: 349185
type: SpeciesReference

426299
stoichiometry: 1.0
species: 328839
type: SpeciesReference

515379
stoichiometry: 1.0
species: 328660
type: SpeciesReference

419316
stoichiometry: 1.0
species: 322576
type: SpeciesReference

542090
stoichiometry: 1.0
species: 347217
type: SpeciesReference

524546
stoichiometry: 1.0
species: 341491
type: SpeciesReference

332564
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

431015
stoichiometry: 1.0
species: 321467
type: SpeciesReference

352305
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

R426 c
type: Reaction
reversible: false
reactant: 395789
modifier: 395873
name: GTP:cytidine 5'-phosphotransferase [cytosol]
product: 395825
is: SBO:0000176
is: R00517
modifier: 395849
product: 395813
modifier: 395861
fast: false
is part of: http://identifiers.org/ec-code/2.7.1.48
modifier: 395837
reactant: 395801

R2038 r
reversible: false
modifier: 520796
reactant: 520718
fast: false
name: chloroacetyl-chloride:glutathione S-chloroacetyltransferase [endoplasmic reticulum membrane]
modifier: 520757
type: Reaction
is: R07093
product: 520731
modifier: 520783
modifier: 520809
reactant: 520705
modifier: 520770
product: 520744
is part of: http://identifiers.org/ec-code/2.5.1.18
is: SBO:0000176

462477
stoichiometry: 1.0
species: 322415
type: SpeciesReference

517564
stoichiometry: 1.0
species: 321175
type: SpeciesReference

453179
stoichiometry: 1.0
species: 321879
type: SpeciesReference

429815
stoichiometry: 1.0
species: 322183
type: SpeciesReference

475386
stoichiometry: 1.0
species: 338713
type: SpeciesReference

345656
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

382047
stoichiometry: 2.0
species: 334904
type: SpeciesReference

457090
stoichiometry: 1.0
species: 321528
type: SpeciesReference

391358
stoichiometry: 1.0
species: 323369
type: SpeciesReference

372627
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

367204
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

502951
stoichiometry: 1.0
species: 353457
type: SpeciesReference

412773
stoichiometry: 1.0
species: 324449
type: SpeciesReference

575713
stoichiometry: 1.0
species: 324510
type: SpeciesReference

410206
stoichiometry: 1.0
species: 322772
type: SpeciesReference

359636
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

R2106 c
reversible: false
type: Reaction
is part of: http://identifiers.org/ec-code/5.3.3.5
reactant: 526156
is: R07484
modifier: 526180
name: HYD1 (Hydra 1) [endoplasmic reticulum membrane]
product: 526168
is: SBO:0000176
fast: false

371367
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

442231
stoichiometry: 1.0
species: 331460
type: SpeciesReference

512478
stoichiometry: 1.0
species: 323937
type: SpeciesReference

460246
stoichiometry: 1.0
species: 326555
type: SpeciesReference

507366
stoichiometry: 1.0
species: 327640
type: SpeciesReference

R1259 e
fast: false
name: Deamino-NAD+ nucleotidohydrolase [plasma membrane]
is: R03004
reactant: 457342
product: 457378
product: 457366
modifier: 457390
is part of: http://identifiers.org/ec-code/3.6.1.9
reactant: 457354
type: Reaction
is: SBO:0000176
reversible: true

384938
stoichiometry: 1.0
species: 322440
type: SpeciesReference

373407
stoichiometry: 1.0
species: 328132
type: SpeciesReference

546572
stoichiometry: 1.0
species: 352317
type: SpeciesReference

R772 c
name: 1-acylglycerol acylhydrolase [plasma membrane]
is: R01351
modifier: 421056
reactant: 420996
type: Reaction
is part of: http://identifiers.org/ec-code/3.1.1.23
product: 421008
is: SBO:0000176
modifier: 421032
reversible: true
reactant: 420984
modifier: 421044
fast: false
product: 421020

445878
stoichiometry: 1.0
species: 347637
type: SpeciesReference

R1236 r
reactant: 455446
modifier: 455530
type: Reaction
modifier: 455542
reactant: 455434
modifier: 455566
modifier: 455494
modifier: 455506
name: [endoplasmic reticulum membrane]
product: 455470
reversible: true
is part of: http://identifiers.org/ec-code/2.4.1.17
product: 455458
modifier: 455554
modifier: 455482
fast: false
is: R02902
is: SBO:0000176
modifier: 455518

505243
stoichiometry: 1.0
species: 341616
type: SpeciesReference

372735
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

345440
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

463701
stoichiometry: 1.0
species: 336307
type: SpeciesReference

473635
stoichiometry: 1.0
species: 321528
type: SpeciesReference

423876
stoichiometry: 1.0
species: 335887
type: SpeciesReference

506346
stoichiometry: 1.0
species: 323333
type: SpeciesReference

364963
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

466605
stoichiometry: 1.0
species: 336283
type: SpeciesReference

489244
stoichiometry: 1.0
species: 325137
type: SpeciesReference

420684
stoichiometry: 1.0
species: 327520
type: SpeciesReference

R1103 c
product: 444822
reactant: 444786
modifier: 444882
is: R02353
reversible: true
product: 444798
modifier: 444894
product: 444810
modifier: 444834
is: SBO:0000176
type: Reaction
modifier: 444870
is part of: http://identifiers.org/ec-code/1.1.1.62
modifier: 444858
fast: false
name: Estradiol-17beta:NADP+ 17-oxidoreductase [endoplasmic reticulum membrane]
modifier: 444846
reactant: 444774

332456
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

482597
stoichiometry: 1.0
species: 321939
type: SpeciesReference

568778
stoichiometry: 1.0
species: 326226
type: SpeciesReference

425603
stoichiometry: 1.0
species: 345644
type: SpeciesReference

442171
stoichiometry: 1.0
species: 331460
type: SpeciesReference

470611
stoichiometry: 1.0
species: 322503
type: SpeciesReference

R1768 m
reactant: 497563
name: [mitochondria]
modifier: 497623
fast: false
reactant: 497551
type: Reaction
is: R05237
reversible: true
product: 497587
modifier: 497635
is: SBO:0000176
modifier: 497611
is part of: http://identifiers.org/ec-code/1.2.1.3
product: 497575
modifier: 497599

442807
stoichiometry: 1.0
species: 339491
type: SpeciesReference

421716
stoichiometry: 1.0
species: 322316
type: SpeciesReference

471463
stoichiometry: 1.0
species: 321613
type: SpeciesReference

R2843 ce
product: 575545
reactant: 575497
product: 575533
product: 575557
fast: false
modifier: 575569
reversible: false
type: Reaction
is: SBO:0000185
reactant: 575509
name: Transport [plasma membrane]
reactant: 575521
modifier: 575581

405274
stoichiometry: 1.0
species: 321163
type: SpeciesReference

521290
stoichiometry: 1.0
species: 349761
type: SpeciesReference

467133
stoichiometry: 1.0
species: 336547
type: SpeciesReference

461097
stoichiometry: 1.0
species: 335288
type: SpeciesReference

508878
stoichiometry: 1.0
species: 330624
type: SpeciesReference

359864
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

430955
stoichiometry: 1.0
species: 325125
type: SpeciesReference

342619
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

468944
stoichiometry: 1.0
species: 336931
type: SpeciesReference

337063
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

335180
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2609 mc
type: Reaction
fast: false
reactant: 563562
reversible: false
product: 563588
modifier: 563601
name: Transport [mitochondrial membrane]
is: SBO:0000185
product: 563575
reactant: 563549

322146
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

R2649 cr
product: 566042
reactant: 566030
is: SBO:0000185
fast: false
reversible: false
name: Transport [endoplasmic reticulum membrane]
type: Reaction

415909
stoichiometry: 1.0
species: 321964
type: SpeciesReference

506490
stoichiometry: 1.0
species: 323333
type: SpeciesReference

523169
stoichiometry: 1.0
species: 325077
type: SpeciesReference

335815
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

389954
stoichiometry: 1.0
species: 325912
type: SpeciesReference

R967 l
reactant: 434830
reactant: 434842
product: 434866
is: SBO:0000176
is: R01976
product: 434878
type: Reaction
name: (S)-3-Hydroxybutanoyl-CoA:NADP+ oxidoreductase [lysosome]
fast: false
reversible: true
product: 434854

367863
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

456478
stoichiometry: 1.0
species: 321395
type: SpeciesReference

368307
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

R1361 c
product: 465309
is: R03417
reactant: 465273
reversible: true
is: SBO:0000176
type: Reaction
fast: false
modifier: 465333
is part of: http://identifiers.org/ec-code/3.1.1.5
modifier: 465321
reactant: 465285
product: 465297
name: L-2-Lysophosphatidylethanolamine aldehydohydrolase [endoplasmic reticulum membrane]

387770
stoichiometry: 1.0
species: 325125
type: SpeciesReference

R2789 ce
fast: false
product: 572749
reversible: true
name: Transport [plasma membrane]
is: SBO:0000185
modifier: 572761
type: Reaction
product: 572737
modifier: 572785
reactant: 572713
modifier: 572773
reactant: 572725

440647
stoichiometry: 1.0
species: 352425
type: SpeciesReference

459262
stoichiometry: 1.0
species: 342945
type: SpeciesReference

365551
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

390830
stoichiometry: 1.0
species: 321274
type: SpeciesReference

511614
stoichiometry: 1.0
species: 325077
type: SpeciesReference

322478
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

438871
stoichiometry: 1.0
species: 324143
type: SpeciesReference

R2892 gc
product: 578496
product: 578484
fast: false
is: SBO:0000185
reactant: 578472
reactant: 578460
reversible: true
type: Reaction
modifier: 578508
name: Transport [Golgi membrane]

R2295 c
modifier: 541646
is part of: http://identifiers.org/ec-code/1.14.14.1
product: 541598
modifier: 541682
name: [endoplasmic reticulum membrane]
fast: false
is: R08313
reversible: true
type: Reaction
product: 541610
reactant: 541586
is: SBO:0000176
product: 541622
reactant: 541574
modifier: 541634
reactant: 541562
modifier: 541670
modifier: 541658
reactant: 541550

387626
stoichiometry: 1.0
species: 321323
type: SpeciesReference

446286
stoichiometry: 1.0
species: 324143
type: SpeciesReference

536966
stoichiometry: 1.0
species: 351273
type: SpeciesReference

398716
stoichiometry: 1.0
species: 324643
type: SpeciesReference

482369
stoichiometry: 1.0
species: 321977
type: SpeciesReference

540302
stoichiometry: 1.0
species: 321552
type: SpeciesReference

434962
stoichiometry: 1.0
species: 321163
type: SpeciesReference

333056
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

485549
stoichiometry: 1.0
species: 321515
type: SpeciesReference

396065
stoichiometry: 1.0
species: 321879
type: SpeciesReference

563298
stoichiometry: 1.0
species: 330853
type: SpeciesReference

351357
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R984 c
is: R02019
is part of: http://identifiers.org/ec-code/1.17.4.1
reversible: false
modifier: 436198
reactant: 436114
type: Reaction
modifier: 436174
product: 436150
reactant: 436126
modifier: 436186
product: 436162
product: 436138
fast: false
name: 2'-Deoxyguanosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase [cytosol]
is: SBO:0000176

506610
stoichiometry: 1.0
species: 323333
type: SpeciesReference

510834
stoichiometry: 1.0
species: 348705
type: SpeciesReference

395177
stoichiometry: 1.0
species: 324071
type: SpeciesReference

501571
stoichiometry: 1.0
species: 327796
type: SpeciesReference

324788
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

506094
stoichiometry: 1.0
species: 353781
type: SpeciesReference

493672
stoichiometry: 1.0
species: 344804
type: SpeciesReference

434434
stoichiometry: 1.0
species: 330889
type: SpeciesReference

522316
stoichiometry: 1.0
species: 323949
type: SpeciesReference

447810
stoichiometry: 1.0
species: 333620
type: SpeciesReference

565718
stoichiometry: 2.0
species: 336439
type: SpeciesReference

405070
stoichiometry: 1.0
species: 323345
type: SpeciesReference

370527
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialinnermembrane
type: Species

326069
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

458182
stoichiometry: 1.0
species: 334604
type: SpeciesReference

391561
stoichiometry: 1.0
species: 327328
type: SpeciesReference

568730
stoichiometry: 1.0
species: 325509
type: SpeciesReference

484853
stoichiometry: 1.0
species: 322612
type: SpeciesReference

482298
stoichiometry: 1.0
species: 341225
type: SpeciesReference

R1179 c
is: SBO:0000176
reactant: 451241
name: Phenethylamine:oxygen oxidoreductase (deaminating) [mitochondrial outer membrane]
fast: false
modifier: 451289
product: 451265
reactant: 451217
is: R02613
reactant: 451229
product: 451277
type: Reaction
is part of: http://identifiers.org/ec-code/1.4.3.4
reversible: false
product: 451253

406450
stoichiometry: 1.0
species: 322415
type: SpeciesReference

328816
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

575593
stoichiometry: 1.0
species: 324473
type: SpeciesReference

372855
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

336235
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R2296 r
is: R08313
reactant: 541694
fast: false
product: 541742
modifier: 541814
reactant: 541706
product: 541754
modifier: 541802
reactant: 541718
is part of: http://identifiers.org/ec-code/1.14.14.1
type: Reaction
modifier: 541790
reversible: true
reactant: 541730
modifier: 541826
modifier: 541778
is: SBO:0000176
product: 541766
name: [endoplasmic reticulum membrane]

524226
stoichiometry: 1.0
species: 324510
type: SpeciesReference

459826
stoichiometry: 1.0
species: 322637
type: SpeciesReference

423444
stoichiometry: 1.0
species: 327640
type: SpeciesReference

R857 c
type: Reaction
fast: false
is: SBO:0000176
reactant: 426695
modifier: 426743
is: R01663
name: dCMP aminohydrolase [cytosol]
product: 426719
is part of: http://identifiers.org/ec-code/3.5.4.12
product: 426731
reactant: 426707
reversible: false

R335 p
is part of: http://identifiers.org/ec-code/1.1.1.42
reversible: true
fast: false
product: 389198
product: 389186
name: Isocitrate:NADP+ oxidoreductase (decarboxylating) [peroxisome]
is: SBO:0000176
product: 389222
product: 389210
is: R00267
type: Reaction
modifier: 389234
reactant: 389174
reactant: 389162

429023
stoichiometry: 1.0
species: 321455
type: SpeciesReference

426995
stoichiometry: 1.0
species: 328983
type: SpeciesReference

376106
stoichiometry: 1.0
species: 345548
type: SpeciesReference

475818
stoichiometry: 1.0
species: 346124
type: SpeciesReference

338982
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

427259
stoichiometry: 1.0
species: 326518
type: SpeciesReference

383234
stoichiometry: 1.0
species: 321274
type: SpeciesReference

438160
stoichiometry: 1.0
species: 321274
type: SpeciesReference

551395
stoichiometry: 1.0
species: 352605
type: SpeciesReference

525247
stoichiometry: 1.0
species: 341491
type: SpeciesReference

340406
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

467997
stoichiometry: 5.0
species: 325077
type: SpeciesReference

466893
stoichiometry: 1.0
species: 331916
type: SpeciesReference

407938
stoichiometry: 1.0
species: 324023
type: SpeciesReference

522460
stoichiometry: 1.0
species: 347601
type: SpeciesReference

407134
stoichiometry: 1.0
species: 321613
type: SpeciesReference

377295
stoichiometry: 1.0
species: 328983
type: SpeciesReference

522532
stoichiometry: 1.0
species: 348321
type: SpeciesReference

370743
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

435382
stoichiometry: 1.0
species: 335000
type: SpeciesReference

389018
stoichiometry: 1.0
species: 321540
type: SpeciesReference

567026
stoichiometry: 1.0
species: 326493
type: SpeciesReference

501355
stoichiometry: 1.0
species: 341772
type: SpeciesReference

R2825 ec
modifier: 574657
product: 574645
reactant: 574633
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

414117
stoichiometry: 1.0
species: 322244
type: SpeciesReference

R2085 c
type: Reaction
name: phospholipase D alpha 2 / PLD alpha 2 (PLDALPHA2) (PLD2) / choline phosphatase 2 [Golgi membrane]
reactant: 524793
is: R07385
product: 524819
reactant: 524780
modifier: 524844
product: 524806
modifier: 524832
is: SBO:0000176
fast: false
is part of: http://identifiers.org/ec-code/3.1.4.4
reversible: false

475458
stoichiometry: 1.0
species: 338713
type: SpeciesReference

556447
stoichiometry: 1.0
species: 325077
type: SpeciesReference

533235
stoichiometry: 1.0
species: 339382
type: SpeciesReference

349341
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

544832
stoichiometry: 1.0
species: 321540
type: SpeciesReference

335743
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

332000
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

324908
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

362215
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

493960
stoichiometry: 1.0
species: 344876
type: SpeciesReference

R461 n
is part of: http://identifiers.org/ec-code/3.6.1.15
reactant: 398428
product: 398452
name: Thiamin diphosphate phosphohydrolase [nucleus]
reactant: 398416
fast: false
type: Reaction
product: 398440
is: R00615
is: SBO:0000176
reversible: false
modifier: 398464

375266
stoichiometry: 1.0
species: 334736
type: SpeciesReference

503899
stoichiometry: 1.0
species: 353217
type: SpeciesReference

387086
stoichiometry: 1.0
species: 323321
type: SpeciesReference

366520
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

394777
stoichiometry: 1.0
species: 322832
type: SpeciesReference

361543
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

532563
stoichiometry: 1.0
species: 321236
type: SpeciesReference

493816
stoichiometry: 1.0
species: 322061
type: SpeciesReference

391250
stoichiometry: 1.0
species: 321879
type: SpeciesReference

554827
stoichiometry: 3.0
species: 334112
type: SpeciesReference

379323
stoichiometry: 2.0
species: 330709
type: SpeciesReference

334904
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

329781
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2083 c
name: aminoalcoholphosphotransferase (AAPT1) [endoplasmic reticulum membrane]
is: SBO:0000176
is part of: http://identifiers.org/ec-code/2.7.8.1
product: 524676
type: Reaction
is: R07384
reactant: 524650
product: 524689
fast: false
reversible: true
reactant: 524663
modifier: 524702

409198
stoichiometry: 1.0
species: 321613
type: SpeciesReference

497575
stoichiometry: 2.0
species: 325125
type: SpeciesReference

353829
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

502843
stoichiometry: 1.0
species: 324143
type: SpeciesReference

420324
stoichiometry: 1.0
species: 321964
type: SpeciesReference

481746
stoichiometry: 1.0
species: 321515
type: SpeciesReference

398584
stoichiometry: 1.0
species: 321163
type: SpeciesReference

383990
stoichiometry: 1.0
species: 327856
type: SpeciesReference

539990
stoichiometry: 1.0
species: 347169
type: SpeciesReference

353985
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

R1818 g
reactant: 501439
name: [Golgi membrane]
type: Reaction
modifier: 501487
product: 501451
is: R05929
product: 501463
is: SBO:0000176
reactant: 501427
reversible: true
is part of: http://identifiers.org/ec-code/2.4.1.174
fast: false
modifier: 501475

564939
stoichiometry: 1.0
species: 329632
type: SpeciesReference

453779
stoichiometry: 1.0
species: 333536
type: SpeciesReference

350277
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

R1506 m
product: 476946
product: 476934
reactant: 476898
modifier: 476958
name: S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming) [mitochondria]
is: SBO:0000176
product: 476922
type: Reaction
is part of: http://identifiers.org/ec-code/2.1.2.10
reversible: true
fast: false
is: R04125
reactant: 476910

358088
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

394561
stoichiometry: 1.0
species: 321163
type: SpeciesReference

420468
stoichiometry: 1.0
species: 324131
type: SpeciesReference

510990
stoichiometry: 1.0
species: 348717
type: SpeciesReference

353673
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

424500
stoichiometry: 1.0
species: 328324
type: SpeciesReference

576673
stoichiometry: 3.0
species: 336439
type: SpeciesReference

483365
stoichiometry: 1.0
species: 326409
type: SpeciesReference

406234
stoichiometry: 1.0
species: 325137
type: SpeciesReference

502507
stoichiometry: 1.0
species: 324131
type: SpeciesReference

518200
stoichiometry: 1.0
species: 321686
type: SpeciesReference

365119
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

359792
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialmembrane
type: Species

376647
stoichiometry: 1.0
species: 351069
type: SpeciesReference

452543
stoichiometry: 1.0
species: 333464
type: SpeciesReference

391022
stoichiometry: 1.0
species: 327148
type: SpeciesReference

419856
stoichiometry: 1.0
species: 340925
type: SpeciesReference

R1806 g
reactant: 500623
product: 500635
modifier: 500659
product: 500647
reversible: true
reactant: 500611
is: SBO:0000176
type: Reaction
is part of: http://identifiers.org/ec-code/2.4.99.3
name: [Golgi membrane]
fast: false
is: R05914

486497
stoichiometry: 1.0
species: 342764
type: SpeciesReference

R2704 ec
reversible: true
name: Transport [plasma membrane]
modifier: 568958
reactant: 568922
is: SBO:0000185
product: 568946
product: 568934
type: Reaction
reactant: 568910
fast: false

474882
stoichiometry: 1.0
species: 338568
type: SpeciesReference

368739
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

551695
stoichiometry: 1.0
species: 329370
type: SpeciesReference

459982
stoichiometry: 1.0
species: 344432
type: SpeciesReference

459118
stoichiometry: 1.0
species: 342945
type: SpeciesReference

410421
stoichiometry: 1.0
species: 325077
type: SpeciesReference

528687
stoichiometry: 1.0
species: 344888
type: SpeciesReference

568010
stoichiometry: 1.0
species: 325607
type: SpeciesReference

544100
stoichiometry: 1.0
species: 352137
type: SpeciesReference

432082
stoichiometry: 1.0
species: 329769
type: SpeciesReference

R1761 m
product: 497131
reactant: 497119
name: ethanol:cytochrome c oxidoreductase [mitochondria]
fast: false
product: 497143
is: R05198
reactant: 497107
type: Reaction
is: SBO:0000176
reversible: true

470827
stoichiometry: 1.0
species: 324980
type: SpeciesReference

447258
stoichiometry: 1.0
species: 332300
type: SpeciesReference

386822
stoichiometry: 1.0
species: 322061
type: SpeciesReference

350985
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

455926
stoichiometry: 1.0
species: 325221
type: SpeciesReference

383762
stoichiometry: 1.0
species: 321371
type: SpeciesReference

467589
stoichiometry: 1.0
species: 336739
type: SpeciesReference

R719 e
is: R01227
name: Guanosine 5'-monophosphate phosphohydrolase [plasma membrane]
reactant: 416845
fast: false
product: 416869
type: Reaction
product: 416881
is: SBO:0000176
is part of: http://identifiers.org/ec-code/3.1.3.5
reversible: false
modifier: 416893
reactant: 416857

364315
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

417504
stoichiometry: 1.0
species: 321163
type: SpeciesReference

510234
stoichiometry: 1.0
species: 348669
type: SpeciesReference

475182
stoichiometry: 1.0
species: 321588
type: SpeciesReference

332708
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

423012
stoichiometry: 1.0
species: 328120
type: SpeciesReference

414984
stoichiometry: 1.0
species: 321964
type: SpeciesReference

338835
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

532083
stoichiometry: 2.0
species: 321248
type: SpeciesReference

R1876 g
name: [Golgi]
product: 505519
reactant: 505483
is: SBO:0000176
modifier: 505531
reactant: 505495
fast: false
is part of: http://identifiers.org/ec-code/2.4.1.152
type: Reaction
is: R06025
reversible: true
product: 505507

550304
stoichiometry: 1.0
species: 321686
type: SpeciesReference

342764
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

412557
stoichiometry: 1.0
species: 321200
type: SpeciesReference

478698
stoichiometry: 1.0
species: 322503
type: SpeciesReference

539282
stoichiometry: 1.0
species: 347445
type: SpeciesReference

484421
stoichiometry: 1.0
species: 342257
type: SpeciesReference

R281 c
reactant: 384878
reversible: true
type: Reaction
fast: false
reactant: 384866
is: SBO:0000176
product: 384890
is part of: http://identifiers.org/ec-code/2.7.7.2
product: 384902
is: R00161
name: ATP:FMN adenylyltransferase [cytosol]
modifier: 384914

332852
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2013 r
name: bromobenzene-2,3-oxide hydrolase [endoplasmic reticulum membrane]
reversible: true
reactant: 517564
fast: false
is: SBO:0000176
product: 517588
type: Reaction
modifier: 517600
reactant: 517576
is part of: http://identifiers.org/ec-code/3.3.2.9
is: R07072

555499
stoichiometry: 1.0
species: 323646
type: SpeciesReference

397445
stoichiometry: 1.0
species: 321274
type: SpeciesReference

407710
stoichiometry: 1.0
species: 321163
type: SpeciesReference

570410
stoichiometry: 1.0
species: 336451
type: SpeciesReference

489029
stoichiometry: 1.0
species: 343417
type: SpeciesReference

439807
stoichiometry: 1.0
species: 337687
type: SpeciesReference

523901
stoichiometry: 1.0
species: 341345
type: SpeciesReference

567242
stoichiometry: 1.0
species: 328228
type: SpeciesReference

570626
stoichiometry: 1.0
species: 336439
type: SpeciesReference

R2901 cm
modifier: 578928
product: 578916
reactant: 578904
is: SBO:0000185
fast: false
reversible: true
name: Transport [mitochondrial membrane]
type: Reaction

R1020 c
type: Reaction
reversible: true
is: R02094
reactant: 438703
is part of: http://identifiers.org/ec-code/2.7.4.9
fast: false
name: ATP:dTMP phosphotransferase [cytosol]
modifier: 438751
reactant: 438715
product: 438739
product: 438727
is: SBO:0000176

575437
stoichiometry: 1.0
species: 336451
type: SpeciesReference

438727
stoichiometry: 1.0
species: 321783
type: SpeciesReference

323113
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

428075
stoichiometry: 1.0
species: 326310
type: SpeciesReference

549248
stoichiometry: 1.0
species: 326615
type: SpeciesReference

518356
stoichiometry: 1.0
species: 325089
type: SpeciesReference

405490
stoichiometry: 1.0
species: 322820
type: SpeciesReference

431170
stoichiometry: 1.0
species: 339310
type: SpeciesReference

R1857 r
is: R05976
reactant: 504079
fast: false
product: 504091
is: SBO:0000176
product: 504103
type: Reaction
reversible: false
name: ribophorin I family protein [endoplasmic reticulum membrane]
modifier: 504115
reactant: 504067
is part of: http://identifiers.org/ec-code/2.4.1.119

384602
stoichiometry: 1.0
species: 321274
type: SpeciesReference

415477
stoichiometry: 1.0
species: 321867
type: SpeciesReference

419964
stoichiometry: 1.0
species: 327496
type: SpeciesReference

460978
stoichiometry: 1.0
species: 325077
type: SpeciesReference

336787
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

499735
stoichiometry: 1.0
species: 321347
type: SpeciesReference

400259
stoichiometry: 1.0
species: 327784
type: SpeciesReference

346316
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2673 gc
reversible: true
product: 567170
name: Transport [Golgi membrane]
modifier: 567182
type: Reaction
product: 567158
is: SBO:0000185
reactant: 567146
reactant: 567134
fast: false

515981
stoichiometry: 1.0
species: 321613
type: SpeciesReference

510126
stoichiometry: 1.0
species: 321175
type: SpeciesReference

442399
stoichiometry: 1.0
species: 332888
type: SpeciesReference

489436
stoichiometry: 1.0
species: 321613
type: SpeciesReference

386930
stoichiometry: 1.0
species: 325125
type: SpeciesReference

351081
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialinnermembrane
type: Species

467241
stoichiometry: 1.0
species: 336547
type: SpeciesReference

326286
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

407506
stoichiometry: 1.0
species: 321927
type: SpeciesReference

325306
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

376538
stoichiometry: 1.0
species: 350649
type: SpeciesReference

523841
stoichiometry: 1.0
species: 341345
type: SpeciesReference

328923
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

R680 c
modifier: 414213
reversible: true
name: acetyl-CoA:putrescine N-acetyltransferase [cytosol]
product: 414189
is: SBO:0000176
is: R01154
product: 414201
is part of: http://identifiers.org/ec-code/2.3.1.57
reactant: 414165
type: Reaction
modifier: 414225
reactant: 414177
modifier: 414237
fast: false

R1733 m
is: R04968
reactant: 495004
reactant: 494992
product: 495028
is: SBO:0000176
fast: false
reversible: false
modifier: 495052
is part of: http://identifiers.org/ec-code/2.3.1.179
name: Tetradecanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) [mitochondrial inner membrane]
type: Reaction
product: 495016
product: 495040

353229
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

R1319 c
product: 461937
modifier: 461985
product: 461949
is: R03283
modifier: 461973
reactant: 461925
is part of: http://identifiers.org/ec-code/1.2.1.3
reactant: 461901
reversible: false
name: 4-Trimethylammoniobutanal:NAD+ 1-oxidoreductase; [cytosol]
type: Reaction
fast: false
reactant: 461913
is: SBO:0000176
product: 461961

401363
stoichiometry: 1.0
species: 325330
type: SpeciesReference

397997
stoichiometry: 1.0
species: 323513
type: SpeciesReference

344276
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

340575
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

367360
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

534830
stoichiometry: 1.0
species: 321467
type: SpeciesReference

430847
stoichiometry: 1.0
species: 333644
type: SpeciesReference

483473
stoichiometry: 1.0
species: 341554
type: SpeciesReference

R1732 c
is: SBO:0000176
reversible: false
modifier: 494968
name: Tetradecanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) [plasma membrane]
product: 494932
modifier: 494980
product: 494956
is: R04968
fast: false
type: Reaction
reactant: 494908
reactant: 494920
product: 494944
is part of: http://identifiers.org/ec-code/2.3.1.85

R2379 m
reversible: true
reactant: 548792
type: Reaction
is: SBO:0000176
reactant: 548780
fast: false
modifier: 548840
name: (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 7 isopentenyl units) [mitochondria]
is part of: http://identifiers.org/ec-code/2.5.1.91
is: R09249
product: 548804
modifier: 548828
product: 548816

394453
stoichiometry: 1.0
species: 322942
type: SpeciesReference

350877
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

399646
stoichiometry: 1.0
species: 324944
type: SpeciesReference

406342
stoichiometry: 1.0
species: 323610
type: SpeciesReference

567890
stoichiometry: 1.0
species: 336439
type: SpeciesReference

478194
stoichiometry: 1.0
species: 321783
type: SpeciesReference

R2599 cm
type: Reaction
product: 562974
is: SBO:0000185
reversible: false
reactant: 562950
modifier: 562986
product: 562962
reactant: 562938
fast: false
name: Transport [mitochondrial membrane]

346208
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

358484
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

336679
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R2382 l
fast: false
name: GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase [lysosome]
reactant: 548972
product: 549008
reactant: 548984
reversible: true
type: Reaction
modifier: 549032
is: R09295
is: SBO:0000176
is part of: http://identifiers.org/ec-code/2.4.1.221
product: 548996
modifier: 549020

474775
stoichiometry: 1.0
species: 338556
type: SpeciesReference

454894
stoichiometry: 1.0
species: 343608
type: SpeciesReference

R1546 c
modifier: 479754
is part of: http://identifiers.org/ec-code/4.1.1.45
fast: false
product: 479730
reversible: true
reactant: 479718
type: Reaction
product: 479742
is: SBO:0000176
is: R04323
name: 2-Amino-3-carboxymuconate semialdehyde carboxy-lyase [cytosol]

412077
stoichiometry: 1.0
species: 321200
type: SpeciesReference

417096
stoichiometry: 1.0
species: 333416
type: SpeciesReference

R1489 c
reactant: 475626
is part of: http://identifiers.org/ec-code/1.11.1.7
product: 475638
fast: false
reversible: false
is: SBO:0000176
is: R04007
name: Donor:hydrogen-peroxide oxidoreductase [cytosol]
type: Reaction
modifier: 475650

362635
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

452651
stoichiometry: 1.0
species: 321175
type: SpeciesReference

462741
stoichiometry: 1.0
species: 335587
type: SpeciesReference

570302
stoichiometry: 1.0
species: 325077
type: SpeciesReference

407602
stoichiometry: 1.0
species: 328839
type: SpeciesReference

325450
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

453323
stoichiometry: 1.0
species: 321163
type: SpeciesReference

572893
stoichiometry: 1.0
species: 333740
type: SpeciesReference

361699
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

331496
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

423552
stoichiometry: 1.0
species: 328276
type: SpeciesReference

339807
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

353565
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

355268
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

326178
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

414822
stoichiometry: 1.0
species: 334496
type: SpeciesReference

R2154 l
is: SBO:0000176
modifier: 529575
is part of: http://identifiers.org/ec-code/3.2.1.50
fast: false
reactant: 529539
product: 529551
reversible: false
type: Reaction
product: 529563
is: R07816
reactant: 529527
name: alpha-N-acetylglucosaminidase family / NAGLU family [lysosome]

543194
stoichiometry: 1.0
species: 327868
type: SpeciesReference

375602
stoichiometry: 1.0
species: 338059
type: SpeciesReference

R681 c
product: 414273
is: SBO:0000176
fast: false
reversible: true
is: R01156
reactant: 414261
type: Reaction
product: 414285
name: N-Acetylputrescine acetylhydrolase [cytosol]
reactant: 414249

484313
stoichiometry: 1.0
species: 325077
type: SpeciesReference

R2512 ec
product: 558067
product: 558055
reactant: 558043
reactant: 558031
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

350121
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

400859
stoichiometry: 2.0
species: 321212
type: SpeciesReference

564238
stoichiometry: 1.0
species: 331856
type: SpeciesReference

544988
stoichiometry: 1.0
species: 321698
type: SpeciesReference

503671
stoichiometry: 1.0
species: 341333
type: SpeciesReference

486077
stoichiometry: 1.0
species: 322759
type: SpeciesReference

533751
stoichiometry: 1.0
species: 322539
type: SpeciesReference

454703
stoichiometry: 1.0
species: 321467
type: SpeciesReference

384362
stoichiometry: 1.0
species: 321274
type: SpeciesReference

359012
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

497683
stoichiometry: 1.0
species: 346855
type: SpeciesReference

388298
stoichiometry: 1.0
species: 321383
type: SpeciesReference

R716 c
name: 5-methyltetrahydrofolate:NADP+ oxidoreductase [cytosol]
is: SBO:0000176
product: 416641
product: 416653
reactant: 416617
reactant: 416629
is: R01224
is part of: http://identifiers.org/ec-code/1.5.1.20
modifier: 416665
reactant: 416605
type: Reaction
reversible: false
fast: false

375050
stoichiometry: 1.0
species: 332948
type: SpeciesReference

501463
stoichiometry: 1.0
species: 353613
type: SpeciesReference

468105
stoichiometry: 1.0
species: 321163
type: SpeciesReference

481638
stoichiometry: 1.0
species: 321879
type: SpeciesReference

489137
stoichiometry: 1.0
species: 343429
type: SpeciesReference

389126
stoichiometry: 1.0
species: 322904
type: SpeciesReference

349497
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

R717 l
reactant: 416689
product: 416713
reactant: 416701
reactant: 416677
is: R01225
fast: false
product: 416725
type: Reaction
name: 5,10-Methylenetetrahydrofolate:D-alanine 2-hydroxymethyltransferase [lysosome]
is: SBO:0000176
reversible: true

337339
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

383558
stoichiometry: 1.0
species: 322061
type: SpeciesReference

562890
stoichiometry: 1.0
species: 333788
type: SpeciesReference

R1316 c
reversible: false
reactant: 461709
product: 461733
is: R03245
is part of: http://identifiers.org/ec-code/2.7.4.2
type: Reaction
fast: false
modifier: 461757
name: ATP:(R)-5-phosphomevalonate phosphotransferase [cytosol]
product: 461745
reactant: 461721
is: SBO:0000176

383342
stoichiometry: 2.0
species: 321819
type: SpeciesReference

R1807 g
is: SBO:0000176
type: Reaction
reactant: 500671
reversible: true
reactant: 500683
fast: false
product: 500707
name: [Golgi membrane]
product: 500695
is: R05915
modifier: 500719

R1431 m
name: L-Tryptophan -tRNA(Trp) ligase (AMP-forming) [mitochondria]
is part of: http://identifiers.org/ec-code/6.1.1.2
product: 470947
modifier: 470971
reversible: false
is: R03664
reactant: 470899
reactant: 470923
is: SBO:0000176
reactant: 470911
product: 470935
type: Reaction
fast: false
product: 470959

445050
stoichiometry: 1.0
species: 342909
type: SpeciesReference

578880
stoichiometry: 1.0
species: 329781
type: SpeciesReference

R306 c
is part of: http://identifiers.org/ec-code/1.1.1.40
is: SBO:0000176
product: 386966
fast: false
product: 386978
name: oxaloacetate carboxy-lyase (pyruvate-forming) [cytosol]
type: Reaction
is: R00217
modifier: 386990
reactant: 386954
reversible: true

397337
stoichiometry: 1.0
species: 326142
type: SpeciesReference

R2417 r
fast: false
modifier: 552079
reversible: true
modifier: 552091
is part of: http://identifiers.org/ec-code/2.4.1.17
is: R09426
modifier: 552115
modifier: 552151
modifier: 552127
modifier: 552067
is: SBO:0000176
name: [endoplasmic reticulum membrane]
product: 552055
product: 552043
type: Reaction
reactant: 552019
modifier: 552139
modifier: 552103
reactant: 552031

531183
stoichiometry: 1.0
species: 348357
type: SpeciesReference

492592
stoichiometry: 1.0
species: 322453
type: SpeciesReference

376214
stoichiometry: 1.0
species: 346520
type: SpeciesReference

355496
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

362791
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

R1415 c
reversible: false
product: 469568
product: 469556
reactant: 469508
reactant: 469520
product: 469544
is: R03656
fast: false
type: Reaction
is: SBO:0000176
is part of: http://identifiers.org/ec-code/6.1.1.5
modifier: 469580
reactant: 469532
name: L-Isoleucine:tRNA(Ile) ligase (AMP-forming) [cytosol]

482142
stoichiometry: 1.0
species: 321783
type: SpeciesReference

R2868 ec
fast: false
product: 577069
reactant: 577033
reactant: 577045
modifier: 577093
name: Transport [plasma membrane]
reactant: 577021
type: Reaction
product: 577081
product: 577057
is: SBO:0000185
reversible: false

558750
stoichiometry: 1.0
species: 325077
type: SpeciesReference

555067
stoichiometry: 1.0
species: 327328
type: SpeciesReference

464457
stoichiometry: 1.0
species: 324035
type: SpeciesReference

512778
stoichiometry: 1.0
species: 323937
type: SpeciesReference

R477 c
product: 399731
reactant: 399695
is: R00669
reversible: false
modifier: 399743
reactant: 399707
product: 399719
fast: false
name: N2-Acetyl-L-ornithine amidohydrolase [cytosol]
is: SBO:0000176
is part of: http://identifiers.org/ec-code/3.5.1.14
type: Reaction

484001
stoichiometry: 1.0
species: 325077
type: SpeciesReference

R2282 c
product: 540002
is part of: http://identifiers.org/ec-code/1.14.14.1
fast: false
is: SBO:0000176
is: R08293
modifier: 540050
modifier: 540014
modifier: 540062
name: [endoplasmic reticulum membrane]
reactant: 539990
modifier: 540038
reversible: true
modifier: 540026
type: Reaction

383882
stoichiometry: 1.0
species: 321443
type: SpeciesReference

537086
stoichiometry: 1.0
species: 351285
type: SpeciesReference

524650
stoichiometry: 1.0
species: 324143
type: SpeciesReference

444906
stoichiometry: 1.0
species: 321662
type: SpeciesReference

420216
stoichiometry: 1.0
species: 328660
type: SpeciesReference

376310
stoichiometry: 1.0
species: 347685
type: SpeciesReference

507258
stoichiometry: 1.0
species: 321163
type: SpeciesReference

502735
stoichiometry: 1.0
species: 353505
type: SpeciesReference

573289
stoichiometry: 1.0
species: 330174
type: SpeciesReference

554935
stoichiometry: 1.0
species: 321879
type: SpeciesReference

379215
stoichiometry: 1.0
species: 328444
type: SpeciesReference

522688
stoichiometry: 1.0
species: 349821
type: SpeciesReference

R1716 c
name: Hexanoyl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing) [plasma membrane]
is: R04955
modifier: 493684
product: 493672
type: Reaction
fast: false
is part of: http://identifiers.org/ec-code/2.3.1.85
modifier: 493696
reactant: 493636
is: SBO:0000176
reactant: 493624
reversible: true
product: 493648
product: 493660

416125
stoichiometry: 1.0
species: 322880
type: SpeciesReference

R2542 ce
modifier: 559818
reactant: 559770
name: Transport [plasma membrane]
fast: false
reactant: 559782
product: 559806
reversible: false
type: Reaction
is: SBO:0000185
product: 559794

477846
stoichiometry: 1.0
species: 345956
type: SpeciesReference

400679
stoichiometry: 1.0
species: 322013
type: SpeciesReference

529863
stoichiometry: 1.0
species: 346639
type: SpeciesReference

427367
stoichiometry: 1.0
species: 329081
type: SpeciesReference

460558
stoichiometry: 1.0
species: 340136
type: SpeciesReference

R2070 m
name: solanesyl-diphosphate:4-hydroxybenzoate nonaprenyltransferase [mitochondria]
reactant: 523757
modifier: 523793
product: 523781
is: SBO:0000176
reversible: true
is: R07273
reactant: 523745
type: Reaction
fast: false
product: 523769

391789
stoichiometry: 1.0
species: 322232
type: SpeciesReference

368979
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

575869
stoichiometry: 1.0
species: 324510
type: SpeciesReference

346819
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

538898
stoichiometry: 1.0
species: 347421
type: SpeciesReference

R11 ec
product: 374175
reactant: 374163
is: SBO:0000185
fast: false
reversible: false
name: Transport of Calcium cation [plasma membrane]
type: Reaction

461505
stoichiometry: 1.0
species: 322304
type: SpeciesReference

508650
stoichiometry: 1.0
species: 352881
type: SpeciesReference

375158
stoichiometry: 1.0
species: 333416
type: SpeciesReference

363895
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

338605
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

353421
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2426 n
is: SBO:0000176
reactant: 553063
is part of: http://identifiers.org/ec-code/3.1.2.2
reactant: 553051
reversible: true
is: R09450
product: 553075
type: Reaction
modifier: 553099
fast: false
product: 553087
name: long-chain fatty-acyl-CoA hydrolase [nucleus]

433006
stoichiometry: 1.0
species: 321600
type: SpeciesReference

362671
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

548636
stoichiometry: 1.0
species: 322527
type: SpeciesReference

423432
stoichiometry: 1.0
species: 328276
type: SpeciesReference

543050
stoichiometry: 1.0
species: 322232
type: SpeciesReference

414297
stoichiometry: 1.0
species: 321212
type: SpeciesReference

406486
stoichiometry: 1.0
species: 336631
type: SpeciesReference

325594
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

426767
stoichiometry: 1.0
species: 328959
type: SpeciesReference

484841
stoichiometry: 1.0
species: 342305
type: SpeciesReference

415525
stoichiometry: 1.0
species: 340282
type: SpeciesReference

R168 cp
product: 377943
reactant: 377931
is: SBO:0000185
fast: false
reversible: false
name: Transport of 6-Mercaptopurine [peroxisomal membrane]
type: Reaction

R705 c
product: 415933
product: 415909
fast: false
product: 415921
is: SBO:0000176
reactant: 415873
reactant: 415861
reactant: 415897
reactant: 415885
type: Reaction
name: 2-oxoglutarate:ferredoxin oxidoreductase (decarboxylating) [cytosol]
is: R01197
reversible: false

462201
stoichiometry: 1.0
species: 321248
type: SpeciesReference

342511
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

497503
stoichiometry: 1.0
species: 346783
type: SpeciesReference

446550
stoichiometry: 2.0
species: 322316
type: SpeciesReference

343211
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

376418
stoichiometry: 1.0
species: 351141
type: SpeciesReference

386918
stoichiometry: 1.0
species: 322661
type: SpeciesReference

358340
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

501583
stoichiometry: 1.0
species: 353613
type: SpeciesReference

344456
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

493660
stoichiometry: 1.0
species: 325077
type: SpeciesReference

562710
stoichiometry: 1.0
species: 333800
type: SpeciesReference

328803
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

447846
stoichiometry: 1.0
species: 321163
type: SpeciesReference

555115
stoichiometry: 1.0
species: 322880
type: SpeciesReference

R2184 m
name: [mitochondria]
reversible: true
is: SBO:0000176
product: 531723
reactant: 531699
is: R07953
fast: false
reactant: 531687
type: Reaction
modifier: 531735
product: 531711
is part of: http://identifiers.org/ec-code/2.3.1.16

372843
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

547280
stoichiometry: 1.0
species: 325077
type: SpeciesReference

R2547 ec
type: Reaction
product: 560046
modifier: 560070
product: 560058
fast: false
name: Transport [plasma membrane]
reactant: 560034
is: SBO:0000185
reactant: 560022
reversible: true

441643
stoichiometry: 1.0
species: 331399
type: SpeciesReference

326190
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

398512
stoichiometry: 1.0
species: 339334
type: SpeciesReference

326033
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

331351
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

503011
stoichiometry: 1.0
species: 324131
type: SpeciesReference

R493 m
product: 400823
is: SBO:0000176
product: 400835
product: 400811
reactant: 400775
type: Reaction
name: 3-Oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating) [mitochondria]
reactant: 400763
reactant: 400787
is part of: http://identifiers.org/ec-code/1.2.1.18
is: R00706
modifier: 400847
product: 400799
reversible: true
fast: false

454774
stoichiometry: 1.0
species: 321613
type: SpeciesReference

530247
stoichiometry: 1.0
species: 321187
type: SpeciesReference

390758
stoichiometry: 1.0
species: 323766
type: SpeciesReference

533487
stoichiometry: 1.0
species: 321964
type: SpeciesReference

R1740 m
product: 495532
reactant: 495520
type: Reaction
modifier: 495556
is: SBO:0000176
reactant: 495508
reversible: false
name: UbiE/COQ5 methyltransferase family [mitochondria]
product: 495544
is: R04983
fast: false

571909
stoichiometry: 1.0
species: 327592
type: SpeciesReference

428375
stoichiometry: 1.0
species: 325089
type: SpeciesReference

R2451 cl
modifier: 554311
fast: false
type: Reaction
reactant: 554263
name: Transport [lysosomal membrane]
product: 554299
is: SBO:0000185
reversible: true
product: 554287
reactant: 554275

335971
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

427271
stoichiometry: 1.0
species: 329448
type: SpeciesReference

444498
stoichiometry: 1.0
species: 331892
type: SpeciesReference

R1048 r
product: 440779
reactant: 440767
reactant: 440755
is: R02189
is: SBO:0000176
fast: false
reversible: true
name: Polyphosphate:D-glucose 6-phosphotransferase [endoplasmic reticulum]
type: Reaction

365191
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

570686
stoichiometry: 2.0
species: 336439
type: SpeciesReference

446274
stoichiometry: 1.0
species: 332024
type: SpeciesReference

555223
stoichiometry: 1.0
species: 327388
type: SpeciesReference

529107
stoichiometry: 1.0
species: 353745
type: SpeciesReference

390866
stoichiometry: 1.0
species: 323766
type: SpeciesReference

R1305 c
reactant: 460906
reversible: true
product: 460918
is: SBO:0000176
type: Reaction
is: R03232
reactant: 460894
name: Protein-N(pai)-phosphohistidine:sugar N(pai)-phosphotransferase [cytosol]
product: 460930
fast: false

R1109 c
product: 445602
modifier: 445674
modifier: 445662
product: 445614
modifier: 445686
fast: false
modifier: 445638
is: SBO:0000176
reactant: 445590
name: [endoplasmic reticulum membrane]
reactant: 445578
type: Reaction
product: 445626
reversible: true
is: R02356
modifier: 445650
reactant: 445566
is part of: http://identifiers.org/ec-code/1.14.14.1
reactant: 445554

565706
stoichiometry: 1.0
species: 340515
type: SpeciesReference

416245
stoichiometry: 1.0
species: 322673
type: SpeciesReference

368319
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

377235
stoichiometry: 1.0
species: 328887
type: SpeciesReference

367851
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

369459
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

448926
stoichiometry: 1.0
species: 321686
type: SpeciesReference

328396
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

322061
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

534159
stoichiometry: 1.0
species: 321879
type: SpeciesReference

365251
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

489964
stoichiometry: 2.0
species: 333524
type: SpeciesReference

516085
stoichiometry: 1.0
species: 321698
type: SpeciesReference

449454
stoichiometry: 1.0
species: 332600
type: SpeciesReference

544892
stoichiometry: 1.0
species: 321613
type: SpeciesReference

400007
stoichiometry: 1.0
species: 324980
type: SpeciesReference

467121
stoichiometry: 1.0
species: 321783
type: SpeciesReference

435358
stoichiometry: 1.0
species: 330394
type: SpeciesReference

428435
stoichiometry: 1.0
species: 332804
type: SpeciesReference

324956
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialintermembranespace
type: Species

R870 m
name: 4-methyl-2-oxopentanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating) [mitochondria]
type: Reaction
reactant: 427619
reactant: 427631
modifier: 427667
product: 427643
is: R01702
fast: false
modifier: 427679
reversible: false
product: 427655
is part of: http://identifiers.org/ec-code/1.2.4.4
is: SBO:0000176

405262
stoichiometry: 1.0
species: 329619
type: SpeciesReference

415225
stoichiometry: 1.0
species: 326931
type: SpeciesReference

430967
stoichiometry: 1.0
species: 329606
type: SpeciesReference

567878
stoichiometry: 1.0
species: 324473
type: SpeciesReference

468932
stoichiometry: 1.0
species: 327364
type: SpeciesReference

450209
stoichiometry: 1.0
species: 321212
type: SpeciesReference

560550
stoichiometry: 1.0
species: 324498
type: SpeciesReference

442819
stoichiometry: 1.0
species: 327400
type: SpeciesReference

481182
stoichiometry: 1.0
species: 341503
type: SpeciesReference

468333
stoichiometry: 1.0
species: 321686
type: SpeciesReference

R1371 c
fast: false
modifier: 466125
modifier: 466113
reactant: 466065
reactant: 466077
type: Reaction
name: Acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase [endoplasmic reticulum membrane]
product: 466101
product: 466089
is: R03437
reversible: true
is: SBO:0000176
has part: http://identifiers.org/ec-code/2.3.1.23
has part: http://identifiers.org/ec-code/2.3.1.67

544280
stoichiometry: 1.0
species: 321467
type: SpeciesReference

578808
stoichiometry: 1.0
species: 336439
type: SpeciesReference

473623
stoichiometry: 1.0
species: 345968
type: SpeciesReference

330199
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

506358
stoichiometry: 1.0
species: 353301
type: SpeciesReference

427487
stoichiometry: 1.0
species: 322097
type: SpeciesReference

453671
stoichiometry: 1.0
species: 325077
type: SpeciesReference

R2548 ec
modifier: 560106
product: 560094
reactant: 560082
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

423864
stoichiometry: 1.0
species: 321200
type: SpeciesReference

344156
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

578952
stoichiometry: 1.0
species: 336451
type: SpeciesReference

375194
stoichiometry: 1.0
species: 333812
type: SpeciesReference

R2589 mc
modifier: 562386
name: Transport [mitochondrial membrane]
fast: false
reactant: 562350
reversible: false
product: 562362
type: Reaction
product: 562374
is: SBO:0000185
reactant: 562338

496122
stoichiometry: 1.0
species: 321212
type: SpeciesReference

388178
stoichiometry: 1.0
species: 321212
type: SpeciesReference

523961
stoichiometry: 1.0
species: 328911
type: SpeciesReference

398201
stoichiometry: 1.0
species: 325137
type: SpeciesReference

507378
stoichiometry: 1.0
species: 334340
type: SpeciesReference

496880
stoichiometry: 1.0
species: 322880
type: SpeciesReference

445866
stoichiometry: 1.0
species: 322316
type: SpeciesReference

363811
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisomalmembrane
type: Species

peroxisome
is: GO:0005782
is: SBO:0000290
constant: true
size: NaN
spatial dimensions: 3.0
name: peroxisomal matrix
type: Compartment

389246
stoichiometry: 1.0
species: 343139
type: SpeciesReference

359600
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1490 c
reactant: 475674
product: 475698
modifier: 475710
reactant: 475662
name: Dodecanoyl-[acyl-carrier-protein] hydrolase [plasma membrane]
reversible: true
fast: false
product: 475686
is: R04014
type: Reaction
is part of: http://identifiers.org/ec-code/3.1.2.14
is: SBO:0000176

394525
stoichiometry: 1.0
species: 322503
type: SpeciesReference

371331
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

324606
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

441319
stoichiometry: 2.0
species: 334892
type: SpeciesReference

575749
stoichiometry: 1.0
species: 323465
type: SpeciesReference

477102
stoichiometry: 1.0
species: 321323
type: SpeciesReference

375038
stoichiometry: 1.0
species: 332912
type: SpeciesReference

501439
stoichiometry: 1.0
species: 341892
type: SpeciesReference

355376
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

390182
stoichiometry: 1.0
species: 325473
type: SpeciesReference

474571
stoichiometry: 1.0
species: 323585
type: SpeciesReference

445170
stoichiometry: 1.0
species: 321175
type: SpeciesReference

499891
stoichiometry: 1.0
species: 347973
type: SpeciesReference

R1161 l
fast: false
reversible: false
is part of: http://identifiers.org/ec-code/3.1.4.12
reactant: 449909
product: 449933
modifier: 449957
reactant: 449921
is: R02541
is: SBO:0000176
name: Sphingomyelin cholinephosphohydrolase [lysosomal membrane]
type: Reaction
product: 449945

405790
stoichiometry: 1.0
species: 321187
type: SpeciesReference

416928
stoichiometry: 1.0
species: 326310
type: SpeciesReference

517576
stoichiometry: 1.0
species: 349245
type: SpeciesReference

417192
stoichiometry: 1.0
species: 323791
type: SpeciesReference

R1791 c
fast: false
is: R05707
type: Reaction
reactant: 499387
reactant: 499399
product: 499423
is part of: http://identifiers.org/ec-code/1.5.1.30
product: 499411
is: SBO:0000176
reversible: true
modifier: 499447
product: 499435
name: reduced-riboflavin:NADP+ oxidoreductase [cytosol]

397829
stoichiometry: 1.0
species: 327364
type: SpeciesReference

468225
stoichiometry: 1.0
species: 326505
type: SpeciesReference

518500
stoichiometry: 1.0
species: 349401
type: SpeciesReference

362335
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

323345
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2395 c
product: 549920
modifier: 549944
type: Reaction
reversible: true
is: SBO:0000176
is: R09394
product: 549932
name: [cytosol]
reactant: 549908
fast: false
reactant: 549896

396989
stoichiometry: 1.0
species: 345476
type: SpeciesReference

R2078 c
reactant: 524286
product: 524310
name: Plasmenylethanolamine 2-acylhydrolase [cytosol]
reactant: 524298
is part of: http://identifiers.org/ec-code/3.1.1.4
modifier: 524347
fast: false
type: Reaction
is: R07379
modifier: 524335
is: SBO:0000176
product: 524323
reversible: true

455950
stoichiometry: 1.0
species: 322183
type: SpeciesReference

384830
stoichiometry: 1.0
species: 322527
type: SpeciesReference

453095
stoichiometry: 1.0
species: 321274
type: SpeciesReference

462393
stoichiometry: 1.0
species: 335551
type: SpeciesReference

512634
stoichiometry: 1.0
species: 323949
type: SpeciesReference

384110
stoichiometry: 1.0
species: 325912
type: SpeciesReference

455842
stoichiometry: 1.0
species: 325197
type: SpeciesReference

R70 mc
product: 375590
reactant: 375578
is: SBO:0000185
fast: false
reversible: false
name: Transport of Methylmalonate [mitochondrial membrane]
type: Reaction

323875
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

353841
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

R307 m
name: oxaloacetate carboxy-lyase (pyruvate-forming) [mitochondria]
reactant: 387002
modifier: 387050
product: 387014
modifier: 387038
has part: http://identifiers.org/ec-code/1.1.1.40
fast: false
product: 387026
is: R00217
reversible: true
is: SBO:0000176
type: Reaction
has part: http://identifiers.org/ec-code/1.1.1.38

R462 c
modifier: 398524
is: SBO:0000176
reversible: false
product: 398500
reactant: 398488
fast: false
type: Reaction
product: 398512
reactant: 398476
is: R00616
is part of: http://identifiers.org/ec-code/2.7.6.2
name: ATP:thiamine-diphosphate phosphotransferase [cytosol]

528771
stoichiometry: 1.0
species: 350757
type: SpeciesReference

470923
stoichiometry: 1.0
species: 337255
type: SpeciesReference

430271
stoichiometry: 1.0
species: 321588
type: SpeciesReference

508722
stoichiometry: 1.0
species: 352893
type: SpeciesReference

R771 e
name: Glycerol acylhydrolase [plasma membrane]
modifier: 420972
type: Reaction
is part of: http://identifiers.org/ec-code/3.1.1.34
fast: false
is: R01350
reversible: true
reactant: 420936
reactant: 420948
is: SBO:0000176
product: 420960

412005
stoichiometry: 1.0
species: 326409
type: SpeciesReference

R241 c
type: Reaction
reactant: 381999
fast: false
product: 382047
reactant: 382011
product: 382023
is: R00100
name: NADH:ferricytochrome-b5 oxidoreductase [mitochondrial outer membrane]
reversible: false
is: SBO:0000176
is part of: http://identifiers.org/ec-code/1.6.2.2
modifier: 382059
product: 382035

564963
stoichiometry: 1.0
species: 329646
type: SpeciesReference

496278
stoichiometry: 1.0
species: 345524
type: SpeciesReference

388022
stoichiometry: 1.0
species: 322808
type: SpeciesReference

558067
stoichiometry: 1.0
species: 335204
type: SpeciesReference

397937
stoichiometry: 1.0
species: 323634
type: SpeciesReference

478146
stoichiometry: 1.0
species: 341165
type: SpeciesReference

401939
stoichiometry: 1.0
species: 328792
type: SpeciesReference

497431
stoichiometry: 1.0
species: 346771
type: SpeciesReference

515931
stoichiometry: 1.0
species: 321686
type: SpeciesReference

344048
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

363703
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

554707
stoichiometry: 1.0
species: 328516
type: SpeciesReference

532503
stoichiometry: 1.0
species: 321163
type: SpeciesReference

461673
stoichiometry: 1.0
species: 340563
type: SpeciesReference

393721
stoichiometry: 1.0
species: 324824
type: SpeciesReference

354021
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

503779
stoichiometry: 1.0
species: 323718
type: SpeciesReference

496356
stoichiometry: 1.0
species: 325125
type: SpeciesReference

376563
stoichiometry: 1.0
species: 350661
type: SpeciesReference

513045
stoichiometry: 1.0
species: 348873
type: SpeciesReference

533067
stoichiometry: 1.0
species: 322025
type: SpeciesReference

517468
stoichiometry: 1.0
species: 323998
type: SpeciesReference

475338
stoichiometry: 1.0
species: 342716
type: SpeciesReference

470779
stoichiometry: 1.0
species: 322503
type: SpeciesReference

530583
stoichiometry: 1.0
species: 336643
type: SpeciesReference

473059
stoichiometry: 1.0
species: 337519
type: SpeciesReference

R1844 l
product: 503239
reactant: 503203
reversible: true
type: Reaction
is: R05963
fast: false
modifier: 503251
reactant: 503215
modifier: 503263
is part of: http://identifiers.org/ec-code/3.2.1.52
name: glycosyl hydrolase family 20 protein [lysosome]
product: 503227
is: SBO:0000176

398440
stoichiometry: 1.0
species: 321939
type: SpeciesReference

R1839 c
is: R05955
reactant: 502879
fast: false
reversible: true
type: Reaction
product: 502891
reactant: 502867
product: 502903
is: SBO:0000176
name: [cytosol]

571633
stoichiometry: 1.0
species: 324265
type: SpeciesReference

533379
stoichiometry: 1.0
species: 339721
type: SpeciesReference

358232
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

373683
stoichiometry: 1.0
species: 322710
type: SpeciesReference

323235
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

429071
stoichiometry: 1.0
species: 329396
type: SpeciesReference

362443
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

324715
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

510150
stoichiometry: 1.0
species: 348717
type: SpeciesReference

549728
stoichiometry: 1.0
species: 344624
type: SpeciesReference

553675
stoichiometry: 1.0
species: 325113
type: SpeciesReference

567146
stoichiometry: 1.0
species: 330150
type: SpeciesReference

353949
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

338922
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

469700
stoichiometry: 1.0
species: 337087
type: SpeciesReference

405682
stoichiometry: 1.0
species: 329895
type: SpeciesReference

353733
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

464409
stoichiometry: 1.0
species: 322316
type: SpeciesReference

558618
stoichiometry: 1.0
species: 326347
type: SpeciesReference

330089
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

493000
stoichiometry: 1.0
species: 344504
type: SpeciesReference

545660
stoichiometry: 1.0
species: 325125
type: SpeciesReference

R1646 p
reactant: 487589
is: SBO:0000176
modifier: 487637
is part of: http://identifiers.org/ec-code/1.3.1.38
product: 487625
name: trans-Dec-2-enoyl-CoA reductase [peroxisomal membrane]
reversible: true
fast: false
product: 487613
is: R04753
product: 487601
type: Reaction
reactant: 487577

389810
stoichiometry: 2.0
species: 321467
type: SpeciesReference

431326
stoichiometry: 1.0
species: 339527
type: SpeciesReference

478038
stoichiometry: 1.0
species: 321212
type: SpeciesReference

408034
stoichiometry: 1.0
species: 325839
type: SpeciesReference

414141
stoichiometry: 1.0
species: 332648
type: SpeciesReference

471367
stoichiometry: 1.0
species: 328923
type: SpeciesReference

R531 c
product: 403859
reversible: false
product: 403871
is: R00782
name: L-Cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming) [cytosol]
reactant: 403823
type: Reaction
reactant: 403835
product: 403847
fast: false
modifier: 403883
is: SBO:0000176
is part of: http://identifiers.org/ec-code/4.4.1.1

563692
stoichiometry: 1.0
species: 333800
type: SpeciesReference

363151
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1027 c
reactant: 439231
has part: http://identifiers.org/ec-code/3.6.1.19
modifier: 439279
product: 439255
name: dUTP nucleotidohydrolase [cytosol]
reversible: false
is: R02100
reactant: 439219
product: 439243
fast: false
type: Reaction
modifier: 439267
has part: http://identifiers.org/ec-code/3.6.1.23
is: SBO:0000176

555439
stoichiometry: 1.0
species: 326835
type: SpeciesReference

R1455 p
reactant: 472723
modifier: 472771
product: 472735
type: Reaction
product: 472747
fast: false
is: SBO:0000176
product: 472759
reversible: true
is: R03856
reactant: 472711
is part of: http://identifiers.org/ec-code/1.3.1.38
name: trans-Dodec-2-enoyl-CoA reductase [peroxisomal membrane]

398668
stoichiometry: 1.0
species: 322503
type: SpeciesReference

563394
stoichiometry: 1.0
species: 330865
type: SpeciesReference

417888
stoichiometry: 1.0
species: 327280
type: SpeciesReference

372951
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

530355
stoichiometry: 1.0
species: 321163
type: SpeciesReference

431638
stoichiometry: 1.0
species: 321323
type: SpeciesReference

510378
stoichiometry: 1.0
species: 323949
type: SpeciesReference

511890
stoichiometry: 1.0
species: 348897
type: SpeciesReference

527691
stoichiometry: 1.0
species: 322292
type: SpeciesReference

449346
stoichiometry: 1.0
species: 322453
type: SpeciesReference

339733
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

R1867 g
product: 504799
is: R05986
reversible: true
product: 504787
name: [Golgi membrane]
reactant: 504775
reactant: 504763
is part of: http://identifiers.org/ec-code/2.4.1.144
is: SBO:0000176
type: Reaction
fast: false
modifier: 504823
modifier: 504811

478614
stoichiometry: 1.0
species: 350469
type: SpeciesReference

369567
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

466173
stoichiometry: 1.0
species: 341431
type: SpeciesReference

542762
stoichiometry: 1.0
species: 347337
type: SpeciesReference

555883
stoichiometry: 1.0
species: 336439
type: SpeciesReference

427067
stoichiometry: 1.0
species: 321843
type: SpeciesReference

376983
stoichiometry: 1.0
species: 325594
type: SpeciesReference

339431
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

331242
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2329 c
name: phosphatidylcholine:retinol O-acyltransferase [endoplasmic reticulum membrane]
type: Reaction
reactant: 544460
product: 544496
is: R08389
is: SBO:0000176
modifier: 544520
product: 544484
is part of: http://identifiers.org/ec-code/2.3.1.135
fast: false
reversible: true
reactant: 544472
modifier: 544508

R2748 ge
product: 570938
reactant: 570926
is: SBO:0000185
fast: false
reversible: false
name: Transport [Golgi membrane]
type: Reaction

397589
stoichiometry: 1.0
species: 321879
type: SpeciesReference

384014
stoichiometry: 1.0
species: 321175
type: SpeciesReference

362563
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2570 cm
modifier: 561438
product: 561426
reactant: 561414
is: SBO:0000185
fast: false
reversible: true
name: Transport [mitochondrial membrane]
type: Reaction

539162
stoichiometry: 1.0
species: 321467
type: SpeciesReference

505938
stoichiometry: 1.0
species: 353265
type: SpeciesReference

423132
stoichiometry: 1.0
species: 321431
type: SpeciesReference

563484
stoichiometry: 1.0
species: 330950
type: SpeciesReference

338713
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

426875
stoichiometry: 1.0
species: 328971
type: SpeciesReference

509982
stoichiometry: 1.0
species: 321163
type: SpeciesReference

568262
stoichiometry: 1.0
species: 336451
type: SpeciesReference

536498
stoichiometry: 1.0
species: 351513
type: SpeciesReference

445422
stoichiometry: 1.0
species: 321698
type: SpeciesReference

329435
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

357572
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

435466
stoichiometry: 1.0
species: 330442
type: SpeciesReference

324800
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

405370
stoichiometry: 1.0
species: 321274
type: SpeciesReference

R682 m
is: R01157
product: 414333
fast: false
reactant: 414297
type: Reaction
reactant: 414309
is part of: http://identifiers.org/ec-code/3.5.3.11
reversible: true
modifier: 414345
product: 414321
name: Agmatine amidinohydrolase [mitochondria]
is: SBO:0000176

489856
stoichiometry: 2.0
species: 333524
type: SpeciesReference

R2005 e
is part of: http://identifiers.org/ec-code/3.1.1.4
modifier: 516881
reversible: true
modifier: 516905
name: Phosphatidylcholine 2-acylhydrolase [extracellular]
reactant: 516809
modifier: 516869
product: 516845
modifier: 516857
type: Reaction
modifier: 516893
is: R07064
is: SBO:0000176
product: 516833
reactant: 516821
fast: false

539018
stoichiometry: 1.0
species: 321248
type: SpeciesReference

R994 c
is: R02051
is part of: http://identifiers.org/ec-code/3.1.4.4
type: Reaction
product: 436846
reactant: 436834
fast: false
is: SBO:0000176
modifier: 436870
product: 436858
reactant: 436822
reversible: false
name: Phosphatidylethanolamine phosphatidohydrolase [plasma membrane]

R1488 p
is: SBO:0000176
reactant: 475566
product: 475590
is part of: http://identifiers.org/ec-code/2.3.1.16
type: Reaction
name: myristoyl-CoA:acetylCoA C-myristoyltransferase [peroxisome]
reversible: true
reactant: 475578
fast: false
is: R03991
product: 475602
modifier: 475614

523265
stoichiometry: 1.0
species: 325077
type: SpeciesReference

R2541 ec
reactant: 559722
fast: false
product: 559746
type: Reaction
reversible: false
product: 559734
modifier: 559758
is: SBO:0000185
reactant: 559710
name: Transport [plasma membrane]

343367
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

R868 m
reversible: true
modifier: 427511
is: SBO:0000176
type: Reaction
modifier: 427523
is part of: http://identifiers.org/ec-code/1.2.4.2
modifier: 427535
product: 427487
is: R01700
name: 2-oxoglutarate:[dihydrolipoyllysine-residue succinyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating) [mitochondria]
fast: false
reactant: 427463
product: 427499
reactant: 427475

403643
stoichiometry: 1.0
species: 325353
type: SpeciesReference

432586
stoichiometry: 1.0
species: 321819
type: SpeciesReference

R2577 ec
modifier: 561702
modifier: 561690
product: 561678
reactant: 561666
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

497659
stoichiometry: 1.0
species: 346807
type: SpeciesReference

495901
stoichiometry: 1.0
species: 346256
type: SpeciesReference

398740
stoichiometry: 1.0
species: 343175
type: SpeciesReference

511518
stoichiometry: 1.0
species: 348909
type: SpeciesReference

353649
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

397361
stoichiometry: 1.0
species: 324436
type: SpeciesReference

R1070 c
reversible: true
name: (5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13- dienoate D-isomerase [cytosol]
modifier: 442459
reactant: 442435
type: Reaction
is: SBO:0000176
is: R02266
is part of: http://identifiers.org/ec-code/5.3.99.2
fast: false
product: 442447

570530
stoichiometry: 1.0
species: 325101
type: SpeciesReference

407854
stoichiometry: 1.0
species: 327436
type: SpeciesReference

559566
stoichiometry: 1.0
species: 327520
type: SpeciesReference

465081
stoichiometry: 1.0
species: 341285
type: SpeciesReference

R2404 r
is: SBO:0000176
product: 550903
type: Reaction
fast: false
reactant: 550891
name: epoxide hydrolase [endoplasmic reticulum membrane]
reversible: true
modifier: 550915
is part of: http://identifiers.org/ec-code/3.3.2.9
reactant: 550880
is: R09410

426227
stoichiometry: 1.0
species: 322856
type: SpeciesReference

462837
stoichiometry: 2.0
species: 321163
type: SpeciesReference

481290
stoichiometry: 1.0
species: 341491
type: SpeciesReference

416353
stoichiometry: 1.0
species: 321431
type: SpeciesReference

335863
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

529611
stoichiometry: 1.0
species: 328252
type: SpeciesReference

R101 ec
product: 376334
reactant: 376322
is: SBO:0000185
fast: false
reversible: false
name: Transport of Androsterone glucuronide [plasma membrane]
type: Reaction

461517
stoichiometry: 1.0
species: 340563
type: SpeciesReference

R1972 c
reversible: false
fast: false
modifier: 513193
reactant: 513132
type: Reaction
name: Glutathione: 5-HPETE oxidoreductase [cytosol]
product: 513156
reactant: 513144
is: R07034
product: 513169
product: 513181
is: SBO:0000176
is part of: http://identifiers.org/ec-code/1.11.1.9

332312
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

R2760 cm
fast: false
reversible: true
product: 571537
product: 571549
reactant: 571513
is: SBO:0000185
modifier: 571561
reactant: 571525
type: Reaction
name: Transport [mitochondrial membrane]

575857
stoichiometry: 1.0
species: 323827
type: SpeciesReference

R1102 m
is: SBO:0000176
modifier: 444762
reversible: true
product: 444738
fast: false
reactant: 444714
is: R02352
product: 444726
reactant: 444702
name: Estradiol-17beta:NAD+ 17-oxidoreductase [mitochondrial inner membrane]
type: Reaction
is part of: http://identifiers.org/ec-code/1.1.1.62
product: 444750

337411
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

471583
stoichiometry: 1.0
species: 337531
type: SpeciesReference

406906
stoichiometry: 1.0
species: 322013
type: SpeciesReference

548792
stoichiometry: 1.0
species: 331700
type: SpeciesReference

551083
stoichiometry: 1.0
species: 321613
type: SpeciesReference

415897
stoichiometry: 2.0
species: 327004
type: SpeciesReference

400667
stoichiometry: 1.0
species: 321431
type: SpeciesReference

350205
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

507222
stoichiometry: 1.0
species: 341237
type: SpeciesReference

554923
stoichiometry: 1.0
species: 321783
type: SpeciesReference

572149
stoichiometry: 1.0
species: 324788
type: SpeciesReference

554143
stoichiometry: 1.0
species: 327052
type: SpeciesReference

559014
stoichiometry: 1.0
species: 326178
type: SpeciesReference

492496
stoichiometry: 1.0
species: 344228
type: SpeciesReference

R2596 cm
product: 562794
modifier: 562806
reversible: false
reactant: 562770
type: Reaction
fast: false
reactant: 562758
is: SBO:0000185
product: 562782
name: Transport [mitochondrial membrane]

424667
stoichiometry: 1.0
species: 328396
type: SpeciesReference

379227
stoichiometry: 2.0
species: 329435
type: SpeciesReference

573277
stoichiometry: 1.0
species: 325077
type: SpeciesReference

354129
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

371703
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

442111
stoichiometry: 1.0
species: 331448
type: SpeciesReference

558762
stoichiometry: 1.0
species: 332744
type: SpeciesReference

345404
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

362119
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

338071
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

395053
stoichiometry: 1.0
species: 324241
type: SpeciesReference

373467
stoichiometry: 1.0
species: 324387
type: SpeciesReference

528567
stoichiometry: 1.0
species: 350697
type: SpeciesReference

366688
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

574585
stoichiometry: 1.0
species: 321879
type: SpeciesReference

R2060 p
is: R07162
fast: false
product: 522965
type: Reaction
product: 522953
product: 522941
reactant: 522929
name: acyl-CoA:NADP+ trans-2-oxidoreductase [peroxisomal membrane]
is: SBO:0000176
is part of: http://identifiers.org/ec-code/1.3.1.38
reactant: 522917
modifier: 522977
reversible: true

482130
stoichiometry: 1.0
species: 341129
type: SpeciesReference

R1244 c
reversible: true
product: 456106
type: Reaction
product: 456118
reactant: 456094
fast: false
is part of: http://identifiers.org/ec-code/2.1.1.6
reactant: 456082
is: SBO:0000176
modifier: 456130
is: R02920
name: S-Adenosyl-L-methionine:catechol O-methyltransferase [plasma membrane]

431099
stoichiometry: 1.0
species: 321552
type: SpeciesReference

412653
stoichiometry: 1.0
species: 326518
type: SpeciesReference

459190
stoichiometry: 1.0
species: 321552
type: SpeciesReference

332972
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

367707
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

566750
stoichiometry: 1.0
species: 321783
type: SpeciesReference

517684
stoichiometry: 1.0
species: 349365
type: SpeciesReference

419352
stoichiometry: 1.0
species: 321359
type: SpeciesReference

336151
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

438086
stoichiometry: 1.0
species: 332696
type: SpeciesReference

335132
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

373311
stoichiometry: 1.0
species: 326883
type: SpeciesReference

373527
stoichiometry: 1.0
species: 323766
type: SpeciesReference

R372 p
product: 391729
reactant: 391717
reactant: 391705
product: 391753
is: R00345
product: 391741
type: Reaction
fast: false
is: SBO:0000176
reversible: true
name: phosphate:oxaloacetate carboxy-lyase (adding phosphate;phosphoenolpyruvate-forming); [peroxisome]

503179
stoichiometry: 1.0
species: 336319
type: SpeciesReference

489125
stoichiometry: 1.0
species: 321431
type: SpeciesReference

376767
stoichiometry: 1.0
species: 324083
type: SpeciesReference

368895
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R900 c
name: CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase [endoplasmic reticulum membrane]
product: 429947
type: Reaction
is part of: http://identifiers.org/ec-code/2.7.8.11
modifier: 429959
product: 429935
reactant: 429923
fast: false
reactant: 429911
is: SBO:0000176
is: R01802
reversible: false

525320
stoichiometry: 1.0
species: 339612
type: SpeciesReference

337303
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

359000
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

362899
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

R1155 e
is part of: http://identifiers.org/ec-code/1.14.17.1
is: R02535
type: Reaction
product: 449466
name: 3,4-dihydroxyphenetylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating) [plasma membrane]
product: 449454
modifier: 449478
reactant: 449430
fast: false
reactant: 449406
reversible: true
product: 449442
reactant: 449418
is: SBO:0000176

458530
stoichiometry: 1.0
species: 321383
type: SpeciesReference

437401
stoichiometry: 1.0
species: 330649
type: SpeciesReference

358688
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

539894
stoichiometry: 1.0
species: 347145
type: SpeciesReference

352353
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

563178
stoichiometry: 1.0
species: 321323
type: SpeciesReference

377391
stoichiometry: 1.0
species: 331254
type: SpeciesReference

421296
stoichiometry: 1.0
species: 322759
type: SpeciesReference

R357 e
type: Reaction
modifier: 390602
modifier: 390614
modifier: 390650
has part: http://identifiers.org/ec-code/3.6.1.6
reactant: 390554
product: 390578
name: GDP phosphohydrolase [plasma membrane]
modifier: 390590
product: 390566
reversible: false
has part: http://identifiers.org/ec-code/3.6.1.5
modifier: 390638
modifier: 390626
is: R00328
is: SBO:0000176
reactant: 390542
fast: false

336379
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

355256
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

R852 c
type: Reaction
reactant: 426383
fast: false
modifier: 426431
reactant: 426395
reversible: false
is: R01658
is: SBO:0000176
name: Dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase [cytosol]
is part of: http://identifiers.org/ec-code/2.5.1.1
product: 426407
product: 426419

511734
stoichiometry: 1.0
species: 321552
type: SpeciesReference

331460
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

384446
stoichiometry: 1.0
species: 321819
type: SpeciesReference

429935
stoichiometry: 1.0
species: 324143
type: SpeciesReference

R1208 m
is: R02723
is: SBO:0000176
modifier: 453479
reactant: 453407
product: 453443
reversible: true
reactant: 453383
product: 453431
reactant: 453419
name: [mitochondrial inner membrane]
is part of: http://identifiers.org/ec-code/1.14.15.6
product: 453455
fast: false
modifier: 453467
reactant: 453395
type: Reaction

545948
stoichiometry: 1.0
species: 349977
type: SpeciesReference

567290
stoichiometry: 1.0
species: 325113
type: SpeciesReference

332756
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

457150
stoichiometry: 1.0
species: 334328
type: SpeciesReference

349953
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

521757
stoichiometry: 1.0
species: 321383
type: SpeciesReference

325485
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

539234
stoichiometry: 1.0
species: 321613
type: SpeciesReference

368211
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

562602
stoichiometry: 1.0
species: 330853
type: SpeciesReference

R2112 c
name: DWF1 (DIMINUTO 1); catalytic [endoplasmic reticulum membrane]
modifier: 526659
product: 526635
fast: false
reactant: 526611
type: Reaction
reactant: 526623
is: R07493
reactant: 526599
product: 526647
is part of: http://identifiers.org/ec-code/1.3.1.72
is: SBO:0000176
reversible: false

382683
stoichiometry: 1.0
species: 321662
type: SpeciesReference

403427
stoichiometry: 1.0
species: 331952
type: SpeciesReference

415981
stoichiometry: 1.0
species: 330769
type: SpeciesReference

391993
stoichiometry: 1.0
species: 322880
type: SpeciesReference

346663
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

474787
stoichiometry: 1.0
species: 322612
type: SpeciesReference

550208
stoichiometry: 1.0
species: 321625
type: SpeciesReference

450341
stoichiometry: 1.0
species: 321455
type: SpeciesReference

545504
stoichiometry: 1.0
species: 321722
type: SpeciesReference

509826
stoichiometry: 1.0
species: 334304
type: SpeciesReference

361591
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

524421
stoichiometry: 1.0
species: 321187
type: SpeciesReference

326750
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

368763
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

483461
stoichiometry: 1.0
species: 321613
type: SpeciesReference

323014
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

420540
stoichiometry: 1.0
species: 327496
type: SpeciesReference

R1810 r
reversible: false
is: R05919
fast: false
type: Reaction
product: 500935
reactant: 500923
reactant: 500911
name: mannosyltransferase family [endoplasmic reticulum membrane]
modifier: 500971
modifier: 500959
is: SBO:0000176
product: 500947

367396
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

528615
stoichiometry: 2.0
species: 352185
type: SpeciesReference

478770
stoichiometry: 1.0
species: 322159
type: SpeciesReference

506466
stoichiometry: 1.0
species: 330137
type: SpeciesReference

431782
stoichiometry: 1.0
species: 324824
type: SpeciesReference

483317
stoichiometry: 1.0
species: 321843
type: SpeciesReference

R2162 c
is part of: http://identifiers.org/ec-code/3.1.1.4
reactant: 530127
product: 530139
modifier: 530163
name: [cytosol]
product: 530151
is: SBO:0000176
reactant: 530115
type: Reaction
fast: false
reversible: true
modifier: 530175
is: R07859

R1251 p
modifier: 456742
product: 456706
type: Reaction
product: 456718
reactant: 456682
reactant: 456670
reactant: 456694
name: 2-Propyn-1-al:NAD+ oxidoreductase [peroxisome]
product: 456730
is: SBO:0000176
is: R02940
is part of: http://identifiers.org/ec-code/1.2.1.3
reversible: false
fast: false

555667
stoichiometry: 1.0
species: 323646
type: SpeciesReference

328959
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

353217
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

322490
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

379455
stoichiometry: 1.0
species: 323014
type: SpeciesReference

387650
stoichiometry: 1.0
species: 321819
type: SpeciesReference

508182
stoichiometry: 1.0
species: 321903
type: SpeciesReference

456334
stoichiometry: 1.0
species: 335024
type: SpeciesReference

R2387 g
is: SBO:0000176
is part of: http://identifiers.org/ec-code/2.4.1.38
name: [Golgi membrane]
fast: false
reactant: 549332
modifier: 549392
modifier: 549404
modifier: 549416
reversible: true
is: R09299
type: Reaction
reactant: 549320
modifier: 549380
modifier: 549368
product: 549344
product: 549356

321771
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

467277
stoichiometry: 1.0
species: 336535
type: SpeciesReference

572713
stoichiometry: 1.0
species: 325101
type: SpeciesReference

440695
stoichiometry: 1.0
species: 324095
type: SpeciesReference

442891
stoichiometry: 1.0
species: 325077
type: SpeciesReference

351093
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialinnermembrane
type: Species

359720
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

461745
stoichiometry: 1.0
species: 335396
type: SpeciesReference

453899
stoichiometry: 1.0
species: 337531
type: SpeciesReference

364411
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

336031
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

347277
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

524793
stoichiometry: 1.0
species: 341700
type: SpeciesReference

392977
stoichiometry: 1.0
species: 322784
type: SpeciesReference

460294
stoichiometry: 2.0
species: 323986
type: SpeciesReference

416917
stoichiometry: 1.0
species: 327148
type: SpeciesReference

414369
stoichiometry: 1.0
species: 326883
type: SpeciesReference

358796
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialmembrane
type: Species

520848
stoichiometry: 1.0
species: 336427
type: SpeciesReference

346304
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

R1448 c
is: SBO:0000176
type: Reaction
fast: false
is part of: http://identifiers.org/ec-code/1.14.99.10
reactant: 472183
modifier: 472231
reactant: 472159
reactant: 472171
product: 472207
is: R03784
product: 472195
product: 472219
name: Pregnenolone,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating) [endoplasmic reticulum membrane]
reversible: true

352461
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

400223
stoichiometry: 1.0
species: 322673
type: SpeciesReference

474211
stoichiometry: 1.0
species: 321187
type: SpeciesReference

440767
stoichiometry: 1.0
species: 331303
type: SpeciesReference

549872
stoichiometry: 1.0
species: 352569
type: SpeciesReference

387542
stoichiometry: 1.0
species: 322759
type: SpeciesReference

344888
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialinnermembrane
type: Species

498811
stoichiometry: 1.0
species: 339200
type: SpeciesReference

376875
stoichiometry: 1.0
species: 324932
type: SpeciesReference

323125
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

411537
stoichiometry: 1.0
species: 322159
type: SpeciesReference

R1496 l
is: SBO:0000176
reactant: 476082
reversible: false
is: R04019
fast: false
type: Reaction
product: 476094
modifier: 476118
reactant: 476070
is part of: http://identifiers.org/ec-code/3.2.1.22
product: 476106
name: Digalactosylceramide galactohydrolase [lysosome]

365035
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

325377
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

495388
stoichiometry: 1.0
species: 345116
type: SpeciesReference

332864
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R41 mc
product: 374894
reactant: 374882
is: SBO:0000185
fast: false
reversible: false
name: Transport of Dihydrofolate [mitochondrial membrane]
type: Reaction

R1956 r
reactant: 511458
is part of: http://identifiers.org/ec-code/1.14.14.1
type: Reaction
is: R07021
name: 1-nitronaphthalene, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing) [endoplasmic reticulum membrane]
reversible: true
reactant: 511470
product: 511494
reactant: 511446
product: 511518
reactant: 511482
product: 511506
modifier: 511542
modifier: 511554
modifier: 511530
fast: false
modifier: 511566
is: SBO:0000176
modifier: 511578

R2101 m
modifier: 525892
product: 525880
reactant: 525868
is: R07412
is: SBO:0000176
fast: false
reversible: false
name: COX15 (CYTOCHROME C OXIDASE 15) [SP:Q9FKT8_ARATH] [mitochondrial inner membrane]
type: Reaction

475194
stoichiometry: 1.0
species: 325125
type: SpeciesReference

517792
stoichiometry: 1.0
species: 347313
type: SpeciesReference

475734
stoichiometry: 1.0
species: 338823
type: SpeciesReference

513888
stoichiometry: 1.0
species: 345644
type: SpeciesReference

550316
stoichiometry: 1.0
species: 325077
type: SpeciesReference

563588
stoichiometry: 1.0
species: 336571
type: SpeciesReference

572869
stoichiometry: 1.0
species: 327412
type: SpeciesReference

574261
stoichiometry: 1.0
species: 325101
type: SpeciesReference

532095
stoichiometry: 1.0
species: 321758
type: SpeciesReference

490036
stoichiometry: 1.0
species: 324253
type: SpeciesReference

377931
stoichiometry: 1.0
species: 338460
type: SpeciesReference

367911
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

470671
stoichiometry: 1.0
species: 337219
type: SpeciesReference

363019
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

391405
stoichiometry: 1.0
species: 321274
type: SpeciesReference

338823
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

350973
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

364303
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

347121
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

562818
stoichiometry: 1.0
species: 330950
type: SpeciesReference

383750
stoichiometry: 1.0
species: 331736
type: SpeciesReference

489532
stoichiometry: 1.0
species: 321467
type: SpeciesReference

450497
stoichiometry: 1.0
species: 327220
type: SpeciesReference

470815
stoichiometry: 1.0
species: 321274
type: SpeciesReference

432070
stoichiometry: 1.0
species: 350013
type: SpeciesReference

568046
stoichiometry: 1.0
species: 325619
type: SpeciesReference

544136
stoichiometry: 1.0
species: 352113
type: SpeciesReference

346771
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

454990
stoichiometry: 1.0
species: 321383
type: SpeciesReference

410433
stoichiometry: 1.0
species: 332768
type: SpeciesReference

473407
stoichiometry: 1.0
species: 321395
type: SpeciesReference

520380
stoichiometry: 1.0
species: 349737
type: SpeciesReference

554299
stoichiometry: 1.0
species: 329514
type: SpeciesReference

538286
stoichiometry: 1.0
species: 347373
type: SpeciesReference

350829
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

R1154 c
reactant: 449346
reactant: 449358
is part of: http://identifiers.org/ec-code/2.1.1.6
is: SBO:0000176
product: 449370
type: Reaction
name: S-Adenosyl-L-methionine:catechol O-methyltransferase [plasma membrane]
reversible: true
is: R02534
product: 449382
fast: false
modifier: 449394

332108
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

534758
stoichiometry: 1.0
species: 322588
type: SpeciesReference

339880
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

R1929 c
reactant: 508926
modifier: 508974
fast: false
is: R06871
reactant: 508938
reversible: true
product: 508950
product: 508962
type: Reaction
is: SBO:0000176
name: Phosphocholine phosphohydrolase [cytosol]
is part of: http://identifiers.org/ec-code/3.1.3.75

429863
stoichiometry: 1.0
species: 329475
type: SpeciesReference

321662
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

477966
stoichiometry: 1.0
species: 341165
type: SpeciesReference

R2071 c
modifier: 523853
reversible: true
product: 523829
fast: false
is part of: http://identifiers.org/ec-code/3.1.3.66
type: Reaction
reactant: 523805
reactant: 523817
name: 1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase [cytosol]
is: R07299
is: SBO:0000176
product: 523841

342848
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

578736
stoichiometry: 1.0
species: 329781
type: SpeciesReference

R1372 r
product: 466161
reactant: 466149
name: Acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase [endoplasmic reticulum membrane]
modifier: 466185
is: R03437
product: 466173
is part of: http://identifiers.org/ec-code/2.3.1.67
reactant: 466137
fast: false
reversible: true
is: SBO:0000176
type: Reaction

367288
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

407554
stoichiometry: 1.0
species: 324192
type: SpeciesReference

493228
stoichiometry: 1.0
species: 344672
type: SpeciesReference

R417 c
is: SBO:0000176
reversible: false
is: R00508
reactant: 395077
product: 395101
is part of: http://identifiers.org/ec-code/3.1.3.7
product: 395113
name: 3'-Phospho-5'-adenylyl sulfate 3'-phosphohydrolase [cytosol]
modifier: 395129
reactant: 395089
fast: false
type: Reaction

322280
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

R532 e
is part of: http://identifiers.org/ec-code/3.2.1.20
fast: false
is: SBO:0000176
reactant: 403895
modifier: 403943
is: R00801
type: Reaction
name: sucrose glucohydrolase [plasma membrane]
product: 403931
reactant: 403907
reversible: false
product: 403919

382790
stoichiometry: 1.0
species: 321662
type: SpeciesReference

484625
stoichiometry: 1.0
species: 342257
type: SpeciesReference

335288
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

361076
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialmembrane
type: Species

424512
stoichiometry: 1.0
species: 328768
type: SpeciesReference

345512
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

528351
stoichiometry: 1.0
species: 350661
type: SpeciesReference

463881
stoichiometry: 1.0
species: 336271
type: SpeciesReference

400955
stoichiometry: 1.0
species: 321662
type: SpeciesReference

R508 m
product: 402215
type: Reaction
product: 402227
is part of: http://identifiers.org/ec-code/1.5.1.8
is: R00716
reactant: 402179
name: N6-(L-1,3-Dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming) [mitochondria]
product: 402191
product: 402203
reactant: 402167
reactant: 402155
is: SBO:0000176
fast: false
modifier: 402239
reversible: true

R1538 m
is: SBO:0000176
fast: false
type: Reaction
product: 479214
name: 6-Lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase [mitochondria]
product: 479238
modifier: 479250
is part of: http://identifiers.org/ec-code/1.1.1.153
reversible: true
reactant: 479190
reactant: 479202
product: 479226
is: R04285

357416
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

396881
stoichiometry: 1.0
species: 345476
type: SpeciesReference

563238
stoichiometry: 1.0
species: 330853
type: SpeciesReference

R546 c
modifier: 404878
reactant: 404818
name: ATP:D-fructose 6-phosphotransferase [mitochondrial outer membrane]
product: 404830
reversible: false
product: 404842
reactant: 404806
modifier: 404866
is part of: http://identifiers.org/ec-code/2.7.1.1
fast: false
is: SBO:0000176
is: R00867
type: Reaction
modifier: 404854

529839
stoichiometry: 1.0
species: 321200
type: SpeciesReference

R2384 e
product: 549164
is part of: http://identifiers.org/ec-code/2.4.1.222
name: UDP-D-GlcNAc:O-L-fucosylpeptide 3-beta-N-acetyl-D-glucosaminyltransferase [extracellular]
fast: false
type: Reaction
modifier: 549176
is: R09296
reactant: 549128
product: 549152
reactant: 549140
is: SBO:0000176
reversible: true

496057
stoichiometry: 1.0
species: 345500
type: SpeciesReference

367635
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

420312
stoichiometry: 1.0
species: 340925
type: SpeciesReference

R869 m
name: 3-methyl-2-oxobutanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating) [mitochondria]
product: 427571
reversible: false
is: R01701
fast: false
modifier: 427607
product: 427583
modifier: 427595
is part of: http://identifiers.org/ec-code/1.2.4.4
reactant: 427547
is: SBO:0000176
reactant: 427559
type: Reaction

R672 c
name: IMP:L-aspartate ligase (GDP-forming) [cytosol]
product: 413601
modifier: 413637
modifier: 413625
is: R01135
is part of: http://identifiers.org/ec-code/6.3.4.4
product: 413589
reversible: true
type: Reaction
reactant: 413565
reactant: 413553
product: 413577
fast: false
modifier: 413613
is: SBO:0000176
reactant: 413541

404015
stoichiometry: 1.0
species: 321187
type: SpeciesReference

358052
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

527523
stoichiometry: 1.0
species: 350385
type: SpeciesReference

329154
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

454019
stoichiometry: 1.0
species: 327640
type: SpeciesReference

R1617 m
is: SBO:0000176
modifier: 485441
name: (S)-3-Hydroxyhexadecanoyl-CoA hydro-lyase [mitochondria]
product: 485405
modifier: 485465
modifier: 485429
fast: false
type: Reaction
is part of: http://identifiers.org/ec-code/4.2.1.17
reversible: true
is: R04738
modifier: 485453
reactant: 485393
product: 485417

527199
stoichiometry: 1.0
species: 350433
type: SpeciesReference

525928
stoichiometry: 1.0
species: 323585
type: SpeciesReference

R899 c
is: SBO:0000176
is part of: http://identifiers.org/ec-code/2.7.8.11
is: R01802
reversible: false
product: 429887
modifier: 429899
type: Reaction
reactant: 429851
fast: false
reactant: 429863
product: 429875
name: CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase [Golgi membrane]

391262
stoichiometry: 1.0
species: 323345
type: SpeciesReference

395489
stoichiometry: 1.0
species: 326142
type: SpeciesReference

476454
stoichiometry: 1.0
species: 338946
type: SpeciesReference

R891 r
name: alpha-D-Glucose 6-phosphate phosphohydrolase [endoplasmic reticulum membrane]
fast: false
is part of: http://identifiers.org/ec-code/3.1.3.9
reactant: 429275
is: R01788
product: 429311
product: 429299
reactant: 429287
modifier: 429323
type: Reaction
is: SBO:0000176
reversible: false

474355
stoichiometry: 1.0
species: 338374
type: SpeciesReference

532599
stoichiometry: 1.0
species: 346531
type: SpeciesReference

366532
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

575965
stoichiometry: 1.0
species: 328156
type: SpeciesReference

433846
stoichiometry: 1.0
species: 322097
type: SpeciesReference

446058
stoichiometry: 1.0
species: 332000
type: SpeciesReference

493972
stoichiometry: 1.0
species: 321467
type: SpeciesReference

428591
stoichiometry: 1.0
species: 329278
type: SpeciesReference

R608 c
reactant: 409390
product: 409426
modifier: 409474
is part of: http://identifiers.org/ec-code/1.1.1.27
name: 2-Hydroxybutyrate:NAD+ oxidoreductase [cytosol]
is: R01000
modifier: 409450
reversible: false
modifier: 409462
type: Reaction
fast: false
product: 409414
reactant: 409402
is: SBO:0000176
product: 409438

391106
stoichiometry: 1.0
species: 321879
type: SpeciesReference

523649
stoichiometry: 1.0
species: 322612
type: SpeciesReference

368655
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

362227
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

528459
stoichiometry: 1.0
species: 350685
type: SpeciesReference

452087
stoichiometry: 2.0
species: 325137
type: SpeciesReference

488981
stoichiometry: 1.0
species: 321455
type: SpeciesReference

546320
stoichiometry: 2.0
species: 321662
type: SpeciesReference

512202
stoichiometry: 1.0
species: 348969
type: SpeciesReference

508014
stoichiometry: 1.0
species: 346052
type: SpeciesReference

563022
stoichiometry: 1.0
species: 321274
type: SpeciesReference

R644 e
name: N6-D-Biotinyl-L-lysine amidohydrolase [extracellular]
reactant: 411717
fast: false
is: SBO:0000176
product: 411729
modifier: 411753
reactant: 411705
product: 411741
type: Reaction
reversible: true
is part of: http://identifiers.org/ec-code/3.5.1.12
is: R01077

352689
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

400451
stoichiometry: 1.0
species: 338593
type: SpeciesReference

371115
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

464553
stoichiometry: 1.0
species: 345956
type: SpeciesReference

493444
stoichiometry: 1.0
species: 328756
type: SpeciesReference

458686
stoichiometry: 1.0
species: 342945
type: SpeciesReference

370779
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

537542
stoichiometry: 1.0
species: 351261
type: SpeciesReference

376262
stoichiometry: 1.0
species: 347265
type: SpeciesReference

438196
stoichiometry: 1.0
species: 330853
type: SpeciesReference

488477
stoichiometry: 1.0
species: 343078
type: SpeciesReference

528243
stoichiometry: 1.0
species: 325137
type: SpeciesReference

330745
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

482669
stoichiometry: 1.0
species: 321540
type: SpeciesReference

566642
stoichiometry: 1.0
species: 321879
type: SpeciesReference

415741
stoichiometry: 1.0
species: 326518
type: SpeciesReference

481710
stoichiometry: 2.0
species: 321212
type: SpeciesReference

376118
stoichiometry: 1.0
species: 345572
type: SpeciesReference

R1544 g
product: 479622
modifier: 479646
reactant: 479610
is part of: http://identifiers.org/ec-code/2.7.8.2
reactant: 479598
is: R04321
reversible: true
type: Reaction
name: CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase [Golgi membrane]
fast: false
is: SBO:0000176
product: 479634

325245
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

329883
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

421140
stoichiometry: 1.0
species: 327664
type: SpeciesReference

426983
stoichiometry: 1.0
species: 321323
type: SpeciesReference

536906
stoichiometry: 1.0
species: 321698
type: SpeciesReference

392341
stoichiometry: 1.0
species: 323863
type: SpeciesReference

336487
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

379899
stoichiometry: 1.0
species: 321915
type: SpeciesReference

444486
stoichiometry: 999.0
species: 321187
type: SpeciesReference

428363
stoichiometry: 1.0
species: 321479
type: SpeciesReference

335983
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

390854
stoichiometry: 1.0
species: 321783
type: SpeciesReference

416257
stoichiometry: 1.0
species: 327976
type: SpeciesReference

496070
stoichiometry: 1.0
species: 321479
type: SpeciesReference

555211
stoichiometry: 1.0
species: 323585
type: SpeciesReference

446262
stoichiometry: 1.0
species: 331868
type: SpeciesReference

R2328 c
fast: false
is: SBO:0000176
reversible: true
modifier: 544448
product: 544436
is: R08388
name: all-trans-retinyl ester isomerohydrolase [plasma membrane]
product: 544424
reactant: 544412
reactant: 544400
type: Reaction

328384
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

371607
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

534147
stoichiometry: 1.0
species: 347469
type: SpeciesReference

362071
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

449442
stoichiometry: 1.0
species: 321187
type: SpeciesReference

502675
stoichiometry: 1.0
species: 346196
type: SpeciesReference

448938
stoichiometry: 1.0
species: 337591
type: SpeciesReference

326738
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

377223
stoichiometry: 1.0
species: 328552
type: SpeciesReference

555319
stoichiometry: 1.0
species: 336439
type: SpeciesReference

428423
stoichiometry: 1.0
species: 321431
type: SpeciesReference

415237
stoichiometry: 1.0
species: 322759
type: SpeciesReference

543285
stoichiometry: 1.0
species: 339539
type: SpeciesReference

324968
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

564108
stoichiometry: 1.0
species: 331856
type: SpeciesReference

567866
stoichiometry: 1.0
species: 323646
type: SpeciesReference

405250
stoichiometry: 1.0
species: 324510
type: SpeciesReference

400019
stoichiometry: 1.0
species: 322061
type: SpeciesReference

468920
stoichiometry: 1.0
species: 321274
type: SpeciesReference

489976
stoichiometry: 1.0
species: 343660
type: SpeciesReference

406318
stoichiometry: 1.0
species: 325658
type: SpeciesReference

R1075 c
reversible: true
type: Reaction
fast: false
reactant: 442651
product: 442663
is: SBO:0000176
reactant: 442639
name: N-Formimino-L-glutamate formiminohydrolase [cytosol]
product: 442675
is: R02285

414285
stoichiometry: 1.0
species: 326847
type: SpeciesReference

406474
stoichiometry: 1.0
species: 334592
type: SpeciesReference

R104 cp
product: 376406
reactant: 376394
is: SBO:0000185
fast: false
reversible: false
name: Transport of (2E,6Z,9Z,12Z,15Z,18Z)-Tetracosahexa-2,6,9,12,15,18-enoyl-CoA [peroxisomal membrane]
type: Reaction

R2293 c
reactant: 541286
is part of: http://identifiers.org/ec-code/1.14.14.1
is: R08312
modifier: 541346
modifier: 541382
product: 541310
reactant: 541262
reactant: 541274
product: 541334
product: 541322
name: [endoplasmic reticulum membrane]
fast: false
modifier: 541358
modifier: 541394
is: SBO:0000176
reactant: 541298
reversible: true
modifier: 541370
type: Reaction

426755
stoichiometry: 1.0
species: 321163
type: SpeciesReference

353433
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

558019
stoichiometry: 1.0
species: 325682
type: SpeciesReference

423420
stoichiometry: 1.0
species: 321150
type: SpeciesReference

524202
stoichiometry: 1.0
species: 338898
type: SpeciesReference

433018
stoichiometry: 1.0
species: 325137
type: SpeciesReference

336259
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

543062
stoichiometry: 1.0
species: 322942
type: SpeciesReference

459802
stoichiometry: 1.0
species: 325521
type: SpeciesReference

548648
stoichiometry: 1.0
species: 333560
type: SpeciesReference

R1631 p
reactant: 486473
name: (S)-Hydroxydecanoyl-CoA hydro-lyase [peroxisome]
is: R04744
is part of: http://identifiers.org/ec-code/4.2.1.17
product: 486485
reversible: true
product: 486497
type: Reaction
is: SBO:0000176
modifier: 486509
fast: false

408646
stoichiometry: 1.0
species: 325888
type: SpeciesReference

467409
stoichiometry: 1.0
species: 322159
type: SpeciesReference

428579
stoichiometry: 1.0
species: 325137
type: SpeciesReference

534291
stoichiometry: 1.0
species: 321783
type: SpeciesReference

415513
stoichiometry: 1.0
species: 321163
type: SpeciesReference

325582
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1845 g
name: [Golgi membrane]
modifier: 503323
is part of: http://identifiers.org/ec-code/2.4.1.88
reactant: 503275
is: R05965
is: SBO:0000176
product: 503311
fast: false
reversible: true
product: 503299
reactant: 503287
type: Reaction

501595
stoichiometry: 1.0
species: 322292
type: SpeciesReference

405094
stoichiometry: 1.0
species: 321879
type: SpeciesReference

562722
stoichiometry: 1.0
species: 330950
type: SpeciesReference

497515
stoichiometry: 2.0
species: 325089
type: SpeciesReference

342523
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

353505
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

376406
stoichiometry: 1.0
species: 351141
type: SpeciesReference

502819
stoichiometry: 1.0
species: 326627
type: SpeciesReference

446562
stoichiometry: 1.0
species: 345092
type: SpeciesReference

326045
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

344444
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

386906
stoichiometry: 1.0
species: 322097
type: SpeciesReference

R2857 ec
modifier: 576505
product: 576493
reactant: 576481
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

453395
stoichiometry: 1.0
species: 325125
type: SpeciesReference

533475
stoichiometry: 1.0
species: 338217
type: SpeciesReference

358352
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

390746
stoichiometry: 1.0
species: 321783
type: SpeciesReference

503023
stoichiometry: 1.0
species: 353469
type: SpeciesReference

530259
stoichiometry: 1.0
species: 327496
type: SpeciesReference

331363
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

555103
stoichiometry: 3.0
species: 336451
type: SpeciesReference

372831
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

547292
stoichiometry: 1.0
species: 337675
type: SpeciesReference

417744
stoichiometry: 1.0
species: 321698
type: SpeciesReference

R2125 m
is part of: http://identifiers.org/ec-code/1.8.1.4
is: R07618
modifier: 527655
fast: false
name: enzyme N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase [mitochondria]
product: 527619
type: Reaction
product: 527643
reversible: true
product: 527631
reactant: 527595
reactant: 527607
is: SBO:0000176

441631
stoichiometry: 1.0
species: 321927
type: SpeciesReference

355364
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

503659
stoichiometry: 1.0
species: 325582
type: SpeciesReference

375026
stoichiometry: 1.0
species: 332936
type: SpeciesReference

496135
stoichiometry: 1.0
species: 321431
type: SpeciesReference

462909
stoichiometry: 1.0
species: 335611
type: SpeciesReference

517588
stoichiometry: 1.0
species: 349269
type: SpeciesReference

562098
stoichiometry: 1.0
species: 328396
type: SpeciesReference

324618
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

366760
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

412797
stoichiometry: 1.0
species: 322195
type: SpeciesReference

442711
stoichiometry: 1.0
species: 325755
type: SpeciesReference

R1481 e
fast: false
product: 475134
product: 475122
reversible: true
is part of: http://identifiers.org/ec-code/1.11.1.8
reactant: 475110
is: R03973
is: SBO:0000176
name: [plasma membrane]
modifier: 475146
reactant: 475098
type: Reaction

445182
stoichiometry: 1.0
species: 321395
type: SpeciesReference

390170
stoichiometry: 1.0
species: 321783
type: SpeciesReference

519249
stoichiometry: 1.0
species: 349401
type: SpeciesReference

R137 cl
product: 377199
reactant: 377187
is: SBO:0000185
fast: false
reversible: false
name: Transport of Maltose [lysosomal membrane]
type: Reaction

362347
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialoutermembrane
type: Species

R1117 c
name: Tyramine:oxygen oxidoreductase(deaminating)(flavin-containing) [mitochondrial outer membrane]
reversible: false
is: SBO:0000176
reactant: 446358
product: 446406
fast: false
modifier: 446430
product: 446394
product: 446418
reactant: 446382
is part of: http://identifiers.org/ec-code/1.4.3.4
is: R02382
reactant: 446370
type: Reaction

323357
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

564843
stoichiometry: 1.0
species: 331820
type: SpeciesReference

469604
stoichiometry: 1.0
species: 331339
type: SpeciesReference

337207
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1355 c
type: Reaction
is: R03394
reactant: 464673
is: SBO:0000176
modifier: 464721
is part of: http://identifiers.org/ec-code/3.1.3.56
reversible: true
modifier: 464745
fast: false
reactant: 464685
name: D-myo-Inositol-1,4,5-trisphosphate 5-phosphohydrolase [cytosol]
modifier: 464733
product: 464697
modifier: 464757
modifier: 464769
product: 464709

397817
stoichiometry: 1.0
species: 322820
type: SpeciesReference

553771
stoichiometry: 2.0
species: 336439
type: SpeciesReference

332540
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

468237
stoichiometry: 1.0
species: 328276
type: SpeciesReference

417180
stoichiometry: 1.0
species: 336235
type: SpeciesReference

398889
stoichiometry: 1.0
species: 327640
type: SpeciesReference

530487
stoichiometry: 1.0
species: 322428
type: SpeciesReference

500071
stoichiometry: 1.0
species: 353385
type: SpeciesReference

441307
stoichiometry: 1.0
species: 332264
type: SpeciesReference

384230
stoichiometry: 1.0
species: 325924
type: SpeciesReference

512646
stoichiometry: 1.0
species: 348861
type: SpeciesReference

384842
stoichiometry: 1.0
species: 324313
type: SpeciesReference

R574 p
product: 406858
fast: false
name: acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase; [peroxisome]
is part of: http://identifiers.org/ec-code/2.3.1.16
reversible: false
is: R00927
is: SBO:0000176
type: Reaction
reactant: 406846
product: 406870
modifier: 406882
reactant: 406834

566738
stoichiometry: 3.0
species: 330358
type: SpeciesReference

462381
stoichiometry: 1.0
species: 321662
type: SpeciesReference

482573
stoichiometry: 1.0
species: 321236
type: SpeciesReference

560562
stoichiometry: 1.0
species: 325607
type: SpeciesReference

468345
stoichiometry: 1.0
species: 336835
type: SpeciesReference

481194
stoichiometry: 1.0
species: 321879
type: SpeciesReference

574249
stoichiometry: 1.0
species: 322207
type: SpeciesReference

344144
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

427499
stoichiometry: 1.0
species: 350769
type: SpeciesReference

R2699 cm
product: 568730
reactant: 568718
is: SBO:0000185
fast: false
reversible: false
name: Transport [mitochondrial membrane]
type: Reaction

453683
stoichiometry: 1.0
species: 336079
type: SpeciesReference

555007
stoichiometry: 1.0
species: 322588
type: SpeciesReference

578964
stoichiometry: 1.0
species: 327940
type: SpeciesReference

473611
stoichiometry: 1.0
species: 321455
type: SpeciesReference

529731
stoichiometry: 1.0
species: 324253
type: SpeciesReference

R373 c
product: 391801
reactant: 391765
reversible: true
name: 2-oxosuccinamate amidohydrolase [cytosol]
is part of: http://identifiers.org/ec-code/3.5.1.3
type: Reaction
modifier: 391813
product: 391789
is: SBO:0000176
reactant: 391777
fast: false
is: R00348

R129 cn
product: 377007
reactant: 376995
is: SBO:0000185
fast: false
reversible: false
name: Transport of L-Cysteine [nuclear membrane]
type: Reaction

523973
stoichiometry: 1.0
species: 347517
type: SpeciesReference

R2555 ec
product: 560478
reactant: 560442
fast: false
product: 560466
reactant: 560430
is: SBO:0000185
reactant: 560454
reversible: false
name: Transport [plasma membrane]
type: Reaction
product: 560490
modifier: 560502

435142
stoichiometry: 1.0
species: 321212
type: SpeciesReference

363823
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

445854
stoichiometry: 1.0
species: 331940
type: SpeciesReference

389258
stoichiometry: 1.0
species: 322061
type: SpeciesReference

524637
stoichiometry: 1.0
species: 340076
type: SpeciesReference

375182
stoichiometry: 1.0
species: 333752
type: SpeciesReference

491092
stoichiometry: 1.0
species: 325077
type: SpeciesReference

398213
stoichiometry: 1.0
species: 321758
type: SpeciesReference

394537
stoichiometry: 1.0
species: 327364
type: SpeciesReference

371343
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

R755 c
is: R01315
product: 419916
modifier: 419940
is part of: http://identifiers.org/ec-code/3.1.1.4
reactant: 419892
reactant: 419904
reversible: true
type: Reaction
product: 419928
is: SBO:0000176
fast: false
name: Phosphatidylcholine 2-acylhydrolase [endoplasmic reticulum membrane]

R2724 ec
modifier: 569846
type: Reaction
fast: false
product: 569822
product: 569834
name: Transport [plasma membrane]
reversible: true
reactant: 569810
reactant: 569798
is: SBO:0000185

359612
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

533367
stoichiometry: 1.0
species: 321964
type: SpeciesReference

384998
stoichiometry: 1.0
species: 321274
type: SpeciesReference

373695
stoichiometry: 1.0
species: 325077
type: SpeciesReference

328204
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

358244
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

575629
stoichiometry: 1.0
species: 324498
type: SpeciesReference

530595
stoichiometry: 1.0
species: 350853
type: SpeciesReference

372711
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2830 ec
product: 574909
reactant: 574897
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

475326
stoichiometry: 1.0
species: 336631
type: SpeciesReference

398452
stoichiometry: 1.0
species: 335168
type: SpeciesReference

324727
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

398105
stoichiometry: 1.0
species: 326787
type: SpeciesReference

338910
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialinnermembrane
type: Species

567158
stoichiometry: 1.0
species: 327148
type: SpeciesReference

R545 c
reactant: 404746
product: 404782
type: Reaction
name: ATP:D-fructose 1-phosphotransferase [cytosol]
reversible: true
modifier: 404794
fast: false
is: SBO:0000176
is: R00866
is part of: http://identifiers.org/ec-code/2.7.1.3
reactant: 404758
product: 404770

469712
stoichiometry: 1.0
species: 322159
type: SpeciesReference

323247
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2323 c
is part of: http://identifiers.org/ec-code/2.3.1.76
is: SBO:0000176
reactant: 544040
reactant: 544028
product: 544052
type: Reaction
is: R08381
product: 544064
fast: false
modifier: 544076
name: Palmitoyl-CoA:retinol O-acyltransferase [endoplasmic reticulum membrane]
reversible: true

453191
stoichiometry: 1.0
species: 337411
type: SpeciesReference

421128
stoichiometry: 1.0
species: 321323
type: SpeciesReference

362455
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2889 cg
modifier: 578364
reversible: true
is: SBO:0000185
fast: false
reactant: 578328
product: 578340
name: Transport [Golgi membrane]
type: Reaction
product: 578352
reactant: 578316

324400
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

R673 c
reactant: 413661
reactant: 413649
modifier: 413733
modifier: 413745
type: Reaction
modifier: 413709
modifier: 413721
is: SBO:0000176
is: R01137
is part of: http://identifiers.org/ec-code/2.7.4.6
product: 413685
product: 413673
name: ATP:dADP phosphotransferase [cytosol]
fast: false
reversible: true
modifier: 413697

400439
stoichiometry: 1.0
species: 322061
type: SpeciesReference

329007
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

415669
stoichiometry: 1.0
species: 321879
type: SpeciesReference

405694
stoichiometry: 1.0
species: 334844
type: SpeciesReference

353745
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

363163
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisomalmembrane
type: Species

421068
stoichiometry: 1.0
species: 321274
type: SpeciesReference

408046
stoichiometry: 1.0
species: 321891
type: SpeciesReference

471379
stoichiometry: 1.0
species: 332216
type: SpeciesReference

431338
stoichiometry: 1.0
species: 342884
type: SpeciesReference

329331
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

528471
stoichiometry: 1.0
species: 321503
type: SpeciesReference

323863
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

455830
stoichiometry: 1.0
species: 321274
type: SpeciesReference

R2027 c
modifier: 519353
reactant: 519210
modifier: 519340
reactant: 519249
modifier: 519314
product: 519262
reactant: 519236
modifier: 519327
type: Reaction
fast: false
reversible: true
is: SBO:0000176
name: benzo[a]pyrene-7,8-diol, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing) [endoplasmic reticulum membrane]
modifier: 519301
is: R07085
reactant: 519223
product: 519288
product: 519275
is part of: http://identifiers.org/ec-code/1.14.14.1

383474
stoichiometry: 1.0
species: 321274
type: SpeciesReference

528783
stoichiometry: 1.0
species: 328756
type: SpeciesReference

446490
stoichiometry: 1.0
species: 322966
type: SpeciesReference

508734
stoichiometry: 1.0
species: 327568
type: SpeciesReference

470911
stoichiometry: 1.0
species: 324993
type: SpeciesReference

565922
stoichiometry: 1.0
species: 321163
type: SpeciesReference

513032
stoichiometry: 1.0
species: 323998
type: SpeciesReference

353853
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

518404
stoichiometry: 1.0
species: 349389
type: SpeciesReference

454031
stoichiometry: 1.0
species: 333584
type: SpeciesReference

325695
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

388010
stoichiometry: 1.0
species: 322220
type: SpeciesReference

558055
stoichiometry: 1.0
species: 325077
type: SpeciesReference

478134
stoichiometry: 1.0
species: 339904
type: SpeciesReference

R1041 e
is part of: http://identifiers.org/ec-code/1.4.3.22
fast: false
name: 1H-Imidazole-4-ethanamine:oxygen oxidoreductase (deaminating) (copper-containing) [extracellular]
product: 440239
product: 440251
is: SBO:0000176
reactant: 440215
type: Reaction
modifier: 440263
reactant: 440203
product: 440227
is: R02150
reactant: 440191
reversible: false

481878
stoichiometry: 1.0
species: 321163
type: SpeciesReference

R349 c
is: SBO:0000176
reactant: 390050
is: R00291
is part of: http://identifiers.org/ec-code/5.1.3.2
modifier: 390074
name: UDP-glucose 4-epimerase [cytosol]
reversible: true
type: Reaction
product: 390062
fast: false

397925
stoichiometry: 1.0
species: 324534
type: SpeciesReference

497443
stoichiometry: 2.0
species: 325077
type: SpeciesReference

496343
stoichiometry: 1.0
species: 321515
type: SpeciesReference

383318
stoichiometry: 1.0
species: 321323
type: SpeciesReference

564951
stoichiometry: 1.0
species: 321783
type: SpeciesReference

363715
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R2606 mc
reactant: 563370
product: 563394
reversible: false
name: Transport [mitochondrial membrane]
modifier: 563406
fast: false
product: 563382
reactant: 563358
type: Reaction
is: SBO:0000185

401927
stoichiometry: 1.0
species: 321431
type: SpeciesReference

R566 m
name: L-Alanine:3-oxopropanoate aminotransferase [mitochondria]
is: R00907
fast: false
reactant: 406342
reactant: 406354
type: Reaction
product: 406378
is: SBO:0000176
product: 406366
reversible: true

423960
stoichiometry: 1.0
species: 338823
type: SpeciesReference

344036
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

329769
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialintermembranespace
type: Species

482681
stoichiometry: 1.0
species: 325077
type: SpeciesReference

R491 c
modifier: 400631
reversible: true
is: SBO:0000176
is part of: http://identifiers.org/ec-code/1.1.1.27
product: 400595
product: 400619
name: (S)-Lactate:NAD+ oxidoreductase [cytosol]
is: R00703
reactant: 400571
modifier: 400643
type: Reaction
reactant: 400583
product: 400607
fast: false
modifier: 400655

533055
stoichiometry: 1.0
species: 350529
type: SpeciesReference

574357
stoichiometry: 1.0
species: 334016
type: SpeciesReference

376551
stoichiometry: 1.0
species: 350661
type: SpeciesReference

492940
stoichiometry: 1.0
species: 344504
type: SpeciesReference

379395
stoichiometry: 2.0
species: 331496
type: SpeciesReference

R2140 m
type: Reaction
product: 528651
reactant: 528615
is: SBO:0000176
reversible: false
product: 528639
is: R07767
reactant: 528591
fast: false
product: 528627
name: protein N6-(octanoyl)lysine:sulfur sulfurtransferase [mitochondrial inner membrane]
is part of: http://identifiers.org/ec-code/2.8.1.8
reactant: 528603
modifier: 528663

489868
stoichiometry: 1.0
species: 343660
type: SpeciesReference

567974
stoichiometry: 1.0
species: 336439
type: SpeciesReference

453455
stoichiometry: 1.0
species: 343673
type: SpeciesReference

539006
stoichiometry: 1.0
species: 347433
type: SpeciesReference

R1630 m
fast: false
is: SBO:0000176
modifier: 486449
modifier: 486437
product: 486401
product: 486413
is part of: http://identifiers.org/ec-code/4.2.1.17
name: (S)-Hydroxydecanoyl-CoA hydro-lyase [mitochondria]
modifier: 486425
reversible: true
reactant: 486389
type: Reaction
modifier: 486461
is: R04744

357560
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

435478
stoichiometry: 1.0
species: 331592
type: SpeciesReference

554371
stoichiometry: 1.0
species: 323309
type: SpeciesReference

324812
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

432574
stoichiometry: 1.0
species: 329833
type: SpeciesReference

343355
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

514839
stoichiometry: 1.0
species: 348585
type: SpeciesReference

568142
stoichiometry: 1.0
species: 336439
type: SpeciesReference

491992
stoichiometry: 1.0
species: 344096
type: SpeciesReference

R1633 p
reactant: 486629
product: 486677
reactant: 486641
is: SBO:0000176
name: (S)-hydroxyoctanoyl-CoA:NAD+ oxidoreductase [peroxisome]
fast: false
type: Reaction
is: R04745
is part of: http://identifiers.org/ec-code/1.1.1.35
product: 486653
modifier: 486701
reversible: true
product: 486665
modifier: 486689

523253
stoichiometry: 1.0
species: 321686
type: SpeciesReference

562830
stoichiometry: 1.0
species: 333788
type: SpeciesReference

R1575 c
modifier: 482022
fast: false
reactant: 481986
reversible: true
type: Reaction
reactant: 481974
product: 481998
name: 1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase [plasma membrane]
is: R04452
is part of: http://identifiers.org/ec-code/3.1.1.47
product: 482010
is: SBO:0000176

377379
stoichiometry: 1.0
species: 331242
type: SpeciesReference

399084
stoichiometry: 1.0
species: 321515
type: SpeciesReference

570542
stoichiometry: 1.0
species: 326992
type: SpeciesReference

527091
stoichiometry: 1.0
species: 342110
type: SpeciesReference

465093
stoichiometry: 1.0
species: 321951
type: SpeciesReference

R2812 ec
product: 574105
product: 574093
reactant: 574081
reactant: 574069
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

426239
stoichiometry: 1.0
species: 328792
type: SpeciesReference

346759
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

329448
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

R2629 cm
type: Reaction
modifier: 564855
is: SBO:0000185
name: Transport [mitochondrial membrane]
fast: false
reactant: 564819
reversible: false
product: 564843
reactant: 564807
product: 564831

416365
stoichiometry: 1.0
species: 327136
type: SpeciesReference

508890
stoichiometry: 1.0
species: 321879
type: SpeciesReference

335875
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

482070
stoichiometry: 1.0
species: 341093
type: SpeciesReference

529623
stoichiometry: 1.0
species: 353757
type: SpeciesReference

462825
stoichiometry: 1.0
species: 335875
type: SpeciesReference

444594
stoichiometry: 1.0
species: 321467
type: SpeciesReference

R2415 c
name: carbonyl reductase [cytosol]
is: SBO:0000176
reactant: 551839
reactant: 551827
modifier: 551875
product: 551851
reactant: 551815
type: Reaction
modifier: 551887
is part of: http://identifiers.org/ec-code/1.1.1.184
product: 551863
is: R09420
reversible: true
fast: false

R2837 ec
product: 575197
product: 575185
reactant: 575173
reactant: 575161
is: SBO:0000185
fast: false
reversible: false
name: Transport [plasma membrane]
type: Reaction

555427
stoichiometry: 1.0
species: 323465
type: SpeciesReference

352581
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

563382
stoichiometry: 1.0
species: 328384
type: SpeciesReference

530367
stoichiometry: 1.0
species: 327496
type: SpeciesReference

342631
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

427055
stoichiometry: 1.0
species: 334532
type: SpeciesReference

555871
stoichiometry: 1.0
species: 328156
type: SpeciesReference

338059
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

R2245 r
name: [endoplasmic reticulum membrane]
type: Reaction
is: SBO:0000176
reactant: 535910
fast: false
product: 535946
modifier: 536006
modifier: 535958
modifier: 536042
reversible: true
is: R08259
reactant: 535922
modifier: 535982
product: 535934
modifier: 535994
modifier: 536030
is part of: http://identifiers.org/ec-code/2.4.1.17
modifier: 535970
modifier: 536018

411825
stoichiometry: 1.0
species: 321236
type: SpeciesReference

339721
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

376971
stoichiometry: 1.0
species: 325582
type: SpeciesReference

endoplasmicreticulum
is: GO:0005788
is: SBO:0000290
constant: true
size: NaN
spatial dimensions: 3.0
name: endoplasmic reticulum lumen
type: Compartment

487829
stoichiometry: 1.0
species: 342836
type: SpeciesReference

369579
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1183 c
type: Reaction
fast: false
reactant: 451546
is: R02630
product: 451570
product: 451558
reversible: true
is: SBO:0000176
reactant: 451533
name: Protein-N(pai)-phosphohistidine:sugar N(pai)-phosphotransferase [cytosol]

397577
stoichiometry: 1.0
species: 321783
type: SpeciesReference

499795
stoichiometry: 1.0
species: 321347
type: SpeciesReference

331254
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

568250
stoichiometry: 1.0
species: 324498
type: SpeciesReference

550436
stoichiometry: 1.0
species: 321552
type: SpeciesReference

339443
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

445434
stoichiometry: 1.0
species: 325089
type: SpeciesReference

539150
stoichiometry: 1.0
species: 347409
type: SpeciesReference

R2042 p
product: 521212
is part of: http://identifiers.org/ec-code/2.5.1.18
reactant: 521186
reversible: false
reactant: 521199
fast: false
product: 521225
is: SBO:0000176
name: 2-(S-glutathionyl)acetyl-chloride:glutathione 2-(S-glutathionyl)acetyltransferase [peroxisome]
type: Reaction
is: R07094
modifier: 521238

423144
stoichiometry: 1.0
species: 328144
type: SpeciesReference

362551
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

505926
stoichiometry: 1.0
species: 323333
type: SpeciesReference

426863
stoichiometry: 1.0
species: 321187
type: SpeciesReference

509970
stoichiometry: 1.0
species: 334292
type: SpeciesReference

338701
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

394693
stoichiometry: 1.0
species: 323887
type: SpeciesReference

412641
stoichiometry: 1.0
species: 326238
type: SpeciesReference

431087
stoichiometry: 1.0
species: 332504
type: SpeciesReference

574573
stoichiometry: 1.0
species: 321783
type: SpeciesReference

370071
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

484409
stoichiometry: 1.0
species: 321431
type: SpeciesReference

533619
stoichiometry: 1.0
species: 321274
type: SpeciesReference

335120
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

373323
stoichiometry: 1.0
species: 331327
type: SpeciesReference

R2530 cn
product: 559086
reactant: 559074
is: SBO:0000185
fast: false
reversible: true
name: Transport [nuclear membrane]
type: Reaction

493756
stoichiometry: 1.0
species: 344804
type: SpeciesReference

460078
stoichiometry: 1.0
species: 334940
type: SpeciesReference

332984
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

474499
stoichiometry: 1.0
species: 337675
type: SpeciesReference

R2409 c
modifier: 551131
product: 551071
reactant: 551035
reactant: 551047
modifier: 551107
product: 551095
reversible: true
is: SBO:0000176
modifier: 551155
product: 551083
name: [endoplasmic reticulum membrane]
reactant: 551023
fast: false
is part of: http://identifiers.org/ec-code/1.14.14.1
modifier: 551143
reactant: 551059
type: Reaction
modifier: 551119
is: R09416

362887
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

337315
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

458542
stoichiometry: 1.0
species: 342945
type: SpeciesReference

507090
stoichiometry: 1.0
species: 326033
type: SpeciesReference

389102
stoichiometry: 1.0
species: 321588
type: SpeciesReference

373539
stoichiometry: 1.0
species: 331832
type: SpeciesReference

376755
stoichiometry: 1.0
species: 324071
type: SpeciesReference

368883
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

R202 cp
product: 378759
reactant: 378747
is: SBO:0000185
fast: false
reversible: false
name: Transport of (1R,2S)-Naphthalene 1,2-oxide [peroxisomal membrane]
type: Reaction

404111
stoichiometry: 1.0
species: 338398
type: SpeciesReference

347997
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

525332
stoichiometry: 1.0
species: 324131
type: SpeciesReference

400835
stoichiometry: 1.0
species: 325125
type: SpeciesReference

352365
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

358676
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1721 c
modifier: 494092
reactant: 494044
product: 494068
is part of: http://identifiers.org/ec-code/2.3.1.85
modifier: 494104
product: 494056
name: Octanoyl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) [plasma membrane]
reactant: 494032
product: 494080
is: R04959
fast: false
is: SBO:0000176
type: Reaction
reversible: true

575845
stoichiometry: 1.0
species: 336451
type: SpeciesReference

R1482 m
is: R03989
fast: false
product: 475206
modifier: 475218
name: trans-Tetradec-2-enoyl-CoA reductase [mitochondrial inner membrane]
reactant: 475170
product: 475182
is: SBO:0000176
reactant: 475158
product: 475194
reversible: true
type: Reaction
is part of: http://identifiers.org/ec-code/1.3.1.38

551071
stoichiometry: 1.0
species: 321163
type: SpeciesReference

337423
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

R320 m
name: L-Glutamate:NADP+ oxidoreductase (deaminating) [mitochondria]
type: Reaction
product: 387950
is part of: http://identifiers.org/ec-code/1.4.1.3
is: SBO:0000176
reactant: 387902
modifier: 387974
reactant: 387890
is: R00248
product: 387926
product: 387962
modifier: 387986
reversible: true
reactant: 387914
product: 387938
fast: false

523529
stoichiometry: 1.0
species: 321686
type: SpeciesReference

512490
stoichiometry: 1.0
species: 348849
type: SpeciesReference

332324
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

330889
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

454139
stoichiometry: 1.0
species: 321163
type: SpeciesReference

R391 l
product: 393109
product: 393073
name: L-Alanine:NAD+ oxidoreductase (deaminating) [lysosome]
type: Reaction
reactant: 393049
product: 393085
reactant: 393061
is: SBO:0000176
is: R00396
reversible: true
reactant: 393037
product: 393097
fast: false

548780
stoichiometry: 7.0
species: 326664
type: SpeciesReference

415885
stoichiometry: 1.0
species: 325450
type: SpeciesReference

371715
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

354117
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

380499
stoichiometry: 1.0
species: 321927
type: SpeciesReference

573265
stoichiometry: 1.0
species: 324944
type: SpeciesReference

506790
stoichiometry: 1.0
species: 326033
type: SpeciesReference

441859
stoichiometry: 1.0
species: 331411
type: SpeciesReference

559026
stoichiometry: 1.0
species: 336451
type: SpeciesReference

554911
stoichiometry: 1.0
species: 347745
type: SpeciesReference

572137
stoichiometry: 1.0
species: 336451
type: SpeciesReference

546440
stoichiometry: 1.0
species: 352245
type: SpeciesReference

554155
stoichiometry: 1.0
species: 327028
type: SpeciesReference

350217
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

463761
stoichiometry: 1.0
species: 335887
type: SpeciesReference

568790
stoichiometry: 1.0
species: 326214
type: SpeciesReference

345416
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

395041
stoichiometry: 1.0
species: 324119
type: SpeciesReference

373479
stoichiometry: 1.0
species: 326738
type: SpeciesReference

R1616 p
product: 485333
product: 485357
product: 485345
modifier: 485369
is: R04737
reversible: true
reactant: 485321
is: SBO:0000176
is part of: http://identifiers.org/ec-code/1.1.1.35
fast: false
reactant: 485309
modifier: 485381
name: (S)-3-Hydroxyhexadecanoyl-CoA:NAD+ oxidoreductase [peroxisome]
type: Reaction

460378
stoichiometry: 1.0
species: 323051
type: SpeciesReference

R164 cr
product: 377847
reactant: 377835
is: SBO:0000185
fast: false
reversible: false
name: Transport of beta-D-Glucose 6-phosphate [endoplasmic reticulum membrane]
type: Reaction

368751
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

R867 e
modifier: 427415
reversible: false
name: (5-L-glutamyl)-peptide:taurine 5-glutamyltransferase [plasma membrane]
is part of: http://identifiers.org/ec-code/2.3.2.2
modifier: 427427
modifier: 427451
is: R01687
reactant: 427379
is: SBO:0000176
type: Reaction
modifier: 427439
product: 427403
reactant: 427367
product: 427391
fast: false

478782
stoichiometry: 1.0
species: 324143
type: SpeciesReference

367384
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

528627
stoichiometry: 2.0
species: 324800
type: SpeciesReference

493876
stoichiometry: 1.0
species: 335947
type: SpeciesReference

407410
stoichiometry: 1.0
species: 321783
type: SpeciesReference

387758
stoichiometry: 1.0
species: 322904
type: SpeciesReference

335168
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

391549
stoichiometry: 1.0
species: 321431
type: SpeciesReference

R1754 m
name: (S)-3-Hydroxyisobutyryl-CoA hydrolase [mitochondria]
reactant: 496651
modifier: 496687
reactant: 496639
product: 496663
is part of: http://identifiers.org/ec-code/3.1.2.4
fast: false
is: R05064
product: 496675
is: SBO:0000176
type: Reaction
reversible: true

524780
stoichiometry: 1.0
species: 321163
type: SpeciesReference

433942
stoichiometry: 1.0
species: 330150
type: SpeciesReference

467109
stoichiometry: 1.0
species: 336523
type: SpeciesReference

506478
stoichiometry: 1.0
species: 353301
type: SpeciesReference

431794
stoichiometry: 1.0
species: 330853
type: SpeciesReference

456490
stoichiometry: 1.0
species: 345776
type: SpeciesReference

500479
stoichiometry: 1.0
species: 353049
type: SpeciesReference

534854
stoichiometry: 1.0
species: 351777
type: SpeciesReference

508170
stoichiometry: 1.0
species: 339152
type: SpeciesReference

456346
stoichiometry: 1.0
species: 334160
type: SpeciesReference

555655
stoichiometry: 1.0
species: 323465
type: SpeciesReference

379467
stoichiometry: 1.0
species: 331472
type: SpeciesReference

328947
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

483305
stoichiometry: 1.0
species: 341503
type: SpeciesReference

365179
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

449550
stoichiometry: 1.0
species: 347193
type: SpeciesReference

353205
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

R939 n
product: 432814
fast: false
reactant: 432802
reversible: true
type: Reaction
is: R01891
name: CDP-choline:N-acylsphingosine cholinephosphotransferase [nucleus]
product: 432826
is: SBO:0000176
reactant: 432790

336043
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

347289
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1386 m
is part of: http://identifiers.org/ec-code/2.7.4.6
is: SBO:0000176
reactant: 467277
is: R03530
name: ATP:dIDP phosphotransferase [mitochondria]
modifier: 467313
type: Reaction
fast: false
product: 467289
product: 467301
reactant: 467265
reversible: true

489412
stoichiometry: 1.0
species: 352293
type: SpeciesReference

467265
stoichiometry: 1.0
species: 321323
type: SpeciesReference

321783
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R323 m
is part of: http://identifiers.org/ec-code/3.5.1.2
is: R00256
fast: false
type: Reaction
reactant: 388178
is: SBO:0000176
modifier: 388238
modifier: 388226
name: L-Glutamine amidohydrolase [mitochondria]
product: 388202
product: 388214
reversible: true
reactant: 388190

359732
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

572725
stoichiometry: 1.0
species: 336439
type: SpeciesReference

355244
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

336367
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

543170
stoichiometry: 1.0
species: 335384
type: SpeciesReference

423576
stoichiometry: 1.0
species: 330077
type: SpeciesReference

387062
stoichiometry: 1.0
species: 321359
type: SpeciesReference

356900
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

R713 m
reactant: 416365
reversible: true
is: R01218
type: Reaction
fast: false
modifier: 416401
product: 416377
name: 5,10-methylenetetrahydrofolate:NAD+ oxidoreductase [mitochondria]
reactant: 416353
is: SBO:0000176
product: 416389
is part of: http://identifiers.org/ec-code/1.5.1.15

421284
stoichiometry: 1.0
species: 330745
type: SpeciesReference

470791
stoichiometry: 1.0
species: 339273
type: SpeciesReference

R1071 r
is: SBO:0000176
product: 442483
is part of: http://identifiers.org/ec-code/5.3.99.4
reversible: true
reactant: 442471
modifier: 442495
type: Reaction
fast: false
name: (5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13- dienoate 6-isomerase [endoplasmic reticulum]
is: R02267

542606
stoichiometry: 1.0
species: 352005
type: SpeciesReference

538070
stoichiometry: 1.0
species: 321540
type: SpeciesReference

521769
stoichiometry: 1.0
species: 347253
type: SpeciesReference

545936
stoichiometry: 1.0
species: 321383
type: SpeciesReference

475878
stoichiometry: 1.0
species: 346124
type: SpeciesReference

457162
stoichiometry: 1.0
species: 321783
type: SpeciesReference

332768
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

349941
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2836 ec
product: 575149
reactant: 575137
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

R113 mc
product: 376623
reactant: 376611
is: SBO:0000185
fast: false
reversible: false
name: Transport of Lipoyl-[acp] [mitochondrial membrane]
type: Reaction

491704
stoichiometry: 1.0
species: 321686
type: SpeciesReference

384458
stoichiometry: 1.0
species: 324884
type: SpeciesReference

511746
stoichiometry: 1.0
species: 321698
type: SpeciesReference

R960 c
fast: false
modifier: 434350
name: ATP:D-glucosamine 6-phosphotransferase [mitochondrial outer membrane]
modifier: 434338
reversible: false
is: SBO:0000176
product: 434314
is part of: http://identifiers.org/ec-code/2.7.1.1
product: 434302
type: Reaction
reactant: 434278
modifier: 434326
is: R01961
reactant: 434290

331472
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

429947
stoichiometry: 1.0
species: 335899
type: SpeciesReference

R1964 p
type: Reaction
is: R07024
fast: false
name: 1-nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene glutathione-lyase (epoxide-forming) [peroxisome]
is part of: http://identifiers.org/ec-code/2.5.1.18
reversible: false
reactant: 512442
is: SBO:0000176
reactant: 512430
modifier: 512466
product: 512454

403439
stoichiometry: 1.0
species: 321540
type: SpeciesReference

382695
stoichiometry: 1.0
species: 325125
type: SpeciesReference

323027
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

370659
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

R1543 p
product: 479574
name: 1-Acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase [peroxisomal membrane]
is: R04311
is: SBO:0000176
fast: false
is part of: http://identifiers.org/ec-code/2.5.1.26
modifier: 479586
product: 479562
reactant: 479550
type: Reaction
reactant: 479538
reversible: true

368223
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

434302
stoichiometry: 1.0
species: 321783
type: SpeciesReference

325473
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

528027
stoichiometry: 1.0
species: 350637
type: SpeciesReference

482238
stoichiometry: 1.0
species: 340431
type: SpeciesReference

562614
stoichiometry: 1.0
species: 330950
type: SpeciesReference

575521
stoichiometry: 1.0
species: 336451
type: SpeciesReference

387866
stoichiometry: 1.0
species: 325125
type: SpeciesReference

539222
stoichiometry: 1.0
species: 321163
type: SpeciesReference

510702
stoichiometry: 1.0
species: 348825
type: SpeciesReference

R132 cn
product: 377079
reactant: 377067
is: SBO:0000185
fast: false
reversible: false
name: Transport of CDP [nuclear membrane]
type: Reaction

509814
stoichiometry: 1.0
species: 325089
type: SpeciesReference

430259
stoichiometry: 1.0
species: 329554
type: SpeciesReference

474799
stoichiometry: 1.0
species: 346364
type: SpeciesReference

441931
stoichiometry: 1.0
species: 323537
type: SpeciesReference

346651
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

450353
stoichiometry: 1.0
species: 332672
type: SpeciesReference

564326
stoichiometry: 1.0
species: 328396
type: SpeciesReference

568034
stoichiometry: 1.0
species: 324473
type: SpeciesReference

346905
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

R1028 c
is part of: http://identifiers.org/ec-code/2.1.1.45
fast: false
reactant: 439303
name: 5,10-Methylenetetrahydrofolate:dUMP C-methyltransferase [cytosol]
product: 439315
reactant: 439291
product: 439327
is: R02101
type: Reaction
is: SBO:0000176
reversible: true
modifier: 439339

544124
stoichiometry: 1.0
species: 325089
type: SpeciesReference

R1169 m
product: 450605
reversible: false
product: 450593
reactant: 450545
reactant: 450557
is part of: http://identifiers.org/ec-code/1.2.1.8
product: 450581
name: p-cumic alcohol:NAD+ oxidoreductase [mitochondria]
fast: false
is: SBO:0000176
reactant: 450569
modifier: 450617
type: Reaction
is: R02565

418824
stoichiometry: 1.0
species: 327424
type: SpeciesReference

475098
stoichiometry: 1.0
species: 335096
type: SpeciesReference

R501 c
is: SBO:0000176
product: 401603
modifier: 401615
is: R00711
reversible: true
modifier: 401627
reactant: 401543
type: Reaction
reactant: 401555
reactant: 401567
product: 401579
product: 401591
fast: false
name: Acetaldehyde:NADP+ oxidoreductase [cytosol]
is part of: http://identifiers.org/ec-code/1.2.1.5

350961
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

484829
stoichiometry: 1.0
species: 322478
type: SpeciesReference

347133
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

440551
stoichiometry: 1.0
species: 331254
type: SpeciesReference

467565
stoichiometry: 1.0
species: 321467
type: SpeciesReference

350817
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

563575
stoichiometry: 1.0
species: 331880
type: SpeciesReference

398309
stoichiometry: 1.0
species: 323465
type: SpeciesReference

477978
stoichiometry: 1.0
species: 321528
type: SpeciesReference

407566
stoichiometry: 1.0
species: 325755
type: SpeciesReference

321674
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

429875
stoichiometry: 1.0
species: 324143
type: SpeciesReference

534746
stoichiometry: 1.0
species: 341528
type: SpeciesReference

R530 c
reversible: true
type: Reaction
reactant: 403763
is part of: http://identifiers.org/ec-code/2.6.1.16
name: L-glutamine:D-fructose-6-phosphate isomerase (deaminating); [cytosol]
product: 403799
modifier: 403811
is: SBO:0000176
fast: false
reactant: 403775
is: R00768
product: 403787

420444
stoichiometry: 1.0
species: 329907
type: SpeciesReference

361064
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

335276
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

484613
stoichiometry: 1.0
species: 321662
type: SpeciesReference

367276
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

506586
stoichiometry: 1.0
species: 330137
type: SpeciesReference

428207
stoichiometry: 1.0
species: 329214
type: SpeciesReference

400235
stoichiometry: 1.0
species: 325053
type: SpeciesReference

415453
stoichiometry: 1.0
species: 321150
type: SpeciesReference

352473
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

393913
stoichiometry: 1.0
species: 322013
type: SpeciesReference

493216
stoichiometry: 1.0
species: 323465
type: SpeciesReference

440779
stoichiometry: 999.0
species: 333548
type: SpeciesReference

390014
stoichiometry: 1.0
species: 323076
type: SpeciesReference

474223
stoichiometry: 1.0
species: 338337
type: SpeciesReference

414357
stoichiometry: 1.0
species: 322453
type: SpeciesReference

358784
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

416905
stoichiometry: 1.0
species: 322159
type: SpeciesReference

R1012 p
reactant: 438123
fast: false
reactant: 438111
product: 438148
type: Reaction
is: R02089
is: SBO:0000176
reversible: true
product: 438136
name: ATP:deoxyadenosine 5'-phosphotransferase [peroxisome]

365023
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

325365
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

438703
stoichiometry: 1.0
species: 321274
type: SpeciesReference

R1085 m
product: 443383
type: Reaction
fast: false
product: 443359
reactant: 443335
reversible: true
is: R02315
product: 443371
reactant: 443323
reactant: 443311
is: SBO:0000176
product: 443347
name: N6-(L-1,3-Dicarboxypropyl)-L-lysine:NADP+ oxidoreductase [mitochondria]

338810
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

R1313 c
is: SBO:0000176
modifier: 461541
fast: false
reversible: true
type: Reaction
is part of: http://identifiers.org/ec-code/2.7.1.11
reactant: 461493
name: UTP:D-Tagatose 6-phosphate 1-phosphotransferase [plasma membrane]
is: R03238
reactant: 461481
product: 461517
product: 461505
modifier: 461529

387530
stoichiometry: 1.0
species: 322539
type: SpeciesReference

575413
stoichiometry: 1.0
species: 324546
type: SpeciesReference

R115 cn
product: 376671
reactant: 376659
is: SBO:0000185
fast: false
reversible: false
name: Transport of UDP [nuclear membrane]
type: Reaction

411525
stoichiometry: 1.0
species: 326310
type: SpeciesReference

376863
stoichiometry: 1.0
species: 324872
type: SpeciesReference

R2862 ec
reactant: 576721
modifier: 576769
reversible: true
reactant: 576733
type: Reaction
product: 576757
is: SBO:0000185
name: Transport [plasma membrane]
product: 576745
fast: false

431194
stoichiometry: 1.0
species: 339515
type: SpeciesReference

R596 c
is: SBO:0000176
name: ATP:uridine 5'-phosphotransferase [cytosol]
modifier: 408598
modifier: 408586
reactant: 408526
product: 408562
modifier: 408574
is part of: http://identifiers.org/ec-code/2.7.1.48
type: Reaction
is: R00964
reactant: 408538
modifier: 408610
product: 408550
fast: false
reversible: false

475722
stoichiometry: 1.0
species: 324059
type: SpeciesReference

332876
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

545828
stoichiometry: 1.0
species: 328240
type: SpeciesReference

R2151 l
is: R07813
name: [lysosome]
reactant: 529347
reactant: 529335
product: 529359
is part of: http://identifiers.org/ec-code/3.2.1.76
type: Reaction
is: SBO:0000176
product: 529371
reversible: true
fast: false
modifier: 529383

363007
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

R2310 c
product: 542966
is: R08347
is: SBO:0000176
fast: false
name: Demethylcitalopram:oxygen oxidoreductase(deaminating)(flavin-containing) [mitochondrial outer membrane]
product: 542978
reactant: 542930
is part of: http://identifiers.org/ec-code/1.4.3.4
reactant: 542954
reversible: true
modifier: 543002
reactant: 542942
type: Reaction
product: 542990

347061
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

336691
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

470683
stoichiometry: 1.0
species: 322183
type: SpeciesReference

543381
stoichiometry: 1.0
species: 339564
type: SpeciesReference

527679
stoichiometry: 1.0
species: 353949
type: SpeciesReference

342740
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

367923
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

550328
stoichiometry: 1.0
species: 347073
type: SpeciesReference

485789
stoichiometry: 1.0
species: 321248
type: SpeciesReference

377943
stoichiometry: 1.0
species: 338472
type: SpeciesReference

417036
stoichiometry: 1.0
species: 327148
type: SpeciesReference

490024
stoichiometry: 1.0
species: 346076
type: SpeciesReference

566306
stoichiometry: 1.0
species: 349125
type: SpeciesReference

371127
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

506898
stoichiometry: 1.0
species: 353817
type: SpeciesReference

521472
stoichiometry: 1.0
species: 349773
type: SpeciesReference

464541
stoichiometry: 1.0
species: 322013
type: SpeciesReference

508002
stoichiometry: 1.0
species: 321187
type: SpeciesReference

563010
stoichiometry: 1.0
species: 326738
type: SpeciesReference

452099
stoichiometry: 2.0
species: 333776
type: SpeciesReference

546332
stoichiometry: 1.0
species: 352233
type: SpeciesReference

488993
stoichiometry: 1.0
species: 343392
type: SpeciesReference

523109
stoichiometry: 1.0
species: 325077
type: SpeciesReference

376274
stoichiometry: 1.0
species: 347661
type: SpeciesReference

370767
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

368331
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

567002
stoichiometry: 1.0
species: 326505
type: SpeciesReference

539378
stoichiometry: 1.0
species: 321613
type: SpeciesReference

493432
stoichiometry: 1.0
species: 322097
type: SpeciesReference

493648
stoichiometry: 1.0
species: 321467
type: SpeciesReference

566630
stoichiometry: 1.0
species: 326409
type: SpeciesReference

362779
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

441703
stoichiometry: 1.0
species: 333332
type: SpeciesReference

488489
stoichiometry: 1.0
species: 321783
type: SpeciesReference

438184
stoichiometry: 1.0
species: 321783
type: SpeciesReference

528255
stoichiometry: 1.0
species: 350637
type: SpeciesReference

473071
stoichiometry: 1.0
species: 322037
type: SpeciesReference

331580
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

392209
stoichiometry: 1.0
species: 321248
type: SpeciesReference

330733
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

392353
stoichiometry: 2.0
species: 325125
type: SpeciesReference

336475
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

574465
stoichiometry: 1.0
species: 332864
type: SpeciesReference

379887
stoichiometry: 1.0
species: 321807
type: SpeciesReference

R1215 c
reactant: 453935
is: R02746
fast: false
reversible: true
is part of: http://identifiers.org/ec-code/3.1.1.5
is: SBO:0000176
name: 1-Acyl-sn-glycero-3-phosphocholine acylhydrolase [endoplasmic reticulum membrane]
product: 453959
reactant: 453923
modifier: 453983
product: 453947
modifier: 453971
type: Reaction

485561
stoichiometry: 1.0
species: 342415
type: SpeciesReference

454619
stoichiometry: 2.0
species: 323949
type: SpeciesReference

325233
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

R394 p
reversible: true
product: 393313
fast: false
type: Reaction
is: SBO:0000176
name: Succinate:(acceptor) oxidoreductase [peroxisome]
is: R00408
product: 393301
reactant: 393289
reactant: 393277

323138
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

347889
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

357404
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

353961
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

487601
stoichiometry: 1.0
species: 321600
type: SpeciesReference

496291
stoichiometry: 1.0
species: 321528
type: SpeciesReference

345524
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

400943
stoichiometry: 2.0
species: 321212
type: SpeciesReference

572029
stoichiometry: 1.0
species: 327556
type: SpeciesReference

446118
stoichiometry: 1.0
species: 332000
type: SpeciesReference

468380
stoichiometry: 1.0
species: 321686
type: SpeciesReference

358064
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

420300
stoichiometry: 1.0
species: 323537
type: SpeciesReference

527535
stoichiometry: 1.0
species: 350457
type: SpeciesReference

457594
stoichiometry: 1.0
species: 334448
type: SpeciesReference

329166
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

350109
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

367623
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

329870
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R1156 c
reactant: 449502
product: 449550
reactant: 449514
reactant: 449490
product: 449526
name: Phenylacetaldehyde:NAD+ oxidoreductase [cytosol]
is: SBO:0000176
is: R02536
modifier: 449574
fast: false
is part of: http://identifiers.org/ec-code/1.2.1.5
product: 449538
type: Reaction
reversible: true
modifier: 449562

426011
stoichiometry: 1.0
species: 325269
type: SpeciesReference

481722
stoichiometry: 1.0
species: 321431
type: SpeciesReference

354009
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

506682
stoichiometry: 1.0
species: 352833
type: SpeciesReference

R2169 p
fast: false
product: 530667
reversible: false
product: 530655
reactant: 530631
modifier: 530691
is: R07896
type: Reaction
modifier: 530679
reactant: 530643
name: ACX3 (ACYL-COA OXIDASE 3); acyl-CoA oxidase [peroxisome]
is: SBO:0000176
is part of: http://identifiers.org/ec-code/1.3.3.6

516098
stoichiometry: 1.0
species: 325089
type: SpeciesReference

R1295 n
reversible: true
reactant: 460294
product: 460330
is: SBO:0000176
modifier: 460366
reactant: 460306
is part of: http://identifiers.org/ec-code/1.11.1.12
type: Reaction
is: R03167
fast: false
product: 460318
modifier: 460354
name: glutathione:lipid-hydroperoxide oxidoreductase [nucleus]
product: 460342

532587
stoichiometry: 1.0
species: 322025
type: SpeciesReference

363607
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

525916
stoichiometry: 1.0
species: 350289
type: SpeciesReference

474343
stoichiometry: 1.0
species: 321274
type: SpeciesReference

438073
stoichiometry: 1.0
species: 321903
type: SpeciesReference

419232
stoichiometry: 1.0
species: 327424
type: SpeciesReference

515919
stoichiometry: 1.0
species: 321540
type: SpeciesReference

391118
stoichiometry: 1.0
species: 323345
type: SpeciesReference

R1064 r
reactant: 442051
is: SBO:0000176
fast: false
is part of: http://identifiers.org/ec-code/2.3.1.51
is: R02241
type: Reaction
reactant: 442039
modifier: 442087
product: 442075
reversible: false
name: acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase [endoplasmic reticulum membrane]
product: 442063

493984
stoichiometry: 1.0
species: 325077
type: SpeciesReference

368643
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

366544
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

523637
stoichiometry: 1.0
species: 339661
type: SpeciesReference

518820
stoichiometry: 1.0
species: 349461
type: SpeciesReference

R786 c
reactant: 421932
type: Reaction
reversible: false
is part of: http://identifiers.org/ec-code/2.1.3.2
name: carbamoyl-phosphate:L-aspartate carbamoyltransferase [cytosol]
is: SBO:0000176
reactant: 421920
product: 421944
fast: false
product: 421956
modifier: 421968
is: R01397

362239
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialinnermembrane
type: Species

433834
stoichiometry: 1.0
species: 350385
type: SpeciesReference

446046
stoichiometry: 1.0
species: 323537
type: SpeciesReference

379671
stoichiometry: 4.0
species: 349161
type: SpeciesReference

575953
stoichiometry: 1.0
species: 324510
type: SpeciesReference

R2682 ec
modifier: 567734
product: 567710
fast: false
type: Reaction
product: 567722
name: Transport [plasma membrane]
reversible: true
reactant: 567698
is: SBO:0000185
reactant: 567686

576085
stoichiometry: 1.0
species: 324546
type: SpeciesReference

404290
stoichiometry: 1.0
species: 326250
type: SpeciesReference

379251
stoichiometry: 1.0
species: 321200
type: SpeciesReference

423840
stoichiometry: 1.0
species: 328276
type: SpeciesReference

R1979 c
modifier: 513784
name: [endoplasmic reticulum membrane]
modifier: 513758
is part of: http://identifiers.org/ec-code/1.14.14.1
reactant: 513706
reversible: true
is: SBO:0000176
modifier: 513771
type: Reaction
product: 513719
modifier: 513745
modifier: 513732
fast: false
is: R07042

555019
stoichiometry: 1.0
species: 322600
type: SpeciesReference

R630 m
is: SBO:0000176
modifier: 410853
fast: false
reversible: false
reactant: 410805
product: 410841
product: 410829
is part of: http://identifiers.org/ec-code/3.6.1.13
is: R01054
reactant: 410817
name: ADP-ribose ribophosphohydrolase [mitochondria]
type: Reaction

R2846 ce
reversible: true
product: 575785
reactant: 575749
reactant: 575761
modifier: 575797
type: Reaction
modifier: 575809
fast: false
product: 575773
is: SBO:0000185
name: Transport [plasma membrane]

R26 lc
product: 374534
reactant: 374523
is: SBO:0000185
fast: false
reversible: false
name: Transport of GMP [lysosomal membrane]
type: Reaction

R404 m
type: Reaction
fast: false
reactant: 393937
product: 393949
product: 393973
product: 393961
name: Succinate:CoA ligase (GDP-forming) [mitochondria]
modifier: 393985
is: SBO:0000176
reactant: 393925
modifier: 393997
reactant: 393913
reversible: true
is part of: http://identifiers.org/ec-code/6.2.1.4
modifier: 394009
is: R00432

468357
stoichiometry: 1.0
species: 341578
type: SpeciesReference

471499
stoichiometry: 1.0
species: 322037
type: SpeciesReference

574237
stoichiometry: 1.0
species: 322159
type: SpeciesReference

529743
stoichiometry: 1.0
species: 353697
type: SpeciesReference

R419 c
type: Reaction
modifier: 395285
is: R00511
modifier: 395273
modifier: 395297
modifier: 395321
reversible: false
name: Cytidine-5'-monophosphate phosphohydrolase [cytosol]
is: SBO:0000176
product: 395261
reactant: 395225
is part of: http://identifiers.org/ec-code/3.1.3.5
product: 395249
reactant: 395237
fast: false
modifier: 395309

354153
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

560574
stoichiometry: 1.0
species: 336439
type: SpeciesReference

329305
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

373551
stoichiometry: 1.0
species: 337543
type: SpeciesReference

401951
stoichiometry: 1.0
species: 321515
type: SpeciesReference

454151
stoichiometry: 1.0
species: 340961
type: SpeciesReference

475206
stoichiometry: 1.0
species: 342716
type: SpeciesReference

479190
stoichiometry: 1.0
species: 321662
type: SpeciesReference

470647
stoichiometry: 1.0
species: 321323
type: SpeciesReference

R1033 c
reactant: 439639
is: SBO:0000176
fast: false
modifier: 439687
product: 439675
type: Reaction
product: 439663
name: Dextrin 6-alpha-D-glucanohydrolase [cytosol]
reactant: 439651
is part of: http://identifiers.org/ec-code/3.2.1.33
reversible: true
is: R02109

558199
stoichiometry: 1.0
species: 345128
type: SpeciesReference

445842
stoichiometry: 1.0
species: 327820
type: SpeciesReference

R1249 r
reactant: 456478
name: 2-Propyn-1-al:NAD+ oxidoreductase [endoplasmic reticulum]
reactant: 456490
modifier: 456538
reactant: 456466
reversible: false
is: SBO:0000176
product: 456526
is part of: http://identifiers.org/ec-code/1.2.1.3
product: 456514
fast: false
type: Reaction
is: R02940
product: 456502

398225
stoichiometry: 1.0
species: 326787
type: SpeciesReference

366880
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

521199
stoichiometry: 1.0
species: 349749
type: SpeciesReference

445194
stoichiometry: 1.0
species: 342909
type: SpeciesReference

363835
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

R2299 c
name: [endoplasmic reticulum membrane]
modifier: 542054
reversible: true
product: 542018
reactant: 542006
modifier: 542066
modifier: 542030
fast: false
modifier: 542042
is: R08339
is part of: http://identifiers.org/ec-code/1.14.14.1
modifier: 542078
type: Reaction
is: SBO:0000176

398876
stoichiometry: 1.0
species: 325077
type: SpeciesReference

394501
stoichiometry: 1.0
species: 323887
type: SpeciesReference

502987
stoichiometry: 1.0
species: 326615
type: SpeciesReference

376695
stoichiometry: 1.0
species: 323260
type: SpeciesReference

496252
stoichiometry: 1.0
species: 321248
type: SpeciesReference

366772
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

363283
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

507078
stoichiometry: 1.0
species: 353841
type: SpeciesReference

524624
stoichiometry: 1.0
species: 330624
type: SpeciesReference

563679
stoichiometry: 1.0
species: 326738
type: SpeciesReference

375014
stoichiometry: 1.0
species: 332912
type: SpeciesReference

350001
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

512658
stoichiometry: 1.0
species: 349017
type: SpeciesReference

528591
stoichiometry: 2.0
species: 322478
type: SpeciesReference

533631
stoichiometry: 1.0
species: 324510
type: SpeciesReference

530451
stoichiometry: 1.0
species: 323002
type: SpeciesReference

518524
stoichiometry: 1.0
species: 323937
type: SpeciesReference

377211
stoichiometry: 1.0
species: 328528
type: SpeciesReference

R1789 c
type: Reaction
is: R05692
reactant: 499243
is: SBO:0000176
modifier: 499303
reactant: 499255
product: 499279
fast: false
product: 499291
is part of: http://identifiers.org/ec-code/1.1.1.271
reversible: false
name: GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing) [cytosol]
reactant: 499267

455974
stoichiometry: 1.0
species: 338995
type: SpeciesReference

545648
stoichiometry: 1.0
species: 322097
type: SpeciesReference

468201
stoichiometry: 1.0
species: 321187
type: SpeciesReference

397805
stoichiometry: 1.0
species: 322503
type: SpeciesReference

323369
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

564831
stoichiometry: 1.0
species: 321274
type: SpeciesReference

453071
stoichiometry: 1.0
species: 344360
type: SpeciesReference

519236
stoichiometry: 1.0
species: 325077
type: SpeciesReference

496148
stoichiometry: 1.0
species: 345512
type: SpeciesReference

427199
stoichiometry: 1.0
species: 326505
type: SpeciesReference

337219
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

362311
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

346639
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

330296
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

462225
stoichiometry: 1.0
species: 335503
type: SpeciesReference

325570
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

R2010 r
reactant: 517384
modifier: 517456
modifier: 517444
modifier: 517432
reactant: 517372
fast: false
product: 517396
modifier: 517420
is part of: http://identifiers.org/ec-code/2.5.1.18
type: Reaction
is: R07070
modifier: 517408
reversible: false
name: 2,3-dihydro-2-S-glutathionyl-3-hydroxy bromobenzene glutathione-lyase (epoxide-forming) [endoplasmic reticulum membrane]
is: SBO:0000176

R243 m
product: 382191
product: 382179
is: SBO:0000176
name: NADH:ferricytochrome-b5 oxidoreductase [mitochondrial outer membrane]
is: R00100
modifier: 382203
reactant: 382143
reactant: 382155
product: 382167
reversible: false
is part of: http://identifiers.org/ec-code/1.6.2.2
type: Reaction
fast: false

415549
stoichiometry: 1.0
species: 326968
type: SpeciesReference

428567
stoichiometry: 1.0
species: 321528
type: SpeciesReference

452627
stoichiometry: 1.0
species: 333476
type: SpeciesReference

extracellular
is: GO:0005615
is: SBO:0000290
constant: true
size: NaN
spatial dimensions: 3.0
name: extracellular space
type: Compartment

445554
stoichiometry: 1.0
species: 321540
type: SpeciesReference

543074
stoichiometry: 1.0
species: 351717
type: SpeciesReference

548612
stoichiometry: 1.0
species: 321795
type: SpeciesReference

482262
stoichiometry: 1.0
species: 321964
type: SpeciesReference

505806
stoichiometry: 1.0
species: 323333
type: SpeciesReference

362695
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

414273
stoichiometry: 1.0
species: 323273
type: SpeciesReference

483113
stoichiometry: 1.0
species: 345020
type: SpeciesReference

509850
stoichiometry: 1.0
species: 321625
type: SpeciesReference

331448
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

530223
stoichiometry: 1.0
species: 346579
type: SpeciesReference

437596
stoichiometry: 1.0
species: 330673
type: SpeciesReference

417756
stoichiometry: 1.0
species: 322892
type: SpeciesReference

349929
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

453383
stoichiometry: 1.0
species: 321722
type: SpeciesReference

554491
stoichiometry: 1.0
species: 327220
type: SpeciesReference

495927
stoichiometry: 1.0
species: 321163
type: SpeciesReference

358364
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

390734
stoichiometry: 1.0
species: 323345
type: SpeciesReference

563262
stoichiometry: 1.0
species: 330865
type: SpeciesReference

357440
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosomalmembrane
type: Species

331375
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

545972
stoichiometry: 1.0
species: 325077
type: SpeciesReference

398536
stoichiometry: 1.0
species: 321323
type: SpeciesReference

497527
stoichiometry: 1.0
species: 346831
type: SpeciesReference

411945
stoichiometry: 1.0
species: 321212
type: SpeciesReference

R2471 ec
reactant: 555187
product: 555223
modifier: 555247
is: SBO:0000185
name: Transport [plasma membrane]
reactant: 555199
reactant: 555175
type: Reaction
product: 555235
fast: false
product: 555211
reversible: false

343235
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

570662
stoichiometry: 2.0
species: 336451
type: SpeciesReference

407986
stoichiometry: 1.0
species: 333536
type: SpeciesReference

353517
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

R2644 ec
modifier: 565790
product: 565778
reactant: 565766
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

520107
stoichiometry: 1.0
species: 323998
type: SpeciesReference

416221
stoichiometry: 1.0
species: 327088
type: SpeciesReference

469304
stoichiometry: 1.0
species: 322503
type: SpeciesReference

428351
stoichiometry: 1.0
species: 332780
type: SpeciesReference

496486
stoichiometry: 1.0
species: 345548
type: SpeciesReference

R1582 c
product: 482537
name: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase [cytosol]
fast: false
product: 482525
type: Reaction
is part of: http://identifiers.org/ec-code/3.1.3.67
reversible: false
is: R04513
reactant: 482501
modifier: 482561
modifier: 482549
reactant: 482513
is: SBO:0000176

375794
stoichiometry: 1.0
species: 340491
type: SpeciesReference

335995
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1660 c
is: SBO:0000176
modifier: 488609
reversible: false
type: Reaction
is: R04780
reactant: 488537
reactant: 488549
name: beta-D-Fructose 1,6-bisphosphate 1-phosphohydrolase [cytosol]
product: 488561
modifier: 488585
modifier: 488597
product: 488573
is part of: http://identifiers.org/ec-code/3.1.3.11
fast: false

R162 ce
product: 377799
reactant: 377787
is: SBO:0000185
fast: false
reversible: false
name: Transport of Dephospho-CoA [plasma membrane]
type: Reaction

427295
stoichiometry: 1.0
species: 332240
type: SpeciesReference

R922 c
is part of: http://identifiers.org/ec-code/2.7.4.6
reactant: 431578
fast: false
product: 431602
reversible: true
product: 431614
modifier: 431626
reactant: 431590
name: ATP:dGDP phosphotransferase [nuclear membrane]
is: R01857
is: SBO:0000176
type: Reaction

539030
stoichiometry: 1.0
species: 348021
type: SpeciesReference

536930
stoichiometry: 1.0
species: 347205
type: SpeciesReference

406306
stoichiometry: 1.0
species: 322232
type: SpeciesReference

567854
stoichiometry: 1.0
species: 336451
type: SpeciesReference

337099
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

454643
stoichiometry: 1.0
species: 326567
type: SpeciesReference

322085
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

R2756 cn
product: 571358
reactant: 571346
is: SBO:0000185
fast: false
reversible: true
name: Transport [nuclear membrane]
type: Reaction

428459
stoichiometry: 1.0
species: 325125
type: SpeciesReference

324932
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

382659
stoichiometry: 1.0
species: 325077
type: SpeciesReference

555307
stoichiometry: 1.0
species: 325619
type: SpeciesReference

326726
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

502663
stoichiometry: 1.0
species: 324131
type: SpeciesReference

478746
stoichiometry: 1.0
species: 325607
type: SpeciesReference

369435
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

R1328 c
name: S-Adenosyl-L-methionine:catechol O-methyltransferase [plasma membrane]
modifier: 462777
product: 462765
is: R03304
product: 462753
reactant: 462729
is part of: http://identifiers.org/ec-code/2.1.1.6
type: Reaction
reversible: true
is: SBO:0000176
fast: false
reactant: 462741

377259
stoichiometry: 1.0
species: 328959
type: SpeciesReference

365275
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgimembrane
type: Species

403511
stoichiometry: 1.0
species: 325294
type: SpeciesReference

328372
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

344588
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

563887
stoichiometry: 1.0
species: 331868
type: SpeciesReference

411837
stoichiometry: 1.0
species: 343914
type: SpeciesReference

324313
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

447978
stoichiometry: 1.0
species: 336631
type: SpeciesReference

R1072 r
is part of: http://identifiers.org/ec-code/5.3.99.5
name: (5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-thromboxane-A2-isomerase [endoplasmic reticulum]
product: 442519
is: SBO:0000176
is: R02268
reversible: false
reactant: 442507
type: Reaction
modifier: 442531
fast: false

342643
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

338738
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

438607
stoichiometry: 1.0
species: 321819
type: SpeciesReference

338047
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

397493
stoichiometry: 1.0
species: 321879
type: SpeciesReference

558043
stoichiometry: 1.0
species: 335228
type: SpeciesReference

398644
stoichiometry: 1.0
species: 321274
type: SpeciesReference

563370
stoichiometry: 1.0
species: 330853
type: SpeciesReference

530379
stoichiometry: 1.0
species: 340961
type: SpeciesReference

453275
stoichiometry: 1.0
species: 333428
type: SpeciesReference

513602
stoichiometry: 1.0
species: 321698
type: SpeciesReference

372975
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondrialinnermembrane
type: Species

347037
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

449322
stoichiometry: 1.0
species: 334100
type: SpeciesReference

441511
stoichiometry: 1.0
species: 322820
type: SpeciesReference

505914
stoichiometry: 1.0
species: 353241
type: SpeciesReference

423156
stoichiometry: 1.0
species: 321515
type: SpeciesReference

339758
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

491872
stoichiometry: 1.0
species: 321163
type: SpeciesReference

426899
stoichiometry: 1.0
species: 334520
type: SpeciesReference

R2044 r
modifier: 521498
is: SBO:0000176
is: R07100
reactant: 521446
name: trichloroethene:glutathione S-(1,2-dichlorovinyl)transferase [endoplasmic reticulum membrane]
fast: false
reactant: 521433
product: 521472
modifier: 521485
reversible: false
modifier: 521537
modifier: 521511
is part of: http://identifiers.org/ec-code/2.5.1.18
product: 521459
type: Reaction
modifier: 521524

452519
stoichiometry: 1.0
species: 333308
type: SpeciesReference

R1784 c
product: 498883
name: L-glutamate:tRNA(Glu) ligase (AMP-forming) [cytosol]
reactant: 498847
is: SBO:0000176
reversible: false
fast: false
is part of: http://identifiers.org/ec-code/6.1.1.17
modifier: 498907
reactant: 498859
type: Reaction
reactant: 498835
product: 498895
is: R05578
product: 498871

568286
stoichiometry: 1.0
species: 336439
type: SpeciesReference

428243
stoichiometry: 1.0
species: 321383
type: SpeciesReference

326615
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

549284
stoichiometry: 1.0
species: 353889
type: SpeciesReference

390050
stoichiometry: 1.0
species: 323076
type: SpeciesReference

384038
stoichiometry: 1.0
species: 321891
type: SpeciesReference

R465 c
product: 398680
reversible: false
product: 398668
fast: false
reactant: 398644
is: SBO:0000176
type: Reaction
reactant: 398656
name: ATP:thiamine diphosphotransferase [cytosol]
is: R00619
is part of: http://identifiers.org/ec-code/2.7.6.2
modifier: 398692

R2270 c
reactant: 538718
name: 4-glutathionyl cyclophosphamide hydrolase [cytosol]
modifier: 538790
product: 538754
modifier: 538838
modifier: 538874
is part of: http://identifiers.org/ec-code/2.5.1.18
reversible: false
modifier: 538802
modifier: 538826
modifier: 538862
modifier: 538766
type: Reaction
is: R08280
modifier: 538850
reactant: 538730
modifier: 538814
product: 538742
modifier: 538778
fast: false
is: SBO:0000176

R2566 ec
modifier: 561270
modifier: 561258
product: 561246
reactant: 561234
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

419916
stoichiometry: 1.0
species: 327640
type: SpeciesReference

434938
stoichiometry: 1.0
species: 330308
type: SpeciesReference

339868
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

493792
stoichiometry: 1.0
species: 335935
type: SpeciesReference

491980
stoichiometry: 1.0
species: 321686
type: SpeciesReference

562842
stoichiometry: 1.0
species: 330925
type: SpeciesReference

377367
stoichiometry: 1.0
species: 330540
type: SpeciesReference

514827
stoichiometry: 1.0
species: 321613
type: SpeciesReference

575317
stoichiometry: 1.0
species: 323585
type: SpeciesReference

554383
stoichiometry: 1.0
species: 325125
type: SpeciesReference

R686 c
reversible: true
name: L-histidine ammonia-lyase (urocanate-forming) [cytosol]
modifier: 414629
product: 414616
type: Reaction
is part of: http://identifiers.org/ec-code/4.3.1.3
is: R01168
reactant: 414590
product: 414603
fast: false
is: SBO:0000176

568130
stoichiometry: 1.0
species: 324546
type: SpeciesReference

343343
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

353625
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: golgi
type: Species

405394
stoichiometry: 1.0
species: 325607
type: SpeciesReference

468800
stoichiometry: 1.0
species: 322503
type: SpeciesReference

324824
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

489832
stoichiometry: 1.0
species: 343647
type: SpeciesReference

322195
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

523241
stoichiometry: 1.0
species: 321540
type: SpeciesReference

R2457 ec
modifier: 554551
modifier: 554539
product: 554527
reactant: 554515
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

R937 c
reactant: 432634
is part of: http://identifiers.org/ec-code/2.1.1.2
product: 432670
is: R01883
reactant: 432646
type: Reaction
product: 432658
is: SBO:0000176
name: S-Adenosyl-L-methionine:guanidinoacetate N-methyltransferase [cytosol]
fast: false
modifier: 432682
reversible: true

R1493 c
reactant: 475854
is: R04018
type: Reaction
product: 475866
reactant: 475842
is part of: http://identifiers.org/ec-code/3.2.1.18
product: 475878
reversible: true
is: SBO:0000176
fast: false
modifier: 475890
name: Acylneuraminyl hydrolase [mitochondrial outer membrane]

462813
stoichiometry: 1.0
species: 325077
type: SpeciesReference

459922
stoichiometry: 1.0
species: 321187
type: SpeciesReference

423300
stoichiometry: 1.0
species: 321187
type: SpeciesReference

518104
stoichiometry: 1.0
species: 321625
type: SpeciesReference

412629
stoichiometry: 1.0
species: 343223
type: SpeciesReference

362047
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

336139
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

432058
stoichiometry: 1.0
species: 330466
type: SpeciesReference

R379 p
is: R00359
product: 392257
reversible: true
name: D-Aspartate:oxygen oxidoreductase (deaminating) [peroxisome]
product: 392245
modifier: 392281
is: SBO:0000176
reactant: 392233
product: 392269
reactant: 392221
is part of: http://identifiers.org/ec-code/1.4.3.1
fast: false
type: Reaction
reactant: 392209

397385
stoichiometry: 1.0
species: 321323
type: SpeciesReference

R346 c
product: 389882
reactant: 389858
product: 389894
fast: false
type: Reaction
modifier: 389906
name: UDP-glucose glucophosphohydrolase [cytosol]
is part of: http://identifiers.org/ec-code/3.6.1.45
reversible: true
is: SBO:0000176
is: R00287
reactant: 389870

467529
stoichiometry: 1.0
species: 325209
type: SpeciesReference

416377
stoichiometry: 1.0
species: 321515
type: SpeciesReference

578820
stoichiometry: 1.0
species: 329794
type: SpeciesReference

426203
stoichiometry: 1.0
species: 322904
type: SpeciesReference

454978
stoichiometry: 1.0
species: 333920
type: SpeciesReference

407878
stoichiometry: 1.0
species: 324788
type: SpeciesReference

570554
stoichiometry: 1.0
species: 325077
type: SpeciesReference

534171
stoichiometry: 1.0
species: 351861
type: SpeciesReference

396857
stoichiometry: 1.0
species: 321163
type: SpeciesReference

435262
stoichiometry: 1.0
species: 321248
type: SpeciesReference

564987
stoichiometry: 1.0
species: 328396
type: SpeciesReference

387890
stoichiometry: 1.0
species: 321212
type: SpeciesReference

445998
stoichiometry: 2.0
species: 332420
type: SpeciesReference

573685
stoichiometry: 1.0
species: 325065
type: SpeciesReference

416485
stoichiometry: 1.0
species: 323489
type: SpeciesReference

412029
stoichiometry: 1.0
species: 339989
type: SpeciesReference

515955
stoichiometry: 1.0
species: 336835
type: SpeciesReference

570902
stoichiometry: 1.0
species: 329732
type: SpeciesReference

388046
stoichiometry: 1.0
species: 321867
type: SpeciesReference

R809 l
product: 423576
product: 423564
type: Reaction
is part of: http://identifiers.org/ec-code/3.5.1.23
is: R01494
is: SBO:0000176
reactant: 423552
fast: false
name: N-Acylsphingosine amidohydrolase [lysosome]
modifier: 423600
reactant: 423540
modifier: 423588
reversible: true

364219
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

353865
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

470947
stoichiometry: 1.0
species: 322539
type: SpeciesReference

430295
stoichiometry: 1.0
species: 340997
type: SpeciesReference

R615 r
is: SBO:0000176
name: GDPmannose:dolichyl-phosphate O-beta-D-mannosyltransferase [endoplasmic reticulum membrane]
product: 409858
reversible: false
type: Reaction
modifier: 409894
reactant: 409846
fast: false
is: R01009
is part of: http://identifiers.org/ec-code/2.4.1.83
product: 409870
reactant: 409834
modifier: 409882

383486
stoichiometry: 1.0
species: 334544
type: SpeciesReference

376587
stoichiometry: 1.0
species: 350733
type: SpeciesReference

482693
stoichiometry: 1.0
species: 344720
type: SpeciesReference

387026
stoichiometry: 1.0
species: 322661
type: SpeciesReference

533043
stoichiometry: 1.0
species: 321236
type: SpeciesReference

423996
stoichiometry: 1.0
species: 328288
type: SpeciesReference

571921
stoichiometry: 1.0
species: 336451
type: SpeciesReference

344024
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

446142
stoichiometry: 1.0
species: 338701
type: SpeciesReference

329757
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: lysosome
type: Species

532527
stoichiometry: 1.0
species: 321964
type: SpeciesReference

543146
stoichiometry: 1.0
species: 351705
type: SpeciesReference

506226
stoichiometry: 1.0
species: 323477
type: SpeciesReference

469724
stoichiometry: 1.0
species: 322503
type: SpeciesReference

R897 c
is part of: http://identifiers.org/ec-code/2.7.7.41
reactant: 429731
is: R01799
name: CTP:phosphatidate cytidyltransferase [endoplasmic reticulum membrane]
fast: false
is: SBO:0000176
product: 429755
reactant: 429743
modifier: 429779
product: 429767
reversible: false
type: Reaction

323211
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

338946
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

362467
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

446682
stoichiometry: 1.0
species: 332096
type: SpeciesReference

553651
stoichiometry: 1.0
species: 330358
type: SpeciesReference

324739
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

353925
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

396713
stoichiometry: 4.0
species: 321686
type: SpeciesReference

512502
stoichiometry: 1.0
species: 349005
type: SpeciesReference

328216
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

533355
stoichiometry: 1.0
species: 340331
type: SpeciesReference

566618
stoichiometry: 1.0
species: 321927
type: SpeciesReference

384962
stoichiometry: 1.0
species: 329118
type: SpeciesReference

501307
stoichiometry: 1.0
species: 322292
type: SpeciesReference

548504
stoichiometry: 1.0
species: 323561
type: SpeciesReference

R2408 c
product: 551011
reactant: 550999
is: R09415
is: SBO:0000176
fast: false
reversible: true
name: [cytosol]
type: Reaction

363175
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

481998
stoichiometry: 1.0
species: 323273
type: SpeciesReference

408058
stoichiometry: 1.0
species: 326701
type: SpeciesReference

575617
stoichiometry: 1.0
species: 336451
type: SpeciesReference

414165
stoichiometry: 1.0
species: 322710
type: SpeciesReference

546308
stoichiometry: 3.0
species: 321212
type: SpeciesReference

442831
stoichiometry: 1.0
species: 333068
type: SpeciesReference

415657
stoichiometry: 1.0
species: 340780
type: SpeciesReference

R2885 ec
modifier: 578124
product: 578112
reactant: 578100
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

329019
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

330065
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

400427
stoichiometry: 1.0
species: 325017
type: SpeciesReference

511758
stoichiometry: 1.0
species: 325089
type: SpeciesReference

392329
stoichiometry: 1.0
species: 322268
type: SpeciesReference

578604
stoichiometry: 1.0
species: 325414
type: SpeciesReference

497419
stoichiometry: 1.0
species: 321163
type: SpeciesReference

353409
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1521 m
name: (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA hydro-liase [mitochondria]
fast: false
is: R04204
modifier: 478074
reversible: false
is: SBO:0000176
is part of: http://identifiers.org/ec-code/4.2.1.17
modifier: 478098
product: 478062
modifier: 478086
reactant: 478038
type: Reaction
modifier: 478110
reactant: 478050

R794 c
reactant: 422472
product: 422496
is: SBO:0000176
type: Reaction
name: (S)-Lactate:oxaloacetate oxidoreductase [cytosol]
fast: false
reactant: 422484
product: 422508
is: R01447
reversible: true

332732
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

475866
stoichiometry: 1.0
species: 321163
type: SpeciesReference

R2829 ec
product: 574885
product: 574873
reactant: 574861
reactant: 574849
is: SBO:0000185
fast: false
reversible: true
name: Transport [plasma membrane]
type: Reaction

457174
stoichiometry: 1.0
species: 335360
type: SpeciesReference

449694
stoichiometry: 1.0
species: 332612
type: SpeciesReference

481026
stoichiometry: 1.0
species: 340853
type: SpeciesReference

538082
stoichiometry: 1.0
species: 321686
type: SpeciesReference

R2679 ec
modifier: 567506
fast: false
reactant: 567458
reversible: true
product: 567494
reactant: 567470
type: Reaction
product: 567482
is: SBO:0000185
name: Transport [plasma membrane]

R1545 c
is part of: http://identifiers.org/ec-code/2.7.8.2
product: 479694
reactant: 479658
fast: false
modifier: 479706
reactant: 479670
is: SBO:0000176
name: CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase [endoplasmic reticulum membrane]
is: R04321
type: Reaction
product: 479682
reversible: true

574393
stoichiometry: 1.0
species: 333716
type: SpeciesReference

572737
stoichiometry: 1.0
species: 325077
type: SpeciesReference

355232
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

447870
stoichiometry: 1.0
species: 322232
type: SpeciesReference

336355
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

459706
stoichiometry: 1.0
species: 321467
type: SpeciesReference

443095
stoichiometry: 1.0
species: 340148
type: SpeciesReference

370791
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

441943
stoichiometry: 1.0
species: 333656
type: SpeciesReference

440899
stoichiometry: 1.0
species: 322880
type: SpeciesReference

450365
stoichiometry: 1.0
species: 321528
type: SpeciesReference

483905
stoichiometry: 1.0
species: 321686
type: SpeciesReference

467421
stoichiometry: 1.0
species: 346316
type: SpeciesReference

539258
stoichiometry: 1.0
species: 321540
type: SpeciesReference

R906 c
is part of: http://identifiers.org/ec-code/1.14.16.4
reversible: true
is: SBO:0000176
name: L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating) [cytosol]
fast: false
modifier: 430403
product: 430379
product: 430367
type: Reaction
reactant: 430319
product: 430355
modifier: 430391
reactant: 430343
reactant: 430331
is: R01814

528015
stoichiometry: 1.0
species: 321163
type: SpeciesReference

545528
stoichiometry: 1.0
species: 328120
type: SpeciesReference

R2697 ec
product: 568670
type: Reaction
name: Transport [plasma membrane]
fast: false
modifier: 568682
reactant: 568634
reversible: true
is: SBO:0000185
reactant: 568646
product: 568658

414382
stoichiometry: 1.0
species: 322588
type: SpeciesReference

493576
stoichiometry: 1.0
species: 321163
type: SpeciesReference

417060
stoichiometry: 1.0
species: 321163
type: SpeciesReference

408682
stoichiometry: 1.0
species: 325888
type: SpeciesReference

370647
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

575533
stoichiometry: 1.0
species: 324510
type: SpeciesReference

446466
stoichiometry: 1.0
species: 332084
type: SpeciesReference

429731
stoichiometry: 1.0
species: 324387
type: SpeciesReference

R1756 p
reactant: 496808
reversible: true
is: R05066
product: 496820
fast: false
type: Reaction
is: SBO:0000176
product: 496844
modifier: 496868
modifier: 496856
reactant: 496796
name: 3-Hydroxy-2-methylpropanoate:NAD+ oxidoreductase [peroxisome]
is part of: http://identifiers.org/ec-code/1.1.1.35
product: 496832

342716
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

R2043 c
modifier: 521420
modifier: 521368
reactant: 521264
is part of: http://identifiers.org/ec-code/2.5.1.18
modifier: 521407
modifier: 521394
reactant: 521251
modifier: 521316
modifier: 521329
modifier: 521342
modifier: 521355
is: R07100
reversible: false
fast: false
modifier: 521303
modifier: 521381
product: 521290
name: trichloroethene:glutathione S-(1,2-dichlorovinyl)transferase [cytosol]
is: SBO:0000176
type: Reaction
product: 521277

R1590 c
modifier: 483137
name: (3R)-3-Hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase [plasma membrane]
is: SBO:0000176
reversible: true
modifier: 483125
product: 483113
product: 483101
is part of: http://identifiers.org/ec-code/2.3.1.85
reactant: 483089
fast: false
is: R04544
type: Reaction

351177
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

401399
stoichiometry: 1.0
species: 325125
type: SpeciesReference

342860
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

560682
stoichiometry: 1.0
species: 325607
type: SpeciesReference

387746
stoichiometry: 1.0
species: 322268
type: SpeciesReference

R16 pc
product: 374294
reactant: 374282
is: SBO:0000185
fast: false
reversible: false
name: Transport of Propanoyl-CoA [peroxisomal membrane]
type: Reaction

433978
stoichiometry: 1.0
species: 323887
type: SpeciesReference

335156
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

399610
stoichiometry: 1.0
species: 325888
type: SpeciesReference

461769
stoichiometry: 1.0
species: 341105
type: SpeciesReference

368787
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulum
type: Species

528639
stoichiometry: 2.0
species: 342293
type: SpeciesReference

506442
stoichiometry: 1.0
species: 333944
type: SpeciesReference

493840
stoichiometry: 1.0
species: 344840
type: SpeciesReference

571609
stoichiometry: 1.0
species: 327328
type: SpeciesReference

407422
stoichiometry: 1.0
species: 321879
type: SpeciesReference

420564
stoichiometry: 1.0
species: 327508
type: SpeciesReference

540806
stoichiometry: 1.0
species: 351525
type: SpeciesReference

R648 m
name: (S)-malate hydro-lyase (fumarate-forming) [mitochondria]
is part of: http://identifiers.org/ec-code/4.2.1.2
reversible: true
product: 411945
fast: false
is: R01082
reactant: 411933
product: 411957
is: SBO:0000176
modifier: 411969
type: Reaction

321795
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: extracellular
type: Species

R2064 c
reactant: 523277
product: 523313
is: R07208
name: 24-Hydroxycholesterol,NADPH:oxygen oxidoreductase(7alpha-hydroxylating) [endoplasmic reticulum membrane]
reactant: 523241
fast: false
product: 523289
is: SBO:0000176
reactant: 523265
reversible: true
modifier: 523325
product: 523301
reactant: 523253
is part of: http://identifiers.org/ec-code/1.14.13.99
type: Reaction

398428
stoichiometry: 1.0
species: 324655
type: SpeciesReference

359744
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

418704
stoichiometry: 1.0
species: 327424
type: SpeciesReference

347253
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R2463 ce
modifier: 554851
product: 554791
fast: false
product: 554803
type: Reaction
product: 554827
reactant: 554767
reactant: 554755
is: SBO:0000185
name: Transport [plasma membrane]
product: 554815
reversible: false
reactant: 554779
modifier: 554839

350841
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: peroxisome
type: Species

511650
stoichiometry: 1.0
species: 321613
type: SpeciesReference

364435
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: endoplasmicreticulummembrane
type: Species

489400
stoichiometry: 1.0
species: 321613
type: SpeciesReference

543597
stoichiometry: 1.0
species: 352029
type: SpeciesReference

392953
stoichiometry: 1.0
species: 329383
type: SpeciesReference

460162
stoichiometry: 1.0
species: 334952
type: SpeciesReference

440671
stoichiometry: 1.0
species: 324059
type: SpeciesReference

R1878 g
reactant: 505627
is: SBO:0000176
is: R06033
product: 505639
modifier: 505687
reactant: 505615
fast: false
has part: http://identifiers.org/ec-code/2.4.1.38
product: 505651
modifier: 505699
reversible: true
type: Reaction
has part: http://identifiers.org/ec-code/2.4.1.90
modifier: 505663
modifier: 505675
name: [Golgi membrane]
modifier: 505711

542522
stoichiometry: 1.0
species: 352005
type: SpeciesReference

365167
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

336055
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

410565
stoichiometry: 1.0
species: 325077
type: SpeciesReference

379479
stoichiometry: 1.0
species: 323125
type: SpeciesReference

415873
stoichiometry: 2.0
species: 325077
type: SpeciesReference

389270
stoichiometry: 1.0
species: 322880
type: SpeciesReference

482537
stoichiometry: 1.0
species: 341503
type: SpeciesReference

467877
stoichiometry: 1.0
species: 336799
type: SpeciesReference

330877
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: nucleus
type: Species

505291
stoichiometry: 1.0
species: 341784
type: SpeciesReference

339419
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

367108
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

R1150 c
reactant: 449082
product: 449094
type: Reaction
product: 449106
is part of: http://identifiers.org/ec-code/4.4.1.5
name: (R)-S-Lactoylglutathione methylglyoxal-lyase (isomerizing) [cytosol]
is: SBO:0000176
fast: false
modifier: 449118
reversible: false
is: R02530

337435
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

575833
stoichiometry: 1.0
species: 324546
type: SpeciesReference

577105
stoichiometry: 1.0
species: 325607
type: SpeciesReference

464421
stoichiometry: 1.0
species: 341261
type: SpeciesReference

R1542 c
name: S-Adenosyl-L-methionine:catechol O-methyltransferase [plasma membrane]
reversible: true
is part of: http://identifiers.org/ec-code/2.1.1.6
fast: false
is: SBO:0000176
modifier: 479526
is: R04301
reactant: 479478
type: Reaction
product: 479514
product: 479502
reactant: 479490

R996 c
fast: false
is part of: http://identifiers.org/ec-code/3.1.1.4
is: R02053
name: Phosphatidylethanolamine 2-acylhydrolase [endoplasmic reticulum membrane]
reactant: 436954
type: Reaction
reactant: 436966
product: 436978
reversible: true
product: 436990
modifier: 437002
is: SBO:0000176

442135
stoichiometry: 1.0
species: 335312
type: SpeciesReference

352557
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

395077
stoichiometry: 1.0
species: 321163
type: SpeciesReference

489292
stoichiometry: 1.0
species: 343441
type: SpeciesReference

544268
stoichiometry: 1.0
species: 352101
type: SpeciesReference

373443
stoichiometry: 1.0
species: 327940
type: SpeciesReference

554167
stoichiometry: 2.0
species: 321163
type: SpeciesReference

R1794 c
modifier: 499687
product: 499675
fast: false
is: SBO:0000176
name: ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase [plasma membrane]
modifier: 499711
reactant: 499639
is: R05795
reactant: 499651
type: Reaction
product: 499663
reversible: true
modifier: 499723
modifier: 499699
is part of: http://identifiers.org/ec-code/2.7.1.154

350229
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 321124
type: Species

492472
stoichiometry: 1.0
species: 321528
type: SpeciesReference

424643
stoichiometry: 1.0
species: 330805
type: SpeciesReference

371727
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: cytosol
type: Species

367503
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: mitochondria
type: Species

365395
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: plasmamembrane
type: Species

R393 m
modifier: 393265
modifier: 393253
name: Succinate:CoA ligase (ADP-forming) [mitochondria]
is part of: http://identifiers.org/ec-code/6.2.1.5
modifier: 393241
product: 393205
is: SBO:0000176
product: 393229
fast: false
type: Reaction
is: R00405
reactant: 393181
reactant: 393169
reversible: true
product: 393217
reactant: 393193

380487
stoichiometry: 1.0
species: 321819
type: SpeciesReference