694864
stoichiometry: 1.0
species: 302701
type: SpeciesReference

709569
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304757
value: 999999.0
type: LocalParameter

714023
stoichiometry: 1.0
species: 302755
type: SpeciesReference

304578
value: 999999.0
type: LocalParameter

714913
stoichiometry: 1.0
species: 302853
type: SpeciesReference

303406
reactant: 706196
reactant: 706220
reversible: true
product: 706256
type: Reaction
product: 706232
notes: Abbreviation: R_GLUDy Synonyms: _0 EC Number: 1.4.1.4 SUBSYSTEM: Glutamate metabolism Equation: [c] : glu-L + h2o + nadp <==> akg + h + nadph + nh4 Confidence Level: 2 genes: LOCUS:BLBBGE_121#ABBREVIATION:gdhA#ECNUMBERS:1.4.1.4# proteins: NAME:Glutamate dehydrogenase#ABBREVIATION:GdhA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_121)
fast: false
reactant: 706208
name: glutamate dehydrogenase (NADP)
product: 706244
product: 706268
kinetic law: 706280

717961
stoichiometry: 1.0
species: 302975
type: SpeciesReference

303725
kinetic law: 717721
product: 717709
product: 717697
reactant: 717685
notes: Abbreviation: R_RBFSb Synonyms: _0 EC Number: 2.5.1.9 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : (2) dmlz --> 4r5au + ribflv Confidence Level: 2 genes: LOCUS:BLBBGE_547#ABBREVIATION:ribE#ECNUMBERS:2.5.1.9# proteins: NAME:riboflavin synthase#ABBREVIATION:RibH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_547)
fast: false
reversible: false
name: riboflavin synthase
type: Reaction

305788
value: 0.0
type: LocalParameter

305013
value: 999999.0
type: LocalParameter

719122
stoichiometry: 1.0
species: 302924
type: SpeciesReference

305360
value: 999999.0
type: LocalParameter

303052
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: O2_O2
type: Species

697628
stoichiometry: 1.0
species: 302985
type: SpeciesReference

713310
stoichiometry: 1.0
species: 302564
type: SpeciesReference

304070
value: 999999.0
type: LocalParameter

304862
value: 0.0
type: LocalParameter

304364
value: 999999.0
type: LocalParameter

304579
value: 0.0
type: LocalParameter

304756
value: 0.0
type: LocalParameter

698341
stoichiometry: 45.7318
species: 302526
type: SpeciesReference

303405
kinetic law: 706184
reversible: false
product: 706135
product: 706147
fast: false
name: L-glutamine transport via ABC system
product: 706172
product: 706160
reactant: 706111
reactant: 706123
notes: Abbreviation: R_GLNabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + gln-L[e] + h2o[c] --> adp[c] + gln-L[c] + h[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
type: Reaction
reactant: 706099

714059
stoichiometry: 1.0
species: 302754
type: SpeciesReference

305789
value: 0.0
type: LocalParameter

303724
notes: Abbreviation: R_RBFSa Synonyms: _0 EC Number: 2.5.1.9 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 4r5au + db4p --> dmlz + (2) h2o + pi Confidence Level: 2 genes: LOCUS:BLBBGE_076#ABBREVIATION:ribC#ECNUMBERS:2.5.1.9# proteins: NAME:_6,7-dimethyl-8-ribityllumazine synthase#ABBREVIATION:RibC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_076)
product: 717649
product: 717661
type: Reaction
name: riboflavin synthase
kinetic law: 717673
product: 717637
reactant: 717613
reversible: false
fast: false
reactant: 717625

305014
value: 0.0
type: LocalParameter

701404
stoichiometry: 1.0
species: 302853
type: SpeciesReference

707075
stoichiometry: 1.0
species: 302415
type: SpeciesReference

719884
stoichiometry: 1.0
species: 302768
type: SpeciesReference

305361
value: 0.0
type: LocalParameter

303051
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Ammonium_H4N
type: Species

698787
stoichiometry: 45.5608
species: 302493
type: SpeciesReference

711987
stoichiometry: 1.0
species: 302904
type: SpeciesReference

304365
value: 0.0
type: LocalParameter

696724
stoichiometry: 1.0
species: 302536
type: SpeciesReference

304861
value: 999999.0
type: LocalParameter

717116
stoichiometry: 1.0
species: 302895
type: SpeciesReference

304755
value: 0.0
type: LocalParameter

305011
value: 0.0
type: LocalParameter

305786
value: 0.0
type: LocalParameter

304860
value: 0.0
type: LocalParameter

304362
value: 0.0
type: LocalParameter

304576
value: 0.0
type: LocalParameter

303510
reactant: 709788
product: 709800
product: 709812
name: malate dehydrogenase
reactant: 709776
notes: Abbreviation: R_MDH Synonyms: _0 EC Number: 1.1.1.37 SUBSYSTEM: Citric Acid Cycle Equation: [c] : mal-L + nad <==> h + nadh + oaa Confidence Level: 2 genes: LOCUS:BLBBGE_617#ABBREVIATION:mdh#ECNUMBERS:1.1.1.37# proteins: NAME:malate dehydrogenase#ABBREVIATION:Mdh# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_617)
product: 709825
reversible: true
kinetic law: 709837
fast: false
type: Reaction

707761
stoichiometry: 1.0
species: 302672
type: SpeciesReference

303511
kinetic law: 709911
reactant: 709849
fast: false
notes: Abbreviation: R_ME2 Synonyms: _6 EC Number: 1.1.1.40 SUBSYSTEM: Anaplerotic reactions Equation: [c] : mal-L + nadp --> co2 + nadph + pyr Confidence Level: 2 genes: LOCUS:BLBBGE_412#ABBREVIATION:maeB# proteins: NAME:Malic enzyme (NADP)#ABBREVIATION:Mae# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_412)
product: 709899
product: 709886
name: malic enzyme (NADP)
reactant: 709862
reversible: false
type: Reaction
product: 709874

304754
value: 0.0
type: LocalParameter

716657
stoichiometry: 1.0
species: 302853
type: SpeciesReference

305012
value: 0.0
type: LocalParameter

303722
kinetic law: 717601
reversible: false
name: riboflavin kinase
product: 717589
notes: Abbreviation: R_RBFK Synonyms: _0 EC Number: 2.7.1.26 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + ribflv --> adp + fmn + h Confidence Level: 2 genes: LOCUS:BLBBGE_072#ABBREVIATION:ribF#ECNUMBERS:2.7.1.26,-!-,2.7.7.2# proteins: NAME:Flavokinase and FAD synthetase#ABBREVIATION:RibF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_072)
fast: false
type: Reaction
reactant: 717539
product: 717576
product: 717564
reactant: 717552

708323
stoichiometry: 1.0
species: 302679
type: SpeciesReference

305787
value: 999999.0
type: LocalParameter

701380
stoichiometry: 1.0
species: 302760
type: SpeciesReference

304363
value: -999999.0
type: LocalParameter

304577
value: -999999.0
type: LocalParameter

710742
stoichiometry: 1.0
species: 302719
type: SpeciesReference

705239
stoichiometry: 1.0
species: 302659
type: SpeciesReference

720150
stoichiometry: 1.0
species: 302511
type: SpeciesReference

705919
stoichiometry: 1.0
species: 302719
type: SpeciesReference

303402
fast: false
kinetic law: 706087
type: Reaction
name: guanylate kinase (GMP:ATP)
reversible: true
notes: Abbreviation: R_GK1 Synonyms: _0 EC Number: 2.7.4.8 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + gmp <==> adp + gdp Confidence Level: 2 genes: LOCUS:BLBBGE_298#ABBREVIATION:gmk#ECNUMBERS:2.7.4.8# proteins: NAME:Guanylate kinase#ABBREVIATION:Gmk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_298)
product: 706063
reactant: 706039
product: 706075
reactant: 706051

712728
stoichiometry: 1.0
species: 302562
type: SpeciesReference

699572
stoichiometry: 7.0
species: 302536
type: SpeciesReference

304429
value: 0.0
type: LocalParameter

303729
type: Reaction
reactant: 717889
notes: Abbreviation: R_RNDR3 Synonyms: _0 EC Number: 1.17.4.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : cdp + trdrd --> dcdp + h2o + trdox Confidence Level: 2 genes: LOCUS:BLBBGE_310#ABBREVIATION:nrdA#ECNUMBERS:1.17.4.1# LOCUS:BLBBGE_p006#ABBREVIATION:nrdF#ECNUMBERS:1.17.4.1# proteins: NAME:ribonucleoside-diphosphate reductase subunit alpha#ABBREVIATION:NrdA# NAME:ribonucleotide-diphosphate reductase beta subunit#ABBREVIATION:NrdF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_310 and BLBBGE_p006)
name: ribonucleoside-diphosphate reductase (CDP)
reactant: 717877
product: 717901
fast: false
reversible: false
kinetic law: 717937
product: 717925
product: 717913

304368
value: -999999.0
type: LocalParameter

305259
value: -999999.0
type: LocalParameter

304074
value: 999999.0
type: LocalParameter

705871
stoichiometry: 1.0
species: 302934
type: SpeciesReference

305364
value: 0.0
type: LocalParameter

699283
stoichiometry: 20.0
species: 302659
type: SpeciesReference

304130
value: 0.0
type: LocalParameter

304619
value: 0.0
type: LocalParameter

305010
value: 0.0
type: LocalParameter

716934
stoichiometry: 1.0
species: 302490
type: SpeciesReference

707208
stoichiometry: 1.0
species: 302656
type: SpeciesReference

303401
reactant: 705979
product: 706015
reactant: 705991
kinetic law: 706027
reversible: false
name: glutamine-fructose-6-phosphate transaminase
product: 706003
notes: Abbreviation: R_GF6PTA Synonyms: _0 EC Number: 2.6.1.16 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : f6p + gln-L --> gam6p + glu-L Confidence Level: 2 genes: LOCUS:BLBBGE_289#ABBREVIATION:glmS#ECNUMBERS:2.6.1.16# proteins: NAME:Glucosamine fructose-6-phosphate aminotransferase (isomerizing)#ABBREVIATION:GlmS# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_289)
type: Reaction
fast: false

695080
stoichiometry: 1.0
species: 302536
type: SpeciesReference

719242
stoichiometry: 1.0
species: 302538
type: SpeciesReference

706063
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304073
value: 0.0
type: LocalParameter

722082
stoichiometry: 1.0
species: 302989
type: SpeciesReference

303353
kinetic law: 704667
product: 704654
reactant: 704641
notes: Abbreviation: R_EX_succ_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : succ <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Succinate exchange
type: Reaction

704865
stoichiometry: 1.0
species: 302994
type: SpeciesReference

714781
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304131
value: 0.0
type: LocalParameter

703375
stoichiometry: 1.0
species: 303010
type: SpeciesReference

697592
stoichiometry: 1.0
species: 302516
type: SpeciesReference

718613
stoichiometry: 1.0
species: 302939
type: SpeciesReference

303727
reversible: false
fast: false
product: 717841
type: Reaction
name: ribonucleoside-diphosphate reductase (GDP)
reactant: 717805
reactant: 717817
product: 717829
product: 717853
notes: Abbreviation: R_RNDR2 Synonyms: _0 EC Number: 1.17.4.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : gdp + trdrd --> dgdp + h2o + trdox Confidence Level: 2 genes: LOCUS:BLBBGE_310#ABBREVIATION:nrdA#ECNUMBERS:1.17.4.1# LOCUS:BLBBGE_p006#ABBREVIATION:nrdF#ECNUMBERS:1.17.4.1# proteins: NAME:ribonucleoside-diphosphate reductase subunit alpha#ABBREVIATION:NrdA# NAME:ribonucleotide-diphosphate reductase beta subunit#ABBREVIATION:NrdF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_310 and BLBBGE_p006)
kinetic law: 717865

302770
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: O-Phospho-4-hydroxy-L-threonine_C4H8NO7P
type: Species

304618
value: 0.0
type: LocalParameter

304759
value: 0.0
type: LocalParameter

303514
reactant: 709935
product: 709971
product: 709996
kinetic law: 710008
fast: false
notes: Abbreviation: R_METabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + met-L[e] --> adp[c] + h[c] + met-L[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 709959
type: Reaction
name: L-methionine transport via ABC system
product: 709983
reactant: 709923
reactant: 709947
reversible: false

717685
stoichiometry: 2.0
species: 302577
type: SpeciesReference

304427
value: 0.0
type: LocalParameter

305362
value: 0.0
type: LocalParameter

303350
kinetic law: 704628
product: 704615
reactant: 704602
notes: Abbreviation: R_EX_so4_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : so4 <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Sulfate exchange
type: Reaction

304366
value: 0.0
type: LocalParameter

304072
value: 0.0
type: LocalParameter

305257
value: 0.0
type: LocalParameter

303050
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Nicotinate_C6H4NO2
type: Species

713286
stoichiometry: 1.0
species: 302565
type: SpeciesReference

714673
stoichiometry: 1.0
species: 302526
type: SpeciesReference

703946
stoichiometry: 1.0
species: 302667
type: SpeciesReference

703147
stoichiometry: 1.0
species: 302655
type: SpeciesReference

696095
stoichiometry: 1.0
species: 302554
type: SpeciesReference

708686
stoichiometry: 1.0
species: 302655
type: SpeciesReference

705093
stoichiometry: 1.0
species: 302493
type: SpeciesReference

303726
reactant: 717745
reactant: 717733
product: 717781
product: 717757
notes: Abbreviation: R_RNDR1 Synonyms: _0 EC Number: 1.17.4.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : adp + trdrd --> dadp + h2o + trdox Confidence Level: 2 genes: LOCUS:BLBBGE_310#ABBREVIATION:nrdA#ECNUMBERS:1.17.4.1# LOCUS:BLBBGE_p006#ABBREVIATION:nrdF#ECNUMBERS:1.17.4.1# proteins: NAME:ribonucleoside-diphosphate reductase subunit alpha#ABBREVIATION:NrdA# NAME:ribonucleotide-diphosphate reductase beta subunit#ABBREVIATION:NrdF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_310 and BLBBGE_p006)
type: Reaction
product: 717769
kinetic law: 717793
reversible: false
fast: false
name: ribonucleoside-diphosphate reductase (ADP)

720282
stoichiometry: 1.0
species: 302567
type: SpeciesReference

304758
value: 0.0
type: LocalParameter

712548
stoichiometry: 1.0
species: 302492
type: SpeciesReference

303839
value: 0.0
type: LocalParameter

304428
value: 999999.0
type: LocalParameter

304617
value: 999999.0
type: LocalParameter

303515
name: methionine adenosyltransferase
product: 710056
notes: Abbreviation: R_METAT Synonyms: _0 EC Number: 2.5.1.6 SUBSYSTEM: Methionine Metabolism Equation: [c] : atp + h2o + met-L --> amet + pi + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_345#ABBREVIATION:metK#ECNUMBERS:2.5.1.6# proteins: NAME:methionine adenosyltransferase I#ABBREVIATION:MetK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_345)
kinetic law: 710092
product: 710068
reversible: false
fast: false
reactant: 710020
type: Reaction
reactant: 710044
product: 710080
reactant: 710032

710416
stoichiometry: 1.0
species: 302719
type: SpeciesReference

696832
stoichiometry: 2.0
species: 302503
type: SpeciesReference

304071
value: 0.0
type: LocalParameter

304971
value: -999999.0
type: LocalParameter

705021
stoichiometry: 1.0
species: 302597
type: SpeciesReference

721659
stoichiometry: 1.0
species: 302978
type: SpeciesReference

710340
stoichiometry: 1.0
species: 302724
type: SpeciesReference

698631
stoichiometry: 0.0276
species: 302763
type: SpeciesReference

304134
value: 0.0
type: LocalParameter

304290
value: 0.0
type: LocalParameter

304211
value: 0.0
type: LocalParameter

718166
stoichiometry: 1.0
species: 302853
type: SpeciesReference

702229
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305255
value: 999999.0
type: LocalParameter

303243
reactant: 702120
product: 702156
name: diaminohydroxyphosphoribosylaminopryrimidine deaminase (25drapp)
type: Reaction
product: 702168
reactant: 702132
notes: Abbreviation: R_DHPPDA2 Synonyms: _0 EC Number: 3.5.4.26 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 25drapp + h + h2o --> 5apru + nh4 Confidence Level: 2 Riboflavin-specific deaminaseAR genes: LOCUS:BLBBGE_143#ABBREVIATION:ribD#ECNUMBERS:3.5.4.26,-!-,1.1.1.193# proteins: NAME:pyrimidine deaminase and pyrimidine reductase#ABBREVIATION:RibD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_143)
kinetic law: 702180
reactant: 702144
reversible: false
fast: false

303114
kinetic law: 696336
fast: false
reactant: 696288
type: Reaction
notes: Abbreviation: R_AGMT Synonyms: _0 EC Number: 3.5.3.11 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : agm + h2o --> ptrc + urea Confidence Level: 2 genes: LOCUS:BLBBGE_059#ABBREVIATION:speB#ECNUMBERS:3.5.3.11# proteins: NAME:agmatinase#ABBREVIATION:SpeB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_059)
product: 696324
name: agmatinase
reversible: false
product: 696312
reactant: 696300

700595
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304425
value: 0.0
type: LocalParameter

709788
stoichiometry: 1.0
species: 302719
type: SpeciesReference

707316
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303838
value: 999999.0
type: LocalParameter

698281
stoichiometry: 0.488
species: 302504
type: SpeciesReference

695675
stoichiometry: 1.0
species: 302450
type: SpeciesReference

303958
value: 0.0
type: LocalParameter

714565
stoichiometry: 1.0
species: 302622
type: SpeciesReference

705505
stoichiometry: 1.0
species: 302617
type: SpeciesReference

704756
stoichiometry: 1.0
species: 302953
type: SpeciesReference

304135
value: 0.0
type: LocalParameter

305369
value: 0.0
type: LocalParameter

305256
value: 0.0
type: LocalParameter

304973
value: 999999.0
type: LocalParameter

713781
stoichiometry: 1.0
species: 302745
type: SpeciesReference

304212
value: 0.0
type: LocalParameter

719944
stoichiometry: 1.0
species: 303000
type: SpeciesReference

303244
product: 702217
reversible: false
fast: false
reactant: 702205
type: Reaction
name: dihydropteroate synthase
notes: Abbreviation: R_DHPS2 Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 4abz + 6hmhptpp --> dhpt + h + ppi Confidence Level: 2 JLR- similar to DHPS except uses 6hmhptpp (has ketone rather than OH) genes: LOCUS:BLBBGE_102#ABBREVIATION:folP#ECNUMBERS:2.5.1.15# proteins: NAME:Dihydropteroate synthase#ABBREVIATION:FolP# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_102)
reactant: 702192
kinetic law: 702253
product: 702229
product: 702241

700259
stoichiometry: 1.0
species: 302526
type: SpeciesReference

715333
stoichiometry: 1.0
species: 302760
type: SpeciesReference

304426
value: 0.0
type: LocalParameter

304869
value: 999999.0
type: LocalParameter

719351
stoichiometry: 1.0
species: 302493
type: SpeciesReference

303622
name: Octaprenyl pyrophosphate synthase
reversible: false
fast: false
type: Reaction
product: 713539
reactant: 713527
notes: Abbreviation: R_OCTDPS Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : frdp + (5) ipdp --> octdp + (5) ppi Confidence Level: 2 JLR- EC 2.5.1.- genes: LOCUS:BLBBGE_303#ABBREVIATION:ispB#ECNUMBERS:2.5.1.-# proteins: NAME:Octaprenyl-diphosphate synthase#ABBREVIATION:IspB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_303)
reactant: 713515
kinetic law: 713563
product: 713551

706172
stoichiometry: 1.0
species: 302853
type: SpeciesReference

697396
stoichiometry: 1.0
species: 302463
type: SpeciesReference

702868
stoichiometry: 1.0
species: 302425
type: SpeciesReference

303837
value: 0.0
type: LocalParameter

697250
stoichiometry: 1.0
species: 302869
type: SpeciesReference

708068
stoichiometry: 1.0
species: 302875
type: SpeciesReference

708104
stoichiometry: 1.0
species: 302633
type: SpeciesReference

718954
stoichiometry: 1.0
species: 302511
type: SpeciesReference

305167
value: 999999.0
type: LocalParameter

703485
stoichiometry: 1.0
species: 303015
type: SpeciesReference

305019
value: 0.0
type: LocalParameter

713177
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304132
value: 999999.0
type: LocalParameter

304292
value: 999999.0
type: LocalParameter

304423
value: 0.0
type: LocalParameter

303112
kinetic law: 696180
product: 696168
product: 696156
reactant: 696144
notes: Abbreviation: R_ADSL2r Synonyms: _0 EC Number: 4.3.2.2 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : 25aics --> aicar + fum Confidence Level: 2 JLR- added reversible form of ADSL2 genes: LOCUS:BLBBGE_487#ABBREVIATION:purB#ECNUMBERS:4.3.2.2# proteins: NAME:Adenylosuccinate lyase#ABBREVIATION:PurB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_487)
fast: false
reversible: false
name: adenylosuccinate lyase
type: Reaction

305253
value: 0.0
type: LocalParameter

305366
value: 999999.0
type: LocalParameter

705179
stoichiometry: 1.0
species: 302659
type: SpeciesReference

695735
stoichiometry: 1.0
species: 302628
type: SpeciesReference

304974
value: 0.0
type: LocalParameter

303623
fast: false
reactant: 713575
notes: Abbreviation: R_OHPBAT Synonyms: _0 EC Number: 2.6.1.52 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : glu-L + ohpb <==> akg + phthr Confidence Level: 2 NCD genes: LOCUS:BLBBGE_428#ABBREVIATION:serC#ECNUMBERS:2.6.1.52# LOCUS:BLBBGE_144#ABBREVIATION:serC#ECNUMBERS:2.6.1.52# proteins: NAME:Phosphoserine aminotransferase#ABBREVIATION:SerC# NAME:Phosphoserine aminotransferase#ABBREVIATION:SerC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_428) or (BLBBGE_144)
type: Reaction
reversible: true
name: O-Phospho-4-hydroxy-L-threonine:2-oxoglutarate aminotransferase
kinetic law: 713623
product: 713611
reactant: 713587
product: 713599

304868
value: -999999.0
type: LocalParameter

716862
stoichiometry: 1.0
species: 302490
type: SpeciesReference

699307
stoichiometry: 14.0
species: 302724
type: SpeciesReference

707425
stoichiometry: 2.0
species: 302719
type: SpeciesReference

716225
stoichiometry: 1.0
species: 302610
type: SpeciesReference

303956
value: 999999.0
type: LocalParameter

303836
value: 0.0
type: LocalParameter

304133
value: 0.0
type: LocalParameter

705445
stoichiometry: 1.0
species: 302655
type: SpeciesReference

699175
stoichiometry: 5.0
species: 302697
type: SpeciesReference

304291
value: 0.0
type: LocalParameter

303113
product: 696264
product: 696252
notes: Abbreviation: R_ADSS Synonyms: _0 EC Number: 6.3.4.4 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : asp-L + gtp + imp --> dcamp + gdp + (2) h + pi Confidence Level: 2 genes: LOCUS:BLBBGE_488#ABBREVIATION:purA#ECNUMBERS:6.3.4.4# proteins: NAME:Adenylosuccinate synthetase#ABBREVIATION:PurA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_488)
name: adenylosuccinate synthase
reactant: 696204
kinetic law: 696276
type: Reaction
reversible: false
reactant: 696216
product: 696240
reactant: 696192
product: 696228
fast: false

304210
value: 999999.0
type: LocalParameter

305254
value: 0.0
type: LocalParameter

303242
kinetic law: 702108
product: 702096
reactant: 702084
notes: Abbreviation: R_dhorSt Synonyms: _0 Equation: dhor-S[e] <==> dhor-S[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: S-Dihydroorotate transporter
type: Reaction

305367
value: 0.0
type: LocalParameter

304975
value: 0.0
type: LocalParameter

701636
stoichiometry: 1.0
species: 302933
type: SpeciesReference

304424
value: 999999.0
type: LocalParameter

702156
stoichiometry: 1.0
species: 302464
type: SpeciesReference

304867
value: 0.0
type: LocalParameter

303957
value: 0.0
type: LocalParameter

708795
stoichiometry: 1.0
species: 302436
type: SpeciesReference

303835
value: 0.0
type: LocalParameter

718721
stoichiometry: 1.0
species: 302910
type: SpeciesReference

719014
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302900
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Ribulose 5-phosphate_C5H9O8P
type: Species

302983
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Uroporphyrinogen III_C40H36N4O16
type: Species

304421
value: 0.0
type: LocalParameter

711879
stoichiometry: 1.0
species: 302719
type: SpeciesReference

303056
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Phosphate_HO4P
type: Species

710634
stoichiometry: 1.0
species: 302720
type: SpeciesReference

304753
value: 999999.0
type: LocalParameter

697102
stoichiometry: 1.0
species: 302888
type: SpeciesReference

305251
value: 0.0
type: LocalParameter

304360
value: 999999.0
type: LocalParameter

303954
value: 0.0
type: LocalParameter

305679
value: 999999.0
type: LocalParameter

303834
value: 999999.0
type: LocalParameter

305017
value: 999999.0
type: LocalParameter

304138
value: 0.0
type: LocalParameter

709412
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304866
value: 0.0
type: LocalParameter

303118
name: adenosylhomocysteinase
reactant: 696444
product: 696456
reversible: true
kinetic law: 696480
reactant: 696432
fast: false
notes: Abbreviation: R_AHC Synonyms: _0 EC Number: 3.3.1.1 SUBSYSTEM: Methionine Metabolism Equation: [c] : ahcys + h2o <==> adn + hcys-L Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
type: Reaction
product: 696468

304976
value: -999999.0
type: LocalParameter

712474
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303055
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Phenylalanine_C9H11NO2
type: Species

304361
value: 0.0
type: LocalParameter

304752
value: 0.0
type: LocalParameter

696589
stoichiometry: 1.0
species: 302465
type: SpeciesReference

304422
value: 0.0
type: LocalParameter

695891
stoichiometry: 1.0
species: 302511
type: SpeciesReference

305018
value: 0.0
type: LocalParameter

711711
stoichiometry: 1.0
species: 302493
type: SpeciesReference

720572
stoichiometry: 1.0
species: 302684
type: SpeciesReference

707184
stoichiometry: 1.0
species: 302995
type: SpeciesReference

303955
value: -999999.0
type: LocalParameter

303833
value: 0.0
type: LocalParameter

304139
value: 0.0
type: LocalParameter

304865
value: 999999.0
type: LocalParameter

718094
stoichiometry: 1.0
species: 302526
type: SpeciesReference

303119
type: Reaction
notes: Abbreviation: R_AICART Synonyms: _0 EC Number: 2.1.2.3 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : 10fthf + aicar --> fprica + thf Confidence Level: 2 genes: LOCUS:BLBBGE_480#ABBREVIATION:purH#ECNUMBERS:3.5.4.10,-!-,2.1.2.3# proteins: NAME:AICAR transformylase and IMP cyclohydrolase#ABBREVIATION:PurH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_480)
product: 696517
reactant: 696505
fast: false
kinetic law: 696541
name: phosphoribosylaminoimidazolecarboxamide formyltransferase
reactant: 696492
reversible: false
product: 696529

304977
value: 999999.0
type: LocalParameter

304751
value: 0.0
type: LocalParameter

711590
stoichiometry: 1.0
species: 302493
type: SpeciesReference

695008
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305677
value: 0.0
type: LocalParameter

304136
value: 999999.0
type: LocalParameter

711445
stoichiometry: 1.0
species: 302526
type: SpeciesReference

711650
stoichiometry: 1.0
species: 302493
type: SpeciesReference

303832
value: 0.0
type: LocalParameter

716104
stoichiometry: 1.0
species: 302873
type: SpeciesReference

719086
stoichiometry: 1.0
species: 302924
type: SpeciesReference

305015
value: 0.0
type: LocalParameter

303952
value: 999999.0
type: LocalParameter

709376
stoichiometry: 1.0
species: 302689
type: SpeciesReference

305168
value: 0.0
type: LocalParameter

698497
stoichiometry: 45.5608
species: 302655
type: SpeciesReference

304864
value: 0.0
type: LocalParameter

304978
value: 0.0
type: LocalParameter

303057
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: (R)-Pantothenate_C9H16NO5
type: Species

304420
value: 999999.0
type: LocalParameter

705991
stoichiometry: 1.0
species: 302628
type: SpeciesReference

304863
value: 0.0
type: LocalParameter

304750
value: 0.0
type: LocalParameter

698401
stoichiometry: 0.0135
species: 302557
type: SpeciesReference

302903
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Sedoheptulose 7-phosphate_C7H13O10P
type: Species

704138
stoichiometry: 1.0
species: 303045
type: SpeciesReference

304137
value: 0.0
type: LocalParameter

706967
stoichiometry: 1.0
species: 302865
type: SpeciesReference

305250
value: 999999.0
type: LocalParameter

303831
value: 0.0
type: LocalParameter

305016
value: 0.0
type: LocalParameter

305169
value: 0.0
type: LocalParameter

696240
stoichiometry: 1.0
species: 302626
type: SpeciesReference

305678
value: 0.0
type: LocalParameter

722009
stoichiometry: 1.0
species: 302526
type: SpeciesReference

303953
value: 0.0
type: LocalParameter

701975
stoichiometry: 1.0
species: 302570
type: SpeciesReference

304979
value: 0.0
type: LocalParameter

303117
kinetic law: 696420
product: 696408
product: 696396
notes: Abbreviation: R_AGPR Synonyms: _0 EC Number: 1.2.1.38 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : acg5sa + nadp + pi <==> acg5p + h + nadph Confidence Level: 2 genes: LOCUS:BLBBGE_314#ABBREVIATION:argC#ECNUMBERS:1.2.1.38# proteins: NAME:N-acetylglutamate phosphate reductase#ABBREVIATION:ArgC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_314)
type: Reaction
reactant: 696372
fast: false
reactant: 696360
reversible: true
reactant: 696348
name: N-acetyl-g-glutamyl-phosphate reductase
product: 696384

709351
stoichiometry: 1.0
species: 302691
type: SpeciesReference

302980
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: UMP_C9H11N2O9P
type: Species

721052
stoichiometry: 1.0
species: 302853
type: SpeciesReference

302608
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Formate_CH1O2
type: Species

304208
value: 0.0
type: LocalParameter

302679
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Isoleucine_C6H13NO2
type: Species

305736
value: 999999.0
type: LocalParameter

715490
stoichiometry: 1.0
species: 302865
type: SpeciesReference

303951
value: 0.0
type: LocalParameter

715551
stoichiometry: 1.0
species: 302536
type: SpeciesReference

305688
value: 0.0
type: LocalParameter

721731
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302452
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _4-Hydroxy-L-threonine_C4H9NO4
type: Species

719726
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304297
value: 0.0
type: LocalParameter

699391
stoichiometry: 1.0
species: 302489
type: SpeciesReference

304430
value: 0.0
type: LocalParameter

699657
stoichiometry: 1.0
species: 302733
type: SpeciesReference

707641
stoichiometry: 1.0
species: 302511
type: SpeciesReference

304207
value: 0.0
type: LocalParameter

303239
reactant: 702036
product: 702048
reversible: false
name: dihydroorotic acid (menaquinone-8)
type: Reaction
reactant: 702024
kinetic law: 702072
notes: Abbreviation: R_DHORD5 Synonyms: _0 EC Number: 1.3.3.1 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : dhor-S + mqn8 --> mql8 + orot Confidence Level: 2 JLR genes: LOCUS:BLBBGE_513#ABBREVIATION:pyrD#ECNUMBERS:1.3.3.1# proteins: NAME:Dihydroorotate dehydrogenase#ABBREVIATION:PyrD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_513)
fast: false
product: 702060

709935
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303830
value: 999999.0
type: LocalParameter

305737
value: 0.0
type: LocalParameter

303950
value: 0.0
type: LocalParameter

721428
stoichiometry: 1.0
species: 302659
type: SpeciesReference

704641
stoichiometry: 1.0
species: 302925
type: SpeciesReference

721803
stoichiometry: 1.0
species: 302980
type: SpeciesReference

302451
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _4-amino-4-deoxychorismate_C10H10NO5
type: Species

305586
value: 0.0
type: LocalParameter

304298
value: 0.0
type: LocalParameter

305473
value: 0.0
type: LocalParameter

700933
stoichiometry: 1.0
species: 302550
type: SpeciesReference

303238
kinetic law: 702011
product: 701999
product: 701987
reactant: 701975
notes: Abbreviation: R_DHNPA2 Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : dhnpt <==> 6hmhpt + gcald Confidence Level: 2 JLR- similar to DHNPA except the 'pterin product is different genes: LOCUS:BLBBGE_292#ABBREVIATION:folB#ECNUMBERS:4.1.2.25# proteins: NAME:dihydroneopterin aldolase#ABBREVIATION:FolB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_292)
fast: false
reversible: true
name: dihydroneopterin aldolase
type: Reaction

302606
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: FMN_C17H19N4O9P
type: Species

304206
value: 999999.0
type: LocalParameter

305734
value: 0.0
type: LocalParameter

304129
value: 0.0
type: LocalParameter

712801
stoichiometry: 1.0
species: 302648
type: SpeciesReference

715827
stoichiometry: 1.0
species: 302869
type: SpeciesReference

302454
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _4-Methyl-2-oxopentanoate_C6H9O3
type: Species

305686
value: 0.0
type: LocalParameter

700475
stoichiometry: 1.0
species: 302893
type: SpeciesReference

302984
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Uracil_C4H4N2O2
type: Species

696625
stoichiometry: 1.0
species: 302853
type: SpeciesReference

717564
stoichiometry: 1.0
species: 302493
type: SpeciesReference

715624
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304205
value: -999999.0
type: LocalParameter

302678
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: IDP_C10H11N4O11P2
type: Species

305735
value: 0.0
type: LocalParameter

697471
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304128
value: 999999.0
type: LocalParameter

302605
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide_C8H13N2O9P
type: Species

705397
stoichiometry: 1.0
species: 302705
type: SpeciesReference

305471
value: 0.0
type: LocalParameter

305685
value: 999999.0
type: LocalParameter

702530
stoichiometry: 1.0
species: 302865
type: SpeciesReference

716717
stoichiometry: 1.0
species: 302534
type: SpeciesReference

305584
value: 0.0
type: LocalParameter

701853
stoichiometry: 1.0
species: 302567
type: SpeciesReference

722215
stoichiometry: 1.0
species: 302993
type: SpeciesReference

302985
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Urea_CH4N2O
type: Species

707859
stoichiometry: 1.0
species: 302929
type: SpeciesReference

720354
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302675
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Isochorismate_C10H8O6
type: Species

304204
value: 0.0
type: LocalParameter

303626
notes: Abbreviation: R_OMBZLM Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 2ombzl + amet --> 2ommbl + ahcys + h Confidence Level: 2 JLR genes: LOCUS:BLBBGE_110#ABBREVIATION:ubiE#ECNUMBERS:2.1.1.-# proteins: NAME:_2-DMK methyltransferase and 2-octaprenyl-6-methoxy-1,4-benzoquinonol methylase#ABBREVIATION:UbiE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_110)
reactant: 713648
product: 713660
name: _2-Octaprenyl-6-methoxy-benzoquinol methylase
type: Reaction
product: 713684
product: 713672
reversible: false
reactant: 713635
kinetic law: 713696
fast: false

718589
stoichiometry: 1.0
species: 302432
type: SpeciesReference

713539
stoichiometry: 1.0
species: 302739
type: SpeciesReference

302562
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dGMP_C10H12N5O7P
type: Species

305470
value: 0.0
type: LocalParameter

304293
value: 0.0
type: LocalParameter

718371
stoichiometry: 1.0
species: 302468
type: SpeciesReference

694936
stoichiometry: 1.0
species: 302493
type: SpeciesReference

302676
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Isocitrate_C6H5O7
type: Species

717236
stoichiometry: 1.0
species: 302995
type: SpeciesReference

709207
stoichiometry: 1.0
species: 302441
type: SpeciesReference

703848
stoichiometry: 1.0
species: 303031
type: SpeciesReference

695239
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303235
type: Reaction
reactant: 701890
product: 701915
product: 701927
product: 701939
fast: false
reactant: 701902
kinetic law: 701963
product: 701951
reversible: false
notes: Abbreviation: R_DHNAOT Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : dhna + octdp --> 2dmmq8 + co2 + h + ppi Confidence Level: 2 EC 2.5.1-;Reaction is uncharged the loss of 2H (conversion from quinol to quinone form is thought to be spontaneous) genes: LOCUS:BLBBGE_268#ABBREVIATION:menA#ECNUMBERS:2.5.1.-# proteins: NAME:_1,4 dihydroxy-2-napthoate octaprenyltransferase#ABBREVIATION:MenA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_268)
name: _1,4-dihydroxy-2-naphthoate octaprenyltransferase

709291
stoichiometry: 1.0
species: 302596
type: SpeciesReference

304203
value: 0.0
type: LocalParameter

710863
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304294
value: 0.0
type: LocalParameter

305683
value: -999999.0
type: LocalParameter

697176
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305738
value: 0.0
type: LocalParameter

702446
stoichiometry: 1.0
species: 302570
type: SpeciesReference

711237
stoichiometry: 1.0
species: 302714
type: SpeciesReference

302988
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Urea_CH4N2O
type: Species

696408
stoichiometry: 1.0
species: 302724
type: SpeciesReference

700511
stoichiometry: 0.5
species: 302733
type: SpeciesReference

303121
kinetic law: 696675
product: 696662
reactant: 696650
notes: Abbreviation: R_AIRC3 Synonyms: _2 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : 5caiz --> 5aizc Confidence Level: 2 JLR- E.coli uses a two enzymes in the phosphoribosylaminoimidazole carboxylase step to generate 5aizc genes: LOCUS:BLBBGE_485#ABBREVIATION:purE#ECNUMBERS:4.1.1.21# proteins: NAME:phosphoribosylaminoimidazole carboxylase II#ABBREVIATION:PurE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_485)
fast: false
reversible: false
name: phosphoribosylaminoimidazole carboxylase (mutase rxn)
type: Reaction

304202
value: 999999.0
type: LocalParameter

305589
value: 0.0
type: LocalParameter

712279
stoichiometry: 1.0
species: 302556
type: SpeciesReference

304295
value: -999999.0
type: LocalParameter

303234
notes: Abbreviation: R_DHFS Synonyms: _0 EC Number: 6.3.2.12 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + dhpt + glu-L --> adp + dhf + pi Confidence Level: 2 genes: LOCUS:BLBBGE_182#ABBREVIATION:folC#ECNUMBERS:6.3.2.12,-!-,6.3.2.17# proteins: NAME:folypolyglutamate synthase and dihydrofolate synthase#ABBREVIATION:FolC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_182)
fast: false
product: 701841
reactant: 701805
type: Reaction
product: 701866
name: dihydrofolate synthase
reactant: 701817
reversible: false
reactant: 701829
kinetic law: 701878
product: 701853

302560
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Dodecanoyl-ACP (n-C12:0ACP)_C23H43N2O8PRS
type: Species

302450
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _4-Aminobenzoate_C7H6NO2
type: Species

704417
stoichiometry: 1.0
species: 302859
type: SpeciesReference

305739
value: -999999.0
type: LocalParameter

303627
reactant: 713708
reactant: 713720
name: _2-Oxo-4-methyl-3-carboxypentanoate decarboxylation
kinetic law: 713756
reversible: false
notes: Abbreviation: R_OMCDC Synonyms: _0 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 3c4mop + h --> 4mop + co2 Confidence Level: 2 Continuation of EC 1.1.1.85 reaction genes: LOCUS:BLBBGE_070#ABBREVIATION:leuB#ECNUMBERS:1.1.1.85# proteins: NAME:Isopropylmalate dehydrogenase#ABBREVIATION:LeuB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_070)
fast: false
type: Reaction
product: 713732
product: 713744

302609
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Formate_CH1O2
type: Species

302989
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Uridine_C9H12N2O6
type: Species

303120
reversible: false
reactant: 696553
fast: false
product: 696613
product: 696601
reactant: 696577
notes: Abbreviation: R_AIRC2 Synonyms: _0 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : air + atp + hco3 --> 5caiz + adp + h + pi Confidence Level: 1 JLR- reaction according to Neidhardt pg 563 and 569. According to Meyer et al. Biochemistry 38: 3012-3018pp, this pathway is used in prokaryotes and uses hco3 instead of co2 genes: none proteins: none citations: none GENE ASSOCIATION:
kinetic law: 696637
product: 696625
product: 696589
reactant: 696565
type: Reaction
name: phosphoribosylaminoimidazole carboxylase

304201
value: 0.0
type: LocalParameter

304296
value: 999999.0
type: LocalParameter

303233
name: dihydrofolate reductase
type: Reaction
kinetic law: 701793
reactant: 701757
reactant: 701744
product: 701781
product: 701769
fast: false
notes: Abbreviation: R_DHFR Synonyms: _0 EC Number: 1.5.1.3 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : dhf + h + nadph <==> nadp + thf Confidence Level: 2 The enzyme from animals and some micro-organisms also slowly reduces folate to 5,6,7,8-tetrahydrofolate genes: LOCUS:BLBBGE_449#ABBREVIATION:folA#ECNUMBERS:1.5.1.3# proteins: NAME:dihydrofolate reductase#ABBREVIATION:FolA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_449)
reversible: true
reactant: 701732

305588
value: 999999.0
type: LocalParameter

305681
value: 0.0
type: LocalParameter

704357
stoichiometry: 1.0
species: 303055
type: SpeciesReference

697322
stoichiometry: 1.0
species: 302659
type: SpeciesReference

710287
stoichiometry: 1.0
species: 302708
type: SpeciesReference

302561
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dGDP_C10H12N5O10P2
type: Species

302674
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Hypoxanthine_C5H4N4O
type: Species

302671
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Hydroxymethylbilane_C40H38N4O17
type: Species

304077
value: 0.0
type: LocalParameter

305793
value: 999999.0
type: LocalParameter

703521
stoichiometry: 1.0
species: 303018
type: SpeciesReference

305680
value: 0.0
type: LocalParameter

303345
kinetic law: 704516
product: 704504
reactant: 704492
notes: Abbreviation: R_EX_pro_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : pro-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Proline exchange
type: Reaction

303598
reactant: 712716
fast: false
product: 712740
notes: Abbreviation: R_NTPP1 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dgtp + h2o --> dgmp + h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
type: Reaction
reactant: 712704
kinetic law: 712765
name: Nucleoside triphosphate pyrophosphorylase (dgtp)
product: 712728
reversible: false
product: 712753

304615
value: 0.0
type: LocalParameter

713648
stoichiometry: 1.0
species: 302509
type: SpeciesReference

302600
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2
type: Species

302566
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Dihydroxyacetone phosphate_C3H5O6P
type: Species

716597
stoichiometry: 1.0
species: 302500
type: SpeciesReference

699415
stoichiometry: 6.0
species: 302697
type: SpeciesReference

304078
value: 999999.0
type: LocalParameter

302672
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Homoserine_C4H9NO3
type: Species

709074
stoichiometry: 1.0
species: 302479
type: SpeciesReference

304582
value: 0.0
type: LocalParameter

304616
value: -999999.0
type: LocalParameter

703739
stoichiometry: 1.0
species: 303026
type: SpeciesReference

303599
reactant: 712789
product: 712801
product: 712825
name: Nucleoside triphosphate pyrophosphorylase (gtp)
reversible: false
reactant: 712777
fast: false
product: 712813
type: Reaction
notes: Abbreviation: R_NTPP2 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : gtp + h2o --> gmp + h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
kinetic law: 712837

718262
stoichiometry: 1.0
species: 302500
type: SpeciesReference

302459
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-((R)-4-Phosphopantothenoyl)-L-cysteine_C12H20N2O9PS
type: Species

302567
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _7,8-Dihydrofolate_C19H19N7O6
type: Species

710972
stoichiometry: 1.0
species: 302723
type: SpeciesReference

305791
value: -999999.0
type: LocalParameter

302564
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Deoxyguanosine_C10H13N5O4
type: Species

304075
value: 0.0
type: LocalParameter

701162
stoichiometry: 1.0
species: 302552
type: SpeciesReference

696517
stoichiometry: 1.0
species: 302612
type: SpeciesReference

700873
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304613
value: 999999.0
type: LocalParameter

716381
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304359
value: 0.0
type: LocalParameter

303519
fast: false
kinetic law: 710225
product: 710213
reversible: false
product: 710189
product: 710201
type: Reaction
reactant: 710165
name: _mevalonate kinase
notes: Abbreviation: R_MEVK1x Synonyms: _0 EC Number: 2.7.1.36 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c]: atp + mev-R --> 5pmev + adp + (2) h Confidence Level: 2 genes: LOCUS:BLBBGE_085#ABBREVIATION:mvaK#ECNUMBERS:2.7.1.36# proteins: NAME:_mevalonate kinase#ABBREVIATION:MvaK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_085)
reactant: 710177

698982
stoichiometry: 1.0
species: 302560
type: SpeciesReference

721209
stoichiometry: 1.0
species: 302975
type: SpeciesReference

302670
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Histidinol_C6H12N3O
type: Species

704200
stoichiometry: 1.0
species: 302714
type: SpeciesReference

696468
stoichiometry: 1.0
species: 302663
type: SpeciesReference

717817
stoichiometry: 1.0
species: 302949
type: SpeciesReference

719665
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304580
value: 0.0
type: LocalParameter

304076
value: 0.0
type: LocalParameter

713854
stoichiometry: 1.0
species: 302745
type: SpeciesReference

303342
kinetic law: 704480
product: 704468
reactant: 704456
notes: Abbreviation: R_EX_ppbng_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : ppbng <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Porphobilinogen exchange
type: Reaction

305479
value: 0.0
type: LocalParameter

720787
stoichiometry: 1.0
species: 302954
type: SpeciesReference

712169
stoichiometry: 1.0
species: 302683
type: SpeciesReference

303518
reversible: true
kinetic law: 710152
notes: Abbreviation: R_METS Synonyms: _0 EC Number: 2.1.1.14 SUBSYSTEM: Methionine Metabolism Equation: [c] : 5mthf + hcys-L <==> met-L + thf Confidence Level: 2 genes: LOCUS:BLBBGE_114#ABBREVIATION:metE#ECNUMBERS:2.1.1.14# proteins: NAME:Cobalamin independent methionine synthase#ABBREVIATION:MetE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_114)
reactant: 710116
reactant: 710104
product: 710140
type: Reaction
name: methionine synthase
product: 710128
fast: false

709629
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304614
value: 0.0
type: LocalParameter

304358
value: 0.0
type: LocalParameter

700667
stoichiometry: 1.0
species: 302651
type: SpeciesReference

302565
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dGTP_C10H12N5O13P3
type: Species

717347
stoichiometry: 1.0
species: 302526
type: SpeciesReference

698027
stoichiometry: 1.0
species: 302522
type: SpeciesReference

305478
value: 0.0
type: LocalParameter

304587
value: 0.0
type: LocalParameter

720635
stoichiometry: 1.0
species: 302442
type: SpeciesReference

305583
value: 0.0
type: LocalParameter

305797
value: 0.0
type: LocalParameter

305732
value: 999999.0
type: LocalParameter

712753
stoichiometry: 1.0
species: 302865
type: SpeciesReference

721536
stoichiometry: 1.0
species: 302853
type: SpeciesReference

700031
stoichiometry: 1.0
species: 302538
type: SpeciesReference

303720
notes: Abbreviation: R_PYDXPP Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : h2o + pydx5p --> pi + pydx Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 717419
reactant: 717431
kinetic law: 717467
product: 717443
type: Reaction
fast: false
name: Pyridoxal 5-phosphate phosphatase
reversible: false
product: 717455

302456
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _4-Phospho-D-erythronate_C4H6O8P
type: Species

302604
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Fe2+_Fe
type: Species

303409
reactant: 706292
product: 706341
reversible: false
kinetic law: 706365
reactant: 706304
reactant: 706316
type: Reaction
notes: Abbreviation: R_GLUPRT Synonyms: _0 EC Number: 2.4.2.14 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : gln-L + h2o + prpp --> glu-L + ppi + pram Confidence Level: 2 genes: LOCUS:BLBBGE_483#ABBREVIATION:purF#ECNUMBERS:2.4.2.14# proteins: NAME:Amidophosphoribosyltransferase#ABBREVIATION:PurF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_483)
fast: false
product: 706328
name: glutamine phosphoribosyldiphosphate amidotransferase
product: 706353

715141
stoichiometry: 1.0
species: 302859
type: SpeciesReference

304611
value: 0.0
type: LocalParameter

709825
stoichiometry: 1.0
species: 302738
type: SpeciesReference

719460
stoichiometry: 3.0
species: 302724
type: SpeciesReference

303349
kinetic law: 704589
product: 704577
reactant: 704565
notes: Abbreviation: R_EX_ser_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : ser-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Serine exchange
type: Reaction

304586
value: 0.0
type: LocalParameter

305582
value: 999999.0
type: LocalParameter

710068
stoichiometry: 1.0
species: 302853
type: SpeciesReference

714457
stoichiometry: 1.0
species: 302853
type: SpeciesReference

302455
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _4-Phospho-L-aspartate_C4H6NO7P
type: Species

303721
type: Reaction
kinetic law: 717527
notes: Abbreviation: R_PYRt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h[e] + pyr[e] <==> h[c] + pyr[c] Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
product: 717515
reactant: 717491
reactant: 717479
fast: false
product: 717503
reversible: true
name: pyruvate reversible transport via proton symport

702373
stoichiometry: 1.0
species: 302687
type: SpeciesReference

305733
value: 0.0
type: LocalParameter

304699
value: 0.0
type: LocalParameter

304612
value: 0.0
type: LocalParameter

706545
stoichiometry: 1.0
species: 302536
type: SpeciesReference

304698
value: 0.0
type: LocalParameter

711165
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304585
value: 0.0
type: LocalParameter

305476
value: 0.0
type: LocalParameter

304079
value: 0.0
type: LocalParameter

708928
stoichiometry: 1.0
species: 302659
type: SpeciesReference

706485
stoichiometry: 1.0
species: 302638
type: SpeciesReference

305730
value: 0.0
type: LocalParameter

721877
stoichiometry: 1.0
species: 302983
type: SpeciesReference

305581
value: 0.0
type: LocalParameter

305795
value: 0.0
type: LocalParameter

721269
stoichiometry: 1.0
species: 302493
type: SpeciesReference

712958
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302458
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-4'-Phosphopantothenate_C9H15NO8P
type: Species

302602
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Fe2+_Fe
type: Species

706618
stoichiometry: 1.0
species: 302660
type: SpeciesReference

708468
stoichiometry: 1.0
species: 302655
type: SpeciesReference

700367
stoichiometry: 1.0
species: 302658
type: SpeciesReference

722106
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305475
value: 999999.0
type: LocalParameter

304584
value: 999999.0
type: LocalParameter

304610
value: 0.0
type: LocalParameter

720700
stoichiometry: 1.0
species: 302953
type: SpeciesReference

304697
value: 999999.0
type: LocalParameter

698703
stoichiometry: 2.23E-4
species: 302934
type: SpeciesReference

713068
stoichiometry: 1.0
species: 302526
type: SpeciesReference

305731
value: -999999.0
type: LocalParameter

705655
stoichiometry: 1.0
species: 302709
type: SpeciesReference

305580
value: 0.0
type: LocalParameter

302601
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Fructose 1,6-bisphosphate_C6H10O12P2
type: Species

717745
stoichiometry: 1.0
species: 302949
type: SpeciesReference

302569
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _1,4-Dihydroxy-2-naphthoate_C11H7O4
type: Species

717455
stoichiometry: 1.0
species: 302890
type: SpeciesReference

304209
value: 0.0
type: LocalParameter

303346
kinetic law: 704552
product: 704540
reactant: 704528
notes: Abbreviation: R_EX_pyr_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : pyr <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Pyruvate exchange
type: Reaction

701744
stoichiometry: 1.0
species: 302659
type: SpeciesReference

696144
stoichiometry: 1.0
species: 302413
type: SpeciesReference

303108
fast: false
name: adenylyl-sulfate kinase
notes: Abbreviation: R_ADSK Synonyms: _0 EC Number: 2.7.1.25 SUBSYSTEM: Cysteine Metabolism Equation: [c] : aps + atp --> adp + h + paps Confidence Level: 2 genes: LOCUS:BLBBGE_275#ABBREVIATION:cysC#ECNUMBERS:2.7.1.25# proteins: NAME:adenosine 5'-phosphosulfate kinase#ABBREVIATION:CysC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_275)
product: 696047
reversible: false
product: 696071
product: 696059
kinetic law: 696083
type: Reaction
reactant: 696035
reactant: 696023

695470
stoichiometry: 1.0
species: 302660
type: SpeciesReference

304743
value: 0.0
type: LocalParameter

716189
stoichiometry: 1.0
species: 302628
type: SpeciesReference

304408
value: 0.0
type: LocalParameter

304350
value: 0.0
type: LocalParameter

304564
value: 0.0
type: LocalParameter

713080
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303042
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Lysine_C6H15N2O2
type: Species

305798
value: 0.0
type: LocalParameter

703303
stoichiometry: 1.0
species: 303008
type: SpeciesReference

713213
stoichiometry: 1.0
species: 302655
type: SpeciesReference

716645
stoichiometry: 1.0
species: 302884
type: SpeciesReference

305000
value: 0.0
type: LocalParameter

303734
reversible: false
name: succinyl-diaminopimelate desuccinylase
reactant: 718214
notes: Abbreviation: R_SDPDS Synonyms: _0 EC Number: 3.5.1.18 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : h2o + sl26da --> 26dap-LL + succ Confidence Level: 2 genes: LOCUS:BLBBGE_320#ABBREVIATION:dapE#ECNUMBERS:3.5.1.18# proteins: NAME:Succinyl-diaminopimelate desuccinylase#ABBREVIATION:DapE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_320)
fast: false
product: 718238
reactant: 718202
type: Reaction
product: 718226
kinetic law: 718250

305799
value: 999999.0
type: LocalParameter

708335
stoichiometry: 1.0
species: 302853
type: SpeciesReference

303109
kinetic law: 696132
product: 696120
product: 696107
reactant: 696095
notes: Abbreviation: R_ADSL1r Synonyms: _0 EC Number: 4.3.2.2 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : dcamp --> amp + fum Confidence Level: 2 JLR- added reversible form of ADSL1 genes: LOCUS:BLBBGE_487#ABBREVIATION:purB#ECNUMBERS:4.3.2.2# proteins: NAME:Adenylosuccinate lyase#ABBREVIATION:PurB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_487)
fast: false
reversible: false
name: adenylsuccinate lyase
type: Reaction

707773
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304407
value: 0.0
type: LocalParameter

718022
stoichiometry: 1.0
species: 302900
type: SpeciesReference

304742
value: 0.0
type: LocalParameter

696688
stoichiometry: 1.0
species: 302500
type: SpeciesReference

304565
value: -999999.0
type: LocalParameter

303041
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Leucine_C6H13NO2
type: Species

705227
stoichiometry: 1.0
species: 302469
type: SpeciesReference

302763
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Peptidoglycan subunit of Blattabacterium Blattella germanica_C40H62N8O21
type: Species

303737
name: _2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
product: 718359
notes: Abbreviation: R_SEPHCHC Synonyms: _1 EC Number: 4.1.1.71 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : ichor + akg + (2) h --> co2 + 5ephchc Confidence Level: 2 JLR genes: LOCUS:BLBBGE_056#ABBREVIATION:menD#ECNUMBERS:4.1.1.71,-!-,2.2.1.9# proteins: NAME:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase#ABBREVIATION:MenD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_056)
product: 718371
reactant: 718335
fast: false
reactant: 718347
type: Reaction
reversible: false
kinetic law: 718383
reactant: 718323

719134
stoichiometry: 1.0
species: 302600
type: SpeciesReference

305001
value: 0.0
type: LocalParameter

304745
value: 999999.0
type: LocalParameter

714035
stoichiometry: 1.0
species: 302949
type: SpeciesReference

722179
stoichiometry: 1.0
species: 302493
type: SpeciesReference

695807
stoichiometry: 2.0
species: 302493
type: SpeciesReference

714901
stoichiometry: 3.0
species: 302713
type: SpeciesReference

302764
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Phenylalanine_C9H11NO2
type: Species

303591
name: _5'-nucleotidase (AMP)
product: 712548
product: 712560
notes: Abbreviation: R_NTD7 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : amp + h2o --> adn + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
reversible: false
fast: false
kinetic law: 712572
reactant: 712536
type: Reaction
reactant: 712524

304566
value: 999999.0
type: LocalParameter

713322
stoichiometry: 1.0
species: 302865
type: SpeciesReference

304850
value: -999999.0
type: LocalParameter

304352
value: 999999.0
type: LocalParameter

303040
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: potassium_K
type: Species

303736
product: 718298
product: 718286
notes: Abbreviation: R_SDPTA Synonyms: _0 EC Number: 2.6.1.17 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : akg + sl26da <==> glu-L + sl2a6o Confidence Level: 2 genes: LOCUS:BLBBGE_315#ABBREVIATION:dapC#ECNUMBERS:2.6.1.11,-!-,2.6.1.17# LOCUS:BLBBGE_623#ABBREVIATION:dapC#ECNUMBERS:2.6.1.11,-!-,2.6.1.17# proteins: NAME:bifunctional acetylornithine transaminase/N-succinyldiaminopimelate aminotransferase#ABBREVIATION:DapC# NAME:N-succinyldiaminopimelate aminotransferase#ABBREVIATION:DapC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_315) or (BLBBGE_623)
type: Reaction
name: succinyldiaminopimelate transaminase
reactant: 718274
reactant: 718262
reversible: true
fast: false
kinetic law: 718311

707087
stoichiometry: 1.0
species: 302608
type: SpeciesReference

305002
value: 0.0
type: LocalParameter

695951
stoichiometry: 1.0
species: 302492
type: SpeciesReference

304567
value: 0.0
type: LocalParameter

304409
value: 0.0
type: LocalParameter

304744
value: 0.0
type: LocalParameter

714107
stoichiometry: 1.0
species: 302641
type: SpeciesReference

709001
stoichiometry: 1.0
species: 302659
type: SpeciesReference

714047
stoichiometry: 2.0
species: 302659
type: SpeciesReference

302765
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Phenylalanine_C9H11NO2
type: Species

711999
stoichiometry: 1.0
species: 302538
type: SpeciesReference

303361
kinetic law: 704816
product: 704804
reactant: 704792
notes: Abbreviation: R_EX_tyr_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : tyr-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Tyrosine exchange
type: Reaction

304353
value: 0.0
type: LocalParameter

719872
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303590
name: _5'-nucleotidase (dAMP)
reactant: 712461
reversible: false
fast: false
product: 712499
reactant: 712474
type: Reaction
kinetic law: 712511
product: 712486
notes: Abbreviation: R_NTD6 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : damp + h2o --> dad-2 + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:

696736
stoichiometry: 1.0
species: 302720
type: SpeciesReference

698775
stoichiometry: 0.402
species: 302993
type: SpeciesReference

303502
reactant: 709509
reactant: 709497
product: 709521
notes: Abbreviation: R_LEUTA Synonyms: _2 EC Number: 2.6.1.42 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 4mop + glu-L <==> akg + leu-L Confidence Level: 2 genes: LOCUS:BLBBGE_455#ABBREVIATION:ilvE#ECNUMBERS:2.6.1.42,-!-,2.6.1.2# LOCUS:BLBBGE_342#ABBREVIATION:tyrB#ECNUMBERS:2.6.1.57# proteins: NAME:Branched-chain-amino-acid aminotransferase#ABBREVIATION:IlvE# NAME:Tyrosine aminotransferase#ABBREVIATION:TyrB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_342) or (BLBBGE_455)
reversible: true
type: Reaction
fast: false
kinetic law: 709545
name: leucine transaminase
product: 709533

303739
reactant: 718456
fast: false
reversible: false
product: 718480
kinetic law: 718505
name: L-serine via sodium symport
product: 718493
notes: Abbreviation: R_SERt4 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: na1[e] + ser-L[e] --> na1[c] + ser-L[c] Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 718468
type: Reaction

304404
value: 0.0
type: LocalParameter

304747
value: 0.0
type: LocalParameter

701514
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303948
value: 999999.0
type: LocalParameter

304415
value: 0.0
type: LocalParameter

304568
value: 0.0
type: LocalParameter

721161
stoichiometry: 1.0
species: 302964
type: SpeciesReference

707003
stoichiometry: 1.0
species: 302655
type: SpeciesReference

717697
stoichiometry: 1.0
species: 302460
type: SpeciesReference

717503
stoichiometry: 1.0
species: 302659
type: SpeciesReference

718601
stoichiometry: 1.0
species: 302893
type: SpeciesReference

713298
stoichiometry: 1.0
species: 302655
type: SpeciesReference

699487
stoichiometry: 13.0
species: 302723
type: SpeciesReference

305350
value: 0.0
type: LocalParameter

712680
stoichiometry: 1.0
species: 302853
type: SpeciesReference

714661
stoichiometry: 1.0
species: 302446
type: SpeciesReference

703135
stoichiometry: 1.0
species: 302431
type: SpeciesReference

711915
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304354
value: 0.0
type: LocalParameter

304060
value: 999999.0
type: LocalParameter

305245
value: 0.0
type: LocalParameter

304140
value: 999999.0
type: LocalParameter

303362
kinetic law: 704853
product: 704840
reactant: 704828
notes: Abbreviation: R_EX_urea_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : urea <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Urea exchange
type: Reaction

303503
notes: Abbreviation: R_LYSabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + lys-L[e] --> adp[c] + h[c] + lys-L[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 709581
type: Reaction
kinetic law: 709641
reversible: false
product: 709605
name: L-lysine transport via ABC system
product: 709629
reactant: 709557
reactant: 709569
fast: false
product: 709593
product: 709617

712536
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304629
value: 999999.0
type: LocalParameter

304416
value: 0.0
type: LocalParameter

694851
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304746
value: 0.0
type: LocalParameter

303949
value: 0.0
type: LocalParameter

304569
value: -999999.0
type: LocalParameter

708674
stoichiometry: 1.0
species: 302426
type: SpeciesReference

715948
stoichiometry: 1.0
species: 302655
type: SpeciesReference

720294
stoichiometry: 1.0
species: 302584
type: SpeciesReference

303738
product: 718432
reactant: 718408
product: 718420
name: serine O-acetyltransferase
type: Reaction
reversible: true
fast: false
notes: Abbreviation: R_SERAT Synonyms: _4 EC Number: 2.3.1.30 SUBSYSTEM: Cysteine Metabolism Equation: [c] : accoa + ser-L <==> acser + coa Confidence Level: 2 genes: LOCUS:BLBBGE_276#ABBREVIATION:cysE#ECNUMBERS:2.3.1.30# proteins: NAME:Serine acetyltransferase#ABBREVIATION:CysE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_276)
reactant: 718395
kinetic law: 718444

304141
value: 0.0
type: LocalParameter

706751
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305351
value: 0.0
type: LocalParameter

696844
stoichiometry: 1.0
species: 302526
type: SpeciesReference

714997
stoichiometry: 1.0
species: 302472
type: SpeciesReference

706811
stoichiometry: 1.0
species: 302526
type: SpeciesReference

305246
value: 0.0
type: LocalParameter

304355
value: -999999.0
type: LocalParameter

304406
value: 999999.0
type: LocalParameter

700139
stoichiometry: 1.0
species: 302526
type: SpeciesReference

302760
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Phosphoenolpyruvate_C3H2O6P
type: Species

699584
stoichiometry: 8.0
species: 302655
type: SpeciesReference

304749
value: 999999.0
type: LocalParameter

720162
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304142
value: 0.0
type: LocalParameter

303595
reactant: 712644
notes: Abbreviation: R_NTD9 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : gmp + h2o --> gsn + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
reversible: false
kinetic law: 712692
reactant: 712656
name: _5'-nucleotidase (GMP)
type: Reaction
product: 712680
product: 712668
fast: false

699271
stoichiometry: 1.0
species: 302489
type: SpeciesReference

304062
value: 0.0
type: LocalParameter

304356
value: 999999.0
type: LocalParameter

720932
stoichiometry: 1.0
species: 302853
type: SpeciesReference

305352
value: 999999.0
type: LocalParameter

304748
value: 0.0
type: LocalParameter

719230
stoichiometry: 1.0
species: 302526
type: SpeciesReference

706051
stoichiometry: 1.0
species: 302648
type: SpeciesReference

304418
value: -999999.0
type: LocalParameter

707545
stoichiometry: 1.0
species: 302655
type: SpeciesReference

704877
stoichiometry: 1.0
species: 303077
type: SpeciesReference

304143
value: 0.0
type: LocalParameter

304357
value: 0.0
type: LocalParameter

305248
value: 0.0
type: LocalParameter

304061
value: 0.0
type: LocalParameter

303594
kinetic law: 712632
name: _5'-nucleotidase (dGMP)
reactant: 712596
type: Reaction
product: 712620
product: 712608
reactant: 712584
notes: Abbreviation: R_NTD8 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dgmp + h2o --> dgsn + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
reversible: false
fast: false

303365
kinetic law: 704889
product: 704877
reactant: 704865
notes: Abbreviation: R_EX_val_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : val-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Valine exchange
type: Reaction

722094
stoichiometry: 1.0
species: 302626
type: SpeciesReference

305353
value: 0.0
type: LocalParameter

710538
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304411
value: 0.0
type: LocalParameter

305241
value: 0.0
type: LocalParameter

305354
value: 0.0
type: LocalParameter

304400
value: 999999.0
type: LocalParameter

304962
value: -999999.0
type: LocalParameter

302910
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Shikimate_C7H9O5
type: Species

303195
reversible: false
name: cystathionine b-lyase
kinetic law: 700487
product: 700463
product: 700451
reactant: 700427
notes: Abbreviation: R_CYSTL Synonyms: _0 EC Number: 4.4.1.8 SUBSYSTEM: Methionine Metabolism Equation: [c] : cyst-L + h2o --> hcys-L + nh4 + pyr Confidence Level: 2 genes: LOCUS:BLBBGE_568#ABBREVIATION:metBC#ECNUMBERS:4.4.1.8# proteins: NAME:Cystathionine gamma-synthase-cystathionine beta-lyase#ABBREVIATION:MetC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_568)
fast: false
product: 700475
reactant: 700439
type: Reaction

303253
reactant: 702494
product: 702506
notes: Abbreviation: R_DNTPPA Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : ahdt + h2o --> dhpmp + h + ppi Confidence Level: 2 JLR- Neidhardt pg 667 genes: LOCUS:BLBBGE_190#ABBREVIATION:idi#ECNUMBERS:5.3.3.2# proteins: NAME:isopentenyl diphosphate isomerase#ABBREVIATION:Idi# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_190)
fast: false
product: 702518
name: Dihydroneopterin triphosphate pyrophosphatase
reactant: 702482
kinetic law: 702542
product: 702530
type: Reaction
reversible: false

305007
value: 0.0
type: LocalParameter

713189
stoichiometry: 1.0
species: 302865
type: SpeciesReference

304144
value: 999999.0
type: LocalParameter

304280
value: 0.0
type: LocalParameter

703026
stoichiometry: 1.0
species: 302592
type: SpeciesReference

707112
stoichiometry: 1.0
species: 302865
type: SpeciesReference

707437
stoichiometry: 3.0
species: 302659
type: SpeciesReference

303944
value: 0.0
type: LocalParameter

716237
stoichiometry: 1.0
species: 302633
type: SpeciesReference

303848
value: 999999.0
type: LocalParameter

695723
stoichiometry: 1.0
species: 302531
type: SpeciesReference

303611
type: Reaction
name: Nucleoside triphosphate pyrophosphorylase (utp)
product: 713262
kinetic law: 713274
product: 713249
reactant: 713213
notes: Abbreviation: R_NTPP8 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : h2o + utp --> h + ppi + ump Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
reversible: false
fast: false
reactant: 713225
product: 713237

716874
stoichiometry: 1.0
species: 302895
type: SpeciesReference

305568
value: 0.0
type: LocalParameter

305242
value: 0.0
type: LocalParameter

304412
value: 0.0
type: LocalParameter

305355
value: 0.0
type: LocalParameter

705457
stoichiometry: 1.0
species: 302698
type: SpeciesReference

303194
kinetic law: 700415
name: cysteine synthase
product: 700391
reactant: 700355
reactant: 700367
fast: false
product: 700403
product: 700379
reversible: false
type: Reaction
notes: Abbreviation: R_CYSS Synonyms: _8 SUBSYSTEM: Cysteine Metabolism Equation: [c] : acser + h2s --> ac + cys-L + h Confidence Level: 2 EC changed to 2.5.1.47 from 4.2.99.8 genes: LOCUS:BLBBGE_277#ABBREVIATION:cysK#ECNUMBERS:2.5.1.47# proteins: NAME:Cysteine synthase A#ABBREVIATION:CysK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_277)

699163
stoichiometry: 16.0
species: 302659
type: SpeciesReference

705166
stoichiometry: 1.0
species: 302606
type: SpeciesReference

302470
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Methyltetrahydrofolate_C20H24N7O6
type: Species

711807
stoichiometry: 1.0
species: 302728
type: SpeciesReference

304145
value: 0.0
type: LocalParameter

708783
stoichiometry: 1.0
species: 302655
type: SpeciesReference

719026
stoichiometry: 1.0
species: 302923
type: SpeciesReference

303847
value: -999999.0
type: LocalParameter

717613
stoichiometry: 1.0
species: 302460
type: SpeciesReference

696360
stoichiometry: 1.0
species: 302723
type: SpeciesReference

304963
value: 999999.0
type: LocalParameter

305569
value: 0.0
type: LocalParameter

712315
stoichiometry: 1.0
species: 302853
type: SpeciesReference

701624
stoichiometry: 1.0
species: 302723
type: SpeciesReference

702168
stoichiometry: 1.0
species: 302725
type: SpeciesReference

304855
value: 0.0
type: LocalParameter

718178
stoichiometry: 1.0
species: 302865
type: SpeciesReference

305356
value: 999999.0
type: LocalParameter

304960
value: 0.0
type: LocalParameter

706160
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305243
value: 0.0
type: LocalParameter

303102
kinetic law: 695819
product: 695807
reactant: 695795
reactant: 695783
notes: Abbreviation: R_ADK1 Synonyms: _0 EC Number: 2.7.4.3 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : amp + atp <==> (2) adp Confidence Level: 2 Inorganic triphosphate can also act as donor genes: LOCUS:BLBBGE_215#ABBREVIATION:adk#ECNUMBERS:2.7.4.3# proteins: NAME:Adenylate kinase#ABBREVIATION:Adk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_215)
fast: false
reversible: true
name: adenylate kinase
type: Reaction

715081
stoichiometry: 1.0
species: 302458
type: SpeciesReference

304146
value: 0.0
type: LocalParameter

303193
product: 700331
kinetic law: 700343
reactant: 700271
reactant: 700259
type: Reaction
fast: false
product: 700307
reversible: false
notes: Abbreviation: R_CYSabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + cys-L[e] + h2o[c] --> adp[c] + cys-L[c] + h[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 700319
reactant: 700283
name: L-cysteine transport via ABC system
product: 700295

305009
value: 999999.0
type: LocalParameter

708055
stoichiometry: 1.0
species: 302628
type: SpeciesReference

695663
stoichiometry: 1.0
species: 302451
type: SpeciesReference

303946
value: 0.0
type: LocalParameter

708262
stoichiometry: 1.0
species: 302526
type: SpeciesReference

707328
stoichiometry: 1.0
species: 302667
type: SpeciesReference

304413
value: -999999.0
type: LocalParameter

704901
stoichiometry: 1.0
species: 302601
type: SpeciesReference

304858
value: 0.0
type: LocalParameter

304402
value: 0.0
type: LocalParameter

696955
stoichiometry: 1.0
species: 302506
type: SpeciesReference

305357
value: 0.0
type: LocalParameter

304200
value: 0.0
type: LocalParameter

304401
value: 0.0
type: LocalParameter

304961
value: 0.0
type: LocalParameter

699863
stoichiometry: 1.0
species: 302853
type: SpeciesReference

303256
product: 702603
product: 702590
kinetic law: 702615
product: 702578
fast: false
notes: Abbreviation: R_DPCOAK Synonyms: _0 EC Number: 2.7.1.24 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + dpcoa --> adp + coa + h Confidence Level: 2 genes: LOCUS:BLBBGE_196#ABBREVIATION:coaE#ECNUMBERS:2.7.1.24# proteins: NAME:dephospho-CoA kinase#ABBREVIATION:CoaE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_196)
reversible: false
reactant: 702554
reactant: 702566
type: Reaction
name: dephospho-CoA kinase

303103
product: 695867
name: adentylate kinase (GTP)
product: 695855
reactant: 695831
fast: false
kinetic law: 695879
reactant: 695843
reversible: true
type: Reaction
notes: Abbreviation: R_ADK3 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : amp + gtp <==> adp + gdp Confidence Level: 2 JLR genes: LOCUS:BLBBGE_215#ABBREVIATION:adk#ECNUMBERS:2.7.4.3# proteins: NAME:Adenylate kinase#ABBREVIATION:Adk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_215)

305244
value: 999999.0
type: LocalParameter

719932
stoichiometry: 1.0
species: 302898
type: SpeciesReference

303047
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Sodium_Na
type: Species

714553
stoichiometry: 1.0
species: 302621
type: SpeciesReference

704768
stoichiometry: 1.0
species: 303072
type: SpeciesReference

718966
stoichiometry: 1.0
species: 302865
type: SpeciesReference

715297
stoichiometry: 1.0
species: 302738
type: SpeciesReference

720054
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304414
value: 999999.0
type: LocalParameter

708892
stoichiometry: 1.0
species: 302723
type: SpeciesReference

708116
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302990
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: UTP_C9H11N2O15P3
type: Species

303849
value: 0.0
type: LocalParameter

304857
value: 999999.0
type: LocalParameter

303610
product: 713189
kinetic law: 713201
reactant: 713153
name: Nucleoside triphosphate pyrophosphorylase (dttp)
reactant: 713140
notes: Abbreviation: R_NTPP7 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dttp + h2o --> dtmp + h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
type: Reaction
reversible: false
fast: false
product: 713177
product: 713165

302914
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-Succinyl-2-L-amino-6-oxoheptanedioate_C11H12NO8
type: Species

703412
stoichiometry: 1.0
species: 303013
type: SpeciesReference

713104
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304148
value: 0.0
type: LocalParameter

304852
value: 0.0
type: LocalParameter

303199
fast: false
name: cytidine deaminase
reactant: 700607
product: 700631
kinetic law: 700643
notes: Abbreviation: R_CYTD Synonyms: _0 EC Number: 3.5.4.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : cytd + h + h2o --> nh4 + uri Confidence Level: 2 genes: LOCUS:BLBBGE_495#ABBREVIATION:cdd#ECNUMBERS:3.5.4.5# proteins: NAME:cytidine/deoxycytidine deaminase#ABBREVIATION:Cdd# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_495)
reactant: 700595
product: 700619
reversible: false
reactant: 700583
type: Reaction

303046
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Methionine_C5H11NO2S
type: Species

710379
stoichiometry: 1.0
species: 302708
type: SpeciesReference

305358
value: 0.0
type: LocalParameter

712048
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304966
value: -999999.0
type: LocalParameter

698485
stoichiometry: 0.203
species: 302651
type: SpeciesReference

713999
stoichiometry: 1.0
species: 302980
type: SpeciesReference

303104
reactant: 695903
product: 695915
reversible: true
name: adentylate kinase (ITP)
reactant: 695891
kinetic law: 695939
product: 695927
fast: false
type: Reaction
notes: Abbreviation: R_ADK4 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : amp + itp <==> adp + idp Confidence Level: 2 JLR genes: LOCUS:BLBBGE_215#ABBREVIATION:adk#ECNUMBERS:2.7.4.3# proteins: NAME:Adenylate kinase#ABBREVIATION:Adk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_215)

702978
stoichiometry: 1.0
species: 302620
type: SpeciesReference

302993
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Valine_C5H11NO2
type: Species

303844
value: 999999.0
type: LocalParameter

711457
stoichiometry: 1.0
species: 302583
type: SpeciesReference

305003
value: 999999.0
type: LocalParameter

303940
value: 0.0
type: LocalParameter

305689
value: 0.0
type: LocalParameter

709364
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302915
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Sulfite_O3S
type: Species

706955
stoichiometry: 1.0
species: 302613
type: SpeciesReference

719074
stoichiometry: 2.0
species: 302659
type: SpeciesReference

303045
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Malate_C4H4O5
type: Species

304851
value: 999999.0
type: LocalParameter

698413
stoichiometry: 0.0135
species: 302565
type: SpeciesReference

303198
fast: false
name: cytochrome oxidase bo3 (ubiquinol-8: 2.5 protons)
product: 700559
product: 700547
product: 700535
reversible: false
reactant: 700511
reactant: 700499
reactant: 700523
kinetic law: 700571
type: Reaction
notes: Abbreviation: R_CYTBO3 Synonyms: _0 SUBSYSTEM: Oxidative Phosphorylation Equation: (2.5) h[c] + (0.5) o2[c] + mql8[c] --> (2.5) h[e] + h2o[c] + mqn8[c] Confidence Level: 2 EC Number: 1.9.3.1 genes: LOCUS:BLBBGE_414#ABBREVIATION:cyoC#ECNUMBERS:1.9.3.1# LOCUS:BLBBGE_416#ABBREVIATION:cyoBA#ECNUMBERS:1.9.3.1# proteins: NAME:cytochrome oxidase bo3#ABBREVIATION:CyoABC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_414 and BLBBGE_416)

697028
stoichiometry: 1.0
species: 302504
type: SpeciesReference

701987
stoichiometry: 1.0
species: 302473
type: SpeciesReference

305359
value: 0.0
type: LocalParameter

304967
value: 999999.0
type: LocalParameter

701309
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303941
value: 0.0
type: LocalParameter

696252
stoichiometry: 2.0
species: 302659
type: SpeciesReference

305004
value: 0.0
type: LocalParameter

302995
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Xanthine_C5H4N4O2
type: Species

304741
value: 999999.0
type: LocalParameter

710646
stoichiometry: 1.0
species: 302709
type: SpeciesReference

304964
value: 0.0
type: LocalParameter

303942
value: 999999.0
type: LocalParameter

303846
value: 0.0
type: LocalParameter

305005
value: 0.0
type: LocalParameter

709424
stoichiometry: 1.0
species: 302693
type: SpeciesReference

305240
value: 999999.0
type: LocalParameter

302913
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-Succinyl-LL-2,6-diaminoheptanedioate_C11H16N2O7
type: Species

303252
fast: false
notes: Abbreviation: R_DNMPPA Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : dhpmp + h2o --> dhnpt + pi Confidence Level: 1 JLR- Neidhardt page 667 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 702422
kinetic law: 702470
product: 702458
type: Reaction
name: Dihydroneopterin monophosphate dephosphorylase
reversible: false
product: 702446
reactant: 702434

696577
stoichiometry: 1.0
species: 302662
type: SpeciesReference

697979
stoichiometry: 1.0
species: 302493
type: SpeciesReference

715417
stoichiometry: 1.0
species: 302458
type: SpeciesReference

304410
value: 999999.0
type: LocalParameter

302994
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Valine_C5H11NO2
type: Species

304853
value: 0.0
type: LocalParameter

303107
name: adenosine kinase
fast: false
reversible: true
product: 695975
product: 695987
type: Reaction
notes: Abbreviation: R_ADNK1 Synonyms: _0 EC Number: 2.7.1.20 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : adn + atp <==> adp + amp + h Confidence Level: 2 _2-Aminoadenosine can also act as acceptor genes: LOCUS:BLBBGE_215#ABBREVIATION:adk#ECNUMBERS:2.7.4.3# proteins: NAME:Adenylate kinase#ABBREVIATION:Adk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_215)
product: 695999
reactant: 695963
kinetic law: 696011
reactant: 695951

304965
value: 0.0
type: LocalParameter

720584
stoichiometry: 1.0
species: 302905
type: SpeciesReference

303845
value: 0.0
type: LocalParameter

303943
value: 0.0
type: LocalParameter

302689
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: potassium_K
type: Species

715839
stoichiometry: 1.0
species: 302420
type: SpeciesReference

721671
stoichiometry: 1.0
species: 302493
type: SpeciesReference

708565
stoichiometry: 1.0
species: 302579
type: SpeciesReference

305722
value: 0.0
type: LocalParameter

302466
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (R)-5-Diphosphomevalonate_C6H10O10P2
type: Species

700921
stoichiometry: 1.0
species: 302526
type: SpeciesReference

707908
stoichiometry: 1.0
species: 302500
type: SpeciesReference

305573
value: 999999.0
type: LocalParameter

303697
kinetic law: 716309
product: 716297
reactant: 716285
notes: Abbreviation: R_PRMICIi Synonyms: _0 EC Number: 5.3.1.16 SUBSYSTEM: Histidine Metabolism Equation: [c] : prfp --> prlp Confidence Level: 2 JLR - added irreversible form of PRMICI genes: LOCUS:BLBBGE_438#ABBREVIATION:hisA#ECNUMBERS:5.3.1.16# proteins: NAME:Phosphoribosylformimino-5-amino-1-phosphoribosyl-4-imidazole carboxamide#ABBREVIATION:HisA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_438)
fast: false
reversible: false
name: _1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (irreversible)
type: Reaction

715637
stoichiometry: 1.0
species: 302769
type: SpeciesReference

700463
stoichiometry: 1.0
species: 302725
type: SpeciesReference

705384
stoichiometry: 1.0
species: 302493
type: SpeciesReference

711093
stoichiometry: 1.0
species: 302526
type: SpeciesReference

305698
value: 0.0
type: LocalParameter

305460
value: 999999.0
type: LocalParameter

305723
value: -999999.0
type: LocalParameter

706304
stoichiometry: 1.0
species: 302655
type: SpeciesReference

710327
stoichiometry: 1.0
species: 302705
type: SpeciesReference

711638
stoichiometry: 1.0
species: 302555
type: SpeciesReference

303619
type: Reaction
product: 713479
reactant: 713443
name: ornithine carbamoyltransferase
product: 713467
reversible: false
notes: Abbreviation: R_OCBT Synonyms: _0 EC Number: 2.1.3.3 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : cbp + orn --> citr-L + h + pi Confidence Level: 2 genes: LOCUS:BLBBGE_318#ABBREVIATION:argF#ECNUMBERS:2.1.3.3# proteins: NAME:Ornithine carbamoyl transferase II#ABBREVIATION:ArgF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_318)
kinetic law: 713503
fast: false
product: 713491
reactant: 713455

303249
product: 702397
name: dimethylallyltranstransferase
reactant: 702361
fast: false
type: Reaction
notes: Abbreviation: R_DMATT Synonyms: _0 EC Number: 2.5.1.1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : dmpp + ipdp --> grdp + ppi Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
kinetic law: 702410
reactant: 702373
reversible: false
product: 702385

717552
stoichiometry: 1.0
species: 302899
type: SpeciesReference

714889
stoichiometry: 1.0
species: 302855
type: SpeciesReference

722203
stoichiometry: 1.0
species: 302853
type: SpeciesReference

712461
stoichiometry: 1.0
species: 302550
type: SpeciesReference

716729
stoichiometry: 1.0
species: 302659
type: SpeciesReference

715790
stoichiometry: 1.0
species: 302659
type: SpeciesReference

701841
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304288
value: 999999.0
type: LocalParameter

707847
stoichiometry: 1.0
species: 302538
type: SpeciesReference

698848
stoichiometry: 1.0
species: 302655
type: SpeciesReference

708808
stoichiometry: 1.0
species: 302538
type: SpeciesReference

302465
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-phosphoribosyl-5-carboxyaminoimidazole_C9H11N3O9P
type: Species

303840
value: 0.0
type: LocalParameter

303618
kinetic law: 713431
product: 713419
reactant: 713407
notes: Abbreviation: R_O2t Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: o2[e] <==> o2[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: o2 transport (diffusion)
type: Reaction

707220
stoichiometry: 1.0
species: 302655
type: SpeciesReference

721040
stoichiometry: 1.0
species: 302964
type: SpeciesReference

305724
value: 999999.0
type: LocalParameter

303699
reactant: 716333
reversible: true
reactant: 716321
kinetic law: 716369
product: 716357
product: 716345
type: Reaction
name: L-proline reversible transport via proton symport
notes: Abbreviation: R_PROt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h[e] + pro-L[e] <==> h[c] + pro-L[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false

304969
value: 0.0
type: LocalParameter

704973
stoichiometry: 1.0
species: 302638
type: SpeciesReference

302998
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Xanthosine 5'-phosphate_C10H11N4O9P
type: Species

699645
stoichiometry: 2.0
species: 302655
type: SpeciesReference

699718
stoichiometry: 1.0
species: 302662
type: SpeciesReference

302905
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Serine_C3H7NO3
type: Species

717092
stoichiometry: 1.0
species: 302853
type: SpeciesReference

704654
stoichiometry: 1.0
species: 303067
type: SpeciesReference

714335
stoichiometry: 1.0
species: 302889
type: SpeciesReference

302464
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Amino-6-(5'-phosphoribosylamino)uracil_C9H13N4O9P
type: Species

302570
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Dihydroneopterin_C9H13N5O4
type: Species

303842
value: 0.0
type: LocalParameter

305725
value: 0.0
type: LocalParameter

707653
stoichiometry: 1.0
species: 302659
type: SpeciesReference

715564
stoichiometry: 1.0
species: 302720
type: SpeciesReference

709947
stoichiometry: 1.0
species: 302704
type: SpeciesReference

721101
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304968
value: 0.0
type: LocalParameter

695191
stoichiometry: 1.0
species: 302478
type: SpeciesReference

711891
stoichiometry: 1.0
species: 302865
type: SpeciesReference

304286
value: 0.0
type: LocalParameter

304620
value: 0.0
type: LocalParameter

302999
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Xanthosine_C10H12N4O6
type: Species

305461
value: 0.0
type: LocalParameter

305574
value: 0.0
type: LocalParameter

707994
stoichiometry: 1.0
species: 302724
type: SpeciesReference

302904
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: O-Succinylbenzoyl-CoA_C32H39N7O20P3S
type: Species

302571
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (S)-Dihydroorotate_C5H5N2O4
type: Species

302463
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Amino-6-(5'-phosphoribitylamino)uracil_C9H15N4O9P
type: Species

702458
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304859
value: 0.0
type: LocalParameter

700523
stoichiometry: 1.0
species: 302709
type: SpeciesReference

697188
stoichiometry: 1.0
species: 302709
type: SpeciesReference

305726
value: 0.0
type: LocalParameter

305694
value: 999999.0
type: LocalParameter

721307
stoichiometry: 1.0
species: 302969
type: SpeciesReference

304283
value: 0.0
type: LocalParameter

303190
fast: false
reactant: 700163
notes: Abbreviation: R_CTPS2 Synonyms: _0 EC Number: 6.3.4.2 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : atp + gln-L + h2o + utp --> adp + ctp + glu-L + (2) h + pi Confidence Level: 2 genes: LOCUS:BLBBGE_219#ABBREVIATION:pyrG#ECNUMBERS:6.3.4.2# proteins: NAME:CTP synthetase#ABBREVIATION:PyrG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_219)
reactant: 700175
product: 700199
product: 700187
product: 700235
reversible: false
kinetic law: 700247
product: 700223
name: CTP synthase (glutamine)
product: 700211
reactant: 700151
type: Reaction
reactant: 700139

302572
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: (S)-Dihydroorotate_C5H5N2O4
type: Species

711225
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305577
value: -999999.0
type: LocalParameter

303693
kinetic law: 715984
product: 715972
reactant: 715960
reactant: 715948
notes: Abbreviation: R_PRAMPC Synonyms: _0 EC Number: 3.5.4.19 SUBSYSTEM: Histidine Metabolism Equation: [c] : h2o + prbamp --> prfp Confidence Level: 2 genes: LOCUS:BLBBGE_440#ABBREVIATION:hisI#ECNUMBERS:3.5.4.19,-!-,3.6.1.31# proteins: NAME:Phosphoribosyl-ATP pyrophosphatase and -AMP cyclohydrolase#ABBREVIATION:HisI# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_440)
fast: false
reversible: false
name: phosphoribosyl-AMP cyclohydrolase
type: Reaction

303615
kinetic law: 713395
product: 713370
reactant: 713346
type: Reaction
fast: false
product: 713382
notes: Abbreviation: R_NTPTP2 Synonyms: _0 EC Number: 3.1.5.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : gtp + h2o --> gsn + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_612#ABBREVIATION:dgt#ECNUMBERS:3.1.5.1# proteins: NAME:putative transmembrane HD family protein#ABBREVIATION:Dgt# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_612)
name: Nucleoside triphosphate tripolyhydrolase
reactant: 713358
reversible: false

302686
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Inosine_C10H12N4O5
type: Species

697310
stoichiometry: 1.0
species: 302633
type: SpeciesReference

305727
value: -999999.0
type: LocalParameter

305693
value: -999999.0
type: LocalParameter

302461
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate_C9H11N3O9P
type: Species

303694
product: 716032
fast: false
name: phosphoribosylaminoimidazolesuccinocarboxamide synthase
product: 716044
reactant: 716008
notes: Abbreviation: R_PRASCS Synonyms: _0 EC Number: 6.3.2.6 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : 5aizc + asp-L + atp --> 25aics + adp + h + pi Confidence Level: 2 genes: LOCUS:BLBBGE_484#ABBREVIATION:purC#ECNUMBERS:6.3.2.6# proteins: NAME:phosphoribosyaminoimidazole-succinocarboxamide synthetase#ABBREVIATION:PurC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_484)
type: Reaction
reactant: 715996
reversible: false
reactant: 716020
product: 716056
product: 716068
kinetic law: 716080

701260
stoichiometry: 1.0
species: 302725
type: SpeciesReference

305576
value: 0.0
type: LocalParameter

304284
value: 0.0
type: LocalParameter

303248
kinetic law: 702349
product: 702337
product: 702325
reactant: 702313
notes: Abbreviation: R_DHQS Synonyms: _0 EC Number: 4.2.3.4 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : 2dda7p --> 3dhq + pi Confidence Level: 2 Previously EC 4.6.1.3. now EC 4.2.3.4, 3-dehydroquinate synthase genes: LOCUS:BLBBGE_493#ABBREVIATION:aroB#ECNUMBERS:4.6.1.3# proteins: NAME:_3-dehydroquinate synthase#ABBREVIATION:AroB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_493)
fast: false
reversible: false
name: _3-dehydroquinate synthase
type: Reaction

303614
reactant: 713286
type: Reaction
notes: Abbreviation: R_NTPTP1 Synonyms: _0 EC Number: 3.1.5.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dgtp + h2o --> dgsn + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_612#ABBREVIATION:dgt#ECNUMBERS:3.1.5.1# proteins: NAME:putative transmembrane HD family protein#ABBREVIATION:Dgt# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_612)
name: Nucleoside triphosphate tripolyhydrolase
reactant: 713298
kinetic law: 713334
reversible: false
product: 713310
fast: false
product: 713322

305579
value: 0.0
type: LocalParameter

305728
value: 999999.0
type: LocalParameter

720366
stoichiometry: 1.0
species: 302724
type: SpeciesReference

705715
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302687
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Isopentenyl diphosphate_C5H9O7P2
type: Species

717889
stoichiometry: 1.0
species: 302949
type: SpeciesReference

302574
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Dihydroneopterin monophosphate_C9H12N5O7P
type: Species

305696
value: 0.0
type: LocalParameter

302460
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _4-(1-D-Ribitylamino)-5-aminouracil_C9H16N4O6
type: Species

720427
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304281
value: 0.0
type: LocalParameter

704213
stoichiometry: 1.0
species: 303047
type: SpeciesReference

302909
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Shikimate 5-phosphate_C7H8O8P
type: Species

303695
product: 716116
kinetic law: 716152
fast: false
reactant: 716104
product: 716140
notes: Abbreviation: R_PRATPP Synonyms: _0 EC Number: 3.6.1.31 SUBSYSTEM: Histidine Metabolism Equation: [c] : h2o + prbatp --> h + ppi + prbamp Confidence Level: 2 genes: LOCUS:BLBBGE_440#ABBREVIATION:hisI#ECNUMBERS:3.5.4.19,-!-,3.6.1.31# proteins: NAME:Phosphoribosyl-ATP pyrophosphatase and -AMP cyclohydrolase#ABBREVIATION:HisI# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_440)
reactant: 716092
reversible: false
product: 716128
name: phosphoribosyl-ATP pyrophosphatase
type: Reaction

716453
stoichiometry: 1.0
species: 302760
type: SpeciesReference

709159
stoichiometry: 1.0
species: 302560
type: SpeciesReference

303247
kinetic law: 702301
product: 702289
product: 702277
reactant: 702265
notes: Abbreviation: R_DHQD Synonyms: _0 EC Number: 4.2.1.10 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : 3dhq <==> 3dhsk + h2o Confidence Level: 2 genes: LOCUS:BLBBGE_083#ABBREVIATION:aroD#ECNUMBERS:4.2.1.10# proteins: NAME:_3-dehydroquinate dehydratase#ABBREVIATION:AroD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_083)
fast: false
reversible: true
name: _3-dehydroquinate dehydratase
type: Reaction

305729
value: 0.0
type: LocalParameter

694924
stoichiometry: 1.0
species: 302480
type: SpeciesReference

302688
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: ITP_C10H11N4O14P3
type: Species

717224
stoichiometry: 1.0
species: 302895
type: SpeciesReference

710851
stoichiometry: 1.0
species: 302422
type: SpeciesReference

302575
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Dihydropteroate_C14H13N6O3
type: Species

718480
stoichiometry: 1.0
species: 302713
type: SpeciesReference

304282
value: 999999.0
type: LocalParameter

302908
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Serine_C3H7NO3
type: Species

305695
value: 0.0
type: LocalParameter

695227
stoichiometry: 1.0
species: 302485
type: SpeciesReference

305578
value: 999999.0
type: LocalParameter

303696
product: 716213
fast: false
reactant: 716165
type: Reaction
kinetic law: 716273
product: 716249
notes: Abbreviation: R_PRFGS Synonyms: _0 EC Number: 6.3.5.3 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : atp + fgam + gln-L + h2o --> adp + fpram + glu-L + h + pi Confidence Level: 2 genes: LOCUS:BLBBGE_486#ABBREVIATION:purL#ECNUMBERS:6.3.5.3# proteins: NAME:Phosphoribosylformylglycineamide synthetase#ABBREVIATION:PurL# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_486)
name: phosphoribosylformylglycinamidine synthase
product: 716261
reactant: 716177
product: 716225
reversible: false
product: 716237
reactant: 716189
reactant: 716201

701150
stoichiometry: 1.0
species: 302900
type: SpeciesReference

696505
stoichiometry: 1.0
species: 302498
type: SpeciesReference

305468
value: -999999.0
type: LocalParameter

700861
stoichiometry: 1.0
species: 302659
type: SpeciesReference

705009
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305690
value: 999999.0
type: LocalParameter

701489
stoichiometry: 1.0
species: 302411
type: SpeciesReference

302576
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Deoxyinosine_C10H12N4O4
type: Species

715726
stoichiometry: 1.0
species: 302526
type: SpeciesReference

698970
stoichiometry: 4.0
species: 302536
type: SpeciesReference

304625
value: 999999.0
type: LocalParameter

303507
notes: Abbreviation: R_MCOATA Synonyms: _2 EC Number: 2.3.1.39 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : ACP + malcoa --> coa + malACP Confidence Level: 2 tv genes: LOCUS:BLBBGE_538#ABBREVIATION:fabD#ECNUMBERS:2.3.1.39# proteins: NAME:Malonyl coenzyme A-acyl carrier protein transacylase#ABBREVIATION:FabD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_538)
fast: false
type: Reaction
reactant: 709727
reversible: false
kinetic law: 709764
name: Malonyl-CoA-ACP transacylase
reactant: 709715
product: 709739
product: 709752

304347
value: 0.0
type: LocalParameter

716393
stoichiometry: 1.0
species: 302898
type: SpeciesReference

304346
value: 999999.0
type: LocalParameter

713842
stoichiometry: 1.0
species: 302880
type: SpeciesReference

712157
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305467
value: 0.0
type: LocalParameter

303354
kinetic law: 704706
product: 704693
reactant: 704680
notes: Abbreviation: R_EX_thm_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : thm <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Thiamin exchange
type: Reaction

711385
stoichiometry: 1.0
species: 302526
type: SpeciesReference

719653
stoichiometry: 1.0
species: 302938
type: SpeciesReference

302682
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-(Imidazol-4-yl)-2-oxopropyl phosphate_C6H7N2O5P
type: Species

304064
value: 0.0
type: LocalParameter

717805
stoichiometry: 1.0
species: 302626
type: SpeciesReference

302577
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _6,7-Dimethyl-8-(1-D-ribityl)lumazine_C13H18N4O6
type: Species

706389
stoichiometry: 1.0
species: 302633
type: SpeciesReference

698039
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303506
notes: Abbreviation: R_MALt2_2 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: (2) h[e] + mal-L[e] --> (2) h[c] + mal-L[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_358#ABBREVIATION:dctA# proteins: NAME:C4-dicarboxylate transporter#ABBREVIATION:DctA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_358)
reversible: false
name: Malate transport via proton symport (2 H)
type: Reaction
kinetic law: 709703
product: 709690
reactant: 709666
reactant: 709653
product: 709678
fast: false

700679
stoichiometry: 1.0
species: 302534
type: SpeciesReference

304626
value: 0.0
type: LocalParameter

695117
stoichiometry: 2.0
species: 302893
type: SpeciesReference

304571
value: 0.0
type: LocalParameter

303586
kinetic law: 712388
fast: false
notes: Abbreviation: R_NTD4 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : cmp + h2o --> cytd + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 712364
type: Reaction
reactant: 712339
reactant: 712352
name: _5'-nucleotidase (CMP)
product: 712376
reversible: false

716429
stoichiometry: 1.0
species: 302880
type: SpeciesReference

302683
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: IMP_C10H11N4O8P
type: Species

305692
value: 0.0
type: LocalParameter

717020
stoichiometry: 1.0
species: 302564
type: SpeciesReference

699403
stoichiometry: 19.0
species: 302659
type: SpeciesReference

304627
value: 0.0
type: LocalParameter

303357
kinetic law: 704744
product: 704732
reactant: 704719
notes: Abbreviation: R_EX_thr_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : thr-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Threonine exchange
type: Reaction

305691
value: 0.0
type: LocalParameter

701599
stoichiometry: 1.0
species: 302659
type: SpeciesReference

704540
stoichiometry: 1.0
species: 303062
type: SpeciesReference

712740
stoichiometry: 1.0
species: 302659
type: SpeciesReference

709086
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303587
notes: Abbreviation: R_NTD5 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Sugar Metabolism Equation: [c] : dtmp + h2o --> pi + thymd Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
type: Reaction
product: 712425
reversible: false
product: 712437
fast: false
kinetic law: 712449
reactant: 712401
name: _5'-nucleotidase (dTMP)
reactant: 712413

304570
value: 999999.0
type: LocalParameter

704492
stoichiometry: 1.0
species: 302879
type: SpeciesReference

302684
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Indole_C8H7N
type: Species

698558
stoichiometry: 0.146
species: 302702
type: SpeciesReference

304066
value: 999999.0
type: LocalParameter

699947
stoichiometry: 1.0
species: 302537
type: SpeciesReference

710140
stoichiometry: 1.0
species: 302934
type: SpeciesReference

720210
stoichiometry: 1.0
species: 302945
type: SpeciesReference

710960
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302579
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Dimethylallyl diphosphate_C5H9O7P2
type: Species

701078
stoichiometry: 1.0
species: 302541
type: SpeciesReference

304348
value: 0.0
type: LocalParameter

304628
value: 0.0
type: LocalParameter

305469
value: 999999.0
type: LocalParameter

703629
stoichiometry: 1.0
species: 303023
type: SpeciesReference

700703
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303730
product: 717973
reversible: false
kinetic law: 718009
name: ribonucleoside-diphosphate reductase (UDP)
reactant: 717949
product: 717997
reactant: 717961
notes: Abbreviation: R_RNDR4 Synonyms: _0 EC Number: 1.17.4.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : trdrd + udp --> dudp + h2o + trdox Confidence Level: 2 genes: LOCUS:BLBBGE_310#ABBREVIATION:nrdA#ECNUMBERS:1.17.4.1# LOCUS:BLBBGE_p006#ABBREVIATION:nrdF#ECNUMBERS:1.17.4.1# proteins: NAME:ribonucleoside-diphosphate reductase subunit alpha#ABBREVIATION:NrdA# NAME:ribonucleotide-diphosphate reductase beta subunit#ABBREVIATION:NrdF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_310 and BLBBGE_p006)
product: 717985
fast: false
type: Reaction

708916
stoichiometry: 1.0
species: 302418
type: SpeciesReference

706473
stoichiometry: 1.0
species: 302640
type: SpeciesReference

705679
stoichiometry: 1.0
species: 302630
type: SpeciesReference

304067
value: 0.0
type: LocalParameter

305464
value: -999999.0
type: LocalParameter

304573
value: 0.0
type: LocalParameter

720713
stoichiometry: 1.0
species: 302659
type: SpeciesReference

706533
stoichiometry: 1.0
species: 302934
type: SpeciesReference

304621
value: 999999.0
type: LocalParameter

711153
stoichiometry: 1.0
species: 302729
type: SpeciesReference

711008
stoichiometry: 1.0
species: 302580
type: SpeciesReference

712946
stoichiometry: 1.0
species: 302534
type: SpeciesReference

304068
value: 0.0
type: LocalParameter

703593
stoichiometry: 1.0
species: 303020
type: SpeciesReference

705643
stoichiometry: 1.0
species: 302566
type: SpeciesReference

702651
stoichiometry: 1.0
species: 302493
type: SpeciesReference

305463
value: 0.0
type: LocalParameter

304572
value: 0.0
type: LocalParameter

706605
stoichiometry: 1.0
species: 302646
type: SpeciesReference

700355
stoichiometry: 1.0
species: 302488
type: SpeciesReference

701732
stoichiometry: 1.0
species: 302567
type: SpeciesReference

304622
value: 0.0
type: LocalParameter

717443
stoichiometry: 1.0
species: 302853
type: SpeciesReference

303358
kinetic law: 704780
product: 704768
reactant: 704756
notes: Abbreviation: R_EX_trp_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : trp-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Tryptophan exchange
type: Reaction

714251
stoichiometry: 1.0
species: 302479
type: SpeciesReference

303731
kinetic law: 718046
product: 718034
reactant: 718022
notes: Abbreviation: R_RPE Synonyms: _0 EC Number: 5.1.3.1 SUBSYSTEM: Pentose Phosphate Pathway Equation: [c] : ru5p-D <==> xu5p-D Confidence Level: 2 SMP genes: LOCUS:BLBBGE_347#ABBREVIATION:rpe#ECNUMBERS:5.1.3.1# proteins: NAME:D-ribulose-5-phosphate 3-epimerase#ABBREVIATION:Rpe# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_347)
fast: false
reversible: true
name: ribulose 5-phosphate 3-epimerase
type: Reaction

717733
stoichiometry: 1.0
species: 302493
type: SpeciesReference

302469
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Formyltetrahydrofolate_C20H21N7O7
type: Species

305720
value: 0.0
type: LocalParameter

304069
value: 0.0
type: LocalParameter

721524
stoichiometry: 1.0
species: 302659
type: SpeciesReference

721949
stoichiometry: 2.0
species: 302725
type: SpeciesReference

302769
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Phenylpyruvate_C9H7O3
type: Species

305466
value: 0.0
type: LocalParameter

304575
value: 0.0
type: LocalParameter

305571
value: 0.0
type: LocalParameter

304289
value: 0.0
type: LocalParameter

715153
stoichiometry: 1.0
species: 302713
type: SpeciesReference

304623
value: 0.0
type: LocalParameter

302468
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-enolpyruvoyl-6-hydroxy-2-succinyl-3-cyclohexene-1-carboxylate_C14H14O9
type: Species

303732
kinetic law: 718082
product: 718070
reactant: 718058
notes: Abbreviation: R_RPI Synonyms: _0 EC Number: 5.3.1.6 SUBSYSTEM: Pentose Phosphate Pathway Equation: [c] : r5p <==> ru5p-D Confidence Level: 2 SMP genes: LOCUS:BLBBGE_295#ABBREVIATION:rpiB#ECNUMBERS:5.3.1.6,-!-,5.3.1.-# proteins: NAME:ribose-5-phosphate isomerase B#ABBREVIATION:RpiB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_295)
fast: false
reversible: true
name: ribose-5-phosphate isomerase
type: Reaction

719569
stoichiometry: 1.0
species: 302928
type: SpeciesReference

714445
stoichiometry: 1.0
species: 302758
type: SpeciesReference

302680
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Isoleucine_C6H13NO2
type: Species

304574
value: 999999.0
type: LocalParameter

305465
value: 999999.0
type: LocalParameter

302768
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: O-Phospho-L-homoserine_C4H8NO6P
type: Species

720648
stoichiometry: 1.0
species: 302620
type: SpeciesReference

702385
stoichiometry: 1.0
species: 302649
type: SpeciesReference

304624
value: -999999.0
type: LocalParameter

303733
fast: false
reactant: 718106
reactant: 718130
reversible: true
product: 718154
name: Sulfate adenyltransferase
product: 718142
reactant: 718094
type: Reaction
reactant: 718118
kinetic law: 718190
product: 718178
notes: Abbreviation: R_SADT2 Synonyms: _1 SUBSYSTEM: Cysteine Metabolism Equation: [c] : atp + gtp + h2o + so4 <==> aps + gdp + pi + ppi Confidence Level: 2 tv genes: LOCUS:BLBBGE_275#ABBREVIATION:cysN#ECNUMBERS:2.7.7.4# LOCUS:BLBBGE_274#ABBREVIATION:cysD#ECNUMBERS:2.7.7.4# proteins: NAME:ATP-sulfurylase#ABBREVIATION:CysND# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_275 and BLBBGE_274)
product: 718166

305235
value: 999999.0
type: LocalParameter

304344
value: 0.0
type: LocalParameter

305388
value: 0.0
type: LocalParameter

304882
value: -999999.0
type: LocalParameter

303583
kinetic law: 712327
product: 712315
type: Reaction
reversible: false
reactant: 712291
name: _5'-nucleotidase (dCMP)
reactant: 712279
product: 712303
notes: Abbreviation: R_NTD3 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dcmp + h2o --> dcyt + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false

303782
notes: Abbreviation: R_TYRt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h[e] + tyr-L[e] <==> h[c] + tyr-L[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
product: 720775
reversible: true
fast: false
product: 720787
reactant: 720751
reactant: 720763
kinetic law: 720799
name: L-tyrosine reversible transport via proton symport
type: Reaction

304098
value: 0.0
type: LocalParameter

302709
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Menaquinol 8_C51H74O2
type: Species

304001
value: 0.0
type: LocalParameter

303072
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Tryptophan_C11H12N2O2
type: Species

303705
notes: Abbreviation: R_PSP_L Synonyms: _0 EC Number: 3.1.3.3 SUBSYSTEM: Glycine and Serine Metabolism Equation: [c] : h2o + pser-L --> pi + ser-L Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 716657
kinetic law: 716681
type: Reaction
fast: false
reactant: 716645
reactant: 716633
product: 716669
reversible: false
name: phosphoserine phosphatase (L-serine)

720174
stoichiometry: 1.0
species: 302939
type: SpeciesReference

715009
stoichiometry: 1.0
species: 302526
type: SpeciesReference

708383
stoichiometry: 1.0
species: 302445
type: SpeciesReference

305033
value: 0.0
type: LocalParameter

303938
value: 999999.0
type: LocalParameter

304558
value: 999999.0
type: LocalParameter

305449
value: -999999.0
type: LocalParameter

303426
kinetic law: 706919
type: Reaction
reactant: 706835
name: GMP synthase
reversible: false
reactant: 706847
product: 706883
product: 706895
product: 706871
reactant: 706823
reactant: 706811
product: 706859
product: 706907
fast: false
notes: Abbreviation: R_GMPS2 Synonyms: _0 EC Number: 6.3.5.2 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : atp + gln-L + h2o + xmp --> amp + glu-L + gmp + (2) h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_478#ABBREVIATION:guaA#ECNUMBERS:6.3.5.2,-!-,6.3.4.1# proteins: NAME:GMP synthase#ABBREVIATION:GuaA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_478)

712704
stoichiometry: 1.0
species: 302565
type: SpeciesReference

699596
stoichiometry: 15.0
species: 302723
type: SpeciesReference

304737
value: 0.0
type: LocalParameter

304881
value: 0.0
type: LocalParameter

304345
value: -999999.0
type: LocalParameter

305389
value: 0.0
type: LocalParameter

305236
value: 0.0
type: LocalParameter

304680
value: 0.0
type: LocalParameter

699742
stoichiometry: 1.0
species: 302527
type: SpeciesReference

303377
kinetic law: 705275
fast: false
reactant: 705227
name: aminomethyltransferase
product: 705251
reactant: 705239
notes: Abbreviation: R_FOMETR Synonyms: _0 EC Number: 2.1.2.10 SUBSYSTEM: Cofactor Metabolism Equation: [c] : 5fthf + h <==> h2o + methf Confidence Level: 2 RM genes: LOCUS:BLBBGE_188#ABBREVIATION:gcvT#ECNUMBERS:2.1.2.10# proteins: NAME:Glycine cleavage complex, T#ABBREVIATION:GcvT# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_188)
type: Reaction
product: 705263
reversible: true

303582
name: _5'-nucleotidase (UMP)
notes: Abbreviation: R_NTD2 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : h2o + ump --> pi + uri Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
type: Reaction
product: 712255
fast: false
reactant: 712218
reactant: 712230
kinetic law: 712267
reversible: false
product: 712243

303783
reversible: true
reactant: 720823
product: 720835
name: tyrosine transaminase
notes: Abbreviation: R_TYRTA Synonyms: _13 EC Number: 2.6.1.5 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : akg + tyr-L <==> 34hpp + glu-L Confidence Level: 2 genes: LOCUS:BLBBGE_355#ABBREVIATION:aspC#ECNUMBERS:2.6.1.1# LOCUS:BLBBGE_342#ABBREVIATION:tyrB#ECNUMBERS:2.6.1.57# proteins: NAME:Tyrosine aminotransferase#ABBREVIATION:TyrB# NAME:aspartate aminotransferase#ABBREVIATION:AspC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_342) or (BLBBGE_355)
kinetic law: 720859
type: Reaction
product: 720847
fast: false
reactant: 720811

302708
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5,10-Methylenetetrahydrofolate_C20H21N7O6
type: Species

702880
stoichiometry: 1.0
species: 302984
type: SpeciesReference

304002
value: 999999.0
type: LocalParameter

304097
value: 0.0
type: LocalParameter

303071
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Threonine_C4H9NO3
type: Species

702735
stoichiometry: 1.0
species: 302493
type: SpeciesReference

303704
notes: Abbreviation: R_PSERT Synonyms: _0 EC Number: 2.6.1.52 SUBSYSTEM: Glycine and Serine Metabolism Equation: [c] : 3php + glu-L <==> akg + pser-L Confidence Level: 2 genes: LOCUS:BLBBGE_428#ABBREVIATION:serC#ECNUMBERS:2.6.1.52# LOCUS:BLBBGE_144#ABBREVIATION:serC#ECNUMBERS:2.6.1.52# proteins: NAME:Phosphoserine aminotransferase#ABBREVIATION:SerC# NAME:Phosphoserine aminotransferase#ABBREVIATION:SerC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_428) or (BLBBGE_144)
reactant: 716573
kinetic law: 716621
reactant: 716585
fast: false
reversible: true
product: 716609
type: Reaction
product: 716597
name: phosphoserine transaminase

302620
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Glyceraldehyde 3-phosphate_C3H5O6P
type: Species

707557
stoichiometry: 4.0
species: 302860
type: SpeciesReference

305034
value: 0.0
type: LocalParameter

303425
kinetic law: 706799
product: 706787
reactant: 706775
notes: Abbreviation: R_GLYt Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: gly[e] <==> gly[c] Confidence Level: 2 NCD genes: LOCUS:BLBBGE_460#ABBREVIATION:glpF# proteins: NAME:MIP channel, glycerol diffusion#ABBREVIATION:GlpF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_460)
fast: false
reversible: true
name: Glycine transport via diffusion
type: Reaction

303939
value: 0.0
type: LocalParameter

715466
stoichiometry: 1.0
species: 302534
type: SpeciesReference

304559
value: 0.0
type: LocalParameter

304736
value: 0.0
type: LocalParameter

305386
value: 999999.0
type: LocalParameter

304342
value: 999999.0
type: LocalParameter

305233
value: 0.0
type: LocalParameter

698509
stoichiometry: 0.09
species: 302666
type: SpeciesReference

303374
reversible: false
reactant: 705154
fast: false
product: 705203
name: FMN adenylyltransferase
reactant: 705179
notes: Abbreviation: R_FMNAT Synonyms: _0 EC Number: 2.7.7.2 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + fmn + h --> fad + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_072#ABBREVIATION:ribF#ECNUMBERS:2.7.1.26,-!-,2.7.7.2# proteins: NAME:Flavokinase and FAD synthetase#ABBREVIATION:RibF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_072)
kinetic law: 705215
type: Reaction
product: 705191
reactant: 705166

304096
value: 999999.0
type: LocalParameter

304880
value: 0.0
type: LocalParameter

715911
stoichiometry: 2.0
species: 302659
type: SpeciesReference

303784
reactant: 720883
notes: Abbreviation: R_UAAGDS Synonyms: _0 EC Number: 6.3.2.13 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : 26dap-M + atp + uamag --> adp + h + pi + ugmd Confidence Level: 2 genes: LOCUS:BLBBGE_390#ABBREVIATION:murE#ECNUMBERS:6.3.2.13# proteins: NAME:UDP-N-acetylmuramoxylalanyl-D-glutamate 2,6-diaminopimelate ligase#ABBREVIATION:MurE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_390)
reactant: 720895
product: 720919
reversible: false
kinetic law: 720956
fast: false
product: 720932
type: Reaction
product: 720907
product: 720944
reactant: 720871
name: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase

711927
stoichiometry: 1.0
species: 302659
type: SpeciesReference

714697
stoichiometry: 1.0
species: 302493
type: SpeciesReference

303936
value: 0.0
type: LocalParameter

709653
stoichiometry: 2.0
species: 302660
type: SpeciesReference

694766
stoichiometry: 1.0
species: 302452
type: SpeciesReference

304735
value: 999999.0
type: LocalParameter

305031
value: 999999.0
type: LocalParameter

701502
stoichiometry: 1.0
species: 302444
type: SpeciesReference

305447
value: 0.0
type: LocalParameter

704090
stoichiometry: 1.0
species: 302696
type: SpeciesReference

304556
value: 0.0
type: LocalParameter

304801
value: 0.0
type: LocalParameter

305387
value: 0.0
type: LocalParameter

304095
value: 0.0
type: LocalParameter

304343
value: 0.0
type: LocalParameter

304000
value: 0.0
type: LocalParameter

714601
stoichiometry: 1.0
species: 302719
type: SpeciesReference

303073
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Tyrosine_C9H11NO3
type: Species

697458
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302706
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (R)-mevalonate_C6H11O4
type: Species

716357
stoichiometry: 1.0
species: 302878
type: SpeciesReference

305032
value: 0.0
type: LocalParameter

696071
stoichiometry: 1.0
species: 302755
type: SpeciesReference

708662
stoichiometry: 1.0
species: 302435
type: SpeciesReference

303702
kinetic law: 716561
product: 716537
fast: false
reversible: false
notes: Abbreviation: R_PSD_Bge Synonyms: _0 EC Number: 4.1.1.65 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : h + (0.02) ps_Bge --> co2 + (0.02) pe_Bge Confidence Level: 2 JLR genes: LOCUS:BLBBGE_225#ABBREVIATION:psd#ECNUMBERS:4.1.1.65# proteins: NAME:Phosphatidylserine decarboxylase#ABBREVIATION:Psd# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_225)
reactant: 716513
reactant: 716525
product: 716549
name: Phosphatidylserine decarboxylase
type: Reaction

695603
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305448
value: 0.0
type: LocalParameter

304734
value: 0.0
type: LocalParameter

702289
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302705
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5,10-Methenyltetrahydrofolate_C20H20N7O6
type: Species

304005
value: 0.0
type: LocalParameter

707051
stoichiometry: 1.0
species: 302651
type: SpeciesReference

304094
value: 0.0
type: LocalParameter

304683
value: 0.0
type: LocalParameter

303076
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Urea_CH4N2O
type: Species

304340
value: 0.0
type: LocalParameter

304554
value: 0.0
type: LocalParameter

305384
value: 0.0
type: LocalParameter

303189
notes: Abbreviation: R_CSND Synonyms: _0 EC Number: 3.5.4.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : csn + h + h2o --> nh4 + ura Confidence Level: 2 JLR genes: LOCUS:BLBBGE_353#ABBREVIATION:codA#ECNUMBERS:3.5.4.1# proteins: NAME:cytosine deaminase#ABBREVIATION:CodA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_353)
product: 700115
name: Cytosine deaminase
fast: false
reactant: 700091
type: Reaction
reactant: 700067
reversible: false
reactant: 700079
kinetic law: 700127
product: 700103

304886
value: -999999.0
type: LocalParameter

304733
value: 0.0
type: LocalParameter

304803
value: 999999.0
type: LocalParameter

722167
stoichiometry: 1.0
species: 302994
type: SpeciesReference

305239
value: 0.0
type: LocalParameter

695251
stoichiometry: 1.0
species: 302475
type: SpeciesReference

719146
stoichiometry: 1.0
species: 302617
type: SpeciesReference

698691
stoichiometry: 0.205
species: 302905
type: SpeciesReference

717985
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305037
value: 0.0
type: LocalParameter

303701
reversible: false
fast: false
name: _3-phosphoshikimate 1-carboxyvinyltransferase
product: 716477
reactant: 716453
notes: Abbreviation: R_PSCVT Synonyms: _0 EC Number: 2.5.1.19 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : pep + skm5p --> 3psme + pi Confidence Level: 2 genes: LOCUS:BLBBGE_406#ABBREVIATION:aroA#ECNUMBERS:2.5.1.19# proteins: NAME:_3-phosphoshikimate 1-carboxyvinyltransferase#ABBREVIATION:AroA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_406)
type: Reaction
reactant: 716465
product: 716489
kinetic law: 716501

713382
stoichiometry: 1.0
species: 302865
type: SpeciesReference

696748
stoichiometry: 1.0
species: 302928
type: SpeciesReference

710213
stoichiometry: 2.0
species: 302659
type: SpeciesReference

303373
product: 705105
reactant: 705069
fast: false
name: iron (II) transport via ABC system
reversible: false
kinetic law: 705142
notes: Abbreviation: R_FE2abc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + fe2[e] + h2o[c] --> adp[c] + fe2[c] + h[c] + pi[c] Confidence Level: 2 genes: LOCUS:BLBBGE_127#ABBREVIATION:feoB# proteins: NAME:Iron(II) transport protein#ABBREVIATION:FeoB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_127)
product: 705118
reactant: 705057
product: 705093
product: 705130
reactant: 705081
type: Reaction

304093
value: 0.0
type: LocalParameter

697858
stoichiometry: 1.0
species: 302853
type: SpeciesReference

303188
reactant: 700007
fast: false
product: 700019
product: 700043
notes: Abbreviation: R_CS Synonyms: _0 SUBSYSTEM: Citric Acid Cycle Equation: [c] : accoa + h2o + oaa --> cit + coa + h Confidence Level: 2 old EC number (4.1.3.7) is obsolete -- transferred to 2.3.3.1 genes: LOCUS:BLBBGE_540#ABBREVIATION:gltA#ECNUMBERS:2.3.3.1# proteins: NAME:citrate synthase#ABBREVIATION:GltA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_540)
reversible: false
name: citrate synthase
reactant: 699983
kinetic law: 700055
type: Reaction
product: 700031
reactant: 699995

714119
stoichiometry: 0.14
species: 302664
type: SpeciesReference

304684
value: 0.0
type: LocalParameter

305385
value: 0.0
type: LocalParameter

302704
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Methionine_C5H11NO2S
type: Species

304341
value: 0.0
type: LocalParameter

304885
value: 0.0
type: LocalParameter

304732
value: 0.0
type: LocalParameter

698365
stoichiometry: 0.126
species: 302541
type: SpeciesReference

303429
product: 706955
type: Reaction
notes: Abbreviation: R_GRTT Synonyms: _0 EC Number: 2.5.1.10 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : grdp + ipdp --> frdp + ppi Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 706943
reactant: 706931
product: 706967
reversible: false
kinetic law: 706979
name: geranyltranstransferase
fast: false

304804
value: 0.0
type: LocalParameter

718685
stoichiometry: 1.0
species: 302910
type: SpeciesReference

701428
stoichiometry: 1.0
species: 302526
type: SpeciesReference

305038
value: 0.0
type: LocalParameter

304006
value: 999999.0
type: LocalParameter

303700
reactant: 716381
notes: Abbreviation: R_PRPPS Synonyms: _0 EC Number: 2.7.6.1 SUBSYSTEM: Histidine Metabolism Equation: [c] : atp + r5p --> amp + h + prpp Confidence Level: 2 genes: LOCUS:BLBBGE_497#ABBREVIATION:prsA#ECNUMBERS:2.7.6.1# proteins: NAME:phosphoribosylpyrophosphate synthetase#ABBREVIATION:PrsA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_497)
reactant: 716393
product: 716417
product: 716429
product: 716405
type: Reaction
reversible: false
kinetic law: 716441
fast: false
name: phosphoribosylpyrophosphate synthetase

711783
stoichiometry: 1.0
species: 302688
type: SpeciesReference

303370
reactant: 705009
product: 705033
kinetic law: 705045
product: 705021
reversible: false
notes: Abbreviation: R_FBP Synonyms: _0 EC Number: 3.1.3.11 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : fdp + h2o --> f6p + pi Confidence Level: 2 SMP genes: LOCUS:BLBBGE_509#ABBREVIATION:fbp#ECNUMBERS:3.1.3.11# proteins: NAME:fructose-1,6-bisphophatase#ABBREVIATION:Fbp# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_509)
reactant: 704997
fast: false
name: fructose-bisphosphatase
type: Reaction

305382
value: 0.0
type: LocalParameter

304003
value: 0.0
type: LocalParameter

713225
stoichiometry: 1.0
species: 302990
type: SpeciesReference

304731
value: 999999.0
type: LocalParameter

303078
name: _4-Hydroxy-L-threonine synthase
reactant: 694742
fast: false
kinetic law: 694790
reactant: 694754
reversible: false
product: 694778
notes: Abbreviation: R_4HTHRS Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : h2o + phthr --> 4hthr + pi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_499#ABBREVIATION:thrC#ECNUMBERS:4.2.3.1# proteins: NAME:Threonine synthase#ABBREVIATION:ThrC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_499)
product: 694766
type: Reaction

304884
value: 0.0
type: LocalParameter

304092
value: 999999.0
type: LocalParameter

304552
value: 999999.0
type: LocalParameter

713092
stoichiometry: 1.0
species: 302511
type: SpeciesReference

304681
value: 999999.0
type: LocalParameter

304805
value: 0.0
type: LocalParameter

305035
value: 999999.0
type: LocalParameter

303781
kinetic law: 720739
product: 720726
reactant: 720700
fast: false
reversible: true
type: Reaction
notes: Abbreviation: R_TRPt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h[e] + trp-L[e] <==> h[c] + trp-L[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 720687
name: L-tryptophan reversible transport via proton symport
product: 720713

304004
value: 0.0
type: LocalParameter

712073
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304553
value: 0.0
type: LocalParameter

304091
value: 0.0
type: LocalParameter

710766
stoichiometry: 1.0
species: 302422
type: SpeciesReference

302702
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Methionine_C5H11NO2S
type: Species

304730
value: -999999.0
type: LocalParameter

304883
value: 999999.0
type: LocalParameter

303077
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Valine_C5H11NO2
type: Species

304682
value: 0.0
type: LocalParameter

718034
stoichiometry: 1.0
species: 303000
type: SpeciesReference

707785
stoichiometry: 1.0
species: 302659
type: SpeciesReference

720980
stoichiometry: 1.0
species: 302964
type: SpeciesReference

305238
value: 0.0
type: LocalParameter

708710
stoichiometry: 1.0
species: 302426
type: SpeciesReference

302548
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dADP_C10H12N5O9P2
type: Species

305036
value: 0.0
type: LocalParameter

716633
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304806
value: 0.0
type: LocalParameter

303858
value: 0.0
type: LocalParameter

303930
value: 0.0
type: LocalParameter

304807
value: 999999.0
type: LocalParameter

698582
stoichiometry: 5.0E-5
species: 302720
type: SpeciesReference

716525
stoichiometry: 0.02
species: 302883
type: SpeciesReference

709436
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304952
value: 0.0
type: LocalParameter

303185
kinetic law: 699971
product: 699959
reactant: 699947
notes: Abbreviation: R_CO2t Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: co2[e] <==> co2[c] Confidence Level: 1 renamed from CO2TPr to CO2t genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: CO2 transporter via diffusion
type: Reaction

711855
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302924
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Succinate_C4H4O4
type: Species

304445
value: 0.0
type: LocalParameter

713443
stoichiometry: 1.0
species: 302527
type: SpeciesReference

710610
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304231
value: 0.0
type: LocalParameter

302701
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Malonyl-CoA_C24H33N7O19P3S
type: Species

304090
value: 0.0
type: LocalParameter

304114
value: 999999.0
type: LocalParameter

305655
value: 999999.0
type: LocalParameter

303857
value: 0.0
type: LocalParameter

305656
value: 0.0
type: LocalParameter

304808
value: 0.0
type: LocalParameter

303931
value: -999999.0
type: LocalParameter

304446
value: 999999.0
type: LocalParameter

304889
value: 0.0
type: LocalParameter

695927
stoichiometry: 1.0
species: 302678
type: SpeciesReference

304953
value: 0.0
type: LocalParameter

710366
stoichiometry: 1.0
species: 302659
type: SpeciesReference

696565
stoichiometry: 1.0
species: 302526
type: SpeciesReference

303642
reversible: false
reactant: 714239
type: Reaction
fast: false
name: pyruvate dehydrogenase
product: 714251
kinetic law: 714287
notes: Abbreviation: R_PDH Synonyms: _0 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : coa + nad + pyr --> accoa + co2 + nadh Confidence Level: 2 genes: LOCUS:BLBBGE_099#ABBREVIATION:pdhA#ECNUMBERS:1.2.4.1# LOCUS:BLBBGE_098#ABBREVIATION:aceF#ECNUMBERS:2.3.1.12# LOCUS:BLBBGE_147#ABBREVIATION:lpd#ECNUMBERS:1.8.1.4# LOCUS:BLBBGE_446#ABBREVIATION:pdhB#ECNUMBERS:1.2.4.1# proteins: NAME:pyruvate dehydrogenase E1 component subunit beta#ABBREVIATION:PdhB# NAME:dihydrolipoamide dehydrogenase#ABBREVIATION:LpdA# NAME:Pyruvate dehydrogenase, F#ABBREVIATION:AceF# NAME:pyruvate dehydrogenase E1 component subunit alpha#ABBREVIATION:PdhA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_099) and (BLBBGE_098) and (BLBBGE_147) and (BLBBGE_446)
reactant: 714215
product: 714263
product: 714275
reactant: 714227

700199
stoichiometry: 1.0
species: 302541
type: SpeciesReference

302700
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Malate_C4H4O5
type: Species

303184
product: 699923
kinetic law: 699935
product: 699911
reversible: false
reactant: 699887
name: CMP nucleosidase
notes: Abbreviation: R_CMPN Synonyms: _0 EC Number: 3.2.2.10 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : cmp + h2o --> csn + r5p Confidence Level: 1 JLR - also acts on dUMP, dCMP,dTMP, and presumably TMP and UMP genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reactant: 699899
type: Reaction

304232
value: 999999.0
type: LocalParameter

303079
reactant: 694814
product: 694839
reactant: 694826
kinetic law: 694888
fast: false
product: 694851
product: 694864
reactant: 694802
type: Reaction
notes: Abbreviation: R_ACCOACr Synonyms: _0 EC Number: 6.4.1.2 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : accoa + atp + hco3 --> adp + h + malcoa + pi Confidence Level: 2 NCD genes: LOCUS:BLBBGE_154#ABBREVIATION:accA#ECNUMBERS:6.4.1.2# LOCUS:BLBBGE_477#ABBREVIATION:accD#ECNUMBERS:6.4.1.2# LOCUS:BLBBGE_516#ABBREVIATION:accB# LOCUS:BLBBGE_517#ABBREVIATION:accC#ECNUMBERS:6.3.4.14# proteins: NAME:AcetylCoA carboxylase#ABBREVIATION:Acc# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_154 and BLBBGE_516 and BLBBGE_517 and BLBBGE_477)
reversible: false
name: acetyl-CoA carboxylase, reversible reaction
product: 694876

304115
value: 0.0
type: LocalParameter

699367
stoichiometry: 1.0
species: 302750
type: SpeciesReference

302925
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Succinate_C4H4O4
type: Species

304809
value: 0.0
type: LocalParameter

716128
stoichiometry: 1.0
species: 302865
type: SpeciesReference

303856
value: 999999.0
type: LocalParameter

305039
value: 999999.0
type: LocalParameter

698473
stoichiometry: 0.582
species: 302636
type: SpeciesReference

303643
product: 714335
name: pyridoxine 5'-phosphate oxidase
reactant: 714311
type: Reaction
product: 714323
kinetic law: 714347
reversible: false
notes: Abbreviation: R_PDX5PO Synonyms: _0 EC Number: 1.4.3.5 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : o2 + pdx5p --> h2o2 + pydx5p Confidence Level: 2 NCD genes: LOCUS:BLBBGE_050#ABBREVIATION:pdxH#ECNUMBERS:1.4.3.5# proteins: NAME:Pyridoxine 5-phosphate oxidase#ABBREVIATION:PdxH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_050)
fast: false
reactant: 714299

304954
value: -999999.0
type: LocalParameter

304888
value: 0.0
type: LocalParameter

695591
stoichiometry: 1.0
species: 302490
type: SpeciesReference

717371
stoichiometry: 1.0
species: 302493
type: SpeciesReference

716068
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304443
value: 0.0
type: LocalParameter

305653
value: 0.0
type: LocalParameter

304112
value: 0.0
type: LocalParameter

711421
stoichiometry: 1.0
species: 302541
type: SpeciesReference

303855
value: 0.0
type: LocalParameter

717901
stoichiometry: 1.0
species: 302555
type: SpeciesReference

696264
stoichiometry: 1.0
species: 302853
type: SpeciesReference

720871
stoichiometry: 1.0
species: 302417
type: SpeciesReference

304955
value: 999999.0
type: LocalParameter

701999
stoichiometry: 1.0
species: 302625
type: SpeciesReference

304887
value: 999999.0
type: LocalParameter

715093
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304230
value: 0.0
type: LocalParameter

304444
value: 0.0
type: LocalParameter

697016
stoichiometry: 1.0
species: 302500
type: SpeciesReference

304113
value: -999999.0
type: LocalParameter

304449
value: 0.0
type: LocalParameter

719376
stoichiometry: 1.0
species: 302853
type: SpeciesReference

303709
fast: false
reactant: 716838
reactant: 716850
type: Reaction
name: purine-nucleoside phosphorylase (Adenosine)
product: 716862
product: 716874
notes: Abbreviation: R_PUNP1 Synonyms: _0 EC Number: 2.4.2.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : adn + pi <==> ade + r1p Confidence Level: 2 Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase genes: LOCUS:BLBBGE_377#ABBREVIATION:pndA#ECNUMBERS:2.4.2.1# proteins: NAME:purine-nucleoside phosphorylase#ABBREVIATION:PndA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)
reversible: true
kinetic law: 716886

702205
stoichiometry: 1.0
species: 302474
type: SpeciesReference

305659
value: 0.0
type: LocalParameter

706907
stoichiometry: 1.0
species: 302865
type: SpeciesReference

695699
stoichiometry: 1.0
species: 302893
type: SpeciesReference

303786
notes: Abbreviation: R_UAGAAT Synonyms: _0 EC Number: 2.3.1.129 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : 3hmrsACP + uacgam <==> ACP + u3aga Confidence Level: 1 JLR- NH page 1041 genes: none proteins: none citations: none GENE ASSOCIATION:
name: UDP-N-acetylglucosamine acyltransferase
reactant: 720968
type: Reaction
product: 720992
kinetic law: 721016
reactant: 720980
reversible: true
product: 721004
fast: false

303934
value: 0.0
type: LocalParameter

303181
kinetic law: 699875
product: 699863
product: 699851
reactant: 699839
notes: Abbreviation: R_CHORS Synonyms: _0 EC Number: 4.2.3.5 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : 3psme --> chor + pi Confidence Level: 2 Previously EC 4.6.1.4. Now EC 4.2.3.5 genes: LOCUS:BLBBGE_185#ABBREVIATION:aroC#ECNUMBERS:4.2.3.5# proteins: NAME:Chorismate synthase#ABBREVIATION:AroC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_185)
fast: false
reversible: false
name: chorismate synthase
type: Reaction

304110
value: 999999.0
type: LocalParameter

721609
stoichiometry: 1.0
species: 302973
type: SpeciesReference

303422
product: 706751
product: 706739
reversible: false
fast: false
type: Reaction
product: 706727
notes: Abbreviation: R_GLYK Synonyms: _0 EC Number: 2.7.1.30 SUBSYSTEM: Alternate Carbon Metabolism Equation: [c] : atp + glyc --> adp + glyc3p + h Confidence Level: 2 genes: LOCUS:BLBBGE_459#ABBREVIATION:glpK#ECNUMBERS:2.7.1.30# proteins: NAME:glycerol kinase#ABBREVIATION:GlpK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_459)
reactant: 706715
name: glycerol kinase
kinetic law: 706763
reactant: 706703

718142
stoichiometry: 1.0
species: 302514
type: SpeciesReference

305231
value: 0.0
type: LocalParameter

302920
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Succinate semialdehyde-thiamin diphosphate anion_C16H21N4O10P2S
type: Species

708880
stoichiometry: 1.0
species: 302411
type: SpeciesReference

699851
stoichiometry: 1.0
species: 302531
type: SpeciesReference

715357
stoichiometry: 1.0
species: 302459
type: SpeciesReference

706196
stoichiometry: 1.0
species: 302633
type: SpeciesReference

303646
fast: false
type: Reaction
product: 714457
product: 714421
reactant: 714383
kinetic law: 714469
reactant: 714371
product: 714445
name: Pyridoxine 5'-phosphate synthase
product: 714433
product: 714396
reversible: false
notes: Abbreviation: R_PDX5PS Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : dxyl5p + nad + phthr --> co2 + h + (2) h2o + nadh + pdx5p + pi Confidence Level: 2 JLR- two reactions combined (intermediate of the first is unknown) genes: LOCUS:BLBBGE_075#ABBREVIATION:pdxA#ECNUMBERS:1.1.1.262# LOCUS:BLBBGE_015#ABBREVIATION:pdxJ# proteins: NAME:Pyridoxine 5-phosphate biosynthetic protein#ABBREVIATION:PdxAJ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_015 and BLBBGE_075)
product: 714408
reactant: 714359

303787
type: Reaction
fast: false
reactant: 721028
notes: Abbreviation: R_UAGCVT Synonyms: _0 EC Number: 2.5.1.7 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : pep + uacgam --> pi + uaccg Confidence Level: 2 genes: LOCUS:BLBBGE_135#ABBREVIATION:murA#ECNUMBERS:2.5.1.7# proteins: NAME:UDP-N-acetylglucosamine-enolpyruvate transferase#ABBREVIATION:MurA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_135)
reversible: false
reactant: 721040
kinetic law: 721077
product: 721052
name: UDP-N-acetylglucosamine 1-carboxyvinyltransferase
product: 721065

704732
stoichiometry: 1.0
species: 303071
type: SpeciesReference

304111
value: 0.0
type: LocalParameter

303180
kinetic law: 699826
product: 699814
reactant: 699802
notes: Abbreviation: R_CHORM Synonyms: _0 EC Number: 5.4.99.5 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : chor <==> pphn Confidence Level: 2 genes: LOCUS:BLBBGE_341#ABBREVIATION:pheA#ECNUMBERS:5.4.99.5,-!-,4.2.1.51# LOCUS:BLBBGE_343#ABBREVIATION:tyrA#ECNUMBERS:5.4.99.5,-!-,1.3.1.12# LOCUS:BLBBGE_344#ABBREVIATION:aroGpheA#ECNUMBERS:2.5.1.54,-!-,4.2.1.51,-!-,5.4.99.5# proteins: NAME:_bifunctional putative phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase#ABBREVIATION:AroGPheA# NAME:Chorismate mutase T#ABBREVIATION:TyrA# NAME:Chorismate mutase P#ABBREVIATION:PheA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_343) or (BLBBGE_341) or (BLBBGE_344)
fast: false
reversible: true
name: chorismate mutase
type: Reaction

302480
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-Acetyl-L-glutamyl 5-phosphate_C7H9NO8P
type: Species

696967
stoichiometry: 1.0
species: 302660
type: SpeciesReference

303220
reactant: 701296
reversible: false
notes: Abbreviation: R_DCYTD Synonyms: _0 EC Number: 3.5.4.14 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dcyt + h + h2o --> duri + nh4 Confidence Level: 2 genes: LOCUS:BLBBGE_495#ABBREVIATION:cdd#ECNUMBERS:3.5.4.5# proteins: NAME:cytidine/deoxycytidine deaminase#ABBREVIATION:Cdd# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_495)
fast: false
kinetic law: 701344
product: 701320
reactant: 701309
reactant: 701284
product: 701332
name: deoxycytidine deaminase
type: Reaction

304236
value: 0.0
type: LocalParameter

303421
kinetic law: 706691
product: 706679
reactant: 706667
notes: Abbreviation: R_GLYCt Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: glyc[c] <==> glyc[e] Confidence Level: 2 NCD genes: LOCUS:BLBBGE_460#ABBREVIATION:glpF# proteins: NAME:MIP channel, glycerol diffusion#ABBREVIATION:GlpF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_460)
fast: false
reversible: true
name: glycerol transport via channel
type: Reaction

697918
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303707
reactant: 716765
reactant: 716789
fast: false
notes: Abbreviation: R_PTPATi Synonyms: _0 EC Number: 2.7.7.3 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + h + pan4p --> dpcoa + ppi Confidence Level: 2 JLR- irreversible form of PTPAT genes: LOCUS:BLBBGE_286#ABBREVIATION:coaD#ECNUMBERS:2.7.7.3# proteins: NAME:phosphopantetheine adenyltransferase#ABBREVIATION:CoaD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_286)
kinetic law: 716826
name: pantetheine-phosphate adenylyltransferase
reactant: 716777
type: Reaction
reversible: false
product: 716814
product: 716802

303647
fast: false
type: Reaction
reactant: 714493
notes: Abbreviation: R_PERD Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 4per + nad <==> h + nadh + ohpb Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
reversible: true
name: Erythronate 4-phosphate (4per) dehydrogenase
reactant: 714481
product: 714505
product: 714517
kinetic law: 714541
product: 714529

304447
value: 0.0
type: LocalParameter

721282
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305719
value: 999999.0
type: LocalParameter

707401
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303788
kinetic law: 721149
type: Reaction
reversible: false
product: 721125
product: 721137
name: UDP-N-acetylglucosamine diphosphorylase
reactant: 721101
reactant: 721113
fast: false
reactant: 721089
notes: Abbreviation: R_UAGDP Synonyms: _0 EC Number: 2.7.7.23 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : acgam1p + h + utp --> ppi + uacgam Confidence Level: 2 genes: LOCUS:BLBBGE_605#ABBREVIATION:galU#ECNUMBERS:2.7.7.23# proteins: NAME:UTP-glucose-1-phosphate uridylyltransferase#ABBREVIATION:galU# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_605)

716249
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303932
value: 999999.0
type: LocalParameter

708941
stoichiometry: 1.0
species: 302724
type: SpeciesReference

703014
stoichiometry: 1.0
species: 302536
type: SpeciesReference

716959
stoichiometry: 1.0
species: 302650
type: SpeciesReference

713153
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304233
value: 0.0
type: LocalParameter

303706
kinetic law: 716753
product: 716717
name: Phosphatidylserine syntase
reactant: 716693
reversible: false
reactant: 716705
product: 716741
notes: Abbreviation: R_PSSA_Bge Synonyms: _0 EC Number: 2.7.8.8 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : (0.02) cdpdag_Bge + ser-L --> cmp + h + (0.02) ps_Bge Confidence Level: 2 tv genes: LOCUS:BLBBGE_532#ABBREVIATION:pssA#ECNUMBERS:2.7.8.8# proteins: NAME:Phosphatidylserine synthase#ABBREVIATION:PssA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_532)
fast: false
type: Reaction
product: 716729

694996
stoichiometry: 1.0
species: 302538
type: SpeciesReference

304448
value: 0.0
type: LocalParameter

303933
value: 0.0
type: LocalParameter

303789
name: UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
fast: false
reactant: 721161
product: 721197
product: 721209
kinetic law: 721221
product: 721185
reversible: false
notes: Abbreviation: R_UAGPT3 Synonyms: _0 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : uacgam + uagmda --> h + uaagmda + udp Confidence Level: 2 No exact EC number yet: EC 2.4.1.- catalyzed by murG gene in Bacillus subtilis Also found in H. pylori. Ref: Mendz pg 161 (tv) genes: LOCUS:BLBBGE_386#ABBREVIATION:murG#ECNUMBERS:2.4.1.227# proteins: NAME:N-acetylglucosamine transferase#ABBREVIATION:MurG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_386)
reactant: 721173
type: Reaction

708275
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305658
value: 0.0
type: LocalParameter

717625
stoichiometry: 1.0
species: 302552
type: SpeciesReference

721343
stoichiometry: 1.0
species: 302526
type: SpeciesReference

718745
stoichiometry: 1.0
species: 302659
type: SpeciesReference

720907
stoichiometry: 1.0
species: 302493
type: SpeciesReference

699151
stoichiometry: 1.0
species: 302489
type: SpeciesReference

302482
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-Acetyl-L-glutamate 5-semialdehyde_C7H10NO4
type: Species

705154
stoichiometry: 1.0
species: 302526
type: SpeciesReference

706630
stoichiometry: 1.0
species: 302645
type: SpeciesReference

699211
stoichiometry: 5.0
species: 302536
type: SpeciesReference

712560
stoichiometry: 1.0
species: 302853
type: SpeciesReference

305230
value: 0.0
type: LocalParameter

699091
stoichiometry: 5.0
species: 302536
type: SpeciesReference

302923
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: o-Succinylbenzoate_C11H8O5
type: Species

705691
stoichiometry: 1.0
species: 302409
type: SpeciesReference

304951
value: 999999.0
type: LocalParameter

304234
value: 0.0
type: LocalParameter

698619
stoichiometry: 0.001935
species: 302759
type: SpeciesReference

303212
kinetic law: 701066
product: 701054
reactant: 701042
notes: Abbreviation: R_DAPE Synonyms: _0 EC Number: 5.1.1.7 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : 26dap-LL <==> 26dap-M Confidence Level: 2 genes: LOCUS:BLBBGE_397#ABBREVIATION:dapF#ECNUMBERS:5.1.1.7# proteins: NAME:Diaminopimelate epimerase#ABBREVIATION:DapF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_397)
fast: false
reversible: true
name: diaminopimelate epimerase
type: Reaction

713660
stoichiometry: 1.0
species: 302430
type: SpeciesReference

719799
stoichiometry: 1.0
species: 302940
type: SpeciesReference

304450
value: 999999.0
type: LocalParameter

700271
stoichiometry: 1.0
species: 302543
type: SpeciesReference

302472
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _Mevalonate-5-phosphate_C6H10O7P
type: Species

697701
stoichiometry: 1.0
species: 302522
type: SpeciesReference

720439
stoichiometry: 1.0
species: 302638
type: SpeciesReference

305660
value: 999999.0
type: LocalParameter

720330
stoichiometry: 1.0
species: 302620
type: SpeciesReference

717877
stoichiometry: 1.0
species: 302528
type: SpeciesReference

304228
value: 999999.0
type: LocalParameter

714829
stoichiometry: 1.0
species: 302764
type: SpeciesReference

703509
stoichiometry: 1.0
species: 302604
type: SpeciesReference

713515
stoichiometry: 1.0
species: 302613
type: SpeciesReference

698257
stoichiometry: 1.0
species: 302655
type: SpeciesReference

703653
stoichiometry: 1.0
species: 302629
type: SpeciesReference

303211
kinetic law: 701030
product: 701018
reversible: false
name: diaminopimelate decarboxylase
reactant: 700982
type: Reaction
notes: Abbreviation: R_DAPDC Synonyms: _0 EC Number: 4.1.1.20 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : 26dap-M + h --> co2 + lys-L Confidence Level: 2 genes: LOCUS:BLBBGE_331#ABBREVIATION:lysA#ECNUMBERS:4.1.1.20# proteins: NAME:Diaminopimelate decarboxylase#ABBREVIATION:LysA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_331)
reactant: 700994
product: 701006
fast: false

710261
stoichiometry: 1.0
species: 302407
type: SpeciesReference

303850
value: 0.0
type: LocalParameter

694912
stoichiometry: 1.0
species: 302526
type: SpeciesReference

305717
value: 0.0
type: LocalParameter

718395
stoichiometry: 1.0
species: 302479
type: SpeciesReference

716465
stoichiometry: 1.0
species: 302909
type: SpeciesReference

717212
stoichiometry: 1.0
species: 302999
type: SpeciesReference

717297
stoichiometry: 1.0
species: 302654
type: SpeciesReference

700403
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304227
value: -999999.0
type: LocalParameter

711213
stoichiometry: 1.0
species: 302713
type: SpeciesReference

302474
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _6-hydroxymethyl-dihydropterin pyrophosphate_C7H8N5O8P2
type: Species

701368
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305714
value: 0.0
type: LocalParameter

302697
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Malonyl-[acyl-carrier protein]_C14H22N2O10PRS
type: Species

702422
stoichiometry: 1.0
species: 302574
type: SpeciesReference

304226
value: 0.0
type: LocalParameter

700535
stoichiometry: 2.5
species: 302660
type: SpeciesReference

304225
value: 0.0
type: LocalParameter

695104
stoichiometry: 1.0
species: 302659
type: SpeciesReference

721829
stoichiometry: 1.0
species: 302975
type: SpeciesReference

712885
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302473
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _6-hydroxymethyl dihydropterin_C7H9N5O2
type: Species

701296
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302698
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Malate_C4H4O5
type: Species

717140
stoichiometry: 1.0
species: 302576
type: SpeciesReference

706268
stoichiometry: 1.0
species: 302725
type: SpeciesReference

305715
value: 0.0
type: LocalParameter

304108
value: 0.0
type: LocalParameter

710550
stoichiometry: 1.0
species: 302719
type: SpeciesReference

714323
stoichiometry: 1.0
species: 302654
type: SpeciesReference

717080
stoichiometry: 1.0
species: 302686
type: SpeciesReference

305664
value: 999999.0
type: LocalParameter

713720
stoichiometry: 1.0
species: 302659
type: SpeciesReference

704961
stoichiometry: 1.0
species: 302566
type: SpeciesReference

304454
value: 999999.0
type: LocalParameter

305450
value: 999999.0
type: LocalParameter

719702
stoichiometry: 1.0
species: 302935
type: SpeciesReference

305516
value: 0.0
type: LocalParameter

719593
stoichiometry: 1.0
species: 302538
type: SpeciesReference

303216
fast: false
product: 701162
notes: Abbreviation: R_DB4PS Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : ru5p-D --> db4p + for + h Confidence Level: 2 No EC number: ribA in B. subtilis catalyzes two reactions (GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase) genes: LOCUS:BLBBGE_323#ABBREVIATION:ribBA#ECNUMBERS:3.5.4.25,-!-,4.1.99.12# proteins: NAME:_bifunctional 3,4 dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II#ABBREVIATION:RibBA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_323)
kinetic law: 701199
type: Reaction
product: 701187
product: 701175
reversible: false
name: _3,4-Dihydroxy-2-butanone-4-phosphate synthase
reactant: 701150

304957
value: 0.0
type: LocalParameter

714769
stoichiometry: 1.0
species: 302765
type: SpeciesReference

717589
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303853
value: 0.0
type: LocalParameter

305712
value: 0.0
type: LocalParameter

719448
stoichiometry: 5.0
species: 302659
type: SpeciesReference

710314
stoichiometry: 1.0
species: 302659
type: SpeciesReference

707982
stoichiometry: 1.0
species: 302536
type: SpeciesReference

305663
value: -999999.0
type: LocalParameter

705799
stoichiometry: 1.0
species: 302720
type: SpeciesReference

302475
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Acetate_C2H3O2
type: Species

721404
stoichiometry: 1.0
species: 302968
type: SpeciesReference

304453
value: -999999.0
type: LocalParameter

706413
stoichiometry: 1.0
species: 302634
type: SpeciesReference

699632
stoichiometry: 2.0
species: 302654
type: SpeciesReference

304956
value: 0.0
type: LocalParameter

721113
stoichiometry: 1.0
species: 302990
type: SpeciesReference

303215
kinetic law: 701138
type: Reaction
reactant: 701102
fast: false
product: 701126
product: 701114
reactant: 701078
reactant: 701090
notes: Abbreviation: R_DASYN_Bge Synonyms: _0 EC Number: 2.7.7.41 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : ctp + h + (0.02) pa_Bge --> (0.02) cdpdag_Bge + ppi Confidence Level: 2 tv genes: LOCUS:BLBBGE_224#ABBREVIATION:cdsA#ECNUMBERS:2.7.7.41# proteins: NAME:CDP-diglyceride synthetase#ABBREVIATION:CdsA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_224)
name: CDP-Diacylglycerol synthetase
reversible: false

709959
stoichiometry: 1.0
species: 302493
type: SpeciesReference

714191
stoichiometry: 0.02
species: 302749
type: SpeciesReference

303854
value: 0.0
type: LocalParameter

304106
value: 0.0
type: LocalParameter

305713
value: 999999.0
type: LocalParameter

305662
value: 0.0
type: LocalParameter

303851
value: -999999.0
type: LocalParameter

302919
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Sulfate_O4S
type: Species

305710
value: 0.0
type: LocalParameter

705372
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304452
value: 0.0
type: LocalParameter

700499
stoichiometry: 2.5
species: 302659
type: SpeciesReference

696601
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304959
value: 999999.0
type: LocalParameter

701902
stoichiometry: 1.0
species: 302739
type: SpeciesReference

305518
value: 0.0
type: LocalParameter

712825
stoichiometry: 1.0
species: 302865
type: SpeciesReference

304105
value: 0.0
type: LocalParameter

302478
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Acetyl-ACP_C13H23N2O8PRS
type: Species

721683
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304104
value: 999999.0
type: LocalParameter

302918
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Sulfate_O4S
type: Species

305661
value: 0.0
type: LocalParameter

721137
stoichiometry: 1.0
species: 302964
type: SpeciesReference

722239
stoichiometry: 1.0
species: 302500
type: SpeciesReference

711299
stoichiometry: 1.0
species: 302651
type: SpeciesReference

304451
value: 0.0
type: LocalParameter

302629
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Glutamine_C5H10N2O3
type: Species

715600
stoichiometry: 1.0
species: 302864
type: SpeciesReference

304958
value: -999999.0
type: LocalParameter

714227
stoichiometry: 1.0
species: 302719
type: SpeciesReference

304229
value: 0.0
type: LocalParameter

718517
stoichiometry: 1.0
species: 302468
type: SpeciesReference

305711
value: 0.0
type: LocalParameter

303852
value: 999999.0
type: LocalParameter

706316
stoichiometry: 1.0
species: 302880
type: SpeciesReference

302477
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Acetate_C2H3O2
type: Species

714083
stoichiometry: 1.0
species: 302948
type: SpeciesReference

712777
stoichiometry: 1.0
species: 302651
type: SpeciesReference

302546
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Cytidine_C9H13N3O5
type: Species

303578
reversible: false
name: _5'-nucleotidase (XMP)
reactant: 712109
reactant: 712097
type: Reaction
kinetic law: 712145
product: 712133
product: 712121
fast: false
notes: Abbreviation: R_NTD10 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : h2o + xmp --> pi + xtsn Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:

302628
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Glutamine_C5H10N2O3
type: Species

698143
stoichiometry: 1.0
species: 302880
type: SpeciesReference

721937
stoichiometry: 1.0
species: 302536
type: SpeciesReference

304676
value: 0.0
type: LocalParameter

305454
value: 999999.0
type: LocalParameter

304563
value: 0.0
type: LocalParameter

305512
value: 0.0
type: LocalParameter

705580
stoichiometry: 1.0
species: 302538
type: SpeciesReference

705630
stoichiometry: 1.0
species: 302710
type: SpeciesReference

697238
stoichiometry: 1.0
species: 302865
type: SpeciesReference

305381
value: 999999.0
type: LocalParameter

302691
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: potassium_K
type: Species

302547
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Deoxyadenosine_C10H13N5O3
type: Species

707340
stoichiometry: 1.0
species: 302493
type: SpeciesReference

302479
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Acetyl-CoA_C23H34N7O17P3S
type: Species

702397
stoichiometry: 1.0
species: 302865
type: SpeciesReference

303579
reactant: 712169
product: 712193
reactant: 712157
name: _5'-nucleotidase (IMP)
notes: Abbreviation: R_NTD11 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : h2o + imp --> ins + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
type: Reaction
kinetic law: 712205
product: 712181
reversible: false

305513
value: 0.0
type: LocalParameter

304675
value: 0.0
type: LocalParameter

304562
value: 999999.0
type: LocalParameter

699523
stoichiometry: 22.0
species: 302659
type: SpeciesReference

305453
value: -999999.0
type: LocalParameter

720017
stoichiometry: 1.0
species: 302597
type: SpeciesReference

710044
stoichiometry: 1.0
species: 302702
type: SpeciesReference

302692
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Leucine_C6H13NO2
type: Species

707629
stoichiometry: 1.0
species: 302474
type: SpeciesReference

708444
stoichiometry: 1.0
species: 302683
type: SpeciesReference

302544
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Cystathionine_C7H14N2O4S
type: Species

712934
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302626
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: GDP_C10H12N5O11P2
type: Species

305514
value: 999999.0
type: LocalParameter

700800
stoichiometry: 1.0
species: 302556
type: SpeciesReference

304339
value: 0.0
type: LocalParameter

305452
value: 0.0
type: LocalParameter

304561
value: -999999.0
type: LocalParameter

706521
stoichiometry: 1.0
species: 302719
type: SpeciesReference

304674
value: 0.0
type: LocalParameter

705263
stoichiometry: 1.0
species: 302705
type: SpeciesReference

702518
stoichiometry: 1.0
species: 302659
type: SpeciesReference

717769
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302625
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Glycolaldehyde_C2H4O2
type: Species

305515
value: 0.0
type: LocalParameter

717431
stoichiometry: 1.0
species: 302889
type: SpeciesReference

303217
reactant: 701236
reactant: 701212
type: Reaction
fast: false
notes: Abbreviation: R_DCMPDA Synonyms: _1 EC Number: 3.5.4.12 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dcmp + h + h2o <==> dump + nh4 Confidence Level: 2 genes: LOCUS:BLBBGE_505#ABBREVIATION:comEB#ECNUMBERS:3.5.4.12# proteins: NAME:dCMP deaminase#ABBREVIATION:ComEB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_505)
reactant: 701224
product: 701248
name: _dCMP deaminase
product: 701260
kinetic law: 701272
reversible: true

709800
stoichiometry: 1.0
species: 302659
type: SpeciesReference

715687
stoichiometry: 1.0
species: 302763
type: SpeciesReference

304338
value: 999999.0
type: LocalParameter

305229
value: 999999.0
type: LocalParameter

305301
value: 0.0
type: LocalParameter

304560
value: 0.0
type: LocalParameter

305451
value: 0.0
type: LocalParameter

711068
stoichiometry: 1.0
species: 302865
type: SpeciesReference

304673
value: 999999.0
type: LocalParameter

698727
stoichiometry: 0.241
species: 302940
type: SpeciesReference

703581
stoichiometry: 1.0
species: 302616
type: SpeciesReference

702663
stoichiometry: 1.0
species: 302536
type: SpeciesReference

716573
stoichiometry: 1.0
species: 302447
type: SpeciesReference

304337
value: 0.0
type: LocalParameter

709279
stoichiometry: 1.0
species: 302526
type: SpeciesReference

303369
kinetic law: 704985
product: 704973
product: 704961
reactant: 704949
notes: Abbreviation: R_FBAb Synonyms: _0 EC Number: 4.1.2.13 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : f1p <==> dhap + glyald Confidence Level: 2 genes: LOCUS:BLBBGE_476#ABBREVIATION:fbaA#ECNUMBERS:4.1.2.13# proteins: NAME:fructose-bisphosphate aldolase II#ABBREVIATION:FbaA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_476)
fast: false
reversible: true
name: fructose-bisphosphate aldolaseB
type: Reaction

718456
stoichiometry: 1.0
species: 302714
type: SpeciesReference

305458
value: -999999.0
type: LocalParameter

302624
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N1-(5-Phospho-D-ribosyl)glycinamide_C7H14N2O8P
type: Species

694802
stoichiometry: 1.0
species: 302479
type: SpeciesReference

699439
stoichiometry: 6.0
species: 302487
type: SpeciesReference

716417
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302542
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Cysteine_C3H7NO2S
type: Species

697798
stoichiometry: 1.0
species: 302455
type: SpeciesReference

303574
kinetic law: 712023
product: 712011
product: 711999
reactant: 711987
notes: Abbreviation: R_NPHS Synonyms: _0 EC Number: 4.1.3.36 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : sbzcoa --> coa + dhna Confidence Level: 2 genes: LOCUS:BLBBGE_267#ABBREVIATION:menB#ECNUMBERS:4.1.3.36# proteins: NAME:Napthoate synthase#ABBREVIATION:MenB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_267)
fast: false
reversible: false
name: naphthoate synthase
type: Reaction

711105
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304336
value: 0.0
type: LocalParameter

304679
value: 0.0
type: LocalParameter

720222
stoichiometry: 1.0
species: 302425
type: SpeciesReference

302543
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Cysteine_C3H7NO2S
type: Species

701042
stoichiometry: 1.0
species: 302416
type: SpeciesReference

705859
stoichiometry: 1.0
species: 302659
type: SpeciesReference

721791
stoichiometry: 1.0
species: 302526
type: SpeciesReference

710996
stoichiometry: 1.0
species: 302526
type: SpeciesReference

302696
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Lysine_C6H15N2O2
type: Species

701587
stoichiometry: 1.0
species: 302410
type: SpeciesReference

699959
stoichiometry: 1.0
species: 302536
type: SpeciesReference

303575
type: Reaction
reactant: 712048
reactant: 712035
fast: false
product: 712060
name: _5'-nucleotidase (dUMP)
reversible: false
kinetic law: 712085
notes: Abbreviation: R_NTD1 Synonyms: _0 EC Number: 3.1.3.5 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dump + h2o --> duri + pi Confidence Level: 1 Wide specificity for 5'-nucleotides Also see EC 3.1.3.31 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 712073

709050
stoichiometry: 1.0
species: 302536
type: SpeciesReference

700897
stoichiometry: 1.0
species: 302725
type: SpeciesReference

304678
value: 0.0
type: LocalParameter

702313
stoichiometry: 1.0
species: 302421
type: SpeciesReference

705979
stoichiometry: 1.0
species: 302597
type: SpeciesReference

709339
stoichiometry: 1.0
species: 302660
type: SpeciesReference

302622
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Glucosamine 6-phosphate_C6H13NO8P
type: Species

712291
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302693
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Leucine_C6H13NO2
type: Species

713006
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304099
value: -999999.0
type: LocalParameter

304335
value: 0.0
type: LocalParameter

305510
value: 999999.0
type: LocalParameter

305456
value: 0.0
type: LocalParameter

304677
value: 999999.0
type: LocalParameter

304739
value: 0.0
type: LocalParameter

302621
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Glucosamine 1-phosphate_C6H13NO8P
type: Species

720547
stoichiometry: 1.0
species: 302950
type: SpeciesReference

711397
stoichiometry: 1.0
species: 302528
type: SpeciesReference

302541
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: CTP_C9H12N3O14P3
type: Species

302694
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Lysine_C6H15N2O2
type: Species

304334
value: 0.0
type: LocalParameter

305511
value: 0.0
type: LocalParameter

720763
stoichiometry: 1.0
species: 302955
type: SpeciesReference

305455
value: 0.0
type: LocalParameter

303366
kinetic law: 704937
product: 704925
product: 704913
reactant: 704901
notes: Abbreviation: R_FBAa Synonyms: _0 EC Number: 4.1.2.13 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : fdp <==> dhap + g3p Confidence Level: 2 genes: LOCUS:BLBBGE_476#ABBREVIATION:fbaA#ECNUMBERS:4.1.2.13# proteins: NAME:fructose-bisphosphate aldolase II#ABBREVIATION:FbaA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_476)
fast: false
reversible: true
name: fructose-bisphosphate aldolaseA
type: Reaction

713830
stoichiometry: 1.0
species: 302748
type: SpeciesReference

703159
stoichiometry: 1.0
species: 302760
type: SpeciesReference

303062
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Pyruvate_C3H3O3
type: Species

303796
reactant: 721573
name: Undecaprenyl diphosphate synthase
reactant: 721585
kinetic law: 721621
reversible: false
fast: false
product: 721609
type: Reaction
product: 721597
notes: Abbreviation: R_UDCPDPS Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : frdp + (8) ipdp --> (8) ppi + udcpdp Confidence Level: 2 tv genes: LOCUS:BLBBGE_087#ABBREVIATION:ispU#ECNUMBERS:2.5.1.31# proteins: NAME:Undecaprenyl diphosphate synthase#ABBREVIATION:UppS# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_087)

703958
stoichiometry: 1.0
species: 303036
type: SpeciesReference

714685
stoichiometry: 1.0
species: 302408
type: SpeciesReference

715778
stoichiometry: 1.0
species: 302624
type: SpeciesReference

302719
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2
type: Species

711939
stoichiometry: 1.0
species: 302729
type: SpeciesReference

303386
fast: false
notes: Abbreviation: R_FUMt2_2 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: fum[e] + (2) h[e] --> fum[c] + (2) h[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_358#ABBREVIATION:dctA# proteins: NAME:C4-dicarboxylate transporter#ABBREVIATION:DctA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_358)
reactant: 705481
reversible: false
type: Reaction
kinetic law: 705530
reactant: 705493
name: Fumarate transport via proton symport (2 H)
product: 705505
product: 705518

304544
value: 999999.0
type: LocalParameter

302930
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)_C25H45N2O8PRS
type: Species

305435
value: 999999.0
type: LocalParameter

305374
value: 0.0
type: LocalParameter

305221
value: 999999.0
type: LocalParameter

304330
value: 0.0
type: LocalParameter

304084
value: 0.0
type: LocalParameter

304606
value: 0.0
type: LocalParameter

304723
value: 999999.0
type: LocalParameter

716741
stoichiometry: 0.02
species: 302883
type: SpeciesReference

303924
value: 0.0
type: LocalParameter

697090
stoichiometry: 1.0
species: 302889
type: SpeciesReference

303715
product: 717176
type: Reaction
product: 717164
name: purine-nucleoside phosphorylase (Deoxyinosine)
kinetic law: 717188
reversible: true
reactant: 717152
fast: false
reactant: 717140
notes: Abbreviation: R_PUNP6 Synonyms: _0 EC Number: 2.4.2.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : din + pi <==> 2dr1p + hxan Confidence Level: 2 Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase genes: LOCUS:BLBBGE_377#ABBREVIATION:pndA#ECNUMBERS:2.4.2.1# proteins: NAME:purine-nucleoside phosphorylase#ABBREVIATION:PndA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)

703219
stoichiometry: 1.0
species: 302502
type: SpeciesReference

696492
stoichiometry: 1.0
species: 302407
type: SpeciesReference

715923
stoichiometry: 1.0
species: 302853
type: SpeciesReference

694778
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304012
value: 999999.0
type: LocalParameter

303061
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Proline_C5H9NO2
type: Species

714613
stoichiometry: 1.0
species: 302447
type: SpeciesReference

705033
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304690
value: 0.0
type: LocalParameter

697446
stoichiometry: 1.0
species: 302526
type: SpeciesReference

302718
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Nicotinate_C6H4NO2
type: Species

305222
value: 0.0
type: LocalParameter

305375
value: 999999.0
type: LocalParameter

710404
stoichiometry: 1.0
species: 302470
type: SpeciesReference

714973
stoichiometry: 1.0
species: 302853
type: SpeciesReference

707920
stoichiometry: 1.0
species: 302668
type: SpeciesReference

304083
value: 0.0
type: LocalParameter

304605
value: 999999.0
type: LocalParameter

304722
value: 0.0
type: LocalParameter

305436
value: 0.0
type: LocalParameter

304545
value: 0.0
type: LocalParameter

712608
stoichiometry: 1.0
species: 302564
type: SpeciesReference

305020
value: 0.0
type: LocalParameter

303797
reactant: 721634
name: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase
kinetic law: 721719
type: Reaction
fast: false
reversible: false
product: 721695
product: 721671
reactant: 721659
reactant: 721647
product: 721707
product: 721683
notes: Abbreviation: R_UGMDDS Synonyms: _0 EC Number: 6.3.2.15 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : alaala + atp + ugmd --> adp + h + pi + ugmda Confidence Level: 2 genes: LOCUS:BLBBGE_100#ABBREVIATION:murF#ECNUMBERS:6.3.2.10# proteins: NAME:D-alanine:D-alanine-adding enzme#ABBREVIATION:MurF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_100)

709666
stoichiometry: 1.0
species: 302700
type: SpeciesReference

303714
type: Reaction
reactant: 717092
fast: false
notes: Abbreviation: R_PUNP5 Synonyms: _0 EC Number: 2.4.2.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : ins + pi <==> hxan + r1p Confidence Level: 2 Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase genes: LOCUS:BLBBGE_377#ABBREVIATION:pndA#ECNUMBERS:2.4.2.1# proteins: NAME:purine-nucleoside phosphorylase#ABBREVIATION:PndA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)
reversible: true
product: 717116
name: purine-nucleoside phosphorylase (Inosine)
product: 717104
kinetic law: 717128
reactant: 717080

304013
value: 0.0
type: LocalParameter

303794
product: 721524
notes: Abbreviation: R_UDCPDP Synonyms: _0 EC Number: 3.6.1.27 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : h2o + udcpdp --> h + pi + udcpp Confidence Level: 2 genes: LOCUS:BLBBGE_362#ABBREVIATION:uppP#ECNUMBERS:3.6.1.27# proteins: NAME:undecaprenyl-diphosphatase#ABBREVIATION:UppP# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_362)
reversible: false
reactant: 721500
fast: false
kinetic law: 721560
reactant: 721512
product: 721536
product: 721548
name: undecaprenyl-diphosphatase
type: Reaction

304086
value: 0.0
type: LocalParameter

303060
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Porphobilinogen_C10H13N2O4
type: Species

699295
stoichiometry: 6.0
species: 302697
type: SpeciesReference

305223
value: 0.0
type: LocalParameter

304332
value: 0.0
type: LocalParameter

304870
value: 0.0
type: LocalParameter

304691
value: 0.0
type: LocalParameter

305376
value: 0.0
type: LocalParameter

700115
stoichiometry: 1.0
species: 302984
type: SpeciesReference

303571
reactant: 711939
type: Reaction
reactant: 711915
reactant: 711927
notes: Abbreviation: R_NNAT Synonyms: _0 EC Number: 2.7.7.18 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + h + nicrnt --> dnad + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_327#ABBREVIATION:nadD#ECNUMBERS:2.7.7.18# proteins: NAME:Nicotinic acid mononucleotide adenyltransferase#ABBREVIATION:NadD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_327)
kinetic law: 711975
reversible: false
product: 711963
name: nicotinate-nucleotide adenylyltransferase
product: 711951
fast: false

303926
value: -999999.0
type: LocalParameter

304546
value: 0.0
type: LocalParameter

712716
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305437
value: 0.0
type: LocalParameter

303414
kinetic law: 706497
product: 706485
reactant: 706473
notes: Abbreviation: R_GLYALDt Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: glyald[e] <==> glyald[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_460#ABBREVIATION:glpF# proteins: NAME:MIP channel, glycerol diffusion#ABBREVIATION:GlpF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_460)
fast: false
reversible: true
name: Glyceraldehyde facilitated diffusion
type: Reaction

303717
product: 717297
reactant: 717285
kinetic law: 717334
name: pyridoxamine 5'-phosphate oxidase
product: 717309
fast: false
reactant: 717273
product: 717321
reversible: false
notes: Abbreviation: R_PYAM5PO Synonyms: _0 EC Number: 1.4.3.5 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : h2o + o2 + pyam5p --> h2o2 + nh4 + pydx5p Confidence Level: 2 NCD genes: LOCUS:BLBBGE_050#ABBREVIATION:pdxH#ECNUMBERS:1.4.3.5# proteins: NAME:Pyridoxine 5-phosphate oxidase#ABBREVIATION:PdxH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_050)
reactant: 717261
type: Reaction

304725
value: 0.0
type: LocalParameter

304608
value: 0.0
type: LocalParameter

707701
stoichiometry: 1.0
species: 302724
type: SpeciesReference

704528
stoichiometry: 1.0
species: 302894
type: SpeciesReference

705907
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305021
value: 999999.0
type: LocalParameter

708395
stoichiometry: 1.0
species: 302633
type: SpeciesReference

304014
value: 0.0
type: LocalParameter

304692
value: -999999.0
type: LocalParameter

722070
stoichiometry: 1.0
species: 302651
type: SpeciesReference

721707
stoichiometry: 1.0
species: 302979
type: SpeciesReference

305377
value: 0.0
type: LocalParameter

703363
stoichiometry: 1.0
species: 302523
type: SpeciesReference

305224
value: 0.0
type: LocalParameter

303389
product: 705580
product: 705593
reactant: 705542
reactant: 705554
fast: false
kinetic law: 705605
name: glucosamine-1-phosphate N-acetyltransferase
notes: Abbreviation: R_G1PACT Synonyms: _0 EC Number: 2.3.1.157 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : accoa + gam1p --> acgam1p + coa + h Confidence Level: 2 genes: LOCUS:BLBBGE_605#ABBREVIATION:galU#ECNUMBERS:2.7.7.23# proteins: NAME:UTP-glucose-1-phosphate uridylyltransferase#ABBREVIATION:galU# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_605)
reversible: false
product: 705567
type: Reaction

303570
reactant: 711855
reactant: 711843
notes: Abbreviation: R_NMNAT Synonyms: _0 EC Number: 2.7.7.1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + h + nmn --> nad + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_327#ABBREVIATION:nadD#ECNUMBERS:2.7.7.18# proteins: NAME:Nicotinic acid mononucleotide adenyltransferase#ABBREVIATION:NadD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_327)
fast: false
reversible: false
product: 711891
product: 711879
kinetic law: 711903
name: nicotinamide-nucleotide adenylyltransferase
reactant: 711867
type: Reaction

303413
kinetic law: 706461
fast: false
reactant: 706413
reversible: false
notes: Abbreviation: R_GLUt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: glu-L[e] + h[e] --> glu-L[c] + h[c] Confidence Level: 2 NCD genes: LOCUS:BLBBGE_358#ABBREVIATION:gltP# proteins: NAME:DAACS, glutamate or aspartate symport#ABBREVIATION:GltP# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_358)
reactant: 706425
product: 706449
product: 706437
type: Reaction
name: L-glutamate transport via proton symport

304724
value: 0.0
type: LocalParameter

699730
stoichiometry: 2.0
species: 302493
type: SpeciesReference

304547
value: 0.0
type: LocalParameter

302890
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Pyridoxal_C8H9NO3
type: Species

715478
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304607
value: 0.0
type: LocalParameter

702747
stoichiometry: 1.0
species: 302583
type: SpeciesReference

303716
fast: false
product: 717236
kinetic law: 717249
reversible: true
name: purine-nucleoside phosphorylase (Xanthosine)
product: 717224
reactant: 717200
type: Reaction
notes: Abbreviation: R_PUNP7 Synonyms: _0 EC Number: 2.4.2.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : pi + xtsn <==> r1p + xan Confidence Level: 2 Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferasextsn genes: LOCUS:BLBBGE_377#ABBREVIATION:pndA#ECNUMBERS:2.4.2.1# proteins: NAME:purine-nucleoside phosphorylase#ABBREVIATION:PndA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)
reactant: 717212

305022
value: 0.0
type: LocalParameter

695795
stoichiometry: 1.0
species: 302526
type: SpeciesReference

707569
stoichiometry: 1.0
species: 302671
type: SpeciesReference

703099
stoichiometry: 2.0
species: 302659
type: SpeciesReference

304080
value: 0.0
type: LocalParameter

303382
product: 705384
notes: Abbreviation: R_FTHFCL Synonyms: _0 EC Number: 6.3.3.2 SUBSYSTEM: Cofactor Metabolism Equation: [c] : 5fthf + atp --> adp + methf + pi Confidence Level: 2 NCD genes: LOCUS:BLBBGE_130#ABBREVIATION:ygfA#ECNUMBERS:6.3.3.2# proteins: NAME:5-formyltetrahydrofolate cyclo-ligase#ABBREVIATION:YgfA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_130)
kinetic law: 705421
product: 705397
reactant: 705372
type: Reaction
product: 705409
reversible: false
reactant: 705360
fast: false
name: _5-formethyltetrahydrofolate cyclo-ligase

304693
value: 999999.0
type: LocalParameter

304540
value: 999999.0
type: LocalParameter

303066
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Sulfate_O4S
type: Species

305225
value: 999999.0
type: LocalParameter

303792
fast: false
reactant: 721343
kinetic law: 721416
name: UDP-N-acetylmuramoyl-L-alanine synthetase
reactant: 721355
product: 721368
product: 721404
reversible: false
reactant: 721331
type: Reaction
notes: Abbreviation: R_UAMAS Synonyms: _0 EC Number: 6.3.2.8 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : ala-L + atp + uamr --> adp + h + pi + uama Confidence Level: 2 genes: LOCUS:BLBBGE_385#ABBREVIATION:murC#ECNUMBERS:6.3.2.8# proteins: NAME:UDP-N-acetylmuramate-alanine ligase#ABBREVIATION:MurC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_385)
product: 721380
product: 721392

712060
stoichiometry: 1.0
species: 302589
type: SpeciesReference

713237
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304015
value: 0.0
type: LocalParameter

704018
stoichiometry: 1.0
species: 302691
type: SpeciesReference

711324
stoichiometry: 1.0
species: 302526
type: SpeciesReference

711771
stoichiometry: 1.0
species: 302493
type: SpeciesReference

305370
value: 0.0
type: LocalParameter

303711
reactant: 716971
type: Reaction
name: purine-nucleoside phosphorylase (Guanosine)
product: 716996
fast: false
reactant: 716959
kinetic law: 717008
notes: Abbreviation: R_PUNP3 Synonyms: _0 EC Number: 2.4.2.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : gsn + pi <==> gua + r1p Confidence Level: 2 Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase genes: LOCUS:BLBBGE_377#ABBREVIATION:pndA#ECNUMBERS:2.4.2.1# proteins: NAME:purine-nucleoside phosphorylase#ABBREVIATION:PndA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)
product: 716983
reversible: true

305023
value: 0.0
type: LocalParameter

709497
stoichiometry: 1.0
species: 302454
type: SpeciesReference

696120
stoichiometry: 1.0
species: 302617
type: SpeciesReference

305439
value: -999999.0
type: LocalParameter

303928
value: 999999.0
type: LocalParameter

302714
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Sodium_Na
type: Species

719290
stoichiometry: 1.0
species: 302928
type: SpeciesReference

710778
stoichiometry: 3.8
species: 302659
type: SpeciesReference

304541
value: 0.0
type: LocalParameter

304871
value: 0.0
type: LocalParameter

305226
value: 0.0
type: LocalParameter

304694
value: 0.0
type: LocalParameter

303793
notes: Abbreviation: R_UAPGR Synonyms: _0 EC Number: 1.1.1.158 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : h + nadph + uaccg --> nadp + uamr Confidence Level: 2 genes: LOCUS:BLBBGE_376#ABBREVIATION:murB#ECNUMBERS:1.1.1.158# proteins: NAME:UDP-N-acetylenolpyruvoylglycosamine reductase#ABBREVIATION:MurB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_376)
reversible: false
fast: false
product: 721464
reactant: 721440
reactant: 721452
name: UDP-N-acetylenolpyruvoylglucosamine reductase
reactant: 721428
product: 721476
kinetic law: 721488
type: Reaction

304016
value: 999999.0
type: LocalParameter

305371
value: 999999.0
type: LocalParameter

303710
reactant: 716910
type: Reaction
kinetic law: 716947
reactant: 716898
name: purine-nucleoside phosphorylase (Deoxyadenosine)
notes: Abbreviation: R_PUNP2 Synonyms: _0 EC Number: 2.4.2.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dad-2 + pi <==> 2dr1p + ade Confidence Level: 2 Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase genes: LOCUS:BLBBGE_377#ABBREVIATION:pndA#ECNUMBERS:2.4.2.1# proteins: NAME:purine-nucleoside phosphorylase#ABBREVIATION:PndA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)
reversible: true
product: 716934
product: 716922
fast: false

305024
value: 0.0
type: LocalParameter

708311
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304609
value: 999999.0
type: LocalParameter

720992
stoichiometry: 1.0
species: 302487
type: SpeciesReference

303929
value: 0.0
type: LocalParameter

708722
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304082
value: 999999.0
type: LocalParameter

303177
reactant: 699718
reactant: 699694
product: 699778
kinetic law: 699790
product: 699754
product: 699730
reactant: 699706
type: Reaction
name: carbamoyl-phosphate synthase (glutamine-hydrolysing)
fast: false
reversible: false
reactant: 699681
product: 699766
product: 699742
notes: Abbreviation: R_CBPS Synonyms: _0 EC Number: 6.3.5.5 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : (2) atp + gln-L + h2o + hco3 --> (2) adp + cbp + glu-L + (2) h + pi Confidence Level: 2 genes: LOCUS:BLBBGE_316#ABBREVIATION:carA#ECNUMBERS:6.3.5.5# LOCUS:BLBBGE_317#ABBREVIATION:carB#ECNUMBERS:6.3.5.5# proteins: NAME:carbamoyl-phosphate synthetase#ABBREVIATION:Car# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_316 and BLBBGE_317)

304542
value: 0.0
type: LocalParameter

304695
value: 0.0
type: LocalParameter

302717
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Nicotinate_C6H4NO2
type: Species

305372
value: 0.0
type: LocalParameter

698065
stoichiometry: 1.0
species: 302500
type: SpeciesReference

717973
stoichiometry: 1.0
species: 302587
type: SpeciesReference

305025
value: 999999.0
type: LocalParameter

304017
value: 0.0
type: LocalParameter

709557
stoichiometry: 1.0
species: 302526
type: SpeciesReference

694876
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304721
value: 0.0
type: LocalParameter

722155
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305227
value: 0.0
type: LocalParameter

303418
reactant: 706605
fast: false
name: glycolate transport via proton symport, reversible
product: 706642
reactant: 706618
notes: Abbreviation: R_GLYCLTt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: glyclt[e] + h[e] <==> glyclt[c] + h[c] Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
reversible: true
type: Reaction
kinetic law: 706654
product: 706630

303385
kinetic law: 705469
product: 705457
reactant: 705445
reactant: 705433
notes: Abbreviation: R_FUM Synonyms: _0 EC Number: 4.2.1.2 SUBSYSTEM: Citric Acid Cycle Equation: [c] : fum + h2o <==> mal-L Confidence Level: 2 genes: LOCUS:BLBBGE_536#ABBREVIATION:fumC#ECNUMBERS:4.2.1.2# proteins: NAME:fumarase C#ABBREVIATION:FumC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_536)
fast: false
reversible: true
name: fumarase
type: Reaction

303176
kinetic law: 699669
product: 699657
product: 699645
reactant: 699632
notes: Abbreviation: R_CAT Synonyms: _4 EC Number: 1.11.1.6 SUBSYSTEM: Unassigned Equation: [c] : (2) h2o2 --> (2) h2o + o2 Confidence Level: 2 JLR genes: LOCUS:BLBBGE_349#ABBREVIATION:ahpC#ECNUMBERS:1.11.1.6# proteins: NAME:peroxiredoxin#ABBREVIATION:ahpC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_349)
fast: false
reversible: false
name: catalase
type: Reaction

303063
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Serine_C3H7NO3
type: Species

305373
value: 0.0
type: LocalParameter

304081
value: 0.0
type: LocalParameter

304873
value: 0.0
type: LocalParameter

304696
value: 0.0
type: LocalParameter

304720
value: 0.0
type: LocalParameter

304543
value: -999999.0
type: LocalParameter

713370
stoichiometry: 1.0
species: 302650
type: SpeciesReference

719896
stoichiometry: 1.0
species: 302853
type: SpeciesReference

697846
stoichiometry: 1.0
species: 302723
type: SpeciesReference

710201
stoichiometry: 1.0
species: 302472
type: SpeciesReference

303791
product: 721269
product: 721294
type: Reaction
notes: Abbreviation: R_UAMAGS Synonyms: _0 EC Number: 6.3.2.9 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : atp + glu-D + uama --> adp + h + pi + uamag Confidence Level: 2 genes: LOCUS:BLBBGE_388#ABBREVIATION:murD#ECNUMBERS:6.3.2.9# proteins: NAME:UDP-N-acetylmuramoylalanine-D-glutamate ligase#ABBREVIATION:MurD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_388)
reversible: false
product: 721307
reactant: 721257
reactant: 721233
fast: false
product: 721282
kinetic law: 721319
name: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
reactant: 721245

305026
value: 0.0
type: LocalParameter

720451
stoichiometry: 1.0
species: 302493
type: SpeciesReference

708200
stoichiometry: 1.0
species: 302659
type: SpeciesReference

707063
stoichiometry: 3.0
species: 302655
type: SpeciesReference

303712
notes: Abbreviation: R_PUNP4 Synonyms: _0 EC Number: 2.4.2.1 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dgsn + pi <==> 2dr1p + gua Confidence Level: 2 Specificity not completely determined. Can also catalyse ribosyltransferase reactions of the type catalysed by EC 2.4.2.5, nucleoside ribosyltransferase genes: LOCUS:BLBBGE_377#ABBREVIATION:pndA#ECNUMBERS:2.4.2.1# proteins: NAME:purine-nucleoside phosphorylase#ABBREVIATION:PndA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)
reactant: 717032
product: 717044
kinetic law: 717068
name: purine-nucleoside phosphorylase (Deoxyguanosine)
reactant: 717020
product: 717056
reversible: true
fast: false
type: Reaction

304018
value: 0.0
type: LocalParameter

718673
stoichiometry: 1.0
species: 302723
type: SpeciesReference

305228
value: 0.0
type: LocalParameter

698353
stoichiometry: 6.0E-6
species: 302538
type: SpeciesReference

303417
product: 706581
kinetic law: 706593
product: 706557
notes: Abbreviation: R_GLYCL Synonyms: _0 SUBSYSTEM: Folate Metabolism Equation: [c] : gly + nad + thf <==> co2 + mlthf + nadh + nh4 Confidence Level: 2 genes: LOCUS:BLBBGE_147#ABBREVIATION:lpd#ECNUMBERS:1.8.1.4# LOCUS:BLBBGE_616#ABBREVIATION:gcvP#ECNUMBERS:1.4.4.2# LOCUS:BLBBGE_418#ABBREVIATION:gcvH# LOCUS:BLBBGE_188#ABBREVIATION:gcvT#ECNUMBERS:2.1.2.10# proteins: NAME:Glycine cleavage complex, T#ABBREVIATION:GcvT# NAME:glycine cleavage complex, H#ABBREVIATION:GcvH# NAME:Glycine cleavage complex, P#ABBREVIATION:GcvP# NAME:dihydrolipoamide dehydrogenase#ABBREVIATION:LpdA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_147) and (BLBBGE_616) and (BLBBGE_188) and (BLBBGE_418)
reactant: 706509
reversible: true
fast: false
reactant: 706533
name: Glycine Cleavage System
product: 706545
type: Reaction
product: 706569
reactant: 706521

721065
stoichiometry: 1.0
species: 302963
type: SpeciesReference

304942
value: 0.0
type: LocalParameter

716056
stoichiometry: 1.0
species: 302659
type: SpeciesReference

698461
stoichiometry: 0.25
species: 302633
type: SpeciesReference

304876
value: 0.0
type: LocalParameter

716116
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305027
value: 0.0
type: LocalParameter

303868
value: 0.0
type: LocalParameter

305665
value: 0.0
type: LocalParameter

302938
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Thiamin_C12H17N4OS
type: Species

304124
value: 0.0
type: LocalParameter

703436
stoichiometry: 1.0
species: 302543
type: SpeciesReference

304431
value: -999999.0
type: LocalParameter

302895
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: alpha-D-Ribose 1-phosphate_C5H9O8P
type: Species

303631
type: Reaction
product: 713866
product: 713854
reactant: 713842
notes: Abbreviation: R_ORPT Synonyms: _0 EC Number: 2.4.2.10 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : orot + prpp --> orot5p + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_512#ABBREVIATION:pyrFE#ECNUMBERS:2.4.2.10# proteins: NAME:Orotidine 5'-phosphate decarboxylase-Orotate phosphoribosyltransferase#ABBREVIATION:PyrFE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_512)
kinetic law: 713878
reactant: 713830
reversible: false
fast: false
name: orotate phosphoribosyltransferase

303175
reactant: 699511
fast: false
product: 699572
reactant: 699536
type: Reaction
kinetic law: 699620
product: 699560
name: Fatty acid biosynthesis (n-C18:1)
reactant: 699523
reversible: false
product: 699608
product: 699596
product: 699584
notes: Abbreviation: R_C181SN Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : actACP + (22) h + (7) malACP + (15) nadph --> (7) ACP + (7) co2 + (8) h2o + (15) nadp + octeACP Confidence Level: 2 tv genes: LOCUS:BLBBGE_037#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-# LOCUS:none#ABBREVIATION:fabA#ECNUMBERS:4.2.1.60# LOCUS:BLBBGE_346#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9# LOCUS:BLBBGE_057#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100# LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.41# LOCUS:BLBBGE_111#ABBREVIATION:fabH#ECNUMBERS:2.3.1.41# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase#ABBREVIATION:FabH# NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabG# NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI# NAME:beta-hydroxydecanoyl thioester dehydrase#ABBREVIATION:FabA# NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_037) and (BLBBGE_079) or (BLBBGE_111) and (BLBBGE_057) and (BLBBGE_346)
reactant: 699548

720883
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304943
value: 0.0
type: LocalParameter

304875
value: 999999.0
type: LocalParameter

702807
stoichiometry: 1.0
species: 302588
type: SpeciesReference

303867
value: 0.0
type: LocalParameter

302939
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Thiamine diphosphate_C12H16N4O7P2S
type: Species

711663
stoichiometry: 1.0
species: 302557
type: SpeciesReference

704126
stoichiometry: 1.0
species: 302700
type: SpeciesReference

305666
value: 0.0
type: LocalParameter

304432
value: 999999.0
type: LocalParameter

302490
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Adenine_C5H5N5
type: Species

714396
stoichiometry: 1.0
species: 302536
type: SpeciesReference

302710
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Menaquinone 8_C51H72O2
type: Species

304878
value: -999999.0
type: LocalParameter

709448
stoichiometry: 1.0
species: 302659
type: SpeciesReference

714179
stoichiometry: 2.0
species: 302487
type: SpeciesReference

698570
stoichiometry: 0.00215
species: 302719
type: SpeciesReference

709971
stoichiometry: 1.0
species: 302659
type: SpeciesReference

716513
stoichiometry: 1.0
species: 302659
type: SpeciesReference

697114
stoichiometry: 1.0
species: 302893
type: SpeciesReference

304126
value: 0.0
type: LocalParameter

704468
stoichiometry: 1.0
species: 303060
type: SpeciesReference

305029
value: 0.0
type: LocalParameter

697652
stoichiometry: 1.0
species: 302518
type: SpeciesReference

711867
stoichiometry: 1.0
species: 302730
type: SpeciesReference

304940
value: -999999.0
type: LocalParameter

713455
stoichiometry: 1.0
species: 302744
type: SpeciesReference

697507
stoichiometry: 1.0
species: 302853
type: SpeciesReference

710622
stoichiometry: 1.0
species: 302710
type: SpeciesReference

304433
value: 0.0
type: LocalParameter

304191
value: 0.0
type: LocalParameter

302713
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Sodium_Na
type: Species

303068
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Thiamin_C12H17N4OS
type: Species

713599
stoichiometry: 1.0
species: 302500
type: SpeciesReference

304877
value: 0.0
type: LocalParameter

304941
value: 999999.0
type: LocalParameter

713708
stoichiometry: 1.0
species: 302437
type: SpeciesReference

305668
value: -999999.0
type: LocalParameter

303869
value: 0.0
type: LocalParameter

303172
reactant: 699415
product: 699451
product: 699487
reversible: false
product: 699439
type: Reaction
product: 699463
kinetic law: 699499
reactant: 699391
name: Fatty acid biosynthesis (n-C16:1)
notes: Abbreviation: R_C161SN Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : actACP + (19) h + (6) malACP + (13) nadph --> (6) ACP + (6) co2 + (7) h2o + hdeACP + (13) nadp Confidence Level: 2 tv genes: LOCUS:BLBBGE_037#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-# LOCUS:none#ABBREVIATION:fabA#ECNUMBERS:4.2.1.60# LOCUS:BLBBGE_346#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9# LOCUS:BLBBGE_057#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100# LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.179# LOCUS:BLBBGE_111#ABBREVIATION:fabH#ECNUMBERS:2.3.1.41# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase#ABBREVIATION:FabH# NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabG# NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI# NAME:beta-hydroxydecanoyl thioester dehydrase#ABBREVIATION:FabA# NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_037) and (BLBBGE_079) or (BLBBGE_111) and (BLBBGE_057) and (BLBBGE_346)
product: 699475
reactant: 699427
reactant: 699403
fast: false

699355
stoichiometry: 14.0
species: 302723
type: SpeciesReference

303381
kinetic law: 705348
product: 705335
reactant: 705323
notes: Abbreviation: R_FRUt1r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: fru[e] <==> fru[c] Confidence Level: 2 genes: LOCUS:BLBBGE_199 proteins: NAME:ABC transporter, ATP-binding and permease protein citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_199)
fast: false
reversible: true
name: D-fructose transport in via uniport
type: Reaction

303630
product: 713805
product: 713793
notes: Abbreviation: R_OMPDC Synonyms: _0 EC Number: 4.1.1.23 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : h + orot5p --> co2 + ump Confidence Level: 2 genes: LOCUS:BLBBGE_512#ABBREVIATION:pyrFE#ECNUMBERS:4.1.1.23# proteins: NAME:Orotidine 5'-phosphate decarboxylase-Orotate phosphoribosyltransferase#ABBREVIATION:PyrFE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_512)
type: Reaction
name: orotidine-5'-phosphate decarboxylase
reversible: false
kinetic law: 713818
fast: false
reactant: 713781
reactant: 713769

302898
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: alpha-D-Ribose 5-phosphate_C5H9O8P
type: Species

696553
stoichiometry: 1.0
species: 302499
type: SpeciesReference

303067
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Succinate_C4H4O4
type: Species

304190
value: 999999.0
type: LocalParameter

302712
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Myristoyl-ACP (n-C14:0ACP)_C25H47N2O8PRS
type: Species

304220
value: 999999.0
type: LocalParameter

702953
stoichiometry: 1.0
species: 302865
type: SpeciesReference

304434
value: 0.0
type: LocalParameter

705518
stoichiometry: 2.0
species: 302659
type: SpeciesReference

701708
stoichiometry: 2.0
species: 302655
type: SpeciesReference

305707
value: 0.0
type: LocalParameter

721294
stoichiometry: 1.0
species: 302853
type: SpeciesReference

707413
stoichiometry: 1.0
species: 302670
type: SpeciesReference

707136
stoichiometry: 1.0
species: 302652
type: SpeciesReference

303920
value: 0.0
type: LocalParameter

712668
stoichiometry: 1.0
species: 302650
type: SpeciesReference

303719
type: Reaction
reversible: false
name: pyridoxal kinase
fast: false
product: 717371
notes: Abbreviation: R_PYDXK Synonyms: _0 EC Number: 2.7.1.35 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + pydx --> adp + h + pydx5p Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
kinetic law: 717407
reactant: 717359
product: 717395
product: 717383
reactant: 717347

303635
name: phospho-N-acetylmuramoyl-pentapeptide-transferase (meso-2,6-diaminopimelate)
reversible: false
notes: Abbreviation: R_PAPPT3 Synonyms: _0 EC Number: 2.7.8.13 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : udcpp + ugmda --> uagmda + ump Confidence Level: 2 genes: LOCUS:BLBBGE_389#ABBREVIATION:mraY#ECNUMBERS:2.7.8.13# proteins: NAME:Phospho-N-acetylmuramoyl-pentapeptide transferase#ABBREVIATION:MraY# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_389)
reactant: 713975
fast: false
product: 713999
type: Reaction
reactant: 713962
product: 713987
kinetic law: 714011

716850
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304435
value: 0.0
type: LocalParameter

304548
value: 999999.0
type: LocalParameter

304221
value: 0.0
type: LocalParameter

304193
value: -999999.0
type: LocalParameter

302934
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5,6,7,8-Tetrahydrofolate_C19H21N7O6
type: Species

698606
stoichiometry: 4.0E-4
species: 302724
type: SpeciesReference

304120
value: 0.0
type: LocalParameter

303171
product: 699331
product: 699367
product: 699319
reversible: false
reactant: 699295
reactant: 699271
type: Reaction
product: 699343
name: Fatty acid biosynthesis (n-C16:0)
notes: Abbreviation: R_C160SN Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : actACP + (20) h + (6) malACP + (14) nadph --> (6) ACP + (6) co2 + (7) h2o + (14) nadp + palmACP Confidence Level: 2 tv genes: LOCUS:BLBBGE_037#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-# LOCUS:BLBBGE_346#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9# LOCUS:BLBBGE_057#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100# LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.179# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabG# NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI# NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_037) and (BLBBGE_079) and (BLBBGE_346) and (BLBBGE_057)
reactant: 699307
reactant: 699283
fast: false
product: 699355
kinetic law: 699379

302493
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: ADP_C10H12N5O10P2
type: Species

713165
stoichiometry: 1.0
species: 302584
type: SpeciesReference

703002
stoichiometry: 1.0
species: 302893
type: SpeciesReference

305706
value: 0.0
type: LocalParameter

708287
stoichiometry: 1.0
species: 302680
type: SpeciesReference

717637
stoichiometry: 1.0
species: 302577
type: SpeciesReference

719002
stoichiometry: 1.0
species: 302432
type: SpeciesReference

721331
stoichiometry: 1.0
species: 302504
type: SpeciesReference

718733
stoichiometry: 1.0
species: 302493
type: SpeciesReference

303921
value: 0.0
type: LocalParameter

304879
value: 999999.0
type: LocalParameter

304549
value: 0.0
type: LocalParameter

694984
stoichiometry: 1.0
species: 302484
type: SpeciesReference

304436
value: 999999.0
type: LocalParameter

712339
stoichiometry: 1.0
species: 302534
type: SpeciesReference

707497
stoichiometry: 1.0
species: 302668
type: SpeciesReference

305379
value: 0.0
type: LocalParameter

302935
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Thiamin_C12H17N4OS
type: Species

303230
name: dihydrodipicolinate synthase
product: 701708
kinetic law: 701720
product: 701684
reactant: 701672
type: Reaction
reversible: false
reactant: 701660
fast: false
notes: Abbreviation: R_DHDPS Synonyms: _0 EC Number: 4.2.1.52 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : aspsa + pyr --> 23dhdp + h + (2) h2o Confidence Level: 2 genes: LOCUS:BLBBGE_210#ABBREVIATION:dapA#ECNUMBERS:4.2.1.52# proteins: NAME:Dihydrodipicolinate synthetase#ABBREVIATION:DapA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_210)
product: 701696

304222
value: 0.0
type: LocalParameter

304192
value: 0.0
type: LocalParameter

720919
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304121
value: 0.0
type: LocalParameter

302494
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Agmatine_C5H16N4
type: Species

303170
name: Fatty acid biosynthesis (n-C14:1)
notes: Abbreviation: R_C141SN Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : actACP + (16) h + (5) malACP + (11) nadph --> (5) ACP + (5) co2 + (6) h2o + (11) nadp + tdeACP Confidence Level: 2 tv genes: LOCUS:BLBBGE_037#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-# LOCUS:none#ABBREVIATION:fabA#ECNUMBERS:4.2.1.60# LOCUS:BLBBGE_346#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9# LOCUS:BLBBGE_057#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100# LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.179# LOCUS:BLBBGE_111#ABBREVIATION:fabH#ECNUMBERS:2.3.1.41# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase#ABBREVIATION:FabH# NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabG# NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI# NAME:beta-hydroxydecanoyl thioester dehydrase#ABBREVIATION:FabA# NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_037) and (BLBBGE_346) and (BLBBGE_057) and (BLBBGE_079) or (BLBBGE_111)
product: 699199
kinetic law: 699259
reactant: 699151
product: 699235
reversible: false
type: Reaction
product: 699211
product: 699247
reactant: 699187
product: 699223
reactant: 699175
reactant: 699163
fast: false

695687
stoichiometry: 1.0
species: 302659
type: SpeciesReference

708031
stoichiometry: 1.0
species: 302675
type: SpeciesReference

709776
stoichiometry: 1.0
species: 302698
type: SpeciesReference

303798
product: 721755
reversible: false
reactant: 721743
reactant: 721731
notes: Abbreviation: R_UHGADA Synonyms: _0 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : h2o + u3aga --> ac + u3hga Confidence Level: 2 tc genes: LOCUS:BLBBGE_037#ABBREVIATION:lpxC#ECNUMBERS:3.5.1.-# proteins: NAME:UDP-3-O-acyl-N-acetylglucosamine deacetylase#ABBREVIATION:LpxC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_037)
type: Reaction
fast: false
kinetic law: 721779
name: UDP-3-O-acetylglucosamine deacetylase
product: 721767

303922
value: 999999.0
type: LocalParameter

304437
value: 0.0
type: LocalParameter

718893
stoichiometry: 1.0
species: 302733
type: SpeciesReference

305709
value: 999999.0
type: LocalParameter

719364
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302893
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Pyruvate_C3H3O3
type: Species

702217
stoichiometry: 1.0
species: 302575
type: SpeciesReference

304223
value: 0.0
type: LocalParameter

304195
value: 0.0
type: LocalParameter

303410
kinetic law: 706401
product: 706389
reactant: 706377
notes: Abbreviation: R_GLUR Synonyms: _0 EC Number: 5.1.1.3 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : glu-D <==> glu-L Confidence Level: 2 genes: LOCUS:BLBBGE_411#ABBREVIATION:murI#ECNUMBERS:5.1.1.3# proteins: NAME:glutamate racemase#ABBREVIATION:MurI# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_411)
fast: false
reversible: true
name: glutamate racemase
type: Reaction

718154
stoichiometry: 1.0
species: 302626
type: SpeciesReference

304122
value: 999999.0
type: LocalParameter

303799
kinetic law: 721841
reactant: 721803
product: 721829
product: 721816
name: UMP kinase
reactant: 721791
fast: false
type: Reaction
notes: Abbreviation: R_UMPK Synonyms: _9 EC Number: 2.7.4.14 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + ump <==> adp + udp Confidence Level: 2 genes: LOCUS:BLBBGE_120#ABBREVIATION:pyrH#ECNUMBERS:2.7.4.-# LOCUS:BLBBGE_058#ABBREVIATION:cmk#ECNUMBERS:2.7.4.14# proteins: NAME:cytidine monophosphate kinase#ABBREVIATION:Cmk# NAME:uridylate kinase#ABBREVIATION:PyrH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_120) or (BLBBGE_058)
reversible: true

303923
value: 0.0
type: LocalParameter

718942
stoichiometry: 1.0
species: 302923
type: SpeciesReference

706039
stoichiometry: 1.0
species: 302526
type: SpeciesReference

715129
stoichiometry: 1.0
species: 302714
type: SpeciesReference

305708
value: 0.0
type: LocalParameter

304438
value: 0.0
type: LocalParameter

302894
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Pyruvate_C3H3O3
type: Species

303634
fast: false
reactant: 713914
reactant: 713902
kinetic law: 713950
product: 713926
name: _2-oxoglutarate decarboxylase
reactant: 713890
notes: Abbreviation: R_OXGDC2 Synonyms: _1 EC Number: 4.1.1.71 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : akg + h + thmpp --> co2 + ssaltpp Confidence Level: 2 JLR genes: LOCUS:BLBBGE_056#ABBREVIATION:menD#ECNUMBERS:4.1.1.71,-!-,2.2.1.9# proteins: NAME:bifunctional 2-oxoglutarate decarboxylase/2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase#ABBREVIATION:MenD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_056)
reversible: false
type: Reaction
product: 713938

715369
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304194
value: 999999.0
type: LocalParameter

304224
value: 999999.0
type: LocalParameter

302933
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2,3,4,5-Tetrahydrodipicolinate_C7H7NO4
type: Species

713793
stoichiometry: 1.0
species: 302536
type: SpeciesReference

305220
value: 0.0
type: LocalParameter

697906
stoichiometry: 1.0
species: 302519
type: SpeciesReference

304123
value: 0.0
type: LocalParameter

304010
value: 0.0
type: LocalParameter

696979
stoichiometry: 1.0
species: 302504
type: SpeciesReference

302492
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Adenosine_C10H13N5O4
type: Species

697335
stoichiometry: 1.0
species: 302893
type: SpeciesReference

701212
stoichiometry: 1.0
species: 302556
type: SpeciesReference

305670
value: 999999.0
type: LocalParameter

701356
stoichiometry: 1.0
species: 302593
type: SpeciesReference

304196
value: 0.0
type: LocalParameter

696348
stoichiometry: 1.0
species: 302482
type: SpeciesReference

304214
value: 0.0
type: LocalParameter

711201
stoichiometry: 1.0
species: 302660
type: SpeciesReference

695397
stoichiometry: 1.0
species: 302538
type: SpeciesReference

705481
stoichiometry: 1.0
species: 302618
type: SpeciesReference

700994
stoichiometry: 1.0
species: 302659
type: SpeciesReference

706111
stoichiometry: 1.0
species: 302629
type: SpeciesReference

712218
stoichiometry: 1.0
species: 302655
type: SpeciesReference

702434
stoichiometry: 1.0
species: 302655
type: SpeciesReference

700547
stoichiometry: 1.0
species: 302655
type: SpeciesReference

704345
stoichiometry: 1.0
species: 302765
type: SpeciesReference

303860
value: -999999.0
type: LocalParameter

302485
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N2-Acetyl-L-ornithine_C7H14N2O3
type: Species

712897
stoichiometry: 1.0
species: 302865
type: SpeciesReference

719786
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304197
value: 0.0
type: LocalParameter

698957
stoichiometry: 4.0
species: 302487
type: SpeciesReference

695458
stoichiometry: 1.0
species: 302477
type: SpeciesReference

701284
stoichiometry: 1.0
species: 302559
type: SpeciesReference

303221
kinetic law: 701416
reactant: 701380
type: Reaction
fast: false
reactant: 701356
reactant: 701368
product: 701392
name: _3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase
notes: Abbreviation: R_DDPA Synonyms: _0 EC Number: 2.5.1.54 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : e4p + h2o + pep --> 2dda7p + pi Confidence Level: 2 genes: LOCUS:BPLAN_296#ABBREVIATION:aroGpheA#ECNUMBERS:2.5.1.54,-!-,4.2.1.51,-!-,5.4.99.5# proteins: NAME:_bifunctional putative phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase#ABBREVIATION:AroGPheA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_344)
product: 701404
reversible: false

303639
kinetic law: 714203
product: 714191
name: Phosphatidic acid synthase
reactant: 714119
reversible: false
reactant: 714131
reactant: 714107
reactant: 714155
product: 714179
type: Reaction
fast: false
notes: Abbreviation: R_PASYN_Bge Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : glyc3p + (0.14) hdeACP + (0.04) myrsACP + octeACP + (0.72) palmACP + (0.1) tdeACP --> (2) ACP + (0.02) pa_Bge Confidence Level: 2 JLR genes: LOCUS:BLBBGE_508#ABBREVIATION:plsC#ECNUMBERS:2.3.1.51# LOCUS:BLBBGE_599#ABBREVIATION:plsB#ECNUMBERS:2.3.1.15# proteins: NAME:glycerolphosphate acyltransferase#ABBREVIATION:PlsB# NAME:_1-acyl-glycerol-3-phosphate acyltransferase#ABBREVIATION:PlsC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_508) and (BLBBGE_599)
reactant: 714143
reactant: 714167

706256
stoichiometry: 1.0
species: 302724
type: SpeciesReference

716261
stoichiometry: 1.0
species: 302853
type: SpeciesReference

710562
stoichiometry: 1.0
species: 302511
type: SpeciesReference

717152
stoichiometry: 1.0
species: 302853
type: SpeciesReference

305703
value: 0.0
type: LocalParameter

302550
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dAMP_C10H12N5O6P
type: Species

304198
value: 999999.0
type: LocalParameter

704237
stoichiometry: 1.0
species: 302718
type: SpeciesReference

302484
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-Acetyl-L-glutamate_C7H9NO5
type: Species

715700
stoichiometry: 1.0
species: 302973
type: SpeciesReference

695519
stoichiometry: 1.0
species: 302492
type: SpeciesReference

303224
kinetic law: 701476
name: deoxyguanylate kinase (dGMP:ATP)
product: 701464
reactant: 701440
fast: false
product: 701452
reversible: true
type: Reaction
notes: Abbreviation: R_DGK1 Synonyms: _0 EC Number: 2.7.4.8 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dgmp <==> adp + dgdp Confidence Level: 2 Added EC- JLR genes: LOCUS:BLBBGE_298#ABBREVIATION:gmk#ECNUMBERS:2.7.4.8# proteins: NAME:Guanylate kinase#ABBREVIATION:Gmk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_298)
reactant: 701428

713672
stoichiometry: 1.0
species: 302495
type: SpeciesReference

305508
value: 0.0
type: LocalParameter

304216
value: 999999.0
type: LocalParameter

714817
stoichiometry: 1.0
species: 302500
type: SpeciesReference

713527
stoichiometry: 5.0
species: 302687
type: SpeciesReference

303638
reversible: false
notes: Abbreviation: R_PAPSR Synonyms: _0 EC Number: 1.8.4.8 SUBSYSTEM: Cysteine Metabolism Equation: [c] : paps + trdrd --> (2) h + pap + so3 + trdox Confidence Level: 2 Previous EC 1.8.99.4. Now EC 1.8.4.8 genes: LOCUS:BLBBGE_273#ABBREVIATION:cysH#ECNUMBERS:1.8.4.8# proteins: NAME:_3'-phosphoadenosine 5'-phosphosulfate reductase#ABBREVIATION:CysH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_273)
name: phosphoadenylyl-sulfate reductase (thioredoxin)
kinetic law: 714095
reactant: 714023
fast: false
product: 714047
product: 714083
reactant: 714035
product: 714071
product: 714059
type: Reaction

708868
stoichiometry: 1.0
species: 302724
type: SpeciesReference

305704
value: 0.0
type: LocalParameter

304949
value: -999999.0
type: LocalParameter

705739
stoichiometry: 1.0
species: 302620
type: SpeciesReference

302405
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

302483
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-Acetyl-D-glucosamine 1-phosphate_C8H14NO9P
type: Species

304199
value: 0.0
type: LocalParameter

302551
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dATP_C10H12N5O12P3
type: Species

305671
value: 0.0
type: LocalParameter

303862
value: 999999.0
type: LocalParameter

717200
stoichiometry: 1.0
species: 302853
type: SpeciesReference

718238
stoichiometry: 1.0
species: 302924
type: SpeciesReference

305509
value: 0.0
type: LocalParameter

698245
stoichiometry: 3.0
species: 302659
type: SpeciesReference

694900
stoichiometry: 1.0
species: 302484
type: SpeciesReference

305705
value: 999999.0
type: LocalParameter

302406
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

716477
stoichiometry: 1.0
species: 302449
type: SpeciesReference

709219
stoichiometry: 1.0
species: 302487
type: SpeciesReference

304440
value: 0.0
type: LocalParameter

702590
stoichiometry: 1.0
species: 302538
type: SpeciesReference

696613
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305597
value: 999999.0
type: LocalParameter

705360
stoichiometry: 1.0
species: 302469
type: SpeciesReference

305674
value: 0.0
type: LocalParameter

302407
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _10-Formyltetrahydrofolate_C20H21N7O7
type: Species

304117
value: 0.0
type: LocalParameter

303863
value: 0.0
type: LocalParameter

712813
stoichiometry: 1.0
species: 302659
type: SpeciesReference

721695
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304947
value: 0.0
type: LocalParameter

303226
kinetic law: 701575
product: 701563
product: 701550
reactant: 701538
notes: Abbreviation: R_DHAD2 Synonyms: _0 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 23dhmp --> 3mop + h2o Confidence Level: 2 genes: LOCUS:BLBBGE_557#ABBREVIATION:ilvD#ECNUMBERS:4.2.1.9# proteins: NAME:dihidroxy acid dehydratase#ABBREVIATION:IlvD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_557)
fast: false
reversible: false
name: Dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate)
type: Reaction

720661
stoichiometry: 1.0
species: 302684
type: SpeciesReference

302618
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Fumarate_C4H2O4
type: Species

304218
value: 0.0
type: LocalParameter

701866
stoichiometry: 1.0
species: 302853
type: SpeciesReference

708589
stoichiometry: 1.0
species: 302435
type: SpeciesReference

706739
stoichiometry: 1.0
species: 302641
type: SpeciesReference

305506
value: 0.0
type: LocalParameter

305596
value: 0.0
type: LocalParameter

711287
stoichiometry: 1.0
species: 302493
type: SpeciesReference

302899
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Riboflavin_C17H20N4O6
type: Species

698824
stoichiometry: 0.7302
species: 302865
type: SpeciesReference

305673
value: 0.0
type: LocalParameter

303864
value: 0.0
type: LocalParameter

706328
stoichiometry: 1.0
species: 302633
type: SpeciesReference

304116
value: 0.0
type: LocalParameter

302489
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Acetoacetyl-ACP_C15H25N2O9PRS
type: Species

717576
stoichiometry: 1.0
species: 302606
type: SpeciesReference

302617
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Fumarate_C4H2O4
type: Species

715612
stoichiometry: 1.0
species: 302536
type: SpeciesReference

304946
value: 0.0
type: LocalParameter

701915
stoichiometry: 1.0
species: 302422
type: SpeciesReference

303225
kinetic law: 701526
product: 701514
product: 701502
reactant: 701489
notes: Abbreviation: R_DHAD1 Synonyms: _0 EC Number: 4.2.1.9 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 23dhmb --> 3mob + h2o Confidence Level: 2 genes: LOCUS:BLBBGE_557#ABBREVIATION:ilvD#ECNUMBERS:4.2.1.9# proteins: NAME:dihidroxy acid dehydratase#ABBREVIATION:IlvD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_557)
fast: false
reversible: false
name: dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate)
type: Reaction

714239
stoichiometry: 1.0
species: 302893
type: SpeciesReference

718529
stoichiometry: 1.0
species: 302432
type: SpeciesReference

304217
value: 0.0
type: LocalParameter

709899
stoichiometry: 1.0
species: 302893
type: SpeciesReference

302408
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Phospho-D-glyceroyl phosphate_C3H4O10P2
type: Species

305599
value: 0.0
type: LocalParameter

721816
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304442
value: 999999.0
type: LocalParameter

714311
stoichiometry: 1.0
species: 302758
type: SpeciesReference

305676
value: 0.0
type: LocalParameter

302929
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: O-Succinyl-L-homoserine_C8H12NO6
type: Species

303865
value: 0.0
type: LocalParameter

302488
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: O-Acetyl-L-serine_C5H9NO4
type: Species

304119
value: 0.0
type: LocalParameter

719436
stoichiometry: 3.0
species: 302723
type: SpeciesReference

305700
value: 999999.0
type: LocalParameter

302409
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _1-Pyrroline-5-carboxylate_C5H6NO2
type: Species

714757
stoichiometry: 1.0
species: 302660
type: SpeciesReference

304945
value: 999999.0
type: LocalParameter

719581
stoichiometry: 1.0
species: 302933
type: SpeciesReference

305598
value: 0.0
type: LocalParameter

305675
value: 999999.0
type: LocalParameter

302928
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Succinyl-CoA_C25H35N7O19P3S
type: Species

710301
stoichiometry: 1.0
species: 302723
type: SpeciesReference

302487
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: acyl carrier protein_C11H21N2O7PRS
type: Species

304118
value: 999999.0
type: LocalParameter

303866
value: 999999.0
type: LocalParameter

305701
value: 0.0
type: LocalParameter

715588
stoichiometry: 1.0
species: 302659
type: SpeciesReference

715021
stoichiometry: 1.0
species: 302466
type: SpeciesReference

304944
value: -999999.0
type: LocalParameter

305505
value: 999999.0
type: LocalParameter

721125
stoichiometry: 1.0
species: 302865
type: SpeciesReference

304219
value: 0.0
type: LocalParameter

304327
value: 0.0
type: LocalParameter

305218
value: 0.0
type: LocalParameter

302556
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dCMP_C9H12N3O7P
type: Species

702192
stoichiometry: 1.0
species: 302450
type: SpeciesReference

302614
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Fructose_C6H12O6
type: Species

704804
stoichiometry: 1.0
species: 303073
type: SpeciesReference

304008
value: 0.0
type: LocalParameter

712922
stoichiometry: 1.0
species: 302541
type: SpeciesReference

705251
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305593
value: 999999.0
type: LocalParameter

709171
stoichiometry: 2.0
species: 302659
type: SpeciesReference

711177
stoichiometry: 1.0
species: 302865
type: SpeciesReference

304686
value: 0.0
type: LocalParameter

305503
value: 0.0
type: LocalParameter

303229
fast: false
notes: Abbreviation: R_DHDPRy Synonyms: _0 EC Number: 1.3.1.26 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : 23dhdp + h + nadph --> nadp + thdp Confidence Level: 2 genes: LOCUS:BLBBGE_551#ABBREVIATION:dapB#ECNUMBERS:1.3.1.26# proteins: NAME:Dihydrodipicolinate reductase#ABBREVIATION:DapB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_551)
kinetic law: 701648
reactant: 701587
reactant: 701599
reversible: false
name: dihydrodipicolinate reductase (NADPH)
type: Reaction
product: 701624
reactant: 701611
product: 701636

304326
value: 0.0
type: LocalParameter

305217
value: 999999.0
type: LocalParameter

709812
stoichiometry: 1.0
species: 302720
type: SpeciesReference

698130
stoichiometry: 1.0
species: 302526
type: SpeciesReference

717757
stoichiometry: 1.0
species: 302548
type: SpeciesReference

708431
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302557
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dCTP_C9H12N3O13P3
type: Species

304007
value: 0.0
type: LocalParameter

302613
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Farnesyl diphosphate_C15H25O7P2
type: Species

702675
stoichiometry: 1.0
species: 302687
type: SpeciesReference

698715
stoichiometry: 2.23E-4
species: 302939
type: SpeciesReference

305592
value: 0.0
type: LocalParameter

715996
stoichiometry: 1.0
species: 302461
type: SpeciesReference

304685
value: 999999.0
type: LocalParameter

700331
stoichiometry: 1.0
species: 302853
type: SpeciesReference

303566
fast: false
type: Reaction
reactant: 711759
reactant: 711747
notes: Abbreviation: R_NDPK9 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + idp <==> adp + itp Confidence Level: 2 NCD genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Sabree, Z.L., Kambhampati, S., Moran, N.A.#TITLE:Nitrogen recycling and nutritional provisioning by Blattabacterium, the cockroach endosymbiont.#JOURNAL:Proc Natl Acad Sci U S A.#YEAR:2009#PUBMED: 19880743# GENE ASSOCIATION: (BLBBGE_453)
product: 711783
kinetic law: 711795
name: nucleoside-diphosphate kinase (ATP:IDP)
product: 711771
reversible: true

304329
value: 0.0
type: LocalParameter

304688
value: -999999.0
type: LocalParameter

714071
stoichiometry: 1.0
species: 302915
type: SpeciesReference

712789
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302616
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: D-Fructose_C6H12O6
type: Species

707353
stoichiometry: 1.0
species: 302659
type: SpeciesReference

721548
stoichiometry: 1.0
species: 302974
type: SpeciesReference

697226
stoichiometry: 1.0
species: 302880
type: SpeciesReference

700043
stoichiometry: 1.0
species: 302659
type: SpeciesReference

721925
stoichiometry: 1.0
species: 302985
type: SpeciesReference

305500
value: 0.0
type: LocalParameter

305442
value: 0.0
type: LocalParameter

304551
value: 0.0
type: LocalParameter

305595
value: 0.0
type: LocalParameter

305219
value: 0.0
type: LocalParameter

304328
value: 999999.0
type: LocalParameter

303567
kinetic law: 711831
product: 711819
reactant: 711807
notes: Abbreviation: R_NH4t Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: nh4[e] <==> nh4[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: ammonia reversible transport
type: Reaction

304600
value: 999999.0
type: LocalParameter

302559
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Deoxycytidine_C9H13N3O4
type: Species

720029
stoichiometry: 1.0
species: 302620
type: SpeciesReference

710056
stoichiometry: 1.0
species: 302509
type: SpeciesReference

719509
stoichiometry: 1.0
species: 302903
type: SpeciesReference

305501
value: 0.0
type: LocalParameter

304687
value: 0.0
type: LocalParameter

695179
stoichiometry: 1.0
species: 302479
type: SpeciesReference

304550
value: 0.0
type: LocalParameter

305441
value: 999999.0
type: LocalParameter

305594
value: 0.0
type: LocalParameter

699511
stoichiometry: 1.0
species: 302489
type: SpeciesReference

705593
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302610
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine_C8H15N3O8P
type: Species

702325
stoichiometry: 1.0
species: 302438
type: SpeciesReference

304601
value: 0.0
type: LocalParameter

304726
value: 0.0
type: LocalParameter

708504
stoichiometry: 1.0
species: 302659
type: SpeciesReference

696529
stoichiometry: 1.0
species: 302934
type: SpeciesReference

304323
value: -999999.0
type: LocalParameter

700885
stoichiometry: 1.0
species: 302576
type: SpeciesReference

305444
value: 0.0
type: LocalParameter

710165
stoichiometry: 1.0
species: 302526
type: SpeciesReference

302552
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3,4-dihydroxy-2-butanone 4-phosphate_C4H7O6P
type: Species

717359
stoichiometry: 1.0
species: 302890
type: SpeciesReference

713019
stoichiometry: 1.0
species: 302550
type: SpeciesReference

695032
stoichiometry: 1.0
species: 302427
type: SpeciesReference

304689
value: 999999.0
type: LocalParameter

304602
value: 0.0
type: LocalParameter

304727
value: 999999.0
type: LocalParameter

700655
stoichiometry: 1.0
species: 302546
type: SpeciesReference

712133
stoichiometry: 1.0
species: 302999
type: SpeciesReference

304322
value: 0.0
type: LocalParameter

719677
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303378
kinetic law: 705311
product: 705299
reactant: 705287
notes: Abbreviation: R_FORt Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: for[e] <==> for[c] Confidence Level: 1 renamed from FORTR to FORt NCD genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: formate transport via diffusion
type: Reaction

720775
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304088
value: 999999.0
type: LocalParameter

699427
stoichiometry: 13.0
species: 302724
type: SpeciesReference

716405
stoichiometry: 1.0
species: 302511
type: SpeciesReference

302554
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N6-(1,2-Dicarboxyethyl)-AMP_C14H14N5O11P
type: Species

302612
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide_C10H13N4O9P
type: Species

304325
value: 0.0
type: LocalParameter

716585
stoichiometry: 1.0
species: 302633
type: SpeciesReference

304728
value: 0.0
type: LocalParameter

718468
stoichiometry: 1.0
species: 302908
type: SpeciesReference

703726
stoichiometry: 1.0
species: 302637
type: SpeciesReference

305446
value: 999999.0
type: LocalParameter

303562
reactant: 711638
product: 711650
notes: Abbreviation: R_NDPK7 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dcdp <==> adp + dctp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions. genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)
product: 711663
reversible: true
fast: false
type: Reaction
reactant: 711626
kinetic law: 711675
name: nucleoside-diphosphate kinase (ATP:dCDP)

304089
value: 0.0
type: LocalParameter

305591
value: 0.0
type: LocalParameter

707280
stoichiometry: 1.0
species: 302662
type: SpeciesReference

720234
stoichiometry: 1.0
species: 302944
type: SpeciesReference

304729
value: 0.0
type: LocalParameter

705847
stoichiometry: 1.0
species: 302605
type: SpeciesReference

302555
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dCDP_C9H12N3O10P2
type: Species

304604
value: 0.0
type: LocalParameter

701054
stoichiometry: 1.0
species: 302417
type: SpeciesReference

305445
value: -999999.0
type: LocalParameter

304324
value: 999999.0
type: LocalParameter

303563
notes: Abbreviation: R_NDPK8 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dadp <==> adp + datp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions. genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)
name: nucleoside-diphosphate kinase (ATP:dADP)
reversible: true
product: 711723
kinetic law: 711735
reactant: 711687
type: Reaction
product: 711711
fast: false
reactant: 711699

703872
stoichiometry: 1.0
species: 302656
type: SpeciesReference

705763
stoichiometry: 1.0
species: 302853
type: SpeciesReference

702795
stoichiometry: 1.0
species: 302493
type: SpeciesReference

305392
value: 0.0
type: LocalParameter

304022
value: 0.0
type: LocalParameter

302720
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2
type: Species

713962
stoichiometry: 1.0
species: 302974
type: SpeciesReference

305431
value: 999999.0
type: LocalParameter

304796
value: 0.0
type: LocalParameter

700211
stoichiometry: 1.0
species: 302633
type: SpeciesReference

702060
stoichiometry: 1.0
species: 302748
type: SpeciesReference

304715
value: 999999.0
type: LocalParameter

715261
stoichiometry: 1.0
species: 302860
type: SpeciesReference

305636
value: 0.0
type: LocalParameter

302413
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate_C13H15N4O12P
type: Species

695044
stoichiometry: 1.0
species: 302659
type: SpeciesReference

719206
stoichiometry: 1.0
species: 302709
type: SpeciesReference

305749
value: 0.0
type: LocalParameter

705955
stoichiometry: 1.0
species: 302720
type: SpeciesReference

710177
stoichiometry: 1.0
species: 302706
type: SpeciesReference

304021
value: 0.0
type: LocalParameter

699536
stoichiometry: 7.0
species: 302697
type: SpeciesReference

304660
value: 0.0
type: LocalParameter

698169
stoichiometry: 1.0
species: 302873
type: SpeciesReference

720811
stoichiometry: 1.0
species: 302500
type: SpeciesReference

305432
value: 0.0
type: LocalParameter

304797
value: 999999.0
type: LocalParameter

305320
value: 0.0
type: LocalParameter

303446
product: 707581
kinetic law: 707593
notes: Abbreviation: R_HMBS Synonyms: _0 EC Number: 4.3.1.8 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : h2o + (4) ppbng --> hmbil + (4) nh4 Confidence Level: 2 genes: LOCUS:BLBBGE_573#ABBREVIATION:hemC#ECNUMBERS:4.3.1.8# proteins: NAME:Hydroxymethylbilane synthase#ABBREVIATION:HemC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_573)
reactant: 707557
fast: false
type: Reaction
reversible: false
name: hydroxymethylbilane synthase
reactant: 707545
product: 707569

718881
stoichiometry: 1.0
species: 302654
type: SpeciesReference

699681
stoichiometry: 2.0
species: 302526
type: SpeciesReference

304714
value: 0.0
type: LocalParameter

719521
stoichiometry: 1.0
species: 302593
type: SpeciesReference

303910
value: 0.0
type: LocalParameter

305635
value: 0.0
type: LocalParameter

714517
stoichiometry: 1.0
species: 302720
type: SpeciesReference

705835
stoichiometry: 1.0
species: 302624
type: SpeciesReference

305390
value: 999999.0
type: LocalParameter

304020
value: 999999.0
type: LocalParameter

715972
stoichiometry: 1.0
species: 302874
type: SpeciesReference

705130
stoichiometry: 1.0
species: 302853
type: SpeciesReference

303443
product: 707521
name: histidinol-phosphatase
product: 707509
type: Reaction
reactant: 707485
notes: Abbreviation: R_HISTP Synonyms: _0 EC Number: 3.1.3.15 SUBSYSTEM: Histidine Metabolism Equation: [c] : h2o + hisp --> histd + pi Confidence Level: 2 genes: LOCUS:BLBBGE_436#ABBREVIATION:hisB#ECNUMBERS:3.1.3.15,-!-,4.2.1.19# proteins: NAME:Imidazoleglycerol phosphate dehydratase and Histidinol phosphatase#ABBREVIATION:HisB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_436)
reactant: 707497
kinetic law: 707533
reversible: false
fast: false

304794
value: 0.0
type: LocalParameter

305433
value: 0.0
type: LocalParameter

711056
stoichiometry: 1.0
species: 302719
type: SpeciesReference

304717
value: 0.0
type: LocalParameter

711129
stoichiometry: 1.0
species: 302880
type: SpeciesReference

304508
value: 0.0
type: LocalParameter

694972
stoichiometry: 1.0
species: 302633
type: SpeciesReference

707485
stoichiometry: 1.0
species: 302655
type: SpeciesReference

706509
stoichiometry: 1.0
species: 302636
type: SpeciesReference

303338
kinetic law: 704405
product: 704393
reactant: 704381
notes: Abbreviation: R_EX_pi_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : pi <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Phosphate exchange
type: Reaction

702084
stoichiometry: 1.0
species: 302572
type: SpeciesReference

302411
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (R)-2,3-Dihydroxy-3-methylbutanoate_C5H9O4
type: Species

302637
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Glycine_C2H5NO2
type: Species

305634
value: 999999.0
type: LocalParameter

305747
value: 0.0
type: LocalParameter

305633
value: -999999.0
type: LocalParameter

717709
stoichiometry: 1.0
species: 302899
type: SpeciesReference

305391
value: 0.0
type: LocalParameter

715875
stoichiometry: 1.0
species: 302610
type: SpeciesReference

304795
value: 0.0
type: LocalParameter

303289
kinetic law: 703497
product: 703485
reactant: 703473
notes: Abbreviation: R_EX_dhor_S_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : dhor-S <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: S-Dihydroorotate
type: Reaction

305434
value: 0.0
type: LocalParameter

712656
stoichiometry: 1.0
species: 302655
type: SpeciesReference

720390
stoichiometry: 1.0
species: 302723
type: SpeciesReference

304716
value: 0.0
type: LocalParameter

302638
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Glyceraldehyde_C3H6O3
type: Species

302412
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (R)-2,3-Dihydroxy-3-methylpentanoate_C6H11O4
type: Species

715441
stoichiometry: 1.0
species: 302542
type: SpeciesReference

704828
stoichiometry: 1.0
species: 302988
type: SpeciesReference

694826
stoichiometry: 1.0
species: 302662
type: SpeciesReference

703982
stoichiometry: 1.0
species: 302680
type: SpeciesReference

305746
value: 999999.0
type: LocalParameter

717649
stoichiometry: 2.0
species: 302655
type: SpeciesReference

303393
fast: false
product: 705691
kinetic law: 705727
name: L-glutamate 5-semialdehyde dehydratase (spontaneous)
reactant: 705679
type: Reaction
product: 705703
reversible: false
product: 705715
notes: Abbreviation: R_G5SADs Synonyms: _0 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : glu5sa --> 1pyr5c + h + h2o Confidence Level: 1 Needed in L-proline biosynthesis genes: none proteins: none citations: none GENE ASSOCIATION:

305325
value: 0.0
type: LocalParameter

700175
stoichiometry: 1.0
species: 302990
type: SpeciesReference

712011
stoichiometry: 1.0
species: 302569
type: SpeciesReference

695203
stoichiometry: 1.0
species: 302538
type: SpeciesReference

704030
stoichiometry: 1.0
species: 303040
type: SpeciesReference

302724
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3
type: Species

702941
stoichiometry: 1.0
species: 302659
type: SpeciesReference

701440
stoichiometry: 1.0
species: 302562
type: SpeciesReference

704456
stoichiometry: 1.0
species: 302863
type: SpeciesReference

305632
value: 0.0
type: LocalParameter

697665
stoichiometry: 1.0
species: 302516
type: SpeciesReference

697943
stoichiometry: 1.0
species: 302522
type: SpeciesReference

718323
stoichiometry: 1.0
species: 302675
type: SpeciesReference

304719
value: 999999.0
type: LocalParameter

695903
stoichiometry: 1.0
species: 302688
type: SpeciesReference

700763
stoichiometry: 1.0
species: 302528
type: SpeciesReference

305324
value: 999999.0
type: LocalParameter

707896
stoichiometry: 1.0
species: 302682
type: SpeciesReference

302725
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Ammonium_H4N
type: Species

709183
stoichiometry: 1.0
species: 302697
type: SpeciesReference

303442
product: 707437
type: Reaction
product: 707461
reversible: false
fast: false
reactant: 707413
notes: Abbreviation: R_HISTD Synonyms: _0 EC Number: 1.1.1.23 SUBSYSTEM: Histidine Metabolism Equation: [c] : h2o + histd + (2) nad --> (3) h + his-L + (2) nadh Confidence Level: 2 genes: LOCUS:BLBBGE_434#ABBREVIATION:hisD#ECNUMBERS:1.1.1.23# proteins: NAME:Histidinol dehydrogenase#ABBREVIATION:HisD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_434)
product: 707449
reactant: 707425
name: histidinol dehydrogenase
kinetic law: 707473
reactant: 707401

302410
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2,3-Dihydrodipicolinate_C7H5NO4
type: Species

721368
stoichiometry: 1.0
species: 302493
type: SpeciesReference

305631
value: 0.0
type: LocalParameter

304718
value: 0.0
type: LocalParameter

716549
stoichiometry: 0.02
species: 302759
type: SpeciesReference

302636
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Glycine_C2H5NO2
type: Species

304469
value: 0.0
type: LocalParameter

710790
stoichiometry: 1.0
species: 302720
type: SpeciesReference

715662
stoichiometry: 1.0
species: 302960
type: SpeciesReference

698449
stoichiometry: 0.25
species: 302628
type: SpeciesReference

303286
kinetic law: 703461
product: 703449
reactant: 703436
notes: Abbreviation: R_EX_cys_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : cys-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Cysteine exchange
type: Reaction

695167
stoichiometry: 1.0
species: 302487
type: SpeciesReference

720895
stoichiometry: 1.0
species: 302969
type: SpeciesReference

696288
stoichiometry: 1.0
species: 302494
type: SpeciesReference

305630
value: 999999.0
type: LocalParameter

710020
stoichiometry: 1.0
species: 302526
type: SpeciesReference

720535
stoichiometry: 1.0
species: 302655
type: SpeciesReference

717925
stoichiometry: 1.0
species: 302948
type: SpeciesReference

701126
stoichiometry: 1.0
species: 302865
type: SpeciesReference

707605
stoichiometry: 1.0
species: 302473
type: SpeciesReference

303879
value: 0.0
type: LocalParameter

302633
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Glutamate_C5H8NO4
type: Species

706341
stoichiometry: 1.0
species: 302865
type: SpeciesReference

304931
value: 0.0
type: LocalParameter

700825
stoichiometry: 1.0
species: 302555
type: SpeciesReference

716693
stoichiometry: 0.02
species: 302529
type: SpeciesReference

702819
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304468
value: 0.0
type: LocalParameter

304798
value: 0.0
type: LocalParameter

708625
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304467
value: -999999.0
type: LocalParameter

302723
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3
type: Species

305322
value: 0.0
type: LocalParameter

704792
stoichiometry: 1.0
species: 302955
type: SpeciesReference

303499
product: 709436
fast: false
type: Reaction
notes: Abbreviation: R_LEUabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + leu-L[e] --> adp[c] + h[c] + leu-L[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 709460
kinetic law: 709485
name: L-leucine transport via ABC system
reactant: 709412
reactant: 709400
product: 709448
reactant: 709424
product: 709473
reversible: false

303285
kinetic law: 703424
product: 703412
reactant: 703399
notes: Abbreviation: R_EX_co2_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : co2 <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: CO2 exchange
type: Reaction

305430
value: 0.0
type: LocalParameter

714383
stoichiometry: 1.0
species: 302770
type: SpeciesReference

699839
stoichiometry: 1.0
species: 302449
type: SpeciesReference

303390
reactant: 705630
reversible: true
kinetic law: 705667
reactant: 705617
notes: Abbreviation: R_G3PD5 Synonyms: _0 EC Number: 1.1.5.3 SUBSYSTEM: Oxidative Phosphorylation Equation: [c] : glyc3p + mqn8 <==> dhap + mql8 Confidence Level: 2 JLR genes: LOCUS:BLBBGE_458#ABBREVIATION:glpD#ECNUMBERS:1.1.5.3# proteins: NAME:glycerol-3-phosphate dehydrogenase#ABBREVIATION:GlpD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_458)
type: Reaction
product: 705643
name: glycerol-3-phosphate dehydrogenase (ubiquinone-8)
product: 705655
fast: false

721913
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302634
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Glutamate_C5H8NO4
type: Species

304930
value: 0.0
type: LocalParameter

717395
stoichiometry: 1.0
species: 302889
type: SpeciesReference

716044
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304799
value: 0.0
type: LocalParameter

708528
stoichiometry: 1.0
species: 302998
type: SpeciesReference

696991
stoichiometry: 1.0
species: 302659
type: SpeciesReference

696881
stoichiometry: 1.0
species: 302659
type: SpeciesReference

717285
stoichiometry: 1.0
species: 302888
type: SpeciesReference

709037
stoichiometry: 1.0
species: 302489
type: SpeciesReference

305809
value: 0.0
type: LocalParameter

718214
stoichiometry: 1.0
species: 302913
type: SpeciesReference

699007
stoichiometry: 10.0
species: 302723
type: SpeciesReference

305216
value: 0.0
type: LocalParameter

697078
stoichiometry: 1.0
species: 302504
type: SpeciesReference

303919
value: 0.0
type: LocalParameter

720463
stoichiometry: 1.0
species: 302620
type: SpeciesReference

304828
value: 0.0
type: LocalParameter

719690
stoichiometry: 1.0
species: 302853
type: SpeciesReference

302526
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: ATP_C10H12N5O13P3
type: Species

302728
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Ammonium_H4N
type: Species

697834
stoichiometry: 1.0
species: 302524
type: SpeciesReference

305741
value: 0.0
type: LocalParameter

303982
value: 0.0
type: LocalParameter

304175
value: 0.0
type: LocalParameter

697556
stoichiometry: 1.0
species: 302494
type: SpeciesReference

303099
name: _4-amino-4-deoxychorismate synthase
product: 695759
notes: Abbreviation: R_ADCS Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : chor + gln-L --> 4adcho + glu-L Confidence Level: 2 Not in IUBMB. No EC genes: LOCUS:BLBBGE_421#ABBREVIATION:trpE#ECNUMBERS:6.3.5.8# LOCUS:BLBBGE_422#ABBREVIATION:trpD#ECNUMBERS:6.3.5.8# proteins: NAME:p-aminobenzoate synthetase, component II#ABBREVIATION:TrpD# NAME:p-aminobenzoate synthetase, component I#ABBREVIATION:TrpE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_421) and (BLBBGE_422)
kinetic law: 695771
reactant: 695723
type: Reaction
product: 695747
reactant: 695735
reversible: false
fast: false

698389
stoichiometry: 0.0365
species: 302551
type: SpeciesReference

303397
product: 705859
reactant: 705835
notes: Abbreviation: R_GARFT Synonyms: _1 EC Number: 2.1.2.2 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : 10fthf + gar --> fgam + h + thf Confidence Level: 2 genes: LOCUS:BLBBGE_481#ABBREVIATION:purN#ECNUMBERS:2.1.2.2# proteins: NAME:phosphoribosylglycinamide formytransferase#ABBREVIATION:PurN# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_481)
fast: false
type: Reaction
kinetic law: 705883
name: phosphoribosylglycinamide formyltransferase
reactant: 705823
reversible: false
product: 705871
product: 705847

303918
value: 999999.0
type: LocalParameter

303009
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Asparagine_C4H8N2O3
type: Species

304827
value: 0.0
type: LocalParameter

705617
stoichiometry: 1.0
species: 302641
type: SpeciesReference

302527
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Carbamoyl phosphate_CH2NO5P
type: Species

696204
stoichiometry: 1.0
species: 302651
type: SpeciesReference

718808
stoichiometry: 1.0
species: 302544
type: SpeciesReference

302729
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Nicotinate D-ribonucleotide_C11H12NO9P
type: Species

304174
value: 0.0
type: LocalParameter

303983
value: 0.0
type: LocalParameter

700283
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305280
value: -999999.0
type: LocalParameter

305740
value: 999999.0
type: LocalParameter

305215
value: 0.0
type: LocalParameter

720687
stoichiometry: 1.0
species: 302660
type: SpeciesReference

303333
kinetic law: 704297
product: 704285
reactant: 704273
notes: Abbreviation: R_EX_nh4_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : nh4 <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Ammonia exchange
type: Reaction

706232
stoichiometry: 1.0
species: 302500
type: SpeciesReference

710682
stoichiometry: 3.0
species: 302659
type: SpeciesReference

303008
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Arginine_C6H15N4O2
type: Species

303917
value: 0.0
type: LocalParameter

305807
value: 999999.0
type: LocalParameter

708734
stoichiometry: 1.0
species: 302436
type: SpeciesReference

717176
stoichiometry: 1.0
species: 302674
type: SpeciesReference

304028
value: -999999.0
type: LocalParameter

702482
stoichiometry: 1.0
species: 302497
type: SpeciesReference

302524
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Aspartate 4-semialdehyde_C4H7NO3
type: Species

303282
kinetic law: 703387
product: 703375
reactant: 703363
notes: Abbreviation: R_EX_asp_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : asp-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Aspartate exchange
type: Reaction

303980
value: 999999.0
type: LocalParameter

698078
stoichiometry: 1.0
species: 302522
type: SpeciesReference

302879
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Proline_C5H9NO2
type: Species

706437
stoichiometry: 1.0
species: 302633
type: SpeciesReference

305214
value: 0.0
type: LocalParameter

714493
stoichiometry: 1.0
species: 302719
type: SpeciesReference

303330
kinetic law: 704261
product: 704249
reactant: 704237
notes: Abbreviation: R_EX_nac_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : nac <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Nicotinate exchange
type: Reaction

304173
value: 0.0
type: LocalParameter

303916
value: 0.0
type: LocalParameter

708419
stoichiometry: 1.0
species: 302612
type: SpeciesReference

706135
stoichiometry: 1.0
species: 302493
type: SpeciesReference

305808
value: 0.0
type: LocalParameter

711336
stoichiometry: 1.0
species: 302975
type: SpeciesReference

304829
value: 999999.0
type: LocalParameter

305059
value: 0.0
type: LocalParameter

303981
value: 0.0
type: LocalParameter

303281
kinetic law: 703351
product: 703339
reactant: 703327
notes: Abbreviation: R_EX_asn_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : asn-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Asparagine exchange
type: Reaction

713249
stoichiometry: 1.0
species: 302865
type: SpeciesReference

701236
stoichiometry: 1.0
species: 302655
type: SpeciesReference

701332
stoichiometry: 1.0
species: 302725
type: SpeciesReference

303394
product: 705775
reactant: 705763
product: 705799
reactant: 705751
name: glyceraldehyde-3-phosphate dehydrogenase
fast: false
reactant: 705739
type: Reaction
product: 705787
kinetic law: 705811
notes: Abbreviation: R_GAPD Synonyms: _0 EC Number: 1.2.1.12 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : g3p + nad + pi <==> 13dpg + h + nadh Confidence Level: 2 SMP genes: LOCUS:BLBBGE_043#ABBREVIATION:gapA#ECNUMBERS:1.2.1.12# proteins: NAME:glyceraldehyde-3-phosphate dehydrogenase A#ABBREVIATION:GapA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_043)
reversible: true

304172
value: 999999.0
type: LocalParameter

305213
value: 999999.0
type: LocalParameter

305058
value: 0.0
type: LocalParameter

303986
value: 0.0
type: LocalParameter

719315
stoichiometry: 1.0
species: 302526
type: SpeciesReference

305805
value: 0.0
type: LocalParameter

303915
value: 0.0
type: LocalParameter

304249
value: -999999.0
type: LocalParameter

304824
value: -999999.0
type: LocalParameter

719835
stoichiometry: 1.0
species: 302427
type: SpeciesReference

304321
value: 0.0
type: LocalParameter

305212
value: 0.0
type: LocalParameter

699766
stoichiometry: 2.0
species: 302659
type: SpeciesReference

304026
value: 0.0
type: LocalParameter

304179
value: -999999.0
type: LocalParameter

305283
value: 0.0
type: LocalParameter

303987
value: 0.0
type: LocalParameter

305744
value: 0.0
type: LocalParameter

305057
value: 999999.0
type: LocalParameter

305806
value: -999999.0
type: LocalParameter

707713
stoichiometry: 1.0
species: 302672
type: SpeciesReference

303914
value: 999999.0
type: LocalParameter

303005
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Alanine_C3H7NO2
type: Species

303337
kinetic law: 704369
product: 704357
reactant: 704345
notes: Abbreviation: R_EX_phe_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : phe-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Phenylalanine exchange
type: Reaction

304823
value: 0.0
type: LocalParameter

719412
stoichiometry: 3.0
species: 302655
type: SpeciesReference

305541
value: 0.0
type: LocalParameter

700103
stoichiometry: 1.0
species: 302725
type: SpeciesReference

705493
stoichiometry: 2.0
species: 302660
type: SpeciesReference

305211
value: 0.0
type: LocalParameter

302878
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Proline_C5H9NO2
type: Species

304320
value: 999999.0
type: LocalParameter

720968
stoichiometry: 1.0
species: 302441
type: SpeciesReference

304025
value: 0.0
type: LocalParameter

721767
stoichiometry: 1.0
species: 302959
type: SpeciesReference

304178
value: 0.0
type: LocalParameter

305803
value: 999999.0
type: LocalParameter

305638
value: -999999.0
type: LocalParameter

302528
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: CDP_C9H12N3O11P2
type: Species

305056
value: 0.0
type: LocalParameter

716333
stoichiometry: 1.0
species: 302879
type: SpeciesReference

303984
value: 999999.0
type: LocalParameter

714625
stoichiometry: 1.0
species: 302659
type: SpeciesReference

695627
stoichiometry: 1.0
species: 302674
type: SpeciesReference

304826
value: 0.0
type: LocalParameter

303447
kinetic law: 707665
name: _6-hydroxymethyl-dihydropterin pyrophosphokinase
type: Reaction
notes: Abbreviation: R_HPPK2 Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 6hmhpt + atp --> 6hmhptpp + amp + h Confidence Level: 2 JLR- Neidhardt pg 667 genes: LOCUS:BLBBGE_627#ABBREVIATION:folK#ECNUMBERS:2.7.6.3# proteins: NAME:_7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase#ABBREVIATION:FolK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_627)
product: 707653
reactant: 707617
reactant: 707605
fast: false
product: 707641
product: 707629
reversible: false

702265
stoichiometry: 1.0
species: 302438
type: SpeciesReference

303004
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: _2-Oxoglutarate_C5H4O5
type: Species

305210
value: 0.0
type: LocalParameter

303334
kinetic law: 704333
product: 704321
reactant: 704309
notes: Abbreviation: R_EX_o2_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : o2 <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: O2 exchange
type: Reaction

706847
stoichiometry: 1.0
species: 302998
type: SpeciesReference

303097
reversible: false
fast: false
reactant: 695591
reactant: 695615
name: adenine deaminase
reactant: 695603
type: Reaction
notes: Abbreviation: R_ADD Synonyms: _0 EC Number: 3.5.4.2 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : ade + h + h2o --> hxan + nh4 Confidence Level: 1 note: reaction also occures spontaneously - oxidative deaminination (MKA) genes: none proteins: none citations: none GENE ASSOCIATION:
product: 695627
kinetic law: 695651
product: 695639

302875
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
type: Species

304177
value: 0.0
type: LocalParameter

705554
stoichiometry: 1.0
species: 302621
type: SpeciesReference

698933
stoichiometry: 4.0
species: 302697
type: SpeciesReference

305281
value: 999999.0
type: LocalParameter

717309
stoichiometry: 1.0
species: 302725
type: SpeciesReference

304024
value: 999999.0
type: LocalParameter

715765
stoichiometry: 1.0
species: 302493
type: SpeciesReference

303912
value: 0.0
type: LocalParameter

721197
stoichiometry: 1.0
species: 302960
type: SpeciesReference

305055
value: 0.0
type: LocalParameter

305804
value: 0.0
type: LocalParameter

704719
stoichiometry: 1.0
species: 302943
type: SpeciesReference

303985
value: 0.0
type: LocalParameter

721257
stoichiometry: 1.0
species: 302968
type: SpeciesReference

304825
value: 999999.0
type: LocalParameter

302529
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: CDPdiacylglycerol (Blattabacterium Blattella germanica)_C2286H3998N150O750P100
type: Species

303398
notes: Abbreviation: R_GCALDD Synonyms: _0 EC Number: 1.2.1.21 SUBSYSTEM: Folate Metabolism Equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 705895
reactant: 705919
kinetic law: 705967
type: Reaction
name: Glycolaldehyde dehydrogenase
product: 705931
reactant: 705907
fast: false
product: 705943
product: 705955
reversible: false

305543
value: 999999.0
type: LocalParameter

303003
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Acetate_C2H3O2
type: Species

303098
product: 695699
reversible: true
notes: Abbreviation: R_ADCL Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 4adcho <==> 4abz + h + pyr Confidence Level: 2 EC: 4.1.3.38 IT genes: LOCUS:BLBBGE_455#ABBREVIATION:ilvE#ECNUMBERS:4.1.3.38# proteins: NAME:Aminodeoxychorismate lyase#ABBREVIATION:IlvE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_455)
type: Reaction
name: _4-aminobenzoate synthase
product: 695687
product: 695675
fast: false
kinetic law: 695711
reactant: 695663

305742
value: 0.0
type: LocalParameter

304176
value: 999999.0
type: LocalParameter

696059
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304023
value: 0.0
type: LocalParameter

305282
value: 0.0
type: LocalParameter

303092
product: 695421
product: 695409
reactant: 695397
fast: false
product: 695433
kinetic law: 695445
notes: Abbreviation: R_ACPS1 Synonyms: _0 EC Number: 2.7.8.7 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : apoACP + coa --> ACP + h + pap Confidence Level: 4 JLR genes: LOCUS:BLBBGE_379#ABBREVIATION:acpT#ECNUMBERS:2.7.8.7# proteins: NAME:holo-(acyl carrier protein) synthase 2#ABBREVIATION:AcpT# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_379)
type: Reaction
reversible: false
reactant: 695384
name: acyl-carrier protein synthase

698522
stoichiometry: 0.276
species: 302679
type: SpeciesReference

710923
stoichiometry: 1.0
species: 302526
type: SpeciesReference

303870
value: 999999.0
type: LocalParameter

699235
stoichiometry: 11.0
species: 302723
type: SpeciesReference

305288
value: 0.0
type: LocalParameter

712584
stoichiometry: 1.0
species: 302562
type: SpeciesReference

305533
value: 999999.0
type: LocalParameter

303013
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: CO2_CO2
type: Species

304312
value: 0.0
type: LocalParameter

696662
stoichiometry: 1.0
species: 302461
type: SpeciesReference

302874
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
type: Species

701563
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304258
value: 0.0
type: LocalParameter

303551
fast: false
name: nucleoside-diphosphate kinase (ATP:UDP)
product: 711361
type: Reaction
reactant: 711336
product: 711349
reversible: true
kinetic law: 711373
notes: Abbreviation: R_NDPK2 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + udp <==> adp + utp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions. genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)
reactant: 711324

305053
value: 999999.0
type: LocalParameter

696396
stoichiometry: 1.0
species: 302659
type: SpeciesReference

710249
stoichiometry: 1.0
species: 302705
type: SpeciesReference

305802
value: 0.0
type: LocalParameter

304470
value: 0.0
type: LocalParameter

704577
stoichiometry: 1.0
species: 303063
type: SpeciesReference

697774
stoichiometry: 1.0
species: 302865
type: SpeciesReference

305532
value: -999999.0
type: LocalParameter

697616
stoichiometry: 1.0
species: 302744
type: SpeciesReference

303550
fast: false
type: Reaction
reactant: 711275
name: nucleoside-diphosphate kinase (ATP:GDP)
kinetic law: 711312
product: 711299
reactant: 711262
reversible: true
notes: Abbreviation: R_NDPK1 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + gdp <==> adp + gtp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions. genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)
product: 711287

303014
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Cysteine_C3H7NO2S
type: Species

305287
value: 999999.0
type: LocalParameter

304257
value: 0.0
type: LocalParameter

713575
stoichiometry: 1.0
species: 302633
type: SpeciesReference

302873
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _1-(5-Phosphoribosyl)-ATP_C15H19N5O20P4
type: Species

713479
stoichiometry: 1.0
species: 302659
type: SpeciesReference

700319
stoichiometry: 1.0
species: 302659
type: SpeciesReference

707148
stoichiometry: 1.0
species: 302659
type: SpeciesReference

695843
stoichiometry: 1.0
species: 302651
type: SpeciesReference

718432
stoichiometry: 1.0
species: 302538
type: SpeciesReference

305054
value: 0.0
type: LocalParameter

303764
fast: false
kinetic law: 719920
reversible: false
product: 719908
name: threonine synthase
product: 719896
notes: Abbreviation: R_THRS Synonyms: _0 EC Number: 4.2.3.1 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : h2o + phom --> pi + thr-L Confidence Level: 2 genes: LOCUS:BLBBGE_499#ABBREVIATION:thrC#ECNUMBERS:4.2.3.1# proteins: NAME:Threonine synthase#ABBREVIATION:ThrC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_499)
reactant: 719884
type: Reaction
reactant: 719872

698594
stoichiometry: 1.3E-4
species: 302723
type: SpeciesReference

305801
value: 0.0
type: LocalParameter

708965
stoichiometry: 1.0
species: 302723
type: SpeciesReference

303763
kinetic law: 719860
product: 719847
product: 719835
reactant: 719823
notes: Abbreviation: R_THRD_L Synonyms: _1 EC Number: 4.3.1.19 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : thr-L --> 2obut + nh4 Confidence Level: 2 Previous EC number: 4.2.1.16. New EC number 4.3.1.19. Can't enter this.... genes: LOCUS:BLBBGE_553#ABBREVIATION:ilvA#ECNUMBERS:4.3.1.19# proteins: NAME:threonine deaminase#ABBREVIATION:IlvA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_553)
fast: false
reversible: false
name: L-threonine deaminase
type: Reaction

704602
stoichiometry: 1.0
species: 302919
type: SpeciesReference

303094
fast: false
name: Adenosine deaminase
reactant: 695519
notes: Abbreviation: R_ADA Synonyms: _0 EC Number: 3.5.4.4 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : adn + h + h2o --> ins + nh4 Confidence Level: 1 Added EC- JLR genes: none proteins: none citations: none GENE ASSOCIATION:
type: Reaction
reactant: 695531
product: 695555
product: 695567
reversible: false
kinetic law: 695579
reactant: 695543

304310
value: 999999.0
type: LocalParameter

711481
stoichiometry: 1.0
species: 302585
type: SpeciesReference

302945
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Thymidine_C10H14N2O5
type: Species

695531
stoichiometry: 1.0
species: 302659
type: SpeciesReference

703195
stoichiometry: 1.0
species: 303003
type: SpeciesReference

305051
value: 0.0
type: LocalParameter

305535
value: 0.0
type: LocalParameter

305209
value: 999999.0
type: LocalParameter

304821
value: 999999.0
type: LocalParameter

305800
value: 0.0
type: LocalParameter

303989
value: 0.0
type: LocalParameter

303762
product: 719762
type: Reaction
product: 719774
kinetic law: 719811
reactant: 719738
product: 719786
reactant: 719726
fast: false
reversible: false
name: L-threonine transport via ABC system
product: 719799
notes: Abbreviation: R_THRabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + thr-L[e] --> adp[c] + h[c] + pi[c] + thr-L[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 719750

711542
stoichiometry: 1.0
species: 302565
type: SpeciesReference

303093
reactant: 695458
type: Reaction
notes: Abbreviation: R_ACt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: ac[e] + h[e] <==> ac[c] + h[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
reversible: true
reactant: 695470
fast: false
name: acetate reversible transport via proton symport
product: 695482
product: 695494
kinetic law: 695506

304311
value: 0.0
type: LocalParameter

302944
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Thymine_C5H6N2O2
type: Species

305285
value: -999999.0
type: LocalParameter

305534
value: 0.0
type: LocalParameter

702337
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304822
value: 0.0
type: LocalParameter

695494
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304259
value: 0.0
type: LocalParameter

704309
stoichiometry: 1.0
species: 302734
type: SpeciesReference

709315
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303988
value: 999999.0
type: LocalParameter

304254
value: 0.0
type: LocalParameter

303162
reactant: 698763
reactant: 698281
reactant: 698317
reactant: 698341
reactant: 698522
reactant: 698413
product: 698787
reactant: 698667
reactant: 698485
type: Reaction
reactant: 698691
reactant: 698437
reactant: 698606
reactant: 698703
reversible: false
reactant: 698727
reactant: 698534
reactant: 698558
reactant: 698329
reactant: 698643
reactant: 698461
kinetic law: 698836
reactant: 698582
reactant: 698679
reactant: 698497
name: BiomassBge
reactant: 698353
reactant: 698305
reactant: 698377
reactant: 698631
reactant: 698449
reactant: 698389
reactant: 698655
reactant: 698473
reactant: 698715
reactant: 698293
reactant: 698509
reactant: 698775
reactant: 698570
fast: false
reactant: 698594
reactant: 698401
product: 698800
reactant: 698365
product: 698824
reactant: 698619
reactant: 698425
product: 698812
reactant: 698546
notes: Abbreviation: R_BiomassBge Equation: [c] : (0.488) ala-L + (0.001) amp + (0.281) arg-L + (0.229) asn-L + (0.229) asp-L + (45.7318) atp + (0.000006) coa + (0.126) ctp + (0.087) cys-L + (0.0365) datp + (0.0135) dctp + (0.0135) dgtp + (0.0365) dttp + (0.00001) fad + (0.25) gln-L + (0.25) glu-L + (0.582) gly + (0.203) gtp + (45.5608) h2o + (0.09) his-L + (0.276) ile-L + (0.428) leu-L + (0.326) lys-L + (0.146) met-L + (0.00215) nad + (0.00005) nadh + (0.00013) nadp + (0.0004) nadph + (0.001935) pe_Bge + (0.0276) peptido_Bge + (0.176) phe-L + (0.21) pro-L + (0.000052) ps_Bge + (0.035) ptrc + (0.205) ser-L + (0.000223) thf + (0.000223) thmpp[c] + (0.241) thr-L + (0.054) trp-L + (0.131) tyr-L + (0.136) utp + (0.402) val-L --> (45.5608) adp + (45.56035) h + (45.5628) pi + (0.7302) ppi Confidence Level: genes: none proteins: none citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION:
reactant: 698739
reactant: 698751

304170
value: 0.0
type: LocalParameter

303341
kinetic law: 704443
product: 704430
reactant: 704417
notes: Abbreviation: R_EX_pnto_R_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : pnto-R <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: (R)-Pantothenate exchange
type: Reaction

708140
stoichiometry: 1.0
species: 302595
type: SpeciesReference

697360
stoichiometry: 1.0
species: 302464
type: SpeciesReference

697286
stoichiometry: 1.0
species: 302628
type: SpeciesReference

303769
reversible: false
name: thiamine diphosphokinase
type: Reaction
reactant: 720126
product: 720150
product: 720174
product: 720162
notes: Abbreviation: R_TMDPK Synonyms: _0 EC Number: 2.7.6.2 SUBSYSTEM: Thiamine Metabolism Equation: [c] : atp + thm --> amp + h + thmpp Confidence Level: 2 genes: LOCUS:BLBBGE_618#ABBREVIATION:thiN#ECNUMBERS:2.7.6.2# proteins: NAME:thiamin pyrophosphokinase 1#ABBREVIATION:ThiN# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_618)
fast: false
reactant: 720138
kinetic law: 720186

302523
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Aspartate_C4H6NO4
type: Species

707798
stoichiometry: 1.0
species: 302768
type: SpeciesReference

303801
kinetic law: 721889
product: 721877
product: 721865
reactant: 721853
notes: Abbreviation: R_UPP3S Synonyms: _0 EC Number: 4.2.1.75 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : hmbil --> h2o + uppg3 Confidence Level: 2 genes: LOCUS:BLBBGE_290#ABBREVIATION:hemD#ECNUMBERS:4.2.1.75# LOCUS:BLBBGE_576#ABBREVIATION:hemD#ECNUMBERS:4.2.1.75# proteins: NAME:Uroporphyrinogen III synthase#ABBREVIATION:HemD# NAME:Uroporphyrinogen III synthase#ABBREVIATION:HemD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_290) or (BLBBGE_576)
fast: false
reversible: false
name: uroporphyrinogen-III synthase
type: Reaction

305207
value: 0.0
type: LocalParameter

304316
value: 999999.0
type: LocalParameter

302870
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _1-(5-Phosphoribosyl)-AMP_C15H19N5O14P2
type: Species

303555
reversible: true
type: Reaction
product: 711469
product: 711481
name: nucleoside-diphosphate kinase (ATP:dTDP)
notes: Abbreviation: R_NDPK4 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dtdp <==> adp + dttp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions. genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)
reactant: 711445
reactant: 711457
fast: false
kinetic law: 711493

305537
value: 999999.0
type: LocalParameter

304171
value: -999999.0
type: LocalParameter

303010
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Aspartate_C4H6NO4
type: Species

303554
product: 711421
type: Reaction
product: 711409
name: nucleoside-diphosphate kinase (ATP:CDP)
reversible: true
fast: false
reactant: 711397
kinetic law: 711433
reactant: 711385
notes: Abbreviation: R_NDPK3 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + cdp <==> adp + ctp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)

700079
stoichiometry: 1.0
species: 302659
type: SpeciesReference

719992
stoichiometry: 1.0
species: 302593
type: SpeciesReference

697214
stoichiometry: 1.0
species: 302512
type: SpeciesReference

303802
kinetic law: 721961
product: 721937
reactant: 721901
fast: false
notes: Abbreviation: R_UREA Synonyms: _0 EC Number: 3.5.1.5 Equation: [c] : (2) h + h2o + urea --> co2 + (2) nh4 Confidence Level: 4 genes: LOCUS:BLBBGE_502#ABBREVIATION:ureAB#ECNUMBERS:3.5.1.5# LOCUS:BLBBGE_503#ABBREVIATION:ureC#ECNUMBERS:3.5.1.5# proteins: NAME:Urease, alpha subunit#ABBREVIATION:UreC# NAME:Urease beta gamma subunit#ABBREVIATION:UreAB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_502) and (BLBBGE_503)
reactant: 721913
name: urease
product: 721949
type: Reaction
reversible: false
reactant: 721925

715189
stoichiometry: 1.0
species: 302655
type: SpeciesReference

707365
stoichiometry: 1.0
species: 302666
type: SpeciesReference

302522
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Aspartate_C4H6NO4
type: Species

303768
product: 720078
reactant: 720054
reactant: 720066
fast: false
type: Reaction
notes: Abbreviation: R_TMDK1 Synonyms: _0 EC Number: 2.7.1.21 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + thymd --> adp + dtmp + h Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 720102
product: 720090
reversible: false
name: thymidine kinase (ATP:thymidine)
kinetic law: 720114

303667
kinetic law: 715117
product: 715093
reactant: 715057
name: pantothenate kinase
notes: Abbreviation: R_PNTK Synonyms: _0 EC Number: 2.7.1.33 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + pnto-R --> 4ppan + adp + h Confidence Level: 2 genes: LOCUS:BLBBGE_132#ABBREVIATION:coaA#ECNUMBERS:2.7.1.33# proteins: NAME:pantothenate kinase#ABBREVIATION:CoaA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_132)
product: 715081
fast: false
reversible: false
type: Reaction
product: 715105
reactant: 715069

710466
stoichiometry: 1.0
species: 302475
type: SpeciesReference

304317
value: 0.0
type: LocalParameter

305208
value: 0.0
type: LocalParameter

304659
value: 999999.0
type: LocalParameter

305536
value: -999999.0
type: LocalParameter

304256
value: 999999.0
type: LocalParameter

712364
stoichiometry: 1.0
species: 302546
type: SpeciesReference

699343
stoichiometry: 7.0
species: 302655
type: SpeciesReference

303160
kinetic law: 698183
type: Reaction
fast: false
reversible: false
name: ATP phosphoribosyltransferase
product: 698169
notes: Abbreviation: R_ATPPRT Synonyms: _0 EC Number: 2.4.2.17 SUBSYSTEM: Histidine Metabolism Equation: [c] : atp + prpp --> ppi + prbatp Confidence Level: 2 genes: LOCUS:BLBBGE_433#ABBREVIATION:hisG#ECNUMBERS:2.4.2.17# proteins: NAME:ATP phosphoribosyltransferase#ABBREVIATION:HisG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_433)
product: 698156
reactant: 698130
reactant: 698143

302949
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Reduced thioredoxin_XH2
type: Species

302521
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Asparagine_C4H8N2O3
type: Species

709996
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304019
value: 0.0
type: LocalParameter

703449
stoichiometry: 1.0
species: 303014
type: SpeciesReference

303767
name: transketolase
fast: false
product: 720017
kinetic law: 720042
reversible: true
reactant: 720005
notes: Abbreviation: R_TKT2 Synonyms: _0 EC Number: 2.2.1.1 SUBSYSTEM: Pentose Phosphate Pathway Equation: [c] : e4p + xu5p-D <==> f6p + g3p Confidence Level: 2 SMP Two reactions for transketolase: TKT1 and TKT2 genes: LOCUS:BLBBGE_403#ABBREVIATION:tkt#ECNUMBERS:2.2.1.1# LOCUS:BLBBGE_404#ABBREVIATION:tkt#ECNUMBERS:2.2.1.1# proteins: NAME:transketolase N-terminal subunit#ABBREVIATION:Tkt# NAME:transketolase C-terminal subunit#ABBREVIATION:Tkt# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_403 and BLBBGE_404)
type: Reaction
reactant: 719992
product: 720029

711759
stoichiometry: 1.0
species: 302678
type: SpeciesReference

722251
stoichiometry: 1.0
species: 302993
type: SpeciesReference

304658
value: 0.0
type: LocalParameter

715515
stoichiometry: 1.0
species: 302719
type: SpeciesReference

303666
product: 715033
reactant: 715009
product: 715021
notes: Abbreviation: R_PMEVKx Synonyms: _0 EC Number: 2.7.4.2 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : 5pmev + atp --> 5dpmev + adp Confidence Level: 2 genes: LOCUS:BLBBGE_085#ABBREVIATION:mvaK#ECNUMBERS:2.7.4.2# proteins: NAME:phosphomevalonate kinase#ABBREVIATION:mvaK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_085)
type: Reaction
name: phosphomevalonate kinase
kinetic law: 715045
reversible: false
reactant: 714997
fast: false

303908
value: 999999.0
type: LocalParameter

305205
value: 999999.0
type: LocalParameter

304314
value: 0.0
type: LocalParameter

716971
stoichiometry: 1.0
species: 302853
type: SpeciesReference

305539
value: 0.0
type: LocalParameter

701890
stoichiometry: 1.0
species: 302569
type: SpeciesReference

704680
stoichiometry: 1.0
species: 302938
type: SpeciesReference

707969
stoichiometry: 1.0
species: 302500
type: SpeciesReference

699079
stoichiometry: 5.0
species: 302487
type: SpeciesReference

705287
stoichiometry: 1.0
species: 302609
type: SpeciesReference

703111
stoichiometry: 1.0
species: 302720
type: SpeciesReference

303161
type: Reaction
product: 698245
reactant: 698209
reversible: true
product: 698257
fast: false
kinetic law: 698269
product: 698233
notes: Abbreviation: R_ATPS4r Synonyms: _0 EC Number: 3.6.3.14 SUBSYSTEM: Oxidative Phosphorylation Equation: adp[c] + (4) h[e] + pi[c] <==> atp[c] + (3) h[c] + h2o[c] Confidence Level: 2 JLR- added reversible form of ATPS4 reactioin genes: LOCUS:BLBBGE_074#ABBREVIATION:atpC#ECNUMBERS:3.6.3.14# LOCUS:BLBBGE_073#ABBREVIATION:atpD#ECNUMBERS:3.6.3.14# LOCUS:BLBBGE_562#ABBREVIATION:atpG#ECNUMBERS:3.6.3.14# LOCUS:BLBBGE_563#ABBREVIATION:atpA#ECNUMBERS:3.6.3.14# LOCUS:BLBBGE_564#ABBREVIATION:atpH#ECNUMBERS:3.6.3.14# LOCUS:BLBBGE_565#ABBREVIATION:atpF#ECNUMBERS:3.6.3.14# LOCUS:BLBBGE_566#ABBREVIATION:atpE#ECNUMBERS:3.6.3.14# LOCUS:BLBBGE_567#ABBREVIATION:atpB#ECNUMBERS:3.6.3.14# proteins: NAME:ATP synthase F1#ABBREVIATION:AtpF1# NAME:ATP synthase F0#ABBREVIATION:AtpF0# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_566 and BLBBGE_565 and BLBBGE_567) and (BLBBGE_564 and BLBBGE_563 and BLBBGE_562 and BLBBGE_073 and BLBBGE_074)
name: ATP synthase (four protons for one ATP)
reactant: 698221
reactant: 698196

302948
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Oxidized thioredoxin_X
type: Species

705409
stoichiometry: 1.0
species: 302853
type: SpeciesReference

721476
stoichiometry: 1.0
species: 302970
type: SpeciesReference

303766
notes: Abbreviation: R_TKT1 Synonyms: _0 EC Number: 2.2.1.1 SUBSYSTEM: Pentose Phosphate Pathway Equation: [c] : r5p + xu5p-D <==> g3p + s7p Confidence Level: 2 SMP Two reactions for transketolase: TKT1 and TKT2 genes: LOCUS:BLBBGE_403#ABBREVIATION:tkt#ECNUMBERS:2.2.1.1# LOCUS:BLBBGE_404#ABBREVIATION:tkt#ECNUMBERS:2.2.1.1# proteins: NAME:transketolase N-terminal subunit#ABBREVIATION:Tkt# NAME:transketolase C-terminal subunit#ABBREVIATION:Tkt# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_403 and BLBBGE_404)
product: 719968
name: transketolase
kinetic law: 719980
reversible: true
reactant: 719944
type: Reaction
product: 719956
reactant: 719932
fast: false

701817
stoichiometry: 1.0
species: 302575
type: SpeciesReference

304657
value: 0.0
type: LocalParameter

305538
value: 0.0
type: LocalParameter

303909
value: 0.0
type: LocalParameter

305206
value: 0.0
type: LocalParameter

715033
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304932
value: 0.0
type: LocalParameter

305316
value: 0.0
type: LocalParameter

305428
value: 0.0
type: LocalParameter

303559
fast: false
name: nucleoside-diphosphate kinase (ATP:dUDP)
kinetic law: 711614
notes: Abbreviation: R_NDPK6 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dudp <==> adp + dutp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions. genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)
reactant: 711566
product: 711590
reactant: 711578
reversible: true
product: 711602
type: Reaction

304656
value: 0.0
type: LocalParameter

304503
value: -999999.0
type: LocalParameter

302499
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-amino-1-(5-phospho-D-ribosyl)imidazole_C8H12N3O7P
type: Species

303878
value: 0.0
type: LocalParameter

707689
stoichiometry: 1.0
species: 302659
type: SpeciesReference

720102
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302632
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Glutamate_C5H8NO4
type: Species

720078
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304250
value: 999999.0
type: LocalParameter

712097
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303166
type: Reaction
reactant: 698909
product: 698957
reactant: 698945
fast: false
reversible: false
product: 698970
name: Fatty acid biosynthesis (n-C12:0)
product: 698982
reactant: 698933
product: 699007
product: 698994
reactant: 698921
notes: Abbreviation: R_C120SN Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : actACP + (14) h + (4) malACP + (10) nadph --> (4) ACP + (4) co2 + ddcaACP + (5) h2o + (10) nadp Confidence Level: 2 TV, JRNeidhard pg. 615 genes: LOCUS:BLBBGE_037#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-# LOCUS:BLBBGE_346#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9# LOCUS:BLBBGE_057#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100# LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.179# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabG# NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI# NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_037) and (BLBBGE_079) and (BLBBGE_346) and (BLBBGE_057)
kinetic law: 699019

718058
stoichiometry: 1.0
species: 302898
type: SpeciesReference

303450
name: homoserine dehydrogenase (NADPH)
fast: false
notes: Abbreviation: R_HSDy Synonyms: _0 EC Number: 1.1.1.3 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : aspsa + h + nadph --> hom-L + nadp Confidence Level: 2 genes: LOCUS:BLBBGE_501#ABBREVIATION:thrA#ECNUMBERS:2.7.2.4,-!-,1.1.1.3# proteins: NAME:Homoserine dehydrogenase#ABBREVIATION:MetL# NAME:Aspartate kinase I#ABBREVIATION:ThrA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_501)
product: 707725
reactant: 707677
reactant: 707689
type: Reaction
reversible: false
reactant: 707701
product: 707713
kinetic law: 707737

304933
value: 999999.0
type: LocalParameter

303558
notes: Abbreviation: R_NDPK5 Synonyms: _0 EC Number: 2.7.4.6 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dgdp <==> adp + dgtp Confidence Level: 2 Many nucleoside diphosphates (eight described) can act as acceptors. While many ribo- and deoxyribonucleoside triphosphates can act as donors, only ATP is chosen as a donor to minimize the number of total reactions. genes: LOCUS:BLBBGE_453#ABBREVIATION:ndk#ECNUMBERS:2.7.4.6# proteins: NAME:nucleoside diphosphate kinase#ABBREVIATION:Ndk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_453)
product: 711542
kinetic law: 711554
product: 711530
reactant: 711518
name: nucleoside-diphosphate kinase (ATP:dGDP)
reversible: true
type: Reaction
reactant: 711505
fast: false

MODEL1110130000
species: 302769
reaction: 303302
species: 303061
species: 302975
reaction: 303550
species: 302883
species: 302691
species: 302438
reaction: 303639
species: 302748
species: 302648
reaction: 303462
species: 302556
species: 302958
reaction: 303729
species: 302674
species: 302984
species: 302705
species: 303023
reaction: 303467
species: 302513
reaction: 303281
reaction: 303791
species: 302421
reaction: 303358
reaction: 303313
reaction: 303715
reaction: 303566
species: 302765
reaction: 303700
species: 302610
species: 302920
reaction: 303801
species: 302485
reaction: 303421
reaction: 303674
reaction: 303097
species: 302644
species: 303040
species: 302954
reaction: 303502
reaction: 303459
species: 302670
species: 302468
reaction: 303783
reaction: 303499
species: 302980
species: 302701
reaction: 303305
reaction: 303471
species: 302539
reaction: 303114
reaction: 303651
species: 302447
reaction: 303570
reaction: 303190
species: 302565
species: 302875
reaction: 303369
reaction: 303083
reaction: 303558
species: 302714
species: 303032
species: 302548
reaction: 303776
species: 303066
reaction: 303274
reaction: 303104
species: 302464
species: 303015
species: 302929
species: 302696
reaction: 303289
reaction: 303694
reaction: 303799
species: 302753
species: 302679
reaction: 303094
reaction: 303314
species: 302561

305317
value: 0.0
type: LocalParameter

303806
product: 722094
product: 722118
name: uridine kinase (GTP:Uridine)
kinetic law: 722130
notes: Abbreviation: R_URIK2 Synonyms: _0 EC Number: 2.7.1.48 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : gtp + uri --> gdp + h + ump Confidence Level: 2 genes: LOCUS:BLBBGE_535#ABBREVIATION:udk#ECNUMBERS:2.7.1.48# proteins: NAME:uridine/cytidine kinase#ABBREVIATION:Udk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_535)
reactant: 722082
type: Reaction
fast: false
reversible: false
reactant: 722070
product: 722106

304655
value: 999999.0
type: LocalParameter

304502
value: 0.0
type: LocalParameter

305427
value: 999999.0
type: LocalParameter

303877
value: 0.0
type: LocalParameter

703339
stoichiometry: 1.0
species: 303009
type: SpeciesReference

707256
stoichiometry: 1.0
species: 302655
type: SpeciesReference

722046
stoichiometry: 1.0
species: 302587
type: SpeciesReference

305640
value: 999999.0
type: LocalParameter

304478
value: 999999.0
type: LocalParameter

303167
reactant: 699043
product: 699127
name: Fatty acid biosynthesis (n-C14:0)
reactant: 699055
fast: false
product: 699103
reversible: false
reactant: 699031
kinetic law: 699139
type: Reaction
product: 699091
product: 699079
reactant: 699067
product: 699115
notes: Abbreviation: R_C140SN Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : actACP + (17) h + (5) malACP + (12) nadph --> (5) ACP + (5) co2 + (6) h2o + myrsACP + (12) nadp Confidence Level: 2 tvNeidhardt genes: LOCUS:BLBBGE_037#ABBREVIATION:fabZ#ECNUMBERS:4.2.1.-# LOCUS:BLBBGE_346#ABBREVIATION:fabI#ECNUMBERS:1.3.1.9# LOCUS:BLBBGE_057#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100# LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.179# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabG# NAME:Enoyl-(acyl-carrier-protein) reductase (NADH)#ABBREVIATION:FabI# NAME:(3R)-hydroxymyriostoyl-(acyl carrier protein) dehydratase#ABBREVIATION:FabZ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_037) and (BLBBGE_079) and (BLBBGE_346) and (BLBBGE_057)

713744
stoichiometry: 1.0
species: 302536
type: SpeciesReference

703087
stoichiometry: 1.0
species: 302456
type: SpeciesReference

303663
product: 714973
name: pyrimidine phosphatase
fast: false
type: Reaction
kinetic law: 714985
notes: Abbreviation: R_PMDPHT Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 5aprbu + h2o --> 4r5au + pi Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 714961
reactant: 714949
reversible: false
reactant: 714937

304934
value: 0.0
type: LocalParameter

304501
value: 0.0
type: LocalParameter

304318
value: 0.0
type: LocalParameter

701927
stoichiometry: 1.0
species: 302536
type: SpeciesReference

718661
stoichiometry: 1.0
species: 302724
type: SpeciesReference

708212
stoichiometry: 1.0
species: 302442
type: SpeciesReference

711602
stoichiometry: 1.0
species: 302591
type: SpeciesReference

303803
kinetic law: 721997
product: 721985
reactant: 721973
notes: Abbreviation: R_UREAt Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: urea[e] <==> urea[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_460#ABBREVIATION:glpF# proteins: NAME:MIP channel, glycerol diffusion#ABBREVIATION:GlpF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_460)
fast: false
reversible: true
name: Urea transport via facilitate diffusion
type: Reaction

702603
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303876
value: 999999.0
type: LocalParameter

705057
stoichiometry: 1.0
species: 302526
type: SpeciesReference

717419
stoichiometry: 1.0
species: 302655
type: SpeciesReference

699187
stoichiometry: 11.0
species: 302724
type: SpeciesReference

302630
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Glutamate 5-semialdehyde_C5H9NO3
type: Species

305314
value: 999999.0
type: LocalParameter

305399
value: 0.0
type: LocalParameter

303662
type: Reaction
product: 714913
reactant: 714889
reversible: true
fast: false
notes: Abbreviation: R_PIt7 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: (3) na1[e] + pi[e] <==> (3) na1[c] + pi[c] Confidence Level: 2 NCD genes: LOCUS:BLBBGE_368#ABBREVIATION:pit# proteins: NAME:phosphate sodium symporter#ABBREVIATION:Pit# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_368)
kinetic law: 714925
product: 714901
reactant: 714877
name: phosphate transport in/out via three Na+ symporter

304654
value: -999999.0
type: LocalParameter

304252
value: 0.0
type: LocalParameter

711275
stoichiometry: 1.0
species: 302626
type: SpeciesReference

714853
stoichiometry: 1.0
species: 302769
type: SpeciesReference

722143
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304935
value: 0.0
type: LocalParameter

304319
value: -999999.0
type: LocalParameter

305315
value: 0.0
type: LocalParameter

305429
value: 0.0
type: LocalParameter

694754
stoichiometry: 1.0
species: 302770
type: SpeciesReference

303804
reactant: 722022
notes: Abbreviation: R_URIDK2r Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dump <==> adp + dudp Confidence Level: 2 JLR- reversible form of URIDK2 genes: LOCUS:BLBBGE_120#ABBREVIATION:pyrH#ECNUMBERS:2.7.4.-# proteins: NAME:uridylate kinase#ABBREVIATION:PyrH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_120)
fast: false
reversible: true
reactant: 722009
name: uridylate kinase (dUMP)
product: 722046
kinetic law: 722058
type: Reaction
product: 722034

712849
stoichiometry: 1.0
species: 302557
type: SpeciesReference

721585
stoichiometry: 8.0
species: 302687
type: SpeciesReference

709521
stoichiometry: 1.0
species: 302500
type: SpeciesReference

303165
fast: false
reactant: 698848
kinetic law: 698897
notes: Abbreviation: R_BPNT Synonyms: _0 EC Number: 3.1.3.7 SUBSYSTEM: Cysteine Metabolism Equation: [c] : h2o + pap --> amp + pi Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 698885
product: 698872
reactant: 698860
reversible: false
type: Reaction
name: _3',5'-bisphosphate nucleotidase

701781
stoichiometry: 1.0
species: 302934
type: SpeciesReference

304500
value: 999999.0
type: LocalParameter

304251
value: 0.0
type: LocalParameter

304476
value: -999999.0
type: LocalParameter

304653
value: 0.0
type: LocalParameter

303874
value: -999999.0
type: LocalParameter

697882
stoichiometry: 1.0
species: 302521
type: SpeciesReference

302418
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (S)-2-Aceto-2-hydroxybutanoate_C6H9O4
type: Species

716489
stoichiometry: 1.0
species: 302853
type: SpeciesReference

713926
stoichiometry: 1.0
species: 302536
type: SpeciesReference

709678
stoichiometry: 2.0
species: 302659
type: SpeciesReference

700427
stoichiometry: 1.0
species: 302544
type: SpeciesReference

695384
stoichiometry: 1.0
species: 302513
type: SpeciesReference

695999
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304936
value: -999999.0
type: LocalParameter

304710
value: 0.0
type: LocalParameter

698233
stoichiometry: 1.0
species: 302526
type: SpeciesReference

714961
stoichiometry: 1.0
species: 302460
type: SpeciesReference

703800
stoichiometry: 1.0
species: 302644
type: SpeciesReference

305397
value: 0.0
type: LocalParameter

304652
value: 0.0
type: LocalParameter

701672
stoichiometry: 1.0
species: 302893
type: SpeciesReference

304473
value: 0.0
type: LocalParameter

302943
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Threonine_C4H9NO3
type: Species

698679
stoichiometry: 0.035
species: 302885
type: SpeciesReference

718917
stoichiometry: 1.0
species: 302526
type: SpeciesReference

302495
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: S-Adenosyl-L-homocysteine_C14H20N6O5S
type: Species

303761
product: 719690
kinetic law: 719714
product: 719677
product: 719702
notes: Abbreviation: R_THMabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + thm[e] --> adp[c] + h[c] + pi[c] + thm[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reversible: false
name: thiamine transport via ABC system
reactant: 719653
type: Reaction
product: 719665
reactant: 719629
fast: false
reactant: 719641

710814
stoichiometry: 2.8
species: 302660
type: SpeciesReference

718541
stoichiometry: 1.0
species: 302893
type: SpeciesReference

717853
stoichiometry: 1.0
species: 302948
type: SpeciesReference

709886
stoichiometry: 1.0
species: 302724
type: SpeciesReference

708856
stoichiometry: 1.0
species: 302659
type: SpeciesReference

714131
stoichiometry: 0.04
species: 302712
type: SpeciesReference

302417
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: meso-2,6-Diaminoheptanedioate_C7H14N2O4
type: Species

304506
value: 0.0
type: LocalParameter

304937
value: 999999.0
type: LocalParameter

304711
value: 999999.0
type: LocalParameter

712437
stoichiometry: 1.0
species: 302945
type: SpeciesReference

304651
value: 999999.0
type: LocalParameter

305396
value: 999999.0
type: LocalParameter

695421
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305423
value: 0.0
type: LocalParameter

304474
value: 0.0
type: LocalParameter

713684
stoichiometry: 1.0
species: 302659
type: SpeciesReference

696772
stoichiometry: 1.0
species: 302502
type: SpeciesReference

704249
stoichiometry: 1.0
species: 303050
type: SpeciesReference

699451
stoichiometry: 6.0
species: 302536
type: SpeciesReference

697725
stoichiometry: 1.0
species: 302533
type: SpeciesReference

302416
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: LL-2,6-Diaminoheptanedioate_C7H14N2O4
type: Species

304938
value: 0.0
type: LocalParameter

695783
stoichiometry: 1.0
species: 302511
type: SpeciesReference

304712
value: 0.0
type: LocalParameter

305426
value: 0.0
type: LocalParameter

305318
value: 999999.0
type: LocalParameter

304505
value: 0.0
type: LocalParameter

303807
product: 722179
product: 722215
type: Reaction
reactant: 722155
reactant: 722143
product: 722191
notes: Abbreviation: R_VALabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + val-L[e] --> adp[c] + h[c] + pi[c] + val-L[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
kinetic law: 722227
reversible: false
name: L-valine transport via ABC system
reactant: 722167
product: 722203

710574
stoichiometry: 2.0
species: 302659
type: SpeciesReference

304471
value: 0.0
type: LocalParameter

304650
value: -999999.0
type: LocalParameter

302497
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate_C9H12N5O13P3
type: Species

719050
stoichiometry: 2.0
species: 302660
type: SpeciesReference

303872
value: 0.0
type: LocalParameter

702711
stoichiometry: 1.0
species: 302526
type: SpeciesReference

719774
stoichiometry: 1.0
species: 302659
type: SpeciesReference

713890
stoichiometry: 1.0
species: 302500
type: SpeciesReference

302415
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2,5-Diamino-6-(ribosylamino)-4-(3H)-pyrimidinone 5'-phosphate_C9H14N5O8P
type: Species

699127
stoichiometry: 12.0
species: 302723
type: SpeciesReference

304939
value: 0.0
type: LocalParameter

305425
value: 0.0
type: LocalParameter

304504
value: 999999.0
type: LocalParameter

305319
value: 0.0
type: LocalParameter

709739
stoichiometry: 1.0
species: 302538
type: SpeciesReference

700607
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304713
value: 0.0
type: LocalParameter

303808
reversible: true
reactant: 722251
reactant: 722239
notes: Abbreviation: R_VALTA Synonyms: _0 EC Number: 2.6.1.42 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : akg + val-L <==> 3mob + glu-L Confidence Level: 2 genes: LOCUS:BLBBGE_455#ABBREVIATION:ilvE#ECNUMBERS:2.6.1.42,-!-,2.6.1.2# proteins: NAME:Branched-chain-amino-acid aminotransferase#ABBREVIATION:IlvE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_455)
product: 722275
type: Reaction
product: 722263
fast: false
name: valine transaminase
kinetic law: 722287

700559
stoichiometry: 1.0
species: 302710
type: SpeciesReference

304472
value: 999999.0
type: LocalParameter

700982
stoichiometry: 1.0
species: 302417
type: SpeciesReference

302940
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Threonine_C4H9NO3
type: Species

696312
stoichiometry: 1.0
species: 302885
type: SpeciesReference

303871
value: 0.0
type: LocalParameter

305394
value: 0.0
type: LocalParameter

302498
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide_C9H13N4O8P
type: Species

697433
stoichiometry: 1.0
species: 302517
type: SpeciesReference

710706
stoichiometry: 1.0
species: 302720
type: SpeciesReference

303431
name: GTP cyclohydrolase II (25drapp)
kinetic law: 707124
notes: Abbreviation: R_GTPCII2 Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : gtp + (3) h2o --> 25drapp + for + (2) h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_323#ABBREVIATION:ribBA#ECNUMBERS:3.5.4.25,-!-,4.1.99.12# proteins: NAME:_bifunctional 3,4 dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II#ABBREVIATION:RibBA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_323)
reversible: false
product: 707075
product: 707099
product: 707112
fast: false
product: 707087
reactant: 707063
reactant: 707051
type: Reaction

706642
stoichiometry: 1.0
species: 302659
type: SpeciesReference

711044
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302730
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: NMN_C11H14N2O8P
type: Species

705823
stoichiometry: 1.0
species: 302407
type: SpeciesReference

304032
value: 0.0
type: LocalParameter

720258
stoichiometry: 1.0
species: 302588
type: SpeciesReference

702687
stoichiometry: 1.0
species: 302853
type: SpeciesReference

696808
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305759
value: 999999.0
type: LocalParameter

702120
stoichiometry: 1.0
species: 302415
type: SpeciesReference

302423
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Demethylmenaquinol 8_C50H72O2
type: Species

302649
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Geranyl diphosphate_C10H17O7P2
type: Species

305646
value: 0.0
type: LocalParameter

721355
stoichiometry: 1.0
species: 302970
type: SpeciesReference

304705
value: 0.0
type: LocalParameter

711117
stoichiometry: 1.0
species: 302717
type: SpeciesReference

694960
stoichiometry: 1.0
species: 302479
type: SpeciesReference

303326
kinetic law: 704188
product: 704176
reactant: 704163
notes: Abbreviation: R_EX_met_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : met-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Methionine exchange
type: Reaction

304783
value: -999999.0
type: LocalParameter

305422
value: 999999.0
type: LocalParameter

304670
value: 0.0
type: LocalParameter

712644
stoichiometry: 1.0
species: 302648
type: SpeciesReference

706703
stoichiometry: 1.0
species: 302526
type: SpeciesReference

715863
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304031
value: 0.0
type: LocalParameter

718758
stoichiometry: 1.0
species: 302909
type: SpeciesReference

694814
stoichiometry: 1.0
species: 302526
type: SpeciesReference

305758
value: 0.0
type: LocalParameter

305645
value: 999999.0
type: LocalParameter

304704
value: 0.0
type: LocalParameter

303148
product: 697774
product: 697749
type: Reaction
fast: false
name: argininosuccinate synthase
reactant: 697701
kinetic law: 697786
product: 697737
notes: Abbreviation: R_ARGSS Synonyms: _0 EC Number: 6.3.4.5 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : asp-L + atp + citr-L --> amp + argsuc + h + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_313#ABBREVIATION:argG#ECNUMBERS:6.3.4.5# proteins: NAME:argininosuccinate synthetase#ABBREVIATION:ArgG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_313)
product: 697761
reactant: 697725
reversible: false
reactant: 697713

304671
value: 0.0
type: LocalParameter

695056
stoichiometry: 1.0
species: 302893
type: SpeciesReference

705751
stoichiometry: 1.0
species: 302719
type: SpeciesReference

721985
stoichiometry: 1.0
species: 302985
type: SpeciesReference

304034
value: 999999.0
type: LocalParameter

707509
stoichiometry: 1.0
species: 302670
type: SpeciesReference

305648
value: 0.0
type: LocalParameter

714408
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302425
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Deoxy-D-ribose 1-phosphate_C5H9O7P
type: Species

706015
stoichiometry: 1.0
species: 302633
type: SpeciesReference

304703
value: 999999.0
type: LocalParameter

302733
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: O2_O2
type: Species

304672
value: 0.0
type: LocalParameter

305420
value: -999999.0
type: LocalParameter

718130
stoichiometry: 1.0
species: 302918
type: SpeciesReference

720823
stoichiometry: 1.0
species: 302954
type: SpeciesReference

304785
value: 999999.0
type: LocalParameter

699548
stoichiometry: 15.0
species: 302724
type: SpeciesReference

304033
value: 0.0
type: LocalParameter

710189
stoichiometry: 1.0
species: 302493
type: SpeciesReference

709752
stoichiometry: 1.0
species: 302697
type: SpeciesReference

302426
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Isopropylmaleate_C7H8O4
type: Species

305647
value: 0.0
type: LocalParameter

714529
stoichiometry: 1.0
species: 302743
type: SpeciesReference

704949
stoichiometry: 1.0
species: 302596
type: SpeciesReference

303434
reactant: 707136
reactant: 707160
kinetic law: 707196
product: 707172
product: 707184
name: guanine deaminase
type: Reaction
notes: Abbreviation: R_GUAD Synonyms: _0 EC Number: 3.5.4.3 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : gua + h + h2o --> nh4 + xan Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 707148
fast: false
reversible: false

719533
stoichiometry: 1.0
species: 302597
type: SpeciesReference

303329
kinetic law: 704225
product: 704213
reactant: 704200
notes: Abbreviation: R_EX_na1_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : na1 <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Sodium exchange
type: Reaction

710032
stoichiometry: 1.0
species: 302655
type: SpeciesReference

704102
stoichiometry: 1.0
species: 303042
type: SpeciesReference

720523
stoichiometry: 1.0
species: 302620
type: SpeciesReference

701114
stoichiometry: 0.02
species: 302529
type: SpeciesReference

304786
value: 0.0
type: LocalParameter

302734
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: O2_O2
type: Species

703291
stoichiometry: 1.0
species: 302517
type: SpeciesReference

304456
value: 0.0
type: LocalParameter

303298
kinetic law: 703677
product: 703665
reactant: 703653
notes: Abbreviation: R_EX_gln_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : gln-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Glutamine exchange
type: Reaction

712121
stoichiometry: 1.0
species: 302853
type: SpeciesReference

708637
stoichiometry: 1.0
species: 302720
type: SpeciesReference

706353
stoichiometry: 1.0
species: 302868
type: SpeciesReference

699694
stoichiometry: 1.0
species: 302628
type: SpeciesReference

698156
stoichiometry: 1.0
species: 302865
type: SpeciesReference

304899
value: 0.0
type: LocalParameter

707617
stoichiometry: 1.0
species: 302526
type: SpeciesReference

717913
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304709
value: 0.0
type: LocalParameter

302645
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Glycolate_C2H3O3
type: Species

305641
value: 0.0
type: LocalParameter

302420
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate_C12H13NO9P
type: Species

718709
stoichiometry: 1.0
species: 302526
type: SpeciesReference

721901
stoichiometry: 2.0
species: 302659
type: SpeciesReference

703885
stoichiometry: 1.0
species: 303032
type: SpeciesReference

304455
value: 0.0
type: LocalParameter

305310
value: 0.0
type: LocalParameter

302735
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Superoxide anion_O2
type: Species

719605
stoichiometry: 1.0
species: 302914
type: SpeciesReference

303297
kinetic law: 703641
product: 703629
reactant: 703617
notes: Abbreviation: R_EX_fum_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : fum <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Fumarate exchange
type: Reaction

714371
stoichiometry: 1.0
species: 302719
type: SpeciesReference

304787
value: 0.0
type: LocalParameter

717383
stoichiometry: 1.0
species: 302659
type: SpeciesReference

716032
stoichiometry: 1.0
species: 302413
type: SpeciesReference

708516
stoichiometry: 1.0
species: 302720
type: SpeciesReference

302646
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Glycolate_C2H3O3
type: Species

304708
value: 0.0
type: LocalParameter

302421
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate_C7H10O10P
type: Species

701452
stoichiometry: 1.0
species: 302493
type: SpeciesReference

303990
value: 0.0
type: LocalParameter

305644
value: 0.0
type: LocalParameter

697677
stoichiometry: 1.0
species: 302617
type: SpeciesReference

305313
value: 0.0
type: LocalParameter

700187
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304030
value: 999999.0
type: LocalParameter

713611
stoichiometry: 1.0
species: 302770
type: SpeciesReference

304458
value: -999999.0
type: LocalParameter

700787
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304788
value: -999999.0
type: LocalParameter

718335
stoichiometry: 1.0
species: 302500
type: SpeciesReference

695915
stoichiometry: 1.0
species: 302493
type: SpeciesReference

715675
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304707
value: 999999.0
type: LocalParameter

696107
stoichiometry: 1.0
species: 302511
type: SpeciesReference

707884
stoichiometry: 1.0
species: 302633
type: SpeciesReference

305643
value: 0.0
type: LocalParameter

303991
value: 0.0
type: LocalParameter

305312
value: 0.0
type: LocalParameter

700751
stoichiometry: 1.0
species: 302493
type: SpeciesReference

709195
stoichiometry: 1.0
species: 302724
type: SpeciesReference

303430
kinetic law: 707039
type: Reaction
notes: Abbreviation: R_GTPCI Synonyms: _0 EC Number: 3.5.4.16 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : gtp + h2o --> ahdt + for Confidence Level: 2 The reaction involves hydrolysis of two C-N bonds and isomerization of the pentose unit; the recyclization may be non-enzymic genes: LOCUS:BLBBGE_570#ABBREVIATION:folE#ECNUMBERS:3.5.4.16# proteins: NAME:GTP cyclohydrolase I#ABBREVIATION:FolE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_570)
product: 707015
reversible: false
fast: false
reactant: 707003
product: 707027
reactant: 706991
name: GTP cyclohydrolase I

700812
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304789
value: 999999.0
type: LocalParameter

304706
value: 0.0
type: LocalParameter

304819
value: 0.0
type: LocalParameter

716537
stoichiometry: 1.0
species: 302536
type: SpeciesReference

302422
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Demethylmenaquinone 8_C50H70O2
type: Species

302648
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: GMP_C10H12N5O8P
type: Species

717056
stoichiometry: 1.0
species: 302652
type: SpeciesReference

302536
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: CO2_CO2
type: Species

305048
value: 0.0
type: LocalParameter

702494
stoichiometry: 1.0
species: 302655
type: SpeciesReference

717164
stoichiometry: 1.0
species: 302425
type: SpeciesReference

303439
reversible: false
name: L-histidine transport via ABC system
product: 707377
product: 707365
fast: false
notes: Abbreviation: R_HISabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + his-L[e] --> adp[c] + h[c] + his-L[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 707316
reactant: 707304
type: Reaction
product: 707340
reactant: 707328
kinetic law: 707389
product: 707353

706244
stoichiometry: 1.0
species: 302659
type: SpeciesReference

710694
stoichiometry: 1.0
species: 302710
type: SpeciesReference

303905
value: 0.0
type: LocalParameter

304895
value: 0.0
type: LocalParameter

303089
reactant: 695335
type: Reaction
notes: Abbreviation: R_ACOTA Synonyms: _0 EC Number: 2.6.1.11 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : acorn + akg <==> acg5sa + glu-L Confidence Level: 2 genes: LOCUS:BLBBGE_315#ABBREVIATION:argD#ECNUMBERS:2.6.1.11,-!-,2.6.1.17# LOCUS:BLBBGE_623#ABBREVIATION:argD#ECNUMBERS:2.6.1.11,-!-,2.6.1.17# proteins: NAME:acetylornithine transaminase#ABBREVIATION:ArgD# NAME:acetylornithine transaminase#ABBREVIATION:ArgD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_315) or (BLBBGE_623)
fast: false
product: 695347
reactant: 695323
product: 695359
kinetic law: 695372
reversible: true
name: acetylornithine transaminase

303294
kinetic law: 703605
product: 703593
reactant: 703581
notes: Abbreviation: R_EX_fru_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : fru <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: D-Fructose exchange
type: Reaction

714481
stoichiometry: 1.0
species: 302456
type: SpeciesReference

706425
stoichiometry: 1.0
species: 302660
type: SpeciesReference

712230
stoichiometry: 1.0
species: 302980
type: SpeciesReference

304185
value: 0.0
type: LocalParameter

305751
value: 999999.0
type: LocalParameter

303992
value: 999999.0
type: LocalParameter

302738
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Oxaloacetate_C4H2O5
type: Species

712994
stoichiometry: 1.0
species: 302551
type: SpeciesReference

304039
value: 0.0
type: LocalParameter

302537
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: CO2_CO2
type: Species

304817
value: 0.0
type: LocalParameter

305047
value: 999999.0
type: LocalParameter

706123
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303904
value: 999999.0
type: LocalParameter

304896
value: 0.0
type: LocalParameter

305201
value: 0.0
type: LocalParameter

304184
value: 999999.0
type: LocalParameter

303293
kinetic law: 703569
product: 703557
reactant: 703545
notes: Abbreviation: R_EX_for_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : for <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Formate exchange
type: Reaction

305290
value: 0.0
type: LocalParameter

303993
value: 0.0
type: LocalParameter

305750
value: 0.0
type: LocalParameter

700391
stoichiometry: 1.0
species: 302542
type: SpeciesReference

302739
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: all-trans-Octaprenyl diphosphate_C40H65O7P2
type: Species

701224
stoichiometry: 1.0
species: 302659
type: SpeciesReference

720475
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302538
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Coenzyme A_C21H32N7O16P3S
type: Species

303907
value: 0.0
type: LocalParameter

714215
stoichiometry: 1.0
species: 302538
type: SpeciesReference

304897
value: 999999.0
type: LocalParameter

717273
stoichiometry: 1.0
species: 302733
type: SpeciesReference

698377
stoichiometry: 0.087
species: 302542
type: SpeciesReference

304816
value: 0.0
type: LocalParameter

718226
stoichiometry: 1.0
species: 302416
type: SpeciesReference

716140
stoichiometry: 1.0
species: 302870
type: SpeciesReference

303087
notes: Abbreviation: R_ACODA Synonyms: _0 EC Number: 3.5.1.16 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : acorn + h2o --> ac + orn Confidence Level: 2 genes: LOCUS:BLBBGE_320#ABBREVIATION:argE#ECNUMBERS:3.5.1.16# proteins: NAME:acetylornithine deacetylase#ABBREVIATION:ArgE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_320)
reversible: false
fast: false
reactant: 695239
type: Reaction
name: acetylornithine deacetylase
reactant: 695227
product: 695251
product: 695263
kinetic law: 695275

703775
stoichiometry: 1.0
species: 303029
type: SpeciesReference

696893
stoichiometry: 1.0
species: 302853
type: SpeciesReference

697568
stoichiometry: 1.0
species: 302536
type: SpeciesReference

303994
value: 0.0
type: LocalParameter

305291
value: -999999.0
type: LocalParameter

720318
stoichiometry: 1.0
species: 302566
type: SpeciesReference

305753
value: 0.0
type: LocalParameter

697822
stoichiometry: 1.0
species: 302724
type: SpeciesReference

305049
value: 0.0
type: LocalParameter

717997
stoichiometry: 1.0
species: 302948
type: SpeciesReference

302539
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Cytosine_C4H5N3O
type: Species

304898
value: 0.0
type: LocalParameter

714949
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303906
value: 0.0
type: LocalParameter

695263
stoichiometry: 1.0
species: 302744
type: SpeciesReference

304815
value: 999999.0
type: LocalParameter

695323
stoichiometry: 1.0
species: 302485
type: SpeciesReference

700295
stoichiometry: 1.0
species: 302493
type: SpeciesReference

305203
value: -999999.0
type: LocalParameter

303088
kinetic law: 695311
product: 695299
reactant: 695287
notes: Abbreviation: R_ACONT Synonyms: _0 EC Number: 4.2.1.3 SUBSYSTEM: Citric Acid Cycle Equation: [c] : cit <==> icit Confidence Level: 2 SMP genes: LOCUS:BLBBGE_017#ABBREVIATION:acnA#ECNUMBERS:4.2.1.3# proteins: NAME:aconitase A#ABBREVIATION:AcnA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_017)
fast: false
reversible: true
name: aconitase
type: Reaction

698305
stoichiometry: 0.281
species: 302516
type: SpeciesReference

303321
kinetic law: 704078
product: 704066
reactant: 704054
notes: Abbreviation: R_EX_leu_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : leu-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Leucine exchange
type: Reaction

696216
stoichiometry: 1.0
species: 302683
type: SpeciesReference

305292
value: 999999.0
type: LocalParameter

305752
value: 0.0
type: LocalParameter

304186
value: 0.0
type: LocalParameter

304814
value: 0.0
type: LocalParameter

695615
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304239
value: 0.0
type: LocalParameter

706859
stoichiometry: 1.0
species: 302511
type: SpeciesReference

702277
stoichiometry: 1.0
species: 302440
type: SpeciesReference

303435
kinetic law: 707232
product: 707220
reactant: 707208
notes: Abbreviation: R_H2Ot Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h2o[c] <==> h2o[e] Confidence Level: 1 renamed from H20t5 to H2Ot NCD genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: H2O transport via diffusion
type: Reaction

305044
value: 0.0
type: LocalParameter

716345
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305755
value: 999999.0
type: LocalParameter

303996
value: 0.0
type: LocalParameter

714637
stoichiometry: 1.0
species: 302720
type: SpeciesReference

720609
stoichiometry: 1.0
species: 302950
type: SpeciesReference

303290
kinetic law: 703533
product: 703521
reactant: 703509
notes: Abbreviation: R_EX_fe2_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : fe2 <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Fe2+ exchange
type: Reaction

702578
stoichiometry: 1.0
species: 302493
type: SpeciesReference

698945
stoichiometry: 10.0
species: 302724
type: SpeciesReference

305293
value: 0.0
type: LocalParameter

304036
value: 0.0
type: LocalParameter

708371
stoichiometry: 1.0
species: 302679
type: SpeciesReference

303322
kinetic law: 704114
product: 704102
reactant: 704090
notes: Abbreviation: R_EX_lys_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : lys-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Lysine exchange
type: Reaction

304891
value: 0.0
type: LocalParameter

305530
value: 0.0
type: LocalParameter

304813
value: 0.0
type: LocalParameter

303900
value: 0.0
type: LocalParameter

305649
value: 999999.0
type: LocalParameter

718649
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305043
value: 999999.0
type: LocalParameter

721245
stoichiometry: 1.0
species: 302632
type: SpeciesReference

304188
value: 0.0
type: LocalParameter

696047
stoichiometry: 1.0
species: 302493
type: SpeciesReference

305754
value: 0.0
type: LocalParameter

705567
stoichiometry: 1.0
species: 302483
type: SpeciesReference

304035
value: 0.0
type: LocalParameter

696918
stoichiometry: 1.0
species: 302504
type: SpeciesReference

708092
stoichiometry: 1.0
species: 302595
type: SpeciesReference

305294
value: 0.0
type: LocalParameter

305531
value: 0.0
type: LocalParameter

302888
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Pyridoxamine 5'-phosphate_C8H12N2O5P
type: Species

721004
stoichiometry: 1.0
species: 302958
type: SpeciesReference

304812
value: 0.0
type: LocalParameter

715454
stoichiometry: 1.0
species: 302459
type: SpeciesReference

716285
stoichiometry: 1.0
species: 302874
type: SpeciesReference

303998
value: 999999.0
type: LocalParameter

305757
value: 0.0
type: LocalParameter

711349
stoichiometry: 1.0
species: 302493
type: SpeciesReference

305046
value: 0.0
type: LocalParameter

304038
value: 999999.0
type: LocalParameter

303083
name: acetolactate synthase
product: 695142
notes: Abbreviation: R_ACLS Synonyms: _0 EC Number: 4.1.3.18 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : h + (2) pyr --> alac-S + co2 Confidence Level: 2 A flavoprotein. Requires thiamine diphosphate; also catalyses the formation of 2-aceto-2-hydroxybutanoate (see ACHBS) Also EC 2.2.1.6 - NCD genes: LOCUS:BLBBGE_556#ABBREVIATION:ilvI#ECNUMBERS:2.2.1.6# LOCUS:BLBBGE_555#ABBREVIATION:ilvH#ECNUMBERS:2.2.1.6# proteins: NAME:acetolactate synthase III#ABBREVIATION:IlvHI# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_555 and BLBBGE_556)
product: 695130
type: Reaction
reversible: false
fast: false
reactant: 695117
kinetic law: 695154
reactant: 695104

699754
stoichiometry: 1.0
species: 302633
type: SpeciesReference

305200
value: 0.0
type: LocalParameter

302889
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Pyridoxal 5'-phosphate_C8H8NO6P
type: Species

304893
value: 999999.0
type: LocalParameter

719823
stoichiometry: 1.0
species: 302940
type: SpeciesReference

303325
kinetic law: 704151
product: 704138
reactant: 704126
notes: Abbreviation: R_EX_mal_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : mal-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Malate exchange
type: Reaction

304811
value: 999999.0
type: LocalParameter

303438
fast: false
name: HCO3 equilibration reaction
type: Reaction
kinetic law: 707292
reactant: 707244
product: 707280
reversible: true
product: 707268
reactant: 707256
notes: Abbreviation: R_HCO3E Synonyms: _7 EC Number: 4.2.1.1 SUBSYSTEM: Unassigned Equation: [c] : co2 + h2o <==> h + hco3 Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:

304238
value: 999999.0
type: LocalParameter

707581
stoichiometry: 4.0
species: 302725
type: SpeciesReference

305756
value: 0.0
type: LocalParameter

719424
stoichiometry: 1.0
species: 302658
type: SpeciesReference

707725
stoichiometry: 1.0
species: 302723
type: SpeciesReference

303999
value: 0.0
type: LocalParameter

305045
value: 0.0
type: LocalParameter

303902
value: 0.0
type: LocalParameter

304037
value: 0.0
type: LocalParameter

699608
stoichiometry: 1.0
species: 302740
type: SpeciesReference

303084
type: Reaction
kinetic law: 695215
product: 695191
product: 695203
reversible: false
name: Acetyl-CoA ACP transacylase
fast: false
reactant: 695179
notes: Abbreviation: R_ACOATA Synonyms: _0 EC Number: 2.3.1.38 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : ACP + accoa --> acACP + coa Confidence Level: 2 tvrxn is now charge balanced; removed h - NCD genes: LOCUS:BLBBGE_111#ABBREVIATION:fabH#ECNUMBERS:2.3.1.41# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase#ABBREVIATION:FabH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_111)
reactant: 695167

716609
stoichiometry: 1.0
species: 302884
type: SpeciesReference

305296
value: -999999.0
type: LocalParameter

304894
value: 0.0
type: LocalParameter

302884
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: O-Phospho-L-serine_C3H6NO6P
type: Species

703183
stoichiometry: 1.0
species: 302477
type: SpeciesReference

713140
stoichiometry: 1.0
species: 302585
type: SpeciesReference

695543
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305523
value: 0.0
type: LocalParameter

305298
value: 999999.0
type: LocalParameter

303202
notes: Abbreviation: R_CYTDK2 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : cytd + gtp --> cmp + gdp + h Confidence Level: 2 genes: LOCUS:BLBBGE_535#ABBREVIATION:udk#ECNUMBERS:2.7.1.48# proteins: NAME:uridine/cytidine kinase#ABBREVIATION:Udk# citations: none GENE ASSOCIATION: (BLBBGE_535)
name: cytidine kinase (GTP)
product: 700691
reactant: 700655
type: Reaction
fast: false
product: 700679
product: 700703
reactant: 700667
kinetic law: 700715
reversible: false

696432
stoichiometry: 1.0
species: 302495
type: SpeciesReference

304393
value: 0.0
type: LocalParameter

303880
value: 999999.0
type: LocalParameter

711566
stoichiometry: 1.0
species: 302526
type: SpeciesReference

303082
type: Reaction
reactant: 695044
product: 695080
notes: Abbreviation: R_ACHBS Synonyms: _0 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 2obut + h + pyr --> 2ahbut + co2 Confidence Level: 2 JLR- I think the EC is 4.1.3.18 genes: LOCUS:BLBBGE_556#ABBREVIATION:ilvI#ECNUMBERS:2.2.1.6# LOCUS:BLBBGE_555#ABBREVIATION:ilvH#ECNUMBERS:2.2.1.6# proteins: NAME:acetolactate synthase III#ABBREVIATION:IlvHI# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_555 and BLBBGE_556)
kinetic law: 695092
reversible: false
product: 695068
name: _2-aceto-2-hydroxybutanoate synthase
reactant: 695056
fast: false
reactant: 695032

303658
reactant: 714769
fast: false
product: 714781
product: 714793
type: Reaction
reversible: true
name: L-phenylalanine reversible transport via proton symport
kinetic law: 714805
notes: Abbreviation: R_PHEt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h[e] + phe-L[e] <==> h[c] + phe-L[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 714757

720751
stoichiometry: 1.0
species: 302660
type: SpeciesReference

304248
value: 0.0
type: LocalParameter

304247
value: 0.0
type: LocalParameter

303000
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Xylulose 5-phosphate_C5H9O8P
type: Species

303774
product: 720402
notes: Abbreviation: R_TRDR Synonyms: _0 EC Number: 1.8.1.9 SUBSYSTEM: Oxidative Phosphorylation Equation: [c] : h + nadph + trdox --> nadp + trdrd Confidence Level: 2 genes: LOCUS:BLBBGE_045#ABBREVIATION:trxB#ECNUMBERS:1.8.1.9# proteins: NAME:Thioredoxin reductase#ABBREVIATION:TrxB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_045)
type: Reaction
reactant: 720366
name: thioredoxin reductase (NADPH)
product: 720390
fast: false
reversible: false
reactant: 720378
reactant: 720354
kinetic law: 720415

708492
stoichiometry: 1.0
species: 302719
type: SpeciesReference

719170
stoichiometry: 1.0
species: 302600
type: SpeciesReference

304392
value: 999999.0
type: LocalParameter

711530
stoichiometry: 1.0
species: 302493
type: SpeciesReference

709460
stoichiometry: 1.0
species: 302692
type: SpeciesReference

303081
reactant: 694972
name: N-acetylglutamate synthase
reversible: false
product: 695008
notes: Abbreviation: R_ACGS Synonyms: _0 EC Number: 2.3.1.1 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : accoa + glu-L --> acglu + coa + h Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
type: Reaction
reactant: 694960
kinetic law: 695020
fast: false
product: 694996
product: 694984

695482
stoichiometry: 1.0
species: 302475
type: SpeciesReference

304810
value: 0.0
type: LocalParameter

305040
value: 0.0
type: LocalParameter

719388
stoichiometry: 1.0
species: 302918
type: SpeciesReference

709303
stoichiometry: 1.0
species: 302493
type: SpeciesReference

302883
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: phosphatidylserine (Blattabacterium Blattella germanica)_C1986H3698N50O500P50
type: Species

704693
stoichiometry: 1.0
species: 303068
type: SpeciesReference

305521
value: 0.0
type: LocalParameter

304300
value: 0.0
type: LocalParameter

304246
value: 999999.0
type: LocalParameter

302959
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
type: Species

715752
stoichiometry: 1.0
species: 302868
type: SpeciesReference

302531
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: chorismate_C10H8O6
type: Species

303080
type: Reaction
product: 694936
fast: false
reversible: false
product: 694924
reactant: 694912
notes: Abbreviation: R_ACGK Synonyms: _0 EC Number: 2.7.2.8 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : acglu + atp --> acg5p + adp Confidence Level: 2 genes: LOCUS:BLBBGE_319#ABBREVIATION:argB#ECNUMBERS:2.7.2.8# proteins: NAME:acetylglutamate kinase#ABBREVIATION:ArgB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_319)
kinetic law: 694948
name: acetylglutamate kinase
reactant: 694900

699223
stoichiometry: 6.0
species: 302655
type: SpeciesReference

304391
value: 0.0
type: LocalParameter

303882
value: 0.0
type: LocalParameter

303777
reversible: false
product: 720535
name: tryptophan synthase (indoleglycerol phosphate)
notes: Abbreviation: R_TRPS1 Synonyms: _0 EC Number: 4.2.1.20 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : 3ig3p + ser-L --> g3p + h2o + trp-L Confidence Level: 2 genes: LOCUS:BLBBGE_426#ABBREVIATION:trpA#ECNUMBERS:4.2.1.20# LOCUS:BLBBGE_425#ABBREVIATION:trpB#ECNUMBERS:4.2.1.20# proteins: NAME:Tryptophan synthase#ABBREVIATION:TrpA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_426 and BLBBGE_425)
product: 720523
product: 720547
reactant: 720511
fast: false
kinetic law: 720559
type: Reaction
reactant: 720499

718298
stoichiometry: 1.0
species: 302914
type: SpeciesReference

707099
stoichiometry: 2.0
species: 302659
type: SpeciesReference

305041
value: 0.0
type: LocalParameter

713587
stoichiometry: 1.0
species: 302743
type: SpeciesReference

305520
value: 999999.0
type: LocalParameter

305299
value: 0.0
type: LocalParameter

713467
stoichiometry: 1.0
species: 302533
type: SpeciesReference

703557
stoichiometry: 1.0
species: 303019
type: SpeciesReference

701550
stoichiometry: 1.0
species: 302445
type: SpeciesReference

304245
value: 0.0
type: LocalParameter

302885
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Putrescine_C4H14N2
type: Species

302958
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
type: Species

303881
value: 0.0
type: LocalParameter

710936
stoichiometry: 1.0
species: 302719
type: SpeciesReference

304390
value: 0.0
type: LocalParameter

697604
stoichiometry: 1.0
species: 302655
type: SpeciesReference

695831
stoichiometry: 1.0
species: 302511
type: SpeciesReference

304929
value: 999999.0
type: LocalParameter

303776
name: triokinase
reversible: false
product: 720451
reactant: 720427
product: 720475
notes: Abbreviation: R_TRIOK Synonyms: _0 EC Number: 2.7.1.28 SUBSYSTEM: Fructose and Mannose Metabolism Equation: [c] : atp + glyald --> adp + g3p + h Confidence Level: 2 genes: LOCUS:BLBBGE_459#ABBREVIATION:glpK#ECNUMBERS:2.7.1.28,-!-,2.7.1.30# proteins: NAME:glycerol kinase#ABBREVIATION:GlpK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_459)
kinetic law: 720487
reactant: 720439
type: Reaction
product: 720463
fast: false

709983
stoichiometry: 1.0
species: 302702
type: SpeciesReference

702929
stoichiometry: 1.0
species: 302588
type: SpeciesReference

708953
stoichiometry: 1.0
species: 302412
type: SpeciesReference

704615
stoichiometry: 1.0
species: 303066
type: SpeciesReference

717491
stoichiometry: 1.0
species: 302894
type: SpeciesReference

709267
stoichiometry: 1.0
species: 302614
type: SpeciesReference

700307
stoichiometry: 1.0
species: 302542
type: SpeciesReference

305042
value: 0.0
type: LocalParameter

303659
product: 714841
reactant: 714817
reactant: 714829
type: Reaction
reversible: true
name: phenylalanine transaminase
product: 714853
fast: false
kinetic law: 714865
notes: Abbreviation: R_PHETA1 Synonyms: _5 EC Number: 2.6.1.58 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : akg + phe-L <==> glu-L + phpyr Confidence Level: 2 genes: LOCUS:BLBBGE_355#ABBREVIATION:aspC#ECNUMBERS:2.6.1.1# LOCUS:BLBBGE_455#ABBREVIATION:ilvE#ECNUMBERS:2.6.1.42,-!-,2.6.1.2# LOCUS:BLBBGE_342#ABBREVIATION:tyrB#ECNUMBERS:2.6.1.57# proteins: NAME:Tyrosine aminotransferase#ABBREVIATION:TyrB# NAME:Branched-chain-amino-acid aminotransferase#ABBREVIATION:IlvE# NAME:aspartate aminotransferase#ABBREVIATION:AspC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_455) or (BLBBGE_342) or (BLBBGE_355)

303203
reversible: true
kinetic law: 700775
product: 700763
type: Reaction
notes: Abbreviation: R_CYTK1 Synonyms: _0 EC Number: 2.7.4.14 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + cmp <==> adp + cdp Confidence Level: 2 genes: LOCUS:BLBBGE_058#ABBREVIATION:cmk#ECNUMBERS:2.7.4.14# proteins: NAME:cytidine monophosphate kinase#ABBREVIATION:Cmk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_058)
product: 700751
fast: false
reactant: 700739
reactant: 700727
name: cytidylate kinase (CMP)

304103
value: 0.0
type: LocalParameter

699331
stoichiometry: 6.0
species: 302536
type: SpeciesReference

712352
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304244
value: 0.0
type: LocalParameter

304302
value: 999999.0
type: LocalParameter

716838
stoichiometry: 1.0
species: 302492
type: SpeciesReference

304397
value: 0.0
type: LocalParameter

703701
stoichiometry: 1.0
species: 303025
type: SpeciesReference

715527
stoichiometry: 1.0
species: 302864
type: SpeciesReference

304180
value: 999999.0
type: LocalParameter

698739
stoichiometry: 0.054
species: 302950
type: SpeciesReference

305527
value: 0.0
type: LocalParameter

303654
fast: false
notes: Abbreviation: R_PGK Synonyms: _0 EC Number: 2.7.2.3 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : 3pg + atp <==> 13dpg + adp Confidence Level: 2 SMP genes: LOCUS:BLBBGE_294#ABBREVIATION:pgk#ECNUMBERS:2.7.2.3# proteins: NAME:phosphoglycerate kinase#ABBREVIATION:Pgk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_294)
reactant: 714673
product: 714697
type: Reaction
reactant: 714661
name: phosphoglycerate kinase
product: 714685
kinetic law: 714709
reversible: true

302880
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Phospho-alpha-D-ribose 1-diphosphate_C5H8O14P3
type: Species

716983
stoichiometry: 1.0
species: 302652
type: SpeciesReference

714299
stoichiometry: 1.0
species: 302733
type: SpeciesReference

303779
kinetic law: 720674
product: 720661
product: 720648
reactant: 720635
notes: Abbreviation: R_TRPS3 Synonyms: _0 EC Number: 4.2.1.20 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : 3ig3p --> g3p + indole Confidence Level: 2 JLR genes: LOCUS:BLBBGE_426#ABBREVIATION:trpA#ECNUMBERS:4.2.1.20# LOCUS:BLBBGE_425#ABBREVIATION:trpB#ECNUMBERS:4.2.1.20# proteins: NAME:Tryptophan synthase#ABBREVIATION:TrpA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_426 and BLBBGE_425)
fast: false
reversible: false
name: tryptophan synthase (indoleglycerol phosphate)
type: Reaction

302533
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Citrulline_C6H13N3O3
type: Species

702506
stoichiometry: 1.0
species: 302574
type: SpeciesReference

711747
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304102
value: 0.0
type: LocalParameter

698885
stoichiometry: 1.0
species: 302853
type: SpeciesReference

711843
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304181
value: 0.0
type: LocalParameter

705335
stoichiometry: 1.0
species: 302614
type: SpeciesReference

707957
stoichiometry: 1.0
species: 302723
type: SpeciesReference

304243
value: 0.0
type: LocalParameter

304396
value: 999999.0
type: LocalParameter

304669
value: 999999.0
type: LocalParameter

305526
value: 0.0
type: LocalParameter

304303
value: 0.0
type: LocalParameter

302532
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Citrate_C6H5O7
type: Species

717515
stoichiometry: 1.0
species: 302893
type: SpeciesReference

715225
stoichiometry: 2.0
species: 302853
type: SpeciesReference

699983
stoichiometry: 1.0
species: 302479
type: SpeciesReference

303778
product: 720609
reversible: false
reactant: 720584
reactant: 720572
notes: Abbreviation: R_TRPS2 Synonyms: _0 EC Number: 4.2.1.20 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : indole + ser-L --> h2o + trp-L Confidence Level: 2 A pyridoxal-phosphate protein. Also catalyses the conversion of serine and indole into tryptophan and water, and of indoleglycerol phosphate into indole and glyceraldehyde phosphate (the latter reaction was listed formerly as EC 4.1.2.8). genes: LOCUS:BLBBGE_426#ABBREVIATION:trpA#ECNUMBERS:4.2.1.20# LOCUS:BLBBGE_425#ABBREVIATION:trpB#ECNUMBERS:4.2.1.20# proteins: NAME:Tryptophan synthase#ABBREVIATION:TrpA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_426 and BLBBGE_425)
name: tryptophan synthase (indole)
type: Reaction
product: 720597
fast: false
kinetic law: 720622

721464
stoichiometry: 1.0
species: 302723
type: SpeciesReference

701829
stoichiometry: 1.0
species: 302633
type: SpeciesReference

720005
stoichiometry: 1.0
species: 303000
type: SpeciesReference

703399
stoichiometry: 1.0
species: 302537
type: SpeciesReference

304101
value: 0.0
type: LocalParameter

305760
value: 0.0
type: LocalParameter

304511
value: 0.0
type: LocalParameter

304395
value: -999999.0
type: LocalParameter

304242
value: 999999.0
type: LocalParameter

304182
value: 0.0
type: LocalParameter

303543
product: 711068
product: 711056
product: 711032
name: NAD synthase (nh3)
product: 711044
reactant: 711020
kinetic law: 711081
reversible: false
reactant: 711008
type: Reaction
fast: false
reactant: 710996
notes: Abbreviation: R_NADS1 Synonyms: _0 EC Number: 6.3.1.5 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + dnad + nh4 --> amp + h + nad + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_571#ABBREVIATION:nadE#ECNUMBERS:6.3.5.1# proteins: NAME:Deamido-NAD ammonia ligase or NAD synthetase#ABBREVIATION:NadE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_571)

719497
stoichiometry: 1.0
species: 302620
type: SpeciesReference

304304
value: 0.0
type: LocalParameter

305190
value: 0.0
type: LocalParameter

305525
value: 999999.0
type: LocalParameter

697298
stoichiometry: 1.0
species: 302512
type: SpeciesReference

708164
stoichiometry: 1.0
species: 302682
type: SpeciesReference

718869
stoichiometry: 2.0
species: 302735
type: SpeciesReference

304100
value: 999999.0
type: LocalParameter

700067
stoichiometry: 1.0
species: 302539
type: SpeciesReference

305761
value: 0.0
type: LocalParameter

304394
value: 0.0
type: LocalParameter

713031
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304241
value: -999999.0
type: LocalParameter

304510
value: 999999.0
type: LocalParameter

710478
stoichiometry: 1.0
species: 302630
type: SpeciesReference

304183
value: 0.0
type: LocalParameter

303151
reactant: 697822
fast: false
product: 697834
notes: Abbreviation: R_ASAD Synonyms: _0 EC Number: 1.2.1.11 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : 4pasp + h + nadph --> aspsa + nadp + pi Confidence Level: 2 genes: LOCUS:BLBBGE_299#ABBREVIATION:asd#ECNUMBERS:1.2.1.11# proteins: NAME:Aspartate-semialdehyde dehydrogenase#ABBREVIATION:Asd# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_299)
name: aspartate-semialdehyde dehydrogenase
reactant: 697798
kinetic law: 697870
reversible: false
type: Reaction
reactant: 697810
product: 697858
product: 697846

303542
type: Reaction
product: 710960
notes: Abbreviation: R_NADK Synonyms: _0 EC Number: 2.7.1.23 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + nad --> adp + h + nadp Confidence Level: 2 genes: LOCUS:BLBBGE_086#ABBREVIATION:ppnK#ECNUMBERS:2.7.1.23# proteins: NAME:NAD kinase#ABBREVIATION:ppnK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_086)
kinetic law: 710984
product: 710948
reversible: false
fast: false
product: 710972
reactant: 710923
reactant: 710936
name: NAD kinase

715249
stoichiometry: 1.0
species: 302863
type: SpeciesReference

304305
value: -999999.0
type: LocalParameter

303655
kinetic law: 714745
product: 714733
reactant: 714721
notes: Abbreviation: R_PGM Synonyms: _0 EC Number: 5.4.2.1 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : 2pg <==> 3pg Confidence Level: 2 SMP genes: LOCUS:BLBBGE_231#ABBREVIATION:gpmA#ECNUMBERS:5.4.2.1# proteins: NAME:phosphoglycerate mutase I#ABBREVIATION:GpmA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_231)
fast: false
reversible: true
name: phosphoglycerate mutase
type: Reaction

305524
value: 0.0
type: LocalParameter

721089
stoichiometry: 1.0
species: 302483
type: SpeciesReference

702048
stoichiometry: 1.0
species: 302709
type: SpeciesReference

302534
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: CMP_C9H12N3O8P
type: Species

708152
stoichiometry: 1.0
species: 302655
type: SpeciesReference

707377
stoichiometry: 1.0
species: 302853
type: SpeciesReference

302642
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Glycerol_C3H8O3
type: Species

708224
stoichiometry: 1.0
species: 302536
type: SpeciesReference

701939
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303888
value: 999999.0
type: LocalParameter

304513
value: -999999.0
type: LocalParameter

711951
stoichiometry: 1.0
species: 302580
type: SpeciesReference

304922
value: 0.0
type: LocalParameter

304306
value: 999999.0
type: LocalParameter

305192
value: 0.0
type: LocalParameter

305418
value: 0.0
type: LocalParameter

305302
value: 0.0
type: LocalParameter

304463
value: 0.0
type: LocalParameter

303152
product: 697906
notes: Abbreviation: R_ASNt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: asn-L[e] + h[e] <==> asn-L[c] + h[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 697894
fast: false
name: L-asparagine reversible transport via proton symport
type: Reaction
reversible: true
product: 697918
kinetic law: 697930
reactant: 697882

303650
kinetic law: 714577
product: 714565
reactant: 714553
notes: Abbreviation: R_PGAMT Synonyms: _0 EC Number: 5.4.2.10 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : gam1p <==> gam6p Confidence Level: 2 involved in the pathway for bacterial cell-wall peptidoglycan and lipopolysaccharide biosyntheses, being an essential step in the pathway for UDP-N-acetylglucosamine biosynthesis. genes: LOCUS:BLBBGE_157#ABBREVIATION:manB#ECNUMBERS:5.4.2.10# proteins: NAME:phosphoglucomutase/phosphomannomutase family protein#ABBREVIATION:manB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_157)
fast: false
reversible: true
name: phosphoglucosamine mutase
type: Reaction

705069
stoichiometry: 1.0
species: 302604
type: SpeciesReference

703231
stoichiometry: 1.0
species: 303004
type: SpeciesReference

714841
stoichiometry: 1.0
species: 302633
type: SpeciesReference

304240
value: 0.0
type: LocalParameter

699199
stoichiometry: 5.0
species: 302487
type: SpeciesReference

709533
stoichiometry: 1.0
species: 302692
type: SpeciesReference

303887
value: -999999.0
type: LocalParameter

721573
stoichiometry: 1.0
species: 302613
type: SpeciesReference

305417
value: 0.0
type: LocalParameter

304923
value: 999999.0
type: LocalParameter

304512
value: 0.0
type: LocalParameter

304307
value: 0.0
type: LocalParameter

694742
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305303
value: 999999.0
type: LocalParameter

711262
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304665
value: 0.0
type: LocalParameter

304464
value: 999999.0
type: LocalParameter

305650
value: 0.0
type: LocalParameter

302641
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Glycerol 3-phosphate_C3H7O6P
type: Species

718978
stoichiometry: 1.0
species: 302904
type: SpeciesReference

302644
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Glycerol_C3H8O3
type: Species

720066
stoichiometry: 1.0
species: 302945
type: SpeciesReference

304920
value: 0.0
type: LocalParameter

305529
value: 999999.0
type: LocalParameter

305304
value: 0.0
type: LocalParameter

303547
notes: Abbreviation: R_NAt3_1 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h[e] + na1[c] <==> h[c] + na1[e] Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 711201
product: 711225
product: 711237
fast: false
type: Reaction
reversible: true
reactant: 711213
kinetic law: 711250
name: sodium proton antiporter (H:NA is 1:1)

304308
value: 0.0
type: LocalParameter

305194
value: 999999.0
type: LocalParameter

305416
value: 999999.0
type: LocalParameter

304515
value: 0.0
type: LocalParameter

304465
value: 0.0
type: LocalParameter

304399
value: 0.0
type: LocalParameter

706581
stoichiometry: 1.0
species: 302725
type: SpeciesReference

305651
value: 0.0
type: LocalParameter

707268
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303889
value: 0.0
type: LocalParameter

303546
notes: Abbreviation: R_NAMNPP Synonyms: _1 EC Number: 2.4.2.11 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + h2o + nac + prpp --> adp + nicrnt + pi + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_208#ABBREVIATION:pncB#ECNUMBERS:2.4.2.11# proteins: NAME:Nicotinate phosphoribosyltransferase#ABBREVIATION:PncB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_208)
fast: false
product: 711141
reactant: 711117
reactant: 711105
name: nicotinic acid mononucleotide pyrophosphorylase
reversible: false
product: 711177
reactant: 711093
product: 711165
type: Reaction
kinetic law: 711189
reactant: 711129
product: 711153

304921
value: 0.0
type: LocalParameter

305305
value: 0.0
type: LocalParameter

305528
value: -999999.0
type: LocalParameter

305415
value: 0.0
type: LocalParameter

304309
value: 0.0
type: LocalParameter

304667
value: 0.0
type: LocalParameter

304514
value: 999999.0
type: LocalParameter

305195
value: 0.0
type: LocalParameter

714733
stoichiometry: 1.0
species: 302446
type: SpeciesReference

703075
stoichiometry: 1.0
species: 302719
type: SpeciesReference

303155
product: 697979
kinetic law: 697991
product: 697967
fast: false
reactant: 697955
type: Reaction
notes: Abbreviation: R_ASPK Synonyms: _0 EC Number: 2.7.2.4 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : asp-L + atp --> 4pasp + adp Confidence Level: 2 genes: LOCUS:BLBBGE_501#ABBREVIATION:thrA#ECNUMBERS:2.7.2.4,-!-,1.1.1.3# proteins: NAME:Homoserine dehydrogenase#ABBREVIATION:MetL# NAME:Aspartate kinase I#ABBREVIATION:ThrA# NAME:Aspartokinase III#ABBREVIATION:LysC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_501)
reversible: false
name: aspartate kinase
reactant: 697943

302950
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Tryptophan_C11H12N2O2
type: Species

304466
value: 0.0
type: LocalParameter

713732
stoichiometry: 1.0
species: 302454
type: SpeciesReference

303651
product: 714613
product: 714625
name: phosphoglycerate dehydrogenase
reversible: true
reactant: 714601
product: 714637
kinetic law: 714649
reactant: 714589
type: Reaction
fast: false
notes: Abbreviation: R_PGCD Synonyms: _0 EC Number: 1.1.1.95 SUBSYSTEM: Glycine and Serine Metabolism Equation: [c] : 3pg + nad <==> 3php + h + nadh Confidence Level: 2 genes: LOCUS:BLBBGE_283#ABBREVIATION:serA#ECNUMBERS:1.1.1.95# proteins: NAME:Phosphoglycerate dehydrogenase#ABBREVIATION:SerA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_283)

706871
stoichiometry: 1.0
species: 302633
type: SpeciesReference

304398
value: 0.0
type: LocalParameter

706099
stoichiometry: 1.0
species: 302526
type: SpeciesReference

719278
stoichiometry: 1.0
species: 302853
type: SpeciesReference

303206
product: 700825
kinetic law: 700837
product: 700812
notes: Abbreviation: R_CYTK2 Synonyms: _0 EC Number: 2.7.4.14 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dcmp <==> adp + dcdp Confidence Level: 2 genes: LOCUS:BLBBGE_058#ABBREVIATION:cmk#ECNUMBERS:2.7.4.14# proteins: NAME:cytidine monophosphate kinase#ABBREVIATION:Cmk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_058)
name: cytidylate kinase (dCMP)
reactant: 700787
fast: false
reversible: true
type: Reaction
reactant: 700800

305414
value: 0.0
type: LocalParameter

710586
stoichiometry: 1.0
species: 302730
type: SpeciesReference

304517
value: 0.0
type: LocalParameter

302428
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Octaprenyl-6-methoxy-1,4-benzoquinol_C47H72O3
type: Species

702723
stoichiometry: 1.0
species: 302584
type: SpeciesReference

696192
stoichiometry: 1.0
species: 302522
type: SpeciesReference

719062
stoichiometry: 1.0
species: 302925
type: SpeciesReference

303884
value: 999999.0
type: LocalParameter

303771
product: 720234
notes: Abbreviation: R_TMDPP Synonyms: _0 EC Number: 2.4.2.4 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : pi + thymd <==> 2dr1p + thym Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
type: Reaction
reactant: 720198
kinetic law: 720246
name: thymidine phosphorylase
product: 720222
reactant: 720210

712193
stoichiometry: 1.0
species: 302853
type: SpeciesReference

719762
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304791
value: 0.0
type: LocalParameter

302953
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Tryptophan_C11H12N2O2
type: Species

304662
value: -999999.0
type: LocalParameter

303156
product: 698039
notes: Abbreviation: R_ASPt2 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: asp-L[e] + h[e] --> asp-L[c] + h[c] Confidence Level: 2 genes: LOCUS:BLBBGE_358#ABBREVIATION:gltP# proteins: NAME:DAACS, glutamate or aspartate symport#ABBREVIATION:GltP# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_358)
name: L-aspartate transport in via proton symport
kinetic law: 698052
type: Reaction
reversible: false
reactant: 698015
fast: false
product: 698027
reactant: 698003

304701
value: 0.0
type: LocalParameter

304516
value: 0.0
type: LocalParameter

305307
value: 0.0
type: LocalParameter

302427
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Oxobutanoate_C4H5O3
type: Species

697140
stoichiometry: 1.0
species: 302423
type: SpeciesReference

304927
value: 0.0
type: LocalParameter

305197
value: 0.0
type: LocalParameter

699115
stoichiometry: 1.0
species: 302712
type: SpeciesReference

696324
stoichiometry: 1.0
species: 302985
type: SpeciesReference

303883
value: -999999.0
type: LocalParameter

710718
stoichiometry: 2.0
species: 302660
type: SpeciesReference

704504
stoichiometry: 1.0
species: 303061
type: SpeciesReference

304790
value: 0.0
type: LocalParameter

304460
value: 999999.0
type: LocalParameter

304661
value: 0.0
type: LocalParameter

303157
name: aspartate transaminase
reactant: 698078
reactant: 698065
kinetic law: 698117
product: 698091
fast: false
type: Reaction
notes: Abbreviation: R_ASPTA Synonyms: _29 EC Number: 2.6.1.1 SUBSYSTEM: Alanine and Aspartate Metabolism Equation: [c] : akg + asp-L <==> glu-L + oaa Confidence Level: 2 genes: LOCUS:BLBBGE_355#ABBREVIATION:aspC#ECNUMBERS:2.6.1.1# proteins: NAME:aspartate aminotransferase#ABBREVIATION:AspC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_355)
reversible: true
product: 698104

705118
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303208
product: 700958
fast: false
kinetic law: 700970
name: deoxyadenylate kinase
reactant: 700921
product: 700945
reversible: true
notes: Abbreviation: R_DADK Synonyms: _0 EC Number: 2.7.4.11 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + damp <==> adp + dadp Confidence Level: 2 AMP can also act as acceptor genes: LOCUS:BLBBGE_215#ABBREVIATION:adk#ECNUMBERS:2.7.4.3# proteins: NAME:Adenylate kinase#ABBREVIATION:Adk# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_215)
type: Reaction
reactant: 700933

713938
stoichiometry: 1.0
species: 302920
type: SpeciesReference

304519
value: 0.0
type: LocalParameter

698221
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304924
value: 0.0
type: LocalParameter

703812
stoichiometry: 1.0
species: 303030
type: SpeciesReference

305198
value: 0.0
type: LocalParameter

303886
value: 0.0
type: LocalParameter

695987
stoichiometry: 1.0
species: 302511
type: SpeciesReference

710104
stoichiometry: 1.0
species: 302470
type: SpeciesReference

718929
stoichiometry: 1.0
species: 302538
type: SpeciesReference

302640
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: D-Glyceraldehyde_C3H6O3
type: Species

710899
stoichiometry: 1.0
species: 302719
type: SpeciesReference

303773
kinetic law: 720342
product: 720330
reactant: 720318
notes: Abbreviation: R_TPI Synonyms: _0 EC Number: 5.3.1.1 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : dhap <==> g3p Confidence Level: 2 SMP genes: LOCUS:BLBBGE_104#ABBREVIATION:tpiA#ECNUMBERS:5.3.1.1# proteins: NAME:triosephosphate isomerase#ABBREVIATION:Tpi# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_104)
fast: false
reversible: true
name: triose-phosphate isomerase
type: Reaction

698667
stoichiometry: 5.2E-5
species: 302883
type: SpeciesReference

697894
stoichiometry: 1.0
species: 302660
type: SpeciesReference

304664
value: 0.0
type: LocalParameter

305412
value: 0.0
type: LocalParameter

703665
stoichiometry: 1.0
species: 303024
type: SpeciesReference

304793
value: 999999.0
type: LocalParameter

304461
value: 0.0
type: LocalParameter

302955
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Tyrosine_C9H11NO3
type: Species

701660
stoichiometry: 1.0
species: 302524
type: SpeciesReference

304518
value: 999999.0
type: LocalParameter

303207
type: Reaction
reactant: 700873
kinetic law: 700909
reactant: 700849
reversible: false
product: 700897
notes: Abbreviation: R_DADA Synonyms: _0 EC Number: 3.5.4.4 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dad-2 + h + h2o --> din + nh4 Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
name: Deoxyadenosine deaminase
product: 700885
reactant: 700861
fast: false

304925
value: 0.0
type: LocalParameter

305309
value: 999999.0
type: LocalParameter

716765
stoichiometry: 1.0
species: 302526
type: SpeciesReference

712425
stoichiometry: 1.0
species: 302853
type: SpeciesReference

709110
stoichiometry: 1.0
species: 302489
type: SpeciesReference

305199
value: 999999.0
type: LocalParameter

303885
value: 0.0
type: LocalParameter

717841
stoichiometry: 1.0
species: 302655
type: SpeciesReference

720198
stoichiometry: 1.0
species: 302853
type: SpeciesReference

714143
stoichiometry: 1.0
species: 302740
type: SpeciesReference

709874
stoichiometry: 1.0
species: 302536
type: SpeciesReference

708844
stoichiometry: 1.0
species: 302508
type: SpeciesReference

697713
stoichiometry: 1.0
species: 302526
type: SpeciesReference

303772
product: 720282
reversible: false
type: Reaction
product: 720294
reactant: 720258
fast: false
reactant: 720270
notes: Abbreviation: R_TMDS Synonyms: _4 EC Number: 2.1.1.45 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dump + mlthf --> dhf + dtmp Confidence Level: 2 genes: LOCUS:BLBBGE_498#ABBREVIATION:thyA#ECNUMBERS:2.1.1.45# proteins: NAME:thymidylate synthetase#ABBREVIATION:ThyA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_498)
name: thymidylate synthase
kinetic law: 720306

305411
value: 999999.0
type: LocalParameter

304663
value: 999999.0
type: LocalParameter

695433
stoichiometry: 1.0
species: 302754
type: SpeciesReference

710827
stoichiometry: 1.0
species: 302719
type: SpeciesReference

302954
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Tyrosine_C9H11NO3
type: Species

304462
value: 0.0
type: LocalParameter

715309
stoichiometry: 1.0
species: 302493
type: SpeciesReference

696784
stoichiometry: 1.0
species: 302660
type: SpeciesReference

713358
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304792
value: 0.0
type: LocalParameter

717479
stoichiometry: 1.0
species: 302660
type: SpeciesReference

302659
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: H+_H
type: Species

302433
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-(4-Hydroxyphenyl)pyruvate_C9H7O4
type: Species

718070
stoichiometry: 1.0
species: 302900
type: SpeciesReference

304776
value: 0.0
type: LocalParameter

303478
reversible: false
product: 708625
product: 708637
type: Reaction
reactant: 708601
notes: Abbreviation: R_IPMD Synonyms: _0 EC Number: 1.1.1.85 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 3c2hmp + nad --> 3c4mop + h + nadh Confidence Level: 2 genes: LOCUS:BLBBGE_070#ABBREVIATION:leuB#ECNUMBERS:1.1.1.85# proteins: NAME:Isopropylmalate dehydrogenase#ABBREVIATION:LeuB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_070)
product: 708613
fast: false
kinetic law: 708650
name: _3-isopropylmalate dehydrogenase
reactant: 708589

718347
stoichiometry: 2.0
species: 302659
type: SpeciesReference

305349
value: 0.0
type: LocalParameter

718408
stoichiometry: 1.0
species: 302905
type: SpeciesReference

303264
name: deoxyuridine phosphorylase
product: 702868
reactant: 702855
reactant: 702843
reversible: true
notes: Abbreviation: R_DURIPP Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : duri + pi <==> 2dr1p + ura Confidence Level: 2 JLR genes: LOCUS:BLBBGE_377#ABBREVIATION:deoD#ECNUMBERS:2.4.2.1# proteins: NAME:Purine-nucleoside phosphorylase#ABBREVIATION:DeoD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_377)
fast: false
kinetic law: 702892
product: 702880
type: Reaction

704054
stoichiometry: 1.0
species: 302693
type: SpeciesReference

712035
stoichiometry: 1.0
species: 302588
type: SpeciesReference

302748
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Orotate_C5H3N2O4
type: Species

713491
stoichiometry: 1.0
species: 302853
type: SpeciesReference

701464
stoichiometry: 1.0
species: 302561
type: SpeciesReference

304042
value: -999999.0
type: LocalParameter

700151
stoichiometry: 1.0
species: 302628
type: SpeciesReference

697967
stoichiometry: 1.0
species: 302455
type: SpeciesReference

720597
stoichiometry: 1.0
species: 302655
type: SpeciesReference

717044
stoichiometry: 1.0
species: 302425
type: SpeciesReference

304777
value: 0.0
type: LocalParameter

305348
value: 999999.0
type: LocalParameter

695142
stoichiometry: 1.0
species: 302536
type: SpeciesReference

720090
stoichiometry: 1.0
species: 302584
type: SpeciesReference

303466
product: 708212
notes: Abbreviation: R_IGPS Synonyms: _0 EC Number: 4.1.1.48 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : 2cpr5p + h --> 3ig3p + co2 + h2o Confidence Level: 2 genes: LOCUS:BLBBGE_424#ABBREVIATION:trpC#ECNUMBERS:5.3.1.24,-!-,4.1.1.48# proteins: NAME:indole-3-glycerol-phosphate synthase#ABBREVIATION:TrpC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_424)
product: 708224
kinetic law: 708249
reactant: 708200
reactant: 708188
reversible: false
type: Reaction
name: indole-3-glycerol-phosphate synthase
fast: false
product: 708236

706569
stoichiometry: 1.0
species: 302720
type: SpeciesReference

712499
stoichiometry: 1.0
species: 302853
type: SpeciesReference

302749
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: phosphatidate (Blattabacterium Blattella germanica)_C1836H3398O400P50
type: Species

707160
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303318
kinetic law: 704042
product: 704030
reactant: 704018
notes: Abbreviation: R_EX_k_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : k <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: K+ exchange
type: Reaction

700849
stoichiometry: 1.0
species: 302547
type: SpeciesReference

708601
stoichiometry: 1.0
species: 302719
type: SpeciesReference

303463
kinetic law: 708176
product: 708164
product: 708152
reactant: 708140
notes: Abbreviation: R_IGPDH Synonyms: _0 EC Number: 4.2.1.19 SUBSYSTEM: Histidine Metabolism Equation: [c] : eig3p --> h2o + imacp Confidence Level: 2 genes: LOCUS:BLBBGE_436#ABBREVIATION:hisB#ECNUMBERS:3.1.3.15,-!-,4.2.1.19# proteins: NAME:Imidazoleglycerol phosphate dehydratase and Histidinol phosphatase#ABBREVIATION:HisB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_436)
fast: false
reversible: false
name: imidazoleglycerol-phosphate dehydratase
type: Reaction

304774
value: -999999.0
type: LocalParameter

698425
stoichiometry: 0.0365
species: 302585
type: SpeciesReference

720726
stoichiometry: 1.0
species: 302950
type: SpeciesReference

305347
value: 0.0
type: LocalParameter

699814
stoichiometry: 1.0
species: 302864
type: SpeciesReference

304040
value: 0.0
type: LocalParameter

720511
stoichiometry: 1.0
species: 302905
type: SpeciesReference

701102
stoichiometry: 0.02
species: 302749
type: SpeciesReference

302431
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Glycerate 2-phosphate_C3H4O7P
type: Species

706943
stoichiometry: 1.0
species: 302687
type: SpeciesReference

704321
stoichiometry: 1.0
species: 303052
type: SpeciesReference

717949
stoichiometry: 1.0
species: 302949
type: SpeciesReference

712873
stoichiometry: 1.0
species: 302556
type: SpeciesReference

302859
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: (R)-Pantothenate_C9H16NO5
type: Species

711469
stoichiometry: 1.0
species: 302493
type: SpeciesReference

302658
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Hydrogen sulfide_H2S
type: Species

716020
stoichiometry: 1.0
species: 302526
type: SpeciesReference

713987
stoichiometry: 1.0
species: 302965
type: SpeciesReference

304775
value: 999999.0
type: LocalParameter

698091
stoichiometry: 1.0
species: 302633
type: SpeciesReference

303261
reversible: false
product: 702795
product: 702807
kinetic law: 702831
type: Reaction
fast: false
notes: Abbreviation: R_DURIK1 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + duri --> adp + dump + h Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
name: deoxyuridine kinase (ATP:Deoxyuridine)
reactant: 702783
product: 702819
reactant: 702771

305346
value: 0.0
type: LocalParameter

303475
kinetic law: 708577
product: 708565
reactant: 708553
notes: Abbreviation: R_IPDDIi Synonyms: _0 EC Number: 5.3.3.2 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : ipdp <==> dmpp Confidence Level: 2 JLR- added irreversible form of IPDDI genes: LOCUS:BLBBGE_190#ABBREVIATION:idi#ECNUMBERS:5.3.3.2# proteins: NAME:isopentenyl diphosphate isomerase#ABBREVIATION:Idi# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_190)
fast: false
reversible: true
name: isopentenyl-diphosphate D-isomerase
type: Reaction

716092
stoichiometry: 1.0
species: 302655
type: SpeciesReference

713116
stoichiometry: 1.0
species: 302865
type: SpeciesReference

302432
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate_C11H10O6
type: Species

303139
reactant: 697274
product: 697322
fast: false
name: anthranilate synthase
reversible: false
product: 697310
product: 697335
reactant: 697286
product: 697298
type: Reaction
kinetic law: 697347
notes: Abbreviation: R_ANS Synonyms: _0 EC Number: 4.1.3.27 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : chor + gln-L --> anth + glu-L + h + pyr Confidence Level: 2 genes: LOCUS:BLBBGE_422#ABBREVIATION:trpD#ECNUMBERS:4.1.3.27,-!-,2.4.2.18# LOCUS:BLBBGE_421#ABBREVIATION:trpE#ECNUMBERS:4.1.3.27# proteins: NAME:Anthranilate synthase I#ABBREVIATION:TrpE# NAME:anthranilate synthase II#ABBREVIATION:TrpD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_421) and (BLBBGE_422)

706003
stoichiometry: 1.0
species: 302622
type: SpeciesReference

305612
value: 999999.0
type: LocalParameter

302589
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Deoxyuridine_C9H12N2O5
type: Species

302437
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Carboxy-4-methyl-2-oxopentanoate_C7H8O5
type: Species

715285
stoichiometry: 1.0
species: 302526
type: SpeciesReference

698003
stoichiometry: 1.0
species: 302523
type: SpeciesReference

695068
stoichiometry: 1.0
species: 302418
type: SpeciesReference

304159
value: 0.0
type: LocalParameter

304046
value: 0.0
type: LocalParameter

705787
stoichiometry: 1.0
species: 302659
type: SpeciesReference

702771
stoichiometry: 1.0
species: 302526
type: SpeciesReference

721973
stoichiometry: 1.0
species: 302988
type: SpeciesReference

701187
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305490
value: 0.0
type: LocalParameter

714589
stoichiometry: 1.0
species: 302446
type: SpeciesReference

719968
stoichiometry: 1.0
species: 302903
type: SpeciesReference

302744
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Ornithine_C5H13N2O2
type: Species

305345
value: 0.0
type: LocalParameter

303268
fast: false
reversible: false
notes: Abbreviation: R_DXPS Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : g3p + h + pyr --> co2 + dxyl5p Confidence Level: 1 EC 4.1.3.37 transferred to:EC 2.2.1.7NJ genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 703002
product: 703014
kinetic law: 703038
reactant: 702978
product: 703026
type: Reaction
reactant: 702990
name: _1-deoxy-D-xylulose 5-phosphate synthase

304772
value: 0.0
type: LocalParameter

699899
stoichiometry: 1.0
species: 302655
type: SpeciesReference

700235
stoichiometry: 1.0
species: 302853
type: SpeciesReference

303691
kinetic law: 715851
product: 715839
reactant: 715827
notes: Abbreviation: R_PRAIi Synonyms: _0 EC Number: 5.3.1.24 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : pran --> 2cpr5p Confidence Level: 2 JLR- added irreversible form of PRAI genes: LOCUS:BLBBGE_425#ABBREVIATION:trpFB#ECNUMBERS:5.3.1.24,-!-,4.1.1.48# proteins: NAME:Phosphoribosyl anthranilate isomerase#ABBREVIATION:TrpFB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_425)
fast: false
reversible: false
name: phosphoribosylanthranilate isomerase (irreversible)
type: Reaction

303317
kinetic law: 704006
product: 703994
reactant: 703982
notes: Abbreviation: R_EX_ile_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : ile-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Isoleucine exchange
type: Reaction

704913
stoichiometry: 1.0
species: 302566
type: SpeciesReference

302588
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dUMP_C9H11N2O8P
type: Species

302438
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Dehydroquinate_C7H9O6
type: Species

721634
stoichiometry: 1.0
species: 302507
type: SpeciesReference

304158
value: 999999.0
type: LocalParameter

304045
value: 0.0
type: LocalParameter

305611
value: -999999.0
type: LocalParameter

705931
stoichiometry: 1.0
species: 302645
type: SpeciesReference

305344
value: 999999.0
type: LocalParameter

706679
stoichiometry: 1.0
species: 302644
type: SpeciesReference

304773
value: 0.0
type: LocalParameter

710080
stoichiometry: 1.0
species: 302865
type: SpeciesReference

303692
kinetic law: 715936
reactant: 715875
name: phosphoribosylaminoimidazole synthase
type: Reaction
fast: false
reactant: 715863
product: 715887
product: 715899
notes: Abbreviation: R_PRAIS Synonyms: _0 EC Number: 6.3.3.1 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : atp + fpram --> adp + air + (2) h + pi Confidence Level: 2 genes: LOCUS:BLBBGE_482#ABBREVIATION:purM#ECNUMBERS:6.3.3.1# proteins: NAME:phosphoribosylaminoimidazole synthetase#ABBREVIATION:PurM# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_482)
product: 715911
reversible: false
product: 715923

720835
stoichiometry: 1.0
species: 302433
type: SpeciesReference

302745
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Orotidine 5'-phosphate_C10H10N2O11P
type: Species

707461
stoichiometry: 2.0
species: 302720
type: SpeciesReference

717321
stoichiometry: 1.0
species: 302889
type: SpeciesReference

303467
fast: false
name: L-isoleucine transport via ABC system
reactant: 708287
reactant: 708275
product: 708323
product: 708299
notes: Abbreviation: R_ILEabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + ile-L[e] --> adp[c] + h[c] + ile-L[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
kinetic law: 708347
product: 708335
reactant: 708262
type: Reaction
reversible: false
product: 708311

702132
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302508
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (S)-2-Acetolactate_C5H7O4
type: Species

303314
kinetic law: 703970
product: 703958
reactant: 703946
notes: Abbreviation: R_EX_his_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : his-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Histidine exchange
type: Reaction

302435
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Carboxy-2-hydroxy-4-methylpentanoate_C7H10O5
type: Species

305189
value: 0.0
type: LocalParameter

711409
stoichiometry: 1.0
species: 302493
type: SpeciesReference

305610
value: 0.0
type: LocalParameter

304044
value: 999999.0
type: LocalParameter

698800
stoichiometry: 45.56035
species: 302659
type: SpeciesReference

711819
stoichiometry: 1.0
species: 302725
type: SpeciesReference

304157
value: -999999.0
type: LocalParameter

305343
value: 0.0
type: LocalParameter

304770
value: 0.0
type: LocalParameter

711032
stoichiometry: 1.0
species: 302511
type: SpeciesReference

303479
kinetic law: 708698
product: 708686
product: 708674
reactant: 708662
notes: Abbreviation: R_IPPMIa Synonyms: _0 EC Number: 4.2.1.33 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 2ippm + h2o <==> 3c2hmp Confidence Level: 2 genes: LOCUS:BLBBGE_069#ABBREVIATION:leuD#ECNUMBERS:4.2.1.33,-!-,4.2.1.35# LOCUS:BLBBGE_068#ABBREVIATION:leuC#ECNUMBERS:4.2.1.33# proteins: NAME:Isopropylmalate isomerase small subunit#ABBREVIATION:LeuC# NAME:Isopropylmalate isomerase large subunit#ABBREVIATION:LeuD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_068 and BLBBGE_069)
fast: false
reversible: true
name: _3-isopropylmalate dehydratase
type: Reaction

695759
stoichiometry: 1.0
species: 302633
type: SpeciesReference

708018
stoichiometry: 1.0
species: 302531
type: SpeciesReference

302509
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: S-Adenosyl-L-methionine_C15H23N6O5S
type: Species

305188
value: 999999.0
type: LocalParameter

716201
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302436
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Carboxy-3-hydroxy-4-methylpentanoate_C7H10O5
type: Species

721865
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304156
value: 0.0
type: LocalParameter

715899
stoichiometry: 1.0
species: 302499
type: SpeciesReference

303265
notes: Abbreviation: R_DUTPDP Synonyms: _0 EC Number: 3.6.1.23 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dutp + h2o --> dump + h + ppi Confidence Level: 2 genes: LOCUS:BLBBGE_606#ABBREVIATION:dut#ECNUMBERS:3.6.1.23# LOCUS:BLBBGE_p003#ABBREVIATION:dut#ECNUMBERS:3.6.1.23# proteins: NAME:deoxyuridine 5'-triphosphate nucleotidohydrolase#ABBREVIATION:Dut# NAME:dUTP pyrophosphatase#ABBREVIATION:Dut# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_606) or (BLBBGE_p003)
reactant: 702904
kinetic law: 702966
type: Reaction
name: dUTP diphosphatase
product: 702941
product: 702929
reactant: 702916
product: 702953
reversible: false
fast: false

303136
type: Reaction
fast: false
product: 697238
reactant: 697214
kinetic law: 697262
reactant: 697226
product: 697250
notes: Abbreviation: R_ANPRT Synonyms: _0 EC Number: 2.4.2.18 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : anth + prpp --> ppi + pran Confidence Level: 2 genes: LOCUS:BLBBGE_423#ABBREVIATION:trpD#ECNUMBERS:4.1.3.27,-!-,2.4.2.18# proteins: NAME:anthranilate synthase II#ABBREVIATION:TrpD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_423)
reversible: false
name: anthranilate phosphoribosyltransferase

701611
stoichiometry: 1.0
species: 302724
type: SpeciesReference

305342
value: 0.0
type: LocalParameter

302743
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Oxo-3-hydroxy-4-phosphobutanoate_C4H4O8P
type: Species

704381
stoichiometry: 1.0
species: 302855
type: SpeciesReference

706715
stoichiometry: 1.0
species: 302642
type: SpeciesReference

304771
value: 999999.0
type: LocalParameter

302853
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Phosphate_HO4P
type: Species

305341
value: 0.0
type: LocalParameter

305564
value: 0.0
type: LocalParameter

304155
value: 0.0
type: LocalParameter

302585
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dTTP_C10H13N2O14P3
type: Species

305769
value: 999999.0
type: LocalParameter

303962
value: 999999.0
type: LocalParameter

305616
value: -999999.0
type: LocalParameter

719339
stoichiometry: 1.0
species: 302919
type: SpeciesReference

302506
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Alanine_C3H7NO2
type: Species

305829
value: 0.0
type: LocalParameter

716297
stoichiometry: 1.0
species: 302875
type: SpeciesReference

304848
value: 0.0
type: LocalParameter

305565
value: 0.0
type: LocalParameter

720944
stoichiometry: 1.0
species: 302978
type: SpeciesReference

305340
value: 999999.0
type: LocalParameter

705895
stoichiometry: 1.0
species: 302625
type: SpeciesReference

304049
value: 0.0
type: LocalParameter

721743
stoichiometry: 1.0
species: 302958
type: SpeciesReference

718106
stoichiometry: 1.0
species: 302651
type: SpeciesReference

304154
value: 999999.0
type: LocalParameter

302584
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dTMP_C10H13N2O8P
type: Species

303963
value: 0.0
type: LocalParameter

715393
stoichiometry: 1.0
species: 302753
type: SpeciesReference

701090
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303029
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: D-Glyceraldehyde_C3H6O3
type: Species

302507
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Alanyl-D-alanine_C6H12N2O3
type: Species

303313
kinetic law: 703934
product: 703922
reactant: 703910
notes: Abbreviation: R_EX_h_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : h <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: H+ exchange
type: Reaction

304847
value: 999999.0
type: LocalParameter

305566
value: 0.0
type: LocalParameter

706787
stoichiometry: 1.0
species: 302636
type: SpeciesReference

303310
kinetic law: 703898
product: 703885
reactant: 703872
notes: Abbreviation: R_EX_h2o_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : h2o <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: H2O exchange
type: Reaction

706823
stoichiometry: 1.0
species: 302628
type: SpeciesReference

304153
value: 0.0
type: LocalParameter

303960
value: 0.0
type: LocalParameter

304048
value: 999999.0
type: LocalParameter

702566
stoichiometry: 1.0
species: 302581
type: SpeciesReference

302504
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Alanine_C3H7NO2
type: Species

702241
stoichiometry: 1.0
species: 302865
type: SpeciesReference

305827
value: 999999.0
type: LocalParameter

302587
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dUDP_C9H11N2O11P2
type: Species

305614
value: 0.0
type: LocalParameter

305767
value: 0.0
type: LocalParameter

711518
stoichiometry: 1.0
species: 302561
type: SpeciesReference

712524
stoichiometry: 1.0
species: 302511
type: SpeciesReference

305567
value: 999999.0
type: LocalParameter

701951
stoichiometry: 1.0
species: 302865
type: SpeciesReference

704840
stoichiometry: 1.0
species: 303076
type: SpeciesReference

696035
stoichiometry: 1.0
species: 302526
type: SpeciesReference

705703
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304152
value: 0.0
type: LocalParameter

304047
value: 0.0
type: LocalParameter

708080
stoichiometry: 1.0
species: 302498
type: SpeciesReference

720378
stoichiometry: 1.0
species: 302948
type: SpeciesReference

721173
stoichiometry: 1.0
species: 302965
type: SpeciesReference

305828
value: 0.0
type: LocalParameter

718637
stoichiometry: 1.0
species: 302440
type: SpeciesReference

721233
stoichiometry: 1.0
species: 302526
type: SpeciesReference

305613
value: 0.0
type: LocalParameter

304849
value: 0.0
type: LocalParameter

717661
stoichiometry: 1.0
species: 302853
type: SpeciesReference

302581
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Dephospho-CoA_C21H33N7O13P2S
type: Species

697532
stoichiometry: 1.0
species: 302516
type: SpeciesReference

697810
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305765
value: 0.0
type: LocalParameter

303260
type: Reaction
reactant: 702723
fast: false
reactant: 702711
product: 702747
product: 702735
name: dTMP kinase
kinetic law: 702759
reversible: true
notes: Abbreviation: R_DTMPK Synonyms: _0 EC Number: 2.7.4.9 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + dtmp <==> adp + dtdp Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:

703763
stoichiometry: 1.0
species: 302640
type: SpeciesReference

704163
stoichiometry: 1.0
species: 302704
type: SpeciesReference

304151
value: 0.0
type: LocalParameter

704273
stoichiometry: 1.0
species: 302728
type: SpeciesReference

717261
stoichiometry: 1.0
species: 302655
type: SpeciesReference

709013
stoichiometry: 1.0
species: 302697
type: SpeciesReference

721392
stoichiometry: 1.0
species: 302853
type: SpeciesReference

302502
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: _2-Oxoglutarate_C5H4O5
type: Species

303748
type: Reaction
reversible: false
kinetic law: 718990
product: 718978
reactant: 718929
product: 718954
notes: Abbreviation: R_SUCBZL Synonyms: _0 EC Number: 6.2.1.26 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : atp + coa + sucbz --> amp + ppi + sbzcoa Confidence Level: 2 genes: LOCUS:BLBBGE_271#ABBREVIATION:menE#ECNUMBERS:6.2.1.26# proteins: NAME:O-succinylbenzoate-CoA ligase#ABBREVIATION:MenE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_271)
reactant: 718942
product: 718966
name: o-succinylbenzoate-CoA ligase
fast: false
reactant: 718917

302430
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Octaprenyl-3-methyl-6-methoxy- 1,4-benzoquinol_C48H74O3
type: Species

302580
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Deamino-NAD+_C21H24N6O15P2
type: Species

696228
stoichiometry: 1.0
species: 302554
type: SpeciesReference

305764
value: 0.0
type: LocalParameter

304150
value: 999999.0
type: LocalParameter

305561
value: 0.0
type: LocalParameter

695299
stoichiometry: 1.0
species: 302676
type: SpeciesReference

700451
stoichiometry: 1.0
species: 302663
type: SpeciesReference

698317
stoichiometry: 0.229
species: 302519
type: SpeciesReference

302858
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (R)-Pantothenate_C9H16NO5
type: Species

695335
stoichiometry: 1.0
species: 302500
type: SpeciesReference

721380
stoichiometry: 1.0
species: 302659
type: SpeciesReference

714937
stoichiometry: 1.0
species: 302463
type: SpeciesReference

713407
stoichiometry: 1.0
species: 302734
type: SpeciesReference

303749
kinetic law: 719038
product: 719026
product: 719014
reactant: 719002
notes: Abbreviation: R_SUCBZS Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 2shchc --> h2o + sucbz Confidence Level: 2 genes: LOCUS:BLBBGE_270#ABBREVIATION:menC#ECNUMBERS:4.2.1.-# proteins: NAME:O-succinylbenzoate-CoA synthase#ABBREVIATION:MenC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_270)
fast: false
reversible: false
name: O-succinylbenzoate-CoA synthase
type: Reaction

305619
value: 0.0
type: LocalParameter

302503
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Alanine_C3H7NO2
type: Species

302583
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dTDP_C10H13N2O11P2
type: Species

305763
value: 999999.0
type: LocalParameter

720402
stoichiometry: 1.0
species: 302949
type: SpeciesReference

709690
stoichiometry: 1.0
species: 302698
type: SpeciesReference

302855
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Phosphate_HO4P
type: Species

704430
stoichiometry: 1.0
species: 303057
type: SpeciesReference

305562
value: 0.0
type: LocalParameter

700631
stoichiometry: 1.0
species: 302989
type: SpeciesReference

708758
stoichiometry: 1.0
species: 302444
type: SpeciesReference

700958
stoichiometry: 1.0
species: 302548
type: SpeciesReference

304778
value: 0.0
type: LocalParameter

303746
reactant: 718795
type: Reaction
product: 718832
notes: Abbreviation: R_SHSL1 Synonyms: _2 EC Number: 4.2.99.9 SUBSYSTEM: Methionine Metabolism Equation: [c] : cys-L + suchms --> cyst-L + h + succ Confidence Level: 2 new EC - EC 2.5.1.48 NJ genes: LOCUS:BLBBGE_568#ABBREVIATION:metBC#ECNUMBERS:2.5.1.48# proteins: NAME:Cystathionine gamma-synthase-cystathionine beta-lyase#ABBREVIATION:MetBC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_568)
product: 718820
product: 718808
fast: false
reversible: false
reactant: 718783
kinetic law: 718845
name: O-succinylhomoserine lyase (L-cysteine)

302500
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _2-Oxoglutarate_C5H4O5
type: Species

696156
stoichiometry: 1.0
species: 302498
type: SpeciesReference

699706
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305762
value: 0.0
type: LocalParameter

712243
stoichiometry: 1.0
species: 302853
type: SpeciesReference

305563
value: 999999.0
type: LocalParameter

697053
stoichiometry: 1.0
species: 302893
type: SpeciesReference

304779
value: 999999.0
type: LocalParameter

716177
stoichiometry: 1.0
species: 302605
type: SpeciesReference

305617
value: 999999.0
type: LocalParameter

303747
fast: false
reversible: false
reactant: 718857
kinetic law: 718905
notes: Abbreviation: R_SPODM Synonyms: _1 EC Number: 1.15.1.1 SUBSYSTEM: Unassigned Equation: [c] : (2) h + (2) o2s --> h2o2 + o2 Confidence Level: 2 JLR genes: LOCUS:BLBBGE_293#ABBREVIATION:sodA#ECNUMBERS:1.15.1.1# proteins: NAME:superoxide dismutase, Mn#ABBREVIATION:SodA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_293)
name: superoxide dismutase
product: 718881
product: 718893
type: Reaction
reactant: 718869

700007
stoichiometry: 1.0
species: 302738
type: SpeciesReference

718820
stoichiometry: 1.0
species: 302659
type: SpeciesReference

718857
stoichiometry: 2.0
species: 302659
type: SpeciesReference

697384
stoichiometry: 1.0
species: 302724
type: SpeciesReference

305073
value: 0.0
type: LocalParameter

304523
value: 0.0
type: LocalParameter

304383
value: 0.0
type: LocalParameter

303531
reactant: 710550
kinetic law: 710598
product: 710586
reactant: 710538
name: NAD diphosphatase
fast: false
product: 710562
type: Reaction
reversible: false
notes: Abbreviation: R_NADDP Synonyms: _0 EC Number: 3.6.1.22 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : h2o + nad --> amp + (2) h + nmn Confidence Level: 2 See also EC 3.6.1.9 genes: LOCUS:BLBBGE_333#ABBREVIATION:ligA#ECNUMBERS:6.5.1.2# proteins: NAME:DNA ligase#ABBREVIATION:Lig# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_333)
product: 710574

304278
value: 999999.0
type: LocalParameter

305268
value: 0.0
type: LocalParameter

303890
value: 0.0
type: LocalParameter

714433
stoichiometry: 1.0
species: 302720
type: SpeciesReference

303744
reactant: 718721
type: Reaction
fast: false
kinetic law: 718771
product: 718745
name: shikimate kinase
product: 718758
product: 718733
notes: Abbreviation: R_SHKK Synonyms: _0 EC Number: 2.7.1.71 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : atp + skm --> adp + h + skm5p Confidence Level: 2 genes: LOCUS:BLBBGE_430#ABBREVIATION:aroK#ECNUMBERS:2.7.1.71# proteins: NAME:Skikimic acid kinase I#ABBREVIATION:AroK# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_430)
reversible: false
reactant: 718709

702036
stoichiometry: 1.0
species: 302710
type: SpeciesReference

305821
value: 999999.0
type: LocalParameter

303826
value: 999999.0
type: LocalParameter

718795
stoichiometry: 1.0
species: 302929
type: SpeciesReference

715165
stoichiometry: 1.0
species: 302858
type: SpeciesReference

305407
value: 0.0
type: LocalParameter

707304
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304635
value: 0.0
type: LocalParameter

699031
stoichiometry: 1.0
species: 302489
type: SpeciesReference

304522
value: 999999.0
type: LocalParameter

304840
value: 0.0
type: LocalParameter

713043
stoichiometry: 1.0
species: 302865
type: SpeciesReference

305267
value: 0.0
type: LocalParameter

303530
kinetic law: 710526
product: 710514
reactant: 710502
notes: Abbreviation: R_NACUP Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: nac[e] --> nac[c] Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: false
name: Nicotinic acid uptake
type: Reaction

304277
value: 0.0
type: LocalParameter

304490
value: -999999.0
type: LocalParameter

305773
value: 0.0
type: LocalParameter

721512
stoichiometry: 1.0
species: 302973
type: SpeciesReference

304382
value: 999999.0
type: LocalParameter

714263
stoichiometry: 1.0
species: 302536
type: SpeciesReference

698872
stoichiometry: 1.0
species: 302511
type: SpeciesReference

303969
value: -999999.0
type: LocalParameter

303743
reactant: 718661
reactant: 718637
notes: Abbreviation: R_SHK3Dr Synonyms: _0 EC Number: 1.1.1.25 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : 3dhsk + h + nadph <==> nadp + skm Confidence Level: 2 JLR- added reversible form of SHK3D genes: LOCUS:BLBBGE_142#ABBREVIATION:ydiB#ECNUMBERS:1.1.1.25# proteins: NAME:putative shikimate 5-dehydrogenase#ABBREVIATION:YdiB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_142)
product: 718673
reactant: 718649
fast: false
kinetic law: 718697
name: shikimate dehydrogenase
type: Reaction
product: 718685
reversible: true

304634
value: 0.0
type: LocalParameter

722275
stoichiometry: 1.0
species: 302633
type: SpeciesReference

716802
stoichiometry: 1.0
species: 302581
type: SpeciesReference

305071
value: 0.0
type: LocalParameter

715429
stoichiometry: 1.0
species: 302541
type: SpeciesReference

303031
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Glycolate_C2H3O3
type: Species

305499
value: 999999.0
type: LocalParameter

707944
stoichiometry: 1.0
species: 302676
type: SpeciesReference

715539
stoichiometry: 1.0
species: 302433
type: SpeciesReference

304841
value: 0.0
type: LocalParameter

304521
value: 0.0
type: LocalParameter

305266
value: 999999.0
type: LocalParameter

303824
value: 0.0
type: LocalParameter

715213
stoichiometry: 1.0
species: 302659
type: SpeciesReference

706208
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303968
value: 0.0
type: LocalParameter

303742
reactant: 718577
product: 718613
reactant: 718565
type: Reaction
notes: Abbreviation: R_SHCHCS2 Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : ichor + ssaltpp --> 2shchc + pyr + thmpp Confidence Level: 2 JLR genes: LOCUS:BLBBGE_056#ABBREVIATION:menD#ECNUMBERS:4.1.1.71,-!-,2.2.1.9# proteins: NAME:bifunctional 2-oxoglutarate decarboxylase/2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase#ABBREVIATION:MenD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_056)
fast: false
product: 718601
kinetic law: 718625
product: 718589
reversible: false
name: _2-succinyl-6-hydroxy-2,4-cyclohexadiene 1-carboxylate synthase

721452
stoichiometry: 1.0
species: 302963
type: SpeciesReference

304842
value: 0.0
type: LocalParameter

304633
value: 999999.0
type: LocalParameter

701006
stoichiometry: 1.0
species: 302536
type: SpeciesReference

305409
value: 0.0
type: LocalParameter

709098
stoichiometry: 1.0
species: 302697
type: SpeciesReference

701769
stoichiometry: 1.0
species: 302723
type: SpeciesReference

716996
stoichiometry: 1.0
species: 302895
type: SpeciesReference

304279
value: 0.0
type: LocalParameter

710658
stoichiometry: 1.0
species: 302719
type: SpeciesReference

303032
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: H2O_H2O
type: Species

304520
value: 0.0
type: LocalParameter

304384
value: 0.0
type: LocalParameter

305265
value: -999999.0
type: LocalParameter

711141
stoichiometry: 1.0
species: 302493
type: SpeciesReference

705323
stoichiometry: 1.0
species: 302616
type: SpeciesReference

305771
value: 0.0
type: LocalParameter

302591
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: dUTP_C9H11N2O14P3
type: Species

699995
stoichiometry: 1.0
species: 302655
type: SpeciesReference

699055
stoichiometry: 5.0
species: 302697
type: SpeciesReference

702916
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304999
value: 999999.0
type: LocalParameter

700739
stoichiometry: 1.0
species: 302534
type: SpeciesReference

304843
value: 999999.0
type: LocalParameter

305826
value: -999999.0
type: LocalParameter

303821
value: 0.0
type: LocalParameter

718286
stoichiometry: 1.0
species: 302633
type: SpeciesReference

303967
value: 0.0
type: LocalParameter

304916
value: 0.0
type: LocalParameter

696372
stoichiometry: 1.0
species: 302853
type: SpeciesReference

303894
value: 999999.0
type: LocalParameter

303741
kinetic law: 718553
product: 718541
product: 718529
reactant: 718517
notes: Abbreviation: R_SHCHC Synonyms: _1 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 5ephchc --> 2shchc + pyr Confidence Level: 2 JLR genes: LOCUS:BLBBGE_131#ABBREVIATION:menH#ECNUMBERS:4.2.99.20# proteins: NAME:SHCHC cynthase#ABBREVIATION:MenH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_131)
fast: false
reversible: false
name: _2-succinyl-6-hydroxy-2,4-cyclohexadiene 1-carboxylate synthase
type: Reaction

698546
stoichiometry: 0.326
species: 302694
type: SpeciesReference

699911
stoichiometry: 1.0
species: 302539
type: SpeciesReference

303037
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Isoleucine_C6H13NO2
type: Species

305264
value: 0.0
type: LocalParameter

712303
stoichiometry: 1.0
species: 302559
type: SpeciesReference

304493
value: 0.0
type: LocalParameter

304639
value: 999999.0
type: LocalParameter

304998
value: 0.0
type: LocalParameter

304844
value: 0.0
type: LocalParameter

709231
stoichiometry: 1.0
species: 302536
type: SpeciesReference

695867
stoichiometry: 1.0
species: 302626
type: SpeciesReference

303966
value: 999999.0
type: LocalParameter

304917
value: 0.0
type: LocalParameter

708989
stoichiometry: 1.0
species: 302478
type: SpeciesReference

303822
value: 0.0
type: LocalParameter

305825
value: 0.0
type: LocalParameter

305556
value: -999999.0
type: LocalParameter

710948
stoichiometry: 1.0
species: 302493
type: SpeciesReference

713551
stoichiometry: 5.0
species: 302865
type: SpeciesReference

304494
value: 0.0
type: LocalParameter

710502
stoichiometry: 1.0
species: 302718
type: SpeciesReference

703545
stoichiometry: 1.0
species: 302609
type: SpeciesReference

305559
value: 0.0
type: LocalParameter

304845
value: 0.0
type: LocalParameter

709605
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304997
value: 0.0
type: LocalParameter

711578
stoichiometry: 1.0
species: 302587
type: SpeciesReference

303965
value: -999999.0
type: LocalParameter

304918
value: 0.0
type: LocalParameter

305262
value: 0.0
type: LocalParameter

304381
value: 0.0
type: LocalParameter

303892
value: -999999.0
type: LocalParameter

696444
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302969
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
type: Species

719641
stoichiometry: 1.0
species: 302655
type: SpeciesReference

706991
stoichiometry: 1.0
species: 302651
type: SpeciesReference

695555
stoichiometry: 1.0
species: 302686
type: SpeciesReference

303035
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: H+_H
type: Species

305558
value: 999999.0
type: LocalParameter

710440
stoichiometry: 1.0
species: 302482
type: SpeciesReference

304846
value: 0.0
type: LocalParameter

304996
value: 0.0
type: LocalParameter

304637
value: 0.0
type: LocalParameter

305823
value: 0.0
type: LocalParameter

303964
value: 0.0
type: LocalParameter

709473
stoichiometry: 1.0
species: 302853
type: SpeciesReference

303820
value: 999999.0
type: LocalParameter

304919
value: 999999.0
type: LocalParameter

708480
stoichiometry: 1.0
species: 302683
type: SpeciesReference

719182
stoichiometry: 1.0
species: 302710
type: SpeciesReference

304380
value: 0.0
type: LocalParameter

305261
value: 999999.0
type: LocalParameter

304492
value: 999999.0
type: LocalParameter

702843
stoichiometry: 1.0
species: 302589
type: SpeciesReference

302968
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
type: Species

303036
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Histidine_C6H9N3O2
type: Species

303146
notes: Abbreviation: R_ARGN Synonyms: _0 EC Number: 3.5.3.1 SUBSYSTEM: Urea cycle/amino group metabolism Equation: [c] : arg-L + h2o --> orn + urea Confidence Level: 2 genes: LOCUS:BLBBGE_059#ABBREVIATION:rocF,speB#ECNUMBERS:3.5.3.1# proteins: NAME:agmatinase#ABBREVIATION:rocF,speB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_059)
type: Reaction
name: arginase
reactant: 697592
reactant: 697604
fast: false
product: 697628
kinetic law: 697640
product: 697616
reversible: false

304497
value: 0.0
type: LocalParameter

305400
value: -999999.0
type: LocalParameter

701696
stoichiometry: 1.0
species: 302659
type: SpeciesReference

698104
stoichiometry: 1.0
species: 302738
type: SpeciesReference

303470
reversible: true
type: Reaction
product: 708395
reactant: 708371
notes: Abbreviation: R_ILETA Synonyms: _0 EC Number: 2.6.1.42 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : akg + ile-L <==> 3mop + glu-L Confidence Level: 2 genes: LOCUS:BLBBGE_455#ABBREVIATION:ilvE#ECNUMBERS:2.6.1.42,-!-,2.6.1.2# proteins: NAME:Branched-chain-amino-acid aminotransferase#ABBREVIATION:IlvE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_455)
product: 708383
kinetic law: 708407
name: isoleucine transaminase
reactant: 708359
fast: false

304781
value: 0.0
type: LocalParameter

304995
value: 999999.0
type: LocalParameter

705105
stoichiometry: 1.0
species: 302602
type: SpeciesReference

710887
stoichiometry: 1.0
species: 302423
type: SpeciesReference

302652
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Guanine_C5H5N5O
type: Species

698655
stoichiometry: 0.21
species: 302878
type: SpeciesReference

304270
value: 999999.0
type: LocalParameter

305186
value: 0.0
type: LocalParameter

303898
value: 999999.0
type: LocalParameter

695975
stoichiometry: 1.0
species: 302493
type: SpeciesReference

710116
stoichiometry: 1.0
species: 302663
type: SpeciesReference

304912
value: 0.0
type: LocalParameter

713902
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303539
notes: Abbreviation: R_NADH9 Synonyms: _0 EC Number: 1.6.5.3 SUBSYSTEM: Oxidative Phosphorylation Equation: [c] : 2dmmq8 + h + nadh --> 2dmmql8 + nad Confidence Level: 2 JLR genes: LOCUS:BLBBGE_193#ABBREVIATION:ndh#ECNUMBERS:1.16.1.-,-!-,1.6.99.3# proteins: NAME:NADH dehydrogenase II#ABBREVIATION:Ndh# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_193)
type: Reaction
fast: false
reactant: 710851
product: 710887
reversible: false
reactant: 710875
kinetic law: 710911
name: NADH dehydrogenase (demethylmenaquinone-8 & 0 protons)
product: 710899
reactant: 710863

712413
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303482
kinetic law: 708746
product: 708734
reactant: 708722
reactant: 708710
notes: Abbreviation: R_IPPMIb Synonyms: _0 EC Number: 4.2.1.33 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 2ippm + h2o <==> 3c3hmp Confidence Level: 2 Part of IPPMI (3-isopropylmalate dehydrogenase) enzyme added EC -NCD genes: LOCUS:BLBBGE_069#ABBREVIATION:leuD#ECNUMBERS:4.2.1.33,-!-,4.2.1.35# LOCUS:BLBBGE_068#ABBREVIATION:leuC#ECNUMBERS:4.2.1.33# proteins: NAME:Isopropylmalate isomerase small subunit#ABBREVIATION:LeuC# NAME:Isopropylmalate isomerase large subunit#ABBREVIATION:LeuD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_068 and BLBBGE_069)
fast: false
reversible: true
name: _2-isopropylmalate hydratase
type: Reaction

304498
value: 0.0
type: LocalParameter

707834
stoichiometry: 1.0
species: 302928
type: SpeciesReference

697749
stoichiometry: 1.0
species: 302518
type: SpeciesReference

303147
kinetic law: 697689
product: 697677
product: 697665
reactant: 697652
notes: Abbreviation: R_ARGSL Synonyms: _0 EC Number: 4.3.2.1 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : argsuc --> arg-L + fum Confidence Level: 2 genes: LOCUS:BLBBGE_364#ABBREVIATION:argH#ECNUMBERS:4.3.2.1# proteins: NAME:argininosuccinate lyase#ABBREVIATION:ArgH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_364)
fast: false
reversible: false
name: argininosuccinate lyase
type: Reaction

713346
stoichiometry: 1.0
species: 302651
type: SpeciesReference

304780
value: 0.0
type: LocalParameter

696796
stoichiometry: 1.0
species: 302500
type: SpeciesReference

304994
value: 0.0
type: LocalParameter

305494
value: 999999.0
type: LocalParameter

303683
reversible: false
reactant: 715600
kinetic law: 715649
notes: Abbreviation: R_PPNDH Synonyms: _0 EC Number: 4.2.1.51 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : h + pphn --> co2 + h2o + phpyr Confidence Level: 2 genes: LOCUS:BLBBGE_341#ABBREVIATION:pheA#ECNUMBERS:5.4.99.5,-!-,4.2.1.51# proteins: NAME:Chorismate mutase P#ABBREVIATION:PheA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_341)
product: 715612
reactant: 715588
name: prephenate dehydratase
fast: false
product: 715637
type: Reaction
product: 715624

713262
stoichiometry: 1.0
species: 302980
type: SpeciesReference

302651
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: GTP_C10H12N5O14P3
type: Species

696857
stoichiometry: 1.0
species: 302493
type: SpeciesReference

699475
stoichiometry: 1.0
species: 302664
type: SpeciesReference

703922
stoichiometry: 1.0
species: 303035
type: SpeciesReference

707015
stoichiometry: 1.0
species: 302497
type: SpeciesReference

303897
value: -999999.0
type: LocalParameter

718565
stoichiometry: 1.0
species: 302675
type: SpeciesReference

305187
value: -999999.0
type: LocalParameter

709862
stoichiometry: 1.0
species: 302723
type: SpeciesReference

302740
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)_C29H53N2O8PRS
type: Species

714155
stoichiometry: 0.72
species: 302750
type: SpeciesReference

716777
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303602
product: 712873
product: 712897
product: 712885
reactant: 712849
kinetic law: 712910
reactant: 712861
fast: false
name: Nucleoside triphosphate pyrophosphorylase (dctp)
notes: Abbreviation: R_NTPP3 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : dctp + h2o --> dcmp + h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
reversible: false
type: Reaction

709122
stoichiometry: 1.0
species: 302536
type: SpeciesReference

303538
type: Reaction
name: NADH dehydrogenase (demethylmenaquinone-8 & 2.8 protons)
product: 710802
reactant: 710766
reactant: 710778
product: 710827
notes: Abbreviation: R_NADH8 Synonyms: _0 EC Number: 1.6.5.3 SUBSYSTEM: Oxidative Phosphorylation Equation: _2dmmq8[c] + (3.8) h[c] + nadh[c] --> 2dmmql8[c] + (2.8) h[e] + nad[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_193#ABBREVIATION:ndh#ECNUMBERS:1.16.1.-,-!-,1.6.99.3# proteins: NAME:NADH dehydrogenase II#ABBREVIATION:Ndh# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_193)
product: 710814
reversible: false
fast: false
kinetic law: 710839
reactant: 710790

304913
value: 0.0
type: LocalParameter

304993
value: 0.0
type: LocalParameter

304495
value: 0.0
type: LocalParameter

302965
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
type: Species

303257
product: 702663
fast: false
kinetic law: 702699
reactant: 702627
name: diphosphomevalonate decarboxylase
product: 702687
type: Reaction
reversible: false
notes: Abbreviation: R_DPMVDx Synonyms: _0 EC Number: 4.1.1.33 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : 5dpmev + atp --> adp + co2 + ipdp + pi Confidence Level: 2 genes: LOCUS:BLBBGE_357#ABBREVIATION:mvaD#ECNUMBERS:4.1.1.33# proteins: NAME:diphosphomevalonate decarboxylase#ABBREVIATION:MvaD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_357)
reactant: 702639
product: 702675
product: 702651

303682
product: 715551
notes: Abbreviation: R_PPND Synonyms: _0 EC Number: 1.3.1.12 SUBSYSTEM: Tyrosine, Tryptophan, and Phenylalanine Metabolism Equation: [c] : nad + pphn --> 34hpp + co2 + nadh Confidence Level: 2 genes: LOCUS:BLBBGE_343#ABBREVIATION:tyrA#ECNUMBERS:5.4.99.5,-!-,1.3.1.12# proteins: NAME:Chorismate mutase T#ABBREVIATION:TyrA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_343)
name: prephenate dehydrogenase
product: 715564
kinetic law: 715576
reactant: 715527
reversible: false
fast: false
type: Reaction
product: 715539
reactant: 715515

305402
value: 0.0
type: LocalParameter

303144
kinetic law: 697580
reactant: 697532
notes: Abbreviation: R_ARGDC Synonyms: _0 EC Number: 4.1.1.19 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : arg-L + h --> agm + co2 Confidence Level: 2 genes: LOCUS:BLBBGE_060#ABBREVIATION:speA#ECNUMBERS:4.1.1.19# proteins: NAME:Arginine decarboxylase#ABBREVIATION:SpeA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_060)
name: arginine decarboxylase
type: Reaction
reactant: 697544
fast: false
product: 697568
product: 697556
reversible: false

304272
value: 0.0
type: LocalParameter

712181
stoichiometry: 1.0
species: 302686
type: SpeciesReference

302650
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Guanosine_C10H13N5O5
type: Species

711687
stoichiometry: 1.0
species: 302526
type: SpeciesReference

719750
stoichiometry: 1.0
species: 302943
type: SpeciesReference

303896
value: 0.0
type: LocalParameter

719266
stoichiometry: 1.0
species: 302493
type: SpeciesReference

713769
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305184
value: 999999.0
type: LocalParameter

304914
value: 0.0
type: LocalParameter

303603
type: Reaction
name: Nucleoside triphosphate pyrophosphorylase (ctp)
product: 712970
product: 712958
notes: Abbreviation: R_NTPP4 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : ctp + h2o --> cmp + h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
reversible: false
kinetic law: 712982
product: 712946
fast: false
reactant: 712922
reactant: 712934

304496
value: 999999.0
type: LocalParameter

304992
value: 0.0
type: LocalParameter

302964
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
type: Species

305401
value: 999999.0
type: LocalParameter

303895
value: 0.0
type: LocalParameter

699103
stoichiometry: 6.0
species: 302655
type: SpeciesReference

304271
value: 0.0
type: LocalParameter

709581
stoichiometry: 1.0
species: 302696
type: SpeciesReference

305492
value: 0.0
type: LocalParameter

697152
stoichiometry: 1.0
species: 302509
type: SpeciesReference

709715
stoichiometry: 1.0
species: 302487
type: SpeciesReference

304915
value: 999999.0
type: LocalParameter

305185
value: 0.0
type: LocalParameter

698196
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304528
value: 0.0
type: LocalParameter

720126
stoichiometry: 1.0
species: 302526
type: SpeciesReference

303474
kinetic law: 708541
reactant: 708480
type: Reaction
notes: Abbreviation: R_IMPD Synonyms: _0 EC Number: 1.1.1.205 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : h2o + imp + nad --> h + nadh + xmp Confidence Level: 2 genes: LOCUS:BLBBGE_160#ABBREVIATION:guaB#ECNUMBERS:1.1.1.205# proteins: NAME:Inosine-5'-monophosphate dehydrogenase#ABBREVIATION:GuaB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_160)
fast: false
product: 708516
product: 708528
reactant: 708492
reactant: 708468
reversible: false
product: 708504
name: IMP dehydrogenase

304632
value: -999999.0
type: LocalParameter

302963
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
type: Species

304274
value: 999999.0
type: LocalParameter

304991
value: 999999.0
type: LocalParameter

305497
value: 0.0
type: LocalParameter

714793
stoichiometry: 1.0
species: 302764
type: SpeciesReference

304527
value: 0.0
type: LocalParameter

303535
reactant: 710706
name: NADH dehydrogenase (menaquinone-8 & 2 protons)
fast: false
product: 710718
reactant: 710682
kinetic law: 710754
type: Reaction
product: 710742
notes: Abbreviation: R_NADH7 Synonyms: _0 EC Number: 1.6.5.3 SUBSYSTEM: Oxidative Phosphorylation Equation: (3) h[c] + mqn8[c] + nadh[c] --> (2) h[e] + mql8[c] + nad[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_193#ABBREVIATION:ndh#ECNUMBERS:1.16.1.-,-!-,1.6.99.3# proteins: NAME:NADH dehydrogenase II#ABBREVIATION:Ndh# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_193)
product: 710730
reversible: false
reactant: 710694

303829
value: 0.0
type: LocalParameter

305182
value: 0.0
type: LocalParameter

305404
value: 0.0
type: LocalParameter

716922
stoichiometry: 1.0
species: 302425
type: SpeciesReference

715105
stoichiometry: 1.0
species: 302659
type: SpeciesReference

715057
stoichiometry: 1.0
species: 302526
type: SpeciesReference

302656
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: H2O_H2O
type: Species

722022
stoichiometry: 1.0
species: 302588
type: SpeciesReference

305498
value: 0.0
type: LocalParameter

304273
value: 0.0
type: LocalParameter

703063
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304386
value: -999999.0
type: LocalParameter

304631
value: 0.0
type: LocalParameter

714721
stoichiometry: 1.0
species: 302431
type: SpeciesReference

706883
stoichiometry: 1.0
species: 302648
type: SpeciesReference

303030
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Glycerol_C3H8O3
type: Species

700091
stoichiometry: 1.0
species: 302655
type: SpeciesReference

303486
reactant: 708844
reactant: 708856
kinetic law: 708904
fast: false
reactant: 708868
product: 708892
name: acetohydroxy acid isomeroreductase
notes: Abbreviation: R_KARA1i Synonyms: _0 EC Number: 1.1.1.86 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : alac-S + h + nadph --> 23dhmb + nadp Confidence Level: 2 used to be named AHAI; renamed for consistency; irreversible form of KARA1i - NCD genes: LOCUS:BLBBGE_554#ABBREVIATION:ilvC#ECNUMBERS:1.1.1.86# proteins: NAME:acetohydroxy acid isomeroreductase#ABBREVIATION:IlvC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_554)
product: 708880
type: Reaction
reversible: false

303687
product: 715790
reactant: 715726
notes: Abbreviation: R_PRAGSr Synonyms: _1 EC Number: 6.3.4.13 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : atp + gly + pram --> adp + gar + h + pi Confidence Level: 2 JLR- added reversible form of PRAGS genes: LOCUS:BLBBGE_479#ABBREVIATION:purD#ECNUMBERS:6.3.4.13# proteins: NAME:Phosphoribosylglycinamide synthetase#ABBREVIATION:PurD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_479)
product: 715765
product: 715778
reactant: 715752
reactant: 715739
fast: false
kinetic law: 715814
type: Reaction
reversible: false
name: phosphoribosylglycinamide synthase
product: 715802

305070
value: 0.0
type: LocalParameter

303534
reactant: 710634
notes: Abbreviation: R_NADH10 Synonyms: _0 EC Number: 1.6.5.3 SUBSYSTEM: Oxidative Phosphorylation Equation: [c] : h + mqn8 + nadh --> mql8 + nad Confidence Level: 2 JLR genes: LOCUS:BLBBGE_193#ABBREVIATION:ndh#ECNUMBERS:1.16.1.-,-!-,1.6.99.3# proteins: NAME:NADH dehydrogenase II#ABBREVIATION:Ndh# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_193)
product: 710658
type: Reaction
product: 710646
reactant: 710610
fast: false
name: NADH dehydrogenase (menaquinone-8 & 0 protons)
reactant: 710622
kinetic law: 710670
reversible: false

304526
value: 999999.0
type: LocalParameter

305403
value: 0.0
type: LocalParameter

303606
name: Nucleoside triphosphate pyrophosphorylase (datp)
product: 713043
kinetic law: 713056
product: 713031
reversible: false
reactant: 713006
product: 713019
notes: Abbreviation: R_NTPP5 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : datp + h2o --> damp + h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
type: Reaction
fast: false
reactant: 712994

305183
value: 0.0
type: LocalParameter

302655
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: H2O_H2O
type: Species

698763
stoichiometry: 0.136
species: 302990
type: SpeciesReference

303686
name: Peptidoglycan subunit synthesis
fast: false
product: 715687
notes: Abbreviation: R_PPTGS_Bge Synonyms: _0 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : uaagmda --> h + peptido_Bge + udcpdp Confidence Level: 2 JLR- the production of a subunit of peptidoglycantv- H pylori also uses the same form genes: LOCUS:BLBBGE_284#ABBREVIATION:mrcA#ECNUMBERS:2.4.1.129# proteins: NAME:peptidoglycan synthetase; penicillin-binding protein 1A#ABBREVIATION:MrcA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_284)
reversible: false
product: 715700
reactant: 715662
product: 715675
kinetic law: 715713
type: Reaction

304389
value: 0.0
type: LocalParameter

305495
value: 0.0
type: LocalParameter

711963
stoichiometry: 1.0
species: 302865
type: SpeciesReference

303140
kinetic law: 697421
reversible: false
fast: false
notes: Abbreviation: R_APRAUR Synonyms: _0 EC Number: 1.1.1.193 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 5apru + h + nadph --> 5aprbu + nadp Confidence Level: 2 genes: LOCUS:BLBBGE_143#ABBREVIATION:ribD#ECNUMBERS:3.5.4.26,-!-,1.1.1.193# proteins: NAME:pyrimidine deaminase and pyrimidine reductase#ABBREVIATION:RibD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_143)
name: _5-amino-6-(5-phosphoribosylamino)uracil reductase
type: Reaction
reactant: 697360
product: 697396
reactant: 697372
reactant: 697384
product: 697408

304276
value: 0.0
type: LocalParameter

714877
stoichiometry: 3.0
species: 302714
type: SpeciesReference

696700
stoichiometry: 1.0
species: 302538
type: SpeciesReference

303483
notes: Abbreviation: R_IPPS Synonyms: _0 EC Number: 4.1.3.12 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 3mob + accoa + h2o --> 3c3hmp + coa + h Confidence Level: 2 genes: LOCUS:BLBBGE_067#ABBREVIATION:leuA#ECNUMBERS:4.1.3.12# proteins: NAME:Isopropylmalate synthase#ABBREVIATION:LeuA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_067)
product: 708820
name: _2-isopropylmalate synthase
reactant: 708770
type: Reaction
product: 708795
reactant: 708758
kinetic law: 708832
product: 708808
fast: false
reactant: 708783
reversible: false

304630
value: 0.0
type: LocalParameter

304499
value: 0.0
type: LocalParameter

305406
value: 0.0
type: LocalParameter

304525
value: 0.0
type: LocalParameter

303827
value: 0.0
type: LocalParameter

305180
value: 0.0
type: LocalParameter

305338
value: 0.0
type: LocalParameter

302654
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Hydrogen peroxide_H2O2
type: Species

708236
stoichiometry: 1.0
species: 302655
type: SpeciesReference

697495
stoichiometry: 1.0
species: 302659
type: SpeciesReference

702627
stoichiometry: 1.0
species: 302466
type: SpeciesReference

715802
stoichiometry: 1.0
species: 302853
type: SpeciesReference

711626
stoichiometry: 1.0
species: 302526
type: SpeciesReference

303607
fast: false
product: 713104
reactant: 713080
name: Nucleoside triphosphate pyrophosphorylase (atp)
product: 713092
product: 713116
notes: Abbreviation: R_NTPP6 Synonyms: _0 SUBSYSTEM: Nucleotide Salvage Pathway Equation: [c] : atp + h2o --> amp + h + ppi Confidence Level: 2 JLR genes: LOCUS:BLBBGE_405#ABBREVIATION:mazG# proteins: NAME:Nucleotide triphosphate pyrophosphohydrolase#ABBREVIATION:MazG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_405)
reactant: 713068
kinetic law: 713128
reversible: false
type: Reaction

303141
product: 697483
product: 697507
type: Reaction
product: 697471
reversible: false
fast: false
product: 697495
reactant: 697433
name: L-arginine transport via ABC system
kinetic law: 697520
reactant: 697446
reactant: 697458
notes: Abbreviation: R_ARGabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: arg-L[e] + atp[c] + h2o[c] --> adp[c] + arg-L[c] + h[c] + pi[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:

303471
kinetic law: 708456
product: 708444
product: 708431
reactant: 708419
notes: Abbreviation: R_IMPC Synonyms: _0 EC Number: 3.5.4.10 SUBSYSTEM: Purine and Pyrimidine Biosynthesis Equation: [c] : fprica --> h2o + imp Confidence Level: 2 genes: LOCUS:BLBBGE_480#ABBREVIATION:purH#ECNUMBERS:3.5.4.10,-!-,2.1.2.3# proteins: NAME:AICAR transformylase and IMP cyclohydrolase#ABBREVIATION:PurH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_480)
fast: false
reversible: false
name: IMP cyclohydrolase
type: Reaction

304388
value: 999999.0
type: LocalParameter

698909
stoichiometry: 1.0
species: 302489
type: SpeciesReference

304275
value: 0.0
type: LocalParameter

304524
value: 0.0
type: LocalParameter

305405
value: 999999.0
type: LocalParameter

302960
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
type: Species

304911
value: 999999.0
type: LocalParameter

305339
value: 0.0
type: LocalParameter

303828
value: 0.0
type: LocalParameter

708553
stoichiometry: 1.0
species: 302687
type: SpeciesReference

303899
value: 0.0
type: LocalParameter

709509
stoichiometry: 1.0
species: 302633
type: SpeciesReference

303306
kinetic law: 703824
product: 703812
reactant: 703800
notes: Abbreviation: R_EX_glyc_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : glyc <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Glycerol exchange
type: Reaction

706377
stoichiometry: 1.0
species: 302632
type: SpeciesReference

303129
kinetic law: 696942
product: 696930
reactant: 696918
notes: Abbreviation: R_ALAR Synonyms: _0 EC Number: 5.1.1.1 SUBSYSTEM: Alanine and Aspartate Metabolism Equation: [c] : ala-L <==> ala-D Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: alanine racemase
type: Reaction

708613
stoichiometry: 1.0
species: 302437
type: SpeciesReference

702361
stoichiometry: 1.0
species: 302579
type: SpeciesReference

706931
stoichiometry: 1.0
species: 302649
type: SpeciesReference

712861
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302758
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Pyridoxine 5'-phosphate_C8H10NO6P
type: Species

304762
value: 0.0
type: LocalParameter

698437
stoichiometry: 1.0E-5
species: 302598
type: SpeciesReference

305335
value: 999999.0
type: LocalParameter

699802
stoichiometry: 1.0
species: 302531
type: SpeciesReference

303274
kinetic law: 703243
product: 703231
reactant: 703219
notes: Abbreviation: R_EX_akg_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : akg <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: _2-Oxoglutarate exchange
type: Reaction

303451
product: 707773
reversible: false
product: 707785
product: 707798
name: homoserine kinase
reactant: 707761
type: Reaction
reactant: 707749
notes: Abbreviation: R_HSK Synonyms: _0 EC Number: 2.7.1.39 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : atp + hom-L --> adp + h + phom Confidence Level: 2 genes: LOCUS:BLBBGE_500#ABBREVIATION:thrB#ECNUMBERS:2.7.1.39# proteins: NAME:Homoserine kinase#ABBREVIATION:ThrB# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_500)
fast: false
kinetic law: 707810

304052
value: 999999.0
type: LocalParameter

304479
value: 0.0
type: LocalParameter

302444
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Methyl-2-oxobutanoate_C5H7O3
type: Species

719629
stoichiometry: 1.0
species: 302526
type: SpeciesReference

302759
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Phosphatidylethanolamine (Blattabacterium Blattella germanica)_C1936H3748N50O400P50
type: Species

304763
value: 0.0
type: LocalParameter

303273
kinetic law: 703207
product: 703195
reactant: 703183
notes: Abbreviation: R_EX_ac_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : ac <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Acetate exchange
type: Reaction

304051
value: -999999.0
type: LocalParameter

305334
value: 0.0
type: LocalParameter

713975
stoichiometry: 1.0
species: 302979
type: SpeciesReference

303487
reversible: false
reactant: 708941
notes: Abbreviation: R_KARA2i Synonyms: _0 EC Number: 1.1.1.86 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism Equation: [c] : 2ahbut + h + nadph --> 23dhmp + nadp Confidence Level: 2 JLR - added irreversible form of KARA2 genes: LOCUS:BLBBGE_554#ABBREVIATION:ilvC#ECNUMBERS:1.1.1.86# proteins: NAME:acetohydroxy acid isomeroreductase#ABBREVIATION:IlvC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_554)
type: Reaction
product: 708965
reactant: 708916
reactant: 708928
kinetic law: 708977
name: ketol-acid reductoisomerase (2-Aceto-2-hydroxybutanoate)
fast: false
product: 708953

302970
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: UDP-N-acetylmuramate_C20H28N3O19P2
type: Species

713635
stoichiometry: 1.0
species: 302428
type: SpeciesReference

718359
stoichiometry: 1.0
species: 302536
type: SpeciesReference

703617
stoichiometry: 1.0
species: 302618
type: SpeciesReference

305337
value: 0.0
type: LocalParameter

302445
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (S)-3-Methyl-2-oxopentanoate_C6H9O3
type: Species

715739
stoichiometry: 1.0
species: 302636
type: SpeciesReference

305620
value: 0.0
type: LocalParameter

697955
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304054
value: 0.0
type: LocalParameter

704066
stoichiometry: 1.0
species: 303041
type: SpeciesReference

712486
stoichiometry: 1.0
species: 302547
type: SpeciesReference

700163
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304765
value: 0.0
type: LocalParameter

695130
stoichiometry: 1.0
species: 302508
type: SpeciesReference

303309
kinetic law: 703860
product: 703848
reactant: 703836
notes: Abbreviation: R_EX_glyclt_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : glyclt <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Glycolate exchange
type: Reaction

719908
stoichiometry: 1.0
species: 302940
type: SpeciesReference

717032
stoichiometry: 1.0
species: 302853
type: SpeciesReference

302446
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Phospho-D-glycerate_C3H4O7P
type: Species

707172
stoichiometry: 1.0
species: 302725
type: SpeciesReference

304053
value: 0.0
type: LocalParameter

706557
stoichiometry: 1.0
species: 302708
type: SpeciesReference

303454
product: 707847
reactant: 707822
notes: Abbreviation: R_HSST Synonyms: _0 EC Number: 2.3.1.46 SUBSYSTEM: Methionine Metabolism Equation: [c] : hom-L + succoa --> coa + suchms Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 707859
reactant: 707834
type: Reaction
reversible: false
fast: false
name: homoserine O-succinyltransferase
kinetic law: 707872

702096
stoichiometry: 1.0
species: 302571
type: SpeciesReference

302447
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Phosphohydroxypyruvate_C3H2O7P
type: Species

305177
value: 0.0
type: LocalParameter

694839
stoichiometry: 1.0
species: 302493
type: SpeciesReference

702144
stoichiometry: 1.0
species: 302655
type: SpeciesReference

717781
stoichiometry: 1.0
species: 302948
type: SpeciesReference

303302
kinetic law: 703751
product: 703739
reactant: 703726
notes: Abbreviation: R_EX_gly_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : gly <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Glycine exchange
type: Reaction

303278
kinetic law: 703315
product: 703303
reactant: 703291
notes: Abbreviation: R_EX_arg_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : arg-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Arginine exchange
type: Reaction

303125
kinetic law: 696820
product: 696808
reactant: 696784
fast: false
notes: Abbreviation: R_AKGt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: akg[e] + h[e] <==> akg[c] + h[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
type: Reaction
name: _2-oxoglutarate reversible transport via symport
reversible: true
product: 696796
reactant: 696772

305331
value: 0.0
type: LocalParameter

303455
reactant: 707884
fast: false
kinetic law: 707932
product: 707920
product: 707908
notes: Abbreviation: R_HSTPT Synonyms: _0 EC Number: 2.6.1.9 SUBSYSTEM: Histidine Metabolism Equation: [c] : glu-L + imacp <==> akg + hisp Confidence Level: 2 genes: LOCUS:BLBBGE_435#ABBREVIATION:hisC#ECNUMBERS:2.6.1.9# proteins: NAME:Histidinol phosphate aminotransferase#ABBREVIATION:HisC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_435)
type: Reaction
name: histidinol-phosphate transaminase
reversible: true
reactant: 707896

711020
stoichiometry: 1.0
species: 302725
type: SpeciesReference

302754
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Adenosine 3',5'-bisphosphate_C10H11N5O10P2
type: Species

304056
value: 999999.0
type: LocalParameter

305622
value: 999999.0
type: LocalParameter

705433
stoichiometry: 1.0
species: 302617
type: SpeciesReference

304169
value: 0.0
type: LocalParameter

698812
stoichiometry: 45.5628
species: 302853
type: SpeciesReference

715960
stoichiometry: 1.0
species: 302870
type: SpeciesReference

716213
stoichiometry: 1.0
species: 302493
type: SpeciesReference

699319
stoichiometry: 6.0
species: 302487
type: SpeciesReference

703994
stoichiometry: 1.0
species: 303037
type: SpeciesReference

695747
stoichiometry: 1.0
species: 302451
type: SpeciesReference

706727
stoichiometry: 1.0
species: 302493
type: SpeciesReference

303277
kinetic law: 703279
product: 703267
reactant: 703255
notes: Abbreviation: R_EX_ala_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : ala-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Alanine exchange
type: Reaction

303124
reactant: 696700
fast: false
reactant: 696688
name: _2-Oxogluterate dehydrogenase
kinetic law: 696760
reactant: 696712
product: 696736
product: 696748
product: 696724
notes: Abbreviation: R_AKGDH Synonyms: _0 SUBSYSTEM: Citric Acid Cycle Equation: [c] : akg + coa + nad --> co2 + nadh + succoa Confidence Level: 2 Changed from TEST_AKGDH genes: LOCUS:BLBBGE_147#ABBREVIATION:lpd#ECNUMBERS:1.8.1.4# LOCUS:BLBBGE_214#ABBREVIATION:lpd#ECNUMBERS:1.8.1.4# LOCUS:BLBBGE_597#ABBREVIATION:sucA#ECNUMBERS:1.2.4.2# LOCUS:BLBBGE_596#ABBREVIATION:sucB#ECNUMBERS:2.3.1.61# LOCUS:BLBBGE_009#ABBREVIATION:sucB#ECNUMBERS:2.3.1.61# proteins: NAME:a-ketoglutarate, B#ABBREVIATION:SucB# NAME:a-ketoglutarate, B#ABBREVIATION:SucB# NAME:a-ketoglutarate dehydrogenase, A#ABBREVIATION:SucA# NAME:dihydrolipoamide dehydrogenase#ABBREVIATION:LpdA# NAME:dihydrolipoamide dehydrogenase#ABBREVIATION:LpdA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_596) or (BLBBGE_009) and (BLBBGE_147) or (BLBBGE_214) and (BLBBGE_597)
type: Reaction
reversible: false

696930
stoichiometry: 1.0
species: 302503
type: SpeciesReference

712620
stoichiometry: 1.0
species: 302853
type: SpeciesReference

302755
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3'-Phosphoadenylyl sulfate_C10H11N5O13P2S
type: Species

703473
stoichiometry: 1.0
species: 302572
type: SpeciesReference

704393
stoichiometry: 1.0
species: 303056
type: SpeciesReference

305621
value: -999999.0
type: LocalParameter

721853
stoichiometry: 1.0
species: 302671
type: SpeciesReference

304055
value: 0.0
type: LocalParameter

715887
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304168
value: 999999.0
type: LocalParameter

305624
value: 0.0
type: LocalParameter

305179
value: 999999.0
type: LocalParameter

302449
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-O-(1-Carboxyvinyl)-3-phosphoshikimate_C10H9O10P
type: Species

698015
stoichiometry: 1.0
species: 302660
type: SpeciesReference

715321
stoichiometry: 1.0
species: 302536
type: SpeciesReference

719956
stoichiometry: 1.0
species: 302620
type: SpeciesReference

304760
value: -999999.0
type: LocalParameter

305333
value: 0.0
type: LocalParameter

700223
stoichiometry: 2.0
species: 302659
type: SpeciesReference

699887
stoichiometry: 1.0
species: 302534
type: SpeciesReference

304058
value: 0.0
type: LocalParameter

702783
stoichiometry: 1.0
species: 302589
type: SpeciesReference

695409
stoichiometry: 1.0
species: 302487
type: SpeciesReference

705775
stoichiometry: 1.0
species: 302408
type: SpeciesReference

701175
stoichiometry: 1.0
species: 302608
type: SpeciesReference

711361
stoichiometry: 1.0
species: 302990
type: SpeciesReference

717829
stoichiometry: 1.0
species: 302561
type: SpeciesReference

714505
stoichiometry: 1.0
species: 302659
type: SpeciesReference

719557
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305623
value: 0.0
type: LocalParameter

303126
product: 696881
reactant: 696832
notes: Abbreviation: R_ALAALAr Synonyms: _0 EC Number: 6.3.2.4 SUBSYSTEM: Cell Envelope Biosynthesis Equation: [c] : (2) ala-D + atp --> adp + alaala + h + pi Confidence Level: 2 JLR- added reversible form of ALAALA genes: LOCUS:BLBBGE_126#ABBREVIATION:ddlB#ECNUMBERS:6.3.2.4# proteins: NAME:D-alanine-D-alanine ligase A#ABBREVIATION:DdlA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_126)
product: 696857
name: D-alanine-D-alanine ligase (reversible)
product: 696893
type: Reaction
reversible: false
fast: false
kinetic law: 696905
reactant: 696844
product: 696869

303458
type: Reaction
notes: Abbreviation: R_ICDHyr Synonyms: _0 EC Number: 1.1.1.42 SUBSYSTEM: Citric Acid Cycle Equation: [c] : icit + nadp --> akg + co2 + nadph Confidence Level: 2 Two reactions (ICDH1 and ICDH2) for isocitrate dehydrogenase genes: LOCUS:BLBBGE_272#ABBREVIATION:icd#ECNUMBERS:1.1.1.42# proteins: NAME:isocitrate dehydrogenase#ABBREVIATION:Icd# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_272)
reversible: false
fast: false
reactant: 707944
product: 707969
name: isocitrate dehydrogenase (NADP)
reactant: 707957
kinetic law: 708006
product: 707982
product: 707994

709849
stoichiometry: 1.0
species: 302698
type: SpeciesReference

303305
kinetic law: 703788
product: 703775
reactant: 703763
notes: Abbreviation: R_EX_glyald_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : glyald <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: D-Glyceraldehyde exchange
type: Reaction

704925
stoichiometry: 1.0
species: 302620
type: SpeciesReference

304761
value: 999999.0
type: LocalParameter

706667
stoichiometry: 1.0
species: 302642
type: SpeciesReference

720847
stoichiometry: 1.0
species: 302633
type: SpeciesReference

304057
value: 1.0
type: LocalParameter

705943
stoichiometry: 2.0
species: 302659
type: SpeciesReference

303972
value: 0.0
type: LocalParameter

705542
stoichiometry: 1.0
species: 302479
type: SpeciesReference

721647
stoichiometry: 1.0
species: 302526
type: SpeciesReference

698921
stoichiometry: 14.0
species: 302659
type: SpeciesReference

702554
stoichiometry: 1.0
species: 302526
type: SpeciesReference

706775
stoichiometry: 1.0
species: 302637
type: SpeciesReference

305554
value: 0.0
type: LocalParameter

706835
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302863
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Porphobilinogen_C10H13N2O4
type: Species

720270
stoichiometry: 1.0
species: 302708
type: SpeciesReference

695639
stoichiometry: 1.0
species: 302725
type: SpeciesReference

716321
stoichiometry: 1.0
species: 302660
type: SpeciesReference

305604
value: 0.0
type: LocalParameter

303459
kinetic law: 708043
product: 708031
reactant: 708018
notes: Abbreviation: R_ICHORSi Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : chor --> ichor Confidence Level: 2 JLR- added irreversible form of ICHORS genes: LOCUS:BLBBGE_192#ABBREVIATION:menF#ECNUMBERS:5.4.4.2# proteins: NAME:isochorismate synthase II#ABBREVIATION:EntC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_192)
fast: false
reversible: false
name: Isochorismate Synthase
type: Reaction

305815
value: 999999.0
type: LocalParameter

302516
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Arginine_C6H15N4O2
type: Species

305068
value: 0.0
type: LocalParameter

705081
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305626
value: 999999.0
type: LocalParameter

305779
value: 999999.0
type: LocalParameter

304164
value: 0.0
type: LocalParameter

305270
value: -999999.0
type: LocalParameter

304059
value: 0.0
type: LocalParameter

303015
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: (S)-Dihydroorotate_C5H5N2O4
type: Species

302864
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Prephenate_C10H8O6
type: Species

704176
stoichiometry: 1.0
species: 303046
type: SpeciesReference

304837
value: 0.0
type: LocalParameter

305603
value: 999999.0
type: LocalParameter

305816
value: 0.0
type: LocalParameter

721185
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302517
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Arginine_C6H15N4O2
type: Species

305067
value: 0.0
type: LocalParameter

303973
value: -999999.0
type: LocalParameter

305625
value: 0.0
type: LocalParameter

305778
value: 0.0
type: LocalParameter

302598
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2
type: Species

711505
stoichiometry: 1.0
species: 302526
type: SpeciesReference

696023
stoichiometry: 1.0
species: 302514
type: SpeciesReference

302597
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Fructose 6-phosphate_C6H11O9P
type: Species

305552
value: 999999.0
type: LocalParameter

719847
stoichiometry: 1.0
species: 302725
type: SpeciesReference

302865
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Diphosphate_HO7P2
type: Species

699778
stoichiometry: 1.0
species: 302853
type: SpeciesReference

721028
stoichiometry: 1.0
species: 302760
type: SpeciesReference

302518
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N(omega)-(L-Arginino)succinate_C10H17N4O6
type: Species

303018
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Fe2+_Fe
type: Species

707521
stoichiometry: 1.0
species: 302853
type: SpeciesReference

303974
value: 999999.0
type: LocalParameter

305817
value: 0.0
type: LocalParameter

719327
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305628
value: 0.0
type: LocalParameter

721755
stoichiometry: 1.0
species: 302475
type: SpeciesReference

305272
value: 999999.0
type: LocalParameter

304166
value: 0.0
type: LocalParameter

718118
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302596
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Fructose 1-phosphate_C6H11O9P
type: Species

305553
value: 0.0
type: LocalParameter

303301
kinetic law: 703714
product: 703701
reactant: 703689
notes: Abbreviation: R_EX_glu_L_LPAREN_e_RPAREN_ Synonyms: _0 Equation: [e] : glu-L <==> Confidence Level: genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: L-Glutamate exchange
type: Reaction

305601
value: 0.0
type: LocalParameter

699560
stoichiometry: 7.0
species: 302487
type: SpeciesReference

302519
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Asparagine_C4H8N2O3
type: Species

304835
value: 0.0
type: LocalParameter

715381
stoichiometry: 1.0
species: 302536
type: SpeciesReference

305069
value: 999999.0
type: LocalParameter

303975
value: 0.0
type: LocalParameter

305627
value: 0.0
type: LocalParameter

707749
stoichiometry: 1.0
species: 302526
type: SpeciesReference

701392
stoichiometry: 1.0
species: 302421
type: SpeciesReference

706449
stoichiometry: 1.0
species: 302659
type: SpeciesReference

304161
value: -999999.0
type: LocalParameter

305550
value: 0.0
type: LocalParameter

302595
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate_C6H9N2O6P
type: Species

712970
stoichiometry: 1.0
species: 302865
type: SpeciesReference

305775
value: 999999.0
type: LocalParameter

716669
stoichiometry: 1.0
species: 302905
type: SpeciesReference

303758
reactant: 719509
type: Reaction
notes: Abbreviation: R_TALA Synonyms: _0 EC Number: 2.2.1.2 SUBSYSTEM: Pentose Phosphate Pathway Equation: [c] : g3p + s7p <==> e4p + f6p Confidence Level: 2 SMP genes: LOCUS:BLBBGE_213#ABBREVIATION:tal#ECNUMBERS:2.2.1.2# proteins: NAME:transaldolase#ABBREVIATION:Tal# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_213)
product: 719521
reactant: 719497
product: 719533
name: transaldolase
fast: false
reversible: true
kinetic law: 719545

302512
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Anthranilate_C7H6NO2
type: Species

706220
stoichiometry: 1.0
species: 302723
type: SpeciesReference

305608
value: 999999.0
type: LocalParameter

305819
value: 0.0
type: LocalParameter

710730
stoichiometry: 1.0
species: 302709
type: SpeciesReference

304589
value: 0.0
type: LocalParameter

719738
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302868
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _5-Phospho-beta-D-ribosylamine_C5H11NO7P
type: Species

304588
value: 999999.0
type: LocalParameter

712255
stoichiometry: 1.0
species: 302989
type: SpeciesReference

304160
value: 0.0
type: LocalParameter

305551
value: 0.0
type: LocalParameter

305774
value: 0.0
type: LocalParameter

696168
stoichiometry: 1.0
species: 302617
type: SpeciesReference

701320
stoichiometry: 1.0
species: 302589
type: SpeciesReference

701248
stoichiometry: 1.0
species: 302588
type: SpeciesReference

714359
stoichiometry: 1.0
species: 302592
type: SpeciesReference

302440
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _3-Dehydroshikimate_C7H7O5
type: Species

706147
stoichiometry: 1.0
species: 302628
type: SpeciesReference

305629
value: -999999.0
type: LocalParameter

303759
reactant: 719557
reactant: 719581
reversible: true
kinetic law: 719617
type: Reaction
fast: false
product: 719593
product: 719605
reactant: 719569
name: tetrahydrodipicolinate succinylase
notes: Abbreviation: R_THDPS Synonyms: _0 EC Number: 2.3.1.117 SUBSYSTEM: Threonine and Lysine Metabolism Equation: [c] : h2o + succoa + thdp <==> coa + sl2a6o Confidence Level: 2 genes: LOCUS:BLBBGE_467#ABBREVIATION:dapD#ECNUMBERS:2.3.1.117# proteins: NAME:Tetrahydrodipicolinate N-succinultransferase#ABBREVIATION:DapD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_467)

302513
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: apoprotein [acyl carrier protein]_RHO
type: Species

305607
value: 0.0
type: LocalParameter

716165
stoichiometry: 1.0
species: 302526
type: SpeciesReference

697041
stoichiometry: 1.0
species: 302633
type: SpeciesReference

304767
value: 999999.0
type: LocalParameter

303019
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Formate_CH1O2
type: Species

717104
stoichiometry: 1.0
species: 302674
type: SpeciesReference

303272
kinetic law: 703171
product: 703159
product: 703147
reactant: 703135
notes: Abbreviation: R_ENO Synonyms: _0 EC Number: 4.2.1.11 SUBSYSTEM: Glycolysis/Gluconeogenesis Equation: [c] : 2pg <==> h2o + pep Confidence Level: 2 SMP genes: LOCUS:BLBBGE_264#ABBREVIATION:eno#ECNUMBERS:4.2.1.11# proteins: NAME:enolase#ABBREVIATION:Eno# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_264)
fast: false
reversible: true
name: enolase
type: Reaction

695359
stoichiometry: 1.0
species: 302633
type: SpeciesReference

704285
stoichiometry: 1.0
species: 303051
type: SpeciesReference

302869
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: N-(5-Phospho-D-ribosyl)anthranilate_C12H13NO9P
type: Species

302441
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: (R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]_C25H47N2O9PRS
type: Species

302593
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: D-Erythrose 4-phosphate_C4H7O7P
type: Species

304163
value: 0.0
type: LocalParameter

720499
stoichiometry: 1.0
species: 302442
type: SpeciesReference

303970
value: 999999.0
type: LocalParameter

697544
stoichiometry: 1.0
species: 302659
type: SpeciesReference

305777
value: 0.0
type: LocalParameter

718493
stoichiometry: 1.0
species: 302905
type: SpeciesReference

718202
stoichiometry: 1.0
species: 302655
type: SpeciesReference

302514
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Adenosine 5'-phosphosulfate_C10H12N5O10PS
type: Species

304768
value: 0.0
type: LocalParameter

709025
stoichiometry: 1.0
species: 302487
type: SpeciesReference

305606
value: 0.0
type: LocalParameter

304162
value: 999999.0
type: LocalParameter

695287
stoichiometry: 1.0
species: 302532
type: SpeciesReference

698209
stoichiometry: 4.0
species: 302660
type: SpeciesReference

695347
stoichiometry: 1.0
species: 302482
type: SpeciesReference

698329
stoichiometry: 0.229
species: 302522
type: SpeciesReference

302592
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: _1-deoxy-D-xylulose 5-phosphate_C5H9O7P
type: Species

302442
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: C'-(3-Indolyl)-glycerol 3-phosphate_C11H12NO6P
type: Species

305776
value: 0.0
type: LocalParameter

303971
value: 0.0
type: LocalParameter

304839
value: 999999.0
type: LocalParameter

713419
stoichiometry: 1.0
species: 302733
type: SpeciesReference

700945
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304769
value: 0.0
type: LocalParameter

722263
stoichiometry: 1.0
species: 302444
type: SpeciesReference

304989
value: 0.0
type: LocalParameter

304646
value: -999999.0
type: LocalParameter

303678
reactant: 715357
type: Reaction
reversible: false
name: phosphopantothenoylcysteine decarboxylase
notes: Abbreviation: R_PPCDC Synonyms: _0 EC Number: 4.1.1.36 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 4ppcys + h --> co2 + pan4p Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 715369
fast: false
product: 715393
product: 715381
kinetic law: 715405

714275
stoichiometry: 1.0
species: 302720
type: SpeciesReference

711723
stoichiometry: 1.0
species: 302551
type: SpeciesReference

698860
stoichiometry: 1.0
species: 302754
type: SpeciesReference

305782
value: 0.0
type: LocalParameter

722118
stoichiometry: 1.0
species: 302980
type: SpeciesReference

700379
stoichiometry: 1.0
species: 302475
type: SpeciesReference

712376
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304268
value: 0.0
type: LocalParameter

305278
value: 0.0
type: LocalParameter

716814
stoichiometry: 1.0
species: 302865
type: SpeciesReference

304533
value: 0.0
type: LocalParameter

305487
value: -999999.0
type: LocalParameter

304596
value: 999999.0
type: LocalParameter

304373
value: 0.0
type: LocalParameter

701805
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304645
value: 0.0
type: LocalParameter

701757
stoichiometry: 1.0
species: 302724
type: SpeciesReference

305060
value: 0.0
type: LocalParameter

715201
stoichiometry: 1.0
species: 302865
type: SpeciesReference

717539
stoichiometry: 1.0
species: 302526
type: SpeciesReference

708770
stoichiometry: 1.0
species: 302479
type: SpeciesReference

721440
stoichiometry: 1.0
species: 302724
type: SpeciesReference

707449
stoichiometry: 1.0
species: 302666
type: SpeciesReference

303812
value: 999999.0
type: LocalParameter

303754
reactant: 719230
reversible: true
product: 719278
type: Reaction
reactant: 719254
name: succinyl-CoA synthetase (ADP-forming)
fast: false
product: 719266
notes: Abbreviation: R_SUCOAS Synonyms: _0 EC Number: 6.2.1.5 SUBSYSTEM: Citric Acid Cycle Equation: [c] : atp + coa + succ <==> adp + pi + succoa Confidence Level: 2 genes: LOCUS:BLBBGE_591#ABBREVIATION:sucC#ECNUMBERS:6.2.1.5# LOCUS:BLBBGE_039#ABBREVIATION:sucD#ECNUMBERS:6.2.1.5# proteins: NAME:succinyl-CoA synthetase alpha chain#ABBREVIATION:SucD# NAME:succinyl-CoA synthetase beta chain#ABBREVIATION:SucC# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_591 and BLBBGE_039)
kinetic law: 719302
product: 719290
reactant: 719242

709400
stoichiometry: 1.0
species: 302526
type: SpeciesReference

699067
stoichiometry: 12.0
species: 302724
type: SpeciesReference

305783
value: 999999.0
type: LocalParameter

705299
stoichiometry: 1.0
species: 302608
type: SpeciesReference

303020
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: D-Fructose_C6H12O6
type: Species

701018
stoichiometry: 1.0
species: 302694
type: SpeciesReference

304372
value: 0.0
type: LocalParameter

304597
value: 0.0
type: LocalParameter

305488
value: 999999.0
type: LocalParameter

304532
value: 999999.0
type: LocalParameter

304830
value: 0.0
type: LocalParameter

305277
value: 999999.0
type: LocalParameter

304648
value: 0.0
type: LocalParameter

305549
value: 0.0
type: LocalParameter

305061
value: 999999.0
type: LocalParameter

719473
stoichiometry: 1.0
species: 302915
type: SpeciesReference

304535
value: 0.0
type: LocalParameter

708188
stoichiometry: 1.0
species: 302420
type: SpeciesReference

697372
stoichiometry: 1.0
species: 302659
type: SpeciesReference

697274
stoichiometry: 1.0
species: 302531
type: SpeciesReference

305810
value: -999999.0
type: LocalParameter

302511
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: AMP_C10H12N5O7P
type: Species

718832
stoichiometry: 1.0
species: 302924
type: SpeciesReference

303757
product: 719448
reactant: 719436
reversible: true
type: Reaction
reactant: 719424
product: 719473
notes: Abbreviation: R_SULR Synonyms: _0 EC Number: 1.8.2.2 SUBSYSTEM: Cysteine Metabolism Equation: [c] : (3) h2o + h2s + (3) nadp <==> (5) h + (3) nadph + so3 Confidence Level: 2 JLR- EC number is 1.8.1.2? genes: LOCUS:BLBBGE_280#ABBREVIATION:cysI#ECNUMBERS:1.8.1.2# LOCUS:BLBBGE_279#ABBREVIATION:cysJ#ECNUMBERS:1.8.1.2,-!-,1.6.8.1# proteins: NAME:sulfite reductase#ABBREVIATION:CysIJ# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_279 and BLBBGE_280)
name: sulfite reductase (NADPH2)
product: 719460
fast: false
reactant: 719412
kinetic law: 719485

303813
value: 0.0
type: LocalParameter

305609
value: 0.0
type: LocalParameter

700019
stoichiometry: 1.0
species: 302532
type: SpeciesReference

305784
value: 0.0
type: LocalParameter

714421
stoichiometry: 2.0
species: 302655
type: SpeciesReference

304371
value: 0.0
type: LocalParameter

305489
value: 0.0
type: LocalParameter

304598
value: 0.0
type: LocalParameter

304266
value: 0.0
type: LocalParameter

718783
stoichiometry: 1.0
species: 302542
type: SpeciesReference

303679
product: 715478
product: 715466
notes: Abbreviation: R_PPNCL2 Synonyms: _0 EC Number: 6.3.2.5 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 4ppan + ctp + cys-L --> 4ppcys + cmp + h + ppi Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
reactant: 715429
product: 715454
kinetic law: 715502
name: phosphopantothenate-cysteine ligase
reversible: false
fast: false
type: Reaction
reactant: 715441
product: 715490
reactant: 715417

304534
value: 0.0
type: LocalParameter

304647
value: 999999.0
type: LocalParameter

305062
value: 0.0
type: LocalParameter

305548
value: 999999.0
type: LocalParameter

303756
type: Reaction
fast: false
product: 719376
reactant: 719315
kinetic law: 719400
reactant: 719339
product: 719364
notes: Abbreviation: R_SULabc Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: atp[c] + h2o[c] + so4[e] --> adp[c] + h[c] + pi[c] + so4[c] Confidence Level: 1 genes: none proteins: none citations: none GENE ASSOCIATION:
product: 719351
reactant: 719327
reversible: false
name: sulfate transport via ABC system
product: 719388

304909
value: 0.0
type: LocalParameter

702024
stoichiometry: 1.0
species: 302571
type: SpeciesReference

303814
value: 0.0
type: LocalParameter

305785
value: 0.0
type: LocalParameter

721500
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304370
value: 999999.0
type: LocalParameter

706292
stoichiometry: 1.0
species: 302628
type: SpeciesReference

304599
value: -999999.0
type: LocalParameter

304265
value: 0.0
type: LocalParameter

699043
stoichiometry: 17.0
species: 302659
type: SpeciesReference

305279
value: 0.0
type: LocalParameter

305812
value: 0.0
type: LocalParameter

304906
value: 0.0
type: LocalParameter

304833
value: 999999.0
type: LocalParameter

305063
value: 0.0
type: LocalParameter

305547
value: -999999.0
type: LocalParameter

713866
stoichiometry: 1.0
species: 302865
type: SpeciesReference

709617
stoichiometry: 1.0
species: 302694
type: SpeciesReference

304985
value: 999999.0
type: LocalParameter

302860
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Porphobilinogen_C10H13N2O4
type: Species

710453
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304592
value: 999999.0
type: LocalParameter

695567
stoichiometry: 1.0
species: 302725
type: SpeciesReference

697408
stoichiometry: 1.0
species: 302723
type: SpeciesReference

303023
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Fumarate_C4H2O4
type: Species

696456
stoichiometry: 1.0
species: 302492
type: SpeciesReference

303751
product: 719086
name: succinate transport via proton symport (2 H)
notes: Abbreviation: R_SUCCt2_2 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: (2) h[e] + succ[e] --> (2) h[c] + succ[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_358#ABBREVIATION:dctA# proteins: NAME:C4-dicarboxylate transporter#ABBREVIATION:DctA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_358)
reactant: 719050
kinetic law: 719098
product: 719074
fast: false
type: Reaction
reactant: 719062
reversible: false

702855
stoichiometry: 1.0
species: 302853
type: SpeciesReference

305811
value: 999999.0
type: LocalParameter

303976
value: 0.0
type: LocalParameter

710392
stoichiometry: 1.0
species: 302720
type: SpeciesReference

304907
value: 0.0
type: LocalParameter

305546
value: 0.0
type: LocalParameter

305064
value: 0.0
type: LocalParameter

712109
stoichiometry: 1.0
species: 302998
type: SpeciesReference

304834
value: 0.0
type: LocalParameter

698293
stoichiometry: 0.001
species: 302511
type: SpeciesReference

304649
value: 0.0
type: LocalParameter

304593
value: 0.0
type: LocalParameter

304984
value: 0.0
type: LocalParameter

700583
stoichiometry: 1.0
species: 302546
type: SpeciesReference

303024
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Glutamine_C5H10N2O3
type: Species

698994
stoichiometry: 5.0
species: 302655
type: SpeciesReference

305273
value: 0.0
type: LocalParameter

719194
stoichiometry: 1.0
species: 302598
type: SpeciesReference

304480
value: 0.0
type: LocalParameter

303753
fast: false
kinetic law: 719218
type: Reaction
reversible: true
reactant: 719170
notes: Abbreviation: R_SUCD4 Synonyms: _0 SUBSYSTEM: Oxidative Phosphorylation Equation: [c] : fadh2 + mqn8 <==> fad + mql8 Confidence Level: 2 JLR genes: LOCUS:BLBBGE_151#ABBREVIATION:sdhC# LOCUS:BLBBGE_152#ABBREVIATION:sdhA#ECNUMBERS:1.3.99.1# LOCUS:BLBBGE_153#ABBREVIATION:sdhB#ECNUMBERS:1.3.99.1# proteins: NAME:succinate dehydrogenase#ABBREVIATION:Sdh# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_151 and BLBBGE_152 and BLBBGE_153)
product: 719194
name: succinate dehydrogenase
product: 719206
reactant: 719182

305065
value: 999999.0
type: LocalParameter

305814
value: 0.0
type: LocalParameter

699247
stoichiometry: 1.0
species: 302930
type: SpeciesReference

697761
stoichiometry: 1.0
species: 302659
type: SpeciesReference

696384
stoichiometry: 1.0
species: 302480
type: SpeciesReference

718274
stoichiometry: 1.0
species: 302913
type: SpeciesReference

710237
stoichiometry: 1.0
species: 302655
type: SpeciesReference

713805
stoichiometry: 1.0
species: 302980
type: SpeciesReference

304987
value: 0.0
type: LocalParameter

696650
stoichiometry: 1.0
species: 302465
type: SpeciesReference

702904
stoichiometry: 1.0
species: 302591
type: SpeciesReference

304904
value: 0.0
type: LocalParameter

700727
stoichiometry: 1.0
species: 302526
type: SpeciesReference

304831
value: 0.0
type: LocalParameter

303025
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Glutamate_C5H8NO4
type: Species

305276
value: -999999.0
type: LocalParameter

712596
stoichiometry: 1.0
species: 302655
type: SpeciesReference

304594
value: 0.0
type: LocalParameter

304481
value: -999999.0
type: LocalParameter

302660
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: H+_H
type: Species

305780
value: 0.0
type: LocalParameter

698534
stoichiometry: 0.428
species: 302692
type: SpeciesReference

699923
stoichiometry: 1.0
species: 302898
type: SpeciesReference

695855
stoichiometry: 1.0
species: 302493
type: SpeciesReference

303978
value: 0.0
type: LocalParameter

718420
stoichiometry: 1.0
species: 302488
type: SpeciesReference

304905
value: 999999.0
type: LocalParameter

303810
value: 0.0
type: LocalParameter

305066
value: 0.0
type: LocalParameter

305813
value: 0.0
type: LocalParameter

304986
value: 0.0
type: LocalParameter

716898
stoichiometry: 1.0
species: 302547
type: SpeciesReference

709243
stoichiometry: 1.0
species: 302723
type: SpeciesReference

304832
value: -999999.0
type: LocalParameter

305275
value: 0.0
type: LocalParameter

304530
value: 0.0
type: LocalParameter

305544
value: 0.0
type: LocalParameter

303026
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: Glycine_C2H5NO2
type: Species

304595
value: 0.0
type: LocalParameter

304482
value: 999999.0
type: LocalParameter

710514
stoichiometry: 1.0
species: 302717
type: SpeciesReference

303752
kinetic law: 719158
type: Reaction
product: 719134
reactant: 719122
product: 719146
notes: Abbreviation: R_SUCD1i Synonyms: _0 EC Number: 1.3.99.1 SUBSYSTEM: Citric Acid Cycle Equation: [c] : fad + succ <==> fadh2 + fum Confidence Level: 2 JLR - made an irreversible version of the SUCD1 reaction genes: LOCUS:BLBBGE_151#ABBREVIATION:sdhC# LOCUS:BLBBGE_152#ABBREVIATION:sdhA#ECNUMBERS:1.3.99.1# LOCUS:BLBBGE_153#ABBREVIATION:sdhB#ECNUMBERS:1.3.99.1# proteins: NAME:succinate dehydrogenase#ABBREVIATION:Sdh# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_151 and BLBBGE_152 and BLBBGE_153)
reversible: true
name: succinate dehydrogenase
reactant: 719110
fast: false

704565
stoichiometry: 1.0
species: 302908
type: SpeciesReference

303490
notes: Abbreviation: R_KAS14 Synonyms: _0 EC Number: 2.3.1.41 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : acACP + h + malACP --> ACP + actACP + co2 Confidence Level: 2 tvAMF genes: LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.179# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_079)
product: 709037
kinetic law: 709062
product: 709025
reactant: 709001
reactant: 708989
type: Reaction
product: 709050
name: beta-ketoacyl-ACP synthase
reactant: 709013
reversible: false
fast: false

305781
value: 0.0
type: LocalParameter

304260
value: 999999.0
type: LocalParameter

303491
reactant: 709074
fast: false
reactant: 709086
product: 709122
reversible: false
type: Reaction
product: 709110
name: beta-ketoacyl-ACP synthase (2)
kinetic law: 709147
product: 709134
reactant: 709098
notes: Abbreviation: R_KAS15 Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : accoa + h + malACP --> actACP + co2 + coa Confidence Level: 2 tvAMF genes: LOCUS:BLBBGE_111#ABBREVIATION:fabH#ECNUMBERS:2.3.1.41# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase#ABBREVIATION:FabH# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_111)

302662
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Bicarbonate_CHO3
type: Species

703050
stoichiometry: 1.0
species: 302593
type: SpeciesReference

304981
value: 999999.0
type: LocalParameter

304483
value: 0.0
type: LocalParameter

303670
product: 715153
notes: Abbreviation: R_PNTOt4 Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: na1[e] + pnto-R[e] --> na1[c] + pnto-R[c] Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
name: Pantothenate sodium symporter
reactant: 715129
kinetic law: 715177
type: Reaction
reversible: false
fast: false
product: 715165
reactant: 715141

700691
stoichiometry: 1.0
species: 302626
type: SpeciesReference

305172
value: 0.0
type: LocalParameter

304902
value: 0.0
type: LocalParameter

303269
type: Reaction
reactant: 703063
name: Erythrose 4-phosphate dehydrogenase
kinetic law: 703123
product: 703099
reactant: 703050
fast: false
notes: Abbreviation: R_E4PD Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : e4p + h2o + nad <==> 4per + (2) h + nadh Confidence Level: 2 JLR- Reaction from KEGG R01825 genes: LOCUS:BLBBGE_043#ABBREVIATION:gapA#ECNUMBERS:1.2.1.9# proteins: NAME:Erythrose-4-phosphate dehydrogenase#ABBREVIATION:gapA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_043)
reactant: 703075
product: 703111
reversible: true
product: 703087

706075
stoichiometry: 1.0
species: 302626
type: SpeciesReference

303819
value: 0.0
type: LocalParameter

719254
stoichiometry: 1.0
species: 302924
type: SpeciesReference

711699
stoichiometry: 1.0
species: 302548
type: SpeciesReference

696300
stoichiometry: 1.0
species: 302655
type: SpeciesReference

305480
value: 999999.0
type: LocalParameter

304484
value: 0.0
type: LocalParameter

304980
value: -999999.0
type: LocalParameter

305173
value: 0.0
type: LocalParameter

304903
value: 0.0
type: LocalParameter

709727
stoichiometry: 1.0
species: 302701
type: SpeciesReference

302750
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Palmitoyl-ACP (n-C16:0ACP)_C27H51N2O8PRS
type: Species

700619
stoichiometry: 1.0
species: 302725
type: SpeciesReference

697164
stoichiometry: 1.0
species: 302495
type: SpeciesReference

304590
value: 0.0
type: LocalParameter

305481
value: 0.0
type: LocalParameter

710875
stoichiometry: 1.0
species: 302720
type: SpeciesReference

698643
stoichiometry: 0.176
species: 302764
type: SpeciesReference

710802
stoichiometry: 1.0
species: 302423
type: SpeciesReference

304640
value: 0.0
type: LocalParameter

303134
reactant: 697090
kinetic law: 697127
fast: false
name: alanine transaminase
product: 697102
reactant: 697078
reversible: false
product: 697114
notes: Abbreviation: R_ALATA_L2 Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : ala-L + pydx5p --> pyam5p + pyr Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
type: Reaction

302753
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Pantetheine 4'-phosphate_C11H21N2O7PS
type: Species

302979
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
type: Species

701684
stoichiometry: 1.0
species: 302410
type: SpeciesReference

703689
stoichiometry: 1.0
species: 302634
type: SpeciesReference

304379
value: 0.0
type: LocalParameter

304983
value: 0.0
type: LocalParameter

304485
value: -999999.0
type: LocalParameter

713914
stoichiometry: 1.0
species: 302939
type: SpeciesReference

304900
value: 0.0
type: LocalParameter

703836
stoichiometry: 1.0
species: 302646
type: SpeciesReference

303527
reversible: false
product: 710478
fast: false
reactant: 710453
notes: Abbreviation: R_NACODA Synonyms: _0 SUBSYSTEM: Arginine and Proline Metabolism Equation: [c] : acg5sa + h2o --> ac + glu5sa Confidence Level: 0 JLR genes: LOCUS:BLBBGE_320#ABBREVIATION:argE#ECNUMBERS:3.5.1.16# proteins: NAME:acetylornithine deacetylase#ABBREVIATION:ArgE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_320)
reactant: 710440
product: 710466
kinetic law: 710490
name: N-acetylornithine deacetylase
type: Reaction

700439
stoichiometry: 1.0
species: 302655
type: SpeciesReference

695963
stoichiometry: 1.0
species: 302526
type: SpeciesReference

705191
stoichiometry: 1.0
species: 302598
type: SpeciesReference

709593
stoichiometry: 1.0
species: 302493
type: SpeciesReference

710128
stoichiometry: 1.0
species: 302702
type: SpeciesReference

302664
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)_C27H49N2O8PRS
type: Species

722191
stoichiometry: 1.0
species: 302659
type: SpeciesReference

302663
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Homocysteine_C4H9NO2S
type: Species

305482
value: 0.0
type: LocalParameter

304591
value: -999999.0
type: LocalParameter

699463
stoichiometry: 7.0
species: 302655
type: SpeciesReference

696869
stoichiometry: 1.0
species: 302507
type: SpeciesReference

712401
stoichiometry: 1.0
species: 302584
type: SpeciesReference

303494
product: 709219
reactant: 709183
kinetic law: 709255
product: 709243
product: 709231
fast: false
type: Reaction
notes: Abbreviation: R_KAS16 Synonyms: _0 SUBSYSTEM: Membrane Lipid Metabolism Equation: [c] : ddcaACP + (2) h + malACP + nadph --> 3hmrsACP + ACP + co2 + nadp Confidence Level: 2 JLR- takes C12:0-ACP fatty acid part way through the elongation cycle. genes: LOCUS:BLBBGE_057#ABBREVIATION:fabG#ECNUMBERS:1.1.1.100# LOCUS:BLBBGE_079#ABBREVIATION:fabF#ECNUMBERS:2.3.1.179# proteins: NAME:_3-oxoacyl-[acyl-carrier-protein] synthase II#ABBREVIATION:FabF# NAME:_3-oxoacyl-ACP reductase#ABBREVIATION:FabG# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_079) and (BLBBGE_057)
reactant: 709171
product: 709207
reversible: false
name: _3-hydroxy-myristoyl-ACP synthesis
reactant: 709195
reactant: 709159

304486
value: 999999.0
type: LocalParameter

303671
reversible: false
fast: false
product: 715225
notes: Abbreviation: R_PPA Synonyms: _3 EC Number: 3.6.1.1 SUBSYSTEM: Anaplerotic reactions Equation: [c] : h2o + ppi --> h + (2) pi Confidence Level: 2 genes: LOCUS:BLBBGE_010#ABBREVIATION:ppa#ECNUMBERS:3.6.1.1# proteins: NAME:inorganic pyrophosphatase#ABBREVIATION:Ppa# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_010)
name: inorganic diphosphatase
product: 715213
type: Reaction
reactant: 715189
kinetic law: 715237
reactant: 715201

303135
kinetic law: 697201
notes: Abbreviation: R_AMMQLT8 Synonyms: _0 SUBSYSTEM: Cofactor and Prosthetic Group Biosynthesis Equation: [c] : 2dmmql8 + amet --> ahcys + h + mql8 Confidence Level: 2 AMF genes: LOCUS:BLBBGE_110#ABBREVIATION:ubiE#ECNUMBERS:2.1.1.-# proteins: NAME:_2-DMK methyltransferase and 2-octaprenyl-6-methoxy-1,4-benzoquinonol methylase#ABBREVIATION:UbiE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_110)
reversible: false
product: 697164
name: S-adenosylmethione:2-demthylmenaquinole methyltransferase (menaquinone 8)
reactant: 697152
product: 697176
reactant: 697140
product: 697188
fast: false
type: Reaction

697737
stoichiometry: 1.0
species: 302511
type: SpeciesReference

707822
stoichiometry: 1.0
species: 302672
type: SpeciesReference

304378
value: 999999.0
type: LocalParameter

302978
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
type: Species

304982
value: 0.0
type: LocalParameter

714167
stoichiometry: 0.1
species: 302930
type: SpeciesReference

716789
stoichiometry: 1.0
species: 302753
type: SpeciesReference

718577
stoichiometry: 1.0
species: 302920
type: SpeciesReference

709134
stoichiometry: 1.0
species: 302538
type: SpeciesReference

701538
stoichiometry: 1.0
species: 302412
type: SpeciesReference

304901
value: 999999.0
type: LocalParameter

707027
stoichiometry: 1.0
species: 302608
type: SpeciesReference

303526
product: 710416
type: Reaction
reversible: true
name: _5,10-methylenetetrahydrofolate reductase (NADH)
reactant: 710379
reactant: 710392
product: 710404
kinetic law: 710428
reactant: 710366
fast: false
notes: Abbreviation: R_MTHFR2 Synonyms: _0 SUBSYSTEM: Folate Metabolism Equation: [c] : h + mlthf + nadh <==> 5mthf + nad Confidence Level: 2 tv genes: LOCUS:BLBBGE_445#ABBREVIATION:metF#ECNUMBERS:1.7.99.5# proteins: NAME:Methylenetetrahydrofolate reductase#ABBREVIATION:MetF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_445)

703910
stoichiometry: 1.0
species: 302660
type: SpeciesReference

708820
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303674
kinetic law: 715273
product: 715261
reactant: 715249
notes: Abbreviation: R_PPBNGt Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: ppbng[e] <==> ppbng[c] Confidence Level: 1 JLR genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
reversible: true
name: Phorphobilinogen transport
type: Reaction

304377
value: 0.0
type: LocalParameter

305483
value: 0.0
type: LocalParameter

716705
stoichiometry: 1.0
species: 302905
type: SpeciesReference

304487
value: 0.0
type: LocalParameter

304264
value: 999999.0
type: LocalParameter

304642
value: -999999.0
type: LocalParameter

302973
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Undecaprenyl diphosphate_C55H89O7P2
type: Species

696712
stoichiometry: 1.0
species: 302719
type: SpeciesReference

303495
name: ketohexokinase
type: Reaction
notes: Abbreviation: R_KHK Synonyms: _0 EC Number: 2.7.1.3 SUBSYSTEM: Fructose and Mannose Metabolism Equation: [c] : atp + fru --> adp + f1p + h Confidence Level: 2 genes: LOCUS:BLBBGE_008#ECNUMBERS:2.7.1.-# proteins: NAME:carbohydrate kinase citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_008)
reactant: 709279
product: 709315
kinetic law: 709327
fast: false
product: 709291
reactant: 709267
product: 709303
reversible: false

703255
stoichiometry: 1.0
species: 302506
type: SpeciesReference

697483
stoichiometry: 1.0
species: 302516
type: SpeciesReference

302666
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Histidine_C6H9N3O2
type: Species

702639
stoichiometry: 1.0
species: 302526
type: SpeciesReference

716008
stoichiometry: 1.0
species: 302522
type: SpeciesReference

303815
value: 0.0
type: LocalParameter

698751
stoichiometry: 0.131
species: 302954
type: SpeciesReference

708299
stoichiometry: 1.0
species: 302493
type: SpeciesReference

304537
value: 0.0
type: LocalParameter

305484
value: 999999.0
type: LocalParameter

304376
value: 0.0
type: LocalParameter

304641
value: 0.0
type: LocalParameter

304263
value: -999999.0
type: LocalParameter

304488
value: 0.0
type: LocalParameter

703267
stoichiometry: 1.0
species: 303005
type: SpeciesReference

719110
stoichiometry: 1.0
species: 302598
type: SpeciesReference

721597
stoichiometry: 8.0
species: 302865
type: SpeciesReference

304536
value: 999999.0
type: LocalParameter

305327
value: 0.0
type: LocalParameter

303816
value: 999999.0
type: LocalParameter

302975
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: UDP_C9H11N2O12P2
type: Species

705203
stoichiometry: 1.0
species: 302865
type: SpeciesReference

304375
value: 0.0
type: LocalParameter

304262
value: 0.0
type: LocalParameter

305485
value: 0.0
type: LocalParameter

303130
reactant: 696967
reactant: 696955
kinetic law: 697003
name: L-alanine reversible transport via proton symport
reversible: true
product: 696979
product: 696991
notes: Abbreviation: R_ALAt2r Synonyms: _0 SUBSYSTEM: Putative Transporters Equation: ala-L[e] + h[e] <==> ala-L[c] + h[c] Confidence Level: 1 NCD genes: none proteins: none citations: none GENE ASSOCIATION:
fast: false
type: Reaction

303462
kinetic law: 708128
notes: Abbreviation: R_IG3PS Synonyms: _0 SUBSYSTEM: Histidine Metabolism Equation: [c] : gln-L + prlp --> aicar + eig3p + glu-L + h Confidence Level: 2 Essential in L-histidine synthesis: No definite EC number assigned: EC 2.4.2.-; HisF cyclase genes: LOCUS:BLBBGE_437#ABBREVIATION:hisH#ECNUMBERS:2.4.2.-# LOCUS:BLBBGE_439#ABBREVIATION:hisF#ECNUMBERS:2.4.2.-# proteins: NAME:Imadazoleglycerol phosphate synthase#ABBREVIATION:HisF# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_437 and BLBBGE_439)
product: 708080
name: Imidazole-glycerol-3-phosphate synthase
product: 708092
product: 708116
product: 708104
reversible: false
fast: false
reactant: 708055
type: Reaction
reactant: 708068

720138
stoichiometry: 1.0
species: 302935
type: SpeciesReference

302668
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: L-Histidinol phosphate_C6H11N3O4P
type: Species

707677
stoichiometry: 1.0
species: 302524
type: SpeciesReference

715069
stoichiometry: 1.0
species: 302858
type: SpeciesReference

304539
value: -999999.0
type: LocalParameter

305328
value: -999999.0
type: LocalParameter

303523
reactant: 710287
reversible: true
reactant: 710301
notes: Abbreviation: R_MTHFD Synonyms: _0 EC Number: 1.5.1.5 SUBSYSTEM: Folate Metabolism Equation: [c] : mlthf + nadp <==> h + methf + nadph Confidence Level: 2 genes: LOCUS:BLBBGE_442#ABBREVIATION:folD#ECNUMBERS:1.5.1.5,-!-,3.5.4.9# proteins: NAME:Methylene-tetrahydrofolate dehydrogenase#ABBREVIATION:FolD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_442)
product: 710340
name: methylenetetrahydrofolate dehydrogenase (NADP)
fast: false
product: 710327
kinetic law: 710353
product: 710314
type: Reaction

303817
value: 0.0
type: LocalParameter

305170
value: 0.0
type: LocalParameter

708359
stoichiometry: 1.0
species: 302500
type: SpeciesReference

709923
stoichiometry: 1.0
species: 302526
type: SpeciesReference

716910
stoichiometry: 1.0
species: 302853
type: SpeciesReference

304644
value: 0.0
type: LocalParameter

304374
value: 999999.0
type: LocalParameter

304643
value: 999999.0
type: LocalParameter

302974
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302405
name: Undecaprenyl phosphate_C55H89O4P
type: Species

303498
product: 709364
type: Reaction
reactant: 709339
product: 709376
reversible: true
name: potassium reversible transport via proton symport
reactant: 709351
notes: Abbreviation: R_Kt2r Synonyms: _0 SUBSYSTEM: Transport, Extracellular Equation: h[e] + k[e] <==> h[c] + k[c] Confidence Level: 2 JLR genes: LOCUS:BLBBGE_574#ABBREVIATION:ktrB# LOCUS:BLBBGE_575#ABBREVIATION:ktrA# proteins: NAME:K+ uptake transporter subunit KtrB#ABBREVIATION:KtrB# NAME:K+ uptake transporter subunit KtrA#ABBREVIATION:KtrA# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_574) and (BLBBGE_575)
fast: false
kinetic law: 709388

704997
stoichiometry: 1.0
species: 302601
type: SpeciesReference

304050
value: 0.0
type: LocalParameter

303675
product: 715321
notes: Abbreviation: R_PPCK Synonyms: _0 EC Number: 4.1.1.49 SUBSYSTEM: Anaplerotic reactions Equation: [c] : atp + oaa --> adp + co2 + pep Confidence Level: 2 genes: LOCUS:BLBBGE_077#ABBREVIATION:pck#ECNUMBERS:4.1.1.49# proteins: NAME:phosphoenolpyruvate carboxykinase#ABBREVIATION:Pck# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_077)
reactant: 715285
type: Reaction
product: 715333
fast: false
product: 715309
reversible: false
reactant: 715297
kinetic law: 715345
name: phosphoenolpyruvate carboxykinase

702990
stoichiometry: 1.0
species: 302659
type: SpeciesReference

303131
reactant: 697016
type: Reaction
kinetic law: 697066
notes: Abbreviation: R_ALATA_L Synonyms: _0 EC Number: 2.6.1.2 SUBSYSTEM: Glutamate metabolism Equation: [c] : akg + ala-L <==> glu-L + pyr Confidence Level: 2 genes: LOCUS:BLBBGE_455#ABBREVIATION:ilvE#ECNUMBERS:2.6.1.42,-!-,2.6.1.2# proteins: NAME:Branched-chain-amino-acid aminotransferase#ABBREVIATION:IlvE# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_455)
product: 697053
name: L-alanine transaminase
reactant: 697028
fast: false
reversible: true
product: 697041

305486
value: 0.0
type: LocalParameter

706895
stoichiometry: 2.0
species: 302659
type: SpeciesReference

722034
stoichiometry: 1.0
species: 302493
type: SpeciesReference

703327
stoichiometry: 1.0
species: 302521
type: SpeciesReference

304261
value: 0.0
type: LocalParameter

707244
stoichiometry: 1.0
species: 302536
type: SpeciesReference

302667
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 302406
name: L-Histidine_C6H9N3O2
type: Species

303818
value: 0.0
type: LocalParameter

303522
kinetic law: 710274
product: 710261
reactant: 710249
reactant: 710237
notes: Abbreviation: R_MTHFC Synonyms: _0 EC Number: 3.5.4.9 SUBSYSTEM: Folate Metabolism Equation: [c] : h2o + methf <==> 10fthf Confidence Level: 2 genes: LOCUS:BLBBGE_442#ABBREVIATION:folD#ECNUMBERS:1.5.1.5,-!-,3.5.4.9# proteins: NAME:Methylene-tetrahydrofolate dehydrogenase#ABBREVIATION:FolD# citations: AUTHORS:Lopez-Sanchez,M.J.,Neef,A.,Pereto,J.,Patino-Navarrete,R.,Pignatelli,M.,Latorre,A. and Moya,A.#TITLE:Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica#JOURNAL:PLoS Genet.5:e1000721#YEAR:2009# GENE ASSOCIATION: (BLBBGE_442)
fast: false
reversible: true
name: methenyltetrahydrofolate cyclohydrolase
type: Reaction

304538
value: 0.0
type: LocalParameter

305329
value: 999999.0
type: LocalParameter

305171
value: 999999.0
type: LocalParameter